Search to RefSeq (Human) database
Query= 20030531C-000211 (20030531C-000211) 20030531C-000211
(1004 letters)
Database: RefSeq (Homo Sapiens/Amino Acid)
19,244 sequences; 10,046,356 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|4557327|ref|NP_000033.1| (NM_000042) beta-2-glycoprotein I p... 486 e-139
Alignment gi|4506877|ref|NP_002996.1| (NM_003005) selectin P precursor; S... 92 7e-19
Alignment gi|23503305|ref|NP_699197.1| (NM_153366) hypothetical protein F... 92 7e-19
Alignment gi|4506871|ref|NP_000441.1| (NM_000450) selectin E precursor; l... 87 2e-17
Alignment gi|4502503|ref|NP_000706.1| (NM_000715) complement component 4 ... 86 5e-17
Alignment gi|9961357|ref|NP_001985.1| (NM_001994) coagulation factor XIII... 85 7e-17
Alignment gi|15100168|ref|NP_150094.1| (NM_033225) CUB and Sushi multiple... 85 9e-17
Alignment gi|4504375|ref|NP_000177.1| (NM_000186) H factor 1 (complement)... 81 1e-15
Alignment gi|11321587|ref|NP_002104.1| (NM_002113) H factor (complement)-... 80 2e-15
Alignment gi|10834974|ref|NP_000564.1| (NM_000573) complement component (... 79 5e-15
>gi|4557327|ref|NP_000033.1| (NM_000042) beta-2-glycoprotein I
precursor [Homo sapiens]
Length = 345
Score = 486 bits (1252), Expect(2) = e-139
Identities = 222/287 (77%), Positives = 244/287 (84%)
Frame = +3
Query: 81 MIPPVLIFFLSFLCHAAIAGRTCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGG 260
MI PVLI F SFLCH AIAGRTCPKP++LPF+ VVPLK+ Y PGEEI Y+C+PGYVSRGG
Sbjct: 1 MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGG 60
Query: 261 IRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGAN 440
+R+FICPLTGLWPINTLKC PRVCPFAGILENGAVRYTTFEYPNTISF+CN GF L GA+
Sbjct: 61 MRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGAD 120
Query: 441 SAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAM 620
SAKCTEEGKWSP+L FA L VYKP AGNNSLY AVFECLPQHAM
Sbjct: 121 SAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAM 180
Query: 621 FGNGTITCTEHGNWTELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTL 800
FGN TITCT HGNWT+LPEC+EVKCPFPSRP+NGFVNYPAK LYY+DKAT+GCHD Y+L
Sbjct: 181 FGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL 240
Query: 801 DGPEEVECNKFGNWSAQPSCKASCKLSVKRATVIYEGERVNIQDKFK 941
DGPEE+EC K GNWSA PSCKASCKL VK+ATV+Y+GERV IQ+KFK
Sbjct: 241 DGPEEIECTKLGNWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFK 287
Score = 29.3 bits (64), Expect(2) = e-139
Identities = 11/12 (91%), Positives = 12/12 (99%)
Frame = +2
Query: 965 KISFFCKNKEKK 1000
K+SFFCKNKEKK
Sbjct: 295 KVSFFCKNKEKK 306
>gi|4506877|ref|NP_002996.1| (NM_003005) selectin P precursor;
Selectin P (granulocyte membrane protein, 140kD; antigen
CD62); selectin P (granule membrane protein 140kD,
antigen CD62); antigen CD62 [Homo sapiens]
Length = 830
Score = 91.7 bits (226), Expect = 7e-19
Identities = 63/246 (25%), Positives = 105/246 (42%), Gaps = 11/246 (4%)
Frame = +3
Query: 162 ELPFAVVV----PLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRV 329
ELP V++ PL +++ + + C GY G + C +G+W +CL
Sbjct: 204 ELPQHVLMNCSHPL-GNFSFNSQCSFHCTDGYQVNGP-SKLECLASGIWTNKPPQCLAAQ 261
Query: 330 CPFAGILENGAV----RYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXX 497
CP I E G + F++ ++ SF+C GF+L G +CT G W+
Sbjct: 262 CPPLKIPERGNMICLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKA 321
Query: 498 XXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELP 674
+ PL YG FEC P + + G + C + G+W+ LP
Sbjct: 322 VQCQHLEAPSEGTMDCVHPLTA--FAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLP 379
Query: 675 ECKEVKCPFPSRPENGFVN-YPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSA- 848
C+ + C P +G ++ P+ + Y ++ C + + L G + V C+ G W+A
Sbjct: 380 TCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAP 439
Query: 849 QPSCKA 866
P C+A
Sbjct: 440 APVCQA 445
Score = 90.1 bits (222), Expect = 2e-18
Identities = 68/247 (27%), Positives = 104/247 (41%), Gaps = 10/247 (4%)
Frame = +3
Query: 156 PEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLW--PINT---LKCL 320
P E V PL +++A G + CQPGY RG + C +G W P+ T + C
Sbjct: 330 PSEGTMDCVHPL-TAFAYGSSCKFECQPGYRVRG-LDMLRCIDSGHWSAPLPTCEAISCE 387
Query: 321 PRVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXX 500
P P G ++ F+Y SF C GF L+GA+ +C G+W+
Sbjct: 388 PLESPVHGSMDCSP-SLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQAL 446
Query: 501 XXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTEL-PE 677
A+++ P Y F C + G + C GNW + PE
Sbjct: 447 QCQDLPVPNEARVNCSHPFGAFR--YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPE 504
Query: 678 CKEVKCPFPSRPENGFVNYPAKQVL---YYQDKATYGCHDTYTLDGPEEVECNKFGNWS- 845
C+ + C P+NG + Q L Y+ + C + Y+L GPE ++C + G W+
Sbjct: 505 CQAIPCTPLLSPQNGTMT--CVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTD 562
Query: 846 AQPSCKA 866
+ P C+A
Sbjct: 563 SPPMCEA 569
Score = 85.9 bits (211), Expect = 4e-17
Identities = 60/227 (26%), Positives = 91/227 (39%), Gaps = 9/227 (3%)
Frame = +3
Query: 225 YTCQPGYVSRGG--IRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVR----YTTFEY 386
+ C G++ RG +R C G W C C + V + F Y
Sbjct: 414 FRCAEGFMLRGADIVR---CDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRY 470
Query: 387 PNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGN 566
+ SFTCN G L GA+ +C G W+ + ++ +PL
Sbjct: 471 QSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPL--G 528
Query: 567 NSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTELPE-CKEVKCPFPSRPENGFVN-YPA 740
+S Y F C +++ G + CT G WT+ P C+ +KCP PE G ++
Sbjct: 529 SSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDT 588
Query: 741 KQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSA-QPSCKASCKL 878
+ + C++ + L+GP VEC G WSA P+CK L
Sbjct: 589 RGEFNVGSTCHFSCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASL 635
Score = 79.7 bits (195), Expect = 3e-15
Identities = 68/275 (24%), Positives = 107/275 (38%), Gaps = 23/275 (8%)
Frame = +3
Query: 156 PEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCP 335
P+ V PL SS + + C GY S G R C +G W + C CP
Sbjct: 516 PQNGTMTCVQPLGSS-SYKSTCQFICDEGY-SLSGPERLDCTRSGRWTDSPPMCEAIKCP 573
Query: 336 FAGILENGAVRYTT----FEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXX 503
E G++ + F +T F+CN GF L+G N+ +CT G+WS
Sbjct: 574 ELFAPEQGSLDCSDTRGEFNVGSTCHFSCNNGFKLEGPNNVECTTSGRWSATPPTCKGIA 633
Query: 504 XXXXXXXKFAKLSVYKPLAGNNSLY----------GGKAVFECLPQHAMFGNGTITCTEH 653
+ L+ G ++Y F C + G+ T++C
Sbjct: 634 SLPTPGLQCPALTT----PGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPS 689
Query: 654 GNWTEL-PECKEVKC-------PFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGP 809
G WT + P C+ VKC P N + N+ Y ++ C + L+G
Sbjct: 690 GQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFS------YGSICSFHCLEGQLLNGS 743
Query: 810 EEVECNKFGNWSAQ-PSCKASCKLSVKRATVIYEG 911
+ C + G+WS P+C+A L+++ A + G
Sbjct: 744 AQTACQENGHWSTTVPTCQAG-PLTIQEALTYFGG 777
Score = 62.4 bits (150), Expect = 5e-10
Identities = 55/236 (23%), Positives = 85/236 (35%), Gaps = 22/236 (9%)
Frame = +3
Query: 225 YTCQPGYVSRGGIRRFICPLTGLW-----PINTLKCLPRVCPFAGILENGAVRYT----T 377
+TC G + G C TG W + C P + P +NG + +
Sbjct: 476 FTCNEGLLLVGA-SVLQCLATGNWNSVPPECQAIPCTPLLSP-----QNGTMTCVQPLGS 529
Query: 378 FEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPL 557
Y +T F C+ G+SL G CT G+W+ + L
Sbjct: 530 SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTR 589
Query: 558 AGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTELPE-CKEV--------KCPFPSR 710
N G F C + G + CT G W+ P CK + +CP +
Sbjct: 590 GEFN--VGSTCHFSCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGLQCPALTT 647
Query: 711 PENGFV---NYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSA-QPSCKA 866
P G + ++P + +GC+ +TL G + C G W+A P+C+A
Sbjct: 648 PGQGTMYCRHHPG--TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRA 701
Score = 56.2 bits (134), Expect = 3e-08
Identities = 47/183 (25%), Positives = 69/183 (37%), Gaps = 19/183 (10%)
Frame = +3
Query: 192 KSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKC-----LPRV---CPFAGI 347
+ + G ++C G+ G C +G W C LP CP
Sbjct: 589 RGEFNVGSTCHFSCNNGFKLEGP-NNVECTTSGRWSATPPTCKGIASLPTPGLQCPALTT 647
Query: 348 LENGAVRYT----TFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXX 515
G + TF + T F CN GF+L G ++ C G+W+
Sbjct: 648 PGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWT--------AVTPAC 699
Query: 516 XXXKFAKLSVYKPLAGN------NSLYGGKAVFECLPQHAMFGNGTITCTEHGNW-TELP 674
K ++L V KP+A N N YG F CL + G+ C E+G+W T +P
Sbjct: 700 RAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVP 759
Query: 675 ECK 683
C+
Sbjct: 760 TCQ 762
>gi|23503305|ref|NP_699197.1| (NM_153366) hypothetical protein
FLJ90754 [Homo sapiens]
Length = 1497
Score = 91.7 bits (226), Expect = 7e-19
Identities = 71/260 (27%), Positives = 103/260 (39%), Gaps = 16/260 (6%)
Frame = +3
Query: 144 TCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLP 323
+C KPE VV S Y I+Y C+PGY G R +C W C
Sbjct: 1166 SCGKPESPEHGFVVG--SKYTFESTIIYQCEPGYELEGNRER-VCQENRQWSGGVAICKE 1222
Query: 324 RVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXX 503
C NG + ++CNRG+SL+G + A CTE G WS +
Sbjct: 1223 TRCETQLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPV------- 1275
Query: 504 XXXXXXXKFAKLSVYKP-------LAGNNSLYGGKAVF-------ECLPQHAMFGNGTIT 641
+ KP + N+L K + +C + G+G IT
Sbjct: 1276 ------------PLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIIT 1323
Query: 642 CTEHGNWTELP-ECKEVKCPFPSRPENGFVNYPAKQVLY-YQDKATYGCHDTYTLDGPEE 815
WT+ +C+++ C P+ EN A+ V Y Y D TY C+ Y L+G
Sbjct: 1324 YNPDETWTQTSAKCEKISCGPPAHVENAI----ARGVHYQYGDMITYSCYSGYMLEGFLR 1379
Query: 816 VECNKFGNWSAQPSCKASCK 875
C + G W++ P C+A C+
Sbjct: 1380 SVCLENGTWTSPPICRAVCR 1399
Score = 89.0 bits (219), Expect = 5e-18
Identities = 59/226 (26%), Positives = 92/226 (40%), Gaps = 3/226 (1%)
Frame = +3
Query: 198 SYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLW-PINTLKCLPRVCPFAGILENGAVRYT 374
++ G ++ + C GY G + C +G W + KC+P CP +LEN V
Sbjct: 205 NFEVGSKVQFFCNEGYELVGD-SSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKE 263
Query: 375 TFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKP 554
++F+C G L+G + KC +W+ F P
Sbjct: 264 LTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFG-----VP 318
Query: 555 LAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTE-LPECKEVKCPFPSRPENGFVN 731
+ + +G + C+ + GN T C G W+ LPEC V+CP P NG ++
Sbjct: 319 IPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIID 378
Query: 732 YPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNW-SAQPSCKA 866
+ L Y A Y C + L G C + G+W +P+CKA
Sbjct: 379 V---RGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 421
Score = 88.2 bits (217), Expect = 8e-18
Identities = 63/242 (26%), Positives = 91/242 (37%), Gaps = 4/242 (1%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPR 326
C P + F V +P S+ G + Y+C G+ RG +C G W +C+P
Sbjct: 307 CTPPPLISFGVPIP-SSALHFGSTVKYSCVGGFFLRGNSTT-LCQPDGTWSSPLPECVPV 364
Query: 327 VCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKW---SPDLXXXXX 497
CP + NG + Y +T +TC GF L G + C E G W P
Sbjct: 365 ECPQPEEIPNGIIDVRGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIEC 424
Query: 498 XXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNW-TELP 674
KF+ ++ YG + C + G +TC E G+W + P
Sbjct: 425 LKPKEILNGKFSYTDLH---------YGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAP 475
Query: 675 ECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQP 854
C + C P ENGFV Y Y C + + G C + G S+ P
Sbjct: 476 SCNAIHCDSPQPIENGFVEGADYS---YGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIP 532
Query: 855 SC 860
+C
Sbjct: 533 TC 534
Score = 86.3 bits (212), Expect = 3e-17
Identities = 59/249 (23%), Positives = 94/249 (37%), Gaps = 9/249 (3%)
Frame = +3
Query: 144 TCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLP 323
+C P + AV +Y E+ C GY F C G W + C P
Sbjct: 1047 SCGSPPSVANAVATGEAHTYE--SEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSP 1104
Query: 324 RVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXX 503
+ CP + + V F +S +C G++ +G N + C +G W P
Sbjct: 1105 KKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPF------- 1157
Query: 504 XXXXXXXKFAKLSVYKP-------LAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNW 662
+ +S KP + G+ + +++C P + + GN C E+ W
Sbjct: 1158 ----SDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQW 1213
Query: 663 T-ELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGN 839
+ + CKE +C NG + + Y C+ Y+L+GP E C + G
Sbjct: 1214 SGGVAICKETRCETQLEFLNGKADIENRTT---GPNVVYSCNRGYSLEGPSEAHCTENGT 1270
Query: 840 WS-AQPSCK 863
WS P CK
Sbjct: 1271 WSHPVPLCK 1279
Score = 84.3 bits (207), Expect = 1e-16
Identities = 51/192 (26%), Positives = 79/192 (40%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPR 326
CP+PEE+P ++ +Y +YTC+PG+ G +C G W C
Sbjct: 366 CPQPEEIPNGIIDVRGLAYL--STALYTCKPGFELVGNTTT-LCGENGHWLGGKPTCKAI 422
Query: 327 VCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXX 506
C + NG YT Y T++++CNRGF L+G ++ C E G W D
Sbjct: 423 ECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 482
Query: 507 XXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTELPECKE 686
+ + G + YG ++ C P + G+ TC E G + +P C
Sbjct: 483 DSPQPIENGFVE------GADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTCMP 536
Query: 687 VKCPFPSRPENG 722
+ C P + G
Sbjct: 537 IDCGLPPHIDFG 548
Score = 81.3 bits (199), Expect = 1e-15
Identities = 62/232 (26%), Positives = 93/232 (39%), Gaps = 8/232 (3%)
Frame = +3
Query: 201 YAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYTTF 380
Y +EI YTC G++ G R +C G W T C+P C L NG +
Sbjct: 775 YTFQKEIEYTCNEGFLLEGARSR-VCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDY 833
Query: 381 EYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLA 560
+ ++F C+ G+ L GA C +G W ++ K + LA
Sbjct: 834 GFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEI-----------PLCKPVNCGPPEDLA 882
Query: 561 -----GNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPECKEVKCPFPSRPENG 722
G + ++GG ++C P + + GN + C +G+W+ P C +C P E G
Sbjct: 883 HGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPFRCSTPV-IEYG 941
Query: 723 FVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQ-PSCK-ASC 872
VN A C + L G E+ C G WS+ P C+ SC
Sbjct: 942 TVNGTDFDC---GKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC 990
Score = 80.1 bits (196), Expect = 2e-15
Identities = 58/234 (24%), Positives = 95/234 (39%), Gaps = 11/234 (4%)
Frame = +3
Query: 195 SSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYT 374
S+Y+ G + Y+C G+ +G ++ C +G W C P C +ENG + +T
Sbjct: 86 SNYSFGAMVAYSCNKGFYIKGE-KKSTCEASGQWSSPIPTCHPVSCGEPPKVENGFLEHT 144
Query: 375 TFE-YPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYK 551
T + + + + CN G+ G+ C W + + L K
Sbjct: 145 TGRIFESEVRYQCNPGYKPVGSPVFVCHANRHWHSE------------SPLMWVPLDCGK 192
Query: 552 P-------LAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTEL--PECKEVKCPFP 704
P + G N G K F C + + G+ + TC + G W + P+C KCP P
