BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-005822
(977 letters)
Database: RefSeqSP
1040 sequences; 434,620 total letters
Searching...done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_999110.1| plasminogen activator [Sus scrofa] 542 e-156
Alignment gi|NP_999407.1| factor XII [Sus scrofa] 127 5e-31
Alignment gi|NP_999219.1| T-plasminogen activator [Sus scrofa] 126 7e-31
Alignment gi|NP_999274.1| pancreatic elastase II [Sus scrofa] 49 2e-07
Alignment gi|NP_001001911.1| kallikrein 1, renal/pancreas/salivary [Sus s... 48 3e-07
Alignment gi|NP_998967.1| enamel matrix serine proteinase 1 [Sus scrofa] 46 2e-06
Alignment gi|NP_999198.1| preproacrosin [Sus scrofa] 45 3e-06
Alignment gi|NP_999239.1| kallikrein [Sus scrofa] 44 8e-06
>ref|NP_999110.1| plasminogen activator [Sus scrofa]
Length = 442
Score = 542 bits (1397), Expect = e-156
Identities = 253/267 (94%), Positives = 254/267 (95%), Gaps = 1/267 (0%)
Frame = +2
Query: 179 SDSKGSHELHQESGASNCGCLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEG 358
SDSKGSHELHQESGASNCGCLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEG
Sbjct: 16 SDSKGSHELHQESGASNCGCLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEG 75
Query: 359 NGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWC 538
NGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWC
Sbjct: 76 NGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWC 135
Query: 539 YVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQKALRPRFKIVGGKS 718
YVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQKALRPRFKIVGGKS
Sbjct: 136 YVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQKALRPRFKIVGGKS 195
Query: 719 TTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLGRQPF 898
TTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLGRQ
Sbjct: 196 TTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLGRQTL 255
Query: 899 TPALMGR*N*G-GKLILHEDYSADSLA 976
+ G KLILHEDYSADSLA
Sbjct: 256 HSSTHGEMKFEVEKLILHEDYSADSLA 282
>ref|NP_999407.1| factor XII [Sus scrofa]
Length = 616
Score = 127 bits (318), Expect = 5e-31
Identities = 85/259 (32%), Positives = 107/259 (41%), Gaps = 41/259 (15%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
CLNGG C+ + + C CP + G C++D + C+ G SYRG A T G PC
Sbjct: 183 CLNGGSCLQTE---GHRLCRCPTGYAGRLCDVDLKERCYSDRGLSYRGMAQTTLSGAPCQ 239
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
PW S N AL GLG H +CRNPDN RPWC+V G + Q C + C
Sbjct: 240 PWASEATYWN---MTAEQALNWGLGDHAFCRNPDNDTRPWCFVWRGDQLSWQYCRLARCQ 296
Query: 596 G--GE--------------------SHRPAYDGKNPFST---------------PEKVEF 664
GE S P + P P
Sbjct: 297 APIGEAPPILTPTQSPSEHQDSPLLSREPQPTTQTPSQNLTSAWCAPPEQRGPLPSAGLV 356
Query: 665 QCGQKALRPRF----KIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSA 832
CGQ+ LR R +IVGG P+ AA+Y C GSLI+PCWV++A
Sbjct: 357 GCGQR-LRKRLSSLNRIVGGLVALPGAHPYIAALYWGQN------FCAGSLIAPCWVLTA 409
Query: 833 THCFINYQHKEDYIVYLGR 889
HC N E+ V LG+
Sbjct: 410 AHCLQNRPAPEELTVVLGQ 428
>ref|NP_999219.1| T-plasminogen activator [Sus scrofa]
Length = 562
Score = 126 bits (317), Expect = 7e-31
Identities = 69/185 (37%), Positives = 89/185 (48%), Gaps = 2/185 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
+ C+ G G YRG + G CLPWNS ++ Y A +A LGLGKHNYCRNPD
Sbjct: 213 EECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDG 272
Query: 521 QRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQKALR-PRF 697
+PWC+V K + C +P C CG + + P+F
Sbjct: 273 DTQPWCHVLKDHKLTWEYCDLPQC-----------------------VTCGLRQYKEPQF 309
Query: 698 KIVGGKSTTIENQPWFAAIY-RRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYI 874
+I GG I + PW AAI+ + R ++CGG LIS CWV+SA HCF
Sbjct: 310 RIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQERFPPHHVR 369
Query: 875 VYLGR 889
V LGR
Sbjct: 370 VVLGR 374
Score = 125 bits (314), Expect = 2e-30
Identities = 57/132 (43%), Positives = 73/132 (55%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
C NGG C+ YFS+ C CP F G CEID TC+E G +YRG +T G C+
Sbjct: 91 CFNGGTCLQAIYFSDFV-CQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESGAECV 149
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
WN++ + Y+ RPDA++LGLG HNYCRNPD +PWCY+ K C P C+
Sbjct: 150 NWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYSPDFCSTPACT 209
Query: 596 GGESHRPAYDGK 631
+ Y GK
Sbjct: 210 --KEKEECYTGK 219
>ref|NP_999274.1| pancreatic elastase II [Sus scrofa]
Length = 269
Score = 48.5 bits (114), Expect = 2e-07
Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 668 CGQKALRPRF-KIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCF 844
CG A P+ ++VGG+ + PW ++ + G + CGG+L+ WV++A HC
Sbjct: 17 CGLPANLPQLPRVVGGEDARPNSWPWQVSL-QYDSSGQWRHTCGGTLVDQSWVLTAAHCI 75
Query: 845 INYQHKEDYIVYLGRQPFTPALMGR*N*G-GKLILHEDYSADSLA 976
Y V LGR + G KL++H+D++++ L+
Sbjct: 76 ---SSSRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLS 117
>ref|NP_001001911.1| kallikrein 1, renal/pancreas/salivary [Sus scrofa]
Length = 263
Score = 48.1 bits (113), Expect = 3e-07
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +2
Query: 698 KIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIV 877
+I+GG+ ++ PW AIY ++ CGG L+ P WV++A HC ++Y V
Sbjct: 24 RIIGGRECEKDSHPWQVAIYHYS-----SFQCGGVLVDPKWVLTAAHC-----KNDNYQV 73
Query: 878 YLGR 889
+LGR
Sbjct: 74 WLGR 77
>ref|NP_998967.1| enamel matrix serine proteinase 1 [Sus scrofa]
Length = 254
Score = 45.8 bits (107), Expect = 2e-06
Identities = 24/68 (35%), Positives = 33/68 (48%)
Frame = +2
Query: 701 IVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVY 880
I+ G+ +QPW AA++ + CGG L+ P WV+SA HCF N Y +
Sbjct: 31 IINGEDCNPHSQPWQAALFLED-----DFFCGGVLVHPQWVLSAAHCFQN-----SYTIG 80
Query: 881 LGRQPFTP 904
LG P
Sbjct: 81 LGLHNLEP 88
>ref|NP_999198.1| preproacrosin [Sus scrofa]
Length = 400
Score = 44.7 bits (104), Expect = 3e-06
Identities = 32/110 (29%), Positives = 51/110 (46%), Gaps = 13/110 (11%)
Frame = +2
Query: 668 CG---QKALRPRFKIVGGKSTTIENQPWFAA--IYRRHRGGSVTYVCGGSLISPCWVVSA 832
CG ++ L ++VGG S PW + I+ H + CGG L++ WV++A
Sbjct: 25 CGLRFRQKLESGMRVVGGMSAEPGAWPWMVSLQIFMYHNNRRY-HTCGGILLNSHWVLTA 83
Query: 833 THCFINYQHKEDY--------IVYLGRQPFTPALMGR*N*GGKLILHEDY 958
HCF N + D+ +V+ +P P L R ++I+HE Y
Sbjct: 84 AHCFKNKKKVTDWRLIFGANEVVWGSNKPVKPPLQER--FVEEIIIHEKY 131
>ref|NP_999239.1| kallikrein [Sus scrofa]
Length = 643
Score = 43.5 bits (101), Expect = 8e-06
Identities = 21/69 (30%), Positives = 37/69 (53%)
Frame = +2
Query: 680 ALRPRFKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQH 859
A + +IVGG + + PW ++ + R + ++CGGS+I WV++A HCF
Sbjct: 392 ATKANTRIVGGTDSFLGEWPWQVSLQAKLRAQN--HLCGGSIIGHQWVLTAAHCFDGLSL 449
Query: 860 KEDYIVYLG 886
+ + +Y G
Sbjct: 450 PDIWRIYGG 458
Database: RefSeqSP
Posted date: Aug 1, 2006 7:14 PM
Number of letters in database: 434,620
Number of sequences in database: 1040
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,051,200
Number of Sequences: 1040
Number of extensions: 30017
Number of successful extensions: 125
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 113
length of database: 434,620
effective HSP length: 77
effective length of database: 354,540
effective search space used: 87925920
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqBP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-005822
(977 letters)
Database: RefSeqBP
33,508 sequences; 16,112,626 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_776572.1| plasminogen activator, urokinase [Bos taurus] 423 e-118
Alignment gi|NP_001014868.1| hyaluronan binding protein 2 [Bos taurus] 136 2e-32
Alignment gi|NP_776571.2| plasminogen activator, tissue [Bos taurus] 129 3e-30
Alignment gi|XP_888406.1| PREDICTED: similar to Coagulation factor XII pr... 122 3e-28
Alignment gi|XP_875628.1| PREDICTED: similar to Coagulation factor XII pr... 118 6e-27
Alignment gi|XP_588610.2| PREDICTED: similar to Coagulation factor XII pr... 118 6e-27
Alignment gi|XP_888407.1| PREDICTED: similar to Coagulation factor XII pr... 116 3e-26
Alignment gi|XP_580402.2| PREDICTED: similar to HGF activator preproprote... 100 2e-21
Alignment gi|NP_776376.1| plasminogen [Bos taurus] 92 6e-19
Alignment gi|NP_001026921.1| hepatocyte growth factor [Bos taurus] 80 3e-15
>ref|NP_776572.1| plasminogen activator, urokinase [Bos taurus]
Length = 433
Score = 423 bits (1087), Expect = e-118
Identities = 199/267 (74%), Positives = 220/267 (82%), Gaps = 1/267 (0%)
Frame = +2
Query: 179 SDSKGSHELHQESGASNCGCLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEG 358
SDS GS+E+H+ESG SNCGCLNGGKCV+YKYFSNIQRCSCPKKFQGEHCEIDTS+TC++G
Sbjct: 16 SDSDGSNEVHKESGESNCGCLNGGKCVTYKYFSNIQRCSCPKKFQGEHCEIDTSKTCYQG 75
Query: 359 NGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWC 538
NGHSYRGKAN + GRPCL W+S TVLL YHAHR DA+QLGLGKHNYCRNPDNQRRPWC
Sbjct: 76 NGHSYRGKANRDLSGRPCLAWDSPTVLLKMYHAHRSDAIQLGLGKHNYCRNPDNQRRPWC 135
Query: 539 YVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQKALRPRFKIVGGKS 718
YVQ+GLKQ VQ CMV +CS GK+P S EK EFQCGQKALRPRFKIVGG+
Sbjct: 136 YVQIGLKQFVQFCMVQDCS---------VGKSPSSPREKEEFQCGQKALRPRFKIVGGQV 186
Query: 719 TTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLGRQPF 898
T ENQPWFAAIYRRHRGGS+TY+CGGSLISPCWVVSATHCFI++ KE+YIVYLG+
Sbjct: 187 TNAENQPWFAAIYRRHRGGSITYLCGGSLISPCWVVSATHCFIDHPKKENYIVYLGQSRL 246
Query: 899 TPALMGR*N*G-GKLILHEDYSADSLA 976
G KLILHEDYSA+SLA
Sbjct: 247 NSDTRGEMQFEVEKLILHEDYSAESLA 273
>ref|NP_001014868.1| hyaluronan binding protein 2 [Bos taurus]
Length = 558
Score = 136 bits (343), Expect = 2e-32
Identities = 82/230 (35%), Positives = 121/230 (52%), Gaps = 8/230 (3%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
C NGG C + S C+CP +F+G+ CEI C+ +G+SYRG+ + CL
Sbjct: 157 CQNGGTCSRQRRRSKFT-CACPDQFKGKLCEIGPDD-CYVDDGYSYRGRVSKTIHQHTCL 214
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQV-GLKQLVQECMVPNC 592
