Search to RefSeq (Human) database
Query= 20030826C-005494 (20030826C-005494) 20030826C-005494
(937 letters)
Database: RefSeq (Homo Sapiens/Amino Acid)
19,804 sequences; 10,428,096 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|7427519|ref|NP_005906.2| (NM_005915) minichromosome maintenan... 541 e-154
Alignment gi|33356547|ref|NP_004517.2| (NM_004526) minichromosome maintena... 76 2e-14
Alignment gi|33469968|ref|NP_005907.3| (NM_005916) minichromosome maintena... 76 2e-14
Alignment gi|33469917|ref|NP_877423.1| (NM_182746) minichromosome maintena... 72 5e-13
Alignment gi|33469919|ref|NP_005905.2| (NM_005914) minichromosome maintena... 72 5e-13
Alignment gi|6631095|ref|NP_002379.2| (NM_002388) minichromosome maintenan... 64 9e-11
Alignment gi|23397546|ref|NP_694987.1| (NM_153255) minichromosome maintena... 63 2e-10
Alignment gi|33469922|ref|NP_877577.1| (NM_182776) minichromosome maintena... 56 3e-08
Alignment gi|33469924|ref|NP_877954.1| (NM_182802) minichromosome maintena... 55 5e-08
Alignment gi|19923727|ref|NP_115874.3| (NM_032485) minichromosome maintena... 55 5e-08
>gi|7427519|ref|NP_005906.2| (NM_005915) minichromosome maintenance
protein 6; DNA replication licensing factor MCM6 [Homo
sapiens]
Length = 821
Score = 541 bits (1395), Expect = e-154
Identities = 272/277 (98%), Positives = 275/277 (99%)
Frame = +1
Query: 55 MDLAAAAEPSAGSQHLEVRDEVAEKCQKLFLDFLEEFQNSDGEIKYLQLAEELIRPERNT 234
MDLAAAAEP AGSQHLEVRDEVAEKCQKLFLDFLEEFQ+SDGEIKYLQLAEELIRPERNT
Sbjct: 1 MDLAAAAEPGAGSQHLEVRDEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNT 60
Query: 235 LVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDFYVAFQDLPTR 414
LVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDFYVAFQDLPTR
Sbjct: 61 LVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDFYVAFQDLPTR 120
Query: 415 HKIRELNSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNIC 594
HKIREL SSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNIC
Sbjct: 121 HKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNIC 180
Query: 595 RNPVCANRKRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGD 774
RNPVCANR+RFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGD
Sbjct: 181 RNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGD 240
Query: 775 KCDFTGTLIVVPDVSKLSTPGARAETNSRVNGVDGYE 885
KCDFTGTLIVVPDVSKLSTPGARAETNSRV+GVDGYE
Sbjct: 241 KCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYE 277
>gi|33356547|ref|NP_004517.2| (NM_004526) minichromosome maintenance
protein 2; cdc19; cyclin-like 1; mitotin; cell devision
cycle-like 1; nuclear protein BM28; DNA replication
licensing factor MCM2 [Homo sapiens]
Length = 904
Score = 76.3 bits (186), Expect = 2e-14
Identities = 58/227 (25%), Positives = 103/227 (44%), Gaps = 10/227 (4%)
Frame = +1
Query: 142 FLDFLEEFQNSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVYPY 321
F +FL +S G + + ++ + R +LVV++ DL L+ + E
Sbjct: 199 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEA------- 251
Query: 322 LCRALKTFVKDRKEIPLA---------KDFYVAFQDLPTRHKIRELNSSRIGLLTRISGQ 474
L+ F + E+ LA +V LP ++R L + L R SG
Sbjct: 252 PAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 311
Query: 475 VVRTHPVHPELVSGTFLCLDCQTVIRDV-EQQFKYTQPNICRNPVCANRKRFLLDTNKSR 651
V V P+L + C C V+ + Q + +P C P C + F ++ ++
Sbjct: 312 VTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSC--PECQSAGPFEVNMEETI 369
Query: 652 FVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTG 792
