Animal-Genome cDNA 20110601C-002572

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-002572
         (1561 letters)

Database: RefSeq49_BP.fasta 
           33,088 sequences; 17,681,374 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_001039353.1| procollagen C-endopeptidase enhancer 1 [Bos ...   714   0.0  
Alignment   gi|NP_001069097.1| procollagen C-endopeptidase enhancer 2 [Bos ...   360   2e-99
Alignment   gi|XP_002689817.1| PREDICTED: bone morphogenetic protein 1-like...   175   9e-44
Alignment   gi|XP_001788250.1| PREDICTED: bone morphogenetic protein 1-like...   167   2e-41
Alignment   gi|XP_002698454.1| PREDICTED: tolloid-like 2-like [Bos taurus].      166   7e-41
Alignment   gi|XP_869787.2| PREDICTED: tolloid-like 2-like isoform 2 [Bos t...   166   7e-41
Alignment   gi|NP_001180043.1| tolloid-like 1 [Bos taurus].                      163   3e-40
Alignment   gi|XP_002694354.1| PREDICTED: tolloid-like 1 [Bos taurus].           163   3e-40
Alignment   gi|XP_002686427.1| PREDICTED: CUB domain containing protein 2-l...   157   3e-38
Alignment   gi|XP_594473.4| PREDICTED: CUB domain containing protein 2 [Bos...   154   2e-37

>ref|NP_001039353.1| procollagen C-endopeptidase enhancer 1 [Bos taurus].
          Length = 451

 Score =  714 bits (1842), Expect = 0.0
 Identities = 355/459 (77%), Positives = 371/459 (80%), Gaps = 6/459 (1%)
 Frame = +2

Query: 203  MLPAATASXXXXXXXXXXXXX-FAQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPP 379
            MLPAATAS              F  GQTPNYTRPVFLCGGDVTGESGY+ASEGFPNLYPP
Sbjct: 1    MLPAATASLLGPLLTAWALLLPFTHGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPP 60

Query: 380  NKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAP 559
            NKECIWTITVP+SQTVSLSFRVFDLE HPSCRYDALE+FAGSGTSGQ+LGRFCGTFRPAP
Sbjct: 61   NKECIWTITVPKSQTVSLSFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAP 120

Query: 560  LVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESD 739
            +VA GNQVTLRM SDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESD
Sbjct: 121  VVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESD 180

Query: 740  YPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDK 919
            YPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNG VSDDAKRLGKFCGD 
Sbjct: 181  YPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDT 240

Query: 920  APGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGATEKAPAQ-----SPGEDARXXX 1084
             PG I+SEGNELLVQFVSDLSVTADGFSASYRT PRGATE  P +      PG   +   
Sbjct: 241  VPGSITSEGNELLVQFVSDLSVTADGFSASYRTQPRGATEGVPGEVGLGPKPGAGPK--- 297

Query: 1085 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSDGPSVPCPKQCRRTGTLQSNFC 1264
                                                G D PSV CPKQCRRTGTLQS+FC
Sbjct: 298  --------------VKPEVPPEEKSKAAPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFC 343

Query: 1265 NSNLVVTATVKSMVRGPGEGLTVTVSLIGVYKTGGLDLPSPPTDTSLKFYAPCKQCPPMK 1444
            NS+LVVT  +KSMVRGPGEGLT TV++ GVYKTGGLDLPSPPTDT LKFY PCKQCPPMK
Sbjct: 344  NSDLVVTGMIKSMVRGPGEGLTATVNVTGVYKTGGLDLPSPPTDTLLKFYVPCKQCPPMK 403

Query: 1445 KGTSYLMMGQVDENRGPILPPESFVVLYRPNQGQILTKL 1561
            KG SYL+MGQVD+NRGPILPPESFVVL+RP Q QILT L
Sbjct: 404  KGISYLLMGQVDKNRGPILPPESFVVLHRPTQHQILTNL 442


>ref|NP_001069097.1| procollagen C-endopeptidase enhancer 2 [Bos taurus].
          Length = 416

 Score =  360 bits (923), Expect = 2e-99
 Identities = 190/434 (43%), Positives = 260/434 (59%), Gaps = 3/434 (0%)
 Frame = +2

Query: 269  AQGQTPNYT-RPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRV 445
            AQ   P  + RPVF CGG +TGESG++ SEGFP +YPPN +C W ITVPE + V L+FR 
Sbjct: 18   AQHSRPQLSERPVFTCGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRF 77

Query: 446  FDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRG 625
             DLE    CRYD ++V+ G   +GQR+GRFCGTFRP  LV+  N++ ++M SD  T G G
Sbjct: 78   IDLESDNLCRYDFVDVYNGHA-NGQRIGRFCGTFRPGALVSSSNKMMVQMISDANTAGNG 136

Query: 626  FLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLT 805
            F+  +S    +    Q+CGG LE+  G+  TPNWP+ DYP G++C WHI+AP +Q+I L 
Sbjct: 137  FMAMFSAAEPNERGDQYCGGLLERPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELK 196

Query: 806  FGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSV 985
            F KFD+E D+YCRYD V+VFNG   +DA+R+GK+CGD  P PI SE NELL+QF+SDLS+
Sbjct: 197  FEKFDVERDNYCRYDYVAVFNGGEINDAERIGKYCGDSPPAPIVSERNELLIQFLSDLSL 256

Query: 986  TADGFSASYRTLPRGATEKAPAQSPGEDARXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1165
            TADGF   Y+  P+    K P  +                                    
Sbjct: 257  TADGFIGHYKFRPK----KLPTTT---------------------------------ALP 279

Query: 1166 XXXXXXXXXGSDGPSVPCPKQ-CRRTGTLQSNFCNSNLVVTATVKSMVRGPGEGLTVTVS 1342
                      S  P+V   +Q CRR+GTL SN+C+SN V+  TV + +   G  L  TVS
Sbjct: 280  VTTTFPVSTTSLKPTVALCQQKCRRSGTLGSNYCSSNFVLAGTVITTI-PRGGSLHATVS 338

Query: 1343 LIGVYKTGGLDLPSPPTDTSLKFYAPCKQCPPMKKGTSYLMMGQVDEN-RGPILPPESFV 1519
            +I +YK G L +     + S K    CKQCP +++G +Y++MGQV E+ RG I+ P SF+
Sbjct: 339  IINIYKEGNLAIQQAGKNMSAKVLVVCKQCPLLRRGLNYIIMGQVGEDGRGKIM-PNSFI 397

Query: 1520 VLYRPNQGQILTKL 1561
            ++++    ++L  L
Sbjct: 398  MMFKTKNQKLLDAL 411


>ref|XP_002689817.1| PREDICTED: bone morphogenetic protein 1-like [Bos taurus].
          Length = 946

 Score =  175 bits (444), Expect = 9e-44
 Identities = 90/235 (38%), Positives = 137/235 (58%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGGDV  ++G++ S  +P+ Y P+K C+W I V E   V L+F+ F++E H SC YD L
Sbjct: 436  ICGGDVKKDNGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVGLTFQSFEIERHDSCAYDYL 495

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTE 667
            EV  G   S   +GR+CG  +P  + +  +++ L+  SD      GF + +   A     
Sbjct: 496  EVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKAA----- 550

Query: 668  HQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRY 847
               CGG L K  G++T+P WP+ +YPP  +C W ++AP    ISL F  F+ E +  C+Y
Sbjct: 551  ---CGGFLTKLNGSITSPGWPK-EYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKY 606

Query: 848  DSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
            D V V +G ++ D+K  GKFCG + P  I+S+ N + V+F SD +V+  GF A +
Sbjct: 607  DFVEVRSG-LTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 660



 Score =  160 bits (406), Expect = 2e-39
 Identities = 85/237 (35%), Positives = 128/237 (54%), Gaps = 3/237 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   VT  SG + S  +P+ YP  KEC W I+      V L+F   D+E  P C YD LE
Sbjct: 707  CDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 766

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V+ G  +    LGRFCG+ +P P++A GN++ LR  SD     +GF      +A+  TE 
Sbjct: 767  VYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGF------QASHSTE- 819

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGG++    K +   +   + +++YP G+ C W I+A     + L F  F++E ++ C
Sbjct: 820  --CGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDC 877

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             YD + +F+G     A RLG++CG   P  + S G+ +LV+F SD ++T  GF   Y
Sbjct: 878  GYDYMELFDG-YDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 933



 Score =  157 bits (397), Expect = 2e-38
 Identities = 87/270 (32%), Positives = 130/270 (48%), Gaps = 34/270 (12%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG +T  +G + S G+P  YPPNK CIW +  P    +SL F  F+ E +  C+YD +E
Sbjct: 551  CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 610

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY---------- 640
            V +G     +  G+FCG+ +P  + +  N + +   SD     +GF   +          
Sbjct: 611  VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD 670

Query: 641  --------------------SGRATSGTEHQF----CGGRLEKAQGTLTTPNWPESDYPP 748
                                SG      +H      C  ++  + GT+T+PNWP+  YP 
Sbjct: 671  NGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPDK-YPS 729

Query: 749  GISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG 928
               C+W I + P   + LTF + D+E    C YD + V++G  S  A  LG+FCG K P 
Sbjct: 730  KKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDSK-APVLGRFCGSKKPE 788

Query: 929  PISSEGNELLVQFVSDLSVTADGFSASYRT 1018
            P+ + GN + ++F SD SV   GF AS+ T
Sbjct: 789  PVLATGNRMFLRFYSDNSVQRKGFQASHST 818



 Score =  130 bits (327), Expect = 3e-30
 Identities = 73/234 (31%), Positives = 115/234 (49%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G  +S  +PN Y  +  C+W I+V   + + L+F   DL     C YD +E
Sbjct: 324  CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVE 383

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G        GRFCG   P P+V+  +++ +   S     G+GF   Y          
Sbjct: 384  VRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-------- 435

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG ++K  G + +PN+P+ DY P   C W I       + LTF  F++E    C YD
Sbjct: 436  -ICGGDVKKDNGHIQSPNYPD-DYRPSKVCVWRIQVSEGFHVGLTFQSFEIERHDSCAYD 493

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + V +G  S+ +  +G++CG + P  I S  + L ++FVSD S+   GF+ ++
Sbjct: 494  YLEVRDGH-SESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 546



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 41/124 (33%), Positives = 61/124 (49%), Gaps = 4/124 (3%)
 Frame = +2

Query: 311  CGGDVTGESG----YLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG V  E      Y  ++   N YP   +C W I   E   V L F+ F++E    C Y
Sbjct: 820  CGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 879

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATS 658
            D +E+F G  ++  RLGR+CG+  P  + + G+ V ++  SD+    +GF L Y+     
Sbjct: 880  DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 939

Query: 659  GTEH 670
             T H
Sbjct: 940  DTLH 943



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 42/122 (34%), Positives = 56/122 (45%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+ + G  ++P +P   Y   + C W I   P + I L F   DL     C YD V
Sbjct: 324  CGETLQDSTGNFSSPEYPNG-YSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYV 382

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G       R G+FCG K P PI S  + L V+F S  +    GF A Y  +  G  
Sbjct: 383  EVRDGFWRKAPLR-GRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDV 441

Query: 1037 EK 1042
            +K
Sbjct: 442  KK 443


>ref|XP_001788250.1| PREDICTED: bone morphogenetic protein 1-like, partial [Bos taurus].
          Length = 1051

 Score =  167 bits (423), Expect = 2e-41
 Identities = 89/237 (37%), Positives = 137/237 (57%), Gaps = 2/237 (0%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPES-QTVSLS-FRVFDLELHPSCRYD 481
            +CGGDV  ++G++ S  +P+ Y P+K C+W I V E    +S+  F+ F++E H SC YD
Sbjct: 384  ICGGDVKKDNGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVLSIKKFQSFEIERHDSCAYD 443

Query: 482  ALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSG 661
             LEV  G   S   +GR+CG  +P  + +  +++ L+  SD      GF + +   A   
Sbjct: 444  YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKAA--- 500

Query: 662  TEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
                 CGG L K  G++T+P WP+ +YPP  +C W ++AP    ISL F  F+ E +  C
Sbjct: 501  -----CGGFLTKLNGSITSPGWPK-EYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVC 554

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
            +YD V V +G ++ D+K  GKFCG + P  I+S+ N + V+F SD +V+  GF A +
Sbjct: 555  KYDFVEVRSG-LTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 610



 Score =  157 bits (397), Expect = 2e-38
 Identities = 87/270 (32%), Positives = 130/270 (48%), Gaps = 34/270 (12%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG +T  +G + S G+P  YPPNK CIW +  P    +SL F  F+ E +  C+YD +E
Sbjct: 501  CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 560

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY---------- 640
            V +G     +  G+FCG+ +P  + +  N + +   SD     +GF   +          
Sbjct: 561  VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD 620

Query: 641  --------------------SGRATSGTEHQF----CGGRLEKAQGTLTTPNWPESDYPP 748
                                SG      +H      C  ++  + GT+T+PNWP+  YP 
Sbjct: 621  NGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPDK-YPS 679

Query: 749  GISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG 928
               C+W I + P   + LTF + D+E    C YD + V++G  S  A  LG+FCG K P 
Sbjct: 680  KKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDSK-APVLGRFCGSKKPE 738

Query: 929  PISSEGNELLVQFVSDLSVTADGFSASYRT 1018
            P+ + GN + ++F SD SV   GF AS+ T
Sbjct: 739  PVLATGNRMFLRFYSDNSVQRKGFQASHST 768



 Score =  140 bits (352), Expect = 4e-33
 Identities = 73/204 (35%), Positives = 110/204 (53%), Gaps = 3/204 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   VT  SG + S  +P+ YP  KEC W I+      V L+F   D+E  P C YD LE
Sbjct: 657  CDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 716

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V+ G  +    LGRFCG+ +P P++A GN++ LR  SD     +GF      +A+  TE 
Sbjct: 717  VYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGF------QASHSTE- 769

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGG++    K +   +   + +++YP G+ C W I+A     + L F  F++E ++ C
Sbjct: 770  --CGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDC 827

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCG 913
             YD + +F+G     A RLG++CG
Sbjct: 828  GYDYMELFDG-YDSTAPRLGRYCG 850



 Score =  124 bits (312), Expect = 2e-28
 Identities = 73/236 (30%), Positives = 118/236 (50%), Gaps = 2/236 (0%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G  +S  +PN Y  +  C+W I+V   + + L+F   DL     C YD +E
Sbjct: 272  CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVE 331

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G        GRFCG   P P+V+  +++ +   S     G+GF   Y          
Sbjct: 332  VRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-------- 383

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHI-IAPPDQVISL-TFGKFDLEPDSYCR 844
              CGG ++K  G + +PN+P+ DY P   C W I ++    V+S+  F  F++E    C 
Sbjct: 384  -ICGGDVKKDNGHIQSPNYPD-DYRPSKVCVWRIQVSEGFHVLSIKKFQSFEIERHDSCA 441

Query: 845  YDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
            YD + V +G  S+ +  +G++CG + P  I S  + L ++FVSD S+   GF+ ++
Sbjct: 442  YDYLEVRDGH-SESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 496



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 42/122 (34%), Positives = 56/122 (45%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+ + G  ++P +P   Y   + C W I   P + I L F   DL     C YD V
Sbjct: 272  CGETLQDSTGNFSSPEYPNG-YSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYV 330

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G       R G+FCG K P PI S  + L V+F S  +    GF A Y  +  G  
Sbjct: 331  EVRDGFWRKAPLR-GRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDV 389

Query: 1037 EK 1042
            +K
Sbjct: 390  KK 391



 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 4/82 (4%)
 Frame = +2

Query: 311  CGGDVTGESG----YLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG V  E      Y  ++   N YP   +C W I   E   V L F+ F++E    C Y
Sbjct: 770  CGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 829

Query: 479  DALEVFAGSGTSGQRLGRFCGT 544
            D +E+F G  ++  RLGR+CG+
Sbjct: 830  DYMELFDGYDSTAPRLGRYCGS 851


>ref|XP_002698454.1| PREDICTED: tolloid-like 2-like [Bos taurus].
          Length = 1020

 Score =  166 bits (419), Expect = 7e-41
 Identities = 91/268 (33%), Positives = 135/268 (50%), Gaps = 34/268 (12%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG++  ++G + S  +P+ Y P+KEC+W ITV E   V L+F+ F++E H SC YD LE
Sbjct: 469  CGGEINKDAGQIQSPNYPDDYRPSKECVWRITVSEGYHVGLTFQAFEIERHDSCAYDYLE 528

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLL----------W- 637
            +  G       +G FCG  +P  + +  N++ ++  SD      GF            W 
Sbjct: 529  IRDGFTEDSALIGHFCGYEKPDDVKSSSNRMWMKFVSDGSINKAGFAANFFKEVDECSWP 588

Query: 638  -----------------------YSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPP 748
                                   Y   A        CGG + K  GT+T+P WP+ +YP 
Sbjct: 589  DHGGCEQRCMNTLGSYKCMCDPGYELAADKKACEVACGGFITKLNGTITSPGWPK-EYPT 647

Query: 749  GISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG 928
              +C W ++AP    ISL F  F+LE +  C+YD V V +G +S DA+  GKFCG + P 
Sbjct: 648  NKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSG-LSPDARLHGKFCGSETPE 706

Query: 929  PISSEGNELLVQFVSDLSVTADGFSASY 1012
             I+S+ N + V+F SD +V+  GF A +
Sbjct: 707  VITSQSNNMRVEFKSDNTVSKRGFRAHF 734



 Score =  155 bits (393), Expect = 7e-38
 Identities = 83/270 (30%), Positives = 129/270 (47%), Gaps = 34/270 (12%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG +T  +G + S G+P  YP NK C+W +  P    +SL F VF+LE +  C+YD +E
Sbjct: 625  CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 684

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY------SGRA 652
            V +G     +  G+FCG+  P  + +  N + +   SD     RGF   +        + 
Sbjct: 685  VRSGLSPDARLHGKFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD 744

Query: 653  TSGTEHQF----------------------------CGGRLEKAQGTLTTPNWPESDYPP 748
              G +H+                             C  ++   +G+L +PNWP+  YP 
Sbjct: 745  NGGCQHECVNTFGSYLCRCRNGYRLHENGQDCKEAGCVHKISSTEGSLVSPNWPDK-YPS 803

Query: 749  GISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG 928
               C+W I +     + LTF +F++E    C YD + +++G  S  A  LG+FCG K P 
Sbjct: 804  RRECTWTISSTAGHRVKLTFNEFEIEQHQECAYDHLELYDGPDSQ-APILGRFCGSKKPD 862

Query: 929  PISSEGNELLVQFVSDLSVTADGFSASYRT 1018
            P+ + G+ L ++F SD SV   GF A + T
Sbjct: 863  PVVASGSSLFLRFYSDASVQRRGFQAVHST 892



 Score =  149 bits (375), Expect = 9e-36
 Identities = 82/237 (34%), Positives = 124/237 (52%), Gaps = 3/237 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   ++   G L S  +P+ YP  +EC WTI+      V L+F  F++E H  C YD LE
Sbjct: 781  CVHKISSTEGSLVSPNWPDKYPSRRECTWTISSTAGHRVKLTFNEFEIEQHQECAYDHLE 840

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            ++ G  +    LGRFCG+ +P P+VA G+ + LR  SD     RGF      +A   TE 
Sbjct: 841  LYDGPDSQAPILGRFCGSKKPDPVVASGSSLFLRFYSDASVQRRGF------QAVHSTE- 893

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGGRL+   + +   +   + +++YP    C W I+A     + L F  F++E ++ C
Sbjct: 894  --CGGRLKAEVQTKELYSHAQFGDNNYPSQARCDWVIVAEDGYGVELIFRTFEVEEEADC 951

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             YD +  F+G     A RLG+FCG      I S G+ L+++F +D ++   GF A Y
Sbjct: 952  GYDYMEAFDG-YDSTAPRLGRFCGSGPLEEIYSAGDSLMIRFHTDDTINKKGFHARY 1007



 Score =  142 bits (357), Expect = 1e-33
 Identities = 76/234 (32%), Positives = 115/234 (49%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +    G  ++ GFPN YP    C+W I+V   + + L+F   DL     C YD +E
Sbjct: 356  CGETLQDTMGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 415

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G       LGRFCG   P PL +  +++ +   S     G+GF   Y          
Sbjct: 416  VRDGYWRKAPLLGRFCGDKVPEPLTSTDSRLWVEFRSSSNILGKGFFAVYEAT------- 468

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG + K  G + +PN+P+ DY P   C W I       + LTF  F++E    C YD
Sbjct: 469  --CGGEINKDAGQIQSPNYPD-DYRPSKECVWRITVSEGYHVGLTFQAFEIERHDSCAYD 525

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + + +G  ++D+  +G FCG + P  + S  N + ++FVSD S+   GF+A++
Sbjct: 526  YLEIRDG-FTEDSALIGHFCGYEKPDDVKSSSNRMWMKFVSDGSINKAGFAANF 578



 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 45/126 (35%), Positives = 57/126 (45%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+   G  + P +P   YP    C W I   P + I L F   DL     C YD V
Sbjct: 356  CGETLQDTMGNFSAPGFPNG-YPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 414

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G     A  LG+FCGDK P P++S  + L V+F S  ++   GF A Y     G  
Sbjct: 415  EVRDGYWRK-APLLGRFCGDKVPEPLTSTDSRLWVEFRSSSNILGKGFFAVYEATCGGEI 473

Query: 1037 EKAPAQ 1054
             K   Q
Sbjct: 474  NKDAGQ 479



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
 Frame = +2

Query: 311  CGG----DVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG    +V  +  Y  ++   N YP    C W I   +   V L FR F++E    C Y
Sbjct: 894  CGGRLKAEVQTKELYSHAQFGDNNYPSQARCDWVIVAEDGYGVELIFRTFEVEEEADCGY 953

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYS 643
            D +E F G  ++  RLGRFCG+     + + G+ + +R  +D+    +GF   Y+
Sbjct: 954  DYMEAFDGYDSTAPRLGRFCGSGPLEEIYSAGDSLMIRFHTDDTINKKGFHARYT 1008


>ref|XP_869787.2| PREDICTED: tolloid-like 2-like isoform 2 [Bos taurus].
          Length = 1020

 Score =  166 bits (419), Expect = 7e-41
 Identities = 91/268 (33%), Positives = 135/268 (50%), Gaps = 34/268 (12%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG++  ++G + S  +P+ Y P+KEC+W ITV E   V L+F+ F++E H SC YD LE
Sbjct: 469  CGGEINKDAGQIQSPNYPDDYRPSKECVWRITVSEGYHVGLTFQAFEIERHDSCAYDYLE 528

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLL----------W- 637
            +  G       +G FCG  +P  + +  N++ ++  SD      GF            W 
Sbjct: 529  IRDGFTEDSALIGHFCGYEKPDDVKSSSNRMWMKFVSDGSINKAGFAANFFKEVDECSWP 588

Query: 638  -----------------------YSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPP 748
                                   Y   A        CGG + K  GT+T+P WP+ +YP 
Sbjct: 589  DHGGCEQRCMNTLGSYKCMCDPGYELAADKKACEVACGGFITKLNGTITSPGWPK-EYPT 647

Query: 749  GISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG 928
              +C W ++AP    ISL F  F+LE +  C+YD V V +G +S DA+  GKFCG + P 
Sbjct: 648  NKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSG-LSPDARLHGKFCGSETPE 706

Query: 929  PISSEGNELLVQFVSDLSVTADGFSASY 1012
             I+S+ N + V+F SD +V+  GF A +
Sbjct: 707  VITSQSNNMRVEFKSDNTVSKRGFRAHF 734



 Score =  155 bits (393), Expect = 7e-38
 Identities = 83/270 (30%), Positives = 129/270 (47%), Gaps = 34/270 (12%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG +T  +G + S G+P  YP NK C+W +  P    +SL F VF+LE +  C+YD +E
Sbjct: 625  CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 684

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY------SGRA 652
            V +G     +  G+FCG+  P  + +  N + +   SD     RGF   +        + 
Sbjct: 685  VRSGLSPDARLHGKFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD 744

Query: 653  TSGTEHQF----------------------------CGGRLEKAQGTLTTPNWPESDYPP 748
              G +H+                             C  ++   +G+L +PNWP+  YP 
Sbjct: 745  NGGCQHECVNTFGSYLCRCRNGYRLHENGQDCKEAGCVHKISSTEGSLVSPNWPDK-YPS 803

Query: 749  GISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG 928
               C+W I +     + LTF +F++E    C YD + +++G  S  A  LG+FCG K P 
Sbjct: 804  RRECTWTISSTAGHRVKLTFNEFEIEQHQECAYDHLELYDGPDSQ-APILGRFCGSKKPD 862

Query: 929  PISSEGNELLVQFVSDLSVTADGFSASYRT 1018
            P+ + G+ L ++F SD SV   GF A + T
Sbjct: 863  PVVASGSSLFLRFYSDASVQRRGFQAVHST 892



 Score =  149 bits (375), Expect = 9e-36
 Identities = 82/237 (34%), Positives = 124/237 (52%), Gaps = 3/237 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   ++   G L S  +P+ YP  +EC WTI+      V L+F  F++E H  C YD LE
Sbjct: 781  CVHKISSTEGSLVSPNWPDKYPSRRECTWTISSTAGHRVKLTFNEFEIEQHQECAYDHLE 840

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            ++ G  +    LGRFCG+ +P P+VA G+ + LR  SD     RGF      +A   TE 
Sbjct: 841  LYDGPDSQAPILGRFCGSKKPDPVVASGSSLFLRFYSDASVQRRGF------QAVHSTE- 893

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGGRL+   + +   +   + +++YP    C W I+A     + L F  F++E ++ C
Sbjct: 894  --CGGRLKAEVQTKELYSHAQFGDNNYPSQARCDWVIVAEDGYGVELIFRTFEVEEEADC 951

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             YD +  F+G     A RLG+FCG      I S G+ L+++F +D ++   GF A Y
Sbjct: 952  GYDYMEAFDG-YDSTAPRLGRFCGSGPLEEIYSAGDSLMIRFHTDDTINKKGFHARY 1007



 Score =  142 bits (357), Expect = 1e-33
 Identities = 76/234 (32%), Positives = 115/234 (49%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +    G  ++ GFPN YP    C+W I+V   + + L+F   DL     C YD +E
Sbjct: 356  CGETLQDTMGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 415

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G       LGRFCG   P PL +  +++ +   S     G+GF   Y          
Sbjct: 416  VRDGYWRKAPLLGRFCGDKVPEPLTSTDSRLWVEFRSSSNILGKGFFAVYEAT------- 468

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG + K  G + +PN+P+ DY P   C W I       + LTF  F++E    C YD
Sbjct: 469  --CGGEINKDAGQIQSPNYPD-DYRPSKECVWRITVSEGYHVGLTFQAFEIERHDSCAYD 525

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + + +G  ++D+  +G FCG + P  + S  N + ++FVSD S+   GF+A++
Sbjct: 526  YLEIRDG-FTEDSALIGHFCGYEKPDDVKSSSNRMWMKFVSDGSINKAGFAANF 578



 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 45/126 (35%), Positives = 57/126 (45%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+   G  + P +P   YP    C W I   P + I L F   DL     C YD V
Sbjct: 356  CGETLQDTMGNFSAPGFPNG-YPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 414

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G     A  LG+FCGDK P P++S  + L V+F S  ++   GF A Y     G  
Sbjct: 415  EVRDGYWRK-APLLGRFCGDKVPEPLTSTDSRLWVEFRSSSNILGKGFFAVYEATCGGEI 473

Query: 1037 EKAPAQ 1054
             K   Q
Sbjct: 474  NKDAGQ 479



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
 Frame = +2

Query: 311  CGG----DVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG    +V  +  Y  ++   N YP    C W I   +   V L FR F++E    C Y
Sbjct: 894  CGGRLKAEVQTKELYSHAQFGDNNYPSQARCDWVIVAEDGYGVELIFRTFEVEEEADCGY 953

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYS 643
            D +E F G  ++  RLGRFCG+     + + G+ + +R  +D+    +GF   Y+
Sbjct: 954  DYMEAFDGYDSTAPRLGRFCGSGPLEEIYSAGDSLMIRFHTDDTINKKGFHARYT 1008


>ref|NP_001180043.1| tolloid-like 1 [Bos taurus].
          Length = 1013

 Score =  163 bits (413), Expect = 3e-40
 Identities = 91/269 (33%), Positives = 134/269 (49%), Gaps = 34/269 (12%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGG++    G + S  +P+ Y P KEC+W I V E   V L F+ F++E H +C YD L
Sbjct: 461  ICGGEIHKNEGQIQSPNYPDDYRPMKECVWKIAVSEDCYVGLIFQAFEIERHDNCAYDYL 520

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGF------------- 628
            EV  G+  S   +GRFCG  +P  + +  N + ++  SD      GF             
Sbjct: 521  EVRDGTNESSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAK 580

Query: 629  -------------LLWYSGRATSGTE--------HQFCGGRLEKAQGTLTTPNWPESDYP 745
                         L  Y      G E           CGG L K  GT+TTP WP+ +YP
Sbjct: 581  PDRGGCEQHCLNTLGSYQCACEPGYELGPDRRTCEAACGGLLTKLNGTITTPGWPK-EYP 639

Query: 746  PGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAP 925
            P   C W ++AP    IS+ F  F+LE +  C+YD V +++G +S ++K  GK+CG + P
Sbjct: 640  PNKHCIWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSG-LSSESKLHGKYCGAEVP 698

Query: 926  GPISSEGNELLVQFVSDLSVTADGFSASY 1012
              I+S  N + ++F SD +V+  GF A +
Sbjct: 699  EVITSHFNNMRIEFKSDNTVSKKGFKAHF 727



 Score =  151 bits (381), Expect = 2e-36
 Identities = 82/240 (34%), Positives = 126/240 (52%), Gaps = 3/240 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   +   SG++ S  +P+ YP  KEC W I+      V L+F  F++E H  C YD LE
Sbjct: 774  CEQKIHSPSGFITSPNWPDKYPSRKECTWEISATPGHRVKLAFTEFEIEQHQECAYDHLE 833

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            VF G       LGR CG   P PLVA GN + +R  SD     +GF      +A   TE 
Sbjct: 834  VFDGETEKSPVLGRLCGNKIPEPLVATGNNMFVRFVSDASVQRKGF------QAAHSTE- 886

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGGRL+   K +   +   + +++YP  + C W +++     + L+F  F++E ++ C
Sbjct: 887  --CGGRLKVESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQIFEVEEEADC 944

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTL 1021
             YD V +F+G +   A  LG+FCG   P  I S G+ +L+ F +D +++  GF   Y+++
Sbjct: 945  GYDYVELFDG-LDSTAVGLGRFCGSGPPEEIYSIGDTVLIHFHTDDTISKKGFHIRYKSI 1003



