BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-005279
(1411 letters)
Database: RefSeqSP
1040 sequences; 434,620 total letters
Searching...done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_999497.1| G-beta like protein [Sus scrofa] 659 0.0
Alignment gi|NP_999415.1| platelet-activating factor acetylhydrolase Ib-a... 130 8e-32
Alignment gi|NP_001012296.1| fizzy/cell division cycle 20 related 1 [Sus ... 64 1e-11
>ref|NP_999497.1| G-beta like protein [Sus scrofa]
Length = 317
Score = 659 bits (1701), Expect = 0.0
Identities = 316/317 (99%), Positives = 316/317 (99%)
Frame = +2
Query: 383 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 562
MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 563 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 742
GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 743 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 922
VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 923 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC 1102
NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC 240
Query: 1103 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 1282
FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA
Sbjct: 241 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1283 GYTDNLVRVWQVTIGPR 1333
GYTDNLVRVWQVTIG R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
>ref|NP_999415.1| platelet-activating factor acetylhydrolase Ib-alpha subunit [Sus
scrofa]
Length = 410
Score = 130 bits (327), Expect = 8e-32
Identities = 98/324 (30%), Positives = 141/324 (43%), Gaps = 23/324 (7%)
Frame = +2
Query: 413 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 592
L GH VT++ P F M+ SAS D TI +W + G +R L+GH+ V D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVQDIS 157
Query: 593 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 772
G+ S S D T++LWD R GH +V SVA + IVS +RDKTIK
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSAARDKTIK 217
Query: 773 LWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 949
+W G C T H EWV VR PN +I SC D+ V+VW +A + K
Sbjct: 218 MWEVQTGYCVKTF--TGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 273
Query: 950 GHTGYLNTVTVSPD--------------------GSLCASGGKDGQAMLWDLNEGKHLYT 1069
H + ++ +P+ G SG +D +WD++ G L T
Sbjct: 274 EHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMT 333
Query: 1070 LDGGD--IINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCT 1243
L G D + L S ++ L A ++++WD + K + L A T
Sbjct: 334 LVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTL---------NAHEHFVT 384
Query: 1244 SLAWSADGQTLFAGYTDNLVRVWQ 1315
SL + + G D V+VW+
Sbjct: 385 SLDFHKTAPYVVTGSVDQTVKVWE 408
>ref|NP_001012296.1| fizzy/cell division cycle 20 related 1 [Sus scrofa]
Length = 493
Score = 63.5 bits (153), Expect = 1e-11
Identities = 69/289 (23%), Positives = 119/289 (41%), Gaps = 7/289 (2%)
Frame = +2
Query: 473 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 652
+LS + +W + + ++ G S V+ V S G G+ G +++W
Sbjct: 200 VLSVGLGTCVYLWSACTSQVTR-LCDLSVEGDS--VTSVGWSERGNLVAVGTHKGFVQIW 256
Query: 653 DLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDE----S 820
D G GHT V ++A+++D Q+ SGSRD+ I + +Q E
Sbjct: 257 DAAAGKKLSMLEGHTARVGALAWNAD--QLSSGSRDRMIL---QRDIRTPPLQSERRLQG 311
Query: 821 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 997
H + V +++S + + ++ S G D + VWN ++ + H + + SP
Sbjct: 312 HRQEVCGLKWS--TDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHG 369
Query: 998 LCASGG--KDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEG 1171
L ASGG D W+ G+ L +D G + L +S + L + G S +
Sbjct: 370 LLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYS------QN 423
Query: 1172 KIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 1318
+I+V + + LA S DG+ + G D +R W V
Sbjct: 424 QILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
Score = 61.6 bits (148), Expect = 4e-11
Identities = 51/219 (23%), Positives = 94/219 (42%), Gaps = 8/219 (3%)
Frame = +2
Query: 413 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 592
L+GH V +A D + S SRD+ I+ + +R L+GH V +
Sbjct: 267 LEGHTARVGALAWNA---DQLSSGSRDRMILQRDIRTPPLQ---SERRLQGHRQEVCGLK 320
Query: 593 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS---GSRDK 763
S+D Q SG D L +W+ ++ + +++ H V ++A+S +++ G+ D+
Sbjct: 321 WSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADR 380
Query: 764 TIKLWNTLG----VCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDK-LVKVWNLANC 928
I+ WNTL C T + W +N ++ + G+ + + VW +
Sbjct: 381 CIRFWNTLTGQPLQCIDTGSQVCNLAW-------SKHANELVSTHGYSQNQILVWKYPSL 433
Query: 929 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL 1045
GH+ + + +SPDG +G D W++
Sbjct: 434 TQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
Database: RefSeqSP
Posted date: Aug 1, 2006 7:14 PM
Number of letters in database: 434,620
Number of sequences in database: 1040
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,434,169
Number of Sequences: 1040
Number of extensions: 39559
Number of successful extensions: 154
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 120
length of database: 434,620
effective HSP length: 80
effective length of database: 351,420
effective search space used: 136702380
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqBP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-005279
(1411 letters)
Database: RefSeqBP
33,508 sequences; 16,112,626 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_786996.1| guanine nucleotide binding protein (G protein),... 659 0.0
Alignment gi|XP_589608.2| PREDICTED: similar to Guanine nucleotide-bindin... 414 e-116
Alignment gi|XP_881436.1| PREDICTED: similar to Guanine nucleotide-bindin... 221 1e-57
Alignment gi|NP_777088.1| platelet-activating factor acetylhydrolase, iso... 131 1e-30
Alignment gi|XP_603483.2| PREDICTED: similar to WD repeat domain 51B [Bos... 114 1e-25
Alignment gi|XP_591008.2| PREDICTED: similar to guanine nucleotide-bindin... 112 7e-25
Alignment gi|NP_001033649.1| WD repeat domain 51A [Bos taurus] 107 2e-23
Alignment gi|XP_603152.1| PREDICTED: similar to TAF5-like RNA polymerase ... 107 2e-23
Alignment gi|NP_001014887.1| Notchless gene homolog [Bos taurus] 104 1e-22
Alignment gi|XP_594126.2| PREDICTED: similar to TBP-associated factor 5 [... 104 2e-22
>ref|NP_786996.1| guanine nucleotide binding protein (G protein), beta polypeptide
2-like 1 [Bos taurus]
Length = 317
Score = 659 bits (1701), Expect = 0.0
Identities = 316/317 (99%), Positives = 316/317 (99%)
Frame = +2
Query: 383 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 562
MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 563 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 742
GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 743 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 922
VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 923 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC 1102
NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC 240
Query: 1103 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 1282
FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA
Sbjct: 241 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1283 GYTDNLVRVWQVTIGPR 1333
GYTDNLVRVWQVTIG R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
>ref|XP_589608.2| PREDICTED: similar to Guanine nucleotide-binding protein beta subunit
2-like 1 (Receptor of activated protein kinase C 1)
(RACK1) (Receptor for activated C kinase) isoform 1 [Bos
taurus]
Length = 228
Score = 414 bits (1065), Expect = e-116
Identities = 195/198 (98%), Positives = 196/198 (98%)
Frame = +2
Query: 740 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 919
I+S SRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL
Sbjct: 31 ILSASRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 90
Query: 920 ANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINAL 1099
ANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINAL
Sbjct: 91 ANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINAL 150
Query: 1100 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 1279
CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF
Sbjct: 151 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 210
Query: 1280 AGYTDNLVRVWQVTIGPR 1333
AGYTDNLVRVWQVTIG R
Sbjct: 211 AGYTDNLVRVWQVTIGTR 228
Score = 124 bits (310), Expect = 2e-28
Identities = 85/233 (36%), Positives = 115/233 (49%), Gaps = 9/233 (3%)
Frame = +2
Query: 383 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 562
MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTI +W T Y + +
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIKLWN-TLGVCKYTVQDES-- 57
Query: 563 GHSHFVSDVVIS--SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 736
HS +VS V S S +S WD +++W+L +GHT + +V S D
Sbjct: 58 -HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGS 116
Query: 737 QIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPN------SSNPIIVSCGWD 895
SG +D LW+ G YT+ + ++ + FSPN ++ P I +
Sbjct: 117 LCASGGKDGQAMLWDLNEGKHLYTLDG---GDIINALCFSPNRYWLCAATGPSIKIWDLE 173
Query: 896 KLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 1054
+ V L + T+ ++ S DG +G D +W + G
Sbjct: 174 GKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 226
>ref|XP_881436.1| PREDICTED: similar to Guanine nucleotide-binding protein beta subunit
2-like 1 (Receptor of activated protein kinase C 1)
(RACK1) (Receptor for activated C kinase) isoform 2 [Bos
taurus]
Length = 126
Score = 221 bits (563), Expect = 1e-57
Identities = 104/106 (98%), Positives = 105/106 (99%)
Frame = +2
Query: 1016 KDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELK 1195
+DGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELK
Sbjct: 21 QDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELK 80
Query: 1196 QEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGPR 1333
QEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG R
Sbjct: 81 QEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR 126
>ref|NP_777088.1| platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit
(45kD) [Bos taurus]
Length = 410
Score = 131 bits (330), Expect = 1e-30
Identities = 99/324 (30%), Positives = 141/324 (43%), Gaps = 23/324 (7%)
Frame = +2
Query: 413 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 592
L GH VT++ P F M+ SAS D TI +W + G +R L+GH+ V D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVEDIS 157
Query: 593 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 772
G+ S S D T++LWD R GH +V SVA + IVS SRDKTIK
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 217
Query: 773 LWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 949
+W G C T H EWV VR PN +I SC D+ V+VW +A + K
Sbjct: 218 MWEVQTGYCVKTF--TGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 273
Query: 950 GHTGYLNTVTVSPD--------------------GSLCASGGKDGQAMLWDLNEGKHLYT 1069
H + ++ +P+ G SG +D +WD++ G L T
Sbjct: 274 EHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMT 333
Query: 1070 LDGGD--IINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCT 1243
L G D + L S ++ L A ++++WD + K + L A T
Sbjct: 334 LVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTL---------NAHEHFVT 384
Query: 1244 SLAWSADGQTLFAGYTDNLVRVWQ 1315
SL + + G D V+VW+
Sbjct: 385 SLDFHKTAPYVVTGSVDQTVKVWE 408
>ref|XP_603483.2| PREDICTED: similar to WD repeat domain 51B [Bos taurus]
Length = 495
Score = 114 bits (286), Expect = 1e-25
Identities = 84/302 (27%), Positives = 133/302 (44%), Gaps = 46/302 (15%)
Frame = +2
Query: 548 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 727
+R +GH ++ V S +G+ +GSWD L LW L R+VGH + SV FS
Sbjct: 28 ERYFKGHKAAITSVDFSPNGKQLATGSWDTFLMLWSLRPQARAFRYVGHKDVITSVQFSP 87
Query: 728 DNRQIVSGSRDKTIKLW-------------NTLGV-----------CKYTVQDES----- 820
+ S SRD+TI+LW +T V +D+S
Sbjct: 88 LGNLLASASRDRTIRLWIPDKRGKSSEFKAHTAPVRSVDFSADGQFLASASEDKSIKVWN 147
Query: 821 ------------HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGY 964
H+ WV C +FSP+ +IVSC DK +K+W+ N + N G+
Sbjct: 148 MYRQRFLYSLYRHTHWVRCAKFSPDGR--LIVSCSEDKTIKIWDTTNKQCVNNFSDFVGF 205
Query: 965 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGK---HLYTLDGGDIINALCFSPN-RYWLCA 1132
N V +P+G+ AS G D +WD+ K H GG +N + F P+ Y + A
Sbjct: 206 ANFVAFNPNGTCIASAGSDHTVKIWDIRVNKLLQHYQVHSGG--VNCVSFHPSGNYLITA 263
Query: 1133 ATGPSIKIWD-LEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRV 1309
++ ++KI D LEG++I + + ++++S G+ +G D V +
Sbjct: 264 SSDGTLKILDLLEGRLIY----------TLQGHTGPVFTVSFSKGGELFTSGGADAQVLL 313
Query: 1310 WQ 1315
W+
Sbjct: 314 WR 315
Score = 110 bits (275), Expect = 3e-24
Identities = 76/226 (33%), Positives = 114/226 (50%), Gaps = 6/226 (2%)
Frame = +2
Query: 419 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-----LRGHSHFVS 583
GH +T + +P +++ SASRD+TI +W IP + + H+ V
