Animal-Genome cDNA 20060611C-000407

BLASTX 2.2.10 [Oct-19-2004]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20060611C-000407
         (1422 letters)

Database: RefSeqBP 
           33,508 sequences; 16,112,626 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_776376.1| plasminogen [Bos taurus]                             789   0.0  
Alignment   gi|XP_592554.2| PREDICTED: similar to Hepatocyte growth factor-...   351   9e-97
Alignment   gi|NP_001026921.1| hepatocyte growth factor [Bos taurus]             318   5e-87
Alignment   gi|XP_874086.1| PREDICTED: hepatocyte growth factor [Bos taurus]     318   5e-87
Alignment   gi|NP_776571.2| plasminogen activator, tissue [Bos taurus]           242   5e-64
Alignment   gi|XP_584887.2| PREDICTED: similar to Serine protease hepsin (T...   200   3e-51
Alignment   gi|XP_886646.1| PREDICTED: similar to Serine protease hepsin (T...   200   3e-51
Alignment   gi|XP_618102.2| PREDICTED: similar to Transmembrane protease, s...   200   3e-51
Alignment   gi|NP_001014868.1| hyaluronan binding protein 2 [Bos taurus]         198   8e-51
Alignment   gi|XP_607216.2| PREDICTED: similar to protease, serine, 33 [Bos...   193   2e-49

>ref|NP_776376.1| plasminogen [Bos taurus]
          Length = 812

 Score =  789 bits (2038), Expect = 0.0
 Identities = 369/465 (79%), Positives = 397/465 (85%), Gaps = 1/465 (0%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
            YC IPSC SS  STE +D PVPPEQTPV QDCY GNG+SYRGTSSTTITGRKCQSW SMT
Sbjct: 353  YCTIPSCESSPLSTERMDVPVPPEQTPVPQDCYHGNGQSYRGTSSTTITGRKCQSWSSMT 412

Query: 182  PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFP 361
            PHRH KTP N+PNAGLTMNYCRNPDADKSPWCYTTDPRVRWE+CNLKKCSET +QV   P
Sbjct: 413  PHRHLKTPENYPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEFCNLKKCSETPEQV---P 469

Query: 362  AIVQVPSVEDLSE-DCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAG 538
            A  Q P VE+  E DCM G GK YRGK+ATTVAGVPCQEWAAQEPH+HSIFTPETNP++G
Sbjct: 470  AAPQAPGVENPPEADCMIGTGKSYRGKKATTVAGVPCQEWAAQEPHQHSIFTPETNPQSG 529

Query: 539  LEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETSSFDCGKPKMEPKKCPARVVGGC 718
            LE+NYCRNPDGD NGPWCYT NP+K FDYCDVPQCE SSFDCGKPK+EPKKC  R+VGGC
Sbjct: 530  LERNYCRNPDGDVNGPWCYTMNPRKPFDYCDVPQCE-SSFDCGKPKVEPKKCSGRIVGGC 588

Query: 719  VSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHL 898
            VS PHSWPWQ+SLRR    HFCGGTLISP+WVLTA HCL+   + S YKVILGAH E   
Sbjct: 589  VSKPHSWPWQVSLRRS-SRHFCGGTLISPKWVLTAAHCLDNILALSFYKVILGAHNEKVR 647

Query: 899  GEGVQEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLPTPNYVVADRTACYITGWG 1078
             + VQEI VS+LF+EPS ADIALLKLS PA+IT +VIPACLP PNY+VA RT CYITGWG
Sbjct: 648  EQSVQEIPVSRLFREPSQADIALLKLSRPAIITKEVIPACLPPPNYMVAARTECYITGWG 707

Query: 1079 ETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLV 1258
            ET+GT+G GLLKEA LPVIENKVCNR EYL G+V P ELCAGHL GG DSCQGDSGGPLV
Sbjct: 708  ETQGTFGEGLLKEAHLPVIENKVCNRNEYLDGRVKPTELCAGHLIGGTDSCQGDSGGPLV 767

Query: 1259 CFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIMRRN 1393
            CFEKDKYILQGVTSWGLGCA PNKPGVYVRV  +V WIEE MRRN
Sbjct: 768  CFEKDKYILQGVTSWGLGCARPNKPGVYVRVSPYVPWIEETMRRN 812



 Score =  207 bits (528), Expect = 1e-53
 Identities = 102/258 (39%), Positives = 138/258 (53%)
 Frame = +2

Query: 2   YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
           +C IP C +            PP   P  Q C +G G++Y GT + T +G  CQ W   T
Sbjct: 263 FCDIPRCTTP-----------PPSSGPKYQ-CLKGTGKNYGGTVAVTESGHTCQRWSEQT 310

Query: 182 PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFP 361
           PH+H +TP NFP   L  NYCRNP+ +K+PWCYTT+  VRWEYC +  C E+    T   
Sbjct: 311 PHKHNRTPENFPCKNLEENYCRNPNGEKAPWCYTTNSEVRWEYCTIPSC-ESSPLSTERM 369

Query: 362 AIVQVPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGL 541
            +   P    + +DC  GNG+ YRG  +TT+ G  CQ W++  PHRH + TPE  P AGL
Sbjct: 370 DVPVPPEQTPVPQDCYHGNGQSYRGTSSTTITGRKCQSWSSMTPHRH-LKTPENYPNAGL 428

Query: 542 EKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETSSFDCGKPKMEPKKCPARVVGGCV 721
             NYCRNPD  D  PWCYTT+P+  +++C++ +C  +          P++ PA      V
Sbjct: 429 TMNYCRNPDA-DKSPWCYTTDPRVRWEFCNLKKCSET----------PEQVPAAPQAPGV 477

Query: 722 SIPHSWPWQISLRRRYGG 775
             P      I   + Y G
Sbjct: 478 ENPPEADCMIGTGKSYRG 495



 Score =  189 bits (481), Expect = 4e-48
 Identities = 85/192 (44%), Positives = 114/192 (59%), Gaps = 1/192 (0%)
 Frame = +2

Query: 80  PVAQD-CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPD 256
           P  +D C   +GE+Y G  + T++GR CQ+W S +PH H   P  FPN  L MNYCRNPD
Sbjct: 186 PECEDKCMHCSGENYEGKIAKTMSGRDCQAWDSQSPHAHGYIPSKFPNKNLKMNYCRNPD 245

Query: 257 ADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRG 436
            +  PWC+TTDP+ RWE+C++ +C+               P        C+ G GK Y G
Sbjct: 246 GEPRPWCFTTDPQKRWEFCDIPRCTTP-------------PPSSGPKYQCLKGTGKNYGG 292

Query: 437 KRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKL 616
             A T +G  CQ W+ Q PH+H+  TPE  P   LE+NYCRNP+G +  PWCYTTN +  
Sbjct: 293 TVAVTESGHTCQRWSEQTPHKHN-RTPENFPCKNLEENYCRNPNG-EKAPWCYTTNSEVR 350

Query: 617 FDYCDVPQCETS 652
           ++YC +P CE+S
Sbjct: 351 WEYCTIPSCESS 362



 Score =  186 bits (471), Expect = 5e-47
 Identities = 89/216 (41%), Positives = 126/216 (58%), Gaps = 1/216 (0%)
 Frame = +2

Query: 92  DCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKS- 268
           +C  GNG++YRGT++ T +G  CQ W + +PH  + +P  FP AGL  NYCRNPD D++ 
Sbjct: 109 ECKTGNGQTYRGTTAETKSGVTCQKWSATSPHVPKFSPEKFPLAGLEENYCRNPDNDENG 168

Query: 269 PWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRGKRAT 448
           PWCYTTDP  R++YC++ +C                       + CM  +G+ Y GK A 
Sbjct: 169 PWCYTTDPDKRYDYCDIPEC----------------------EDKCMHCSGENYEGKIAK 206

Query: 449 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 628
           T++G  CQ W +Q PH H  + P   P   L+ NYCRNPDG+   PWC+TT+PQK +++C
Sbjct: 207 TMSGRDCQAWDSQSPHAHG-YIPSKFPNKNLKMNYCRNPDGEPR-PWCFTTDPQKRWEFC 264

Query: 629 DVPQCETSSFDCGKPKMEPKKCPARVVGGCVSIPHS 736
           D+P+C T     G PK +  K   +  GG V++  S
Sbjct: 265 DIPRCTTPPPSSG-PKYQCLKGTGKNYGGTVAVTES 299


>ref|XP_592554.2| PREDICTED: similar to Hepatocyte growth factor-like protein precursor
            (Macrophage stimulatory protein) (MSP) (Macrophage
            stimulating protein) [Bos taurus]
          Length = 711

 Score =  351 bits (900), Expect = 9e-97
 Identities = 187/481 (38%), Positives = 259/481 (53%), Gaps = 19/481 (3%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
            +C +P CGS             P Q     +C+RG GE YRGT +TT  G  CQ W +  
Sbjct: 262  FCDLPRCGSEAQ----------PSQEATTLNCFRGKGEGYRGTVNTTAAGVPCQRWDAQL 311

Query: 182  PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYC-NLKKCSETEQQVTNF 358
            PH+H   P  +    L  N+CRNPD  ++PWC+T+ P +R  +C  +++C++  +     
Sbjct: 312  PHQHRFAPEKYACKDLRENFCRNPDGSEAPWCFTSRPGMRMAFCYQIRRCTDDVR----- 366

Query: 359  PAIVQVPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAG 538
                         EDC  G G+ YRG  + T  G+ CQ W+A+ PH+   F   + P   
Sbjct: 367  ------------PEDCYHGAGELYRGSVSKTRKGIRCQNWSAETPHKPQ-FKHTSAPHTP 413

Query: 539  LEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETSS------------FD-CGK--P 673
            LE+N+CRNPDGD +GPWCYTT+P   FDYC + +C+               FD CGK   
Sbjct: 414  LEENFCRNPDGDSHGPWCYTTDPGTPFDYCALRRCDDDQQPSILETAHQVLFDKCGKRVT 473

Query: 674  KMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEK-SSS 850
            +++P     RVVGG    P + PW +SLR R G HFCGG+L+  +WVLTA+ C      S
Sbjct: 474  RVDPLHSKLRVVGG---QPGNSPWTVSLRNRQGQHFCGGSLVKEQWVLTARQCFSSCHMS 530

Query: 851  PSSYKVILGA-HEEHHLGE-GVQEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLP 1024
               Y+V LG   ++   GE  +Q I ++K+   PSG+ + LLKL  P ++  +V   CLP
Sbjct: 531  LVGYEVWLGTLFQDPQPGEPDLQHIPMAKMVCGPSGSQLVLLKLERPVILNQRVALICLP 590

Query: 1025 TPNYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAG 1204
               YVV   T C I GWGETKGT    +L  A L VI N+ CN      G+V  +E+C  
Sbjct: 591  PERYVVPPGTRCEIAGWGETKGTGDDTVLNIALLSVISNQECNVKH--RGRVRESEMCTA 648

Query: 1205 HLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIM 1384
             L   + +C+GD GGPL CF  D ++LQG+      CA P  P +++RV  FV WI ++M
Sbjct: 649  GLLAPVGACEGDYGGPLACFTHDCWVLQGIIIPNRVCARPRWPAIFMRVSVFVDWIHKVM 708

Query: 1385 R 1387
            R
Sbjct: 709  R 709



 Score =  168 bits (426), Expect = 8e-42
 Identities = 80/178 (44%), Positives = 101/178 (56%)
 Frame = +2

Query: 95  CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPW 274
           C   NGE YRG+  +T +GR+CQ W    PH H   PG F +  L  NYCRNPD  + PW
Sbjct: 191 CLWCNGEDYRGSVDSTESGRECQRWDLQHPHPHPFEPGKFLDKNLDDNYCRNPDGSERPW 250

Query: 275 CYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRGKRATTV 454
           CYTTDP++  E+C+L +C    Q           PS E  + +C  G G+ YRG   TT 
Sbjct: 251 CYTTDPQMEREFCDLPRCGSEAQ-----------PSQEATTLNCFRGKGEGYRGTVNTTA 299

Query: 455 AGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 628
           AGVPCQ W AQ PH+H  F PE      L +N+CRNPDG +  PWC+T+ P     +C
Sbjct: 300 AGVPCQRWDAQLPHQHR-FAPEKYACKDLRENFCRNPDGSE-APWCFTSRPGMRMAFC 355



 Score =  151 bits (381), Expect = 1e-36
 Identities = 81/205 (39%), Positives = 105/205 (51%), Gaps = 9/205 (4%)
 Frame = +2

Query: 95  CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKS-P 271
           C   NG  YRGT + T+ G  CQ W    P+ H+ TP      GL  N+CRNPD D   P
Sbjct: 110 CIVDNGVEYRGTVAITVGGLPCQRWSHRFPNDHKFTPTL--RNGLEENFCRNPDRDPGGP 167

Query: 272 WCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRGKRATT 451
           WCYTTDP VR++ C +K C E                       C++ NG+ YRG   +T
Sbjct: 168 WCYTTDPAVRFQSCGIKSCREA---------------------TCLWCNGEDYRGSVDST 206

Query: 452 VAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCD 631
            +G  CQ W  Q PH H  F P       L+ NYCRNPDG +  PWCYTT+PQ   ++CD
Sbjct: 207 ESGRECQRWDLQHPHPHP-FEPGKFLDKNLDDNYCRNPDGSER-PWCYTTDPQMEREFCD 264

Query: 632 VPQC--------ETSSFDCGKPKME 682
           +P+C        E ++ +C + K E
Sbjct: 265 LPRCGSEAQPSQEATTLNCFRGKGE 289


>ref|NP_001026921.1| hepatocyte growth factor [Bos taurus]
          Length = 730

 Score =  318 bits (816), Expect = 5e-87
 Identities = 182/480 (37%), Positives = 253/480 (52%), Gaps = 19/480 (3%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
            YC I  C  ST +    D  +P + T    +C +G GE YRGT +T   G  CQ W S  
Sbjct: 282  YCAIKMCAHSTMN----DTDLPMQTT----ECIQGQGEGYRGTINTIWNGIPCQRWDSQY 333

Query: 182  PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFP 361
            PH+H+ TP NF    L  NYCRNPD  +SPWC+TTDP +R  YC+               
Sbjct: 334  PHQHDITPENFKCKDLRENYCRNPDGAESPWCFTTDPNIRVGYCS--------------- 378

Query: 362  AIVQVPSVEDLS-EDCMFGNGKRYRGKRATTVAGVPCQEWAA--QEPHRHSIFTPETNPR 532
               Q+P  +  S +DC  GNGK Y G  + T +G+ C  W    ++ HRH  + P+    
Sbjct: 379  ---QIPKCDVSSGQDCYRGNGKNYMGSLSKTRSGLTCSMWDKNMEDLHRHIFWEPDATK- 434

Query: 533  AGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETSS-----------FDCGKPKM 679
              L KNYCRNPD D +GPWCYT NP   +DYC + +CE  +             C K K 
Sbjct: 435  --LNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTKQ 492

Query: 680  EPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCL-EKSSSPS 856
                   RVV G +    +  W +SL+ R   H CGG+LI   W+LTA+ C   ++    
Sbjct: 493  ------LRVVNG-IPTRTNVGWMVSLKYR-NKHICGGSLIKESWILTARQCFPSRNKDLK 544

Query: 857  SYKVILGAHEEHHLGEGV--QEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLPTP 1030
             Y+  LG H+ H  G+    Q ++V++L   P G+D+ LLKL+ PA++ D V    LP  
Sbjct: 545  DYEAWLGIHDVHGRGDEKRKQVLNVTQLVYGPEGSDLVLLKLARPAILDDFVSTIDLPNY 604

Query: 1031 NYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPN--ELCAG 1204
               + ++T C + GWG T      GLL+ A L ++ N+ C++Y    GKV+ N  E+CAG
Sbjct: 605  GCTIPEKTTCSVYGWGYTGLINSDGLLRVAHLYIMGNEKCSQYHQ--GKVTLNESEICAG 662

Query: 1205 HLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIM 1384
                    C+GD GGPLVC +    ++ GV   G GCA+PN+PG++VRV  +  WI +I+
Sbjct: 663  AENIVSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 722



 Score =  183 bits (464), Expect = 3e-46
 Identities = 90/215 (41%), Positives = 115/215 (53%), Gaps = 1/215 (0%)
 Frame = +2

Query: 14  PSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRH 193
           P C +S     Y    +P         C   NGESYRG    T TG+ CQ W   TPHRH
Sbjct: 187 PWCFTSNPEVRYEVCDIPQCSEVECMTC---NGESYRGPMDHTETGKICQRWDHQTPHRH 243

Query: 194 EKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQ 373
           +  P  +P+ G   NYCRNPD    PWCYT DP   WEYC +K C+ +    T+ P    
Sbjct: 244 KFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMCAHSTMNDTDLPM--- 300

Query: 374 VPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNY 553
                  + +C+ G G+ YRG   T   G+PCQ W +Q PH+H I TPE      L +NY
Sbjct: 301 ------QTTECIQGQGEGYRGTINTIWNGIPCQRWDSQYPHQHDI-TPENFKCKDLRENY 353

Query: 554 CRNPDGDDNGPWCYTTNPQKLFDYC-DVPQCETSS 655
           CRNPDG ++ PWC+TT+P     YC  +P+C+ SS
Sbjct: 354 CRNPDGAES-PWCFTTDPNIRVGYCSQIPKCDVSS 387



 Score =  166 bits (420), Expect = 4e-41
 Identities = 83/209 (39%), Positives = 108/209 (51%), Gaps = 1/209 (0%)
 Frame = +2

Query: 71  EQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRN 250
           E     ++C  G G SY+GT S T +G KCQ W SM PH H   P ++    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 251 PDADK-SPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKR 427
           P  ++  PWC+T++P VR+E C++ +CSE E                     CM  NG+ 
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE---------------------CMTCNGES 218

Query: 428 YRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNP 607
           YRG    T  G  CQ W  Q PHRH  F PE  P  G + NYCRNPDG    PWCYT +P
Sbjct: 219 YRGPMDHTETGKICQRWDHQTPHRHK-FLPERYPDKGFDDNYCRNPDGKPR-PWCYTLDP 276

Query: 608 QKLFDYCDVPQCETSSFDCGKPKMEPKKC 694
              ++YC +  C  S+ +     M+  +C
Sbjct: 277 DTPWEYCAIKMCAHSTMNDTDLPMQTTEC 305


>ref|XP_874086.1| PREDICTED: hepatocyte growth factor [Bos taurus]
          Length = 697

 Score =  318 bits (816), Expect = 5e-87
 Identities = 182/480 (37%), Positives = 253/480 (52%), Gaps = 19/480 (3%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
            YC I  C  ST +    D  +P + T    +C +G GE YRGT +T   G  CQ W S  
Sbjct: 249  YCAIKMCAHSTMN----DTDLPMQTT----ECIQGQGEGYRGTINTIWNGIPCQRWDSQY 300

Query: 182  PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFP 361
            PH+H+ TP NF    L  NYCRNPD  +SPWC+TTDP +R  YC+               
Sbjct: 301  PHQHDITPENFKCKDLRENYCRNPDGAESPWCFTTDPNIRVGYCS--------------- 345

Query: 362  AIVQVPSVEDLS-EDCMFGNGKRYRGKRATTVAGVPCQEWAA--QEPHRHSIFTPETNPR 532
               Q+P  +  S +DC  GNGK Y G  + T +G+ C  W    ++ HRH  + P+    
Sbjct: 346  ---QIPKCDVSSGQDCYRGNGKNYMGSLSKTRSGLTCSMWDKNMEDLHRHIFWEPDATK- 401

Query: 533  AGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETSS-----------FDCGKPKM 679
              L KNYCRNPD D +GPWCYT NP   +DYC + +CE  +             C K K 
Sbjct: 402  --LNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTKQ 459

Query: 680  EPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCL-EKSSSPS 856
                   RVV G +    +  W +SL+ R   H CGG+LI   W+LTA+ C   ++    
Sbjct: 460  ------LRVVNG-IPTRTNVGWMVSLKYR-NKHICGGSLIKESWILTARQCFPSRNKDLK 511

Query: 857  SYKVILGAHEEHHLGEGV--QEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLPTP 1030
             Y+  LG H+ H  G+    Q ++V++L   P G+D+ LLKL+ PA++ D V    LP  
Sbjct: 512  DYEAWLGIHDVHGRGDEKRKQVLNVTQLVYGPEGSDLVLLKLARPAILDDFVSTIDLPNY 571

Query: 1031 NYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPN--ELCAG 1204
               + ++T C + GWG T      GLL+ A L ++ N+ C++Y    GKV+ N  E+CAG
Sbjct: 572  GCTIPEKTTCSVYGWGYTGLINSDGLLRVAHLYIMGNEKCSQYHQ--GKVTLNESEICAG 629

Query: 1205 HLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIM 1384
                    C+GD GGPLVC +    ++ GV   G GCA+PN+PG++VRV  +  WI +I+
Sbjct: 630  AENIVSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 689



 Score =  183 bits (464), Expect = 3e-46
 Identities = 90/215 (41%), Positives = 115/215 (53%), Gaps = 1/215 (0%)
 Frame = +2

Query: 14  PSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRH 193
           P C +S     Y    +P         C   NGESYRG    T TG+ CQ W   TPHRH
Sbjct: 154 PWCFTSNPEVRYEVCDIPQCSEVECMTC---NGESYRGPMDHTETGKICQRWDHQTPHRH 210

Query: 194 EKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQ 373
           +  P  +P+ G   NYCRNPD    PWCYT DP   WEYC +K C+ +    T+ P    
Sbjct: 211 KFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMCAHSTMNDTDLPM--- 267

Query: 374 VPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNY 553
                  + +C+ G G+ YRG   T   G+PCQ W +Q PH+H I TPE      L +NY
Sbjct: 268 ------QTTECIQGQGEGYRGTINTIWNGIPCQRWDSQYPHQHDI-TPENFKCKDLRENY 320

Query: 554 CRNPDGDDNGPWCYTTNPQKLFDYC-DVPQCETSS 655
           CRNPDG ++ PWC+TT+P     YC  +P+C+ SS
Sbjct: 321 CRNPDGAES-PWCFTTDPNIRVGYCSQIPKCDVSS 354



 Score =  166 bits (420), Expect = 4e-41
 Identities = 83/209 (39%), Positives = 108/209 (51%), Gaps = 1/209 (0%)
 Frame = +2

Query: 71  EQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRN 250
           E     ++C  G G SY+GT S T +G KCQ W SM PH H   P ++    L  NYCRN
Sbjct: 87  ENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRN 146

Query: 251 PDADK-SPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKR 427
           P  ++  PWC+T++P VR+E C++ +CSE E                     CM  NG+ 
Sbjct: 147 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE---------------------CMTCNGES 185

Query: 428 YRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNP 607
           YRG    T  G  CQ W  Q PHRH  F PE  P  G + NYCRNPDG    PWCYT +P
Sbjct: 186 YRGPMDHTETGKICQRWDHQTPHRHK-FLPERYPDKGFDDNYCRNPDGKPR-PWCYTLDP 243

Query: 608 QKLFDYCDVPQCETSSFDCGKPKMEPKKC 694
              ++YC +  C  S+ +     M+  +C
Sbjct: 244 DTPWEYCAIKMCAHSTMNDTDLPMQTTEC 272


>ref|NP_776571.2| plasminogen activator, tissue [Bos taurus]
          Length = 566

 Score =  242 bits (618), Expect = 5e-64
 Identities = 166/466 (35%), Positives = 227/466 (48%), Gaps = 35/466 (7%)
 Frame = +2

Query: 95   CYRGNGESYRGTSSTTITGRKCQSW----VSMTPHRHEKTPGNFPNA---GL-TMNYCRN 250
            CY+  G +YRGT ST  +G +C +W    ++M P+      G  PNA   GL   NYCRN
Sbjct: 128  CYKDQGVAYRGTWSTAESGAECANWNSSGLAMKPYS-----GRRPNAIRLGLGNHNYCRN 182

Query: 251  PDADKSPWCYTTDP-RVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKR 427
            PD D  PWCY     +   E+C+   C++  ++                  DC  GNG  
Sbjct: 183  PDQDSKPWCYVFKAGKYISEFCSTPACAKVAEE----------------DGDCYTGNGLA 226