Sbjct: 193 PPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEP 252
Query: 705 SRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWS-AQPSCK 863
EN V K++ T+ C + + L GP ++C W+ + P CK
Sbjct: 253 PLLENQLV---LKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 303
Score = 79.3 bits (194), Expect = 4e-15
Identities = 66/264 (25%), Positives = 99/264 (37%), Gaps = 4/264 (1%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPR 326
C PE+L P S+ G I Y C PGY G R C G W ++ CLP
Sbjct: 875 CGPPEDLAHGF--PNGFSFIHGGHIQYQCFPGYKLHGNSSR-RCLSNGSWSGSSPSCLPF 931
Query: 327 VCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXX 506
C ++E G V T F+ C +GF L G + C +G+WS
Sbjct: 932 RCS-TPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC 990
Query: 507 XXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTE-LPECK 683
A +S +S + C + + G+ + CTE G W++ P C+
Sbjct: 991 GSLPMIPNAFIS------ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCE 1044
Query: 684 EVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLD-GPEEVECNKFGNWSAQP-S 857
+ C P N A Y+ + C + YT+D + C K G W + S
Sbjct: 1045 PLSCGSPPSVANAVATGEAHT---YESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERIS 1101
Query: 858 CK-ASCKLSVKRATVIYEGERVNI 926
C C L ++ G+ ++
Sbjct: 1102 CSPKKCPLPENITHILVHGDDFSV 1125
Score = 79.3 bits (194), Expect = 4e-15
Identities = 70/273 (25%), Positives = 101/273 (36%), Gaps = 10/273 (3%)
Frame = +3
Query: 123 HAAIAGRTCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPI 302
H +T +E P S++ G + YTC PGY G IC G
Sbjct: 579 HLGAVAKTWENTKESP----ATHSSNFLYGTMVSYTCNPGYELLGN-PVLICQEDGTRNG 633
Query: 303 NTLKCLPRVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDL 482
+ C+ C ENG +R+T + + ++C G L G+ C E KWS
Sbjct: 634 SAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILVGSGLRLCLENRKWS--- 690
Query: 483 XXXXXXXXXXXXXXKFAKLSVYKP-------LAGNNSLYGGKAVFECLPQHAMFGNGTIT 641
+ +S KP + G+N Y +EC P + + G T
Sbjct: 691 ----------GASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRT 740
Query: 642 CTEHGNWTE-LPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEV 818
C + NW E P C V P NG V +Q + Y C++ + L+G
Sbjct: 741 CQDDKNWDEDEPICIPVDRSSPPVSANGQVR---GDEYTFQKEIEYTCNEGFLLEGARSR 797
Query: 819 ECNKFGNWS-AQPSC-KASCKLSVKRATVIYEG 911
C G+WS A P C C + A + EG
Sbjct: 798 VCLANGSWSGATPDCVPVRCATPPQLANGVTEG 830
Score = 72.0 bits (175), Expect = 6e-13
Identities = 52/245 (21%), Positives = 102/245 (41%), Gaps = 7/245 (2%)
Frame = +3
Query: 147 CPKPEELPFAVVVPL-KSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPIN--TLKC 317
C KP + ++++ + K+ +A G + + C G+V + C G W + +++C
Sbjct: 9 CEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAK-IECMRGGQWNPSPMSIQC 67
Query: 318 LPRVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXX 497
+P C + NG + + + ++++CN+GF +KG + C G+WS +
Sbjct: 68 IPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEASGQWSSPIPTCHP 127
Query: 498 XXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNW-TELP 674
+ L ++ + ++C P + G+ C + +W +E P
Sbjct: 128 VSCGEPPKVENGFLE-----HTTGRIFESEVRYQCNPGYKPVGSPVFVCHANRHWHSESP 182
Query: 675 -ECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWS-- 845
+ C P +NGF+ +V K + C++ Y L G C K G W+
Sbjct: 183 LMWVPLDCGKPPPIQNGFMKGENFEV---GSKVQFFCNEGYELVGDSSWTCQKSGKWNKK 239
Query: 846 AQPSC 860
+ P C
Sbjct: 240 SNPKC 244
Score = 60.5 bits (145), Expect = 2e-09
Identities = 50/208 (24%), Positives = 75/208 (36%), Gaps = 3/208 (1%)
Frame = +3
Query: 258 GIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGA 437
G+ C G W C C ++ N + T+ N I+++C G+ ++G+
Sbjct: 966 GLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGS 1025
Query: 438 NSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLA-GNNSLYGGKAVFECLPQH 614
+ CTE+G WS + SV +A G Y + CL +
Sbjct: 1026 SDLICTEKGVWSQPYPVCEPLSCG-------SPPSVANAVATGEAHTYESEVKLRCLEGY 1078
Query: 615 AM-FGNGTITCTEHGNW-TELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHD 788
M T TC + G W E C KCP P + V+ V + + C +
Sbjct: 1079 TMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSV---NRQVSVSCAE 1135
Query: 789 TYTLDGPEEVECNKFGNWSAQPSCKASC 872
YT +G C G W P SC
Sbjct: 1136 GYTFEGVNISVCQLDGTWE-PPFSDESC 1162
Score = 57.8 bits (138), Expect = 1e-08
Identities = 37/165 (22%), Positives = 66/165 (39%), Gaps = 1/165 (0%)
Frame = +3
Query: 360 AVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKL 539
+V F + +SF C GF L + +C G+W+P +
Sbjct: 22 SVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSI--M 79
Query: 540 SVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTE-LPECKEVKCPFPSRPE 716
+ Y +G+N +G + C + G TC G W+ +P C V C P + E
Sbjct: 80 NGY--ASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEASGQWSSPIPTCHPVSCGEPPKVE 137
Query: 717 NGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQ 851
NGF+ + ++ ++ + Y C+ Y G C+ +W ++
Sbjct: 138 NGFLEHTTGRI--FESEVRYQCNPGYKPVGSPVFVCHANRHWHSE 180
>gi|4506871|ref|NP_000441.1| (NM_000450) selectin E precursor;
leukocyte endothelial cell adhesion molecule 2 [Homo
sapiens]
Length = 610
Score = 86.7 bits (213), Expect = 2e-17
Identities = 53/222 (23%), Positives = 91/222 (40%), Gaps = 9/222 (4%)
Frame = +3
Query: 225 YTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYT-----TFEYP 389
+ C+ G+ G + C +G W C C +NG+VR + F +
Sbjct: 270 FDCEEGFELMGA-QSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFK 328
Query: 390 NTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNN 569
++ +FTC GF L+G +CT +G+W+ + + ++ P A +
Sbjct: 329 SSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCL-PSASGS 387
Query: 570 SLYGGKAVFECLPQHAMFGNGTITCTEHGNW-TELPECKEVKCPFPSRPENGFVNYPAKQ 746
YG F C + G+ + C G W E P C+ V+C +P G V
Sbjct: 388 FRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSP 447
Query: 747 V--LYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQ-PSCK 863
+ Y+ + C + + L G ++EC G W+ + PSC+
Sbjct: 448 IGEFTYKSSCAFSCEEGFELYGSTQLECTSQGQWTEEVPSCQ 489
Score = 79.3 bits (194), Expect = 4e-15
Identities = 60/262 (22%), Positives = 94/262 (34%), Gaps = 8/262 (3%)
Frame = +3
Query: 105 FLSFLCHAAIAGRTCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPL 284
F C + PE PL +++ +C GY+ + C
Sbjct: 169 FSGLKCEQIVNCTALESPEHGSLVCSHPL-GNFSYNSSCSISCDRGYLP-SSMETMQCMS 226
Query: 285 TGLWPINTLKCLPRVCPFAGILENGAVRYT----TFEYPNTISFTCNRGFSLKGANSAKC 452
+G W C C NG V +F + T +F C GF L GA S +C
Sbjct: 227 SGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQC 286
Query: 453 TEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNG 632
T G W + + + AG + + F C + G
Sbjct: 287 TSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFT-FKSSCNFTCEEGFMLQGPA 345
Query: 633 TITCTEHGNWT-ELPECKEVKCPFPSRPENGFVNY--PAKQVLYYQDKATYGCHDTYTLD 803
+ CT G WT ++P C+ +C S PE G++N A Y + C + L
Sbjct: 346 QVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLK 405
Query: 804 GPEEVECNKFGNW-SAQPSCKA 866
G + ++C G W + +P+C+A
Sbjct: 406 GSKRLQCGPTGEWDNEKPTCEA 427
Score = 76.3 bits (186), Expect = 3e-14
Identities = 57/246 (23%), Positives = 98/246 (39%), Gaps = 14/246 (5%)
Frame = +3
Query: 189 LKSSYAPGEEIVY------TCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGIL 350
++ S++P E + TC+ G++ +G + C G W C C
Sbjct: 315 VRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQ-VECTTQGQWTQQIPVCEAFQCTALSNP 373
Query: 351 ENGAVRYT-----TFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXX 515
E G + +F Y ++ F+C +GF LKG+ +C G+W +
Sbjct: 374 ERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAV 433
Query: 516 XXX-KFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTE-LPECKEV 689
K + P+ Y F C ++G+ + CT G WTE +P C+ V
Sbjct: 434 HQPPKGLVRCAHSPIG--EFTYKSSCAFSCEEGFELYGSTQLECTSQGQWTEEVPSCQVV 491
Query: 690 KCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSA-QPSCKA 866
KC + P G +N + + C + +TL+G C G+WS P+C+A
Sbjct: 492 KCSSLAVP--GKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEA 549
Query: 867 SCKLSV 884
+ ++
Sbjct: 550 PTESNI 555
>gi|4502503|ref|NP_000706.1| (NM_000715) complement component 4
binding protein, alpha; Complement component 4-binding
protein, alpha polypeptide; complement component
4-binding protein, alpha [Homo sapiens]
Length = 597
Score = 85.5 bits (210), Expect = 5e-17
Identities = 62/248 (25%), Positives = 102/248 (41%), Gaps = 12/248 (4%)
Frame = +3
Query: 147 CPKPEELPFAVVVPL---KSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKC 317
C P L FA + + ++ + G + YTC PGYV + C G W NT C
Sbjct: 50 CGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTF-C 108
Query: 318 LPRVCPFAGILENGAVRY-TTFEYPNTISFTCNRGFSLKGANSAKCTEEGK---WSPDLX 485
+ + C G L NG V T + + I F+C+ GF L G+ +++C + + WS L
Sbjct: 109 IYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLP 168
Query: 486 XXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEH---- 653
+ + S + N YG + C P+ ++ G+ +I+CT
Sbjct: 169 QCEIVKCKPPPDIRNGRHSGEE----NFYAYGFSVTYSCDPRFSLLGHASISCTVENETI 224
Query: 654 GNW-TELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNK 830
G W P C+++ C P V+ + Y+D + C + L G + C+
Sbjct: 225 GVWRPSPPTCEKITCRKPDVSHGEMVS-GFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDA 283
Query: 831 FGNWSAQP 854
W+ P
Sbjct: 284 DSKWNPSP 291
Score = 68.2 bits (165), Expect = 9e-12
Identities = 60/247 (24%), Positives = 94/247 (37%), Gaps = 16/247 (6%)
Frame = +3
Query: 201 YAPGEEIVYTCQPGYVSRGGIRRFICPLT----GLWPINTLKCLPRVCPFAGILENGAVR 368
YA G + Y+C P + S G C + G+W + C C + V
Sbjct: 193 YAYGFSVTYSCDPRF-SLLGHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVS 251
Query: 369 Y--TTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLS 542
+ Y +TI F C +GF L+G++ C + KW+P A
Sbjct: 252 GFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWE 311
Query: 543 VY-KPLAGNNSLYGGKAVFECLPQHAMFGN--GTITCTEHGNWTELPECKEVKCPFPSRP 713
Y +P + + G + C P + + T+ C ++ WT C+ + CP P +
Sbjct: 312 TYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQGCEALCCPEP-KL 370
Query: 714 ENGFVNYPAKQ------VLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQ-PSCKASC 872
NG + K V +Y D+ ++ CH+T C G WS + PSC C
Sbjct: 371 NNGEITQHRKSRPANHCVYFYGDEISFSCHETSRF----SAICQGDGTWSPRTPSCGDIC 426
Query: 873 KLSVKRA 893
K A
Sbjct: 427 NFPPKIA 433
>gi|9961357|ref|NP_001985.1| (NM_001994) coagulation factor XIII B
subunit precursor; TGase [Homo sapiens]
Length = 661
Score = 85.1 bits (209), Expect = 7e-17
Identities = 66/225 (29%), Positives = 97/225 (42%), Gaps = 9/225 (4%)
Frame = +3
Query: 213 EEIVYTCQPGYVSRGGIR-RFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYT--TFE 383
+++ Y C GY + GG + + LT W + T KC C ++ENG T+E
Sbjct: 174 DKVQYECATGYYTAGGKKTEEVECLTYGWSL-TPKCTKLKCSSLRLIENGYFHPVKQTYE 232
Query: 384 YPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAG 563
+ + F C+ + L G++ +C G W P+ L + +
Sbjct: 233 EGDVVQFFCHENYYLSGSDLIQCYNFG-WYPE----SPVCEGRRNRCPPPPLPINSKIQT 287
Query: 564 NNSLY--GGKAVFECLPQHAMFGNGTITCTEHGNWTELPECKE----VKCPFPSRPENGF 725
+++ Y G EC + G+ I C E G WTE P+C E V C P ENG
Sbjct: 288 HSTTYRHGEIVHIECELNFEIHGSAEIRC-EDGKWTEPPKCIEGQEKVACEEPPFIENGA 346
Query: 726 VNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQPSC 860
N +K + Y DK TY C Y L G E+ CN+ G W+ P C
Sbjct: 347 ANLHSK-IYYNGDKVTYACKSGYLLHGSNEITCNR-GKWTLPPEC 389
Score = 67.8 bits (164), Expect = 1e-11
Identities = 62/260 (23%), Positives = 96/260 (36%), Gaps = 8/260 (3%)
Frame = +3
Query: 186 PLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTL------KCLPRVCPFAGI 347
P+K +Y G+ + + C Y G C G +P + + +C P P
Sbjct: 226 PVKQTYEEGDVVQFFCHENYYLSGS-DLIQCYNFGWYPESPVCEGRRNRCPPPPLPINSK 284
Query: 348 LENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXK 527
++ + TT+ + + C F + G+ +C E+GKW+
Sbjct: 285 IQTHS---TTYRHGEIVHIECELNFEIHGSAEIRC-EDGKWTEPPKCIEGQEKVACEEPP 340
Query: 528 FAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTELPECKE--VKCPF 701
F + L G K + C + + G+ ITC G WT PEC E C
Sbjct: 341 FIENGAAN-LHSKIYYNGDKVTYACKSGYLLHGSNEITCNR-GKWTLPPECVENNENCKH 398
Query: 702 PSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQPSCKASCKLS 881
P NG V Y C++ Y L G + C + G WS+ P C C ++
Sbjct: 399 PPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQ-GKWSSPPVCLEPCTVN 457
Query: 882 VKRATVIYEGERVNIQDKFK 941
V R NI+ K+K
Sbjct: 458 VDYM------NRNNIEMKWK 471
Score = 52.4 bits (124), Expect = 5e-07
Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Frame = +3
Query: 585 KAVFECLPQHAMFGNGT---ITCTEHGNWTELPECKEVKCPFPSRPENGFVNYPAKQVLY 755
K +EC + G + C +G W+ P+C ++KC ENG+ +P KQ
Sbjct: 175 KVQYECATGYYTAGGKKTEEVECLTYG-WSLTPKCTKLKCSSLRLIENGYF-HPVKQTYE 232
Query: 756 YQDKATYGCHDTYTLDGPEEVECNKFGNWSAQPSCK 863
D + CH+ Y L G + ++C FG + P C+
Sbjct: 233 EGDVVQFFCHENYYLSGSDLIQCYNFGWYPESPVCE 268
Score = 47.8 bits (112), Expect = 1e-05
Identities = 54/241 (22%), Positives = 88/241 (36%), Gaps = 14/241 (5%)
Frame = +3
Query: 201 YAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRV--CPFAGILENGAVR-- 368
Y G+++ Y C+ GY+ G C G W + +C+ C ++ NGAV
Sbjct: 354 YYNGDKVTYACKSGYLLHGS-NEITCN-RGKWTLPP-ECVENNENCKHPPVVMNGAVADG 410
Query: 369 -YTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWS--PDLXXXXXXXXXXXXXXKFAKL 539
++ +++ + CN + L+G+ ++C E+GKWS P
Sbjct: 411 ILASYATGSSVEYRCNEYYLLRGSKISRC-EQGKWSSPPVCLEPCTVNVDYMNRNNIEMK 469
Query: 540 SVYKPLAGNNSLYGGKAVFECLPQHAM-----FGNGTITCTEHGNWTELPECKEVK--CP 698
Y+ L+G F C + + ++ C L KE K C
Sbjct: 470 WKYE----GKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRGEVKYPLCTRKESKGMCT 525
Query: 699 FPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQPSCKASCKL 878
P ++G + Y C D + L+G E C G W+ P C C L
Sbjct: 526 SPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYCLD-GMWTTPPLCLEPCTL 584
Query: 879 S 881
S
Sbjct: 585 S 585
Score = 43.9 bits (102), Expect = 2e-04
Identities = 34/104 (32%), Positives = 48/104 (45%), Gaps = 3/104 (2%)
Frame = +3
Query: 639 TCTEHGNWTELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDG---P 809
TCT G W+ P C + KC P NG+++ K + Q+ YGC Y G
Sbjct: 75 TCTTEG-WSPEPRCFK-KCTKPDL-SNGYIS-DVKLLYKIQENMHYGCASGYKTTGGKDE 130
Query: 810 EEVECNKFGNWSAQPSCKASCKLSVKRATVIYEGERVNIQDKFK 941
E V+C G WS+QP+C+ + + A +Y G Q FK
Sbjct: 131 EVVQCLSDG-WSSQPTCRKEHETCL--APELYNGNYSTTQKTFK 171
>gi|15100168|ref|NP_150094.1| (NM_033225) CUB and Sushi multiple
domains 1 [Homo sapiens]
Length = 3508
Score = 84.7 bits (208), Expect = 9e-17
Identities = 57/218 (26%), Positives = 91/218 (41%), Gaps = 2/218 (0%)
Frame = +3
Query: 213 EEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYTTFEYPN 392
+ +VY C PG+ G R IC W T C+P C G +G + F +
Sbjct: 2644 DTVVYQCNPGFRLVGTSVR-ICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLND 2702
Query: 393 TISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNS 572
++FTCN G+ L+G + A+C G+WS L + A + + +
Sbjct: 2703 VVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENA-IRHGQQNFPESF 2761
Query: 573 LYGGKAVFECLPQHAMFGNGTITCTEHGNW-TELPECKEVKCPFPSRPENGFVNYPAKQV 749
YG ++ C + G+ +TC +G W LP+C + C P P N + ++
Sbjct: 2762 EYGMSILYHCKKGFHLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVL---TGEL 2818