 Score =  141 bits (356), Expect = 1e-33
 Identities = 79/234 (33%), Positives = 116/234 (49%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G L+S GFPN YP    CIW ++V   + + L+F   DL     C YD +E
Sbjct: 349  CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G       LGRFCG   P  L +  +++ +   S     G+GF   Y          
Sbjct: 409  VRDGYWRKSPLLGRFCGDKLPEVLTSTESRMWIEFRSSSNWVGKGFAAIYEA-------- 460

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG + K +G + +PN+P+ DY P   C W I    D  + L F  F++E    C YD
Sbjct: 461  -ICGGEIHKNEGQIQSPNYPD-DYRPMKECVWKIAVSEDCYVGLIFQAFEIERHDNCAYD 518

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + V +G  ++ +  +G+FCG   P  I S  N L ++FVSD +V   GF+A++
Sbjct: 519  YLEVRDG-TNESSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF 571



 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 41/126 (32%), Positives = 62/126 (49%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+++ G L++P +P   YP    C W +   P + I L F   DL   S C YD +
Sbjct: 349  CGETLQESNGNLSSPGFPNG-YPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYI 407

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G     +  LG+FCGDK P  ++S  + + ++F S  +    GF+A Y  +  G  
Sbjct: 408  EVRDGYWRK-SPLLGRFCGDKLPEVLTSTESRMWIEFRSSSNWVGKGFAAIYEAICGGEI 466

Query: 1037 EKAPAQ 1054
             K   Q
Sbjct: 467  HKNEGQ 472


>ref|XP_002694354.1| PREDICTED: tolloid-like 1 [Bos taurus].
          Length = 1013

 Score =  163 bits (413), Expect = 3e-40
 Identities = 91/269 (33%), Positives = 134/269 (49%), Gaps = 34/269 (12%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGG++    G + S  +P+ Y P KEC+W I V E   V L F+ F++E H +C YD L
Sbjct: 461  ICGGEIHKNEGQIQSPNYPDDYRPMKECVWKIAVSEDCYVGLIFQAFEIERHDNCAYDYL 520

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGF------------- 628
            EV  G+  S   +GRFCG  +P  + +  N + ++  SD      GF             
Sbjct: 521  EVRDGTNESSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAK 580

Query: 629  -------------LLWYSGRATSGTE--------HQFCGGRLEKAQGTLTTPNWPESDYP 745
                         L  Y      G E           CGG L K  GT+TTP WP+ +YP
Sbjct: 581  PDRGGCEQHCLNTLGSYQCACEPGYELGPDRRTCEAACGGLLTKLNGTITTPGWPK-EYP 639

Query: 746  PGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAP 925
            P   C W ++AP    IS+ F  F+LE +  C+YD V +++G +S ++K  GK+CG + P
Sbjct: 640  PNKHCIWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSG-LSSESKLHGKYCGAEVP 698

Query: 926  GPISSEGNELLVQFVSDLSVTADGFSASY 1012
              I+S  N + ++F SD +V+  GF A +
Sbjct: 699  EVITSHFNNMRIEFKSDNTVSKKGFKAHF 727



 Score =  151 bits (381), Expect = 2e-36
 Identities = 82/240 (34%), Positives = 126/240 (52%), Gaps = 3/240 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   +   SG++ S  +P+ YP  KEC W I+      V L+F  F++E H  C YD LE
Sbjct: 774  CEQKIHSPSGFITSPNWPDKYPSRKECTWEISATPGHRVKLAFTEFEIEQHQECAYDHLE 833

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            VF G       LGR CG   P PLVA GN + +R  SD     +GF      +A   TE 
Sbjct: 834  VFDGETEKSPVLGRLCGNKIPEPLVATGNNMFVRFVSDASVQRKGF------QAAHSTE- 886

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGGRL+   K +   +   + +++YP  + C W +++     + L+F  F++E ++ C
Sbjct: 887  --CGGRLKVESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQIFEVEEEADC 944

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTL 1021
             YD V +F+G +   A  LG+FCG   P  I S G+ +L+ F +D +++  GF   Y+++
Sbjct: 945  GYDYVELFDG-LDSTAVGLGRFCGSGPPEEIYSIGDTVLIHFHTDDTISKKGFHIRYKSI 1003



 Score =  141 bits (356), Expect = 1e-33
 Identities = 79/234 (33%), Positives = 116/234 (49%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G L+S GFPN YP    CIW ++V   + + L+F   DL     C YD +E
Sbjct: 349  CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G       LGRFCG   P  L +  +++ +   S     G+GF   Y          
Sbjct: 409  VRDGYWRKSPLLGRFCGDKLPEVLTSTESRMWIEFRSSSNWVGKGFAAIYEA-------- 460

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG + K +G + +PN+P+ DY P   C W I    D  + L F  F++E    C YD
Sbjct: 461  -ICGGEIHKNEGQIQSPNYPD-DYRPMKECVWKIAVSEDCYVGLIFQAFEIERHDNCAYD 518

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + V +G  ++ +  +G+FCG   P  I S  N L ++FVSD +V   GF+A++
Sbjct: 519  YLEVRDG-TNESSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF 571



 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 41/126 (32%), Positives = 62/126 (49%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+++ G L++P +P   YP    C W +   P + I L F   DL   S C YD +
Sbjct: 349  CGETLQESNGNLSSPGFPNG-YPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYI 407

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G     +  LG+FCGDK P  ++S  + + ++F S  +    GF+A Y  +  G  
Sbjct: 408  EVRDGYWRK-SPLLGRFCGDKLPEVLTSTESRMWIEFRSSSNWVGKGFAAIYEAICGGEI 466

Query: 1037 EKAPAQ 1054
             K   Q
Sbjct: 467  HKNEGQ 472


>ref|XP_002686427.1| PREDICTED: CUB domain containing protein 2-like [Bos taurus].
          Length = 622

 Score =  157 bits (396), Expect = 3e-38
 Identities = 90/239 (37%), Positives = 119/239 (49%), Gaps = 1/239 (0%)
 Frame = +2

Query: 299  PVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            P   CGG ++  SG  +S  FP+LYP N EC W I V E  +V L+F  FDLE H +C +
Sbjct: 108  PGVKCGGVLSAPSGNFSSPNFPSLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCGF 167

Query: 479  DALEVFAG-SGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRAT 655
            D LE++ G SG  G  LGRFCG   P P  +  + +++   SD+    RGF   Y     
Sbjct: 168  DFLEIYNGASGDQGNLLGRFCGRVPPPPFTSSWHVMSVVFHSDKHVASRGFSAAY----- 222

Query: 656  SGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDS 835
               +   CGG L    G L +P +P ++YP  + C W I A     I L F  F +E   
Sbjct: 223  ---QKDVCGGVLTGLSGVLASPEYP-NNYPNNVECRWVIRAAGPATIKLVFVDFQVEGSE 278

Query: 836  YCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             C YD V+V  G       R   +CG   P  + S G+EL V F SD ++   GF A Y
Sbjct: 279  QCTYDYVAVLGG---PGPAREHHYCGSARPPTLVSLGHELQVVFKSDFNIGGRGFKAYY 334



 Score =  145 bits (365), Expect = 1e-34
 Identities = 89/240 (37%), Positives = 126/240 (52%), Gaps = 5/240 (2%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGG +TG SG LAS  +PN YP N EC W I      T+ L F  F +E    C YD +
Sbjct: 226  VCGGVLTGLSGVLASPEYPNNYPNNVECRWVIRAAGPATIKLVFVDFQVEGSEQCTYDYV 285

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY-SGRATSGT 664
             V  G G + +    +CG+ RP  LV+ G+++ +   SD   GGRGF  +Y SG      
Sbjct: 286  AVLGGPGPAREH--HYCGSARPPTLVSLGHELQVVFKSDFNIGGRGFKAYYFSGE----- 338

Query: 665  EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLE-PDSY- 838
                C       +G  ++P +P S YP  I C W I  PP   + + F   +LE P+S  
Sbjct: 339  ----CQEVYTAVRGNFSSPQYPSS-YPNNIRCHWTIRLPPGYRVKVFFLDLELEEPNSLT 393

Query: 839  --CRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
              C +D ++ F+GA S++A  LG +CG   P P++S  N+LL+   +D S T  GFS +Y
Sbjct: 394  RTCDFDHLAAFDGA-SEEAPLLGTWCGHHLPPPVTSSHNQLLIVLHTDRSTTHRGFSVAY 452



 Score = 90.5 bits (223), Expect = 4e-18
 Identities = 46/113 (40%), Positives = 62/113 (54%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CGG L    G  ++PN+P S YP    CSW I+      + LTF  FDLE    C +D +
Sbjct: 112  CGGVLSAPSGNFSSPNFP-SLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCGFDFL 170

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYR 1015
             ++NGA  D    LG+FCG   P P +S  + + V F SD  V + GFSA+Y+
Sbjct: 171  EIYNGASGDQGNLLGRFCGRVPPPPFTSSWHVMSVVFHSDKHVASRGFSAAYQ 223



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLE----LHPSCRY 478
           C    T   G  +S  +P+ YP N  C WTI +P    V + F   +LE    L  +C +
Sbjct: 339 CQEVYTAVRGNFSSPQYPSSYPNNIRCHWTIRLPPGYRVKVFFLDLELEEPNSLTRTCDF 398

Query: 479 DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSG 646
           D L  F G+      LG +CG   P P+ +  NQ+ + + +D  T  RGF + Y G
Sbjct: 399 DHLAAFDGASEEAPLLGTWCGHHLPPPVTSSHNQLLIVLHTDRSTTHRGFSVAYIG 454


>ref|XP_594473.4| PREDICTED: CUB domain containing protein 2 [Bos taurus].
          Length = 649

 Score =  154 bits (389), Expect = 2e-37
 Identities = 88/235 (37%), Positives = 117/235 (49%), Gaps = 1/235 (0%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG ++  SG  +S  FP+LYP N EC W I V E  +V L+F  FDLE H +C +D LE
Sbjct: 139  CGGVLSAPSGNFSSPNFPSLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCGFDFLE 198

Query: 491  VFAG-SGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTE 667
            ++ G SG  G  LGRFCG   P P  +  + +++   SD+    RGF   Y        +
Sbjct: 199  IYNGASGDQGNLLGRFCGRVPPPPFTSSWHVMSVVFHSDKHVASRGFSAAY--------Q 250

Query: 668  HQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRY 847
               CGG L    G L +P +P ++YP  + C W I A     I L F  F +E    C Y
Sbjct: 251  KDVCGGVLTGLSGVLASPEYP-NNYPNNVECRWVIRAAGPATIKLVFVDFQVEGSEQCTY 309

Query: 848  DSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
            D V+V  G       R   +CG   P  + S  +EL V F SD ++   GF A Y
Sbjct: 310  DYVAVLGG---PGPAREHHYCGSARPPTLVSLSHELQVVFKSDFNIGGRGFKAYY 361



 Score =  142 bits (359), Expect = 6e-34
 Identities = 89/240 (37%), Positives = 125/240 (52%), Gaps = 5/240 (2%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGG +TG SG LAS  +PN YP N EC W I      T+ L F  F +E    C YD +
Sbjct: 253  VCGGVLTGLSGVLASPEYPNNYPNNVECRWVIRAAGPATIKLVFVDFQVEGSEQCTYDYV 312

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY-SGRATSGT 664
             V  G G +  R   +CG+ RP  LV+  +++ +   SD   GGRGF  +Y SG      
Sbjct: 313  AVLGGPGPA--REHHYCGSARPPTLVSLSHELQVVFKSDFNIGGRGFKAYYFSGE----- 365

Query: 665  EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDL-EPDSY- 838
                C       +G  ++P +P S YP  I C W I  PP   + + F   +L EP+S  
Sbjct: 366  ----CQEVYTAVRGNFSSPQYP-SSYPNNIRCHWTIRLPPGYRVKVFFLDLELEEPNSLT 420

Query: 839  --CRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
              C +D ++ F+GA S++A  LG +CG   P P++S  N+LL+   +D S T  GFS +Y
Sbjct: 421  RTCDFDHLAAFDGA-SEEAPLLGTWCGHHLPPPVTSSHNQLLIVLHTDRSTTHRGFSVAY 479



 Score = 90.5 bits (223), Expect = 4e-18
 Identities = 46/113 (40%), Positives = 62/113 (54%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CGG L    G  ++PN+P S YP    CSW I+      + LTF  FDLE    C +D +
Sbjct: 139  CGGVLSAPSGNFSSPNFP-SLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCGFDFL 197

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYR 1015
             ++NGA  D    LG+FCG   P P +S  + + V F SD  V + GFSA+Y+
Sbjct: 198  EIYNGASGDQGNLLGRFCGRVPPPPFTSSWHVMSVVFHSDKHVASRGFSAAYQ 250



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLE----LHPSCRY 478
           C    T   G  +S  +P+ YP N  C WTI +P    V + F   +LE    L  +C +
Sbjct: 366 CQEVYTAVRGNFSSPQYPSSYPNNIRCHWTIRLPPGYRVKVFFLDLELEEPNSLTRTCDF 425

Query: 479 DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSG 646
           D L  F G+      LG +CG   P P+ +  NQ+ + + +D  T  RGF + Y G
Sbjct: 426 DHLAAFDGASEEAPLLGTWCGHHLPPPVTSSHNQLLIVLHTDRSTTHRGFSVAYIG 481


  Database: RefSeq49_BP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 17,681,374
  Number of sequences in database:  33,088
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33088
Number of Hits to DB: 66,391,451
Number of extensions: 2280720
Number of successful extensions: 13278
Number of sequences better than 1.0e-05: 68
Number of HSP's gapped: 12707
Number of HSP's successfully gapped: 278
Length of query: 520
Length of database: 17,681,374
Length adjustment: 107
Effective length of query: 413
Effective length of database: 14,140,958
Effective search space: 5840215654
Effective search space used: 5840215654
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-002572
         (1561 letters)

Database: RefSeq49_CP.fasta 
           33,336 sequences; 18,874,504 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|XP_859401.1| PREDICTED: similar to Procollagen C-proteinase ...   749   0.0  
Alignment   gi|XP_546953.2| PREDICTED: similar to Procollagen C-proteinase ...   735   0.0  
Alignment   gi|XP_852496.1| PREDICTED: similar to Procollagen C-endopeptida...   309   5e-84
Alignment   gi|XP_534296.1| PREDICTED: similar to Procollagen C-endopeptida...   309   5e-84
Alignment   gi|XP_865815.1| PREDICTED: similar to Procollagen C-endopeptida...   171   2e-42
Alignment   gi|XP_539791.2| PREDICTED: similar to tolloid-like 1 [Canis fam...   169   7e-42
Alignment   gi|XP_543945.2| PREDICTED: similar to tolloid-like 2 [Canis fam...   169   9e-42
Alignment   gi|XP_546699.2| PREDICTED: similar to Dorsal-ventral patterning...   164   2e-40
Alignment   gi|XP_851362.1| PREDICTED: similar to Bone morphogenetic protei...   163   5e-40
Alignment   gi|XP_535142.2| PREDICTED: similar to Neuropilin-1 precursor (V...   151   1e-36

>ref|XP_859401.1| PREDICTED: similar to Procollagen C-proteinase enhancer protein
            precursor (PCPE) (Type I procollagen COOH-terminal
            proteinase enhancer) (Type 1 procollagen C-proteinase
            enhancer protein) isoform 3 [Canis familiaris].
          Length = 458

 Score =  749 bits (1933), Expect = 0.0
 Identities = 370/453 (81%), Positives = 382/453 (84%)
 Frame = +2

Query: 203  MLPAATASXXXXXXXXXXXXXFAQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPN 382
            MLPAATAS             F QGQTPNYTRPVFLCGGDVTGESGY+ASEGFPNLYPPN
Sbjct: 1    MLPAATASLLGPLLTAWALLPFTQGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPN 60

Query: 383  KECIWTITVPESQTVSLSFRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPL 562
            KECIWTITVPE QTVSLSFRVFDLELHP+CRYDALEVFAGSGTSGQRLGRFCGTFRPAPL
Sbjct: 61   KECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPL 120

Query: 563  VAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDY 742
            VAPGNQVTLRMT+DEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDY
Sbjct: 121  VAPGNQVTLRMTADEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDY 180

Query: 743  PPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKA 922
            PPGISCSWHIIAPPDQVISLTFGKFDLEPD+YCRYDSVSVFNGAVSDDAKRLGKFCGD A
Sbjct: 181  PPGISCSWHIIAPPDQVISLTFGKFDLEPDTYCRYDSVSVFNGAVSDDAKRLGKFCGDTA 240

Query: 923  PGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGATEKAPAQSPGEDARXXXXXXXXX 1102
            PGPISSEGNELLVQFVSDLSVTADGFSASY+TLPRGA  +  A+SPGEDAR         
Sbjct: 241  PGPISSEGNELLVQFVSDLSVTADGFSASYKTLPRGAAAEGQARSPGEDAR--------- 291

Query: 1103 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSDGPSVPCPKQCRRTGTLQSNFCNSNLVV 1282
                                            + P+V CPKQCRRTGTLQSNFC+S+LVV
Sbjct: 292  ---SGASLPKPGPPPVEKPKASSEAQATPEAPNVPNVSCPKQCRRTGTLQSNFCSSSLVV 348

Query: 1283 TATVKSMVRGPGEGLTVTVSLIGVYKTGGLDLPSPPTDTSLKFYAPCKQCPPMKKGTSYL 1462
            TATVKSMVRGPGEGLTVTVSLIG YKTGGLDLPSP TDT LKFY PCKQCPPMKKG SYL
Sbjct: 349  TATVKSMVRGPGEGLTVTVSLIGAYKTGGLDLPSPITDTPLKFYVPCKQCPPMKKGASYL 408

Query: 1463 MMGQVDENRGPILPPESFVVLYRPNQGQILTKL 1561
            MMGQV+ENRGPILP ESFVVLYRPNQ QILT L
Sbjct: 409  MMGQVEENRGPILPAESFVVLYRPNQDQILTNL 441


>ref|XP_546953.2| PREDICTED: similar to Procollagen C-proteinase enhancer protein
            precursor (PCPE) (Type I procollagen COOH-terminal
            proteinase enhancer) (Type 1 procollagen C-proteinase
            enhancer protein) isoform 2 [Canis familiaris].
          Length = 483

 Score =  735 bits (1897), Expect = 0.0
 Identities = 370/478 (77%), Positives = 382/478 (79%), Gaps = 25/478 (5%)
 Frame = +2

Query: 203  MLPAATASXXXXXXXXXXXXXFAQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPN 382
            MLPAATAS             F QGQTPNYTRPVFLCGGDVTGESGY+ASEGFPNLYPPN
Sbjct: 1    MLPAATASLLGPLLTAWALLPFTQGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPN 60

Query: 383  KECIWTITVPESQTVSLSFRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPL 562
            KECIWTITVPE QTVSLSFRVFDLELHP+CRYDALEVFAGSGTSGQRLGRFCGTFRPAPL
Sbjct: 61   KECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPL 120

Query: 563  VAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGT-------------------------E 667
            VAPGNQVTLRMT+DEGTGGRGFLLWYSGRATSGT                         E
Sbjct: 121  VAPGNQVTLRMTADEGTGGRGFLLWYSGRATSGTGPPPGARRKWVTDPRVEWAAWGYWDE 180

Query: 668  HQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRY 847
            HQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPD+YCRY
Sbjct: 181  HQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDTYCRY 240

Query: 848  DSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPR 1027
            DSVSVFNGAVSDDAKRLGKFCGD APGPISSEGNELLVQFVSDLSVTADGFSASY+TLPR
Sbjct: 241  DSVSVFNGAVSDDAKRLGKFCGDTAPGPISSEGNELLVQFVSDLSVTADGFSASYKTLPR 300

Query: 1028 GATEKAPAQSPGEDARXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSDGP 1207
            GA  +  A+SPGEDAR                                         + P
Sbjct: 301  GAAAEGQARSPGEDAR------------SGASLPKPGPPPVEKPKASSEAQATPEAPNVP 348

Query: 1208 SVPCPKQCRRTGTLQSNFCNSNLVVTATVKSMVRGPGEGLTVTVSLIGVYKTGGLDLPSP 1387
            +V CPKQCRRTGTLQSNFC+S+LVVTATVKSMVRGPGEGLTVTVSLIG YKTGGLDLPSP
Sbjct: 349  NVSCPKQCRRTGTLQSNFCSSSLVVTATVKSMVRGPGEGLTVTVSLIGAYKTGGLDLPSP 408

Query: 1388 PTDTSLKFYAPCKQCPPMKKGTSYLMMGQVDENRGPILPPESFVVLYRPNQGQILTKL 1561
             TDT LKFY PCKQCPPMKKG SYLMMGQV+ENRGPILP ESFVVLYRPNQ QILT L
Sbjct: 409  ITDTPLKFYVPCKQCPPMKKGASYLMMGQVEENRGPILPAESFVVLYRPNQDQILTNL 466


>ref|XP_852496.1| PREDICTED: similar to Procollagen C-endopeptidase enhancer 2
            precursor (Procollagen COOH-terminal proteinase enhancer
            2) isoform 2 [Canis familiaris].
          Length = 418

 Score =  309 bits (791), Expect = 5e-84
 Identities = 139/244 (56%), Positives = 179/244 (73%)
 Frame = +2

Query: 296  RPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCR 475
            RPVF CGG +TGESG++ SEGFP +YPPN +C W ITVPE + V L+FR  DLE    CR
Sbjct: 28   RPVFTCGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCR 87

Query: 476  YDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRAT 655
            YD ++V+ G  T+GQR+GRFCGTFRP  LV+ GN++ ++M SD  T G GF+  +S    
Sbjct: 88   YDFVDVYNGH-TNGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEP 146

Query: 656  SGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDS 835
            +    Q+CGGRLE+  G+  TPNWP+ DYP G++C WHI+AP +Q+I L F KFD+E D+
Sbjct: 147  NERGDQYCGGRLERPSGSFKTPNWPDRDYPAGVTCMWHIVAPKNQLIELKFEKFDVERDN 206

Query: 836  YCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYR 1015
            YCRYD V+VFNG   +DAKR+GK+CGD  P PI SE NELL+QF+SDLS+TADGF   Y+
Sbjct: 207  YCRYDFVAVFNGGEVNDAKRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHYK 266

Query: 1016 TLPR 1027
              P+
Sbjct: 267  FRPK 270



 Score = 95.9 bits (237), Expect = 9e-20
 Identities = 49/116 (42%), Positives = 75/116 (64%), Gaps = 1/116 (0%)
 Frame = +2

Query: 1217 CPKQCRRTGTLQSNFCNSNLVVTATVKSMVRGPGEGLTVTVSLIGVYKTGGLDLPSPPTD 1396
            C ++CRRTGTL+SN+C+SN V+  TV + V   G  L  TVS+I +YK G L +     +
Sbjct: 300  CQQKCRRTGTLESNYCSSNFVLAGTVITTVTRGGS-LHATVSIINIYKEGNLAIQQAGKN 358

Query: 1397 TSLKFYAPCKQCPPMKKGTSYLMMGQVDEN-RGPILPPESFVVLYRPNQGQILTKL 1561
             S K    CKQCP +++G +Y++MGQV E+ RG I+ P SF+++++    ++L  L
Sbjct: 359  MSAKVIVVCKQCPLLRRGLNYIIMGQVGEDGRGKIM-PNSFIMMFKTKNQKLLDAL 413


>ref|XP_534296.1| PREDICTED: similar to Procollagen C-endopeptidase enhancer 2
            precursor (Procollagen COOH-terminal proteinase enhancer
            2) isoform 1 [Canis familiaris].
          Length = 415

 Score =  309 bits (791), Expect = 5e-84
 Identities = 139/244 (56%), Positives = 179/244 (73%)
 Frame = +2

Query: 296  RPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCR 475
            RPVF CGG +TGESG++ SEGFP +YPPN +C W ITVPE + V L+FR  DLE    CR
Sbjct: 28   RPVFTCGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCR 87

Query: 476  YDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRAT 655
            YD ++V+ G  T+GQR+GRFCGTFRP  LV+ GN++ ++M SD  T G GF+  +S    
Sbjct: 88   YDFVDVYNGH-TNGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEP 146

Query: 656  SGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDS 835
            +    Q+CGGRLE+  G+  TPNWP+ DYP G++C WHI+AP +Q+I L F KFD+E D+
Sbjct: 147  NERGDQYCGGRLERPSGSFKTPNWPDRDYPAGVTCMWHIVAPKNQLIELKFEKFDVERDN 206

Query: 836  YCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYR 1015
            YCRYD V+VFNG   +DAKR+GK+CGD  P PI SE NELL+QF+SDLS+TADGF   Y+
Sbjct: 207  YCRYDFVAVFNGGEVNDAKRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHYK 266

Query: 1016 TLPR 1027
              P+
Sbjct: 267  FRPK 270



 Score = 95.9 bits (237), Expect = 9e-20
 Identities = 49/116 (42%), Positives = 75/116 (64%), Gaps = 1/116 (0%)
 Frame = +2

Query: 1217 CPKQCRRTGTLQSNFCNSNLVVTATVKSMVRGPGEGLTVTVSLIGVYKTGGLDLPSPPTD 1396
            C ++CRRTGTL+SN+C+SN V+  TV + V   G  L  TVS+I +YK G L +     +
Sbjct: 297  CQQKCRRTGTLESNYCSSNFVLAGTVITTVTRGGS-LHATVSIINIYKEGNLAIQQAGKN 355

Query: 1397 TSLKFYAPCKQCPPMKKGTSYLMMGQVDEN-RGPILPPESFVVLYRPNQGQILTKL 1561
             S K    CKQCP +++G +Y++MGQV E+ RG I+ P SF+++++    ++L  L
Sbjct: 356  MSAKVIVVCKQCPLLRRGLNYIIMGQVGEDGRGKIM-PNSFIMMFKTKNQKLLDAL 410


>ref|XP_865815.1| PREDICTED: similar to Procollagen C-endopeptidase enhancer 2
            precursor (Procollagen COOH-terminal proteinase enhancer
            2) isoform 4 [Canis familiaris].
          Length = 268

 Score =  171 bits (432), Expect = 2e-42
 Identities = 73/119 (61%), Positives = 93/119 (78%)
 Frame = +2

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
            Q+CGGRLE+  G+  TPNWP+ DYP G++C WHI+AP +Q+I L F KFD+E D+YCRYD
Sbjct: 5    QYCGGRLERPSGSFKTPNWPDRDYPAGVTCMWHIVAPKNQLIELKFEKFDVERDNYCRYD 64

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPR 1027
             V+VFNG   +DAKR+GK+CGD  P PI SE NELL+QF+SDLS+TADGF   Y+  P+
Sbjct: 65   FVAVFNGGEVNDAKRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHYKFRPK 123



 Score = 95.9 bits (237), Expect = 9e-20
 Identities = 49/116 (42%), Positives = 75/116 (64%), Gaps = 1/116 (0%)
 Frame = +2

Query: 1217 CPKQCRRTGTLQSNFCNSNLVVTATVKSMVRGPGEGLTVTVSLIGVYKTGGLDLPSPPTD 1396
            C ++CRRTGTL+SN+C+SN V+  TV + V   G  L  TVS+I +YK G L +     +
Sbjct: 150  CQQKCRRTGTLESNYCSSNFVLAGTVITTVTRGGS-LHATVSIINIYKEGNLAIQQAGKN 208

Query: 1397 TSLKFYAPCKQCPPMKKGTSYLMMGQVDEN-RGPILPPESFVVLYRPNQGQILTKL 1561
             S K    CKQCP +++G +Y++MGQV E+ RG I+ P SF+++++    ++L  L
Sbjct: 209  MSAKVIVVCKQCPLLRRGLNYIIMGQVGEDGRGKIM-PNSFIMMFKTKNQKLLDAL 263



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 40/115 (34%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNL-YPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
           CGG +   SG   +  +P+  YP    C+W I  P++Q + L F  FD+E    CRYD +
Sbjct: 7   CGGRLERPSGSFKTPNWPDRDYPAGVTCMWHIVAPKNQLIELKFEKFDVERDNYCRYDFV 66

Query: 488 EVF-AGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGR 649
            VF  G     +R+G++CG   PAP+V+  N++ ++  SD      GF+  Y  R
Sbjct: 67  AVFNGGEVNDAKRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHYKFR 121


>ref|XP_539791.2| PREDICTED: similar to tolloid-like 1 [Canis familiaris].
          Length = 1045

 Score =  169 bits (428), Expect = 7e-42
 Identities = 92/269 (34%), Positives = 138/269 (51%), Gaps = 34/269 (12%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGG++    G + S  +P+ Y P KEC+W ITV E   V L+F+ F++E H +C YD L
Sbjct: 493  ICGGEIRKHEGQIQSPNYPDDYRPMKECVWKITVSEDYYVGLTFQAFEIERHDNCAYDYL 552

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGF------------- 628
            EV  G+  +   +GRFCG  +P  + +  N + ++  SD      GF             
Sbjct: 553  EVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAK 612

Query: 629  -------------LLWYSGRATSGTE--------HQFCGGRLEKAQGTLTTPNWPESDYP 745
                         L  Y      G E           CGG L K  GT+TTP WP+ +YP
Sbjct: 613  PDRGGCEQRCLNTLGSYQCACEPGYELGPDKRSCEAACGGLLTKLNGTITTPGWPK-EYP 671

Query: 746  PGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAP 925
            P  +C W ++AP    IS+ F  F+LE +  C+YD V +++G +S ++K  GKFCG + P
Sbjct: 672  PNKNCVWQVVAPTQYRISMKFEFFELEGNEVCKYDYVEIWSG-LSSESKLHGKFCGAEVP 730

Query: 926  GPISSEGNELLVQFVSDLSVTADGFSASY 1012
              I+S+ N + ++F SD +V+  GF A +
Sbjct: 731  EVITSQFNNMRIEFRSDNTVSKKGFKAHF 759



 Score =  150 bits (378), Expect = 4e-36
 Identities = 81/240 (33%), Positives = 127/240 (52%), Gaps = 3/240 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   +   SG++ S  +P+ YP  KEC W I+      + L+F  F++E H  C YD LE
Sbjct: 806  CEQKIHSPSGFITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLE 865

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            VF G       LGR CG   P PL+A GN++ +R  SD     +GF      +AT  TE 
Sbjct: 866  VFDGETEKSPILGRLCGNKIPEPLLATGNKMFVRFISDASVQRKGF------QATHSTE- 918

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGGRL+   K +   +   + +++YP  + C W +++     + L+F  F++E ++ C
Sbjct: 919  --CGGRLKAELKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGFRLELSFQIFEVEEEADC 976

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTL 1021
             YD V +F+G +   A  LG+FCG   P  I S G+ +L+ F +D ++   GF   Y+++
Sbjct: 977  GYDYVELFDG-LDSTAVGLGRFCGSGPPEEIYSIGDAVLIHFHTDDTINKKGFHIRYKSI 1035