Sbjct: 75 GHKDVITSVQFSP-LGNLLASASRDRTIRLW----------IPDKRGKSSEFKAHTAPVR 123
Query: 584 DVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDK 763
V S+DGQF S S D ++++W++ HT V FS D R IVS S DK
Sbjct: 124 SVDFSADGQFLASASEDKSIKVWNMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDK 183
Query: 764 TIKLWNTLGVCKYTVQDESHSE-WVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 940
TIK+W+T K V + S + + V F+PN + I S G D VK+W++ KL
Sbjct: 184 TIKIWDTTN--KQCVNNFSDFVGFANFVAFNPNGT--CIASAGSDHTVKIWDIRVNKLLQ 239
Query: 941 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 1078
++ H+G +N V+ P G+ + DG + DL EG+ +YTL G
Sbjct: 240 HYQVHSGGVNCVSFHPSGNYLITASSDGTLKILDLLEGRLIYTLQG 285
Score = 98.6 bits (244), Expect = 1e-20
Identities = 63/192 (32%), Positives = 95/192 (49%)
Frame = +2
Query: 473 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 652
+ SAS DK+I +W + R Y +L H+H+V S DG+ +S S D T+++W
Sbjct: 134 LASASEDKSIKVWNMYRQRFLY-----SLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 188
Query: 653 DLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEW 832
D T F VAF+ + I S D T+K+W+ + V K + HS
Sbjct: 189 DTTNKQCVNNFSDFVGFANFVAFNPNGTCIASAGSDHTVKIWD-IRVNKLLQHYQVHSGG 247
Query: 833 VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASG 1012
V+CV F P+ + +++ D +K+ +L +L GHTG + TV+ S G L SG
Sbjct: 248 VNCVSFHPSGN--YLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFTSG 305
Query: 1013 GKDGQAMLWDLN 1048
G D Q +LW N
Sbjct: 306 GADAQVLLWRTN 317
Score = 72.8 bits (177), Expect = 6e-13
Identities = 52/218 (23%), Positives = 99/218 (45%), Gaps = 2/218 (0%)
Frame = +2
Query: 677 RRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSP 856
R F GH + SV FS + +Q+ +GS D + LW+ + + H + ++ V+FSP
Sbjct: 29 RYFKGHKAAITSVDFSPNGKQLATGSWDTFLMLWSLRPQAR-AFRYVGHKDVITSVQFSP 87
Query: 857 NSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAML 1036
+ ++ S D+ +++W + HT + +V S DG AS +D +
Sbjct: 88 LGN--LLASASRDRTIRLWIPDKRGKSSEFKAHTAPVRSVDFSADGQFLASASEDKSIKV 145
Query: 1037 WDLNEGKHLYTL-DGGDIINALCFSPN-RYWLCAATGPSIKIWDLEGKIIVDELKQEVIS 1210
W++ + LY+L + FSP+ R + + +IKIWD K V+ V
Sbjct: 146 WNMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDFV-- 203
Query: 1211 TSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTI 1324
+A++ +G + + +D+ V++W + +
Sbjct: 204 -------GFANFVAFNPNGTCIASAGSDHTVKIWDIRV 234
>ref|XP_591008.2| PREDICTED: similar to guanine nucleotide-binding protein, beta-3
subunit [Bos taurus]
Length = 333
Score = 112 bits (280), Expect = 7e-25
Identities = 79/260 (30%), Positives = 127/260 (48%), Gaps = 5/260 (1%)
Frame = +2
Query: 548 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 727
+R LRGH + + ++D + +S S DG L +WD T + V++ A++
Sbjct: 48 RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 728 DNRQIVSGSRDKTIKLWNTL---GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDK 898
+ G D +++ G K + + +H+ ++SC RF + N I+ S G D
Sbjct: 108 SGNFVACGGLDNMCSIYSLKSREGNVKVSRELSAHTGYLSCCRFLDD--NNIVTSSG-DT 164
Query: 899 LVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 1078
+W++ + KT +GHTG ++ VSPD L SG D A LWD+ EG T G
Sbjct: 165 TCALWDIETGQQKTVFVGHTGDCMSLAVSPDFRLFISGACDASAKLWDVREGTCRQTFTG 224
Query: 1079 GDI-INALCFSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLA 1252
+ INA+CF PN +C + S +++DL QE+ + + ++ TS+A
Sbjct: 225 HESDINAICFFPNGEAICTGSDDASCRLFDLRAD-------QELTTYAHESIICGITSVA 277
Query: 1253 WSADGQTLFAGYTDNLVRVW 1312
+S G+ LFAGY D VW
Sbjct: 278 FSLSGRLLFAGYDDFNCNVW 297
Score = 72.0 bits (175), Expect = 1e-12
Identities = 64/223 (28%), Positives = 98/223 (43%), Gaps = 3/223 (1%)
Frame = +2
Query: 425 NGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD 604
+ WV A P + + D ++ L E N + R L H+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNMCSIYSLKSREGNVKV-SRELSAHTGYLSCCRFLDD 154
Query: 605 GQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT 784
S S D T LWD+ TG FVGHT D +S+A S D R +SG+ D + KLW+
Sbjct: 155 NNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFRLFISGACDASAKLWDV 213
Query: 785 L-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKT-NHIGH 955
G C+ T H ++ + F PN I + D ++++L A+ +L T H
Sbjct: 214 REGTCRQTF--TGHESDINAICFFPNGE--AICTGSDDASCRLFDLRADQELTTYAHESI 269
Query: 956 TGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 1084
+ +V S G L +G D +WD + + + L G D
Sbjct: 270 ICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKCERVGILSGHD 312
>ref|NP_001033649.1| WD repeat domain 51A [Bos taurus]
Length = 407
Score = 107 bits (267), Expect = 2e-23
Identities = 81/301 (26%), Positives = 129/301 (42%), Gaps = 45/301 (14%)
Frame = +2
Query: 548 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 727
+R +GH V+ V S + + SGS D L +W + T RF GH V V FS
Sbjct: 12 ERHFKGHRDAVTSVDFSLNTKQLASGSMDSCLMVWHMKPQTRAYRFAGHKDAVTCVNFSP 71
Query: 728 DNRQIVSGSRDKTIKLW------------------NTLGVC------------------- 796
+ SGSRDKT+++W ++ C
Sbjct: 72 SGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWS 131
Query: 797 ----KYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGY 964
K+ H WV C +FSP+ +IVS DK VK+W+ + + ++ H G+
Sbjct: 132 THRQKFLFSLSQHINWVRCAKFSPDGR--LIVSASDDKTVKLWDKTSRECVHSYCEHGGF 189
Query: 965 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHL--YTLDGGDIINALCFSPN-RYWLCAA 1135
+ V P G+ A+ G D +WD+ + L Y L +NAL F P+ Y + A+
Sbjct: 190 VTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSA-AVNALSFHPSGNYLVTAS 248
Query: 1136 TGPSIKIWDL-EGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVW 1312
+ ++KI DL EG+++ + T++A+S G+ +G +D V VW
Sbjct: 249 SDSTLKILDLMEGRLLY----------TLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
Query: 1313 Q 1315
+
Sbjct: 299 K 299
Score = 102 bits (254), Expect = 7e-22
Identities = 79/301 (26%), Positives = 116/301 (38%), Gaps = 44/301 (14%)
Frame = +2
Query: 389 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGH 568
E +L KGH VT + + + S S D +++W + Y GH
Sbjct: 7 EDPSLERHFKGHRDAVTSVDFSLN-TKQLASGSMDSCLMVWHMKPQTRAY-----RFAGH 60
Query: 569 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 748
V+ V S G SGS D T+R+W + F HT V SV F SD + V+
Sbjct: 61 KDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVT 120
Query: 749 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 928
S DKT+K+W+T K+ H WV C +FSP+ +IVS DK VK+W+ +
Sbjct: 121 ASDDKTVKVWSTHRQ-KFLFSLSQHINWVRCAKFSPDGR--LIVSASDDKTVKLWDKTSR 177
Query: 929 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWD---------------------- 1042
+ ++ H G++ V P G+ A+ G D +WD
Sbjct: 178 ECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNALSF 237
Query: 1043 --------------------LNEGKHLYTLDG--GDIINALCFSPNRYWLCAATGPSIKI 1156
L EG+ LYTL G G Y+ + + +
Sbjct: 238 HPSGNYLVTASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMV 297
Query: 1157 W 1159
W
Sbjct: 298 W 298
Score = 84.0 bits (206), Expect = 3e-16
Identities = 56/191 (29%), Positives = 89/191 (46%)
Frame = +2
Query: 476 LSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWD 655
++AS DKT+ +W R + + + Q H ++V S DG+ +S S D T++LWD
Sbjct: 119 VTASDDKTVKVWSTHRQKFLFSLSQ-----HINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
Query: 656 LTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWV 835
T+ + H V V F I + D T+K+W+ + + + HS V
Sbjct: 174 KTSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD-VRTHRLLQHYQLHSAAV 232
Query: 836 SCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGG 1015
+ + F P+ + +V+ D +K+ +L +L GH G TV S G ASGG
Sbjct: 233 NALSFHPSGN--YLVTASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGG 290
Query: 1016 KDGQAMLWDLN 1048
D Q M+W N
Sbjct: 291 SDEQVMVWKSN 301
>ref|XP_603152.1| PREDICTED: similar to TAF5-like RNA polymerase II p300/CBP-associated
factor-associated factor 65 kDa subunit 5L
(PCAF-associated factor 65 beta) (PAF65-beta) [Bos
taurus]
Length = 600
Score = 107 bits (267), Expect = 2e-23
Identities = 79/230 (34%), Positives = 109/230 (47%), Gaps = 3/230 (1%)
Frame = +2
Query: 398 TLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHF 577
T R L GH G V P +LS S D +I W L TN + Q GH++
Sbjct: 344 TERKVLLGHCGPVYSTRFLPD-SSALLSCSEDTSIRYWDL-ESFTNTVLYQ----GHAYP 397
Query: 578 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 757
V D+ IS F S S+D T RLW R + GH V V F ++ + +GS
Sbjct: 398 VWDLDISPHSLFFASASYDHTARLWSFDRTYPLRIYAGHLAGVDCVKFHPNSNYLATGST 457
Query: 758 DKTIKLWNTL---GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 928
DKT++LW+ V +T H V C+ FSPN +VS G D+L+K+W+LA+
Sbjct: 458 DKTVRLWSAQQGNSVRLFT----GHCGPVRCLAFSPNGQ--YLVSAGEDQLLKLWDLASG 511
Query: 929 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 1078
L + GHT + +VT S D S+ AS D +WD+ + DG
Sbjct: 512 TLYKDLHGHTDDITSVTFSLDSSVIASASMDNSVRIWDIKSKHNSTPADG 561
Score = 87.8 bits (216), Expect = 2e-17
Identities = 64/219 (29%), Positives = 97/219 (44%), Gaps = 2/219 (0%)
Frame = +2
Query: 524 DETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKD 703
+E ++ L GH V D LS S D ++R WDL + T T + GH
Sbjct: 338 EEDRTATERKVLLGHCGPVYSTRFLPDSSALLSCSEDTSIRYWDLESFTNTVLYQGHAYP 397
Query: 704 VLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVS 883
V + S + S S D T +LW+ + H V CV+F PNS+ + +
Sbjct: 398 VWDLDISPHSLFFASASYDHTARLWSFDRTYPLRIY-AGHLAGVDCVKFHPNSN--YLAT 454
Query: 884 CGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHL 1063
DK V++W+ GH G + + SP+G S G+D LWDL G
Sbjct: 455 GSTDKTVRLWSAQQGNSVRLFTGHCGPVRCLAFSPNGQYLVSAGEDQLLKLWDLASGTLY 514
Query: 1064 YTLDG-GDIINALCFSPNRYWLCAAT-GPSIKIWDLEGK 1174
L G D I ++ FS + + +A+ S++IWD++ K
Sbjct: 515 KDLHGHTDDITSVTFSLDSSVIASASMDNSVRIWDIKSK 553
Score = 76.6 bits (187), Expect = 4e-14
Identities = 56/221 (25%), Positives = 93/221 (42%), Gaps = 2/221 (0%)
Frame = +2
Query: 662 TGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSC 841
T T + +GH V S F D+ ++S S D +I+ W+ L TV + H+ V
Sbjct: 342 TATERKVLLGHCGPVYSTRFLPDSSALLSCSEDTSIRYWD-LESFTNTVLYQGHAYPVWD 400
Query: 842 VRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKD 1021
+ SP+S S +D ++W+ + GH ++ V P+ + A+G D
Sbjct: 401 LDISPHSL--FFASASYDHTARLWSFDRTYPLRIYAGHLAGVDCVKFHPNSNYLATGSTD 458
Query: 1022 GQAMLWDLNEGKHLYTLDGG-DIINALCFSPN-RYWLCAATGPSIKIWDLEGKIIVDELK 1195
LW +G + G + L FSPN +Y + A +K+WDL + +L
Sbjct: 459 KTVRLWSAQQGNSVRLFTGHCGPVRCLAFSPNGQYLVSAGEDQLLKLWDLASGTLYKDLH 518
Query: 1196 QEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 1318
TS+ +S D + + DN VR+W +
Sbjct: 519 ---------GHTDDITSVTFSLDSSVIASASMDNSVRIWDI 550
Score = 76.3 bits (186), Expect = 6e-14
Identities = 53/174 (30%), Positives = 80/174 (45%), Gaps = 8/174 (4%)
Frame = +2
Query: 479 SASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDL 658
SAS D T +W R P R GH V V + + +GS D T+RLW
Sbjct: 412 SASYDHTARLWSFDRT-----YPLRIYAGHLAGVDCVKFHPNSNYLATGSTDKTVRLWSA 466
Query: 659 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 838
G + R F GH V +AFS + + +VS D+ +KLW+ Y H++ ++
Sbjct: 467 QQGNSVRLFTGHCGPVRCLAFSPNGQYLVSAGEDQLLKLWDLASGTLYK-DLHGHTDDIT 525
Query: 839 CVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG--------HTGYLNTV 976
V FS +SS +I S D V++W++ + T G +TG ++TV
Sbjct: 526 SVTFSLDSS--VIASASMDNSVRIWDIKSKHNSTPADGSSSELLGVYTGQMSTV 577
Score = 73.6 bits (179), Expect = 4e-13
Identities = 45/137 (32%), Positives = 66/137 (48%)
Frame = +2
Query: 419 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 598
GH V + P + + + S DKT+ +W + G R GH V + S
Sbjct: 435 GHLAGVDCVKFHPN-SNYLATGSTDKTVRLWSAQQ-----GNSVRLFTGHCGPVRCLAFS 488
Query: 599 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 778
+GQ+ +S D L+LWDL +GT + GHT D+ SV FS D+ I S S D ++++W
Sbjct: 489 PNGQYLVSAGEDQLLKLWDLASGTLYKDLHGHTDDITSVTFSLDSSVIASASMDNSVRIW 548
Query: 779 NTLGVCKYTVQDESHSE 829
+ T D S SE
Sbjct: 549 DIKSKHNSTPADGSSSE 565
Score = 57.0 bits (136), Expect = 4e-08
Identities = 59/247 (23%), Positives = 103/247 (41%), Gaps = 3/247 (1%)
Frame = +2
Query: 596 SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 775
S D + +G + +++LW LT+ ++ H DV + +D ++ R T +
Sbjct: 291 SPDNKLLATGLNNSSIKLWSLTSKFKSKP---HQIDVSHIHLINDTLEVDEEDRTATERK 347
Query: 776 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 955
LG C V RF P+SS ++SC D ++ W+L + + GH
Sbjct: 348 V-LLGHCGP----------VYSTRFLPDSS--ALLSCSEDTSIRYWDLESFTNTVLYQGH 394
Query: 956 TGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC--FSPNRYWLC 1129
+ + +SP AS D A LW + L + G + C F PN +L
Sbjct: 395 AYPVWDLDISPHSLFFASASYDHTARLWSFDRTYPL-RIYAGHLAGVDCVKFHPNSNYLA 453
Query: 1130 A-ATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVR 1306
+T ++++W + V + P +C LA+S +GQ L + D L++
Sbjct: 454 TGSTDKTVRLWSAQQG-------NSVRLFTGHCGPVRC--LAFSPNGQYLVSAGEDQLLK 504
Query: 1307 VWQVTIG 1327
+W + G
Sbjct: 505 LWDLASG 511
>ref|NP_001014887.1| Notchless gene homolog [Bos taurus]
Length = 486
Score = 104 bits (260), Expect = 1e-22
Identities = 95/356 (26%), Positives = 158/356 (44%), Gaps = 53/356 (14%)
