BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-007176
(1854 letters)
Database: RefSeqSP
1040 sequences; 434,620 total letters
Searching...done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_999219.1| T-plasminogen activator [Sus scrofa] 1083 0.0
Alignment gi|NP_999407.1| factor XII [Sus scrofa] 231 4e-62
Alignment gi|NP_999110.1| plasminogen activator [Sus scrofa] 216 1e-57
Alignment gi|NP_999198.1| preproacrosin [Sus scrofa] 97 1e-21
Alignment gi|NP_999274.1| pancreatic elastase II [Sus scrofa] 93 2e-20
Alignment gi|NP_999356.1| tryptase [Sus scrofa] 88 8e-19
Alignment gi|NP_999239.1| kallikrein [Sus scrofa] 85 5e-18
Alignment gi|NP_001001259.1| enteropeptidase, light chain (L chain) [Sus ... 84 1e-17
Alignment gi|NP_001001911.1| kallikrein 1, renal/pancreas/salivary [Sus s... 84 1e-17
Alignment gi|NP_999083.1| protein C [Sus scrofa] 83 2e-17
>ref|NP_999219.1| T-plasminogen activator [Sus scrofa]
Length = 562
Score = 1083 bits (2801), Expect = 0.0
Identities = 498/515 (96%), Positives = 501/515 (97%)
Frame = +2
Query: 308 MYALKRELWCVLLLCGAICTSPSQETHXXXXXXXXXXXVTCRDEKTQMIYQQHQSWLRPL 487
MYALKRELWCVLLLCGAICTSPSQETH VTCRDEKTQMIYQQHQSWLRPL
Sbjct: 1 MYALKRELWCVLLLCGAICTSPSQETHRRLRRGVRSYRVTCRDEKTQMIYQQHQSWLRPL 60
Query: 488 LRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCE 667
LRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQA+YFSDFVCQCPVGFIGRQCE
Sbjct: 61 LRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQAIYFSDFVCQCPVGFIGRQCE 120
Query: 668 IDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCR 847
IDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCR
Sbjct: 121 IDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCR 180
Query: 848 NPDKDSKPWCYIFKAEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWN 1027
NPDKDSKPWCYIFKAEKY PDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWN
Sbjct: 181 NPDKDSKPWCYIFKAEKYSPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWN 240
Query: 1028 SLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVTCG 1207
SLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVTCG
Sbjct: 241 SLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVTCG 300
Query: 1208 LRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQ 1387
LRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQ
Sbjct: 301 LRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQ 360
Query: 1388 ERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDNDIALLQLKSDSLTCA 1567
ERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDNDIALLQLKSDSLTCA
Sbjct: 361 ERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDNDIALLQLKSDSLTCA 420
Query: 1568 QESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSSCCTSKH 1747
QESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSS CTSKH
Sbjct: 421 QESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSSRCTSKH 480
Query: 1748 LFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
LFNKTIT +MLCAGDTRSGGD+ANLHDACQGDSGG
Sbjct: 481 LFNKTITNNMLCAGDTRSGGDNANLHDACQGDSGG 515
>ref|NP_999407.1| factor XII [Sus scrofa]
Length = 616
Score = 231 bits (589), Expect = 4e-62
Identities = 157/482 (32%), Positives = 228/482 (47%), Gaps = 7/482 (1%)
Frame = +2
Query: 428 CRDEKTQMIYQQHQSWLRPLLRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQA 607
C + + +Q+++ W R G V C C + QC V + CS C NGG+CLQ
Sbjct: 135 CFEPQFLQFFQENEIWHRFEPAG--VSKCQCKGPKAQCKPVASQVCSTNPCLNGGSCLQT 192
Query: 608 VYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMP 787
+C+CP G+ GR C++D + CY D+G++YRG TT SGA C W + +
Sbjct: 193 E--GHRLCRCPTGYAGRLCDVDLKERCYSDRGLSYRGMAQTTLSGAPCQPWASE---ATY 247
Query: 788 YNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPACTKEKEECYTGKG 967
+N A+ GLG+H +CRNPD D++PWC++++ ++ +C C E
Sbjct: 248 WNMTAEQALNWGLGDHAFCRNPDNDTRPWCFVWRGDQLSWQYCRLARCQAPIGE------ 301
Query: 968 LDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHV 1147
LT + + +S +L + + +Q L T WC
Sbjct: 302 ----APPILTPTQSPSEHQDSPLLSREPQPTTQTPSQNL--------------TSAWCAP 343
Query: 1148 LKDHKLTWEYCDLPQC--VTCG--LRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSP 1315
+ LP V CG LR+ RI GGL A +HP+ AA++
Sbjct: 344 PEQRG------PLPSAGLVGCGQRLRKRLSSLNRIVGGLVALPGAHPYIAALYW------ 391
Query: 1316 GERFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHK 1495
G+ F C G LI+ CWVL+AAHC Q R P + VVLG+ E+ Q V Y +H+
Sbjct: 392 GQNF-CAGSLIAPCWVLTAAHCLQNRPAPEELTVVLGQDRHNQSCEQCQTLAVRSYRLHE 450
Query: 1496 EFDDDTYDNDIALLQLKSDS-LTCAQESDAVRTVCLPE--ANLQLPDWTECELSGYGKHE 1666
+ TY +D+AL++LK + CA S V+ VCLP A+ P+ CE++G+G
Sbjct: 451 SYSPKTYQHDLALVRLKETADGCCAHPSPFVQPVCLPRSVASSAEPEGALCEVAGWGHQF 510
Query: 1667 ASSPFYSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDS 1846
+ YS L+EA V L C++ + T MLCAG G DACQGDS
Sbjct: 511 EGAEEYSSFLQEAQVPLISPERCSAADVHGAAFTPGMLCAGFLEGG------TDACQGDS 564
Query: 1847 GG 1852
GG
Sbjct: 565 GG 566
>ref|NP_999110.1| plasminogen activator [Sus scrofa]
Length = 442
Score = 216 bits (551), Expect = 1e-57
Identities = 122/328 (37%), Positives = 165/328 (50%), Gaps = 25/328 (7%)
Frame = +2
Query: 944 EECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDG 1123
+ C+ G G YRG + G CLPWNS ++ Y A +A LGLGKHNYCRNPD
Sbjct: 70 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN 129
Query: 1124 DTQPWCHVLKDHKLTWEYCDLPQC-----------------------VTCGLRQYKEPQF 1234
+PWC+V K + C +P C CG + + P+F
Sbjct: 130 QRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQKALR-PRF 188
Query: 1235 RIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQERFPPHHVR 1414
+I GG I + PW AAI+ + R ++CGG LIS CWV+SA HCF
Sbjct: 189 KIVGGKSTTIENQPWFAAIY-RRHRGGSVTYVCGGSLISPCWVVSATHCFINYQHKEDYI 247
Query: 1415 VVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDT--YDNDIALLQLKSDSLTCAQESDAVR 1588
V LGR E FEVEK I+H+++ D+ + NDIALL++++D CAQ S +++
Sbjct: 248 VYLGRQTLHSSTHGEMKFEVEKLILHEDYSADSLAHHNDIALLKIRTDKGQCAQPSRSIQ 307
Query: 1589 TVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSSCCTSKHLFNKTIT 1768
T+CLP N CE+ G+GK + S Y E+LK V+L C H + +T
Sbjct: 308 TICLPPVNGDAHFGASCEIVGFGKEDPSDYLYPEQLKMTVVKLVSHRECQQPHYYGSEVT 367
Query: 1769 KHMLCAGDTRSGGDDANLHDACQGDSGG 1852
MLCA D + D+CQGDSGG
Sbjct: 368 TKMLCAADPQW------KTDSCQGDSGG 389
Score = 127 bits (319), Expect = 9e-31
Identities = 57/132 (43%), Positives = 74/132 (56%), Gaps = 3/132 (2%)
Frame = +2
Query: 578 CFNGGTCLQAVYFSDFV-CQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESGAECV 754
C NGG C+ YFS+ C CP F G CEID TC+E G +YRG +T G C+
Sbjct: 35 CLNGGKCVSYKYFSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCL 94
Query: 755 NWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPACT 934
WN++ + Y+ RPDA++LGLG HNYCRNPD +PWCY+ K + C P C+
Sbjct: 95 PWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 154
Query: 935 --KEKEECYTGK 964
+ Y GK
Sbjct: 155 GGESHRPAYDGK 166
>ref|NP_999198.1| preproacrosin [Sus scrofa]
Length = 400
Score = 97.4 bits (241), Expect = 1e-21
Identities = 74/234 (31%), Positives = 112/234 (47%), Gaps = 9/234 (3%)
Frame = +2
Query: 1178 CDLPQCVTCGLR--QYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILIS 1351
CD P CGLR Q E R+ GG+ A+ + PW ++ + + CGGIL++
Sbjct: 21 CDGP----CGLRFRQKLESGMRVVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLN 76
Query: 1352 SCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEE------QAFEVEKYIVHKEFDDDT 1513
S WVL+AAHCF+ + R++ G +V G + Q VE+ I+H+++
Sbjct: 77 SHWVLTAAHCFKNKKKVTDWRLIFGAN-EVVWGSNKPVKPPLQERFVEEIIIHEKYVSGL 135
Query: 1514 YDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTE-CELSGYGKHEASSPFYSE 1690
NDIAL+++ + + C + CLP+ P + C ++G+G + P S
Sbjct: 136 EINDIALIKI-TPPVPC---GPFIGPGCLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSP 191
Query: 1691 RLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
L+EA V L C S +N +T +CAG R D CQGDSGG
Sbjct: 192 TLQEARVALIDLELCNSTQWYNGRVTSTNVCAGYPR------GKIDTCQGDSGG 239
>ref|NP_999274.1| pancreatic elastase II [Sus scrofa]
Length = 269
Score = 92.8 bits (229), Expect = 2e-20
Identities = 72/223 (32%), Positives = 111/223 (49%), Gaps = 4/223 (1%)
Frame = +2
Query: 1196 VTCGLRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGE-RFLCGGILISSCWVLSA 1372
++CGL R+ GG A S PWQ ++ S G+ R CGG L+ WVL+A
Sbjct: 15 LSCGLPANLPQLPRVVGGEDARPNSWPWQVSL---QYDSSGQWRHTCGGTLVDQSWVLTA 71
Query: 1373 AHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDD--TYDNDIALLQLK 1546
AHC RVVLGR A +V K +VH++++ + + NDIALL+L
Sbjct: 72 AHCISS---SRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLA 128
Query: 1547 SD-SLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLYP 1723
S SLT D ++ CLP A LP+ C ++G+G+ + + + L++ + +
Sbjct: 129 SPVSLT-----DKIQLGCLPAAGTILPNNYVCYVTGWGRLQTNGA-SPDILQQGQLLVVD 182
Query: 1724 SSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
+ C+ + T+ +M+CA GGD + +C GDSGG
Sbjct: 183 YATCSKPGWWGSTVKTNMICA-----GGD--GIISSCNGDSGG 218
>ref|NP_999356.1| tryptase [Sus scrofa]
Length = 275
Score = 87.8 bits (216), Expect = 8e-19
Identities = 71/214 (33%), Positives = 102/214 (47%), Gaps = 9/214 (4%)
Frame = +2
Query: 1238 IKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCF-QERFPPHHVR 1414
I GG A PWQ ++ ++ + CGG LI WVL+AAHCF E+ P ++R
Sbjct: 31 IVGGKEAPGHKWPWQVSLRCLDQYW---KHFCGGSLIHPQWVLTAAHCFGPEKADPLYIR 87
Query: 1415 VVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDNDIALLQLKSDSLTCAQESDAVRTV 1594
V LG + +++ V + IVH + D+ DIALL+L+ S V+ V
Sbjct: 88 VQLGEQHLYY---QDRLLLVSRIIVHPNYYDEVNGADIALLELEDP----VNLSSHVQPV 140
Query: 1595 CLPEANLQLPDWTECELSGYGKHEASSPFYSE-RLKEAHVRLYPSSCCTSK-HLFNKT-- 1762
LP A+ P T C ++G+G + P LK+ V + +S C + HL T
Sbjct: 141 TLPPASETFPKGTRCWVTGWGDVHSGWPLPPPYPLKQVRVPIVENSECDMQYHLGLSTGD 200
Query: 1763 ----ITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
+ MLCAG + HD+CQGDSGG
Sbjct: 201 NIPIVRDDMLCAG--------SEGHDSCQGDSGG 226
>ref|NP_999239.1| kallikrein [Sus scrofa]
Length = 643
Score = 85.1 bits (209), Expect = 5e-18
Identities = 63/206 (30%), Positives = 100/206 (48%)
Frame = +2
Query: 1235 RIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQERFPPHHVR 1414
RI GG + + PWQ ++ K R + LCGG +I WVL+AAHCF P R
Sbjct: 398 RIVGGTDSFLGEWPWQVSLQAKLR---AQNHLCGGSIIGHQWVLTAAHCFDGLSLPDIWR 454
Query: 1415 VVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDNDIALLQLKSDSLTCAQESDAVRTV 1594
+ G +E +V++ I+H+ + +DIALL+L+ T +D + +
Sbjct: 455 IYGGILNISEITKETPFSQVKEIIIHQNYKILESGHDIALLKLE----TPLNYTDFQKPI 510
Query: 1595 CLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSSCCTSKHLFNKTITKH 1774
CLP + +T C ++G+G E L++ ++ L + C + +K I+K
Sbjct: 511 CLPSRDDTNVVYTNCWVTGWGFTEEKGEI-QNILQKVNIPLVSNEECQKSYRDHK-ISKQ 568
Query: 1775 MLCAGDTRSGGDDANLHDACQGDSGG 1852
M+CAG G DAC+G+SGG
Sbjct: 569 MICAGYKEGG------KDACKGESGG 588
>ref|NP_001001259.1| enteropeptidase, light chain (L chain) [Sus scrofa]
Length = 1034
Score = 84.0 bits (206), Expect = 1e-17
Identities = 65/224 (29%), Positives = 111/224 (49%), Gaps = 6/224 (2%)
Frame = +2
Query: 1199 TCGLRQY-KEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAA 1375
+CG +Q +E +I GG + + PW A++ + LCG L+S W++SAA
Sbjct: 786 SCGKKQVAQEVSPKIVGGNDSREGAWPWVVALYYNGQ------LLCGASLVSRDWLVSAA 839
Query: 1376 HCFQER-FPPHHVRVVLG--RTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDNDIALLQLK 1546
HC R P + +LG T L + +++ +++ ++ D+DIA++ L+
Sbjct: 840 HCVYGRNLEPSKWKAILGLHMTSNLTSPQIVTRL-IDEIVINPHYNRRRKDSDIAMMHLE 898
Query: 1547 SDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGK--HEASSPFYSERLKEAHVRLY 1720
+D ++ +CLPE N P C ++G+GK ++ S ++ L+EA V L
Sbjct: 899 FK----VNYTDYIQPICLPEENQVFPPGRICSIAGWGKVIYQGSP---ADILQEADVPLL 951
Query: 1721 PSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
+ C + + IT++M+CAG G D+CQGDSGG
Sbjct: 952 SNEKC-QQQMPEYNITENMMCAGYEEGG------IDSCQGDSGG 988
>ref|NP_001001911.1| kallikrein 1, renal/pancreas/salivary [Sus scrofa]
Length = 263
Score = 83.6 bits (205), Expect = 1e-17
Identities = 65/216 (30%), Positives = 100/216 (46%), Gaps = 8/216 (3%)
Frame = +2
Query: 1229 QFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHC----FQERF 1396
Q RI GG + SHPWQ AI+ + F CGG+L+ WVL+AAHC +Q
Sbjct: 22 QSRIIGGRECEKDSHPWQVAIYHYSS------FQCGGVLVDPKWVLTAAHCKNDNYQVWL 75
Query: 1397 PPHHV--RVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDNDIALLQLKSDSLTCAQ 1570
H++ V + + + F + H + D Y +D+ LL+L+S A+
Sbjct: 76 GRHNLFENEVTAQFFGVTADFPHPGFNLSLLKNHTKADGKDYSHDLMLLRLQSP----AK 131
Query: 1571 ESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYS--ERLKEAHVRLYPSSCCTSK 1744
+DAV+ + LP +L + C+ SG+G E + + ++ + L ++ C
Sbjct: 132 ITDAVKVLELPTQEPEL--GSTCQASGWGSIEPGPDDFEFPDEIQCVELTLLQNTFCADA 189
Query: 1745 HLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
H +T+ MLCAG G D C GDSGG
Sbjct: 190 H--PDKVTESMLCAGYLPGG------KDTCMGDSGG 217
>ref|NP_999083.1| protein C [Sus scrofa]
Length = 459
Score = 83.2 bits (204), Expect = 2e-17
Identities = 96/338 (28%), Positives = 140/338 (41%), Gaps = 25/338 (7%)
Frame = +2
Query: 914 CSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLG 1093
C +P C + C G G +R + G FCL + SN T G
Sbjct: 100 CDSPCCGRGT--CIDGLG-GFRCDCAQGWEGRFCL-----------HEVRFSNCSTENGG 145
Query: 1094 KHNYCRNPDGDTQPWC---HVLKDHKLTWEYCDLPQCVTCGLRQYK-------------- 1222
+YC +G + C + L D L E C G R K
Sbjct: 146 CAHYCLEEEGGRRCACAPGYRLGDDHLQCEPKVRSPCGRLGNRMEKKRKNLKRDTDQVDK 205
Query: 1223 -EPQF--RIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQER 1393
E Q R+ G + PWQ + ++ CG +LI WVL+AAHC +
Sbjct: 206 KEDQIDPRLVNGKQSPWGESPWQVILLDSKKK-----LACGAVLIHVSWVLTAAHCLDDY 260
Query: 1394 FPPHHVRVVLGRTYRLVPGEE-EQAFEVEKYIVHKEFDDDTYDNDIALLQLKSDSLTCAQ 1570
+ V LG Y L E+ E ++++++VH + T DNDIALL+L A
Sbjct: 261 ---KKLTVRLGE-YDLRRREKWEVDLDIKEFLVHPNYTRSTSDNDIALLRLAEP----AT 312
Query: 1571 ESDAVRTVCLPEANLQLPDWT----ECELSGYGKHEASSPFYSERLKEAHVRLYPSSCCT 1738
S + +CLP++ L + T E ++G+G + S L V + P + C
Sbjct: 313 FSQTIVPICLPDSGLSERELTRVGQETVVTGWGYRSEAKTNRSFILNFIKVPVAPHNECV 372
Query: 1739 SKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
+ + NK I+++MLCAG GD DAC+GDSGG
Sbjct: 373 -QAMHNK-ISENMLCAGIL---GDS---RDACEGDSGG 402
Database: RefSeqSP
Posted date: Aug 1, 2006 7:14 PM
Number of letters in database: 434,620
Number of sequences in database: 1040
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,052,404
Number of Sequences: 1040
Number of extensions: 62987
Number of successful extensions: 355
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 218
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 312
length of database: 434,620
effective HSP length: 82
effective length of database: 349,340
effective search space used: 186896900
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqBP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-007176
(1854 letters)
Database: RefSeqBP
33,508 sequences; 16,112,626 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_776571.2| plasminogen activator, tissue [Bos taurus] 914 0.0
Alignment gi|NP_001014868.1| hyaluronan binding protein 2 [Bos taurus] 219 8e-57
Alignment gi|NP_776572.1| plasminogen activator, urokinase [Bos taurus] 218 1e-56
Alignment gi|XP_875628.1| PREDICTED: similar to Coagulation factor XII pr... 216 5e-56
Alignment gi|NP_776376.1| plasminogen [Bos taurus] 187 2e-47
Alignment gi|XP_888406.1| PREDICTED: similar to Coagulation factor XII pr... 184 3e-46
Alignment gi|XP_588610.2| PREDICTED: similar to Coagulation factor XII pr... 180 4e-45
Alignment gi|XP_580402.2| PREDICTED: similar to HGF activator preproprote... 178 1e-44
Alignment gi|XP_888407.1| PREDICTED: similar to Coagulation factor XII pr... 176 6e-44
Alignment gi|NP_001026921.1| hepatocyte growth factor [Bos taurus] 139 1e-32
>ref|NP_776571.2| plasminogen activator, tissue [Bos taurus]
Length = 566
Score = 914 bits (2363), Expect = 0.0
Identities = 413/518 (79%), Positives = 454/518 (87%), Gaps = 3/518 (0%)
Frame = +2
Query: 308 MYALKRELWCVLLLCGAICTSPSQETHXXXXXXXXXXXVTCRDEKTQMIYQQHQSWLRPL 487
M A+K E CVLLLCGA+ TSPSQET+ VTCRD KTQM Y+QH SWLRPL
Sbjct: 2 MSAMKTEFLCVLLLCGAVFTSPSQETYRRLRRGARSYKVTCRDGKTQMTYRQHDSWLRPL 61
Query: 488 LRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCE 667
LRGN+VEHCWC+ G+ QCHSVPV+SCSEP CFNGGTC QA+Y SDFVCQCP GF+G+ CE
Sbjct: 62 LRGNQVEHCWCDGGRAQCHSVPVRSCSEPWCFNGGTCRQALYSSDFVCQCPEGFMGKLCE 121
Query: 668 IDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCR 847
IDA ATCY+DQG+ YRGTWST ESGAEC NWN+SGLA PY+GRRP+A++LGLGNHNYCR
Sbjct: 122 IDATATCYKDQGVAYRGTWSTAESGAECANWNSSGLAMKPYSGRRPNAIRLGLGNHNYCR 181
Query: 848 NPDKDSKPWCYIFKAEKYIPDFCSTPACTKEKEE---CYTGKGLDYRGTRSLTMSGAFCL 1018
NPD+DSKPWCY+FKA KYI +FCSTPAC K EE CYTG GL YRGTRS T SGA CL
Sbjct: 182 NPDQDSKPWCYVFKAGKYISEFCSTPACAKVAEEDGDCYTGNGLAYRGTRSHTKSGASCL 241
Query: 1019 PWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCV 1198
PWNS+ L KIYTAW SNA LGLGKHN+CRNPDGD QPWCHV KD +LTWEYCD+PQCV
Sbjct: 242 PWNSVFLTSKIYTAWKSNAPALGLGKHNHCRNPDGDAQPWCHVWKDRQLTWEYCDVPQCV 301
Query: 1199 TCGLRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAH 1378
TCGLRQYK PQFRIKGGL+ADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAH
Sbjct: 302 TCGLRQYKRPQFRIKGGLFADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAH 361
Query: 1379 CFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDNDIALLQLKSDSL 1558
CFQER+PP H++V LGRTYRLVPGEEEQ FEVEKYI+HKEFDDDTYDNDIALL LKSDSL
Sbjct: 362 CFQERYPPLHLKVFLGRTYRLVPGEEEQTFEVEKYIIHKEFDDDTYDNDIALLHLKSDSL 421
Query: 1559 TCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSSCCT 1738
TCA+ES +VRT+CLP+A+LQLPDWTECELSGYGKHE+SSPF+SERLKEAHVRLYPSS CT
Sbjct: 422 TCARESASVRTICLPDASLQLPDWTECELSGYGKHESSSPFFSERLKEAHVRLYPSSRCT 481
Query: 1739 SKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