Query: 750 LYYQDKATYGCHDTYTLDGPEEVECNKFGNWS-AQPSC 860
Y Y C + +L G + C + +WS A P C
Sbjct: 2819 FTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHC 2856
Score = 84.0 bits (206), Expect = 2e-16
Identities = 57/224 (25%), Positives = 93/224 (41%), Gaps = 10/224 (4%)
Frame = +3
Query: 219 IVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYTTFEYPNTI 398
++Y C GY + G + R C G W C C G L NG T F + T+
Sbjct: 2945 VIYACWEGYKTSGLMTRH-CTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTV 3003
Query: 399 SFTCNRGFSLKGANSA--KCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKP------ 554
S+ CN G+ ++ SA +CT++G+W+P A L P
Sbjct: 3004 SYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCK------------AVLCPQPPPVQNGT 3051
Query: 555 LAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPECKEVKCPFPSRPENGFVN 731
+ G++ +G + C+ + + + ++C G W E+P+C V C P P G +
Sbjct: 3052 VEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRL- 3110
Query: 732 YPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSA-QPSC 860
+ + Y+ + + C + L G C G WS QP+C
Sbjct: 3111 --SGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTC 3152
Score = 67.4 bits (163), Expect = 2e-11
Identities = 61/262 (23%), Positives = 99/262 (37%), Gaps = 15/262 (5%)
Frame = +3
Query: 192 KSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGL----WPINTLKCLPRVCPFAGILENG 359
+++ A G ++ Y C+PGY G C L W T C C NG
Sbjct: 2448 RTAGAVGSKVHYFCKPGY-RMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNG 2506
Query: 360 AVRYTTFEYPNTISFTCNRGFSLKGANSAK--CTEEGKWS----PDLXXXXXXXXXXXXX 521
+ F + + + C+ GF L+ + A C E+G WS P +
Sbjct: 2507 SFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPMCKPVACPSIEAQL 2566
Query: 522 XKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT---ELPECKEVK 692
+ +++ ++G+ + YG + + C P + + G + C +G W E P C+
Sbjct: 2567 SEHV---IWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRAGH 2623
Query: 693 CPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQ-PSC-KA 866
C P NG ++ Y+D Y C+ + L G C + WS Q P C
Sbjct: 2624 CGSPDPIVNGHISGDG---FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPI 2680
Query: 867 SCKLSVKRATVIYEGERVNIQD 932
+C A G N+ D
Sbjct: 2681 TCGHPGNPAHGFTNGSEFNLND 2702
Score = 65.5 bits (158), Expect = 6e-11
Identities = 61/244 (25%), Positives = 89/244 (36%), Gaps = 4/244 (1%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGY-VSRGGIRRFICPLTGLWPINTLKCLP 323
CP+P + V S + G I Y+C GY +S I C G+W +CLP
Sbjct: 3041 CPQPPPVQNGTVEG--SDFRWGSSISYSCMDGYQLSHSAI--LSCEGRGVWKGEIPQCLP 3096
Query: 324 RVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXX 503
C GI G + +F Y + + F C F L G++ C +G WS
Sbjct: 3097 VFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPA 3156
Query: 504 XXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTEL-PEC 680
+ G G F C + + G+ T TC + W+ + EC
Sbjct: 3157 HNTCPDPGTPHFGIQNSSRGYE--VGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTEC 3214
Query: 681 KEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTL-DGPEEVECNKFGNWSAQ-P 854
C P P + V A + + Y CH + L G E C W+ + P
Sbjct: 3215 IPHACRQPETPAHADVR--AIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSP 3272
Query: 855 SCKA 866
CK+
Sbjct: 3273 VCKS 3276
Score = 64.7 bits (156), Expect = 1e-10
Identities = 52/224 (23%), Positives = 81/224 (35%), Gaps = 10/224 (4%)
Frame = +3
Query: 219 IVYTCQPGYVSRGGIRRFI-CPLTGLWPINTLKCLPRVCPFAGILENGAVRYTTFEYPNT 395
+ Y C PGYV I C G W + C +CP ++NG V + F + ++
Sbjct: 3003 VSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSS 3062
Query: 396 ISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSL 575
IS++C G+ L + C G W ++ +LS G +
Sbjct: 3063 ISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLS------GKSFT 3116
Query: 576 YGGKAVFECLPQHAMFGNGTITCTEHGNWTEL-PECKEV---KCPFPSRPENGFVN---- 731
Y + F+C + G+ C G W+ + P C + CP P P G N
Sbjct: 3117 YKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRG 3176
Query: 732 YPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSA-QPSC 860
Y ++++ C Y + G C WS Q C
Sbjct: 3177 YEVGSTVFFR------CRKGYHIQGSTTRTCLANLTWSGIQTEC 3214
Score = 53.9 bits (128), Expect = 2e-07
Identities = 49/226 (21%), Positives = 83/226 (36%), Gaps = 7/226 (3%)
Frame = +3
Query: 210 GEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCL---PRVCPFAGILENGAVRYTTF 380
G + Y+C+ G S G +C W C P C G +G+ F
Sbjct: 2822 GAVVHYSCR-GSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDF 2880
Query: 381 EYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLA 560
+ + + F+C G L+G+ C G WS + ++
Sbjct: 2881 KTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMI-----VS 2935
Query: 561 GNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPECKEVKCPFPSRPENGFVNYP 737
+ L+ ++ C + G T CT +G WT P+C + C P NG + +
Sbjct: 2936 SDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANG-IQFG 2994
Query: 738 AKQVLYYQDKATYGCHDTYTLDG--PEEVECNKFGNWS-AQPSCKA 866
+ +Y C+ Y ++ + C K G W+ ++P CKA
Sbjct: 2995 TD--FTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKA 3038
Score = 33.9 bits (76), Expect = 0.18
Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Frame = +3
Query: 537 LSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPECKEVKCPFPSRP 713
+ Y G++ L+G FEC + G ITC ++ W+ P C C F
Sbjct: 533 IPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC-VFSCFFNFTA 591
Query: 714 ENGFV---NYP 737
+G + NYP
Sbjct: 592 SSGIILSPNYP 602
Score = 32.0 bits (71), Expect = 0.70
Identities = 18/57 (31%), Positives = 27/57 (46%), Gaps = 4/57 (7%)
Frame = +3
Query: 579 GGKAVFECLPQHAMFGNGTITCTEHG---NWT-ELPECKEVKCPFPSRPENGFVNYP 737
G FEC P + + G+ +TC +HG NW P C + C + +NG + P
Sbjct: 2108 GQSVSFECYPGYILIGHPVLTC-QHGINRNWNYPFPRC-DAPCGYNVTSQNGTIYSP 2162
Score = 31.6 bits (70), Expect = 0.91
Identities = 18/50 (36%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Frame = +3
Query: 771 TYGCHDTYTLDGPEEVECNKFGNWS-AQPSCKASC--KLSVKRATVIYEG 911
T+ C YTL E + C + W+ A PSC A C + K TV+ G
Sbjct: 897 TFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPG 946
Score = 31.6 bits (70), Expect = 0.91
Identities = 15/47 (31%), Positives = 23/47 (48%)
Frame = +3
Query: 117 LCHAAIAGRTCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRG 257
L + A + CP P PF + S Y+ G+ + + C PGY+ G
Sbjct: 2079 LAYQAYELQNCPDPP--PFQNGYMINSDYSVGQSVSFECYPGYILIG 2123
Score = 30.8 bits (68), Expect = 1.6
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Frame = +3
Query: 762 DKATYGCHDTYTLDGPEEVECNKFGN--WSAQ-PSCKASCKLSVK 887
D T+ C Y L+G ++ C G WSA P C A C SVK
Sbjct: 1066 DSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVK 1110
Score = 30.4 bits (67), Expect = 2.0
Identities = 15/53 (28%), Positives = 25/53 (46%), Gaps = 3/53 (5%)
Frame = +3
Query: 330 CPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGK---WSPD 479
C G+ +NG + E +T++F C+ G+ L+G C + W PD
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPD 1444
Score = 29.6 bits (65), Expect = 3.5
Identities = 14/48 (29%), Positives = 22/48 (45%)
Frame = +3
Query: 330 CPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWS 473
C GI G ++F + +T++F C F L G C + +WS
Sbjct: 528 CGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWS 575
>gi|4504375|ref|NP_000177.1| (NM_000186) H factor 1 (complement); H
factor-1 (complement) [Homo sapiens]
Length = 1231
Score = 81.3 bits (199), Expect = 1e-15
Identities = 63/255 (24%), Positives = 97/255 (37%), Gaps = 7/255 (2%)
Frame = +3
Query: 138 GRTCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKC 317
G C P E+ VV + SY GEE+ Y C G+ G I G + C
Sbjct: 928 GLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPA---IAKCLGEKWSHPPSC 984
Query: 318 LPRVCPFAGILENG---AVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWS--PDL 482
+ C EN + ++ +++TC + + GA++ C +W+ P
Sbjct: 985 IKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCI-NSRWTGRPTC 1043
Query: 483 XXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNW 662
+ K +G Y +C + MFG+ + C +GNW
Sbjct: 1044 RDTSCVNPPTVQNAYIVSRQMSKYPSGERVRY------QCRSPYEMFGDEEVMCL-NGNW 1096
Query: 663 TELPECKEV--KCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFG 836
TE P+CK+ KC P +NG + V Y C + Y L+G + + C G
Sbjct: 1097 TEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRN-G 1155
Query: 837 NWSAQPSCKASCKLS 881
WS P C C +S
Sbjct: 1156 QWSEPPKCLHPCVIS 1170
Score = 74.7 bits (182), Expect = 9e-14
Identities = 66/256 (25%), Positives = 96/256 (36%), Gaps = 16/256 (6%)
Frame = +3
Query: 141 RTCPKPEELPFAVVVPLKSS-YAPGEEIVYTCQPGYVSRGGIRRFICPLTGLW----PI- 302
R C P + PF + + G + VYTC GY G I C G W PI
Sbjct: 83 RPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPIC 141
Query: 303 NTLKCLPRVCPFAGILENGAVRYTT-FEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPD 479
+KCLP P G + + A+ + + + F CN G+ ++G C+++G WS +
Sbjct: 142 EVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKE 201
Query: 480 LXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAV--------FECLPQHAMFGNGT 635
K ++S P N S K + ++C + G
Sbjct: 202 -------------KPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGD 248
Query: 636 ITCTEHGNWTELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHD-TYTLDGPE 812
CTE G W LP C+E C P P + P + D+ TY C + Y
Sbjct: 249 AVCTESG-WRPLPSCEEKSCDNPYIPNGDY--SPLRIKHRTGDEITYQCRNGFYPATRGN 305
Query: 813 EVECNKFGNWSAQPSC 860
+C G W P C
Sbjct: 306 TAKCTSTG-WIPAPRC 320
Score = 72.8 bits (177), Expect = 4e-13
Identities = 64/231 (27%), Positives = 100/231 (42%), Gaps = 9/231 (3%)
Frame = +3
Query: 198 SYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTL-KCLPRVCPFAGILENGAVRYT 374
+Y G + +Y C+PGY S G + +C +N L KC R C G G T
Sbjct: 41 TYPEGTQAIYKCRPGYRSLGNV-IMVCRKGEWVALNPLRKCQKRPCGHPGDTPFGTFTLT 99
Query: 375 ---TFEYPNTISFTCNRGFSLKG-ANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLS 542
FEY +TCN G+ L G N +C +G W+ D+ + K+
Sbjct: 100 GGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKI- 157
Query: 543 VYKPLAGNNSLYGGKAV-FECLPQHAMFGNGTITCTEHGNWT-ELPECKEVKCPFPSRPE 716
V + + + G+AV F C + + G+ + C++ G W+ E P+C E+ C P
Sbjct: 158 VSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPD-VI 216
Query: 717 NGFVNYPAKQVLYYQ--DKATYGCHDTYTLDGPEEVECNKFGNWSAQPSCK 863
NG P Q + Y+ ++ Y C+ Y + C + G W PSC+
Sbjct: 217 NG---SPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WRPLPSCE 263
Score = 69.3 bits (168), Expect = 4e-12
Identities = 72/265 (27%), Positives = 106/265 (39%), Gaps = 17/265 (6%)
Frame = +3
Query: 141 RTCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGY--VSRGGIRRFICPLTGLWPINTLK 314
++C P +P PL+ + G+EI Y C+ G+ +RG + C TG P +
Sbjct: 265 KSCDNPY-IPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAK--CTSTGWIPAP--R 319
Query: 315 CLPRVCPFAGILENGAVR------YTTFEYPNTISFTCNRGFSLKGAN---SAKCTEEGK 467
C + C + I G Y S+ C+ F + CT++G
Sbjct: 320 CTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG- 378
Query: 468 WSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAM-FGNGTITC 644
WSP + Y G + G C P +A+ T+TC
Sbjct: 379 WSPAVPCLRKCYFPYLENG-------YNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTC 431
Query: 645 TEHGNWTELPECKEVKCPFPSRP--ENGFVNYPAKQVLYYQDKATYGCHDTY-TLDGPEE 815
E+G W+ P C VK S ENGF++ ++ ++KA Y C Y T DG
Sbjct: 432 MENG-WSPTPRCIRVKTCSKSSIDIENGFIS-ESQYTYALKEKAKYQCKLGYVTADGETS 489
Query: 816 --VECNKFGNWSAQPSCKASCKLSV 884
+ C K G WSAQP+C SC + V
Sbjct: 490 GSIRCGKDG-WSAQPTCIKSCDIPV 513
Score = 68.6 bits (166), Expect = 7e-12
Identities = 66/279 (23%), Positives = 108/279 (38%), Gaps = 18/279 (6%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPR 326
CP P ++P + + +Y GE++ CQ Y+ + G C G W L C+ +
Sbjct: 811 CPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEG-EEITCK-DGRWQSIPL-CVEK 867
Query: 327 V-CPFAGILENGAVRYT-----TFEYPNTISFTCNRGFSLKGANSAKCTEEGKWS--PDL 482
+ C +E+G + + ++ + +S+TC GF + N C GKWS P
Sbjct: 868 IPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTC-YMGKWSSPPQC 926
Query: 483 XXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNW 662
A +S ++ YG + ++C + G C W
Sbjct: 927 EGLPCKSPPEISHGVVAHMS-------DSYQYGEEVTYKCFEGFGIDGPAIAKCLGE-KW 978
Query: 663 TELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNW 842
+ P C + C EN K V ++ TY C Y +DG V C W
Sbjct: 979 SHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCIN-SRW 1037
Query: 843 SAQPSCK-ASC--KLSVKRATVIY-------EGERVNIQ 929
+ +P+C+ SC +V+ A ++ GERV Q
Sbjct: 1038 TGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQ 1076
Score = 64.7 bits (156), Expect = 1e-10
Identities = 71/277 (25%), Positives = 108/277 (38%), Gaps = 12/277 (4%)
Frame = +3
Query: 144 TCPKPEELPFAVVVPLKSSYA---PGEEIVYTCQPGYVSRGGIRR--FICPLTGLWPINT 308
TC K ++P + K+ + + + Y C GY S G +C G W
Sbjct: 504 TCIKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNG-WSDLP 562
Query: 309 LKCLPRVCPFAGILENGAVRYTTFEYP--NTISFTCNRGFSLKGANSAKCTEEGKWSPDL 482
+ C R C I + +Y + F+C GF++ G NS +C G SPDL
Sbjct: 563 I-CYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDL 620
Query: 483 XXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFE--CLPQHAMFGNGTITCTEHG 656
+ +V + YG V E C P+ M G I C + G
Sbjct: 621 PICKEQVQSCGPPPELLNGNVKEK---TKEEYGHSEVVEYYCNPRFLMKGPNKIQCVD-G 676
Query: 657 NWTELPEC--KEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNK 830
WT LP C +E C E+G+ + YY D + C +++T+ G + C
Sbjct: 677 EWTTLPVCIVEESTCGDIPELEHGWAQLSSPPY-YYGDSVEFNCSESFTMIGHRSITC-I 734
Query: 831 FGNWSAQPSCKASCKL-SVKRATVIYEGERVNIQDKF 938
G W+ P C A KL K + +I E + + +F
Sbjct: 735 HGVWTQLPQCVAIDKLKKCKSSNLIILEEHLKNKKEF 771
Score = 52.0 bits (123), Expect = 7e-07
Identities = 62/255 (24%), Positives = 100/255 (38%), Gaps = 15/255 (5%)
Frame = +3
Query: 141 RTCPKPE-ELPFAVVVPLKSSYAPGEEIVYTCQPGYVSR-----GGIRRFICPLTGLWPI 302
+TC K ++ + + +YA E+ Y C+ GYV+ G IR C G W
Sbjct: 446 KTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSIR---CGKDG-WSA 501
Query: 303 NTLKCLPRVCPFAGILENGAVR--YTTFEYPNTISFTCNRGFSLKGAN---SAKCTEEGK 467
C+ + C + N + +T F+ +T+ + C+ G+ + S C G
Sbjct: 502 QPT-CI-KSCDIP-VFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNG- 557
Query: 468 WSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLY--GGKAVFECLPQHAMFGNGTIT 641
WS DL + K+ V+ Y G F C P + G ++
Sbjct: 558 WS-DLPICYEREC------ELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQ 610
Query: 642 CTEHGNWTELPECKE--VKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEE 815
C G +LP CKE C P NG V K+ + + Y C+ + + GP +
Sbjct: 611 CYHFGLSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNK 670
Query: 816 VECNKFGNWSAQPSC 860
++C G W+ P C
Sbjct: 671 IQCVD-GEWTTLPVC 684
Score = 47.4 bits (111), Expect = 2e-05
Identities = 56/240 (23%), Positives = 88/240 (36%), Gaps = 19/240 (7%)
Frame = +3
Query: 201 YAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLP-RVCPFAGI-LENGAVRYT 374
+ G+ I C PGY C G P T +C+ + C + I +ENG + +
Sbjct: 406 FVQGKSIDVACHPGYALPKAQTTVTCMENGWSP--TPRCIRVKTCSKSSIDIENGFISES 463
Query: 375 TFEYP--NTISFTCNRGFSL---KGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKL 539
+ Y + C G+ + + S +C ++G WS K +
