Search to RefSeqBP_Rel49
BLASTX 2.2.24 [Aug-08-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20110601C-006978
(1172 letters)
Database: RefSeq49_BP.fasta
33,088 sequences; 17,681,374 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_776954.1| cytochrome P450 2D14 [Bos taurus]. 382 e-124
Alignment gi|NP_001073833.1| hypothetical protein LOC785824 [Bos taurus]. 384 e-107
Alignment gi|XP_002686394.1| PREDICTED: cytochrome P450, family 2, subfam... 143 7e-39
Alignment gi|XP_609410.3| PREDICTED: cytochrome P450, family 2, subfamily... 143 7e-39
Alignment gi|XP_002707855.1| PREDICTED: cytochrome P450, family 2, subfam... 143 2e-38
Alignment gi|XP_587546.3| PREDICTED: cytochrome P450, family 2, subfamily... 143 2e-38
Alignment gi|XP_002686393.1| PREDICTED: similar to cytochrome P450 isofor... 137 2e-36
Alignment gi|NP_001033640.1| cytochrome P450, family 2, subfamily J, poly... 129 3e-35
Alignment gi|XP_589364.4| PREDICTED: similar to cytochrome P450 isoform 2... 129 3e-34
Alignment gi|NP_001069519.1| cytochrome P450, family 2, subfamily C, poly... 124 3e-32
>ref|NP_776954.1| cytochrome P450 2D14 [Bos taurus].
Length = 500
Score = 382 bits (981), Expect(2) = e-124
Identities = 192/275 (69%), Positives = 218/275 (79%)
Frame = +1
Query: 124 AMVIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSL 303
A++IFLLL+DLMHRRSRWAPRY QV+F+DPR SF QLRRRFG+VFSL
Sbjct: 15 ALLIFLLLLDLMHRRSRWAPRYPPGPTPLPVLGNLLQVDFEDPRPSFNQLRRRFGNVFSL 74
Query: 304 QQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQ 483
QQ+W PVVVLNGLAAVREALV S +T+DRPP + EHLGYGPR+EGVILARYG AW EQ
Sbjct: 75 QQVWTPVVVLNGLAAVREALVYRSQDTADRPPPAVYEHLGYGPRAEGVILARYGDAWAEQ 134
Query: 484 RRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTF 663
RRFS++TLRNFGLGKKSLE+WVT+EASC CAAFADQAGRPFSP +LLNKAVSNVIASLTF
Sbjct: 135 RRFSLTTLRNFGLGKKSLEQWVTEEASCSCAAFADQAGRPFSPMDLLNKAVSNVIASLTF 194
Query: 664 ARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMI 843
RFEYNDPR+ +R+V+EA+PVL IPGL A++FP QKAF+ +I
Sbjct: 195 GCRFEYNDPRIIKLLDLTEDGLKEEPNLVRKVVEAVPVLLSIPGLAARVFPAQKAFMALI 254
Query: 844 DELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
DELI E KMTRD QPPR LTDAFLDE+KEAKG P
Sbjct: 255 DELIAEQKMTRDPTQPPRHLTDAFLDEVKEAKGNP 289
Score = 82.4 bits (202), Expect(2) = e-124
Identities = 49/77 (63%), Positives = 52/77 (67%), Gaps = 2/77 (2%)
Frame = +3
Query: 948 PESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQE--NQ*GDRARA 1121
PESSFNDENLRLVVADLFSAGM+ MILHPDVQRRVQQE G R
Sbjct: 289 PESSFNDENLRLVVADLFSAGMVTTSTTLAWALLLMILHPDVQRRVQQEIDEVIGQVRRP 348
Query: 1122 ATGKKDQALMPFTLAVL 1172
G DQALMPFT+AV+
Sbjct: 349 EMG--DQALMPFTVAVV 363
>ref|NP_001073833.1| hypothetical protein LOC785824 [Bos taurus].
Length = 500
Score = 384 bits (987), Expect = e-107
Identities = 208/339 (61%), Positives = 239/339 (70%), Gaps = 3/339 (0%)
Frame = +1
Query: 124 AMVIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSL 303
A++IFLLL+DLMHRRSRWAPRY QV+F+DPR SF QLRRRFG+VFSL
Sbjct: 15 ALLIFLLLLDLMHRRSRWAPRYPPGPMPLPVLGNLLQVDFEDPRPSFNQLRRRFGNVFSL 74
Query: 304 QQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQ 483
QQ+W PVVVLNGLAAVREALV S +T+DRPP + +HLG+GPR+EGVILARYG AWREQ
Sbjct: 75 QQVWTPVVVLNGLAAVREALVYRSQDTADRPPQALYKHLGFGPRAEGVILARYGNAWREQ 134
Query: 484 RRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTF 663
RRFS+STLRNFGLGKKSLE+WVT+EASCLCAAFADQAG PFSP +LLNKAVSNVIASLTF
Sbjct: 135 RRFSLSTLRNFGLGKKSLEQWVTEEASCLCAAFADQAGHPFSPMDLLNKAVSNVIASLTF 194
Query: 664 ARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMI 843
RFEYNDPR+ MRQV+EA+PVL IPGL AK+ P QKAF+ ++
Sbjct: 195 GCRFEYNDPRIVKLLDVMEDGLKEEMKIMRQVVEAVPVLLSIPGLAAKVVPGQKAFMTLV 254
Query: 844 DELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKPPRAASMMRTSAWWWLTCSPLG*SPP 1023
DELI E KMTRD QPPR LTDAFLDE+KEAKG P + S L + L +
Sbjct: 255 DELIAEQKMTRDPTQPPRHLTDAFLDEVKEAKGNPESSFSDENLR----LVVADLFSAGM 310
Query: 1024 RPRWPGLXXXXXXXXXXXDASNR---KINEVIGHVRQPE 1131
L D R +I+EVIG VR+PE
Sbjct: 311 VTTSTTLAWALLLMILHPDVQRRVQQEIDEVIGQVRRPE 349
Score = 80.5 bits (197), Expect = 3e-15
Identities = 48/77 (62%), Positives = 52/77 (67%), Gaps = 2/77 (2%)
Frame = +3
Query: 948 PESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQE--NQ*GDRARA 1121
PESSF+DENLRLVVADLFSAGM+ MILHPDVQRRVQQE G R
Sbjct: 289 PESSFSDENLRLVVADLFSAGMVTTSTTLAWALLLMILHPDVQRRVQQEIDEVIGQVRRP 348
Query: 1122 ATGKKDQALMPFTLAVL 1172
G DQALMPFT+AV+
Sbjct: 349 EMG--DQALMPFTVAVV 363
>ref|XP_002686394.1| PREDICTED: cytochrome P450, family 2, subfamily J-like [Bos
taurus].
Length = 502
Score = 143 bits (360), Expect(2) = 7e-39
Identities = 89/272 (32%), Positives = 142/272 (52%), Gaps = 1/272 (0%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQ 309
++FLLL DL++RR Y Q++F+ LS + +++G++FSL+
Sbjct: 26 IVFLLLTDLLNRRR--PKNYPPGPPRLPFVGNFFQLDFEQGHLSLQRFVKKYGNLFSLEF 83
Query: 310 IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRR 489
P VV+ GL ++E LV +RP I E + + G+I++ G W+EQRR
Sbjct: 84 GDLPSVVITGLPLIKEVLVYQDQNFVNRPISPIRERVF---KKNGLIMSN-GHIWKEQRR 139
Query: 490 FSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFAR 669
FS++ LRNFGLG+KSLEE + +E + L A ++ G+PF+P+ +N AVSN+I S+TF
Sbjct: 140 FSLTALRNFGLGRKSLEERIQEEVAYLIQAIGEEKGQPFNPHFKINNAVSNIICSITFGE 199
Query: 670 RFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGLCAKLFPRQKAFLVMID 846
RF+Y D + Q+ P ++ +PG LF + + +
Sbjct: 200 RFDYQDDQFQELLRLLDEVTYLETTVWCQLYNVFPRIMNFLPGPHQMLFSNWRKLKMFVA 259
Query: 847 ELITEHKMTRDLAQPPRDLTDAFLDEMKEAKG 942
+I HK + A+ RD DA+L E ++ KG
Sbjct: 260 RVIENHKRDWNPAE-ARDFIDAYLQETEKHKG 290
Score = 37.0 bits (84), Expect(2) = 7e-39
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Frame = +3
Query: 954 SSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQE--NQ*GDRARAAT 1127
SSF++ENL DLF AG M L+P++Q +VQ E G+ + +T
Sbjct: 294 SSFHEENLIYNTLDLFFAGTETTSTTLRWGLLYMALYPEIQEKVQAEIDKVLGESQQPST 353
Query: 1128 GKKDQALMPFTLAVL 1172
++ MP+T AV+
Sbjct: 354 AARES--MPYTNAVI 366
>ref|XP_609410.3| PREDICTED: cytochrome P450, family 2, subfamily J-like [Bos
taurus].