Query: 428  YRGKRATTVAGVPCQEWAAQEPHRHSIFTPETN-PRAGLEK-NYCRNPDGDDNGPWCYTT 601
            YRG R+ T +G  C  W +           ++N P  GL K N+CRNPDGD   PWC+  
Sbjct: 227  YRGTRSHTKSGASCLPWNSVFLTSKIYTAWKSNAPALGLGKHNHCRNPDGDAQ-PWCHVW 285

Query: 602  NPQKL-FDYCDVPQCETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISL----RRR 766
              ++L ++YCDVPQC T    CG  +   K+   R+ GG  +   S PWQ ++    RR 
Sbjct: 286  KDRQLTWEYCDVPQCVT----CGLRQY--KRPQFRIKGGLFADITSHPWQAAIFVKNRRS 339

Query: 767  YGGHF-CGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLF-- 937
             G  F CGG LIS  WVL+A HC ++   P   KV LG       GE  Q  +V K    
Sbjct: 340  PGERFLCGGILISSCWVLSAAHCFQERYPPLHLKVFLGRTYRLVPGEEEQTFEVEKYIIH 399

Query: 938  ----KEPSGADIALLKLSSPAVITDK----VIPACLPTPNYVVADRTACYITGWG--ETK 1087
                 +    DIALL L S ++   +    V   CLP  +  + D T C ++G+G  E+ 
Sbjct: 400  KEFDDDTYDNDIALLHLKSDSLTCARESASVRTICLPDASLQLPDWTECELSGYGKHESS 459

Query: 1088 GTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAGHLAGG------IDSCQGDSGG 1249
              + +  LKEA + +  +  C         V+ N LCAG    G       D+CQGDSGG
Sbjct: 460  SPFFSERLKEAHVRLYPSSRCTSQHLFNRTVTNNMLCAGDTRSGGDHTNLHDACQGDSGG 519

Query: 1250 PLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIMR 1387
            PLVC + +   L G+ SWGLGC   + PGVY +V  ++ WI +  R
Sbjct: 520  PLVCMKDNHMTLVGIISWGLGCGRKDVPGVYTKVTNYLDWIRDNTR 565



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 39/100 (39%), Positives = 53/100 (53%), Gaps = 4/100 (4%)
 Frame = +2

Query: 41  TEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSW--VSMTPHRHEKTPGNF 214
           +E+   P   +      DCY GNG +YRGT S T +G  C  W  V +T   +     N 
Sbjct: 201 SEFCSTPACAKVAEEDGDCYTGNGLAYRGTRSHTKSGASCLPWNSVFLTSKIYTAWKSNA 260

Query: 215 PNAGL-TMNYCRNPDADKSPWCYT-TDPRVRWEYCNLKKC 328
           P  GL   N+CRNPD D  PWC+   D ++ WEYC++ +C
Sbjct: 261 PALGLGKHNHCRNPDGDAQPWCHVWKDRQLTWEYCDVPQC 300


>ref|XP_584887.2| PREDICTED: similar to Serine protease hepsin (Transmembrane protease,
            serine 1) isoform 2 [Bos taurus]
          Length = 417

 Score =  200 bits (508), Expect = 3e-51
 Identities = 124/332 (37%), Positives = 174/332 (52%), Gaps = 20/332 (6%)
 Frame = +2

Query: 452  VAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCD 631
            VAG+ C+E         S     T    G    +C      D G   +     ++   CD
Sbjct: 85   VAGLSCEEMGFLRALDFSELDVRTAGANGTSGFFCV-----DEGRLPHARRLLEVLSVCD 139

Query: 632  VPQ---CETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLIS 802
             P+     TS  DCG  K+       R+VGG  +    WPWQ+SLR   G H CGG+++S
Sbjct: 140  CPRGRFLATSCQDCGHRKLPVD----RIVGGQDTSLGRWPWQVSLRYD-GAHLCGGSVLS 194

Query: 803  PEWVLTAKHCL-EKSSSPSSYKVILGAHEE---HHLGEGVQEIDVSK---LFKEPSGA-- 955
             +WVLTA HC  E++   S ++V  GA  +   H +  GVQ +        F++P+    
Sbjct: 195  RDWVLTAAHCFPERNRVLSRWRVFAGAVAQTSPHGVQLGVQAVIYHGGYLPFRDPNSEEN 254

Query: 956  --DIALLKLSSPAVITDKVIPACLPTPNYVVADRTACYITGWGETKGTYG--AGLLKEAR 1123
              DIAL+ LS    +T+ + P CLP     + D   C +TGWG T+  YG  AG+L+EAR
Sbjct: 255  SNDIALVHLSGTLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQEAR 313

Query: 1124 LPVIENKVCNRYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEK----DKYILQG 1291
            +P+I N VCN  ++ G ++ P   CAG+  GGID+CQGDSGGP VC +      ++ L G
Sbjct: 314  VPIISNDVCNGPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCG 373

Query: 1292 VTSWGLGCALPNKPGVYVRVXRFVTWIEEIMR 1387
            + SWG GCAL  KPGVY +V  F  WI + ++
Sbjct: 374  IVSWGTGCALAQKPGVYTKVSDFREWIFQAIK 405


>ref|XP_886646.1| PREDICTED: similar to Serine protease hepsin (Transmembrane protease,
            serine 1) isoform 3 [Bos taurus]
          Length = 434

 Score =  200 bits (508), Expect = 3e-51
 Identities = 124/332 (37%), Positives = 174/332 (52%), Gaps = 20/332 (6%)
 Frame = +2

Query: 452  VAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCD 631
            VAG+ C+E         S     T    G    +C      D G   +     ++   CD
Sbjct: 85   VAGLSCEEMGFLRALDFSELDVRTAGANGTSGFFCV-----DEGRLPHARRLLEVLSVCD 139

Query: 632  VPQ---CETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLIS 802
             P+     TS  DCG  K+       R+VGG  +    WPWQ+SLR   G H CGG+++S
Sbjct: 140  CPRGRFLATSCQDCGHRKLPVD----RIVGGQDTSLGRWPWQVSLRYD-GAHLCGGSVLS 194

Query: 803  PEWVLTAKHCL-EKSSSPSSYKVILGAHEE---HHLGEGVQEIDVSK---LFKEPSGA-- 955
             +WVLTA HC  E++   S ++V  GA  +   H +  GVQ +        F++P+    
Sbjct: 195  RDWVLTAAHCFPERNRVLSRWRVFAGAVAQTSPHGVQLGVQAVIYHGGYLPFRDPNSEEN 254

Query: 956  --DIALLKLSSPAVITDKVIPACLPTPNYVVADRTACYITGWGETKGTYG--AGLLKEAR 1123
              DIAL+ LS    +T+ + P CLP     + D   C +TGWG T+  YG  AG+L+EAR
Sbjct: 255  SNDIALVHLSGTLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQEAR 313

Query: 1124 LPVIENKVCNRYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEK----DKYILQG 1291
            +P+I N VCN  ++ G ++ P   CAG+  GGID+CQGDSGGP VC +      ++ L G
Sbjct: 314  VPIISNDVCNGPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCG 373

Query: 1292 VTSWGLGCALPNKPGVYVRVXRFVTWIEEIMR 1387
            + SWG GCAL  KPGVY +V  F  WI + ++
Sbjct: 374  IVSWGTGCALAQKPGVYTKVSDFREWIFQAIK 405


>ref|XP_618102.2| PREDICTED: similar to Transmembrane protease, serine 3 [Bos taurus]
          Length = 787

 Score =  200 bits (508), Expect = 3e-51
 Identities = 106/235 (45%), Positives = 141/235 (60%), Gaps = 7/235 (2%)
 Frame = +2

Query: 701  RVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKV---- 868
            R+VGG  S    WPWQ SL+ + G H CGG++I+P WV+TA HC+     P S+ +    
Sbjct: 250  RIVGGNTSSLAQWPWQASLQFQ-GYHLCGGSVITPLWVVTAAHCVYDLYLPKSWTIQVGL 308

Query: 869  --ILGAHEEHHLGEGVQEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLPTPNYVV 1042
              +L +    HL E +  I  SK   +  G DIAL+KL+ P    +   P CLP      
Sbjct: 309  VSLLDSPAPSHLVEKI--IYHSKYKPKRLGNDIALMKLAGPVTFNEMTQPVCLPNSEENF 366

Query: 1043 ADRTACYITGWGETK-GTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAGHLAGG 1219
             D   C+ +GWG T+ G   + +L  A +P+I NKVCN  +  GG +SP+ LCAG+L GG
Sbjct: 367  PDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKVCNHRDVYGGIISPSMLCAGYLKGG 426

Query: 1220 IDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIM 1384
            +DSCQGDSGGPLVC E+  + L G TS+G+GCA  NKPGVY R+  F+ WI E M
Sbjct: 427  VDSCQGDSGGPLVCQERRVWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQM 481


>ref|NP_001014868.1| hyaluronan binding protein 2 [Bos taurus]
          Length = 558

 Score =  198 bits (504), Expect = 8e-51
 Identities = 128/373 (34%), Positives = 180/373 (48%), Gaps = 42/373 (11%)
 Frame = +2

Query: 398  EDCMFGNGKRYRGKRATTVAGVPCQEWAAQE--PHRHSIFTPETNPRAGLEKNYCRNPDG 571
            +DC   +G  YRG+ + T+    C  W +      ++++F  +       E N+CRNPDG
Sbjct: 190  DDCYVDDGYSYRGRVSKTIHQHTCLYWNSHLLLQEKYNMFMEDAEAHGIGEHNFCRNPDG 249

Query: 572  DDNGPWCY--TTNPQKLFDYCDVPQCETSSF------------------DCGKPKMEPKK 691
            D   PWC+    N +  ++YCDVP C                        CG+ ++  KK
Sbjct: 250  DKK-PWCFIKVNNVKVKWEYCDVPACSALDVANPEGRPTEPLTKFPEFGSCGRTEIAEKK 308

Query: 692  CPARVVGGCVSIPHSWPWQISLRRRYG-------GHFCGGTLISPEWVLTAKHCLEKSSS 850
               R+ GG  S     PWQ SL+           GH+CGG LI P WVLTA HC E  + 
Sbjct: 309  VK-RIFGGFKSTAGKHPWQASLQTSLRLTVSTPQGHYCGGALIHPCWVLTAAHCTEIKTK 367

Query: 851  PSSYKVILGAHEEHHLGEGVQEIDVSKLFK--------EPSGADIALLKLSSP----AVI 994
                KV+LG  +        Q   V K+FK        +    DIALLKL       A+ 
Sbjct: 368  --YLKVVLGDQDLTKTEFHEQSFGVQKIFKYSHYIEIDDIPYNDIALLKLKPVDGHCALE 425

Query: 995  TDKVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLGG 1174
            +  V   CLP   ++    T CYI+GWG T+   G+  L +A++ +I N +CN  +    
Sbjct: 426  SKYVKTVCLPDGPFLSG--TECYISGWGVTETGEGSRHLLDAKVKLISNTICNSRQLYDH 483

Query: 1175 KVSPNELCAGHL-AGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRV 1351
             +  N +CAG+L   G DSCQGDSGGPL C +     + G+ SWGL C    +PGVY +V
Sbjct: 484  SIDDNMICAGNLQKPGQDSCQGDSGGPLTCEKDGTSYIYGIVSWGLECG--KRPGVYTQV 541

Query: 1352 XRFVTWIEEIMRR 1390
             +F+TWI+  M +
Sbjct: 542  TKFLTWIKATMEK 554



 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 42/132 (31%), Positives = 60/132 (45%), Gaps = 16/132 (12%)
 Frame = +2

Query: 92  DCYRGNGESYRGTSSTTITGRKCQSWVS--MTPHRHEKTPGNFPNAGL-TMNYCRNPDAD 262
           DCY  +G SYRG  S TI    C  W S  +   ++     +    G+   N+CRNPD D
Sbjct: 191 DCYVDDGYSYRGRVSKTIHQHTCLYWNSHLLLQEKYNMFMEDAEAHGIGEHNFCRNPDGD 250

Query: 263 KSPWCY--TTDPRVRWEYCNLKKCSETE---------QQVTNFPAIVQVPSVEDLSEDC- 406
           K PWC+    + +V+WEYC++  CS  +         + +T FP        E   +   
Sbjct: 251 KKPWCFIKVNNVKVKWEYCDVPACSALDVANPEGRPTEPLTKFPEFGSCGRTEIAEKKVK 310

Query: 407 -MFGNGKRYRGK 439
            +FG  K   GK
Sbjct: 311 RIFGGFKSTAGK 322


>ref|XP_607216.2| PREDICTED: similar to protease, serine, 33 [Bos taurus]
          Length = 369

 Score =  193 bits (491), Expect = 2e-49
 Identities = 110/280 (39%), Positives = 153/280 (54%), Gaps = 21/280 (7%)
 Frame = +2

Query: 599  TNPQKLFDYCDVPQCETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGH 778
            T PQ     C  P   +S   CG+P++      +R+VGG  +    WPWQ S++ R G H
Sbjct: 15   TAPQACLAGCYGPS-SSSGPTCGQPRVS-----SRIVGGRDARAGEWPWQASIQHR-GAH 67

Query: 779  FCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEG--------VQEIDVSKL 934
             CGG+LI+P+WVLTA HC  + + P+ Y+V LGA    HLG          V+ + +   
Sbjct: 68   VCGGSLIAPQWVLTAAHCFPRKALPADYRVRLGAP---HLGPSSPPALLAPVRRVLLPPD 124

Query: 935  FKEPSG-ADIALLKLSSPAVITDKVIPACLPTPNYVVADRTACYITGWGETKGTYGAGL- 1108
            + E     D+ALL L  P  ++ +V P CLP P       T C++TGWG  +   G  L 
Sbjct: 125  YSEDGAHGDLALLLLRRPTPLSTRVQPVCLPEPGARPPPGTPCWVTGWGSLRP--GVPLP 182

Query: 1109 ----LKEARLPVIENKVCNRYEYLGGKVS-------PNELCAGHLAGGIDSCQGDSGGPL 1255
                L+  R+P+++   C+   +LG  V        P  LCAG++ G  D+CQGDSGGPL
Sbjct: 183  EWRPLQGVRVPLLDAHTCDHLYHLGTDVPRAEHIVLPGSLCAGYVGGQKDACQGDSGGPL 242

Query: 1256 VCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIE 1375
            VC +  ++IL GV SWG GCALPN+PGVY  V  +  WI+
Sbjct: 243  VCMKSGRWILVGVVSWGKGCALPNRPGVYTNVATYSPWIQ 282


  Database: RefSeqBP
    Posted date:  Aug 1, 2006  7:14 PM
  Number of letters in database: 16,112,626
  Number of sequences in database:  33,508
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,375,323
Number of Sequences: 33508
Number of extensions: 1790509
Number of successful extensions: 7955
Number of sequences better than 1.0e-05: 10
Number of HSP's better than  0.0 without gapping: 5309
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7393
length of database: 16,112,626
effective HSP length: 105
effective length of database: 12,594,286
effective search space used: 4634697248
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)


Search to RefSeqSP
BLASTX 2.2.10 [Oct-19-2004]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20060611C-000407
         (1422 letters)

Database: RefSeqSP 
           1040 sequences; 434,620 total letters

Searching...done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_999219.1| T-plasminogen activator [Sus scrofa]                 239   9e-65
Alignment   gi|NP_999407.1| factor XII [Sus scrofa]                              189   1e-49
Alignment   gi|NP_999110.1| plasminogen activator [Sus scrofa]                   189   1e-49
Alignment   gi|NP_999356.1| tryptase [Sus scrofa]                                184   3e-48
Alignment   gi|NP_001001259.1| enteropeptidase, light chain (L chain) [Sus ...   182   2e-47
Alignment   gi|NP_999274.1| pancreatic elastase II [Sus scrofa]                  175   2e-45
Alignment   gi|NP_999239.1| kallikrein [Sus scrofa]                              171   3e-44
Alignment   gi|NP_999198.1| preproacrosin [Sus scrofa]                           166   2e-42
Alignment   gi|NP_998959.1| tryptase [Sus scrofa]                                162   2e-41
Alignment   gi|NP_998988.1| pancreatic elastase I [Sus scrofa]                   158   3e-40

>ref|NP_999219.1| T-plasminogen activator [Sus scrofa]
          Length = 562

 Score =  239 bits (611), Expect = 9e-65
 Identities = 164/466 (35%), Positives = 226/466 (48%), Gaps = 35/466 (7%)
 Frame = +2

Query: 95   CYRGNGESYRGTSSTTITGRKCQSW----VSMTPHRHEKTPGNFPNA---GL-TMNYCRN 250
            CY   G +YRGT STT +G +C +W    ++  P+      G  P+A   GL   NYCRN
Sbjct: 127  CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYN-----GRRPDAVKLGLGNHNYCRN 181

Query: 251  PDADKSPWCYTTDP-RVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKR 427
            PD D  PWCY     +   ++C+   C++ +                   E+C  G G  
Sbjct: 182  PDKDSKPWCYIFKAEKYSPDFCSTPACTKEK-------------------EECYTGKGLD 222

Query: 428  YRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRA-GLEK-NYCRNPDGDDNGPWCYTT 601
            YRG R+ T++G  C  W +            +N +  GL K NYCRNPDGD   PWC+  
Sbjct: 223  YRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ-PWCHVL 281

Query: 602  NPQKL-FDYCDVPQCETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISL----RRR 766
               KL ++YCD+PQC T    CG  +   K+   R+ GG  +   S PWQ ++    RR 
Sbjct: 282  KDHKLTWEYCDLPQCVT----CGLRQY--KEPQFRIKGGLYADITSHPWQAAIFVKNRRS 335

Query: 767  YGGHF-CGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLF-- 937
             G  F CGG LIS  WVL+A HC ++   P   +V+LG       GE  Q  +V K    
Sbjct: 336  PGERFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVH 395

Query: 938  ----KEPSGADIALLKLSSPAVI----TDKVIPACLPTPNYVVADRTACYITGWG--ETK 1087
                 +    DIALL+L S ++     +D V   CLP  N  + D T C ++G+G  E  
Sbjct: 396  KEFDDDTYDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEAS 455

Query: 1088 GTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAGHLAGG------IDSCQGDSGG 1249
              + +  LKEA + +  +  C         ++ N LCAG    G       D+CQGDSGG
Sbjct: 456  SPFYSERLKEAHVRLYPSSRCTSKHLFNKTITNNMLCAGDTRSGGDNANLHDACQGDSGG 515

Query: 1250 PLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIMR 1387
            PLVC + +   L GV SWGLGC   + PGVY +V  ++ WI +  R
Sbjct: 516  PLVCMKGNHMTLVGVISWGLGCGQKDVPGVYTKVTNYLNWIRDNTR 561



 Score = 74.3 bits (181), Expect = 6e-15
 Identities = 37/91 (40%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
 Frame = +2

Query: 68  PEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTM---N 238
           P  T   ++CY G G  YRGT S T++G  C  W S+       T  N     L +   N
Sbjct: 206 PACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHN 265

Query: 239 YCRNPDADKSPWCYT-TDPRVRWEYCNLKKC 328
           YCRNPD D  PWC+   D ++ WEYC+L +C
Sbjct: 266 YCRNPDGDTQPWCHVLKDHKLTWEYCDLPQC 296


>ref|NP_999407.1| factor XII [Sus scrofa]
          Length = 616

 Score =  189 bits (481), Expect = 1e-49
 Identities = 134/449 (29%), Positives = 195/449 (43%), Gaps = 21/449 (4%)
 Frame = +2

Query: 95   CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMN-YCRNPDADKSP 271
            CY   G SYRG + TT++G  CQ W S   +    T     N GL  + +CRNPD D  P
Sbjct: 217  CYSDRGLSYRGMAQTTLSGAPCQPWASEATY-WNMTAEQALNWGLGDHAFCRNPDNDTRP 275

Query: 272  WCYT-TDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRGKRAT 448
            WC+     ++ W+YC L +C     +        Q PS                      
Sbjct: 276  WCFVWRGDQLSWQYCRLARCQAPIGEAPPILTPTQSPS---------------------- 313

Query: 449  TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 628
                         E     + + E  P         + P  +    WC     +      
Sbjct: 314  -------------EHQDSPLLSREPQPTT-------QTPSQNLTSAWCAPPEQRG----- 348

Query: 629  DVPQCETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPE 808
              P        CG+   +      R+VGG V++P + P+  +L   +G +FC G+LI+P 
Sbjct: 349  --PLPSAGLVGCGQRLRKRLSSLNRIVGGLVALPGAHPYIAAL--YWGQNFCAGSLIAPC 404

Query: 809  WVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLFKEPSGA------DIALL 970
            WVLTA HCL+   +P    V+LG    +   E  Q + V       S +      D+AL+
Sbjct: 405  WVLTAAHCLQNRPAPEELTVVLGQDRHNQSCEQCQTLAVRSYRLHESYSPKTYQHDLALV 464

Query: 971  KLSSP-----AVITDKVIPACLP--TPNYVVADRTACYITGWG---ETKGTYGAGLLKEA 1120
            +L        A  +  V P CLP    +    +   C + GWG   E    Y +  L+EA
Sbjct: 465  RLKETADGCCAHPSPFVQPVCLPRSVASSAEPEGALCEVAGWGHQFEGAEEY-SSFLQEA 523

Query: 1121 RLPVIENKVCNRYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEKD---KYILQG 1291
            ++P+I  + C+  +  G   +P  LCAG L GG D+CQGDSGGPLVC ++    + +L+G
Sbjct: 524  QVPLISPERCSAADVHGAAFTPGMLCAGFLEGGTDACQGDSGGPLVCEDETAERQLVLRG 583

Query: 1292 VTSWGLGCALPNKPGVYVRVXRFVTWIEE 1378
            + SWG GC    KPGVY  V  ++ WI+E
Sbjct: 584  IVSWGSGCGDRLKPGVYTDVANYLAWIQE 612


>ref|NP_999110.1| plasminogen activator [Sus scrofa]
          Length = 442

 Score =  189 bits (481), Expect = 1e-49
 Identities = 126/368 (34%), Positives = 172/368 (46%), Gaps = 40/368 (10%)
 Frame = +2

Query: 389  DLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNP-RAGLEK-NYCRN 562
            D S+ C  GNG  YRGK  T   G PC  W +     ++      +  + GL K NYCRN
Sbjct: 67   DTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRN 126

Query: 563  PDGDDNGPWCYT-TNPQKLFDYCDVPQC-------------------ETSSFDCGKPKME 682
            PD +   PWCY     ++L   C VP C                   E   F CG+  + 
Sbjct: 127  PD-NQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQKALR 185

Query: 683  PKKCPARVVGGCVSIPHSWPWQISLRRRYGG----HFCGGTLISPEWVLTAKHCLEKSSS 850
            P+    ++VGG  +   + PW  ++ RR+ G    + CGG+LISP WV++A HC      
Sbjct: 186  PR---FKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQH 242

Query: 851  PSSYKVILGAHEEHHLGEGVQEIDVSKLFKEPSGA--------DIALLKLSSP----AVI 994
               Y V LG    H    G  + +V KL      +        DIALLK+ +     A  
Sbjct: 243  KEDYIVYLGRQTLHSSTHGEMKFEVEKLILHEDYSADSLAHHNDIALLKIRTDKGQCAQP 302

Query: 995  TDKVIPACLPTPNYVVADRTACYITGWG-ETKGTY-GAGLLKEARLPVIENKVCNRYEYL 1168
            +  +   CLP  N       +C I G+G E    Y     LK   + ++ ++ C +  Y 
Sbjct: 303  SRSIQTICLPPVNGDAHFGASCEIVGFGKEDPSDYLYPEQLKMTVVKLVSHRECQQPHYY 362

Query: 1169 GGKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVR 1348
            G +V+   LCA       DSCQGDSGGPLVC  + +  L G+ SWG  CA+ +KPGVY R
Sbjct: 363  GSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSTQGRLTLTGIVSWGRECAMKDKPGVYTR 422

Query: 1349 VXRFVTWI 1372
            V RF+TWI
Sbjct: 423  VSRFLTWI 430



 Score = 61.2 bits (147), Expect = 6e-11
 Identities = 44/147 (29%), Positives = 58/147 (39%), Gaps = 8/147 (5%)
 Frame = +2