 Score =  146 bits (369), Expect = 5e-35
 Identities = 81/234 (34%), Positives = 118/234 (50%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G L+S GFPN YP    CIW ++V   + + L+F   DL     C YD +E
Sbjct: 381  CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 440

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G       LGRFCG   P  L +  +++ +   S     G+GF   Y          
Sbjct: 441  VRDGYWRKSPLLGRFCGDKLPEVLASTDSRMWIEFRSSSNWVGKGFAAAYEA-------- 492

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG + K +G + +PN+P+ DY P   C W I    D  + LTF  F++E    C YD
Sbjct: 493  -ICGGEIRKHEGQIQSPNYPD-DYRPMKECVWKITVSEDYYVGLTFQAFEIERHDNCAYD 550

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + V +G  S+++  +G+FCG   P  I S  N L ++FVSD +V   GF+A++
Sbjct: 551  YLEVRDG-TSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF 603



 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 41/126 (32%), Positives = 63/126 (50%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+++ G L++P +P   YP    C W +   P + I L F   DL   S C YD +
Sbjct: 381  CGETLQESNGNLSSPGFPNG-YPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYI 439

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G     +  LG+FCGDK P  ++S  + + ++F S  +    GF+A+Y  +  G  
Sbjct: 440  EVRDGYWRK-SPLLGRFCGDKLPEVLASTDSRMWIEFRSSSNWVGKGFAAAYEAICGGEI 498

Query: 1037 EKAPAQ 1054
             K   Q
Sbjct: 499  RKHEGQ 504



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 4/124 (3%)
 Frame = +2

Query: 311  CGGDVTGESG----YLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG +  E      Y  ++   N YP   +C W +       + LSF++F++E    C Y
Sbjct: 919  CGGRLKAELKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGFRLELSFQIFEVEEEADCGY 978

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATS 658
            D +E+F G  ++   LGRFCG+  P  + + G+ V +   +D+    +GF + Y      
Sbjct: 979  DYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDAVLIHFHTDDTINKKGFHIRYKSIRYP 1038

Query: 659  GTEH 670
             T H
Sbjct: 1039 DTMH 1042


>ref|XP_543945.2| PREDICTED: similar to tolloid-like 2 [Canis familiaris].
          Length = 1032

 Score =  169 bits (427), Expect = 9e-42
 Identities = 93/268 (34%), Positives = 136/268 (50%), Gaps = 34/268 (12%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGGD+  ++G + S  +P+ Y P+KEC+W ITV E   V L+F+ F++E H SC YD LE
Sbjct: 471  CGGDINKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 530

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLL----------W- 637
            +  G       +G FCG  +P  + +  N++ ++  SD      GF            W 
Sbjct: 531  IRDGPTEESALIGHFCGYEKPEDVKSSSNRMWMKFVSDGSINKAGFAANFFKEVDECSWP 590

Query: 638  -----------------------YSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPP 748
                                   Y   A   T    CGG + K  GT+T+P WP+ +YP 
Sbjct: 591  DHGGCEQRCVNTLGSYKCACDPGYELAADKKTCEVACGGFITKLNGTITSPGWPK-EYPT 649

Query: 749  GISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG 928
              +C W ++AP    ISL F  F+LE +  C+YD V V +G +S DA+  GKFCG + P 
Sbjct: 650  NKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSG-LSPDARLHGKFCGSEMPE 708

Query: 929  PISSEGNELLVQFVSDLSVTADGFSASY 1012
             I+S+ N + V+F SD +V+  GF A +
Sbjct: 709  VITSQSNNMRVEFKSDNTVSKRGFRAHF 736



 Score =  161 bits (407), Expect = 2e-39
 Identities = 89/270 (32%), Positives = 134/270 (49%), Gaps = 34/270 (12%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG +T  +G + S G+P  YP NK C+W +  P    +SL F VF+LE +  C+YD +E
Sbjct: 627  CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 686

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY---------- 640
            V +G     +  G+FCG+  P  + +  N + +   SD     RGF   +          
Sbjct: 687  VRSGLSPDARLHGKFCGSEMPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAED 746

Query: 641  SGRA------TSGT------------------EHQFCGGRLEKAQGTLTTPNWPESDYPP 748
            +GR       TSG+                  +   C  ++  A+GTL +PNWP+  YP 
Sbjct: 747  NGRCQHECVNTSGSYLCRCRTGYRLHDNGHDCKEAGCAHKISSAEGTLASPNWPDK-YPS 805

Query: 749  GISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG 928
               C+W+I +     + LTF +F++E    C YD + +++G  S  A  LG+FCG K P 
Sbjct: 806  RRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLELYDGPDSL-APILGRFCGSKKPD 864

Query: 929  PISSEGNELLVQFVSDLSVTADGFSASYRT 1018
            P+ + G+ L V+F SD SV   GF A + T
Sbjct: 865  PVVASGSSLFVRFYSDASVQRKGFQAVHST 894



 Score =  139 bits (351), Expect = 6e-33
 Identities = 76/234 (32%), Positives = 114/234 (48%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G  ++ GFPN YP    C+W I+V   + + L+F   DL     C YD +E
Sbjct: 358  CGETLQDTAGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 417

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G       LGRFCG   P PL +  +++ +   S     G+GF   Y          
Sbjct: 418  VRDGYWRKAPLLGRFCGDKVPEPLTSTDSRLWVEFRSSSSLLGKGFFAVYEAT------- 470

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG + K  G + +PN+P+ DY P   C W I       + LTF  F++E    C YD
Sbjct: 471  --CGGDINKDAGQIQSPNYPD-DYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 527

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + + +G   + A  +G FCG + P  + S  N + ++FVSD S+   GF+A++
Sbjct: 528  YLEIRDGPTEESA-LIGHFCGYEKPEDVKSSSNRMWMKFVSDGSINKAGFAANF 580



 Score =  128 bits (321), Expect = 2e-29
 Identities = 80/247 (32%), Positives = 125/247 (50%), Gaps = 13/247 (5%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   ++   G LAS  +P+ YP  +EC W I+      V L+F  F++E H  C YD LE
Sbjct: 783  CAHKISSAEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLE 842

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            ++ G  +    LGRFCG+ +P P+VA G+ + +R  SD     +GF      +A   TE 
Sbjct: 843  LYDGPDSLAPILGRFCGSKKPDPVVASGSSLFVRFYSDASVQRKGF------QAVHSTE- 895

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGGRL+   + +   +   + +++YP    C+W I+A       L F  F+ E ++ C
Sbjct: 896  --CGGRLKAEVQTKELYSHAQFGDNNYPSQARCAWVIVAEDGYGAELIFRIFEEEEEADC 953

Query: 842  RYDSV-------SVFNGAVSDDAKRLGKFCGDKAPGP---ISSEGNELLVQFVSDLSVTA 991
             YD +       S F+G+ +  A   GK    ++ GP   I S G+ L++QF +D ++  
Sbjct: 954  GYDYMEADDGYDSTFSGSAASAAPG-GKPWKVQSSGPLEEIYSAGDSLMIQFHTDDTINK 1012

Query: 992  DGFSASY 1012
             GF A Y
Sbjct: 1013 KGFHARY 1019



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 46/126 (36%), Positives = 57/126 (45%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+   G  + P +P   YP    C W I   P + I L F   DL     C YD V
Sbjct: 358  CGETLQDTAGNFSAPGFPNG-YPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 416

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G     A  LG+FCGDK P P++S  + L V+F S  S+   GF A Y     G  
Sbjct: 417  EVRDGYWRK-APLLGRFCGDKVPEPLTSTDSRLWVEFRSSSSLLGKGFFAVYEATCGGDI 475

Query: 1037 EKAPAQ 1054
             K   Q
Sbjct: 476  NKDAGQ 481


>ref|XP_546699.2| PREDICTED: similar to Dorsal-ventral patterning tolloid-like protein
            1 precursor (Mini fin protein) [Canis familiaris].
          Length = 657

 Score =  164 bits (415), Expect = 2e-40
 Identities = 93/239 (38%), Positives = 123/239 (51%), Gaps = 1/239 (0%)
 Frame = +2

Query: 299  PVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            P   CGG ++  SG  +S  FP LYP N EC W I V E  +V L+F  FDLE H SC +
Sbjct: 121  PGVKCGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDSCGF 180

Query: 479  DALEVFAG-SGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRAT 655
            D LEV+ G SG  G  LGRFCG   P P  +  + +++   SD+    RGF        +
Sbjct: 181  DYLEVYNGASGDKGSLLGRFCGQVPPPPFTSSWHVMSVVFHSDKHVASRGF--------S 232

Query: 656  SGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDS 835
            +G +   CGG L    G LT+P +P+ +YP  + C W I A     + L F  F LE + 
Sbjct: 233  AGYQKDVCGGVLTGLSGVLTSPEYPD-NYPNNVECHWVIRASGAATVKLVFVDFQLEGNE 291

Query: 836  YCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             C YD V+V  G+V         +CG   P  + S G+EL V F SD ++   GF A Y
Sbjct: 292  ECTYDYVAVLEGSVPAHGHH---YCGSTRPPTLVSLGHELQVIFKSDFNIGGRGFKAYY 347



 Score =  143 bits (360), Expect = 5e-34
 Identities = 92/253 (36%), Positives = 132/253 (52%), Gaps = 5/253 (1%)
 Frame = +2

Query: 269  AQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVF 448
            ++G +  Y + V  CGG +TG SG L S  +P+ YP N EC W I    + TV L F  F
Sbjct: 228  SRGFSAGYQKDV--CGGVLTGLSGVLTSPEYPDNYPNNVECHWVIRASGAATVKLVFVDF 285

Query: 449  DLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGF 628
             LE +  C YD + V  GS  +      +CG+ RP  LV+ G+++ +   SD   GGRGF
Sbjct: 286  QLEGNEECTYDYVAVLEGSVPAHGH--HYCGSTRPPTLVSLGHELQVIFKSDFNIGGRGF 343

Query: 629  LLWY-SGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLT 805
              +Y SG          C       +G  ++P +P+S YP  I C W I  PP   + + 
Sbjct: 344  KAYYFSGE---------CQEVYTAVRGNFSSPQYPDS-YPNNIHCHWTIRLPPGYRVKVF 393

Query: 806  FGKFDLE-PDSY---CRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVS 973
            F   DLE P+S    C +D +S ++GA S++A  LG +CG   P P++S  N+LL+   +
Sbjct: 394  FLDLDLEGPNSLTRTCDFDHLSAYDGA-SEEAPLLGSWCGHHLPAPVTSNQNQLLLLLHT 452

Query: 974  DLSVTADGFSASY 1012
            D S    GFS +Y
Sbjct: 453  DRSTARRGFSVAY 465



 Score = 90.1 bits (222), Expect = 5e-18
 Identities = 46/113 (40%), Positives = 60/113 (53%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CGG L    G  ++PN+P   YP    CSW I+      + LTF  FDLE    C +D +
Sbjct: 125  CGGVLSAPSGNFSSPNFPRL-YPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDSCGFDYL 183

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYR 1015
             V+NGA  D    LG+FCG   P P +S  + + V F SD  V + GFSA Y+
Sbjct: 184  EVYNGASGDKGSLLGRFCGQVPPPPFTSSWHVMSVVFHSDKHVASRGFSAGYQ 236



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 40/116 (34%), Positives = 56/116 (48%), Gaps = 4/116 (3%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLE----LHPSCRY 478
           C    T   G  +S  +P+ YP N  C WTI +P    V + F   DLE    L  +C +
Sbjct: 352 CQEVYTAVRGNFSSPQYPDSYPNNIHCHWTIRLPPGYRVKVFFLDLDLEGPNSLTRTCDF 411

Query: 479 DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSG 646
           D L  + G+      LG +CG   PAP+ +  NQ+ L + +D  T  RGF + Y G
Sbjct: 412 DHLSAYDGASEEAPLLGSWCGHHLPAPVTSNQNQLLLLLHTDRSTARRGFSVAYIG 467


>ref|XP_851362.1| PREDICTED: similar to Bone morphogenetic protein 1 precursor (BMP-1)
            (Procollagen C-proteinase) (PCP) (Mammalian tolloid
            protein) (mTld) [Canis familiaris].
          Length = 975

 Score =  163 bits (412), Expect = 5e-40
 Identities = 92/269 (34%), Positives = 140/269 (52%), Gaps = 34/269 (12%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGGDV  ++G++ S  +P+ Y P+K CIW I V E   V L+F+ F++E H SC YD L
Sbjct: 423  ICGGDVKKDNGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYL 482

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY-------SG 646
            EV  G   +   +GR+CG  +P  + +  +++ L+  SD      GF + +       S 
Sbjct: 483  EVRDGHSETSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR 542

Query: 647  RATSGTEHQF---------------------------CGGRLEKAQGTLTTPNWPESDYP 745
                G E +                            CGG L K  G++T+P WP+ +YP
Sbjct: 543  PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK-EYP 601

Query: 746  PGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAP 925
            P  +C W ++AP    ISL F  F+ E +  C+YD V V +G ++ D+K  GKFCG + P
Sbjct: 602  PNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSG-LTADSKLHGKFCGSEKP 660

Query: 926  GPISSEGNELLVQFVSDLSVTADGFSASY 1012
              I+S+ N + V+F SD +V+  GF A +
Sbjct: 661  EVITSQYNNMRVEFKSDNTVSKKGFKAHF 689



 Score =  158 bits (399), Expect = 2e-38
 Identities = 84/237 (35%), Positives = 127/237 (53%), Gaps = 3/237 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   VT  SG + S  +P+ YP  KEC W I+      V L+F   D+E  P C YD LE
Sbjct: 736  CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 795

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V+ G       LGRFCG+ +P P++A G+++ LR  SD     +GF      +A+  TE 
Sbjct: 796  VYDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF------QASHSTE- 848

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGG++    K +   +   + +++YP G+ C W I+A     + L F  F++E ++ C
Sbjct: 849  --CGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDC 906

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             YD + +F+G     A RLG++CG   P  + S G+ +LV+F SD ++T  GF   Y
Sbjct: 907  GYDYMELFDG-YDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 962



 Score =  155 bits (392), Expect = 1e-37
 Identities = 89/281 (31%), Positives = 133/281 (47%), Gaps = 36/281 (12%)
 Frame = +2

Query: 284  PNYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELH 463
            P+  R    CGG +T  +G + S G+P  YPPNK CIW +  P    +SL F  F+ E +
Sbjct: 571  PDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGN 630

Query: 464  PSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY- 640
              C+YD +EV +G     +  G+FCG+ +P  + +  N + +   SD     +GF   + 
Sbjct: 631  DVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFF 690

Query: 641  -----------------------------SGRATSGTEHQF----CGGRLEKAQGTLTTP 721
                                         SG      +H      C  ++    GT+T+P
Sbjct: 691  SDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSP 750

Query: 722  NWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKR-- 895
            NWP+  YP    C+W I + P   + LTF + D+E    C YD + V++G    DAK   
Sbjct: 751  NWPDK-YPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGR---DAKAPV 806

Query: 896  LGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRT 1018
            LG+FCG K P P+ + G+ + ++F SD SV   GF AS+ T
Sbjct: 807  LGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHST 847



 Score =  130 bits (326), Expect = 5e-30
 Identities = 73/234 (31%), Positives = 115/234 (49%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G  +S  +PN Y  +  C+W I+V   + + L+F   DL     C YD +E
Sbjct: 311  CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVE 370

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G        GRFCG   P P+V+  +++ +   S     G+GF   Y          
Sbjct: 371  VRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-------- 422

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG ++K  G + +PN+P+ DY P   C W I       + LTF  F++E    C YD
Sbjct: 423  -ICGGDVKKDNGHIQSPNYPD-DYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 480

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + V +G  S+ +  +G++CG + P  I S  + L ++FVSD S+   GF+ ++
Sbjct: 481  YLEVRDGH-SETSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 533



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 41/124 (33%), Positives = 61/124 (49%), Gaps = 4/124 (3%)
 Frame = +2

Query: 311  CGGDVTGESG----YLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG V  E      Y  ++   N YP   +C W I   E   V L F+ F++E    C Y
Sbjct: 849  CGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 908

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATS 658
            D +E+F G  ++  RLGR+CG+  P  + + G+ V ++  SD+    +GF L Y+     
Sbjct: 909  DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 968

Query: 659  GTEH 670
             T H
Sbjct: 969  DTLH 972



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 42/122 (34%), Positives = 56/122 (45%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+ + G  ++P +P   Y   + C W I   P + I L F   DL     C YD V
Sbjct: 311  CGETLQDSTGNFSSPEYPNG-YSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYV 369

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G       R G+FCG K P PI S  + L V+F S  +    GF A Y  +  G  
Sbjct: 370  EVRDGFWRKAPLR-GRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDV 428

Query: 1037 EK 1042
            +K
Sbjct: 429  KK 430


>ref|XP_535142.2| PREDICTED: similar to Neuropilin-1 precursor (Vascular endothelial
            cell growth factor 165 receptor) [Canis familiaris].
          Length = 990

 Score =  151 bits (382), Expect = 1e-36
 Identities = 91/252 (36%), Positives = 134/252 (53%), Gaps = 9/252 (3%)
 Frame = +2

Query: 311  CGGDVTGES-GYLASEGFPNLYPPNKECIWTITVPES-QTVSLSFRV-FDLELHPSCRYD 481
            CG  +  ES GYL S G+P+ Y P+++C W I  P+  Q + ++F   FDLE    C+YD
Sbjct: 94   CGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-DRDCKYD 152

Query: 482  ALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSG 661
             +EV  G   +G+  G+FCG   P+P+V+ G  + ++  SD  T G GF + Y      G
Sbjct: 153  YVEVIDGENENGRPWGKFCGKIAPSPVVSSGPFLFIKFVSDYETHGAGFSIRYE-IFKRG 211

Query: 662  TEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDS-- 835
             E   C        G + +P +PE  YP G+ C++ I AP    I L F  FDLE DS  
Sbjct: 212  PE---CSQNYTAPSGVIKSPGFPEK-YPNGLECTYIIFAPKMSEIILEFESFDLELDSNP 267

Query: 836  ----YCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFS 1003
                +CRYD + +++G   D    +G++CG K PG I S    L + F +D ++  +GFS
Sbjct: 268  PGGMFCRYDRLEIWDG-FPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFS 326

Query: 1004 ASYRTLPRGATE 1039
            A+Y  L    +E
Sbjct: 327  ANYSVLQSSVSE 338



 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 50/172 (29%), Positives = 74/172 (43%), Gaps = 25/172 (14%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPS------C 472
           C  + T  SG + S GFP  YP   EC + I  P+   + L F  FDLEL  +      C
Sbjct: 214 CSQNYTAPSGVIKSPGFPEKYPNGLECTYIIFAPKMSEIILEFESFDLELDSNPPGGMFC 273

Query: 473 RYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRA 652
           RYD LE++ G    G  +GR+CG   P  + +    +++   +D      GF   YS   
Sbjct: 274 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQ 333

Query: 653 TSGTEHQFC-------GGRLEKAQGTLTTP------------NWPESDYPPG 751
           +S +E   C        G +   Q T ++             N+PE+ + PG
Sbjct: 334 SSVSEDFKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPG 385


  Database: RefSeq49_CP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,874,504
  Number of sequences in database:  33,336
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33336
Number of Hits to DB: 69,508,418
Number of extensions: 2367488
Number of successful extensions: 13844
Number of sequences better than 1.0e-05: 62
Number of HSP's gapped: 13413
Number of HSP's successfully gapped: 187
Length of query: 520
Length of database: 18,874,504
Length adjustment: 107
Effective length of query: 413
Effective length of database: 15,307,552
Effective search space: 6322018976
Effective search space used: 6322018976
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-002572
         (1561 letters)

Database: RefSeq49_HP.fasta 
           32,964 sequences; 18,297,164 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_002584.2| procollagen C-endopeptidase enhancer 1 [Homo sa...   714   0.0  
Alignment   gi|NP_037495.1| procollagen C-endopeptidase enhancer 2 precurso...   361   e-100
Alignment   gi|NP_036596.3| tolloid-like protein 1 isoform 1 precursor [Hom...   170   4e-42
Alignment   gi|NP_036597.1| tolloid-like protein 2 precursor [Homo sapiens].     169   7e-42
Alignment   gi|NP_001190.1| bone morphogenetic protein 1 isoform 1 precurso...   166   7e-41
Alignment   gi|NP_006120.1| bone morphogenetic protein 1 isoform 3 precurso...   163   5e-40
Alignment   gi|NP_001019800.1| neuropilin-1 isoform c [Homo sapiens].            153   4e-37
Alignment   gi|NP_001019799.1| neuropilin-1 isoform b [Homo sapiens].            153   4e-37
Alignment   gi|NP_003864.4| neuropilin-1 isoform a [Homo sapiens].               153   4e-37
Alignment   gi|NP_963840.2| CUB domain-containing protein 2 precursor [Homo...   152   6e-37

>ref|NP_002584.2| procollagen C-endopeptidase enhancer 1 [Homo sapiens].
          Length = 449

 Score =  714 bits (1843), Expect = 0.0
 Identities = 353/457 (77%), Positives = 369/457 (80%), Gaps = 4/457 (0%)
 Frame = +2

Query: 203  MLPAATASXXXXXXXXXXXXXFAQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPN 382
            MLPAATAS             FAQGQTPNYTRPVFLCGGDV GESGY+ASEGFPNLYPPN
Sbjct: 1    MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGESGYVASEGFPNLYPPN 60

Query: 383  KECIWTITVPESQTVSLSFRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPL 562
            KECIWTITVPE QTVSLSFRVFDLELHP+CRYDALEVFAGSGTSGQRLGRFCGTFRPAPL
Sbjct: 61   KECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPL 120

Query: 563  VAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDY 742
            VAPGNQVTLRMT+DEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDY
Sbjct: 121  VAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDY 180

Query: 743  PPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKA 922
            PPGISCSWHIIAPPDQVI+LTF KFDLEPD+YCRYDSVSVFNGAVSDD++RLGKFCGD  
Sbjct: 181  PPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAV 240

Query: 923  PGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGATEKAPAQSPGEDARXXXXXXXXX 1102
            PG ISSEGNELLVQFVSDLSVTADGFSASY+TLPRG  ++     P              
Sbjct: 241  PGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTEPKVKLPPKS 300

Query: 1103 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSDGPSVP----CPKQCRRTGTLQSNFCNS 1270
                                            + PS P    CPKQCRRTGTLQSNFC S
Sbjct: 301  QPPEKT-------------------------EESPSAPDAPTCPKQCRRTGTLQSNFCAS 335

Query: 1271 NLVVTATVKSMVRGPGEGLTVTVSLIGVYKTGGLDLPSPPTDTSLKFYAPCKQCPPMKKG 1450
            +LVVTATVKSMVR PGEGL VTVSLIG YKTGGLDLPSPPT  SLKFY PCKQCPPMKKG
Sbjct: 336  SLVVTATVKSMVREPGEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQCPPMKKG 395

Query: 1451 TSYLMMGQVDENRGPILPPESFVVLYRPNQGQILTKL 1561
             SYL+MGQV+ENRGP+LPPESFVVL+RPNQ QILT L
Sbjct: 396  VSYLLMGQVEENRGPVLPPESFVVLHRPNQDQILTNL 432


>ref|NP_037495.1| procollagen C-endopeptidase enhancer 2 precursor [Homo sapiens].
          Length = 415

 Score =  361 bits (927), Expect = e-100
 Identities = 183/427 (42%), Positives = 254/427 (59%), Gaps = 5/427 (1%)
 Frame = +2

Query: 296  RPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCR 475
            RPVF CGG +TGESG++ SEGFP +YPPN +C W ITVPE + V L+FR  DLE    CR
Sbjct: 28   RPVFTCGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCR 87

Query: 476  YDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRAT 655
            YD ++V+ G   +GQR+GRFCGTFRP  LV+ GN++ ++M SD  T G GF+  +S    
Sbjct: 88   YDFVDVYNGHA-NGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEP 146

Query: 656  SGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDS 835
            +    Q+CGG L++  G+  TPNWP+ DYP G++C WHI+AP +Q+I L F KFD+E D+
Sbjct: 147  NERGDQYCGGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDN 206

Query: 836  YCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY- 1012
            YCRYD V+VFNG   +DA+R+GK+CGD  P PI SE NELL+QF+SDLS+TADGF   Y 
Sbjct: 207  YCRYDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHYI 266

Query: 1013 ---RTLPRGATEKAPAQSPGEDARXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1183
               + LP    +      P                                         
Sbjct: 267  FRPKKLPTTTEQPVTTTFP----------------------------------------- 285

Query: 1184 XXXGSDGPSVPCPKQCRRTGTLQSNFCNSNLVVTATVKSMVRGPGEGLTVTVSLIGVYKT 1363
               G       C ++CRRTGTL+ N+C+S+ V+  TV + +   G  L  TVS+I +YK 
Sbjct: 286  VTTGLKPTVALCQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDGS-LHATVSIINIYKE 344

Query: 1364 GGLDLPSPPTDTSLKFYAPCKQCPPMKKGTSYLMMGQVDEN-RGPILPPESFVVLYRPNQ 1540
            G L +     + S +    CKQCP +++G +Y++MGQV E+ RG I+ P SF+++++   
Sbjct: 345  GNLAIQQAGKNMSARLTVVCKQCPLLRRGLNYIIMGQVGEDGRGKIM-PNSFIMMFKTKN 403

Query: 1541 GQILTKL 1561
             ++L  L
Sbjct: 404  QKLLDAL 410


>ref|NP_036596.3| tolloid-like protein 1 isoform 1 precursor [Homo sapiens].
          Length = 1013

 Score =  170 bits (430), Expect = 4e-42
 Identities = 93/269 (34%), Positives = 139/269 (51%), Gaps = 34/269 (12%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGG++    G + S  +P+ Y P KEC+W ITV ES  V L+F+ F++E H +C YD L
Sbjct: 461  ICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYL 520

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGF------------- 628
            EV  G+  +   +GRFCG  +P  + +  N + ++  SD      GF             
Sbjct: 521  EVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAK 580

Query: 629  -------------LLWYSGRATSGTE--------HQFCGGRLEKAQGTLTTPNWPESDYP 745
                         L  Y      G E           CGG L K  GT+TTP WP+ +YP
Sbjct: 581  PDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPK-EYP 639

Query: 746  PGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAP 925
            P  +C W ++AP    IS+ F  F+LE +  C+YD V +++G +S ++K  GKFCG + P
Sbjct: 640  PNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSG-LSSESKLHGKFCGAEVP 698

Query: 926  GPISSEGNELLVQFVSDLSVTADGFSASY 1012
              I+S+ N + ++F SD +V+  GF A +
Sbjct: 699  EVITSQFNNMRIEFKSDNTVSKKGFKAHF 727



 Score =  152 bits (383), Expect = 1e-36
 Identities = 82/240 (34%), Positives = 126/240 (52%), Gaps = 3/240 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   +   SG + S  +P+ YP  KEC W I+      + L+F  F++E H  C YD LE
Sbjct: 774  CEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLE 833

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            VF G       LGR CG   P PLVA GN++ +R  SD     +GF      +AT  TE 
Sbjct: 834  VFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGF------QATHSTE- 886

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGGRL+   K +   +   + +++YP  + C W +++     + L+F  F++E ++ C
Sbjct: 887  --CGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADC 944

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTL 1021
             YD V +F+G +   A  LG+FCG   P  I S G+ +L+ F +D ++   GF   Y+++
Sbjct: 945  GYDYVELFDG-LDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSI 1003



 Score =  144 bits (362), Expect = 3e-34
 Identities = 80/234 (34%), Positives = 117/234 (50%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G L+S GFPN YP    CIW ++V   + + L+F   DL     C YD +E
Sbjct: 349  CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G       LGRFCG   P  L +  +++ +   S     G+GF   Y          
Sbjct: 409  VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEA-------- 460

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG + K +G + +PN+P+ DY P   C W I       + LTF  F++E    C YD
Sbjct: 461  -ICGGEIRKNEGQIQSPNYPD-DYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + V +G  S+++  +G+FCG   P  I S  N L ++FVSD +V   GF+A++
Sbjct: 519  YLEVRDG-TSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF 571



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 41/126 (32%), Positives = 62/126 (49%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+++ G L++P +P   YP    C W +   P + I L F   DL   S C YD +
Sbjct: 349  CGETLQESNGNLSSPGFPNG-YPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYI 407

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G     +  LG+FCGDK P  ++S  + + ++F S  +    GF+A Y  +  G  
Sbjct: 408  EVRDGYWRK-SPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAICGGEI 466

Query: 1037 EKAPAQ 1054
             K   Q
Sbjct: 467  RKNEGQ 472



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 37/124 (29%), Positives = 59/124 (47%), Gaps = 4/124 (3%)
 Frame = +2

Query: 311  CGGDVTGESG----YLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG +  ES     Y  ++   N YP   +C W +       + LSF+ F++E    C Y
Sbjct: 887  CGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGY 946

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATS 658
            D +E+F G  ++   LGRFCG+  P  + + G+ V +   +D+    +GF + Y      
Sbjct: 947  DYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSIRYP 1006

Query: 659  GTEH 670
             T H
Sbjct: 1007 DTTH 1010


>ref|NP_036597.1| tolloid-like protein 2 precursor [Homo sapiens].
          Length = 1015

 Score =  169 bits (428), Expect = 7e-42
 Identities = 94/268 (35%), Positives = 138/268 (51%), Gaps = 34/268 (12%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGGD+  ++G + S  +P+ Y P+KEC+W ITV E   V L+F+ F++E H SC YD LE
Sbjct: 464  CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 523

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY-------SGR 649
            V  G       +G FCG  +P  + +  N++ ++  SD      GF   +       S  
Sbjct: 524  VRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWP 583

Query: 650  ATSGTEHQF---------------------------CGGRLEKAQGTLTTPNWPESDYPP 748
               G EH+                            CGG + K  GT+T+P WP+ +YP 
Sbjct: 584  DHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPK-EYPT 642

Query: 749  GISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG 928
              +C W ++AP    ISL F  F+LE +  C+YD V V +G +S DAK  G+FCG + P 
Sbjct: 643  NKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSG-LSPDAKLHGRFCGSETPE 701

Query: 929  PISSEGNELLVQFVSDLSVTADGFSASY 1012
             I+S+ N + V+F SD +V+  GF A +
Sbjct: 702  VITSQSNNMRVEFKSDNTVSKRGFRAHF 729



 Score =  157 bits (397), Expect = 3e-38
 Identities = 84/270 (31%), Positives = 129/270 (47%), Gaps = 34/270 (12%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG +T  +G + S G+P  YP NK C+W +  P    +SL F VF+LE +  C+YD +E
Sbjct: 620  CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY------SGRA 652
            V +G     +  GRFCG+  P  + +  N + +   SD     RGF   +        + 
Sbjct: 680  VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD 739

Query: 653  TSGTEHQF----------------------------CGGRLEKAQGTLTTPNWPESDYPP 748
              G +H+                             C  ++   +GTL +PNWP+  YP 
Sbjct: 740  NGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDK-YPS 798