WNS +L Y+ DA G+G+HN+CRNPD ++PWC+++V +K + C VP C
Sbjct: 215 YWNSHLLLQEKYNMFMEDAEAHGIGEHNFCRNPDGDKKPWCFIKVNNVKVKWEYCDVPAC 274
Query: 593 SGGESHRPAYDGKNPFSTPEKVEF-QCGQKALRPR--FKIVGGKSTTIENQPWFAAIYRR 763
S + P +G+ + EF CG+ + + +I GG +T PW A++
Sbjct: 275 SALDVANP--EGRPTEPLTKFPEFGSCGRTEIAEKKVKRIFGGFKSTAGKHPWQASLQTS 332
Query: 764 HRGGSVT---YVCGGSLISPCWVVSATHCFINYQHKEDYI-VYLGRQPFT 901
R T + CGG+LI PCWV++A HC + K Y+ V LG Q T
Sbjct: 333 LRLTVSTPQGHYCGGALIHPCWVLTAAHC---TEIKTKYLKVVLGDQDLT 379
>ref|NP_776571.2| plasminogen activator, tissue [Bos taurus]
Length = 566
Score = 129 bits (325), Expect = 3e-30
Identities = 70/183 (38%), Positives = 92/183 (50%), Gaps = 2/183 (1%)
Frame = +2
Query: 347 CFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQR 526
C+ GNG +YRG + G CLPWNS + Y A + +A LGLGKHN+CRNPD
Sbjct: 219 CYTGNGLAYRGTRSHTKSGASCLPWNSVFLTSKIYTAWKSNAPALGLGKHNHCRNPDGDA 278
Query: 527 RPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCG-QKALRPRFKI 703
+PWC+V + + C VP C CG ++ RP+F+I
Sbjct: 279 QPWCHVWKDRQLTWEYCDVPQC-----------------------VTCGLRQYKRPQFRI 315
Query: 704 VGGKSTTIENQPWFAAIY-RRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVY 880
GG I + PW AAI+ + R ++CGG LIS CWV+SA HCF V+
Sbjct: 316 KGGLFADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQERYPPLHLKVF 375
Query: 881 LGR 889
LGR
Sbjct: 376 LGR 378
Score = 122 bits (307), Expect = 3e-28
Identities = 53/120 (44%), Positives = 71/120 (59%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
C NGG C Y S+ C CP+ F G+ CEID + TC++ G +YRG +T G C
Sbjct: 92 CFNGGTCRQALYSSDFV-CQCPEGFMGKLCEIDATATCYKDQGVAYRGTWSTAESGAECA 150
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
WNS+ + + Y RP+A++LGLG HNYCRNPD +PWCYV K + + C P C+
Sbjct: 151 NWNSSGLAMKPYSGRRPNAIRLGLGNHNYCRNPDQDSKPWCYVFKAGKYISEFCSTPACA 210
>ref|XP_888406.1| PREDICTED: similar to Coagulation factor XII precursor (Hageman
factor) (HAF) isoform 3 [Bos taurus]
Length = 593
Score = 122 bits (307), Expect = 3e-28
Identities = 76/236 (32%), Positives = 102/236 (43%), Gaps = 18/236 (7%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGN--GHSYRGKANTNTGGRP 409
CLNGG C+ + + C C F G C++D +C++ G SYRG A T G P
Sbjct: 183 CLNGGSCLQAE---GHRLCRCAPSFAGRLCDVDLKASCYDDRDRGLSYRGMAGTTLSGAP 239
Query: 410 CLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPN 589
C W S N L GLG H +CRNPDN RPWC++ G + C +
Sbjct: 240 CQSWASEATYWNVT---AEQVLNWGLGDHAFCRNPDNDTRPWCFIWKGDRLSWNYCRLAP 296
Query: 590 CSGGESH------------RPAYDGKNPF-STPEKVEFQCGQ---KALRPRFKIVGGKST 721
C H +P + P S CGQ K L ++VGG
Sbjct: 297 CQAAAGHEHFPLPSPSALQKPESTTQTPLPSLTSGSPGGCGQRLRKWLSSLNRVVGGLVA 356
Query: 722 TIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLGR 889
P+ AA+Y + C GSLI+PCWV++A HC N ++ V LG+
Sbjct: 357 LPGAHPYIAALYWDQ------HFCAGSLIAPCWVLTAAHCLQNRPAPKELTVVLGQ 406
>ref|XP_875628.1| PREDICTED: similar to Coagulation factor XII precursor (Hageman
factor) (HAF) isoform 2 [Bos taurus]
Length = 605
Score = 118 bits (296), Expect = 6e-27
Identities = 77/248 (31%), Positives = 105/248 (42%), Gaps = 30/248 (12%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGN--GHSYRGKANTNTGGRP 409
CLNGG C+ + + C C F G C++D +C++ G SYRG A T G P
Sbjct: 183 CLNGGSCLQAE---GHRLCRCAPSFAGRLCDVDLKASCYDDRDRGLSYRGMAGTTLSGAP 239
Query: 410 CLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPN 589
C W S N L GLG H +CRNPDN RPWC++ G + C +
Sbjct: 240 CQSWASEATYWNVT---AEQVLNWGLGDHAFCRNPDNDTRPWCFIWKGDRLSWNYCRLAP 296
Query: 590 CSGGESH------------RPAYDGKNPFS---------TPEKVEF----QCGQ---KAL 685
C H +P + P S +P + CGQ K L
Sbjct: 297 CQAAAGHEHFPLPSPSALQKPESTTQTPSSAWAPPTGWCSPTPLASGGPGGCGQRLRKWL 356
Query: 686 RPRFKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKE 865
++VGG P+ AA+Y + C GSLI+PCWV++A HC N +
Sbjct: 357 SSLNRVVGGLVALPGAHPYIAALYWDQ------HFCAGSLIAPCWVLTAAHCLQNRPAPK 410
Query: 866 DYIVYLGR 889
+ V LG+
Sbjct: 411 ELTVVLGQ 418
>ref|XP_588610.2| PREDICTED: similar to Coagulation factor XII precursor (Hageman
factor) (HAF) isoform 1 [Bos taurus]
Length = 603
Score = 118 bits (296), Expect = 6e-27
Identities = 76/246 (30%), Positives = 105/246 (42%), Gaps = 28/246 (11%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGN--GHSYRGKANTNTGGRP 409
CLNGG C+ + + C C F G C++D +C++ G SYRG A T G P
Sbjct: 183 CLNGGSCLQAE---GHRLCRCAPSFAGRLCDVDLKASCYDDRDRGLSYRGMAGTTLSGAP 239
Query: 410 CLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPN 589
C W S N L GLG H +CRNPDN RPWC++ G + C +
Sbjct: 240 CQSWASEATYWNVT---AEQVLNWGLGDHAFCRNPDNDTRPWCFIWKGDRLSWNYCRLAP 296
Query: 590 CSGGESH------------RPAYDGKNP-------FSTPEKVEF----QCGQ---KALRP 691
C H +P + P + +P + CGQ K L
Sbjct: 297 CQAAAGHEHFPLPSPSALQKPESTTQTPLPSLTSGWCSPTPLASGGPGGCGQRLRKWLSS 356
Query: 692 RFKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDY 871
++VGG P+ AA+Y + C GSLI+PCWV++A HC N ++
Sbjct: 357 LNRVVGGLVALPGAHPYIAALYWDQ------HFCAGSLIAPCWVLTAAHCLQNRPAPKEL 410
Query: 872 IVYLGR 889
V LG+
Sbjct: 411 TVVLGQ 416
>ref|XP_888407.1| PREDICTED: similar to Coagulation factor XII precursor (Hageman
factor) (HAF) isoform 4 [Bos taurus]
Length = 610
Score = 116 bits (290), Expect = 3e-26
Identities = 75/253 (29%), Positives = 103/253 (40%), Gaps = 35/253 (13%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGN--GHSYRGKANTNTGGRP 409
CLNGG C+ + + C C F G C++D +C++ G SYRG A T G P
Sbjct: 183 CLNGGSCLQAE---GHRLCRCAPSFAGRLCDVDLKASCYDDRDRGLSYRGMAGTTLSGAP 239
Query: 410 CLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPN 589
C W S N L GLG H +CRNPDN RPWC++ G + C +
Sbjct: 240 CQSWASEATYWNVT---AEQVLNWGLGDHAFCRNPDNDTRPWCFIWKGDRLSWNYCRLAP 296
Query: 590 CSGGESH------------RPAYDGKNPFSTPEKVEFQ------------------CGQ- 676
C H +P + P + + CGQ
Sbjct: 297 CQAAAGHEHFPLPSPSALQKPESTTQTPLPSLTSGTWAPPTGWCSPTPLASGGPGGCGQR 356
Query: 677 --KALRPRFKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFIN 850
K L ++VGG P+ AA+Y + C GSLI+PCWV++A HC N
Sbjct: 357 LRKWLSSLNRVVGGLVALPGAHPYIAALYWDQ------HFCAGSLIAPCWVLTAAHCLQN 410
Query: 851 YQHKEDYIVYLGR 889
++ V LG+
Sbjct: 411 RPAPKELTVVLGQ 423
>ref|XP_580402.2| PREDICTED: similar to HGF activator preproprotein [Bos taurus]
Length = 577
Score = 100 bits (248), Expect = 2e-21
Identities = 72/231 (31%), Positives = 90/231 (38%), Gaps = 10/231 (4%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
CLNGG C + C+CP + G C I +Q CF G G YRG A+T P L
Sbjct: 197 CLNGGSC-HLIVATGTTVCACPPDYAGRLCNIVPAQRCFVGTGTEYRGVASTQASSSPPL 255
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
NPD RPWCYV + C + C
Sbjct: 256 -----------------------------LLNPDKDERPWCYVVKDSALSWEYCRLAACE 286
Query: 596 GGESHRP-----AYDGKNPFSTPEKVEFQCGQK-----ALRPRFKIVGGKSTTIENQPWF 745
+P P + CG++ LRPR I+GG S+ + PW
Sbjct: 287 SLARIQPPPTEALLTLPGPTAAGPAGRQTCGKRHKKRTFLRPR--IIGGSSSLPGSHPWL 344
Query: 746 AAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLGRQPF 898
AAIY + C GSL+ CWVVSA HCF N +E V LG+ F
Sbjct: 345 AAIYIGNN------FCAGSLVHTCWVVSAAHCFSNSPPRESVSVVLGQHFF 389
>ref|NP_776376.1| plasminogen [Bos taurus]
Length = 812
Score = 92.0 bits (227), Expect = 6e-19
Identities = 68/214 (31%), Positives = 88/214 (41%), Gaps = 9/214 (4%)
Frame = +2
Query: 272 FSNIQRCS-----CPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATV 436
F N+++CS P Q E C G G SYRGK T G PC W +
Sbjct: 455 FCNLKKCSETPEQVPAAPQAPGVENPPEADCMIGTGKSYRGKKATTVAGVPCQEWAAQEP 514
Query: 437 LLNTYHAHRPDALQLGLGKHNYCRNPDNQ-RRPWCYVQVGLKQLVQECMVPNCSGGESHR 613
++ + Q GL + NYCRNPD PWCY K C VP C
Sbjct: 515 HQHSIFTPETNP-QSGL-ERNYCRNPDGDVNGPWCYTMNPRKPF-DYCDVPQCESS---- 567
Query: 614 PAYDGKNPFSTPEKVEFQCGQKALRPRF---KIVGGKSTTIENQPWFAAIYRRHRGGSVT 784
F CG+ + P+ +IVGG + + PW ++ R R
Sbjct: 568 ----------------FDCGKPKVEPKKCSGRIVGGCVSKPHSWPWQVSLRRSSR----- 606
Query: 785 YVCGGSLISPCWVVSATHCFINYQHKEDYIVYLG 886
+ CGG+LISP WV++A HC N Y V LG
Sbjct: 607 HFCGGTLISPKWVLTAAHCLDNILALSFYKVILG 640
Score = 66.2 bits (160), Expect = 4e-11
Identities = 46/146 (31%), Positives = 61/146 (41%), Gaps = 4/146 (2%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG ++T GR C W+S T H P+ NYCRNPD
Sbjct: 382 QDCYHGNGQSYRGTSSTTITGRKCQSWSSMT---PHRHLKTPENYPNAGLTMNYCRNPDA 438
Query: 521 QRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQ-KALRPRF 697
+ PWCY + + C + CS PA P + + G K+ R
Sbjct: 439 DKSPWCYT-TDPRVRWEFCNLKKCSETPEQVPAAPQAPGVENPPEADCMIGTGKSYR--- 494
Query: 698 KIVGGKSTTIENQP---WFAAIYRRH 766
G K+TT+ P W A +H
Sbjct: 495 ---GKKATTVAGVPCQEWAAQEPHQH 517
Score = 58.2 bits (139), Expect = 1e-08
Identities = 47/186 (25%), Positives = 66/186 (35%), Gaps = 4/186 (2%)
Frame = +2
Query: 272 FSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTY 451
F +I RC+ P G + C +G G +Y G G C W+ T
Sbjct: 263 FCDIPRCTTPPPSSGPKYQ------CLKGTGKNYGGTVAVTESGHTCQRWSEQTP---HK 313
Query: 452 HAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYD-G 628
H P+ + NYCRNP+ ++ PWCY + + C +P+C D
Sbjct: 314 HNRTPENFPCKNLEENYCRNPNGEKAPWCYT-TNSEVRWEYCTIPSCESSPLSTERMDVP 372
Query: 629 KNPFSTPEKVEFQCGQKALRPRFKIVGGKSTTIEN---QPWFAAIYRRHRGGSVTYVCGG 799
P TP + G G STTI Q W + RH Y G
Sbjct: 373 VPPEQTPVPQDCYHGNGQ-----SYRGTSSTTITGRKCQSWSSMTPHRHLKTPENYPNAG 427
Query: 800 SLISPC 817
++ C
Sbjct: 428 LTMNYC 433
Score = 58.2 bits (139), Expect = 1e-08
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
Frame = +2
Query: 317 EHCEI-DTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGK 493
++C+I + C +G +Y GK GR C W+S + H + P K
Sbjct: 181 DYCDIPECEDKCMHCSGENYEGKIAKTMSGRDCQAWDSQSPHA---HGYIPSKFPNKNLK 237
Query: 494 HNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
NYCRNPD + RPWC+ K+ + C +P C+
Sbjct: 238 MNYCRNPDGEPRPWCFTTDPQKRW-EFCDIPRCT 270
Score = 53.5 bits (127), Expect = 2e-07
Identities = 32/98 (32%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Frame = +2