Query: 86  AQDCYRGNGESYRGTSSTTITGRKCQSWVSMT---PHRHEKTPGNFPNAGLTMNYCRNPD 256
           +Q C+ GNG SYRG ++T   GR C  W S T      H   P          NYCRNPD
Sbjct: 69  SQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPD 128

Query: 257 ADKSPWCYT-TDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYR 433
             + PWCY     +   + C +  CS  E     +       + E +   C    G++  
Sbjct: 129 NQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQC----GQKAL 184

Query: 434 GKRATTVAG----VPCQEWAAQEPHRH 502
             R   V G    +  Q W A    RH
Sbjct: 185 RPRFKIVGGKSTTIENQPWFAAIYRRH 211


>ref|NP_999356.1| tryptase [Sus scrofa]
          Length = 275

 Score =  184 bits (468), Expect = 3e-48
 Identities = 104/250 (41%), Positives = 141/250 (56%), Gaps = 19/250 (7%)
 Frame = +2

Query: 698  ARVVGGCVSIPHSWPWQISLR--RRYGGHFCGGTLISPEWVLTAKHCL-EKSSSPSSYKV 868
            A +VGG  +  H WPWQ+SLR   +Y  HFCGG+LI P+WVLTA HC   + + P   +V
Sbjct: 29   AGIVGGKEAPGHKWPWQVSLRCLDQYWKHFCGGSLIHPQWVLTAAHCFGPEKADPLYIRV 88

Query: 869  ILGAHEEHHLGEGVQEIDVSKLFKEPS------GADIALLKLSSPAVITDKVIPACLPTP 1030
             LG   E HL    + + VS++   P+      GADIALL+L  P  ++  V P  LP  
Sbjct: 89   QLG---EQHLYYQDRLLLVSRIIVHPNYYDEVNGADIALLELEDPVNLSSHVQPVTLPPA 145

Query: 1031 NYVVADRTACYITGWGETKGTYGAGL---LKEARLPVIENKVCNRYEYLGGKVSPN---- 1189
            +      T C++TGWG+    +       LK+ R+P++EN  C+   +LG     N    
Sbjct: 146  SETFPKGTRCWVTGWGDVHSGWPLPPPYPLKQVRVPIVENSECDMQYHLGLSTGDNIPIV 205

Query: 1190 ---ELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRF 1360
                LCAG  + G DSCQGDSGGPLVC     ++  GV SWG GCALPN+PG+Y RV  +
Sbjct: 206  RDDMLCAG--SEGHDSCQGDSGGPLVCRVNGTWLQAGVVSWGEGCALPNRPGIYTRVTHY 263

Query: 1361 VTWIEEIMRR 1390
            + WI + + R
Sbjct: 264  LDWIHQCIPR 273


>ref|NP_001001259.1| enteropeptidase, light chain (L chain) [Sus scrofa]
          Length = 1034

 Score =  182 bits (461), Expect = 2e-47
 Identities = 107/282 (37%), Positives = 161/282 (57%), Gaps = 13/282 (4%)
 Frame = +2

Query: 578  NGPWCYTTNPQKLFDYCDVPQCETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISL 757
            NG    T + Q   D   + QC   S  CGK ++  +  P ++VGG  S   +WPW ++L
Sbjct: 761  NGSLILTASEQCFEDSLILLQCNHKS--CGKKQVAQEVSP-KIVGGNDSREGAWPWVVAL 817

Query: 758  RRRYGGHF-CGGTLISPEWVLTAKHCLE-KSSSPSSYKVILGAHEEHHLGEG------VQ 913
               Y G   CG +L+S +W+++A HC+  ++  PS +K ILG H   +L         + 
Sbjct: 818  Y--YNGQLLCGASLVSRDWLVSAAHCVYGRNLEPSKWKAILGLHMTSNLTSPQIVTRLID 875

Query: 914  EIDVSKLF-KEPSGADIALLKLSSPAVITDKVIPACLPTPNYVVADRTACYITGWGET-- 1084
            EI ++  + +    +DIA++ L      TD + P CLP  N V      C I GWG+   
Sbjct: 876  EIVINPHYNRRRKDSDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRICSIAGWGKVIY 935

Query: 1085 KGTYGAGLLKEARLPVIENKVCNRY--EYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLV 1258
            +G+  A +L+EA +P++ N+ C +   EY    ++ N +CAG+  GGIDSCQGDSGGPL+
Sbjct: 936  QGS-PADILQEADVPLLSNEKCQQQMPEY---NITENMMCAGYEEGGIDSCQGDSGGPLM 991

Query: 1259 CFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIM 1384
            C E ++++L GVTS+G  CALPN+PGVY RV +F  WI+  +
Sbjct: 992  CLENNRWLLAGVTSFGYQCALPNRPGVYARVPKFTEWIQSFL 1033


>ref|NP_999274.1| pancreatic elastase II [Sus scrofa]
          Length = 269

 Score =  175 bits (444), Expect = 2e-45
 Identities = 104/263 (39%), Positives = 146/263 (55%), Gaps = 16/263 (6%)
 Frame = +2

Query: 653  SFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGG---HFCGGTLISPEWVLTA 823
            +  CG P   P+    RVVGG  + P+SWPWQ+SL+    G   H CGGTL+   WVLTA
Sbjct: 14   ALSCGLPANLPQL--PRVVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTA 71

Query: 824  KHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLFKEP--------SGADIALLKLS 979
             HC+   SS  +Y+V+LG H       G   + VSKL            +G DIALLKL+
Sbjct: 72   AHCI---SSSRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLA 128

Query: 980  SPAVITDKVIPACLPTPNYVVADRTACYITGWGETKGTYGAG--LLKEARLPVIENKVCN 1153
            SP  +TDK+   CLP    ++ +   CY+TGWG  + T GA   +L++ +L V++   C+
Sbjct: 129  SPVSLTDKIQLGCLPAAGTILPNNYVCYVTGWGRLQ-TNGASPDILQQGQLLVVDYATCS 187

Query: 1154 RYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLVC-FEKDKYILQGVTSWG--LGCALP 1324
            +  + G  V  N +CAG   G I SC GDSGGPL C     ++ + G+ S+G  LGC   
Sbjct: 188  KPGWWGSTVKTNMICAGG-DGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYY 246

Query: 1325 NKPGVYVRVXRFVTWIEEIMRRN 1393
            +KP V+ RV  ++ WI  ++  N
Sbjct: 247  HKPSVFTRVSNYIDWINSVIANN 269


>ref|NP_999239.1| kallikrein [Sus scrofa]
          Length = 643

 Score =  171 bits (434), Expect = 3e-44
 Identities = 96/240 (40%), Positives = 136/240 (56%), Gaps = 10/240 (4%)
 Frame = +2

Query: 689  KCPARVVGGCVSIPHSWPWQISLRR--RYGGHFCGGTLISPEWVLTAKHCLEKSSSPSSY 862
            K   R+VGG  S    WPWQ+SL+   R   H CGG++I  +WVLTA HC +  S P  +
Sbjct: 394  KANTRIVGGTDSFLGEWPWQVSLQAKLRAQNHLCGGSIIGHQWVLTAAHCFDGLSLPDIW 453

Query: 863  KVILGAHEEHHLGEG-----VQEIDVSKLFKE-PSGADIALLKLSSPAVITDKVIPACLP 1024
            ++  G      + +      V+EI + + +K   SG DIALLKL +P   TD   P CLP
Sbjct: 454  RIYGGILNISEITKETPFSQVKEIIIHQNYKILESGHDIALLKLETPLNYTDFQKPICLP 513

Query: 1025 TPNYVVADRTACYITGWG--ETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELC 1198
            + +      T C++TGWG  E KG     +L++  +P++ N+ C +  Y   K+S   +C
Sbjct: 514  SRDDTNVVYTNCWVTGWGFTEEKGEI-QNILQKVNIPLVSNEECQK-SYRDHKISKQMIC 571

Query: 1199 AGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEE 1378
            AG+  GG D+C+G+SGGPLVC     + L G TSWG GCA   +PGVY +V  ++ WI E
Sbjct: 572  AGYKEGGKDACKGESGGPLVCKYNGIWHLVGTTSWGEGCARREQPGVYTKVIEYMDWILE 631


>ref|NP_999198.1| preproacrosin [Sus scrofa]
          Length = 400

 Score =  166 bits (419), Expect = 2e-42
 Identities = 96/261 (36%), Positives = 148/261 (56%), Gaps = 24/261 (9%)
 Frame = +2

Query: 662  CGKPKMEPKKCPARVVGGCVSIPHSWPWQISLR-------RRYGGHFCGGTLISPEWVLT 820
            CG    +  +   RVVGG  + P +WPW +SL+       RRY  H CGG L++  WVLT
Sbjct: 25   CGLRFRQKLESGMRVVGGMSAEPGAWPWMVSLQIFMYHNNRRY--HTCGGILLNSHWVLT 82

Query: 821  AKHCLEKSSSPSSYKVILGAHE-----EHHLGEGVQEIDVSKLF---KEPSGA---DIAL 967
            A HC +     + +++I GA+E        +   +QE  V ++    K  SG    DIAL
Sbjct: 83   AAHCFKNKKKVTDWRLIFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIAL 142

Query: 968  LKLSSPAVITDKVIPACLPT--PNYVVADRTACYITGWG--ETKGTYGAGLLKEARLPVI 1135
            +K++ P      + P CLP        A +T C++TGWG  + KG   +  L+EAR+ +I
Sbjct: 143  IKITPPVPCGPFIGPGCLPQFKAGPPRAPQT-CWVTGWGYLKEKGPRTSPTLQEARVALI 201

Query: 1136 ENKVCNRYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEK--DKYILQGVTSWGL 1309
            + ++CN  ++  G+V+   +CAG+  G ID+CQGDSGGPL+C ++  + +++ G+TSWG+
Sbjct: 202  DLELCNSTQWYNGRVTSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGV 261

Query: 1310 GCALPNKPGVYVRVXRFVTWI 1372
            GCA   +PGVY     ++ WI
Sbjct: 262  GCARAKRPGVYTSTWPYLNWI 282


>ref|NP_998959.1| tryptase [Sus scrofa]
          Length = 277

 Score =  162 bits (410), Expect = 2e-41
 Identities = 96/260 (36%), Positives = 140/260 (53%), Gaps = 19/260 (7%)
 Frame = +2

Query: 671  PKMEPKKCPARVVGGCVSIPHSWPWQISLRR---RYGG--HFCGGTLISPEWVLTAKHCL 835
            P   P+     +VGG       +PWQ+SLR    + G   H CGG+L+ P+WVLTA HC+
Sbjct: 20   PGRGPRHELVGIVGGHDVSTWKYPWQVSLRSYRVKLGRWMHHCGGSLVHPQWVLTAAHCV 79

Query: 836  EKSS-SPSSYKVILGAHEEHHLGEGVQEIDVSKLFKEPS-------GADIALLKLSSPAV 991
            +  +  P   +V +G   +  L +G Q   V ++ + P        GADIALL+L +P  
Sbjct: 80   DSHNLKPQDVRVQVG---QLKLYDGDQLTKVKQIIRHPKYLGFAKGGADIALLQLEAPLT 136

Query: 992  ITDKVIPACLPTPNYVVADRTACYITGWGETKGTYGAGL---LKEARLPVIENKVCNRYE 1162
            ++ +V     P+    V     C +TGWG  K          L+E  +P++ NKVCN++ 
Sbjct: 137  LSARVNVVGTPSATLKVPKGKRCSVTGWGNIKHNLSLPPPYHLQEVEVPIVANKVCNKHY 196

Query: 1163 YLGGKVSP---NELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKP 1333
              G    P   + LCAG  + G+DSCQGDSGGPL+C     ++  G+ SWG GC L N P
Sbjct: 197  RTGPNSKPIKADMLCAG--SKGLDSCQGDSGGPLMCSWNGTWVQVGIVSWGRGCGLHNFP 254

Query: 1334 GVYVRVXRFVTWIEEIMRRN 1393
            GVY+RV  +V+WI + + R+
Sbjct: 255  GVYIRVMSYVSWIYQYVPRS 274


>ref|NP_998988.1| pancreatic elastase I [Sus scrofa]
          Length = 266

 Score =  158 bits (399), Expect = 3e-40
 Identities = 95/248 (38%), Positives = 137/248 (55%), Gaps = 16/248 (6%)
 Frame = +2

Query: 698  ARVVGGCVSIPHSWPWQISLRRRYGG---HFCGGTLISPEWVLTAKHCLEKSSSPSSYKV 868
            ARVVGG  +  +SWP QISL+ R G    H CGGTLI   WV+TA HC+++  +   ++V
Sbjct: 25   ARVVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELT---FRV 81

Query: 869  ILGAHEEHHLGEGVQEIDVSKLFKEP--------SGADIALLKLSSPAVITDKVIPACLP 1024
            ++G H  +      Q + V K+   P        +G DIALL+L     +   V    LP
Sbjct: 82   VVGEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLGQSVTLNSYVQLGVLP 141

Query: 1025 TPNYVVADRTACYITGWGETKGTYG--AGLLKEARLPVIENKVCNRYEYLGGKVSPNELC 1198
                ++A+ + CYITGWG T+ T G  A  L++A LP ++  + +   Y G  V  + +C
Sbjct: 142  RAGTILANNSPCYITGWGLTR-TNGQLAQTLQQAYLPTVDYAILSSSSYWGSTVKNSMVC 200

Query: 1199 AGHLAGGIDS-CQGDSGGPLVCFEKDKYILQGVTSW--GLGCALPNKPGVYVRVXRFVTW 1369
            AG    G+ S CQGDSGGPL C    +Y + GVTS+   LGC +  KP V+ RV  +++W
Sbjct: 201  AG--GDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISW 258

Query: 1370 IEEIMRRN 1393
            I  ++  N
Sbjct: 259  INNVIASN 266


  Database: RefSeqSP
    Posted date:  Aug 1, 2006  7:14 PM
  Number of letters in database: 434,620
  Number of sequences in database:  1040
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,586,978
Number of Sequences: 1040
Number of extensions: 46371
Number of successful extensions: 283
Number of sequences better than 1.0e-05: 10
Number of HSP's better than  0.0 without gapping: 149
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 209
length of database: 434,620
effective HSP length: 80
effective length of database: 351,420
effective search space used: 138108060
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)


Search to RefSeqHP
BLASTX 2.2.10 [Oct-19-2004]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20060611C-000407
         (1422 letters)

Database: RefSeqHP 
           39,411 sequences; 17,774,539 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_000292.1| plasminogen [Homo sapiens]                           821   0.0  
Alignment   gi|NP_005568.1| lipoprotein, Lp(a) [Homo sapiens]                    730   0.0  
Alignment   gi|XP_946885.1| PREDICTED: similar to Apolipoprotein(a) precurs...   615   e-176
Alignment   gi|XP_931416.1| PREDICTED: similar to Apolipoprotein(a) precurs...   615   e-176
Alignment   gi|NP_066278.2| macrophage stimulating 1 (hepatocyte growth fac...   345   5e-95
Alignment   gi|NP_001010932.1| hepatocyte growth factor isoform 3 precursor...   323   3e-88
Alignment   gi|NP_000592.3| hepatocyte growth factor isoform 1 preproprotei...   323   3e-88
Alignment   gi|NP_127509.1| plasminogen activator, tissue type isoform 3 pr...   246   3e-65
Alignment   gi|NP_000921.1| plasminogen activator, tissue type isoform 1 pr...   246   3e-65
Alignment   gi|NP_892028.1| hepsin (transmembrane protease, serine 1) [Homo...   210   3e-54

>ref|NP_000292.1| plasminogen [Homo sapiens]
          Length = 810

 Score =  821 bits (2121), Expect = 0.0
 Identities = 376/465 (80%), Positives = 405/465 (87%), Gaps = 1/465 (0%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
            YCKIPSC SS  STE L    PPE TPV QDCY G+G+SYRGTSSTT TG+KCQSW SMT
Sbjct: 346  YCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMT 405

Query: 182  PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFP 361
            PHRH+KTP N+PNAGLTMNYCRNPDADK PWC+TTDP VRWEYCNLKKCS TE  V   P
Sbjct: 406  PHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPP 465

Query: 362  AIVQVPSVEDLSE-DCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAG 538
             +V +P VE  SE DCMFGNGK YRGKRATTV G PCQ+WAAQEPHRHSIFTPETNPRAG
Sbjct: 466  PVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAG 525

Query: 539  LEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETSSFDCGKPKMEPKKCPARVVGGC 718
            LEKNYCRNPDGD  GPWCYTTNP+KL+DYCDVPQC   SFDCGKP++EPKKCP RVVGGC
Sbjct: 526  LEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGC 585

Query: 719  VSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHL 898
            V+ PHSWPWQ+SLR R+G HFCGGTLISPEWVLTA HCLEKS  PSSYKVILGAH+E +L
Sbjct: 586  VAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNL 645

Query: 899  GEGVQEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLPTPNYVVADRTACYITGWG 1078
               VQEI+VS+LF EP+  DIALLKLSSPAVITDKVIPACLP+PNYVVADRT C+ITGWG
Sbjct: 646  EPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWG 705

Query: 1079 ETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLV 1258
            ET+GT+GAGLLKEA+LPVIENKVCNRYE+L G+V   ELCAGHLAGG DSCQGDSGGPLV
Sbjct: 706  ETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLV 765

Query: 1259 CFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIMRRN 1393
            CFEKDKYILQGVTSWGLGCA PNKPGVYVRV RFVTWIE +MR N
Sbjct: 766  CFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN 810



 Score =  209 bits (531), Expect = 6e-54
 Identities = 96/217 (44%), Positives = 125/217 (57%), Gaps = 4/217 (1%)
 Frame = +2

Query: 5   CKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTP 184
           C IP C +            PP   P  Q C +G GE+YRG  + T++G  CQ W + TP
Sbjct: 257 CDIPRCTTP-----------PPSSGPTYQ-CLKGTGENYRGNVAVTVSGHTCQHWSAQTP 304

Query: 185 HRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCS----ETEQQVT 352
           H H +TP NFP   L  NYCRNPD  ++PWC+TT+ +VRWEYC +  C      TEQ   
Sbjct: 305 HTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTEQLAP 364

Query: 353 NFPAIVQVPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPR 532
             P     P +  + +DC  G+G+ YRG  +TT  G  CQ W++  PHRH   TPE  P 
Sbjct: 365 TAP-----PELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQ-KTPENYPN 418

Query: 533 AGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
           AGL  NYCRNPD  D GPWC+TT+P   ++YC++ +C
Sbjct: 419 AGLTMNYCRNPDA-DKGPWCFTTDPSVRWEYCNLKKC 454



 Score =  187 bits (474), Expect = 2e-47
 Identities = 83/188 (44%), Positives = 112/188 (59%)
 Frame = +2

Query: 89  QDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKS 268
           ++C   +GE+Y G  S T++G +CQ+W S +PH H   P  FPN  L  NYCRNPD +  
Sbjct: 183 EECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELR 242

Query: 269 PWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRGKRAT 448
           PWC+TTDP  RWE C++ +C+               P     +  C+ G G+ YRG  A 
Sbjct: 243 PWCFTTDPNKRWELCDIPRCTTP-------------PPSSGPTYQCLKGTGENYRGNVAV 289

Query: 449 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 628
           TV+G  CQ W+AQ PH H+  TPE  P   L++NYCRNPDG    PWC+TTN Q  ++YC
Sbjct: 290 TVSGHTCQHWSAQTPHTHN-RTPENFPCKNLDENYCRNPDG-KRAPWCHTTNSQVRWEYC 347

Query: 629 DVPQCETS 652
            +P C++S
Sbjct: 348 KIPSCDSS 355



 Score =  177 bits (450), Expect = 2e-44
 Identities = 82/194 (42%), Positives = 112/194 (57%), Gaps = 1/194 (0%)
 Frame = +2

Query: 71  EQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRN 250
           E+     +C  GNG++YRGT S T  G  CQ W S +PHR   +P   P+ GL  NYCRN
Sbjct: 95  EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154

Query: 251 PDAD-KSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKR 427
           PD D + PWCYTTDP  R++YC++ +C                       E+CM  +G+ 
Sbjct: 155 PDNDPQGPWCYTTDPEKRYDYCDILEC----------------------EEECMHCSGEN 192

Query: 428 YRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNP 607
           Y GK + T++G+ CQ W +Q PH H  + P   P   L+KNYCRNPD +   PWC+TT+P
Sbjct: 193 YDGKISKTMSGLECQAWDSQSPHAHG-YIPSKFPNKNLKKNYCRNPDRELR-PWCFTTDP 250

Query: 608 QKLFDYCDVPQCET 649
            K ++ CD+P+C T
Sbjct: 251 NKRWELCDIPRCTT 264



 Score =  118 bits (296), Expect = 1e-26
 Identities = 48/96 (50%), Positives = 63/96 (65%)
 Frame = +2

Query: 401 DCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDN 580
           +C  GNGK YRG  + T  G+ CQ+W++  PHR   F+P T+P  GLE+NYCRNPD D  
Sbjct: 102 ECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPR-FSPATHPSEGLEENYCRNPDNDPQ 160

Query: 581 GPWCYTTNPQKLFDYCDVPQCETSSFDCGKPKMEPK 688
           GPWCYTT+P+K +DYCD+ +CE     C     + K
Sbjct: 161 GPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGK 196


>ref|NP_005568.1| lipoprotein, Lp(a) [Homo sapiens]
          Length = 4548

 Score =  730 bits (1885), Expect = 0.0
 Identities = 338/479 (70%), Positives = 381/479 (79%), Gaps = 15/479 (3%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAPV--------------PPEQTPVAQDCYRGNGESYRGTSST 139
            YC +  C  S T +  L+ P               P EQTPV + CY GNG+SYRGT ST
Sbjct: 4081 YCNLTQC--SETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHGNGQSYRGTFST 4138

Query: 140  TITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNL 319
            T+TGR CQSW SMTPHRH++TP N+PN GLTMNYCRNPDAD  PWC+T DP +RWEYCNL
Sbjct: 4139 TVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADTGPWCFTMDPSIRWEYCNL 4198

Query: 320  KKCSETEQQVTNFPAIVQVPSVEDLSE-DCMFGNGKRYRGKRATTVAGVPCQEWAAQEPH 496
             +CS+TE  V   P ++QVPS+   SE DCMFGNGK YRGK+ATTV G PCQEWAAQEPH
Sbjct: 4199 TRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQEWAAQEPH 4258

Query: 497  RHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETSSFDCGKPK 676
            RHS F P TN  AGLEKNYCRNPDGD NGPWCYT NP+KLFDYCD+P C +SSFDCGKP+
Sbjct: 4259 RHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPLCASSSFDCGKPQ 4318

Query: 677  MEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSSPS 856
            +EPKKCP  +VGGCV+ PHSWPWQ+SLR R+G HFCGGTLISPEWVLTA HCL+KSS PS
Sbjct: 4319 VEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKKSSRPS 4378

Query: 857  SYKVILGAHEEHHLGEGVQEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLPTPNY 1036
            SYKVILGAH+E +L   VQEI+VS+LF EP+ ADIALLKLS PAVITDKV+PACLP+P+Y
Sbjct: 4379 SYKVILGAHQEVNLESHVQEIEVSRLFLEPTQADIALLKLSRPAVITDKVMPACLPSPDY 4438

Query: 1037 VVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAGHLAG 1216
            +V  RT CYITGWGET+GT+G GLLKEA+L VIEN+VCN Y+Y         +CA HLA 
Sbjct: 4439 MVTARTECYITGWGETQGTFGTGLLKEAQLLVIENEVCNHYKY---------ICAEHLAR 4489

Query: 1217 GIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIMRRN 1393
            G DSCQGDSGGPLVCFEKDKYILQGVTSWGLGCA PNKPGVY RV RFVTWIE +MR N
Sbjct: 4490 GTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMRNN 4548



 Score =  266 bits (679), Expect = 4e-71
 Identities = 122/213 (57%), Positives = 144/213 (67%), Gaps = 11/213 (5%)
 Frame = +2