Length = 502
Score = 143 bits (360), Expect(2) = 7e-39
Identities = 89/272 (32%), Positives = 142/272 (52%), Gaps = 1/272 (0%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQ 309
++FLLL DL++RR Y Q++F+ LS + +++G++FSL+
Sbjct: 26 IVFLLLTDLLNRRR--PKNYPPGPPRLPFVGNFFQLDFEQGHLSLQRFVKKYGNLFSLEF 83
Query: 310 IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRR 489
P VV+ GL ++E LV +RP I E + + G+I++ G W+EQRR
Sbjct: 84 GDLPSVVITGLPLIKEVLVYQDQNFVNRPISPIRERVF---KKNGLIMSN-GHIWKEQRR 139
Query: 490 FSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFAR 669
FS++ LRNFGLG+KSLEE + +E + L A ++ G+PF+P+ +N AVSN+I S+TF
Sbjct: 140 FSLTALRNFGLGRKSLEERIQEEVAYLIQAIGEEKGQPFNPHFKINNAVSNIICSITFGE 199
Query: 670 RFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGLCAKLFPRQKAFLVMID 846
RF+Y D + Q+ P ++ +PG LF + + +
Sbjct: 200 RFDYQDDQFQELLRLLDEVTYLETTVWCQLYNVFPRIMNFLPGPHQMLFSNWRKLKMFVA 259
Query: 847 ELITEHKMTRDLAQPPRDLTDAFLDEMKEAKG 942
+I HK + A+ RD DA+L E ++ KG
Sbjct: 260 RVIENHKRDWNPAE-ARDFIDAYLQETEKHKG 290
Score = 37.0 bits (84), Expect(2) = 7e-39
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Frame = +3
Query: 954 SSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQE--NQ*GDRARAAT 1127
SSF++ENL DLF AG M L+P++Q +VQ E G+ + +T
Sbjct: 294 SSFHEENLIYNTLDLFFAGTETTSTTLRWGLLYMALYPEIQEKVQAEIDKVLGESQQPST 353
Query: 1128 GKKDQALMPFTLAVL 1172
++ MP+T AV+
Sbjct: 354 AARES--MPYTNAVI 366
>ref|XP_002707855.1| PREDICTED: cytochrome P450, family 2, subfamily J, polypeptide
2-like [Bos taurus].
Length = 502
Score = 143 bits (360), Expect(2) = 2e-38
Identities = 91/270 (33%), Positives = 141/270 (52%), Gaps = 1/270 (0%)
Frame = +1
Query: 136 FLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQIW 315
FLL VD + RR Y Q++ + L Q +++G+VFSL
Sbjct: 28 FLLFVDFLKRRH--PKNYPPGPPGLPFVGNLFQLDPEKVPLVLHQFVKKYGNVFSLDFGT 85
Query: 316 RPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRRFS 495
P V++ GL ++E LV S+RP V + EH+ ++G+I++ G+ W+EQRRF+
Sbjct: 86 VPSVLITGLPLIKEVLVHQGQIFSNRPIVPLQEHI---INNKGLIMSS-GQLWKEQRRFA 141
Query: 496 VSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFARRF 675
++TLRNFGLGKKSLEE + +EAS L ++ G+PF P+ +N AVSN+I S+TF RF
Sbjct: 142 LTTLRNFGLGKKSLEERIQEEASYLIQTIREENGQPFDPHLTINNAVSNIICSITFGERF 201
Query: 676 EYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGLCAKLFPRQKAFLVMIDEL 852
+Y D + Q+ P ++ +PG LF + + + +
Sbjct: 202 DYQDDQFQELLRMLDEILNLQTSMCCQLYNVFPRIMNFLPGPHQALFSNMEKMKMFVARM 261
Query: 853 ITEHKMTRDLAQPPRDLTDAFLDEMKEAKG 942
I HK + A+ RD DA+L E+++ KG
Sbjct: 262 IENHKRDWNPAE-ARDFIDAYLQEIEKHKG 290
Score = 35.0 bits (79), Expect(2) = 2e-38
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*G 1106
E+ +G+ SSF +ENL DLF AG M L+P++Q +VQ E
Sbjct: 286 EKHKGDAT-SSFQEENLIYNTLDLFLAGTETTSTSLRWGLLFMALNPEIQEKVQAEI--- 341
Query: 1107 DRARAATGKKDQAL---MPFTLAVL 1172
DR + + A MP+T AV+
Sbjct: 342 DRVLGQSQQPSMAARESMPYTNAVI 366
>ref|XP_587546.3| PREDICTED: cytochrome P450, family 2, subfamily J, polypeptide
2-like [Bos taurus].
Length = 502
Score = 143 bits (360), Expect(2) = 2e-38
Identities = 91/270 (33%), Positives = 141/270 (52%), Gaps = 1/270 (0%)
Frame = +1
Query: 136 FLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQIW 315
FLL VD + RR Y Q++ + L Q +++G+VFSL
Sbjct: 28 FLLFVDFLKRRH--PKNYPPGPPGLPFVGNLFQLDPEKVPLVLHQFVKKYGNVFSLDFGT 85
Query: 316 RPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRRFS 495
P V++ GL ++E LV S+RP V + EH+ ++G+I++ G+ W+EQRRF+
Sbjct: 86 VPSVLITGLPLIKEVLVHQGQIFSNRPIVPLQEHI---INNKGLIMSS-GQLWKEQRRFA 141
Query: 496 VSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFARRF 675
++TLRNFGLGKKSLEE + +EAS L ++ G+PF P+ +N AVSN+I S+TF RF
Sbjct: 142 LTTLRNFGLGKKSLEERIQEEASYLIQTIREENGQPFDPHLTINNAVSNIICSITFGERF 201
Query: 676 EYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGLCAKLFPRQKAFLVMIDEL 852
+Y D + Q+ P ++ +PG LF + + + +
Sbjct: 202 DYQDDQFQELLRMLDEILNLQTSMCCQLYNVFPRIMNFLPGPHQALFSNMEKMKMFVARM 261
Query: 853 ITEHKMTRDLAQPPRDLTDAFLDEMKEAKG 942
I HK + A+ RD DA+L E+++ KG
Sbjct: 262 IENHKRDWNPAE-ARDFIDAYLQEIEKHKG 290
Score = 35.0 bits (79), Expect(2) = 2e-38
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*G 1106
E+ +G+ SSF +ENL DLF AG M L+P++Q +VQ E
Sbjct: 286 EKHKGDAT-SSFQEENLIYNTLDLFLAGTETTSTSLRWGLLFMALNPEIQEKVQAEI--- 341
Query: 1107 DRARAATGKKDQAL---MPFTLAVL 1172
DR + + A MP+T AV+
Sbjct: 342 DRVLGQSQQPSMAARESMPYTNAVI 366
>ref|XP_002686393.1| PREDICTED: similar to cytochrome P450 isoform 2J [Bos taurus].