+ ++Q++RIQE+ ++ G +PRS + IL A+ V+S + GD+ + TG
Sbjct: 370 YQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTG 416
>gi|33469968|ref|NP_005907.3| (NM_005916) minichromosome maintenance
protein 7 isoform 1; DNA replication licensing factor
MCM7; homolog of S. cerevisiae Cdc47 [Homo sapiens]
Length = 719
Score = 76.3 bits (186), Expect = 2e-14
Identities = 65/271 (23%), Positives = 108/271 (38%), Gaps = 43/271 (15%)
Frame = +1
Query: 124 EKCQKLFLDFLEEFQNSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEF 303
EK +K +F ++ + + KY L E+ L V D+ + + +L +I E
Sbjct: 11 EKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDPELVDSICENA 70
Query: 304 YRVYPYLCRALKTFVKDRKE-------------------------------------IPL 372
R A++ + KE L
Sbjct: 71 RRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGMVRSPQNQYPAEL 130
Query: 373 AKDFYVAFQDLPTRHK---IRELNSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQT 543
+ F + FQ P+ +K IRE+ + +G L + G V R V P++V T+ C C
Sbjct: 131 MRRFELYFQG-PSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGA 189
Query: 544 VIRDVEQQFKYTQPNICRNPVCANRK---RFLLDTNKSRFVDFQKVRIQETQAELPRGSI 714
Q + +C + C + R L T SRF+ FQ++++QE ++P G+I
Sbjct: 190 ETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNI 249
Query: 715 PRSLEVILRAEAVESAQAGDKCDFTGTLIVV 807
PRS+ V++ E AQ GD TG + +
Sbjct: 250 PRSITVLVEGENTRIAQPGDHVSVTGIFLPI 280
>gi|33469917|ref|NP_877423.1| (NM_182746) minichromosome maintenance
protein 4; homolog of S. pombe cell devision cycle 21;
DNA replication licensing factor MCM4 [Homo sapiens]
Length = 863
Score = 71.6 bits (174), Expect = 5e-13
Identities = 68/268 (25%), Positives = 113/268 (41%), Gaps = 13/268 (4%)
Frame = +1
Query: 46 SAAMDLAAAAEPSAGSQHLEVRDEVAEKCQKLFLDFLEEF--------QNSDGEIK---Y 192
+AA D+ A+ + + D C++ F FL+ F +N +I Y
Sbjct: 134 AAAEDIVASEQSLGQKLVIWGTDVNVAACKENFQRFLQRFIDPLAKEEENVGIDITEPLY 193
Query: 193 LQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDR-KEIP 369
+Q E+ L V+ ++ F++ L + V P A+ DR +
Sbjct: 194 MQRLGEINVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVNEIFFDRYPDSI 253
Query: 370 LAKDFYVA-FQDLPTRHKIRELNSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTV 546
L V F L T++ +R LN I L ISG V+RT + PE+ F C C
Sbjct: 254 LEHQIQVRPFNALKTKN-MRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHT 312
Query: 547 IRDVEQQFKYTQPNICRNPVCANRKRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSL 726
R + + +P++C C L N+S F D Q +++QE+ ++P G P ++
Sbjct: 313 TRVEMDRGRIAEPSVCGR--CHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTV 370
Query: 727 EVILRAEAVESAQAGDKCDFTGTLIVVP 810
+ + V+ Q GD+ + TG VP
Sbjct: 371 ILFAHNDLVDKVQPGDRVNVTGIYRAVP 398
>gi|33469919|ref|NP_005905.2| (NM_005914) minichromosome maintenance
protein 4; homolog of S. pombe cell devision cycle 21;
DNA replication licensing factor MCM4 [Homo sapiens]
Length = 863
Score = 71.6 bits (174), Expect = 5e-13
Identities = 68/268 (25%), Positives = 113/268 (41%), Gaps = 13/268 (4%)
Frame = +1
Query: 46 SAAMDLAAAAEPSAGSQHLEVRDEVAEKCQKLFLDFLEEF--------QNSDGEIK---Y 192
+AA D+ A+ + + D C++ F FL+ F +N +I Y
Sbjct: 134 AAAEDIVASEQSLGQKLVIWGTDVNVAACKENFQRFLQRFIDPLAKEEENVGIDITEPLY 193
Query: 193 LQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDR-KEIP 369
+Q E+ L V+ ++ F++ L + V P A+ DR +
Sbjct: 194 MQRLGEINVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVNEIFFDRYPDSI 253
Query: 370 LAKDFYVA-FQDLPTRHKIRELNSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTV 546