Query: 38   STEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFP 217
            STE      PPE++PV QDCY G+G SYRG SSTT+TGR CQSW SM PH H++TP N+P
Sbjct: 3991 STEAPSEQAPPEKSPVVQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYP 4050

Query: 218  NAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLS 397
            NAGLT NYCRNPD+ K PWCYTTDP VRWEYCNL +CSETE  V   P +V VPS+E  S
Sbjct: 4051 NAGLTENYCRNPDSGKQPWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHS 4110

Query: 398  E-----------DCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLE 544
            E            C  GNG+ YRG  +TTV G  CQ W++  PHRH   TPE  P  GL 
Sbjct: 4111 EAAPTEQTPVVRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQ-RTPENYPNDGLT 4169

Query: 545  KNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             NYCRNPD  D GPWC+T +P   ++YC++ +C
Sbjct: 4170 MNYCRNPDA-DTGPWCFTMDPSIRWEYCNLTRC 4201



 Score =  248 bits (634), Expect = 7e-66
 Identities = 122/228 (53%), Positives = 142/228 (62%), Gaps = 12/228 (5%)
 Frame = +2

Query: 38   STEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFP 217
            STE      P E +   QDCYRG+G+SYRGT STTITGR CQSW SMTPH H + P  +P
Sbjct: 3877 STELPSEEAPTENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYP 3936

Query: 218  NAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLS 397
            NAGLT NYCRNPDA+  PWCYT DP VRWEYCNL +C  TE  V   P +  VPS E  S
Sbjct: 3937 NAGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPS 3996

Query: 398  E-----------DCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLE 544
            E           DC  G+G+ YRG  +TTV G  CQ W++  PH H   TPE  P AGL 
Sbjct: 3997 EQAPPEKSPVVQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQ-RTPENYPNAGLT 4055

Query: 545  KNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC-ETSSFDCGKPKMEP 685
            +NYCRNPD     PWCYTT+P   ++YC++ QC ET S     P + P
Sbjct: 4056 ENYCRNPDSGKQ-PWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVP 4102



 Score =  241 bits (615), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 3177 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 3236

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 3237 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 3296

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 3297 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 3356

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 3357 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPD-PVAAPYCYTRDPSVRWEYCNLTQC 3411



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 3063 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 3122

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 3123 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 3182

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 3183 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 3242

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 3243 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 3297



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 2949 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 3008

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 3009 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 3068

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 3069 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 3128

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 3129 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 3183



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 2835 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 2894

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 2895 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 2954

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 2955 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 3014

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 3015 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 3069



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 2721 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 2780

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 2781 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 2840

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 2841 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 2900

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 2901 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 2955



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 2607 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 2666

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 2667 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 2726

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 2727 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 2786

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 2787 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 2841



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 2493 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 2552

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 2553 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 2612

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 2613 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 2672

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 2673 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 2727



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 2379 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 2438

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 2439 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 2498

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 2499 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 2558

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 2559 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 2613



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 2265 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 2324

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 2325 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 2384

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 2385 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 2444

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 2445 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 2499



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 2151 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 2210

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 2211 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 2270

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 2271 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 2330

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 2331 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 2385



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 2037 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 2096

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 2097 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 2156

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 2157 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 2216

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 2217 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 2271



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 1923 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 1982

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 1983 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 2042

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 2043 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 2102

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 2103 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 2157



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 1809 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 1868

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 1869 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 1928

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 1929 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 1988

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 1989 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 2043



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 1695 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 1754

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 1755 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 1814

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 1815 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 1874

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 1875 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 1929



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 1581 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 1640

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 1641 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 1700

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 1701 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 1760

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 1761 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 1815



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 1467 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 1526

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 1527 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 1586

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 1587 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 1646

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 1647 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 1701



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 1353 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 1412

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 1413 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 1472

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 1473 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 1532

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 1533 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 1587



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 1239 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 1298

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 1299 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 1358

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 1359 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 1418

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 1419 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 1473



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 1125 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 1184

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 1185 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 1244

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 1245 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 1304

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 1305 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 1359



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 1011 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 1070

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 1071 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 1130

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 1131 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 1190

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 1191 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 1245



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 897  YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 956

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 957  TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 1016

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 1017 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 1076

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 1077 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 1131



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 783  YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 842

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 843  TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 902

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 903  CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 962

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 963  AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 1017



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 669  YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 728

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 729  TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 788

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 789  CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 848

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 849  AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 903



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 555  YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 614

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 615  TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 674

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 675  CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 734

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 735  AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 789



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 441  YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 500

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 501  TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 560

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 561  CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 620

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 621  AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 675



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 327  YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 386

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 387  TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 446

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 447  CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 506

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 507  AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 561



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2   YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
           YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 213 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 272

Query: 146 TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
           TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 273 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 332

Query: 326 CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
           CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 333 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 392

Query: 473 EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
            W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 393 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 447



 Score =  241 bits (614), Expect = 1e-63
 Identities = 118/237 (49%), Positives = 144/237 (60%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2   YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
           YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 99  YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 158

Query: 146 TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
           TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPDA  +P+CYT DP VRWEYCNL +
Sbjct: 159 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQ 218

Query: 326 CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
           CS+ E      P +  VPS+E  SE           +C  GNG+ YRG  +TTV G  CQ
Sbjct: 219 CSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQ 278

Query: 473 EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
            W++  PH HS  TPE  P AGL  NYCRNPD     P+CYT +P   ++YC++ QC
Sbjct: 279 AWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQC 333



 Score =  239 bits (611), Expect = 3e-63
 Identities = 117/247 (47%), Positives = 145/247 (58%), Gaps = 23/247 (9%)
 Frame = +2

Query: 2    YCKIPSCGSS---------TTSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SYRGT STT+
Sbjct: 3291 YCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTV 3350

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL MNYCRNPD   +P+CYT DP VRWEYCNL +
Sbjct: 3351 TGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVAAPYCYTRDPSVRWEYCNLTQ 3410

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P I  +PS+E  SE           +C  GNG+ Y+G    TV G  CQ
Sbjct: 3411 CSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQSYQGTYFITVTGRTCQ 3470

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETS 652
             W++  PH HS  TP   P AGL KNYCRNPD     PWCYTT+P   ++YC++ +C  +
Sbjct: 3471 AWSSMTPHSHS-RTPAYYPNAGLIKNYCRNPD-PVAAPWCYTTDPSVRWEYCNLTRCSDA 3528

Query: 653  SFDCGKP 673
             +    P
Sbjct: 3529 EWTAFVP 3535



 Score =  239 bits (610), Expect = 4e-63
 Identities = 113/237 (47%), Positives = 142/237 (59%), Gaps = 23/237 (9%)
 Frame = +2

Query: 2    YCKIPSCGSST---------TSTEYLDAP---VPPEQTPVAQDCYRGNGESYRGTSSTTI 145
            YC +  C  +          T    L+AP    P EQ P  Q+CY GNG+SY+GT   T+
Sbjct: 3405 YCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQSYQGTYFITV 3464

Query: 146  TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 325
            TGR CQ+W SMTPH H +TP  +PNAGL  NYCRNPD   +PWCYTTDP VRWEYCNL +
Sbjct: 3465 TGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVAAPWCYTTDPSVRWEYCNLTR 3524

Query: 326  CSETEQQVTNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQ 472
            CS+ E      P ++  PS+E   E           DC +  G+ YRG  +TTV G  CQ
Sbjct: 3525 CSDAEWTAFVPPNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQ 3584

Query: 473  EWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             W++  PH+HS  TPE  P AGL +NYCRNPD +   PWCYT +P   ++YC++ QC
Sbjct: 3585 AWSSMTPHQHS-RTPENYPNAGLTRNYCRNPDAEIR-PWCYTMDPSVRWEYCNLTQC 3639



 Score =  237 bits (605), Expect = 2e-62
 Identities = 110/229 (48%), Positives = 140/229 (61%), Gaps = 15/229 (6%)
 Frame = +2

Query: 2    YCKIPSC----GSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSW 169
            YC +  C     S   ++  +    P EQ+P  QDCY G+G+SYRG+ STT+TGR CQSW
Sbjct: 3747 YCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSW 3806

Query: 170  VSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQV 349
             SMTPH H++T   +PN GLT NYCRNPDA+  PWCYT DP VRWEYCNL +C   E  +
Sbjct: 3807 SSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNLTQCPVMESTL 3866

Query: 350  TNFPAIVQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVPCQEWAAQEPH 496
               P +V VPS E  SE           DC  G+G+ YRG  +TT+ G  CQ W++  PH
Sbjct: 3867 LTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPH 3926

Query: 497  RHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
             H    P   P AGL +NYCRNPD +   PWCYT +P   ++YC++ +C
Sbjct: 3927 WHRRI-PLYYPNAGLTRNYCRNPDAEIR-PWCYTMDPSVRWEYCNLTRC 3973



 Score =  237 bits (605), Expect = 2e-62
 Identities = 111/203 (54%), Positives = 136/203 (66%), Gaps = 11/203 (5%)
 Frame = +2

Query: 68  PEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCR 247
           PEQ+ V QDCY G+G+SYRGT STT+TGR CQ+W SMTPH+H +T  N+PNAGL MNYCR
Sbjct: 19  PEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCR 78

Query: 248 NPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSE--------- 400
           NPDA  +P+CYT DP VRWEYCNL +CS+ E      P +  VPS+E  SE         
Sbjct: 79  NPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138

Query: 401 --DCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGD 574
             +C  GNG+ YRG  +TTV G  CQ W++  PH HS  TPE  P AGL  NYCRNPD  
Sbjct: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA- 196

Query: 575 DNGPWCYTTNPQKLFDYCDVPQC 643
              P+CYT +P   ++YC++ QC
Sbjct: 197 VAAPYCYTRDPGVRWEYCNLTQC 219



 Score =  236 bits (602), Expect = 4e-62
 Identities = 109/205 (53%), Positives = 136/205 (66%), Gaps = 3/205 (1%)
 Frame = +2

Query: 38   STEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFP 217
            STE      P EQ+P  QDCY G+G+SYRG+ STT+TGR CQSW SMTPH H++T   +P
Sbjct: 3657 STEASSEEAPTEQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYP 3716

Query: 218  NAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQV--TNFPAIVQVPSVED 391
            N GLT NYCRNPDA+ SPWCYT DP VRWEYCNL +C  TE  V  T+     Q P+ + 
Sbjct: 3717 NGGLTRNYCRNPDAEISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQS 3776

Query: 392  LS-EDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPD 568
             + +DC  G+G+ YRG  +TTV G  CQ W++  PH H   T E  P  GL +NYCRNPD
Sbjct: 3777 PTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQ-RTTEYYPNGGLTRNYCRNPD 3835

Query: 569  GDDNGPWCYTTNPQKLFDYCDVPQC 643
             +   PWCYT +P   ++YC++ QC
Sbjct: 3836 AEIR-PWCYTMDPSVRWEYCNLTQC 3859



 Score =  235 bits (600), Expect = 6e-62
 Identities = 109/202 (53%), Positives = 132/202 (65%), Gaps = 11/202 (5%)
 Frame = +2

Query: 71   EQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRN 250
            E+TP  QDCY   G+SYRGT STT+TGR CQ+W SMTPH+H +TP N+PNAGLT NYCRN
Sbjct: 3554 EETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRN 3613

Query: 251  PDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSE---------- 400
            PDA+  PWCYT DP VRWEYCNL +C  TE  V     +V  PS E  SE          
Sbjct: 3614 PDAEIRPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGV 3673

Query: 401  -DCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDD 577
             DC  G+G+ YRG  +TTV G  CQ W++  PH H   T E  P  GL +NYCRNPD + 
Sbjct: 3674 QDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQ-RTTEYYPNGGLTRNYCRNPDAEI 3732

Query: 578  NGPWCYTTNPQKLFDYCDVPQC 643
            + PWCYT +P   ++YC++ QC
Sbjct: 3733 S-PWCYTMDPNVRWEYCNLTQC 3753


>ref|XP_946885.1| PREDICTED: similar to Apolipoprotein(a) precursor (Apo(a)) (Lp(a))
            [Homo sapiens]
          Length = 440

 Score =  615 bits (1587), Expect = e-176
 Identities = 281/378 (74%), Positives = 315/378 (83%), Gaps = 1/378 (0%)
 Frame = +2

Query: 233  MNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSE-DCM 409
            MNYCRNPDAD  PWC+T DP +RWEYCNL +CS+TE  V   P ++QVPS+   SE DCM
Sbjct: 1    MNYCRNPDADTGPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCM 60

Query: 410  FGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPW 589
            FGNGK YRGK+ATTV G PCQEWAAQEPHRHS F P TN  AGLEKNYCRNPDGD NGPW
Sbjct: 61   FGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPW 120

Query: 590  CYTTNPQKLFDYCDVPQCETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISLRRRY 769
            CYT NP+KLFDYCD+P C +SSFDCGKP++EPKKCP  +VGGCV+ PHSWPWQ+SLR R+
Sbjct: 121  CYTMNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRF 180

Query: 770  GGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLFKEPS 949
            G HFCGGTLISPEWVLTA HCL+KSS PSSYKVILGAH+E +L   VQEI+VS+LF EP+
Sbjct: 181  GKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPT 240

Query: 950  GADIALLKLSSPAVITDKVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLKEARLP 1129
             ADIALLKLS PAVITDKV+PACLP+P+Y+V  RT CYITGWGET+GT+G GLLKEA+L 
Sbjct: 241  QADIALLKLSRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLL 300

Query: 1130 VIENKVCNRYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGL 1309
            VIEN+VCN Y+Y         +CA HLA G DSCQGDSGGPLVCFEKDKYILQGVTSWGL
Sbjct: 301  VIENEVCNHYKY---------ICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL 351

Query: 1310 GCALPNKPGVYVRVXRFV 1363
            GCA PNKPGVY RV R +
Sbjct: 352  GCARPNKPGVYARVSRMI 369



 Score =  105 bits (262), Expect = 9e-23
 Identities = 50/116 (43%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
 Frame = +2

Query: 2   YCKIPSCGSS--TTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVS 175
           YC +  C  +  T         VP    P  QDC  GNG+ YRG  +TT+TG  CQ W +
Sbjct: 26  YCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQEWAA 85

Query: 176 MTPHRHEK-TPGNFPNAGLTMNYCRNPDAD-KSPWCYTTDPRVRWEYCNLKKCSET 337
             PHRH    PG    AGL  NYCRNPD D   PWCYT +PR  ++YC++  C+ +
Sbjct: 86  QEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPLCASS 141


>ref|XP_931416.1| PREDICTED: similar to Apolipoprotein(a) precursor (Apo(a)) (Lp(a))
            [Homo sapiens]
          Length = 440

 Score =  615 bits (1587), Expect = e-176
 Identities = 281/378 (74%), Positives = 315/378 (83%), Gaps = 1/378 (0%)
 Frame = +2

Query: 233  MNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSE-DCM 409
            MNYCRNPDAD  PWC+T DP +RWEYCNL +CS+TE  V   P ++QVPS+   SE DCM
Sbjct: 1    MNYCRNPDADTGPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCM 60

Query: 410  FGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPW 589
            FGNGK YRGK+ATTV G PCQEWAAQEPHRHS F P TN  AGLEKNYCRNPDGD NGPW
Sbjct: 61   FGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPW 120

Query: 590  CYTTNPQKLFDYCDVPQCETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISLRRRY 769
            CYT NP+KLFDYCD+P C +SSFDCGKP++EPKKCP  +VGGCV+ PHSWPWQ+SLR R+
Sbjct: 121  CYTMNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRF 180

Query: 770  GGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLFKEPS 949
            G HFCGGTLISPEWVLTA HCL+KSS PSSYKVILGAH+E +L   VQEI+VS+LF EP+
Sbjct: 181  GKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPT 240

Query: 950  GADIALLKLSSPAVITDKVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLKEARLP 1129
             ADIALLKLS PAVITDKV+PACLP+P+Y+V  RT CYITGWGET+GT+G GLLKEA+L 
Sbjct: 241  QADIALLKLSRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLL 300

Query: 1130 VIENKVCNRYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGL 1309
            VIEN+VCN Y+Y         +CA HLA G DSCQGDSGGPLVCFEKDKYILQGVTSWGL
Sbjct: 301  VIENEVCNHYKY---------ICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL 351

Query: 1310 GCALPNKPGVYVRVXRFV 1363
            GCA PNKPGVY RV R +
Sbjct: 352  GCARPNKPGVYARVSRMI 369



 Score =  105 bits (262), Expect = 9e-23
 Identities = 50/116 (43%), Positives = 63/116 (54%), Gaps = 4/116 (3%)
 Frame = +2

Query: 2   YCKIPSCGSS--TTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVS 175
           YC +  C  +  T         VP    P  QDC  GNG+ YRG  +TT+TG  CQ W +
Sbjct: 26  YCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQEWAA 85

Query: 176 MTPHRHEK-TPGNFPNAGLTMNYCRNPDAD-KSPWCYTTDPRVRWEYCNLKKCSET 337
             PHRH    PG    AGL  NYCRNPD D   PWCYT +PR  ++YC++  C+ +
Sbjct: 86  QEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPLCASS 141


>ref|NP_066278.2| macrophage stimulating 1 (hepatocyte growth factor-like) [Homo
            sapiens]
          Length = 711

 Score =  345 bits (885), Expect = 5e-95
 Identities = 181/481 (37%), Positives = 255/481 (53%), Gaps = 19/481 (3%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
            +C +P CGS             P Q      C+RG GE YRGT++TT  G  CQ W +  
Sbjct: 262  FCDLPRCGSEAQ----------PRQEATTVSCFRGKGEGYRGTANTTTAGVPCQRWDAQI 311

Query: 182  PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYC-NLKKCSETEQQVTNF 358
            PH+H  TP  +    L  N+CRNPD  ++PWC+T  P +R  +C  +++C++  +     
Sbjct: 312  PHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFTLRPGMRAAFCYQIRRCTDDVR----- 366

Query: 359  PAIVQVPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAG 538
                         +DC  G G++YRG  + T  GV CQ W+A+ PH+   FT  + P A 
Sbjct: 367  ------------PQDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQ-FTFTSEPHAQ 413

Query: 539  LEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC-------------ETSSFDCGK--P 673
            LE+N+CRNPDGD +GPWCYT +P+  FDYC + +C             +     CGK   
Sbjct: 414  LEENFCRNPDGDSHGPWCYTMDPRTPFDYCALRRCADDQPPSILDPPDQVQFEKCGKRVD 473

Query: 674  KMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSSP 853
            +++ ++   RVVGG    P + PW +SLR R G HFCGG+L+  +W+LTA+ C      P
Sbjct: 474  RLDQRRSKLRVVGG---HPGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMP 530

Query: 854  -SSYKVILGA--HEEHHLGEGVQEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLP 1024
             + Y+V LG       H    +Q + V+K+   PSG+ + LLKL     +  +V   CLP
Sbjct: 531  LTGYEVWLGTLFQNPQHGEPSLQRVPVAKMVCGPSGSQLVLLKLERSVTLNQRVALICLP 590

Query: 1025 TPNYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAG 1204
               YVV   T C I GWGETKGT    +L  A L VI N+ CN      G+V  +E+C  
Sbjct: 591  PEWYVVPPGTKCEIAGWGETKGTGNDTVLNVALLNVISNQECNIKH--RGRVRESEMCTE 648

Query: 1205 HLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIM 1384
             L   + +C+GD GGPL CF  + ++L+G+      CA    P V+ RV  FV WI ++M
Sbjct: 649  GLLAPVGACEGDYGGPLACFTHNCWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVM 708

Query: 1385 R 1387
            R
Sbjct: 709  R 709



 Score =  171 bits (432), Expect = 2e-42
 Identities = 81/178 (45%), Positives = 99/178 (55%)
 Frame = +2

Query: 95  CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPW 274
           C   NGE YRG    T +GR+CQ W    PH+H   PG F + GL  NYCRNPD  + PW
Sbjct: 191 CVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSERPW 250

Query: 275 CYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRGKRATTV 454
           CYTTDP++  E+C+L +C    Q           P  E  +  C  G G+ YRG   TT 
Sbjct: 251 CYTTDPQIEREFCDLPRCGSEAQ-----------PRQEATTVSCFRGKGEGYRGTANTTT 299

Query: 455 AGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 628
           AGVPCQ W AQ PH+H  FTPE      L +N+CRNPDG +  PWC+T  P     +C
Sbjct: 300 AGVPCQRWDAQIPHQHR-FTPEKYACKDLRENFCRNPDGSE-APWCFTLRPGMRAAFC 355



 Score =  159 bits (401), Expect = 7e-39
 Identities = 89/234 (38%), Positives = 116/234 (49%), Gaps = 9/234 (3%)
 Frame = +2

Query: 95  CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADK-SP 271
           C   NG  YRGT +TT+ G  CQ+W    P+ H+ TP      GL  N+CRNPD D   P
Sbjct: 110 CIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTP--TLRNGLEENFCRNPDGDPGGP 167

Query: 272 WCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRGKRATT 451
           WCYTTDP VR++ C +K C E                       C++ NG+ YRG    T
Sbjct: 168 WCYTTDPAVRFQSCGIKSCREAA---------------------CVWCNGEEYRGAVDRT 206

Query: 452 VAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCD 631
            +G  CQ W  Q PH+H  F P      GL+ NYCRNPDG +  PWCYTT+PQ   ++CD
Sbjct: 207 ESGRECQRWDLQHPHQHP-FEPGKFLDQGLDDNYCRNPDGSER-PWCYTTDPQIEREFCD 264

Query: 632 VPQC--------ETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISLRRRY 769
           +P+C        E ++  C + K E  +  A      V     W  QI  + R+
Sbjct: 265 LPRCGSEAQPRQEATTVSCFRGKGEGYRGTANTTTAGVPC-QRWDAQIPHQHRF 317



 Score = 97.4 bits (241), Expect = 3e-20
 Identities = 43/90 (47%), Positives = 56/90 (62%)
 Frame = +2

Query: 386 EDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNP 565
           +D    C+  NG  YRG  ATTV G+PCQ W+ + P+ H  +TP    R GLE+N+CRNP
Sbjct: 104 KDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHK-YTPTL--RNGLEENFCRNP 160

Query: 566 DGDDNGPWCYTTNPQKLFDYCDVPQCETSS 655
           DGD  GPWCYTT+P   F  C +  C  ++
Sbjct: 161 DGDPGGPWCYTTDPAVRFQSCGIKSCREAA 190


>ref|NP_001010932.1| hepatocyte growth factor isoform 3 precursor [Homo sapiens]
          Length = 723

 Score =  323 bits (827), Expect = 3e-88
 Identities = 185/479 (38%), Positives = 255/479 (53%), Gaps = 18/479 (3%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
            YC I +C  +T +    D  VP E T    +C +G GE YRGT +T   G  CQ W S  
Sbjct: 277  YCAIKTCADNTMN----DTDVPLETT----ECIQGQGEGYRGTVNTIWNGIPCQRWDSQY 328

Query: 182  PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFP 361
            PH H+ TP NF    L  NYCRNPD  +SPWC+TTDP +R  YC+               
Sbjct: 329  PHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVGYCS--------------- 373

Query: 362  AIVQVPSVE-DLSEDCMFGNGKRYRGKRATTVAGVPCQEWAA--QEPHRHSIFTPETNPR 532
               Q+P+ +    +DC  GNGK Y G  + T +G+ C  W    ++ HRH  + P+ +  
Sbjct: 374  ---QIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASK- 429

Query: 533  AGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETSS-----------FDCGKPKM 679
              L +NYCRNPD D +GPWCYT NP   +DYC + +CE  +             C K K 
Sbjct: 430  --LNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTKQ 487

Query: 680  EPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSSPSS 859
                   RVV G +    +  W +SLR R   H CGG+LI   WVLTA+ C   S     
Sbjct: 488  ------LRVVNG-IPTRTNIGWMVSLRYR-NKHICGGSLIKESWVLTARQCFP-SRDLKD 538

Query: 860  YKVILGAHEEHHLGEGV--QEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLPTPN 1033
            Y+  LG H+ H  G+    Q ++VS+L   P G+D+ L+KL+ PAV+ D V    LP   
Sbjct: 539  YEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLPNYG 598