Frame = +2
Query: 410 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 589
+L+GH+ V +A +P + S S D T+ W L+ + P +GH H+V +
Sbjct: 110 SLEGHSEAVISVAFSPT-GKYLASGSGDTTVRFWDLSTET-----PHFTCQGHRHWVLSI 163
Query: 590 VISSDGQFALSGSWDGTLRLWDLTTGTTT-RRFVGHTKDVLSVAF-----SSDNRQIVSG 751
S DG+ SG +G + LWD +TG R GH+K + ++++ + + R + S
Sbjct: 164 SWSPDGKKLASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHANPECRYVASS 223
Query: 752 SRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 928
S+D ++++W+ T G C+ T+ H++ V+C+R+ + ++ S D+ +KVW +
Sbjct: 224 SKDGSVRVWDTTAGRCERTL--TGHAQSVTCLRW---GGDGLLYSASQDRTIKVWRAHDG 278
Query: 929 KLKTNHIGHTGYLNTVTVSPD---------------------GSL--------------- 1000
L GH ++NT+ +S D GSL
Sbjct: 279 VLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNAQDLRGSLQELKERALSRYNLVR 338
Query: 1001 ------CASGGKDGQAMLWDLNEGKH-LYTLDGGD-IINALCFSP-NRYWLCAATGPSIK 1153
SG D LW E K L + G +IN + FSP +R A+ SIK
Sbjct: 339 GQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVVFSPDSRVIASASFDKSIK 398
Query: 1154 IWD-LEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 1318
+WD GK + S + +AWSAD + L +G +D+ ++VW V
Sbjct: 399 LWDGRTGKYL----------ASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDV 444
Score = 104 bits (259), Expect = 2e-22
Identities = 87/351 (24%), Positives = 149/351 (42%), Gaps = 49/351 (13%)
Frame = +2
Query: 410 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 589
T +GH WV I+ +P + S ++ I++W D + RAL GHS +++ +
Sbjct: 152 TCQGHRHWVLSISWSPD-GKKLASGCKNGQILLW----DPSTGKQVGRALTGHSKWITAL 206
Query: 590 V-----ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGS 754
+ + ++ S S DG++R+WD T G R GH + V + + D + S S
Sbjct: 207 SWEPLHANPECRYVASSSKDGSVRVWDTTAGRCERTLTGHAQSVTCLRWGGDGL-LYSAS 265
Query: 755 RDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPN------------------------ 859
+D+TIK+W GV T+Q H WV+ + S +
Sbjct: 266 QDRTIKVWRAHDGVLCRTLQ--GHGHWVNTMALSTDYALRTGAFEPAEASVNAQDLRGSL 323
Query: 860 --------SSNPIIVSCGWDKLVK--------VWNLANCKLKTNHI-GHTGYLNTVTVSP 988
S ++ G ++LV +W+ A K + GH +N V SP
Sbjct: 324 QELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVVFSP 383
Query: 989 DGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFSPNRYWLCAATGPSIKIWD 1162
D + AS D LWD GK+L +L G + + +R + ++ ++K+WD
Sbjct: 384 DSRVIASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWD 443
Query: 1163 LEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQ 1315
+ K + +ST + ++ WS DGQ + +G D +R+W+
Sbjct: 444 V---------KAQKLSTDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 485
Score = 67.0 bits (162), Expect = 3e-11
Identities = 58/196 (29%), Positives = 87/196 (44%), Gaps = 11/196 (5%)
Frame = +2
Query: 773 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI- 949
++ V + T E HSE V V FSP + + S D V+ W+L+ +T H
Sbjct: 98 IFRVRAVTRCTSSLEGHSEAVISVAFSP--TGKYLASGSGDTTVRFWDLST---ETPHFT 152
Query: 950 --GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHL-YTLDG-GDIINALCFSP-- 1111
GH ++ +++ SPDG ASG K+GQ +LWD + GK + L G I AL + P
Sbjct: 153 CQGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLH 212
Query: 1112 ----NRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 1279
RY ++ S+++WD L S T L W DG L+
Sbjct: 213 ANPECRYVASSSKDGSVRVWDTTAGRCERTLTGHAQSV---------TCLRWGGDG-LLY 262
Query: 1280 AGYTDNLVRVWQVTIG 1327
+ D ++VW+ G
Sbjct: 263 SASQDRTIKVWRAHDG 278
Score = 60.1 bits (144), Expect = 4e-09
Identities = 44/170 (25%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Frame = +2
Query: 674 TRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRF 850
T GH++ V+SVAFS + + SGS D T++ W+ + +T Q H WV + +
Sbjct: 108 TSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCQ--GHRHWVLSISW 165
Query: 851 SPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI-GHTGYLNTVT-----VSPDGSLCASG 1012
SP+ + S + + +W+ + K + GH+ ++ ++ +P+ AS
Sbjct: 166 SPDGKK--LASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHANPECRYVASS 223
Query: 1013 GKDGQAMLWDLNEGKHLYTLDG-GDIINALCFSPNRYWLCAATGPSIKIW 1159
KDG +WD G+ TL G + L + + A+ +IK+W
Sbjct: 224 SKDGSVRVWDTTAGRCERTLTGHAQSVTCLRWGGDGLLYSASQDRTIKVW 273
>ref|XP_594126.2| PREDICTED: similar to TBP-associated factor 5 [Bos taurus]
Length = 800
Score = 104 bits (259), Expect = 2e-22
Identities = 67/206 (32%), Positives = 102/206 (49%), Gaps = 2/206 (0%)
Frame = +2
Query: 551 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 730
+ L GHS V S D + LS S DGT+RLW L T T + GH V FS
Sbjct: 537 KILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPY 596
Query: 731 NRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKV 910
VSG D+ +LW T + H V+C RF PNS+ + + D+ V++
Sbjct: 597 GYYFVSGGHDRVARLWATDHYQPLRI-FAGHLADVNCTRFHPNSN--YVATGSADRTVRL 653
Query: 911 WNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDI 1087
W++ N GH G ++++T SP+G A+G DG+ +LWD+ G + L G D
Sbjct: 654 WDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDT 713
Query: 1088 INALCFSPNRYWLCAAT-GPSIKIWD 1162
+ +L FS + L + + ++++WD
Sbjct: 714 VCSLRFSRDGEILASGSMDNTVRLWD 739
Score = 90.9 bits (224), Expect = 2e-18
Identities = 67/226 (29%), Positives = 105/226 (46%), Gaps = 3/226 (1%)
Frame = +2
Query: 644 RLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESH 823
R+ D T + + GH+ V +FS D ++S S D T++LW +L V + H
Sbjct: 526 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLW-SLQTFTCLVGYKGH 584
Query: 824 SEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLC 1003
+ V +FSP VS G D++ ++W + + GH +N P+ +
Sbjct: 585 NYPVWDTQFSPYGY--YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYV 642
Query: 1004 ASGGKDGQAMLWDLNEGK--HLYTLDGGDIINALCFSPN-RYWLCAATGPSIKIWDLEGK 1174
A+G D LWD+ G ++T G I++L FSPN R+ AT + +WD+
Sbjct: 643 ATGSADRTVRLWDVLNGNCVRIFTGHKGP-IHSLTFSPNGRFLATGATDGRVLLWDIGHG 701
Query: 1175 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVW 1312
++V EL K SL +S DG+ L +G DN VR+W
Sbjct: 702 LMVGEL---------KGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 70.9 bits (172), Expect = 2e-12
Identities = 48/169 (28%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 416 KGHNG--WVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 589
KGHN W TQ + + +S D+ +W T++ P R GH V+
Sbjct: 582 KGHNYPVWDTQFSPYGYY---FVSGGHDRVARLWA-----TDHYQPLRIFAGHLADVNCT 633
Query: 590 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 769
+ + +GS D T+RLWD+ G R F GH + S+ FS + R + +G+ D +
Sbjct: 634 RFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRV 693
Query: 770 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 916
LW+ +G + + H++ V +RFS + I+ S D V++W+
Sbjct: 694 LLWD-IGHGLMVGELKGHTDTVCSLRFSRDGE--ILASGSMDNTVRLWD 739
Score = 66.6 bits (161), Expect = 4e-11
Identities = 33/105 (31%), Positives = 53/105 (50%)
Frame = +2
Query: 473 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 652
+ + S D+T+ +W + G R GH + + S +G+F +G+ DG + LW
Sbjct: 642 VATGSADRTVRLWDVLN-----GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLW 696
Query: 653 DLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL 787
D+ G GHT V S+ FS D + SGS D T++LW+ +
Sbjct: 697 DIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAV 741
Database: RefSeqBP
Posted date: Aug 1, 2006 7:14 PM
Number of letters in database: 16,112,626
Number of sequences in database: 33,508
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,192,265
Number of Sequences: 33508
Number of extensions: 1504536
Number of successful extensions: 8042
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 4518
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6540
length of database: 16,112,626
effective HSP length: 105
effective length of database: 12,594,286
effective search space used: 4584320104
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqCP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-005279
(1411 letters)
Database: RefSeqCP
33,732 sequences; 19,266,565 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|XP_537934.2| PREDICTED: similar to Guanine nucleotide-bindin... 650 0.0
Alignment gi|XP_855850.1| PREDICTED: similar to Guanine nucleotide-bindin... 619 e-177
Alignment gi|XP_855931.1| PREDICTED: similar to Guanine nucleotide-bindin... 561 e-160
Alignment gi|XP_855887.1| PREDICTED: similar to Guanine nucleotide-bindin... 213 5e-55
Alignment gi|XP_537775.2| PREDICTED: similar to platelet-activating facto... 131 1e-30
Alignment gi|XP_854482.1| PREDICTED: similar to platelet-activating facto... 131 1e-30
Alignment gi|XP_868508.1| PREDICTED: similar to platelet-activating facto... 131 1e-30
Alignment gi|XP_868519.1| PREDICTED: similar to platelet-activating facto... 129 5e-30
Alignment gi|XP_541857.2| PREDICTED: similar to WD repeat domain 51A isof... 128 2e-29
Alignment gi|XP_859995.1| PREDICTED: similar to WD repeat domain 51A isof... 115 8e-26
>ref|XP_537934.2| PREDICTED: similar to Guanine nucleotide-binding protein beta subunit
2-like 1 (Receptor of activated protein kinase C 1)
(RACK1) (Receptor for activated C kinase) isoform 1
[Canis familiaris]
Length = 316
Score = 650 bits (1677), Expect = 0.0
Identities = 314/317 (99%), Positives = 314/317 (99%)
Frame = +2
Query: 383 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 562
MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 563 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 742
GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 743 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 922
VSGSRDKTIKLWNTLGVCKYTVQ SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQG-SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 179
Query: 923 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC 1102
NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC
Sbjct: 180 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC 239
Query: 1103 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 1282
FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA
Sbjct: 240 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 299
Query: 1283 GYTDNLVRVWQVTIGPR 1333
GYTDNLVRVWQVTIG R
Sbjct: 300 GYTDNLVRVWQVTIGTR 316
>ref|XP_855850.1| PREDICTED: similar to Guanine nucleotide-binding protein beta subunit
2-like 1 (Receptor of activated protein kinase C 1)
(RACK1) (Receptor for activated C kinase) isoform 3
[Canis familiaris]
Length = 302
Score = 619 bits (1596), Expect = e-177
Identities = 296/296 (100%), Positives = 296/296 (100%)
Frame = +2
Query: 383 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 562
MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 563 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 742
GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 743 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 922
VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 923 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC 1102
NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC 240
Query: 1103 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQ 1270
FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQ
Sbjct: 241 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQ 296
>ref|XP_855931.1| PREDICTED: similar to Guanine nucleotide-binding protein beta subunit
2-like 1 (Receptor of activated protein kinase C 1)
(RACK1) (Receptor for activated C kinase) isoform 5
[Canis familiaris]
Length = 280
Score = 561 bits (1447), Expect = e-160
Identities = 279/317 (88%), Positives = 279/317 (88%)
Frame = +2
Query: 383 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 562
MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 563 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 742
GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 743 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 922
VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV------ 174
Query: 923 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC 1102
KDGQAMLWDLNEGKHLYTLDGGDIINALC
Sbjct: 175 -------------------------------KDGQAMLWDLNEGKHLYTLDGGDIINALC 203
Query: 1103 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 1282
FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA
Sbjct: 204 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 263
Query: 1283 GYTDNLVRVWQVTIGPR 1333
GYTDNLVRVWQVTIG R
Sbjct: 264 GYTDNLVRVWQVTIGTR 280
>ref|XP_855887.1| PREDICTED: similar to Guanine nucleotide-binding protein beta subunit
2-like 1 (Receptor of activated protein kinase C 1)
(RACK1) (Receptor for activated C kinase) isoform 4
[Canis familiaris]
Length = 101
Score = 213 bits (541), Expect = 5e-55
Identities = 100/101 (99%), Positives = 100/101 (99%)
Frame = +2
Query: 1031 MLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVIS 1210
MLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVIS
Sbjct: 1 MLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVIS 60
