Search to RefSeq (Human) database
Query= 20030531C-000083 (20030531C-000083) 20030531C-000083
(1174 letters)
Database: RefSeq (Homo Sapiens/Amino Acid)
19,244 sequences; 10,046,356 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|4507651|ref|NP_003281.1| (NM_003290) tropomyosin 4 [Homo sap... 290 1e-78
Alignment gi|24119203|ref|NP_705935.1| (NM_153649) tropomyosin 3 [Homo sa... 205 4e-53
Alignment gi|4507649|ref|NP_003280.1| (NM_003289) tropomyosin 2 (beta) [H... 192 4e-49
Alignment gi|22748619|ref|NP_689476.1| (NM_152263) tropomyosin 3 [Homo sa... 173 2e-43
Alignment gi|27597085|ref|NP_000357.3| (NM_000366) tropomyosin 1 (alpha) ... 160 2e-39
Alignment gi|31543429|ref|NP_002696.2| (NM_002705) periplakin [Homo sapiens] 41 0.002
Alignment gi|15149461|ref|NP_149129.1| (NM_033138) caldesmon 1 isoform 1;... 35 0.13
Alignment gi|13376858|ref|NP_079520.1| (NM_025244) testis specific, 10 [H... 35 0.13
Alignment gi|4506751|ref|NP_002947.1| (NM_002956) restin (Reed-Steinberg ... 33 0.28
Alignment gi|13435161|ref|NP_079489.1| (NM_025213) spectrin, beta, non-er... 33 0.48
>gi|4507651|ref|NP_003281.1| (NM_003290) tropomyosin 4 [Homo sapiens]
Length = 248
Score = 290 bits (742), Expect = 1e-78
Identities = 163/248 (65%), Positives = 163/248 (65%)
Frame = +1
Query: 277 MAGLNSLEAVKRKIXXXXXXXXXXXXXXXGLQRELDGERERREKAEGDVAALNRRIQLVE 456
MAGLNSLEAVKRKI GLQRELDGERERREKAEGDVAALNRRIQLVE
Sbjct: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60
Query: 457 EELDRAQERXXXXXXXXXXXXXXXXXXXRGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE 636
EELDRAQER RGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE 120
Query: 637 EADRKYEEVARKLVIXXXXXXXXXXXXXVSELKCGDLEEELKNVTNNLXXXXXXXXXXXX 816
EADRKYEEVARKLVI VSELKCGDLEEELKNVTNNL
Sbjct: 121 EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSE 180
Query: 817 XXXXXXXXXXXXSDKLKXXXXXXXXXXXXXXKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 996
SDKLK KLEKTIDDLEEKLAQAKEENVGLHQTLDQ
Sbjct: 181 KEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
Query: 997 TLNELNCI 1020
TLNELNCI
Sbjct: 241 TLNELNCI 248
>gi|24119203|ref|NP_705935.1| (NM_153649) tropomyosin 3 [Homo sapiens]
Length = 248
Score = 205 bits (522), Expect = 4e-53
Identities = 116/246 (47%), Positives = 143/246 (57%)
Frame = +1
Query: 277 MAGLNSLEAVKRKIXXXXXXXXXXXXXXXGLQRELDGERERREKAEGDVAALNRRIQLVE 456
MAG+ ++EAVKRKI LQRE++GER RE+AE +VA+LNRRIQLVE
Sbjct: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
Query: 457 EELDRAQERXXXXXXXXXXXXXXXXXXXRGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE 636
EELDRAQER RGMKVIENRA+KDEEKME+QE+QLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 637 EADRKYEEVARKLVIXXXXXXXXXXXXXVSELKCGDLEEELKNVTNNLXXXXXXXXXXXX 816
EADRKYEEVARKLVI ++E +C +++E+++ + NL
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
Query: 817 XXXXXXXXXXXXSDKLKXXXXXXXXXXXXXXKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 996
+DKLK KLEKTIDDLE+KL KEE++ + LDQ
Sbjct: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
Query: 997 TLNELN 1014
TL +LN
Sbjct: 241 TLLDLN 246
>gi|4507649|ref|NP_003280.1| (NM_003289) tropomyosin 2 (beta) [Homo
sapiens]
Length = 284
Score = 192 bits (488), Expect = 4e-49
Identities = 112/239 (46%), Positives = 131/239 (53%)
Frame = +1
Query: 298 EAVKRKIXXXXXXXXXXXXXXXGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 477
+A+++K+ Q +L+ ++ AE DVA+LNRRIQLVEEELDRAQ