Query: 1034 YVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNE--LCAGH 1207
              + ++T+C + GWG T      GLL+ A L ++ N+ C+++    GKV+ NE  +CAG 
Sbjct: 599  CTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHR--GKVTLNESEICAGA 656

Query: 1208 LAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIM 1384
               G   C+GD GGPLVC +    ++ GV   G GCA+PN+PG++VRV  +  WI +I+
Sbjct: 657  EKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 715



 Score =  182 bits (461), Expect = 8e-46
 Identities = 88/214 (41%), Positives = 113/214 (52%), Gaps = 1/214 (0%)
 Frame = +2

Query: 14  PSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRH 193
           P C +S     Y    +P         C   NGESYRG    T +G+ CQ W   TPHRH
Sbjct: 182 PWCFTSNPEVRYEVCDIPQCSEVECMTC---NGESYRGLMDHTESGKICQRWDHQTPHRH 238

Query: 194 EKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQ 373
           +  P  +P+ G   NYCRNPD    PWCYT DP  RWEYC +K C++     T+ P    
Sbjct: 239 KFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPL--- 295

Query: 374 VPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNY 553
                  + +C+ G G+ YRG   T   G+PCQ W +Q PH H + TPE      L +NY
Sbjct: 296 ------ETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDM-TPENFKCKDLRENY 348

Query: 554 CRNPDGDDNGPWCYTTNPQKLFDYC-DVPQCETS 652
           CRNPDG ++ PWC+TT+P     YC  +P C+ S
Sbjct: 349 CRNPDGSES-PWCFTTDPNIRVGYCSQIPNCDMS 381



 Score =  160 bits (404), Expect = 3e-39
 Identities = 81/209 (38%), Positives = 108/209 (51%), Gaps = 1/209 (0%)
 Frame = +2

Query: 71  EQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRN 250
           E     ++C  G G SY+GT S T +G KCQ W SM PH H     ++    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRN 174

Query: 251 PDADK-SPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKR 427
           P  ++  PWC+T++P VR+E C++ +CSE E                     CM  NG+ 
Sbjct: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE---------------------CMTCNGES 213

Query: 428 YRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNP 607
           YRG    T +G  CQ W  Q PHRH  F PE  P  G + NYCRNPDG    PWCYT +P
Sbjct: 214 YRGLMDHTESGKICQRWDHQTPHRHK-FLPERYPDKGFDDNYCRNPDGQPR-PWCYTLDP 271

Query: 608 QKLFDYCDVPQCETSSFDCGKPKMEPKKC 694
              ++YC +  C  ++ +     +E  +C
Sbjct: 272 HTRWEYCAIKTCADNTMNDTDVPLETTEC 300


>ref|NP_000592.3| hepatocyte growth factor isoform 1 preproprotein [Homo sapiens]
          Length = 728

 Score =  323 bits (827), Expect = 3e-88
 Identities = 185/479 (38%), Positives = 255/479 (53%), Gaps = 18/479 (3%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
            YC I +C  +T +    D  VP E T    +C +G GE YRGT +T   G  CQ W S  
Sbjct: 282  YCAIKTCADNTMN----DTDVPLETT----ECIQGQGEGYRGTVNTIWNGIPCQRWDSQY 333

Query: 182  PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFP 361
            PH H+ TP NF    L  NYCRNPD  +SPWC+TTDP +R  YC+               
Sbjct: 334  PHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVGYCS--------------- 378

Query: 362  AIVQVPSVE-DLSEDCMFGNGKRYRGKRATTVAGVPCQEWAA--QEPHRHSIFTPETNPR 532
               Q+P+ +    +DC  GNGK Y G  + T +G+ C  W    ++ HRH  + P+ +  
Sbjct: 379  ---QIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASK- 434

Query: 533  AGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETSS-----------FDCGKPKM 679
              L +NYCRNPD D +GPWCYT NP   +DYC + +CE  +             C K K 
Sbjct: 435  --LNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTKQ 492

Query: 680  EPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSSPSS 859
                   RVV G +    +  W +SLR R   H CGG+LI   WVLTA+ C   S     
Sbjct: 493  ------LRVVNG-IPTRTNIGWMVSLRYR-NKHICGGSLIKESWVLTARQCFP-SRDLKD 543

Query: 860  YKVILGAHEEHHLGEGV--QEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLPTPN 1033
            Y+  LG H+ H  G+    Q ++VS+L   P G+D+ L+KL+ PAV+ D V    LP   
Sbjct: 544  YEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLPNYG 603

Query: 1034 YVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNE--LCAGH 1207
              + ++T+C + GWG T      GLL+ A L ++ N+ C+++    GKV+ NE  +CAG 
Sbjct: 604  CTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHR--GKVTLNESEICAGA 661

Query: 1208 LAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIM 1384
               G   C+GD GGPLVC +    ++ GV   G GCA+PN+PG++VRV  +  WI +I+
Sbjct: 662  EKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 720



 Score =  182 bits (461), Expect = 8e-46
 Identities = 88/214 (41%), Positives = 113/214 (52%), Gaps = 1/214 (0%)
 Frame = +2

Query: 14  PSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRH 193
           P C +S     Y    +P         C   NGESYRG    T +G+ CQ W   TPHRH
Sbjct: 187 PWCFTSNPEVRYEVCDIPQCSEVECMTC---NGESYRGLMDHTESGKICQRWDHQTPHRH 243

Query: 194 EKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQ 373
           +  P  +P+ G   NYCRNPD    PWCYT DP  RWEYC +K C++     T+ P    
Sbjct: 244 KFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPL--- 300

Query: 374 VPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNY 553
                  + +C+ G G+ YRG   T   G+PCQ W +Q PH H + TPE      L +NY
Sbjct: 301 ------ETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDM-TPENFKCKDLRENY 353

Query: 554 CRNPDGDDNGPWCYTTNPQKLFDYC-DVPQCETS 652
           CRNPDG ++ PWC+TT+P     YC  +P C+ S
Sbjct: 354 CRNPDGSES-PWCFTTDPNIRVGYCSQIPNCDMS 386



 Score =  167 bits (423), Expect = 2e-41
 Identities = 82/209 (39%), Positives = 109/209 (52%), Gaps = 1/209 (0%)
 Frame = +2

Query: 71  EQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRN 250
           E     ++C  G G SY+GT S T +G KCQ W SM PH H   P ++    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 251 PDADK-SPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKR 427
           P  ++  PWC+T++P VR+E C++ +CSE E                     CM  NG+ 
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE---------------------CMTCNGES 218

Query: 428 YRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNP 607
           YRG    T +G  CQ W  Q PHRH  F PE  P  G + NYCRNPDG    PWCYT +P
Sbjct: 219 YRGLMDHTESGKICQRWDHQTPHRHK-FLPERYPDKGFDDNYCRNPDGQPR-PWCYTLDP 276

Query: 608 QKLFDYCDVPQCETSSFDCGKPKMEPKKC 694
              ++YC +  C  ++ +     +E  +C
Sbjct: 277 HTRWEYCAIKTCADNTMNDTDVPLETTEC 305


>ref|NP_127509.1| plasminogen activator, tissue type isoform 3 precursor [Homo sapiens]
          Length = 516

 Score =  246 bits (629), Expect = 3e-65
 Identities = 170/464 (36%), Positives = 225/464 (48%), Gaps = 33/464 (7%)
 Frame = +2

Query: 95   CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNA---GL-TMNYCRNPDAD 262
            CY   G SYRGT ST  +G +C +W S +    +   G  P+A   GL   NYCRNPD D
Sbjct: 81   CYEDQGISYRGTWSTAESGAECTNWNS-SALAQKPYSGRRPDAIRLGLGNHNYCRNPDRD 139

Query: 263  KSPWCYTTDP-RVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRGK 439
              PWCY     +   E+C+   CSE                    + DC FGNG  YRG 
Sbjct: 140  SKPWCYVFKAGKYSSEFCSTPACSEG-------------------NSDCYFGNGSAYRGT 180

Query: 440  RATTVAGVPCQEWAAQEPHRHSIFTPETNPRA---GLEK-NYCRNPDGDDNGPWCYTTNP 607
             + T +G  C  W +       ++T + NP A   GL K NYCRNPDGD   PWC+    
Sbjct: 181  HSLTESGASCLPWNSMILIG-KVYTAQ-NPSAQALGLGKHNYCRNPDGDAK-PWCHVLKN 237

Query: 608  QKL-FDYCDVPQCETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISL----RRRYG 772
            ++L ++YCDVP C T    CG  +    +   R+ GG  +   S PWQ ++    RR  G
Sbjct: 238  RRLTWEYCDVPSCST----CGLRQYSQPQF--RIKGGLFADIASHPWQAAIFAKHRRSPG 291

Query: 773  GHF-CGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLF---- 937
              F CGG LIS  W+L+A HC ++   P    VILG       GE  Q+ +V K      
Sbjct: 292  ERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKE 351

Query: 938  --KEPSGADIALLKLSSP----AVITDKVIPACLPTPNYVVADRTACYITGWG--ETKGT 1093
               +    DIALL+L S     A  +  V   CLP  +  + D T C ++G+G  E    
Sbjct: 352  FDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSP 411

Query: 1094 YGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAGHLAGG------IDSCQGDSGGPL 1255
            + +  LKEA + +  +  C     L   V+ N LCAG    G       D+CQGDSGGPL
Sbjct: 412  FYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPL 471

Query: 1256 VCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIMR 1387
            VC    +  L G+ SWGLGC   + PGVY +V  ++ WI + MR
Sbjct: 472  VCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMR 515



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 42/102 (41%), Positives = 52/102 (50%), Gaps = 4/102 (3%)
 Frame = +2

Query: 38  STEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFP 217
           S+E+   P   E      DCY GNG +YRGT S T +G  C  W SM       T  N  
Sbjct: 153 SSEFCSTPACSEGN---SDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPS 209

Query: 218 NAGLTM---NYCRNPDADKSPWCYT-TDPRVRWEYCNLKKCS 331
              L +   NYCRNPD D  PWC+   + R+ WEYC++  CS
Sbjct: 210 AQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCS 251


>ref|NP_000921.1| plasminogen activator, tissue type isoform 1 preproprotein [Homo
            sapiens]
          Length = 562

 Score =  246 bits (629), Expect = 3e-65
 Identities = 170/464 (36%), Positives = 225/464 (48%), Gaps = 33/464 (7%)
 Frame = +2

Query: 95   CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNA---GL-TMNYCRNPDAD 262
            CY   G SYRGT ST  +G +C +W S +    +   G  P+A   GL   NYCRNPD D
Sbjct: 127  CYEDQGISYRGTWSTAESGAECTNWNS-SALAQKPYSGRRPDAIRLGLGNHNYCRNPDRD 185

Query: 263  KSPWCYTTDP-RVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRGK 439
              PWCY     +   E+C+   CSE                    + DC FGNG  YRG 
Sbjct: 186  SKPWCYVFKAGKYSSEFCSTPACSEG-------------------NSDCYFGNGSAYRGT 226

Query: 440  RATTVAGVPCQEWAAQEPHRHSIFTPETNPRA---GLEK-NYCRNPDGDDNGPWCYTTNP 607
             + T +G  C  W +       ++T + NP A   GL K NYCRNPDGD   PWC+    
Sbjct: 227  HSLTESGASCLPWNSMILIG-KVYTAQ-NPSAQALGLGKHNYCRNPDGDAK-PWCHVLKN 283

Query: 608  QKL-FDYCDVPQCETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISL----RRRYG 772
            ++L ++YCDVP C T    CG  +    +   R+ GG  +   S PWQ ++    RR  G
Sbjct: 284  RRLTWEYCDVPSCST----CGLRQYSQPQF--RIKGGLFADIASHPWQAAIFAKHRRSPG 337

Query: 773  GHF-CGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLF---- 937
              F CGG LIS  W+L+A HC ++   P    VILG       GE  Q+ +V K      
Sbjct: 338  ERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKE 397

Query: 938  --KEPSGADIALLKLSSP----AVITDKVIPACLPTPNYVVADRTACYITGWG--ETKGT 1093
               +    DIALL+L S     A  +  V   CLP  +  + D T C ++G+G  E    
Sbjct: 398  FDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSP 457

Query: 1094 YGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAGHLAGG------IDSCQGDSGGPL 1255
            + +  LKEA + +  +  C     L   V+ N LCAG    G       D+CQGDSGGPL
Sbjct: 458  FYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPL 517

Query: 1256 VCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIMR 1387
            VC    +  L G+ SWGLGC   + PGVY +V  ++ WI + MR
Sbjct: 518  VCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMR 561



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 42/102 (41%), Positives = 52/102 (50%), Gaps = 4/102 (3%)
 Frame = +2

Query: 38  STEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFP 217
           S+E+   P   E      DCY GNG +YRGT S T +G  C  W SM       T  N  
Sbjct: 199 SSEFCSTPACSEGN---SDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPS 255

Query: 218 NAGLTM---NYCRNPDADKSPWCYT-TDPRVRWEYCNLKKCS 331
              L +   NYCRNPD D  PWC+   + R+ WEYC++  CS
Sbjct: 256 AQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCS 297


>ref|NP_892028.1| hepsin (transmembrane protease, serine 1) [Homo sapiens]
          Length = 417

 Score =  210 bits (534), Expect = 3e-54
 Identities = 128/332 (38%), Positives = 178/332 (53%), Gaps = 20/332 (6%)
 Frame = +2

Query: 452  VAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCD 631
            VAG+ C+E        HS     T    G    +C      D G   +T    ++   CD
Sbjct: 85   VAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCV-----DEGRLPHTQRLLEVISVCD 139

Query: 632  VPQCETSSF---DCGKPKMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLIS 802
             P+    +    DCG+ K+       R+VGG  +    WPWQ+SLR   G H CGG+L+S
Sbjct: 140  CPRGRFLAAICQDCGRRKLPVD----RIVGGRDTSLGRWPWQVSLRYD-GAHLCGGSLLS 194

Query: 803  PEWVLTAKHCL-EKSSSPSSYKVILGAHEE---HHLGEGVQEIDVSK---LFKEPSGA-- 955
             +WVLTA HC  E++   S ++V  GA  +   H L  GVQ +        F++P+    
Sbjct: 195  GDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEEN 254

Query: 956  --DIALLKLSSPAVITDKVIPACLPTPNYVVADRTACYITGWGETKGTYG--AGLLKEAR 1123
              DIAL+ LSSP  +T+ + P CLP     + D   C +TGWG T+  YG  AG+L+EAR
Sbjct: 255  SNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQEAR 313

Query: 1124 LPVIENKVCNRYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEK----DKYILQG 1291
            +P+I N VCN  ++ G ++ P   CAG+  GGID+CQGDSGGP VC +      ++ L G
Sbjct: 314  VPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCG 373

Query: 1292 VTSWGLGCALPNKPGVYVRVXRFVTWIEEIMR 1387
            + SWG GCAL  KPGVY +V  F  WI + ++
Sbjct: 374  IVSWGTGCALAQKPGVYTKVSDFREWIFQAIK 405


  Database: RefSeqHP
    Posted date:  Aug 2, 2006 12:57 AM
  Number of letters in database: 17,774,539
  Number of sequences in database:  39,411
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,596,646
Number of Sequences: 39411
Number of extensions: 2108248
Number of successful extensions: 10680
Number of sequences better than 1.0e-05: 10
Number of HSP's better than  0.0 without gapping: 6722
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9839
length of database: 17,774,539
effective HSP length: 106
effective length of database: 13,596,973
effective search space used: 4990089091
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)


Search to RefSeqCP
BLASTX 2.2.10 [Oct-19-2004]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20060611C-000407
         (1422 letters)

Database: RefSeqCP 
           33,732 sequences; 19,266,565 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|XP_533468.2| PREDICTED: similar to Plasminogen precursor [Ca...   830   0.0  
Alignment   gi|XP_541884.2| PREDICTED: similar to macrophage stimulating 1 ...   350   3e-96
Alignment   gi|NP_001002964.1| hepatocyte growth factor [Canis familiaris]       322   7e-88
Alignment   gi|XP_539955.2| PREDICTED: similar to Tissue-type plasminogen a...   260   3e-69
Alignment   gi|XP_541697.2| PREDICTED: similar to Serine protease hepsin (T...   205   8e-53
Alignment   gi|XP_535016.2| PREDICTED: similar to hyaluronan binding protei...   201   1e-51
Alignment   gi|XP_853682.1| PREDICTED: similar to Transmembrane protease, s...   200   2e-51
Alignment   gi|XP_850538.1| PREDICTED: hepatocyte growth factor activator i...   200   3e-51
Alignment   gi|XP_861645.1| PREDICTED: hepatocyte growth factor activator i...   200   3e-51
Alignment   gi|NP_001026985.1| HGF activator [Canis familiaris]                  200   3e-51

>ref|XP_533468.2| PREDICTED: similar to Plasminogen precursor [Canis familiaris]
          Length = 812

 Score =  830 bits (2144), Expect = 0.0
 Identities = 383/467 (82%), Positives = 414/467 (88%), Gaps = 3/467 (0%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAP--VPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVS 175
            +C+IPSC SS  +TEYLDAP  VPPEQTPV Q+CY GNG+SYRGTSSTTITGRKCQSW S
Sbjct: 346  HCQIPSCESSPITTEYLDAPASVPPEQTPVVQECYHGNGQSYRGTSSTTITGRKCQSWSS 405

Query: 176  MTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTN 355
            MTPHRHEKTP +FP AGLTMNYCRNPDADKSPWCYTTDP VRWE+CNL+KC + E   TN
Sbjct: 406  MTPHRHEKTPEHFPEAGLTMNYCRNPDADKSPWCYTTDPSVRWEFCNLRKCLDPEASATN 465

Query: 356  FPAIVQVPSVEDLS-EDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPR 532
             PA+ QVPS ++ S  DCMFGNGK YRGK+ATTV G+PCQEWAAQEPHRHSIFTPETNP+
Sbjct: 466  SPAVPQVPSGQEPSASDCMFGNGKGYRGKKATTVMGIPCQEWAAQEPHRHSIFTPETNPQ 525

Query: 533  AGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETSSFDCGKPKMEPKKCPARVVG 712
            AGLEKNYCRNPDGD NGPWCYT N +KLFDYCDVPQC ++SFDCGKP++EPKKCP RVVG
Sbjct: 526  AGLEKNYCRNPDGDVNGPWCYTMNQRKLFDYCDVPQCVSTSFDCGKPQVEPKKCPGRVVG 585

Query: 713  GCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEH 892
            GCV+ PHSWPWQISLR RYG HFCGGTLISPEWVLTA HCLE+SS P+SYKVILGAH+E 
Sbjct: 586  GCVANPHSWPWQISLRTRYGKHFCGGTLISPEWVLTAAHCLERSSRPASYKVILGAHKEV 645

Query: 893  HLGEGVQEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLPTPNYVVADRTACYITG 1072
            +L   VQEI+V KLF EP+ ADIALLKLSSPAVIT KVIPACLP PNYVVADRT CYITG
Sbjct: 646  NLESDVQEIEVYKLFLEPTRADIALLKLSSPAVITSKVIPACLPPPNYVVADRTLCYITG 705

Query: 1073 WGETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGP 1252
            WGET+GTYGAGLLKEA+LPVIENKVCNRYEYL G+V   ELCAG+LAGG DSCQGDSGGP
Sbjct: 706  WGETQGTYGAGLLKEAQLPVIENKVCNRYEYLNGRVKSTELCAGNLAGGTDSCQGDSGGP 765

Query: 1253 LVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIMRRN 1393
            LVCFEKDKYILQGVTSWGLGCA PNKPGVYVRV RFVTWIE IMR N
Sbjct: 766  LVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGIMRNN 812



 Score =  208 bits (530), Expect = 9e-54
 Identities = 95/215 (44%), Positives = 124/215 (57%), Gaps = 1/215 (0%)
 Frame = +2

Query: 2   YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
           +C IP C +            PP   P  Q C +G GESYRG  S T++G  CQ W   T
Sbjct: 256 FCDIPRCTTP-----------PPPSGPTYQ-CLKGRGESYRGKVSVTVSGHTCQHWSEQT 303

Query: 182 PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFP 361
           PH+H +TP NFP   L  NYCRNPD + +PWCYTT+  VRWE+C +  C  +        
Sbjct: 304 PHKHNRTPENFPCKNLDENYCRNPDGETAPWCYTTNSEVRWEHCQIPSCESSPITTEYLD 363

Query: 362 AIVQVPSVE-DLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAG 538
           A   VP  +  + ++C  GNG+ YRG  +TT+ G  CQ W++  PHRH   TPE  P AG
Sbjct: 364 APASVPPEQTPVVQECYHGNGQSYRGTSSTTITGRKCQSWSSMTPHRHE-KTPEHFPEAG 422

Query: 539 LEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
           L  NYCRNPD  D  PWCYTT+P   +++C++ +C
Sbjct: 423 LTMNYCRNPDA-DKSPWCYTTDPSVRWEFCNLRKC 456



 Score =  190 bits (483), Expect = 3e-48
 Identities = 87/217 (40%), Positives = 119/217 (54%)
 Frame = +2

Query: 2   YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
           YC IP C                      ++C   +GE+Y G  S T +G +CQ+W S T
Sbjct: 175 YCNIPEC---------------------EEECMHCSGENYEGKISKTKSGLECQAWNSQT 213

Query: 182 PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFP 361
           PH H   P  FP+  L MNYCRNPD +  PWC+T DP  RWE+C++ +C+          
Sbjct: 214 PHAHGYIPSKFPSKNLKMNYCRNPDGEPRPWCFTMDPNKRWEFCDIPRCTTP-------- 265

Query: 362 AIVQVPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGL 541
                P     +  C+ G G+ YRGK + TV+G  CQ W+ Q PH+H+  TPE  P   L
Sbjct: 266 -----PPPSGPTYQCLKGRGESYRGKVSVTVSGHTCQHWSEQTPHKHN-RTPENFPCKNL 319

Query: 542 EKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETS 652
           ++NYCRNPDG +  PWCYTTN +  +++C +P CE+S
Sbjct: 320 DENYCRNPDG-ETAPWCYTTNSEVRWEHCQIPSCESS 355



 Score =  172 bits (435), Expect = 9e-43
 Identities = 78/187 (41%), Positives = 108/187 (57%), Gaps = 1/187 (0%)
 Frame = +2

Query: 92  DCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKS- 268
           +C  GNG++YRGT + T     CQ W   +PH+   TP   P  GL  NYCRNPD D++ 
Sbjct: 102 ECKTGNGKTYRGTMAKTKNDVACQKWSDNSPHKPNYTPEKHPLEGLEENYCRNPDNDENG 161

Query: 269 PWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRGKRAT 448
           PWCYTT+P VR++YCN+ +C                       E+CM  +G+ Y GK + 
Sbjct: 162 PWCYTTNPDVRFDYCNIPEC----------------------EEECMHCSGENYEGKISK 199

Query: 449 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 628
           T +G+ CQ W +Q PH H  + P   P   L+ NYCRNPDG+   PWC+T +P K +++C
Sbjct: 200 TKSGLECQAWNSQTPHAHG-YIPSKFPSKNLKMNYCRNPDGEPR-PWCFTMDPNKRWEFC 257

Query: 629 DVPQCET 649
           D+P+C T
Sbjct: 258 DIPRCTT 264



 Score =  122 bits (305), Expect = 1e-27
 Identities = 51/96 (53%), Positives = 63/96 (65%)
 Frame = +2

Query: 401 DCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDN 580
           +C  GNGK YRG  A T   V CQ+W+   PH+ + +TPE +P  GLE+NYCRNPD D+N
Sbjct: 102 ECKTGNGKTYRGTMAKTKNDVACQKWSDNSPHKPN-YTPEKHPLEGLEENYCRNPDNDEN 160

Query: 581 GPWCYTTNPQKLFDYCDVPQCETSSFDCGKPKMEPK 688
           GPWCYTTNP   FDYC++P+CE     C     E K
Sbjct: 161 GPWCYTTNPDVRFDYCNIPECEEECMHCSGENYEGK 196


>ref|XP_541884.2| PREDICTED: similar to macrophage stimulating 1 (hepatocyte growth
            factor-like) [Canis familiaris]
          Length = 712