S+HLFN+T+T +MLCAGDTRSGGD NLHDACQGDSGG
Sbjct: 482 SQHLFNRTVTNNMLCAGDTRSGGDHTNLHDACQGDSGG 519
>ref|NP_001014868.1| hyaluronan binding protein 2 [Bos taurus]
Length = 558
Score = 219 bits (557), Expect = 8e-57
Identities = 159/470 (33%), Positives = 222/470 (47%), Gaps = 40/470 (8%)
Frame = +2
Query: 563 CSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESG 742
C C +GG CL V + F C+CP F G +C+ + + C + RG T+S
Sbjct: 75 CLSNPCTHGGDCL--VSGATFTCRCPDPFSGNRCQ-NVQNKCKNNP--CGRGDCLITQSP 129
Query: 743 A--ECVNWNTSGLASMPYNGR---------RPDAVKLGLGNHNYCRNPDKDSKPWCYIFK 889
C PY G RP+ + N C + SK C
Sbjct: 130 PYHRCA-------CKHPYRGSDCSRVVPVCRPNPCQ----NGGTCSRQRRRSKFTCAC-- 176
Query: 890 AEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNS 1069
PD C ++CY G YRG S T+ CL WNS +L+ + Y +
Sbjct: 177 -----PDQFKGKLCEIGPDDCYVDDGYSYRGRVSKTIHQHTCLYWNSHLLLQEKYNMFME 231
Query: 1070 NAQTLGLGKHNYCRNPDGDTQPWCHV-LKDHKLTWEYCDLPQCV---------------- 1198
+A+ G+G+HN+CRNPDGD +PWC + + + K+ WEYCD+P C
Sbjct: 232 DAEAHGIGEHNFCRNPDGDKKPWCFIKVNNVKVKWEYCDVPACSALDVANPEGRPTEPLT 291
Query: 1199 ------TCGLRQYKEPQF-RIKGGLYADITSHPWQAAIFVKNRR--SPGERFLCGGILIS 1351
+CG + E + RI GG + HPWQA++ R S + CGG LI
Sbjct: 292 KFPEFGSCGRTEIAEKKVKRIFGGFKSTAGKHPWQASLQTSLRLTVSTPQGHYCGGALIH 351
Query: 1352 SCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVE---KYIVHKEFDDDTYDN 1522
CWVL+AAHC + +++VVLG EQ+F V+ KY + E DD Y N
Sbjct: 352 PCWVLTAAHCTE--IKTKYLKVVLGDQDLTKTEFHEQSFGVQKIFKYSHYIEIDDIPY-N 408
Query: 1523 DIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKE 1702
DIALL+LK CA ES V+TVCLP+ TEC +SG+G E S L +
Sbjct: 409 DIALLKLKPVDGHCALESKYVKTVCLPDG--PFLSGTECYISGWGVTETGEG--SRHLLD 464
Query: 1703 AHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
A V+L ++ C S+ L++ +I +M+CAG+ + G D+CQGDSGG
Sbjct: 465 AKVKLISNTICNSRQLYDHSIDDNMICAGNLQKPG-----QDSCQGDSGG 509
Score = 105 bits (262), Expect = 1e-22
Identities = 57/130 (43%), Positives = 68/130 (52%), Gaps = 1/130 (0%)
Frame = +2
Query: 548 VPVKSCSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWS 727
VPV C C NGGTC + S F C CP F G+ CEI CY D G +YRG S
Sbjct: 149 VPV--CRPNPCQNGGTCSRQRRRSKFTCACPDQFKGKLCEI-GPDDCYVDDGYSYRGRVS 205
Query: 728 TTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYI-FKAEKYI 904
T C+ WN+ L YN DA G+G HN+CRNPD D KPWC+I K
Sbjct: 206 KTIHQHTCLYWNSHLLLQEKYNMFMEDAEAHGIGEHNFCRNPDGDKKPWCFIKVNNVKVK 265
Query: 905 PDFCSTPACT 934
++C PAC+
Sbjct: 266 WEYCDVPACS 275
>ref|NP_776572.1| plasminogen activator, urokinase [Bos taurus]
Length = 433
Score = 218 bits (555), Expect = 1e-56
Identities = 120/317 (37%), Positives = 170/317 (53%), Gaps = 16/317 (5%)
Frame = +2
Query: 950 CYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDT 1129
CY G G YRG + +SG CL W+S ++ K+Y A S+A LGLGKHNYCRNPD
Sbjct: 72 CYQGNGHSYRGKANRDLSGRPCLAWDSPTVLLKMYHAHRSDAIQLGLGKHNYCRNPDNQR 131
Query: 1130 QPWCHVLKDHKLTWEYCDLPQC--------------VTCGLRQYKEPQFRIKGGLYADIT 1267
+PWC+V K ++C + C CG + + P+F+I GG +
Sbjct: 132 RPWCYVQIGLKQFVQFCMVQDCSVGKSPSSPREKEEFQCGQKALR-PRFKIVGGQVTNAE 190
Query: 1268 SHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVP 1447
+ PW AAI+ + R +LCGG LIS CWV+SA HCF + + V LG++
Sbjct: 191 NQPWFAAIY-RRHRGGSITYLCGGSLISPCWVVSATHCFIDHPKKENYIVYLGQSRLNSD 249
Query: 1448 GEEEQAFEVEKYIVHKEFDDDT--YDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQL 1621
E FEVEK I+H+++ ++ + NDIALL++++ CAQ S +++T+CLP +
Sbjct: 250 TRGEMQFEVEKLILHEDYSAESLAHHNDIALLKIRTSRGQCAQPSRSIQTICLPPEHEDA 309
Query: 1622 PDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRS 1801
T CE++G+GK S YS+ LK V L C H + +T MLCA D +
Sbjct: 310 HSRTRCEITGFGKENPSDYRYSDELKMTFVSLVSHEVCQQPHYYGAEVTDKMLCAADPQW 369
Query: 1802 GGDDANLHDACQGDSGG 1852
D+CQGDSGG
Sbjct: 370 E------TDSCQGDSGG 380
Score = 122 bits (307), Expect = 7e-28
Identities = 62/158 (39%), Positives = 83/158 (52%), Gaps = 10/158 (6%)
Frame = +2
Query: 521 NDGQTQCHSVPVKS-CSEPRCFNGGTCLQAVYFSDFV-CQCPVGFIGRQCEIDARATCYE 694
+DG + H +S C C NGG C+ YFS+ C CP F G CEID TCY+
Sbjct: 18 SDGSNEVHKESGESNCG---CLNGGKCVTYKYFSNIQRCSCPKKFQGEHCEIDTSKTCYQ 74
Query: 695 DQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPW 874
G +YRG + SG C+ W++ + Y+ R DA++LGLG HNYCRNPD +PW
Sbjct: 75 GNGHSYRGKANRDLSGRPCLAWDSPTVLLKMYHAHRSDAIQLGLGKHNYCRNPDNQRRPW 134
Query: 875 CYIFKAEKYIPDFC--------STPACTKEKEECYTGK 964
CY+ K FC +P+ +EKEE G+
Sbjct: 135 CYVQIGLKQFVQFCMVQDCSVGKSPSSPREKEEFQCGQ 172
>ref|XP_875628.1| PREDICTED: similar to Coagulation factor XII precursor (Hageman
factor) (HAF) isoform 2 [Bos taurus]
Length = 605
Score = 216 bits (550), Expect = 5e-56
Identities = 153/486 (31%), Positives = 222/486 (45%), Gaps = 11/486 (2%)
Frame = +2
Query: 428 CRDEKTQMIYQQHQSWLRPLLRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQA 607
C + + + +++ W R L V C C QC + + C C NGG+CLQA
Sbjct: 135 CFEPQFFRFFHENEIWHR--LEPAGVVKCQCKGPNAQCKPLASQVCRTNPCLNGGSCLQA 192
Query: 608 VYFSDFVCQCPVGFIGRQCEIDARATCYEDQ--GITYRGTWSTTESGAECVNWNTSGLAS 781
+C+C F GR C++D +A+CY+D+ G++YRG TT SGA C +W +
Sbjct: 193 E--GHRLCRCAPSFAGRLCDVDLKASCYDDRDRGLSYRGMAGTTLSGAPCQSWASEATY- 249
Query: 782 MPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPACT----KEKEE 949
+N + GLG+H +CRNPD D++PWC+I+K ++ ++C C E
Sbjct: 250 --WNVTAEQVLNWGLGDHAFCRNPDNDTRPWCFIWKGDRLSWNYCRLAPCQAAAGHEHFP 307
Query: 950 CYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDT 1129
+ L + + T S A+ P T W S G P G
Sbjct: 308 LPSPSALQKPESTTQTPSSAWAPP-----------TGWCSPTPLASGG-------PGG-- 347
Query: 1130 QPWCHVLKDHKLTWEYCDLPQCVTCG--LRQYKEPQFRIKGGLYADITSHPWQAAIFVKN 1303
CG LR++ R+ GGL A +HP+ AA++
Sbjct: 348 ------------------------CGQRLRKWLSSLNRVVGGLVALPGAHPYIAALY--- 380
Query: 1304 RRSPGERFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKY 1483
++ C G LI+ CWVL+AAHC Q R P + VVLG+ E+ Q V Y
Sbjct: 381 ----WDQHFCAGSLIAPCWVLTAAHCLQNRPAPKELTVVLGQDRHNQSCEQCQTLAVRDY 436
Query: 1484 IVHKEFDDDTYDNDIALLQL-KSDSLTCAQESDAVRTVCLPE--ANLQLPDWTECELSGY 1654
+H+ F TY +D+AL++L +S CA S V+ VCLP A + CE++G+
Sbjct: 437 RLHEAFSPITYQHDLALVRLQESADGCCAHPSPFVQPVCLPSTAARPAESEAAVCEVAGW 496
Query: 1655 GKHEASSPFYSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDAC 1834
G H+ YS L+EA V L C++ + T+ MLCAG G DAC
Sbjct: 497 G-HQFEGGEYSSFLQEAQVPLIDPQRCSAPDVHGAAFTQGMLCAGFLEGG------TDAC 549
Query: 1835 QGDSGG 1852
QGDSGG
Sbjct: 550 QGDSGG 555
>ref|NP_776376.1| plasminogen [Bos taurus]
Length = 812
Score = 187 bits (476), Expect = 2e-47
Identities = 136/413 (32%), Positives = 194/413 (46%), Gaps = 24/413 (5%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNG-RRPDAVKLGLGNHNYCRNPDKD 862
CY G +YRGT STT +G +C +W++ P+ + P+ NYCRNPD D
Sbjct: 384 CYHGNGQSYRGTSSTTITGRKCQSWSSM----TPHRHLKTPENYPNAGLTMNYCRNPDAD 439
Query: 863 SKPWCYIFKAEKYIPDFCSTPACTKEKEE-----------------CYTGKGLDYRGTRS 991
PWCY + +FC+ C++ E+ C G G YRG ++
Sbjct: 440 KSPWCYTTDP-RVRWEFCNLKKCSETPEQVPAAPQAPGVENPPEADCMIGTGKSYRGKKA 498
Query: 992 LTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ-PWCHVLKDHKLT 1168
T++G C W + +N Q+ GL + NYCRNPDGD PWC+ + K
Sbjct: 499 TTVAGVPCQEWAAQEPHQHSIFTPETNPQS-GL-ERNYCRNPDGDVNGPWCYTMNPRK-P 555
Query: 1169 WEYCDLPQCVT---CGLRQY--KEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLC 1333
++YCD+PQC + CG + K+ RI GG + S PWQ ++ RRS R C
Sbjct: 556 FDYCDVPQCESSFDCGKPKVEPKKCSGRIVGGCVSKPHSWPWQVSL----RRS--SRHFC 609
Query: 1334 GGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDT 1513
GG LIS WVL+AAHC +V+LG E+ + V++ V + F + +
Sbjct: 610 GGTLISPKWVLTAAHCLDNILALSFYKVILG-----AHNEKVREQSVQEIPVSRLFREPS 664
Query: 1514 YDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSER 1693
DIALL+L ++ + V CLP N + TEC ++G+G E F
Sbjct: 665 -QADIALLKLSRPAIITKE----VIPACLPPPNYMVAARTECYITGWG--ETQGTFGEGL 717
Query: 1694 LKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
LKEAH+ + + C + + LCAG G D+CQGDSGG
Sbjct: 718 LKEAHLPVIENKVCNRNEYLDGRVKPTELCAGHLIGG------TDSCQGDSGG 764
Score = 116 bits (291), Expect = 5e-26
Identities = 66/174 (37%), Positives = 88/174 (50%), Gaps = 2/174 (1%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGR-RPDAVKLGLGNHNYCRNPDKD 862
C G TYRGT + T+SG C W+ A+ P+ + P+ L NYCRNPD D
Sbjct: 110 CKTGNGQTYRGTTAETKSGVTCQKWS----ATSPHVPKFSPEKFPLAGLEENYCRNPDND 165
Query: 863 SK-PWCYIFKAEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVL 1039
PWCY +K D+C P C +++C G +Y G + TMSG C W+S
Sbjct: 166 ENGPWCYTTDPDKRY-DYCDIPEC---EDKCMHCSGENYEGKIAKTMSGRDCQAWDSQSP 221
Query: 1040 MGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVT 1201
Y + L K NYCRNPDG+ +PWC D + WE+CD+P+C T
Sbjct: 222 HAHGYIPSKFPNKNL---KMNYCRNPDGEPRPWCFT-TDPQKRWEFCDIPRCTT 271
Score = 113 bits (282), Expect = 6e-25
Identities = 64/189 (33%), Positives = 90/189 (47%), Gaps = 19/189 (10%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPY-NGRRPDAVKLGLGNHNYCRNPDKD 862
C + G Y GT + TESG C W+ P+ + R P+ NYCRNP+ +
Sbjct: 282 CLKGTGKNYGGTVAVTESGHTCQRWSEQ----TPHKHNRTPENFPCKNLEENYCRNPNGE 337
Query: 863 SKPWCYIFKAEKYIPDFCSTPAC------------------TKEKEECYTGKGLDYRGTR 988
PWCY +E ++C+ P+C T ++CY G G YRGT
Sbjct: 338 KAPWCYTTNSEVRW-EYCTIPSCESSPLSTERMDVPVPPEQTPVPQDCYHGNGQSYRGTS 396
Query: 989 SLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLT 1168
S T++G C W+S+ + T N GL NYCRNPD D PWC+ D ++
Sbjct: 397 STTITGRKCQSWSSMTPHRHLKTP--ENYPNAGL-TMNYCRNPDADKSPWCYT-TDPRVR 452
Query: 1169 WEYCDLPQC 1195
WE+C+L +C
Sbjct: 453 WEFCNLKKC 461
Score = 62.4 bits (150), Expect = 1e-09
Identities = 32/84 (38%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +2
Query: 947 ECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGD 1126
EC TG G YRGT + T SG C W++ ++ L + NYCRNPD D
Sbjct: 109 ECKTGNGQTYRGTTAETKSGVTCQKWSA---TSPHVPKFSPEKFPLAGLEENYCRNPDND 165
Query: 1127 TQ-PWCHVLKDHKLTWEYCDLPQC 1195
PWC+ K ++YCD+P+C
Sbjct: 166 ENGPWCYTTDPDK-RYDYCDIPEC 188
Score = 51.6 bits (122), Expect = 2e-06
Identities = 31/87 (35%), Positives = 38/87 (43%), Gaps = 3/87 (3%)
Frame = +2
Query: 680 ATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGR--RPDAVKLGLGNHNYCRNP 853
A C G +YRG +TT +G C W A P+ P+ NYCRNP
Sbjct: 483 ADCMIGTGKSYRGKKATTVAGVPCQEW----AAQEPHQHSIFTPETNPQSGLERNYCRNP 538
Query: 854 DKD-SKPWCYIFKAEKYIPDFCSTPAC 931
D D + PWCY K D+C P C
Sbjct: 539 DGDVNGPWCYTMNPRKPF-DYCDVPQC 564
>ref|XP_888406.1| PREDICTED: similar to Coagulation factor XII precursor (Hageman
factor) (HAF) isoform 3 [Bos taurus]
Length = 593
Score = 184 bits (466), Expect = 3e-46
Identities = 146/477 (30%), Positives = 198/477 (41%), Gaps = 52/477 (10%)
Frame = +2
Query: 578 CFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITY---RGTWSTTESGAE 748
C GGTC+ C C F G+ C+ + C+E Q + W E
Sbjct: 104 CQKGGTCVNMP--DGPRCICADHFTGKHCQ---KEKCFEPQFFRFFHENEIWHRLEP--- 155
Query: 749 CVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYI---PDFCS 919
+G+ G L CR + C + + P F
Sbjct: 156 ------AGVVKCQCKGPNAQCKPLA---SQVCRTNPCLNGGSCLQAEGHRLCRCAPSFAG 206
Query: 920 TPACTKEKEECYTGK--GLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTL--- 1084
K CY + GL YRG T+SGA C W S T WN A+ +
Sbjct: 207 RLCDVDLKASCYDDRDRGLSYRGMAGTTLSGAPCQSWASEA------TYWNVTAEQVLNW 260
Query: 1085 GLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVT--------------------- 1201
GLG H +CRNPD DT+PWC + K +L+W YC L C
Sbjct: 261 GLGDHAFCRNPDNDTRPWCFIWKGDRLSWNYCRLAPCQAAAGHEHFPLPSPSALQKPEST 320
Query: 1202 ---------------CG--LRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFL 1330
CG LR++ R+ GGL A +HP+ AA++ ++
Sbjct: 321 TQTPLPSLTSGSPGGCGQRLRKWLSSLNRVVGGLVALPGAHPYIAALY-------WDQHF 373
Query: 1331 CGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDD 1510
C G LI+ CWVL+AAHC Q R P + VVLG+ E+ Q V Y +H+ F
Sbjct: 374 CAGSLIAPCWVLTAAHCLQNRPAPKELTVVLGQDRHNQSCEQCQTLAVRDYRLHEAFSPI 433
Query: 1511 TYDNDIALLQL-KSDSLTCAQESDAVRTVCLPE--ANLQLPDWTECELSGYGKHEASSPF 1681
TY +D+AL++L +S CA S V+ VCLP A + CE++G+G H+
Sbjct: 434 TYQHDLALVRLQESADGCCAHPSPFVQPVCLPSTAARPAESEAAVCEVAGWG-HQFEGGE 492
Query: 1682 YSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
YS L+EA V L C++ + T+ MLCAG G DACQGDSGG
Sbjct: 493 YSSFLQEAQVPLIDPQRCSAPDVHGAAFTQGMLCAGFLEGG------TDACQGDSGG 543
Score = 120 bits (300), Expect = 5e-27
Identities = 58/170 (34%), Positives = 91/170 (53%), Gaps = 2/170 (1%)
Frame = +2
Query: 428 CRDEKTQMIYQQHQSWLRPLLRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQA 607
C + + + +++ W R L V C C QC + + C C NGG+CLQA
Sbjct: 135 CFEPQFFRFFHENEIWHR--LEPAGVVKCQCKGPNAQCKPLASQVCRTNPCLNGGSCLQA 192
Query: 608 VYFSDFVCQCPVGFIGRQCEIDARATCYEDQ--GITYRGTWSTTESGAECVNWNTSGLAS 781
+C+C F GR C++D +A+CY+D+ G++YRG TT SGA C +W +
Sbjct: 193 E--GHRLCRCAPSFAGRLCDVDLKASCYDDRDRGLSYRGMAGTTLSGAPCQSWASEATY- 249
Query: 782 MPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPAC 931
+N + GLG+H +CRNPD D++PWC+I+K ++ ++C C
Sbjct: 250 --WNVTAEQVLNWGLGDHAFCRNPDNDTRPWCFIWKGDRLSWNYCRLAPC 297
>ref|XP_588610.2| PREDICTED: similar to Coagulation factor XII precursor (Hageman
factor) (HAF) isoform 1 [Bos taurus]
Length = 603
Score = 180 bits (456), Expect = 4e-45
Identities = 146/487 (29%), Positives = 198/487 (40%), Gaps = 62/487 (12%)
Frame = +2
Query: 578 CFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITY---RGTWSTTESGAE 748
C GGTC+ C C F G+ C+ + C+E Q + W E
Sbjct: 104 CQKGGTCVNMP--DGPRCICADHFTGKHCQ---KEKCFEPQFFRFFHENEIWHRLEP--- 155
Query: 749 CVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYI---PDFCS 919
+G+ G L CR + C + + P F
Sbjct: 156 ------AGVVKCQCKGPNAQCKPLA---SQVCRTNPCLNGGSCLQAEGHRLCRCAPSFAG 206
Query: 920 TPACTKEKEECYTGK--GLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTL--- 1084
K CY + GL YRG T+SGA C W S T WN A+ +
Sbjct: 207 RLCDVDLKASCYDDRDRGLSYRGMAGTTLSGAPCQSWASEA------TYWNVTAEQVLNW 260
Query: 1085 GLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVT--------------------- 1201
GLG H +CRNPD DT+PWC + K +L+W YC L C
Sbjct: 261 GLGDHAFCRNPDNDTRPWCFIWKGDRLSWNYCRLAPCQAAAGHEHFPLPSPSALQKPEST 320
Query: 1202 -------------------------CG--LRQYKEPQFRIKGGLYADITSHPWQAAIFVK 1300
CG LR++ R+ GGL A +HP+ AA++
Sbjct: 321 TQTPLPSLTSGWCSPTPLASGGPGGCGQRLRKWLSSLNRVVGGLVALPGAHPYIAALY-- 378
Query: 1301 NRRSPGERFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEK 1480
++ C G LI+ CWVL+AAHC Q R P + VVLG+ E+ Q V
Sbjct: 379 -----WDQHFCAGSLIAPCWVLTAAHCLQNRPAPKELTVVLGQDRHNQSCEQCQTLAVRD 433
Query: 1481 YIVHKEFDDDTYDNDIALLQL-KSDSLTCAQESDAVRTVCLPE--ANLQLPDWTECELSG 1651
Y +H+ F TY +D+AL++L +S CA S V+ VCLP A + CE++G
Sbjct: 434 YRLHEAFSPITYQHDLALVRLQESADGCCAHPSPFVQPVCLPSTAARPAESEAAVCEVAG 493
Query: 1652 YGKHEASSPFYSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDA 1831
+G H+ YS L+EA V L C++ + T+ MLCAG G DA
Sbjct: 494 WG-HQFEGGEYSSFLQEAQVPLIDPQRCSAPDVHGAAFTQGMLCAGFLEGG------TDA 546
Query: 1832 CQGDSGG 1852
CQGDSGG
Sbjct: 547 CQGDSGG 553
Score = 120 bits (300), Expect = 5e-27
Identities = 58/170 (34%), Positives = 91/170 (53%), Gaps = 2/170 (1%)
Frame = +2
Query: 428 CRDEKTQMIYQQHQSWLRPLLRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQA 607
C + + + +++ W R L V C C QC + + C C NGG+CLQA
Sbjct: 135 CFEPQFFRFFHENEIWHR--LEPAGVVKCQCKGPNAQCKPLASQVCRTNPCLNGGSCLQA 192
Query: 608 VYFSDFVCQCPVGFIGRQCEIDARATCYEDQ--GITYRGTWSTTESGAECVNWNTSGLAS 781
+C+C F GR C++D +A+CY+D+ G++YRG TT SGA C +W +
Sbjct: 193 E--GHRLCRCAPSFAGRLCDVDLKASCYDDRDRGLSYRGMAGTTLSGAPCQSWASEATY- 249
Query: 782 MPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPAC 931
+N + GLG+H +CRNPD D++PWC+I+K ++ ++C C
Sbjct: 250 --WNVTAEQVLNWGLGDHAFCRNPDNDTRPWCFIWKGDRLSWNYCRLAPC 297
>ref|XP_580402.2| PREDICTED: similar to HGF activator preproprotein [Bos taurus]
Length = 577
Score = 178 bits (452), Expect = 1e-44
Identities = 136/475 (28%), Positives = 193/475 (40%), Gaps = 45/475 (9%)
Frame = +2
Query: 563 CSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGT---WSTT 733
C+ C +GG+C C CP F G+ C + C+++ Y W+
Sbjct: 111 CASGPCLHGGSCSSTQDPESHHCTCPAAFTGQDCGTEK---CFDESRYEYLEPGERWARV 167
Query: 734 ESG----AECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKY 901
G EC + G R H C + + C++ A
Sbjct: 168 HQGRVEQCECAG------GQIRCEGTR----------HTACLSSPCLNGGSCHLIVATGT 211
Query: 902 I-----PDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWN 1066
PD+ + C+ G G +YRG S S + L+L
Sbjct: 212 TVCACPPDYAGRLCNIVPAQRCFVGTGTEYRGVASTQASSS-----PPLLL--------- 257
Query: 1067 SNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCV---------------- 1198
NPD D +PWC+V+KD L+WEYC L C
Sbjct: 258 ---------------NPDKDERPWCYVVKDSALSWEYCRLAACESLARIQPPPTEALLTL 302
Query: 1199 ------------TCGLRQYKEPQFR--IKGGLYADITSHPWQAAIFVKNRRSPGERFLCG 1336
TCG R K R I GG + SHPW AAI++ N C
Sbjct: 303 PGPTAAGPAGRQTCGKRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGNN-------FCA 355
Query: 1337 GILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDD-DT 1513
G L+ +CWV+SAAHCF P V VVLG+ + + Q F +EKYI + + +
Sbjct: 356 GSLVHTCWVVSAAHCFSNSPPRESVSVVLGQHFFNRTTDVTQTFGIEKYIPYPLYSVFNP 415
Query: 1514 YDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSER 1693
D+D+ L++L+ CA S V+ +CLPE P +C+++G+G + + YS
Sbjct: 416 SDHDLVLIRLEKKGERCAVRSQFVQPICLPEPGSSFPPGHKCQIAGWGHQDENVSGYSPS 475
Query: 1694 LKEAHVRLYPSSCCTSKHLFNKTITKHMLCAG--DTRSGGDDANLHDACQGDSGG 1852
L+EA V L C+S ++ I+ +MLCAG D RS DACQGDSGG
Sbjct: 476 LREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCRS--------DACQGDSGG 522
Score = 84.3 bits (207), Expect = 3e-16
Identities = 51/168 (30%), Positives = 64/168 (38%)
Frame = +2
Query: 428 CRDEKTQMIYQQHQSWLRPLLRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQA 607
C DE + + W R + RVE C C GQ +C +C C NGG+C
Sbjct: 149 CFDESRYEYLEPGERWAR--VHQGRVEQCECAGGQIRCEGTRHTACLSSPCLNGGSCHLI 206
Query: 608 VYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMP 787
V VC CP + GR C I C+ G YRG ST S +S P