Sbjct: 44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
Query: 478 ERXXXXXXXXXXXXXXXXXXXRGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 657
ER RGMKVIENRAMKDEEKME+QEMQLKEAKHIAE++DRKYE
Sbjct: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
Query: 658 EVARKLVIXXXXXXXXXXXXXVSELKCGDLEEELKNVTNNLXXXXXXXXXXXXXXXXXXX 837
EVARKLVI V+E + LEEEL+ + L
Sbjct: 164 EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE 223
Query: 838 XXXXXSDKLKXXXXXXXXXXXXXXKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 1014
+KLK KLEKTIDDLEE LA AKEENV +HQTLDQTL ELN
Sbjct: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 282
>gi|22748619|ref|NP_689476.1| (NM_152263) tropomyosin 3 [Homo sapiens]
Length = 243
Score = 173 bits (438), Expect = 2e-43
Identities = 99/242 (40%), Positives = 128/242 (51%)
Frame = +1
Query: 295 LEAVKRKIXXXXXXXXXXXXXXXGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 474
+EA+K+K+ + E ER ++ E ++AA+ ++++ E+ELDRA
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDRA 61
Query: 475 QERXXXXXXXXXXXXXXXXXXXRGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 654
QER RGMKVIENRA+KDEEKME+QE+QLKEAKHIAEEADRKY
Sbjct: 62 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 121
Query: 655 EEVARKLVIXXXXXXXXXXXXXVSELKCGDLEEELKNVTNNLXXXXXXXXXXXXXXXXXX 834
EEVARKLVI ++E KC +LEEELKNVTNNL
Sbjct: 122 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 181
Query: 835 XXXXXXSDKLKXXXXXXXXXXXXXXKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 1014
+DKLK KLEKTIDDLE++L K + + + LD LN++
Sbjct: 182 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMT 241
Query: 1015 CI 1020
I
Sbjct: 242 SI 243
>gi|27597085|ref|NP_000357.3| (NM_000366) tropomyosin 1 (alpha) [Homo
sapiens]
Length = 284
Score = 160 bits (405), Expect = 2e-39
Identities = 97/241 (40%), Positives = 124/241 (51%)
Frame = +1
Query: 289 NSLEAVKRKIXXXXXXXXXXXXXXXGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 468
+ L ++++K+ Q +L+ ++ AE DVA+LNRRIQLVEEELD
Sbjct: 41 DELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD 100
Query: 469 RAQERXXXXXXXXXXXXXXXXXXXRGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 648
RAQER RGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADR
Sbjct: 101 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 160
Query: 649 KYEEVARKLVIXXXXXXXXXXXXXVSELKCGDLEEELKNVTNNLXXXXXXXXXXXXXXXX 828
KYEEVARKLVI +SE + LEE+L+ + L
Sbjct: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR 220
Query: 829 XXXXXXXXSDKLKXXXXXXXXXXXXXXKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 1008
SDKLK KLEK+IDDLE++L K + + + LD LN+
Sbjct: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
Query: 1009 L 1011
+
Sbjct: 281 M 281
>gi|31543429|ref|NP_002696.2| (NM_002705) periplakin [Homo sapiens]
Length = 1756
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/193 (22%), Positives = 79/193 (40%), Gaps = 4/193 (2%)
Frame = +1
Query: 214 QEQSRAERPPLPAARCVRLRAMAGLNSLEAVKRKIXXXXXXXXXXXXXXXGLQR---ELD 384
QE R E P +R A A S++ R+I L+R EL+
Sbjct: 1353 QEVVRYEEEP-----GLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEELE 1407
Query: 385 GERERREKAEGDVAALNRRIQLVEEELDRAQERXXXXXXXXXXXXXXXXXXXRGMKVIEN 564
ER+ R +AE +V L +R+ +E+E A+E+ KV+
Sbjct: 1408 RERQARREAEREVQRLQQRLAALEQEEAEAREKVTHT-----------------QKVVLQ 1450
Query: 565 RAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVIXXXXXXXXXXXXXVS-ELKCG 741
+ + + + +QL+E +H + + + E + RKL S +++ G