Query: 1211 TSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGPR 1333
TSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG R
Sbjct: 61 TSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR 101
>ref|XP_537775.2| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
subunit isoform 1 [Canis familiaris]
Length = 372
Score = 131 bits (330), Expect = 1e-30
Identities = 99/324 (30%), Positives = 141/324 (43%), Gaps = 23/324 (7%)
Frame = +2
Query: 413 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 592
L GH VT++ P F M+ SAS D TI +W + G +R L+GH+ V D+
Sbjct: 66 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVQDIS 119
Query: 593 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 772
G+ S S D T++LWD R GH +V SVA + IVS SRDKTIK
Sbjct: 120 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 179
Query: 773 LWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 949
+W G C T H EWV VR PN +I SC D+ V+VW +A + K
Sbjct: 180 MWEVQTGYCVKTF--TGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 235
Query: 950 GHTGYLNTVTVSPD--------------------GSLCASGGKDGQAMLWDLNEGKHLYT 1069
H + ++ +P+ G SG +D +WD++ G L T
Sbjct: 236 EHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMT 295
Query: 1070 LDGGD--IINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCT 1243
L G D + L S ++ L A ++++WD + K + L A T
Sbjct: 296 LVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTL---------NAHEHFVT 346
Query: 1244 SLAWSADGQTLFAGYTDNLVRVWQ 1315
SL + + G D V+VW+
Sbjct: 347 SLDFHKTAPYVVTGSVDQTVKVWE 370
>ref|XP_854482.1| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
subunit isoform 2 [Canis familiaris]
Length = 410
Score = 131 bits (330), Expect = 1e-30
Identities = 99/324 (30%), Positives = 141/324 (43%), Gaps = 23/324 (7%)
Frame = +2
Query: 413 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 592
L GH VT++ P F M+ SAS D TI +W + G +R L+GH+ V D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVQDIS 157
Query: 593 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 772
G+ S S D T++LWD R GH +V SVA + IVS SRDKTIK
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 217
Query: 773 LWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 949
+W G C T H EWV VR PN +I SC D+ V+VW +A + K
Sbjct: 218 MWEVQTGYCVKTF--TGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 273
Query: 950 GHTGYLNTVTVSPD--------------------GSLCASGGKDGQAMLWDLNEGKHLYT 1069
H + ++ +P+ G SG +D +WD++ G L T
Sbjct: 274 EHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMT 333
Query: 1070 LDGGD--IINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCT 1243
L G D + L S ++ L A ++++WD + K + L A T
Sbjct: 334 LVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTL---------NAHEHFVT 384
Query: 1244 SLAWSADGQTLFAGYTDNLVRVWQ 1315
SL + + G D V+VW+
Sbjct: 385 SLDFHKTAPYVVTGSVDQTVKVWE 408
>ref|XP_868508.1| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
subunit isoform 3 [Canis familiaris]
Length = 345
Score = 131 bits (330), Expect = 1e-30
Identities = 99/324 (30%), Positives = 141/324 (43%), Gaps = 23/324 (7%)
Frame = +2
Query: 413 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 592
L GH VT++ P F M+ SAS D TI +W + G +R L+GH+ V D+
Sbjct: 39 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVQDIS 92
Query: 593 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 772
G+ S S D T++LWD R GH +V SVA + IVS SRDKTIK
Sbjct: 93 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 152
Query: 773 LWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 949
+W G C T H EWV VR PN +I SC D+ V+VW +A + K
Sbjct: 153 MWEVQTGYCVKTF--TGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 208
Query: 950 GHTGYLNTVTVSPD--------------------GSLCASGGKDGQAMLWDLNEGKHLYT 1069
H + ++ +P+ G SG +D +WD++ G L T
Sbjct: 209 EHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMT 268
Query: 1070 LDGGD--IINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCT 1243
L G D + L S ++ L A ++++WD + K + L A T
Sbjct: 269 LVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTL---------NAHEHFVT 319
Query: 1244 SLAWSADGQTLFAGYTDNLVRVWQ 1315
SL + + G D V+VW+
Sbjct: 320 SLDFHKTAPYVVTGSVDQTVKVWE 343
>ref|XP_868519.1| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
subunit isoform 5 [Canis familiaris]
Length = 415
Score = 129 bits (325), Expect = 5e-30
Identities = 99/329 (30%), Positives = 141/329 (42%), Gaps = 28/329 (8%)
Frame = +2
Query: 413 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 592
L GH VT++ P F M+ SAS D TI +W + G +R L+GH+ V D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVQDIS 157
Query: 593 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 772
G+ S S D T++LWD R GH +V SVA + IVS SRDKTIK
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 217
Query: 773 LWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 949
+W G C T H EWV VR PN +I SC D+ V+VW +A + K
Sbjct: 218 MWEVQTGYCVKTF--TGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 273
Query: 950 GHTGYLNTVTVSPD-------------------------GSLCASGGKDGQAMLWDLNEG 1054
H + ++ +P+ G SG +D +WD++ G
Sbjct: 274 EHEHVVECISWAPESSYSSISEATGSEEENPRTKKSGKPGPFLLSGSRDKTIKMWDVSTG 333
Query: 1055 KHLYTLDGGD--IINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAE 1228
L TL G D + L S ++ L A ++++WD + K + L A
Sbjct: 334 MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTL---------NAH 384
Query: 1229 PPQCTSLAWSADGQTLFAGYTDNLVRVWQ 1315
TSL + + G D V+VW+
Sbjct: 385 EHFVTSLDFHKTAPYVVTGSVDQTVKVWE 413
>ref|XP_541857.2| PREDICTED: similar to WD repeat domain 51A isoform 1 [Canis
familiaris]
Length = 406
Score = 128 bits (321), Expect = 2e-29
Identities = 93/313 (29%), Positives = 145/313 (46%), Gaps = 4/313 (1%)
Frame = +2
Query: 389 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGH 568
E +L KGH +T + + + S S D +++W + Y GH
Sbjct: 7 EDPSLERHFKGHRDAITSVDFSLN-TKQLASGSMDSCLMVWHMKPQSRAY-----RFAGH 60
Query: 569 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 748
V+ V S G SGS D T+R+W + F HT V SV F SD + +V+
Sbjct: 61 KDAVTCVNFSPSGHLLASGSRDKTVRIWIPNVKGESTVFRAHTATVRSVHFCSDGQSLVT 120
Query: 749 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 928
S DKT+K+W+T K+ H WV C RFSP+ +IVS DK VK+W+ +
Sbjct: 121 ASDDKTVKVWSTHRQ-KFLFSLSQHINWVRCARFSPDGR--LIVSASDDKTVKLWDKTSR 177
Query: 929 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHL--YTLDGGDIINALC 1102
+ ++ H G++ V P G+ A+ D +WD+ + L Y L +NAL
Sbjct: 178 ECVHSYCEHGGFVTYVDFHPSGTCIAAASMDNTVKVWDVRTHRLLQHYQLHSA-AVNALS 236
Query: 1103 FSPN-RYWLCAATGPSIKIWDL-EGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTL 1276
F P+ Y L A++ ++KI DL EG+++ + T++A+S G+
Sbjct: 237 FHPSGNYLLTASSDSTLKILDLMEGRLLY----------TLHGHQGPATTVAFSRTGEYF 286
Query: 1277 FAGYTDNLVRVWQ 1315
+G +D V VW+
Sbjct: 287 ASGGSDEQVMVWK 299
Score = 84.7 bits (208), Expect = 2e-16
Identities = 56/192 (29%), Positives = 91/192 (47%)
Frame = +2
Query: 473 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 652
+++AS DKT+ +W R + + + Q H ++V S DG+ +S S D T++LW
Sbjct: 118 LVTASDDKTVKVWSTHRQKFLFSLSQ-----HINWVRCARFSPDGRLIVSASDDKTVKLW 172
Query: 653 DLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEW 832
D T+ + H V V F I + S D T+K+W+ + + + HS
Sbjct: 173 DKTSRECVHSYCEHGGFVTYVDFHPSGTCIAAASMDNTVKVWD-VRTHRLLQHYQLHSAA 231
Query: 833 VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASG 1012
V+ + F P+ + +++ D +K+ +L +L GH G TV S G ASG
Sbjct: 232 VNALSFHPSGN--YLLTASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASG 289
Query: 1013 GKDGQAMLWDLN 1048
G D Q M+W N
Sbjct: 290 GSDEQVMVWKSN 301
Score = 50.8 bits (120), Expect = 3e-06
Identities = 35/121 (28%), Positives = 54/121 (44%)
Frame = +2
Query: 422 HNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISS 601
H G+VT + P I +AS D T+ +W D + + Q + HS V+ +
Sbjct: 186 HGGFVTYVDFHPS-GTCIAAASMDNTVKVW----DVRTHRLLQH-YQLHSAAVNALSFHP 239
Query: 602 DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 781
G + L+ S D TL++ DL G GH +VAFS SG D+ + +W
Sbjct: 240 SGNYLLTASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 299
Query: 782 T 784
+
Sbjct: 300 S 300
>ref|XP_859995.1| PREDICTED: similar to WD repeat domain 51A isoform 2 [Canis
familiaris]
Length = 388
Score = 115 bits (289), Expect = 8e-26
Identities = 88/311 (28%), Positives = 139/311 (44%), Gaps = 2/311 (0%)
Frame = +2
Query: 389 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGH 568
E +L KGH +T + + + S S D +++W + Y GH
Sbjct: 7 EDPSLERHFKGHRDAITSVDFSLN-TKQLASGSMDSCLMVWHMKPQSRAY-----RFAGH 60
Query: 569 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 748
V+ V S G SGS D T+R+W + F HT V SV F SD + +V+
Sbjct: 61 KDAVTCVNFSPSGHLLASGSRDKTVRIWIPNVKGESTVFRAHTATVRSVHFCSDGQSLVT 120
Query: 749 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 928
S DKT+K+W+T K+ H WV C RFSP+ +IVS DK VK+W+ +
Sbjct: 121 ASDDKTVKVWSTHRQ-KFLFSLSQHINWVRCARFSPDGR--LIVSASDDKTVKLWDKTSR 177
Query: 929 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 1108
+ ++ H G++ V P G+ +S G + + +NAL F
Sbjct: 178 ECVHSYCEHGGFVTYVDFHPSGTCISSSGVNVHSA-----------------AVNALSFH 220
Query: 1109 PN-RYWLCAATGPSIKIWDL-EGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 1282
P+ Y L A++ ++KI DL EG+++ + T++A+S G+ +
Sbjct: 221 PSGNYLLTASSDSTLKILDLMEGRLLY----------TLHGHQGPATTVAFSRTGEYFAS 270
Query: 1283 GYTDNLVRVWQ 1315
G +D V VW+
Sbjct: 271 GGSDEQVMVWK 281
Score = 84.7 bits (208), Expect = 2e-16
Identities = 68/233 (29%), Positives = 95/233 (40%), Gaps = 23/233 (9%)
Frame = +2
Query: 419 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 598
GH VT + +P ++ S SRDKT+ +W N R H+ V V
Sbjct: 59 GHKDAVTCVNFSPS-GHLLASGSRDKTVRIWI-----PNVKGESTVFRAHTATVRSVHFC 112
Query: 599 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 778
SDGQ ++ S D T+++W H V FS D R IVS S DKT+KLW
Sbjct: 113 SDGQSLVTASDDKTVKVWSTHRQKFLFSLSQHINWVRCARFSPDGRLIVSASDDKTVKLW 172
Query: 779 NTL-----------------------GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCG 889
+ G C + HS V+ + F P+ + +++
Sbjct: 173 DKTSRECVHSYCEHGGFVTYVDFHPSGTCISSSGVNVHSAAVNALSFHPSGN--YLLTAS 230
Query: 890 WDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 1048
D +K+ +L +L GH G TV S G ASGG D Q M+W N
Sbjct: 231 SDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN 283
Score = 52.4 bits (124), Expect = 1e-06
Identities = 38/144 (26%), Positives = 57/144 (39%), Gaps = 19/144 (13%)
Frame = +2
Query: 410 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYG---------------- 541
+L H WV +P +I+SAS DKT+ +W T E +
Sbjct: 140 SLSQHINWVRCARFSPD-GRLIVSASDDKTVKLWDKTSRECVHSYCEHGGFVTYVDFHPS 198
Query: 542 ---IPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS 712
I + HS V+ + G + L+ S D TL++ DL G GH +
Sbjct: 199 GTCISSSGVNVHSAAVNALSFHPSGNYLLTASSDSTLKILDLMEGRLLYTLHGHQGPATT 258
Query: 713 VAFSSDNRQIVSGSRDKTIKLWNT 784
VAFS SG D+ + +W +
Sbjct: 259 VAFSRTGEYFASGGSDEQVMVWKS 282
Database: RefSeqCP
Posted date: Aug 1, 2006 9:25 PM
Number of letters in database: 19,266,565
Number of sequences in database: 33,732
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,303,189
Number of Sequences: 33732
Number of extensions: 1760341
Number of successful extensions: 9136
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 5124
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7355
length of database: 19,266,565
effective HSP length: 107
effective length of database: 15,657,241
effective search space used: 5667921242
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqHP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-005279
(1411 letters)
Database: RefSeqHP
39,411 sequences; 17,774,539 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_006089.1| guanine nucleotide binding protein (G protein),... 659 0.0
Alignment gi|XP_931937.1| PREDICTED: similar to Guanine nucleotide-bindin... 294 1e-79
Alignment gi|XP_941915.1| PREDICTED: similar to Guanine nucleotide-bindin... 294 1e-79
Alignment gi|NP_000421.1| platelet-activating factor acetylhydrolase, iso... 131 1e-30
Alignment gi|NP_438172.1| WD repeat domain 5 [Homo sapiens] 123 3e-28
Alignment gi|NP_060058.1| WD repeat domain 5 [Homo sapiens] 123 3e-28
Alignment gi|NP_061942.2| WD repeat domain 5B [Homo sapiens] 122 7e-28
Alignment gi|NP_002066.1| guanine nucleotide-binding protein, beta-3 subu... 117 3e-26
Alignment gi|NP_758440.1| WD repeat domain 51B [Homo sapiens] 112 8e-25
Alignment gi|XP_947007.1| PREDICTED: similar to CG7704-PA isoform 1 [Homo... 112 1e-24
>ref|NP_006089.1| guanine nucleotide binding protein (G protein), beta polypeptide
2-like 1 [Homo sapiens]
Length = 317
Score = 659 bits (1701), Expect = 0.0
Identities = 316/317 (99%), Positives = 316/317 (99%)
Frame = +2
Query: 383 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 562
MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 563 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 742
GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 743 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 922
VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 923 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC 1102
NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC 240
Query: 1103 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 1282
FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA
Sbjct: 241 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1283 GYTDNLVRVWQVTIGPR 1333
GYTDNLVRVWQVTIG R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
>ref|XP_931937.1| PREDICTED: similar to Guanine nucleotide-binding protein beta subunit
2-like 1 (Receptor of activated protein kinase C 1)
(RACK1) (Receptor for activated C kinase) [Homo sapiens]
Length = 162
Score = 294 bits (752), Expect = 1e-79
Identities = 140/160 (87%), Positives = 143/160 (89%)
Frame = +2
Query: 824 SEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLC 1003
+EWVSCVRF PNSSNPI VSC WDKLVKVWNLANCKLKTNHIGHTGYLNTVT+SP+GSLC
Sbjct: 4 TEWVSCVRFLPNSSNPITVSCSWDKLVKVWNLANCKLKTNHIGHTGYLNTVTMSPNGSLC 63
Query: 1004 ASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIV 1183
ASGGKDGQAMLWDLNEGKHLY DGG IIN LCFSPN YWLCAA GPSIKIWDL IIV
Sbjct: 64 ASGGKDGQAMLWDLNEGKHLYMPDGGGIINTLCFSPNCYWLCAAMGPSIKIWDLGVNIIV 123
Query: 1184 DELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLV 1303
DELKQEVIST SKAEPPQCTSLAWS G LFAGYTDNLV
Sbjct: 124 DELKQEVISTGSKAEPPQCTSLAWSVGGH-LFAGYTDNLV 162
>ref|XP_941915.1| PREDICTED: similar to Guanine nucleotide-binding protein beta subunit
2-like 1 (Receptor of activated protein kinase C 1)
(RACK1) (Receptor for activated C kinase) [Homo sapiens]
Length = 162
Score = 294 bits (752), Expect = 1e-79
Identities = 140/160 (87%), Positives = 143/160 (89%)
Frame = +2
Query: 824 SEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLC 1003
+EWVSCVRF PNSSNPI VSC WDKLVKVWNLANCKLKTNHIGHTGYLNTVT+SP+GSLC
Sbjct: 4 TEWVSCVRFLPNSSNPITVSCSWDKLVKVWNLANCKLKTNHIGHTGYLNTVTMSPNGSLC 63
Query: 1004 ASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIV 1183
ASGGKDGQAMLWDLNEGKHLY DGG IIN LCFSPN YWLCAA GPSIKIWDL IIV
Sbjct: 64 ASGGKDGQAMLWDLNEGKHLYMPDGGGIINTLCFSPNCYWLCAAMGPSIKIWDLGVNIIV 123
Query: 1184 DELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLV 1303
DELKQEVIST SKAEPPQCTSLAWS G LFAGYTDNLV
Sbjct: 124 DELKQEVISTGSKAEPPQCTSLAWSVGGH-LFAGYTDNLV 162
>ref|NP_000421.1| platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit
(45kD) [Homo sapiens]
Length = 410
Score = 131 bits (330), Expect = 1e-30
Identities = 99/324 (30%), Positives = 141/324 (43%), Gaps = 23/324 (7%)
Frame = +2
Query: 413 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 592
L GH VT++ P F M+ SAS D TI +W + G +R L+GH+ V D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVQDIS 157
Query: 593 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 772
G+ S S D T++LWD R GH +V SVA + IVS SRDKTIK
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 217
Query: 773 LWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 949
+W G C T H EWV VR PN +I SC D+ V+VW +A + K
Sbjct: 218 MWEVQTGYCVKTF--TGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 273
Query: 950 GHTGYLNTVTVSPD--------------------GSLCASGGKDGQAMLWDLNEGKHLYT 1069
H + ++ +P+ G SG +D +WD++ G L T
Sbjct: 274 EHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMT 333
Query: 1070 LDGGD--IINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCT 1243
L G D + L S ++ L A ++++WD + K + L A T
Sbjct: 334 LVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTL---------NAHEHFVT 384
Query: 1244 SLAWSADGQTLFAGYTDNLVRVWQ 1315
SL + + G D V+VW+
Sbjct: 385 SLDFHKTAPYVVTGSVDQTVKVWE 408
>ref|NP_438172.1| WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 123 bits (309), Expect = 3e-28
Identities = 89/275 (32%), Positives = 141/275 (51%), Gaps = 6/275 (2%)
Frame = +2
Query: 512 KLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVG 691
K T + NY + + L GH+ VS V S +G++ S S D +++W G + G
Sbjct: 27 KPTPVKPNYAL-KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISG 85
Query: 692 HTKDVLSVAFSSDNRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSN 868
H + VA+SSD+ +VS S DKT+K+W+ + G C T++ HS +V C F+P S+
Sbjct: 86 HKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK--GHSNYVFCCNFNPQSN- 142
Query: 869 PIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 1048
+IVS +D+ V++W++ K H+ ++ V + DGSL S DG +WD
Sbjct: 143 -LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA 201
Query: 1049 EGKHLYTL--DGGDIINALCFSPN-RYWLCAATGPSIKIWDL-EGKIIVDELKQEVISTS 1216
G+ L TL D ++ + FSPN +Y L A ++K+WD +GK + T
Sbjct: 202 SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTY-------TG 254
Query: 1217 SKAEPPQCTSLAWSADG-QTLFAGYTDNLVRVWQV 1318
K E C +S G + + +G DNLV +W +
Sbjct: 255 HKNEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNL 288
Score = 112 bits (281), Expect = 6e-25
Identities = 86/282 (30%), Positives = 141/282 (50%), Gaps = 10/282 (3%)
Frame = +2
Query: 401 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 580
L+ TL GH V+ + +P + + S+S DK I +W G ++ + GH +
Sbjct: 37 LKFTLAGHTKAVSSVKFSPN-GEWLASSSADKLIKIWGAYD-----GKFEKTISGHKLGI 90
Query: 581 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRD 760
SDV SSD +S S D TL++WD+++G + GH+ V F+ + IVSGS D
Sbjct: 91 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 150
Query: 761 KTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCK-L 934
+++++W+ G C T+ +HS+ VS V F N +IVS +D L ++W+ A+ + L
Sbjct: 151 ESVRIWDVKTGKCLKTL--PAHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDTASGQCL 206
Query: 935 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD-----IINAL 1099
KT ++ V SP+G + D LWD ++GK L T G I
Sbjct: 207 KTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANF 266
Query: 1100 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELK---QEVISTS 1216
+ ++ + + + IW+L+ K IV +L+ VIST+
Sbjct: 267 SVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTA 308
Score = 86.7 bits (213), Expect = 4e-17
Identities = 63/214 (29%), Positives = 100/214 (46%), Gaps = 4/214 (1%)
Frame = +2
Query: 410 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 589
TLKGH+ +V PQ ++I+S S D+++ +W + G + L HS VS V
Sbjct: 124 TLKGHSNYVFCCNFNPQ-SNLIVSGSFDESVRIW-----DVKTGKCLKTLPAHSDPVSAV 177
Query: 590 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDKT 766
+ DG +S S+DG R+WD +G + + +S V FS + + I++ + D T
Sbjct: 178 HFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNT 237
Query: 767 IKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTN 943
+KLW+ + G C T + ++ FS IVS D LV +WNL ++
Sbjct: 238 LKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK-WIVSGSEDNLVYIWNLQTKEIVQK 296
Query: 944 HIGHTGYLNTVTVSPDGSLCASGG--KDGQAMLW 1039
GHT + + P ++ AS D LW
Sbjct: 297 LQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 68.6 bits (166), Expect = 1e-11
Identities = 48/172 (27%), Positives = 80/172 (46%), Gaps = 3/172 (1%)
Frame = +2
Query: 821 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSL 1000
H++ VS V+FSPN + S DKL+K+W + K + GH ++ V S D +L
Sbjct: 44 HTKAVSSVKFSPNGE--WLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNL 101
Query: 1001 CASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC-FSPNRYWLCAAT-GPSIKIWDLE-G 1171
S D +WD++ GK L TL G C F+P + + + S++IWD++ G
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTG 161
Query: 1172 KIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 1327
K + + A +++ ++ DG + + D L R+W G
Sbjct: 162 KCL----------KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG 203
>ref|NP_060058.1| WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 123 bits (309), Expect = 3e-28
Identities = 89/275 (32%), Positives = 141/275 (51%), Gaps = 6/275 (2%)
Frame = +2
Query: 512 KLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVG 691
K T + NY + + L GH+ VS V S +G++ S S D +++W G + G
Sbjct: 27 KPTPVKPNYAL-KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISG 85
Query: 692 HTKDVLSVAFSSDNRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSN 868
H + VA+SSD+ +VS S DKT+K+W+ + G C T++ HS +V C F+P S+
Sbjct: 86 HKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK--GHSNYVFCCNFNPQSN- 142
Query: 869 PIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 1048
+IVS +D+ V++W++ K H+ ++ V + DGSL S DG +WD
Sbjct: 143 -LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA 201
Query: 1049 EGKHLYTL--DGGDIINALCFSPN-RYWLCAATGPSIKIWDL-EGKIIVDELKQEVISTS 1216
G+ L TL D ++ + FSPN +Y L A ++K+WD +GK + T
Sbjct: 202 SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTY-------TG 254
Query: 1217 SKAEPPQCTSLAWSADG-QTLFAGYTDNLVRVWQV 1318
K E C +S G + + +G DNLV +W +
Sbjct: 255 HKNEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNL 288
Score = 112 bits (281), Expect = 6e-25
Identities = 86/282 (30%), Positives = 141/282 (50%), Gaps = 10/282 (3%)
Frame = +2
Query: 401 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 580
L+ TL GH V+ + +P + + S+S DK I +W G ++ + GH +
Sbjct: 37 LKFTLAGHTKAVSSVKFSPN-GEWLASSSADKLIKIWGAYD-----GKFEKTISGHKLGI 90
Query: 581 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRD 760
SDV SSD +S S D TL++WD+++G + GH+ V F+ + IVSGS D
Sbjct: 91 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 150
Query: 761 KTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCK-L 934
+++++W+ G C T+ +HS+ VS V F N +IVS +D L ++W+ A+ + L
Sbjct: 151 ESVRIWDVKTGKCLKTL--PAHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDTASGQCL 206
Query: 935 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD-----IINAL 1099
KT ++ V SP+G + D LWD ++GK L T G I
Sbjct: 207 KTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANF 266
Query: 1100 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELK---QEVISTS 1216
+ ++ + + + IW+L+ K IV +L+ VIST+
Sbjct: 267 SVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTA 308
Score = 86.7 bits (213), Expect = 4e-17
Identities = 63/214 (29%), Positives = 100/214 (46%), Gaps = 4/214 (1%)
Frame = +2
Query: 410 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 589
TLKGH+ +V PQ ++I+S S D+++ +W + G + L HS VS V
Sbjct: 124 TLKGHSNYVFCCNFNPQ-SNLIVSGSFDESVRIW-----DVKTGKCLKTLPAHSDPVSAV 177
Query: 590 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDKT 766
+ DG +S S+DG R+WD +G + + +S V FS + + I++ + D T
Sbjct: 178 HFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNT 237
Query: 767 IKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTN 943
+KLW+ + G C T + ++ FS IVS D LV +WNL ++
Sbjct: 238 LKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK-WIVSGSEDNLVYIWNLQTKEIVQK 296
Query: 944 HIGHTGYLNTVTVSPDGSLCASGG--KDGQAMLW 1039
GHT + + P ++ AS D LW
Sbjct: 297 LQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 68.6 bits (166), Expect = 1e-11
Identities = 48/172 (27%), Positives = 80/172 (46%), Gaps = 3/172 (1%)
Frame = +2
Query: 821 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSL 1000
H++ VS V+FSPN + S DKL+K+W + K + GH ++ V S D +L
Sbjct: 44 HTKAVSSVKFSPNGE--WLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNL 101
Query: 1001 CASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC-FSPNRYWLCAAT-GPSIKIWDLE-G 1171
S D +WD++ GK L TL G C F+P + + + S++IWD++ G
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTG 161
Query: 1172 KIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 1327
K + + A +++ ++ DG + + D L R+W G
Sbjct: 162 KCL----------KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG 203
>ref|NP_061942.2| WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 122 bits (306), Expect = 7e-28
Identities = 91/289 (31%), Positives = 146/289 (50%), Gaps = 6/289 (2%)
Frame = +2
Query: 470 MILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRL 649
+ LS+S +++ K + NY + + L GH+ VS V S +G++ S S D + +
Sbjct: 13 LALSSSANQS----KEVPENPNYAL-KCTLVGHTEAVSSVKFSPNGEWLASSSADRLIII 67
Query: 650 WDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDESHS 826
W G + GH ++ VA+SSD+ ++VS S DKT+KLW+ G C T++ HS
Sbjct: 68 WGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLK--GHS 125
Query: 827 EWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCA 1006
+V C F+P S+ +I+S +D+ VK+W + K H+ ++ V + GSL
Sbjct: 126 NYVFCCNFNPPSN--LIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIV 183
Query: 1007 SGGKDGQAMLWDLNEGKHLYTL--DGGDIINALCFSPN-RYWLCAATGPSIKIWDLE-GK 1174
SG DG +WD G+ L TL D ++ + FSPN +Y L A ++K+WD G+
Sbjct: 184 SGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGR 243
Query: 1175 IIVDELKQEVISTSSKAEPPQCTSLAWSADG-QTLFAGYTDNLVRVWQV 1318
+ T K E C +S G + + +G DNLV +W +
Sbjct: 244 CLKTY-------TGHKNEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNL 284
Score = 114 bits (285), Expect = 2e-25