L V F L T++ +R LN I L ISG V+RT + PE+ F C C
Sbjct: 254 LEHQIQVRPFNALKTKN-MRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHT 312
Query: 547 IRDVEQQFKYTQPNICRNPVCANRKRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSL 726
R + + +P++C C L N+S F D Q +++QE+ ++P G P ++
Sbjct: 313 TRVEMDRGRIAEPSVCGR--CHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTV 370
Query: 727 EVILRAEAVESAQAGDKCDFTGTLIVVP 810
+ + V+ Q GD+ + TG VP
Sbjct: 371 ILFAHNDLVDKVQPGDRVNVTGIYRAVP 398
>gi|6631095|ref|NP_002379.2| (NM_002388) minichromosome maintenance
protein 3; DNA polymerase alpha holoenzyme-associated
protein P1; DNA replication factor MCM3; cervical cancer
proto-oncogene 5; hRlf beta subunit; replication
licensing factor, beta subunit [Homo sapiens]
Length = 808
Score = 64.3 bits (155), Expect = 9e-11
Identities = 61/243 (25%), Positives = 105/243 (43%), Gaps = 10/243 (4%)
Frame = +1
Query: 112 DEVAEKCQKLFLDFLEEFQNSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTI 291
D + Q+ +LDFL++ ++ Y ELI + L+V+ DL + N++ + +
Sbjct: 9 DVELREAQRDYLDFLDDEEDQG---IYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRL 65
Query: 292 QEEFYRVYPYLCRALKTFVK--DRKEIPLAKDFYVAFQ-DLPTRH-KIRELNSSRIGLLT 459
+ RALK FV D ++FYV + ++H R L S + +
Sbjct: 66 LNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVV 125
Query: 460 RISGQVVRTHPVHPELVSGTFLCLDCQTVIR----DVEQQFKYTQPNICRNPVCANRKRF 627
+ G V + V P++V C + I D+ + ++ N
Sbjct: 126 CVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNP-- 183
Query: 628 LLDTNK--SRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLI 801
L+T S + D Q + IQE + P G +PRS++VIL + V+ A+ GD+ GT
Sbjct: 184 -LETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYR 242
Query: 802 VVP 810
+P
Sbjct: 243 CLP 245
>gi|23397546|ref|NP_694987.1| (NM_153255) minichromosome maintenance
protein domain containing 1 [Homo sapiens]
Length = 391
Score = 63.2 bits (152), Expect = 2e-10
Identities = 55/244 (22%), Positives = 114/244 (46%), Gaps = 22/244 (9%)
Frame = +1
Query: 136 KLFLDFLEEFQNSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVY 315
++F ++ E+ +D L + +E +VV+ + L + N ++ E++ ++
Sbjct: 11 QVFESYVSEYHKND----ILLILKERDEDAHYPVVVNAMTLFETNMEIG-----EYFNMF 61
Query: 316 PY---------LCRALKTFVKDRKE---IPLAKDFYVAFQDLPTRHK-IREL--NSSRIG 450
P L R+ T ++ + + + ++ + LP + +RE + +G
Sbjct: 62 PSEVLTIFDSALRRSALTILQSLSQPEAVSMKQNLHARISGLPVCPELVREHIPKTKDVG 121
Query: 451 LLTRISGQVVRTHPVHPELVSGTFLCLDCQTVI---RDVEQQFKYTQPNICRNPVCANRK 621
++G V+RT V ++C C+ V D EQ + + +P+ C + +
Sbjct: 122 HFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFVIKADFEQYYTFCRPSSCPSLESCDSS 181
Query: 622 RFL----LDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFT 789
+F L ++ +R D+Q+++IQE L GSIPRS++VIL + V+S ++GD
Sbjct: 182 KFTCLSGLSSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIY 241
Query: 790 GTLI 801
G ++
Sbjct: 242 GIVM 245
>gi|33469922|ref|NP_877577.1| (NM_182776) minichromosome maintenance
protein 7 isoform 2; DNA replication licensing factor
MCM7; homolog of S. cerevisiae Cdc47 [Homo sapiens]
Length = 543
Score = 55.8 bits (133), Expect = 3e-08
Identities = 31/104 (29%), Positives = 50/104 (47%), Gaps = 3/104 (2%)
Frame = +1
Query: 505 LVSGTFLCLDCQTVIRDVEQQFKYTQPNICRNPVCANRK---RFLLDTNKSRFVDFQKVR 675
+V T+ C C Q + +C + C + R L T SRF+ FQ+++
Sbjct: 1 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMK 60
Query: 676 IQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVV 807