Sbjct: 464 QYTYALKEKAKYQCKLGYVTADGETSGSIRCGKDG-WSAQ-----------PTCIKSCDI 511
Query: 540 SVYKPLAGNNSLYGGKAV----FEC---LPQHAMFGNGTITCTEHGNWTELPECKEVKCP 698
V+ N K +EC + G+I C +G W++LP C E +C
Sbjct: 512 PVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNG-WSDLPICYERECE 570
Query: 699 FPSR-----PENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQPSCK 863
P P+ Y +VL + C +T+ GP V+C FG P CK
Sbjct: 571 LPKIDVHLVPDRKKDQYKVGEVL------KFSCKPGFTIVGPNSVQCYHFGLSPDLPICK 624
>gi|11321587|ref|NP_002104.1| (NM_002113) H factor (complement)-like
1 [Homo sapiens]
Length = 330
Score = 80.5 bits (197), Expect = 2e-15
Identities = 68/236 (28%), Positives = 102/236 (42%), Gaps = 7/236 (2%)
Frame = +3
Query: 195 SSYAPGEEIVYTCQPGYVS--RGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVR 368
S GE Y+C+ +VS + R C G P T KCL R+C F +ENG
Sbjct: 43 SQVPTGEVFYYSCEYNFVSPSKSFWTRITCTEEGWSP--TPKCL-RLC-FFPFVENGHSE 98
Query: 369 YT--TFEYPNTISFTCNRGFSLKG-ANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKL 539
+ T +T+ CN G+ L+ N+ C E G +P + A +
Sbjct: 99 SSGQTHLEGDTVQIICNTGYRLQNNENNISCVERGWSTPPKCRSTDTSCVNPPTVQNAYI 158
Query: 540 SVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTELPECKEV--KCPFPSRP 713
V + ++ S G + ++C + MFG+ + C +GNWTE P+CK+ KC P
Sbjct: 159 -VSRQMSKYPS--GERVRYQCRSPYEMFGDEEVMCL-NGNWTEPPQCKDSTGKCGPPPPI 214
Query: 714 ENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQPSCKASCKLS 881
+NG + V Y C + Y L+G + + C G WS P C C +S
Sbjct: 215 DNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRN-GQWSEPPKCLHPCVIS 269
>gi|10834974|ref|NP_000564.1| (NM_000573) complement component (3b/4b)
receptor-1 isoform F precursor; complement component
(3b/4b) receptor-1; C3-binding protein; CD35 antigen
[Homo sapiens]
Length = 2039
Score = 79.0 bits (193), Expect = 5e-15
Identities = 70/241 (29%), Positives = 98/241 (40%), Gaps = 19/241 (7%)
Frame = +3
Query: 177 VVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTG---LWPINTLKCLPRVCPFAGI 347
V++PL G ++ + C G+ +G C L G LW + C CP
Sbjct: 1723 VLLPLNLQL--GAKVSFVCDEGFRLKGRSASH-CVLAGMKALWNSSVPVCEQIFCPNPPA 1779
Query: 348 LENGAVRYTTF---EYPNTISFTCN----RG--FSLKGANSAKCTEE----GKWSPDLXX 488
+ NG T F Y IS+ C+ RG F+L G +S +CT + G WS
Sbjct: 1780 ILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPR 1839
Query: 489 XXXXXXXXXXXXKFAKLSVYKPLAGNNSLY--GGKAVFECLPQHAMFGNGTITCTEHGNW 662
+ Y + G+ SLY G + C P + + G G I CT+ G W
Sbjct: 1840 CELSVPAACPHPPKIQNGHY--IGGHVSLYLPGMTISYTCDPGYLLVGKGFIFCTDQGIW 1897
Query: 663 TELPE-CKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGN 839
++L CKEV C FP K+V +Y D T C D YTL+G +C
Sbjct: 1898 SQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDR 1957
Query: 840 W 842
W
Sbjct: 1958 W 1958
Score = 68.9 bits (167), Expect = 5e-12
Identities = 64/273 (23%), Positives = 100/273 (36%), Gaps = 25/273 (9%)
Frame = +3
Query: 132 IAGRTCPKPEELPFAVVVPLKSSYA--PGEEIVYTCQPGYVSRGGIRRFICPLTGLWPIN 305
+A C PE LPFA L + G + Y C+PGY R IC +W
Sbjct: 38 VAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRPF--SIICLKNSVWTGA 95
Query: 306 TLKCLPRVCPFAGILENGAVRYTT-FEYPNTISFTCNRGFSLKGANSAKCTEEGK---WS 473
+C + C NG V ++ + I ++C +G+ L G++SA C G W
Sbjct: 96 KDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWD 155
Query: 474 -------------PDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQH 614
P + + Y+ G+ GG+ VFE
Sbjct: 156 NETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS----GGRKVFE----- 206
Query: 615 AMFGNGTITCTEH----GNWT-ELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYG 779
+ G +I CT + G W+ P+C P ENG + + + + +
Sbjct: 207 -LVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFR 265
Query: 780 CHDTYTLDGPEEVECNKFGNWSAQ-PSCKASCK 875
C + + GP V+C W + PSC C+
Sbjct: 266 CQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQ 298
Score = 66.6 bits (161), Expect = 3e-11
Identities = 67/261 (25%), Positives = 98/261 (36%), Gaps = 18/261 (6%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPR 326
C P +V +S ++ E + + CQPG+V +G RR C W C R
Sbjct: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP-RRVKCQALNKWEPELPSC-SR 1195
Query: 327 VC-PFAGIL--ENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXX 497
VC P IL E+ F + ++C G+ L+GA S CT +G WSP+
Sbjct: 1196 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAV 1255
Query: 498 XXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGN---W-T 665
+L + L N G K F C + G+ C G W
Sbjct: 1256 KSCDDF----LGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNN 1311
Query: 666 ELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHD------TYTLDGPEEVECN 827
+P C+ + CP P NG + Y + +Y C T+ L G + C
Sbjct: 1312 SVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCT 1371
Query: 828 K----FGNWSA-QPSCKASCK 875
G WS+ P C+ S +
Sbjct: 1372 SDPHGNGVWSSPAPRCELSVR 1392
Score = 65.5 bits (158), Expect = 6e-11
Identities = 67/257 (26%), Positives = 100/257 (38%), Gaps = 22/257 (8%)
Frame = +3
Query: 141 RTC-PKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKC 317
R C P PE L + + +++PG+E+ Y+C+P Y RG P G W +C
Sbjct: 1648 RVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTP-QGDWSPEAPRC 1706
Query: 318 LPRVCP-FAGILENGAVRYT-TFEYPNTISFTCNRGFSLKGANSAKCTEEGK---WSPDL 482
+ C F G L +G V + +SF C+ GF LKG +++ C G W+ +
Sbjct: 1707 TVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSV 1766
Query: 483 XXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFEC--LPQHAM----FGNGTITC 644
+ + + YG + + C P M G +I C
Sbjct: 1767 PVCEQIFCPNPPAILNGR---HTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRC 1823
Query: 645 TE----HGNWTE-LPECK---EVKCPFPSRPENGFVNYPAKQVLYYQDKAT--YGCHDTY 794
T +G W+ P C+ CP P + +NG +Y V Y T Y C Y
Sbjct: 1824 TSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNG--HYIGGHVSLYLPGMTISYTCDPGY 1881
Query: 795 TLDGPEEVECNKFGNWS 845
L G + C G WS
Sbjct: 1882 LLVGKGFIFCTDQGIWS 1898
Score = 64.3 bits (155), Expect = 1e-10
Identities = 72/282 (25%), Positives = 104/282 (36%), Gaps = 19/282 (6%)
Frame = +3
Query: 132 IAGRTCPKPEELPFAVVVPLKSSYAPGEEIV-YTCQPGYVSRGGIRRFICPLTGLWPINT 308
I+ C PE + A+ VP S+ EI+ + CQPG+V G C G W
Sbjct: 1586 ISTNKCTAPE-VENAIRVPGNRSFFSLTEIIRFRCQPGFVMVGS-HTVQCQTNGRWGPKL 1643
Query: 309 LKCLPRVC-PFAGIL--ENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPD 479
C RVC P IL E+ F + ++C + L+GA S CT +G WSP+
Sbjct: 1644 PHC-SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPE 1702
Query: 480 LXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGN 659
+L + L N G K F C + G C G
Sbjct: 1703 APRCTVKSCDDF----LGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGM 1758
Query: 660 ---W-TELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHD------TYTLDGP 809
W + +P C+++ CP P NG + Y + +Y C T+ L G
Sbjct: 1759 KALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGE 1818
Query: 810 EEVECNK----FGNWSA-QPSCKASCKLSVKRATVIYEGERV 920
+ C G WS+ P C+ S + I G +
Sbjct: 1819 SSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYI 1860
Score = 62.4 bits (150), Expect = 5e-10
Identities = 64/256 (25%), Positives = 95/256 (37%), Gaps = 18/256 (7%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPR 326
C P +V +S ++ E + + CQPG+V +G RR C W C R
Sbjct: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP-RRVKCQALNKWEPELPSC-SR 745
Query: 327 VC-PFAGIL--ENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXX 497
VC P +L E F + ++C G+ L+GA S +CT +G WSP
Sbjct: 746 VCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSP----AAP 801
Query: 498 XXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGN---W-T 665
+L + L N G K F C + G+ C G W +
Sbjct: 802 TCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNS 861
Query: 666 ELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCH------DTYTLDGPEEVECN 827
+P C+++ CP P NG +V + Y C ++ L G + C
Sbjct: 862 SVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCT 921
Query: 828 K----FGNWSA-QPSC 860
G WS+ P C
Sbjct: 922 SDPQGNGVWSSPAPRC 937
Score = 62.4 bits (150), Expect = 5e-10
Identities = 64/256 (25%), Positives = 95/256 (37%), Gaps = 18/256 (7%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPR 326
C P +V +S ++ E + + CQPG+V +G RR C W C R
Sbjct: 238 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP-RRVKCQALNKWEPELPSC-SR 295
Query: 327 VC-PFAGIL--ENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXX 497
VC P +L E F + ++C G+ L+GA S +CT +G WSP
Sbjct: 296 VCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSP----AAP 351
Query: 498 XXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGN---W-T 665
+L + L N G K F C + G+ C G W +
Sbjct: 352 TCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNS 411
Query: 666 ELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCH------DTYTLDGPEEVECN 827
+P C+++ CP P NG +V + Y C ++ L G + C
Sbjct: 412 SVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCT 471
Query: 828 K----FGNWSA-QPSC 860
G WS+ P C
Sbjct: 472 SDPQGNGVWSSPAPRC 487
Score = 57.8 bits (138), Expect = 1e-08
Identities = 60/268 (22%), Positives = 94/268 (34%), Gaps = 25/268 (9%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLK--SSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCL 320
C P+ FA + S + G + Y C+P Y R C +W C
Sbjct: 493 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPF--SITCLDNLVWSSPKDVCK 550
Query: 321 PRVCPFAGILENGAVRYTT-FEYPNTISFTCNRGFSLKGANSAKCTEEGK---WS----- 473
+ C NG V T + + I+++C G L G +SA+C G WS
Sbjct: 551 RKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPI 610
Query: 474 --------PDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGN 629
P + + Y+ G+ GG+ VFE + G
Sbjct: 611 CQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGS----GGRKVFE------LVGE 660
Query: 630 GTITCTEH----GNWT-ELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTY 794
+I CT + G W+ P+C P ENG + + + + + C +
Sbjct: 661 PSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGF 720
Query: 795 TLDGPEEVECNKFGNWSAQ-PSCKASCK 875
+ GP V+C W + PSC C+
Sbjct: 721 VMKGPRRVKCQALNKWEPELPSCSRVCQ 748
Score = 55.5 bits (132), Expect = 6e-08
Identities = 59/268 (22%), Positives = 93/268 (34%), Gaps = 25/268 (9%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLK--SSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCL 320
C P+ FA + S + G + Y C+P Y R C +W C
Sbjct: 943 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPF--SITCLDNLVWSSPKDVCK 1000
Query: 321 PRVCPFAGILENGAVRYTT-FEYPNTISFTCNRGFSLKGANSAKCTEEGK---WS----- 473
+ C NG V T + + I+++C G L G +SA+C G WS
Sbjct: 1001 RKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPI 1060
Query: 474 --------PDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGN 629
P + + Y+ G+ G+ VFE + G
Sbjct: 1061 CQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSR----GRKVFE------LVGE 1110
Query: 630 GTITCTEH----GNWT-ELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTY 794
+I CT + G W+ P+C P ENG + + + + + C +
Sbjct: 1111 PSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGF 1170
Query: 795 TLDGPEEVECNKFGNWSAQ-PSCKASCK 875
+ GP V+C W + PSC C+
Sbjct: 1171 VMKGPRRVKCQALNKWEPELPSCSRVCQ 1198
Score = 55.5 bits (132), Expect = 6e-08
Identities = 64/279 (22%), Positives = 101/279 (35%), Gaps = 27/279 (9%)
Frame = +3
Query: 120 CHAAIAGRTCPKPEELPFAV-VVPLKSSYAP-GEEIVYTCQPGYVSRGGIRRFICPLTGL 293
C ++ C PE+ PFA +P+ P G + Y C+PGY G + C +
Sbjct: 1387 CELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF--GKMFSISCLENLV 1444
Query: 294 WPINTLKCLPRVCPFAGILENGAVRYTT-FEYPNTISFTCNRGFSLKGANSAKCTEEGK- 467
W C + C NG V T ++ +T++++CN GF L G+ S C G
Sbjct: 1445 WSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNN 1504
Query: 468 --WS-------------PDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFEC 602
W P + Y+ G + G+ +FE
Sbjct: 1505 VTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPD----GEQLFE- 1559
Query: 603 LPQHAMFGNGTITCT----EHGNWTE-LPECKEV-KCPFPSRPENGFVNYPAKQVLY-YQ 761
+ G +I CT + G W+ P C KC P EN + P + +
Sbjct: 1560 -----LVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAP-EVENA-IRVPGNRSFFSLT 1612
Query: 762 DKATYGCHDTYTLDGPEEVECNKFGNWSAQ-PSCKASCK 875
+ + C + + G V+C G W + P C C+
Sbjct: 1613 EIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQ 1651
Database: RefSeq (Homo Sapiens/Amino Acid)
Posted date: Jul 1, 2003 6:07 AM
Number of letters in database: 10,046,356
Number of sequences in database: 19,244
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21920042
Number of Sequences: 19244
Number of extensions: 582358
Number of successful extensions: 2446
Number of sequences better than 10.0: 85
Number of HSP's better than 10.0 without gapping: 1264
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 375
Number of HSP's gapped (non-prelim): 1750
length of query: 334
length of database: 10,046,356
effective HSP length: 47
effective length of query: 287
effective length of database: 9,141,888
effective search space: 2623721856
effective search space used: 2623721856
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search to RefSeq (Mouse) database
Query= 20030531C-000211 (20030531C-000211) 20030531C-000211
(1004 letters)
Database: RefSeq (Mus Musculus/Amino Acid)
15,330 sequences; 7,155,815 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|7304899|ref|NP_038503.1| (NM_013475) apolipoprotein H; beta-... 432 e-123
Alignment gi|12738842|ref|NP_073725.1| (NM_022814) polydomain protein; D4... 98 7e-21
Alignment gi|6755452|ref|NP_035475.1| (NM_011345) selectin, endothelial c... 89 3e-18
Alignment gi|6755456|ref|NP_035477.1| (NM_011347) selectin, platelet; P s... 86 2e-17
Alignment gi|16716457|ref|NP_444401.1| (NM_053171) CUB and Sushi multiple... 82 4e-16
Alignment gi|31542275|ref|NP_031602.2| (NM_007576) complement component 4... 81 9e-16
Alignment gi|13624321|ref|NP_112441.1| (NM_031164) coagulation factor XII... 81 9e-16
Alignment gi|19072788|ref|NP_034018.1| (NM_009888) complement component f... 81 9e-16
Alignment gi|6677655|ref|NP_033607.1| (NM_009581) zona pellucida 3 recept... 75 7e-14
Alignment gi|7656969|ref|NP_056595.1| (NM_015780) complement factor H-rel... 70 1e-12
>gi|7304899|ref|NP_038503.1| (NM_013475) apolipoprotein H;
beta-2-glycoprotein 1 [Mus musculus]
Length = 345
Score = 432 bits (1111), Expect(2) = e-123
Identities = 195/287 (67%), Positives = 225/287 (77%)
Frame = +3
Query: 81 MIPPVLIFFLSFLCHAAIAGRTCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGG 260
M+ PVL F +FLCH AIAGR CPKP++LPFA VVPLK+SY PGE+IVY+C+PGYVSRGG
Sbjct: 1 MVSPVLALFSAFLCHVAIAGRICPKPDDLPFATVVPLKTSYDPGEQIVYSCKPGYVSRGG 60
Query: 261 IRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGAN 440
+RRF CPLTG+WPINTL+C+PRVCPFAGILENG VRYT+FEYP ISF CN GF L G +
Sbjct: 61 MRRFTCPLTGMWPINTLRCVPRVCPFAGILENGIVRYTSFEYPKNISFACNPGFFLNGTS 120
Query: 441 SAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAM 620
S+KCTEEGKWSPD+ KFA L Y+P AGNNSLY VF+CLP AM
Sbjct: 121 SSKCTEEGKWSPDIPACARITCPPPPVPKFALLKDYRPSAGNNSLYQDTVVFKCLPHFAM 180
Query: 621 FGNGTITCTEHGNWTELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTL 800