Sbjct: 207 VATGTTVCACPPDYAGRLCNIVPAQRCFVGTGTEYRGVASTQAS------------SSPP 254
Query: 788 YNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPAC 931
NPDKD +PWCY+ K ++C AC
Sbjct: 255 -----------------LLLNPDKDERPWCYVVKDSALSWEYCRLAAC 285
>ref|XP_888407.1| PREDICTED: similar to Coagulation factor XII precursor (Hageman
factor) (HAF) isoform 4 [Bos taurus]
Length = 610
Score = 176 bits (446), Expect = 6e-44
Identities = 147/494 (29%), Positives = 200/494 (40%), Gaps = 69/494 (13%)
Frame = +2
Query: 578 CFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITY---RGTWSTTESGAE 748
C GGTC+ C C F G+ C+ + C+E Q + W E
Sbjct: 104 CQKGGTCVNMP--DGPRCICADHFTGKHCQ---KEKCFEPQFFRFFHENEIWHRLEP--- 155
Query: 749 CVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYI---PDFCS 919
+G+ G L CR + C + + P F
Sbjct: 156 ------AGVVKCQCKGPNAQCKPLA---SQVCRTNPCLNGGSCLQAEGHRLCRCAPSFAG 206
Query: 920 TPACTKEKEECYTGK--GLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTL--- 1084
K CY + GL YRG T+SGA C W S T WN A+ +
Sbjct: 207 RLCDVDLKASCYDDRDRGLSYRGMAGTTLSGAPCQSWASEA------TYWNVTAEQVLNW 260
Query: 1085 GLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDL----------------------PQCV 1198
GLG H +CRNPD DT+PWC + K +L+W YC L P+
Sbjct: 261 GLGDHAFCRNPDNDTRPWCFIWKGDRLSWNYCRLAPCQAAAGHEHFPLPSPSALQKPEST 320
Query: 1199 T-------------------------------CG--LRQYKEPQFRIKGGLYADITSHPW 1279
T CG LR++ R+ GGL A +HP+
Sbjct: 321 TQTPLPSLTSGTWAPPTGWCSPTPLASGGPGGCGQRLRKWLSSLNRVVGGLVALPGAHPY 380
Query: 1280 QAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEE 1459
AA++ ++ C G LI+ CWVL+AAHC Q R P + VVLG+ E+
Sbjct: 381 IAALY-------WDQHFCAGSLIAPCWVLTAAHCLQNRPAPKELTVVLGQDRHNQSCEQC 433
Query: 1460 QAFEVEKYIVHKEFDDDTYDNDIALLQL-KSDSLTCAQESDAVRTVCLPE--ANLQLPDW 1630
Q V Y +H+ F TY +D+AL++L +S CA S V+ VCLP A +
Sbjct: 434 QTLAVRDYRLHEAFSPITYQHDLALVRLQESADGCCAHPSPFVQPVCLPSTAARPAESEA 493
Query: 1631 TECELSGYGKHEASSPFYSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGD 1810
CE++G+G H+ YS L+EA V L C++ + T+ MLCAG G
Sbjct: 494 AVCEVAGWG-HQFEGGEYSSFLQEAQVPLIDPQRCSAPDVHGAAFTQGMLCAGFLEGG-- 550
Query: 1811 DANLHDACQGDSGG 1852
DACQGDSGG
Sbjct: 551 ----TDACQGDSGG 560
Score = 120 bits (300), Expect = 5e-27
Identities = 58/170 (34%), Positives = 91/170 (53%), Gaps = 2/170 (1%)
Frame = +2
Query: 428 CRDEKTQMIYQQHQSWLRPLLRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQA 607
C + + + +++ W R L V C C QC + + C C NGG+CLQA
Sbjct: 135 CFEPQFFRFFHENEIWHR--LEPAGVVKCQCKGPNAQCKPLASQVCRTNPCLNGGSCLQA 192
Query: 608 VYFSDFVCQCPVGFIGRQCEIDARATCYEDQ--GITYRGTWSTTESGAECVNWNTSGLAS 781
+C+C F GR C++D +A+CY+D+ G++YRG TT SGA C +W +
Sbjct: 193 E--GHRLCRCAPSFAGRLCDVDLKASCYDDRDRGLSYRGMAGTTLSGAPCQSWASEATY- 249
Query: 782 MPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPAC 931
+N + GLG+H +CRNPD D++PWC+I+K ++ ++C C
Sbjct: 250 --WNVTAEQVLNWGLGDHAFCRNPDNDTRPWCFIWKGDRLSWNYCRLAPC 297
>ref|NP_001026921.1| hepatocyte growth factor [Bos taurus]
Length = 730
Score = 139 bits (349), Expect = 1e-32
Identities = 106/410 (25%), Positives = 172/410 (41%), Gaps = 21/410 (5%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPY-NGRRPDAVKLGLGNHNYCRNPDKD 862
C + QG YRGT +T +G C W++ P+ + P+ K NYCRNPD
Sbjct: 305 CIQGQGEGYRGTINTIWNGIPCQRWDSQ----YPHQHDITPENFKCKDLRENYCRNPDGA 360
Query: 863 SKPWCYIFKAEKYIPDFCSTPAC-TKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVL 1039
PWC+ + P C ++CY G G +Y G+ S T SG C W+ +
Sbjct: 361 ESPWCFTTDPNIRVGYCSQIPKCDVSSGQDCYRGNGKNYMGSLSKTRSGLTCSMWDKNME 420
Query: 1040 MGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ-PWCHVLKDHKLTWEYCDLPQC------- 1195
+ W +A L NYCRNPD D PWC+ + + W+YC + +C
Sbjct: 421 DLHRHIFWEPDATKL---NKNYCRNPDDDAHGPWCYT-GNPLIPWDYCPISRCEGDTTPT 476
Query: 1196 --------VTCGLRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILIS 1351
++C K Q R+ G+ T+ W ++ +N+ +CGG LI
Sbjct: 477 IVNLDHPVISCA----KTKQLRVVNGI-PTRTNVGWMVSLKYRNKH------ICGGSLIK 525
Query: 1352 SCWVLSAAHCFQER---FPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDN 1522
W+L+A CF R + + + + + +Q V + + E +
Sbjct: 526 ESWILTARQCFPSRNKDLKDYEAWLGIHDVHGRGDEKRKQVLNVTQLVYGPE------GS 579
Query: 1523 DIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKE 1702
D+ LL+L ++ D V T+ LP +P+ T C + G+G + L+
Sbjct: 580 DLVLLKLARPAIL----DDFVSTIDLPNYGCTIPEKTTCSVYGWGYTGLINS--DGLLRV 633
Query: 1703 AHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
AH+ + + C+ H T+ + +CA G + + C+GD GG
Sbjct: 634 AHLYIMGNEKCSQYHQGKVTLNESEICA------GAENIVSGPCEGDYGG 677
Score = 91.7 bits (226), Expect = 2e-18
Identities = 58/175 (33%), Positives = 81/175 (46%), Gaps = 5/175 (2%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTS---GLASMPYNGRRPDAVKLGLGNHNYCRNP- 853
C +G +Y+GT S T+SG +C WN+ + +P + R D NYCRNP
Sbjct: 128 CIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDL------QENYCRNPR 181
Query: 854 DKDSKPWCYIFKAE-KYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNS 1030
++ PWC+ E +Y + C P C++ EC T G YRG T +G C W+
Sbjct: 182 GEEGGPWCFTSNPEVRY--EVCDIPQCSEV--ECMTCNGESYRGPMDHTETGKICQRWDH 237
Query: 1031 LVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQC 1195
+ + NYCRNPDG +PWC+ L D WEYC + C
Sbjct: 238 QTPHRHKFLPERYPDKGFD---DNYCRNPDGKPRPWCYTL-DPDTPWEYCAIKMC 288
Score = 87.0 bits (214), Expect = 4e-17
Identities = 70/227 (30%), Positives = 92/227 (40%), Gaps = 16/227 (7%)
Frame = +2
Query: 563 CSEPRCFNGG----TCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWST 730
C PR GG T V + VC P QC + C G +YRG
Sbjct: 177 CRNPRGEEGGPWCFTSNPEVRYE--VCDIP------QC---SEVECMTCNGESYRGPMDH 225
Query: 731 TESGAECVNWNTSGLASMPYNGRR-PDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIP 907
TE+G C W+ + R PD G + NYCRNPD +PWCY +
Sbjct: 226 TETGKICQRWDHQTPHRHKFLPERYPDK---GFDD-NYCRNPDGKPRPWCYTLDPDTPW- 280
Query: 908 DFCSTPACTK----------EKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT 1057
++C+ C + EC G+G YRGT + +G C W+S T
Sbjct: 281 EYCAIKMCAHSTMNDTDLPMQTTECIQGQGEGYRGTINTIWNGIPCQRWDSQYPHQHDIT 340
Query: 1058 AWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYC-DLPQC 1195
N + L + NYCRNPDG PWC D + YC +P+C
Sbjct: 341 PENFKCKDL---RENYCRNPDGAESPWCFT-TDPNIRVGYCSQIPKC 383
Score = 70.1 bits (170), Expect = 6e-12
Identities = 38/106 (35%), Positives = 55/106 (51%), Gaps = 6/106 (5%)
Frame = +2
Query: 950 CYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDT 1129
C GKG Y+GT S+T SG C PWNS++ + + + L + NYCRNP G+
Sbjct: 128 CIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDL---QENYCRNPRGEE 184
Query: 1130 -QPWCHVLKDHKLTWEYCDLPQ-----CVTCGLRQYKEPQFRIKGG 1249
PWC + ++ +E CD+PQ C+TC Y+ P + G
Sbjct: 185 GGPWCFT-SNPEVRYEVCDIPQCSEVECMTCNGESYRGPMDHTETG 229
Score = 62.0 bits (149), Expect = 2e-09
Identities = 35/93 (37%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 659 QCEIDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHN 838
+C++ + CY G Y G+ S T SG C W+ + + PDA KL N N
Sbjct: 382 KCDVSSGQDCYRGNGKNYMGSLSKTRSGLTCSMWDKNMEDLHRHIFWEPDATKL---NKN 438
Query: 839 YCRNPDKDSK-PWCYIFKAEKYIP-DFCSTPAC 931
YCRNPD D+ PWCY IP D+C C
Sbjct: 439 YCRNPDDDAHGPWCY--TGNPLIPWDYCPISRC 469
Database: RefSeqBP
Posted date: Aug 1, 2006 7:14 PM
Number of letters in database: 16,112,626
Number of sequences in database: 33,508
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,952,046
Number of Sequences: 33508
Number of extensions: 2505067
Number of successful extensions: 12198
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 7565
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11656
length of database: 16,112,626
effective HSP length: 107
effective length of database: 12,527,270
effective search space used: 6388907700
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqCP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-007176
(1854 letters)
Database: RefSeqCP
33,732 sequences; 19,266,565 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|XP_539955.2| PREDICTED: similar to Tissue-type plasminogen a... 852 0.0
Alignment gi|XP_850538.1| PREDICTED: hepatocyte growth factor activator i... 229 9e-60
Alignment gi|XP_861645.1| PREDICTED: hepatocyte growth factor activator i... 229 9e-60
Alignment gi|NP_001026985.1| HGF activator [Canis familiaris] 229 9e-60
Alignment gi|XP_535016.2| PREDICTED: similar to hyaluronan binding protei... 227 3e-59
Alignment gi|XP_536394.2| PREDICTED: similar to urokinase plasminogen act... 219 7e-57
Alignment gi|XP_533468.2| PREDICTED: similar to Plasminogen precursor [Ca... 192 7e-49
Alignment gi|XP_546206.2| PREDICTED: similar to Coagulation factor XII pr... 184 3e-46
Alignment gi|NP_001002964.1| hepatocyte growth factor [Canis familiaris] 141 2e-33
Alignment gi|XP_541884.2| PREDICTED: similar to macrophage stimulating 1 ... 132 1e-30
>ref|XP_539955.2| PREDICTED: similar to Tissue-type plasminogen activator precursor
(tPA) (t-PA) (t-plasminogen activator) [Canis familiaris]
Length = 560
Score = 852 bits (2202), Expect = 0.0
Identities = 386/477 (80%), Positives = 421/477 (88%), Gaps = 1/477 (0%)
Frame = +2
Query: 425 TCRDEKTQMIYQQHQSWLRPLLRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQ 604
+CRDEKTQ Y +SWLRP LRGNRVE+C C G+ QCHSVPV+ CSEPRCFNGGTC Q
Sbjct: 37 SCRDEKTQTQYGPSESWLRPGLRGNRVEYCRCAGGRPQCHSVPVRGCSEPRCFNGGTCRQ 96
Query: 605 AVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASM 784
A+YF+DFVCQCP GF+G++CEIDA ATCY+DQGI+YRGTWST ESGAEC NWN+S LA
Sbjct: 97 ALYFADFVCQCPEGFLGKRCEIDAGATCYKDQGISYRGTWSTAESGAECANWNSSALALK 156
Query: 785 PYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPACTKEK-EECYTG 961
PY+ RRP AV+LGLG+HNYCRNPD D +PWCY+FKA KY +FCSTPAC KEK E+CY G
Sbjct: 157 PYSARRPHAVRLGLGSHNYCRNPDGDLRPWCYVFKAGKYSTEFCSTPACPKEKNEDCYFG 216
Query: 962 KGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWC 1141
KGL YRGT S T SG CLPWNS VL GK YT W +NAQ LGLG HNYCRNPDGD +PWC
Sbjct: 217 KGLAYRGTYSFTTSGTPCLPWNSRVLAGKFYTTWKTNAQALGLGSHNYCRNPDGDAKPWC 276
Query: 1142 HVLKDHKLTWEYCDLPQCVTCGLRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGE 1321
HVLKD KLTWEYCD+PQC TCGLR YK+PQFRIKGGLYADITSHPWQAAIFVKNRRSPGE
Sbjct: 277 HVLKDRKLTWEYCDVPQCSTCGLRHYKQPQFRIKGGLYADITSHPWQAAIFVKNRRSPGE 336
Query: 1322 RFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEF 1501
RF CGGILISSCWVLSAAHCFQER+PPH ++VVLGRTYR VPGE+EQ FEVEKYI HKEF
Sbjct: 337 RFFCGGILISSCWVLSAAHCFQERYPPHQLKVVLGRTYREVPGEKEQKFEVEKYITHKEF 396
Query: 1502 DDDTYDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPF 1681
DDDTY+NDIALL+L+SDSL CAQESDAVRT CLPEA+LQLPDWTECELSGYGKHEASSPF
Sbjct: 397 DDDTYNNDIALLKLQSDSLHCAQESDAVRTACLPEADLQLPDWTECELSGYGKHEASSPF 456
Query: 1682 YSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
YSERLKEAHVRLYPSS CTS+HLFNKTIT +MLCAGDTRSGG+ ANLHDACQGDSGG
Sbjct: 457 YSERLKEAHVRLYPSSRCTSRHLFNKTITNNMLCAGDTRSGGNQANLHDACQGDSGG 513
>ref|XP_850538.1| PREDICTED: hepatocyte growth factor activator isoform 1 [Canis
familiaris]
Length = 654
Score = 229 bits (583), Expect = 9e-60
Identities = 154/476 (32%), Positives = 221/476 (46%), Gaps = 45/476 (9%)
Frame = +2
Query: 560 SCSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYED---QGITYRGTWST 730
SC+ C NGG+C + C CP+ F GR C+ + C+++ + + W+
Sbjct: 161 SCASSPCLNGGSCSHTQDPGSYHCTCPMAFTGRNCDTEK---CFDETRYEHLEAGDRWAR 217
Query: 731 TESG----AECVNW--------NTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPW 874
G EC +T+ L+S NG + + G C P +
Sbjct: 218 VSQGQVEQCECAGGQIRCEGTRHTACLSSPCLNGGTCHLI-VATGT-TVCSCPPGHAGRL 275
Query: 875 CYIFKAEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIY 1054
C I +++ C+ G G +YRG S SG CL WNS +L +++
Sbjct: 276 CNIVPSQR-----------------CFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELH 318
Query: 1055 TAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQC------------- 1195
A LGLG H YCRNPD D +PWC+V+KD L+WEYC L C
Sbjct: 319 VDSVGAAALLGLGPHAYCRNPDKDERPWCYVVKDSALSWEYCRLAACESLARIPSLTTAV 378
Query: 1196 ------------VTCGLRQYKEP--QFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLC 1333
TCG R K + RI GG + SHPW AAI++ G+ F C
Sbjct: 379 LLSQAEPAPVGRQTCGKRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYI------GDSF-C 431
Query: 1334 GGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFD-DD 1510
G L+ +CWV+SAAHCF V VVLG+ + + Q F +EKYI + + +
Sbjct: 432 AGSLVHTCWVVSAAHCFSNSPRRESVLVVLGQHFFNQTTDVTQTFGIEKYIPYPMYSVFN 491
Query: 1511 TYDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSE 1690
D+D+ L++LK CA S V+ +CLPE + P +C+++G+G + + YS
Sbjct: 492 PSDHDLVLIRLKKKGDRCAIRSQFVQPICLPEPSSPFPAGHKCQIAGWGHQDENVSGYSS 551
Query: 1691 RLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAG--DTRSGGDDANLHDACQGDSGG 1852
L+EA V L C+S ++ I+ +MLCAG D +S DACQGDSGG
Sbjct: 552 SLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKS--------DACQGDSGG 599
Score = 125 bits (313), Expect = 2e-28
Identities = 64/168 (38%), Positives = 77/168 (45%)
Frame = +2
Query: 428 CRDEKTQMIYQQHQSWLRPLLRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQA 607
C DE + W R + +VE C C GQ +C +C C NGGTC
Sbjct: 200 CFDETRYEHLEAGDRWAR--VSQGQVEQCECAGGQIRCEGTRHTACLSSPCLNGGTCHLI 257
Query: 608 VYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMP 787
V VC CP G GR C I C+ G YRG ST SG C+ WN+ L
Sbjct: 258 VATGTTVCSCPPGHAGRLCNIVPSQRCFVGNGTEYRGVASTAASGLSCLAWNSDLLYQEL 317
Query: 788 YNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPAC 931
+ A LGLG H YCRNPDKD +PWCY+ K ++C AC
Sbjct: 318 HVDSVGAAALLGLGPHAYCRNPDKDERPWCYVVKDSALSWEYCRLAAC 365
>ref|XP_861645.1| PREDICTED: hepatocyte growth factor activator isoform 2 [Canis
familiaris]
Length = 657
Score = 229 bits (583), Expect = 9e-60
Identities = 154/476 (32%), Positives = 221/476 (46%), Gaps = 45/476 (9%)
Frame = +2
Query: 560 SCSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYED---QGITYRGTWST 730
SC+ C NGG+C + C CP+ F GR C+ + C+++ + + W+
Sbjct: 164 SCASSPCLNGGSCSHTQDPGSYHCTCPMAFTGRNCDTEK---CFDETRYEHLEAGDRWAR 220
Query: 731 TESG----AECVNW--------NTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPW 874
G EC +T+ L+S NG + + G C P +
Sbjct: 221 VSQGQVEQCECAGGQIRCEGTRHTACLSSPCLNGGTCHLI-VATGT-TVCSCPPGHAGRL 278
Query: 875 CYIFKAEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIY 1054
C I +++ C+ G G +YRG S SG CL WNS +L +++
Sbjct: 279 CNIVPSQR-----------------CFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELH 321
Query: 1055 TAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQC------------- 1195
A LGLG H YCRNPD D +PWC+V+KD L+WEYC L C
Sbjct: 322 VDSVGAAALLGLGPHAYCRNPDKDERPWCYVVKDSALSWEYCRLAACESLARIPSLTTAV 381
Query: 1196 ------------VTCGLRQYKEP--QFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLC 1333
TCG R K + RI GG + SHPW AAI++ G+ F C
Sbjct: 382 LLSQAEPAPVGRQTCGKRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYI------GDSF-C 434
Query: 1334 GGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFD-DD 1510
G L+ +CWV+SAAHCF V VVLG+ + + Q F +EKYI + + +
Sbjct: 435 AGSLVHTCWVVSAAHCFSNSPRRESVLVVLGQHFFNQTTDVTQTFGIEKYIPYPMYSVFN 494
Query: 1511 TYDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSE 1690
D+D+ L++LK CA S V+ +CLPE + P +C+++G+G + + YS
Sbjct: 495 PSDHDLVLIRLKKKGDRCAIRSQFVQPICLPEPSSPFPAGHKCQIAGWGHQDENVSGYSS 554
Query: 1691 RLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAG--DTRSGGDDANLHDACQGDSGG 1852
L+EA V L C+S ++ I+ +MLCAG D +S DACQGDSGG
Sbjct: 555 SLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKS--------DACQGDSGG 602
Score = 125 bits (313), Expect = 2e-28
Identities = 64/168 (38%), Positives = 77/168 (45%)
Frame = +2
Query: 428 CRDEKTQMIYQQHQSWLRPLLRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQA 607
C DE + W R + +VE C C GQ +C +C C NGGTC
Sbjct: 203 CFDETRYEHLEAGDRWAR--VSQGQVEQCECAGGQIRCEGTRHTACLSSPCLNGGTCHLI 260
Query: 608 VYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMP 787
V VC CP G GR C I C+ G YRG ST SG C+ WN+ L
Sbjct: 261 VATGTTVCSCPPGHAGRLCNIVPSQRCFVGNGTEYRGVASTAASGLSCLAWNSDLLYQEL 320
Query: 788 YNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPAC 931
+ A LGLG H YCRNPDKD +PWCY+ K ++C AC
Sbjct: 321 HVDSVGAAALLGLGPHAYCRNPDKDERPWCYVVKDSALSWEYCRLAAC 368
>ref|NP_001026985.1| HGF activator [Canis familiaris]
Length = 654
Score = 229 bits (583), Expect = 9e-60
Identities = 154/476 (32%), Positives = 221/476 (46%), Gaps = 45/476 (9%)
Frame = +2
Query: 560 SCSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYED---QGITYRGTWST 730
SC+ C NGG+C + C CP+ F GR C+ + C+++ + + W+
Sbjct: 161 SCASSPCLNGGSCSHTQDPGSYHCTCPMAFTGRNCDTEK---CFDETRYEHLEAGDRWAR 217
Query: 731 TESG----AECVNW--------NTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPW 874
G EC +T+ L+S NG + + G C P +
Sbjct: 218 VSQGQVEQCECAGGQIRCEGTRHTACLSSPCLNGGTCHLI-VATGT-TVCSCPPGHAGRL 275
Query: 875 CYIFKAEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIY 1054
C I +++ C+ G G +YRG S SG CL WNS +L +++
Sbjct: 276 CNIVPSQR-----------------CFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELH 318
Query: 1055 TAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQC------------- 1195
A LGLG H YCRNPD D +PWC+V+KD L+WEYC L C
Sbjct: 319 VDSVGAAALLGLGPHAYCRNPDKDERPWCYVVKDSALSWEYCRLAACESLARIPSLTTAV 378
Query: 1196 ------------VTCGLRQYKEP--QFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLC 1333
TCG R K + RI GG + SHPW AAI++ G+ F C
Sbjct: 379 LLSQAEPAPVGRQTCGKRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYI------GDSF-C 431
Query: 1334 GGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFD-DD 1510
G L+ +CWV+SAAHCF V VVLG+ + + Q F +EKYI + + +
Sbjct: 432 AGSLVHTCWVVSAAHCFSNSPRRESVLVVLGQHFFNQTTDVTQTFGIEKYIPYPMYSVFN 491
Query: 1511 TYDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSE 1690
D+D+ L++LK CA S V+ +CLPE + P +C+++G+G + + YS