Query: 347 CFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN-Q 523
C GNG +YRG G C W++ + + + P+ L + NYCRNPDN +
Sbjct: 110 CKTGNGQTYRGTTAETKSGVTCQKWSATSPHVPKF---SPEKFPLAGLEENYCRNPDNDE 166
Query: 524 RRPWCYVQVGLKQLVQECMVPNCSGGESHRPA--YDGK 631
PWCY K+ C +P C H Y+GK
Sbjct: 167 NGPWCYTTDPDKR-YDYCDIPECEDKCMHCSGENYEGK 203
>ref|NP_001026921.1| hepatocyte growth factor [Bos taurus]
Length = 730
Score = 79.7 bits (195), Expect = 3e-15
Identities = 53/190 (27%), Positives = 83/190 (43%), Gaps = 2/190 (1%)
Frame = +2
Query: 323 CEIDTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNY 502
C++ + Q C+ GNG +Y G + G C W+ L+ + PDA +L NY
Sbjct: 383 CDVSSGQDCYRGNGKNYMGSLSKTRSGLTCSMWDKNMEDLHRHIFWEPDATKL---NKNY 439
Query: 503 CRNPDNQRR-PWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQK 679
CRNPD+ PWCY L C + C G + T ++
Sbjct: 440 CRNPDDDAHGPWCYTGNPLIPW-DYCPISRCEGDTT-----------PTIVNLDHPVISC 487
Query: 680 ALRPRFKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCF-INYQ 856
A + ++V G T N W ++ R++ ++CGGSLI W+++A CF +
Sbjct: 488 AKTKQLRVVNGIPTR-TNVGWMVSLKYRNK-----HICGGSLIKESWILTARQCFPSRNK 541
Query: 857 HKEDYIVYLG 886
+DY +LG
Sbjct: 542 DLKDYEAWLG 551
Score = 58.5 bits (140), Expect = 8e-09
Identities = 35/101 (34%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Frame = +2
Query: 347 CFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQR 526
C +G G YRG NT G PC W+S H P+ + + NYCRNPD
Sbjct: 305 CIQGQGEGYRGTINTIWNGIPCQRWDSQ---YPHQHDITPENFKCKDLRENYCRNPDGAE 361
Query: 527 RPWCY-----VQVGLKQLVQECMVPNCSGGESHRPAYDGKN 634
PWC+ ++VG + +C V SG + +R +GKN
Sbjct: 362 SPWCFTTDPNIRVGYCSQIPKCDV--SSGQDCYRG--NGKN 398
Score = 54.7 bits (130), Expect = 1e-07
Identities = 33/106 (31%), Positives = 48/106 (45%), Gaps = 8/106 (7%)
Frame = +2
Query: 332 DTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRN 511
D + C G G SY+G + G C PWNS ++ H+ P + + + NYCRN
Sbjct: 123 DYIRNCIIGKGGSYKGTVSITKSGIKCQPWNS---MIPHEHSFLPSSYRGKDLQENYCRN 179
Query: 512 PDNQR-RPWCYVQVGLKQLVQECMVPNCS-------GGESHRPAYD 625
P + PWC+ + + C +P CS GES+R D
Sbjct: 180 PRGEEGGPWCFTS-NPEVRYEVCDIPQCSEVECMTCNGESYRGPMD 224
Score = 52.0 bits (123), Expect = 7e-07
Identities = 37/121 (30%), Positives = 51/121 (42%), Gaps = 4/121 (3%)
Frame = +2
Query: 317 EHCEID--TSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHR--PDALQLG 484
E C+I + C NG SYRG + G+ C W+ T H H+ P+
Sbjct: 199 EVCDIPQCSEVECMTCNGESYRGPMDHTETGKICQRWDHQTP-----HRHKFLPERYPDK 253
Query: 485 LGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEF 664
NYCRNPD + RPWCY + + C + C +H D P T E ++
Sbjct: 254 GFDDNYCRNPDGKPRPWCYT-LDPDTPWEYCAIKMC----AHSTMNDTDLPMQTTECIQG 308
Query: 665 Q 667
Q
Sbjct: 309 Q 309
Database: RefSeqBP
Posted date: Aug 1, 2006 7:14 PM
Number of letters in database: 16,112,626
Number of sequences in database: 33,508
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,515,987
Number of Sequences: 33508
Number of extensions: 1158142
Number of successful extensions: 5004
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 3907
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4882
length of database: 16,112,626
effective HSP length: 102
effective length of database: 12,694,810
effective search space used: 2830942630
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqCP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-005822
(977 letters)
Database: RefSeqCP
33,732 sequences; 19,266,565 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|XP_536394.2| PREDICTED: similar to urokinase plasminogen act... 429 e-120
Alignment gi|XP_850538.1| PREDICTED: hepatocyte growth factor activator i... 142 5e-34
Alignment gi|XP_861645.1| PREDICTED: hepatocyte growth factor activator i... 142 5e-34
Alignment gi|NP_001026985.1| HGF activator [Canis familiaris] 142 5e-34
Alignment gi|XP_535016.2| PREDICTED: similar to hyaluronan binding protei... 134 1e-31
Alignment gi|XP_539955.2| PREDICTED: similar to Tissue-type plasminogen a... 134 1e-31
Alignment gi|XP_546206.2| PREDICTED: similar to Coagulation factor XII pr... 120 2e-27
Alignment gi|XP_533468.2| PREDICTED: similar to Plasminogen precursor [Ca... 89 6e-18
Alignment gi|NP_001002964.1| hepatocyte growth factor [Canis familiaris] 78 1e-14
Alignment gi|XP_541884.2| PREDICTED: similar to macrophage stimulating 1 ... 71 1e-12
>ref|XP_536394.2| PREDICTED: similar to urokinase plasminogen activator preproprotein
[Canis familiaris]
Length = 543
Score = 429 bits (1102), Expect = e-120
Identities = 205/263 (77%), Positives = 215/263 (81%), Gaps = 1/263 (0%)
Frame = +2
Query: 191 GSHELHQESGASNCGCLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHS 370
GSHE H S ASNC CLNGG CVSYKYFSNIQRC+CPKKFQGEHCEIDTS+TC+EGNGHS
Sbjct: 130 GSHEFHPVSSASNCSCLNGGTCVSYKYFSNIQRCNCPKKFQGEHCEIDTSKTCYEGNGHS 189
Query: 371 YRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQV 550
YRGKANTNT GRPCL WNSA VLL YHA RPDALQLGLGKHNYCRNPD+QR+PWCYVQV
Sbjct: 190 YRGKANTNTRGRPCLAWNSAAVLLKQYHALRPDALQLGLGKHNYCRNPDHQRKPWCYVQV 249
Query: 551 GLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQKALRPRFKIVGGKSTTIE 730
GL QLVQEC V +CS KNP S PEK EFQCGQKALRPRFKI+GG+ TTIE
Sbjct: 250 GLMQLVQECTVQHCS---------FEKNPHSPPEKAEFQCGQKALRPRFKIIGGEFTTIE 300
Query: 731 NQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLGRQPFTPAL 910
NQPWFAAIYR+HRGGSVTY CGGSLISPCWVVSATHCFIN Q K+DYIVYLGR
Sbjct: 301 NQPWFAAIYRKHRGGSVTYQCGGSLISPCWVVSATHCFINSQKKDDYIVYLGRSKRISKT 360
Query: 911 MGR*N*G-GKLILHEDYSADSLA 976
G KLILHEDYSADSLA
Sbjct: 361 FGEMKFEVEKLILHEDYSADSLA 383
>ref|XP_850538.1| PREDICTED: hepatocyte growth factor activator isoform 1 [Canis
familiaris]
Length = 654
Score = 142 bits (358), Expect = 5e-34
Identities = 91/229 (39%), Positives = 108/229 (47%), Gaps = 8/229 (3%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
CLNGG C + CSCP G C I SQ CF GNG YRG A+T G CL
Sbjct: 248 CLNGGTC-HLIVATGTTVCSCPPGHAGRLCNIVPSQRCFVGNGTEYRGVASTAASGLSCL 306
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
WNS + + A LGLG H YCRNPD RPWCYV + C + C
Sbjct: 307 AWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDKDERPWCYVVKDSALSWEYCRLAACE 366
Query: 596 GGESHRPAYDGKNPFSTPEKVEF---QCGQK-----ALRPRFKIVGGKSTTIENQPWFAA 751
+ P+ S E CG++ LRPR I+GG S+ + PW AA
Sbjct: 367 -SLARIPSLTTAVLLSQAEPAPVGRQTCGKRHKKRTFLRPR--IIGGSSSLPGSHPWLAA 423
Query: 752 IYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLGRQPF 898
IY G S C GSL+ CWVVSA HCF N +E +V LG+ F
Sbjct: 424 IY---IGDS---FCAGSLVHTCWVVSAAHCFSNSPRRESVLVVLGQHFF 466
>ref|XP_861645.1| PREDICTED: hepatocyte growth factor activator isoform 2 [Canis
familiaris]
Length = 657
Score = 142 bits (358), Expect = 5e-34
Identities = 91/229 (39%), Positives = 108/229 (47%), Gaps = 8/229 (3%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
CLNGG C + CSCP G C I SQ CF GNG YRG A+T G CL
Sbjct: 251 CLNGGTC-HLIVATGTTVCSCPPGHAGRLCNIVPSQRCFVGNGTEYRGVASTAASGLSCL 309
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
WNS + + A LGLG H YCRNPD RPWCYV + C + C
Sbjct: 310 AWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDKDERPWCYVVKDSALSWEYCRLAACE 369
Query: 596 GGESHRPAYDGKNPFSTPEKVEF---QCGQK-----ALRPRFKIVGGKSTTIENQPWFAA 751
+ P+ S E CG++ LRPR I+GG S+ + PW AA
Sbjct: 370 -SLARIPSLTTAVLLSQAEPAPVGRQTCGKRHKKRTFLRPR--IIGGSSSLPGSHPWLAA 426
Query: 752 IYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLGRQPF 898
IY G S C GSL+ CWVVSA HCF N +E +V LG+ F
Sbjct: 427 IY---IGDS---FCAGSLVHTCWVVSAAHCFSNSPRRESVLVVLGQHFF 469
>ref|NP_001026985.1| HGF activator [Canis familiaris]
Length = 654
Score = 142 bits (358), Expect = 5e-34
Identities = 91/229 (39%), Positives = 108/229 (47%), Gaps = 8/229 (3%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
CLNGG C + CSCP G C I SQ CF GNG YRG A+T G CL
Sbjct: 248 CLNGGTC-HLIVATGTTVCSCPPGHAGRLCNIVPSQRCFVGNGTEYRGVASTAASGLSCL 306
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
WNS + + A LGLG H YCRNPD RPWCYV + C + C
Sbjct: 307 AWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDKDERPWCYVVKDSALSWEYCRLAACE 366
Query: 596 GGESHRPAYDGKNPFSTPEKVEF---QCGQK-----ALRPRFKIVGGKSTTIENQPWFAA 751
+ P+ S E CG++ LRPR I+GG S+ + PW AA
Sbjct: 367 -SLARIPSLTTAVLLSQAEPAPVGRQTCGKRHKKRTFLRPR--IIGGSSSLPGSHPWLAA 423
Query: 752 IYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLGRQPF 898
IY G S C GSL+ CWVVSA HCF N +E +V LG+ F
Sbjct: 424 IY---IGDS---FCAGSLVHTCWVVSAAHCFSNSPRRESVLVVLGQHFF 466
>ref|XP_535016.2| PREDICTED: similar to hyaluronan binding protein 2 [Canis
familiaris]
Length = 565
Score = 134 bits (338), Expect = 1e-31
Identities = 73/207 (35%), Positives = 106/207 (51%), Gaps = 5/207 (2%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
C NGG C + S C+CP +F+G+ CEI C+ G+G+SYRGK + CL
Sbjct: 165 CQNGGTCSRQRRRSKFT-CTCPDQFKGKFCEIGPDD-CYVGDGYSYRGKVSKTVNQHSCL 222
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQE-CMVPNC 592
WNS +L Y+ DA G+G+HN+CRNPD ++PWC+++ +L E C V C
Sbjct: 223 YWNSHLLLHENYNIFMEDAEAHGIGEHNFCRNPDGDKKPWCFIKANNAKLKWEYCDVSAC 282
Query: 593 SGGESHRPAYDGKNPFSTPEKVEFQCGQKALRPRFK-IVGGKSTTIENQPWFAAIYRR-- 763
S + P P + + CG+ + + K I GG +T PW A++
Sbjct: 283 SALDIADPEGSLTEPLTKLPGFD-SCGRTEMTKKVKRIYGGFKSTAGKHPWQASLQTSLP 341
Query: 764 -HRGGSVTYVCGGSLISPCWVVSATHC 841
+ CGG+LI PCWV++A HC
Sbjct: 342 LTVSMPQGHFCGGALIHPCWVLTAAHC 368
>ref|XP_539955.2| PREDICTED: similar to Tissue-type plasminogen activator precursor
(tPA) (t-PA) (t-plasminogen activator) [Canis
familiaris]
Length = 560
Score = 134 bits (338), Expect = 1e-31
Identities = 75/202 (37%), Positives = 96/202 (47%), Gaps = 2/202 (0%)
Frame = +2
Query: 290 CSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPD 469
CS P C + ++ C+ G G +YRG + T G PCLPWNS + Y + +
Sbjct: 200 CSTPA------CPKEKNEDCYFGKGLAYRGTYSFTTSGTPCLPWNSRVLAGKFYTTWKTN 253
Query: 470 ALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTP 649