+QE ++P G+IPRS+ V++ E AQ GD TG + +
Sbjct: 61 MQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPI 104
>gi|33469924|ref|NP_877954.1| (NM_182802) minichromosome maintenance
protein 8 isoform 2; DNA replication licensing factor
MCM8 [Homo sapiens]
Length = 824
Score = 55.1 bits (131), Expect = 5e-08
Identities = 38/132 (28%), Positives = 62/132 (46%), Gaps = 3/132 (2%)
Frame = +1
Query: 418 KIRELNSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICR 597
+++ + ++ G + G VVR + P FLC C + KY+ P C
Sbjct: 206 QLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCP 265
Query: 598 NPVCANRKRFLLDTNK-SRFVDFQKVRIQETQAELPR--GSIPRSLEVILRAEAVESAQA 768
PVC R L ++ + +D+Q ++IQE ++ R G IPR++E L + V+S
Sbjct: 266 VPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVP 325
Query: 769 GDKCDFTGTLIV 804
GD TG + V
Sbjct: 326 GDTVTITGIVKV 337
>gi|19923727|ref|NP_115874.3| (NM_032485) minichromosome maintenance
protein 8 isoform 1; DNA replication licensing factor
MCM8 [Homo sapiens]
Length = 840
Score = 55.1 bits (131), Expect = 5e-08
Identities = 38/132 (28%), Positives = 62/132 (46%), Gaps = 3/132 (2%)
Frame = +1
Query: 418 KIRELNSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICR 597
+++ + ++ G + G VVR + P FLC C + KY+ P C
Sbjct: 206 QLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCP 265
Query: 598 NPVCANRKRFLLDTNK-SRFVDFQKVRIQETQAELPR--GSIPRSLEVILRAEAVESAQA 768
PVC R L ++ + +D+Q ++IQE ++ R G IPR++E L + V+S
Sbjct: 266 VPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVP 325
Query: 769 GDKCDFTGTLIV 804
GD TG + V
Sbjct: 326 GDTVTITGIVKV 337
Database: RefSeq (Homo Sapiens/Amino Acid)
Posted date: Sep 13, 2003 12:13 AM
Number of letters in database: 10,428,096
Number of sequences in database: 19,804
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,860,855
Number of Sequences: 19804
Number of extensions: 500839
Number of successful extensions: 2036
Number of sequences better than 10.0: 61
Number of HSP's better than 10.0 without gapping: 1767
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2023
length of database: 10,428,096
effective HSP length: 99
effective length of database: 8,467,500
effective search space used: 1795110000
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeq (Mouse) database
Query= 20030826C-005494 (20030826C-005494) 20030826C-005494
(937 letters)
Database: RefSeq (Mus Musculus/Amino Acid)
16,274 sequences; 7,609,334 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|6678832|ref|NP_032593.1| (NM_008567) minichromosome maintenan... 529 e-151
Alignment gi|6678826|ref|NP_032590.1| (NM_008564) minichromosome maintenan... 77 9e-15
Alignment gi|10242373|ref|NP_032594.1| (NM_008568) minichromosome maintena... 76 2e-14
Alignment gi|33859484|ref|NP_032589.1| (NM_008563) minichromosome maintena... 64 6e-11
Alignment gi|31982197|ref|NP_032591.2| (NM_008565) minichromosome maintena... 63 1e-10
Alignment gi|31542008|ref|NP_079952.2| (NM_025676) RIKEN cDNA 5730432L01 [... 53 1e-07
Alignment gi|6678830|ref|NP_032592.1| (NM_008566) minichromosome maintenan... 44 9e-05
Alignment gi|16923944|ref|NP_473383.1| (NM_054042) tumor endothelial marke... 31 0.59
Alignment gi|23956210|ref|NP_081701.1| (NM_027425) RUN and FYVE domain-con... 31 0.59
Alignment gi|9256535|ref|NP_061365.1| (NM_018877) SET domain, bifurcated 1... 30 1.3
>gi|6678832|ref|NP_032593.1| (NM_008567) minichromosome maintenance
protein 6; mini chromosome maintenance deficient 6 (S.