Query: 749  GISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG 928
               C+W+I +     + LTF +F++E    C YD + +++G  S  A  LG+FCG K P 
Sbjct: 799  RRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSL-APILGRFCGSKKPD 857

Query: 929  PISSEGNELLVQFVSDLSVTADGFSASYRT 1018
            P  + G+ + ++F SD SV   GF A + T
Sbjct: 858  PTVASGSSMFLRFYSDASVQRKGFQAVHST 887



 Score =  148 bits (373), Expect = 2e-35
 Identities = 81/237 (34%), Positives = 124/237 (52%), Gaps = 3/237 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   ++   G LAS  +P+ YP  +EC W I+      V L+F  F++E H  C YD LE
Sbjct: 776  CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLE 835

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            ++ G  +    LGRFCG+ +P P VA G+ + LR  SD     +GF      +A   TE 
Sbjct: 836  MYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF------QAVHSTE- 888

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGGRL+   + +   +   + +++YP    C W I+A     + LTF  F++E ++ C
Sbjct: 889  --CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADC 946

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             YD +  ++G     A RLG+FCG      I S G+ L+++F +D ++   GF A Y
Sbjct: 947  GYDYMEAYDG-YDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002



 Score =  142 bits (358), Expect = 9e-34
 Identities = 79/234 (33%), Positives = 115/234 (49%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G  ++ GFPN YP    C+W I+V   + + L+F   DL     C YD +E
Sbjct: 351  CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G       LGRFCG   P PLV+  +++ +   S     G+GF   Y          
Sbjct: 411  VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEAT------- 463

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG + K  G + +PN+P+ DY P   C W I       + LTF  F++E    C YD
Sbjct: 464  --CGGDMNKDAGQIQSPNYPD-DYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + V +G   + A  +G FCG + P  + S  N L ++FVSD S+   GF+A++
Sbjct: 521  YLEVRDGPTEESA-LIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF 573



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 45/126 (35%), Positives = 57/126 (45%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+   G  + P +P   YP    C W I   P + I L F   DL     C YD V
Sbjct: 351  CGETLQDTTGNFSAPGFPNG-YPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G     A  LG+FCGDK P P+ S  + L V+F S  ++   GF A+Y     G  
Sbjct: 410  EVRDGYWRK-APLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDM 468

Query: 1037 EKAPAQ 1054
             K   Q
Sbjct: 469  NKDAGQ 474



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 36/115 (31%), Positives = 57/115 (49%), Gaps = 4/115 (3%)
 Frame = +2

Query: 311  CGG----DVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG    +V  +  Y  ++   N YP    C W I   +   V L+FR F++E    C Y
Sbjct: 889  CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYS 643
            D +E + G  +S  RLGRFCG+     + + G+ + +R  +D+    +GF   Y+
Sbjct: 949  DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYT 1003


>ref|NP_001190.1| bone morphogenetic protein 1 isoform 1 precursor [Homo sapiens].
          Length = 730

 Score =  166 bits (419), Expect = 7e-41
 Identities = 98/285 (34%), Positives = 145/285 (50%), Gaps = 34/285 (11%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGGDV  + G++ S  +P+ Y P+K CIW I V E   V L+F+ F++E H SC YD L
Sbjct: 434  ICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYL 493

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY-------SG 646
            EV  G   S   +GR+CG  +P  + +  +++ L+  SD      GF + +       S 
Sbjct: 494  EVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR 553

Query: 647  RATSGTEHQF---------------------------CGGRLEKAQGTLTTPNWPESDYP 745
                G E +                            CGG L K  G++T+P WP+ +YP
Sbjct: 554  PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK-EYP 612

Query: 746  PGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAP 925
            P  +C W ++AP    ISL F  F+ E +  C+YD V V +G ++ D+K  GKFCG + P
Sbjct: 613  PNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSG-LTADSKLHGKFCGSEKP 671

Query: 926  GPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGATEKAPAQSP 1060
              I+S+ N + V+F SD +V+  GF A +       +EK PA  P
Sbjct: 672  EVITSQYNNMRVEFKSDNTVSKKGFKAHF------FSEKRPALQP 710



 Score =  131 bits (329), Expect = 2e-30
 Identities = 73/234 (31%), Positives = 116/234 (49%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G  +S  +PN Y  +  C+W I+V   + + L+F   DL     C YD +E
Sbjct: 322  CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G        GRFCG+  P P+V+  +++ +   S     G+GF   Y          
Sbjct: 382  VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-------- 433

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG ++K  G + +PN+P+ DY P   C W I       + LTF  F++E    C YD
Sbjct: 434  -ICGGDVKKDYGHIQSPNYPD-DYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + V +G  S+ +  +G++CG + P  I S  + L ++FVSD S+   GF+ ++
Sbjct: 492  YLEVRDGH-SESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 40/115 (34%), Positives = 61/115 (53%)
 Frame = +2

Query: 284 PNYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELH 463
           P+  R    CGG +T  +G + S G+P  YPPNK CIW +  P    +SL F  F+ E +
Sbjct: 582 PDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGN 641

Query: 464 PSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGF 628
             C+YD +EV +G     +  G+FCG+ +P  + +  N + +   SD     +GF
Sbjct: 642 DVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF 696



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 42/122 (34%), Positives = 56/122 (45%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+ + G  ++P +P   Y   + C W I   P + I L F   DL     C YD V
Sbjct: 322  CGETLQDSTGNFSSPEYPNG-YSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G       R G+FCG K P PI S  + L V+F S  +    GF A Y  +  G  
Sbjct: 381  EVRDGFWRKAPLR-GRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDV 439

Query: 1037 EK 1042
            +K
Sbjct: 440  KK 441


>ref|NP_006120.1| bone morphogenetic protein 1 isoform 3 precursor [Homo sapiens].
          Length = 986

 Score =  163 bits (412), Expect = 5e-40
 Identities = 93/269 (34%), Positives = 139/269 (51%), Gaps = 34/269 (12%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGGDV  + G++ S  +P+ Y P+K CIW I V E   V L+F+ F++E H SC YD L
Sbjct: 434  ICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYL 493

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY-------SG 646
            EV  G   S   +GR+CG  +P  + +  +++ L+  SD      GF + +       S 
Sbjct: 494  EVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR 553

Query: 647  RATSGTEHQF---------------------------CGGRLEKAQGTLTTPNWPESDYP 745
                G E +                            CGG L K  G++T+P WP+ +YP
Sbjct: 554  PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK-EYP 612

Query: 746  PGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAP 925
            P  +C W ++AP    ISL F  F+ E +  C+YD V V +G ++ D+K  GKFCG + P
Sbjct: 613  PNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSG-LTADSKLHGKFCGSEKP 671

Query: 926  GPISSEGNELLVQFVSDLSVTADGFSASY 1012
              I+S+ N + V+F SD +V+  GF A +
Sbjct: 672  EVITSQYNNMRVEFKSDNTVSKKGFKAHF 700



 Score =  159 bits (402), Expect = 7e-39
 Identities = 85/237 (35%), Positives = 127/237 (53%), Gaps = 3/237 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   VT  SG + S  +P+ YP  KEC W I+      V L+F   D+E  P C YD LE
Sbjct: 747  CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            VF G       LGRFCG+ +P P++A G+++ LR  SD     +GF      +A+  TE 
Sbjct: 807  VFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF------QASHATE- 859

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGG++    K +   +   + +++YP G+ C W I+A     + L F  F++E ++ C
Sbjct: 860  --CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDC 917

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             YD + +F+G     A RLG++CG   P  + S G+ +LV+F SD ++T  GF   Y
Sbjct: 918  GYDYMELFDG-YDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973



 Score =  156 bits (395), Expect = 4e-38
 Identities = 90/281 (32%), Positives = 133/281 (47%), Gaps = 36/281 (12%)
 Frame = +2

Query: 284  PNYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELH 463
            P+  R    CGG +T  +G + S G+P  YPPNK CIW +  P    +SL F  F+ E +
Sbjct: 582  PDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGN 641

Query: 464  PSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY- 640
              C+YD +EV +G     +  G+FCG+ +P  + +  N + +   SD     +GF   + 
Sbjct: 642  DVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFF 701

Query: 641  -----------------------------SGRATSGTEHQF----CGGRLEKAQGTLTTP 721
                                         SG      +H      C  ++    GT+T+P
Sbjct: 702  SDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSP 761

Query: 722  NWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKR-- 895
            NWP+  YP    C+W I + P   + LTF + D+E    C YD + VF+G    DAK   
Sbjct: 762  NWPDK-YPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGR---DAKAPV 817

Query: 896  LGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRT 1018
            LG+FCG K P P+ + G+ + ++F SD SV   GF AS+ T
Sbjct: 818  LGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT 858



 Score =  131 bits (329), Expect = 2e-30
 Identities = 73/234 (31%), Positives = 116/234 (49%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G  +S  +PN Y  +  C+W I+V   + + L+F   DL     C YD +E
Sbjct: 322  CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G        GRFCG+  P P+V+  +++ +   S     G+GF   Y          
Sbjct: 382  VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-------- 433

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG ++K  G + +PN+P+ DY P   C W I       + LTF  F++E    C YD
Sbjct: 434  -ICGGDVKKDYGHIQSPNYPD-DYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + V +G  S+ +  +G++CG + P  I S  + L ++FVSD S+   GF+ ++
Sbjct: 492  YLEVRDGH-SESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 41/124 (33%), Positives = 62/124 (50%), Gaps = 4/124 (3%)
 Frame = +2

Query: 311  CGG----DVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG    DV  +  Y  ++   N YP   +C W I   E   V L F+ F++E    C Y
Sbjct: 860  CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATS 658
            D +E+F G  ++  RLGR+CG+  P  + + G+ V ++  SD+    +GF L Y+     
Sbjct: 920  DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 979

Query: 659  GTEH 670
             T H
Sbjct: 980  DTLH 983



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 42/122 (34%), Positives = 56/122 (45%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+ + G  ++P +P   Y   + C W I   P + I L F   DL     C YD V
Sbjct: 322  CGETLQDSTGNFSSPEYPNG-YSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G       R G+FCG K P PI S  + L V+F S  +    GF A Y  +  G  
Sbjct: 381  EVRDGFWRKAPLR-GRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDV 439

Query: 1037 EK 1042
            +K
Sbjct: 440  KK 441


>ref|NP_001019800.1| neuropilin-1 isoform c [Homo sapiens].
          Length = 609

 Score =  153 bits (387), Expect = 4e-37
 Identities = 91/252 (36%), Positives = 133/252 (52%), Gaps = 9/252 (3%)
 Frame = +2

Query: 311  CGGDVTGES-GYLASEGFPNLYPPNKECIWTITVPES-QTVSLSFRV-FDLELHPSCRYD 481
            CG  +  ES GYL S G+P+ Y P+++C W I  P+  Q + ++F   FDLE    C+YD
Sbjct: 27   CGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-DRDCKYD 85

Query: 482  ALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSG 661
             +EVF G   +G   G+FCG   P P+V+ G  + ++  SD  T G GF + Y      G
Sbjct: 86   YVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYE-IFKRG 144

Query: 662  TEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDS-- 835
             E   C        G + +P +PE  YP  + C++ + AP    I L F  FDLEPDS  
Sbjct: 145  PE---CSQNYTTPSGVIKSPGFPEK-YPNSLECTYIVFAPKMSEIILEFESFDLEPDSNP 200

Query: 836  ----YCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFS 1003
                +CRYD + +++G   D    +G++CG K PG I S    L + F +D ++  +GFS
Sbjct: 201  PGGMFCRYDRLEIWDG-FPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFS 259

Query: 1004 ASYRTLPRGATE 1039
            A+Y  L    +E
Sbjct: 260  ANYSVLQSSVSE 271



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 48/172 (27%), Positives = 74/172 (43%), Gaps = 25/172 (14%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPS------C 472
           C  + T  SG + S GFP  YP + EC + +  P+   + L F  FDLE   +      C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206

Query: 473 RYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRA 652
           RYD LE++ G    G  +GR+CG   P  + +    +++   +D      GF   YS   
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQ 266

Query: 653 TSGTEHQFC-------GGRLEKAQGTLTTP------------NWPESDYPPG 751
           +S +E   C        G +   Q T ++             N+PE+ + PG
Sbjct: 267 SSVSEDFKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPG 318


>ref|NP_001019799.1| neuropilin-1 isoform b [Homo sapiens].
          Length = 644

 Score =  153 bits (387), Expect = 4e-37
 Identities = 91/252 (36%), Positives = 133/252 (52%), Gaps = 9/252 (3%)
 Frame = +2

Query: 311  CGGDVTGES-GYLASEGFPNLYPPNKECIWTITVPES-QTVSLSFRV-FDLELHPSCRYD 481
            CG  +  ES GYL S G+P+ Y P+++C W I  P+  Q + ++F   FDLE    C+YD
Sbjct: 27   CGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-DRDCKYD 85

Query: 482  ALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSG 661
             +EVF G   +G   G+FCG   P P+V+ G  + ++  SD  T G GF + Y      G
Sbjct: 86   YVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYE-IFKRG 144

Query: 662  TEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDS-- 835
             E   C        G + +P +PE  YP  + C++ + AP    I L F  FDLEPDS  
Sbjct: 145  PE---CSQNYTTPSGVIKSPGFPEK-YPNSLECTYIVFAPKMSEIILEFESFDLEPDSNP 200

Query: 836  ----YCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFS 1003
                +CRYD + +++G   D    +G++CG K PG I S    L + F +D ++  +GFS
Sbjct: 201  PGGMFCRYDRLEIWDG-FPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFS 259

Query: 1004 ASYRTLPRGATE 1039
            A+Y  L    +E
Sbjct: 260  ANYSVLQSSVSE 271



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 48/172 (27%), Positives = 74/172 (43%), Gaps = 25/172 (14%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPS------C 472
           C  + T  SG + S GFP  YP + EC + +  P+   + L F  FDLE   +      C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206

Query: 473 RYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRA 652
           RYD LE++ G    G  +GR+CG   P  + +    +++   +D      GF   YS   
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQ 266

Query: 653 TSGTEHQFC-------GGRLEKAQGTLTTP------------NWPESDYPPG 751
           +S +E   C        G +   Q T ++             N+PE+ + PG
Sbjct: 267 SSVSEDFKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPG 318


>ref|NP_003864.4| neuropilin-1 isoform a [Homo sapiens].
          Length = 923

 Score =  153 bits (387), Expect = 4e-37
 Identities = 91/252 (36%), Positives = 133/252 (52%), Gaps = 9/252 (3%)
 Frame = +2

Query: 311  CGGDVTGES-GYLASEGFPNLYPPNKECIWTITVPES-QTVSLSFRV-FDLELHPSCRYD 481
            CG  +  ES GYL S G+P+ Y P+++C W I  P+  Q + ++F   FDLE    C+YD
Sbjct: 27   CGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-DRDCKYD 85

Query: 482  ALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSG 661
             +EVF G   +G   G+FCG   P P+V+ G  + ++  SD  T G GF + Y      G
Sbjct: 86   YVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYE-IFKRG 144

Query: 662  TEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDS-- 835
             E   C        G + +P +PE  YP  + C++ + AP    I L F  FDLEPDS  
Sbjct: 145  PE---CSQNYTTPSGVIKSPGFPEK-YPNSLECTYIVFAPKMSEIILEFESFDLEPDSNP 200

Query: 836  ----YCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFS 1003
                +CRYD + +++G   D    +G++CG K PG I S    L + F +D ++  +GFS
Sbjct: 201  PGGMFCRYDRLEIWDG-FPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFS 259

Query: 1004 ASYRTLPRGATE 1039
            A+Y  L    +E
Sbjct: 260  ANYSVLQSSVSE 271



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 48/172 (27%), Positives = 74/172 (43%), Gaps = 25/172 (14%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPS------C 472
           C  + T  SG + S GFP  YP + EC + +  P+   + L F  FDLE   +      C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206

Query: 473 RYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRA 652
           RYD LE++ G    G  +GR+CG   P  + +    +++   +D      GF   YS   
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQ 266

Query: 653 TSGTEHQFC-------GGRLEKAQGTLTTP------------NWPESDYPPG 751
           +S +E   C        G +   Q T ++             N+PE+ + PG
Sbjct: 267 SSVSEDFKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPG 318


>ref|NP_963840.2| CUB domain-containing protein 2 precursor [Homo sapiens].
          Length = 449

 Score =  152 bits (385), Expect = 6e-37
 Identities = 87/235 (37%), Positives = 119/235 (50%), Gaps = 1/235 (0%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG ++  SG  +S  FP LYP N EC W I V E  +V L+F  FDLE H +C +D LE
Sbjct: 30   CGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFLE 89

Query: 491  VFAG-SGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTE 667
            ++ G S   G  LGRFCG   P P  +  + +++   SD+     GF        ++G +
Sbjct: 90   IYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGF--------SAGYQ 141

Query: 668  HQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRY 847
               CGG L    G LT+P +P ++YP  + C W I A     + L F  F +E +  C Y
Sbjct: 142  KDVCGGVLTGLSGVLTSPEYP-NNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECTY 200

Query: 848  DSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
            D V+V  G       R   +CG   P  + S G+EL V F SD ++   GF A Y
Sbjct: 201  DYVAVLGG---PGPTRGHHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYY 252



 Score =  141 bits (356), Expect = 1e-33
 Identities = 92/253 (36%), Positives = 130/253 (51%), Gaps = 5/253 (1%)
 Frame = +2

Query: 269  AQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVF 448
            + G +  Y + V  CGG +TG SG L S  +PN YP + EC W I       V L F  F
Sbjct: 133  SHGFSAGYQKDV--CGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVDF 190

Query: 449  DLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGF 628
             +E +  C YD + V  G G +  R   +CG+ RP  LV+ G+++ +   SD   GGRGF
Sbjct: 191  QVEGNEECTYDYVAVLGGPGPT--RGHHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGF 248

Query: 629  LLWY-SGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLT 805
              +Y SG          C       +G  ++P +P S YP  I C W I  PP   + + 
Sbjct: 249  KAYYFSGE---------CQEVYMAMRGNFSSPQYP-SSYPNNIRCHWTIRLPPGYQVKVF 298

Query: 806  FGKFDL-EPDSY---CRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVS 973
            F   DL EP+S    C +D ++ F+GA S++A  LG +CG   P P++S  N+LL+   +
Sbjct: 299  FLDLDLEEPNSLTKTCDFDHLAAFDGA-SEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHT 357

Query: 974  DLSVTADGFSASY 1012
            D S T  GFS +Y
Sbjct: 358  DRSTTRRGFSVAY 370



 Score = 89.4 bits (220), Expect = 9e-18
 Identities = 45/113 (39%), Positives = 60/113 (53%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CGG L    G  ++PN+P   YP    CSW I+      + LTF  FDLE    C +D +
Sbjct: 30   CGGVLSAPSGNFSSPNFPRL-YPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFL 88

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYR 1015
             ++NGA  D    LG+FCG   P P +S  + + V F SD  V + GFSA Y+
Sbjct: 89   EIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFSAGYQ 141



 Score = 69.7 bits (169), Expect = 7e-12
 Identities = 42/132 (31%), Positives = 59/132 (44%), Gaps = 4/132 (3%)
 Frame = +2

Query: 338 GYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLE----LHPSCRYDALEVFAGS 505
           G  +S  +P+ YP N  C WTI +P    V + F   DLE    L  +C +D L  F G+
Sbjct: 266 GNFSSPQYPSSYPNNIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGA 325

Query: 506 GTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEHQFCGG 685
                 LG +CG   P P+ +  NQ+ L + +D  T  RGF + Y G          CG 
Sbjct: 326 SEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAYIGGQLG------CGS 379

Query: 686 RLEKAQGTLTTP 721
              + +G    P
Sbjct: 380 GSTEGEGEALQP 391


  Database: RefSeq49_HP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,297,164
  Number of sequences in database:  32,964
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 32964
Number of Hits to DB: 67,523,571
Number of extensions: 2269894
Number of successful extensions: 13089
Number of sequences better than 1.0e-05: 80
Number of HSP's gapped: 12573
Number of HSP's successfully gapped: 315
Length of query: 520
Length of database: 18,297,164
Length adjustment: 107
Effective length of query: 413
Effective length of database: 14,770,016
Effective search space: 6100016608
Effective search space used: 6100016608
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-002572
         (1561 letters)

Database: RefSeq49_MP.fasta 
           30,036 sequences; 15,617,559 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_032814.2| procollagen C-endopeptidase enhancer 1 [Mus mus...   706   0.0  
Alignment   gi|NP_083896.1| procollagen C-endopeptidase enhancer 2 precurso...   375   e-104
Alignment   gi|NP_036034.1| tolloid-like protein 2 precursor [Mus musculus].     174   2e-43
Alignment   gi|NP_033416.2| tolloid-like protein 1 precursor [Mus musculus].     165   8e-41
Alignment   gi|NP_033885.2| bone morphogenetic protein 1 precursor [Mus mus...   164   1e-40
Alignment   gi|NP_766461.1| CUB domain-containing protein 2 precursor [Mus ...   153   4e-37
Alignment   gi|NP_032763.2| neuropilin-1 precursor [Mus musculus].               150   3e-36
Alignment   gi|NP_001074553.1| cubilin precursor [Mus musculus].                 145   9e-35
Alignment   gi|NP_001070875.1| neuropilin-2 isoform 6 precursor [Mus muscul...   143   4e-34
Alignment   gi|NP_001070874.1| neuropilin-2 isoform 5 precursor [Mus muscul...   143   4e-34

>ref|NP_032814.2| procollagen C-endopeptidase enhancer 1 [Mus musculus].
          Length = 468

 Score =  706 bits (1821), Expect = 0.0
 Identities = 349/456 (76%), Positives = 372/456 (81%), Gaps = 3/456 (0%)
 Frame = +2

Query: 203  MLPAATASXXXXXXXXXXXXXFAQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPN 382
            MLPAA  S              A+GQTPNYTRPVFLCGGDVTGESGY+ASEGFPNLYPPN
Sbjct: 1    MLPAALTSFLGPFLLAWVLP-LARGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPN 59

Query: 383  KECIWTITVPESQTVSLSFRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPL 562
            K+CIWTITVPE QTVSLSFRVFD+ELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAP+
Sbjct: 60   KKCIWTITVPEGQTVSLSFRVFDMELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPV 119

Query: 563  VAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDY 742
            VAPGNQVTLRMT+DEGTGGRGFLLWYSGRATSGTEHQFCGGR+EKAQGTLTTPNWPESDY
Sbjct: 120  VAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRMEKAQGTLTTPNWPESDY 179

Query: 743  PPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKA 922
            PPGISCSWHIIAP +QVI LTFGKFD+EPD+YCRYDSVSVFNGAVSDD+KRLGKFCGDKA
Sbjct: 180  PPGISCSWHIIAPSNQVIMLTFGKFDVEPDTYCRYDSVSVFNGAVSDDSKRLGKFCGDKA 239

Query: 923  PGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGATEKAPAQSPGEDAR---XXXXXX 1093
            P PISSEGNELLVQFVSDLSVTADGFSASYRTLPR A EK  A SPGED +         
Sbjct: 240  PSPISSEGNELLVQFVSDLSVTADGFSASYRTLPRDAVEKESALSPGEDVQRGPQSRSDP 299

Query: 1094 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSDGPSVPCPKQCRRTGTLQSNFCNSN 1273
                                                 PS+ CPKQ +R+GTLQSNFC+S+
Sbjct: 300  KTGTGPKVKPPTKPKSQPAETPEASPATQATPVAPAAPSITCPKQYKRSGTLQSNFCSSS 359

Query: 1274 LVVTATVKSMVRGPGEGLTVTVSLIGVYKTGGLDLPSPPTDTSLKFYAPCKQCPPMKKGT 1453
            LVVT TVK+MVRGPGEGLTVTVSL+GVYKTGGLDLPSPP+ TSLK Y PC+Q PPMKKG 
Sbjct: 360  LVVTGTVKTMVRGPGEGLTVTVSLLGVYKTGGLDLPSPPSGTSLKLYVPCRQMPPMKKGA 419

Query: 1454 SYLMMGQVDENRGPILPPESFVVLYRPNQGQILTKL 1561
            SYL+MGQV+ENRGPILPPESFVVLYR NQ QIL  L
Sbjct: 420  SYLLMGQVEENRGPILPPESFVVLYRSNQDQILNNL 455


>ref|NP_083896.1| procollagen C-endopeptidase enhancer 2 precursor [Mus musculus].
          Length = 414

 Score =  375 bits (963), Expect = e-104
 Identities = 197/426 (46%), Positives = 257/426 (60%), Gaps = 5/426 (1%)
 Frame = +2

Query: 269  AQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVF 448
            A+ QTP   RPVF CGG +TGESG++ SEGFP +YPPN +C W ITVPE + V L+FR  
Sbjct: 20   ARPQTPE--RPVFTCGGILTGESGFIGSEGFPGMYPPNSKCTWKITVPEGKVVVLNFRFI 77

Query: 449  DLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGF 628
            DLE    CRYD ++V+ G   +GQR+GRFCGTFRP  LVA GN++T++M SD  T G GF
Sbjct: 78   DLENDNLCRYDFVDVYNGHA-NGQRIGRFCGTFRPGSLVASGNKMTVQMISDANTAGSGF 136

Query: 629  LLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTF 808
            +  YS  A  G   ++CGGRLEK  GT  TPNWP+ DYP G++C WHIIAP +Q+I L F
Sbjct: 137  MATYSAAAPDGKGDRYCGGRLEKPSGTFKTPNWPDRDYPVGVTCVWHIIAPKNQLIELKF 196

Query: 809  GKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVT 988
             KFD+E D+YCRYD V+VFNG   +DAKR+GK+CGD  P PI SE NELL+QF+SDLS+T
Sbjct: 197  EKFDVERDNYCRYDYVAVFNGGEVNDAKRIGKYCGDSPPVPIVSERNELLIQFLSDLSLT 256

Query: 989  ADGFSASY----RTLPRGATEKAPAQSPGEDARXXXXXXXXXXXXXXXXXXXXXXXXXXX 1156
            ADGF   Y    +  P   T       P                                
Sbjct: 257  ADGFIGHYKFRPKKFPTTTTTPVTTTLP-------------------------------- 284

Query: 1157 XXXXXXXXXXXXGSDGPSVPCPKQCRRTGTLQSNFCNSNLVVTATVKSMVRGPGEGLTVT 1336
                        G       C ++CRR GTL+SN+C+SN V+  TV + V   G  L  T
Sbjct: 285  ---------VTTGLKPTVALCQQKCRRMGTLESNYCSSNFVLAGTVITTVTRGGS-LHAT 334

Query: 1337 VSLIGVYKTGGLDLPSPPTDTSLKFYAPCKQCPPMKKGTSYLMMGQVDEN-RGPILPPES 1513
            VS+I +Y+ G L +     + S+K    C+QCP +++G +Y++MGQV E+ RG I+ P S
Sbjct: 335  VSIISIYREGNLAIQQAGKNMSVKLTVVCRQCPLLRRGLNYIIMGQVGEDGRGKIM-PNS 393

Query: 1514 FVVLYR 1531
            FV +++
Sbjct: 394  FVKMFK 399


>ref|NP_036034.1| tolloid-like protein 2 precursor [Mus musculus].
          Length = 1012

 Score =  174 bits (440), Expect = 2e-43
 Identities = 95/269 (35%), Positives = 139/269 (51%), Gaps = 34/269 (12%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGGD+T ++G + S  +P+ Y P+KEC+W ITVP+   V L+F+ F++E H SC YD L
Sbjct: 460  MCGGDITKDAGQIQSPNYPDDYRPSKECVWRITVPDGFHVGLTFQSFEIERHDSCAYDYL 519

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLL----------W 637
            E+  G       +G FCG  +P  + +  N++ ++  SD      GF            W
Sbjct: 520  EIRDGPTEDSTLIGHFCGYEKPEAVKSSANRLWVKFVSDGSINKAGFAANFFKEVDECSW 579

Query: 638  ------------------------YSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYP 745
                                    Y   A   T    CGG + K  GT+T+P WP+ +YP
Sbjct: 580  PDHGGCEQRCVNTLGSYTCACDPGYELAADKKTCEVACGGFITKLNGTITSPGWPK-EYP 638

Query: 746  PGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAP 925
               +C W ++AP    ISL F  F+LE +  C+YD V V +G +S DAK  GKFCG + P
Sbjct: 639  TNKNCVWQVVAPVQYRISLQFEAFELEGNDVCKYDFVEVRSG-LSPDAKLHGKFCGSETP 697

Query: 926  GPISSEGNELLVQFVSDLSVTADGFSASY 1012
              I+S+ N + V+F SD +V+  GF A +
Sbjct: 698  EVITSQSNNMRVEFKSDNTVSKRGFRAHF 726



 Score =  153 bits (387), Expect = 3e-37
 Identities = 82/270 (30%), Positives = 129/270 (47%), Gaps = 34/270 (12%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG +T  +G + S G+P  YP NK C+W +  P    +SL F  F+LE +  C+YD +E
Sbjct: 617  CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPVQYRISLQFEAFELEGNDVCKYDFVE 676

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY------SGRA 652
            V +G     +  G+FCG+  P  + +  N + +   SD     RGF   +        + 
Sbjct: 677  VRSGLSPDAKLHGKFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD 736

Query: 653  TSGTEHQF----------------------------CGGRLEKAQGTLTTPNWPESDYPP 748
              G + +                             C  ++  A+GTL +PNWP+  YP 
Sbjct: 737  NGGCQQECVNTFGSYLCRCRNGYRLHENGHDCKEAGCAYKISSAEGTLMSPNWPDK-YPS 795

Query: 749  GISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG 928
               C+W+I +     + +TF +F++E    C YD + +++G  S  A  LG+FCG K P 
Sbjct: 796  RKECTWNISSTAGHRVKITFSEFEIEQHQECAYDHLELYDGTDSL-APILGRFCGSKKPD 854

Query: 929  PISSEGNELLVQFVSDLSVTADGFSASYRT 1018
            P+ + G+ L ++F SD SV   GF A + T
Sbjct: 855  PVVATGSSLFLRFYSDASVQRKGFQAVHST 884



 Score =  145 bits (366), Expect = 9e-35
 Identities = 79/237 (33%), Positives = 124/237 (52%), Gaps = 3/237 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   ++   G L S  +P+ YP  KEC W I+      V ++F  F++E H  C YD LE
Sbjct: 773  CAYKISSAEGTLMSPNWPDKYPSRKECTWNISSTAGHRVKITFSEFEIEQHQECAYDHLE 832

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            ++ G+ +    LGRFCG+ +P P+VA G+ + LR  SD     +GF      +A   TE 
Sbjct: 833  LYDGTDSLAPILGRFCGSKKPDPVVATGSSLFLRFYSDASVQRKGF------QAVHSTE- 885