A LGLG HNYCRNPD +PWC+V K + C VP CS
Sbjct: 254 AQALGLGSHNYCRNPDGDAKPWCHVLKDRKLTWEYCDVPQCS------------------ 295
Query: 650 EKVEFQCGQKALR-PRFKIVGGKSTTIENQPWFAAIY-RRHRGGSVTYVCGGSLISPCWV 823
CG + + P+F+I GG I + PW AAI+ + R + CGG LIS CWV
Sbjct: 296 -----TCGLRHYKQPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFFCGGILISSCWV 350
Query: 824 VSATHCFINYQHKEDYIVYLGR 889
+SA HCF V LGR
Sbjct: 351 LSAAHCFQERYPPHQLKVVLGR 372
Score = 131 bits (329), Expect = 1e-30
Identities = 63/138 (45%), Positives = 76/138 (55%)
Frame = +2
Query: 218 GASNCGCLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNT 397
G S C NGG C YF++ C CP+ F G+ CEID TC++ G SYRG +T
Sbjct: 82 GCSEPRCFNGGTCRQALYFADFV-CQCPEGFLGKRCEIDAGATCYKDQGISYRGTWSTAE 140
Query: 398 GGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQEC 577
G C WNS+ + L Y A RP A++LGLG HNYCRNPD RPWCYV K + C
Sbjct: 141 SGAECANWNSSALALKPYSARRPHAVRLGLGSHNYCRNPDGDLRPWCYVFKAGKYSTEFC 200
Query: 578 MVPNCSGGESHRPAYDGK 631
P C E + Y GK
Sbjct: 201 STPACP-KEKNEDCYFGK 217
>ref|XP_546206.2| PREDICTED: similar to Coagulation factor XII precursor (Hageman
factor) (HAF) [Canis familiaris]
Length = 611
Score = 120 bits (301), Expect = 2e-27
Identities = 80/263 (30%), Positives = 108/263 (41%), Gaps = 33/263 (12%)
Frame = +2
Query: 200 ELHQESGASNCGCLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRG 379
+L G CLNGG C + + C CP + G C++DT C+ G G YRG
Sbjct: 171 KLVASQGCHTNPCLNGGTCFQAETH---RLCRCPTGYAGRFCDVDTGARCYHGRGLDYRG 227
Query: 380 KANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLK 559
A+ G C W S + AL GLG H +CRNPDN RPWC+V+ G +
Sbjct: 228 AADAALSGARCQRWASEA---SYQEVPAEQALSWGLGNHAFCRNPDNDTRPWCFVRSGDR 284
Query: 560 QLVQECMVPNCSGG-------------ESHRPAYDGKNPFS-------TPEK-------- 655
+ C + C S RP +P + TP
Sbjct: 285 LSWEYCRLARCQAPGLAIPQILPPTQVPSGRPTLPVPSPSALQKPQPPTPASSATREQPA 344
Query: 656 --VEFQCGQ---KALRPRFKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCW 820
+CGQ K L ++VGG P+ AA+Y RH C GSLI+ CW
Sbjct: 345 AVPSSRCGQRLRKRLSSLSRVVGGLVALPGAHPYIAALYWRHS------FCAGSLIASCW 398
Query: 821 VVSATHCFINYQHKEDYIVYLGR 889
V++A HC + + V LG+
Sbjct: 399 VLTAAHCLQDRPAPGELTVVLGQ 421
>ref|XP_533468.2| PREDICTED: similar to Plasminogen precursor [Canis familiaris]
Length = 812
Score = 89.0 bits (219), Expect = 6e-18
Identities = 64/217 (29%), Positives = 91/217 (41%), Gaps = 12/217 (5%)
Frame = +2
Query: 272 FSNIQRCSCPKKF--------QGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCLPWNS 427
F N+++C P+ Q + ++ C GNG YRGK T G PC W +
Sbjct: 450 FCNLRKCLDPEASATNSPAVPQVPSGQEPSASDCMFGNGKGYRGKKATTVMGIPCQEWAA 509
Query: 428 ATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQ-RRPWCYVQVGLKQLVQECMVPNCSGGE 604
++ + Q GL K NYCRNPD PWCY + ++L C VP C
Sbjct: 510 QEPHRHSIFTPETNP-QAGLEK-NYCRNPDGDVNGPWCYT-MNQRKLFDYCDVPQCVS-- 564
Query: 605 SHRPAYDGKNPFSTPEKVEFQCGQKALRPRF---KIVGGKSTTIENQPWFAAIYRRHRGG 775
F CG+ + P+ ++VGG + PW ++ R+
Sbjct: 565 -----------------TSFDCGKPQVEPKKCPGRVVGGCVANPHSWPWQISLRTRYG-- 605
Query: 776 SVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLG 886
+ CGG+LISP WV++A HC Y V LG
Sbjct: 606 --KHFCGGTLISPEWVLTAAHCLERSSRPASYKVILG 640
Score = 65.5 bits (158), Expect = 8e-11
Identities = 34/107 (31%), Positives = 46/107 (42%)
Frame = +2
Query: 272 FSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTY 451
F +I RC+ P G + C +G G SYRGK + G C W+ T
Sbjct: 256 FCDIPRCTTPPPPSGP------TYQCLKGRGESYRGKVSVTVSGHTCQHWSEQTP---HK 306
Query: 452 HAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNC 592
H P+ NYCRNPD + PWCY + + C +P+C
Sbjct: 307 HNRTPENFPCKNLDENYCRNPDGETAPWCYT-TNSEVRWEHCQIPSC 352
Score = 63.2 bits (152), Expect = 4e-10
Identities = 48/150 (32%), Positives = 62/150 (41%), Gaps = 8/150 (5%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG ++T GR C W+S T H P+ NYCRNPD
Sbjct: 377 QECYHGNGQSYRGTSSTTITGRKCQSWSSMT---PHRHEKTPEHFPEAGLTMNYCRNPDA 433
Query: 521 QRRPWCYVQVGLKQL----VQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQ-KAL 685
+ PWCY + +++C+ P S S PA P + G K
Sbjct: 434 DKSPWCYTTDPSVRWEFCNLRKCLDPEASATNS--PAVPQVPSGQEPSASDCMFGNGKGY 491
Query: 686 RPRFKIVGGKSTTIEN---QPWFAAIYRRH 766
R G K+TT+ Q W A RH
Sbjct: 492 R------GKKATTVMGIPCQEWAAQEPHRH 515
Score = 60.5 bits (145), Expect = 2e-09
Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Frame = +2
Query: 317 EHCEI-DTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGK 493
++C I + + C +G +Y GK + G C WNS T + Y + + L K
Sbjct: 174 DYCNIPECEEECMHCSGENYEGKISKTKSGLECQAWNSQTPHAHGYIPSKFPSKNL---K 230
Query: 494 HNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
NYCRNPD + RPWC+ K+ + C +P C+
Sbjct: 231 MNYCRNPDGEPRPWCFTMDPNKRW-EFCDIPRCT 263
>ref|NP_001002964.1| hepatocyte growth factor [Canis familiaris]
Length = 730
Score = 78.2 bits (191), Expect = 1e-14
Identities = 53/190 (27%), Positives = 82/190 (43%), Gaps = 2/190 (1%)
Frame = +2
Query: 323 CEIDTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNY 502
C++ + Q C+ GNG +Y G + G C W L+ + PDA +L NY
Sbjct: 383 CDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWEKNMEDLHRHIFWEPDASKL---NKNY 439
Query: 503 CRNPDNQRR-PWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQK 679
CRNPD+ PWCY L C + C G + T ++
Sbjct: 440 CRNPDDDAHGPWCYTGNPLIPW-DYCPIFRCEGDTT-----------PTIVNLDHPVISC 487
Query: 680 ALRPRFKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQH 859
A + ++V G T N W ++ R++ ++CGGSLI W+++A CF +
Sbjct: 488 AKTKQLRVVNGIPTR-TNVGWMVSLKYRNK-----HICGGSLIKESWILTARQCFPSRNR 541
Query: 860 K-EDYIVYLG 886
+DY +LG
Sbjct: 542 DLKDYEAWLG 551
Score = 58.5 bits (140), Expect = 9e-09
Identities = 35/101 (34%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Frame = +2
Query: 347 CFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQR 526
C +G G YRG NT G PC W+S H P+ + + NYCRNPD
Sbjct: 305 CIQGQGEGYRGTINTIWNGVPCQRWDSQ---YPHQHDITPENFKCKDLRENYCRNPDGAE 361
Query: 527 RPWCY-----VQVGLKQLVQECMVPNCSGGESHRPAYDGKN 634
PWC+ ++VG + +C V SG + +R +GKN
Sbjct: 362 SPWCFTTDPNIRVGYCSQIPKCDV--SSGQDCYRG--NGKN 398
Score = 54.7 bits (130), Expect = 1e-07
Identities = 33/106 (31%), Positives = 48/106 (45%), Gaps = 8/106 (7%)
Frame = +2
Query: 332 DTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRN 511
D + C G G SY+G + G C PWNS ++ H+ P + + + NYCRN
Sbjct: 123 DYIRNCIIGKGGSYKGTVSITKSGIKCQPWNS---MIPHEHSFLPSSYRGKDLQENYCRN 179
Query: 512 PDNQR-RPWCYVQVGLKQLVQECMVPNCS-------GGESHRPAYD 625
P + PWC+ + + C +P CS GES+R D
Sbjct: 180 PRGEEGGPWCFTS-NPEVRYEVCDIPQCSEVECMTCNGESYRGPMD 224
Score = 52.8 bits (125), Expect = 5e-07
Identities = 37/121 (30%), Positives = 51/121 (42%), Gaps = 4/121 (3%)
Frame = +2
Query: 317 EHCEID--TSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHR--PDALQLG 484
E C+I + C NG SYRG + G+ C W+ T H H+ P+
Sbjct: 199 EVCDIPQCSEVECMTCNGESYRGPMDHTESGKICQRWDHQTP-----HRHKFLPERYPDK 253
Query: 485 LGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEF 664
NYCRNPD + RPWCY + + C + C +H D P T E ++
Sbjct: 254 GFDDNYCRNPDGKPRPWCYT-LDPDTPWEYCAIKMC----AHSTMNDTDVPMETTECIQG 308
Query: 665 Q 667
Q
Sbjct: 309 Q 309
>ref|XP_541884.2| PREDICTED: similar to macrophage stimulating 1 (hepatocyte growth
factor-like) [Canis familiaris]
Length = 712
Score = 71.2 bits (173), Expect = 1e-12
Identities = 62/216 (28%), Positives = 93/216 (43%), Gaps = 15/216 (6%)
Frame = +2
Query: 308 FQGEHCEIDTS-QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHA-HRPDALQL 481
+Q C D + C+ G G YRG + G PC W++ + A PDA
Sbjct: 357 YQIPRCADDVRPEDCYNGVGERYRGSVSRTRKGVPCQHWSAEMPHKPQFTAISAPDAHL- 415
Query: 482 GLGKHNYCRNPDNQRR-PWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKV 658
+ N+CRNPD PWCY C + C + + P++V
Sbjct: 416 ---EENFCRNPDRDSHGPWCYT-TDPGTPFDYCALRRCDDDQP-------PSILEPPDQV 464
Query: 659 EFQ-CGQKALR-----PRFKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCW 820
F+ CG++ R + ++VGG+ N PW ++ R+R G + CGGSL+ W
Sbjct: 465 VFEKCGKRVTRLDQQRSKLRVVGGQPG---NSPWTVSL--RNRQGQ--HFCGGSLVKEQW 517
Query: 821 VVSATHCFIN-YQHKEDYIVYLGR-----QPFTPAL 910
V++A CF + + Y V+LG QP P L
Sbjct: 518 VLTARQCFSSCHVPLMGYEVWLGTLFQNPQPGEPGL 553
Score = 65.9 bits (159), Expect = 6e-11
Identities = 36/121 (29%), Positives = 52/121 (42%), Gaps = 2/121 (1%)
Frame = +2
Query: 272 FSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTY 451
F ++ RC + + E T+ CF G G YRG ANT G PC W++
Sbjct: 263 FCDLTRCGSEAQPRHE----STTLNCFRGKGEGYRGTANTTAAGVPCQRWDA-----QKP 313
Query: 452 HAHR--PDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYD 625
H HR P+ + N+CRNPD PWC+ ++ +P C+ Y+
Sbjct: 314 HQHRFAPEKYACKDLRENFCRNPDGSEAPWCFTSRPGMRVAFCYQIPRCADDVRPEDCYN 373
Query: 626 G 628
G
Sbjct: 374 G 374
Score = 56.6 bits (135), Expect = 4e-08
Identities = 39/114 (34%), Positives = 52/114 (45%), Gaps = 12/114 (10%)
Frame = +2
Query: 320 HCEI----DTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGL 487
HC++ D +TC NG YRG TGG PC W+ H + P L+ GL
Sbjct: 98 HCDLFQKKDYVRTCITDNGVKYRGTVAITTGGLPCQHWSHR---FPNDHKYTP-TLRNGL 153
Query: 488 GKHNYCRNPD-NQRRPWCYVQVGLKQLVQECMVPNC-------SGGESHRPAYD 625
+ N+CRNPD + PWCY + Q C + +C GE +R A D
Sbjct: 154 -EENFCRNPDRDPGGPWCYTTDPAVRF-QSCGIKSCREAACVWCNGEDYRGAVD 205
Score = 50.4 bits (119), Expect = 3e-06
Identities = 29/68 (42%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Frame = +2
Query: 347 CFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKH---NYCRNPD 517
C NG YRG + GR C W+ L HAH P L K NYCRNPD
Sbjct: 192 CVWCNGEDYRGAVDRTQSGRECQRWD-----LQHPHAH-PFEPGKFLDKDLDDNYCRNPD 245
Query: 518 NQRRPWCY 541
RPWCY
Sbjct: 246 GSERPWCY 253
Database: RefSeqCP
Posted date: Aug 1, 2006 9:25 PM
Number of letters in database: 19,266,565
Number of sequences in database: 33,732
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,227,170
Number of Sequences: 33732
Number of extensions: 1351159