GN T+ CTE GNWT LPEC EVKCPFP RPENG+VNYPAK VL Y+DKAT+GCH+TY L
Sbjct: 181 IGNDTVMCTEQGNWTRLPECLEVKCPFPPRPENGYVNYPAKPVLLYKDKATFGCHETYKL 240
Query: 801 DGPEEVECNKFGNWSAQPSCKASCKLSVKRATVIYEGERVNIQDKFK 941
DGPEE EC K WS P+C+ SCKL VK+ATV+Y+G RV IQ++FK
Sbjct: 241 DGPEEAECTKTRTWSFLPTCRESCKLPVKKATVLYQGMRVKIQEQFK 287
Score = 26.6 bits (57), Expect(2) = e-123
Identities = 10/12 (83%), Positives = 11/12 (91%)
Frame = +2
Query: 965 KISFFCKNKEKK 1000
KI F+CKNKEKK
Sbjct: 295 KIHFYCKNKEKK 306
>gi|12738842|ref|NP_073725.1| (NM_022814) polydomain protein;
D430029O09Rik [Mus musculus]
Length = 3567
Score = 97.8 bits (242), Expect = 7e-21
Identities = 77/266 (28%), Positives = 105/266 (38%), Gaps = 15/266 (5%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPR 326
C PE VV K S+ G IVY C PGY G R IC W C
Sbjct: 3237 CGHPESPAHGSVVGNKHSF--GSTIVYQCDPGYKLEGNRER-ICQENRQWSGEVAVCREN 3293
Query: 327 VCPFAGILENG-AVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXX 503
C NG AV T P+ + F+C+RG++L+G+ A CT G W+
Sbjct: 3294 RCETPAEFPNGKAVLENTTSGPSLL-FSCHRGYTLEGSPEAHCTANGTWN---------- 3342
Query: 504 XXXXXXXKFAKLSVYKP-----LAGNNSLYGGKAVF-------ECLPQHAMFGNGTITCT 647
L P + N++ K + +C + GNG ITC+
Sbjct: 3343 -------HLTPLCKPNPCPVPFVIPENAVLSEKEFYVDQNVSIKCREGFLLKGNGVITCS 3395
Query: 648 EHGNWTEL-PECKEVKCPFPSRPENGFVNYPAKQVLY-YQDKATYGCHDTYTLDGPEEVE 821
WT C+++ C PS EN A+ V Y Y D TY C+ Y L+G
Sbjct: 3396 PDETWTHTNARCEKISCGPPSHVENAI----ARGVYYQYGDMITYSCYSGYMLEGSLRSV 3451
Query: 822 CNKFGNWSAQPSCKASCKLSVKRATV 899
C + G W+ P C+A C+ + V
Sbjct: 3452 CLENGTWTPSPVCRAVCRFPCQNGGV 3477
Score = 93.2 bits (230), Expect = 2e-19
Identities = 65/245 (26%), Positives = 94/245 (37%), Gaps = 5/245 (2%)
Frame = +3
Query: 144 TCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLP 323
+C P + AV +Y ++ C GYV F C G W + C P
Sbjct: 3117 SCGPPPTVANAVATGEAHTYE--SKVKLRCLEGYVMDSDTDTFTCQQDGHWVPERITCSP 3174
Query: 324 RVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXX 503
+ CP + F+ +S +C GF+ +G N + C +G W P
Sbjct: 3175 KKCPVPSNMTRIRFHGDDFQVNRQVSVSCAEGFTHEGVNWSTCQPDGTWEPPFSDESCIP 3234
Query: 504 XXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPEC 680
A SV GN +G V++C P + + GN C E+ W+ E+ C
Sbjct: 3235 VVCGHPESPAHGSV----VGNKHSFGSTIVYQCDPGYKLEGNRERICQENRQWSGEVAVC 3290
Query: 681 KEVKCPFPSRPENGFVNYPAKQVLYYQDKA---TYGCHDTYTLDGPEEVECNKFGNWS-A 848
+E +C P+ NG K VL + CH YTL+G E C G W+
Sbjct: 3291 RENRCETPAEFPNG------KAVLENTTSGPSLLFSCHRGYTLEGSPEAHCTANGTWNHL 3344
Query: 849 QPSCK 863
P CK
Sbjct: 3345 TPLCK 3349
Score = 89.4 bits (220), Expect = 3e-18
Identities = 71/263 (26%), Positives = 93/263 (34%), Gaps = 37/263 (14%)
Frame = +3
Query: 186 PLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAV 365
P + PG ++ C PG+ G ++ C G W C C LENG
Sbjct: 1642 PASGNRKPGSKVSLFCDPGFQMVGNPVQY-CLNQGQWTQPLPHCERIRCGLPPALENGFY 1700
Query: 366 RYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKW---SPDLXXXXXXXXXXXXXXKFAK 536
F +T+++ C G+ L G + CT+ G W SP +
Sbjct: 1701 SAEDFHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASC 1760
Query: 537 L--------SVYKPLAGNNS------------------------LYGGKAVFECLPQHAM 620
L S P G+ G F C H +
Sbjct: 1761 LNTNGSYVCSCNPPYTGDGKNCAEPVKCKAPENPENGHSSGEIYTVGTAVTFSCDEGHEL 1820
Query: 621 FGNGTITCTEHGNWTEL-PECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYT 797
G TITC E G W L P C+ + C P PENG V+ A Y K Y C YT
Sbjct: 1821 VGVSTITCLETGEWDRLRPSCEAISCGVPPVPENGGVDGSA---FTYGSKVVYRCDKGYT 1877
Query: 798 LDGPEEVECNKFGNWS-AQPSCK 863
L G EE C G+WS + P C+
Sbjct: 1878 LSGDEESACLASGSWSHSSPVCE 1900
Score = 84.3 bits (207), Expect = 8e-17
Identities = 62/231 (26%), Positives = 95/231 (40%), Gaps = 9/231 (3%)
Frame = +3
Query: 195 SSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYT 374
S + G + Y+C+PGY G I IC G W C+ C ENG + +T
Sbjct: 2670 SHFLYGTMVSYSCEPGYELLG-IPVLICQEDGTWNGTAPSCISIECDLPVAPENGFLHFT 2728
Query: 375 TFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKP 554
+ ++C G L+G++ C + +WS + +S KP
Sbjct: 2729 QTTMGSAAQYSCKPGHILEGSHLRLCLQNKQWS-------------GTVPRCEAISCSKP 2775
Query: 555 -------LAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPECKEVKCPFPSR 710
+ G++ Y G +EC + + G+ TC E+ +W P C V C P
Sbjct: 2776 NPLWNGSIKGDDYSYLGVLYYECDSGYILNGSKKRTCQENRDWDGHEPMCIPVDCGSPPV 2835
Query: 711 PENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWS-AQPSC 860
P NG V + +Q + TY C + + L+G C G+WS A PSC
Sbjct: 2836 PTNGRVK---GEEYTFQKEITYSCREGFILEGARSRICLTNGSWSGATPSC 2883
Score = 84.3 bits (207), Expect = 8e-17
Identities = 59/230 (25%), Positives = 90/230 (38%), Gaps = 6/230 (2%)
Frame = +3
Query: 195 SSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYT 374
S++ G ++VY C GY G C +G W ++ C C + NG +
Sbjct: 1860 SAFTYGSKVVYRCDKGYTLSGD-EESACLASGSWSHSSPVCELVKCSQPEDINNGKYILS 1918
Query: 375 TFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKP 554
Y + S++C G+SL+G + +CT G W K A ++
Sbjct: 1919 GLTYLSIASYSCENGYSLQGPSLLECTASGSWDRAPPSCQLVSCGEPPIVKDAVIT---- 1974
Query: 555 LAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTELP-ECKEVKCPFPSRPENGFVN 731
G+N +G + C + + G TI C +G W +C V C P ++
Sbjct: 1975 --GSNFTFGNTVAYTCKEGYTLAGPDTIVCQANGKWNSSNHQCLAVSCDEPPNVDHAS-- 2030
Query: 732 YPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNW-----SAQPSCKA 866
P + D A Y C D Y+L ++ CN GNW A P C A
Sbjct: 2031 -PETAHRLFGDTAFYYCADGYSLADNSQLICNAQGNWVPPAGQAVPRCIA 2079
Score = 84.0 bits (206), Expect = 1e-16
Identities = 70/278 (25%), Positives = 106/278 (37%), Gaps = 15/278 (5%)
Frame = +3
Query: 144 TCPKPEELPFAVVVPLKSSYAPGEE------IVYTCQPGYVSRGGIRRFICPLTGLWPIN 305
T P+ E + + PL + G++ + Y C GY+ G +R C W +
Sbjct: 2763 TVPRCEAISCSKPNPLWNGSIKGDDYSYLGVLYYECDSGYILNGSKKR-TCQENRDWDGH 2821
Query: 306 TLKCLPRVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLX 485
C+P C + NG V+ + + I+++C GF L+GA S C G WS
Sbjct: 2822 EPMCIPVDCGSPPVPTNGRVKGEEYTFQKEITYSCREGFILEGARSRICLTNGSWS---- 2877
Query: 486 XXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGG-------KAVFECLPQHAMFGNGTITC 644
+ P N + G + F CL + + G +TC
Sbjct: 2878 ---------GATPSCMPVRCPAPPQVPNGVADGLDYGFKKEVAFHCLEGYVLQGAPRLTC 2928
Query: 645 TEHGNW-TELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVE 821
+G W E+P CK C P+ GF N + Y+ Y C Y L G
Sbjct: 2929 QSNGTWDAEVPVCKPATCGPPADLPQGFPNGFS---FYHGGHIQYQCFTGYKLHGNPSRR 2985
Query: 822 CNKFGNWS-AQPSCKASCKLSVKRATVIYEGERVNIQD 932
C G+WS + PSC L + +T I + +N D
Sbjct: 2986 CLPNGSWSGSSPSC-----LPCRCSTPIIQQGTINATD 3018
Score = 83.2 bits (204), Expect = 2e-16
Identities = 52/192 (27%), Positives = 78/192 (40%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPR 326
CP+PEE+ ++ +Y +YTC+PG+ G +C G W C P
Sbjct: 2439 CPQPEEILNGIIHVQGLAYL--STTLYTCKPGFELVGNATT-LCGENGQWLGGKPMCKPI 2495
Query: 327 VCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXX 506
CP + NG +F+Y TI++ C+RGF L+G S C E G W D
Sbjct: 2496 ECPEPKEILNGQFSSVSFQYGQTITYFCDRGFRLEGPKSLTCLETGDWDMDPPSCDAIHC 2555
Query: 507 XXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTELPECKE 686
+ + G + YG ++ C P + G+ TC E G + P C
Sbjct: 2556 SDPQPIENGFVE------GADYRYGAMIIYSCFPGFQVLGHAMQTCEESGWSSSSPTCVP 2609
Query: 687 VKCPFPSRPENG 722
+ C P + G
Sbjct: 2610 IDCGLPPHIDFG 2621
Score = 82.8 bits (203), Expect = 2e-16
Identities = 62/242 (25%), Positives = 92/242 (37%), Gaps = 4/242 (1%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPR 326
CP P +PF V + + G + Y C G+ RG +C W +C+P
Sbjct: 2380 CPSPPLIPFGVPASSGALHF-GSTVKYLCVDGFFLRGS-PTILCQADSTWSSPLPECVPV 2437
Query: 327 VCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKW---SPDLXXXXX 497
CP + NG + Y +T +TC GF L G + C E G+W P
Sbjct: 2438 ECPQPEEILNGIIHVQGLAYLSTTLYTCKPGFELVGNATTLCGENGQWLGGKPMCKPIEC 2497
Query: 498 XXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNW-TELP 674
+F+ +S YG + C + G ++TC E G+W + P
Sbjct: 2498 PEPKEILNGQFSSVSFQ---------YGQTITYFCDRGFRLEGPKSLTCLETGDWDMDPP 2548
Query: 675 ECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQP 854
C + C P ENGFV + Y Y C + + G C + G S+ P
Sbjct: 2549 SCDAIHCSDPQPIENGFVEGADYR---YGAMIIYSCFPGFQVLGHAMQTCEESGWSSSSP 2605
Query: 855 SC 860
+C
Sbjct: 2606 TC 2607
Score = 82.8 bits (203), Expect = 2e-16
Identities = 59/252 (23%), Positives = 106/252 (41%), Gaps = 13/252 (5%)
Frame = +3
Query: 147 CPKPEELPFAVVVPL-KSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTL--KC 317
C KP + ++++ + K+ +A G + + C G+V + C G W + L +C
Sbjct: 2082 CEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAK-IECLRGGEWSPSPLSVQC 2140
Query: 318 LPRVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXX 497
+P C + NG T + + ++++C++GF +KG + C G+WS
Sbjct: 2141 IPVRCGEPPSIANGYPSGTNYSFGAVVAYSCHKGFYIKGEKKSTCEATGQWSKPTPTCH- 2199
Query: 498 XXXXXXXXXKFAKLSVYKPLAGNNSL--------YGGKAVFECLPQHAMFGNGTITCTEH 653
+S +P N + +A F+C P + G+ C +
Sbjct: 2200 ------------PVSCNEPPKVENGFLEHTTGRTFESEARFQCNPGYKAAGSPVFVCQAN 2247
Query: 654 GNW-TELP-ECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECN 827
+W ++ P C + C P +NGF+ + +V K + C++ Y L G C
Sbjct: 2248 RHWHSDAPLSCTPLNCGKPPPIQNGFLKGESFEV---GSKVQFVCNEGYELVGDNSWTCQ 2304
Query: 828 KFGNWSAQPSCK 863
K G WS +PS K
Sbjct: 2305 KSGKWSKKPSPK 2316
Score = 82.8 bits (203), Expect = 2e-16
Identities = 63/218 (28%), Positives = 85/218 (38%), Gaps = 3/218 (1%)
Frame = +3
Query: 216 EIVYTCQPGYVSRGGIRRFICPLTGLWPINT-LKCLPRVCPFAGILENGAVRYTTFEYPN 392
E + C PGY + G F+C W + L C P C ++NG ++ +FE +
Sbjct: 2225 EARFQCNPGYKAAGS-PVFVCQANRHWHSDAPLSCTPLNCGKPPPIQNGFLKGESFEVGS 2283
Query: 393 TISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNS 572
+ F CN G+ L G NS C + GKWS +L V K LA
Sbjct: 2284 KVQFVCNEGYELVGDNSWTCQKSGKWSKKPSPKCVPTKCAEPPLLENQL-VLKELASE-- 2340
Query: 573 LYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPECKEVKCPFPSRPENGFVNYPAKQV 749
G C HA+ G + C G W P CK V CP P P F +
Sbjct: 2341 --VGVMTISCKEGHALQGPSVLKCLPSGQWNGSFPICKMVLCPSP--PLIPFGVPASSGA 2396
Query: 750 LYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQ-PSC 860
L++ Y C D + L G + C WS+ P C
Sbjct: 2397 LHFGSTVKYLCVDGFFLRGSPTILCQADSTWSSPLPEC 2434
Score = 79.7 bits (195), Expect = 2e-15
Identities = 60/239 (25%), Positives = 92/239 (38%), Gaps = 15/239 (6%)
Frame = +3
Query: 201 YAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYTTF 380
Y +EI Y+C+ G++ G R IC G W T C+P CP + NG +
Sbjct: 2846 YTFQKEITYSCREGFILEGARSR-ICLTNGSWSGATPSCMPVRCPAPPQVPNGVADGLDY 2904
Query: 381 EYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLA 560
+ ++F C G+ L+GA C G W A++ V KP
Sbjct: 2905 GFKKEVAFHCLEGYVLQGAPRLTCQSNGTWD-------------------AEVPVCKPAT 2945
Query: 561 -------------GNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPECKEVKCP 698
G + +GG ++C + + GN + C +G+W+ P C +C
Sbjct: 2946 CGPPADLPQGFPNGFSFYHGGHIQYQCFTGYKLHGNPSRRCLPNGSWSGSSPSCLPCRCS 3005
Query: 699 FPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQPSCK-ASC 872
P + G +N L C + L G E+ C+ G WS P C+ A C
Sbjct: 3006 TPI-IQQGTIN---ATDLGCGKTVQIECFKGFKLLGLSEITCDANGQWSDVPLCEHAQC 3060
Score = 77.4 bits (189), Expect = 1e-14
Identities = 55/232 (23%), Positives = 90/232 (38%), Gaps = 8/232 (3%)
Frame = +3
Query: 201 YAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYTTF 380
Y G + ++C G+ G+ C TG W C C + ENG V + F
Sbjct: 1804 YTVGTAVTFSCDEGH-ELVGVSTITCLETGEWDRLRPSCEAISCGVPPVPENGGVDGSAF 1862
Query: 381 EYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLA 560
Y + + + C++G++L G + C G WS + K S + +
Sbjct: 1863 TYGSKVVYRCDKGYTLSGDEESACLASGSWS-----------HSSPVCELVKCSQPEDIN 1911
Query: 561 GNNSLYGGK-----AVFECLPQHAMFGNGTITCTEHGNWTEL-PECKEVKCPFPSRPENG 722
+ G A + C +++ G + CT G+W P C+ V C P ++
Sbjct: 1912 NGKYILSGLTYLSIASYSCENGYSLQGPSLLECTASGSWDRAPPSCQLVSCGEPPIVKDA 1971
Query: 723 FVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNW-SAQPSCKA-SC 872
+ + + Y C + YTL GP+ + C G W S+ C A SC
Sbjct: 1972 VI---TGSNFTFGNTVAYTCKEGYTLAGPDTIVCQANGKWNSSNHQCLAVSC 2020
Score = 74.3 bits (181), Expect = 9e-14
Identities = 47/215 (21%), Positives = 82/215 (37%), Gaps = 5/215 (2%)
Frame = +3
Query: 225 YTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYTTFEYPNTISF 404
Y+C+ GY S G C +G W C C I+++ + + F + NT+++
Sbjct: 1928 YSCENGY-SLQGPSLLECTASGSWDRAPPSCQLVSCGEPPIVKDAVITGSNFTFGNTVAY 1986
Query: 405 TCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGG 584
TC G++L G ++ C GKW+ A + L+G
Sbjct: 1987 TCKEGYTLAGPDTIVCQANGKWNSSNHQCLAVSCDEPPNVDHASPETA------HRLFGD 2040
Query: 585 KAVFECLPQHAMFGNGTITCTEHGNWTE-----LPECKEVKCPFPSRPENGFVNYPAKQV 749
A + C +++ N + C GNW +P C C P + +K
Sbjct: 2041 TAFYYCADGYSLADNSQLICNAQGNWVPPAGQAVPRCIAHFCEKPPSVSYSILESVSKAK 2100
Query: 750 LYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQP 854
++ C + + L+ ++EC + G WS P
Sbjct: 2101 FAAGSVVSFKCMEGFVLNTSAKIECLRGGEWSPSP 2135
Score = 73.2 bits (178), Expect = 2e-13
Identities = 49/177 (27%), Positives = 73/177 (40%), Gaps = 3/177 (1%)
Frame = +3
Query: 351 ENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKF 530
ENG + ++F+C+ G L G ++ C E G+W
Sbjct: 1795 ENGHSSGEIYTVGTAVTFSCDEGHELVGVSTITCLETGEWD------RLRPSCEAISCGV 1848
Query: 531 AKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPECKEVKCPFPS 707
+ + G+ YG K V+ C + + G+ C G+W+ P C+ VKC P
Sbjct: 1849 PPVPENGGVDGSAFTYGSKVVYRCDKGYTLSGDEESACLASGSWSHSSPVCELVKCSQPE 1908
Query: 708 RPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWS-AQPSCK-ASC 872
NG L Y A+Y C + Y+L GP +EC G+W A PSC+ SC
Sbjct: 1909 DINNGKYILSG---LTYLSIASYSCENGYSLQGPSLLECTASGSWDRAPPSCQLVSC 1962
Score = 69.7 bits (169), Expect = 2e-12
Identities = 52/202 (25%), Positives = 76/202 (36%), Gaps = 8/202 (3%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPR 326
C P E P V ++ P ++++C GY G C G W T C P
Sbjct: 3295 CETPAEFPNGKAVLENTTSGPS--LLFSCHRGYTLEGSPEAH-CTANGTWNHLTPLCKPN 3351
Query: 327 VCPFAGIL-ENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXX 503
CP ++ EN + F +S C GF LKG C+ + W+
Sbjct: 3352 PCPVPFVIPENAVLSEKEFYVDQNVSIKCREGFLLKGNGVITCSPDETWT---------- 3401
Query: 504 XXXXXXXKFAKLSVYKPLAGNNSL-------YGGKAVFECLPQHAMFGNGTITCTEHGNW 662
+ K+S P N++ YG + C + + G+ C E+G W
Sbjct: 3402 ---HTNARCEKISCGPPSHVENAIARGVYYQYGDMITYSCYSGYMLEGSLRSVCLENGTW 3458
Query: 663 TELPECKEVKCPFPSRPENGFV 728
T P C+ V C FP +NG V
Sbjct: 3459 TPSPVCRAV-CRFPC--QNGGV 3477
Score = 63.5 bits (153), Expect = 2e-10
Identities = 55/221 (24%), Positives = 83/221 (36%), Gaps = 10/221 (4%)
Frame = +3
Query: 210 GEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPR-VCPFA--------GILENGA 362
G+ Y C GY S + IC G W + +PR + F ILE+
Sbjct: 2039 GDTAFYYCADGY-SLADNSQLICNAQGNWVPPAGQAVPRCIAHFCEKPPSVSYSILES-- 2095
Query: 363 VRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLS 542
V F + +SF C GF L + +C G+WSP A +
Sbjct: 2096 VSKAKFAAGSVVSFKCMEGFVLNTSAKIECLRGGEWSPSPLSVQCIPVRCGEPPSIA--N 2153
Query: 543 VYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTE-LPECKEVKCPFPSRPEN 719
Y +G N +G + C + G TC G W++ P C V C P + EN
Sbjct: 2154 GYP--SGTNYSFGAVVAYSCHKGFYIKGEKKSTCEATGQWSKPTPTCHPVSCNEPPKVEN 2211
Query: 720 GFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNW 842
GF+ + + ++ +A + C+ Y G C +W