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGGRL+   + +   +   + +++YP    C W I+A     + L F  F++E ++ C
Sbjct: 886  --CGGRLKAEVQTKELYSHAQFGDNNYPSQARCDWVIVAEDGYGVELIFRTFEVEEEADC 943

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             YD +  ++G     A RLG+FCG      I S G+ L+++F +D ++   GF A Y
Sbjct: 944  GYDFMEAYDG-YDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFHTDDTINKKGFHARY 999



 Score =  145 bits (365), Expect = 1e-34
 Identities = 78/234 (33%), Positives = 118/234 (50%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G  ++ GFPN YP    C+W I+V   + + L+F   DL     C YD +E
Sbjct: 348  CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIILNFTSMDLFKSRLCWYDYVE 407

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            +  G       LGRFCG   P  LV+  +++ +   S   + G+GF   Y          
Sbjct: 408  IRDGYWRKAPLLGRFCGDKIPESLVSSDSRLWVEFRSSSSSLGKGFFAVYEA-------- 459

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG + K  G + +PN+P+ DY P   C W I  P    + LTF  F++E    C YD
Sbjct: 460  -MCGGDITKDAGQIQSPNYPD-DYRPSKECVWRITVPDGFHVGLTFQSFEIERHDSCAYD 517

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + + +G  ++D+  +G FCG + P  + S  N L V+FVSD S+   GF+A++
Sbjct: 518  YLEIRDGP-TEDSTLIGHFCGYEKPEAVKSSANRLWVKFVSDGSINKAGFAANF 570



 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 44/126 (34%), Positives = 55/126 (43%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+   G  + P +P   YP    C W I   P + I L F   DL     C YD V
Sbjct: 348  CGETLQDTTGNFSAPGFPNG-YPSYSHCVWRISVTPGEKIILNFTSMDLFKSRLCWYDYV 406

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             + +G     A  LG+FCGDK P  + S  + L V+F S  S    GF A Y  +  G  
Sbjct: 407  EIRDGYWRK-APLLGRFCGDKIPESLVSSDSRLWVEFRSSSSSLGKGFFAVYEAMCGGDI 465

Query: 1037 EKAPAQ 1054
             K   Q
Sbjct: 466  TKDAGQ 471



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
 Frame = +2

Query: 311  CGG----DVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG    +V  +  Y  ++   N YP    C W I   +   V L FR F++E    C Y
Sbjct: 886  CGGRLKAEVQTKELYSHAQFGDNNYPSQARCDWVIVAEDGYGVELIFRTFEVEEEADCGY 945

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYS 643
            D +E + G  +S  RLGRFCG+     + + G+ + +R  +D+    +GF   Y+
Sbjct: 946  DFMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFHTDDTINKKGFHARYT 1000


>ref|NP_033416.2| tolloid-like protein 1 precursor [Mus musculus].
          Length = 1013

 Score =  165 bits (418), Expect = 8e-41
 Identities = 92/269 (34%), Positives = 135/269 (50%), Gaps = 34/269 (12%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGG++    G + S  +P+ Y P KEC+W I V E   V L+F+ F++E H SC YD L
Sbjct: 461  ICGGEIRKNEGQIQSPNYPDDYRPMKECVWKIMVSEGYHVGLTFQAFEIERHDSCAYDHL 520

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGF------------- 628
            EV  G+  +   +GRFCG  +P  + +  N + ++  SD      GF             
Sbjct: 521  EVRDGASENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAK 580

Query: 629  -------------LLWYSGRATSGTE--------HQFCGGRLEKAQGTLTTPNWPESDYP 745
                         L  Y      G E           CGG L K  GT+TTP WP+ +YP
Sbjct: 581  PDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPK-EYP 639

Query: 746  PGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAP 925
            P  +C W +IAP    IS+ F  F+LE +  C+YD V +++G +S ++K  GKFCG   P
Sbjct: 640  PNKNCVWQVIAPSQYRISVKFEFFELEGNEVCKYDYVEIWSG-LSSESKLHGKFCGADIP 698

Query: 926  GPISSEGNELLVQFVSDLSVTADGFSASY 1012
              ++S  N + ++F SD +V+  GF A +
Sbjct: 699  EVMTSHFNNMRIEFKSDNTVSKKGFKAHF 727



 Score =  151 bits (382), Expect = 1e-36
 Identities = 82/240 (34%), Positives = 128/240 (53%), Gaps = 3/240 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   +   SG + S  +P+ YP  KEC W I+      ++L+F  F++E H  C YD LE
Sbjct: 774  CEQKIHSPSGLITSPNWPDKYPSRKECTWVISAIPGHRITLAFNEFEVEQHQECAYDHLE 833

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            +F G       LGR CG+  P PL+A GN++ +R  SD     +GF      +AT  TE 
Sbjct: 834  IFDGETEKSPILGRLCGSKIPDPLMATGNEMFIRFISDASVQRKGF------QATHSTE- 886

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGGRL+   K +   +   + +++YP  + C W +++     + L+F  F++E ++ C
Sbjct: 887  --CGGRLKAESKPRDLYSHAQFGDNNYPGQLDCEWLLVSERGSRLELSFQTFEVEEEADC 944

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTL 1021
             YD V VF+G +S  A  LG+FCG   P  I S G+  L+ F +D ++   GF   Y+++
Sbjct: 945  GYDYVEVFDG-LSSKAVGLGRFCGSGPPEEIYSIGDVALIHFHTDDTINKKGFYIRYKSI 1003



 Score =  144 bits (362), Expect = 2e-34
 Identities = 81/234 (34%), Positives = 118/234 (50%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   SG L+S GFPN YP    CIW ++V   + + L+F   DL     C YD +E
Sbjct: 349  CGETLQESSGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G       LGRFCG      L +  +++ +   S     G+GF   Y          
Sbjct: 409  VRDGYWRKSPLLGRFCGDKVAGVLTSTDSRMWIEFRSSSNWVGKGFAAVYEA-------- 460

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG + K +G + +PN+P+ DY P   C W I+      + LTF  F++E    C YD
Sbjct: 461  -ICGGEIRKNEGQIQSPNYPD-DYRPMKECVWKIMVSEGYHVGLTFQAFEIERHDSCAYD 518

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + V +GA S+++  +G+FCG   P  I S  N L ++FVSD +V   GF+A++
Sbjct: 519  HLEVRDGA-SENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF 571



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 41/126 (32%), Positives = 62/126 (49%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+++ G L++P +P   YP    C W +   P + I L F   DL   S C YD +
Sbjct: 349  CGETLQESSGNLSSPGFPNG-YPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYI 407

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G     +  LG+FCGDK  G ++S  + + ++F S  +    GF+A Y  +  G  
Sbjct: 408  EVRDGYWRK-SPLLGRFCGDKVAGVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAICGGEI 466

Query: 1037 EKAPAQ 1054
             K   Q
Sbjct: 467  RKNEGQ 472



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 37/124 (29%), Positives = 57/124 (45%), Gaps = 4/124 (3%)
 Frame = +2

Query: 311  CGGDVTGESG----YLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG +  ES     Y  ++   N YP   +C W +       + LSF+ F++E    C Y
Sbjct: 887  CGGRLKAESKPRDLYSHAQFGDNNYPGQLDCEWLLVSERGSRLELSFQTFEVEEEADCGY 946

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATS 658
            D +EVF G  +    LGRFCG+  P  + + G+   +   +D+    +GF + Y      
Sbjct: 947  DYVEVFDGLSSKAVGLGRFCGSGPPEEIYSIGDVALIHFHTDDTINKKGFYIRYKSIRYP 1006

Query: 659  GTEH 670
             T H
Sbjct: 1007 ETMH 1010


>ref|NP_033885.2| bone morphogenetic protein 1 precursor [Mus musculus].
          Length = 991

 Score =  164 bits (416), Expect = 1e-40
 Identities = 93/269 (34%), Positives = 140/269 (52%), Gaps = 34/269 (12%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGGDV  ++G++ S  +P+ Y P+K CIW I V E   V L+F+ F++E H SC YD L
Sbjct: 439  ICGGDVKKDNGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYL 498

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY-------SG 646
            EV  G   S   +GR+CG  +P  + +  +++ L+  SD      GF + +       S 
Sbjct: 499  EVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR 558

Query: 647  RATSGTEHQF---------------------------CGGRLEKAQGTLTTPNWPESDYP 745
                G E +                            CGG L K  G++T+P WP+ +YP
Sbjct: 559  PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK-EYP 617

Query: 746  PGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAP 925
            P  +C W ++AP    ISL F  F+ E +  C+YD V V +G ++ D+K  GKFCG + P
Sbjct: 618  PNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSG-LTADSKLHGKFCGSEKP 676

Query: 926  GPISSEGNELLVQFVSDLSVTADGFSASY 1012
              I+S+ N + V+F SD +V+  GF A +
Sbjct: 677  EVITSQYNNMRVEFKSDNTVSKKGFKAHF 705



 Score =  159 bits (402), Expect = 6e-39
 Identities = 85/237 (35%), Positives = 127/237 (53%), Gaps = 3/237 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   VT  SG + S  +P+ YP  KEC W I+      V L+F   D+E  P C YD LE
Sbjct: 752  CEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLE 811

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            VF G       LGRFCG+ +P P++A GN++ LR  SD     +GF      +A+  TE 
Sbjct: 812  VFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGF------QASHSTE- 864

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGG++    K +   +   + +++YP G+ C W I+A     + L F  F++E ++ C
Sbjct: 865  --CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDC 922

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             YD + +F+G     A RLG++CG   P  + S G+ +LV+F SD +++  GF   Y
Sbjct: 923  GYDYIELFDG-YDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRY 978



 Score =  158 bits (399), Expect = 1e-38
 Identities = 91/281 (32%), Positives = 133/281 (47%), Gaps = 36/281 (12%)
 Frame = +2

Query: 284  PNYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELH 463
            P+  R    CGG +T  +G + S G+P  YPPNK CIW +  P    +SL F  F+ E +
Sbjct: 587  PDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGN 646

Query: 464  PSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY- 640
              C+YD +EV +G     +  G+FCG+ +P  + +  N + +   SD     +GF   + 
Sbjct: 647  DVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFF 706

Query: 641  -----------------------------SGRATSGTEHQF----CGGRLEKAQGTLTTP 721
                                         SG      +H      C  ++    GT+T+P
Sbjct: 707  SDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSP 766

Query: 722  NWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKR-- 895
            NWP+  YP    C+W I + P   + LTF + D+E    C YD + VF+G    DAK   
Sbjct: 767  NWPDK-YPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGR---DAKAPV 822

Query: 896  LGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRT 1018
            LG+FCG K P P+ + GN + ++F SD SV   GF AS+ T
Sbjct: 823  LGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHST 863



 Score =  130 bits (328), Expect = 2e-30
 Identities = 73/234 (31%), Positives = 115/234 (49%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G  +S  +PN Y  +  C+W I+V   + + L+F   DL     C YD +E
Sbjct: 327  CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVE 386

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G        GRFCG   P P+V+  +++ +   S     G+GF   Y          
Sbjct: 387  VRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-------- 438

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG ++K  G + +PN+P+ DY P   C W I       + LTF  F++E    C YD
Sbjct: 439  -ICGGDVKKDNGHIQSPNYPD-DYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 496

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + V +G  S+ +  +G++CG + P  I S  + L ++FVSD S+   GF+ ++
Sbjct: 497  YLEVRDGH-SESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 549



 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 41/124 (33%), Positives = 62/124 (50%), Gaps = 4/124 (3%)
 Frame = +2

Query: 311  CGG----DVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG    DV  +  Y  ++   N YP   +C W I   E   V L F+ F++E    C Y
Sbjct: 865  CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 924

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATS 658
            D +E+F G  ++  RLGR+CG+  P  + + G+ V ++  SD+    +GF L Y+     
Sbjct: 925  DYIELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTSTKFQ 984

Query: 659  GTEH 670
             T H
Sbjct: 985  DTLH 988



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 42/122 (34%), Positives = 56/122 (45%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+ + G  ++P +P   Y   + C W I   P + I L F   DL     C YD V
Sbjct: 327  CGETLQDSTGNFSSPEYPNG-YSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYV 385

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G       R G+FCG K P PI S  + L V+F S  +    GF A Y  +  G  
Sbjct: 386  EVRDGFWRKAPLR-GRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDV 444

Query: 1037 EK 1042
            +K
Sbjct: 445  KK 446


>ref|NP_766461.1| CUB domain-containing protein 2 precursor [Mus musculus].
          Length = 427

 Score =  153 bits (386), Expect = 4e-37
 Identities = 86/235 (36%), Positives = 118/235 (50%), Gaps = 1/235 (0%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG ++  SG  +S  FP+LYP N EC W I V E  +V L+F  FDLE H +C +D LE
Sbjct: 30   CGGVLSAPSGNFSSPNFPSLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCGFDFLE 89

Query: 491  VFAG-SGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTE 667
            ++ G SG  G  LGRFCG   P P  +  + +++   SD+    RGF        ++G +
Sbjct: 90   IYNGASGDKGNLLGRFCGQVPPPPFTSSWHVMSVVFHSDKHVASRGF--------SAGYQ 141

Query: 668  HQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRY 847
               CGG L    G L++P +P ++YP  + C W I A     + L F  F +E    C Y
Sbjct: 142  KDVCGGVLTGLSGVLSSPEYP-NNYPNNVECHWLIRASGPAAVKLVFVDFQVEGSDECMY 200

Query: 848  DSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
            D V+V              +CG   P    S G+EL V F SD ++   GF A Y
Sbjct: 201  DYVAVLGAPGPAHGHH---YCGRTRPPTFVSLGHELQVVFKSDFNIGGRGFKAHY 252



 Score =  130 bits (327), Expect = 3e-30
 Identities = 85/253 (33%), Positives = 127/253 (50%), Gaps = 5/253 (1%)
 Frame = +2

Query: 269  AQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVF 448
            ++G +  Y + V  CGG +TG SG L+S  +PN YP N EC W I       V L F  F
Sbjct: 133  SRGFSAGYQKDV--CGGVLTGLSGVLSSPEYPNNYPNNVECHWLIRASGPAAVKLVFVDF 190

Query: 449  DLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGF 628
             +E    C YD + V    G +      +CG  RP   V+ G+++ +   SD   GGRGF
Sbjct: 191  QVEGSDECMYDYVAVLGAPGPAHGH--HYCGRTRPPTFVSLGHELQVVFKSDFNIGGRGF 248

Query: 629  LL-WYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLT 805
               ++SG          C       +G  ++P +P + YP  I C W I  PP   + + 
Sbjct: 249  KAHYFSGE---------CQEVFTAVRGNFSSPQYPGA-YPNNIRCHWTIRLPPGYRVKVF 298

Query: 806  FGKFDL-EPDSY---CRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVS 973
                 L EP+S    C +D ++ F+GA S++A+ LGK+CG   P P++S  N++L+   +
Sbjct: 299  ILDLGLEEPNSLTRTCDFDHLAAFDGA-SEEAQLLGKWCGHHLPPPVTSSRNQVLLLLHT 357

Query: 974  DLSVTADGFSASY 1012
            D S +  GFS +Y
Sbjct: 358  DRSTSGRGFSVAY 370



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 49/125 (39%), Positives = 64/125 (51%)
 Frame = +2

Query: 641  SGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFD 820
            S   T   E   CGG L    G  ++PN+P S YP    CSW I+      + LTF  FD
Sbjct: 18   SDPGTQAMEGVKCGGVLSAPSGNFSSPNFP-SLYPYNTECSWLIVVAEGSSVLLTFHAFD 76

Query: 821  LEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGF 1000
            LE    C +D + ++NGA  D    LG+FCG   P P +S  + + V F SD  V + GF
Sbjct: 77   LEYHDTCGFDFLEIYNGASGDKGNLLGRFCGQVPPPPFTSSWHVMSVVFHSDKHVASRGF 136

Query: 1001 SASYR 1015
            SA Y+
Sbjct: 137  SAGYQ 141



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 43/128 (33%), Positives = 58/128 (45%), Gaps = 4/128 (3%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLE----LHPSCRY 478
           C    T   G  +S  +P  YP N  C WTI +P    V +      LE    L  +C +
Sbjct: 257 CQEVFTAVRGNFSSPQYPGAYPNNIRCHWTIRLPPGYRVKVFILDLGLEEPNSLTRTCDF 316

Query: 479 DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATS 658
           D L  F G+    Q LG++CG   P P+ +  NQV L + +D  T GRGF + Y G    
Sbjct: 317 DHLAAFDGASEEAQLLGKWCGHHLPPPVTSSRNQVLLLLHTDRSTSGRGFSVAYIGGQLG 376

Query: 659 GTEHQFCG 682
               + CG
Sbjct: 377 VCPWELCG 384


>ref|NP_032763.2| neuropilin-1 precursor [Mus musculus].
          Length = 923

 Score =  150 bits (379), Expect = 3e-36
 Identities = 90/252 (35%), Positives = 133/252 (52%), Gaps = 9/252 (3%)
 Frame = +2

Query: 311  CGGDVTGES-GYLASEGFPNLYPPNKECIWTITVPES-QTVSLSFRV-FDLELHPSCRYD 481
            CGG +  E+ GYL S G+P+ Y P+++C W I  PE  Q + ++F   FDLE    C+YD
Sbjct: 27   CGGTIKIENPGYLTSPGYPHSYHPSEKCEWLIQAPEPYQRIMINFNPHFDLE-DRDCKYD 85

Query: 482  ALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSG 661
             +EV  G    G+  G+FCG   P+P+V+ G  + ++  SD  T G GF + Y      G
Sbjct: 86   YVEVIDGENEGGRLWGKFCGKIAPSPVVSSGPFLFIKFVSDYETHGAGFSIRYE-IFKRG 144

Query: 662  TEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDS-- 835
             E   C        G + +P +PE  YP  + C++ I AP    I L F  FDLE DS  
Sbjct: 145  PE---CSQNYTAPTGVIKSPGFPEK-YPNSLECTYIIFAPKMSEIILEFESFDLEQDSNP 200

Query: 836  ----YCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFS 1003
                +CRYD + +++G   +    +G++CG K PG I S    L + F +D ++  +GFS
Sbjct: 201  PGGMFCRYDRLEIWDG-FPEVGPHIGRYCGQKTPGRIRSSSGVLSMVFYTDSAIAKEGFS 259

Query: 1004 ASYRTLPRGATE 1039
            A+Y  L    +E
Sbjct: 260  ANYSVLQSSISE 271



 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 48/172 (27%), Positives = 74/172 (43%), Gaps = 25/172 (14%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPS------C 472
           C  + T  +G + S GFP  YP + EC + I  P+   + L F  FDLE   +      C
Sbjct: 147 CSQNYTAPTGVIKSPGFPEKYPNSLECTYIIFAPKMSEIILEFESFDLEQDSNPPGGMFC 206

Query: 473 RYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRA 652
           RYD LE++ G    G  +GR+CG   P  + +    +++   +D      GF   YS   
Sbjct: 207 RYDRLEIWDGFPEVGPHIGRYCGQKTPGRIRSSSGVLSMVFYTDSAIAKEGFSANYSVLQ 266

Query: 653 TSGTEHQFC-------GGRLEKAQGTLTTP------------NWPESDYPPG 751
           +S +E   C        G +   Q T ++             N+PE+ + PG
Sbjct: 267 SSISEDFKCMEALGMESGEIHSDQITASSQYGTNWSVERSRLNYPENGWTPG 318


>ref|NP_001074553.1| cubilin precursor [Mus musculus].
          Length = 3623

 Score =  145 bits (366), Expect = 9e-35
 Identities = 92/253 (36%), Positives = 136/253 (53%), Gaps = 8/253 (3%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNL-YPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            CGG  +G  G L S  F    YP N  C++++ V   + + L F  F++     C +D L
Sbjct: 3037 CGGIYSGTYGVLNSPSFSYTNYPNNVYCVYSLQVRNDRLILLRFNDFEIVPSNLCSHDYL 3096

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTE 667
            EVF G     + +G+FCG+  P  + +  N +TL   +D     RG+ +  S R T G +
Sbjct: 3097 EVFDGPSIGNRSIGKFCGSTLPQVIKSTNNSLTLLFKTDSSQTARGWKV--SFRETIGPQ 3154

Query: 668  HQFCGGRLEKAQGTLTTPNWPESD--YPPGISCSWHIIAPPDQVISLTFGKFDLEPDS-- 835
             Q CGG L +   +  +P+  +SD  Y  G++C W+IIAP ++++ LTF  F LE  S  
Sbjct: 3155 -QGCGGYLTEDSKSFVSPD-HDSDGLYDKGLNCIWYIIAPENKLVKLTFNAFTLEEPSSP 3212

Query: 836  -YCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
              C +D V + +GA S ++   G+FCG   P P  S GN L VQFVSD+S+   GF+A+Y
Sbjct: 3213 GKCTFDYVQIADGA-SINSYLGGRFCGSSRPAPFISSGNFLTVQFVSDISIQMRGFNATY 3271

Query: 1013 R--TLPRGATEKA 1045
                +P G T  A
Sbjct: 3272 TFVDMPCGGTYNA 3284



 Score =  144 bits (363), Expect = 2e-34
 Identities = 97/301 (32%), Positives = 143/301 (47%), Gaps = 11/301 (3%)
 Frame = +2

Query: 146  CSTQLLPLS*GPQRLS-------PPTMLPAATASXXXXXXXXXXXXXFAQGQTPNYTRPV 304
            CST  L L  GPQR+        PP    A T S               +G   ++   +
Sbjct: 1333 CSTDYLELYDGPQRIGRYCGENIPPP--GATTGSKLIVVFHTDGVDSGEKGFKMHWF--I 1388

Query: 305  FLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDA 484
              CGG+++G  G  +S G+PN YP NKECIW I V    ++ L+   FD+E H SC+YD 
Sbjct: 1389 HGCGGEMSGTMGSFSSPGYPNSYPHNKECIWNIRVAPGNSIQLTIHDFDVEYHASCKYDT 1448

Query: 485  LEVFAGSGTSGQRLGRFCG---TFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRAT 655
            LE++ G      R+ + C    +  P  + +  N++ +R  +D    GRGF    S RA 
Sbjct: 1449 LEIYTGLDFHSPRIAQLCSRSPSANPMQISSTDNELAIRFKTDSSLNGRGFNA--SWRAV 1506

Query: 656  SGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDS 835
             G     CGG  + ++G + +PN+P ++Y     CSW I       + L    FDLE   
Sbjct: 1507 PGG----CGGIFQVSRGEIHSPNYP-NNYRANTECSWIIQVEKYHRVLLNITDFDLEATD 1561

Query: 836  YCRYDSVSVFNGAVSDDAKRLGKFCG-DKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             C    +  ++G+ S +  R+   CG  + P  I+S GN L V+F S  S  + GF A +
Sbjct: 1562 SC----LMTYDGSSSANT-RVATVCGRQQPPNSITSSGNSLFVRFQSGSSSQSRGFRAQF 1616

Query: 1013 R 1015
            R
Sbjct: 1617 R 1617



 Score =  143 bits (360), Expect = 4e-34
 Identities = 80/236 (33%), Positives = 119/236 (50%), Gaps = 2/236 (0%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG  TGE+G ++S  +PNLY    +C W +  PE  T++L+F  F +E HP+C  D++ 
Sbjct: 2689 CGGIQTGENGVISSPNYPNLYSRWTQCSWLLEAPEGHTITLTFSDFSVENHPTCTSDSVT 2748

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G       +GR+CG   P P+ +  NQ+ +   ++     RGF       AT  T  
Sbjct: 2749 VRNGDSPGSPIIGRYCGQSVPGPIQSGSNQLVVTFNTNNQGQSRGFY------ATWNTNT 2802

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEP--DSYCR 844
              CGG L    GT+ +P+WP++ +P    CSW  +    +   ++F      P  DS CR
Sbjct: 2803 LGCGGTLHSDNGTIKSPHWPQT-FPENSRCSWTAVTHESKHWEISFDSNFRIPSSDSQCR 2861

Query: 845  YDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
               V V+ G +  +   L   CG+ AP PI + GN     F S+  + A GFSAS+
Sbjct: 2862 NSFVKVWEGMLETNDALLATSCGNVAPSPIVTLGNIFTAVFQSE-EMPAQGFSASF 2916



 Score =  135 bits (339), Expect = 1e-31
 Identities = 82/240 (34%), Positives = 118/240 (49%), Gaps = 3/240 (1%)
 Frame = +2

Query: 311  CGGDV-TGESGYLASEGFPNLYPPNKECIWTITV-PESQTVSLSFRVFDLELHPSCRYDA 484
            CG  + T  S  ++S  +P  YP N+ C W I   P    ++LSF  F L+    C  D 
Sbjct: 1620 CGAHIITDSSDSISSPLYPANYPNNQNCTWIIEAQPPFNHIALSFTHFHLQSSTDCTRDF 1679

Query: 485  LEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGT 664
            +E+  G  +     GR+CGT  P P+++ GN +T+R  SD   G  GF   YS   ++  
Sbjct: 1680 VEILDGRDSDAPVQGRYCGTSLPHPIISFGNALTVRFVSDSVYGFDGFHAIYSASTSA-- 1737

Query: 665  EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCR 844
                CGG      G   +P +PE DY     C W+I + P   + L+F  F LE    C 
Sbjct: 1738 ----CGGTFYTGDGIFNSPGYPE-DYHSNTECVWNIASSPGNHLQLSFLSFQLENSLNCN 1792

Query: 845  YDSVSVFNGAVSDDAKRLGKFCGDKAPGPISS-EGNELLVQFVSDLSVTADGFSASYRTL 1021
             D V +  G  +     +G++CG+  PG  SS EG+ L V+FVSD S T  GF A ++ +
Sbjct: 1793 KDFVEIREGNAT--GHLMGRYCGNSLPGNYSSIEGHNLWVRFVSDGSGTGMGFQARFKNI 1850



 Score =  131 bits (329), Expect = 2e-30
 Identities = 79/241 (32%), Positives = 124/241 (51%), Gaps = 5/241 (2%)
 Frame = +2

Query: 323  VTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALEVFAG 502
            V   SG L S  +PN Y  ++ C WTI      TV+ +F  FD+E + +C  D LE++ G
Sbjct: 1284 VNKTSGILESINYPNPYDKDQRCNWTIQATTGNTVNYTFLEFDVENYVNCSTDYLELYDG 1343

Query: 503  SGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDE-GTGGRGFLL-WYSGRATSGTEHQF 676
                 QR+GR+CG   P P    G+++ +   +D   +G +GF + W+            
Sbjct: 1344 P----QRIGRYCGENIPPPGATTGSKLIVVFHTDGVDSGEKGFKMHWFI---------HG 1390

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CGG +    G+ ++P +P S YP    C W+I   P   I LT   FD+E  + C+YD++
Sbjct: 1391 CGGEMSGTMGSFSSPGYPNS-YPHNKECIWNIRVAPGNSIQLTIHDFDVEYHASCKYDTL 1449

Query: 857  SVFNGAVSDDAKRLGKFCGDKA---PGPISSEGNELLVQFVSDLSVTADGFSASYRTLPR 1027
             ++ G +   + R+ + C       P  ISS  NEL ++F +D S+   GF+AS+R +P 
Sbjct: 1450 EIYTG-LDFHSPRIAQLCSRSPSANPMQISSTDNELAIRFKTDSSLNGRGFNASWRAVPG 1508

Query: 1028 G 1030
            G
Sbjct: 1509 G 1509



 Score =  130 bits (328), Expect = 2e-30
 Identities = 72/242 (29%), Positives = 116/242 (47%)
 Frame = +2

Query: 299  PVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            P   CGG ++G  G  A +   + Y  N  C W +   E + + ++F  FDLE   +C  
Sbjct: 470  PQAACGGILSGTQGTFAYQSPNDTYVHNVNCFWVVRTDEEKVLHITFTFFDLESASNCPR 529

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATS 658
            + L++  G  ++   LGR+CG+  P  + +  N +   + S+    GRGF   +  +   
Sbjct: 530  EYLQIHDGDSSADFPLGRYCGSTPPQGVHSSANSLYFHLYSEYIKRGRGFTARWEAKLPE 589

Query: 659  GTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSY 838
                  CGG L    G++T+P +P  +YPPG  C W+++  P  +I+ TFG   LE  + 
Sbjct: 590  ------CGGILTGNYGSITSPGYP-GNYPPGRDCVWNLLVSPGSLITFTFGTLSLESHND 642

Query: 839  CRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRT 1018
            C  D + + +G    D   LGKFC   +  P+ + G    + F SD   +  GF  +Y T
Sbjct: 643  CSKDYLEIRDGPFHHD-PILGKFCTSLSTPPLQTTGPAARIHFHSDSETSDKGFHITYLT 701

Query: 1019 LP 1024
             P
Sbjct: 702  TP 703



 Score =  126 bits (317), Expect = 4e-29
 Identities = 79/238 (33%), Positives = 116/238 (48%), Gaps = 2/238 (0%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLE--LHPSCRYD 481
            +C  D T   G L+S  FPN YP N  C++ ITV  +Q ++L F  F LE    P C  D
Sbjct: 1047 VCLYDYTDNFGRLSSPNFPNNYPHNWNCVYRITVGLNQQIALHFTDFALEDYFGPKC-VD 1105

Query: 482  ALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSG 661
             +E+  G   +   +G +CG+  P  +++  N++ LR  SD     RGF  ++   +T  
Sbjct: 1106 FVEIRDGGFETSPLIGIYCGSVFPPRIISHSNKLWLRFKSDTALTARGFSAYWDASSTG- 1164

Query: 662  TEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
                 CGG L    G LT+PN+P   Y     C W + A       L F  F LE    C
Sbjct: 1165 -----CGGNLTTPTGVLTSPNYP-MPYYHSSECYWRLEASRGSPFLLEFQDFHLEHHPNC 1218

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYR 1015
              D ++VF+G  S +++ + K CGD  P PI S  + +L++  +D      GF  +YR
Sbjct: 1219 SLDYLAVFDGP-STNSRLINKLCGDTPPAPIRSSKDIVLLKLRTDAGQQGRGFEINYR 1275



 Score =  126 bits (317), Expect = 4e-29
 Identities = 87/255 (34%), Positives = 126/255 (49%), Gaps = 7/255 (2%)
 Frame = +2

Query: 275  GQTPNYTRPV-FLCGGDVTGESG-YLASEGFPNL--YPPNKECIWTITVP--ESQTVSLS 436
            G T +YT     +CGG +   SG   +S G+  +  Y  N +C WT++ P  E+ ++S+ 
Sbjct: 2557 GFTASYTSSEDAVCGGTLPSVSGGNFSSPGYNGIRDYARNLDCEWTLSNPNRENSSISIH 2616

Query: 437  FRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRP-APLVAPGNQVTLRMTSDEGT 613
            F    LE H  C +D LE   G+   G  + +FC    P  PLV P  QV +   S+E  
Sbjct: 2617 FLGLSLESHQDCTFDVLEFRVGNA-DGPLIEKFCSLSAPRVPLVIPYPQVWIHFVSNERV 2675