Number of successful extensions: 6087
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 4547
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5925
length of database: 19,266,565
effective HSP length: 103
effective length of database: 15,792,169
effective search space used: 3505861518
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqHP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-005822
(977 letters)
Database: RefSeqHP
39,411 sequences; 17,774,539 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_002649.1| urokinase plasminogen activator preproprotein [... 415 e-116
Alignment gi|NP_001519.1| HGF activator preproprotein [Homo sapiens] 142 3e-34
Alignment gi|NP_127509.1| plasminogen activator, tissue type isoform 3 pr... 141 1e-33
Alignment gi|NP_000921.1| plasminogen activator, tissue type isoform 1 pr... 141 1e-33
Alignment gi|NP_004123.1| hyaluronan binding protein 2 [Homo sapiens] 137 2e-32
Alignment gi|NP_000922.2| plasminogen activator, tissue type isoform 2 pr... 133 2e-31
Alignment gi|NP_000496.1| coagulation factor XII precursor [Homo sapiens] 129 3e-30
Alignment gi|NP_005568.1| lipoprotein, Lp(a) [Homo sapiens] 89 4e-18
Alignment gi|XP_946885.1| PREDICTED: similar to Apolipoprotein(a) precurs... 89 4e-18
Alignment gi|XP_931416.1| PREDICTED: similar to Apolipoprotein(a) precurs... 89 4e-18
>ref|NP_002649.1| urokinase plasminogen activator preproprotein [Homo sapiens]
Length = 431
Score = 415 bits (1066), Expect = e-116
Identities = 198/267 (74%), Positives = 217/267 (81%), Gaps = 1/267 (0%)
Frame = +2
Query: 179 SDSKGSHELHQESGASNCGCLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEG 358
SDSKGS+ELHQ SNC CLNGG CVS KYFSNI C+CPKKF G+HCEID S+TC+EG
Sbjct: 16 SDSKGSNELHQVP--SNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTCYEG 73
Query: 359 NGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWC 538
NGH YRGKA+T+T GRPCLPWNSATVL TYHAHR DALQLGLGKHNYCRNPDN+RRPWC
Sbjct: 74 NGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWC 133
Query: 539 YVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQKALRPRFKIVGGKS 718
YVQVGLK LVQECMV +C+ DGK P S PE+++FQCGQK LRPRFKI+GG+
Sbjct: 134 YVQVGLKPLVQECMVHDCA---------DGKKPSSPPEELKFQCGQKTLRPRFKIIGGEF 184
Query: 719 TTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLGRQPF 898
TTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWV+SATHCFI+Y KEDYIVYLGR
Sbjct: 185 TTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRL 244
Query: 899 TPALMGR*N*G-GKLILHEDYSADSLA 976
G LILH+DYSAD+LA
Sbjct: 245 NSNTQGEMKFEVENLILHKDYSADTLA 271
>ref|NP_001519.1| HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 142 bits (359), Expect = 3e-34
Identities = 88/227 (38%), Positives = 110/227 (48%), Gaps = 6/227 (2%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
CLNGG C + C+CP F G C I+ + CF GNG YRG A+T+ G CL
Sbjct: 250 CLNGGTC-HLIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCL 308
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
WNS + + A LGLG H YCRNPDN RPWCYV + C + C
Sbjct: 309 AWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACE 368
Query: 596 GGESHRPAYDGKNPFSTPEKVEFQ-CGQK-----ALRPRFKIVGGKSTTIENQPWFAAIY 757
+ + D P Q CG++ LRPR I+GG S+ + PW AAIY
Sbjct: 369 SLTRVQLSPDLLATLPEPASPGRQACGRRHKKRTFLRPR--IIGGSSSLPGSHPWLAAIY 426
Query: 758 RRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLGRQPF 898
G S C GSL+ CWVVSA HCF + ++ V LG+ F
Sbjct: 427 ---IGDS---FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFF 467
>ref|NP_127509.1| plasminogen activator, tissue type isoform 3 precursor [Homo
sapiens]
Length = 516
Score = 141 bits (355), Expect = 1e-33
Identities = 75/201 (37%), Positives = 100/201 (49%), Gaps = 6/201 (2%)
Frame = +2
Query: 305 KFQGEHCEI----DTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDA 472
K+ E C + + C+ GNG +YRG + G CLPWNS ++ Y A P A
Sbjct: 151 KYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSA 210
Query: 473 LQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPE 652
LGLGKHNYCRNPD +PWC+V + + C VP+CS
Sbjct: 211 QALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCS------------------- 251
Query: 653 KVEFQCG-QKALRPRFKIVGGKSTTIENQPWFAAIYRRH-RGGSVTYVCGGSLISPCWVV 826
CG ++ +P+F+I GG I + PW AAI+ +H R ++CGG LIS CW++
Sbjct: 252 ----TCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWIL 307
Query: 827 SATHCFINYQHKEDYIVYLGR 889
SA HCF V LGR
Sbjct: 308 SAAHCFQERFPPHHLTVILGR 328
Score = 135 bits (340), Expect = 5e-32
Identities = 63/130 (48%), Positives = 74/130 (56%)
Frame = +2
Query: 218 GASNCGCLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNT 397
G S C NGG C YFS+ C CP+ F G+ CEIDT TC+E G SYRG +T
Sbjct: 39 GCSEPRCFNGGTCQQALYFSDFV-CQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAE 97
Query: 398 GGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQEC 577
G C WNS+ + Y RPDA++LGLG HNYCRNPD +PWCYV K + C
Sbjct: 98 SGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFC 157
Query: 578 MVPNCSGGES 607
P CS G S
Sbjct: 158 STPACSEGNS 167
>ref|NP_000921.1| plasminogen activator, tissue type isoform 1 preproprotein [Homo
sapiens]
Length = 562
Score = 141 bits (355), Expect = 1e-33
Identities = 75/201 (37%), Positives = 100/201 (49%), Gaps = 6/201 (2%)
Frame = +2
Query: 305 KFQGEHCEI----DTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDA 472
K+ E C + + C+ GNG +YRG + G CLPWNS ++ Y A P A
Sbjct: 197 KYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSA 256
Query: 473 LQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPE 652
LGLGKHNYCRNPD +PWC+V + + C VP+CS
Sbjct: 257 QALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCS------------------- 297
Query: 653 KVEFQCG-QKALRPRFKIVGGKSTTIENQPWFAAIYRRH-RGGSVTYVCGGSLISPCWVV 826
CG ++ +P+F+I GG I + PW AAI+ +H R ++CGG LIS CW++
Sbjct: 298 ----TCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWIL 353
Query: 827 SATHCFINYQHKEDYIVYLGR 889
SA HCF V LGR
Sbjct: 354 SAAHCFQERFPPHHLTVILGR 374
Score = 133 bits (335), Expect = 2e-31
Identities = 61/124 (49%), Positives = 72/124 (58%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
C NGG C YFS+ C CP+ F G+ CEIDT TC+E G SYRG +T G C
Sbjct: 91 CFNGGTCQQALYFSDFV-CQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAECT 149
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
WNS+ + Y RPDA++LGLG HNYCRNPD +PWCYV K + C P CS
Sbjct: 150 NWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPACS 209
Query: 596 GGES 607
G S
Sbjct: 210 EGNS 213
>ref|NP_004123.1| hyaluronan binding protein 2 [Homo sapiens]
Length = 560
Score = 137 bits (344), Expect = 2e-32
Identities = 77/208 (37%), Positives = 107/208 (51%), Gaps = 6/208 (2%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
C NG C +K S C+CP +F+G+ CEI S C+ G+G+SYRGK N CL
Sbjct: 159 CQNGATCSRHKRRSKFT-CACPDQFKGKFCEIG-SDDCYVGDGYSYRGKMNRTVNQHACL 216
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQE-CMVPNC 592
WNS +L Y+ DA G+G+HN+CRNPD +PWC+++V ++ E C V C
Sbjct: 217 YWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDVSAC 276
Query: 593 SGGESHRPAYDGKNPFSTPEKVEFQCGQKALRPR--FKIVGGKSTTIENQPWFAAIYRR- 763
S + P P ST CG+ + R +I GG +T PW A++
Sbjct: 277 SAQDVAYPEESPTEP-STKLPGFDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSL 335
Query: 764 --HRGGSVTYVCGGSLISPCWVVSATHC 841
+ CGG+LI PCWV++A HC
Sbjct: 336 PLTISMPQGHFCGGALIHPCWVLTAAHC 363
>ref|NP_000922.2| plasminogen activator, tissue type isoform 2 precursor [Homo
sapiens]
Length = 291
Score = 133 bits (335), Expect = 2e-31
Identities = 61/124 (49%), Positives = 72/124 (58%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
C NGG C YFS+ C CP+ F G+ CEIDT TC+E G SYRG +T G C
Sbjct: 91 CFNGGTCQQALYFSDFV-CQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAECT 149
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
WNS+ + Y RPDA++LGLG HNYCRNPD +PWCYV K + C P CS
Sbjct: 150 NWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPACS 209
Query: 596 GGES 607
G S
Sbjct: 210 EGNS 213
Score = 68.2 bits (165), Expect = 1e-11
Identities = 31/72 (43%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Frame = +2
Query: 305 KFQGEHCEI----DTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDA 472
K+ E C + + C+ GNG +YRG + G CLPWNS ++ Y A P A
Sbjct: 197 KYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSA 256
Query: 473 LQLGLGKHNYCR 508
LGLGKHNYCR
Sbjct: 257 QALGLGKHNYCR 268
>ref|NP_000496.1| coagulation factor XII precursor [Homo sapiens]
Length = 615
Score = 129 bits (325), Expect = 3e-30
Identities = 81/260 (31%), Positives = 110/260 (42%), Gaps = 41/260 (15%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
CL+GG+C+ + + C CP + G C++DT +C++G G SYRG A T G PC
Sbjct: 183 CLHGGRCLEVE---GHRLCHCPVGYTGPFCDVDTKASCYDGRGLSYRGLARTTLSGAPCQ 239
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
PW S N A GLG H +CRNPDN RPWC+V + + C + C
Sbjct: 240 PWASEATYRNVT---AEQARNWGLGGHAFCRNPDNDIRPWCFVLNRDRLSWEYCDLAQCQ 296
Query: 596 GGESHRPAY----------------------------DGKNPFSTPEKVE---------- 661
P + P + P K E
Sbjct: 297 TPTQAAPPTPVSPRLHVPLMPAQPAPPKPQPTTRTPPQSQTPGALPAKREQPPSLTRNGP 356
Query: 662 FQCGQ---KALRPRFKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSA 832
CGQ K+L ++VGG P+ AA+Y H C GSLI+PCWV++A
Sbjct: 357 LSCGQRLRKSLSSMTRVVGGLVALRGAHPYIAALYWGHS------FCAGSLIAPCWVLTA 410
Query: 833 THCFINYQHKEDYIVYLGRQ 892
HC + ED V LG++
Sbjct: 411 AHCLQDRPAPEDLTVVLGQE 430
>ref|NP_005568.1| lipoprotein, Lp(a) [Homo sapiens]
Length = 4548
Score = 89.4 bits (220), Expect = 4e-18
Identities = 68/222 (30%), Positives = 87/222 (39%), Gaps = 17/222 (7%)
Frame = +2
Query: 272 FSNIQRCSC--------PKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCLPWNS 427
+ N+ RCS P Q + Q C GNG YRGK T G PC W +
Sbjct: 4195 YCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQEWAA 4254