Sbjct: 1451 QDPQQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKG 1510
Query: 742 DLEEELKNVTNNL 780
D E+E++ + ++L
Sbjct: 1511 DTEQEIQRLKSSL 1523
>gi|15149461|ref|NP_149129.1| (NM_033138) caldesmon 1 isoform 1;
H-CAD; L-CAD [Homo sapiens]
Length = 793
Score = 34.7 bits (78), Expect = 0.13
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 2/99 (2%)
Frame = +1
Query: 379 LDGERERREKAEGDVAALNRRIQLVEEELDRAQERXXXXXXXXXXXXXXXXXXXRGMKVI 558
L+ E R KAE D + R ++ EE AQER
Sbjct: 272 LEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAE----- 326
Query: 559 ENRAMKDEEKMEIQEMQ--LKEAKHIAEEADRKYEEVAR 669
E + +K+EEK +E Q +E K AEE R EE R
Sbjct: 327 ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKR 365
Score = 33.9 bits (76), Expect = 0.21
Identities = 40/161 (24%), Positives = 62/161 (37%), Gaps = 7/161 (4%)
Frame = +1
Query: 214 QEQSRAERPPLPAARCVRLRAMAGLNSLEAVKRKIXXXXXXXXXXXXXXXGLQRELDGER 393
+E++ AER L A R++A E K+ +R ER
Sbjct: 262 KERAEAERARLEAEERERIKA-------EQDKKIADERARIEAEEKAAAQERERREAEER 314
Query: 394 ERREKAEGDVAALNRRIQLVEEELDRAQERXXXXXXXXXXXXXXXXXXXRGMKVIENR-- 567
ER + E A +RI+ EEE A+ER + E R
Sbjct: 315 ERMREEEKRAAEERQRIK--EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQR 372
Query: 568 -AMKDEEKMEIQEM----QLKEAKHIAEEADRKYEEVARKL 675
++EEK +++E QL+E K +E K E+V +K+
Sbjct: 373 ARAEEEEKAKVEEQKRNKQLEEKKRAMQETKIKGEKVEQKI 413
>gi|13376858|ref|NP_079520.1| (NM_025244) testis specific, 10 [Homo
sapiens]
Length = 698
Score = 34.7 bits (78), Expect = 0.13
Identities = 19/36 (52%), Positives = 26/36 (71%)
Frame = +1
Query: 928 DDLEEKLAQAKEENVGLHQTLDQTLNELNCI*PKQK 1035
D+L+E+ A+AK+EN L + L+ T NELN I KQK
Sbjct: 355 DNLQEQFAKAKQENQALSKKLNDTHNELNDI--KQK 388
>gi|4506751|ref|NP_002947.1| (NM_002956) restin (Reed-Steinberg
cell-expressed intermediate filament-associated protein);
cytoplasmic linker 1 [Homo sapiens]
Length = 1427
Score = 33.5 bits (75), Expect = 0.28
Identities = 18/52 (34%), Positives = 35/52 (66%)
Frame = +1
Query: 913 LEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI*PKQKSLVPSETPELR 1068
LEK + L+EK A+A EE V + +++ +T+N+L+ +Q +++ S+ +LR
Sbjct: 838 LEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQK-EEQFNMLSSDLEKLR 888
Score = 32.0 bits (71), Expect = 0.81
Identities = 15/28 (53%), Positives = 21/28 (74%)
Frame = +1
Query: 913 LEKTIDDLEEKLAQAKEENVGLHQTLDQ 996
L+KT+ D E+KL A+EEN GL Q L++
Sbjct: 1036 LQKTLLDTEDKLKGAREENSGLLQELEE 1063
>gi|13435161|ref|NP_079489.1| (NM_025213) spectrin, beta,
non-erythrocytic 4; spectrin beta 4 [Homo sapiens]
Length = 2559
Score = 32.7 bits (73), Expect = 0.48
Identities = 18/40 (45%), Positives = 19/40 (47%)
Frame = -3
Query: 287 RPAMARRRTQRAAGSGGRSARLCSCKSCSSRAPAPEPFPT 168
RP RR R G GG S R S + APAP P PT
Sbjct: 2372 RPKPRRRPRPREGGEGGGSRRSRSAPAQGGSAPAPPPPPT 2411
Database: RefSeq (Homo Sapiens/Amino Acid)
Posted date: Jul 1, 2003 6:07 AM
Number of letters in database: 10,046,356
Number of sequences in database: 19,244
Lambda K H
0.315 0.133 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17012468
Number of Sequences: 19244
Number of extensions: 339911
Number of successful extensions: 2056
Number of sequences better than 10.0: 48
Number of HSP's better than 10.0 without gapping: 1257
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 358
Number of HSP's gapped (non-prelim): 1719
length of query: 391
length of database: 10,046,356
effective HSP length: 53