Sbjct: 492 PSDHDLVLIRLKKKGDRCAIRSQFVQPICLPEPSSPFPAGHKCQIAGWGHQDENVSGYSS 551
Query: 1691 RLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAG--DTRSGGDDANLHDACQGDSGG 1852
L+EA V L C+S ++ I+ +MLCAG D +S DACQGDSGG
Sbjct: 552 SLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKS--------DACQGDSGG 599
Score = 125 bits (313), Expect = 2e-28
Identities = 64/168 (38%), Positives = 77/168 (45%)
Frame = +2
Query: 428 CRDEKTQMIYQQHQSWLRPLLRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQA 607
C DE + W R + +VE C C GQ +C +C C NGGTC
Sbjct: 200 CFDETRYEHLEAGDRWAR--VSQGQVEQCECAGGQIRCEGTRHTACLSSPCLNGGTCHLI 257
Query: 608 VYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMP 787
V VC CP G GR C I C+ G YRG ST SG C+ WN+ L
Sbjct: 258 VATGTTVCSCPPGHAGRLCNIVPSQRCFVGNGTEYRGVASTAASGLSCLAWNSDLLYQEL 317
Query: 788 YNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPAC 931
+ A LGLG H YCRNPDKD +PWCY+ K ++C AC
Sbjct: 318 HVDSVGAAALLGLGPHAYCRNPDKDERPWCYVVKDSALSWEYCRLAAC 365
>ref|XP_535016.2| PREDICTED: similar to hyaluronan binding protein 2 [Canis familiaris]
Length = 565
Score = 227 bits (579), Expect = 3e-59
Identities = 160/463 (34%), Positives = 223/463 (48%), Gaps = 33/463 (7%)
Frame = +2
Query: 563 CSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESG 742
C C +GG CL V +F C CPV F G +C+ + + C E+ RG T+S
Sbjct: 83 CQSNPCEHGGDCL--VNGENFTCSCPVPFSGNRCQ-NVQNKCKENP--CDRGECLITQSP 137
Query: 743 A--ECVNWNTSGLASMPYNGRRPDAVK-LGLGNHNYCRNPDKDSKPWCYIFKAEKYI--- 904
C PY G PD + + + N C+N S+ + K+
Sbjct: 138 PYYHCA-------CRHPYKG--PDCSRAVPVCRPNPCQNGGTCSRQR----RRSKFTCTC 184
Query: 905 PDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTL 1084
PD C ++CY G G YRG S T++ CL WNS +L+ + Y + +A+
Sbjct: 185 PDQFKGKFCEIGPDDCYVGDGYSYRGKVSKTVNQHSCLYWNSHLLLHENYNIFMEDAEAH 244
Query: 1085 GLGKHNYCRNPDGDTQPWCHVLKDH-KLTWEYCDLPQCV--------------------- 1198
G+G+HN+CRNPDGD +PWC + ++ KL WEYCD+ C
Sbjct: 245 GIGEHNFCRNPDGDKKPWCFIKANNAKLKWEYCDVSACSALDIADPEGSLTEPLTKLPGF 304
Query: 1199 -TCGLRQYKEPQFRIKGGLYADITSHPWQAAI--FVKNRRSPGERFLCGGILISSCWVLS 1369
+CG + + RI GG + HPWQA++ + S + CGG LI CWVL+
Sbjct: 305 DSCGRTEMTKKVKRIYGGFKSTAGKHPWQASLQTSLPLTVSMPQGHFCGGALIHPCWVLT 364
Query: 1370 AAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFD--DDTYDNDIALLQL 1543
AAHC H+ VVLG EQ F VEK + ++ ++ NDIALL+L
Sbjct: 365 AAHC--TNIKARHLTVVLGDQDLKKTEFHEQRFGVEKIFKYSLYNEREEIPHNDIALLKL 422
Query: 1544 KSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLYP 1723
K CA ES V+TVCLP N P TEC +SG+G E S +L +A VRL
Sbjct: 423 KPVDGHCALESKYVKTVCLP--NSAFPSGTECHISGWGVTETGEG--SRQLLDAKVRLIA 478
Query: 1724 SSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
++ C S+ L++ I M+CAG+ + G D+CQGDSGG
Sbjct: 479 NTLCNSRQLYDHMIGDSMICAGNLQKPG-----QDSCQGDSGG 516
>ref|XP_536394.2| PREDICTED: similar to urokinase plasminogen activator preproprotein
[Canis familiaris]
Length = 543
Score = 219 bits (558), Expect = 7e-57
Identities = 123/317 (38%), Positives = 166/317 (52%), Gaps = 16/317 (5%)
Frame = +2
Query: 950 CYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDT 1129
CY G G YRG + G CL WNS ++ K Y A +A LGLGKHNYCRNPD
Sbjct: 182 CYEGNGHSYRGKANTNTRGRPCLAWNSAAVLLKQYHALRPDALQLGLGKHNYCRNPDHQR 241
Query: 1130 QPWCHVLKDHKLTWEYCDLPQC--------------VTCGLRQYKEPQFRIKGGLYADIT 1267
+PWC+V + C + C CG + + P+F+I GG + I
Sbjct: 242 KPWCYVQVGLMQLVQECTVQHCSFEKNPHSPPEKAEFQCGQKALR-PRFKIIGGEFTTIE 300
Query: 1268 SHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVP 1447
+ PW AAI+ K+ R + CGG LIS CWV+SA HCF V LGR+ R+
Sbjct: 301 NQPWFAAIYRKH-RGGSVTYQCGGSLISPCWVVSATHCFINSQKKDDYIVYLGRSKRISK 359
Query: 1448 GEEEQAFEVEKYIVHKEFDDDT--YDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQL 1621
E FEVEK I+H+++ D+ + NDIALL+++SD CAQ S +++T+CLP +
Sbjct: 360 TFGEMKFEVEKLILHEDYSADSLAHHNDIALLKIRSDEGQCAQPSRSIQTICLPPSRGDA 419
Query: 1622 PDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRS 1801
CE+SG+GK ++ Y E+LK V+L C H + +T MLCA D
Sbjct: 420 HFGASCEISGFGKENSTDYLYPEQLKMTVVKLVSHQECQQPHYYGSEVTDQMLCAADPEW 479
Query: 1802 GGDDANLHDACQGDSGG 1852
D+CQGDSGG
Sbjct: 480 E------TDSCQGDSGG 490
Score = 134 bits (338), Expect = 2e-31
Identities = 61/132 (46%), Positives = 76/132 (57%), Gaps = 1/132 (0%)
Frame = +2
Query: 551 PVKSCSEPRCFNGGTCLQAVYFSDFV-CQCPVGFIGRQCEIDARATCYEDQGITYRGTWS 727
PV S S C NGGTC+ YFS+ C CP F G CEID TCYE G +YRG +
Sbjct: 136 PVSSASNCSCLNGGTCVSYKYFSNIQRCNCPKKFQGEHCEIDTSKTCYEGNGHSYRGKAN 195
Query: 728 TTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIP 907
T G C+ WN++ + Y+ RPDA++LGLG HNYCRNPD KPWCY+ +
Sbjct: 196 TNTRGRPCLAWNSAAVLLKQYHALRPDALQLGLGKHNYCRNPDHQRKPWCYVQVGLMQLV 255
Query: 908 DFCSTPACTKEK 943
C+ C+ EK
Sbjct: 256 QECTVQHCSFEK 267
>ref|XP_533468.2| PREDICTED: similar to Plasminogen precursor [Canis familiaris]
Length = 812
Score = 192 bits (489), Expect = 7e-49
Identities = 142/416 (34%), Positives = 196/416 (47%), Gaps = 27/416 (6%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT STT +G +C +W S + + + GL NYCRNPD D
Sbjct: 379 CYHGNGQSYRGTSSTTITGRKCQSW--SSMTPHRHEKTPEHFPEAGL-TMNYCRNPDADK 435
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK--------------------EECYTGKGLDYRGT 985
PWCY +FC+ C + +C G G YRG
Sbjct: 436 SPWCYTTDPSVRW-EFCNLRKCLDPEASATNSPAVPQVPSGQEPSASDCMFGNGKGYRGK 494
Query: 986 RSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ-PWCHVLKDHK 1162
++ T+ G C W + +N Q GL K NYCRNPDGD PWC+ + K
Sbjct: 495 KATTVMGIPCQEWAAQEPHRHSIFTPETNPQA-GLEK-NYCRNPDGDVNGPWCYTMNQRK 552
Query: 1163 LTWEYCDLPQCVT----CGLRQY--KEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGER 1324
L ++YCD+PQCV+ CG Q K+ R+ GG A+ S PWQ ++ R G+
Sbjct: 553 L-FDYCDVPQCVSTSFDCGKPQVEPKKCPGRVVGGCVANPHSWPWQISL----RTRYGKH 607
Query: 1325 FLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFD 1504
F CGG LIS WVL+AAHC + P +V+LG E +V++ V+K F
Sbjct: 608 F-CGGTLISPEWVLTAAHCLERSSRPASYKVILG-----AHKEVNLESDVQEIEVYKLFL 661
Query: 1505 DDTYDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFY 1684
+ T DIALL+L S ++ ++ V CLP N + D T C ++G+G E +
Sbjct: 662 EPT-RADIALLKLSSPAVITSK----VIPACLPPPNYVVADRTLCYITGWG--ETQGTYG 714
Query: 1685 SERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
+ LKEA + + + C N + LCAG+ G D+CQGDSGG
Sbjct: 715 AGLLKEAQLPVIENKVCNRYEYLNGRVKSTELCAGNLAGG------TDSCQGDSGG 764
Score = 117 bits (294), Expect = 3e-26
Identities = 65/173 (37%), Positives = 85/173 (49%), Gaps = 1/173 (0%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
C G TYRGT + T++ C W+ + Y P+ L NYCRNPD D
Sbjct: 103 CKTGNGKTYRGTMAKTKNDVACQKWSDNSPHKPNYT---PEKHPLEGLEENYCRNPDNDE 159
Query: 866 K-PWCYIFKAEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLM 1042
PWCY + D+C+ P C +EEC G +Y G S T SG C WNS
Sbjct: 160 NGPWCYTTNPDVRF-DYCNIPEC---EEECMHCSGENYEGKISKTKSGLECQAWNSQTPH 215
Query: 1043 GKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVT 1201
Y ++ L K NYCRNPDG+ +PWC + +K WE+CD+P+C T
Sbjct: 216 AHGYIPSKFPSKNL---KMNYCRNPDGEPRPWCFTMDPNK-RWEFCDIPRCTT 264
Score = 114 bits (284), Expect = 4e-25
Identities = 64/185 (34%), Positives = 88/185 (47%), Gaps = 7/185 (3%)
Frame = +2
Query: 662 CEI-DARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHN 838
C I + C G Y G S T+SG EC WN+ + Y + + L + N
Sbjct: 176 CNIPECEEECMHCSGENYEGKISKTKSGLECQAWNSQTPHAHGYIPSKFPSKNLKM---N 232
Query: 839 YCRNPDKDSKPWCYIFKAEKYIPDFCSTPACTKEKE------ECYTGKGLDYRGTRSLTM 1000
YCRNPD + +PWC+ K +FC P CT +C G+G YRG S+T+
Sbjct: 233 YCRNPDGEPRPWCFTMDPNKRW-EFCDIPRCTTPPPPSGPTYQCLKGRGESYRGKVSVTV 291
Query: 1001 SGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYC 1180
SG C W+ T N + L NYCRNPDG+T PWC+ + ++ WE+C
Sbjct: 292 SGHTCQHWSEQTPHKHNRTPENFPCKNL---DENYCRNPDGETAPWCYT-TNSEVRWEHC 347
Query: 1181 DLPQC 1195
+P C
Sbjct: 348 QIPSC 352
Score = 110 bits (274), Expect = 6e-24
Identities = 64/192 (33%), Positives = 91/192 (47%), Gaps = 21/192 (10%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPY-NGRRPDAVKLGLGNHNYCRNPDKD 862
C + +G +YRG S T SG C +W+ P+ + R P+ + NYCRNPD +
Sbjct: 275 CLKGRGESYRGKVSVTVSGHTCQHWSEQ----TPHKHNRTPENFPCKNLDENYCRNPDGE 330
Query: 863 SKPWCYIFKAEKYIPDFCSTPAC--------------------TKEKEECYTGKGLDYRG 982
+ PWCY +E + C P+C T +ECY G G YRG
Sbjct: 331 TAPWCYTTNSEVRW-EHCQIPSCESSPITTEYLDAPASVPPEQTPVVQECYHGNGQSYRG 389
Query: 983 TRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHK 1162
T S T++G C W+S+ T + L + NYCRNPD D PWC+ D
Sbjct: 390 TSSTTITGRKCQSWSSMTPHRHEKTPEHFPEAGLTM---NYCRNPDADKSPWCYT-TDPS 445
Query: 1163 LTWEYCDLPQCV 1198
+ WE+C+L +C+
Sbjct: 446 VRWEFCNLRKCL 457
Score = 60.1 bits (144), Expect = 7e-09
Identities = 35/107 (32%), Positives = 51/107 (47%), Gaps = 5/107 (4%)
Frame = +2
Query: 947 ECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGD 1126
EC TG G YRGT + T + C W+ YT + L + NYCRNPD D
Sbjct: 102 ECKTGNGKTYRGTMAKTKNDVACQKWSDNSPHKPNYTPEKHPLEGL---EENYCRNPDND 158
Query: 1127 TQ-PWCHVLKDHKLTWEYCDLP----QCVTCGLRQYKEPQFRIKGGL 1252
PWC+ + + ++YC++P +C+ C Y+ + K GL
Sbjct: 159 ENGPWCYT-TNPDVRFDYCNIPECEEECMHCSGENYEGKISKTKSGL 204
>ref|XP_546206.2| PREDICTED: similar to Coagulation factor XII precursor (Hageman
factor) (HAF) [Canis familiaris]
Length = 611
Score = 184 bits (467), Expect = 3e-46
Identities = 152/497 (30%), Positives = 208/497 (41%), Gaps = 72/497 (14%)
Frame = +2
Query: 578 CFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITY---RGTWSTTESGAE 748
C GGTC+ C CP F G+ C+ R C+E Q + + + W E
Sbjct: 104 CQKGGTCVNMPDGPH--CICPEHFTGKHCQ---REKCFEPQLLQFFHEKEIWHRLEP--- 155
Query: 749 CVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEK---------Y 901
+G+A G PD + + NP + F+AE Y
Sbjct: 156 ------AGVAKCECRG--PDVHCKLVASQGCHTNPCLNGGT---CFQAETHRLCRCPTGY 204
Query: 902 IPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQT 1081
FC + CY G+GLDYRG +SGA C W S ++ A +
Sbjct: 205 AGRFCDVDTGAR----CYHGRGLDYRGAADAALSGARCQRWASEASYQEVPA---EQALS 257
Query: 1082 LGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDL------------------------- 1186
GLG H +CRNPD DT+PWC V +L+WEYC L
Sbjct: 258 WGLGNHAFCRNPDNDTRPWCFVRSGDRLSWEYCRLARCQAPGLAIPQILPPTQVPSGRPT 317
Query: 1187 -----------PQCVT-----------------CG--LRQYKEPQFRIKGGLYADITSHP 1276
PQ T CG LR+ R+ GGL A +HP
Sbjct: 318 LPVPSPSALQKPQPPTPASSATREQPAAVPSSRCGQRLRKRLSSLSRVVGGLVALPGAHP 377
Query: 1277 WQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEE 1456
+ AA++ ++ C G LI+SCWVL+AAHC Q+R P + VVLG+ E+
Sbjct: 378 YIAALYWRHS-------FCAGSLIASCWVLTAAHCLQDRPAPGELTVVLGQDRHNRSCEQ 430
Query: 1457 EQAFEVEKYIVHKEFDDDTYDNDIALLQLKSDS-LTCAQESDAVRTVCLPEANLQ----L 1621
Q V Y +H+ F TY +D+ALL+L+ + CA S V+ VCLP +
Sbjct: 431 CQTLAVRAYRLHESFSPVTYQHDLALLRLQETADGRCALPSPFVQPVCLPSGAARPAEAQ 490
Query: 1622 PDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRS 1801
+ CE++G+G + YS L+EA V L P C++ + + MLCAG
Sbjct: 491 AEAALCEVAGWGHLFEGAGEYSSFLQEAQVPLIPPQRCSAPEVHGASFIPGMLCAGFLEG 550
Query: 1802 GGDDANLHDACQGDSGG 1852
G DACQGDSGG
Sbjct: 551 G------TDACQGDSGG 561
Score = 118 bits (295), Expect = 2e-26
Identities = 56/169 (33%), Positives = 83/169 (49%), Gaps = 1/169 (0%)
Frame = +2
Query: 428 CRDEKTQMIYQQHQSWLRPLLRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQA 607
C + + + + + W R L V C C C V + C C NGGTC QA
Sbjct: 135 CFEPQLLQFFHEKEIWHR--LEPAGVAKCECRGPDVHCKLVASQGCHTNPCLNGGTCFQA 192
Query: 608 VYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESGAECVNW-NTSGLASM 784
+ +C+CP G+ GR C++D A CY +G+ YRG SGA C W + + +
Sbjct: 193 E--THRLCRCPTGYAGRFCDVDTGARCYHGRGLDYRGAADAALSGARCQRWASEASYQEV 250
Query: 785 PYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPAC 931
P A+ GLGNH +CRNPD D++PWC++ ++ ++C C
Sbjct: 251 P----AEQALSWGLGNHAFCRNPDNDTRPWCFVRSGDRLSWEYCRLARC 295
>ref|NP_001002964.1| hepatocyte growth factor [Canis familiaris]
Length = 730
Score = 141 bits (355), Expect = 2e-33
Identities = 107/410 (26%), Positives = 171/410 (41%), Gaps = 21/410 (5%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPY-NGRRPDAVKLGLGNHNYCRNPDKD 862
C + QG YRGT +T +G C W++ P+ + P+ K NYCRNPD
Sbjct: 305 CIQGQGEGYRGTINTIWNGVPCQRWDSQ----YPHQHDITPENFKCKDLRENYCRNPDGA 360
Query: 863 SKPWCYIFKAEKYIPDFCSTPAC-TKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVL 1039
PWC+ + P C ++CY G G +Y G S T SG C W +
Sbjct: 361 ESPWCFTTDPNIRVGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWEKNME 420
Query: 1040 MGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ-PWCHVLKDHKLTWEYCDLPQC------- 1195
+ W +A L NYCRNPD D PWC+ + + W+YC + +C
Sbjct: 421 DLHRHIFWEPDASKLN---KNYCRNPDDDAHGPWCYT-GNPLIPWDYCPIFRCEGDTTPT 476
Query: 1196 --------VTCGLRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILIS 1351
++C K Q R+ G+ T+ W ++ +N+ +CGG LI
Sbjct: 477 IVNLDHPVISCA----KTKQLRVVNGIPTR-TNVGWMVSLKYRNKH------ICGGSLIK 525
Query: 1352 SCWVLSAAHCFQER---FPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDN 1522
W+L+A CF R + + + + + +Q V + + E +
Sbjct: 526 ESWILTARQCFPSRNRDLKDYEAWLGIHDVHGKGDEKRKQVLNVSQLVYGPE------GS 579
Query: 1523 DIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKE 1702
D+ LL+L ++ D V T+ LP +P+ T C + G+G S + L+
Sbjct: 580 DLVLLKLARPAIL----DDFVSTIDLPNYGCTIPEKTTCSVYGWG--YTGSINFDGLLRV 633
Query: 1703 AHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
AH+ + + C+ H T+ + +CA G + + C+GD GG
Sbjct: 634 AHLYIMGNEKCSQYHQGKVTLNESEICA------GAENIVSGPCEGDYGG 677
Score = 92.8 bits (229), Expect = 1e-18
Identities = 59/175 (33%), Positives = 81/175 (46%), Gaps = 5/175 (2%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTS---GLASMPYNGRRPDAVKLGLGNHNYCRNP- 853
C +G +Y+GT S T+SG +C WN+ + +P + R D NYCRNP
Sbjct: 128 CIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDL------QENYCRNPR 181
Query: 854 DKDSKPWCYIFKAE-KYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNS 1030
++ PWC+ E +Y + C P C++ EC T G YRG T SG C W+
Sbjct: 182 GEEGGPWCFTSNPEVRY--EVCDIPQCSEV--ECMTCNGESYRGPMDHTESGKICQRWDH 237
Query: 1031 LVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQC 1195
+ + NYCRNPDG +PWC+ L D WEYC + C
Sbjct: 238 QTPHRHKFLPERYPDKGFD---DNYCRNPDGKPRPWCYTL-DPDTPWEYCAIKMC 288
Score = 89.7 bits (221), Expect = 9e-18
Identities = 72/227 (31%), Positives = 92/227 (40%), Gaps = 16/227 (7%)
Frame = +2
Query: 563 CSEPRCFNGG----TCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWST 730
C PR GG T V + VC P QC + C G +YRG
Sbjct: 177 CRNPRGEEGGPWCFTSNPEVRYE--VCDIP------QC---SEVECMTCNGESYRGPMDH 225
Query: 731 TESGAECVNWNTSGLASMPYNGRR-PDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIP 907
TESG C W+ + R PD G + NYCRNPD +PWCY +
Sbjct: 226 TESGKICQRWDHQTPHRHKFLPERYPDK---GFDD-NYCRNPDGKPRPWCYTLDPDTPW- 280
Query: 908 DFCSTPACTK----------EKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT 1057
++C+ C E EC G+G YRGT + +G C W+S T
Sbjct: 281 EYCAIKMCAHSTMNDTDVPMETTECIQGQGEGYRGTINTIWNGVPCQRWDSQYPHQHDIT 340
Query: 1058 AWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYC-DLPQC 1195
N + L + NYCRNPDG PWC D + YC +P+C
Sbjct: 341 PENFKCKDL---RENYCRNPDGAESPWCFT-TDPNIRVGYCSQIPKC 383
Score = 70.9 bits (172), Expect = 4e-12
Identities = 38/106 (35%), Positives = 55/106 (51%), Gaps = 6/106 (5%)
Frame = +2
Query: 950 CYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDT 1129
C GKG Y+GT S+T SG C PWNS++ + + + L + NYCRNP G+
Sbjct: 128 CIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDL---QENYCRNPRGEE 184
Query: 1130 -QPWCHVLKDHKLTWEYCDLPQ-----CVTCGLRQYKEPQFRIKGG 1249
PWC + ++ +E CD+PQ C+TC Y+ P + G
Sbjct: 185 GGPWCFT-SNPEVRYEVCDIPQCSEVECMTCNGESYRGPMDHTESG 229
Score = 59.3 bits (142), Expect = 1e-08
Identities = 35/93 (37%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +2
Query: 659 QCEIDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHN 838
+C++ + CY G Y G S T SG C W + + PDA KL N N
Sbjct: 382 KCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWEKNMEDLHRHIFWEPDASKL---NKN 438
Query: 839 YCRNPDKDSK-PWCYIFKAEKYIP-DFCSTPAC 931
YCRNPD D+ PWCY IP D+C C
Sbjct: 439 YCRNPDDDAHGPWCY--TGNPLIPWDYCPIFRC 469
>ref|XP_541884.2| PREDICTED: similar to macrophage stimulating 1 (hepatocyte growth
factor-like) [Canis familiaris]
Length = 712
Score = 132 bits (331), Expect = 1e-30
Identities = 117/417 (28%), Positives = 177/417 (42%), Gaps = 28/417 (6%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGR-RPDAVKLGLGNHNYCRNPDKD 862
C+ +G YRGT +TT +G C W+ A P+ R P+ N+CRNPD
Sbjct: 284 CFRGKGEGYRGTANTTAAGVPCQRWD----AQKPHQHRFAPEKYACKDLRENFCRNPDGS 339
Query: 863 SKPWCYIFKAEKYIPDFCSTPACTKE--KEECYTGKGLDYRGTRSLTMSGAFCLPWNSLV 1036
PWC+ + + P C + E+CY G G YRG+ S T G C W++ +
Sbjct: 340 EAPWCFTSRPGMRVAFCYQIPRCADDVRPEDCYNGVGERYRGSVSRTRKGVPCQHWSAEM 399
Query: 1037 LMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ-PWCHVLKDHKLTWEYCDLPQC------ 1195
+TA ++ L + N+CRNPD D+ PWC+ D ++YC L +C
Sbjct: 400 PHKPQFTAISAPDAHL---EENFCRNPDRDSHGPWCYT-TDPGTPFDYCALRRCDDDQPP 455
Query: 1196 -----------VTCGLR----QYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFL 1330
CG R + + R+ GG + PW ++ R G+ F
Sbjct: 456 SILEPPDQVVFEKCGKRVTRLDQQRSKLRVVGG---QPGNSPWTVSL----RNRQGQHF- 507
Query: 1331 CGGILISSCWVLSAAHCFQE-RFPPHHVRVVLGRTYR-LVPGEEE-QAFEVEKYIVHKEF 1501
CGG L+ WVL+A CF P V LG ++ PGE Q V K +
Sbjct: 508 CGGSLVKEQWVLTARQCFSSCHVPLMGYEVWLGTLFQNPQPGEPGLQQIPVAKMVCGPS- 566
Query: 1502 DDDTYDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPF 1681
+ + LL+L+ +T Q V +CLP +P T+CE++G+G E
Sbjct: 567 -----GSQLVLLKLER-PVTLNQR---VALICLPPERYVVPPGTKCEIAGWG--ETKGTG 615
Query: 1682 YSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
++ L A + + + C KH I ++ +C + AC+GD GG
Sbjct: 616 NNKVLNVASLNVISNQECNIKH--RGRIRENEMCTEGLLAP------VGACEGDYGG 664
Score = 95.5 bits (236), Expect = 2e-19
Identities = 72/244 (29%), Positives = 105/244 (43%), Gaps = 19/244 (7%)