Sbjct: 2212 GFLEHTTGRT--FESEARFQCNPGYKAAGSPVFVCQANRHW 2250
Score = 60.5 bits (145), Expect = 1e-09
Identities = 37/106 (34%), Positives = 48/106 (44%), Gaps = 2/106 (1%)
Frame = +3
Query: 549 KPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTE-LPECKEVKCPFPSRPENGF 725
+P +GN G K C P M GN C G WT+ LP C+ ++C P ENGF
Sbjct: 1641 RPASGNRKP-GSKVSLFCDPGFQMVGNPVQYCLNQGQWTQPLPHCERIRCGLPPALENGF 1699
Query: 726 VNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSA-QPSC 860
Y A+ + TY C Y L G + C G+W+ PSC
Sbjct: 1700 --YSAED-FHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSC 1742
Score = 58.9 bits (141), Expect = 4e-09
Identities = 43/182 (23%), Positives = 73/182 (39%), Gaps = 12/182 (6%)
Frame = +3
Query: 351 ENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKF 530
E+ A + F Y +S++C G+ L G C E+G W+
Sbjct: 2663 ESPASHASHFLYGTMVSYSCEPGYELLGIPVLICQEDGTWN-------------GTAPSC 2709
Query: 531 AKLSVYKPLAGNN-------SLYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPECKE 686
+ P+A N + G A + C P H + G+ C ++ W+ +P C+
Sbjct: 2710 ISIECDLPVAPENGFLHFTQTTMGSAAQYSCKPGHILEGSHLRLCLQNKQWSGTVPRCEA 2769
Query: 687 VKCPFPSRPENGFV---NYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSA-QP 854
+ C P+ NG + +Y VLYY+ C Y L+G ++ C + +W +P
Sbjct: 2770 ISCSKPNPLWNGSIKGDDYSYLGVLYYE------CDSGYILNGSKKRTCQENRDWDGHEP 2823
Query: 855 SC 860
C
Sbjct: 2824 MC 2825
Score = 54.3 bits (129), Expect = 9e-08
Identities = 51/223 (22%), Positives = 79/223 (34%), Gaps = 2/223 (0%)
Frame = +3
Query: 210 GEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYTTFEYP 389
G+ + C G+ G + C G W L C C + N V +
Sbjct: 3022 GKTVQIECFKGFKLLG-LSEITCDANGQWSDVPL-CEHAQCGPLPTIPNAIVLEGSLSED 3079
Query: 390 NTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNN 569
N ++++C G++++G++ CTE+ WS A + G
Sbjct: 3080 NVVTYSCRPGYTMQGSSDLICTEKAIWSQPYPTCEPLSCGPPPTVANAVAT------GEA 3133
Query: 570 SLYGGKAVFECLPQHAMFGN-GTITCTEHGNWT-ELPECKEVKCPFPSRPENGFVNYPAK 743
Y K CL + M + T TC + G+W E C KCP PS +
Sbjct: 3134 HTYESKVKLRCLEGYVMDSDTDTFTCQQDGHWVPERITCSPKKCPVPSNMTRIRFHGDDF 3193
Query: 744 QVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQPSCKASC 872
QV + + C + +T +G C G W P SC
Sbjct: 3194 QV---NRQVSVSCAEGFTHEGVNWSTCQPDGTWE-PPFSDESC 3232
Score = 49.7 bits (117), Expect = 2e-06
Identities = 53/267 (19%), Positives = 94/267 (34%), Gaps = 55/267 (20%)
Frame = +3
Query: 237 PGYVSRGGIRR---FICPLTGLWPINTLKCLPRVCP-FAGILENGAVRYTTFEYPNTISF 404
P +SRG + F+ +TG +++ CP G + + + + +S
Sbjct: 1596 PEELSRGNVLAWPDFLSGITGKVKVDSSSMFCSDCPSLEGSVPHLRPASGNRKPGSKVSL 1655
Query: 405 TCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLY-- 578
C+ GF + G C +G+W+ L ++ P A N Y
Sbjct: 1656 FCDPGFQMVGNPVQYCLNQGQWTQPL-------------PHCERIRCGLPPALENGFYSA 1702
Query: 579 -----GGKAVFECLPQHAMFGNGTITCTEHGNWTEL-PEC-------------------- 680
G ++C + + G+ + CT++G+W + P C
Sbjct: 1703 EDFHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASCLN 1762
Query: 681 ---------------------KEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYT 797
+ VKC P PENG + + ++ T+ C + +
Sbjct: 1763 TNGSYVCSCNPPYTGDGKNCAEPVKCKAPENPENG---HSSGEIYTVGTAVTFSCDEGHE 1819
Query: 798 LDGPEEVECNKFGNWS-AQPSCKA-SC 872
L G + C + G W +PSC+A SC
Sbjct: 1820 LVGVSTITCLETGEWDRLRPSCEAISC 1846
Score = 49.3 bits (116), Expect = 3e-06
Identities = 60/252 (23%), Positives = 85/252 (32%), Gaps = 9/252 (3%)
Frame = +3
Query: 147 CP----KPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLK 314
CP KPE P + S+ P ++ +T PG S C + +
Sbjct: 324 CPSGTYKPEASPGGI-----STCIPCPDVSHTSPPGSTSPED-----CVCREGYQRSGQT 373
Query: 315 CLPRVCPFAGILENGAVRYTTFE--YPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXX 488
C CP ENG T + + C GF L G++ C G WS
Sbjct: 374 CEVVHCPALKPPENGFFIQNTCKNHFNAACGVRCRPGFDLVGSSIHLCQPNGLWSGTESF 433
Query: 489 XXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT- 665
K +S N+L + C + + G+ +TC + W
Sbjct: 434 CRVRTCPHLRQPKHGHISCSTAEMSYNTL----CLVTCNEGYRLEGSTRLTCQGNAQWDG 489
Query: 666 ELPECKEVKCPFPSRPENGFVNYPA--KQVLYYQDKATYGCHDTYTLDGPEEVECNKFGN 839
P C E C +P+ ++ P+ KQ C Y L G EV C G
Sbjct: 490 PEPRCVERHCATFQKPKGVIISPPSCGKQPARPGMTCQLSCRQGYILSGVREVRCATSGK 549
Query: 840 WSAQPSCKASCK 875
WSA+ A CK
Sbjct: 550 WSAKVQ-TAVCK 560
>gi|6755452|ref|NP_035475.1| (NM_011345) selectin, endothelial cell
[Mus musculus]
Length = 619
Score = 89.0 bits (219), Expect = 3e-18
Identities = 55/231 (23%), Positives = 95/231 (40%), Gaps = 9/231 (3%)
Frame = +3
Query: 198 SYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYT- 374
SY + C GY R G + C +G+W T C C +NG V +
Sbjct: 269 SYPWNTTCTFDCVEGY-RRVGAQNLQCTSSGIWDNETPSCKAVTCDAIPQPQNGFVSCSH 327
Query: 375 ----TFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLS 542
+ ++ +FTC + F+L+G +C+ +G+W+P + + +
Sbjct: 328 STAGELAFKSSCNFTCEQSFTLQGPAQVECSAQGQWTPQIPVCKAVQCEALSAPQQGNMK 387
Query: 543 VYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNW-TELPECKEVKCPFPSRPEN 719
P A G F C + G+ + C G W ++ P C VKC RP+N
Sbjct: 388 CL-PSASGPFQNGSSCEFSCEEGFELKGSRRLQCGPRGEWDSKKPTCSAVKCDDVPRPQN 446
Query: 720 GFVN--YPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQ-PSCK 863
G + + Y+ + C++ ++L G ++EC G W+ + PSC+
Sbjct: 447 GVMECAHATTGEFTYKSSCAFQCNEGFSLHGSAQLECTSQGKWTQEVPSCQ 497
Score = 80.5 bits (197), Expect = 1e-15
Identities = 54/191 (28%), Positives = 81/191 (42%), Gaps = 7/191 (3%)
Frame = +3
Query: 315 CLPRVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKG-ANSAKCTEEGKWSPDLXXX 491
C P+ P G L N + + F Y ++ SF C RG+ + +CT G+WS
Sbjct: 187 CKPQEHPDYGSL-NCSHPFGPFSYNSSCSFGCKRGYLPSSMETTVRCTSSGEWSAPAPAC 245
Query: 492 XXXXXXXXXXXKFAKLSVYKPLAGNNSLY--GGKAVFECLPQHAMFGNGTITCTEHGNW- 662
+ + N Y F+C+ + G + CT G W
Sbjct: 246 HVVECEALTHPAHG----IRKCSSNPGSYPWNTTCTFDCVEGYRRVGAQNLQCTSSGIWD 301
Query: 663 TELPECKEVKCPFPSRPENGFV--NYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFG 836
E P CK V C +P+NGFV ++ L ++ + C ++TL GP +VEC+ G
Sbjct: 302 NETPSCKAVTCDAIPQPQNGFVSCSHSTAGELAFKSSCNFTCEQSFTLQGPAQVECSAQG 361
Query: 837 NWSAQ-PSCKA 866
W+ Q P CKA
Sbjct: 362 QWTPQIPVCKA 372
Score = 76.6 bits (187), Expect = 2e-14
Identities = 51/221 (23%), Positives = 85/221 (38%), Gaps = 7/221 (3%)
Frame = +3
Query: 225 YTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYTT-----FEYP 389
+TC+ + +G + C G W C C + G ++ F+
Sbjct: 341 FTCEQSFTLQGPAQ-VECSAQGQWTPQIPVCKAVQCEALSAPQQGNMKCLPSASGPFQNG 399
Query: 390 NTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNN 569
++ F+C GF LKG+ +C G+W + + G
Sbjct: 400 SSCEFSCEEGFELKGSRRLQCGPRGEWDSKKPTCSAVKCDDVPRPQNGVMECAHATTGEF 459
Query: 570 SLYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPECKEVKCPFPSRPENGFVNYPAKQ 746
+ Y F+C ++ G+ + CT G WT E+P C+ V+CP P G +N
Sbjct: 460 T-YKSSCAFQCNEGFSLHGSAQLECTSQGKWTQEVPSCQVVQCPSLDVP--GKMNMSCSG 516
Query: 747 VLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQ-PSCKA 866
+ + C D +TL+G + C G WS P+C+A
Sbjct: 517 TAVFGTVCEFTCPDDWTLNGSAVLTCGATGRWSGMPPTCEA 557
Score = 66.2 bits (160), Expect = 2e-11
Identities = 43/173 (24%), Positives = 69/173 (39%), Gaps = 5/173 (2%)
Frame = +3
Query: 210 GEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVC-----PFAGILENGAVRYT 374
G ++C+ G+ +G RR C G W C C P G++E
Sbjct: 399 GSSCEFSCEEGFELKGS-RRLQCGPRGEWDSKKPTCSAVKCDDVPRPQNGVMECAHATTG 457
Query: 375 TFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKP 554
F Y ++ +F CN GFSL G+ +CT +GKW+ ++ +S
Sbjct: 458 EFTYKSSCAFQCNEGFSLHGSAQLECTSQGKWTQEVPSCQVVQCPSLDVPGKMNMS---- 513
Query: 555 LAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTELPECKEVKCPFPSRP 713
+++G F C + G+ +TC G W+ +P E P+RP
Sbjct: 514 -CSGTAVFGTVCEFTCPDDWTLNGSAVLTCGATGRWSGMPPTCEAPVS-PTRP 564
>gi|6755456|ref|NP_035477.1| (NM_011347) selectin, platelet; P
selectin [Mus musculus]
Length = 768
Score = 86.3 bits (212), Expect = 2e-17
Identities = 69/257 (26%), Positives = 111/257 (42%), Gaps = 11/257 (4%)
Frame = +3
Query: 129 AIAGRTCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLW--PI 302
A+ ++ P A + P+ +++A + CQPGY +RG C +G W P+
Sbjct: 259 AVQCQSLEAPPHGTMACMHPI-AAFAYDSSCKFECQPGYRARGS-NTLHCTGSGQWSEPL 316
Query: 303 NT---LKCLPRVCPFAGILENGAVRYT-TFEYPNTISFTCNRGFSLKGANSAKCTEEGKW 470
T + C P P G ++ V T TF Y ++ +F C GF LKG ++ +C + G+W
Sbjct: 317 PTCEAIACEPPEIPIHGSMD--CVPSTGTFGYNSSCTFLCAEGFVLKGNDAIQCADSGQW 374
Query: 471 SPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTE 650
+ A+++ P Y F C + G I C
Sbjct: 375 TAPAPFCEALQCPEFPVPSKAQVNCSDPF--GTLTYQSVCSFSCDEGSLLVGASVIRCLA 432
Query: 651 HGNWTEL-PECKEVKCPFPSRPENGFVNYPAKQVL---YYQDKATYGCHDTYTLDGPEEV 818
G+W PEC+ V C PENG + Q L Y+ + C + + L GPE +
Sbjct: 433 TGHWNGAPPECQAVSCAPMLSPENG--SMTCVQPLGNSTYKSTCQFMCDEGFYLSGPERL 490
Query: 819 ECNKFGNWS-AQPSCKA 866
+C+ G+W+ P+C+A
Sbjct: 491 DCSPSGHWTGTPPTCEA 507
Score = 80.9 bits (198), Expect = 9e-16
Identities = 65/254 (25%), Positives = 96/254 (37%), Gaps = 12/254 (4%)
Frame = +3
Query: 153 KPEELPF---AVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLP 323
+P E+P VP ++ + C G+V +G C +G W C
Sbjct: 325 EPPEIPIHGSMDCVPSTGTFGYNSSCTFLCAEGFVLKGN-DAIQCADSGQWTAPAPFCEA 383
Query: 324 RVCPFAGILENGAVR----YTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXX 491
CP + V + T Y + SF+C+ G L GA+ +C G W+
Sbjct: 384 LQCPEFPVPSKAQVNCSDPFGTLTYQSVCSFSCDEGSLLVGASVIRCLATGHWNGAPPEC 443
Query: 492 XXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTEL 671
+ ++ +PL NS Y F C + G + C+ G+WT
Sbjct: 444 QAVSCAPMLSPENGSMTCVQPLG--NSTYKSTCQFMCDEGFYLSGPERLDCSPSGHWTGT 501
Query: 672 PE-CKEVKCPFPSRPENGFVNYPAKQV---LYYQDKATYGCHDTYTLDGPEEVECNKFGN 839
P C+ +KCP PE G N V + C++ + L G E VEC G
Sbjct: 502 PPTCEAIKCPGIFAPEQG--NLDCSHVHGEFGVGSICHFSCNEDFELLGSENVECTVSGR 559
Query: 840 WSA-QPSCKASCKL 878
WSA P+CK L
Sbjct: 560 WSAPPPTCKGITSL 573
Score = 77.0 bits (188), Expect = 1e-14
Identities = 43/166 (25%), Positives = 72/166 (42%), Gaps = 3/166 (1%)
Frame = +3
Query: 378 FEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPL 557
F + + +F+C G+ L G +C G W+ + ++ P+
Sbjct: 220 FSFNSQCTFSCAEGYELDGPGELQCLASGIWTNNPPKCDAVQCQSLEAPPHGTMACMHPI 279
Query: 558 AGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTE-LPECKEVKCPFPSRPENGFVN- 731
A Y FEC P + G+ T+ CT G W+E LP C+ + C P P +G ++
Sbjct: 280 AA--FAYDSSCKFECQPGYRARGSNTLHCTGSGQWSEPLPTCEAIACEPPEIPIHGSMDC 337
Query: 732 YPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSA-QPSCKA 866
P+ Y T+ C + + L G + ++C G W+A P C+A
Sbjct: 338 VPSTGTFGYNSSCTFLCAEGFVLKGNDAIQCADSGQWTAPAPFCEA 383
Score = 58.9 bits (141), Expect = 4e-09
Identities = 54/225 (24%), Positives = 81/225 (36%), Gaps = 28/225 (12%)
Frame = +3
Query: 276 CPLTGLW-----PINTLKCLPRVCPFAGILENGAVRYT----TFEYPNTISFTCNRGFSL 428
C TG W + C P + P ENG++ Y +T F C+ GF L
Sbjct: 430 CLATGHWNGAPPECQAVSCAPMLSP-----ENGSMTCVQPLGNSTYKSTCQFMCDEGFYL 484
Query: 429 KGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGN---NSLYGGKAV-- 593
G C+ G W+ ++ P GN + ++G V
Sbjct: 485 SGPERLDCSPSGHWT----------GTPPTCEAIKCPGIFAPEQGNLDCSHVHGEFGVGS 534
Query: 594 ---FECLPQHAMFGNGTITCTEHGNWTELPE-CK--------EVKCPFPSRPENGFVNYP 737
F C + G+ + CT G W+ P CK V+CP + P G ++
Sbjct: 535 ICHFSCNEDFELLGSENVECTVSGRWSAPPPTCKGITSLPAPAVRCPALTTPGQGTMSCQ 594
Query: 738 AKQVLYYQDKATY-GCHDTYTLDGPEEVECNKFGNWSA-QPSCKA 866
+ + Y GC +TL G + C G W+A P C+A
Sbjct: 595 HHLGSFGPNTTCYFGCKTGFTLRGANSLRCRASGQWTAVTPMCRA 639
Score = 51.2 bits (121), Expect = 8e-07
Identities = 29/101 (28%), Positives = 45/101 (43%), Gaps = 2/101 (1%)
Frame = +3
Query: 387 PNTIS-FTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAG 563
PNT F C GF+L+GANS +C G+W+ ++ P
Sbjct: 602 PNTTCYFGCKTGFTLRGANSLRCRASGQWTAVTPMCRAVKCSELHMDTAVAMNCSNPWG- 660
Query: 564 NNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTE-LPECK 683
N YG F+C ++ G+ TC E G+W++ +P C+
Sbjct: 661 -NFSYGSTCTFQCPEGQSLNGSVRATCREDGHWSDAMPTCQ 700
Score = 47.4 bits (111), Expect = 1e-05
Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 4/96 (4%)
Frame = +3
Query: 198 SYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPF----AGILENGAV 365
S+ P + C+ G+ RG C +G W T C C + N +
Sbjct: 599 SFGPNTTCYFGCKTGFTLRGA-NSLRCRASGQWTAVTPMCRAVKCSELHMDTAVAMNCSN 657
Query: 366 RYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWS 473
+ F Y +T +F C G SL G+ A C E+G WS
Sbjct: 658 PWGNFSYGSTCTFQCPEGQSLNGSVRATCREDGHWS 693
Score = 39.7 bits (91), Expect = 0.002
Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Frame = +3
Query: 630 GTITCTEHGNWTELPECKEVK-CPFPSRPENGFVN--YPAKQVLYYQDKATYGCHDTYTL 800
G+ TC+ + + PEC+ VK C + P++ +N +P + + + T+ C + Y L
Sbjct: 179 GSYTCSCYPGFYG-PECEYVKECGKVNIPQHVLMNCSHPLGE-FSFNSQCTFSCAEGYEL 236
Query: 801 DGPEEVECNKFGNWSAQP 854
DGP E++C G W+ P
Sbjct: 237 DGPGELQCLASGIWTNNP 254
>gi|16716457|ref|NP_444401.1| (NM_053171) CUB and Sushi multiple
domains 1 [Mus musculus]
Length = 3564
Score = 82.0 bits (201), Expect = 4e-16
Identities = 56/221 (25%), Positives = 87/221 (39%), Gaps = 2/221 (0%)
Frame = +3
Query: 213 EEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYTTFEYPN 392
+ +VY C PG+ G R C T T+ C+P C G +G T F +
Sbjct: 2700 DTVVYQCNPGFRLVGTSVRICCRTTSGRGRLTV-CVPITCGHPGNPAHGLTNGTEFNLND 2758
Query: 393 TISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNS 572
++FTC+ G+ L+GA+ A+C G+WS L + A + +
Sbjct: 2759 LVNFTCHTGYRLQGASRAQCRSNGQWSSPLPICRVVNCSDPGSVENAVRHGQQNFP-ESF 2817
Query: 573 LYGGKAVFECLPQHAMFGNGTITCTEHGNW-TELPECKEVKCPFPSRPENGFVNYPAKQV 749
YG ++ C + G+ +TC G W LP+C + C P P N + ++
Sbjct: 2818 EYGTSVMYHCKTGFYLLGSSALTCMASGLWDRSLPKCLAISCGHPGVPANAVL---TGEL 2874
Query: 750 LYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQ-PSCKAS 869
Y Y C L G C + +WS P C +
Sbjct: 2875 FTYGATVQYSCKGGQILTGNSTRVCQEDSHWSGSLPHCSGN 2915
Score = 75.9 bits (185), Expect = 3e-14
Identities = 56/222 (25%), Positives = 81/222 (36%), Gaps = 4/222 (1%)
Frame = +3
Query: 210 GEEIVYTCQPGYVSRGGIRRFICPLTGLWPI--NTLKCLPRVCPFAGILENGAVRYTTFE 383
G +++ +C PGY +G R C G W + +C C NG T
Sbjct: 2581 GAQVLLSCSPGYFLQGQ-RLLQCQANGTWSTEEDRPRCKVISCGSLSFPPNGNKIGTLTI 2639
Query: 384 YPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAG 563
Y T FTCN G++L G++ +C G WS V ++G
Sbjct: 2640 YGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPI------VNGHISG 2693
Query: 564 NNSLYGGKAVFECLPQHAMFGNGT-ITCTEHGNWTELPECKEVKCPFPSRPENGFVNYPA 740
+ Y V++C P + G I C L C + C P P +G N
Sbjct: 2694 DGFSYRDTVVYQCNPGFRLVGTSVRICCRTTSGRGRLTVCVPITCGHPGNPAHGLTNGTE 2753
Query: 741 KQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQ-PSCK 863
+ D + CH Y L G +C G WS+ P C+
Sbjct: 2754 FNL---NDLVNFTCHTGYRLQGASRAQCRSNGQWSSPLPICR 2792
Score = 74.3 bits (181), Expect = 9e-14
Identities = 52/218 (23%), Positives = 87/218 (39%), Gaps = 4/218 (1%)
Frame = +3
Query: 219 IVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRYTTFEYPNTI 398
++Y C GY + G + R C G W C C G L NG T F + T+
Sbjct: 3001 VIYACWEGYKTSGLMTRH-CTANGTWTGTAPDCTIISCGDPGTLPNGIQFGTDFTFNKTV 3059
Query: 399 SFTCNRGFSLKGANS--AKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNS 572
S+ CN G+ ++ S +CT++G W+ K+ G++