Query: 614  GGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQV 793
               GF + YS           CGG      G +++PN+P   Y     CSW + AP    
Sbjct: 2676 EYTGFYVEYS--------FTNCGGIQTGENGVISSPNYPNL-YSRWTQCSWLLEAPEGHT 2726

Query: 794  ISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVS 973
            I+LTF  F +E    C  DSV+V NG  S  +  +G++CG   PGPI S  N+L+V F +
Sbjct: 2727 ITLTFSDFSVENHPTCTSDSVTVRNGD-SPGSPIIGRYCGQSVPGPIQSGSNQLVVTFNT 2785

Query: 974  DLSVTADGFSASYRT 1018
            +    + GF A++ T
Sbjct: 2786 NNQGQSRGFYATWNT 2800



 Score =  125 bits (314), Expect = 9e-29
 Identities = 77/239 (32%), Positives = 119/239 (49%), Gaps = 7/239 (2%)
 Frame = +2

Query: 320  DVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALEVFA 499
            ++ G  G +A+  +P  YP N    WT+ V  S  +       D+EL  +C YD+L+++ 
Sbjct: 1855 NIVGTHGKIATPFWPGNYPLNSNYRWTVNVDSSHIIHGRILEMDIELTTNCFYDSLKIYD 1914

Query: 500  GSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLL-WYSGRATSGTEHQF 676
            G     + +G +CGT R +   +  N +T + +SD    GRGFLL W++   ++ T    
Sbjct: 1915 GFDIHSRLIGTYCGTQRES-FSSSRNSLTFQFSSDSSKSGRGFLLEWFAVDVSNVTLPTI 1973

Query: 677  ----CGGRLEKAQGTL--TTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSY 838
                CGG +      +   +P WP   Y  G  C W II  PD  + L     D+E    
Sbjct: 1974 APGACGGYMVTGDTPVFFFSPGWP-GPYGNGADCIW-IIYAPDSTVELNILSMDIEAQLS 2031

Query: 839  CRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYR 1015
            C YD + + +G  S  +++L   CG   PGPI S G  + ++F SD SVT  GF+AS++
Sbjct: 2032 CSYDKLIIKDGD-SRLSQQLAVLCGRSVPGPIRSTGEYMYIRFTSDGSVTGAGFNASFQ 2089



 Score =  125 bits (313), Expect = 1e-28
 Identities = 72/237 (30%), Positives = 117/237 (49%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG++ GE G + S  +PN Y   + C WTI+ P  + V L+F  F +    SC  D +E
Sbjct: 817  CGGELRGE-GVIRSPFYPNAYAGRRTCRWTISQPPREVVLLNFTDFQIGSSSSCDTDYIE 875

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            +   S        +FCGT  P+ + +  N + +          RGF+  +S      +E 
Sbjct: 876  IGPSSVLGSPGNEKFCGTNIPSFITSVYNVLYVTFVKSSSMENRGFMAMFS------SEK 929

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CG  L ++ G + +P  P + YP G++C+WHI+    Q+I L F  F LE    C  D
Sbjct: 930  LECGKVLTESTGIIESPGHP-NVYPSGVNCTWHIVVQRGQLIRLVFSSFYLEFHYNCAND 988

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTL 1021
             + V++         LG++CG   P  ++S  + + + FVSD ++  +GFS +Y  +
Sbjct: 989  YLEVYDTIAQTS---LGRYCGKSIPPSLTSSSHSIKLIFVSDSALAHEGFSINYEAI 1042



 Score =  123 bits (309), Expect = 3e-28
 Identities = 71/224 (31%), Positives = 114/224 (50%), Gaps = 2/224 (0%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG++T  +G L S  +P  Y  + EC W +         L F+ F LE HP+C  D L 
Sbjct: 1165 CGGNLTTPTGVLTSPNYPMPYYHSSECYWRLEASRGSPFLLEFQDFHLEHHPNCSLDYLA 1224

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            VF G  T+ + + + CG   PAP+ +  + V L++ +D G  GRGF + Y          
Sbjct: 1225 VFDGPSTNSRLINKLCGDTPPAPIRSSKDIVLLKLRTDAGQQGRGFEINY---------R 1275

Query: 671  QFCGG--RLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCR 844
            Q C     + K  G L + N+P + Y     C+W I A     ++ TF +FD+E    C 
Sbjct: 1276 QTCDNVVIVNKTSGILESINYP-NPYDKDQRCNWTIQATTGNTVNYTFLEFDVENYVNCS 1334

Query: 845  YDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSD 976
             D + +++G      +R+G++CG+  P P ++ G++L+V F +D
Sbjct: 1335 TDYLELYDG-----PQRIGRYCGENIPPPGATTGSKLIVVFHTD 1373



 Score =  123 bits (308), Expect = 5e-28
 Identities = 81/254 (31%), Positives = 123/254 (48%), Gaps = 12/254 (4%)
 Frame = +2

Query: 311  CGGD-VTGESG-YLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDA 484
            CGG  VTG++  +  S G+P  Y    +CIW I  P+S TV L+    D+E   SC YD 
Sbjct: 1978 CGGYMVTGDTPVFFFSPGWPGPYGNGADCIWIIYAPDS-TVELNILSMDIEAQLSCSYDK 2036

Query: 485  LEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGT 664
            L +  G     Q+L   CG   P P+ + G  + +R TSD    G GF         + +
Sbjct: 2037 LIIKDGDSRLSQQLAVLCGRSVPGPIRSTGEYMYIRFTSDGSVTGAGF---------NAS 2087

Query: 665  EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGK-FDLE-PDSY 838
              + CGG L   +G +T+P +P+ +Y P ++CSWH++      I++ F + F ++  DS 
Sbjct: 2088 FQKSCGGYLHADRGIITSPKYPD-NYLPNLNCSWHVLVQSGLTIAVHFEQPFQIQNRDSS 2146

Query: 839  CRYDSVSVFNGAVSDDAKRL------GKFCGDKAPGPISSEGNELLVQFVSDLSVTADGF 1000
            C      V      + +  L      G+FCG   P  + +  NE+ +QF+SD S    GF
Sbjct: 2147 CSQGDYLVLRNGPDNHSPPLGPSGGNGRFCGIYTPSTLFTSDNEMFIQFISDNSNGGQGF 2206

Query: 1001 SASY--RTLPRGAT 1036
               Y  ++L  G T
Sbjct: 2207 KIRYEAKSLACGGT 2220



 Score =  121 bits (304), Expect = 1e-27
 Identities = 79/236 (33%), Positives = 113/236 (47%), Gaps = 2/236 (0%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPN-LYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            CGG V+G+SG + S G+P  LY  N  C W I       +++ F  F+L+  P C  D +
Sbjct: 2336 CGGTVSGDSGVIESVGYPTRLYANNVFCQWHIQGLPGHYLTIRFEDFNLQSSPGCAKDFV 2395

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTE 667
            E++    TSG  LGR+CG   P+ +    N  ++R  +D      GF L +       + 
Sbjct: 2396 EIWENH-TSGILLGRYCGNSIPSSVDTSSNVASIRFVTDGSVTDSGFRLQFK------SS 2448

Query: 668  HQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRY 847
             + CGG L    GT T+PN+P  +  P I C W I     + I LTF    L     C  
Sbjct: 2449 REVCGGDLHGPTGTFTSPNYPNPNPHPRI-CEWTINVHEGRQIILTFTNLRLSTQQSCNT 2507

Query: 848  DSVSVFNGAVSDDAKRLGKFCGD-KAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
            + + VFNG + +++ RL K C          S GN + V F +D S    GF+ASY
Sbjct: 2508 EHLIVFNG-IRNNSPRLQKLCSRVNVTNEFKSSGNTMKVIFFTDGSRPYGGFTASY 2562



 Score =  120 bits (302), Expect = 2e-27
 Identities = 70/254 (27%), Positives = 116/254 (45%), Gaps = 5/254 (1%)
 Frame = +2

Query: 272  QGQTPNYTRPVFLCGGDV----TGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSF 439
            QG    Y      CGG +        GY+ S  +P  YP + ECIW +  P  +++ L F
Sbjct: 2204 QGFKIRYEAKSLACGGTIYIHDANSDGYVTSPNYPANYPQHAECIWILEAPSGRSIQLQF 2263

Query: 440  R-VFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTG 616
               F++E  P+C    LE+  G+ ++   L + CG   P   V+    + L+  ++ G+G
Sbjct: 2264 EDQFNIEETPNCSASYLELRDGANSNAPVLSKLCGHTLPRNWVSSRGLMYLKFHTEGGSG 2323

Query: 617  GRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVI 796
              GF   YS  +        CGG +    G + +  +P   Y   + C WHI   P   +
Sbjct: 2324 YMGFKAKYSIVS--------CGGTVSGDSGVIESVGYPTRLYANNVFCQWHIQGLPGHYL 2375

Query: 797  SLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSD 976
            ++ F  F+L+    C  D V ++    S     LG++CG+  P  + +  N   ++FV+D
Sbjct: 2376 TIRFEDFNLQSSPGCAKDFVEIWENHTS--GILLGRYCGNSIPSSVDTSSNVASIRFVTD 2433

Query: 977  LSVTADGFSASYRT 1018
             SVT  GF   +++
Sbjct: 2434 GSVTDSGFRLQFKS 2447



 Score =  115 bits (288), Expect = 9e-26
 Identities = 68/239 (28%), Positives = 112/239 (46%), Gaps = 1/239 (0%)
 Frame = +2

Query: 287  NYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHP 466
            ++T  +  C  +     G L S G+P  Y  N +C   +  P++  +SL F  F LE   
Sbjct: 3387 HFTYEIADCNREYNQAFGNLKSPGWPQGYANNLDCSIILRAPQNHRISLFFYWFQLEDSR 3446

Query: 467  SCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSG 646
             C  D LEV  GS +S   LG++C    P P+ +  N++ L   SD+     G+ + ++ 
Sbjct: 3447 QCMNDFLEVRNGSSSSSPLLGKYCSNLLPNPIFSQSNELYLHFHSDDSDTHHGYEIIWAS 3506

Query: 647  RATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLE 826
              T       CGG L   +G L  P +P+S YP    C W I+AP  + +S+ F    ++
Sbjct: 3507 SPTG------CGGTLLGNEGILANPGFPDS-YPNNTHCEWTIVAPSGRPLSVGFPFLSID 3559

Query: 827  PDSYCRYDSVSVFNGAVSDDAKRLGKFCG-DKAPGPISSEGNELLVQFVSDLSVTADGF 1000
                C  + + +FNG    ++   G FCG D    P  +  N + ++F ++ +  + GF
Sbjct: 3560 SPGGCDQNYLILFNGP-DANSPPFGPFCGIDTVVAPFHASSNRVFIRFHAEYATVSSGF 3617



 Score =  112 bits (280), Expect = 8e-25
 Identities = 79/253 (31%), Positives = 115/253 (45%), Gaps = 4/253 (1%)
 Frame = +2

Query: 269  AQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVF 448
            AQG + ++   +  CG      +G + S  FP  Y  N  C + I V     V L+F  F
Sbjct: 2909 AQGFSASF---ISRCGRTFNSSTGDIVSPNFPKHYDNNMNCNYYIDVAPQSLVILTFVSF 2965

Query: 449  DLE----LHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTG 616
             LE    +  +C YD L +  G   S   L   CG+    PL   G  V L   SD    
Sbjct: 2966 HLEDRSAVSGTCDYDGLHIIKGHNLSSTPLVTICGSETLRPLTIDG-PVMLNFYSDAYIT 3024

Query: 617  GRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVI 796
              GF + Y  R  +      CGG      G L +P++  ++YP  + C + +    D++I
Sbjct: 3025 DFGFKISY--RVAN------CGGIYSGTYGVLNSPSFSYTNYPNNVYCVYSLQVRNDRLI 3076

Query: 797  SLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSD 976
             L F  F++ P + C +D + VF+G  S   + +GKFCG   P  I S  N L + F +D
Sbjct: 3077 LLRFNDFEIVPSNLCSHDYLEVFDGP-SIGNRSIGKFCGSTLPQVIKSTNNSLTLLFKTD 3135

Query: 977  LSVTADGFSASYR 1015
             S TA G+  S+R
Sbjct: 3136 SSQTARGWKVSFR 3148



 Score =  111 bits (278), Expect = 1e-24
 Identities = 78/234 (33%), Positives = 111/234 (47%), Gaps = 2/234 (0%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +T  +G + S G PN+YP    C W I V   Q + L F  F LE H +C  D LE
Sbjct: 932  CGKVLTESTGIIESPGHPNVYPSGVNCTWHIVVQRGQLIRLVFSSFYLEFHYNCANDYLE 991

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V+     +   LGR+CG   P  L +  + + L   SD      GF + Y     S    
Sbjct: 992  VY--DTIAQTSLGRYCGKSIPPSLTSSSHSIKLIFVSDSALAHEGFSINYEAINASSV-- 1047

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEP--DSYCR 844
              C        G L++PN+P ++YP   +C + I    +Q I+L F  F LE      C 
Sbjct: 1048 --CLYDYTDNFGRLSSPNFP-NNYPHNWNCVYRITVGLNQQIALHFTDFALEDYFGPKC- 1103

Query: 845  YDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSA 1006
             D V + +G   + +  +G +CG   P  I S  N+L ++F SD ++TA GFSA
Sbjct: 1104 VDFVEIRDGGF-ETSPLIGIYCGSVFPPRIISHSNKLWLRFKSDTALTARGFSA 1156



 Score =  108 bits (269), Expect = 2e-23
 Identities = 68/248 (27%), Positives = 103/248 (41%)
 Frame = +2

Query: 272  QGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFD 451
            +G T  +   +  CGG +TG  G + S G+P  YPP ++C+W + V     ++ +F    
Sbjct: 577  RGFTARWEAKLPECGGILTGNYGSITSPGYPGNYPPGRDCVWNLLVSPGSLITFTFGTLS 636

Query: 452  LELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFL 631
            LE H  C  D LE+  G       LG+FC +    PL   G    +   SD  T  +GF 
Sbjct: 637  LESHNDCSKDYLEIRDGPFHHDPILGKFCTSLSTPPLQTTGPAARIHFHSDSETSDKGFH 696

Query: 632  LWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFG 811
            + Y     +     +CGG     +G L  P      +     C + I  P  + I + F 
Sbjct: 697  ITY----LTTPSDLYCGGNYTDTEGELLLPPL-TGPFSHSRQCVYLISQPQGEQIVINFT 751

Query: 812  KFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTA 991
              +LE    C +  +      V D    L K CG++   PI S  N + ++   D  V  
Sbjct: 752  HVELESQRGCSHTFIE-----VGDHESLLRKICGNETLFPIRSISNNVWIRLRIDALVQK 806

Query: 992  DGFSASYR 1015
              F A Y+
Sbjct: 807  ASFRADYQ 814



 Score =  102 bits (255), Expect = 6e-22
 Identities = 69/238 (28%), Positives = 105/238 (44%), Gaps = 1/238 (0%)
 Frame = +2

Query: 290  YTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPS 469
            Y+     CGG      G   S G+P  Y  N EC+W I       + LSF  F LE   +
Sbjct: 1731 YSASTSACGGTFYTGDGIFNSPGYPEDYHSNTECVWNIASSPGNHLQLSFLSFQLENSLN 1790

Query: 470  CRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVA-PGNQVTLRMTSDEGTGGRGFLLWYSG 646
            C  D +E+  G+ T G  +GR+CG   P    +  G+ + +R  SD    G GF   +  
Sbjct: 1791 CNKDFVEIREGNAT-GHLMGRYCGNSLPGNYSSIEGHNLWVRFVSDGSGTGMGFQARF-- 1847

Query: 647  RATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLE 826
                  ++ F    +    G + TP WP  +YP   +  W +      +I     + D+E
Sbjct: 1848 ------KNIFGNDNIVGTHGKIATPFWP-GNYPLNSNYRWTVNVDSSHIIHGRILEMDIE 1900

Query: 827  PDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGF 1000
              + C YDS+ +++G     ++ +G +CG +     SS  N L  QF SD S +  GF
Sbjct: 1901 LTTNCFYDSLKIYDG-FDIHSRLIGTYCGTQRES-FSSSRNSLTFQFSSDSSKSGRGF 1956



 Score =  100 bits (248), Expect = 4e-21
 Identities = 73/257 (28%), Positives = 121/257 (47%), Gaps = 15/257 (5%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSF-RVFDLELHPSC--RYD 481
            CGG +  + G + S  +P+ Y PN  C W + V    T+++ F + F ++   S   + D
Sbjct: 2092 CGGYLHADRGIITSPKYPDNYLPNLNCSWHVLVQSGLTIAVHFEQPFQIQNRDSSCSQGD 2151

Query: 482  ALEVFAGS-------GTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY 640
             L +  G        G SG   GRFCG + P+ L    N++ ++  SD   GG+GF + Y
Sbjct: 2152 YLVLRNGPDNHSPPLGPSGGN-GRFCGIYTPSTLFTSDNEMFIQFISDNSNGGQGFKIRY 2210

Query: 641  SGRATSGTEHQFCGGRL----EKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTF 808
              ++ +      CGG +      + G +T+PN+P ++YP    C W + AP  + I L F
Sbjct: 2211 EAKSLA------CGGTIYIHDANSDGYVTSPNYP-ANYPQHAECIWILEAPSGRSIQLQF 2263

Query: 809  -GKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSV 985
              +F++E    C    + + +GA + +A  L K CG   P    S    + ++F ++   
Sbjct: 2264 EDQFNIEETPNCSASYLELRDGA-NSNAPVLSKLCGHTLPRNWVSSRGLMYLKFHTEGGS 2322

Query: 986  TADGFSASYRTLPRGAT 1036
               GF A Y  +  G T
Sbjct: 2323 GYMGFKAKYSIVSCGGT 2339



 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 80/261 (30%), Positives = 114/261 (43%), Gaps = 8/261 (3%)
 Frame = +2

Query: 272  QGQTPNYTRPVFLCGG--DVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRV 445
            +G    YT     CGG  + T      +S    N+  P   C W I  P  Q V ++  V
Sbjct: 3265 RGFNATYTFVDMPCGGTYNATSMPQNTSSPQLSNIRRPFSTCTWVIEAPPHQQVQIT--V 3322

Query: 446  FDLELHPS--CRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGG 619
            + L+L PS  C   +LE+     T+G ++ +FCG           N  TL +    G+  
Sbjct: 3323 WKLQL-PSQDCSRSSLELQDSEQTNGNQVTQFCGA----------NYTTLPVFYSSGSTA 3371

Query: 620  ----RGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPD 787
                +   L  + R     E   C     +A G L +P WP+  Y   + CS  + AP +
Sbjct: 3372 VVVFKSDFLNRNSRVHFTYEIADCNREYNQAFGNLKSPGWPQG-YANNLDCSIILRAPQN 3430

Query: 788  QVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQF 967
              ISL F  F LE    C  D + V NG+ S  +  LGK+C +  P PI S+ NEL + F
Sbjct: 3431 HRISLFFYWFQLEDSRQCMNDFLEVRNGS-SSSSPLLGKYCSNLLPNPIFSQSNELYLHF 3489

Query: 968  VSDLSVTADGFSASYRTLPRG 1030
             SD S T  G+   + + P G
Sbjct: 3490 HSDDSDTHHGYEIIWASSPTG 3510



 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 68/241 (28%), Positives = 101/241 (41%), Gaps = 6/241 (2%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGGD+ G +G   S  +PN  P  + C WTI V E + + L+F    L    SC  + L
Sbjct: 2451 VCGGDLHGPTGTFTSPNYPNPNPHPRICEWTINVHEGRQIILTFTNLRLSTQQSCNTEHL 2510

Query: 488  EVFAGSGTSGQRLGRFCGTFRPA-PLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGT 664
             VF G   +  RL + C          + GN + +   +D      GF   Y     + +
Sbjct: 2511 IVFNGIRNNSPRLQKLCSRVNVTNEFKSSGNTMKVIFFTDGSRPYGGFTASY-----TSS 2565

Query: 665  EHQFCGGRLEKAQ-GTLTTPNWPE-SDYPPGISCSWHIIAP--PDQVISLTFGKFDLEPD 832
            E   CGG L     G  ++P +    DY   + C W +  P   +  IS+ F    LE  
Sbjct: 2566 EDAVCGGTLPSVSGGNFSSPGYNGIRDYARNLDCEWTLSNPNRENSSISIHFLGLSLESH 2625

Query: 833  SYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG-PISSEGNELLVQFVSDLSVTADGFSAS 1009
              C +D +    G  + D   + KFC   AP  P+     ++ + FVS+  V   GF   
Sbjct: 2626 QDCTFDVLEFRVG--NADGPLIEKFCSLSAPRVPLVIPYPQVWIHFVSNERVEYTGFYVE 2683

Query: 1010 Y 1012
            Y
Sbjct: 2684 Y 2684


>ref|NP_001070875.1| neuropilin-2 isoform 6 precursor [Mus musculus].
          Length = 901

 Score =  143 bits (360), Expect = 4e-34
 Identities = 84/259 (32%), Positives = 131/259 (50%), Gaps = 9/259 (3%)
 Frame = +2

Query: 311  CGGDVTG-ESGYLASEGFPNLYPPNKECIWTITVPE-SQTVSLSFRV-FDLELHPSCRYD 481
            CGG +   ++GY+ S G+P  YP ++ C W +  PE +Q + L+F   F++E H  C+YD
Sbjct: 28   CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYD 86

Query: 482  ALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSG 661
             +E+  G   S   LG+ CG   P  +++ G+ + ++ TSD    G GF L Y    T  
Sbjct: 87   FIEIRDGDSESADLLGKHCGNIAPPTIISSGSVLYIKFTSDYARQGAGFSLRYEIFKTGS 146

Query: 662  TEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSY- 838
             +   C        GT+ +P +PE  YP  + C++ I+A P   I L F  FDLE D   
Sbjct: 147  ED---CSKNFTSPNGTIESPGFPEK-YPHNLDCTFTILAKPRMEIILQFLTFDLEHDPLQ 202

Query: 839  -----CRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFS 1003
                 C+YD + +++G +      +GK+CG K P  + S    L + F +D++V  DGFS
Sbjct: 203  VGEGDCKYDWLDIWDG-IPHVGPLIGKYCGTKTPSKLRSSTGILSLTFHTDMAVAKDGFS 261

Query: 1004 ASYRTLPRGATEKAPAQSP 1060
            A Y  + +   E      P
Sbjct: 262  ARYYLIHQEPPENFQCNVP 280



 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 52/139 (37%), Positives = 76/139 (54%), Gaps = 3/139 (2%)
 Frame = +2

Query: 632  LWYSGRATSGTEHQFCGGRLE-KAQGTLTTPNWPESDYPPGISCSWHIIAP-PDQVISLT 805
            L++SG      +   CGGRL  K  G +T+P +P+ DYP   +C W + AP P+Q I L 
Sbjct: 13   LYFSGHEVRSQQDPPCGGRLNSKDAGYITSPGYPQ-DYPSHQNCEWIVYAPEPNQKIVLN 71

Query: 806  FG-KFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLS 982
            F   F++E    C+YD + + +G  S+ A  LGK CG+ AP  I S G+ L ++F SD +
Sbjct: 72   FNPHFEIEKHD-CKYDFIEIRDGD-SESADLLGKHCGNIAPPTIISSGSVLYIKFTSDYA 129

Query: 983  VTADGFSASYRTLPRGATE 1039
                GFS  Y     G+ +
Sbjct: 130  RQGAGFSLRYEIFKTGSED 148


>ref|NP_001070874.1| neuropilin-2 isoform 5 precursor [Mus musculus].
          Length = 906

 Score =  143 bits (360), Expect = 4e-34
 Identities = 84/259 (32%), Positives = 131/259 (50%), Gaps = 9/259 (3%)
 Frame = +2

Query: 311  CGGDVTG-ESGYLASEGFPNLYPPNKECIWTITVPE-SQTVSLSFRV-FDLELHPSCRYD 481
            CGG +   ++GY+ S G+P  YP ++ C W +  PE +Q + L+F   F++E H  C+YD
Sbjct: 28   CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYD 86

Query: 482  ALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSG 661
             +E+  G   S   LG+ CG   P  +++ G+ + ++ TSD    G GF L Y    T  
Sbjct: 87   FIEIRDGDSESADLLGKHCGNIAPPTIISSGSVLYIKFTSDYARQGAGFSLRYEIFKTGS 146

Query: 662  TEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSY- 838
             +   C        GT+ +P +PE  YP  + C++ I+A P   I L F  FDLE D   
Sbjct: 147  ED---CSKNFTSPNGTIESPGFPEK-YPHNLDCTFTILAKPRMEIILQFLTFDLEHDPLQ 202

Query: 839  -----CRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFS 1003
                 C+YD + +++G +      +GK+CG K P  + S    L + F +D++V  DGFS
Sbjct: 203  VGEGDCKYDWLDIWDG-IPHVGPLIGKYCGTKTPSKLRSSTGILSLTFHTDMAVAKDGFS 261

Query: 1004 ASYRTLPRGATEKAPAQSP 1060
            A Y  + +   E      P
Sbjct: 262  ARYYLIHQEPPENFQCNVP 280



 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 52/139 (37%), Positives = 76/139 (54%), Gaps = 3/139 (2%)
 Frame = +2

Query: 632  LWYSGRATSGTEHQFCGGRLE-KAQGTLTTPNWPESDYPPGISCSWHIIAP-PDQVISLT 805
            L++SG      +   CGGRL  K  G +T+P +P+ DYP   +C W + AP P+Q I L 
Sbjct: 13   LYFSGHEVRSQQDPPCGGRLNSKDAGYITSPGYPQ-DYPSHQNCEWIVYAPEPNQKIVLN 71

Query: 806  FG-KFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLS 982
            F   F++E    C+YD + + +G  S+ A  LGK CG+ AP  I S G+ L ++F SD +
Sbjct: 72   FNPHFEIEKHD-CKYDFIEIRDGD-SESADLLGKHCGNIAPPTIISSGSVLYIKFTSDYA 129

Query: 983  VTADGFSASYRTLPRGATE 1039
                GFS  Y     G+ +
Sbjct: 130  RQGAGFSLRYEIFKTGSED 148


  Database: RefSeq49_MP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 15,617,559
  Number of sequences in database:  30,036
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 30036
Number of Hits to DB: 56,232,628
Number of extensions: 1837360
Number of successful extensions: 9976
Number of sequences better than 1.0e-05: 53
Number of HSP's gapped: 9539
Number of HSP's successfully gapped: 231
Length of query: 520
Length of database: 15,617,559
Length adjustment: 106
Effective length of query: 414
Effective length of database: 12,433,743
Effective search space: 5147569602
Effective search space used: 5147569602
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-002572
         (1561 letters)

Database: RefSeq49_SP.fasta 
           24,897 sequences; 11,343,932 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|XP_003354522.1| PREDICTED: procollagen C-endopeptidase enhan...   809   0.0  
Alignment   gi|XP_001928928.3| PREDICTED: procollagen C-endopeptidase enhan...   302   4e-82
Alignment   gi|XP_001928510.1| PREDICTED: tolloid-like protein 2 [Sus scrof...   167   2e-41
Alignment   gi|XP_003359075.1| PREDICTED: bone morphogenetic protein 1 isof...   167   2e-41
Alignment   gi|XP_003129040.2| PREDICTED: tolloid-like protein 1 [Sus scrof...   166   3e-41
Alignment   gi|XP_001927808.2| PREDICTED: bone morphogenetic protein 1 isof...   164   1e-40
Alignment   gi|XP_003356512.1| PREDICTED: CUB domain-containing protein 2-l...   160   2e-39
Alignment   gi|XP_003130846.1| PREDICTED: neuropilin-1 [Sus scrofa].             150   1e-36
Alignment   gi|XP_003361777.1| PREDICTED: CUB domain-containing protein 2-l...   144   1e-34
Alignment   gi|XP_003357786.1| PREDICTED: cubilin-like [Sus scrofa].             141   9e-34

>ref|XP_003354522.1| PREDICTED: procollagen C-endopeptidase enhancer 1 [Sus scrofa].
          Length = 470

 Score =  809 bits (2090), Expect = 0.0
 Identities = 399/453 (88%), Positives = 399/453 (88%)
 Frame = +2

Query: 203  MLPAATASXXXXXXXXXXXXXFAQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPN 382
            MLPAATAS             FAQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPN
Sbjct: 1    MLPAATASLLGPLLTAWALLPFAQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPN 60

Query: 383  KECIWTITVPESQTVSLSFRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPL 562
            KECIWTITVPESQTVSLSFRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPL
Sbjct: 61   KECIWTITVPESQTVSLSFRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPL 120

Query: 563  VAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDY 742
            VAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDY
Sbjct: 121  VAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDY 180

Query: 743  PPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKA 922
            PPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKA
Sbjct: 181  PPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKA 240

Query: 923  PGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGATEKAPAQSPGEDARXXXXXXXXX 1102
            PGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGATEKAPAQSPGEDAR         
Sbjct: 241  PGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGATEKAPAQSPGEDARPSPPLLGPG 300

Query: 1103 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSDGPSVPCPKQCRRTGTLQSNFCNSNLVV 1282
                                          GSDGPSVPCPKQCRRTGTLQSNFCNSNLVV
Sbjct: 301  PKPGAGPKVKPELPPEEKPKAAPKAEATPAGSDGPSVPCPKQCRRTGTLQSNFCNSNLVV 360

Query: 1283 TATVKSMVRGPGEGLTVTVSLIGVYKTGGLDLPSPPTDTSLKFYAPCKQCPPMKKGTSYL 1462
            TATVKSMVRGPGEGLTVTVSLIGVYKTGGLDLPSPPTDTSLKFYAPCKQCPPMKKGTSYL
Sbjct: 361  TATVKSMVRGPGEGLTVTVSLIGVYKTGGLDLPSPPTDTSLKFYAPCKQCPPMKKGTSYL 420

Query: 1463 MMGQVDENRGPILPPESFVVLYRPNQGQILTKL 1561
            MMGQVDENRGPILPPESFVVLYRPNQ QILT L
Sbjct: 421  MMGQVDENRGPILPPESFVVLYRPNQDQILTNL 453


>ref|XP_001928928.3| PREDICTED: procollagen C-endopeptidase enhancer 2 [Sus scrofa].
          Length = 479

 Score =  302 bits (773), Expect = 4e-82
 Identities = 159/392 (40%), Positives = 229/392 (58%), Gaps = 2/392 (0%)
 Frame = +2

Query: 392  IWTITVPESQTVSLSFRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAP 571
            ++T  VPE + V L+FR  DLE    CRYD ++V+ G   +GQR+GRFCGTFRP  LV+ 
Sbjct: 124  LFTQIVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNGHA-NGQRIGRFCGTFRPGALVSS 182