Frame = +2
Query: 683 TCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKD 862
TC D G+ YRGT + T G C +W+ P + + ++ GL N+CRNPD+D
Sbjct: 110 TCITDNGVKYRGTVAITTGGLPCQHWSHR----FPNDHKYTPTLRNGL-EENFCRNPDRD 164
Query: 863 -SKPWCYIFKAEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVL 1039
PWCY C +C + C G DYRG T SG C W+
Sbjct: 165 PGGPWCYTTDPAVRFQS-CGIKSC--REAACVWCNGEDYRGAVDRTQSGRECQRWD---- 217
Query: 1040 MGKIYTAWNSNAQTLGLGKH-------NYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCV 1198
+ +A GK NYCRNPDG +PWC+ D ++ E+CDL +C
Sbjct: 218 ------LQHPHAHPFEPGKFLDKDLDDNYCRNPDGSERPWCYT-TDPQVEREFCDLTRCG 270
Query: 1199 TCGLRQYKEPQ---FRIKGGLY--------ADITSHPWQAAIFVKNRRSPGERFLCGGIL 1345
+ +++ FR KG Y A + W A ++R +P E++ C +
Sbjct: 271 SEAQPRHESTTLNCFRGKGEGYRGTANTTAAGVPCQRWDAQKPHQHRFAP-EKYACKDLR 329
Query: 1346 ISSC 1357
+ C
Sbjct: 330 ENFC 333
Score = 90.5 bits (223), Expect = 5e-18
Identities = 54/180 (30%), Positives = 76/180 (42%), Gaps = 8/180 (4%)
Frame = +2
Query: 680 ATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDK 859
A C G YRG T+SG EC W+ + P+ + L + NYCRNPD
Sbjct: 190 AACVWCNGEDYRGAVDRTQSGRECQRWDLQHPHAHPFEPGKFLDKDL---DDNYCRNPDG 246
Query: 860 DSKPWCYIFKAEKYIPDFCSTPACTKEKE--------ECYTGKGLDYRGTRSLTMSGAFC 1015
+PWCY + +FC C E + C+ GKG YRGT + T +G C
Sbjct: 247 SERPWCYTTDPQVE-REFCDLTRCGSEAQPRHESTTLNCFRGKGEGYRGTANTTAAGVPC 305
Query: 1016 LPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQC 1195
W++ + + L + N+CRNPDG PWC + +P+C
Sbjct: 306 QRWDAQKPHQHRFAPEKYACKDL---RENFCRNPDGSEAPWCFTSRPGMRVAFCYQIPRC 362
Database: RefSeqCP
Posted date: Aug 1, 2006 9:25 PM
Number of letters in database: 19,266,565
Number of sequences in database: 33,732
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,361,943
Number of Sequences: 33732
Number of extensions: 2940274
Number of successful extensions: 14696
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 8648
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 14053
length of database: 19,266,565
effective HSP length: 109
effective length of database: 15,589,777
effective search space used: 7919606716
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqHP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-007176
(1854 letters)
Database: RefSeqHP
39,411 sequences; 17,774,539 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_000921.1| plasminogen activator, tissue type isoform 1 pr... 912 0.0
Alignment gi|NP_127509.1| plasminogen activator, tissue type isoform 3 pr... 801 0.0
Alignment gi|NP_000922.2| plasminogen activator, tissue type isoform 2 pr... 450 e-126
Alignment gi|NP_001519.1| HGF activator preproprotein [Homo sapiens] 228 1e-59
Alignment gi|NP_004123.1| hyaluronan binding protein 2 [Homo sapiens] 225 1e-58
Alignment gi|NP_002649.1| urokinase plasminogen activator preproprotein [... 221 2e-57
Alignment gi|NP_000292.1| plasminogen [Homo sapiens] 196 7e-50
Alignment gi|NP_005568.1| lipoprotein, Lp(a) [Homo sapiens] 173 5e-43
Alignment gi|XP_946885.1| PREDICTED: similar to Apolipoprotein(a) precurs... 151 2e-36
Alignment gi|XP_931416.1| PREDICTED: similar to Apolipoprotein(a) precurs... 151 2e-36
>ref|NP_000921.1| plasminogen activator, tissue type isoform 1 preproprotein [Homo
sapiens]
Length = 562
Score = 912 bits (2357), Expect = 0.0
Identities = 409/515 (79%), Positives = 448/515 (86%)
Frame = +2
Query: 308 MYALKRELWCVLLLCGAICTSPSQETHXXXXXXXXXXXVTCRDEKTQMIYQQHQSWLRPL 487
M A+KR L CVLLLCGA+ SPSQE H V CRDEKTQMIYQQHQSWLRP+
Sbjct: 1 MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDEKTQMIYQQHQSWLRPV 60
Query: 488 LRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCE 667
LR NRVE+CWCN G+ QCHSVPVKSCSEPRCFNGGTC QA+YFSDFVCQCP GF G+ CE
Sbjct: 61 LRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCE 120
Query: 668 IDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCR 847
ID RATCYEDQGI+YRGTWST ESGAEC NWN+S LA PY+GRRPDA++LGLGNHNYCR
Sbjct: 121 IDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCR 180
Query: 848 NPDKDSKPWCYIFKAEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWN 1027
NPD+DSKPWCY+FKA KY +FCSTPAC++ +CY G G YRGT SLT SGA CLPWN
Sbjct: 181 NPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWN 240
Query: 1028 SLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVTCG 1207
S++L+GK+YTA N +AQ LGLGKHNYCRNPDGD +PWCHVLK+ +LTWEYCD+P C TCG
Sbjct: 241 SMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCG 300
Query: 1208 LRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQ 1387
LRQY +PQFRIKGGL+ADI SHPWQAAIF K+RRSPGERFLCGGILISSCW+LSAAHCFQ
Sbjct: 301 LRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQ 360
Query: 1388 ERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDNDIALLQLKSDSLTCA 1567
ERFPPHH+ V+LGRTYR+VPGEEEQ FEVEKYIVHKEFDDDTYDNDIALLQLKSDS CA
Sbjct: 361 ERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCA 420
Query: 1568 QESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSSCCTSKH 1747
QES VRTVCLP A+LQLPDWTECELSGYGKHEA SPFYSERLKEAHVRLYPSS CTS+H
Sbjct: 421 QESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQH 480
Query: 1748 LFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
L N+T+T +MLCAGDTRSGG ANLHDACQGDSGG
Sbjct: 481 LLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGG 515
>ref|NP_127509.1| plasminogen activator, tissue type isoform 3 precursor [Homo sapiens]
Length = 516
Score = 801 bits (2070), Expect = 0.0
Identities = 372/515 (72%), Positives = 409/515 (79%)
Frame = +2
Query: 308 MYALKRELWCVLLLCGAICTSPSQETHXXXXXXXXXXXVTCRDEKTQMIYQQHQSWLRPL 487
M A+KR L CVLLLCGA+ SPSQE H
Sbjct: 1 MDAMKRGLCCVLLLCGAVFVSPSQEIHARFR----------------------------- 31
Query: 488 LRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCE 667
RG R + CSEPRCFNGGTC QA+YFSDFVCQCP GF G+ CE
Sbjct: 32 -RGAR----------------SYQGCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCE 74
Query: 668 IDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCR 847
ID RATCYEDQGI+YRGTWST ESGAEC NWN+S LA PY+GRRPDA++LGLGNHNYCR
Sbjct: 75 IDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCR 134
Query: 848 NPDKDSKPWCYIFKAEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWN 1027
NPD+DSKPWCY+FKA KY +FCSTPAC++ +CY G G YRGT SLT SGA CLPWN
Sbjct: 135 NPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWN 194
Query: 1028 SLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVTCG 1207
S++L+GK+YTA N +AQ LGLGKHNYCRNPDGD +PWCHVLK+ +LTWEYCD+P C TCG
Sbjct: 195 SMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCG 254
Query: 1208 LRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQ 1387
LRQY +PQFRIKGGL+ADI SHPWQAAIF K+RRSPGERFLCGGILISSCW+LSAAHCFQ
Sbjct: 255 LRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQ 314
Query: 1388 ERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDNDIALLQLKSDSLTCA 1567
ERFPPHH+ V+LGRTYR+VPGEEEQ FEVEKYIVHKEFDDDTYDNDIALLQLKSDS CA
Sbjct: 315 ERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCA 374
Query: 1568 QESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSSCCTSKH 1747
QES VRTVCLP A+LQLPDWTECELSGYGKHEA SPFYSERLKEAHVRLYPSS CTS+H
Sbjct: 375 QESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQH 434
Query: 1748 LFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
L N+T+T +MLCAGDTRSGG ANLHDACQGDSGG
Sbjct: 435 LLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGG 469
>ref|NP_000922.2| plasminogen activator, tissue type isoform 2 precursor [Homo sapiens]
Length = 291
Score = 450 bits (1158), Expect = e-126
Identities = 199/276 (72%), Positives = 223/276 (80%)
Frame = +2
Query: 308 MYALKRELWCVLLLCGAICTSPSQETHXXXXXXXXXXXVTCRDEKTQMIYQQHQSWLRPL 487
M A+KR L CVLLLCGA+ SPSQE H V CRDEKTQMIYQQHQSWLRP+
Sbjct: 1 MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDEKTQMIYQQHQSWLRPV 60
Query: 488 LRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCE 667
LR NRVE+CWCN G+ QCHSVPVKSCSEPRCFNGGTC QA+YFSDFVCQCP GF G+ CE
Sbjct: 61 LRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCE 120
Query: 668 IDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCR 847
ID RATCYEDQGI+YRGTWST ESGAEC NWN+S LA PY+GRRPDA++LGLGNHNYCR
Sbjct: 121 IDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCR 180
Query: 848 NPDKDSKPWCYIFKAEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWN 1027
NPD+DSKPWCY+FKA KY +FCSTPAC++ +CY G G YRGT SLT SGA CLPWN
Sbjct: 181 NPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWN 240
Query: 1028 SLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQP 1135
S++L+GK+YTA N +AQ LGLGKHNYCR + P
Sbjct: 241 SMILIGKVYTAQNPSAQALGLGKHNYCRTGRSVSSP 276
Score = 95.1 bits (235), Expect = 2e-19
Identities = 42/82 (51%), Positives = 51/82 (62%)
Frame = +2
Query: 950 CYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDT 1129
CY +G+ YRGT S SGA C WNS L K Y+ +A LGLG HNYCRNPD D+
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDS 186
Query: 1130 QPWCHVLKDHKLTWEYCDLPQC 1195
+PWC+V K K + E+C P C
Sbjct: 187 KPWCYVFKAGKYSSEFCSTPAC 208
>ref|NP_001519.1| HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 228 bits (581), Expect = 1e-59
Identities = 154/472 (32%), Positives = 216/472 (45%), Gaps = 42/472 (8%)
Frame = +2
Query: 563 CSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYR---GTWSTT 733
C+ C NGG+C + C CP F G+ C + C+++ Y W+
Sbjct: 164 CASGPCLNGGSCSNTQDPQSYHCSCPRAFTGKDCGTEK---CFDETRYEYLEGGDRWARV 220
Query: 734 ESG----AECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKY 901
G EC T G R H C + + C++ A
Sbjct: 221 RQGHVEQCECFGGRTW------CEGTR----------HTACLSSPCLNGGTCHLIVATGT 264
Query: 902 I-----PDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWN 1066
P F + E C+ G G YRG S + SG CL WNS +L +++
Sbjct: 265 TVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSV 324
Query: 1067 SNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVT--------------- 1201
A LGLG H YCRNPD D +PWC+V+KD L+WEYC L C +
Sbjct: 325 GAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLP 384
Query: 1202 ---------CGLRQYKEPQF---RIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGIL 1345
CG R++K+ F RI GG + SHPW AAI++ G+ F C G L
Sbjct: 385 EPASPGRQACG-RRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYI------GDSF-CAGSL 436
Query: 1346 ISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFD-DDTYDN 1522
+ +CWV+SAAHCF P V VVLG+ + + Q F +EKYI + + + D+
Sbjct: 437 VHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDH 496
Query: 1523 DIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKE 1702
D+ L++LK CA S V+ +CLPE P +C+++G+G + + YS L+E
Sbjct: 497 DLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLRE 556
Query: 1703 AHVRLYPSSCCTSKHLFNKTITKHMLCAG--DTRSGGDDANLHDACQGDSGG 1852
A V L C+S ++ I+ +MLCAG D +S DACQGDSGG
Sbjct: 557 ALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKS--------DACQGDSGG 600
Score = 128 bits (321), Expect = 2e-29
Identities = 65/168 (38%), Positives = 79/168 (47%)
Frame = +2
Query: 428 CRDEKTQMIYQQHQSWLRPLLRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQA 607
C DE + W R +R VE C C G+T C +C C NGGTC
Sbjct: 202 CFDETRYEYLEGGDRWAR--VRQGHVEQCECFGGRTWCEGTRHTACLSSPCLNGGTCHLI 259
Query: 608 VYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMP 787
V VC CP GF GR C I+ C+ G YRG ST+ SG C+ WN+ L
Sbjct: 260 VATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQEL 319
Query: 788 YNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPAC 931
+ A LGLG H YCRNPD D +PWCY+ K ++C AC
Sbjct: 320 HVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEAC 367
>ref|NP_004123.1| hyaluronan binding protein 2 [Homo sapiens]
Length = 560
Score = 225 bits (573), Expect = 1e-58
Identities = 155/462 (33%), Positives = 221/462 (47%), Gaps = 32/462 (6%)
Frame = +2
Query: 563 CSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESG 742
C C +GG CL V+ S F C C F G +C+ + TC ++ RG T+S
Sbjct: 77 CQPNPCEHGGDCL--VHGSTFTCSCLAPFSGNKCQ-KVQNTCKDNP--CGRGQCLITQSP 131
Query: 743 ----AECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPD 910
C + T S RP+ + G C + SK C PD
Sbjct: 132 PYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGAT----CSRHKRRSKFTCAC-------PD 180
Query: 911 FCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGL 1090
C ++CY G G YRG + T++ CL WNS +L+ + Y + +A+T G+
Sbjct: 181 QFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGI 240
Query: 1091 GKHNYCRNPDGDTQPWCHV-LKDHKLTWEYCDLPQCV----------------------T 1201
G+HN+CRNPD D +PWC + + + K+ WEYCD+ C +
Sbjct: 241 GEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDS 300
Query: 1202 CGLRQYKEPQF-RIKGGLYADITSHPWQAAI--FVKNRRSPGERFLCGGILISSCWVLSA 1372
CG + E + RI GG + HPWQA++ + S + CGG LI CWVL+A
Sbjct: 301 CGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTA 360
Query: 1373 AHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFD--DDTYDNDIALLQLK 1546
AHC H++VVLG EQ+F VEK + ++ D+ NDIALL+LK
Sbjct: 361 AHCTD--IKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLK 418
Query: 1547 SDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLYPS 1726
CA ES V+TVCLP+ + P +EC +SG+G E S +L +A V+L +
Sbjct: 419 PVDGHCALESKYVKTVCLPDGS--FPSGSECHISGWGVTETGKG--SRQLLDAKVKLIAN 474
Query: 1727 SCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
+ C S+ L++ I M+CAG+ + G D CQGDSGG
Sbjct: 475 TLCNSRQLYDHMIDDSMICAGNLQKPG-----QDTCQGDSGG 511
Score = 100 bits (250), Expect = 3e-21
Identities = 56/146 (38%), Positives = 72/146 (49%), Gaps = 3/146 (2%)
Frame = +2
Query: 512 CWCNDGQT--QCHSVPVKSCSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARAT 685
C C T C V V C C NG TC + S F C CP F G+ CEI +
Sbjct: 136 CVCKHPYTGPSCSQV-VPVCRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGS-DD 193
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRG + T + C+ WN+ L YN DA G+G HN+CRNPD D
Sbjct: 194 CYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDADE 253
Query: 866 KPWCYI-FKAEKYIPDFCSTPACTKE 940
KPWC+I +K ++C AC+ +
Sbjct: 254 KPWCFIKVTNDKVKWEYCDVSACSAQ 279
>ref|NP_002649.1| urokinase plasminogen activator preproprotein [Homo sapiens]
Length = 431
Score = 221 bits (563), Expect = 2e-57
Identities = 124/321 (38%), Positives = 169/321 (52%), Gaps = 16/321 (4%)
Frame = +2
Query: 938 EKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNP 1117
+ + CY G G YRG S G CLPWNS ++ + Y A S+A LGLGKHNYCRNP
Sbjct: 66 KSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNP 125
Query: 1118 DGDTQPWCHVLKDHKLTWEYCDLPQCV--------------TCGLRQYKEPQFRIKGGLY 1255
D +PWC+V K + C + C CG + + P+F+I GG +
Sbjct: 126 DNRRRPWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLR-PRFKIIGGEF 184
Query: 1256 ADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTY 1435
I + PW AAI+ + R ++CGG LIS CWV+SA HCF + V LGR+
Sbjct: 185 TTIENQPWFAAIY-RRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSR 243
Query: 1436 RLVPGEEEQAFEVEKYIVHKEFDDDT--YDNDIALLQLKSDSLTCAQESDAVRTVCLPEA 1609
+ E FEVE I+HK++ DT + NDIALL+++S CAQ S ++T+CLP
Sbjct: 244 LNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSM 303
Query: 1610 NLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAG 1789
T CE++G+GK ++ Y E+LK V+L C H + +T MLCA
Sbjct: 304 YNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAA 363
Query: 1790 DTRSGGDDANLHDACQGDSGG 1852
D + D+CQGDSGG
Sbjct: 364 DPQW------KTDSCQGDSGG 378
Score = 126 bits (317), Expect = 5e-29
Identities = 61/141 (43%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
Frame = +2
Query: 527 GQTQCHSVPVKSCSEPRCFNGGTCLQAVYFSDFV-CQCPVGFIGRQCEIDARATCYEDQG 703
G + H VP S C NGGTC+ YFS+ C CP F G+ CEID TCYE G
Sbjct: 20 GSNELHQVP----SNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTCYEGNG 75
Query: 704 ITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYI 883
YRG ST G C+ WN++ + Y+ R DA++LGLG HNYCRNPD +PWCY+
Sbjct: 76 HFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYV 135
Query: 884 FKAEKYIPDFCSTPACTKEKE 946
K + C C K+
Sbjct: 136 QVGLKPLVQECMVHDCADGKK 156
>ref|NP_000292.1| plasminogen [Homo sapiens]
Length = 810
Score = 196 bits (497), Expect = 7e-50
Identities = 142/417 (34%), Positives = 193/417 (46%), Gaps = 28/417 (6%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT STT +G +C +W S + + + GL NYCRNPD D
Sbjct: 377 CYHGDGQSYRGTSSTTTTGKKCQSW--SSMTPHRHQKTPENYPNAGL-TMNYCRNPDADK 433
Query: 866 KPWCYIFKAEKYIP-DFCSTPAC--------------------TKEKEECYTGKGLDYRG 982
PWC F + + ++C+ C T +E+C G G YRG
Sbjct: 434 GPWC--FTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRG 491
Query: 983 TRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ-PWCHVLKDH 1159
R+ T++G C W + +N + GL K NYCRNPDGD PWC+
Sbjct: 492 KRATTVTGTPCQDWAAQEPHRHSIFTPETNPRA-GLEK-NYCRNPDGDVGGPWCYTTNPR 549
Query: 1160 KLTWEYCDLPQCVT----CGLRQY--KEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGE 1321
KL ++YCD+PQC CG Q K+ R+ GG A S PWQ ++ R G
Sbjct: 550 KL-YDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSL----RTRFGM 604
Query: 1322 RFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEF 1501
F CGG LIS WVL+AAHC ++ P +V+LG + Q EV + +
Sbjct: 605 HF-CGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFL---- 659
Query: 1502 DDDTYDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPF 1681
+ DIALL+L S ++ +D V CLP N + D TEC ++G+G E F
Sbjct: 660 --EPTRKDIALLKLSSPAVI----TDKVIPACLPSPNYVVADRTECFITGWG--ETQGTF 711
Query: 1682 YSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
+ LKEA + + + C N + LCAG G D+CQGDSGG
Sbjct: 712 GAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGG------TDSCQGDSGG 762
Score = 111 bits (278), Expect = 2e-24
Identities = 67/174 (38%), Positives = 84/174 (48%), Gaps = 2/174 (1%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLG-NHNYCRNPDKD 862
C G YRGT S T++G C W+++ P+ R A G NYCRNPD D