Length = 502
Score = 137 bits (344), Expect(2) = 2e-36
Identities = 89/273 (32%), Positives = 145/273 (53%), Gaps = 2/273 (0%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQ- 306
V+FL L D + RR Y Q++F LS + +++G+VFS+
Sbjct: 26 VVFLFLDDFLKRRR--PKNYPPGPPPLPFVGNFFQLDFDKAHLSLQRFVKKYGNVFSVDF 83
Query: 307 QIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQR 486
I+R V++ GL ++EALV ++RP + I + + ++G+I++ G W+EQR
Sbjct: 84 GIFRSVLI-TGLPLIKEALVHQDQNFANRPLIPIEKRIF---NNKGLIMSN-GHVWKEQR 138
Query: 487 RFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFA 666
RF+++TLRNFGLGKKSLEE + +EA+ L ++ G+PF P+ +N AVSN+I S+TF
Sbjct: 139 RFALTTLRNFGLGKKSLEERIQEEAAYLIQEIGEENGQPFDPHFTINNAVSNIICSITFG 198
Query: 667 RRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGLCAKLFPRQKAFLVMI 843
RF+Y D + Q+ P ++ +PG LF + + + I
Sbjct: 199 ERFDYQDDQFQELLRLFDEMMHLRTSTCCQLYNIFPRIMSFLPGPQHALFSKWEKLKMFI 258
Query: 844 DELITEHKMTRDLAQPPRDLTDAFLDEMKEAKG 942
++ HK + A+ RD DA+L E+++ KG
Sbjct: 259 AGVVENHKRDWNPAE-ARDFIDAYLQEIEKHKG 290
Score = 35.0 bits (79), Expect(2) = 2e-36
Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 3/76 (3%)
Frame = +3
Query: 954 SSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARAATGK 1133
S F++ENL DLF AG M L+P++Q +VQ E DR + K
Sbjct: 294 SCFHEENLIYNTLDLFFAGTETTSTTLQWGLLYMALYPEIQEKVQAEI---DRVLGQSQK 350
Query: 1134 KDQAL---MPFTLAVL 1172
A MP+T AV+
Sbjct: 351 PSMAARESMPYTNAVI 366
>ref|NP_001033640.1| cytochrome P450, family 2, subfamily J, polypeptide 2 [Bos taurus].
Length = 502
Score = 129 bits (323), Expect(2) = 3e-35
Identities = 72/226 (31%), Positives = 128/226 (56%), Gaps = 1/226 (0%)
Frame = +1
Query: 268 QLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGV 447
Q+ +++G++ L +V+ GL ++EALV+ +RP + + +H+ ++G+
Sbjct: 70 QVVKKYGNIIRLNFGVIHFIVITGLPYIKEALVNQEQNFVNRPMIPLQKHIF---NNKGL 126
Query: 448 ILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLN 627
+ + G+ W+EQRRF+++TLRNFGLG+KSLEE + +E + L A ++ G+PF P+ ++N
Sbjct: 127 VRSN-GQVWKEQRRFTLTTLRNFGLGRKSLEERIQEEVTYLIQAIGEENGQPFDPHFIIN 185
Query: 628 KAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGLCA 804
AVSN+I S+TF RF+Y D + Q+ A P ++ +PG
Sbjct: 186 NAVSNIICSITFGERFDYKDDQFQELLRLLDEILCIQASVCCQLYNAFPRIMNFLPGSHH 245
Query: 805 KLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAKG 942
LF + + + + +I H+ + A+ RD DA+L E+++ KG
Sbjct: 246 TLFRKWEKLKMFVANVIENHRKDWNPAE-ARDFIDAYLQEIEKHKG 290
Score = 38.9 bits (89), Expect(2) = 3e-35
Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
Frame = +3
Query: 954 SSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQE--NQ*GDRARAAT 1127
SSF+DENL DLF AG M L+P++Q +VQ E G + +T
Sbjct: 294 SSFDDENLICSTLDLFLAGTETTSTTLRWGLLFMALNPEIQEKVQAEIDRVLGQSQKVST 353
Query: 1128 GKKDQALMPFTLAVL 1172
++ MP+T AV+
Sbjct: 354 ASRES--MPYTNAVI 366
>ref|XP_589364.4| PREDICTED: similar to cytochrome P450 isoform 2J isoform 1, partial
[Bos taurus].
Length = 447
Score = 129 bits (324), Expect(2) = 3e-34
Identities = 79/230 (34%), Positives = 130/230 (56%), Gaps = 2/230 (0%)
Frame = +1
Query: 259 SFIQLRRRFGDVFSLQ-QIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPR 435
S Q +++G+VFS+ I+R V++ GL ++EALV ++RP + I + +
Sbjct: 12 SIFQFVKKYGNVFSVDFGIFRSVLI-TGLPLIKEALVHQDQNFANRPLIPIEKRIF---N 67
Query: 436 SEGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPN 615
++G+I++ G W+EQRRF+++TLRNFGLGKKSLEE + +EA+ L ++ G+PF P+
Sbjct: 68 NKGLIMSN-GHVWKEQRRFALTTLRNFGLGKKSLEERIQEEAAYLIQEIGEENGQPFDPH 126
Query: 616 NLLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIP 792
+N AVSN+I S+TF RF+Y D + Q+ P ++ +P
Sbjct: 127 FTINNAVSNIICSITFGERFDYQDDQFQELLRLFDEMMHLRTSTCCQLYNIFPRIMSFLP 186
Query: 793 GLCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAKG 942
G LF + + + I ++ HK + A+ RD DA+L E+++ KG
Sbjct: 187 GPQHALFSKWEKLKMFIAGVVENHKRDWNPAE-ARDFIDAYLQEIEKHKG 235
Score = 35.0 bits (79), Expect(2) = 3e-34
Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 3/76 (3%)
Frame = +3
Query: 954 SSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARAATGK 1133
S F++ENL DLF AG M L+P++Q +VQ E DR + K
Sbjct: 239 SCFHEENLIYNTLDLFFAGTETTSTTLRWGLLYMALYPEIQEKVQAEI---DRVLGQSQK 295
Query: 1134 KDQAL---MPFTLAVL 1172
A MP+T AV+
Sbjct: 296 PSMAARESMPYTNAVI 311
>ref|NP_001069519.1| cytochrome P450, family 2, subfamily C, polypeptide 18 [Bos
taurus].
Length = 490
Score = 124 bits (312), Expect(2) = 3e-32
Identities = 82/237 (34%), Positives = 117/237 (49%), Gaps = 1/237 (0%)
Frame = +1
Query: 232 QVNFQDPRLSFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFIL 411
Q++ ++ S L +G VF++ RP VVL+G AV+EAL+ E S R + +
Sbjct: 44 QLDVKNIGKSLSNLSNTYGPVFTVYFGLRPTVVLHGYEAVKEALIDQGEEFSGRGNIPMS 103
Query: 412 EHLGYGPRSEGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQ 591
+ + G G+I + GK W+E RRFS+ TLRNFG+GK+S+E+ V +EA CL
Sbjct: 104 QRVNKG---YGIIFSN-GKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEAHCLVEELRKT 159
Query: 592 AGRPFSPNNLLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAM 771
G P P +L A NVI S+ F RF+Y D QV
Sbjct: 160 NGSPCDPTFILGCAPCNVICSIIFQNRFDYTDQNFLNLLDKFNENLQVASSPWMQVCNTF 219
Query: 772 PVL-RHIPGLCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAK 939
P+L + PG KLF + E + EH+ T D+ PRD D FL +M++ K
Sbjct: 220 PILIDYFPGSHNKLFKNFAYIRSYVLEKVKEHQATLDI-NNPRDFIDCFLIKMEQEK 275
Score = 33.1 bits (74), Expect(2) = 3e-32
Identities = 22/74 (29%), Positives = 34/74 (45%)
Frame = +3
Query: 951 ESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARAATG 1130
E F ENL V+DLF AG ++ HP+V +VQ+E +
Sbjct: 279 EMEFTFENLIASVSDLFGAGTETTSTTLRYGLLMLLKHPEVTAKVQEEIDRVIGRHRSPC 338
Query: 1131 KKDQALMPFTLAVL 1172
+D++ MP+ AV+
Sbjct: 339 MQDRSHMPYMDAVV 352
Database: RefSeq49_BP.fasta
Posted date: Oct 17, 2011 1:42 PM
Number of letters in database: 17,681,374
Number of sequences in database: 33,088
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33088
Number of Hits to DB: 42,596,531
Number of extensions: 1120331
Number of successful extensions: 4046
Number of sequences better than 1.0e-05: 52
Number of HSP's gapped: 3967
Number of HSP's successfully gapped: 80
Length of query: 390
Length of database: 17,681,374
Length adjustment: 104
Effective length of query: 286
Effective length of database: 14,240,222
Effective search space: 4072703492
Effective search space used: 4072703492
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)
Search to RefSeqCP_Rel49
BLASTX 2.2.24 [Aug-08-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20110601C-006978
(1172 letters)
Database: RefSeq49_CP.fasta
33,336 sequences; 18,874,504 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_001003333.1| cytochrome P450 2D15 [Canis lupus familiaris]. 337 e-105
Alignment gi|XP_852725.1| PREDICTED: similar to cytochrome P450, family 2... 142 3e-37
Alignment gi|XP_541605.2| PREDICTED: similar to cytochrome P450, family 2... 117 9e-32
Alignment gi|NP_001183973.1| cytochrome P450 2C21 [Canis lupus familiaris]. 111 1e-29
Alignment gi|XP_533661.2| PREDICTED: similar to cytochrome P450 monooxyge... 127 2e-29
Alignment gi|XP_852606.1| PREDICTED: similar to cytochrome P450, family 2... 114 3e-29
Alignment gi|XP_855301.1| PREDICTED: similar to cytochrome P450, family 2... 123 3e-28
Alignment gi|NP_001003334.1| cytochrome P450 2C41 [Canis lupus familiaris]. 106 6e-28
Alignment gi|NP_001006653.1| cytochrome P450 2B11 [Canis lupus familiaris]. 120 2e-27
Alignment gi|XP_855605.1| PREDICTED: cytochrome P450 2B11 [Canis familiar... 120 2e-27
>ref|NP_001003333.1| cytochrome P450 2D15 [Canis lupus familiaris].