Identities = 85/272 (31%), Positives = 136/272 (50%), Gaps = 7/272 (2%)
Frame = +2
Query: 401 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 580
L+ TL GH V+ + +P + + S+S D+ II+W G ++ L GH+ +
Sbjct: 33 LKCTLVGHTEAVSSVKFSPN-GEWLASSSADRLIIIWGAYD-----GKYEKTLYGHNLEI 86
Query: 581 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRD 760
SDV SSD +S S D TL+LWD+ +G + GH+ V F+ + I+SGS D
Sbjct: 87 SDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFD 146
Query: 761 KTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCK-L 934
+T+K+W G C T+ +HS+ VS V F N S +IVS +D L ++W+ A+ + L
Sbjct: 147 ETVKIWEVKTGKCLKTL--SAHSDPVSAVHF--NCSGSLIVSGSYDGLCRIWDAASGQCL 202
Query: 935 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD-----IINAL 1099
KT ++ V SP+G + D LWD + G+ L T G I
Sbjct: 203 KTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANF 262
Query: 1100 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELK 1195
+ ++ + + + IW+L+ K IV +L+
Sbjct: 263 SVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ 294
Score = 89.0 bits (219), Expect = 9e-18
Identities = 67/217 (30%), Positives = 100/217 (46%), Gaps = 4/217 (1%)
Frame = +2
Query: 410 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 589
TLKGH+ +V P ++I+S S D+T+ +W E G + L HS VS V
Sbjct: 120 TLKGHSNYVFCCNFNPP-SNLIISGSFDETVKIW-----EVKTGKCLKTLSAHSDPVSAV 173
Query: 590 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDKT 766
+ G +SGS+DG R+WD +G + V +S V FS + + I++ + D T
Sbjct: 174 HFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNT 233
Query: 767 IKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTN 943
+KLW+ + G C T + ++ FS IVS D LV +WNL ++
Sbjct: 234 LKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGK-WIVSGSEDNLVYIWNLQTKEIVQK 292
Query: 944 HIGHTGYLNTVTVSPDGSLCASGG--KDGQAMLWDLN 1048
GHT + + P +L AS D LW N
Sbjct: 293 LQGHTDVVISAACHPTENLIASAALENDKTIKLWMSN 329
>ref|NP_002066.1| guanine nucleotide-binding protein, beta-3 subunit [Homo sapiens]
Length = 340
Score = 117 bits (292), Expect = 3e-26
Identities = 82/260 (31%), Positives = 127/260 (48%), Gaps = 5/260 (1%)
Frame = +2
Query: 548 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 727
+R LRGH + + ++D + +S S DG L +WD T + V++ A++
Sbjct: 48 RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 728 DNRQIVSGSRDKTIKLWNTL---GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDK 898
+ G D ++N G K + + +H+ ++SC RF N I+ S G D
Sbjct: 108 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFL--DDNNIVTSSG-DT 164
Query: 899 LVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 1078
+W++ + KT +GHTG ++ VSPD +L SG D A LWD+ EG T G
Sbjct: 165 TCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTG 224
Query: 1079 GDI-INALCFSPNRYWLCAAT-GPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLA 1252
+ INA+CF PN +C + S +++DL QE+I S ++ TS+A
Sbjct: 225 HESDINAICFFPNGEAICTGSDDASCRLFDLRA-------DQELICFSHESIICGITSVA 277
Query: 1253 WSADGQTLFAGYTDNLVRVW 1312
+S G+ LFAGY D VW
Sbjct: 278 FSLSGRLLFAGYDDFNCNVW 297
Score = 72.0 bits (175), Expect = 1e-12
Identities = 67/252 (26%), Positives = 105/252 (41%), Gaps = 6/252 (2%)
Frame = +2
Query: 425 NGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD 604
+ WV A P + + D ++ L E N + R L H+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNMCSIYNLKSREGNVKV-SRELSAHTGYLSCCRFLDD 154
Query: 605 GQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT 784
S S D T LWD+ TG FVGHT D +S+A S D +SG+ D + KLW+
Sbjct: 155 NNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDV 213
Query: 785 L-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCK--LKTNHIGH 955
G C+ T H ++ + F PN I + D ++++L + + +H
Sbjct: 214 REGTCRQTF--TGHESDINAICFFPNGE--AICTGSDDASCRLFDLRADQELICFSHESI 269
Query: 956 TGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAA 1135
+ +V S G L +G D +WD + + + L G D C + A
Sbjct: 270 ICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHD-NRVSCLGVTADGMAVA 328
Query: 1136 TG---PSIKIWD 1162
TG +KIW+
Sbjct: 329 TGSWDSFLKIWN 340
>ref|NP_758440.1| WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 112 bits (280), Expect = 8e-25
Identities = 79/302 (26%), Positives = 130/302 (43%), Gaps = 46/302 (15%)
Frame = +2
Query: 548 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 727
+R +GH ++ + +S +G+ + SWD L LW+ R+VGH V SV FS
Sbjct: 11 ERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSP 70
Query: 728 DNRQIVSGSRDKTIKLW-----------------------NTLGVCKYTVQDES------ 820
+ S SRD+T++LW + G T ++
Sbjct: 71 HGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWS 130
Query: 821 ------------HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGY 964
H+ WV C +FSP+ +IVSC DK +K+W+ N + N G+
Sbjct: 131 MYRQRFLYSLYRHTHWVRCAKFSPDGR--LIVSCSEDKTIKIWDTTNKQCVNNFSDSVGF 188
Query: 965 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGK---HLYTLDGGDIINALCFSPN-RYWLCA 1132
N V +P G+ AS G D +WD+ K H GG +N + F P+ Y + A
Sbjct: 189 ANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGG--VNCISFHPSGNYLITA 246
Query: 1133 ATGPSIKIWD-LEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRV 1309
++ ++KI D LEG++I + + ++++S G+ +G D V +
Sbjct: 247 SSDGTLKILDLLEGRLIY----------TLQGHTGPVFTVSFSKGGELFASGGADTQVLL 296
Query: 1310 WQ 1315
W+
Sbjct: 297 WR 298
Score = 109 bits (273), Expect = 5e-24
Identities = 76/226 (33%), Positives = 114/226 (50%), Gaps = 6/226 (2%)
Frame = +2
Query: 419 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-----LRGHSHFVS 583
GH VT + +P +++ SASRD+T+ +W IP + + H+ V
Sbjct: 58 GHKDVVTSVQFSPH-GNLLASASRDRTVRLW----------IPDKRGKFSEFKAHTAPVR 106
Query: 584 DVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDK 763
V S+DGQF + S D ++++W + HT V FS D R IVS S DK
Sbjct: 107 SVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDK 166
Query: 764 TIKLWNTLGVCKYTVQDESHSE-WVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 940
TIK+W+T K V + S S + + V F+P S I S G D+ VKVW++ KL
Sbjct: 167 TIKIWDTTN--KQCVNNFSDSVGFANFVDFNP--SGTCIASAGSDQTVKVWDVRVNKLLQ 222
Query: 941 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 1078
++ H+G +N ++ P G+ + DG + DL EG+ +YTL G
Sbjct: 223 HYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQG 268
Score = 95.1 bits (235), Expect = 1e-19
Identities = 61/192 (31%), Positives = 95/192 (49%)
Frame = +2
Query: 473 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 652
+ +AS DK+I +W + R Y +L H+H+V S DG+ +S S D T+++W
Sbjct: 117 LATASEDKSIKVWSMYRQRFLY-----SLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 171
Query: 653 DLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEW 832
D T F V F+ I S D+T+K+W+ + V K + HS
Sbjct: 172 DTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWD-VRVNKLLQHYQVHSGG 230
Query: 833 VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASG 1012
V+C+ F P+ + +++ D +K+ +L +L GHTG + TV+ S G L ASG
Sbjct: 231 VNCISFHPSGN--YLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASG 288
Query: 1013 GKDGQAMLWDLN 1048
G D Q +LW N
Sbjct: 289 GADTQVLLWRTN 300
Score = 51.2 bits (121), Expect = 2e-06
Identities = 38/171 (22%), Positives = 73/171 (42%), Gaps = 2/171 (1%)
Frame = +2
Query: 815 ESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDG 994
+ H ++ + SPN + + WD + +WN ++GH + +V SP G
Sbjct: 15 KGHKAAITSLDLSPNGKQ--LATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHG 72
Query: 995 SLCASGGKDGQAMLWDLNE-GKHLYTLDGGDIINALCFSPNRYWLCAAT-GPSIKIWDLE 1168
+L AS +D LW ++ GK + ++ FS + +L A+ SIK+W +
Sbjct: 73 NLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMY 132
Query: 1169 GKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 1321
+ + L + +C +S DG+ + + D +++W T
Sbjct: 133 RQRFLYSLYRHTHWV-------RCAK--FSPDGRLIVSCSEDKTIKIWDTT 174
>ref|XP_947007.1| PREDICTED: similar to CG7704-PA isoform 1 [Homo sapiens]
Length = 315
Score = 112 bits (279), Expect = 1e-24
Identities = 89/302 (29%), Positives = 135/302 (44%), Gaps = 7/302 (2%)
Frame = +2
Query: 422 HNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISS 601
H G V A +P M+L+ S D + W ET G L GH+ V S
Sbjct: 20 HGGEVNSSAFSPD-GQMLLTGSEDGCVYGW-----ETRSGQLLWRLGGHTGPVKFCRFSP 73
Query: 602 DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 781
DG S S D T+RLWD+ R GH + V +V+FS D+RQ+ SG DK + LW+
Sbjct: 74 DGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWD 133
Query: 782 TLG--VCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNH--- 946
+ + V H + + FSP + + + WD V++W+L +H
Sbjct: 134 VQSGQMLRLLV---GHRDSIQSSDFSPTVN--CLATGSWDSTVRIWDLRMVTPAVSHQAL 188
Query: 947 IGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYW 1123
GH+G ++ + S G L ASG D +W L L G + ++ FSP+ W
Sbjct: 189 EGHSGNISCLCYSASG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELW 247
Query: 1124 LCAA-TGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNL 1300
L +A +K+WD ++ LKQ V+ + + A++ DG+ L +G D
Sbjct: 248 LASAGYSRMVKVWDCNTGKCLETLKQGVLDVAH--------TCAFTPDGKILVSGAADQT 299
Query: 1301 VR 1306
R
Sbjct: 300 RR 301
Score = 84.7 bits (208), Expect = 2e-16
Identities = 68/217 (31%), Positives = 104/217 (47%), Gaps = 4/217 (1%)
Frame = +2
Query: 683 FVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNS 862
F H +V S AFS D + +++GS D + W T + + H+ V RFSP+
Sbjct: 17 FGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRS-GQLLWRLGGHTGPVKFCRFSPDG 75
Query: 863 SNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWD 1042
+ S D V++W++A K GH + TV+ SPD ASGG D + MLWD
Sbjct: 76 H--LFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWD 133
Query: 1043 LNEGKHLYTLDG-GDIINALCFSPNRYWLCAATG---PSIKIWDLEGKIIVDELKQEVIS 1210
+ G+ L L G D I + FSP C ATG +++IWDL +++ + + +
Sbjct: 134 VQSGQMLRLLVGHRDSIQSSDFSPTVN--CLATGSWDSTVRIWDL--RMVTPAVSHQALE 189
Query: 1211 TSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 1321
S + L +SA G L +G D + +W+ T
Sbjct: 190 GHS----GNISCLCYSASG-LLASGSWDKTIHIWKPT 221
Database: RefSeqHP
Posted date: Aug 2, 2006 12:57 AM
Number of letters in database: 17,774,539
Number of sequences in database: 39,411
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,415,522
Number of Sequences: 39411
Number of extensions: 1765145
Number of successful extensions: 8423
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 5018
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6991
length of database: 17,774,539
effective HSP length: 106
effective length of database: 13,596,973
effective search space used: 4935701199
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqMP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-005279
(1411 letters)
Database: RefSeqMP
45,328 sequences; 21,768,885 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_032169.1| guanine nucleotide binding protein (G protein),... 659 0.0
Alignment gi|NP_082016.1| WD repeat domain 51B [Mus musculus] 132 7e-31
Alignment gi|NP_038653.1| platelet-activating factor acetylhydrolase, iso... 131 2e-30
Alignment gi|NP_543124.1| WD repeat domain 5 [Mus musculus] 123 4e-28
Alignment gi|NP_038558.1| guanine nucleotide-binding protein, beta-3 subu... 116 7e-26
Alignment gi|XP_987745.1| PREDICTED: similar to platelet-activating facto... 115 9e-26
Alignment gi|NP_081389.1| WD repeat domain 5B [Mus musculus] 113 6e-25
Alignment gi|NP_083963.1| hypothetical protein LOC76646 [Mus musculus] 109 8e-24
Alignment gi|NP_081630.1| WD repeat domain 51A [Mus musculus] 107 2e-23
Alignment gi|NP_663406.1| Notchless gene homolog [Mus musculus] 104 2e-22
>ref|NP_032169.1| guanine nucleotide binding protein (G protein), beta polypeptide 2
like 1 [Mus musculus]
Length = 317
Score = 659 bits (1701), Expect = 0.0
Identities = 316/317 (99%), Positives = 316/317 (99%)
Frame = +2
Query: 383 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 562
MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 563 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 742
GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 743 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 922
VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 923 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC 1102
NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC 240
Query: 1103 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 1282
FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA
Sbjct: 241 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
Query: 1283 GYTDNLVRVWQVTIGPR 1333
GYTDNLVRVWQVTIG R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
>ref|NP_082016.1| WD repeat domain 51B [Mus musculus]
Length = 476
Score = 132 bits (333), Expect = 7e-31
Identities = 93/314 (29%), Positives = 146/314 (46%), Gaps = 5/314 (1%)
Frame = +2
Query: 389 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGH 568
E L + KGH +T +P I +AS D +++W L Y GH
Sbjct: 6 EDPILERSFKGHKAAITSADFSPNCKQ-IATASWDTFLMLWSLKPHARAYRYV-----GH 59