cerevisiae) [Mus musculus]
Length = 821
Score = 529 bits (1363), Expect = e-151
Identities = 265/277 (95%), Positives = 268/277 (96%)
Frame = +1
Query: 55 MDLAAAAEPSAGSQHLEVRDEVAEKCQKLFLDFLEEFQNSDGEIKYLQLAEELIRPERNT 234
MDLAAAAEP AGSQH EVRDEVAEKCQKLFLDFLEEFQ SDGEIKYLQ AEELIRPERNT
Sbjct: 1 MDLAAAAEPGAGSQHPEVRDEVAEKCQKLFLDFLEEFQGSDGEIKYLQFAEELIRPERNT 60
Query: 235 LVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDFYVAFQDLPTR 414
LVVSF DLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIP AKDFYVAFQDLPTR
Sbjct: 61 LVVSFADLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIPFAKDFYVAFQDLPTR 120
Query: 415 HKIRELNSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNIC 594
HKIREL SSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVI+DVEQQFKYTQPNIC
Sbjct: 121 HKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIKDVEQQFKYTQPNIC 180
Query: 595 RNPVCANRKRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGD 774
RNPVCANRKRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGD
Sbjct: 181 RNPVCANRKRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGD 240
Query: 775 KCDFTGTLIVVPDVSKLSTPGARAETNSRVNGVDGYE 885
+CDFTG LIVVPDVSKLSTPGARAETNSRV+G DGYE
Sbjct: 241 RCDFTGALIVVPDVSKLSTPGARAETNSRVSGADGYE 277
>gi|6678826|ref|NP_032590.1| (NM_008564) minichromosome maintenance
deficient 2 mitotin; mini chromosome maintenance
deficient 2 (S. cerevisiae) [Mus musculus]
Length = 904
Score = 77.0 bits (188), Expect = 9e-15
Identities = 58/227 (25%), Positives = 103/227 (44%), Gaps = 10/227 (4%)
Frame = +1
Query: 142 FLDFLEEFQNSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVYPY 321
F +FL +S G + + ++ + R +LVV++ DL L+ + E
Sbjct: 199 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEA------- 251
Query: 322 LCRALKTFVKDRKEIPLA---------KDFYVAFQDLPTRHKIRELNSSRIGLLTRISGQ 474
L+ F + E+ LA +V LP ++R L + L R SG
Sbjct: 252 PAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 311
Query: 475 VVRTHPVHPELVSGTFLCLDCQTVIRDV-EQQFKYTQPNICRNPVCANRKRFLLDTNKSR 651
V V P+L + C C V+ + Q + +P C P C + F ++ ++
Sbjct: 312 VTSCTGVLPQLSMVKYNCSKCNFVLGPFCQSQNQEVKPGSC--PECQSAGPFEINMEETI 369
Query: 652 FVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTG 792
+ ++Q++RIQE+ ++ G +PRS + IL A+ V+S + GD+ + TG
Sbjct: 370 YQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTG 416
>gi|10242373|ref|NP_032594.1| (NM_008568) minichromosome maintenance
protein 7; mini chromosome maintenance deficient 7 (S.
cerevisiae) [Mus musculus]
Length = 719
Score = 75.9 bits (185), Expect = 2e-14
Identities = 44/132 (33%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Frame = +1
Query: 421 IRELNSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICRN 600
IRE+ + +G L + G V R V P +V T+ C C Q + +C +
Sbjct: 149 IREVRADSVGKLLTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 208
Query: 601 PVCANRK---RFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAG 771
C + R L T S+FV FQ+++IQE ++P G+IPRS+ V+L E AQ G
Sbjct: 209 QECQTNRSGGRLYLQTRGSKFVKFQEMKIQEHSDQVPVGNIPRSITVVLEGENTRIAQPG 268
Query: 772 DKCDFTGTLIVV 807
D TG + V
Sbjct: 269 DHVSVTGIFLPV 280
>gi|33859484|ref|NP_032589.1| (NM_008563) minichromosome maintenance
deficient 3; mini chromosome maintenance deficient (S.