Length = 500
Score = 337 bits (865), Expect(2) = e-105
Identities = 166/275 (60%), Positives = 204/275 (74%)
Frame = +1
Query: 124 AMVIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSL 303
A+ IFLLLVDLMHRR RWA RY Q++FQ+P F QL+ RFG+VFSL
Sbjct: 15 AVAIFLLLVDLMHRRRRWATRYPPGPTPVPMVGNLLQMDFQEPICYFSQLQGRFGNVFSL 74
Query: 304 QQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQ 483
+ W PVVVLNGL AVREALV S +T+DRPP+ I +HLG GP S+G+ LARYG+AWREQ
Sbjct: 75 ELAWTPVVVLNGLEAVREALVHRSEDTADRPPMPIYDHLGLGPESQGLFLARYGRAWREQ 134
Query: 484 RRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTF 663
RRFS+STLRNFGLG+KSLE+WVT+EASCLCAAFA+QAGRPF P LLNKAVSNVI+SLT+
Sbjct: 135 RRFSLSTLRNFGLGRKSLEQWVTEEASCLCAAFAEQAGRPFGPGALLNKAVSNVISSLTY 194
Query: 664 ARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMI 843
RRFEY+DPR+ +R+ L ++PVL HIPGL +K+F QKA + +
Sbjct: 195 GRRFEYDDPRLLQLLELTQQALKQDSGFLREALNSIPVLLHIPGLASKVFSAQKAIITLT 254
Query: 844 DELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
+E+I EH+ TRD QPPR L DAF+DE+++AKG P
Sbjct: 255 NEMIQEHRKTRDPTQPPRHLIDAFVDEIEKAKGNP 289
Score = 65.9 bits (159), Expect(2) = e-105
Identities = 38/82 (46%), Positives = 48/82 (58%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*G 1106
E+ +G P++SFN+ENL +V +DLF AGM+ MILHPDVQRRVQQE
Sbjct: 283 EKAKGN-PKTSFNEENLCMVTSDLFIAGMVSTSITLTWALLLMILHPDVQRRVQQEIDEV 341
Query: 1107 DRARAATGKKDQALMPFTLAVL 1172
DQ MPFT+AV+
Sbjct: 342 IGREQLPEMGDQTRMPFTVAVI 363
>ref|XP_852725.1| PREDICTED: similar to cytochrome P450, family 2, subfamily J,
polypeptide 2 [Canis familiaris].
Length = 502
Score = 142 bits (358), Expect(2) = 3e-37
Identities = 87/272 (31%), Positives = 144/272 (52%), Gaps = 1/272 (0%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQ 309
V FL D + RR Y ++F+ L + +++G+VFS+Q
Sbjct: 26 VAFLFFADFLKRRR--PKNYPPGPVPLPFVGNFFHLDFEQSHLKLQRFVKKYGNVFSVQM 83
Query: 310 IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRR 489
P+VV+ GL ++E LV + +RP I E + ++ G+I++ G+ W+EQRR
Sbjct: 84 GDMPLVVVTGLPLIKEVLVDQNQVFVNRPITPIRERVF---KNSGLIMSS-GQIWKEQRR 139
Query: 490 FSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFAR 669
F+++TL+NFGLG+KS+EE + +EA L A ++ G+PF+P+ +N AVSN+I S+TF +
Sbjct: 140 FTLATLKNFGLGRKSIEERIQEEAHHLIQAIEEENGQPFNPHFKINNAVSNIICSITFGK 199
Query: 670 RFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGLCAKLFPRQKAFLVMID 846
RFEY D + Q+ P +++ +PG KLF + + I
Sbjct: 200 RFEYQDEQFQELLRLLDEVTCLETSMRCQLYNVFPWIIKFLPGPHQKLFNDWEKLKLFIA 259
Query: 847 ELITEHKMTRDLAQPPRDLTDAFLDEMKEAKG 942
+ H+ + A+ PRD DA+L EM++ +G
Sbjct: 260 HMTENHRRDWNPAE-PRDFIDAYLKEMEKNRG 290
Score = 32.3 bits (72), Expect(2) = 3e-37
Identities = 19/56 (33%), Positives = 28/56 (50%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQE 1094
E+ +G SSF++ENL DLF AG + L+P++Q +VQ E
Sbjct: 286 EKNRGNAT-SSFHEENLIYSTLDLFFAGTETTSTTLRWGLLYLALNPEIQEKVQAE 340
>ref|XP_541605.2| PREDICTED: similar to cytochrome P450, family 2, subfamily S,
polypeptide 1 [Canis familiaris].
Length = 494
Score = 117 bits (292), Expect(2) = 9e-32
Identities = 78/230 (33%), Positives = 112/230 (48%), Gaps = 2/230 (0%)
Frame = +1
Query: 265 IQLRRRFGDVFSLQQ-IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSE 441
++L +++G VF++ WR VVVL G AV+EAL + E S R + L+ G
Sbjct: 57 LRLSKKYGPVFTVYLGPWRRVVVLVGHEAVQEALGGQAEEFSGRGMLATLDGTFGG---H 113
Query: 442 GVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNL 621
GV + G+ WR+ RR + LR+ G+GK+ EE + EA L AF GRPF P+ L
Sbjct: 114 GVFFSN-GERWRQLRRLTTLALRDLGMGKREGEELIQAEAQSLVEAFQGTVGRPFDPSLL 172
Query: 622 LNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGL 798
L +A SN+I SLTF RF Y D Q E +L+H+PG
Sbjct: 173 LAQATSNIICSLTFGLRFPYEDKEFQAVVQAAGGTVLGVSSPWGQTYEMFSWLLQHLPGP 232
Query: 799 CAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
+L + + HK + D + PP D+ DAFL +M + + P
Sbjct: 233 HTQLLSHLSVLATFAVQQVQRHKESLDTSGPPHDVVDAFLLKMAKEEQDP 282
Score = 39.3 bits (90), Expect(2) = 9e-32
Identities = 24/77 (31%), Positives = 37/77 (48%)
Frame = +3
Query: 942 ETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARA 1121
+ P + D+NL + V L AG + ++ +P VQ RV++E A
Sbjct: 280 QDPNTELTDKNLLMTVIYLLFAGTVTVSTTVRYTLLLLLKYPQVQERVREELSRELGAGR 339
Query: 1122 ATGKKDQALMPFTLAVL 1172
A G D+A +P+T AVL
Sbjct: 340 APGLGDRARLPYTDAVL 356
>ref|NP_001183973.1| cytochrome P450 2C21 [Canis lupus familiaris].