Query: 572  GNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPG 751
            GN++ ++M SD  T G GF+  ++    +    ++CGGRLE+  G+  TPNWP+ DYP G
Sbjct: 183  GNKMMVQMISDANTAGNGFMAMFTAAEPNERGDRYCGGRLERPSGSFKTPNWPDRDYPAG 242

Query: 752  ISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGP 931
            ++C WHI+AP +Q+I L F KFD+E D+YCRYD V+VFNG   +DA+R+GK+CGD  P P
Sbjct: 243  VACVWHIVAPKNQLIELEFEKFDVERDNYCRYDYVAVFNGGEINDAERIGKYCGDSPPAP 302

Query: 932  ISSEGNELLVQFVSDLSVTADGFSASYRTLPRG-ATEKAPAQSPGEDARXXXXXXXXXXX 1108
            I SE NELL+QF+SDLS+TADGF   Y+  P+   T  AP  +                 
Sbjct: 303  IVSERNELLIQFLSDLSLTADGFIGHYKFRPKKLPTTIAPPVT----------------- 345

Query: 1109 XXXXXXXXXXXXXXXXXXXXXXXXXXXXGSDGPSVPCPKQ-CRRTGTLQSNFCNSNLVVT 1285
                                         S  P+V   +Q C+RTGT +SN+C+SN V+ 
Sbjct: 346  ----------------------TTYPVTTSVKPTVALCQQKCKRTGTPESNYCSSNFVLA 383

Query: 1286 ATVKSMVRGPGEGLTVTVSLIGVYKTGGLDLPSPPTDTSLKFYAPCKQCPPMKKGTSYLM 1465
             TV + +   G  L  T+S+I +YK G L +     + S K    CKQCP +++G +Y++
Sbjct: 384  GTVITTI-PRGGSLHATISIINIYKEGNLAVQQAGKNMSAKVIVVCKQCPLLRRGLNYII 442

Query: 1466 MGQVDENRGPILPPESFVVLYRPNQGQILTKL 1561
            MGQV E+    + P SF+++++    ++L  L
Sbjct: 443  MGQVGEDGRGRIMPNSFIMMFKTKNQKLLNAL 474



 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 40/115 (34%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNL-YPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
           CGG +   SG   +  +P+  YP    C+W I  P++Q + L F  FD+E    CRYD +
Sbjct: 218 CGGRLERPSGSFKTPNWPDRDYPAGVACVWHIVAPKNQLIELEFEKFDVERDNYCRYDYV 277

Query: 488 EVF-AGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGR 649
            VF  G     +R+G++CG   PAP+V+  N++ ++  SD      GF+  Y  R
Sbjct: 278 AVFNGGEINDAERIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHYKFR 332


>ref|XP_001928510.1| PREDICTED: tolloid-like protein 2 [Sus scrofa].
          Length = 1020

 Score =  167 bits (422), Expect = 2e-41
 Identities = 92/268 (34%), Positives = 135/268 (50%), Gaps = 34/268 (12%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGGD+  ++G + S  +P+ Y P+KEC+W ITV E   V LSF+ F++E H SC YD LE
Sbjct: 469  CGGDINKDAGQIQSPNYPDDYRPSKECVWKITVSEGFHVGLSFQAFEIERHDSCAYDYLE 528

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLL----------W- 637
            +  G       +G FCG  +P  + +  N++ ++  SD      GF            W 
Sbjct: 529  IRDGPTEESALIGHFCGYEKPEDVKSSSNRMWMKFVSDGSINKAGFAANFFKEVDECSWP 588

Query: 638  -----------------------YSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPP 748
                                   Y   A        CGG + K  GT+T+P WP+ +YP 
Sbjct: 589  DHGGCEQRCVNTLGSYKCVCDPGYELAADKKACEVACGGFITKLNGTITSPGWPK-EYPT 647

Query: 749  GISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG 928
              +C W ++AP    ISL F  F+LE +  C+YD V V +G +S DA+  GKFCG + P 
Sbjct: 648  NKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSG-LSPDARLHGKFCGSEMPE 706

Query: 929  PISSEGNELLVQFVSDLSVTADGFSASY 1012
             I+S+ N + ++F SD +V+  GF A +
Sbjct: 707  VITSQSNNMRLEFKSDNTVSKRGFRAHF 734



 Score =  163 bits (412), Expect = 3e-40
 Identities = 87/270 (32%), Positives = 131/270 (48%), Gaps = 34/270 (12%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG +T  +G + S G+P  YP NK C+W +  P    +SL F VF+LE +  C+YD +E
Sbjct: 625  CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 684

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY------SGRA 652
            V +G     +  G+FCG+  P  + +  N + L   SD     RGF   +        + 
Sbjct: 685  VRSGLSPDARLHGKFCGSEMPEVITSQSNNMRLEFKSDNTVSKRGFRAHFFSDKDECAKD 744

Query: 653  TSGTEHQF----------------------------CGGRLEKAQGTLTTPNWPESDYPP 748
              G +H+                             C  ++  A+GTL +PNWP+  YP 
Sbjct: 745  NGGCQHECVNTVGSYLCRCRNGYRLHENQQDCKEAGCAHKISSAEGTLVSPNWPDK-YPS 803

Query: 749  GISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG 928
               C+W+I +     + LTF +F++E    C YD + +++G  S  A  LG+FCG K P 
Sbjct: 804  RRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLELYDGPDSL-APVLGRFCGSKKPD 862

Query: 929  PISSEGNELLVQFVSDLSVTADGFSASYRT 1018
            P+ + GN L ++F SD SV   GF A + T
Sbjct: 863  PVVASGNSLFLRFYSDASVQRRGFQAMHST 892



 Score =  147 bits (372), Expect = 1e-35
 Identities = 81/237 (34%), Positives = 123/237 (51%), Gaps = 3/237 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   ++   G L S  +P+ YP  +EC W I+      V L+F  F++E H  C YD LE
Sbjct: 781  CAHKISSAEGTLVSPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLE 840

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            ++ G  +    LGRFCG+ +P P+VA GN + LR  SD     RGF      +A   TE 
Sbjct: 841  LYDGPDSLAPVLGRFCGSKKPDPVVASGNSLFLRFYSDASVQRRGF------QAMHSTE- 893

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGGRL+   + +   +   + +++YP    C W I+A     + L F  F++E ++ C
Sbjct: 894  --CGGRLKAEVQTKELYSHAQFGDNNYPSQARCDWVIVAEDGYGVELIFRTFEVEEEADC 951

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             YD +  ++G     A RLG+FCG      I S G+ L+++F +D ++   GF A Y
Sbjct: 952  GYDYMEAYDG-YDSTAPRLGRFCGSGPLEEIYSAGDSLMIRFHTDDTINKKGFHARY 1007



 Score =  139 bits (349), Expect = 6e-33
 Identities = 75/234 (32%), Positives = 115/234 (49%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G  ++ GFPN YP    C+W I+V   + + L+F   DL     C YD +E
Sbjct: 356  CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 415

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G       LGRFCG   P PL++  +++ +   S     G+GF   Y          
Sbjct: 416  VRDGYWRKAPLLGRFCGDKIPEPLISTDSRLWVEFRSSSNILGKGFFAVYEAT------- 468

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG + K  G + +PN+P+ DY P   C W I       + L+F  F++E    C YD
Sbjct: 469  --CGGDINKDAGQIQSPNYPD-DYRPSKECVWKITVSEGFHVGLSFQAFEIERHDSCAYD 525

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + + +G   + A  +G FCG + P  + S  N + ++FVSD S+   GF+A++
Sbjct: 526  YLEIRDGPTEESA-LIGHFCGYEKPEDVKSSSNRMWMKFVSDGSINKAGFAANF 578



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 45/126 (35%), Positives = 56/126 (44%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+   G  + P +P   YP    C W I   P + I L F   DL     C YD V
Sbjct: 356  CGETLQDTTGNFSAPGFPNG-YPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 414

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G     A  LG+FCGDK P P+ S  + L V+F S  ++   GF A Y     G  
Sbjct: 415  EVRDGYWRK-APLLGRFCGDKIPEPLISTDSRLWVEFRSSSNILGKGFFAVYEATCGGDI 473

Query: 1037 EKAPAQ 1054
             K   Q
Sbjct: 474  NKDAGQ 479



 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
 Frame = +2

Query: 311  CGG----DVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG    +V  +  Y  ++   N YP    C W I   +   V L FR F++E    C Y
Sbjct: 894  CGGRLKAEVQTKELYSHAQFGDNNYPSQARCDWVIVAEDGYGVELIFRTFEVEEEADCGY 953

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYS 643
            D +E + G  ++  RLGRFCG+     + + G+ + +R  +D+    +GF   Y+
Sbjct: 954  DYMEAYDGYDSTAPRLGRFCGSGPLEEIYSAGDSLMIRFHTDDTINKKGFHARYT 1008


>ref|XP_003359075.1| PREDICTED: bone morphogenetic protein 1 isoform 2 [Sus scrofa].
          Length = 737

 Score =  167 bits (422), Expect = 2e-41
 Identities = 98/285 (34%), Positives = 146/285 (51%), Gaps = 34/285 (11%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGGDV  ++G++ S  +P+ Y P+K CIW I V E   V L+F+ F++E H SC YD L
Sbjct: 441  ICGGDVKKDNGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYL 500

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY-------SG 646
            EV  G   S   +GR+CG  +P  + +  +++ L+  SD      GF + +       S 
Sbjct: 501  EVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR 560

Query: 647  RATSGTEHQF---------------------------CGGRLEKAQGTLTTPNWPESDYP 745
                G E +                            CGG L K  G++T+P WP+ +YP
Sbjct: 561  PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK-EYP 619

Query: 746  PGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAP 925
            P  +C W ++AP    ISL F  F+ E +  C+YD V V +G ++ D+K  GKFCG + P
Sbjct: 620  PNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSG-LTADSKLHGKFCGSEKP 678

Query: 926  GPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGATEKAPAQSP 1060
              I+S+ N + V+F SD +V+  GF A +       +EK PA  P
Sbjct: 679  EVITSQYNNMRVEFKSDNTVSKKGFKAHF------FSEKRPALQP 717



 Score =  130 bits (327), Expect = 2e-30
 Identities = 73/234 (31%), Positives = 115/234 (49%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G  +S  +PN Y  +  C+W I+V   + + L+F   DL     C YD +E
Sbjct: 329  CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVE 388

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G        GRFCG   P P+V+  +++ +   S     G+GF   Y          
Sbjct: 389  VRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-------- 440

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG ++K  G + +PN+P+ DY P   C W I       + LTF  F++E    C YD
Sbjct: 441  -ICGGDVKKDNGHIQSPNYPD-DYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 498

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + V +G  S+ +  +G++CG + P  I S  + L ++FVSD S+   GF+ ++
Sbjct: 499  YLEVRDGH-SESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 551



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 40/115 (34%), Positives = 61/115 (53%)
 Frame = +2

Query: 284 PNYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELH 463
           P+  R    CGG +T  +G + S G+P  YPPNK CIW +  P    +SL F  F+ E +
Sbjct: 589 PDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGN 648

Query: 464 PSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGF 628
             C+YD +EV +G     +  G+FCG+ +P  + +  N + +   SD     +GF
Sbjct: 649 DVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF 703



 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 42/122 (34%), Positives = 56/122 (45%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+ + G  ++P +P   Y   + C W I   P + I L F   DL     C YD V
Sbjct: 329  CGETLQDSTGNFSSPEYPNG-YSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYV 387

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G       R G+FCG K P PI S  + L V+F S  +    GF A Y  +  G  
Sbjct: 388  EVRDGFWRKAPLR-GRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDV 446

Query: 1037 EK 1042
            +K
Sbjct: 447  KK 448


>ref|XP_003129040.2| PREDICTED: tolloid-like protein 1 [Sus scrofa].
          Length = 1013

 Score =  166 bits (421), Expect = 3e-41
 Identities = 91/269 (33%), Positives = 136/269 (50%), Gaps = 34/269 (12%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGG++    G + S  +P+ Y P KEC+W I V E   V L+F+ F++E H +C YD L
Sbjct: 461  ICGGEIRKNEGQIQSPNYPDDYRPMKECVWKIAVSEDCYVGLTFQAFEIERHDNCAYDYL 520

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGF------------- 628
            EV  G+  +   +GRFCG  +P  + +  N + ++  SD      GF             
Sbjct: 521  EVRDGNSENSPLIGRFCGYDKPEDIKSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAK 580

Query: 629  -------------LLWYSGRATSGTE--------HQFCGGRLEKAQGTLTTPNWPESDYP 745
                         L  Y      G E           CGG L K  GT+TTP WP+ +YP
Sbjct: 581  PDRGGCEQRCLNTLGSYQCSCEPGYELGPDKRTCEAACGGLLTKLNGTITTPGWPK-EYP 639

Query: 746  PGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAP 925
            P   C W ++AP    IS+ F  F+LE +  C+YD V +++G +S ++K  GKFCG + P
Sbjct: 640  PNKHCVWQVVAPTQYRISMKFEFFELEGNEVCKYDYVEIWSG-LSSESKLHGKFCGAEVP 698

Query: 926  GPISSEGNELLVQFVSDLSVTADGFSASY 1012
              I+S+ N + ++F SD +V+  GF A +
Sbjct: 699  EVITSQFNNMRIEFKSDNTVSKKGFKAHF 727



 Score =  153 bits (387), Expect = 2e-37
 Identities = 84/240 (35%), Positives = 130/240 (54%), Gaps = 3/240 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   +   SG++ S  +P+ YP  KEC W I+      V L+F  F++E H  C YD LE
Sbjct: 774  CEQKIHSPSGFITSPNWPDKYPSRKECTWEISATPGHRVKLAFSEFEIEQHQECAYDHLE 833

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            VF G       LGR CG   P P+VA GN++ +R  SD     +GF      +AT  TE 
Sbjct: 834  VFDGETEKSPILGRLCGNKIPEPIVATGNKMFVRFVSDASVQRKGF------QATHSTE- 886

Query: 671  QFCGGRL--EKAQGTL-TTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGGRL  E   G L +   + +++YP  + C W +++     + L+F  F++E ++ C
Sbjct: 887  --CGGRLKAESKPGDLYSHAQFGDNNYPGQVDCEWVLVSERGSRLELSFQIFEVEEEADC 944

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTL 1021
             YD V +F+G ++  A  LG+FCG   P  I+S G+ +L+ F +D +++  GF   Y+++
Sbjct: 945  GYDYVELFDG-LNSTAVGLGRFCGSGPPEEINSIGDTVLIHFHTDDTISKKGFHIRYKSI 1003



 Score =  145 bits (366), Expect = 6e-35
 Identities = 81/234 (34%), Positives = 118/234 (50%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G L+S GFPN YP    CIW ++V   + + L+F   DL     C YD +E
Sbjct: 349  CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTAGEKIVLNFTTMDLYKSSLCWYDYIE 408

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G       LGRFCG   P  L +  +++ +   S     G+GF   Y          
Sbjct: 409  VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAIYEA-------- 460

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG + K +G + +PN+P+ DY P   C W I    D  + LTF  F++E    C YD
Sbjct: 461  -ICGGEIRKNEGQIQSPNYPD-DYRPMKECVWKIAVSEDCYVGLTFQAFEIERHDNCAYD 518

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + V +G  S+++  +G+FCG   P  I S  N L ++FVSD +V   GF+A++
Sbjct: 519  YLEVRDGN-SENSPLIGRFCGYDKPEDIKSTSNTLWMKFVSDGTVNKAGFAANF 571



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 40/126 (31%), Positives = 61/126 (48%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+++ G L++P +P   YP    C W +     + I L F   DL   S C YD +
Sbjct: 349  CGETLQESNGNLSSPGFPNG-YPSYTHCIWRVSVTAGEKIVLNFTTMDLYKSSLCWYDYI 407

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G     +  LG+FCGDK P  ++S  + + ++F S  +    GF+A Y  +  G  
Sbjct: 408  EVRDGYWRK-SPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAIYEAICGGEI 466

Query: 1037 EKAPAQ 1054
             K   Q
Sbjct: 467  RKNEGQ 472



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 37/124 (29%), Positives = 61/124 (49%), Gaps = 4/124 (3%)
 Frame = +2

Query: 311  CGGDVTGESG----YLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG +  ES     Y  ++   N YP   +C W +       + LSF++F++E    C Y
Sbjct: 887  CGGRLKAESKPGDLYSHAQFGDNNYPGQVDCEWVLVSERGSRLELSFQIFEVEEEADCGY 946

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATS 658
            D +E+F G  ++   LGRFCG+  P  + + G+ V +   +D+    +GF + Y   +  
Sbjct: 947  DYVELFDGLNSTAVGLGRFCGSGPPEEINSIGDTVLIHFHTDDTISKKGFHIRYKSISYP 1006

Query: 659  GTEH 670
             T H
Sbjct: 1007 DTTH 1010


>ref|XP_001927808.2| PREDICTED: bone morphogenetic protein 1 isoform 1 [Sus scrofa].
          Length = 993

 Score =  164 bits (415), Expect = 1e-40
 Identities = 93/269 (34%), Positives = 140/269 (52%), Gaps = 34/269 (12%)
 Frame = +2

Query: 308  LCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            +CGGDV  ++G++ S  +P+ Y P+K CIW I V E   V L+F+ F++E H SC YD L
Sbjct: 441  ICGGDVKKDNGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYL 500

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY-------SG 646
            EV  G   S   +GR+CG  +P  + +  +++ L+  SD      GF + +       S 
Sbjct: 501  EVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR 560

Query: 647  RATSGTEHQF---------------------------CGGRLEKAQGTLTTPNWPESDYP 745
                G E +                            CGG L K  G++T+P WP+ +YP
Sbjct: 561  PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK-EYP 619

Query: 746  PGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAP 925
            P  +C W ++AP    ISL F  F+ E +  C+YD V V +G ++ D+K  GKFCG + P
Sbjct: 620  PNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSG-LTADSKLHGKFCGSEKP 678

Query: 926  GPISSEGNELLVQFVSDLSVTADGFSASY 1012
              I+S+ N + V+F SD +V+  GF A +
Sbjct: 679  EVITSQYNNMRVEFKSDNTVSKKGFKAHF 707



 Score =  157 bits (397), Expect = 2e-38
 Identities = 84/237 (35%), Positives = 126/237 (53%), Gaps = 3/237 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            C   VT  SG + S  +P+ YP  KEC W I+      V L+F   D+E  P C YD LE
Sbjct: 754  CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFLEMDIESQPECAYDHLE 813

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V+ G       LGRFCG+ +P P++A G+++ LR  SD     +GF      +A   TE 
Sbjct: 814  VYDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF------QAAHSTE- 866

Query: 671  QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
              CGG++    K +   +   + +++YP G+ C W I+A     + L F  F++E ++ C
Sbjct: 867  --CGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDC 924

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             YD + +F+G     A RLG++CG   P  + S G+ +LV+F SD ++T  GF   Y
Sbjct: 925  GYDYMELFDG-YDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 980



 Score =  154 bits (388), Expect = 2e-37
 Identities = 88/281 (31%), Positives = 133/281 (47%), Gaps = 36/281 (12%)
 Frame = +2

Query: 284  PNYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELH 463
            P+  R    CGG +T  +G + S G+P  YPPNK CIW +  P    +SL F  F+ E +
Sbjct: 589  PDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGN 648

Query: 464  PSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWY- 640
              C+YD +EV +G     +  G+FCG+ +P  + +  N + +   SD     +GF   + 
Sbjct: 649  DVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFF 708

Query: 641  -----------------------------SGRATSGTEHQF----CGGRLEKAQGTLTTP 721
                                         SG      +H      C  ++    GT+T+P
Sbjct: 709  SDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSP 768

Query: 722  NWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKR-- 895
            NWP+  YP    C+W I + P   + LTF + D+E    C YD + V++G    DAK   
Sbjct: 769  NWPDK-YPSKKECTWAISSTPGHRVKLTFLEMDIESQPECAYDHLEVYDGR---DAKAPV 824

Query: 896  LGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRT 1018
            LG+FCG K P P+ + G+ + ++F SD SV   GF A++ T
Sbjct: 825  LGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQAAHST 865



 Score =  130 bits (327), Expect = 2e-30
 Identities = 73/234 (31%), Positives = 115/234 (49%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CG  +   +G  +S  +PN Y  +  C+W I+V   + + L+F   DL     C YD +E
Sbjct: 329  CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVE 388

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G        GRFCG   P P+V+  +++ +   S     G+GF   Y          
Sbjct: 389  VRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-------- 440

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYD 850
              CGG ++K  G + +PN+P+ DY P   C W I       + LTF  F++E    C YD
Sbjct: 441  -ICGGDVKKDNGHIQSPNYPD-DYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 498

Query: 851  SVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
             + V +G  S+ +  +G++CG + P  I S  + L ++FVSD S+   GF+ ++
Sbjct: 499  YLEVRDGH-SESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 551



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 41/124 (33%), Positives = 61/124 (49%), Gaps = 4/124 (3%)
 Frame = +2

Query: 311  CGGDVTGESG----YLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRY 478
            CGG V  E      Y  ++   N YP   +C W I   E   V L F+ F++E    C Y
Sbjct: 867  CGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 926

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATS 658
            D +E+F G  ++  RLGR+CG+  P  + + G+ V ++  SD+    +GF L Y+     
Sbjct: 927  DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 986

Query: 659  GTEH 670
             T H
Sbjct: 987  DTLH 990



 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 42/122 (34%), Positives = 56/122 (45%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CG  L+ + G  ++P +P   Y   + C W I   P + I L F   DL     C YD V
Sbjct: 329  CGETLQDSTGNFSSPEYPNG-YSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYV 387

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGAT 1036
             V +G       R G+FCG K P PI S  + L V+F S  +    GF A Y  +  G  
Sbjct: 388  EVRDGFWRKAPLR-GRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDV 446

Query: 1037 EK 1042
            +K
Sbjct: 447  KK 448


>ref|XP_003356512.1| PREDICTED: CUB domain-containing protein 2-like [Sus scrofa].
          Length = 713

 Score =  160 bits (405), Expect = 2e-39
 Identities = 88/235 (37%), Positives = 119/235 (50%), Gaps = 1/235 (0%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG ++  SG  +S  FP LYP N EC W I V E  +V L+F  FDLE H +C +D LE
Sbjct: 203  CGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFLE 262

Query: 491  VFAG-SGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTE 667
            ++ G SG  G  LGRFCG   P P  +  + +++   SD+    RGF        ++G +
Sbjct: 263  IYNGASGDQGNLLGRFCGQVPPPPFTSSWHVMSVVFHSDKHVASRGF--------SAGYQ 314

Query: 668  HQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRY 847
               CGG L    G LT+P +P ++YP  + C W I A     + L F  F +E    C Y
Sbjct: 315  KDVCGGVLTGLSGVLTSPEYP-NNYPNNVECRWVIRAAGPATVKLVFADFQVEGSEQCTY 373

Query: 848  DSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
            D V+V  G           +CG   P  + S G+EL V F SD ++   GF A Y
Sbjct: 374  DYVAVLEGPGPAHGHH---YCGSARPSTLVSLGHELQVVFKSDFNIGGRGFKAYY 425



 Score =  145 bits (366), Expect = 6e-35
 Identities = 93/253 (36%), Positives = 131/253 (51%), Gaps = 5/253 (1%)
 Frame = +2

Query: 269  AQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVF 448
            ++G +  Y + V  CGG +TG SG L S  +PN YP N EC W I      TV L F  F
Sbjct: 306  SRGFSAGYQKDV--CGGVLTGLSGVLTSPEYPNNYPNNVECRWVIRAAGPATVKLVFADF 363

Query: 449  DLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGF 628
             +E    C YD + V  G G +      +CG+ RP+ LV+ G+++ +   SD   GGRGF
Sbjct: 364  QVEGSEQCTYDYVAVLEGPGPAHGH--HYCGSARPSTLVSLGHELQVVFKSDFNIGGRGF 421

Query: 629  LLWY-SGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLT 805
              +Y SG          C       +G  ++P +P S YP  I C W I  PP   + + 
Sbjct: 422  KAYYFSGE---------CQEVYTAVRGNFSSPQYP-SSYPNNIRCHWTIRLPPGYRVKVF 471

Query: 806  FGKFDLE-PDSY---CRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVS 973
            F   DLE P+S    C +D ++ F+GA S++A  LG +CG   P P++S  N+LL+   +
Sbjct: 472  FLDLDLEGPNSLTRTCDFDYLAAFDGA-SEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHT 530

Query: 974  DLSVTADGFSASY 1012
            D S T  GFS +Y
Sbjct: 531  DRSTTRRGFSVAY 543



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 45/113 (39%), Positives = 60/113 (53%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CGG L    G  ++PN+P   YP    CSW I+      + LTF  FDLE    C +D +
Sbjct: 203  CGGVLSAPSGNFSSPNFPRL-YPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFL 261

Query: 857  SVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYR 1015
             ++NGA  D    LG+FCG   P P +S  + + V F SD  V + GFSA Y+
Sbjct: 262  EIYNGASGDQGNLLGRFCGQVPPPPFTSSWHVMSVVFHSDKHVASRGFSAGYQ 314



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 40/116 (34%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLE----LHPSCRY 478
           C    T   G  +S  +P+ YP N  C WTI +P    V + F   DLE    L  +C +
Sbjct: 430 CQEVYTAVRGNFSSPQYPSSYPNNIRCHWTIRLPPGYRVKVFFLDLDLEGPNSLTRTCDF 489

Query: 479 DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSG 646
           D L  F G+      LG +CG   P P+ +  NQ+ L + +D  T  RGF + Y G
Sbjct: 490 DYLAAFDGASEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAYLG 545


>ref|XP_003130846.1| PREDICTED: neuropilin-1 [Sus scrofa].
          Length = 923

 Score =  150 bits (380), Expect = 1e-36
 Identities = 90/252 (35%), Positives = 133/252 (52%), Gaps = 9/252 (3%)
 Frame = +2

Query: 311  CGGDVTGES-GYLASEGFPNLYPPNKECIWTITVPES-QTVSLSFRV-FDLELHPSCRYD 481
            CG  +  ES GYL S G+P+ Y  +++C W I  PE  Q + ++F   FDLE    C+YD
Sbjct: 27   CGDTIKIESPGYLTSPGYPHSYHSSEKCEWLIQAPEPYQRIMINFNPHFDLE-DRDCKYD 85

Query: 482  ALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSG 661
             +EV  G   +G+  G+FCG   P+P+V+ G  + ++  SD  T G GF + Y      G
Sbjct: 86   YVEVIDGENENGRLWGKFCGKIAPSPVVSSGPFLFIKFVSDYETHGAGFSIRYE-IFKRG 144

Query: 662  TEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDS-- 835
             E   C        G + +P +PE  YP  + C++ I AP    I L F  FDLEPDS  
Sbjct: 145  PE---CSQNYTTPSGVIKSPGFPEK-YPNSLECTYIIFAPKMSEIILEFESFDLEPDSNP 200

Query: 836  ----YCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFS 1003
                +CRYD + +++G   D    +G++CG K PG + S    L + F +D ++  +GFS
Sbjct: 201  PGGMFCRYDRLEIWDG-FPDVGPHIGRYCGQKTPGRVRSSSGILSMVFYTDSAIAKEGFS 259

Query: 1004 ASYRTLPRGATE 1039
            A+Y  L    +E
Sbjct: 260  ANYSVLQSSVSE 271



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 50/172 (29%), Positives = 74/172 (43%), Gaps = 25/172 (14%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPS------C 472
           C  + T  SG + S GFP  YP + EC + I  P+   + L F  FDLE   +      C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIIFAPKMSEIILEFESFDLEPDSNPPGGMFC 206

Query: 473 RYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRA 652
           RYD LE++ G    G  +GR+CG   P  + +    +++   +D      GF   YS   
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRVRSSSGILSMVFYTDSAIAKEGFSANYSVLQ 266

Query: 653 TSGTEHQFC-------GGRLEKAQGTLT---TPNW---------PESDYPPG 751
           +S +E   C        G +   Q T +   + NW         PE+ + PG
Sbjct: 267 SSVSEDFKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLHYPENGWTPG 318


>ref|XP_003361777.1| PREDICTED: CUB domain-containing protein 2-like [Sus scrofa].
          Length = 486

 Score =  144 bits (364), Expect = 1e-34
 Identities = 88/240 (36%), Positives = 125/240 (52%), Gaps = 6/240 (2%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG ++  SG  +S  FP LYP N EC W I V E  +V L+F  FDLE H +C +D LE
Sbjct: 100  CGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFLE 159

Query: 491  VFAG-SGTSGQR-LGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGT 664
            ++ G SG  G   LGRFCG   P P  +  + +++ +    G        ++SG      
Sbjct: 160  IYNGASGDQGNXLLGRFCGQVPPPPFTSSWHVMSMCVVVSXGFKA----YYFSGE----- 210

Query: 665  EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLE-PDSY- 838
                C       +G  ++P +P S YP  I C W I  PP   + + F   DLE P+S  
Sbjct: 211  ----CQEVYTAVRGNFSSPQYP-SSYPNNIRCHWTIRLPPGYRVKVFFLDLDLEGPNSLT 265

Query: 839  --CRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
              C +D ++ F+GA S++A  LG +CG   P P++S  N+LL+   +D S T  GFS +Y
Sbjct: 266  RTCDFDYLAAFDGA-SEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAY 324



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 40/116 (34%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLE----LHPSCRY 478
           C    T   G  +S  +P+ YP N  C WTI +P    V + F   DLE    L  +C +
Sbjct: 211 CQEVYTAVRGNFSSPQYPSSYPNNIRCHWTIRLPPGYRVKVFFLDLDLEGPNSLTRTCDF 270

Query: 479 DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSG 646
           D L  F G+      LG +CG   P P+ +  NQ+ L + +D  T  RGF + Y G
Sbjct: 271 DYLAAFDGASEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAYLG 326


>ref|XP_003357786.1| PREDICTED: cubilin-like [Sus scrofa].
          Length = 2919

 Score =  141 bits (356), Expect = 9e-34
 Identities = 81/238 (34%), Positives = 120/238 (50%), Gaps = 3/238 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG+++G++G  +S G+P  YP NKECIW I      ++ L+   FD+E H +C +D LE
Sbjct: 711  CGGELSGDTGTFSSPGYPVGYPANKECIWYIHSSPGSSIQLTIHDFDVEYHATCNFDVLE 770

Query: 491  VFAGSGTSGQRLGRFC---GTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSG 661
            ++ G      R+ + C       P  + + GN++ LR  +D    GRGF +  S RA  G
Sbjct: 771  IYGGPDFHSPRIAQLCVQRSAENPMQVSSTGNELALRFKTDSSVNGRGFNV--SWRAVPG 828

Query: 662  TEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
                 CGG  +   G + +PN+P S Y     C+W I    +  + L F  FDLEP   C
Sbjct: 829  G----CGGIFQAPSGEIHSPNYP-SPYRSNTECTWLIQVEKNHRVLLNFTDFDLEPQDSC 883