Query: 569 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 748
V+ + S G S S D T+RLW L + F HT V SV FS+D + +V+
Sbjct: 60 KDVVTSLQFSPQGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVT 119
Query: 749 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 928
S DK+IK+W+ ++ H+ WV C +FSP+ +IVSC DK +K+W+ N
Sbjct: 120 ASEDKSIKVWSMFRQ-RFLYSLYRHTHWVRCAKFSPDGR--LIVSCSEDKTIKIWDTTNK 176
Query: 929 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK---HLYTLDGGDIINAL 1099
+ N G+ N V +P+G+ AS G D +WD+ K H G +N L
Sbjct: 177 QCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQHYQVHSCG--VNCL 234
Query: 1100 CFSP-NRYWLCAATGPSIKIWDL-EGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQT 1273
F P + A++ ++K+ DL EG++I + + ++++S DG+
Sbjct: 235 SFHPLGNSLVTASSDGTVKMLDLIEGRLIY----------TLQGHTGPVFTVSFSKDGEL 284
Query: 1274 LFAGYTDNLVRVWQ 1315
L +G D V +W+
Sbjct: 285 LTSGGADAQVLIWR 298
Score = 99.0 bits (245), Expect = 1e-20
Identities = 77/253 (30%), Positives = 112/253 (44%), Gaps = 43/253 (16%)
Frame = +2
Query: 419 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 598
GH VT + +PQ +++ SASRD+T+ +W L R + + H+ V V S
Sbjct: 58 GHKDVVTSLQFSPQ-GNLLASASRDRTVRLWVLDRKGKS-----SEFKAHTAPVRSVDFS 111
Query: 599 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 778
+DGQ ++ S D ++++W + HT V FS D R IVS S DKTIK+W
Sbjct: 112 ADGQLLVTASEDKSIKVWSMFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 171
Query: 779 NTLGVCKYTVQDESHSE-WVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI-- 949
+T K V + S S + + V F+PN + I S G D VK+W++ KL ++
Sbjct: 172 DTTN--KQCVNNFSDSVGFANFVDFNPNGT--CIASAGSDHAVKIWDIRMNKLLQHYQVH 227
Query: 950 ----------------------------------------GHTGYLNTVTVSPDGSLCAS 1009
GHTG + TV+ S DG L S
Sbjct: 228 SCGVNCLSFHPLGNSLVTASSDGTVKMLDLIEGRLIYTLQGHTGPVFTVSFSKDGELLTS 287
Query: 1010 GGKDGQAMLWDLN 1048
GG D Q ++W N
Sbjct: 288 GGADAQVLIWRTN 300
Score = 53.1 bits (126), Expect = 7e-07
Identities = 40/171 (23%), Positives = 74/171 (43%), Gaps = 2/171 (1%)
Frame = +2
Query: 815 ESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDG 994
+ H ++ FSPN I + WD + +W+L ++GH + ++ SP G
Sbjct: 15 KGHKAAITSADFSPNCKQ--IATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFSPQG 72
Query: 995 SLCASGGKDGQAMLWDLN-EGKHLYTLDGGDIINALCFSPNRYWLCAAT-GPSIKIWDLE 1168
+L AS +D LW L+ +GK + ++ FS + L A+ SIK+W +
Sbjct: 73 NLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWSMF 132
Query: 1169 GKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 1321
+ + L + +C +S DG+ + + D +++W T
Sbjct: 133 RQRFLYSLYRHTHWV-------RCAK--FSPDGRLIVSCSEDKTIKIWDTT 174
>ref|NP_038653.1| platelet-activating factor acetylhydrolase, isoform 1b, beta1 subunit
[Mus musculus]
Length = 410
Score = 131 bits (330), Expect = 2e-30
Identities = 99/324 (30%), Positives = 141/324 (43%), Gaps = 23/324 (7%)
Frame = +2
Query: 413 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 592
L GH VT++ P F M+ SAS D TI +W + G +R L+GH+ V D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVQDIS 157
Query: 593 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 772
G+ S S D T++LWD R GH +V SVA + IVS SRDKTIK
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 217
Query: 773 LWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 949
+W G C T H EWV VR PN +I SC D+ V+VW +A + K
Sbjct: 218 MWEVQTGYCVKTF--TGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 273
Query: 950 GHTGYLNTVTVSPD--------------------GSLCASGGKDGQAMLWDLNEGKHLYT 1069
H + ++ +P+ G SG +D +WD++ G L T
Sbjct: 274 EHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMT 333
Query: 1070 LDGGD--IINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCT 1243
L G D + L S ++ L A ++++WD + K + L A T
Sbjct: 334 LVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTL---------NAHEHFVT 384
Query: 1244 SLAWSADGQTLFAGYTDNLVRVWQ 1315
SL + + G D V+VW+
Sbjct: 385 SLDFHKTAPYVVTGSVDQTVKVWE 408
>ref|NP_543124.1| WD repeat domain 5 [Mus musculus]
Length = 334
Score = 123 bits (309), Expect = 4e-28
Identities = 89/275 (32%), Positives = 141/275 (51%), Gaps = 6/275 (2%)
Frame = +2
Query: 512 KLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVG 691
K T + NY + + L GH+ VS V S +G++ S S D +++W G + G
Sbjct: 27 KPTPVKPNYAL-KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISG 85
Query: 692 HTKDVLSVAFSSDNRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSN 868
H + VA+SSD+ +VS S DKT+K+W+ + G C T++ HS +V C F+P S+
Sbjct: 86 HKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK--GHSNYVFCCNFNPQSN- 142
Query: 869 PIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 1048
+IVS +D+ V++W++ K H+ ++ V + DGSL S DG +WD
Sbjct: 143 -LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA 201
Query: 1049 EGKHLYTL--DGGDIINALCFSPN-RYWLCAATGPSIKIWDL-EGKIIVDELKQEVISTS 1216
G+ L TL D ++ + FSPN +Y L A ++K+WD +GK + T
Sbjct: 202 SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTY-------TG 254
Query: 1217 SKAEPPQCTSLAWSADG-QTLFAGYTDNLVRVWQV 1318
K E C +S G + + +G DNLV +W +
Sbjct: 255 HKNEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNL 288
Score = 112 bits (281), Expect = 7e-25
Identities = 86/282 (30%), Positives = 141/282 (50%), Gaps = 10/282 (3%)
Frame = +2
Query: 401 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 580
L+ TL GH V+ + +P + + S+S DK I +W G ++ + GH +
Sbjct: 37 LKFTLAGHTKAVSSVKFSPN-GEWLASSSADKLIKIWGAYD-----GKFEKTISGHKLGI 90
Query: 581 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRD 760
SDV SSD +S S D TL++WD+++G + GH+ V F+ + IVSGS D
Sbjct: 91 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 150
Query: 761 KTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCK-L 934
+++++W+ G C T+ +HS+ VS V F N +IVS +D L ++W+ A+ + L
Sbjct: 151 ESVRIWDVKTGKCLKTL--PAHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDTASGQCL 206
Query: 935 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD-----IINAL 1099
KT ++ V SP+G + D LWD ++GK L T G I
Sbjct: 207 KTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANF 266
Query: 1100 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELK---QEVISTS 1216
+ ++ + + + IW+L+ K IV +L+ VIST+
Sbjct: 267 SVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTA 308
Score = 86.7 bits (213), Expect = 6e-17
Identities = 63/214 (29%), Positives = 100/214 (46%), Gaps = 4/214 (1%)
Frame = +2
Query: 410 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 589
TLKGH+ +V PQ ++I+S S D+++ +W + G + L HS VS V
Sbjct: 124 TLKGHSNYVFCCNFNPQ-SNLIVSGSFDESVRIW-----DVKTGKCLKTLPAHSDPVSAV 177
Query: 590 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDKT 766
+ DG +S S+DG R+WD +G + + +S V FS + + I++ + D T
Sbjct: 178 HFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNT 237
Query: 767 IKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTN 943
+KLW+ + G C T + ++ FS IVS D LV +WNL ++
Sbjct: 238 LKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK-WIVSGSEDNLVYIWNLQTKEIVQK 296
Query: 944 HIGHTGYLNTVTVSPDGSLCASGG--KDGQAMLW 1039
GHT + + P ++ AS D LW
Sbjct: 297 LQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 68.6 bits (166), Expect = 2e-11
Identities = 48/172 (27%), Positives = 80/172 (46%), Gaps = 3/172 (1%)
Frame = +2
Query: 821 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSL 1000
H++ VS V+FSPN + S DKL+K+W + K + GH ++ V S D +L
Sbjct: 44 HTKAVSSVKFSPNGE--WLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNL 101
Query: 1001 CASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC-FSPNRYWLCAAT-GPSIKIWDLE-G 1171
S D +WD++ GK L TL G C F+P + + + S++IWD++ G
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTG 161
Query: 1172 KIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 1327
K + + A +++ ++ DG + + D L R+W G
Sbjct: 162 KCL----------KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG 203
>ref|NP_038558.1| guanine nucleotide-binding protein, beta-3 subunit [Mus musculus]
Length = 340
Score = 116 bits (290), Expect = 7e-26
Identities = 81/260 (31%), Positives = 126/260 (48%), Gaps = 5/260 (1%)
Frame = +2
Query: 548 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 727
+R LRGH + + ++D + +S S DG L +WD T + V++ A++
Sbjct: 48 RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 728 DNRQIVSGSRDKTIKLWNTL---GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDK 898
+ G D ++N G K + + +H+ ++SC RF N I+ S G D
Sbjct: 108 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFL--DDNNIVTSSG-DT 164
Query: 899 LVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 1078
+W++ + KT +GHTG ++ VSPD L SG D A LWD+ EG T G
Sbjct: 165 TCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTG 224
Query: 1079 GDI-INALCFSPNRYWLCAAT-GPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLA 1252
+ INA+CF PN +C + S +++DL QE+ + S ++ TS+A
Sbjct: 225 HESDINAICFFPNGEAICTGSDDASCRLFDLRA-------DQELTAYSQESIICGITSVA 277
Query: 1253 WSADGQTLFAGYTDNLVRVW 1312
+S G+ LFAGY D VW
Sbjct: 278 FSLSGRLLFAGYDDFNCNVW 297
Score = 71.2 bits (173), Expect = 2e-12
Identities = 67/252 (26%), Positives = 106/252 (42%), Gaps = 6/252 (2%)
Frame = +2
Query: 425 NGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD 604
+ WV A P + + D ++ L E N + R L H+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNMCSIYNLKSREGNVKV-SRELSAHTGYLSCCRFLDD 154
Query: 605 GQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT 784
S S D T LWD+ TG FVGHT D +S+A S D + +SG+ D + KLW+
Sbjct: 155 NNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDV 213
Query: 785 L-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTG 961
G C+ T H ++ + F PN I + D ++++L + T + +
Sbjct: 214 REGTCRQTF--TGHESDINAICFFPNGE--AICTGSDDASCRLFDLRADQELTAYSQESI 269
Query: 962 Y--LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAA 1135
+ +V S G L +G D +WD + + + L G D C + A
Sbjct: 270 ICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHD-NRVSCLGVTADGMAVA 328
Query: 1136 TG---PSIKIWD 1162
TG +KIW+
Sbjct: 329 TGSWDSFLKIWN 340
>ref|XP_987745.1| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
subunit [Mus musculus]
Length = 312
Score = 115 bits (289), Expect = 9e-26
Identities = 83/279 (29%), Positives = 120/279 (43%), Gaps = 23/279 (8%)
Frame = +2
Query: 548 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 727
+R L+GH+ V D+ G+ S S D T++LWD R GH +V SVA
Sbjct: 45 ERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMP 104
Query: 728 DNRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 904
+ IVS SRDKTIK+W G C T H EWV VR PN +I SC D+ V
Sbjct: 105 NGDHIVSASRDKTIKMWEVQTGYCVKTF--TGHREWVRMVR--PNQDGTLIASCSNDQTV 160
Query: 905 KVWNLANCKLKTNHIGHTGYLNTVTVSPD--------------------GSLCASGGKDG 1024
+VW +A + K H + ++ +P+ G SG +D
Sbjct: 161 RVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDK 220
Query: 1025 QAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQ 1198
+WD++ G L TL G D + L S ++ L A ++++WD + K + L
Sbjct: 221 TIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTL-- 278
Query: 1199 EVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQ 1315
A TSL + + G D V+VW+
Sbjct: 279 -------NAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 310
Score = 89.7 bits (221), Expect = 7e-18
Identities = 69/232 (29%), Positives = 108/232 (46%), Gaps = 21/232 (9%)
Frame = +2
Query: 410 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 589
T+ GH+ V+ +A P D I+SASRDKTI MW++ +T Y + + GH +V V
Sbjct: 89 TMHGHDHNVSSVAIMPN-GDHIVSASRDKTIKMWEV---QTGYCV--KTFTGHREWVRMV 142
Query: 590 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDV-------------LSVAFSSD 730
+ DG S S D T+R+W + T H V +S A S+
Sbjct: 143 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 202
Query: 731 NRQ-------IVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSC 886
++ ++SGSRDKTIK+W+ + G+C T+ H WV V F +S I+SC
Sbjct: 203 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL--VGHDNWVRGVLF--HSGGKFILSC 258
Query: 887 GWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWD 1042
DK ++VW+ N + H ++ ++ +G D +W+
Sbjct: 259 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 310
>ref|NP_081389.1| WD repeat domain 5B [Mus musculus]
Length = 328
Score = 113 bits (282), Expect = 6e-25
Identities = 92/311 (29%), Positives = 150/311 (48%), Gaps = 7/311 (2%)
Frame = +2
Query: 401 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 580
LR TL GH+ ++ + +P + + S++ D II+W G ++ L GHS +
Sbjct: 31 LRLTLAGHSAAISSVKFSPN-GEWLASSAADALIIIWGAYD-----GNCKKTLYGHSLEI 84
Query: 581 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRD 760
SDV SSD +S S D TL++WD+ +G + GH+ V F+ + IVSGS D
Sbjct: 85 SDVAWSSDSSRLVSASDDKTLKVWDMRSGKCLKTLKGHSDFVFCCDFNPPSNLIVSGSFD 144
Query: 761 KTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCK-L 934
+++K+W G C T+ +HS+ +S V F+ N S +IVS +D L ++W+ A+ + L
Sbjct: 145 ESVKIWEVKTGKCLKTL--SAHSDPISAVNFNCNGS--LIVSGSYDGLCRIWDAASGQCL 200
Query: 935 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS-- 1108