Length = 490
Score = 111 bits (277), Expect(2) = 1e-29
Identities = 78/237 (32%), Positives = 117/237 (49%), Gaps = 1/237 (0%)
Frame = +1
Query: 232 QVNFQDPRLSFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFIL 411
Q+N ++ S +L +G VF++ +P VVL G AV+EAL+ S E S R +L
Sbjct: 44 QINTKNVSKSLSKLAENYGPVFTVYFGMKPTVVLYGYEAVKEALIDRSEEFSGRGHFPLL 103
Query: 412 EHLGYGPRSEGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQ 591
+ G G++ + G+ W++ RRFS++ LRN G+GKK++E+ + +EA L A
Sbjct: 104 DWTIQGL---GIVFSN-GEKWKQTRRFSLTVLRNMGMGKKTVEDRIQEEALYLVEALKKT 159
Query: 592 AGRPFSPNNLLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAM 771
P P LL A NVI S+ F RFEY+D Q+ A
Sbjct: 160 NASPCDPTFLLGCAPCNVICSIIFQNRFEYDDKDFLTLLEYFHENLLISSTSWIQLYNAF 219
Query: 772 PVLRH-IPGLCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAK 939
P+L H +PG LF I E I EH+ + + + PRD D FL ++++ K
Sbjct: 220 PLLIHYLPGSHHVLFKNIANQFKFISEKIKEHEESLNFSN-PRDFIDYFLIKIEKEK 275
Score = 37.7 bits (86), Expect(2) = 1e-29
Identities = 22/74 (29%), Positives = 37/74 (50%)
Frame = +3
Query: 951 ESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARAATG 1130
+S F +NL + + D+FSAG ++ HPDV +VQ+E +
Sbjct: 279 QSEFTMDNLIITIWDVFSAGTETTSTTLRYGLLVLLKHPDVTAKVQEEIHRVVGRHRSPC 338
Query: 1131 KKDQALMPFTLAVL 1172
+D++ MP+T AV+
Sbjct: 339 MQDRSCMPYTDAVV 352
>ref|XP_533661.2| PREDICTED: similar to cytochrome P450 monooxygenase CYP2T1 [Canis
familiaris].
Length = 495
Score = 127 bits (319), Expect = 2e-29
Identities = 77/231 (33%), Positives = 116/231 (50%), Gaps = 1/231 (0%)
Frame = +1
Query: 259 SFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRS 438
+ ++L R+G VF+++ RP VVL G +A+R+ALV + S R + + E +G
Sbjct: 58 ALMELSGRWGPVFTVRLGPRPAVVLCGYSALRDALVLQADAFSGRGAMAVFERFTHG--- 114
Query: 439 EGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNN 618
G++ + G WR R F++ L+ FGLG +++EE + +EA+CL F G PF P
Sbjct: 115 NGIVFSN-GLRWRTLRNFALGALKEFGLGTRTIEERILEEAACLLGEFQATTGAPFDPRR 173
Query: 619 LLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPG 795
LL AVSNVI S+ F R+ Y DP ++ P +L +PG
Sbjct: 174 LLGNAVSNVICSVVFGNRYGYEDPEFQRLLDLFNDNFRIMSSRWGEMYNVFPTLLDWLPG 233
Query: 796 LCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
++F V I E I H+ TR + PRD D FLD+M + + P
Sbjct: 234 PHHRIFQNFTELRVFISEQIQRHQQTRQPGK-PRDFIDCFLDQMDKEQNDP 283
>ref|XP_852606.1| PREDICTED: similar to cytochrome P450, family 2, subfamily K,
polypeptide 6 [Canis familiaris].
Length = 558
Score = 114 bits (285), Expect(2) = 3e-29
Identities = 67/235 (28%), Positives = 118/235 (50%)
Frame = +1
Query: 235 VNFQDPRLSFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILE 414
+N + P + ++L +++G ++S+Q + VVVL+G V++ALV++ + +R V I E
Sbjct: 113 LNLKRPYQTMLELSQKYGSIYSIQMGPKKVVVLSGYETVKDALVNYGDQFGERSQVPIFE 172
Query: 415 HLGYGPRSEGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQA 594
L G +G++ + +G+ W+ RRFS++TLRNFG+GK+ +E+ + +E L +F
Sbjct: 173 RLFEG---KGIVFS-HGETWKTMRRFSLATLRNFGMGKRIIEDTIIEECQHLIWSFESHR 228
Query: 595 GRPFSPNNLLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP 774
G+PF ++N +V+NVI S+ +RF+Y D + + P
Sbjct: 229 GKPFEVKTVMNASVANVIVSVLLGKRFDYQDTQFLRLLTLIGENVKLIGGPRIALFNMFP 288
Query: 775 VLRHIPGLCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAK 939
VL + + + I +H+ D PR DAFL +E K
Sbjct: 289 VLGFLLKSHKTVLRNRDELFAFIRMTFLDHQHKFD-KNDPRSFIDAFLVRQQEEK 342
Score = 33.5 bits (75), Expect(2) = 3e-29
Identities = 17/56 (30%), Positives = 32/56 (57%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQE 1094
++ + +T + F+DENL +V++LF+AG M+ +P+VQ++V E
Sbjct: 338 QQEEKDTSTTYFSDENLVALVSNLFAAGTETTATTLCWALLLMMRYPEVQKKVCDE 393
>ref|XP_855301.1| PREDICTED: similar to cytochrome P450, family 2, subfamily F,
polypeptide 1 [Canis familiaris].
Length = 582
Score = 123 bits (309), Expect = 3e-28
Identities = 83/242 (34%), Positives = 122/242 (50%), Gaps = 3/242 (1%)
Frame = +1
Query: 232 QVNFQDPRLSFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRP--PVF 405
Q+ QD S +L + +G V+++ R VVVL+G AV+EALV + S R PVF
Sbjct: 120 QLRSQDMLTSLTKLSKEYGSVYTVHLGPRRVVVLSGYQAVKEALVDQGEDFSGRGDYPVF 179
Query: 406 ILEHLGYGPRSEGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFA 585
G G I G W+ RRFSV LRNFG+GK+S+EE + +E S L A
Sbjct: 180 FNFTKGNG------IAFSNGDRWKVLRRFSVQILRNFGMGKRSIEERILEEGSFLLAELR 233
Query: 586 DQAGRPFSPNNLLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLE 765
G+PF P +L+++VSN+I S+ F RF+Y+D R+ ++
Sbjct: 234 KTEGKPFDPTFVLSRSVSNIICSVIFGSRFDYDDERLLTIIRLINDNFQIMSGPWGELYN 293
Query: 766 AMP-VLRHIPGLCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAKG 942
P +L IPG +LF +I + +H+ + D + PRD D FL++M + K
Sbjct: 294 IFPSLLDWIPGPHRRLFQNFGCMKDLIARSVRDHQDSLD-PRCPRDFIDCFLNKMAQEKQ 352
Query: 943 KP 948
P
Sbjct: 353 DP 354
>ref|NP_001003334.1| cytochrome P450 2C41 [Canis lupus familiaris].