effective length of query: 337
effective length of database: 9,026,424
effective search space: 3041904888
effective search space used: 3041904888
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search to RefSeq (Mouse) database
Query= 20030531C-000083 (20030531C-000083) 20030531C-000083
(1174 letters)
Database: RefSeq (Mus Musculus/Amino Acid)
15,330 sequences; 7,155,815 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|31560030|ref|NP_077745.2| (NM_024427) tropomyosin 1, alpha; ... 203 1e-52
Alignment gi|11875203|ref|NP_033442.2| (NM_009416) tropomyosin 2, beta [M... 185 3e-47
Alignment gi|13928666|ref|NP_071709.1| (NM_022314) tropomyosin 3, gamma; ... 182 2e-46
Alignment gi|22218336|ref|NP_032935.1| (NM_008909) periplakin; 195-kD pro... 38 0.010
Alignment gi|30794220|ref|NP_115999.1| (NM_032610) spectrin beta 4; beta-... 33 0.33
Alignment gi|29243994|ref|NP_808284.1| (NM_177616) hypothetical protein 4... 32 0.44
Alignment gi|31982705|ref|NP_064368.2| (NM_019984) transglutaminase 1, K ... 31 0.97
Alignment gi|19745146|ref|NP_034211.1| (NM_010081) dystonin isoform e; bu... 31 0.97
Alignment gi|6754774|ref|NP_034986.1| (NM_010856) myosin, heavy polypepti... 30 1.7
Alignment gi|6677759|ref|NP_033097.1| (NM_009071) Rho-associated coiled-c... 30 1.7
>gi|31560030|ref|NP_077745.2| (NM_024427) tropomyosin 1, alpha; alpha
tropomyosin [Mus musculus]
Length = 284
Score = 203 bits (516), Expect = 1e-52
Identities = 117/242 (48%), Positives = 137/242 (56%)
Frame = +1
Query: 289 NSLEAVKRKIXXXXXXXXXXXXXXXGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 468
+ L ++++K+ Q +L+ ++ AE DVA+LNRRIQLVEEELD
Sbjct: 41 DELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD 100
Query: 469 RAQERXXXXXXXXXXXXXXXXXXXRGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 648
RAQER RGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADR
Sbjct: 101 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 160
Query: 649 KYEEVARKLVIXXXXXXXXXXXXXVSELKCGDLEEELKNVTNNLXXXXXXXXXXXXXXXX 828
KYEEVARKLVI +SE KC +LEEELK VTNNL
Sbjct: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDK 220
Query: 829 XXXXXXXXSDKLKXXXXXXXXXXXXXXKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 1008
SDKLK KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL E
Sbjct: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
Query: 1009 LN 1014
LN
Sbjct: 281 LN 282
>gi|11875203|ref|NP_033442.2| (NM_009416) tropomyosin 2, beta [Mus
musculus]
Length = 284
Score = 185 bits (470), Expect = 3e-47
Identities = 106/241 (43%), Positives = 130/241 (52%)
Frame = +1
Query: 298 EAVKRKIXXXXXXXXXXXXXXXGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 477
+A+++K+ Q +L+ ++ AE DVA+LNRRIQLVEEELDRAQ
Sbjct: 44 QALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
Query: 478 ERXXXXXXXXXXXXXXXXXXXRGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 657
ER RGMKVIENRAMKDEEKME+QEMQLKEAKHIAE++DRKYE
Sbjct: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
Query: 658 EVARKLVIXXXXXXXXXXXXXVSELKCGDLEEELKNVTNNLXXXXXXXXXXXXXXXXXXX 837
EVARKLVI V+E KCGDLEEELK VTNNL
Sbjct: 164 EVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEE 223
Query: 838 XXXXXSDKLKXXXXXXXXXXXXXXKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNC 1017
+KLK KLEKTIDDLE+++ K + + + LD LN++
Sbjct: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITS 283
Query: 1018 I 1020
+
Sbjct: 284 L 284