 Score =  350 bits (897), Expect = 3e-96
 Identities = 188/482 (39%), Positives = 258/482 (53%), Gaps = 20/482 (4%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
            +C +  CGS             P       +C+RG GE YRGT++TT  G  CQ W +  
Sbjct: 263  FCDLTRCGSEAQ----------PRHESTTLNCFRGKGEGYRGTANTTAAGVPCQRWDAQK 312

Query: 182  PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFP 361
            PH+H   P  +    L  N+CRNPD  ++PWC+T+ P +R  +C                
Sbjct: 313  PHQHRFAPEKYACKDLRENFCRNPDGSEAPWCFTSRPGMRVAFC---------------- 356

Query: 362  AIVQVPSVED--LSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRA 535
               Q+P   D    EDC  G G+RYRG  + T  GVPCQ W+A+ PH+   FT  + P A
Sbjct: 357  --YQIPRCADDVRPEDCYNGVGERYRGSVSRTRKGVPCQHWSAEMPHKPQ-FTAISAPDA 413

Query: 536  GLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETSS------------FD-CGK-- 670
             LE+N+CRNPD D +GPWCYTT+P   FDYC + +C+               F+ CGK  
Sbjct: 414  HLEENFCRNPDRDSHGPWCYTTDPGTPFDYCALRRCDDDQPPSILEPPDQVVFEKCGKRV 473

Query: 671  PKMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSS 850
             +++ ++   RVVGG    P + PW +SLR R G HFCGG+L+  +WVLTA+ C      
Sbjct: 474  TRLDQQRSKLRVVGG---QPGNSPWTVSLRNRQGQHFCGGSLVKEQWVLTARQCFSSCHV 530

Query: 851  P-SSYKVILGA-HEEHHLGE-GVQEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACL 1021
            P   Y+V LG   +    GE G+Q+I V+K+   PSG+ + LLKL  P  +  +V   CL
Sbjct: 531  PLMGYEVWLGTLFQNPQPGEPGLQQIPVAKMVCGPSGSQLVLLKLERPVTLNQRVALICL 590

Query: 1022 PTPNYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCA 1201
            P   YVV   T C I GWGETKGT    +L  A L VI N+ CN      G++  NE+C 
Sbjct: 591  PPERYVVPPGTKCEIAGWGETKGTGNNKVLNVASLNVISNQECNIKH--RGRIRENEMCT 648

Query: 1202 GHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEI 1381
              L   + +C+GD GGPL CF  D ++L+G+      CA P  P +++RV  F  WI ++
Sbjct: 649  EGLLAPVGACEGDYGGPLACFTHDCWVLEGIIIPNRVCARPRWPAIFMRVSVFTDWIHKV 708

Query: 1382 MR 1387
            M+
Sbjct: 709  MQ 710



 Score =  172 bits (435), Expect = 9e-43
 Identities = 82/184 (44%), Positives = 103/184 (55%), Gaps = 1/184 (0%)
 Frame = +2

Query: 95  CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPW 274
           C   NGE YRG    T +GR+CQ W    PH H   PG F +  L  NYCRNPD  + PW
Sbjct: 192 CVWCNGEDYRGAVDRTQSGRECQRWDLQHPHAHPFEPGKFLDKDLDDNYCRNPDGSERPW 251

Query: 275 CYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRGKRATTV 454
           CYTTDP+V  E+C+L +C    Q           P  E  + +C  G G+ YRG   TT 
Sbjct: 252 CYTTDPQVEREFCDLTRCGSEAQ-----------PRHESTTLNCFRGKGEGYRGTANTTA 300

Query: 455 AGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC-D 631
           AGVPCQ W AQ+PH+H  F PE      L +N+CRNPDG +  PWC+T+ P     +C  
Sbjct: 301 AGVPCQRWDAQKPHQHR-FAPEKYACKDLRENFCRNPDGSE-APWCFTSRPGMRVAFCYQ 358

Query: 632 VPQC 643
           +P+C
Sbjct: 359 IPRC 362



 Score =  146 bits (368), Expect = 6e-35
 Identities = 80/205 (39%), Positives = 103/205 (50%), Gaps = 9/205 (4%)
 Frame = +2

Query: 95  CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKS-P 271
           C   NG  YRGT + T  G  CQ W    P+ H+ TP      GL  N+CRNPD D   P
Sbjct: 111 CITDNGVKYRGTVAITTGGLPCQHWSHRFPNDHKYTPTL--RNGLEENFCRNPDRDPGGP 168

Query: 272 WCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRGKRATT 451
           WCYTTDP VR++ C +K C E                       C++ NG+ YRG    T
Sbjct: 169 WCYTTDPAVRFQSCGIKSCREAA---------------------CVWCNGEDYRGAVDRT 207

Query: 452 VAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCD 631
            +G  CQ W  Q PH H  F P       L+ NYCRNPDG +  PWCYTT+PQ   ++CD
Sbjct: 208 QSGRECQRWDLQHPHAHP-FEPGKFLDKDLDDNYCRNPDGSER-PWCYTTDPQVEREFCD 265

Query: 632 VPQC--------ETSSFDCGKPKME 682
           + +C        E+++ +C + K E
Sbjct: 266 LTRCGSEAQPRHESTTLNCFRGKGE 290



 Score = 90.5 bits (223), Expect = 4e-18
 Identities = 40/90 (44%), Positives = 54/90 (60%)
 Frame = +2

Query: 386 EDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNP 565
           +D    C+  NG +YRG  A T  G+PCQ W+ + P+ H  +TP    R GLE+N+CRNP
Sbjct: 105 KDYVRTCITDNGVKYRGTVAITTGGLPCQHWSHRFPNDHK-YTPTL--RNGLEENFCRNP 161

Query: 566 DGDDNGPWCYTTNPQKLFDYCDVPQCETSS 655
           D D  GPWCYTT+P   F  C +  C  ++
Sbjct: 162 DRDPGGPWCYTTDPAVRFQSCGIKSCREAA 191


>ref|NP_001002964.1| hepatocyte growth factor [Canis familiaris]
          Length = 730

 Score =  322 bits (824), Expect = 7e-88
 Identities = 185/480 (38%), Positives = 254/480 (52%), Gaps = 19/480 (3%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
            YC I  C  ST +    D  VP E T    +C +G GE YRGT +T   G  CQ W S  
Sbjct: 282  YCAIKMCAHSTMN----DTDVPMETT----ECIQGQGEGYRGTINTIWNGVPCQRWDSQY 333

Query: 182  PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFP 361
            PH+H+ TP NF    L  NYCRNPD  +SPWC+TTDP +R  YC+               
Sbjct: 334  PHQHDITPENFKCKDLRENYCRNPDGAESPWCFTTDPNIRVGYCS--------------- 378

Query: 362  AIVQVPSVEDLS-EDCMFGNGKRYRGKRATTVAGVPCQEWAA--QEPHRHSIFTPETNPR 532
               Q+P  +  S +DC  GNGK Y G  + T +G+ C  W    ++ HRH  + P+ +  
Sbjct: 379  ---QIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWEKNMEDLHRHIFWEPDASK- 434

Query: 533  AGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETSS-----------FDCGKPKM 679
              L KNYCRNPD D +GPWCYT NP   +DYC + +CE  +             C K K 
Sbjct: 435  --LNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPIFRCEGDTTPTIVNLDHPVISCAKTKQ 492

Query: 680  EPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCL-EKSSSPS 856
                   RVV G +    +  W +SL+ R   H CGG+LI   W+LTA+ C   ++    
Sbjct: 493  ------LRVVNG-IPTRTNVGWMVSLKYR-NKHICGGSLIKESWILTARQCFPSRNRDLK 544

Query: 857  SYKVILGAHEEHHLGEGV--QEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLPTP 1030
             Y+  LG H+ H  G+    Q ++VS+L   P G+D+ LLKL+ PA++ D V    LP  
Sbjct: 545  DYEAWLGIHDVHGKGDEKRKQVLNVSQLVYGPEGSDLVLLKLARPAILDDFVSTIDLPNY 604

Query: 1031 NYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPN--ELCAG 1204
               + ++T C + GWG T      GLL+ A L ++ N+ C++Y    GKV+ N  E+CAG
Sbjct: 605  GCTIPEKTTCSVYGWGYTGSINFDGLLRVAHLYIMGNEKCSQYHQ--GKVTLNESEICAG 662

Query: 1205 HLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIM 1384
                    C+GD GGPLVC +    ++ GV   G GCA+PN+PG++VRV  +  WI +I+
Sbjct: 663  AENIVSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 722



 Score =  181 bits (459), Expect = 2e-45
 Identities = 90/215 (41%), Positives = 115/215 (53%), Gaps = 1/215 (0%)
 Frame = +2

Query: 14  PSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRH 193
           P C +S     Y    +P         C   NGESYRG    T +G+ CQ W   TPHRH
Sbjct: 187 PWCFTSNPEVRYEVCDIPQCSEVECMTC---NGESYRGPMDHTESGKICQRWDHQTPHRH 243

Query: 194 EKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQ 373
           +  P  +P+ G   NYCRNPD    PWCYT DP   WEYC +K C+ +    T+ P    
Sbjct: 244 KFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMCAHSTMNDTDVPM--- 300

Query: 374 VPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNY 553
                  + +C+ G G+ YRG   T   GVPCQ W +Q PH+H I TPE      L +NY
Sbjct: 301 ------ETTECIQGQGEGYRGTINTIWNGVPCQRWDSQYPHQHDI-TPENFKCKDLRENY 353

Query: 554 CRNPDGDDNGPWCYTTNPQKLFDYC-DVPQCETSS 655
           CRNPDG ++ PWC+TT+P     YC  +P+C+ SS
Sbjct: 354 CRNPDGAES-PWCFTTDPNIRVGYCSQIPKCDVSS 387



 Score =  168 bits (425), Expect = 1e-41
 Identities = 84/209 (40%), Positives = 109/209 (52%), Gaps = 1/209 (0%)
 Frame = +2

Query: 71  EQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRN 250
           E     ++C  G G SY+GT S T +G KCQ W SM PH H   P ++    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 251 PDADK-SPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKR 427
           P  ++  PWC+T++P VR+E C++ +CSE E                     CM  NG+ 
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE---------------------CMTCNGES 218

Query: 428 YRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNP 607
           YRG    T +G  CQ W  Q PHRH  F PE  P  G + NYCRNPDG    PWCYT +P
Sbjct: 219 YRGPMDHTESGKICQRWDHQTPHRHK-FLPERYPDKGFDDNYCRNPDGKPR-PWCYTLDP 276

Query: 608 QKLFDYCDVPQCETSSFDCGKPKMEPKKC 694
              ++YC +  C  S+ +     ME  +C
Sbjct: 277 DTPWEYCAIKMCAHSTMNDTDVPMETTEC 305


>ref|XP_539955.2| PREDICTED: similar to Tissue-type plasminogen activator precursor
            (tPA) (t-PA) (t-plasminogen activator) [Canis familiaris]
          Length = 560

 Score =  260 bits (664), Expect = 3e-69
 Identities = 165/462 (35%), Positives = 231/462 (50%), Gaps = 31/462 (6%)
 Frame = +2

Query: 95   CYRGNGESYRGTSSTTITGRKCQSW----VSMTPHRHEKTPGNFPNAGLTMNYCRNPDAD 262
            CY+  G SYRGT ST  +G +C +W    +++ P+   +        G + NYCRNPD D
Sbjct: 124  CYKDQGISYRGTWSTAESGAECANWNSSALALKPYSARRPHAVRLGLG-SHNYCRNPDGD 182

Query: 263  KSPWCYTTDP-RVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRGK 439
              PWCY     +   E+C+   C + +                  +EDC FG G  YRG 
Sbjct: 183  LRPWCYVFKAGKYSTEFCSTPACPKEK------------------NEDCYFGKGLAYRGT 224

Query: 440  RATTVAGVPCQEWAAQEPHRHSIFTPETNPRA-GL-EKNYCRNPDGDDNGPWCYTTNPQK 613
             + T +G PC  W ++        T +TN +A GL   NYCRNPDGD   PWC+    +K
Sbjct: 225  YSFTTSGTPCLPWNSRVLAGKFYTTWKTNAQALGLGSHNYCRNPDGDAK-PWCHVLKDRK 283

Query: 614  L-FDYCDVPQCETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISL---RRRYGGH- 778
            L ++YCDVPQC T    CG      K+   R+ GG  +   S PWQ ++    RR  G  
Sbjct: 284  LTWEYCDVPQCST----CGLRHY--KQPQFRIKGGLYADITSHPWQAAIFVKNRRSPGER 337

Query: 779  -FCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLFKEPS-- 949
             FCGG LIS  WVL+A HC ++   P   KV+LG       GE  Q+ +V K        
Sbjct: 338  FFCGGILISSCWVLSAAHCFQERYPPHQLKVVLGRTYREVPGEKEQKFEVEKYITHKEFD 397

Query: 950  ----GADIALLKLSSPAVI----TDKVIPACLPTPNYVVADRTACYITGWG--ETKGTYG 1099
                  DIALLKL S ++     +D V  ACLP  +  + D T C ++G+G  E    + 
Sbjct: 398  DDTYNNDIALLKLQSDSLHCAQESDAVRTACLPEADLQLPDWTECELSGYGKHEASSPFY 457

Query: 1100 AGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAGHLAGG------IDSCQGDSGGPLVC 1261
            +  LKEA + +  +  C         ++ N LCAG    G       D+CQGDSGGPLVC
Sbjct: 458  SERLKEAHVRLYPSSRCTSRHLFNKTITNNMLCAGDTRSGGNQANLHDACQGDSGGPLVC 517

Query: 1262 FEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIMR 1387
             + ++  L G+ SWG+GC   + PG+Y +V  ++ WI++ M+
Sbjct: 518  MKDNRMTLVGIISWGIGCGQKDVPGIYTKVTNYLDWIQDNMQ 559



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 41/102 (40%), Positives = 56/102 (54%), Gaps = 4/102 (3%)
 Frame = +2

Query: 38  STEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVS--MTPHRHEKTPGN 211
           STE+   P  P++    +DCY G G +YRGT S T +G  C  W S  +    +     N
Sbjct: 196 STEFCSTPACPKEKN--EDCYFGKGLAYRGTYSFTTSGTPCLPWNSRVLAGKFYTTWKTN 253

Query: 212 FPNAGL-TMNYCRNPDADKSPWCYT-TDPRVRWEYCNLKKCS 331
               GL + NYCRNPD D  PWC+   D ++ WEYC++ +CS
Sbjct: 254 AQALGLGSHNYCRNPDGDAKPWCHVLKDRKLTWEYCDVPQCS 295


>ref|XP_541697.2| PREDICTED: similar to Serine protease hepsin (Transmembrane protease,
            serine 1) [Canis familiaris]
          Length = 417

 Score =  205 bits (522), Expect = 8e-53
 Identities = 126/332 (37%), Positives = 176/332 (53%), Gaps = 20/332 (6%)
 Frame = +2

Query: 452  VAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCD 631
            VAG+ C+E        HS     T    G    +C      D G         ++   CD
Sbjct: 85   VAGLSCEEMGFLRALGHSELDVRTAGANGTSGFFCV-----DEGRLPLARRLLEVISVCD 139

Query: 632  VPQ---CETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLIS 802
             P+     T   DCG+ K+       R+VGG  +    WPWQ+SLR   G H CGG+L+S
Sbjct: 140  CPRGRFLATVCQDCGRRKLPVD----RIVGGQDTSLGRWPWQVSLRYD-GAHLCGGSLLS 194

Query: 803  PEWVLTAKHCL-EKSSSPSSYKVILGAHEE---HHLGEGVQEIDVSK---LFKEPSGA-- 955
             +WVLTA HC  E++   S ++V  GA  +   H L  GVQ +        F++P+    
Sbjct: 195  GDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEEN 254

Query: 956  --DIALLKLSSPAVITDKVIPACLPTPNYVVADRTACYITGWGETKGTYG--AGLLKEAR 1123
              DIAL+ LSSP  +T+ + P CLP     + D   C +TGWG T+  YG  AG+L+EAR
Sbjct: 255  SNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQEAR 313

Query: 1124 LPVIENKVCNRYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEK----DKYILQG 1291
            +P+I N++CN  ++   ++ P   CAG+  GGID+CQGDSGGP VC +      ++ L G
Sbjct: 314  VPIISNELCNGPDFYANQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCG 373

Query: 1292 VTSWGLGCALPNKPGVYVRVXRFVTWIEEIMR 1387
            + SWG GCAL  KPGVY +V  F  WI + ++
Sbjct: 374  IVSWGTGCALAQKPGVYTKVSDFREWIFQAIK 405


>ref|XP_535016.2| PREDICTED: similar to hyaluronan binding protein 2 [Canis familiaris]
          Length = 565

 Score =  201 bits (511), Expect = 1e-51
 Identities = 154/480 (32%), Positives = 218/480 (45%), Gaps = 52/480 (10%)
 Frame = +2

Query: 107  NGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMN------YCRNPDADKS 268
            NGE++  +     +G +CQ+      ++ ++ P +     +T +       CR+P   K 
Sbjct: 97   NGENFTCSCPVPFSGNRCQN----VQNKCKENPCDRGECLITQSPPYYHCACRHPY--KG 150

Query: 269  PWCYTTDPRVRWEYC-NLKKCSETEQQ---VTNFPAIVQVPSVEDLSEDCMFGNGKRYRG 436
            P C    P  R   C N   CS   ++       P   +    E   +DC  G+G  YRG
Sbjct: 151  PDCSRAVPVCRPNPCQNGGTCSRQRRRSKFTCTCPDQFKGKFCEIGPDDCYVGDGYSYRG 210

Query: 437  KRATTVAGVPCQEWAAQE--PHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCY--TTN 604
            K + TV    C  W +       ++IF  +       E N+CRNPDGD   PWC+    N
Sbjct: 211  KVSKTVNQHSCLYWNSHLLLHENYNIFMEDAEAHGIGEHNFCRNPDGDKK-PWCFIKANN 269

Query: 605  PQKLFDYCDVPQCET-----------------SSFD-CGKPKMEPKKCPARVVGGCVSIP 730
             +  ++YCDV  C                     FD CG+ +M  K    R+ GG  S  
Sbjct: 270  AKLKWEYCDVSACSALDIADPEGSLTEPLTKLPGFDSCGRTEMTKKV--KRIYGGFKSTA 327

Query: 731  HSWPWQISLRRRYG-------GHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEE 889
               PWQ SL+           GHFCGG LI P WVLTA HC    +   +  V+LG  + 
Sbjct: 328  GKHPWQASLQTSLPLTVSMPQGHFCGGALIHPCWVLTAAHCTNIKARHLT--VVLGDQDL 385

Query: 890  HHLGEGVQEIDVSKLFK--------EPSGADIALLKLSSP----AVITDKVIPACLPTPN 1033
                   Q   V K+FK        E    DIALLKL       A+ +  V   CLP  N
Sbjct: 386  KKTEFHEQRFGVEKIFKYSLYNEREEIPHNDIALLKLKPVDGHCALESKYVKTVCLP--N 443

Query: 1034 YVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAGHLA 1213
                  T C+I+GWG T+   G+  L +A++ +I N +CN  +     +  + +CAG+L 
Sbjct: 444  SAFPSGTECHISGWGVTETGEGSRQLLDAKVRLIANTLCNSRQLYDHMIGDSMICAGNLQ 503

Query: 1214 G-GIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIMRR 1390
              G DSCQGDSGGPL C +   Y + G+ SWGL C    KPGVY +V +F+ WI+  +++
Sbjct: 504  KPGQDSCQGDSGGPLTCEKNGTYYVYGIVSWGLECG--KKPGVYTQVAKFLNWIKATIQK 561



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 42/137 (30%), Positives = 63/137 (45%), Gaps = 10/137 (7%)
 Frame = +2

Query: 92  DCYRGNGESYRGTSSTTITGRKCQSWVS--MTPHRHEKTPGNFPNAGL-TMNYCRNPDAD 262
           DCY G+G SYRG  S T+    C  W S  +    +     +    G+   N+CRNPD D
Sbjct: 199 DCYVGDGYSYRGKVSKTVNQHSCLYWNSHLLLHENYNIFMEDAEAHGIGEHNFCRNPDGD 258

Query: 263 KSPWCY--TTDPRVRWEYCNLKKCS-----ETEQQVTNFPAIVQVPSVEDLSEDCMFGNG 421
           K PWC+    + +++WEYC++  CS     + E  +T    + ++P  +      M    
Sbjct: 259 KKPWCFIKANNAKLKWEYCDVSACSALDIADPEGSLTE--PLTKLPGFDSCGRTEMTKKV 316

Query: 422 KRYRGKRATTVAGVPCQ 472
           KR  G   +T    P Q
Sbjct: 317 KRIYGGFKSTAGKHPWQ 333


>ref|XP_853682.1| PREDICTED: similar to Transmembrane protease, serine 3 (Serine
            protease TADG-12) (Tumor associated
            differentially-expressed gene-12 protein) [Canis
            familiaris]
          Length = 513

 Score =  200 bits (509), Expect = 2e-51
 Identities = 110/257 (42%), Positives = 148/257 (57%), Gaps = 16/257 (6%)
 Frame = +2

Query: 662  CGKPKMEPKKCPA---------RVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWV 814
            C   ++   KC A         R+VGG  S    WPWQ SL+ + G H CGG++I+P WV
Sbjct: 192  CASGRVVTLKCTACGLRMGYSSRIVGGNASSLTQWPWQASLQFQ-GYHLCGGSVITPVWV 250

Query: 815  LTAKHCLEKSSSPSSYKV------ILGAHEEHHLGEGVQEIDVSKLFKEPSGADIALLKL 976
            +TA HC+     P S+ V      +L +    HL E +  I  SK   +  G DIAL+KL
Sbjct: 251  VTAAHCVYDLYVPKSWTVQVGLVSLLDSPAPSHLVEKI--IYHSKYKPKRLGNDIALMKL 308

Query: 977  SSPAVITDKVIPACLPTPNYVVADRTACYITGWGETK-GTYGAGLLKEARLPVIENKVCN 1153
            + P    +++ P CLP       D   C+ +GWG T+ G   +  L  A +P+I NK+CN
Sbjct: 309  AGPVPFNERIQPVCLPNSEENFPDGKMCWTSGWGATEDGGDASPDLNHAAVPLISNKICN 368

Query: 1154 RYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKP 1333
              +  GG +SP+ LCAG+L GG+DSCQGDSGGPLVC E+  + L G TS+G+GCA  NKP
Sbjct: 369  HRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERRVWKLVGATSFGIGCADVNKP 428

Query: 1334 GVYVRVXRFVTWIEEIM 1384
            GVY R+  F+ WI E M
Sbjct: 429  GVYTRITSFLDWIHEQM 445


>ref|XP_850538.1| PREDICTED: hepatocyte growth factor activator isoform 1 [Canis
            familiaris]
          Length = 654

 Score =  200 bits (508), Expect = 3e-51
 Identities = 125/369 (33%), Positives = 174/369 (47%), Gaps = 41/369 (11%)
 Frame = +2

Query: 395  SEDCMFGNGKRYRGKRATTVAGVPCQEWAA----QEPHRHSIFTPETNPRAGLEKN-YCR 559
            S+ C  GNG  YRG  +T  +G+ C  W +    QE H  S+         GL  + YCR
Sbjct: 281  SQRCFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAAL---LGLGPHAYCR 337

Query: 560  NPDGDDNGPWCYTTNPQKL-FDYCDVPQCETSSF---------------------DCGKP 673
            NPD D+  PWCY      L ++YC +  CE+ +                       CGK 
Sbjct: 338  NPDKDER-PWCYVVKDSALSWEYCRLAACESLARIPSLTTAVLLSQAEPAPVGRQTCGKR 396

Query: 674  KMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSSP 853
              +      R++GG  S+P S PW  ++    G  FC G+L+   WV++A HC   S   
Sbjct: 397  HKKRTFLRPRIIGGSSSLPGSHPWLAAIY--IGDSFCAGSLVHTCWVVSAAHCFSNSPRR 454