Query: 428 ATVLLNTYHAHRPDALQLGLGK-----HNYCRNPDNQ-RRPWCYVQVGLKQLVQECMVPN 589
HR G K NYCRNPD PWCY + ++L C +P
Sbjct: 4255 Q-------EPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYT-MNPRKLFDYCDIPL 4306
Query: 590 CSGGESHRPAYDGKNPFSTPEKVEFQCGQKALRPRF---KIVGGKSTTIENQPWFAAIYR 760
C+ F CG+ + P+ IVGG + PW ++
Sbjct: 4307 CASSS-------------------FDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSL-- 4345
Query: 761 RHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLG 886
R R G + CGG+LISP WV++A HC Y V LG
Sbjct: 4346 RTRFGK--HFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILG 4385
Score = 65.1 bits (157), Expect = 9e-11
Identities = 32/89 (35%), Positives = 47/89 (52%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ G+G SYRG ++T GR C W+S ++ +H P+ NYCRNPD+
Sbjct: 4008 QDCYHGDGRSYRGISSTTVTGRTCQSWSS---MIPHWHQRTPENYPNAGLTENYCRNPDS 4064
Query: 521 QRRPWCYVQVGLKQLVQECMVPNCSGGES 607
++PWCY + + C + CS ES
Sbjct: 4065 GKQPWCYTTDPCVRW-EYCNLTQCSETES 4092
Score = 64.3 bits (155), Expect = 1e-10
Identities = 30/69 (43%), Positives = 37/69 (53%)
Frame = +2
Query: 335 TSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNP 514
T Q C+ G+G SYRG +T GR C W+S T +H + G NYCRNP
Sbjct: 3778 TVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMT---PHWHQRTTEYYPNGGLTRNYCRNP 3834
Query: 515 DNQRRPWCY 541
D + RPWCY
Sbjct: 3835 DAEIRPWCY 3843
Score = 62.8 bits (151), Expect = 4e-10
Identities = 33/70 (47%), Positives = 39/70 (55%), Gaps = 3/70 (4%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDAL---QLGLGKHNYCRN 511
Q C+ G+G SYRG +T GR C W+S T H HR L GL + NYCRN
Sbjct: 3894 QDCYRGDGQSYRGTLSTTITGRTCQSWSSMTP-----HWHRRIPLYYPNAGLTR-NYCRN 3947
Query: 512 PDNQRRPWCY 541
PD + RPWCY
Sbjct: 3948 PDAEIRPWCY 3957
Score = 60.8 bits (146), Expect = 2e-09
Identities = 28/67 (41%), Positives = 35/67 (52%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ G+G SYRG +T GR C W+S T +H + G NYCRNPD
Sbjct: 3674 QDCYHGDGQSYRGSFSTTVTGRTCQSWSSMT---PHWHQRTTEYYPNGGLTRNYCRNPDA 3730
Query: 521 QRRPWCY 541
+ PWCY
Sbjct: 3731 EISPWCY 3737
Score = 59.3 bits (142), Expect = 5e-09
Identities = 40/120 (33%), Positives = 49/120 (40%), Gaps = 18/120 (15%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCS------------CPKKFQGEHCEI-DTSQT-----CFEGN 361
C CV ++Y N+ +CS P H E T QT C+ GN
Sbjct: 4070 CYTTDPCVRWEY-CNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHGN 4128
Query: 362 GHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCY 541
G SYRG +T GR C W+S T H P+ NYCRNPD PWC+
Sbjct: 4129 GQSYRGTFSTTVTGRTCQSWSSMT---PHRHQRTPENYPNDGLTMNYCRNPDADTGPWCF 4185
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 3218 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 3274
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 3275 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 3301
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 3104 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 3160
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 3161 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 3187
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 2990 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 3046
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 3047 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 3073
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 2876 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 2932
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 2933 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 2959
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 2762 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 2818
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 2819 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 2845
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 2648 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 2704
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 2705 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 2731
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 2534 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 2590
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 2591 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 2617
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 2420 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 2476
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 2477 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 2503
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 2306 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 2362
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 2363 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 2389
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 2192 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 2248
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 2249 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 2275
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 2078 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 2134
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 2135 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 2161
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 1964 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 2020
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 2021 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 2047
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 1850 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 1906
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 1907 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 1933
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 1736 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 1792
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 1793 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 1819
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 1622 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 1678
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 1679 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 1705
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 1508 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 1564
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 1565 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 1591
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 1394 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 1450
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 1451 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 1477
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 1280 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 1336
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 1337 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 1363
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 1166 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 1222
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 1223 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 1249
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 1052 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 1108
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 1109 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 1135
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 938 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 994
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 995 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 1021
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 824 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 880
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 881 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 907
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 710 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 766
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 767 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 793
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 596 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 652
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 653 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 679
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 482 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 538
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 539 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 565
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 368 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 424
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 425 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 451
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 254 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 310
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 311 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 337
Score = 58.5 bits (140), Expect = 8e-09
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 140 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDA 196
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 197 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 223
Score = 58.2 bits (139), Expect = 1e-08
Identities = 28/67 (41%), Positives = 34/67 (50%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ G SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 3560 QDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTP---HQHSRTPENYPNAGLTRNYCRNPDA 3616
Query: 521 QRRPWCY 541
+ RPWCY
Sbjct: 3617 EIRPWCY 3623
Score = 57.8 bits (138), Expect = 1e-08
Identities = 32/88 (36%), Positives = 42/88 (47%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ GNG SYRG +T GR C W+S T H+ P+ NYCRNPD