cerevisiae) [Mus musculus]
Length = 812
Score = 64.3 bits (155), Expect = 6e-11
Identities = 62/252 (24%), Positives = 106/252 (41%), Gaps = 10/252 (3%)
Frame = +1
Query: 112 DEVAEKCQKLFLDFLEEFQNSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTI 291
D + Q+ +LDFL++ ++ Y ELI + L+VS DL + N++ + +
Sbjct: 9 DVELREAQRDYLDFLDDEEDQG---IYQNKVRELISDNQYRLIVSVNDLRRKNEKRANRL 65
Query: 292 QEEFYRVYPYLCRALKTFVK--DRKEIPLAKDFYVAFQ-DLPTRH-KIRELNSSRIGLLT 459
+ RALK FV D ++FY+ + ++H R L S + +
Sbjct: 66 LNNAFEELVAFQRALKDFVASIDATYAKQYEEFYIGLEGSFGSKHVSPRTLTSCFLSCVV 125
Query: 460 RISGQVVRTHPVHPELVSGTFLCLDCQTVIR----DVEQQFKYTQPNICRNPVCANRKRF 627
+ G V + V P++V C + I D+ + ++ N
Sbjct: 126 CVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNP-- 183
Query: 628 LLDTNK--SRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLI 801
L+T S + D Q + IQE + P G +PRS++VIL + V+ + GD+ GT
Sbjct: 184 -LETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYR 242
Query: 802 VVPDVSKLSTPG 837
+P T G
Sbjct: 243 CLPGKKGCYTSG 254
>gi|31982197|ref|NP_032591.2| (NM_008565) minichromosome maintenance
protein 4; mini chromosome maintenance deficient 4
homolog (S. cerevisiae) [Mus musculus]
Length = 862
Score = 63.2 bits (152), Expect = 1e-10
Identities = 41/139 (29%), Positives = 64/139 (45%)
Frame = +1
Query: 394 FQDLPTRHKIRELNSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFK 573
F L T+ +R LN I L ISG V+RT + PE+ F C R + +
Sbjct: 262 FNALKTK-SMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVSAHTTRVEIDRGR 320
Query: 574 YTQPNICRNPVCANRKRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAV 753
+P C + C L N+S F D Q +++QE+ ++P G P ++ + + V
Sbjct: 321 IAEPCSCVH--CHTTHSMALIHNRSFFSDKQMIKLQESPEDMPAGQTPHTIVLFAHNDLV 378
Query: 754 ESAQAGDKCDFTGTLIVVP 810
+ Q GD+ + TG VP
Sbjct: 379 DKVQPGDRVNVTGIYRAVP 397
>gi|31542008|ref|NP_079952.2| (NM_025676) RIKEN cDNA 5730432L01 [Mus
musculus]
Length = 805
Score = 53.1 bits (126), Expect = 1e-07
Identities = 40/136 (29%), Positives = 62/136 (45%), Gaps = 3/136 (2%)
Frame = +1
Query: 406 PTRHKIRELNSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQP 585
P H ++ + ++ G I G VVR + P + F C C + KYT P
Sbjct: 168 PLTH-LKNIRATCYGKYISIRGTVVRVSNIKPLCTNMAFQCAACGEIQSFPLPDGKYTLP 226
Query: 586 NICRNPVCANRKRFLLDTNK-SRFVDFQKVRIQETQAELPR--GSIPRSLEVILRAEAVE 756
C P C R L ++ + +D+Q ++IQE ++ R G IPR++E L + V+
Sbjct: 227 TKCPVPACRGRSFAPLRSSPLTVTLDWQLIKIQELMSDAQREAGRIPRTIECELVHDLVD 286
Query: 757 SAQAGDKCDFTGTLIV 804
S GD TG + V
Sbjct: 287 SCVPGDTVTVTGIVKV 302
>gi|6678830|ref|NP_032592.1| (NM_008566) minichromosome maintenance
deficient 5, cell division cycle 46; mini chromosome
maintenance deficient 5 (S. cerevisiae); DNA replication
licensing factor [Mus musculus]
Length = 733
Score = 43.9 bits (102), Expect = 9e-05
Identities = 47/237 (19%), Positives = 91/237 (37%), Gaps = 17/237 (7%)
Frame = +1