Sbjct: 103 CKTGNGKNYRGTMSKTKNGITCQKWSSTS----PHRPRFSPATHPSEGLEENYCRNPDND 158
Query: 863 SK-PWCYIFKAEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVL 1039
+ PWCY EK D+C C +EEC G +Y G S TMSG C W+S
Sbjct: 159 PQGPWCYTTDPEKRY-DYCDILEC---EEECMHCSGENYDGKISKTMSGLECQAWDSQSP 214
Query: 1040 MGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVT 1201
Y + L K NYCRNPD + +PWC +K WE CD+P+C T
Sbjct: 215 HAHGYIPSKFPNKNL---KKNYCRNPDRELRPWCFTTDPNK-RWELCDIPRCTT 264
Score = 108 bits (269), Expect = 2e-23
Identities = 63/185 (34%), Positives = 85/185 (45%), Gaps = 7/185 (3%)
Frame = +2
Query: 662 CEI-DARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHN 838
C+I + C G Y G S T SG EC W++ S +G P N
Sbjct: 176 CDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQ---SPHAHGYIPSKFPNKNLKKN 232
Query: 839 YCRNPDKDSKPWCYIFKAEKYIPDFCSTPACTKEKE------ECYTGKGLDYRGTRSLTM 1000
YCRNPD++ +PWC+ K + C P CT +C G G +YRG ++T+
Sbjct: 233 YCRNPDRELRPWCFTTDPNKRW-ELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTV 291
Query: 1001 SGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYC 1180
SG C W++ T N + L NYCRNPDG PWCH + ++ WEYC
Sbjct: 292 SGHTCQHWSAQTPHTHNRTPENFPCKNL---DENYCRNPDGKRAPWCHT-TNSQVRWEYC 347
Query: 1181 DLPQC 1195
+P C
Sbjct: 348 KIPSC 352
Score = 106 bits (264), Expect = 8e-23
Identities = 64/189 (33%), Positives = 86/189 (45%), Gaps = 19/189 (10%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPY-NGRRPDAVKLGLGNHNYCRNPDKD 862
C + G YRG + T SG C +W+ A P+ + R P+ + NYCRNPD
Sbjct: 275 CLKGTGENYRGNVAVTVSGHTCQHWS----AQTPHTHNRTPENFPCKNLDENYCRNPDGK 330
Query: 863 SKPWCYIFKAEKYIPDFCSTPAC------------------TKEKEECYTGKGLDYRGTR 988
PWC+ ++ ++C P+C T ++CY G G YRGT
Sbjct: 331 RAPWCHTTNSQVRW-EYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTS 389
Query: 989 SLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLT 1168
S T +G C W+S+ T N GL NYCRNPD D PWC D +
Sbjct: 390 STTTTGKKCQSWSSMTPHRHQKTP--ENYPNAGL-TMNYCRNPDADKGPWCFT-TDPSVR 445
Query: 1169 WEYCDLPQC 1195
WEYC+L +C
Sbjct: 446 WEYCNLKKC 454
Score = 64.3 bits (155), Expect = 3e-10
Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Frame = +2
Query: 947 ECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGD 1126
EC TG G +YRGT S T +G C W+S ++ ++ L + NYCRNPD D
Sbjct: 102 ECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGL---EENYCRNPDND 158
Query: 1127 TQ-PWCHVLKDHKLTWEYCDLPQC 1195
Q PWC+ D + ++YCD+ +C
Sbjct: 159 PQGPWCYT-TDPEKRYDYCDILEC 181
>ref|NP_005568.1| lipoprotein, Lp(a) [Homo sapiens]
Length = 4548
Score = 173 bits (438), Expect = 5e-43
Identities = 131/417 (31%), Positives = 190/417 (45%), Gaps = 28/417 (6%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRR-PDAVKLGLGNHNYCRNPDKD 862
CY G +YRGT+STT +G C +W++ P+ +R P+ NYCRNPD D
Sbjct: 4124 CYHGNGQSYRGTFSTTVTGRTCQSWSSM----TPHRHQRTPENYPNDGLTMNYCRNPDAD 4179
Query: 863 SKPWCYIFKAEKYIPDFCSTPACTK--------------------EKEECYTGKGLDYRG 982
+ PWC+ ++C+ C+ +++C G G YRG
Sbjct: 4180 TGPWCFTMDPSIRW-EYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRG 4238
Query: 983 TRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ-PWCHVLKDH 1159
++ T++G C W + + T + GL K NYCRNPDGD PWC+ +
Sbjct: 4239 KKATTVTGTPCQEWAAQE-PHRHSTFIPGTNKWAGLEK-NYCRNPDGDINGPWCYTMNPR 4296
Query: 1160 KLTWEYCDLPQCVT----CGLRQY--KEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGE 1321
KL ++YCD+P C + CG Q K+ I GG A S PWQ ++ R G+
Sbjct: 4297 KL-FDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSL----RTRFGK 4351
Query: 1322 RFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEF 1501
F CGG LIS WVL+AAHC ++ P +V+LG + Q EV + +
Sbjct: 4352 HF-CGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFL---- 4406
Query: 1502 DDDTYDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPF 1681
+ DIALL+L ++ +D V CLP + + TEC ++G+G E F
Sbjct: 4407 --EPTQADIALLKLSRPAVI----TDKVMPACLPSPDYMVTARTECYITGWG--ETQGTF 4458
Query: 1682 YSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
+ LKEA + + + C +CA G D+CQGDSGG
Sbjct: 4459 GTGLLKEAQLLVIENEVCNH---------YKYICAEHLARG------TDSCQGDSGG 4500
Score = 109 bits (272), Expect = 9e-24
Identities = 65/203 (32%), Positives = 92/203 (45%), Gaps = 33/203 (16%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ + + R P+ NYCRNPD +
Sbjct: 3562 CYYHYGQSYRGTYSTTVTGRTCQAWSSM---TPHQHSRTPENYPNAGLTRNYCRNPDAEI 3618
Query: 866 KPWCY----------------------IFKAEKYIPDFCSTPACTKEK--------EECY 955
+PWCY + +PD ST A ++E ++CY
Sbjct: 3619 RPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPD-PSTEASSEEAPTEQSPGVQDCY 3677
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTL---GLGKHNYCRNPDGD 1126
G G YRG+ S T++G C W+S+ W+ G NYCRNPD +
Sbjct: 3678 HGDGQSYRGSFSTTVTGRTCQSWSSMT------PHWHQRTTEYYPNGGLTRNYCRNPDAE 3731
Query: 1127 TQPWCHVLKDHKLTWEYCDLPQC 1195
PWC+ + D + WEYC+L QC
Sbjct: 3732 ISPWCYTM-DPNVRWEYCNLTQC 3753
Score = 108 bits (271), Expect = 1e-23
Identities = 60/195 (30%), Positives = 90/195 (46%), Gaps = 25/195 (12%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRG++STT +G C +W++ + ++ R + G NYCRNPD +
Sbjct: 3676 CYHGDGQSYRGSFSTTVTGRTCQSWSSM---TPHWHQRTTEYYPNGGLTRNYCRNPDAEI 3732
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK----------------------EECYTGKGLDYR 979
PWCY ++C+ C + ++CY G G YR
Sbjct: 3733 SPWCYTMDPNVRW-EYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYR 3791
Query: 980 GTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTL---GLGKHNYCRNPDGDTQPWCHVL 1150
G+ S T++G C W+S+ W+ G NYCRNPD + +PWC+ +
Sbjct: 3792 GSFSTTVTGRTCQSWSSMT------PHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTM 3845
Query: 1151 KDHKLTWEYCDLPQC 1195
D + WEYC+L QC
Sbjct: 3846 -DPSVRWEYCNLTQC 3859
Score = 107 bits (267), Expect = 3e-23
Identities = 64/202 (31%), Positives = 92/202 (45%), Gaps = 32/202 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPY-NGRRPDAVKLGLGNHNYCRNPDKD 862
CY G +YRG STT +G C +W++ +P+ + R P+ NYCRNPD
Sbjct: 4010 CYHGDGRSYRGISSTTVTGRTCQSWSSM----IPHWHQRTPENYPNAGLTENYCRNPDSG 4065
Query: 863 SKPWCYIFKAEKYIP-DFCSTPACTKEKE------------------------------E 949
+PWCY + + ++C+ C++ + +
Sbjct: 4066 KQPWCYT--TDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQ 4123
Query: 950 CYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDT 1129
CY G G YRGT S T++G C W+S+ T N L + NYCRNPD DT
Sbjct: 4124 CYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTM---NYCRNPDADT 4180
Query: 1130 QPWCHVLKDHKLTWEYCDLPQC 1195
PWC + D + WEYC+L +C
Sbjct: 4181 GPWCFTM-DPSIRWEYCNLTRC 4201
Score = 107 bits (267), Expect = 3e-23
Identities = 66/201 (32%), Positives = 88/201 (43%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLG-NHNYCRNPDKD 862
CY G +YRGT STT +G C +W++ P+ RR G NYCRNPD +
Sbjct: 3896 CYRGDGQSYRGTLSTTITGRTCQSWSSM----TPHWHRRIPLYYPNAGLTRNYCRNPDAE 3951
Query: 863 SKPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EEC 952
+PWCY ++C+ C + ++C
Sbjct: 3952 IRPWCYTMDPSVRW-EYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDC 4010
Query: 953 YTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ 1132
Y G G YRG S T++G C W+S++ T N GL NYCRNPD Q
Sbjct: 4011 YHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTP--ENYPNAGL-TENYCRNPDSGKQ 4067
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
PWC+ D + WEYC+L QC
Sbjct: 4068 PWCYT-TDPCVRWEYCNLTQC 4087
Score = 106 bits (265), Expect = 6e-23
Identities = 61/204 (29%), Positives = 93/204 (45%), Gaps = 34/204 (16%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRG++STT +G C +W++ + ++ R + G NYCRNPD +
Sbjct: 3782 CYHGDGQSYRGSFSTTVTGRTCQSWSSM---TPHWHQRTTEYYPNGGLTRNYCRNPDAEI 3838
Query: 866 KPWCYIFKAEKYIPDFCSTPAC------------------------------TKEKEECY 955
+PWCY ++C+ C + ++CY
Sbjct: 3839 RPWCYTMDPSVRW-EYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCY 3897
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNA----QTLGLGKHNYCRNPDG 1123
G G YRGT S T++G C W+S+ W+ GL + NYCRNPD
Sbjct: 3898 RGDGQSYRGTLSTTITGRTCQSWSSMT------PHWHRRIPLYYPNAGLTR-NYCRNPDA 3950
Query: 1124 DTQPWCHVLKDHKLTWEYCDLPQC 1195
+ +PWC+ + D + WEYC+L +C
Sbjct: 3951 EIRPWCYTM-DPSVRWEYCNLTRC 3973
Score = 101 bits (252), Expect = 2e-21
Identities = 61/202 (30%), Positives = 91/202 (45%), Gaps = 31/202 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGN-HNYCRNPDKD 862
CY G +Y+GT+ T +G C W++ P++ R A G NYCRNPD
Sbjct: 3448 CYHGNGQSYQGTYFITVTGRTCQAWSSM----TPHSHSRTPAYYPNAGLIKNYCRNPDPV 3503
Query: 863 SKPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EEC 952
+ PWCY ++C+ C+ + ++C
Sbjct: 3504 AAPWCYTTDPSVRW-EYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPGVQDC 3562
Query: 953 YTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ 1132
Y G YRGT S T++G C W+S+ ++ N GL + NYCRNPD + +
Sbjct: 3563 YYHYGQSYRGTYSTTVTGRTCQAWSSMT--PHQHSRTPENYPNAGLTR-NYCRNPDAEIR 3619
Query: 1133 PWCHVLKDHKLTWEYCDLPQCV 1198
PWC+ + D + WEYC+L QC+
Sbjct: 3620 PWCYTM-DPSVRWEYCNLTQCL 3640
Score = 100 bits (249), Expect = 4e-21
Identities = 65/201 (32%), Positives = 92/201 (45%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 3334 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDPVA 3390
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 3391 APYCYT-RDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECY 3449
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G Y+GT +T++G C W+S+ T A+ NA GL K NYCRNPD
Sbjct: 3450 HGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNA---GLIK-NYCRNPDPVAA 3505
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
PWC+ D + WEYC+L +C
Sbjct: 3506 PWCYT-TDPSVRWEYCNLTRC 3525
Score = 99.8 bits (247), Expect = 7e-21
Identities = 64/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W S + +N + GL NYCRNPD +
Sbjct: 28 CYHGDGQSYRGTYSTTVTGRTCQAW--SSMTPHQHNRTTENYPNAGL-IMNYCRNPDAVA 84
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 85 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 143
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 144 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 199
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 200 PYCYT-RDPGVRWEYCNLTQC 219
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 3220 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 3276
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 3277 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 3335
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 3336 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDPVAA 3391
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 3392 PYCYT-RDPSVRWEYCNLTQC 3411
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 3106 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 3162
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 3163 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 3221
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 3222 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 3277
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 3278 PYCYT-RDPGVRWEYCNLTQC 3297
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 2992 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 3048
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 3049 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 3107
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 3108 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 3163
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 3164 PYCYT-RDPGVRWEYCNLTQC 3183
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 2878 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 2934
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 2935 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 2993
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 2994 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 3049
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 3050 PYCYT-RDPGVRWEYCNLTQC 3069
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 2764 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 2820
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 2821 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 2879
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 2880 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 2935
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 2936 PYCYT-RDPGVRWEYCNLTQC 2955
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 2650 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 2706
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 2707 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 2765
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 2766 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 2821
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 2822 PYCYT-RDPGVRWEYCNLTQC 2841
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 2536 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 2592
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 2593 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 2651
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 2652 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 2707
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 2708 PYCYT-RDPGVRWEYCNLTQC 2727
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 2422 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 2478
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 2479 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 2537
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 2538 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 2593
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 2594 PYCYT-RDPGVRWEYCNLTQC 2613
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 2308 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 2364
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 2365 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 2423
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 2424 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 2479
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 2480 PYCYT-RDPGVRWEYCNLTQC 2499
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 2194 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 2250
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 2251 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 2309
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 2310 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 2365
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 2366 PYCYT-RDPGVRWEYCNLTQC 2385
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 2080 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 2136
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 2137 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 2195
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 2196 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 2251
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 2252 PYCYT-RDPGVRWEYCNLTQC 2271
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 1966 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 2022
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 2023 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 2081
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 2082 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 2137
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 2138 PYCYT-RDPGVRWEYCNLTQC 2157
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 1852 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 1908
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 1909 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 1967
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 1968 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 2023
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 2024 PYCYT-RDPGVRWEYCNLTQC 2043
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 1738 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 1794
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 1795 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 1853
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 1854 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 1909
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 1910 PYCYT-RDPGVRWEYCNLTQC 1929
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 1624 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 1680
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 1681 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 1739
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 1740 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 1795
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 1796 PYCYT-RDPGVRWEYCNLTQC 1815
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 1510 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 1566
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 1567 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 1625
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 1626 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 1681
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 1682 PYCYT-RDPGVRWEYCNLTQC 1701
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 1396 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 1452
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 1453 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 1511
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 1512 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 1567
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 1568 PYCYT-RDPGVRWEYCNLTQC 1587