Sbjct: 3060 SYQCNPGYLMEPPTSPTIRCTKDGTWNQSRPLCKAVLCNQPPPVPNGKVE------GSDF 3113
Query: 573 LYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPECKEVKCPFPSRPENGFVNYPAKQV 749
+G + C+ + + + ++C G W E+P+C V C P P G + + +
Sbjct: 3114 RWGASISYSCVDGYQLSHSAILSCEGRGVWKGEVPQCLPVFCGDPGTPAEGRL---SGKS 3170
Query: 750 LYYQDKATYGCHDTYTLDGPEEVECNKFGNWSA-QPSC 860
++ + C + L G C G WS QP+C
Sbjct: 3171 FTFKSEVFIQCKPPFVLVGSSRRTCQADGIWSGIQPTC 3208
Score = 70.5 bits (171), Expect = 1e-12
Identities = 56/228 (24%), Positives = 91/228 (39%), Gaps = 10/228 (4%)
Frame = +3
Query: 192 KSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGL----WPINTLKCLPRVCPFAGILENG 359
K++ A G ++ Y C+PGY G C + W C C NG
Sbjct: 2446 KTAGAVGSKVHYFCKPGYRMIGHSNA-TCRRNPVGVYQWDSMAPLCQAVSCGIPEAPGNG 2504
Query: 360 AVRYTTFEYPNTISFTCNRGFSLKGANSAK--CTEEGKWSP-DLXXXXXXXXXXXXXXKF 530
+ F + +++ CN GF L + A C E+G WS +
Sbjct: 2505 SFTGNEFTLDSKVTYECNEGFKLDASQEATTVCQEDGLWSNRGKPPTCKPVPCPSIEGQL 2564
Query: 531 AKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT---ELPECKEVKCPF 701
++ +++ ++G+ + YG + + C P + + G + C +G W+ + P CK + C
Sbjct: 2565 SEHVLWRLVSGSLNEYGAQVLLSCSPGYFLQGQRLLQCQANGTWSTEEDRPRCKVISCGS 2624
Query: 702 PSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWS 845
S P NG + Y A + C+ YTL G EC G WS
Sbjct: 2625 LSFPPNG---NKIGTLTIYGATAIFTCNTGYTLVGSHVRECLANGLWS 2669
Score = 63.9 bits (154), Expect = 1e-10
Identities = 51/226 (22%), Positives = 85/226 (37%), Gaps = 7/226 (3%)
Frame = +3
Query: 210 GEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCL---PRVCPFAGILENGAVRYTTF 380
G + Y+C+ G + G R +C W + C P C G +G+ F
Sbjct: 2878 GATVQYSCKGGQILTGNSTR-VCQEDSHWSGSLPHCSGNSPGFCGDPGTPAHGSRLGDEF 2936
Query: 381 EYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVYKPLA 560
+ + + F+C G L+G C G WS + L+
Sbjct: 2937 KTKSLLRFSCEMGHQLRGFAERTCLVNGSWSGVQPVCEAVSCGNPGTPTNGMI-----LS 2991
Query: 561 GNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPECKEVKCPFPSRPENGFVNYP 737
+ L+ ++ C + G T CT +G WT P+C + C P NG + +
Sbjct: 2992 SDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLPNG-IQFG 3050
Query: 738 AKQVLYYQDKATYGCHDTYTLDGPEE--VECNKFGNWS-AQPSCKA 866
+ +Y C+ Y ++ P + C K G W+ ++P CKA
Sbjct: 3051 TD--FTFNKTVSYQCNPGYLMEPPTSPTIRCTKDGTWNQSRPLCKA 3094
Score = 58.5 bits (140), Expect = 5e-09
Identities = 61/254 (24%), Positives = 91/254 (35%), Gaps = 4/254 (1%)
Frame = +3
Query: 117 LCHAAIAGRTCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGY-VSRGGIRRFICPLTGL 293
LC A + C +P +P V S + G I Y+C GY +S I C G+
Sbjct: 3091 LCKAVL----CNQPPPVPNGKVEG--SDFRWGASISYSCVDGYQLSHSAI--LSCEGRGV 3142
Query: 294 WPINTLKCLPRVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWS 473
W +CLP C G G + +F + + + C F L G++ C +G WS
Sbjct: 3143 WKGEVPQCLPVFCGDPGTPAEGRLSGKSFTFKSEVFIQCKPPFVLVGSSRRTCQADGIWS 3202
Query: 474 PDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEH 653
+ G G F C + + G+ T TC +
Sbjct: 3203 GIQPTCIDPAHTACPDPGTPHFGIQNSSKGYE--VGSTVFFRCRKGYHIQGSTTRTCLAN 3260
Query: 654 GNWTEL-PECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTL-DGPEEVECN 827
W+ + EC C P P + V A + + Y CH + L G E C
Sbjct: 3261 LTWSGIQTECIPHACRQPETPAHADVR--AIDLPAFGYTLVYTCHPGFFLAGGSEHRTCK 3318
Query: 828 KFGNWSAQ-PSCKA 866
W+ + P CK+
Sbjct: 3319 ADMKWTGKSPVCKS 3332
Score = 40.0 bits (92), Expect = 0.002
Identities = 48/202 (23%), Positives = 66/202 (31%), Gaps = 21/202 (10%)
Frame = +3
Query: 330 CPFAGILENGAV-RYTTFEYPNTISFTCNRGFSLKGANSAKCTEE--GKWSPDLXXXXXX 500
C L NG + T + + + C G+ + G ++A C G + D
Sbjct: 2432 CSLTSTLRNGGILNKTAGAVGSKVHYFCKPGYRMIGHSNATCRRNPVGVYQWDSMAPLCQ 2491
Query: 501 XXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGN--GTITCTEHGNWTEL- 671
S GN K +EC + + T C E G W+
Sbjct: 2492 AVSCGIPEAPGNGS----FTGNEFTLDSKVTYECNEGFKLDASQEATTVCQEDGLWSNRG 2547
Query: 672 --PECKEVKCPFPS---------RPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEV 818
P CK V CP R +G +N QVL C Y L G +
Sbjct: 2548 KPPTCKPVPCPSIEGQLSEHVLWRLVSGSLNEYGAQVLL-------SCSPGYFLQGQRLL 2600
Query: 819 ECNKFGNWSAQ---PSCKA-SC 872
+C G WS + P CK SC
Sbjct: 2601 QCQANGTWSTEEDRPRCKVISC 2622
Score = 33.5 bits (75), Expect = 0.17
Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Frame = +3
Query: 537 LSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPECKEVKCPFPSRP 713
+ Y G++ L+G FEC + G ITC ++ W+ P C C F
Sbjct: 532 IPAYGKRTGSSFLHGDTLTFECQAAFELVGERVITCQKNNQWSGNKPSC-VFSCFFNFTA 590
Query: 714 ENGFV---NYP 737
+G + NYP
Sbjct: 591 PSGIILSPNYP 601
Score = 32.3 bits (72), Expect = 0.38
Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Frame = +3
Query: 771 TYGCHDTYTLDGPEEVECNKFGNWS-AQPSCKASC--KLSVKRATVIYEG 911
T+ C YTL E + C K W+ A PSC A C + K TV+ G
Sbjct: 896 TFSCDPGYTLSDDEPLVCEKNHQWNHALPSCDALCGGYIHGKSGTVLSPG 945
Score = 31.6 bits (70), Expect = 0.64
Identities = 18/57 (31%), Positives = 27/57 (46%), Gaps = 4/57 (7%)
Frame = +3
Query: 579 GGKAVFECLPQHAMFGNGTITCTEHG---NWT-ELPECKEVKCPFPSRPENGFVNYP 737
G FEC P + + G+ +TC +HG NW P C + C + +NG + P
Sbjct: 2106 GQSISFECYPGYILLGHPVLTC-QHGTDRNWNYPFPRC-DAPCGYNVTSQNGTIYSP 2160
Score = 31.2 bits (69), Expect = 0.84
Identities = 14/38 (36%), Positives = 18/38 (46%), Gaps = 1/38 (2%)
Frame = +3
Query: 762 DKATYGCHDTYTLDGPEEVECNKFGNWSA-QPSCKASC 872
D T+ C + L G + C K WS +PSC SC
Sbjct: 547 DTLTFECQAAFELVGERVITCQKNNQWSGNKPSCVFSC 584
Score = 30.4 bits (67), Expect = 1.4
Identities = 16/53 (30%), Positives = 25/53 (46%), Gaps = 3/53 (5%)
Frame = +3
Query: 330 CPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGK---WSPD 479
C G+ +NG + E +TI+F C+ G+ L+G C + W PD
Sbjct: 1391 CNDPGMPQNGTRYGDSREPGDTITFQCDPGYQLQGPAKITCVQLNNRFFWQPD 1443
Score = 30.4 bits (67), Expect = 1.4
Identities = 13/42 (30%), Positives = 20/42 (46%)
Frame = +3
Query: 327 VCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKC 452
+CP GI +NG + F + F+C + L+GA C
Sbjct: 348 MCPDPGIPDNGRRAGSDFRVGANVQFSCEDNYVLQGAKGITC 389
Score = 30.0 bits (66), Expect = 1.9
Identities = 12/39 (30%), Positives = 19/39 (47%)
Frame = +3
Query: 141 RTCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRG 257
+ CP P +P A ++ + G+ + Y C PGY G
Sbjct: 2256 KRCPPPPAVPQADLLTEDEDFEIGDFVKYQCHPGYTLLG 2294
Score = 30.0 bits (66), Expect = 1.9
Identities = 13/48 (27%), Positives = 24/48 (49%)
Frame = +3
Query: 330 CPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWS 473
C GI NG + F +T++F+C+ G++L C + +W+
Sbjct: 873 CLDPGIPVNGQRHGSNFGIRSTVTFSCDPGYTLSDDEPLVCEKNHQWN 920
Score = 30.0 bits (66), Expect = 1.9
Identities = 14/48 (29%), Positives = 22/48 (45%)
Frame = +3
Query: 330 CPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWS 473
C GI G ++F + +T++F C F L G C + +WS
Sbjct: 527 CGDPGIPAYGKRTGSSFLHGDTLTFECQAAFELVGERVITCQKNNQWS 574
Score = 29.3 bits (64), Expect = 3.2
Identities = 14/47 (29%), Positives = 22/47 (46%)
Frame = +3
Query: 117 LCHAAIAGRTCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRG 257
L + A + CP P ++ S Y+ G+ I + C PGY+ G
Sbjct: 2077 LSYQAYELQNCPDPPAFQNGFMI--NSDYSVGQSISFECYPGYILLG 2121
Score = 28.1 bits (61), Expect = 7.1
Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 6/66 (9%)
Frame = +3
Query: 693 CPFPSRPENGFV---NYPAKQVLYYQDKATYGCHDTYTLDGPEEVEC--NKFGNWS-AQP 854
C P+ P NG Y VL +Q C YTL G + C W+ P
Sbjct: 1915 CQEPALPSNGIKIGDRYMVNDVLSFQ------CEPGYTLQGRSHISCMPGTVRRWNYPSP 1968
Query: 855 SCKASC 872
C A+C
Sbjct: 1969 LCIATC 1974
Score = 27.7 bits (60), Expect = 9.3
Identities = 14/40 (35%), Positives = 18/40 (45%), Gaps = 3/40 (7%)
Frame = +3
Query: 762 DKATYGCHDTYTLDGPEEVECNKFGNWSAQ---PSCKASC 872
D Y CH YTL G + + C Q P+C+A C
Sbjct: 2280 DFVKYQCHPGYTLLGSDTLTCKLSSQLLFQGSPPTCEAQC 2319
>gi|31542275|ref|NP_031602.2| (NM_007576) complement component 4
binding protein [Mus musculus]
Length = 426
Score = 80.9 bits (198), Expect = 9e-16
Identities = 69/264 (26%), Positives = 110/264 (41%), Gaps = 14/264 (5%)
Frame = +3
Query: 129 AIAGRTCPKPEELPFAVVVP--LKSSYAPGEEIVYTCQPGYVSRGGIRRFI-CPLTGLWP 299
A+ G+ C P +P A+ ++ + + Y C PGY RG R + C +G W
Sbjct: 10 AVFGK-CGPPPAIPNALPASDVNRTDFESHTTLKYECLPGY-GRGISRMTVYCKPSGEWE 67
Query: 300 INTLKCLPRVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGK---W 470
I+ + C + C G L+NG V T + + I F+C GF L G++++ C GK W
Sbjct: 68 IS-VSCAKKHCRNPGYLDNGYVNGETITFGSQIEFSCQEGFILVGSSTSSCEVRGKGVAW 126
Query: 471 S---PDLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTIT 641
S P+ K + + P Y + C P + G+ I
Sbjct: 127 SNPFPECVIVKCGPPPDISNGKHSGTEDFYP-------YNHGISYTCDPGFRLVGSPFIG 179
Query: 642 CTEHGN----WTEL-PECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDG 806
CT W+ P C+++ C P+ +G + K ++D C + L G
Sbjct: 180 CTVVNKTVPVWSSSPPTCEKIICSQPN-ILHGVIVSGYKATYTHRDSVRLACLNGTVLRG 238
Query: 807 PEEVECNKFGNWSAQPSCKASCKL 878
+EC GNWS+ P+C+ C L
Sbjct: 239 RHVIECQGNGNWSSLPTCEFDCDL 262
Score = 65.9 bits (159), Expect = 3e-11
Identities = 72/257 (28%), Positives = 93/257 (36%), Gaps = 17/257 (6%)
Frame = +3
Query: 210 GEEIVYTCQPGYVSRGGIRRFICPLTG---LWPINTLKCLPRVCPFAGILENGAVRYTTF 380
G +I ++CQ G++ G C + G W +C+ C + NG T
Sbjct: 96 GSQIEFSCQEGFILVGSSTSS-CEVRGKGVAWSNPFPECVIVKCGPPPDISNGKHSGTED 154
Query: 381 EYP--NTISFTCNRGFSLKGANSAKCTEEGK----WSPDLXXXXXXXXXXXXXXKFAKLS 542
YP + IS+TC+ GF L G+ CT K WS +S
Sbjct: 155 FYPYNHGISYTCDPGFRLVGSPFIGCTVVNKTVPVWSSSPPTCEKIICSQPNILHGVIVS 214
Query: 543 VYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTELPECKEVKCPFPSRPENG 722
YK + CL + G I C +GNW+ LP C E C P NG
Sbjct: 215 GYKATYTHRD----SVRLACLNGTVLRGRHVIECQGNGNWSSLPTC-EFDCDLPPAIVNG 269
Query: 723 FVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQ-PSCKASC-KLSVKRAT 896
Y V TY C Y L G + C+ F W P CKA C K V T
Sbjct: 270 ---YYTSMVYSKITLVTYECDKGYRLVGKAIISCS-FSKWKGTAPQCKALCQKPEVGNGT 325
Query: 897 V------IYEGERVNIQ 929
+ E E V IQ
Sbjct: 326 LSDEKDQYVESENVTIQ 342
Score = 50.4 bits (119), Expect = 1e-06
Identities = 46/190 (24%), Positives = 72/190 (37%), Gaps = 10/190 (5%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFI-CPLTGLWPINTLKCLP 323
C +P L +V K++Y + + C G V RG R I C G W ++L
Sbjct: 202 CSQPNILHGVIVSGYKATYTHRDSVRLACLNGTVLRG--RHVIECQGNGNW--SSLPTCE 257
Query: 324 RVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXX 503
C + NG + +++ C++G+ L G C+ KW
Sbjct: 258 FDCDLPPAIVNGYYTSMVYSKITLVTYECDKGYRLVGKAIISCSFS-KWK---------- 306
Query: 504 XXXXXXXKFAKLSVYKPLAGNNSLYGGK--------AVFECLPQHAMFGNGTITCTEHGN 659
K KP GN +L K +C AM G+ +I+C+E G
Sbjct: 307 ----GTAPQCKALCQKPEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGT 362
Query: 660 W-TELPECKE 686
W E+P C++
Sbjct: 363 WYPEVPRCEQ 372
Score = 48.9 bits (115), Expect = 4e-06
Identities = 53/258 (20%), Positives = 92/258 (35%), Gaps = 9/258 (3%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFI-CPLTG----LWPINTL 311
C P ++ + Y I YTC PG+ G FI C + +W +
Sbjct: 138 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGS--PFIGCTVVNKTVPVWSSSPP 195
Query: 312 KCLPRVCPFAGILENGAVR--YTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLX 485
C +C IL V T+ + +++ C G L+G + +C G WS
Sbjct: 196 TCEKIICSQPNILHGVIVSGYKATYTHRDSVRLACLNGTVLRGRHVIECQGNGNWSSLPT 255
Query: 486 XXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT 665
+ VY + +EC + + G I+C+
Sbjct: 256 CEFDCDLPPAIVNGYYTSMVYSKIT--------LVTYECDKGYRLVGKAIISCSFSKWKG 307
Query: 666 ELPECKEVKCPFPSRPENGFVNYPAKQVLYYQ-DKATYGCHDTYTLDGPEEVECNKFGNW 842
P+CK + C +PE G ++ Y + + T C + + G + + C++ G W
Sbjct: 308 TAPQCKAL-C---QKPEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTW 363
Query: 843 SAQ-PSCKASCKLSVKRA 893
+ P C+ +K A
Sbjct: 364 YPEVPRCEQEASEDLKPA 381
Score = 36.6 bits (83), Expect = 0.020
Identities = 32/119 (26%), Positives = 52/119 (42%), Gaps = 6/119 (5%)
Frame = +3
Query: 144 TCPKPEELPFAVVVPLKSS--YAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKC 317
TC +LP A+V +S Y+ + Y C GY G + I W +C
Sbjct: 255 TCEFDCDLPPAIVNGYYTSMVYSKITLVTYECDKGYRLVG--KAIISCSFSKWKGTAPQC 312
Query: 318 LPRVC--PFAGILENGAVRYTTFEYPNT--ISFTCNRGFSLKGANSAKCTEEGKWSPDL 482
+C P G NG + +Y + ++ C+ GF++ G+ S C+E G W P++
Sbjct: 313 -KALCQKPEVG---NGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEV 367
>gi|13624321|ref|NP_112441.1| (NM_031164) coagulation factor XIII,
beta subunit [Mus musculus]
Length = 668
Score = 80.9 bits (198), Expect = 9e-16
Identities = 67/249 (26%), Positives = 107/249 (42%), Gaps = 10/249 (4%)
Frame = +3
Query: 144 TCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIR--RFICPLTGLWPINTLKC 317
TC PE L + ++ + + YTC GY + G + C G W + T +C
Sbjct: 152 TCLAPE-LEHGNYSTTQRTFKVKDIVAYTCTAGYYTTTGKQTGEAECQANG-WSL-TPQC 208
Query: 318 LPRVCPFAGILENGAVRYT--TFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXX 491
+C ++ENG T+E + + F C+ + L G++ +C G W P+
Sbjct: 209 NKLMCSSLRLIENGYFHPVKQTYEEGDLVQFFCHENYYLSGSDLIQCYNFG-WYPE---- 263
Query: 492 XXXXXXXXXXXKFAKLSVYKPLAGNNSLY--GGKAVFECLPQHAMFGNGTITCTEHGNWT 665
+ + + +++ Y G + EC + G+ + C E+G WT
Sbjct: 264 SPICEGRRNRCPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLC-ENGKWT 322
Query: 666 ELPECKEVK----CPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKF 833
E P+C E K C P ENG V +P ++ Y DK TY C Y+L G + CN+
Sbjct: 323 EPPKCIEEKEKVACEQPPSVENG-VAHPHSEIYYSGDKVTYRCGGGYSLRGSSTITCNR- 380
Query: 834 GNWSAQPSC 860
G W+ P C
Sbjct: 381 GRWTLPPEC 389
Score = 71.6 bits (174), Expect = 6e-13
Identities = 66/262 (25%), Positives = 100/262 (37%), Gaps = 10/262 (3%)
Frame = +3
Query: 186 PLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTL------KCLPRVCPFAGI 347
P+K +Y G+ + + C Y G C G +P + + +C P P
Sbjct: 226 PVKQTYEEGDLVQFFCHENYYLSGS-DLIQCYNFGWYPESPICEGRRNRCPPPPVPLNSK 284
Query: 348 LENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXK 527
++ + TT+ + + C F ++G+ C E GKW+
Sbjct: 285 IQPHS---TTYRHGERVHIECELNFVIQGSEELLC-ENGKWTEPPKCIEEKEKVACEQPP 340
Query: 528 FAKLSVYKPLAGNNSLY--GGKAVFECLPQHAMFGNGTITCTEHGNWTELPECKE--VKC 695
+ V P ++ +Y G K + C +++ G+ TITC G WT PEC E C
Sbjct: 341 SVENGVAHP---HSEIYYSGDKVTYRCGGGYSLRGSSTITCNR-GRWTLPPECVENIENC 396
Query: 696 PFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQPSCKASCK 875
P NG V Y C++ Y L G E C + G WS+ P C C
Sbjct: 397 KPPPDIANGVVVDGLLASYTTGSSVEYRCNEYYLLKGSETSRCEQ-GAWSSPPVCLEPCT 455
Query: 876 LSVKRATVIYEGERVNIQDKFK 941
+ V R NIQ K+K
Sbjct: 456 IDVDHM------NRNNIQLKWK 471
Score = 58.5 bits (140), Expect = 5e-09
Identities = 66/260 (25%), Positives = 99/260 (37%), Gaps = 15/260 (5%)
Frame = +3
Query: 147 CPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPI------NT 308
C +P + V P Y G+++ Y C GY RG I G W + N
Sbjct: 336 CEQPPSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRGSST--ITCNRGRWTLPPECVENI 393
Query: 309 LKCLPRVCPFAGILENGAVR-YTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWS-PDL 482
C P G++ +G + YTT +++ + CN + LKG+ +++C E+G WS P +
Sbjct: 394 ENCKPPPDIANGVVVDGLLASYTT---GSSVEYRCNEYYLLKGSETSRC-EQGAWSSPPV 449
Query: 483 XXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGN---GTITCTEH 653
+L K L+G F C + + + I+ +
Sbjct: 450 CLEPCTIDVDHMNRNNIQL---KWKYEGKILHGDLIDFVCKQGYNLSPSIPLSEISAQCN 506
Query: 654 GNWTELPEC--KEVK--CPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVE 821