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYR 1015
                +  F+G  S  A+ +G     +   PI S G+ L V+F S  S  + GF A +R
Sbjct: 884  ----IMAFDGLSSATARLVGVCGRQQLSNPIISTGSSLFVRFQSGPSRQSRGFRAQFR 937



 Score =  141 bits (356), Expect = 9e-34
 Identities = 106/309 (34%), Positives = 149/309 (48%), Gaps = 10/309 (3%)
 Frame = +2

Query: 149  STQLLPLS*GPQRLSPPTMLPAATASXXXXXXXXXXXXXFAQGQTPNYTRPVFLCGGDVT 328
            ST L+ L  G + LSP T+      +             F+   TP        CGG   
Sbjct: 2288 STPLVTLC-GDEALSPVTISGPVLLNFYSNAHTTDFGFKFSYRITP--------CGGTFN 2338

Query: 329  GESGYLASEGFP-NLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALEVFAGS 505
               G + S  +  + YP +  C++T+TV + + + L F  FDL     C  D LE++ GS
Sbjct: 2339 LSFGIIKSPSYSYSNYPNDMHCLYTVTVRDDRVIQLKFNDFDLVPSTFCSQDYLEIYDGS 2398

Query: 506  GTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEHQFCGG 685
              S   LG+FCG+  P  + +  N + L   +D     RG+ +  S R T G + Q CGG
Sbjct: 2399 NISDPLLGKFCGSTLPPNVKSSNNTMFLVFKTDSVHTARGWKI--SFRETLGPQ-QGCGG 2455

Query: 686  RLEKAQGTLTTPNWPESD----YPPGISCSWHIIAPPDQVISLTFGKFDLEPDS---YCR 844
             L    G+  T   P+SD    Y   ++C W I AP +++I LTF  F LE  +    C 
Sbjct: 2456 YL---TGSTHTFGSPDSDSNGRYDKNLNCIWFITAPVNKLIKLTFSTFALEAATSLQRCI 2512

Query: 845  YDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTL- 1021
            YD V +++G  S++A   G FCG   P P  S GN L VQFVSD S+  +GF+A+Y  L 
Sbjct: 2513 YDYVKLYDGD-SENANLAGTFCGSTVPAPFISSGNFLTVQFVSDSSLEREGFNATYTLLD 2571

Query: 1022 -PRGATEKA 1045
             P G T  A
Sbjct: 2572 MPCGGTYNA 2580



 Score =  135 bits (340), Expect = 6e-32
 Identities = 76/236 (32%), Positives = 113/236 (47%), Gaps = 2/236 (0%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGG   G+ G ++S  +P  Y     C W +  P+  T++L+F  FD+E H SC +D++ 
Sbjct: 1985 CGGIQIGDHGVISSPNYPASYDSLTHCSWLLEAPQGHTITLTFSDFDIEAHASCAWDSVT 2044

Query: 491  VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
            V  G       +G +CG+  P  + +  NQ+ +   +D      GF       AT  TE 
Sbjct: 2045 VRNGGSPGSPIIGHYCGSSNPRTIQSGSNQLVVIFNTDSSVQNGGFY------ATWNTET 2098

Query: 671  QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEP--DSYCR 844
              CGG L    GT+ +P+WP+ ++P    CSW +I  P + + ++F    L P  DS C 
Sbjct: 2099 SGCGGILHSDTGTIRSPHWPQ-NFPENSRCSWTVITHPSKHLEISFDNNFLIPSGDSQCL 2157

Query: 845  YDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
               V V+ G    D   L   CG+ +PG I +  N     F S     A GFSAS+
Sbjct: 2158 NSFVKVWAGTQEADKDLLATSCGNVSPGRIITPRNAFTAVFQSQ-ETPAQGFSASF 2212



 Score =  130 bits (327), Expect = 2e-30
 Identities = 78/246 (31%), Positives = 120/246 (48%), Gaps = 4/246 (1%)
 Frame = +2

Query: 299  PVFLCGG---DVTGESGYLASEGFPNL-YPPNKECIWTITVPESQTVSLSFRVFDLELHP 466
            P  +CGG   DV+G   Y++    P++ Y  + +C W +   E + + ++F  F LE   
Sbjct: 160  PQQVCGGTMSDVSGSFSYMS----PDVGYVHDVDCFWVLRTEEGKVLRITFTFFQLESVD 215

Query: 467  SCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSG 646
            +C ++ L++  G   +   LGRFCG+  P  L++  N +     S+     RGF + +  
Sbjct: 216  NCPHEFLQIHDGDSPAAFPLGRFCGSSPPHELLSSDNALYFHFFSEHLRNERGFTIRWE- 274

Query: 647  RATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLE 826
                 T    CGG L    G+L +P +P   YPPG  C W +IA PD +I+ TFG   LE
Sbjct: 275  -----TRQPECGGVLTGTYGSLKSPGYP-GKYPPGRDCVWKVIASPDLLITFTFGTLSLE 328

Query: 827  PDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSA 1006
                CR D + + +G +  D   LGKFC   +  P+ + G    + F SD  +   GF  
Sbjct: 329  HHDDCRKDYLEIRDGPLHQDPV-LGKFCTSLSVPPLQTTGPFARIHFHSDNQINDQGFHI 387

Query: 1007 SYRTLP 1024
            +Y T P
Sbjct: 388  TYLTTP 393



 Score =  130 bits (327), Expect = 2e-30
 Identities = 80/237 (33%), Positives = 118/237 (49%), Gaps = 3/237 (1%)
 Frame = +2

Query: 311  CGGDVTGES-GYLASEGFPNLYPPNKECIWTITV-PESQTVSLSFRVFDLELHPSCRYDA 484
            CGG +  +S   ++S  FP  YP N+ C W I   P    ++LSF  F LE   +C  D 
Sbjct: 940  CGGHILTDSFDTISSPRFPASYPNNQNCSWIIQAQPPFNHITLSFSHFGLESSSTCTRDF 999

Query: 485  LEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGT 664
            +E+  GS +     GR+CG+  P P+ + GN + LR  SD      GF       AT   
Sbjct: 1000 VEILDGSHSDAPLRGRYCGSSMPHPITSFGNALMLRFVSDSSVNFDGF------HATYVA 1053

Query: 665  EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCR 844
                CGG    A+G   +P +PE  YP  + C W+I + P   + L+F  F LE    C 
Sbjct: 1054 STSACGGIFHMAEGIFNSPGYPEV-YPSNVECVWNIASSPGNQLQLSFITFQLEDSRDCS 1112

Query: 845  YDSVSVFNGAVSDDAKRLGKFCGDKAPGPISS-EGNELLVQFVSDLSVTADGFSASY 1012
             D V +  G  +   + +G++CG+  P   SS  G++L ++FVSD S +  GF A++
Sbjct: 1113 RDFVEIREGNAT--GRLVGRYCGNVLPLNYSSIIGHDLWIKFVSDGSGSGVGFQAAF 1167



 Score =  128 bits (322), Expect = 8e-30
 Identities = 74/245 (30%), Positives = 116/245 (47%), Gaps = 5/245 (2%)
 Frame = +2

Query: 311  CGGDV----TGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFR-VFDLELHPSCR 475
            CGG++       SGY+AS   P+ YP + +CIW I  P  + + L F   F +E+ P+C 
Sbjct: 1513 CGGNIYIHDADSSGYVASPNHPDNYPQHADCIWVIAAPSGRPIRLEFEDQFSIEITPNCT 1572

Query: 476  YDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRAT 655
               LE+  G+ ++   L +FCGT  P   ++ G  + LR  SD      GF   YS    
Sbjct: 1573 SSYLELRDGADSNAPVLAKFCGTSLPPSQLSSGEVMYLRFRSDNSPTHAGFKAKYSIAQ- 1631

Query: 656  SGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDS 835
                   CGG +    G + +  +P   Y   + C W +       +++ F  F+L+  S
Sbjct: 1632 -------CGGTVTGQSGVIESSGYPALPYANNLFCEWRLQGLSGHYLTIHFEDFNLQNSS 1684

Query: 836  YCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYR 1015
             C  D V ++    S +   LG++CG+  P  I + GN  LV+FV+D  +TA GF   + 
Sbjct: 1685 GCERDFVEIWENHTSGNL--LGRYCGNTVPDSIDTSGNVALVRFVTDGFLTASGFRLRFD 1742

Query: 1016 TLPRG 1030
            +   G
Sbjct: 1743 SSMEG 1747



 Score =  125 bits (314), Expect = 6e-29
 Identities = 89/259 (34%), Positives = 125/259 (48%), Gaps = 7/259 (2%)
 Frame = +2

Query: 275  GQTPNYTRPV-FLCGGDVTGE-SGYLASEGFPNL--YPPNKECIWTITVPE--SQTVSLS 436
            G T +YT     +CGG +T    G   S G+     Y  N  C WT++     + ++ + 
Sbjct: 1853 GFTASYTSSEDAVCGGSLTNSPEGNFTSPGYDGTRNYSRNLNCEWTLSNSNQGNSSIYID 1912

Query: 437  FRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPA-PLVAPGNQVTLRMTSDEGT 613
            F  F LE H  C++D LE F      G  + R CG+ +P  PLV P  QV +   ++E  
Sbjct: 1913 FEDFYLESHQDCQFDVLE-FRVDNADGLLIWRLCGSSKPTMPLVIPYPQVWIHFVTNERV 1971

Query: 614  GGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQV 793
               GF   YS           CGG      G +++PN+P S Y     CSW + AP    
Sbjct: 1972 EHIGFRARYS--------FTDCGGIQIGDHGVISSPNYPAS-YDSLTHCSWLLEAPQGHT 2022

Query: 794  ISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVS 973
            I+LTF  FD+E  + C +DSV+V NG  S  +  +G +CG   P  I S  N+L+V F +
Sbjct: 2023 ITLTFSDFDIEAHASCAWDSVTVRNGG-SPGSPIIGHYCGSSNPRTIQSGSNQLVVIFNT 2081

Query: 974  DLSVTADGFSASYRTLPRG 1030
            D SV   GF A++ T   G
Sbjct: 2082 DSSVQNGGFYATWNTETSG 2100



 Score =  120 bits (302), Expect = 2e-27
 Identities = 78/236 (33%), Positives = 113/236 (47%), Gaps = 2/236 (0%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNL-YPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDAL 487
            CGG VTG+SG + S G+P L Y  N  C W +       +++ F  F+L+    C  D +
Sbjct: 1632 CGGTVTGQSGVIESSGYPALPYANNLFCEWRLQGLSGHYLTIHFEDFNLQNSSGCERDFV 1691

Query: 488  EVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTE 667
            E++    TSG  LGR+CG   P  +   GN   +R  +D      GFL     R    + 
Sbjct: 1692 EIWENH-TSGNLLGRYCGNTVPDSIDTSGNVALVRFVTD------GFLTASGFRLRFDSS 1744

Query: 668  HQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRY 847
             + CGG L+   GT T PN+   + P G  C W I     + ++LT     LE   +C  
Sbjct: 1745 MEGCGGDLQGPTGTFTAPNYLNPN-PHGWMCEWRITVQEGRRVTLTLNDLRLEAHPFCNS 1803

Query: 848  DSVSVFNGAVSDDAKRLGKFCGD-KAPGPISSEGNELLVQFVSDLSVTADGFSASY 1012
            + V+VFNG +  ++ +L K C        I S GN + V + +D S    GF+ASY
Sbjct: 1804 EHVAVFNG-IRSNSPQLEKRCSSVNGSNEIRSSGNTMKVVYFTDGSRPYGGFTASY 1858



 Score =  114 bits (284), Expect = 2e-25
 Identities = 68/228 (29%), Positives = 113/228 (49%), Gaps = 2/228 (0%)
 Frame = +2

Query: 290  YTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPS 469
            +T  +  C  +     G L S G+P  Y  + +C   +  P++ T+SL F  F LE    
Sbjct: 2684 FTYRIAGCSREYQKAFGRLRSPGWPAGYASDADCAVVLRAPQNHTISLFFHAFGLEDSGG 2743

Query: 470  CRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGF-LLWYSG 646
            C  D LEV  GS ++   LG++CGT  P P+ +    + LR  SD  T GRG+ ++W S 
Sbjct: 2744 CTRDFLEVRNGSESTSPLLGKYCGTLLPNPIFSQSRDLYLRFKSDSATSGRGYEIIWTS- 2802

Query: 647  RATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLE 826
             + SG     CGG L    G +T+P +P   YP    C W IIAP  + ++++F    ++
Sbjct: 2803 -SPSG-----CGGTLYGDSGLVTSPGYP-GTYPNHTHCEWVIIAPGGRPVTVSFSFISID 2855

Query: 827  PDSYCRYDSVSVFNGAVSDDAKRLGKFCG-DKAPGPISSEGNELLVQF 967
                C  + + +++G  ++     G +CG D    P ++  + + ++F
Sbjct: 2856 DPGECVQNYLMLYDGPDANSPSS-GPYCGADTDVAPFAASSHRVFIRF 2902



 Score =  112 bits (279), Expect = 7e-25
 Identities = 73/239 (30%), Positives = 108/239 (45%), Gaps = 4/239 (1%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLE----LHPSCRY 478
            CG + T  SGY+ S  +P  Y  N  C + I       + L    F LE    +  SC  
Sbjct: 2216 CGRNFTNPSGYIVSPNYPKQYDNNMNCTYIIEASPLSVILLKVVSFHLEARSTVSGSCDS 2275

Query: 479  DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATS 658
            D + +  G   S   L   CG    +P+   G  V L   S+  T   GF   +S R T 
Sbjct: 2276 DGVHIIRGHSLSSTPLVTLCGDEALSPVTISG-PVLLNFYSNAHTTDFGFK--FSYRITP 2332

Query: 659  GTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSY 838
                  CGG    + G + +P++  S+YP  + C + +    D+VI L F  FDL P ++
Sbjct: 2333 ------CGGTFNLSFGIIKSPSYSYSNYPNDMHCLYTVTVRDDRVIQLKFNDFDLVPSTF 2386

Query: 839  CRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYR 1015
            C  D + +++G+   D   LGKFCG   P  + S  N + + F +D   TA G+  S+R
Sbjct: 2387 CSQDYLEIYDGSNISD-PLLGKFCGSTLPPNVKSSNNTMFLVFKTDSVHTARGWKISFR 2444



 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 53/177 (29%), Positives = 75/177 (42%)
 Frame = +2

Query: 311 CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
           CGG +TG  G L S G+P  YPP ++C+W +       ++ +F    LE H  CR D LE
Sbjct: 280 CGGVLTGTYGSLKSPGYPGKYPPGRDCVWKVIASPDLLITFTFGTLSLEHHDDCRKDYLE 339

Query: 491 VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEH 670
           +  G       LG+FC +    PL   G    +   SD     +GF + Y    T    H
Sbjct: 340 IRDGPLHQDPVLGKFCTSLSVPPLQTTGPFARIHFHSDNQINDQGFHITY--LTTPSDLH 397

Query: 671 QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYC 841
             CGG     +G L+        +     C + I  P  + I + F   +LE  S C
Sbjct: 398 --CGGNFTDPEGLLSPD--LSGPFTHSRQCIYVITQPLGEQIQVNFTHVELEGQSGC 450



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 76/261 (29%), Positives = 107/261 (40%), Gaps = 8/261 (3%)
 Frame = +2

Query: 272  QGQTPNYTRPVFLCGGDV----TGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSF 439
            +G    YT     CGG      T +S +  S   P++  P   C W I  P  Q V ++ 
Sbjct: 2561 EGFNATYTLLDMPCGGTYNATWTSQSIWSPSSSDPDV--PLTTCTWVIEAPLHQQVEITV 2618

Query: 440  RVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPA-PLVAPGNQVTLRMTSDE--G 610
              F L     C  + LE       +G    RFCG    A P         + +   E   
Sbjct: 2619 WTFQLHSQ-DCDQNYLEFRDPPERNGNPGIRFCGRNASAVPTFYSSLSTAIIIFKSEVFN 2677

Query: 611  TGGR-GFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPD 787
            T  R GF    +G          C    +KA G L +P WP + Y     C+  + AP +
Sbjct: 2678 TDSRVGFTYRIAG----------CSREYQKAFGRLRSPGWP-AGYASDADCAVVLRAPQN 2726

Query: 788  QVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQF 967
              ISL F  F LE    C  D + V NG+ S  +  LGK+CG   P PI S+  +L ++F
Sbjct: 2727 HTISLFFHAFGLEDSGGCTRDFLEVRNGSEST-SPLLGKYCGTLLPNPIFSQSRDLYLRF 2785

Query: 968  VSDLSVTADGFSASYRTLPRG 1030
             SD + +  G+   + + P G
Sbjct: 2786 KSDSATSGRGYEIIWTSSPSG 2806



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 62/240 (25%), Positives = 107/240 (44%), Gaps = 6/240 (2%)
 Frame = +2

Query: 311  CGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALE 490
            CGGD+ G +G   +  + N  P    C W ITV E + V+L+     LE HP C  + + 
Sbjct: 1748 CGGDLQGPTGTFTAPNYLNPNPHGWMCEWRITVQEGRRVTLTLNDLRLEAHPFCNSEHVA 1807

Query: 491  VFAGSGTSGQRLGRFCGTFRPA-PLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTE 667
            VF G  ++  +L + C +   +  + + GN + +   +D      GF   Y     + +E
Sbjct: 1808 VFNGIRSNSPQLEKRCSSVNGSNEIRSSGNTMKVVYFTDGSRPYGGFTASY-----TSSE 1862

Query: 668  HQFCGGRLEKA-QGTLTTPNWPES-DYPPGISCSWHI--IAPPDQVISLTFGKFDLEPDS 835
               CGG L  + +G  T+P +  + +Y   ++C W +      +  I + F  F LE   
Sbjct: 1863 DAVCGGSLTNSPEGNFTSPGYDGTRNYSRNLNCEWTLSNSNQGNSSIYIDFEDFYLESHQ 1922

Query: 836  YCRYDSVSVFNGAVSDDAKRLGKFCGDKAPG-PISSEGNELLVQFVSDLSVTADGFSASY 1012
             C++D +       + D   + + CG   P  P+     ++ + FV++  V   GF A Y
Sbjct: 1923 DCQFDVLEF--RVDNADGLLIWRLCGSSKPTMPLVIPYPQVWIHFVTNERVEHIGFRARY 1980



 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 42/121 (34%), Positives = 65/121 (53%), Gaps = 3/121 (2%)
 Frame = +2

Query: 677  CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSV 856
            CGG L    GT ++P +P   YP    C W+I + P   I LT   FD+E  + C +D +
Sbjct: 711  CGGELSGDTGTFSSPGYPVG-YPANKECIWYIHSSPGSSIQLTIHDFDVEYHATCNFDVL 769

Query: 857  SVFNGAVSDDAKRLGKFCGDKA---PGPISSEGNELLVQFVSDLSVTADGFSASYRTLPR 1027
             ++ G     + R+ + C  ++   P  +SS GNEL ++F +D SV   GF+ S+R +P 
Sbjct: 770  EIYGGP-DFHSPRIAQLCVQRSAENPMQVSSTGNELALRFKTDSSVNGRGFNVSWRAVPG 828

Query: 1028 G 1030
            G
Sbjct: 829  G 829



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 38/114 (33%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
 Frame = +2

Query: 290  YTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPS 469
            Y      CGG      G   S G+P +YP N EC+W I       + LSF  F LE    
Sbjct: 1051 YVASTSACGGIFHMAEGIFNSPGYPEVYPSNVECVWNIASSPGNQLQLSFITFQLEDSRD 1110

Query: 470  CRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVA-PGNQVTLRMTSDEGTGGRGF 628
            C  D +E+  G+ T G+ +GR+CG   P    +  G+ + ++  SD    G GF
Sbjct: 1111 CSRDFVEIREGNAT-GRLVGRYCGNVLPLNYSSIIGHDLWIKFVSDGSGSGVGF 1163



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 43/125 (34%), Positives = 59/125 (47%), Gaps = 5/125 (4%)
 Frame = +2

Query: 677  CGGRL----EKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTF-GKFDLEPDSYC 841
            CGG +      + G + +PN P++ YP    C W I AP  + I L F  +F +E    C
Sbjct: 1513 CGGNIYIHDADSSGYVASPNHPDN-YPQHADCIWVIAAPSGRPIRLEFEDQFSIEITPNC 1571

Query: 842  RYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTL 1021
                + + +GA S+ A  L KFCG   P    S G  + ++F SD S T  GF A Y   
Sbjct: 1572 TSSYLELRDGADSN-APVLAKFCGTSLPPSQLSSGEVMYLRFRSDNSPTHAGFKAKYSIA 1630

Query: 1022 PRGAT 1036
              G T
Sbjct: 1631 QCGGT 1635


  Database: RefSeq49_SP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 11,343,932
  Number of sequences in database:  24,897
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 24897
Number of Hits to DB: 43,097,970
Number of extensions: 1492205
Number of successful extensions: 8840
Number of sequences better than 1.0e-05: 51
Number of HSP's gapped: 8538
Number of HSP's successfully gapped: 172
Length of query: 520
Length of database: 11,343,932
Length adjustment: 103
Effective length of query: 417
Effective length of database: 8,779,541
Effective search space: 3661068597
Effective search space used: 3661068597
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)

BLASTN 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-002572
         (1561 letters)

Database: Sscrofa_10.2.fasta 
           4582 sequences; 2,808,509,378 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Sscrofa_Chr03                                                         541   e-151

>Sscrofa_Chr03 
||          Length = 144787322

 Score =  541 bits (273), Expect = e-151
 Identities = 273/273 (100%)
 Strand = Plus / Plus

                                                                           
Query: 927     gccccatctcctccgaagggaacgagctcctcgtccaattcgtctcggacctcagcgtca 986
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7922308 gccccatctcctccgaagggaacgagctcctcgtccaattcgtctcggacctcagcgtca 7922367

                                                                           
Query: 987     cggccgacggcttctcggcctcctacaggaccctgccgcggggcgccaccgagaaagcgc 1046
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7922368 cggccgacggcttctcggcctcctacaggaccctgccgcggggcgccaccgagaaagcgc 7922427

                                                                           
Query: 1047    cagcccagagcccgggggaggacgcccggccaagtcccccgctcctcggcccaggcccca 1106
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7922428 cagcccagagcccgggggaggacgcccggccaagtcccccgctcctcggcccaggcccca 7922487

                                                                           
Query: 1107    agcccggagccgggcccaaagtcaagcctgaactcccacctgaggagaaaccgaaggccg 1166
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7922488 agcccggagccgggcccaaagtcaagcctgaactcccacctgaggagaaaccgaaggccg 7922547

                                                
Query: 1167    cgcccaaggcggaggcaactccggcgggctccg 1199
               |||||||||||||||||||||||||||||||||
Sbjct: 7922548 cgcccaaggcggaggcaactccggcgggctccg 7922580



 Score =  515 bits (260), Expect = e-143
 Identities = 260/260 (100%)
 Strand = Plus / Plus

                                                                           
Query: 406     ggtccctgagagccagactgtgtccctctccttccgagtctttgacctggagctgcaccc 465
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7920021 ggtccctgagagccagactgtgtccctctccttccgagtctttgacctggagctgcaccc 7920080

                                                                           
Query: 466     ctcctgccggtacgatgctctggaggtctttgccgggtctggaacctcgggtcagcggct 525
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7920081 ctcctgccggtacgatgctctggaggtctttgccgggtctggaacctcgggtcagcggct 7920140

                                                                           
Query: 526     cggacgcttctgcggaaccttccggccggcgcccttagtcgcccctggcaaccaggtgac 585
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7920141 cggacgcttctgcggaaccttccggccggcgcccttagtcgcccctggcaaccaggtgac 7920200

                                                                           
Query: 586     cctgaggatgacatcggacgagggcacgggaggacgaggcttcctgctctggtacagcgg 645
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7920201 cctgaggatgacatcggacgagggcacgggaggacgaggcttcctgctctggtacagcgg 7920260

                                   
Query: 646     gcgggccacctccggcactg 665
               ||||||||||||||||||||
Sbjct: 7920261 gcgggccacctccggcactg 7920280



 Score =  353 bits (178), Expect = 2e-94
 Identities = 192/199 (96%)
 Strand = Plus / Plus

                                                                           
Query: 99      aggctgcctcatctggcactgattatccctgccgctgccgctgccgctgctcaactcagc 158
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7918407 aggctgcctcatctggcactgattatccctgccgctgccgctgccgctgctcaactcagc 7918466

                                                                           
Query: 159     tgctgcctctgtcttgaggaccccagcgcctctnnnnnnngaccatgctgcctgctgcca 218
               |||||||||||||||||||||||||||||||||       ||||||||||||||||||||
Sbjct: 7918467 tgctgcctctgtcttgaggaccccagcgcctctcccccccgaccatgctgcctgctgcca 7918526

                                                                           
Query: 219     ccgcctccctcttggggcccctcctcactgcctgggctctgctgccttttgcccagggcc 278
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7918527 ccgcctccctcttggggcccctcctcactgcctgggctctgctgccttttgcccagggcc 7918586

                                  
Query: 279     agacccccaactacaccag 297
               |||||||||||||||||||
Sbjct: 7918587 agacccccaactacaccag 7918605



 Score =  343 bits (173), Expect = 2e-91
 Identities = 173/173 (100%)
 Strand = Plus / Plus

                                                                           
Query: 1277    gtggtgacggcaacagtgaagtccatggttcggggccctggggagggcctcacagtcacc 1336
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7923049 gtggtgacggcaacagtgaagtccatggttcggggccctggggagggcctcacagtcacc 7923108

                                                                           
Query: 1337    gtcagtctcattggtgtttacaaaaccggaggcctggacctgccctctccacccactgac 1396
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7923109 gtcagtctcattggtgtttacaaaaccggaggcctggacctgccctctccacccactgac 7923168

                                                                    
Query: 1397    acttccctgaagttttatgcaccctgcaagcagtgtccccccatgaagaaagg 1449
               |||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7923169 acttccctgaagttttatgcaccctgcaagcagtgtccccccatgaagaaagg 7923221



 Score =  280 bits (141), Expect = 2e-72
 Identities = 141/141 (100%)
 Strand = Plus / Plus

                                                                           
Query: 787     ccaggtgatctcactgaccttcgggaagtttgatctggagcccgactcctactgccgcta 846
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7921857 ccaggtgatctcactgaccttcgggaagtttgatctggagcccgactcctactgccgcta 7921916

                                                                           
Query: 847     cgactcggtcagcgtgttcaacggagccgtgagcgacgacgccaagcgactggggaagtt 906
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7921917 cgactcggtcagcgtgttcaacggagccgtgagcgacgacgccaagcgactggggaagtt 7921976

                                    
Query: 907     ctgcggcgacaaggccccagg 927
               |||||||||||||||||||||
Sbjct: 7921977 ctgcggcgacaaggccccagg 7921997



 Score =  254 bits (128), Expect = 1e-64
 Identities = 128/128 (100%)
 Strand = Plus / Plus

                                                                           
Query: 665     gagcaccaattttgcggggggcggctggagaaggcccagggaaccctgaccacgcccaac 724
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7921170 gagcaccaattttgcggggggcggctggagaaggcccagggaaccctgaccacgcccaac 7921229

                                                                           
Query: 725     tggcccgagtccgattaccccccgggcatcagctgttcctggcacatcatcgcgcccccg 784
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7921230 tggcccgagtccgattaccccccgggcatcagctgttcctggcacatcatcgcgcccccg 7921289

                       
Query: 785     gaccaggt 792
               ||||||||
Sbjct: 7921290 gaccaggt 7921297



 Score =  204 bits (103), Expect = 1e-49
 Identities = 109/111 (98%)
 Strand = Plus / Plus

                                                                           
Query: 1447    aggaaccagttatctgatgatgggccaggtggacgagaacagaggtcccatccttcctcc 1506
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7923363 aggaaccagttatctgatgatgggccaggtggacgagaacagaggtcccatccttcctcc 7923422

                                                                  
Query: 1507    agagagcttcgtggttctctaccggcccaaccagggacagatcctcaccaa 1557
               |||||||||||||||||||||||||||||||||||  ||||||||||||||
Sbjct: 7923423 agagagcttcgtggttctctaccggcccaaccaggaccagatcctcaccaa 7923473



 Score =  186 bits (94), Expect = 2e-44
 Identities = 108/115 (93%)
 Strand = Plus / Plus

                                                                           
Query: 294     ccagacctgtgttcctgtgtggaggggatgtgaccggggagtcgggttacctggcaagtg 353
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7919470 ccagacctgtgttcctgtgtggaggggatgtgaccggggagtcgggttacctggcaagtg 7919529

                                                                      
Query: 354     agggtttccctaacctctannnnnnnaataaggagtgcatctggacaataacggt 408
               |||||||||||||||||||       |||||||||||||||||||||||||||||
Sbjct: 7919530 agggtttccctaacctctacccccccaataaggagtgcatctggacaataacggt 7919584



 Score =  157 bits (79), Expect = 2e-35
 Identities = 79/79 (100%)
 Strand = Plus / Plus

                                                                           
Query: 1199    gatggacccagtgtcccctgcccaaagcagtgccgaaggacaggcacgttgcagagcaac 1258
               ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 7922840 gatggacccagtgtcccctgcccaaagcagtgccgaaggacaggcacgttgcagagcaac 7922899

                                  
Query: 1259    ttctgtaacagcaacctgg 1277
               |||||||||||||||||||
Sbjct: 7922900 ttctgtaacagcaacctgg 7922918



 Score = 75.8 bits (38), Expect = 6e-11
 Identities = 38/38 (100%)
 Strand = Plus / Plus

                                                     
Query: 1       gagaggcccctggactcgccactgtcccggctctacgc 38
               ||||||||||||||||||||||||||||||||||||||
Sbjct: 7918309 gagaggcccctggactcgccactgtcccggctctacgc 7918346


  Database: Sscrofa_10.2.fasta
    Posted date:  Nov 16, 2011 10:34 AM
  Number of letters in database: 2,808,509,378
  Number of sequences in database:  4582
  
Lambda     K      H
    1.37    0.711     1.31 

Gapped
Lambda     K      H
    1.37    0.711     1.31 


Matrix: blastn matrix:1 -3
Gap Penalties: Existence: 5, Extension: 2
Number of Sequences: 4582
Number of Hits to DB: 34,031,189
Number of extensions: 320
Number of successful extensions: 320
Number of sequences better than 1.0e-05: 1
Number of HSP's gapped: 319
Number of HSP's successfully gapped: 10
Length of query: 1561
Length of database: 2,808,509,378
Length adjustment: 21
Effective length of query: 1540
Effective length of database: 2,808,413,156
Effective search space: 4324956260240
Effective search space used: 4324956260240
X1: 11 (21.8 bits)
X2: 15 (29.7 bits)
X3: 50 (99.1 bits)
S1: 18 (36.2 bits)
S2: 30 (60.0 bits)