Query: 854  SSYKVILGAHEEHHLGEGVQEIDVSKLFK-------EPSGADIALLKLSSP----AVITD 1000
             S  V+LG H  +   +  Q   + K           PS  D+ L++L       A+ + 
Sbjct: 455  ESVLVVLGQHFFNQTTDVTQTFGIEKYIPYPMYSVFNPSDHDLVLIRLKKKGDRCAIRSQ 514

Query: 1001 KVIPACLPTPNYVVADRTACYITGWG---ETKGTYGAGLLKEARLPVIENKVCNRYEYLG 1171
             V P CLP P+        C I GWG   E    Y + L +EA +P++ +  C+  E  G
Sbjct: 515  FVQPICLPEPSSPFPAGHKCQIAGWGHQDENVSGYSSSL-REALVPLVADHKCSSPEVYG 573

Query: 1172 GKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRV 1351
              +SPN LCAG+     D+CQGDSGGPL C +     L G+ SWG GC   NKPGVY RV
Sbjct: 574  ADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLNKPGVYTRV 633

Query: 1352 XRFVTWIEE 1378
             ++V WI++
Sbjct: 634  AKYVDWIKD 642



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 36/85 (42%), Positives = 46/85 (54%), Gaps = 4/85 (4%)
 Frame = +2

Query: 86  AQDCYRGNGESYRGTSSTTITGRKCQSWVS--MTPHRHEKTPGNFPNAGLTMN-YCRNPD 256
           +Q C+ GNG  YRG +ST  +G  C +W S  +    H  + G     GL  + YCRNPD
Sbjct: 281 SQRCFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPD 340

Query: 257 ADKSPWCYTT-DPRVRWEYCNLKKC 328
            D+ PWCY   D  + WEYC L  C
Sbjct: 341 KDERPWCYVVKDSALSWEYCRLAAC 365


>ref|XP_861645.1| PREDICTED: hepatocyte growth factor activator isoform 2 [Canis
            familiaris]
          Length = 657

 Score =  200 bits (508), Expect = 3e-51
 Identities = 125/369 (33%), Positives = 174/369 (47%), Gaps = 41/369 (11%)
 Frame = +2

Query: 395  SEDCMFGNGKRYRGKRATTVAGVPCQEWAA----QEPHRHSIFTPETNPRAGLEKN-YCR 559
            S+ C  GNG  YRG  +T  +G+ C  W +    QE H  S+         GL  + YCR
Sbjct: 284  SQRCFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAAL---LGLGPHAYCR 340

Query: 560  NPDGDDNGPWCYTTNPQKL-FDYCDVPQCETSSF---------------------DCGKP 673
            NPD D+  PWCY      L ++YC +  CE+ +                       CGK 
Sbjct: 341  NPDKDER-PWCYVVKDSALSWEYCRLAACESLARIPSLTTAVLLSQAEPAPVGRQTCGKR 399

Query: 674  KMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSSP 853
              +      R++GG  S+P S PW  ++    G  FC G+L+   WV++A HC   S   
Sbjct: 400  HKKRTFLRPRIIGGSSSLPGSHPWLAAIY--IGDSFCAGSLVHTCWVVSAAHCFSNSPRR 457

Query: 854  SSYKVILGAHEEHHLGEGVQEIDVSKLFK-------EPSGADIALLKLSSP----AVITD 1000
             S  V+LG H  +   +  Q   + K           PS  D+ L++L       A+ + 
Sbjct: 458  ESVLVVLGQHFFNQTTDVTQTFGIEKYIPYPMYSVFNPSDHDLVLIRLKKKGDRCAIRSQ 517

Query: 1001 KVIPACLPTPNYVVADRTACYITGWG---ETKGTYGAGLLKEARLPVIENKVCNRYEYLG 1171
             V P CLP P+        C I GWG   E    Y + L +EA +P++ +  C+  E  G
Sbjct: 518  FVQPICLPEPSSPFPAGHKCQIAGWGHQDENVSGYSSSL-REALVPLVADHKCSSPEVYG 576

Query: 1172 GKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRV 1351
              +SPN LCAG+     D+CQGDSGGPL C +     L G+ SWG GC   NKPGVY RV
Sbjct: 577  ADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLNKPGVYTRV 636

Query: 1352 XRFVTWIEE 1378
             ++V WI++
Sbjct: 637  AKYVDWIKD 645



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 36/85 (42%), Positives = 46/85 (54%), Gaps = 4/85 (4%)
 Frame = +2

Query: 86  AQDCYRGNGESYRGTSSTTITGRKCQSWVS--MTPHRHEKTPGNFPNAGLTMN-YCRNPD 256
           +Q C+ GNG  YRG +ST  +G  C +W S  +    H  + G     GL  + YCRNPD
Sbjct: 284 SQRCFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPD 343

Query: 257 ADKSPWCYTT-DPRVRWEYCNLKKC 328
            D+ PWCY   D  + WEYC L  C
Sbjct: 344 KDERPWCYVVKDSALSWEYCRLAAC 368


>ref|NP_001026985.1| HGF activator [Canis familiaris]
          Length = 654

 Score =  200 bits (508), Expect = 3e-51
 Identities = 125/369 (33%), Positives = 174/369 (47%), Gaps = 41/369 (11%)
 Frame = +2

Query: 395  SEDCMFGNGKRYRGKRATTVAGVPCQEWAA----QEPHRHSIFTPETNPRAGLEKN-YCR 559
            S+ C  GNG  YRG  +T  +G+ C  W +    QE H  S+         GL  + YCR
Sbjct: 281  SQRCFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAAL---LGLGPHAYCR 337

Query: 560  NPDGDDNGPWCYTTNPQKL-FDYCDVPQCETSSF---------------------DCGKP 673
            NPD D+  PWCY      L ++YC +  CE+ +                       CGK 
Sbjct: 338  NPDKDER-PWCYVVKDSALSWEYCRLAACESLARIPSLTTAVLLSQAEPAPVGRQTCGKR 396

Query: 674  KMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSSP 853
              +      R++GG  S+P S PW  ++    G  FC G+L+   WV++A HC   S   
Sbjct: 397  HKKRTFLRPRIIGGSSSLPGSHPWLAAIY--IGDSFCAGSLVHTCWVVSAAHCFSNSPRR 454

Query: 854  SSYKVILGAHEEHHLGEGVQEIDVSKLFK-------EPSGADIALLKLSSP----AVITD 1000
             S  V+LG H  +   +  Q   + K           PS  D+ L++L       A+ + 
Sbjct: 455  ESVLVVLGQHFFNQTTDVTQTFGIEKYIPYPMYSVFNPSDHDLVLIRLKKKGDRCAIRSQ 514

Query: 1001 KVIPACLPTPNYVVADRTACYITGWG---ETKGTYGAGLLKEARLPVIENKVCNRYEYLG 1171
             V P CLP P+        C I GWG   E    Y + L +EA +P++ +  C+  E  G
Sbjct: 515  FVQPICLPEPSSPFPAGHKCQIAGWGHQDENVSGYSSSL-REALVPLVADHKCSSPEVYG 573

Query: 1172 GKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRV 1351
              +SPN LCAG+     D+CQGDSGGPL C +     L G+ SWG GC   NKPGVY RV
Sbjct: 574  ADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLNKPGVYTRV 633

Query: 1352 XRFVTWIEE 1378
             ++V WI++
Sbjct: 634  AKYVDWIKD 642



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 36/85 (42%), Positives = 46/85 (54%), Gaps = 4/85 (4%)
 Frame = +2

Query: 86  AQDCYRGNGESYRGTSSTTITGRKCQSWVS--MTPHRHEKTPGNFPNAGLTMN-YCRNPD 256
           +Q C+ GNG  YRG +ST  +G  C +W S  +    H  + G     GL  + YCRNPD
Sbjct: 281 SQRCFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPD 340

Query: 257 ADKSPWCYTT-DPRVRWEYCNLKKC 328
            D+ PWCY   D  + WEYC L  C
Sbjct: 341 KDERPWCYVVKDSALSWEYCRLAAC 365


  Database: RefSeqCP
    Posted date:  Aug 1, 2006  9:25 PM
  Number of letters in database: 19,266,565
  Number of sequences in database:  33,732
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,451,859
Number of Sequences: 33732
Number of extensions: 2089486
Number of successful extensions: 9295
Number of sequences better than 1.0e-05: 10
Number of HSP's better than  0.0 without gapping: 6224
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8748
length of database: 19,266,565
effective HSP length: 107
effective length of database: 15,657,241
effective search space used: 5730550206
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)


Search to RefSeqMP
BLASTX 2.2.10 [Oct-19-2004]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20060611C-000407
         (1422 letters)

Database: RefSeqMP 
           45,328 sequences; 21,768,885 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_032903.2| plasminogen [Mus musculus]                           768   0.0  
Alignment   gi|NP_032269.2| macrophage stimulating 1 (hepatocyte growth fac...   346   4e-95
Alignment   gi|NP_034557.2| hepatocyte growth factor [Mus musculus]              321   1e-87
Alignment   gi|NP_032898.1| plasminogen activator, tissue [Mus musculus]         241   2e-63
Alignment   gi|NP_067464.1| coagulation factor XII (Hageman factor) [Mus mu...   207   3e-53
Alignment   gi|NP_542765.1| transmembrane protease, serine 3 [Mus musculus]      204   2e-52
Alignment   gi|NP_032307.1| hepsin [Mus musculus]                                202   5e-52
Alignment   gi|NP_062320.1| hepatocyte growth factor activator [Mus musculus]    199   5e-51
Alignment   gi|NP_666213.1| hyaluronic acid binding protein 2 [Mus musculus]     199   8e-51
Alignment   gi|XP_926294.1| PREDICTED: similar to protease, serine, 33 isof...   195   1e-49

>ref|NP_032903.2| plasminogen [Mus musculus]
          Length = 812

 Score =  768 bits (1982), Expect = 0.0
 Identities = 357/468 (76%), Positives = 391/468 (83%), Gaps = 4/468 (0%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAPVPPE-QTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSM 178
            YC+IPSC SS  S +  D+ VPPE QTPV Q+CY+ +G+SYRGTSSTTITG+KCQSW +M
Sbjct: 346  YCEIPSCESSA-SPDQSDSSVPPEEQTPVVQECYQSDGQSYRGTSSTTITGKKCQSWAAM 404

Query: 179  TPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNF 358
             PHRH KTP NFP+AGL MNYCRNPD DK PWCYTTDP VRWEYCNLK+CSET   V   
Sbjct: 405  FPHRHSKTPENFPDAGLEMNYCRNPDGDKGPWCYTTDPSVRWEYCNLKRCSETGGSVVEL 464

Query: 359  PAIVQVPSVEDLSE-DCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRA 535
            P + Q PS    SE DCM+GNGK YRGK A T AG PCQ WAAQEPHRHSIFTP+TNPRA
Sbjct: 465  PTVSQEPSGPSDSETDCMYGNGKDYRGKTAVTAAGTPCQGWAAQEPHRHSIFTPQTNPRA 524

Query: 536  GLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCET-SSFDCGKPKMEPKKCPARVVG 712
            GLEKNYCRNPDGD NGPWCYTTNP+KL+DYCD+P C + SSF+CGKP++EPKKCP RVVG
Sbjct: 525  GLEKNYCRNPDGDVNGPWCYTTNPRKLYDYCDIPLCASASSFECGKPQVEPKKCPGRVVG 584

Query: 713  GCVSIPHSWPWQISLRRRYGG-HFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEE 889
            GCV+ PHSWPWQISLR R+ G HFCGGTLI+PEWVLTA HCLEKSS P  YKVILGAHEE
Sbjct: 585  GCVANPHSWPWQISLRTRFTGQHFCGGTLIAPEWVLTAAHCLEKSSRPEFYKVILGAHEE 644

Query: 890  HHLGEGVQEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLPTPNYVVADRTACYIT 1069
            +  G  VQEI V+KL  EP+  DIALLKLS PA ITDKVIPACLP+PNY+VADRT CYIT
Sbjct: 645  YIRGSDVQEISVAKLILEPNNRDIALLKLSRPATITDKVIPACLPSPNYMVADRTICYIT 704

Query: 1070 GWGETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAGHLAGGIDSCQGDSGG 1249
            GWGET+GT+GAG LKEA+LPVIENKVCNR EYL  +V   ELCAG LAGG+DSCQGDSGG
Sbjct: 705  GWGETQGTFGAGRLKEAQLPVIENKVCNRVEYLNNRVKSTELCAGQLAGGVDSCQGDSGG 764

Query: 1250 PLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIMRRN 1393
            PLVCFEKDKYILQGVTSWGLGCA PNKPGVYVRV RFV WIE  MR N
Sbjct: 765  PLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVDWIEREMRNN 812



 Score =  225 bits (574), Expect = 8e-59
 Identities = 105/217 (48%), Positives = 134/217 (61%), Gaps = 3/217 (1%)
 Frame = +2

Query: 2   YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
           YC IP C +            PP  +P  Q C +G GE+YRGT S T++G+ CQ W   T
Sbjct: 256 YCDIPRCTTP-----------PPPPSPTYQ-CLKGRGENYRGTVSVTVSGKTCQRWSEQT 303

Query: 182 PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSET---EQQVT 352
           PHRH +TP NFP   L  NYCRNPD + +PWCYTTD ++RWEYC +  C  +   +Q  +
Sbjct: 304 PHRHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSQLRWEYCEIPSCESSASPDQSDS 363

Query: 353 NFPAIVQVPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPR 532
           + P   Q P V    ++C   +G+ YRG  +TT+ G  CQ WAA  PHRHS  TPE  P 
Sbjct: 364 SVPPEEQTPVV----QECYQSDGQSYRGTSSTTITGKKCQSWAAMFPHRHS-KTPENFPD 418

Query: 533 AGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQC 643
           AGLE NYCRNPDG D GPWCYTT+P   ++YC++ +C
Sbjct: 419 AGLEMNYCRNPDG-DKGPWCYTTDPSVRWEYCNLKRC 454



 Score =  195 bits (496), Expect = 9e-50
 Identities = 94/239 (39%), Positives = 125/239 (52%)
 Frame = +2

Query: 2   YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
           YC IP C                      ++C   +GE Y G  S T++G  CQ+W S +
Sbjct: 175 YCNIPEC---------------------EEECMYCSGEKYEGKISKTMSGLDCQAWDSQS 213

Query: 182 PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFP 361
           PH H   P  FP+  L MNYCRNPD +  PWC+TTDP  RWEYC++ +C+          
Sbjct: 214 PHAHGYIPAKFPSKNLKMNYCRNPDGEPRPWCFTTDPTKRWEYCDIPRCTTP-------- 265

Query: 362 AIVQVPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGL 541
                P     +  C+ G G+ YRG  + TV+G  CQ W+ Q PHRH+  TPE  P   L
Sbjct: 266 -----PPPPSPTYQCLKGRGENYRGTVSVTVSGKTCQRWSEQTPHRHN-RTPENFPCKNL 319

Query: 542 EKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETSSFDCGKPKMEPKKCPARVVGGC 718
           E+NYCRNPDG +  PWCYTT+ Q  ++YC++P CE+S+         P +    VV  C
Sbjct: 320 EENYCRNPDG-ETAPWCYTTDSQLRWEYCEIPSCESSASPDQSDSSVPPEEQTPVVQEC 377



 Score =  181 bits (459), Expect = 2e-45
 Identities = 87/216 (40%), Positives = 120/216 (55%), Gaps = 1/216 (0%)
 Frame = +2

Query: 5   CKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTP 184
           C I +  S T+S   +   +  E+     +C  G G  YRGT S T +G  CQ W +  P
Sbjct: 73  CVIMAENSKTSSIIRMRDVILFEKRVYLSECKTGIGNGYRGTMSRTKSGVACQKWGATFP 132

Query: 185 HRHEKTPGNFPNAGLTMNYCRNPDAD-KSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFP 361
           H    +P   PN GL  NYCRNPD D + PWCYTTDP  R++YCN+ +C           
Sbjct: 133 HVPNYSPSTHPNEGLEENYCRNPDNDEQGPWCYTTDPDKRYDYCNIPEC----------- 181

Query: 362 AIVQVPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGL 541
                       E+CM+ +G++Y GK + T++G+ CQ W +Q PH H  + P   P   L
Sbjct: 182 -----------EEECMYCSGEKYEGKISKTMSGLDCQAWDSQSPHAHG-YIPAKFPSKNL 229

Query: 542 EKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCET 649
           + NYCRNPDG+   PWC+TT+P K ++YCD+P+C T
Sbjct: 230 KMNYCRNPDGEPR-PWCFTTDPTKRWEYCDIPRCTT 264



 Score =  115 bits (288), Expect = 1e-25
 Identities = 48/96 (50%), Positives = 63/96 (65%)
 Frame = +2

Query: 401 DCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDN 580
           +C  G G  YRG  + T +GV CQ+W A  PH  + ++P T+P  GLE+NYCRNPD D+ 
Sbjct: 102 ECKTGIGNGYRGTMSRTKSGVACQKWGATFPHVPN-YSPSTHPNEGLEENYCRNPDNDEQ 160

Query: 581 GPWCYTTNPQKLFDYCDVPQCETSSFDCGKPKMEPK 688
           GPWCYTT+P K +DYC++P+CE     C   K E K
Sbjct: 161 GPWCYTTDPDKRYDYCNIPECEEECMYCSGEKYEGK 196


>ref|NP_032269.2| macrophage stimulating 1 (hepatocyte growth factor-like) [Mus
            musculus]
          Length = 716

 Score =  346 bits (887), Expect = 4e-95
 Identities = 185/480 (38%), Positives = 266/480 (55%), Gaps = 18/480 (3%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
            +C +PSCG +   T    +         A +C+RG GE YRGT++TT  G  CQ W + +
Sbjct: 262  FCDLPSCGPNLPPT-VKGSKSQRRNKGKALNCFRGKGEDYRGTTNTTSAGVPCQRWDAQS 320

Query: 182  PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCN-LKKCSETEQQVTNF 358
            PH+H   P  +    L  N+CRNPD  ++PWC+T+ P +R  +C+ + +C+E        
Sbjct: 321  PHQHRFVPEKYACKDLRENFCRNPDGSEAPWCFTSRPGLRMAFCHQIPRCTE-------- 372

Query: 359  PAIVQVPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAG 538
                     E + E C  G+G++YRG  + T  GV CQ W+++ PH+   FTP + P+AG
Sbjct: 373  ---------ELVPEGCYHGSGEQYRGSVSKTRKGVQCQHWSSETPHKPQ-FTPTSAPQAG 422

Query: 539  LEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCE----TSSFD---------CGKPKM 679
            LE N+CRNPDGD +GPWCYT +P  LFDYC + +C+     S  D         CGK   
Sbjct: 423  LEANFCRNPDGDSHGPWCYTLDPDILFDYCALQRCDDDQPPSILDPPDQVVFEKCGKRVD 482

Query: 680  EPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSSP-S 856
            +  K   RVVGG    P + PW +SLR R G HFCGG+L+  +WVLTA+ C+     P +
Sbjct: 483  KSNK--LRVVGG---HPGNSPWTVSLRNRQGQHFCGGSLVKEQWVLTARQCIWSCHEPLT 537

Query: 857  SYKVILGA-HEEHHLGE-GVQEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLPTP 1030
             Y+V LG  ++    GE  +Q + V+K    P+G+ + LLKL  P ++   V   CLP  
Sbjct: 538  GYEVWLGTINQNPQPGEANLQRVPVAKAVCGPAGSQLVLLKLERPVILNHHVALICLPPE 597

Query: 1031 NYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCN-RYEYLGGKVSPNELCAGH 1207
             YVV   T C I GWGE+ GT    +L  A + VI N+ CN +Y    G +  +E+C   
Sbjct: 598  QYVVPPGTKCEIAGWGESIGTSNNTVLHVASMNVISNQECNTKYR---GHIQESEICPQG 654

Query: 1208 LAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIMR 1387
            +   + +C+GD GGPL C+  D ++LQG+      CA P  P ++ RV  FV WI ++M+
Sbjct: 655  MVVPVGACEGDYGGPLACYTHDCWVLQGLIIPNRVCARPRWPAIFTRVFVFVDWINKVMQ 714



 Score =  163 bits (413), Expect = 4e-40
 Identities = 81/188 (43%), Positives = 102/188 (54%), Gaps = 5/188 (2%)
 Frame = +2

Query: 95  CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPW 274
           C   NGE YRG    T +GR+CQ W    PH H   P  F +  L  NYCRNPD  + PW
Sbjct: 191 CVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKDLKDNYCRNPDGSERPW 250

Query: 275 CYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSE----DCMFGNGKRYRGKR 442
           CYTTDP V  E+C+L  C        N P  V+    +  ++    +C  G G+ YRG  
Sbjct: 251 CYTTDPNVEREFCDLPSCG------PNLPPTVKGSKSQRRNKGKALNCFRGKGEDYRGTT 304

Query: 443 ATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFD 622
            TT AGVPCQ W AQ PH+H  F PE      L +N+CRNPDG +  PWC+T+ P     
Sbjct: 305 NTTSAGVPCQRWDAQSPHQHR-FVPEKYACKDLRENFCRNPDGSE-APWCFTSRPGLRMA 362

Query: 623 YC-DVPQC 643
           +C  +P+C
Sbjct: 363 FCHQIPRC 370



 Score =  150 bits (379), Expect = 3e-36
 Identities = 77/184 (41%), Positives = 97/184 (52%), Gaps = 1/184 (0%)
 Frame = +2

Query: 95  CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDAD-KSP 271
           C   NG SYRGT + T  G  CQ+W    P+ H+ TP   P  GL  N+CRNPD D + P
Sbjct: 110 CIMDNGVSYRGTVARTAGGLPCQAWSRRFPNDHKYTP--TPKNGLEENFCRNPDGDPRGP 167

Query: 272 WCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKRYRGKRATT 451
           WCYTT+  VR++ C +K C E                       C+  NG+ YRG+   T
Sbjct: 168 WCYTTNRSVRFQSCGIKTCREAV---------------------CVLCNGEDYRGEVDVT 206

Query: 452 VAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCD 631
            +G  CQ W  Q PH H  F PE      L+ NYCRNPDG +  PWCYTT+P    ++CD
Sbjct: 207 ESGRECQRWDLQHPHSHP-FQPEKFLDKDLKDNYCRNPDGSER-PWCYTTDPNVEREFCD 264

Query: 632 VPQC 643
           +P C
Sbjct: 265 LPSC 268



 Score = 93.6 bits (231), Expect = 5e-19
 Identities = 41/86 (47%), Positives = 52/86 (60%)
 Frame = +2

Query: 386 EDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNP 565
           +D    C+  NG  YRG  A T  G+PCQ W+ + P+ H  +TP   P+ GLE+N+CRNP
Sbjct: 104 KDYVRTCIMDNGVSYRGTVARTAGGLPCQAWSRRFPNDHK-YTP--TPKNGLEENFCRNP 160

Query: 566 DGDDNGPWCYTTNPQKLFDYCDVPQC 643
           DGD  GPWCYTTN    F  C +  C
Sbjct: 161 DGDPRGPWCYTTNRSVRFQSCGIKTC 186


>ref|NP_034557.2| hepatocyte growth factor [Mus musculus]
          Length = 728

 Score =  321 bits (822), Expect = 1e-87
 Identities = 181/480 (37%), Positives = 257/480 (53%), Gaps = 19/480 (3%)
 Frame = +2

Query: 2    YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
            YC I +C  S  +    +  VP E T    +C +G GE YRGTS+T   G  CQ W S  
Sbjct: 283  YCAIKTCAHSAVN----ETDVPMETT----ECIQGQGEGYRGTSNTIWNGIPCQRWDSQY 334

Query: 182  PHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFP 361
            PH+H+ TP NF    L  NYCRNPD  +SPWC+TTDP +R  YC+               
Sbjct: 335  PHKHDITPENFKCKDLRENYCRNPDGAESPWCFTTDPNIRVGYCS--------------- 379

Query: 362  AIVQVPSVEDLS-EDCMFGNGKRYRGKRATTVAGVPCQEWAA--QEPHRHSIFTPETNPR 532
               Q+P  +  S +DC  GNGK Y G  + T +G+ C  W    ++ HRH  + P+ +  
Sbjct: 380  ---QIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWDKNMEDLHRHIFWEPDASK- 435