Length = 489
Score = 106 bits (264), Expect(2) = 6e-28
Identities = 78/237 (32%), Positives = 107/237 (45%), Gaps = 1/237 (0%)
Frame = +1
Query: 244 QDPRLSFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLG 423
+D S L + +G VF+L +P VVL+G AV+E L+ E S R I E +
Sbjct: 47 KDINKSLSNLSKAYGPVFTLYFGMKPTVVLHGYDAVKETLIDLGEEFSARGRFPIAEKVS 106
Query: 424 YGPRSEGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRP 603
G G+I G W+E RRF+++TLRN G+GK LE V +EA L P
Sbjct: 107 GG---HGIIFTS-GNRWKEMRRFALTTLRNLGMGKSDLESRVQEEACYLVEELRKTNALP 162
Query: 604 FSPNNLLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLR 783
P +L A NVI S+ F RF+Y D + Q + P L
Sbjct: 163 CDPTFVLGCASCNVICSIIFQNRFDYTDQTLIGFLEKLNENFRILSSPWIQAYNSFPALL 222
Query: 784 H-IPGLCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKPP 951
H +PG +F I E I EH+ + D+ PRD D FL +M++ K P
Sbjct: 223 HYLPGSHNTIFKNFAFIKSYILEKIKEHQESFDV-NNPRDFIDYFLIKMEQEKHNQP 278
Score = 37.4 bits (85), Expect(2) = 6e-28
Identities = 22/71 (30%), Positives = 34/71 (47%)
Frame = +3
Query: 960 FNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARAATGKKD 1139
F ENL+ + DLF AG ++ HP+V +VQ+E + +D
Sbjct: 281 FTFENLKTIATDLFGAGTETTSTTLRYGLLLLLKHPEVTVKVQEEIDRVIGRHQSPHMQD 340
Query: 1140 QALMPFTLAVL 1172
++ MP+T AVL
Sbjct: 341 RSRMPYTNAVL 351
>ref|NP_001006653.1| cytochrome P450 2B11 [Canis lupus familiaris].
Length = 494
Score = 120 bits (301), Expect = 2e-27
Identities = 72/231 (31%), Positives = 119/231 (51%), Gaps = 1/231 (0%)
Frame = +1
Query: 259 SFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRS 438
SF++L+ ++GDVF++ R V+L G+ A+REALV ++ S R + ++E + G
Sbjct: 54 SFLRLQEKYGDVFTVYLGPRRTVMLCGIDAIREALVDNAEAFSGRGKIAVVEPVFQG--- 110
Query: 439 EGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNN 618
GV+ A G+ W+ RRFS++T+R+FG+GK+S+EE + +EA CL G P
Sbjct: 111 YGVVFAN-GERWKTLRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKTEGVLQDPTF 169
Query: 619 LLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAM-PVLRHIPG 795
+ +N+I S+ F +RF Y DP Q+ E L++ PG
Sbjct: 170 FFHSMTANIICSIVFGKRFGYKDPEFLRLMNLFYVSFALISSFSSQMFELFHSFLKYFPG 229
Query: 796 LCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
+++ + I ++ +H+ T D PRD DA+L M + K +P
Sbjct: 230 THRQVYNNLQEIKAFIARMVEKHRETLD-PSAPRDFIDAYLIRMDKEKAEP 279
>ref|XP_855605.1| PREDICTED: cytochrome P450 2B11 [Canis familiaris].
Length = 494
Score = 120 bits (301), Expect = 2e-27
Identities = 72/231 (31%), Positives = 119/231 (51%), Gaps = 1/231 (0%)
Frame = +1
Query: 259 SFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRS 438
SF++L+ ++GDVF++ R V+L G+ A+REALV ++ S R + ++E + G
Sbjct: 54 SFLRLQEKYGDVFTVYLGPRRTVMLCGIDAIREALVDNAEAFSGRGKIAVVEPVFQG--- 110
Query: 439 EGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNN 618
GV+ A G+ W+ RRFS++T+R+FG+GK+S+EE + +EA CL G P
Sbjct: 111 YGVVFAN-GERWKTLRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKTEGVLQDPTF 169
Query: 619 LLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAM-PVLRHIPG 795
+ +N+I S+ F +RF Y DP Q+ E L++ PG
Sbjct: 170 FFHSMTANIICSIVFGKRFGYKDPEFLRLMNLFYVSFALISSFSSQMFELFHSFLKYFPG 229
Query: 796 LCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
+++ + I ++ +H+ T D PRD DA+L M + K +P
Sbjct: 230 THRQVYNNLQEIKAFIARMVEKHRETLD-PSAPRDFIDAYLIRMDKEKAEP 279
Database: RefSeq49_CP.fasta
Posted date: Oct 17, 2011 1:42 PM
Number of letters in database: 18,874,504
Number of sequences in database: 33,336
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33336
Number of Hits to DB: 44,483,827
Number of extensions: 1161390
Number of successful extensions: 4044
Number of sequences better than 1.0e-05: 23
Number of HSP's gapped: 4011
Number of HSP's successfully gapped: 33
Length of query: 390
Length of database: 18,874,504
Length adjustment: 105
Effective length of query: 285
Effective length of database: 15,374,224
Effective search space: 4381653840
Effective search space used: 4381653840
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)
Search to RefSeqHP_Rel49
BLASTX 2.2.24 [Aug-08-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20110601C-006978
(1172 letters)
Database: RefSeq49_HP.fasta
32,964 sequences; 18,297,164 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_000097.2| cytochrome P450 2D6 isoform 1 [Homo sapiens]. 347 e-111
Alignment gi|NP_001020332.1| cytochrome P450 2D6 isoform 2 [Homo sapiens]. 235 5e-78
Alignment gi|NP_000766.2| cytochrome P450 2J2 [Homo sapiens]. 140 1e-38
Alignment gi|NP_898898.1| cytochrome P450 2U1 [Homo sapiens]. 115 2e-32
Alignment gi|NP_000761.3| cytochrome P450 2C8 isoform a [Homo sapiens]. 117 2e-31
Alignment gi|NP_085125.1| cytochrome P450 2S1 [Homo sapiens]. 120 2e-30
Alignment gi|NP_000765.2| cytochrome P450 2F1 [Homo sapiens]. 119 5e-30
Alignment gi|NP_000760.1| cytochrome P450 2C19 [Homo sapiens]. 114 6e-30
Alignment gi|NP_001185784.1| cytochrome P450 2C8 isoform b [Homo sapiens]. 107 1e-28
Alignment gi|NP_001185782.1| cytochrome P450 2C8 isoform b [Homo sapiens]. 107 1e-28
>ref|NP_000097.2| cytochrome P450 2D6 isoform 1 [Homo sapiens].
Length = 497
Score = 347 bits (890), Expect(2) = e-111
Identities = 177/274 (64%), Positives = 203/274 (74%)
Frame = +1
Query: 127 MVIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQ 306
+ IFLLLVDLMHRR RWA RY V+FQ+ F QLRRRFGDVFSLQ
Sbjct: 13 VAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQ 72
Query: 307 QIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQR 486
W PVVVLNGLAAVREALV+H +T+DRPPV I + LG+GPRS+GV LARYG AWREQR
Sbjct: 73 LAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQR 132
Query: 487 RFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFA 666
RFSVSTLRN GLGKKSLE+WVT+EA+CLCAAFA+ +GRPF PN LL+KAVSNVIASLT
Sbjct: 133 RFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCG 192
Query: 667 RRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMID 846
RRFEY+DPR +R+VL A+PVL HIP L K+ QKAFL +D
Sbjct: 193 RRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLD 252
Query: 847 ELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
EL+TEH+MT D AQPPRDLT+AFL EM++AKG P
Sbjct: 253 ELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNP 286
Score = 75.5 bits (184), Expect(2) = e-111
Identities = 47/84 (55%), Positives = 54/84 (64%), Gaps = 2/84 (2%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQE--NQ 1100
E+ +G PESSFNDENL +VVADLFSAGM+ MILHPDVQRRVQQE +
Sbjct: 280 EKAKGN-PESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDV 338
Query: 1101 *GDRARAATGKKDQALMPFTLAVL 1172
G R G DQA MP+T AV+
Sbjct: 339 IGQVRRPEMG--DQAHMPYTTAVI 360
>ref|NP_001020332.1| cytochrome P450 2D6 isoform 2 [Homo sapiens].