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 1282 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 1338
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 1339 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 1397
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 1398 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 1453
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 1454 PYCYT-RDPGVRWEYCNLTQC 1473
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 1168 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 1224
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 1225 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 1283
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 1284 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 1339
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 1340 PYCYT-RDPGVRWEYCNLTQC 1359
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 1054 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 1110
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 1111 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 1169
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 1170 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 1225
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 1226 PYCYT-RDPGVRWEYCNLTQC 1245
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 940 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 996
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 997 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 1055
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 1056 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 1111
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 1112 PYCYT-RDPGVRWEYCNLTQC 1131
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 826 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 882
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 883 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 941
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 942 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 997
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 998 PYCYT-RDPGVRWEYCNLTQC 1017
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 712 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 768
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 769 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 827
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 828 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 883
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 884 PYCYT-RDPGVRWEYCNLTQC 903
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 598 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 654
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 655 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 713
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 714 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 769
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 770 PYCYT-RDPGVRWEYCNLTQC 789
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 484 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 540
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 541 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 599
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 600 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 655
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 656 PYCYT-RDPGVRWEYCNLTQC 675
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 370 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 426
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 427 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 485
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 486 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 541
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 542 PYCYT-RDPGVRWEYCNLTQC 561
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 256 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 312
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 313 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 371
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 372 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 427
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 428 PYCYT-RDPGVRWEYCNLTQC 447
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/201 (31%), Positives = 90/201 (44%), Gaps = 31/201 (15%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRGT+STT +G C W++ S + R P+ NYCRNPD +
Sbjct: 142 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHS---HSRTPEYYPNAGLIMNYCRNPDAVA 198
Query: 866 KPWCYIFKAEKYIPDFCSTPACTKEK------------------------------EECY 955
P+CY + ++C+ C+ + +ECY
Sbjct: 199 APYCYT-RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 257
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT-AWNSNAQTLGLGKHNYCRNPDGDTQ 1132
G G YRGT S T++G C W+S+ T + NA + NYCRNPD
Sbjct: 258 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVAA 313
Query: 1133 PWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 314 PYCYT-RDPGVRWEYCNLTQC 333
Score = 67.8 bits (164), Expect = 3e-11
Identities = 34/84 (40%), Positives = 46/84 (54%)
Frame = +2
Query: 944 EECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDG 1123
++CY G G YRGT S T++G C W+S+ + N GL NYCRNPD
Sbjct: 26 QDCYHGDGQSYRGTYSTTVTGRTCQAWSSMT--PHQHNRTTENYPNAGL-IMNYCRNPDA 82
Query: 1124 DTQPWCHVLKDHKLTWEYCDLPQC 1195
P+C+ +D + WEYC+L QC
Sbjct: 83 VAAPYCYT-RDPGVRWEYCNLTQC 105
>ref|XP_946885.1| PREDICTED: similar to Apolipoprotein(a) precursor (Apo(a)) (Lp(a))
[Homo sapiens]
Length = 440
Score = 151 bits (382), Expect = 2e-36
Identities = 115/366 (31%), Positives = 165/366 (45%), Gaps = 27/366 (7%)
Frame = +2
Query: 836 NYCRNPDKDSKPWCYIFKAEKYIPDFCSTPACTK--------------------EKEECY 955
NYCRNPD D+ PWC+ ++C+ C+ +++C
Sbjct: 2 NYCRNPDADTGPWCFTMDPSIRW-EYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCM 60
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ- 1132
G G YRG ++ T++G C W + + T + GL K NYCRNPDGD
Sbjct: 61 FGNGKGYRGKKATTVTGTPCQEWAAQE-PHRHSTFIPGTNKWAGLEK-NYCRNPDGDING 118
Query: 1133 PWCHVLKDHKLTWEYCDLPQCVT----CGLRQY--KEPQFRIKGGLYADITSHPWQAAIF 1294
PWC+ + KL ++YCD+P C + CG Q K+ I GG A S PWQ ++
Sbjct: 119 PWCYTMNPRKL-FDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSL- 176
Query: 1295 VKNRRSPGERFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEV 1474
R G+ F CGG LIS WVL+AAHC ++ P +V+LG + Q EV
Sbjct: 177 ---RTRFGKHF-CGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESHVQEIEV 232
Query: 1475 EKYIVHKEFDDDTYDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGY 1654
+ + + DIALL+L ++ +D V CLP + + TEC ++G+
Sbjct: 233 SRLFL------EPTQADIALLKLSRPAVI----TDKVMPACLPSPDYMVTARTECYITGW 282
Query: 1655 GKHEASSPFYSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDAC 1834
G E F + LKEA + + + C +CA G D+C
Sbjct: 283 G--ETQGTFGTGLLKEAQLLVIENEVCNH---------YKYICAEHLARG------TDSC 325
Query: 1835 QGDSGG 1852
QGDSGG
Sbjct: 326 QGDSGG 331
>ref|XP_931416.1| PREDICTED: similar to Apolipoprotein(a) precursor (Apo(a)) (Lp(a))
[Homo sapiens]
Length = 440
Score = 151 bits (382), Expect = 2e-36
Identities = 115/366 (31%), Positives = 165/366 (45%), Gaps = 27/366 (7%)
Frame = +2
Query: 836 NYCRNPDKDSKPWCYIFKAEKYIPDFCSTPACTK--------------------EKEECY 955
NYCRNPD D+ PWC+ ++C+ C+ +++C
Sbjct: 2 NYCRNPDADTGPWCFTMDPSIRW-EYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCM 60
Query: 956 TGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ- 1132
G G YRG ++ T++G C W + + T + GL K NYCRNPDGD
Sbjct: 61 FGNGKGYRGKKATTVTGTPCQEWAAQE-PHRHSTFIPGTNKWAGLEK-NYCRNPDGDING 118
Query: 1133 PWCHVLKDHKLTWEYCDLPQCVT----CGLRQY--KEPQFRIKGGLYADITSHPWQAAIF 1294
PWC+ + KL ++YCD+P C + CG Q K+ I GG A S PWQ ++
Sbjct: 119 PWCYTMNPRKL-FDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSL- 176
Query: 1295 VKNRRSPGERFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEV 1474
R G+ F CGG LIS WVL+AAHC ++ P +V+LG + Q EV
Sbjct: 177 ---RTRFGKHF-CGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESHVQEIEV 232
Query: 1475 EKYIVHKEFDDDTYDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGY 1654
+ + + DIALL+L ++ +D V CLP + + TEC ++G+
Sbjct: 233 SRLFL------EPTQADIALLKLSRPAVI----TDKVMPACLPSPDYMVTARTECYITGW 282
Query: 1655 GKHEASSPFYSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDAC 1834
G E F + LKEA + + + C +CA G D+C
Sbjct: 283 G--ETQGTFGTGLLKEAQLLVIENEVCNH---------YKYICAEHLARG------TDSC 325
Query: 1835 QGDSGG 1852
QGDSGG
Sbjct: 326 QGDSGG 331
Database: RefSeqHP
Posted date: Aug 2, 2006 12:57 AM
Number of letters in database: 17,774,539
Number of sequences in database: 39,411
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,350,516
Number of Sequences: 39411
Number of extensions: 3007668
Number of successful extensions: 16191
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 9195
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 15343
length of database: 17,774,539
effective HSP length: 108
effective length of database: 13,518,151
effective search space used: 6880738859
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqMP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20060611C-007176
(1854 letters)
Database: RefSeqMP
45,328 sequences; 21,768,885 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_032898.1| plasminogen activator, tissue [Mus musculus] 873 0.0
Alignment gi|NP_062320.1| hepatocyte growth factor activator [Mus musculus] 230 3e-60
Alignment gi|NP_067464.1| coagulation factor XII (Hageman factor) [Mus mu... 222 1e-57
Alignment gi|NP_666213.1| hyaluronic acid binding protein 2 [Mus musculus] 221 2e-57
Alignment gi|NP_032899.1| plasminogen activator, urokinase [Mus musculus] 218 2e-56
Alignment gi|NP_032903.2| plasminogen [Mus musculus] 203 6e-52
Alignment gi|NP_034557.2| hepatocyte growth factor [Mus musculus] 142 2e-33
Alignment gi|NP_032269.2| macrophage stimulating 1 (hepatocyte growth fac... 140 5e-33
Alignment gi|NP_032965.1| protease, serine, 12 neurotrypsin (motopsin) [M... 125 2e-28
Alignment gi|NP_056590.2| transmembrane protease, serine 2 [Mus musculus] 115 1e-25
>ref|NP_032898.1| plasminogen activator, tissue [Mus musculus]
Length = 559
Score = 873 bits (2256), Expect = 0.0
Identities = 392/513 (76%), Positives = 439/513 (85%), Gaps = 1/513 (0%)
Frame = +2
Query: 317 LKRELWCVLLLCGAICTSPSQETHXXXXXXXXXXXVTCRDEKTQMIYQQHQSWLRPLLRG 496
+KREL CVLLLCG P Q H TCRDE TQ YQQHQSWLRP+LR
Sbjct: 1 MKRELLCVLLLCGLAFPLPDQGIHGRFRRGARSYRATCRDEPTQTTYQQHQSWLRPMLRS 60
Query: 497 NRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDA 676
+RVE+C CN G QCHSVPV+SCSEPRCFNGGTC QA+YFSDFVCQCP GF+G++C+ID
Sbjct: 61 SRVEYCRCNSGLVQCHSVPVRSCSEPRCFNGGTCQQALYFSDFVCQCPDGFVGKRCDIDT 120
Query: 677 RATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPD 856
RATC+E+QGITYRGTWST ESGAEC+NWN+S L+ PYN RRP+A+KLGLGNHNYCRNPD
Sbjct: 121 RATCFEEQGITYRGTWSTAESGAECINWNSSVLSLKPYNARRPNAIKLGLGNHNYCRNPD 180
Query: 857 KDSKPWCYIFKAEKYIPDFCSTPACTKEK-EECYTGKGLDYRGTRSLTMSGAFCLPWNSL 1033
+D KPWCY+FKA KY +FCSTPAC K K E+CY GKG+ YRGT SLT S A CLPWNS+
Sbjct: 181 RDLKPWCYVFKAGKYTTEFCSTPACPKGKSEDCYVGKGVTYRGTHSLTTSQASCLPWNSI 240
Query: 1034 VLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVTCGLR 1213
VLMGK YTAW +N+Q LGL +HNYCRNPDGD +PWCHV+KD KLTWEYCD+ C TCGLR
Sbjct: 241 VLMGKSYTAWRTNSQALGLARHNYCRNPDGDARPWCHVMKDRKLTWEYCDMSPCSTCGLR 300
Query: 1214 QYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQER 1393
QYK PQFRIKGGLY DITSHPWQAAIFVKN+RSPGERFLCGG+LISSCWVLSAAHCF ER
Sbjct: 301 QYKRPQFRIKGGLYTDITSHPWQAAIFVKNKRSPGERFLCGGVLISSCWVLSAAHCFLER 360
Query: 1394 FPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDNDIALLQLKSDSLTCAQE 1573
FPP+H++VVLGRTYR+VPGEEEQ FE+EKYIVH+EFDDDTYDNDIALLQL+S S CAQE
Sbjct: 361 FPPNHLKVVLGRTYRVVPGEEEQTFEIEKYIVHEEFDDDTYDNDIALLQLRSQSKQCAQE 420
Query: 1574 SDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSSCCTSKHLF 1753
S +V T CLP+ NLQLPDWTECELSGYGKHEASSPF+S+RLKEAHVRLYPSS CTS+HLF
Sbjct: 421 SSSVGTACLPDPNLQLPDWTECELSGYGKHEASSPFFSDRLKEAHVRLYPSSRCTSQHLF 480
Query: 1754 NKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
NKT+T +MLCAGDTRSGG+ +LHDACQGDSGG
Sbjct: 481 NKTVTNNMLCAGDTRSGGNQ-DLHDACQGDSGG 512
>ref|NP_062320.1| hepatocyte growth factor activator [Mus musculus]
Length = 653
Score = 230 bits (587), Expect = 3e-60
Identities = 153/474 (32%), Positives = 217/474 (45%), Gaps = 44/474 (9%)
Frame = +2
Query: 563 CSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITY---RGTWSTT 733
C+ C NGGTC + C CP+ F G+ C + C+++ Y W+
Sbjct: 161 CASWPCLNGGTCSSTHDHGSYHCSCPLAFTGKDCGTE---KCFDETRYEYFEVGDHWARV 217
Query: 734 ESG-----------AECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCY 880
G A C + + + S P + +G G + C P + +C
Sbjct: 218 SEGHVEQCGCMEGQARCEDTHHTACLSSPCLNGGTCHLIVGTGT-SVCTCPLGYAGRFCN 276
Query: 881 IFKAEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTA 1060
I +P E C+ G G +YRG S SG CL WNS +L +++
Sbjct: 277 I------VP-----------TEHCFLGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVD 319
Query: 1061 WNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQC--------------- 1195
+ A LGLG H YCRNPD D +PWC+V+KD+ L+WEYC L C
Sbjct: 320 SVAAAVLLGLGPHAYCRNPDKDERPWCYVVKDNALSWEYCRLTACESLARVHSQTPEILA 379
Query: 1196 ----------VTCGLRQYKEP--QFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGG 1339
TCG R K + RI GG + SHPW AAI++ N C G
Sbjct: 380 ALPESAPAVRPTCGKRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGNS-------FCAG 432
Query: 1340 ILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYD 1519
L+ +CWV+SAAHCF P + VVLG+ + + Q F +EKY+ + + +
Sbjct: 433 SLVHTCWVVSAAHCFANSPPRDSITVVLGQHFFNRTTDVTQTFGIEKYVPYTLYSVFNPN 492
Query: 1520 N-DIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERL 1696
N D+ L++LK CA S V+ +CLPEA P +C+++G+G + + YS L
Sbjct: 493 NHDLVLIRLKKKGERCAVRSQFVQPICLPEAGSSFPTGHKCQIAGWGHMDENVSSYSNSL 552
Query: 1697 KEAHVRLYPSSCCTSKHLFNKTITKHMLCAG--DTRSGGDDANLHDACQGDSGG 1852
EA V L C+S ++ I+ +MLCAG D +S DACQGDSGG
Sbjct: 553 LEALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKS--------DACQGDSGG 598
Score = 131 bits (329), Expect = 3e-30
Identities = 65/168 (38%), Positives = 81/168 (48%)
Frame = +2
Query: 428 CRDEKTQMIYQQHQSWLRPLLRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQA 607
C DE ++ W R + VE C C +GQ +C +C C NGGTC
Sbjct: 199 CFDETRYEYFEVGDHWAR--VSEGHVEQCGCMEGQARCEDTHHTACLSSPCLNGGTCHLI 256
Query: 608 VYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMP 787
V VC CP+G+ GR C I C+ G YRG ST SG C+ WN+ L
Sbjct: 257 VGTGTSVCTCPLGYAGRFCNIVPTEHCFLGNGTEYRGVASTAASGLSCLAWNSDLLYQEL 316
Query: 788 YNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPAC 931
+ AV LGLG H YCRNPDKD +PWCY+ K ++C AC
Sbjct: 317 HVDSVAAAVLLGLGPHAYCRNPDKDERPWCYVVKDNALSWEYCRLTAC 364
>ref|NP_067464.1| coagulation factor XII (Hageman factor) [Mus musculus]
Length = 597
Score = 222 bits (565), Expect = 1e-57
Identities = 150/478 (31%), Positives = 220/478 (46%), Gaps = 3/478 (0%)
Frame = +2
Query: 428 CRDEKTQMIYQQHQSWLRPLLRGNRVEHCWCNDGQTQCHSVPVKSCSEPRCFNGGTCLQA 607
C + + + +++ W + G V C C + C V ++CS C NGG+CL
Sbjct: 135 CFEPQLLKFFHENELWFKTGPGG--VARCECKGSEAHCKPVASQACSINPCLNGGSCL-- 190
Query: 608 VYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMP 787
+ +C+CP G+ G C++D ATCYE +G++YRG TT+SGA C W
Sbjct: 191 LVEDHPLCRCPTGYTGYFCDLDLWATCYEGRGLSYRGQAGTTQSGAPCQRWTVEATYR-- 248
Query: 788 YNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPACTKEKEECYTGKG 967
N A+ GLG+H +CRNPD D++PWC+++ ++ D+C E+C T
Sbjct: 249 -NMTEKQALSWGLGHHAFCRNPDNDTRPWCFVWSGDRLSWDYCGL-------EQCQT--- 297
Query: 968 LDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHV 1147
P + +++ + S A +L P+ T
Sbjct: 298 -----------------PTFAPLVVPESQEESPSQAPSLS-------HAPNDST------ 327
Query: 1148 LKDHKLTWEYCDLPQCVTCGLRQYK--EPQFRIKGGLYADITSHPWQAAIFVKNRRSPGE 1321
DH+ + + CG R K R+ GGL A SHP+ AA++ N
Sbjct: 328 --DHQTS---LSKTNTMGCGQRFRKGLSSFMRVVGGLVALPGSHPYIAALYWGNN----- 377
Query: 1322 RFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEF 1501
C G LI+ CWVL+AAHC Q R P + VVLG+ E Q V Y +H+ F
Sbjct: 378 --FCAGSLIAPCWVLTAAHCLQNRPAPEELTVVLGQDRHNQSCEWCQTLAVRSYRLHEGF 435
Query: 1502 DDDTYDNDIALLQL-KSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSP 1678
TY +D+ALL+L +S + +CA S V+ VCLP + CE++G+G +
Sbjct: 436 SSITYQHDLALLRLQESKTNSCAILSPHVQPVCLPSGAAPPSETVLCEVAGWGHQLEGAE 495
Query: 1679 FYSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
YS L+EA V C++ ++ I MLCAG G DACQGDSGG
Sbjct: 496 EYSTFLQEAQVPFIALDRCSNSNVHGDAILPGMLCAGFLEGG------TDACQGDSGG 547
>ref|NP_666213.1| hyaluronic acid binding protein 2 [Mus musculus]
Length = 517
Score = 221 bits (564), Expect = 2e-57
Identities = 154/465 (33%), Positives = 213/465 (45%), Gaps = 35/465 (7%)
Frame = +2
Query: 563 CSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESG 742
C C +GG C+ + F C CP F G +C+ A+ C ++ + +
Sbjct: 34 CQSNPCEHGGDCI--IRGDTFSCSCPAPFSGSRCQT-AQNKCKDNPCVHGDCLITQKHPY 90
Query: 743 AECVNWNTSGLASMPYNGRRPDAVKL-------GLGNHNYCRNPDKDSKPWCYIFKAEKY 901
C PY G PD K+ N C + S+ C
Sbjct: 91 YRCA-------CKYPYTG--PDCSKVLPACRPNPCQNGGVCSRHRRRSRFTCAC------ 135
Query: 902 IPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQT 1081
PD C ++CY G G YRG S T++ CL WNS +L+ + Y + +A+T
Sbjct: 136 -PDQYKGKFCEIGPDDCYVGDGYSYRGKVSKTVNQNPCLYWNSHLLLQETYNMFMEDAET 194
Query: 1082 LGLGKHNYCRNPDGDTQPWCHV-LKDHKLTWEYCD----------------------LPQ 1192
G+ +HN+CRNPDGD +PWC V + K+ WEYCD LP