+T ++ V SP+G + D LWD + G+ L T G F+
Sbjct: 201 RTLADEGNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCLFASF 260
Query: 1109 --PNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 1279
R W+ + + + + IW+L+ K IV L+ S A P +A +
Sbjct: 261 SVTGRKWVVSGSEDNMVYIWNLQTKEIVQRLQGHTDVVISAACHPTKNIIASA------- 313
Query: 1280 AGYTDNLVRVW 1312
A D ++VW
Sbjct: 314 ALENDKTIKVW 324
>ref|NP_083963.1| hypothetical protein LOC76646 [Mus musculus]
Length = 303
Score = 109 bits (272), Expect = 8e-24
Identities = 75/247 (30%), Positives = 115/247 (46%), Gaps = 4/247 (1%)
Frame = +2
Query: 386 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 565
T+ L L GH G V +P +I S+S D +I +W + R + + L+G
Sbjct: 55 TKSGRLLWRLAGHRGPVKSCCFSPD-GRLIASSSSDHSIRLWDVARSKCLH-----VLKG 108
Query: 566 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 745
H V V S D + SG WD +W++ +G VGH + S FS + +
Sbjct: 109 HQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLA 168
Query: 746 SGSRDKTIKLWN---TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 916
+GS D T+ +W+ + V Y E H+ +SC+ +S + ++ S WDK + VW
Sbjct: 169 TGSWDSTVHIWDLRASTPVVSYH-NLEGHTGNISCLCYSASG---LLASGSWDKTICVWK 224
Query: 917 LANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIIN 1093
L GHT ++N++ SPD AS G +WD GK L TL G D+ +
Sbjct: 225 PTTNNLPLQLKGHTIWVNSLAFSPDELKLASAGYSRTVKVWDCLTGKCLETLKGMLDVAH 284
Query: 1094 ALCFSPN 1114
A F+P+
Sbjct: 285 ACIFTPD 291
Score = 95.1 bits (235), Expect = 2e-19
Identities = 79/259 (30%), Positives = 120/259 (46%), Gaps = 6/259 (2%)
Frame = +2
Query: 422 HNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISS 601
H+G V A +P +L+AS D + +W T G L GH V S
Sbjct: 25 HHGEVNCSAFSPD-GRTLLTASDDGCVYVWG-----TKSGRLLWRLAGHRGPVKSCCFSP 78
Query: 602 DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 781
DG+ S S D ++RLWD+ GH + V +V+FS D++Q+ SG DK +W
Sbjct: 79 DGRLIASSSSDHSIRLWDVARSKCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWE 138
Query: 782 TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNH--IG 952
+ + H + + FSP S + + + WD V +W+L A+ + + H G
Sbjct: 139 VQSGRRVHLL-VGHCDSIQSSDFSPTSDS--LATGSWDSTVHIWDLRASTPVVSYHNLEG 195
Query: 953 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLC 1129
HTG ++ + S G L ASG D +W L G I +N+L FSP+ L
Sbjct: 196 HTGNISCLCYSASG-LLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFSPDELKLA 254
Query: 1130 AA-TGPSIKIWD-LEGKII 1180
+A ++K+WD L GK +
Sbjct: 255 SAGYSRTVKVWDCLTGKCL 273
Score = 92.8 bits (229), Expect = 8e-19
Identities = 75/259 (28%), Positives = 111/259 (42%), Gaps = 5/259 (1%)
Frame = +2
Query: 566 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 745
H V+ S DG+ L+ S DG + +W +G R GH V S FS D R I
Sbjct: 25 HHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIA 84
Query: 746 SGSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 922
S S D +I+LW+ C + ++ H V V FSP+S + S GWDK VW +
Sbjct: 85 SSSSDHSIRLWDVARSKCLHVLK--GHQRSVETVSFSPDSKQ--LASGGWDKRAIVWEVQ 140
Query: 923 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHL---YTLDGGD-II 1090
+ + +GH + + SP A+G D +WDL + + L+G I
Sbjct: 141 SGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWDLRASTPVVSYHNLEGHTGNI 200
Query: 1091 NALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQ 1270
+ LC+S + + +I +W + +LK I +S A P LA
Sbjct: 201 SCLCYSASGLLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFSPDELKLA------ 254
Query: 1271 TLFAGYTDNLVRVWQVTIG 1327
AGY+ V+VW G
Sbjct: 255 --SAGYS-RTVKVWDCLTG 270
Score = 82.8 bits (203), Expect = 8e-16
Identities = 59/203 (29%), Positives = 87/203 (42%), Gaps = 3/203 (1%)
Frame = +2
Query: 413 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 592
LKGH V ++ +P + S DK I+W E G L GH +
Sbjct: 106 LKGHQRSVETVSFSPD-SKQLASGGWDKRAIVW-----EVQSGRRVHLLVGHCDSIQSSD 159
Query: 593 ISSDGQFALSGSWDGTLRLWDLTTGTTT---RRFVGHTKDVLSVAFSSDNRQIVSGSRDK 763
S +GSWD T+ +WDL T GHT ++ + +S+ + SGS DK
Sbjct: 160 FSPTSDSLATGSWDSTVHIWDLRASTPVVSYHNLEGHTGNISCLCYSASGL-LASGSWDK 218
Query: 764 TIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTN 943
TI +W +Q + H+ WV+ + FSP+ + S G+ + VKVW+ K
Sbjct: 219 TICVWKPT-TNNLPLQLKGHTIWVNSLAFSPDELK--LASAGYSRTVKVWDCLTGKCLET 275
Query: 944 HIGHTGYLNTVTVSPDGSLCASG 1012
G + +PDG L SG
Sbjct: 276 LKGMLDVAHACIFTPDGKLLVSG 298
Score = 49.7 bits (117), Expect = 8e-06
Identities = 32/114 (28%), Positives = 57/114 (50%)
Frame = +2
Query: 413 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 592
L+GH G ++ + + ++ S S DKTI +WK T + +P + L+GH+ +V+ +
Sbjct: 193 LEGHTGNISCLCYSAS--GLLASGSWDKTICVWKPTTNN----LPLQ-LKGHTIWVNSLA 245
Query: 593 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGS 754
S D S + T+++WD TG G + F+ D + +VSG+
Sbjct: 246 FSPDELKLASAGYSRTVKVWDCLTGKCLETLKGMLDVAHACIFTPDGKLLVSGA 299
>ref|NP_081630.1| WD repeat domain 51A [Mus musculus]
Length = 405
Score = 107 bits (268), Expect = 2e-23
Identities = 83/301 (27%), Positives = 132/301 (43%), Gaps = 45/301 (14%)
Frame = +2
Query: 548 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 727
+R +GH V+ V S + + SGS D TL +W + + + RF GH V V FS
Sbjct: 12 ERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSP 71
Query: 728 DNRQIVSGSRDKTIKLW-------NTL----------------GVCKYTVQDE------- 817
+ SGSRDKT+++W +T+ G T D+
Sbjct: 72 SGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWS 131
Query: 818 -----------SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGY 964
H WV C +FSP+ +IVS DK VK+W+ + + ++ H G+
Sbjct: 132 THRQRFLFSLTQHINWVRCAKFSPDGR--LIVSASDDKTVKLWDKTSRECIHSYCEHGGF 189
Query: 965 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHL--YTLDGGDIINALCFSPN-RYWLCAA 1135
+ V P G+ A+ G D +WD + L Y L +NAL F P+ Y + A+
Sbjct: 190 VTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSA-AVNALSFHPSGNYLITAS 248
Query: 1136 TGPSIKIWDL-EGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVW 1312
+ ++KI DL EG+++ + T++A+S G+ +G +D V VW
Sbjct: 249 SDSTLKILDLMEGRLLY----------TLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
Query: 1313 Q 1315
+
Sbjct: 299 K 299
Score = 102 bits (254), Expect = 1e-21
Identities = 79/301 (26%), Positives = 118/301 (39%), Gaps = 44/301 (14%)
Frame = +2
Query: 389 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGH 568
E +L KGH VT + + + S S D T+++W + Y GH
Sbjct: 7 EDPSLERHFKGHRDAVTCVDFSLNTKHLA-SGSMDSTLMIWHMKSQSRAY-----RFTGH 60
Query: 569 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 748
V+ V S G SGS D T+R+W + F HT V SV F SD + +V+
Sbjct: 61 KDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVT 120
Query: 749 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 928
S DKT+K+W+T ++ H WV C +FSP+ +IVS DK VK+W+ +
Sbjct: 121 ASDDKTVKVWSTHRQ-RFLFSLTQHINWVRCAKFSPDGR--LIVSASDDKTVKLWDKTSR 177
Query: 929 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWD---------------------- 1042
+ ++ H G++ V P G+ A+ G D +WD
Sbjct: 178 ECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSF 237
Query: 1043 --------------------LNEGKHLYTLDG--GDIINALCFSPNRYWLCAATGPSIKI 1156
L EG+ LYTL G G Y+ + + +
Sbjct: 238 HPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMV 297
Query: 1157 W 1159
W
Sbjct: 298 W 298
Score = 83.2 bits (204), Expect = 6e-16
Identities = 55/192 (28%), Positives = 88/192 (45%)
Frame = +2
Query: 473 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 652
+++AS DKT+ +W R + + Q H ++V S DG+ +S S D T++LW
Sbjct: 118 LVTASDDKTVKVWSTHRQRFLFSLTQ-----HINWVRCAKFSPDGRLIVSASDDKTVKLW 172
Query: 653 DLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEW 832
D T+ + H V V F I + D T+K+W+ + + HS
Sbjct: 173 DKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDAR-THRLLQHYQLHSAA 231
Query: 833 VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASG 1012
V+ + F P+ + +++ D +K+ +L +L GH G TV S G ASG
Sbjct: 232 VNALSFHPSGN--YLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASG 289
Query: 1013 GKDGQAMLWDLN 1048
G D Q M+W N
Sbjct: 290 GSDEQVMVWKSN 301
Score = 51.2 bits (121), Expect = 3e-06
Identities = 39/171 (22%), Positives = 74/171 (43%), Gaps = 2/171 (1%)
Frame = +2
Query: 815 ESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDG 994
+ H + V+CV FS N+ + + S D + +W++ + GH + V SP G
Sbjct: 16 KGHRDAVTCVDFSLNTKH--LASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSG 73
Query: 995 SLCASGGKDGQAMLWDLN-EGKHLYTLDGGDIINALCF-SPNRYWLCAATGPSIKIWDLE 1168
L ASG +D +W N +G+ + ++ F S + + A+ ++K+W
Sbjct: 74 HLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTH 133
Query: 1169 GKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 1321
+ + L Q + +C +S DG+ + + D V++W T
Sbjct: 134 RQRFLFSLTQHINWV-------RCAK--FSPDGRLIVSASDDKTVKLWDKT 175
>ref|NP_663406.1| Notchless gene homolog [Mus musculus]
Length = 485
Score = 104 bits (260), Expect = 2e-22
Identities = 87/352 (24%), Positives = 152/352 (43%), Gaps = 50/352 (14%)
Frame = +2
Query: 410 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQ-RALRGHSHFVSD 586
T KGH WV I+ +P + S ++ I++W + + G+ R L GHS +++
Sbjct: 151 TCKGHRHWVLSISWSPD-GKKLASGCKNGQILLW-----DPSTGLQVGRTLTGHSKWITG 204
Query: 587 VV-----ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSG 751
+ ++ + ++ S S DG++R+WD T G R GHT+ V + + D + S
Sbjct: 205 LSWEPLHMNPECRYVASSSKDGSVRVWDTTAGRCERILTGHTQSVTCLRWGGDGL-LYSA 263
Query: 752 SRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPN----------------------- 859
S+D+TIK+W GV T+Q H WV+ + S +
Sbjct: 264 SQDRTIKVWRAHDGVLCRTLQ--GHGHWVNTMALSTDYALRTGAFEPAEATVNAQDLQGS 321
Query: 860 ---------SSNPIIVSCGWDKLVK--------VWNLANCKLKTNHI-GHTGYLNTVTVS 985
S ++ G ++LV +W+ A K + GH +N V S
Sbjct: 322 LKELKERASSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFS 381
Query: 986 PDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFSPNRYWLCAATGPSIKIW 1159
PD + AS D LWD GK+L +L G + + +R + ++ ++K+W
Sbjct: 382 PDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVW 441
Query: 1160 DLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQ 1315
D+ K + ++T + ++ WS DGQ + +G D +R+W+
Sbjct: 442 DV---------KAQKLATDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 484
Score = 102 bits (254), Expect = 1e-21
Identities = 94/356 (26%), Positives = 156/356 (43%), Gaps = 53/356 (14%)
Frame = +2
Query: 410 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 589
+L+GH+ V +A +P + S S D T+ W L+ + P +GH H+V +
Sbjct: 109 SLEGHSEAVISVAFSPT-GKYLASGSGDTTVRFWDLSTET-----PHFTCKGHRHWVLSI 162
Query: 590 VISSDGQFALSGSWDGTLRLWDLTTGTTT-RRFVGHTKDVLSVAF-----SSDNRQIVSG 751
S DG+ SG +G + LWD +TG R GH+K + +++ + + R + S
Sbjct: 163 SWSPDGKKLASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASS 222
Query: 752 SRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 928
S+D ++++W+ T G C+ + H++ V+C+R+ + ++ S D+ +KVW +
Sbjct: 223 SKDGSVRVWDTTAGRCERIL--TGHTQSVTCLRW---GGDGLLYSASQDRTIKVWRAHDG 277
Query: 929 KLKTNHIGHTGYLNTVTVSPD---------------------GSL--------------- 1000
L GH ++NT+ +S D GSL
Sbjct: 278 VLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEATVNAQDLQGSLKELKERASSRYNLVR 337
Query: 1001 ------CASGGKDGQAMLWDLNEGKH-LYTLDGGD-IINALCFSP-NRYWLCAATGPSIK 1153
SG D LW E K L + G +IN + FSP +R A+ SIK
Sbjct: 338 GQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVASASFDKSIK 397
Query: 1154 IWD-LEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 1318
+WD GK + S + +AWSAD + L +G +D+ ++VW V
Sbjct: 398 LWDGRTGKYL----------ASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDV 443
Score = 64.7 bits (156), Expect = 2e-10
Identities = 58/190 (30%), Positives = 86/190 (45%), Gaps = 11/190 (5%)
Frame = +2
Query: 791 VCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI---GHTG 961
V + T E HSE V V FSP + + S D V+ W+L+ +T H GH
Sbjct: 103 VTRCTSSLEGHSEAVISVAFSP--TGKYLASGSGDTTVRFWDLST---ETPHFTCKGHRH 157
Query: 962 YLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHL-YTLDG-GDIINALCFSP------NR 1117
++ +++ SPDG ASG K+GQ +LWD + G + TL G I L + P R
Sbjct: 158 WVLSISWSPDGKKLASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECR 217
Query: 1118 YWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDN 1297
Y ++ S+++WD + E I T T L W DG L++ D
Sbjct: 218 YVASSSKDGSVRVWDTTAG------RCERILT---GHTQSVTCLRWGGDG-LLYSASQDR 267
Query: 1298 LVRVWQVTIG 1327
++VW+ G
Sbjct: 268 TIKVWRAHDG 277
Database: RefSeqMP
Posted date: Aug 2, 2006 12:58 AM
Number of letters in database: 21,768,885
Number of sequences in database: 45,328
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,671,109
Number of Sequences: 45328
Number of extensions: 2030276
Number of successful extensions: 9735
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 5892
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8290
length of database: 21,768,885
effective HSP length: 107
effective length of database: 16,918,789
effective search space used: 6124601618
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)