Length = 446
Score = 235 bits (600), Expect(2) = 5e-78
Identities = 135/274 (49%), Positives = 156/274 (56%)
Frame = +1
Query: 127 MVIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQ 306
+ IFLLLVDLMHRR RWA RY V+FQ+ F QLRRRFGDVFSLQ
Sbjct: 13 VAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQ 72
Query: 307 QIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQR 486
W PVVVLNGLAAVREALV+H +T+DRPPV I + LG+GPRS+
Sbjct: 73 LAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQ--------------- 117
Query: 487 RFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFA 666
GRPF PN LL+KAVSNVIASLT
Sbjct: 118 ------------------------------------GRPFRPNGLLDKAVSNVIASLTCG 141
Query: 667 RRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMID 846
RRFEY+DPR +R+VL A+PVL HIP L K+ QKAFL +D
Sbjct: 142 RRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLD 201
Query: 847 ELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
EL+TEH+MT D AQPPRDLT+AFL EM++AKG P
Sbjct: 202 ELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNP 235
Score = 75.5 bits (184), Expect(2) = 5e-78
Identities = 47/84 (55%), Positives = 54/84 (64%), Gaps = 2/84 (2%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQE--NQ 1100
E+ +G PESSFNDENL +VVADLFSAGM+ MILHPDVQRRVQQE +
Sbjct: 229 EKAKGN-PESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDV 287
Query: 1101 *GDRARAATGKKDQALMPFTLAVL 1172
G R G DQA MP+T AV+
Sbjct: 288 IGQVRRPEMG--DQAHMPYTTAVI 309
>ref|NP_000766.2| cytochrome P450 2J2 [Homo sapiens].
Length = 502
Score = 140 bits (354), Expect(2) = 1e-38
Identities = 89/274 (32%), Positives = 138/274 (50%), Gaps = 1/274 (0%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQ 309
V FLL D + RR Y V+F+ L +++G++FSL+
Sbjct: 26 VAFLLAADFLKRRR--PKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLEL 83
Query: 310 IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRR 489
V++ GL ++EAL+ +RP + EH+ + G+I++ G+AW+EQRR
Sbjct: 84 GDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIF---KKNGLIMSS-GQAWKEQRR 139
Query: 490 FSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFAR 669
F+++ LRNFGLGKKSLEE + +EA L A ++ G+PF P+ +N AVSN+I S+TF
Sbjct: 140 FTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGE 199
Query: 670 RFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGLCAKLFPRQKAFLVMID 846
RFEY D Q+ P +++ +PG LF K + +
Sbjct: 200 RFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLPGPHQTLFSNWKKLKLFVS 259
Query: 847 ELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
+I +H+ + A+ RD DA+L EM + G P
Sbjct: 260 HMIDKHRKDWNPAE-TRDFIDAYLKEMSKHTGNP 292
Score = 38.5 bits (88), Expect(2) = 1e-38
Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Frame = +3
Query: 948 PESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQE--NQ*GDRARA 1121
P SSF++ENL DLF AG M L+P++Q +VQ E G +
Sbjct: 292 PTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQP 351
Query: 1122 ATGKKDQALMPFTLAVL 1172
+T ++ MP+T AV+
Sbjct: 352 STAARES--MPYTNAVI 366
>ref|NP_898898.1| cytochrome P450 2U1 [Homo sapiens].
Length = 544
Score = 115 bits (288), Expect(2) = 2e-32
Identities = 75/231 (32%), Positives = 119/231 (51%), Gaps = 1/231 (0%)
Frame = +1
Query: 250 PRLSFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYG 429
P++ L R +G +FS VVVL+ +VREALV + SDRP V ++ +
Sbjct: 103 PQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIV--- 159
Query: 430 PRSEGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFS 609
+ +GV+ A YG WR+QR+FS STLR+FGLGK SLE + +E + A PF
Sbjct: 160 TKEKGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFKYVKAEMQKHGEDPFC 219
Query: 610 PNNLLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHI 789
P ++++ AVSN+I SL F +RF+Y + ++ P L ++
Sbjct: 220 PFSIISNAVSNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWLYYL 279
Query: 790 P-GLCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAK 939
P G +L +K + ++I +H+ + D + P+D D +L M+E +
Sbjct: 280 PFGPFKELRQIEKDITSFLKKIIKDHQESLD-RENPQDFIDMYLLHMEEER 329
Score = 43.1 bits (100), Expect(2) = 2e-32
Identities = 27/82 (32%), Positives = 39/82 (47%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*G 1106
E + SSF++E L ++ DLF AG M L+PDVQ +V +E +
Sbjct: 326 EEERKNNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERV 385
Query: 1107 DRARAATGKKDQALMPFTLAVL 1172
A A D+A MP+T A +
Sbjct: 386 IGANRAPSLTDKAQMPYTEATI 407
>ref|NP_000761.3| cytochrome P450 2C8 isoform a [Homo sapiens].
Length = 490
Score = 117 bits (292), Expect(2) = 2e-31
Identities = 79/242 (32%), Positives = 116/242 (47%), Gaps = 6/242 (2%)
Frame = +1
Query: 232 QVNFQDPRLSFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFIL 411
Q++ +D SF + +G VF++ P+VV +G AV+EAL+ + E S R
Sbjct: 44 QIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGR------ 97
Query: 412 EHLGYGPRSEGV-----ILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCA 576
G P S+ + I++ GK W+E RRFS++TLRNFG+GK+S+E+ V +EA CL
Sbjct: 98 ---GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVE 154
Query: 577 AFADQAGRPFSPNNLLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQ 756
P P +L A NVI S+ F +RF+Y D Q
Sbjct: 155 ELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQ 214
Query: 757 VLEAMPVLRH-IPGLCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKE 933
V P+L PG K+ I E + EH+ + D+ PRD D FL +M++
Sbjct: 215 VCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDV-NNPRDFIDCFLIKMEQ 273
Query: 934 AK 939
K
Sbjct: 274 EK 275
Score = 38.5 bits (88), Expect(2) = 2e-31
Identities = 25/77 (32%), Positives = 38/77 (49%)
Frame = +3
Query: 942 ETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARA 1121
+ +S FN ENL VADLF AG ++ HP+V +VQ+E
Sbjct: 276 DNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHR 335
Query: 1122 ATGKKDQALMPFTLAVL 1172
+ +D++ MP+T AV+
Sbjct: 336 SPCMQDRSHMPYTDAVV 352
>ref|NP_085125.1| cytochrome P450 2S1 [Homo sapiens].
Length = 504
Score = 120 bits (302), Expect(2) = 2e-30
Identities = 81/230 (35%), Positives = 112/230 (48%), Gaps = 2/230 (0%)
Frame = +1
Query: 265 IQLRRRFGDVFSLQQ-IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSE 441
++L +++G VF++ WRPVVVL G AVREAL + E S R V +LE G
Sbjct: 58 MRLSKKYGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDG---H 114
Query: 442 GVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNL 621
GV + G+ WR+ R+F++ LR+ G+GK+ EE + EA CL F GRPF P+ L
Sbjct: 115 GVFFSN-GERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSLL 173
Query: 622 LNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGL 798
L +A SNV+ SL F RF Y D Q E LR +PG
Sbjct: 174 LAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGGTLLGVSSQGGQTYEMFSWFLRPLPGP 233
Query: 799 CAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
+L + +H+ D + P RDL DAFL +M + + P
Sbjct: 234 HKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQEEQNP 283
Score = 30.8 bits (68), Expect(2) = 2e-30
Identities = 20/77 (25%), Positives = 36/77 (46%)
Frame = +3
Query: 942 ETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARA 1121
+ P + F ++N+ + V L AG + ++ +P VQ+ V++E A
Sbjct: 281 QNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQ 340
Query: 1122 ATGKKDQALMPFTLAVL 1172
A D+ +P+T AVL
Sbjct: 341 APSLGDRTRLPYTDAVL 357
>ref|NP_000765.2| cytochrome P450 2F1 [Homo sapiens].