Sbjct: 3332 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMT---PHSHSRTPEYYPNAGLIMNYCRNPDP 3388
Query: 521 QRRPWCYVQVGLKQLVQECMVPNCSGGE 604
P+CY + + + C + CS E
Sbjct: 3389 VAAPYCYTRDPSVRW-EYCNLTQCSDAE 3415
Score = 56.2 bits (134), Expect = 4e-08
Identities = 35/89 (39%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNT-YHAHRPDALQLGLGKHNYCRNPD 517
Q C+ GNG SY+G GR C W+S T ++ A+ P+A GL K NYCRNPD
Sbjct: 3446 QECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNA---GLIK-NYCRNPD 3501
Query: 518 NQRRPWCYVQVGLKQLVQECMVPNCSGGE 604
PWCY + C + CS E
Sbjct: 3502 PVAAPWCYT-TDPSVRWEYCNLTRCSDAE 3529
Score = 54.3 bits (129), Expect = 2e-07
Identities = 32/89 (35%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C+ G+G SYRG +T GR C W+S T + ++ + GL NYCRNPD
Sbjct: 26 QDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTP--HQHNRTTENYPNAGL-IMNYCRNPDA 82
Query: 521 QRRPWCYVQ-VGLKQLVQECMVPNCSGGE 604
P+CY + G++ + C + CS E
Sbjct: 83 VAAPYCYTRDPGVRW--EYCNLTQCSDAE 109
>ref|XP_946885.1| PREDICTED: similar to Apolipoprotein(a) precursor (Apo(a)) (Lp(a))
[Homo sapiens]
Length = 440
Score = 89.4 bits (220), Expect = 4e-18
Identities = 68/222 (30%), Positives = 87/222 (39%), Gaps = 17/222 (7%)
Frame = +2
Query: 272 FSNIQRCSC--------PKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCLPWNS 427
+ N+ RCS P Q + Q C GNG YRGK T G PC W +
Sbjct: 26 YCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQEWAA 85
Query: 428 ATVLLNTYHAHRPDALQLGLGK-----HNYCRNPDNQ-RRPWCYVQVGLKQLVQECMVPN 589
HR G K NYCRNPD PWCY + ++L C +P
Sbjct: 86 Q-------EPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYT-MNPRKLFDYCDIPL 137
Query: 590 CSGGESHRPAYDGKNPFSTPEKVEFQCGQKALRPRF---KIVGGKSTTIENQPWFAAIYR 760
C+ F CG+ + P+ IVGG + PW ++
Sbjct: 138 CASSS-------------------FDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSL-- 176
Query: 761 RHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLG 886
R R G + CGG+LISP WV++A HC Y V LG
Sbjct: 177 RTRFGK--HFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILG 216
>ref|XP_931416.1| PREDICTED: similar to Apolipoprotein(a) precursor (Apo(a)) (Lp(a))
[Homo sapiens]
Length = 440
Score = 89.4 bits (220), Expect = 4e-18
Identities = 68/222 (30%), Positives = 87/222 (39%), Gaps = 17/222 (7%)
Frame = +2
Query: 272 FSNIQRCSC--------PKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCLPWNS 427
+ N+ RCS P Q + Q C GNG YRGK T G PC W +
Sbjct: 26 YCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQEWAA 85
Query: 428 ATVLLNTYHAHRPDALQLGLGK-----HNYCRNPDNQ-RRPWCYVQVGLKQLVQECMVPN 589
HR G K NYCRNPD PWCY + ++L C +P
Sbjct: 86 Q-------EPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYT-MNPRKLFDYCDIPL 137
Query: 590 CSGGESHRPAYDGKNPFSTPEKVEFQCGQKALRPRF---KIVGGKSTTIENQPWFAAIYR 760
C+ F CG+ + P+ IVGG + PW ++
Sbjct: 138 CASSS-------------------FDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSL-- 176
Query: 761 RHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLG 886
R R G + CGG+LISP WV++A HC Y V LG
Sbjct: 177 RTRFGK--HFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILG 216
Database: RefSeqHP
Posted date: Aug 2, 2006 12:57 AM
Number of letters in database: 17,774,539
Number of sequences in database: 39,411
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,026,609
Number of Sequences: 39411
Number of extensions: 1366140
Number of successful extensions: 6246
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 4591
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6039
length of database: 17,774,539
effective HSP length: 102
effective length of database: 13,754,617
effective search space used: 3067279591
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqMP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-005822
(977 letters)
Database: RefSeqMP
45,328 sequences; 21,768,885 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_032899.1| plasminogen activator, urokinase [Mus musculus] 348 4e-96
Alignment gi|NP_062320.1| hepatocyte growth factor activator [Mus musculus] 144 1e-34
Alignment gi|NP_666213.1| hyaluronic acid binding protein 2 [Mus musculus] 135 5e-32
Alignment gi|NP_067464.1| coagulation factor XII (Hageman factor) [Mus mu... 135 5e-32
Alignment gi|NP_032898.1| plasminogen activator, tissue [Mus musculus] 135 6e-32
Alignment gi|NP_032903.2| plasminogen [Mus musculus] 96 7e-20
Alignment gi|NP_034557.2| hepatocyte growth factor [Mus musculus] 79 9e-15
Alignment gi|NP_032269.2| macrophage stimulating 1 (hepatocyte growth fac... 75 1e-13
Alignment gi|NP_115772.2| kringle-containing transmembrane protein 1 [Mus... 68 2e-11
Alignment gi|NP_082692.1| kringle-containing transmembrane protein 2 [Mus... 67 3e-11
>ref|NP_032899.1| plasminogen activator, urokinase [Mus musculus]
Length = 433
Score = 348 bits (894), Expect = 4e-96
Identities = 165/253 (65%), Positives = 193/253 (76%), Gaps = 2/253 (0%)
Frame = +2
Query: 224 SNCGCLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGG 403
SNCGC NGG CVSYKYFS I+RCSCP+KFQGEHCEID S+TC+ GNG SYRGKANT+T G
Sbjct: 30 SNCGCQNGGVCVSYKYFSRIRRCSCPRKFQGEHCEIDASKTCYHGNGDSYRGKANTDTKG 89
Query: 404 RPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMV 583
RPCL WN+ VL Y+AHRPDA+ LGLGKHNYCRNPDNQ+RPWCYVQ+GL+Q VQECMV
Sbjct: 90 RPCLAWNAPAVLQKPYNAHRPDAISLGLGKHNYCRNPDNQKRPWCYVQIGLRQFVQECMV 149
Query: 584 PNCSGGESHRPAYDGKNPFSTPEKVEFQCGQKALRPRFKIVGGKSTTIENQPWFAAIYRR 763
+CS K P S+ ++ FQCGQKALRPRFKIVGG+ T +ENQPWFAAIY++
Sbjct: 150 HDCS---------LSKKPSSSVDQQGFQCGQKALRPRFKIVGGEFTEVENQPWFAAIYQK 200
Query: 764 HRGGS-VTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLGRQPFTPALMGR*N*G-GK 937
++GGS ++ CGGSLISPCWV SA HCFI KE+Y+VYLG+ + G +
Sbjct: 201 NKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVVYLGQSKESSYNPGEMKFEVEQ 260
Query: 938 LILHEDYSADSLA 976
LILHE Y DSLA
Sbjct: 261 LILHEYYREDSLA 273
>ref|NP_062320.1| hepatocyte growth factor activator [Mus musculus]
Length = 653
Score = 144 bits (363), Expect = 1e-34
Identities = 90/229 (39%), Positives = 110/229 (48%), Gaps = 8/229 (3%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
CLNGG C + C+CP + G C I ++ CF GNG YRG A+T G CL
Sbjct: 247 CLNGGTC-HLIVGTGTSVCTCPLGYAGRFCNIVPTEHCFLGNGTEYRGVASTAASGLSCL 305
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
WNS + + A+ LGLG H YCRNPD RPWCYV + C + C
Sbjct: 306 AWNSDLLYQELHVDSVAAAVLLGLGPHAYCRNPDKDERPWCYVVKDNALSWEYCRLTACE 365
Query: 596 G---GESHRPAYDGKNPFSTPEKVEFQCGQK-----ALRPRFKIVGGKSTTIENQPWFAA 751
S P P S P V CG++ LRPR I+GG S+ + PW AA
Sbjct: 366 SLARVHSQTPEILAALPESAP-AVRPTCGKRHKKRTFLRPR--IIGGSSSLPGSHPWLAA 422
Query: 752 IYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLGRQPF 898
IY G S C GSL+ CWVVSA HCF N ++ V LG+ F
Sbjct: 423 IY---IGNS---FCAGSLVHTCWVVSAAHCFANSPPRDSITVVLGQHFF 465
>ref|NP_666213.1| hyaluronic acid binding protein 2 [Mus musculus]
Length = 517
Score = 135 bits (341), Expect = 5e-32
Identities = 79/226 (34%), Positives = 115/226 (50%), Gaps = 7/226 (3%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
C NGG C ++ S C+CP +++G+ CEI C+ G+G+SYRGK + PCL
Sbjct: 116 CQNGGVCSRHRRRSRFT-CACPDQYKGKFCEIGPDD-CYVGDGYSYRGKVSKTVNQNPCL 173
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQE-CMVPNC 592
WNS +L TY+ DA G+ +HN+CRNPD +PWC+V+V +++ E C V C
Sbjct: 174 YWNSHLLLQETYNMFMEDAETHGIAEHNFCRNPDGDHKPWCFVKVNSEKVKWEYCDVTVC 233
Query: 593 SGGESHRPAYDGKNPFSTPEKVEFQCGQKALRPRF--KIVGGKSTTIENQPWFAAIYRR- 763
++ P P E CG+ + +I GG +T PW ++
Sbjct: 234 PVPDTPNPVESLLEPVMELPGFE-SCGKTEVAEHAVKRIYGGFKSTAGKHPWQVSLQTSL 292
Query: 764 --HRGGSVTYVCGGSLISPCWVVSATHCF-INYQHKEDYIVYLGRQ 892
+ CGG+LI PCWV++A HC IN +H + V LG Q
Sbjct: 293 PLTTSMPQGHFCGGALIHPCWVLTAAHCTDINTKHLK---VVLGDQ 335
>ref|NP_067464.1| coagulation factor XII (Hageman factor) [Mus musculus]
Length = 597
Score = 135 bits (341), Expect = 5e-32
Identities = 86/262 (32%), Positives = 116/262 (44%), Gaps = 26/262 (9%)
Frame = +2
Query: 182 DSKGSHELHQESGASNCG---CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCF 352
+ KGS + + C CLNGG C+ + + C CP + G C++D TC+
Sbjct: 162 ECKGSEAHCKPVASQACSINPCLNGGSCLLVE---DHPLCRCPTGYTGYFCDLDLWATCY 218
Query: 353 EGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRP 532
EG G SYRG+A T G PC W TV + AL GLG H +CRNPDN RP
Sbjct: 219 EGRGLSYRGQAGTTQSGAPCQRW---TVEATYRNMTEKQALSWGLGHHAFCRNPDNDTRP 275
Query: 533 WCYVQVGLKQLVQECMVPNC--------------------SGGESHRPAYDGKNPFSTPE 652
WC+V G + C + C + SH P + S +
Sbjct: 276 WCFVWSGDRLSWDYCGLEQCQTPTFAPLVVPESQEESPSQAPSLSHAPNDSTDHQTSLSK 335
Query: 653 KVEFQCGQ---KALRPRFKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWV 823
CGQ K L ++VGG + P+ AA+Y + C GSLI+PCWV
Sbjct: 336 TNTMGCGQRFRKGLSSFMRVVGGLVALPGSHPYIAALYWGNN------FCAGSLIAPCWV 389
Query: 824 VSATHCFINYQHKEDYIVYLGR 889
++A HC N E+ V LG+
Sbjct: 390 LTAAHCLQNRPAPEELTVVLGQ 411
>ref|NP_032898.1| plasminogen activator, tissue [Mus musculus]
Length = 559
Score = 135 bits (340), Expect = 6e-32
Identities = 63/132 (47%), Positives = 78/132 (59%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 415
C NGG C YFS+ C CP F G+ C+IDT TCFE G +YRG +T G C+
Sbjct: 88 CFNGGTCQQALYFSDFV-CQCPDGFVGKRCDIDTRATCFEEQGITYRGTWSTAESGAECI 146
Query: 416 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
WNS+ + L Y+A RP+A++LGLG HNYCRNPD +PWCYV K + C P C
Sbjct: 147 NWNSSVLSLKPYNARRPNAIKLGLGNHNYCRNPDRDLKPWCYVFKAGKYTTEFCSTPACP 206
Query: 596 GGESHRPAYDGK 631
G+S Y GK
Sbjct: 207 KGKS-EDCYVGK 217
Score = 133 bits (334), Expect = 3e-31
Identities = 75/202 (37%), Positives = 99/202 (49%), Gaps = 2/202 (0%)
Frame = +2
Query: 290 CSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPD 469
CS P C S+ C+ G G +YRG + T CLPWNS ++ +Y A R +
Sbjct: 200 CSTPA------CPKGKSEDCYVGKGVTYRGTHSLTTSQASCLPWNSIVLMGKSYTAWRTN 253