Query: 133 QKLFLDFLEEFQNSDGEIKYLQLAEELIRPERNT----LVVSFVDLEQFNQQLSTTIQEE 300
Q+ F +FL +++ + + ++ N + V DL F+++L+ + ++
Sbjct: 32 QRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEELADHLHKQ 91
Query: 301 FYRVYPYLCRALKTFVKDRKEIP------LAKDFYVAFQDLPTRHKIRELNSSRIGLLTR 462
L A K V D P L +D V + + IR L S + L +
Sbjct: 92 PAEHLQLLEEAAKE-VADEVTRPRPAGDELLQDIQVMLKSDASPSSIRILKSDMMSHLVK 150
Query: 463 ISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFK--YTQPNICR-----NPVCANRK 621
I G ++ V + + C C + ++ P C P C
Sbjct: 151 IPGIIISASAVRAKATRISIQCRSCHNTLTNIAMPRPRGLCLPRKCNMDQAGRPKCPLDP 210
Query: 622 RFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTG 792
F++ +K + VDFQ +++QE +P G +PR +++ + G++ G
Sbjct: 211 YFIMP-DKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMG 266
>gi|16923944|ref|NP_473383.1| (NM_054042) tumor endothelial marker 1
precursor [Mus musculus]
Length = 765
Score = 31.2 bits (69), Expect = 0.59
Identities = 26/85 (30%), Positives = 32/85 (37%)
Frame = -1
Query: 259 PGPQNSQPMCFSQDELVPQLTAST*FLHRCSGIPPRNLGTISGTFRPPRRGLLSAGCRRS 80
P P +QP F L PQ P +IS T R L+ R
Sbjct: 614 PVPAANQPPAFPSSPLPPQR-------------PTNQTSSISPTHSYSRAPLVP---REG 657
Query: 79 VPLPPRGPWLPSAEEPPAPRSIAKS 5
VP P P LPS AP ++A+S
Sbjct: 658 VPSPKSVPQLPSVPSTAAPTALAES 682
>gi|23956210|ref|NP_081701.1| (NM_027425) RUN and FYVE
domain-containing 2; differentially expressed in normal
and neoplastic cells [Mus musculus]
Length = 606
Score = 31.2 bits (69), Expect = 0.59
Identities = 24/86 (27%), Positives = 44/86 (50%), Gaps = 4/86 (4%)
Frame = +1
Query: 190 YLQLAEELIRPERNTLVVSFVD----LEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDR 357
YL+ EE+ ERN + + +D +E+ N+QL++T+ RV K+ K
Sbjct: 183 YLKNEEEIGNKERNVQIAAILDQKNCVEELNRQLNSTVSSLHSRV----DSLEKSNTKLI 238
Query: 358 KEIPLAKDFYVAFQDLPTRHKIRELN 435
+E+ +AK+ + Q+ H++R N
Sbjct: 239 EELAIAKNNIIKLQE--ENHQLRSEN 262
>gi|9256535|ref|NP_061365.1| (NM_018877) SET domain, bifurcated 1
[Mus musculus]
Length = 1307
Score = 30.0 bits (66), Expect = 1.3
Identities = 14/39 (35%), Positives = 20/39 (50%)
Frame = -1
Query: 139 ISGTFRPPRRGLLSAGCRRSVPLPPRGPWLPSAEEPPAP 23
I+ T+R P + S + P+PP P P+ PPAP
Sbjct: 521 INQTYRSPLASVTSTPASAAPPVPPVPPGPPTPPGPPAP 559
Database: RefSeq (Mus Musculus/Amino Acid)
Posted date: Sep 13, 2003 12:13 AM
Number of letters in database: 7,609,334
Number of sequences in database: 16,274
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,425,010
Number of Sequences: 16274
Number of extensions: 356741
Number of successful extensions: 1449
Number of sequences better than 10.0: 44
Number of HSP's better than 10.0 without gapping: 1225
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1438
length of database: 7,609,334
effective HSP length: 97
effective length of database: 6,030,756
effective search space used: 1290581784
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)