P C KE K C P NG + A + Y C D + L G + V
Sbjct: 507 RGDVRYPMCIRKESKGMCASPPVIRNGDIVSSAARTYENGSSVEYRCFDNHFLQGSQNVY 566
Query: 822 CNKFGNWSAQPSCKASCKLS 881
C G W+ PSC C LS
Sbjct: 567 CVD-GVWTTPPSCLEPCTLS 585
Score = 52.0 bits (123), Expect = 5e-07
Identities = 63/281 (22%), Positives = 105/281 (36%), Gaps = 21/281 (7%)
Frame = +3
Query: 141 RTCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGG-IRRFICPLTGLWPINTLKC 317
+ C KP+ L V K Y E + Y C GY + GG + L+ W
Sbjct: 89 KKCLKPD-LRNGYVSNDKVLYKLQERMSYGCSSGYKTTGGKDEEVVHCLSAGWSSQPSCR 147
Query: 318 LPRVCPFAGILENGAVRYT--TFEYPNTISFTCNRGF---SLKGANSAKCTEEGKWSPDL 482
+ A LE+G T TF+ + +++TC G+ + K A+C G WS
Sbjct: 148 KEQETCLAPELEHGNYSTTQRTFKVKDIVAYTCTAGYYTTTGKQTGEAECQANG-WS--- 203
Query: 483 XXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNW 662
+ + + P+ G F C + + G+ I C G +
Sbjct: 204 -LTPQCNKLMCSSLRLIENGYFHPVKQTYE-EGDLVQFFCHENYYLSGSDLIQCYNFGWY 261
Query: 663 TELPEC--KEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFG 836
E P C + +CP P P N + P + ++ C + + G EE+ C G
Sbjct: 262 PESPICEGRRNRCPPPPVPLNSKIQ-PHSTTYRHGERVHIECELNFVIQGSEELLCEN-G 319
Query: 837 NWSAQPSC-----KASCK--------LSVKRATVIYEGERV 920
W+ P C K +C+ ++ + + Y G++V
Sbjct: 320 KWTEPPKCIEEKEKVACEQPPSVENGVAHPHSEIYYSGDKV 360
Score = 50.8 bits (120), Expect = 1e-06
Identities = 32/111 (28%), Positives = 50/111 (44%), Gaps = 11/111 (9%)
Frame = +3
Query: 630 GTITCTEHGNWTELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGP 809
G C +G W+ P+C ++ C ENG+ +P KQ D + CH+ Y L G
Sbjct: 193 GEAECQANG-WSLTPQCNKLMCSSLRLIENGYF-HPVKQTYEEGDLVQFFCHENYYLSGS 250
Query: 810 EEVECNKFGNWSAQPSCKA--------SCKLSVK---RATVIYEGERVNIQ 929
+ ++C FG + P C+ L+ K +T GERV+I+
Sbjct: 251 DLIQCYNFGWYPESPICEGRRNRCPPPPVPLNSKIQPHSTTYRHGERVHIE 301
Score = 43.1 bits (100), Expect = 2e-04
Identities = 32/80 (40%), Positives = 42/80 (52%), Gaps = 4/80 (5%)
Frame = +3
Query: 636 ITCTEHGNWTELPECKEVKCPFPSRPENGFVNYPAKQVLY-YQDKATYGCHDTYTLDG-- 806
I CT G W+ P C + KC P NG+V+ +VLY Q++ +YGC Y G
Sbjct: 74 IRCTAEG-WSPNPRCYK-KCLKPDL-RNGYVSND--KVLYKLQERMSYGCSSGYKTTGGK 128
Query: 807 -PEEVECNKFGNWSAQPSCK 863
E V C G WS+QPSC+
Sbjct: 129 DEEVVHCLSAG-WSSQPSCR 147
>gi|19072788|ref|NP_034018.1| (NM_009888) complement component factor
h; complement factor H related protein 3A4/5G4 [Mus
musculus]
Length = 1234
Score = 80.9 bits (198), Expect = 9e-16
Identities = 62/250 (24%), Positives = 98/250 (38%), Gaps = 5/250 (2%)
Frame = +3
Query: 138 GRTCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKC 317
G C P +P V SY GEE+ Y C G+ G FI G W + KC
Sbjct: 933 GLPCGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDG--PAFIICEGGKWS-DPPKC 989
Query: 318 LPRVCPFAGILENGAVR---YTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXX 488
+ C ++N +R ++ ++F C + + G+++ C +W
Sbjct: 990 IKTDCDVLPTVKNAIIRGKSKKSYRTGEQVTFRCQSPYQMNGSDTVTCV-NSRWIGQPVC 1048
Query: 489 XXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTE 668
++ K N L+G + +EC +FG + C E+G WTE
Sbjct: 1049 KDNSCVDPPHVPNATIVTRTK----NKYLHGDRVRYECNKPLELFGQVEVMC-ENGIWTE 1103
Query: 669 LPECKEV--KCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNW 842
P+C++ KC P +NG + + V Y C Y L G + + C G W
Sbjct: 1104 KPKCRDSTGKCGPPPPIDNGDITSLSLPVYEPLSSVEYQCQKYYLLKGKKTITCTN-GKW 1162
Query: 843 SAQPSCKASC 872
S P+C +C
Sbjct: 1163 SEPPTCLHAC 1172
Score = 72.0 bits (175), Expect = 4e-13
Identities = 56/257 (21%), Positives = 102/257 (38%), Gaps = 17/257 (6%)
Frame = +3
Query: 144 TCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLP 323
+CP P ++P V+ Y GE++ CQ Y+++ +C G W + +C+
Sbjct: 807 SCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDS-EEMVCK-DGRWQ-SLPRCIE 863
Query: 324 RV-CPFAGILENGAVRY-------------TTFEYPNTISFTCNRGFSLKGANSAKCTEE 461
++ C +E+G++ ++ E+ T S+ C+ GF + N C
Sbjct: 864 KIPCSQPPTIEHGSINLPRSSEERRDSIESSSHEHGTTFSYVCDDGFRIPEENRITCYM- 922
Query: 462 GKWSPD---LXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNG 632
GKWS + +L Y+ +G + + C + G
Sbjct: 923 GKWSTPPRCVGLPCGPPPSIPLGTVSLELESYQ--------HGEEVTYHCSTGFGIDGPA 974
Query: 633 TITCTEHGNWTELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPE 812
I C E G W++ P+C + C +N + +K+ ++ T+ C Y ++G +
Sbjct: 975 FIIC-EGGKWSDPPKCIKTDCDVLPTVKNAIIRGKSKKSYRTGEQVTFRCQSPYQMNGSD 1033
Query: 813 EVECNKFGNWSAQPSCK 863
V C W QP CK
Sbjct: 1034 TVTCVN-SRWIGQPVCK 1049
Score = 68.2 bits (165), Expect = 6e-12
Identities = 66/248 (26%), Positives = 99/248 (39%), Gaps = 8/248 (3%)
Frame = +3
Query: 141 RTCPKPEELPFAVV-VPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLW----PI- 302
+ C P + PF + + S + G ++VYTC GY G I C G W P+
Sbjct: 83 KPCGHPGDTPFGSFRLAVGSQFEFGAKVVYTCDDGYQLLGEIDYRECGADG-WINDIPLC 141
Query: 303 NTLKCLPRVCPFAGILENGAVRYTT-FEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPD 479
+KCLP G + +GA + + + F CN GF ++G C+E G WS +
Sbjct: 142 EVVKCLPVTELENGRIVSGAAETDQEYYFGQVVRFECNSGFKIEGHKEIHCSENGLWSNE 201
Query: 480 LXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGN 659
++V KP+ N Y K +P+ G CT G
Sbjct: 202 KPRCVEILCTPPRVENGDGINV-KPVYKENERYHYKCKHGYVPKE----RGDAVCTGSG- 255
Query: 660 WTELPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGC-HDTYTLDGPEEVECNKFG 836
W+ P C+E +C P NG + P + + D+ Y C + Y + G +C G
Sbjct: 256 WSSQPFCEEKRCS-PPYILNG-IYTPHRIIHRSDDEIRYECNYGFYPVTGSTVSKCTPTG 313
Query: 837 NWSAQPSC 860
W P C
Sbjct: 314 -WIPVPRC 320
Score = 67.4 bits (163), Expect = 1e-11
Identities = 60/228 (26%), Positives = 93/228 (40%), Gaps = 7/228 (3%)
Frame = +3
Query: 201 YAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLK--CLPRVCPFAGILENGAVRY- 371
Y G + Y C+PGY + G I + +C G W + C + C G G+ R
Sbjct: 42 YPEGTQATYKCRPGYRTLGTIVK-VCK-NGKWVASNPSRICRKKPCGHPGDTPFGSFRLA 99
Query: 372 --TTFEYPNTISFTCNRGFSLKG-ANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLS 542
+ FE+ + +TC+ G+ L G + +C +G W D+ + ++
Sbjct: 100 VGSQFEFGAKVVYTCDDGYQLLGEIDYRECGADG-WINDIPLCEVVKCLPVTELENGRIV 158
Query: 543 VYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWT-ELPECKEVKCPFPSRPEN 719
+G FEC + G+ I C+E+G W+ E P C E+ C P R EN
Sbjct: 159 SGAAETDQEYYFGQVVRFECNSGFKIEGHKEIHCSENGLWSNEKPRCVEILCT-PPRVEN 217
Query: 720 GFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQPSCK 863
G K V ++ Y C Y + C G WS+QP C+
Sbjct: 218 G-DGINVKPVYKENERYHYKCKHGYVPKERGDAVCTGSG-WSSQPFCE 263
Score = 64.3 bits (155), Expect = 9e-11
Identities = 54/227 (23%), Positives = 88/227 (37%), Gaps = 2/227 (0%)
Frame = +3
Query: 195 SSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVC--PFAGILENGAVR 368
SS+ G Y C G+ R I G W +C+ C P + L ++
Sbjct: 894 SSHEHGTTFSYVCDDGF--RIPEENRITCYMGKWSTPP-RCVGLPCGPPPSIPLGTVSLE 950
Query: 369 YTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKLSVY 548
++++ +++ C+ GF + G C E GKWS K ++
Sbjct: 951 LESYQHGEEVTYHCSTGFGIDGPAFIIC-EGGKWSDPPKCIKTDCDVLPT----VKNAII 1005
Query: 549 KPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTELPECKEVKCPFPSRPENGFV 728
+ + + G + F C + M G+ T+TC + W P CK+ C P N +
Sbjct: 1006 RGKSKKSYRTGEQVTFRCQSPYQMNGSDTVTCV-NSRWIGQPVCKDNSCVDPPHVPNATI 1064
Query: 729 NYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQPSCKAS 869
K + D+ Y C+ L G EV C G W+ +P C+ S
Sbjct: 1065 VTRTKNKYLHGDRVRYECNKPLELFGQVEVMCEN-GIWTEKPKCRDS 1110
Score = 61.6 bits (148), Expect = 6e-10
Identities = 62/241 (25%), Positives = 97/241 (39%), Gaps = 17/241 (7%)
Frame = +3
Query: 201 YAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLP-RVCPFAGI-LENGAVRYT 374
Y G+ + C GY + G C G P KC+ + C + I ++NG + +
Sbjct: 406 YVQGQSLKVQCYNGYSLQNGQDTMTCTENGWSP--PPKCIRIKTCSASDIHIDNGFLSES 463
Query: 375 TFEYP--NTISFTCNRGFSLKG---ANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAKL 539
+ Y S+ C +G+ + S C + G WSP K +
Sbjct: 464 SSIYALNRETSYRCKQGYVTNTGEISGSITCLQNG-WSPQ-----------PSCIKSCDM 511
Query: 540 SVYKPLAGNNSL----YGGKAVFECL---PQHAMFGNGTITCTEHGNWTELPECKEVKCP 698
V++ N+ K +ECL G+ITCT +G W++ P C E +C
Sbjct: 512 PVFENSITKNTRTWFKLNDKLDYECLVGFENEYKHTKGSITCTYYG-WSDTPSCYERECS 570
Query: 699 FPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQPSCK---AS 869
P+ V+ P K+ D + CH + + GP+ V+C FG P+CK AS
Sbjct: 571 VPTLDRKLVVS-PRKEKYRVGDLLEFSCHSGHRV-GPDSVQCYHFGWSPGFPTCKGQVAS 628
Query: 870 C 872
C
Sbjct: 629 C 629
Score = 59.7 bits (143), Expect = 2e-09
Identities = 64/259 (24%), Positives = 104/259 (39%), Gaps = 23/259 (8%)
Frame = +3
Query: 177 VVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCLPRVCPFAGILEN 356
+ P + + +EI Y C G+ G C TG P+ +C + C F +
Sbjct: 276 IYTPHRIIHRSDDEIRYECNYGFYPVTGSTVSKCTPTGWIPVP--RCTLKPCEFPQF-KY 332
Query: 357 GAVRYTTFEYPN-------TISFTCNRGFSLKGANS---AKCTEEGKWSPDLXXXXXXXX 506
G + Y PN S+ C+ GFS S +CT +G W P++
Sbjct: 333 GRLYYEESLRPNFPVSIGNKYSYKCDNGFSPPSGYSWDYLRCTAQG-WEPEV-------- 383
Query: 507 XXXXXXKFAKLSVYKPLAGNNSLY-------GGKAVFECLPQHAMF-GNGTITCTEHGNW 662
+ V+ + +S Y G +C +++ G T+TCTE+G W
Sbjct: 384 ------PCVRKCVFHYVENGDSAYWEKVYVQGQSLKVQCYNGYSLQNGQDTMTCTENG-W 436
Query: 663 TELPECKEVKCPFPS--RPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPE---EVECN 827
+ P+C +K S +NGF++ + + + +Y C Y + E + C
Sbjct: 437 SPPPKCIRIKTCSASDIHIDNGFLS-ESSSIYALNRETSYRCKQGYVTNTGEISGSITCL 495
Query: 828 KFGNWSAQPSCKASCKLSV 884
+ G WS QPSC SC + V
Sbjct: 496 QNG-WSPQPSCIKSCDMPV 513
Score = 52.4 bits (124), Expect = 4e-07
Identities = 72/291 (24%), Positives = 106/291 (35%), Gaps = 25/291 (8%)
Frame = +3
Query: 141 RTCPKPEELPFAVVVPLKSSYAPGEEIVYTCQPGYVSRGGIRRFICPLTGLWPINTLKCL 320
R C P VV P K Y G+ + ++C G+ R G C G W C
Sbjct: 567 RECSVPTLDRKLVVSPRKEKYRVGDLLEFSCHSGH--RVGPDSVQCYHFG-WSPGFPTCK 623
Query: 321 PRVCPFAGILE------NGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSP-- 476
+V A LE NGA + + + + + C F LKG N +C +G W+
Sbjct: 624 GQVASCAPPLEILNGEINGA-KKVEYSHGEVVKYDCKPRFLLKGPNKIQCV-DGNWTTLP 681
Query: 477 -DLXXXXXXXXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEH 653
+ AK SV P +G F C M G+G+++C
Sbjct: 682 VCIEEERTCGDIPELEHGSAKCSV-PPYH-----HGDSVEFICEENFTMIGHGSVSCIS- 734
Query: 654 GNWTELPECKEV----KCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVE 821
G WT+LP+C KC + P + Y C D + +
Sbjct: 735 GKWTQLPKCVATDQLEKCRVLKSTGIEAIK-PKLTEFTHNSTMDYKCRDKQEYERSICIN 793
Query: 822 CNKFGNWSAQPSC--KASC-------KLSVKRATVIY-EGERVNI--QDKF 938
G W +P+C K SC V TV Y +GE++++ QD +
Sbjct: 794 ----GKWDPEPNCTSKTSCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNY 840
Score = 47.0 bits (110), Expect = 1e-05
Identities = 59/230 (25%), Positives = 83/230 (35%), Gaps = 8/230 (3%)
Frame = +3
Query: 195 SSYAPGEEIVYTCQPGYVSRGG-IRRFICPLTGLWPINTLKCLPRVCPFAGILENGAVRY 371
S YA E Y C+ GYV+ G I I L W C+ + C + EN +
Sbjct: 465 SIYALNRETSYRCKQGYVTNTGEISGSITCLQNGWSPQP-SCI-KSCDMP-VFENSITKN 521
Query: 372 TT--FEYPNTISFTCNRGFSLKGAN---SAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAK 536
T F+ + + + C GF + + S CT G WS K
Sbjct: 522 TRTWFKLNDKLDYECLVGFENEYKHTKGSITCTYYG-WSDTPSCYERECSVPTLDRKL-- 578
Query: 537 LSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTELPECKE--VKCPFPSR 710
V P + G F C H + G ++ C G P CK C P
Sbjct: 579 --VVSPRKEKYRV-GDLLEFSCHSGHRV-GPDSVQCYHFGWSPGFPTCKGQVASCAPPLE 634
Query: 711 PENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVECNKFGNWSAQPSC 860
NG +N K + + Y C + L GP +++C GNW+ P C
Sbjct: 635 ILNGEINGAKKVEYSHGEVVKYDCKPRFLLKGPNKIQCVD-GNWTTLPVC 683
>gi|6677655|ref|NP_033607.1| (NM_009581) zona pellucida 3 receptor
[Mus musculus]
Length = 579
Score = 74.7 bits (182), Expect = 7e-14
Identities = 61/264 (23%), Positives = 103/264 (38%), Gaps = 19/264 (7%)
Frame = +3
Query: 201 YAPGEEIVYTCQPGYVSRGGIRRFICPLT----GLWPINTLKCLPRVCPFA----GILEN 356
Y G ++Y C P + G +C + G+W + C VC G L
Sbjct: 177 YTFGSVVIYNCDPTFTLLGNAS-IVCTVVNRTVGVWRPHPPACQKIVCHRPQIPKGYLAP 235
Query: 357 GAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXXXXXXXXXXKFAK 536
G ++ + Y + + C +GF L+G++ C G+W P + +A
Sbjct: 236 GFRQF--YAYRDALEIRCKKGFILRGSSVIHCEANGEWFPSIPTCEPNGCTNIPDISYAS 293
Query: 537 LSVYKPLAGNNSLY--GGKAVFECLPQHAMFGNG--TITCTEHGNWTELPECKEVKCPFP 704
YK N ++ G K ++C P + N T+TC E+ W+ C+ + CP P
Sbjct: 294 WEGYKFPLRNFEVFEIGAKLKYQCKPGYRASLNDPQTVTCQENLTWSSTNGCERICCPTP 353
Query: 705 SRPENGFV----NYPAKQVLYYQDKATYGCHD-TYTLDGPEEVECNKFGNWS-AQPSCKA 866
+ V ++ + Y D Y C++ +Y + C G W A PSC+A
Sbjct: 354 DMEKIKIVSERRDFTGTCIYAYGDYVFYICNEGSYPMSTDGRSSCQADGKWDPAIPSCQA 413
Query: 867 SCKLSVKRATVIYEG-ERVNIQDK 935
L + A + N+ +K
Sbjct: 414 DSGLQNRLALFTFPNISETNVTNK 437
Score = 52.4 bits (124), Expect = 4e-07
Identities = 45/186 (24%), Positives = 65/186 (34%), Gaps = 8/186 (4%)
Frame = +3
Query: 321 PRVCPFAGILENGAVRYTTFEYPNTISFTCNRGFSLKGANSAKCTEEGKWSPDLXXXXXX 500
P + PFA N TTF + +TC+ GF ++ C E G W
Sbjct: 37 PPLLPFASPT-NQLYESTTFPSGTVLKYTCHHGFKRVNSSHLSCDENGSW------VYST 89
Query: 501 XXXXXXXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHG---NWTE- 668
+L K ++ L G F C + + G+ T C G +W++
Sbjct: 90 FCARKRCKNPGELVNGKVEIPSDLLVGSIIEFSCSKGYLLIGSATSRCEVQGKGVDWSDS 149
Query: 669 LPECKEVKCPFPSRPENGFVNYPAKQVLYYQDKATYGCHDTYTLDGPEEVEC----NKFG 836
LPEC C P NG + + + Y C T+TL G + C G
Sbjct: 150 LPECVIATCEPPPPISNGKHSGRDDDLYTFGSVVIYNCDPTFTLLGNASIVCTVVNRTVG 209
Query: 837 NWSAQP 854
W P
Sbjct: 210 VWRPHP 215
>gi|7656969|ref|NP_056595.1| (NM_015780) complement factor H-related
protein [Mus musculus]
Length = 343
Score = 70.5 bits (171), Expect = 1e-12
Identities = 75/268 (27%), Positives = 114/268 (41%), Gaps = 23/268 (8%)
Frame = +3
Query: 195 SSYAPGEEIVYTCQPGYVSRGGI--RRFICPLTGLWPINTLKCLPRVCPFAGILENGAVR 368
SS G+ + Y+C+ + S R C +G P T KCL R+C F +ENG
Sbjct: 48 SSVLSGKILYYSCEYNFASPSNSFWTRITCTESGWSP--TPKCL-RLC-FFPFVENGNST 103
Query: 369 YT--TFEYPNTISFTCNRGFSLKGANSA-KCTEEGKWS--PDLXXXXXXXX------XXX 515
+ T + + CN+G+SL+ S C EEG WS P
Sbjct: 104 SSGQTHVEGDIVQVVCNQGYSLQNNQSTITCAEEG-WSITPKCISTNPTGKCGPPPPIDN 162
Query: 516 XXXKFAKLSVYKPLAGNNSLYGGKAVFECLPQHAMFGNGTITCTEHGNWTELPEC--KEV 689
L VY L+ ++C + + GN TITC +G W+E P C
Sbjct: 163 GDITSLSLPVYASLS--------SVEYQCQKYYLLKGNKTITC-RNGKWSEPPTCIYPTG 213
Query: 690 KCPFPSRPENGFVNYPAKQVLYYQ--DKATYGCHDTYTLDGPEEVECNKFGNWSAQPSCK 863
KC P +NG + + +L Y+ Y C + Y L G + + C G WS P+C
Sbjct: 214 KCGPPPPIDNGDIT--SLSLLEYEPLSSVEYQCQNYYVLKGKKTITCRN-GKWSEPPTCL 270
Query: 864 ASCKLS---VKRATVIY---EGERVNIQ 929
++C +S ++R ++ + E+V IQ
Sbjct: 271 SACVISEAIMERHNILLRWRQSEKVYIQ 298
Database: RefSeq (Mus Musculus/Amino Acid)
Posted date: Jul 1, 2003 6:07 AM
Number of letters in database: 7,155,815
Number of sequences in database: 15,330
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15658206
Number of Sequences: 15330
Number of extensions: 411741
Number of successful extensions: 1670
Number of sequences better than 10.0: 53
Number of HSP's better than 10.0 without gapping: 1185
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1434
length of query: 334
length of database: 7,155,815
effective HSP length: 47
effective length of query: 287
effective length of database: 6,435,305
effective search space: 1846932535
effective search space used: 1846932535
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)