Sbjct: 195 HGIAEHNFCRNPDGDHKPWCFVKVNSEKVKWEYCDVTVCPVPDTPNPVESLLEPVMELPG 254
Query: 1193 CVTCGLRQYKEPQF-RIKGGLYADITSHPWQAAI--FVKNRRSPGERFLCGGILISSCWV 1363
+CG + E RI GG + HPWQ ++ + S + CGG LI CWV
Sbjct: 255 FESCGKTEVAEHAVKRIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGALIHPCWV 314
Query: 1364 LSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFD--DDTYDNDIALL 1537
L+AAHC H++VVLG EQ F VEK + + +++ D+ NDIALL
Sbjct: 315 LTAAHCTD--INTKHLKVVLGDQDLKKTESHEQTFRVEKILKYSQYNERDEIPHNDIALL 372
Query: 1538 QLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRL 1717
+LK CA ES V+TVCLP P TEC +SG+G E S +L +A V+L
Sbjct: 373 KLKPVGGHCALESRYVKTVCLPSD--PFPSGTECHISGWGVTETGEG--SRQLLDAKVKL 428
Query: 1718 YPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
+ C S+ L++ TI M+CAG+ + G D CQGDSGG
Sbjct: 429 IANPLCNSRQLYDHTIDDSMICAGNLQKPGS-----DTCQGDSGG 468
Score = 95.5 bits (236), Expect = 2e-19
Identities = 53/143 (37%), Positives = 69/143 (48%), Gaps = 3/143 (2%)
Frame = +2
Query: 512 CWCNDGQT--QCHSVPVKSCSEPRCFNGGTCLQAVYFSDFVCQCPVGFIGRQCEIDARAT 685
C C T C V + +C C NGG C + S F C CP + G+ CEI
Sbjct: 93 CACKYPYTGPDCSKV-LPACRPNPCQNGGVCSRHRRRSRFTCACPDQYKGKFCEI-GPDD 150
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 865
CY G +YRG S T + C+ WN+ L YN DA G+ HN+CRNPD D
Sbjct: 151 CYVGDGYSYRGKVSKTVNQNPCLYWNSHLLLQETYNMFMEDAETHGIAEHNFCRNPDGDH 210
Query: 866 KPWCYI-FKAEKYIPDFCSTPAC 931
KPWC++ +EK ++C C
Sbjct: 211 KPWCFVKVNSEKVKWEYCDVTVC 233
>ref|NP_032899.1| plasminogen activator, urokinase [Mus musculus]
Length = 433
Score = 218 bits (555), Expect = 2e-56
Identities = 118/317 (37%), Positives = 169/317 (53%), Gaps = 16/317 (5%)
Frame = +2
Query: 950 CYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDT 1129
CY G G YRG + G CL WN+ ++ K Y A +A +LGLGKHNYCRNPD
Sbjct: 71 CYHGNGDSYRGKANTDTKGRPCLAWNAPAVLQKPYNAHRPDAISLGLGKHNYCRNPDNQK 130
Query: 1130 QPWCHVLKDHKLTWEYCDLPQC--------------VTCGLRQYKEPQFRIKGGLYADIT 1267
+PWC+V + + C + C CG + + P+F+I GG + ++
Sbjct: 131 RPWCYVQIGLRQFVQECMVHDCSLSKKPSSSVDQQGFQCGQKALR-PRFKIVGGEFTEVE 189
Query: 1268 SHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVP 1447
+ PW AAI+ KN+ F CGG LIS CWV SAAHCF + + V LG++
Sbjct: 190 NQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVVYLGQSKESSY 249
Query: 1448 GEEEQAFEVEKYIVHKEFDDDT--YDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQL 1621
E FEVE+ I+H+ + +D+ Y NDIALL++++ + CAQ S +++T+CLP
Sbjct: 250 NPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQTICLPPRFTDA 309
Query: 1622 PDWTECELSGYGKHEASSPFYSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRS 1801
P ++CE++G+GK S Y + LK + V+L C H + I MLCA D
Sbjct: 310 PFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINYKMLCAADPEW 369
Query: 1802 GGDDANLHDACQGDSGG 1852
D+C+GDSGG
Sbjct: 370 ------KTDSCKGDSGG 380
Score = 126 bits (317), Expect = 7e-29
Identities = 56/124 (45%), Positives = 67/124 (54%), Gaps = 1/124 (0%)
Frame = +2
Query: 578 CFNGGTCLQAVYFSDFV-CQCPVGFIGRQCEIDARATCYEDQGITYRGTWSTTESGAECV 754
C NGG C+ YFS C CP F G CEIDA TCY G +YRG +T G C+
Sbjct: 34 CQNGGVCVSYKYFSRIRRCSCPRKFQGEHCEIDASKTCYHGNGDSYRGKANTDTKGRPCL 93
Query: 755 NWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIPDFCSTPACT 934
WN + PYN RPDA+ LGLG HNYCRNPD +PWCY+ + C C+
Sbjct: 94 AWNAPAVLQKPYNAHRPDAISLGLGKHNYCRNPDNQKRPWCYVQIGLRQFVQECMVHDCS 153
Query: 935 KEKE 946
K+
Sbjct: 154 LSKK 157
>ref|NP_032903.2| plasminogen [Mus musculus]
Length = 812
Score = 203 bits (516), Expect = 6e-52
Identities = 142/422 (33%), Positives = 197/422 (46%), Gaps = 33/422 (7%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRR-----PDAVKLGLGNHNYCRN 850
CY+ G +YRGT STT +G +C +W A P+ + PDA GL NYCRN
Sbjct: 377 CYQSDGQSYRGTSSTTITGKKCQSW----AAMFPHRHSKTPENFPDA---GL-EMNYCRN 428
Query: 851 PDKDSKPWCYIFKAEKYIPDFCSTPACTK--------------------EKEECYTGKGL 970
PD D PWCY ++C+ C++ + +C G G
Sbjct: 429 PDGDKGPWCYTTDPSVRW-EYCNLKRCSETGGSVVELPTVSQEPSGPSDSETDCMYGNGK 487
Query: 971 DYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ-PWCHV 1147
DYRG ++T +G C W + +N + GL K NYCRNPDGD PWC+
Sbjct: 488 DYRGKTAVTAAGTPCQGWAAQEPHRHSIFTPQTNPRA-GLEK-NYCRNPDGDVNGPWCYT 545
Query: 1148 LKDHKLTWEYCDLPQCVTCGLRQYKEPQF-------RIKGGLYADITSHPWQAAIFVKNR 1306
KL ++YCD+P C + + +PQ R+ GG A+ S PWQ ++
Sbjct: 546 TNPRKL-YDYCDIPLCASASSFECGKPQVEPKKCPGRVVGGCVANPHSWPWQISL---RT 601
Query: 1307 RSPGERFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYI 1486
R G+ F CGG LI+ WVL+AAHC ++ P +V+LG + G + Q V K I
Sbjct: 602 RFTGQHF-CGGTLIAPEWVLTAAHCLEKSSRPEFYKVILGAHEEYIRGSDVQEISVAKLI 660
Query: 1487 VHKEFDDDTYDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHE 1666
+ + + DIALL+L A +D V CLP N + D T C ++G+G E
Sbjct: 661 L------EPNNRDIALLKLSRP----ATITDKVIPACLPSPNYMVADRTICYITGWG--E 708
Query: 1667 ASSPFYSERLKEAHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDS 1846
F + RLKEA + + + C N + LCAG G D+CQGDS
Sbjct: 709 TQGTFGAGRLKEAQLPVIENKVCNRVEYLNNRVKSTELCAGQLAGG------VDSCQGDS 762
Query: 1847 GG 1852
GG
Sbjct: 763 GG 764
Score = 117 bits (293), Expect = 4e-26
Identities = 69/174 (39%), Positives = 85/174 (48%), Gaps = 2/174 (1%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLG-NHNYCRNPDKD 862
C G YRGT S T+SG C W A+ P+ + G NYCRNPD D
Sbjct: 103 CKTGIGNGYRGTMSRTKSGVACQKWG----ATFPHVPNYSPSTHPNEGLEENYCRNPDND 158
Query: 863 SK-PWCYIFKAEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVL 1039
+ PWCY +K D+C+ P C +EEC G Y G S TMSG C W+S
Sbjct: 159 EQGPWCYTTDPDKRY-DYCNIPEC---EEECMYCSGEKYEGKISKTMSGLDCQAWDSQSP 214
Query: 1040 MGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVT 1201
Y ++ L K NYCRNPDG+ +PWC K WEYCD+P+C T
Sbjct: 215 HAHGYIPAKFPSKNL---KMNYCRNPDGEPRPWCFTTDPTK-RWEYCDIPRCTT 264
Score = 116 bits (291), Expect = 7e-26
Identities = 65/185 (35%), Positives = 91/185 (49%), Gaps = 7/185 (3%)
Frame = +2
Query: 662 CEI-DARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHN 838
C I + C G Y G S T SG +C W++ + Y + + L + N
Sbjct: 176 CNIPECEEECMYCSGEKYEGKISKTMSGLDCQAWDSQSPHAHGYIPAKFPSKNLKM---N 232
Query: 839 YCRNPDKDSKPWCYIFKAEKYIPDFCSTPACTKEKE------ECYTGKGLDYRGTRSLTM 1000
YCRNPD + +PWC+ K ++C P CT +C G+G +YRGT S+T+
Sbjct: 233 YCRNPDGEPRPWCFTTDPTKRW-EYCDIPRCTTPPPPPSPTYQCLKGRGENYRGTVSVTV 291
Query: 1001 SGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYC 1180
SG C W+ T N + L + NYCRNPDG+T PWC+ D +L WEYC
Sbjct: 292 SGKTCQRWSEQTPHRHNRTPENFPCKNL---EENYCRNPDGETAPWCYT-TDSQLRWEYC 347
Query: 1181 DLPQC 1195
++P C
Sbjct: 348 EIPSC 352
Score = 114 bits (284), Expect = 5e-25
Identities = 66/193 (34%), Positives = 90/193 (46%), Gaps = 19/193 (9%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPY-NGRRPDAVKLGLGNHNYCRNPDKD 862
C + +G YRGT S T SG C W+ P+ + R P+ NYCRNPD +
Sbjct: 275 CLKGRGENYRGTVSVTVSGKTCQRWSEQ----TPHRHNRTPENFPCKNLEENYCRNPDGE 330
Query: 863 SKPWCYIFKAEKYIPDFCSTPAC------------------TKEKEECYTGKGLDYRGTR 988
+ PWCY ++ ++C P+C T +ECY G YRGT
Sbjct: 331 TAPWCYTTDSQLRW-EYCEIPSCESSASPDQSDSSVPPEEQTPVVQECYQSDGQSYRGTS 389
Query: 989 SLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLT 1168
S T++G C W + ++ N GL + NYCRNPDGD PWC+ D +
Sbjct: 390 STTITGKKCQSW--AAMFPHRHSKTPENFPDAGL-EMNYCRNPDGDKGPWCYT-TDPSVR 445
Query: 1169 WEYCDLPQCVTCG 1207
WEYC+L +C G
Sbjct: 446 WEYCNLKRCSETG 458
Score = 64.3 bits (155), Expect = 4e-10
Identities = 36/84 (42%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Frame = +2
Query: 947 ECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGD 1126
EC TG G YRGT S T SG C W + Y+ S GL + NYCRNPD D
Sbjct: 102 ECKTGIGNGYRGTMSRTKSGVACQKWGATFPHVPNYSP--STHPNEGL-EENYCRNPDND 158
Query: 1127 TQ-PWCHVLKDHKLTWEYCDLPQC 1195
Q PWC+ K ++YC++P+C
Sbjct: 159 EQGPWCYTTDPDK-RYDYCNIPEC 181
>ref|NP_034557.2| hepatocyte growth factor [Mus musculus]
Length = 728
Score = 142 bits (357), Expect = 2e-33
Identities = 106/410 (25%), Positives = 171/410 (41%), Gaps = 21/410 (5%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPY-NGRRPDAVKLGLGNHNYCRNPDKD 862
C + QG YRGT +T +G C W++ P+ + P+ K NYCRNPD
Sbjct: 306 CIQGQGEGYRGTSNTIWNGIPCQRWDSQ----YPHKHDITPENFKCKDLRENYCRNPDGA 361
Query: 863 SKPWCYIFKAEKYIPDFCSTPAC-TKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVL 1039
PWC+ + P C ++CY G G +Y G S T SG C W+ +
Sbjct: 362 ESPWCFTTDPNIRVGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWDKNME 421
Query: 1040 MGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ-PWCHVLKDHKLTWEYCDLPQC------- 1195
+ W +A L NYCRNPD D PWC+ + + W+YC + +C
Sbjct: 422 DLHRHIFWEPDASKL---NKNYCRNPDDDAHGPWCYT-GNPLIPWDYCPISRCEGDTTPT 477
Query: 1196 --------VTCGLRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILIS 1351
++C K Q R+ G+ T+ W ++ +N+ +CGG LI
Sbjct: 478 IVNLDHPVISCA----KTKQLRVVNGIPTQ-TTVGWMVSLKYRNKH------ICGGSLIK 526
Query: 1352 SCWVLSAAHCFQER---FPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDN 1522
WV++A CF R + + + + + +Q + + + E +
Sbjct: 527 ESWVITARQCFPARNKDLKDYEAWLGIHDVHERGEEKRKQILNISQLVYGPE------GS 580
Query: 1523 DIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKE 1702
D+ LL+L ++ + V T+ LP +P+ T C + G+G + L+
Sbjct: 581 DLVLLKLARPAIL----DNFVSTIDLPSYGCTIPEKTTCSIYGWGYTGLINA--DGLLRV 634
Query: 1703 AHVRLYPSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
AH+ + + C+ H T+ + LCAG + G C+GD GG
Sbjct: 635 AHLYIMGNEKCSQHHQGKVTLNESELCAGAEKIGS------GPCEGDYGG 678
Score = 95.1 bits (235), Expect = 2e-19
Identities = 61/186 (32%), Positives = 85/186 (45%), Gaps = 5/186 (2%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTS---GLASMPYNGRRPDAVKLGLGNHNYCRNP- 853
C +G +Y+GT S T+SG +C WN+ + +P + R D NYCRNP
Sbjct: 129 CIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDL------QENYCRNPR 182
Query: 854 DKDSKPWCYIFKAE-KYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNS 1030
++ PWC+ E +Y + C P C++ EC T G YRG T SG C W+
Sbjct: 183 GEEGGPWCFTSNPEVRY--EVCDIPQCSEV--ECMTCNGESYRGPMDHTESGKTCQRWDQ 238
Query: 1031 LVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVTCGL 1210
+ + NYCRNPDG +PWC+ L D TWEYC + C +
Sbjct: 239 QTPHRHKFLPERYPDKGFD---DNYCRNPDGKPRPWCYTL-DPDTTWEYCAIKTCAHSAV 294
Query: 1211 RQYKEP 1228
+ P
Sbjct: 295 NETDVP 300
Score = 92.0 bits (227), Expect = 2e-18
Identities = 72/227 (31%), Positives = 92/227 (40%), Gaps = 16/227 (7%)
Frame = +2
Query: 563 CSEPRCFNGG----TCLQAVYFSDFVCQCPVGFIGRQCEIDARATCYEDQGITYRGTWST 730
C PR GG T V + VC P QC + C G +YRG
Sbjct: 178 CRNPRGEEGGPWCFTSNPEVRYE--VCDIP------QC---SEVECMTCNGESYRGPMDH 226
Query: 731 TESGAECVNWNTSGLASMPYNGRR-PDAVKLGLGNHNYCRNPDKDSKPWCYIFKAEKYIP 907
TESG C W+ + R PD G + NYCRNPD +PWCY +
Sbjct: 227 TESGKTCQRWDQQTPHRHKFLPERYPDK---GFDD-NYCRNPDGKPRPWCYTLDPDTTW- 281
Query: 908 DFCSTPACTK----------EKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYT 1057
++C+ C E EC G+G YRGT + +G C W+S T
Sbjct: 282 EYCAIKTCAHSAVNETDVPMETTECIQGQGEGYRGTSNTIWNGIPCQRWDSQYPHKHDIT 341
Query: 1058 AWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYC-DLPQC 1195
N + L + NYCRNPDG PWC D + YC +P+C
Sbjct: 342 PENFKCKDL---RENYCRNPDGAESPWCFT-TDPNIRVGYCSQIPKC 384
Score = 70.9 bits (172), Expect = 4e-12
Identities = 38/106 (35%), Positives = 55/106 (51%), Gaps = 6/106 (5%)
Frame = +2
Query: 950 CYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDT 1129
C GKG Y+GT S+T SG C PWNS++ + + + L + NYCRNP G+
Sbjct: 129 CIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDL---QENYCRNPRGEE 185
Query: 1130 -QPWCHVLKDHKLTWEYCDLPQ-----CVTCGLRQYKEPQFRIKGG 1249
PWC + ++ +E CD+PQ C+TC Y+ P + G
Sbjct: 186 GGPWCFT-SNPEVRYEVCDIPQCSEVECMTCNGESYRGPMDHTESG 230
Score = 60.8 bits (146), Expect = 5e-09
Identities = 35/93 (37%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = +2
Query: 659 QCEIDARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHN 838
+C++ + CY G Y G S T SG C W+ + + PDA KL N N
Sbjct: 383 KCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWDKNMEDLHRHIFWEPDASKL---NKN 439
Query: 839 YCRNPDKDSK-PWCYIFKAEKYIP-DFCSTPAC 931
YCRNPD D+ PWCY IP D+C C
Sbjct: 440 YCRNPDDDAHGPWCY--TGNPLIPWDYCPISRC 470
>ref|NP_032269.2| macrophage stimulating 1 (hepatocyte growth factor-like) [Mus
musculus]
Length = 716
Score = 140 bits (353), Expect = 5e-33
Identities = 123/414 (29%), Positives = 178/414 (42%), Gaps = 25/414 (6%)
Frame = +2
Query: 686 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRR-PDAVKLGLGNHNYCRNPDKD 862
C+ +G YRGT +TT +G C W+ A P+ R P+ N+CRNPD
Sbjct: 292 CFRGKGEDYRGTTNTTSAGVPCQRWD----AQSPHQHRFVPEKYACKDLRENFCRNPDGS 347
Query: 863 SKPWCYIFKAEKYIPDFCSTPACTKE--KEECYTGKGLDYRGTRSLTMSGAFCLPWNSLV 1036
PWC+ + + P CT+E E CY G G YRG+ S T G C W+S
Sbjct: 348 EAPWCFTSRPGLRMAFCHQIPRCTEELVPEGCYHGSGEQYRGSVSKTRKGVQCQHWSSET 407
Query: 1037 LMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ-PWCHVLKDHKLTWEYCDLPQC------ 1195
+T ++A GL + N+CRNPDGD+ PWC+ L D + ++YC L +C
Sbjct: 408 PHKPQFTP--TSAPQAGL-EANFCRNPDGDSHGPWCYTL-DPDILFDYCALQRCDDDQPP 463
Query: 1196 -----------VTCGLRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGI 1342
CG R K + R+ GG HP + V R G+ F CGG
Sbjct: 464 SILDPPDQVVFEKCGKRVDKSNKLRVVGG-------HPGNSPWTVSLRNRQGQHF-CGGS 515
Query: 1343 LISSCWVLSAAHCFQERFPP-HHVRVVLGR-TYRLVPGEEE-QAFEVEKYIVHKEFDDDT 1513
L+ WVL+A C P V LG PGE Q V K +
Sbjct: 516 LVKEQWVLTARQCIWSCHEPLTGYEVWLGTINQNPQPGEANLQRVPVAKAVC------GP 569
Query: 1514 YDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSER 1693
+ + LL+L+ + + V +CLP +P T+CE++G+G+ +S +
Sbjct: 570 AGSQLVLLKLERPVIL----NHHVALICLPPEQYVVPPGTKCEIAGWGESIGTS--NNTV 623
Query: 1694 LKEAHVRLYPSSCCTSKHLFNKTITKHMLC-AGDTRSGGDDANLHDACQGDSGG 1852
L A + + + C +K + I + +C G G AC+GD GG
Sbjct: 624 LHVASMNVISNQECNTK--YRGHIQESEICPQGMVVPVG-------ACEGDYGG 668
Score = 96.7 bits (239), Expect = 8e-20
Identities = 60/172 (34%), Positives = 77/172 (44%), Gaps = 1/172 (0%)
Frame = +2
Query: 683 TCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKD 862
TC D G++YRGT + T G C W+ P + + K GL N+CRNPD D
Sbjct: 109 TCIMDNGVSYRGTVARTAGGLPCQAWSRR----FPNDHKYTPTPKNGL-EENFCRNPDGD 163
Query: 863 SK-PWCYIFKAEKYIPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVL 1039
+ PWCY C C + C G DYRG +T SG C W+
Sbjct: 164 PRGPWCYTTNRSVRFQS-CGIKTC--REAVCVLCNGEDYRGEVDVTESGRECQRWDLQHP 220
Query: 1040 MGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQC 1195
+ + L K NYCRNPDG +PWC+ D + E+CDLP C
Sbjct: 221 HSHPFQPEKFLDKDL---KDNYCRNPDGSERPWCYT-TDPNVEREFCDLPSC 268
Score = 93.6 bits (231), Expect = 6e-19
Identities = 61/190 (32%), Positives = 81/190 (42%), Gaps = 18/190 (9%)
Frame = +2
Query: 680 ATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDK 859
A C G YRG TESG EC W+ S P+ +P+ NYCRNPD
Sbjct: 189 AVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPF---QPEKFLDKDLKDNYCRNPDG 245
Query: 860 DSKPWCYIFKAEKYIPDFCSTPAC----------------TKEKE-ECYTGKGLDYRGTR 988
+PWCY +FC P+C K K C+ GKG DYRGT
Sbjct: 246 SERPWCYTTDPNVE-REFCDLPSCGPNLPPTVKGSKSQRRNKGKALNCFRGKGEDYRGTT 304
Query: 989 SLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLT 1168
+ T +G C W++ + + L + N+CRNPDG PWC + L
Sbjct: 305 NTTSAGVPCQRWDAQSPHQHRFVPEKYACKDL---RENFCRNPDGSEAPWCFTSRP-GLR 360
Query: 1169 WEYC-DLPQC 1195
+C +P+C
Sbjct: 361 MAFCHQIPRC 370
>ref|NP_032965.1| protease, serine, 12 neurotrypsin (motopsin) [Mus musculus]
Length = 761
Score = 125 bits (313), Expect = 2e-28
Identities = 85/222 (38%), Positives = 119/222 (53%), Gaps = 5/222 (2%)
Frame = +2
Query: 1202 CGLRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLSAAHC 1381
CGLR Q RI GG + + PWQA++ +++ G R LCG L+SSCWVL+AAHC
Sbjct: 505 CGLRLLHRRQKRIIGGNNSLRGAWPWQASLRLRSAHGDG-RLLCGATLLSSCWVLTAAHC 563
Query: 1382 FQE---RFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDNDIALLQLKSD 1552
F+ + VRV G + LVP E EQ V++ ++H+ + D D DIAL++L+
Sbjct: 564 FKRYGNNSRSYAVRV--GDYHTLVPEEFEQEIGVQQIVIHRNYRPDRSDYDIALVRLQGP 621
Query: 1553 SLTCAQESDAVRTVCLPEANLQLPDWT--ECELSGYGKHEASSPFYSERLKEAHVRLYPS 1726
CA+ S V CLP + P T C ++G+G + YS L++A V L P
Sbjct: 622 GEQCARLSTHVLPACLPLWR-ERPQKTASNCHITGWGD---TGRAYSRTLQQAAVPLLPK 677
Query: 1727 SCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
C K + T MLCAG+ + + N D+CQGDSGG
Sbjct: 678 RFC--KERYKGLFTGRMLCAGNLQ----EDNRVDSCQGDSGG 713
>ref|NP_056590.2| transmembrane protease, serine 2 [Mus musculus]
Length = 490
Score = 115 bits (289), Expect = 1e-25
Identities = 81/224 (36%), Positives = 113/224 (50%), Gaps = 3/224 (1%)
Frame = +2
Query: 1190 QCVTCGLRQYKEPQFRIKGGLYADITSHPWQAAIFVKNRRSPGERFLCGGILISSCWVLS 1369
+C+ CG+R K Q RI GGL A PWQ ++ V+ +CGG +I+ W+++
Sbjct: 239 RCIECGVRSVKR-QSRIVGGLNASPGDWPWQVSLHVQGVH------VCGGSIITPEWIVT 291
Query: 1370 AAHCFQERFP-PHHVRVVLG--RTYRLVPGEEEQAFEVEKYIVHKEFDDDTYDNDIALLQ 1540
AAHC +E P + G R + G Q VEK I H +D T +NDIAL++
Sbjct: 292 AAHCVEEPLSSPRYWTAFAGILRQSLMFYGSRHQ---VEKVISHPNYDSKTKNNDIALMK 348
Query: 1541 LKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEASSPFYSERLKEAHVRLY 1720
L+ T +D V+ VCLP + L EC +SG+G S+ L A V L
Sbjct: 349 LQ----TPLAFNDLVKPVCLPNPGMMLDLDQECWISGWGATYEKGKT-SDVLNAAMVPLI 403
Query: 1721 PSSCCTSKHLFNKTITKHMLCAGDTRSGGDDANLHDACQGDSGG 1852
S C SK+++N IT M+CAG + D+CQGDSGG
Sbjct: 404 EPSKCNSKYIYNNLITPAMICAGFLQGS------VDSCQGDSGG 441
Database: RefSeqMP
Posted date: Aug 2, 2006 12:58 AM
Number of letters in database: 21,768,885
Number of sequences in database: 45,328
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 104,168,460
Number of Sequences: 45328
Number of extensions: 3325529
Number of successful extensions: 16256
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 9730
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 15422
length of database: 21,768,885
effective HSP length: 109
effective length of database: 16,828,133
effective search space used: 8548691564
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)