Query: 533  AGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDVPQCETSS-----------FDCGKPKM 679
              L KNYCRNPD D +GPWCYT NP   +DYC + +CE  +             C K K 
Sbjct: 436  --LNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTKQ 493

Query: 680  EPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLE-KSSSPS 856
                   RVV G +    +  W +SL+ R   H CGG+LI   WV+TA+ C   ++    
Sbjct: 494  ------LRVVNG-IPTQTTVGWMVSLKYR-NKHICGGSLIKESWVITARQCFPARNKDLK 545

Query: 857  SYKVILGAHEEHHLGEGVQE--IDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLPTP 1030
             Y+  LG H+ H  GE  ++  +++S+L   P G+D+ LLKL+ PA++ + V    LP+ 
Sbjct: 546  DYEAWLGIHDVHERGEEKRKQILNISQLVYGPEGSDLVLLKLARPAILDNFVSTIDLPSY 605

Query: 1031 NYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNE--LCAG 1204
               + ++T C I GWG T      GLL+ A L ++ N+ C+++    GKV+ NE  LCAG
Sbjct: 606  GCTIPEKTTCSIYGWGYTGLINADGLLRVAHLYIMGNEKCSQHHQ--GKVTLNESELCAG 663

Query: 1205 HLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIM 1384
                G   C+GD GGPL+C +    ++ GV   G GCA+PN+P ++VRV  +  WI +++
Sbjct: 664  AEKIGSGPCEGDYGGPLICEQHKMRMVLGVIVPGRGCAIPNRPVIFVRVAYYAKWIHKVI 723



 Score =  183 bits (464), Expect = 4e-46
 Identities = 89/215 (41%), Positives = 115/215 (53%), Gaps = 1/215 (0%)
 Frame = +2

Query: 14  PSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRH 193
           P C +S     Y    +P         C   NGESYRG    T +G+ CQ W   TPHRH
Sbjct: 188 PWCFTSNPEVRYEVCDIPQCSEVECMTC---NGESYRGPMDHTESGKTCQRWDQQTPHRH 244

Query: 194 EKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQ 373
           +  P  +P+ G   NYCRNPD    PWCYT DP   WEYC +K C+ +    T+ P    
Sbjct: 245 KFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTTWEYCAIKTCAHSAVNETDVPM--- 301

Query: 374 VPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNY 553
                  + +C+ G G+ YRG   T   G+PCQ W +Q PH+H I TPE      L +NY
Sbjct: 302 ------ETTECIQGQGEGYRGTSNTIWNGIPCQRWDSQYPHKHDI-TPENFKCKDLRENY 354

Query: 554 CRNPDGDDNGPWCYTTNPQKLFDYC-DVPQCETSS 655
           CRNPDG ++ PWC+TT+P     YC  +P+C+ SS
Sbjct: 355 CRNPDGAES-PWCFTTDPNIRVGYCSQIPKCDVSS 388



 Score =  169 bits (427), Expect = 9e-42
 Identities = 84/209 (40%), Positives = 109/209 (52%), Gaps = 1/209 (0%)
 Frame = +2

Query: 71  EQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRN 250
           E     ++C  G G SY+GT S T +G KCQ W SM PH H   P ++    L  NYCRN
Sbjct: 121 ENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRN 180

Query: 251 PDADK-SPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKR 427
           P  ++  PWC+T++P VR+E C++ +CSE E                     CM  NG+ 
Sbjct: 181 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE---------------------CMTCNGES 219

Query: 428 YRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNP 607
           YRG    T +G  CQ W  Q PHRH  F PE  P  G + NYCRNPDG    PWCYT +P
Sbjct: 220 YRGPMDHTESGKTCQRWDQQTPHRHK-FLPERYPDKGFDDNYCRNPDGKPR-PWCYTLDP 277

Query: 608 QKLFDYCDVPQCETSSFDCGKPKMEPKKC 694
              ++YC +  C  S+ +     ME  +C
Sbjct: 278 DTTWEYCAIKTCAHSAVNETDVPMETTEC 306


>ref|NP_032898.1| plasminogen activator, tissue [Mus musculus]
          Length = 559

 Score =  241 bits (614), Expect = 2e-63
 Identities = 165/466 (35%), Positives = 225/466 (48%), Gaps = 34/466 (7%)
 Frame = +2

Query: 95   CYRGNGESYRGTSSTTITGRKCQSW----VSMTPHRHEKTPGNFPNA---GL-TMNYCRN 250
            C+   G +YRGT ST  +G +C +W    +S+ P+   +     PNA   GL   NYCRN
Sbjct: 124  CFEEQGITYRGTWSTAESGAECINWNSSVLSLKPYNARR-----PNAIKLGLGNHNYCRN 178

Query: 251  PDADKSPWCYTTDP-RVRWEYCNLKKCSETEQQVTNFPAIVQVPSVEDLSEDCMFGNGKR 427
            PD D  PWCY     +   E+C+   C + +                  SEDC  G G  
Sbjct: 179  PDRDLKPWCYVFKAGKYTTEFCSTPACPKGK------------------SEDCYVGKGVT 220

Query: 428  YRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRA-GLEK-NYCRNPDGDDNGPWCYTT 601
            YRG  + T +   C  W +      S     TN +A GL + NYCRNPDGD   PWC+  
Sbjct: 221  YRGTHSLTTSQASCLPWNSIVLMGKSYTAWRTNSQALGLARHNYCRNPDGDAR-PWCHVM 279

Query: 602  NPQKL-FDYCDVPQCETSSFDCGKPKMEPKKCPARVVGGCVSIPHSWPWQISL----RRR 766
              +KL ++YCD+  C T    CG  +   K+   R+ GG  +   S PWQ ++    +R 
Sbjct: 280  KDRKLTWEYCDMSPCST----CGLRQY--KRPQFRIKGGLYTDITSHPWQAAIFVKNKRS 333

Query: 767  YGGHF-CGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLF-- 937
             G  F CGG LIS  WVL+A HC  +   P+  KV+LG       GE  Q  ++ K    
Sbjct: 334  PGERFLCGGVLISSCWVLSAAHCFLERFPPNHLKVVLGRTYRVVPGEEEQTFEIEKYIVH 393

Query: 938  ----KEPSGADIALLKLSSP----AVITDKVIPACLPTPNYVVADRTACYITGWG--ETK 1087
                 +    DIALL+L S     A  +  V  ACLP PN  + D T C ++G+G  E  
Sbjct: 394  EEFDDDTYDNDIALLQLRSQSKQCAQESSSVGTACLPDPNLQLPDWTECELSGYGKHEAS 453

Query: 1088 GTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAGHLAGG-----IDSCQGDSGGP 1252
              + +  LKEA + +  +  C         V+ N LCAG    G      D+CQGDSGGP
Sbjct: 454  SPFFSDRLKEAHVRLYPSSRCTSQHLFNKTVTNNMLCAGDTRSGGNQDLHDACQGDSGGP 513

Query: 1253 LVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIMRR 1390
            LVC    +  L G+ SWGLGC   + PGVY +V  ++ WI + M++
Sbjct: 514  LVCMINKQMTLTGIISWGLGCGQKDVPGVYTKVTNYLDWIHDNMKQ 559



 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 41/114 (35%), Positives = 57/114 (50%), Gaps = 4/114 (3%)
 Frame = +2

Query: 2   YCKIPSCGSSTTSTEYLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMT 181
           +C +   G  TT  E+   P  P+    ++DCY G G +YRGT S T +   C  W S+ 
Sbjct: 186 WCYVFKAGKYTT--EFCSTPACPKGK--SEDCYVGKGVTYRGTHSLTTSQASCLPWNSIV 241

Query: 182 PHRHEKTPGNFPNAGLTM---NYCRNPDADKSPWCYT-TDPRVRWEYCNLKKCS 331
                 T     +  L +   NYCRNPD D  PWC+   D ++ WEYC++  CS
Sbjct: 242 LMGKSYTAWRTNSQALGLARHNYCRNPDGDARPWCHVMKDRKLTWEYCDMSPCS 295


>ref|NP_067464.1| coagulation factor XII (Hageman factor) [Mus musculus]
          Length = 597

 Score =  207 bits (526), Expect = 3e-53
 Identities = 135/388 (34%), Positives = 190/388 (48%), Gaps = 58/388 (14%)
 Frame = +2

Query: 389  DLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKN-YCRNP 565
            DL   C  G G  YRG+  TT +G PCQ W  +  +R+   T +     GL  + +CRNP
Sbjct: 212  DLWATCYEGRGLSYRGQAGTTQSGAPCQRWTVEATYRN--MTEKQALSWGLGHHAFCRNP 269

Query: 566  DGDDNGPWCYTTNPQKL-FDYCDVPQCETSSF---------------------------- 658
            D D   PWC+  +  +L +DYC + QC+T +F                            
Sbjct: 270  DNDTR-PWCFVWSGDRLSWDYCGLEQCQTPTFAPLVVPESQEESPSQAPSLSHAPNDSTD 328

Query: 659  -----------DCGKPKMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISP 805
                        CG+   +      RVVGG V++P S P+  +L   +G +FC G+LI+P
Sbjct: 329  HQTSLSKTNTMGCGQRFRKGLSSFMRVVGGLVALPGSHPYIAALY--WGNNFCAGSLIAP 386

Query: 806  EWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVS--KLFKEPSGA----DIAL 967
             WVLTA HCL+   +P    V+LG    +   E  Q + V   +L +  S      D+AL
Sbjct: 387  CWVLTAAHCLQNRPAPEELTVVLGQDRHNQSCEWCQTLAVRSYRLHEGFSSITYQHDLAL 446

Query: 968  LKL-----SSPAVITDKVIPACLPTPNYVVADRTACYITGWG---ETKGTYGAGLLKEAR 1123
            L+L     +S A+++  V P CLP+     ++   C + GWG   E    Y    L+EA+
Sbjct: 447  LRLQESKTNSCAILSPHVQPVCLPSGAAPPSETVLCEVAGWGHQLEGAEEYST-FLQEAQ 505

Query: 1124 LPVIENKVCNRYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLVCFE---KDKYILQGV 1294
            +P I    C+     G  + P  LCAG L GG D+CQGDSGGPLVC E   + +  L+GV
Sbjct: 506  VPFIALDRCSNSNVHGDAILPGMLCAGFLEGGTDACQGDSGGPLVCEEGTAEHQLTLRGV 565

Query: 1295 TSWGLGCALPNKPGVYVRVXRFVTWIEE 1378
             SWG GC   NKPGVY  V  ++ WI++
Sbjct: 566  ISWGSGCGDRNKPGVYTDVANYLAWIQK 593



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 42/131 (32%), Positives = 63/131 (48%), Gaps = 18/131 (13%)
 Frame = +2

Query: 95  CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMN-YCRNPDADKSP 271
           CY G G SYRG + TT +G  CQ W     +R+  T     + GL  + +CRNPD D  P
Sbjct: 217 CYEGRGLSYRGQAGTTQSGAPCQRWTVEATYRN-MTEKQALSWGLGHHAFCRNPDNDTRP 275

Query: 272 WCYT-TDPRVRWEYCNLKKC-----------SETEQQVTNFPAIVQVPS-----VEDLSE 400
           WC+  +  R+ W+YC L++C              E+  +  P++   P+        LS+
Sbjct: 276 WCFVWSGDRLSWDYCGLEQCQTPTFAPLVVPESQEESPSQAPSLSHAPNDSTDHQTSLSK 335

Query: 401 DCMFGNGKRYR 433
               G G+R+R
Sbjct: 336 TNTMGCGQRFR 346


>ref|NP_542765.1| transmembrane protease, serine 3 [Mus musculus]
          Length = 453

 Score =  204 bits (518), Expect = 2e-52
 Identities = 106/238 (44%), Positives = 146/238 (61%), Gaps = 7/238 (2%)
 Frame = +2

Query: 701  RVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILG- 877
            R+VGG +S    WPWQ+SL+ + G H CGG++I+P W++TA HC+     P S+ V +G 
Sbjct: 216  RIVGGNMSSLTQWPWQVSLQFQ-GYHLCGGSIITPLWIVTAAHCVYDLYHPKSWTVQVGL 274

Query: 878  -----AHEEHHLGEGVQEIDVSKLFKEPSGADIALLKLSSPAVITDKVIPACLPTPNYVV 1042
                 +    HL E +  I  SK   +  G DIAL+KLS P    + + P CLP      
Sbjct: 275  VSLMDSPVPSHLVEKI--IYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPNSEENF 332

Query: 1043 ADRTACYITGWGETK-GTYGAGLLKEARLPVIENKVCNRYEYLGGKVSPNELCAGHLAGG 1219
             D   C+ +GWG T+ G   + +L  A +P+I NK+CN  +  GG +SP+ LCAG+L GG
Sbjct: 333  PDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLKGG 392

Query: 1220 IDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVXRFVTWIEEIMRRN 1393
            +DSCQGDSGGPLVC E+  + L G TS+G+GCA  NKPGVY R+  F+ WI E + R+
Sbjct: 393  VDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERD 450


>ref|NP_032307.1| hepsin [Mus musculus]
          Length = 416

 Score =  202 bits (515), Expect = 5e-52
 Identities = 127/330 (38%), Positives = 171/330 (51%), Gaps = 23/330 (6%)
 Frame = +2

Query: 452  VAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCD 631
            VAG+ C+E        HS     T    G    +C +  G            Q+L D   
Sbjct: 84   VAGLGCEEMGFLRALAHSELDVRTAGANGTSGFFCVDEGG--------LPLAQRLLDVIS 135

Query: 632  VPQCETSSF------DCGKPKMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGT 793
            V  C    F      DCG+ K+       R+VGG  S    WPWQ+SLR   G H CGG+
Sbjct: 136  VCDCPRGRFLTATCQDCGRRKLPVD----RIVGGQDSSLGRWPWQVSLRYD-GTHLCGGS 190

Query: 794  LISPEWVLTAKHCL-EKSSSPSSYKVILGA---HEEHHLGEGVQEIDVSK---LFKEPS- 949
            L+S +WVLTA HC  E++   S ++V  GA      H +  GVQ +        F++P+ 
Sbjct: 191  LLSGDWVLTAAHCFPERNRVLSRWRVFAGAVARTSPHAVQLGVQAVIYHGGYLPFRDPTI 250

Query: 950  ---GADIALLKLSSPAVITDKVIPACLPTPNYVVADRTACYITGWGETKGTYG--AGLLK 1114
                 DIAL+ LSS   +T+ + P CLP     + D   C +TGWG T+  YG  A +L+
Sbjct: 251  DENSNDIALVHLSSSLPLTEYIQPVCLPAAGQALVDGKVCTVTGWGNTQ-FYGQQAMVLQ 309

Query: 1115 EARLPVIENKVCNRYEYLGGKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEK----DKYI 1282
            EAR+P+I N+VCN  ++ G ++ P   CAG+  GGID+CQGDSGGP VC +      ++ 
Sbjct: 310  EARVPIISNEVCNSPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISGTSRWR 369

Query: 1283 LQGVTSWGLGCALPNKPGVYVRVXRFVTWI 1372
            L G+ SWG GCAL  KPGVY +V  F  WI
Sbjct: 370  LCGIVSWGTGCALARKPGVYTKVTDFREWI 399


>ref|NP_062320.1| hepatocyte growth factor activator [Mus musculus]
          Length = 653

 Score =  199 bits (507), Expect = 5e-51
 Identities = 127/372 (34%), Positives = 173/372 (46%), Gaps = 41/372 (11%)
 Frame = +2

Query: 395  SEDCMFGNGKRYRGKRATTVAGVPCQEWAA----QEPHRHSIFTPETNPRAGLEKN-YCR 559
            +E C  GNG  YRG  +T  +G+ C  W +    QE H  S+         GL  + YCR
Sbjct: 280  TEHCFLGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVAAAVL---LGLGPHAYCR 336

Query: 560  NPDGDDNGPWCYTTNPQKL-FDYCDVPQCETSSF---------------------DCGKP 673
            NPD D+  PWCY      L ++YC +  CE+ +                       CGK 
Sbjct: 337  NPDKDER-PWCYVVKDNALSWEYCRLTACESLARVHSQTPEILAALPESAPAVRPTCGKR 395

Query: 674  KMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEKSSSP 853
              +      R++GG  S+P S PW  ++    G  FC G+L+   WV++A HC   S   
Sbjct: 396  HKKRTFLRPRIIGGSSSLPGSHPWLAAIY--IGNSFCAGSLVHTCWVVSAAHCFANSPPR 453

Query: 854  SSYKVILGAHEEHHLGEGVQEIDVSKLFK-------EPSGADIALLKLSSP----AVITD 1000
             S  V+LG H  +   +  Q   + K           P+  D+ L++L       AV + 
Sbjct: 454  DSITVVLGQHFFNRTTDVTQTFGIEKYVPYTLYSVFNPNNHDLVLIRLKKKGERCAVRSQ 513

Query: 1001 KVIPACLPTPNYVVADRTACYITGWG---ETKGTYGAGLLKEARLPVIENKVCNRYEYLG 1171
             V P CLP           C I GWG   E   +Y   LL EA +P++ +  C+  E  G
Sbjct: 514  FVQPICLPEAGSSFPTGHKCQIAGWGHMDENVSSYSNSLL-EALVPLVADHKCSSPEVYG 572

Query: 1172 GKVSPNELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRV 1351
              +SPN LCAG+     D+CQGDSGGPLVC +     L G+ SWG GC   NKPGVY RV
Sbjct: 573  ADISPNMLCAGYFDCKSDACQGDSGGPLVCEKNGVAYLYGIISWGDGCGRLNKPGVYTRV 632

Query: 1352 XRFVTWIEEIMR 1387
              +V WI + +R
Sbjct: 633  ANYVDWINDRIR 644



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 36/98 (36%), Positives = 49/98 (50%), Gaps = 4/98 (4%)
 Frame = +2

Query: 89  QDCYRGNGESYRGTSSTTITGRKCQSWVS--MTPHRHEKTPGNFPNAGLTMN-YCRNPDA 259
           + C+ GNG  YRG +ST  +G  C +W S  +    H  +       GL  + YCRNPD 
Sbjct: 281 EHCFLGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVAAAVLLGLGPHAYCRNPDK 340

Query: 260 DKSPWCYTT-DPRVRWEYCNLKKCSETEQQVTNFPAIV 370
           D+ PWCY   D  + WEYC L  C    +  +  P I+
Sbjct: 341 DERPWCYVVKDNALSWEYCRLTACESLARVHSQTPEIL 378


>ref|NP_666213.1| hyaluronic acid binding protein 2 [Mus musculus]
          Length = 517

 Score =  199 bits (505), Expect = 8e-51
 Identities = 131/373 (35%), Positives = 184/373 (49%), Gaps = 42/373 (11%)
 Frame = +2

Query: 398  EDCMFGNGKRYRGKRATTVAGVPCQEWAAQE--PHRHSIFTPETNPRAGLEKNYCRNPDG 571
            +DC  G+G  YRGK + TV   PC  W +       +++F  +       E N+CRNPDG
Sbjct: 149  DDCYVGDGYSYRGKVSKTVNQNPCLYWNSHLLLQETYNMFMEDAETHGIAEHNFCRNPDG 208

Query: 572  DDNGPWCYT-TNPQKL-FDYCDVPQC-----------------ETSSFD-CGKPKMEPKK 691
            D   PWC+   N +K+ ++YCDV  C                 E   F+ CGK ++  + 
Sbjct: 209  DHK-PWCFVKVNSEKVKWEYCDVTVCPVPDTPNPVESLLEPVMELPGFESCGKTEVA-EH 266

Query: 692  CPARVVGGCVSIPHSWPWQISLRRRYG-------GHFCGGTLISPEWVLTAKHCLEKSSS 850
               R+ GG  S     PWQ+SL+           GHFCGG LI P WVLTA HC + ++ 
Sbjct: 267  AVKRIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGALIHPCWVLTAAHCTDINTK 326

Query: 851  PSSYKVILGAHEEHHLGEGVQEIDVSKLFK--------EPSGADIALLKLSSP----AVI 994
                KV+LG  +        Q   V K+ K        E    DIALLKL       A+ 
Sbjct: 327  --HLKVVLGDQDLKKTESHEQTFRVEKILKYSQYNERDEIPHNDIALLKLKPVGGHCALE 384

Query: 995  TDKVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLGG 1174
            +  V   CLP+  +     T C+I+GWG T+   G+  L +A++ +I N +CN  +    
Sbjct: 385  SRYVKTVCLPSDPF--PSGTECHISGWGVTETGEGSRQLLDAKVKLIANPLCNSRQLYDH 442

Query: 1175 KVSPNELCAGHLAG-GIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRV 1351
             +  + +CAG+L   G D+CQGDSGGPL C +   Y + G+ SWG  C    KPGVY +V
Sbjct: 443  TIDDSMICAGNLQKPGSDTCQGDSGGPLTCEKDGTYYVYGIVSWGQECG--KKPGVYTQV 500

Query: 1352 XRFVTWIEEIMRR 1390
             +F+ WI+  M R
Sbjct: 501  TKFLNWIKTTMHR 513



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 5/84 (5%)
 Frame = +2

Query: 92  DCYRGNGESYRGTSSTTITGRKCQSWVS--MTPHRHEKTPGNFPNAGLTM-NYCRNPDAD 262
           DCY G+G SYRG  S T+    C  W S  +    +     +    G+   N+CRNPD D
Sbjct: 150 DCYVGDGYSYRGKVSKTVNQNPCLYWNSHLLLQETYNMFMEDAETHGIAEHNFCRNPDGD 209

Query: 263 KSPWCY--TTDPRVRWEYCNLKKC 328
             PWC+      +V+WEYC++  C
Sbjct: 210 HKPWCFVKVNSEKVKWEYCDVTVC 233


>ref|XP_926294.1| PREDICTED: similar to protease, serine, 33 isoform 5 [Mus musculus]
          Length = 293

 Score =  195 bits (495), Expect = 1e-49
 Identities = 102/256 (39%), Positives = 144/256 (56%), Gaps = 18/256 (7%)
 Frame = +2

Query: 662  CGKPKMEPKKCPARVVGGCVSIPHSWPWQISLRRRYGGHFCGGTLISPEWVLTAKHCLEK 841
            CG+P+M      +R+VGG  +    WPWQ S++ R G H CGG+LI+P+WVLTA HC  +
Sbjct: 41   CGQPRMS-----SRIVGGRDAQDGEWPWQTSIQHR-GAHVCGGSLIAPQWVLTAGHCFPR 94

Query: 842  SSSPSSYKVILGA-----HEEHHLGEGVQEIDVSKLFKEPSG-ADIALLKLSSPAVITDK 1003
               PS Y V+LGA        H L   V  + +   + E     D+ALL+L  P  ++ +
Sbjct: 95   RVWPSEYSVLLGALSLDVRSSHELLVPVLRVLLPPDYSEDEARGDLALLQLRHPVSLSTR 154

Query: 1004 VIPACLPTPNYVVADRTACYITGWGETKGTYGAGL-----LKEARLPVIENKVCNRYEYL 1168
            + P CLP P       + C++TGWG      G  L     L+  R+P+++++ C+R  ++
Sbjct: 155  IQPVCLPAPGSHPPPGSPCWVTGWGSLSP--GVPLPKGRPLQGVRVPLLDSRACDRLYHV 212

Query: 1169 GGKVS-------PNELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPN 1327
            G  V        P  LCAG+  G  D+CQGDSGGPL C E   ++L GV SWG GCALPN
Sbjct: 213  GANVPQGERIVLPGNLCAGYRRGHKDACQGDSGGPLTCMESGHWVLVGVVSWGKGCALPN 272

Query: 1328 KPGVYVRVXRFVTWIE 1375
            +PGVY  V ++  WI+
Sbjct: 273  RPGVYTNVAKYSPWIQ 288


  Database: RefSeqMP
    Posted date:  Aug 2, 2006 12:58 AM
  Number of letters in database: 21,768,885
  Number of sequences in database:  45,328
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,780,147
Number of Sequences: 45328
Number of extensions: 2395436
Number of successful extensions: 10711
Number of sequences better than 1.0e-05: 10
Number of HSP's better than  0.0 without gapping: 7240
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9872
length of database: 21,768,885
effective HSP length: 107
effective length of database: 16,918,789
effective search space used: 6192276774
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)