>gi|13928666|ref|NP_071709.1| (NM_022314) tropomyosin 3, gamma;
skalphaTM.2; tropomyosin 5 [Mus musculus]
Length = 284
Score = 182 bits (463), Expect = 2e-46
Identities = 106/244 (43%), Positives = 130/244 (52%)
Frame = +1
Query: 289 NSLEAVKRKIXXXXXXXXXXXXXXXGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 468
+ L +++K+ Q +L+ ++ AE +VA+LNRRIQLVEEELD
Sbjct: 41 DELATMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELD 100
Query: 469 RAQERXXXXXXXXXXXXXXXXXXXRGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 648
RAQER RGMKVIENRA+KDEEKME+QE+QLKEAKHIAEEADR
Sbjct: 101 RAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR 160
Query: 649 KYEEVARKLVIXXXXXXXXXXXXXVSELKCGDLEEELKNVTNNLXXXXXXXXXXXXXXXX 828
KYEEVARKLVI ++E KC +LEEELKNVTNNL
Sbjct: 161 KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDK 220
Query: 829 XXXXXXXXSDKLKXXXXXXXXXXXXXXKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 1008
+DKLK KLEKTIDDLE++L K + + LD LN+
Sbjct: 221 YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISDELDHALND 280
Query: 1009 LNCI 1020
+ I
Sbjct: 281 MTSI 284
>gi|22218336|ref|NP_032935.1| (NM_008909) periplakin; 195-kD protein;
195kDa protein [Mus musculus]
Length = 1755
Score = 37.7 bits (86), Expect = 0.010
Identities = 38/177 (21%), Positives = 71/177 (39%), Gaps = 4/177 (2%)
Frame = +1
Query: 262 VRLRAMAGLNSLEAVKRKIXXXXXXXXXXXXXXXGLQR---ELDGERERREKAEGDVAAL 432
+R A NS++A R+I L+R EL+ ER+ R AE +V L
Sbjct: 1363 LRAEVTAFTNSIDAELRQIDKLHVELRRLQHRRAELERQLEELERERQARRAAELEVQRL 1422
Query: 433 NRRIQLVEEELDRAQERXXXXXXXXXXXXXXXXXXXRGMKVIENRAMKDEEKMEIQEMQL 612
+R+ +E+E + E+ KV+ + + + + QL
Sbjct: 1423 QQRLAALEQEEAKTGEKVTHT-----------------QKVVLQQDPQQTREHALLRAQL 1465
Query: 613 KEAKHIAEEADRKYEEVARKLVIXXXXXXXXXXXXXVS-ELKCGDLEEELKNVTNNL 780
+E +H + + + E + RKL S +++ GD E+E++ + +L
Sbjct: 1466 EEERHRRQLLEGELEPLRRKLAALEKAEIKEKVVFSESVQVEKGDTEQEIQRLKKSL 1522
Score = 28.9 bits (63), Expect = 4.8
Identities = 22/102 (21%), Positives = 46/102 (44%)
Frame = +1
Query: 367 LQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERXXXXXXXXXXXXXXXXXXXRG 546
L+ +L E++++ EG+ A+ +I+ EEEL AQ+R
Sbjct: 1309 LRIQLSEEQKKQVDLEGERASQEEKIKRKEEEL--AQQRKERVVRQEVVQYEDEPDLRAE 1366
Query: 547 MKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARK 672
+ N + +++ ++L+ +H E +R+ EE+ R+
Sbjct: 1367 VTAFTNSIDAELRQIDKLHVELRRLQHRRAELERQLEELERE 1408
>gi|30794220|ref|NP_115999.1| (NM_032610) spectrin beta 4;
beta-spectrin 4; quivering; lumbosacral neuroaxonal
dystrophy; neuroaxonal dystrophy [Mus musculus]
Length = 2561
Score = 32.7 bits (73), Expect = 0.33
Identities = 18/40 (45%), Positives = 19/40 (47%)
Frame = -3
Query: 287 RPAMARRRTQRAAGSGGRSARLCSCKSCSSRAPAPEPFPT 168
RP RR R G GG S R S + APAP P PT
Sbjct: 2374 RPKPRRRPRPREGGEGGGSRRSRSAPAQGGSAPAPPPPPT 2413
>gi|29243994|ref|NP_808284.1| (NM_177616) hypothetical protein
4930562D19 [Mus musculus]
Length = 616
Score = 32.3 bits (72), Expect = 0.44
Identities = 20/101 (19%), Positives = 45/101 (43%)
Frame = +1
Query: 373 RELDGERERREKAEGDVAALNRRIQLVEEELDRAQERXXXXXXXXXXXXXXXXXXXRGMK 552
++L+ E ERR AE V L ++QL+ LD A ++ R +
Sbjct: 284 QQLEEEGERRAAAERQVQQLEEQVQLLAGRLDGASQQIRWASTELDKEKARVDSMVRHQE 343
Query: 553 VIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKL 675
++ + ++++ + + +E + +EA+ + E+ +L
Sbjct: 344 SLQAKQRTLLQQLDCLDQEREELRGSLDEAEAQRSELEEQL 384
>gi|31982705|ref|NP_064368.2| (NM_019984) transglutaminase 1, K
polypeptide;