Query: 470 ALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTP 649
+ LGL +HNYCRNPD RPWC+V K + C + CS
Sbjct: 254 SQALGLARHNYCRNPDGDARPWCHVMKDRKLTWEYCDMSPCS------------------ 295
Query: 650 EKVEFQCG-QKALRPRFKIVGGKSTTIENQPWFAAIY-RRHRGGSVTYVCGGSLISPCWV 823
CG ++ RP+F+I GG T I + PW AAI+ + R ++CGG LIS CWV
Sbjct: 296 -----TCGLRQYKRPQFRIKGGLYTDITSHPWQAAIFVKNKRSPGERFLCGGVLISSCWV 350
Query: 824 VSATHCFINYQHKEDYIVYLGR 889
+SA HCF+ V LGR
Sbjct: 351 LSAAHCFLERFPPNHLKVVLGR 372
>ref|NP_032903.2| plasminogen [Mus musculus]
Length = 812
Score = 95.5 bits (236), Expect = 7e-20
Identities = 68/229 (29%), Positives = 97/229 (42%), Gaps = 12/229 (5%)
Frame = +2
Query: 236 CLNGGKCVSYKYFSNIQRCS--------CPKKFQGEHCEIDTSQTCFEGNGHSYRGKANT 391
C V ++Y N++RCS P Q D+ C GNG YRGK
Sbjct: 437 CYTTDPSVRWEY-CNLKRCSETGGSVVELPTVSQEPSGPSDSETDCMYGNGKDYRGKTAV 495
Query: 392 NTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQ-RRPWCYVQVGLKQLV 568
G PC W + ++ + + + GL K NYCRNPD PWCY ++L
Sbjct: 496 TAAGTPCQGWAAQEPHRHSIFTPQTNP-RAGLEK-NYCRNPDGDVNGPWCYT-TNPRKLY 552
Query: 569 QECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQKALRPRF---KIVGGKSTTIENQP 739
C +P C+ S F+CG+ + P+ ++VGG + P
Sbjct: 553 DYCDIPLCASASS------------------FECGKPQVEPKKCPGRVVGGCVANPHSWP 594
Query: 740 WFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYIVYLG 886
W ++ R G + CGG+LI+P WV++A HC E Y V LG
Sbjct: 595 WQISLRTRFTG---QHFCGGTLIAPEWVLTAAHCLEKSSRPEFYKVILG 640
Score = 62.8 bits (151), Expect = 5e-10
Identities = 49/164 (29%), Positives = 64/164 (39%), Gaps = 14/164 (8%)
Frame = +2
Query: 317 EHCEIDTSQT----------CFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRP 466
E+C+I T C +G G +YRG + G+ C W+ T H P
Sbjct: 255 EYCDIPRCTTPPPPPSPTYQCLKGRGENYRGTVSVTVSGKTCQRWSEQTP---HRHNRTP 311
Query: 467 DALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQE-CMVPNCSGGESHRPAYDGKNPFS 643
+ + NYCRNPD + PWCY QL E C +P+C S + D P
Sbjct: 312 ENFPCKNLEENYCRNPDGETAPWCYTTD--SQLRWEYCEIPSCESSASPDQS-DSSVPPE 368
Query: 644 TPEKVEFQCGQKALRPRFKIVGGKSTTIEN---QPWFAAIYRRH 766
V +C Q + G STTI Q W A RH
Sbjct: 369 EQTPVVQECYQSDGQ---SYRGTSSTTITGKKCQSWAAMFPHRH 409
Score = 57.0 bits (136), Expect = 3e-08
Identities = 24/67 (35%), Positives = 35/67 (52%)
Frame = +2
Query: 341 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
Q C++ +G SYRG ++T G+ C W + H+ P+ + NYCRNPD
Sbjct: 375 QECYQSDGQSYRGTSSTTITGKKCQSW---AAMFPHRHSKTPENFPDAGLEMNYCRNPDG 431
Query: 521 QRRPWCY 541
+ PWCY
Sbjct: 432 DKGPWCY 438
Score = 56.2 bits (134), Expect = 5e-08
Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Frame = +2
Query: 317 EHCEI-DTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGK 493
++C I + + C +G Y GK + G C W+S + + Y + + L K
Sbjct: 174 DYCNIPECEEECMYCSGEKYEGKISKTMSGLDCQAWDSQSPHAHGYIPAKFPSKNL---K 230
Query: 494 HNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 595
NYCRNPD + RPWC+ K+ + C +P C+
Sbjct: 231 MNYCRNPDGEPRPWCFTTDPTKRW-EYCDIPRCT 263
>ref|NP_034557.2| hepatocyte growth factor [Mus musculus]
Length = 728
Score = 78.6 bits (192), Expect = 9e-15
Identities = 53/190 (27%), Positives = 82/190 (43%), Gaps = 2/190 (1%)
Frame = +2
Query: 323 CEIDTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNY 502
C++ + Q C+ GNG +Y G + G C W+ L+ + PDA +L NY
Sbjct: 384 CDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWDKNMEDLHRHIFWEPDASKL---NKNY 440
Query: 503 CRNPDNQRR-PWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQK 679
CRNPD+ PWCY L C + C G + T ++
Sbjct: 441 CRNPDDDAHGPWCYTGNPLIPW-DYCPISRCEGDTT-----------PTIVNLDHPVISC 488
Query: 680 ALRPRFKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCF-INYQ 856
A + ++V G T W ++ R++ ++CGGSLI WV++A CF +
Sbjct: 489 AKTKQLRVVNGIPTQ-TTVGWMVSLKYRNK-----HICGGSLIKESWVITARQCFPARNK 542
Query: 857 HKEDYIVYLG 886
+DY +LG
Sbjct: 543 DLKDYEAWLG 552
Score = 58.9 bits (141), Expect = 8e-09
Identities = 35/101 (34%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Frame = +2
Query: 347 CFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQR 526
C +G G YRG +NT G PC W+S H P+ + + NYCRNPD
Sbjct: 306 CIQGQGEGYRGTSNTIWNGIPCQRWDSQ---YPHKHDITPENFKCKDLRENYCRNPDGAE 362
Query: 527 RPWCY-----VQVGLKQLVQECMVPNCSGGESHRPAYDGKN 634
PWC+ ++VG + +C V SG + +R +GKN
Sbjct: 363 SPWCFTTDPNIRVGYCSQIPKCDV--SSGQDCYRG--NGKN 399
Score = 54.7 bits (130), Expect = 1e-07
Identities = 33/106 (31%), Positives = 48/106 (45%), Gaps = 8/106 (7%)
Frame = +2
Query: 332 DTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRN 511
D + C G G SY+G + G C PWNS ++ H+ P + + + NYCRN
Sbjct: 124 DYIRNCIIGKGGSYKGTVSITKSGIKCQPWNS---MIPHEHSFLPSSYRGKDLQENYCRN 180
Query: 512 PDNQR-RPWCYVQVGLKQLVQECMVPNCS-------GGESHRPAYD 625
P + PWC+ + + C +P CS GES+R D
Sbjct: 181 PRGEEGGPWCFTS-NPEVRYEVCDIPQCSEVECMTCNGESYRGPMD 225
Score = 54.3 bits (129), Expect = 2e-07
Identities = 36/121 (29%), Positives = 51/121 (42%), Gaps = 4/121 (3%)
Frame = +2
Query: 317 EHCEID--TSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHR--PDALQLG 484
E C+I + C NG SYRG + G+ C W+ T H H+ P+
Sbjct: 200 EVCDIPQCSEVECMTCNGESYRGPMDHTESGKTCQRWDQQTP-----HRHKFLPERYPDK 254
Query: 485 LGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEF 664
NYCRNPD + RPWCY + + C + C +H + P T E ++
Sbjct: 255 GFDDNYCRNPDGKPRPWCYT-LDPDTTWEYCAIKTC----AHSAVNETDVPMETTECIQG 309
Query: 665 Q 667
Q
Sbjct: 310 Q 310
>ref|NP_032269.2| macrophage stimulating 1 (hepatocyte growth factor-like) [Mus
musculus]
Length = 716
Score = 74.7 bits (182), Expect = 1e-13
Identities = 57/189 (30%), Positives = 89/189 (47%), Gaps = 9/189 (4%)
Frame = +2
Query: 347 CFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRP-----DALQLGLGKHNYCRN 511
C+ G+G YRG + G C W+S T H+P A Q GL + N+CRN
Sbjct: 379 CYHGSGEQYRGSVSKTRKGVQCQHWSSET-------PHKPQFTPTSAPQAGL-EANFCRN 430
Query: 512 PD-NQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQ-CGQKAL 685
PD + PWCY + L C + C + + P++V F+ CG++
Sbjct: 431 PDGDSHGPWCYT-LDPDILFDYCALQRCDDDQP-------PSILDPPDQVVFEKCGKRVD 482
Query: 686 RP-RFKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFIN-YQH 859
+ + ++VGG N PW ++ R+R G + CGGSL+ WV++A C + ++
Sbjct: 483 KSNKLRVVGGHP---GNSPWTVSL--RNRQGQ--HFCGGSLVKEQWVLTARQCIWSCHEP 535
Query: 860 KEDYIVYLG 886
Y V+LG
Sbjct: 536 LTGYEVWLG 544
Score = 59.7 bits (143), Expect = 4e-09
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Frame = +2
Query: 347 CFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHR--PDALQLGLGKHNYCRNPDN 520
CF G G YRG NT + G PC W++ + H HR P+ + N+CRNPD
Sbjct: 292 CFRGKGEDYRGTTNTTSAGVPCQRWDAQSP-----HQHRFVPEKYACKDLRENFCRNPDG 346
Query: 521 QRRPWCYVQVGLKQLVQECMVPNCS 595
PWC+ ++ +P C+
Sbjct: 347 SEAPWCFTSRPGLRMAFCHQIPRCT 371
Score = 57.4 bits (137), Expect = 2e-08
Identities = 45/163 (27%), Positives = 62/163 (38%), Gaps = 4/163 (2%)
Frame = +2
Query: 317 EHCEIDTSQ--TCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAH--RPDALQLG 484
+ C I T + C NG YRG+ + GR C W+ L H+H +P+
Sbjct: 179 QSCGIKTCREAVCVLCNGEDYRGEVDVTESGRECQRWD-----LQHPHSHPFQPEKFLDK 233
Query: 485 LGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEF 664
K NYCRNPD RPWCY + + C +P+C G + P G +
Sbjct: 234 DLKDNYCRNPDGSERPWCYTTDPNVER-EFCDLPSC--GPNLPPTVKGSKSQRRNKGKAL 290
Query: 665 QCGQKALRPRFKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVC 793
C + S + Q W A +HR Y C
Sbjct: 291 NCFRGKGEDYRGTTNTTSAGVPCQRWDAQSPHQHRFVPEKYAC 333
Score = 52.4 bits (124), Expect = 7e-07
Identities = 36/106 (33%), Positives = 45/106 (42%), Gaps = 8/106 (7%)
Frame = +2
Query: 332 DTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRN 511
D +TC NG SYRG GG PC W+ H + P + GL + N+CRN
Sbjct: 105 DYVRTCIMDNGVSYRGTVARTAGGLPCQAWSRR---FPNDHKYTPTP-KNGL-EENFCRN 159
Query: 512 PD-NQRRPWCYVQVGLKQLVQECMVPNC-------SGGESHRPAYD 625
PD + R PWCY Q C + C GE +R D
Sbjct: 160 PDGDPRGPWCYT-TNRSVRFQSCGIKTCREAVCVLCNGEDYRGEVD 204
>ref|NP_115772.2| kringle-containing transmembrane protein 1 [Mus musculus]
Length = 473
Score = 67.8 bits (164), Expect = 2e-11
Identities = 56/173 (32%), Positives = 71/173 (41%), Gaps = 16/173 (9%)
Frame = +2
Query: 347 CFEGNGHSYRGKANTNT--GGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 520
CF NG YRG + GG+PCL WN + Y+ + + GLG+HNYCRNPD
Sbjct: 32 CFTANGADYRGTQSWTALQGGKPCLFWNET--FQHPYNTLKYPNGEGGLGEHNYCRNPDG 89
Query: 521 QRRPWCYVQVGLKQLV-QECMVPNCSGGESHRPAYDGKNP------FSTPEKVEFQ-CGQ 676
PWCYV + + C +P C + D NP T K+ Q C
Sbjct: 90 DVSPWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTCIS 149
Query: 677 KALRPRFKIVG---GKSTTIENQPWFAAIYRRHRGGSVT---YVCGGSLISPC 817
RFK G G + N P Y +H + T VC G PC
Sbjct: 150 FCRSQRFKFAGMESGYACFCGNNP----DYWKHGEAASTECNSVCFGDHTQPC 198
>ref|NP_082692.1| kringle-containing transmembrane protein 2 [Mus musculus]
Length = 461
Score = 67.0 bits (162), Expect = 3e-11
Identities = 37/98 (37%), Positives = 49/98 (50%), Gaps = 4/98 (4%)
Frame = +2
Query: 347 CFEGNGHSYRGKAN---TNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPD 517
CF+ NG YRG N GRPCL W+ ++Y + + GLG HN+CRNPD
Sbjct: 35 CFQVNGADYRGHQNYTGPRGAGRPCLFWDQTQQ--HSYSSASDPQGRWGLGAHNFCRNPD 92
Query: 518 NQRRPWCYVQVGLKQLV-QECMVPNCSGGESHRPAYDG 628
+PWCYV + + + C +P C H P Y G
Sbjct: 93 GDVQPWCYVAETEEGIYWRYCDIPTC-----HMPGYLG 125
Database: RefSeqMP
Posted date: Aug 2, 2006 12:58 AM
Number of letters in database: 21,768,885
Number of sequences in database: 45,328
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,263,905
Number of Sequences: 45328
Number of extensions: 1558387
Number of successful extensions: 6928
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 5318
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6750
length of database: 21,768,885
effective HSP length: 104
effective length of database: 17,054,773
effective search space used: 3769104833
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)