protein-glutamine-gamma-glutamyltransferase;
transglutaminase type 1; TG K; TGase 1; K polypeptide
[Mus musculus]
Length = 815
Score = 31.2 bits (69), Expect = 0.97
Identities = 21/53 (39%), Positives = 23/53 (42%), Gaps = 5/53 (9%)
Frame = -3
Query: 320 WILRFTASRELRPAMARRRTQRAAGSGGRS--ARLCSCKSCSSRAP---APEP 177
W T S E P R R+ GGRS AR C C SC +R PEP
Sbjct: 16 WQPPTTPSPEPEPEPEPDRRSRSRRGGGRSFWARCCGCCSCGNRGDDDWGPEP 68
>gi|19745146|ref|NP_034211.1| (NM_010081) dystonin isoform e; bullous
pemphigoid antigen 1; dystonia musculorum [Mus musculus]
Length = 2611
Score = 31.2 bits (69), Expect = 0.97
Identities = 23/104 (22%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Frame = +1
Query: 367 LQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERXXXXXXXXXXXXXXXXXXXRG 546
LQRE+D AE ++ LN ++ +E D ++ER
Sbjct: 1443 LQREVDRVTRAHALAERNIQCLNSQVHASRDEKDLSEERRRLCQRKSDHLKEEFERSH-- 1500
Query: 547 MKVIENRAMKDEEKMEIQEM--QLKEAKHIAEEADRKYEEVARK 672
++++N + E +IQ++ +L+++ AE +K +E+ R+
Sbjct: 1501 AQLLQNIQAEKENNDKIQKLNKELEKSNECAETLKQKVDELTRQ 1544
>gi|6754774|ref|NP_034986.1| (NM_010856) myosin, heavy polypeptide 6,
cardiac muscle, alpha; myosin heavy chain, cardiac
muscle, adult; alpha myosin; alpha cardiac MHC;
cardiomyopathy, hypertrophic 1 [Mus musculus]
Length = 1938
Score = 30.4 bits (67), Expect = 1.7
Identities = 41/235 (17%), Positives = 84/235 (35%)
Frame = +1
Query: 367 LQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERXXXXXXXXXXXXXXXXXXXRG 546
++ E ++ EK+E RR +L E+ + QE+ R
Sbjct: 854 MKEEFGRVKDALEKSEA------RRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERC 907
Query: 547 MKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVIXXXXXXXXXXXXXVS 726
++I+N+ + + E+ E +L++ + + E K ++ +
Sbjct: 908 DQLIKNKIQLEAKVKEMTE-RLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKV 966
Query: 727 ELKCGDLEEELKNVTNNLXXXXXXXXXXXXXXXXXXXXXXXXSDKLKXXXXXXXXXXXXX 906
E + E ++KN+T + D L+
Sbjct: 967 EKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSK 1026
Query: 907 XKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI*PKQKSLVPSETPELRV 1071
KLE+ +DDLE L Q K+ + L + + +L Q+S++ E +L++
Sbjct: 1027 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL---TQESIMDLENDKLQL 1078
>gi|6677759|ref|NP_033097.1| (NM_009071) Rho-associated coiled-coil
forming kinase 1 [Mus musculus]
Length = 1354
Score = 30.4 bits (67), Expect = 1.7
Identities = 12/39 (30%), Positives = 26/39 (65%)
Frame = +1
Query: 367 LQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 483
++++L ERE REKAE V ++ +++ +L ++Q++
Sbjct: 716 MEKKLKEEREAREKAENRVVETEKQCSMLDVDLKQSQQK 754
Database: RefSeq (Mus Musculus/Amino Acid)
Posted date: Jul 1, 2003 6:07 AM
Number of letters in database: 7,155,815
Number of sequences in database: 15,330
Lambda K H
0.315 0.133 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11964839
Number of Sequences: 15330
Number of extensions: 231107
Number of successful extensions: 1229
Number of sequences better than 10.0: 34
Number of HSP's better than 10.0 without gapping: 811
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 237
Number of HSP's gapped (non-prelim): 1001
length of query: 391
length of database: 7,155,815
effective HSP length: 53
effective length of query: 337
effective length of database: 6,343,325
effective search space: 2137700525
effective search space used: 2137700525
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)