Length = 491
Score = 119 bits (298), Expect(2) = 5e-30
Identities = 78/238 (32%), Positives = 118/238 (49%), Gaps = 3/238 (1%)
Frame = +1
Query: 244 QDPRLSFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRP--PVFILEH 417
QD S +L + +G ++++ R VVVL+G AV+EALV E S R P F
Sbjct: 49 QDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFT 108
Query: 418 LGYGPRSEGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAG 597
G G I G W+ R+FS+ LRNFG+GK+S+EE + +E S L A G
Sbjct: 109 KGNG------IAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEEGSFLLAELRKTEG 162
Query: 598 RPFSPNNLLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP- 774
PF P +L+++VSN+I S+ F RF+Y+D R+ ++ + P
Sbjct: 163 EPFDPTFVLSRSVSNIICSVLFGSRFDYDDERLLTIIRLINDNFQIMSSPWGELYDIFPS 222
Query: 775 VLRHIPGLCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
+L +PG ++F K +I + +H+ + D + PRD FL +M E K P
Sbjct: 223 LLDWVPGPHQRIFQNFKCLRDLIAHSVHDHQASLD-PRSPRDFIQCFLTKMAEEKEDP 279
Score = 31.2 bits (69), Expect(2) = 5e-30
Identities = 22/77 (28%), Positives = 33/77 (42%)
Frame = +3
Query: 942 ETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARA 1121
E P S F+ + L + +L G ++ +P VQ RVQ+E
Sbjct: 277 EDPLSHFHMDTLLMTTHNLLFGGTKTVSTTLHHAFLALMKYPKVQARVQEEIDLVVGRAR 336
Query: 1122 ATGKKDQALMPFTLAVL 1172
KD+A MP+T AV+
Sbjct: 337 LPALKDRAAMPYTDAVI 353
>ref|NP_000760.1| cytochrome P450 2C19 [Homo sapiens].
Length = 490
Score = 114 bits (284), Expect(2) = 6e-30
Identities = 77/237 (32%), Positives = 114/237 (48%), Gaps = 1/237 (0%)
Frame = +1
Query: 232 QVNFQDPRLSFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFIL 411
Q++ +D S L + +G VF+L +VVL+G V+EAL+ E S R +
Sbjct: 44 QIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLA 103
Query: 412 EHLGYGPRSEGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQ 591
E R G++ + GK W+E RRFS+ TLRNFG+GK+S+E+ V +EA CL
Sbjct: 104 ERAN---RGFGIVFSN-GKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKT 159
Query: 592 AGRPFSPNNLLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAM 771
P P +L A NVI S+ F +RF+Y D + Q+
Sbjct: 160 KASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLMEKLNENIRIVSTPWIQICNNF 219
Query: 772 P-VLRHIPGLCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAK 939
P ++ + PG KL I E + EH+ + D+ PRD D FL +M++ K
Sbjct: 220 PTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMDI-NNPRDFIDCFLIKMEKEK 275
Score = 36.2 bits (82), Expect(2) = 6e-30
Identities = 22/77 (28%), Positives = 36/77 (46%)
Frame = +3
Query: 942 ETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARA 1121
+ +S F ENL + ADL AG ++ HP+V +VQ+E +
Sbjct: 276 QNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNR 335
Query: 1122 ATGKKDQALMPFTLAVL 1172
+ +D+ MP+T AV+
Sbjct: 336 SPCMQDRGHMPYTDAVV 352
>ref|NP_001185784.1| cytochrome P450 2C8 isoform b [Homo sapiens].
Length = 420
Score = 107 bits (267), Expect(2) = 1e-28
Identities = 72/213 (33%), Positives = 102/213 (47%), Gaps = 6/213 (2%)
Frame = +1
Query: 319 PVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGV-----ILARYGKAWREQ 483
P+VV +G AV+EAL+ + E S R G P S+ + I++ GK W+E
Sbjct: 3 PIVVFHGYEAVKEALIDNGEEFSGR---------GNSPISQRITKGLGIISSNGKRWKEI 53
Query: 484 RRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTF 663
RRFS++TLRNFG+GK+S+E+ V +EA CL P P +L A NVI S+ F
Sbjct: 54 RRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVF 113
Query: 664 ARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRH-IPGLCAKLFPRQKAFLVM 840
+RF+Y D QV P+L PG K+
Sbjct: 114 QKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSY 173
Query: 841 IDELITEHKMTRDLAQPPRDLTDAFLDEMKEAK 939
I E + EH+ + D+ PRD D FL +M++ K
Sbjct: 174 IREKVKEHQASLDV-NNPRDFIDCFLIKMEQEK 205
Score = 38.5 bits (88), Expect(2) = 1e-28
Identities = 25/77 (32%), Positives = 38/77 (49%)
Frame = +3
Query: 942 ETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARA 1121
+ +S FN ENL VADLF AG ++ HP+V +VQ+E
Sbjct: 206 DNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHR 265
Query: 1122 ATGKKDQALMPFTLAVL 1172
+ +D++ MP+T AV+
Sbjct: 266 SPCMQDRSHMPYTDAVV 282
>ref|NP_001185782.1| cytochrome P450 2C8 isoform b [Homo sapiens].
Length = 420
Score = 107 bits (267), Expect(2) = 1e-28
Identities = 72/213 (33%), Positives = 102/213 (47%), Gaps = 6/213 (2%)
Frame = +1
Query: 319 PVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGV-----ILARYGKAWREQ 483
P+VV +G AV+EAL+ + E S R G P S+ + I++ GK W+E
Sbjct: 3 PIVVFHGYEAVKEALIDNGEEFSGR---------GNSPISQRITKGLGIISSNGKRWKEI 53
Query: 484 RRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTF 663
RRFS++TLRNFG+GK+S+E+ V +EA CL P P +L A NVI S+ F
Sbjct: 54 RRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVF 113
Query: 664 ARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRH-IPGLCAKLFPRQKAFLVM 840
+RF+Y D QV P+L PG K+
Sbjct: 114 QKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSY 173
Query: 841 IDELITEHKMTRDLAQPPRDLTDAFLDEMKEAK 939
I E + EH+ + D+ PRD D FL +M++ K
Sbjct: 174 IREKVKEHQASLDV-NNPRDFIDCFLIKMEQEK 205
Score = 38.5 bits (88), Expect(2) = 1e-28
Identities = 25/77 (32%), Positives = 38/77 (49%)
Frame = +3
Query: 942 ETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARA 1121
+ +S FN ENL VADLF AG ++ HP+V +VQ+E
Sbjct: 206 DNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHR 265
Query: 1122 ATGKKDQALMPFTLAVL 1172
+ +D++ MP+T AV+
Sbjct: 266 SPCMQDRSHMPYTDAVV 282
Database: RefSeq49_HP.fasta
Posted date: Oct 17, 2011 1:42 PM
Number of letters in database: 18,297,164
Number of sequences in database: 32,964
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 32964
Number of Hits to DB: 43,517,387
Number of extensions: 1130127
Number of successful extensions: 4108
Number of sequences better than 1.0e-05: 26
Number of HSP's gapped: 4061
Number of HSP's successfully gapped: 42
Length of query: 390
Length of database: 18,297,164
Length adjustment: 104
Effective length of query: 286
Effective length of database: 14,868,908
Effective search space: 4252507688
Effective search space used: 4252507688
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)
Search to RefSeqMP_Rel49
BLASTX 2.2.24 [Aug-08-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20110601C-006978
(1172 letters)
Database: RefSeq49_MP.fasta
30,036 sequences; 15,617,559 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_001156944.1| cytochrome P450, family 2, subfamily d, poly... 303 4e-98
Alignment gi|NP_062797.3| cytochrome P450, family 2, subfamily d, polypep... 303 4e-98
Alignment gi|NP_663449.2| cytochrome P450, family 2, subfamily d, polypep... 277 3e-89
Alignment gi|NP_034136.2| cytochrome P450 2D9 [Mus musculus]. 278 6e-89
Alignment gi|NP_034135.2| cytochrome P450 2D10 [Mus musculus]. 277 1e-88
Alignment gi|NP_958748.1| cytochrome P450, family 2, subfamily d, polypep... 273 8e-88
Alignment gi|NP_001098001.1| cytochrome P450 2D11 [Mus musculus]. 268 2e-87
Alignment gi|NP_083838.1| cytochrome P450 2D26 [Mus musculus]. 295 4e-80
Alignment gi|NP_034138.3| cytochrome P450 2J6 [Mus musculus]. 147 3e-41
Alignment gi|NP_083255.1| cytochrome P450, family 2, subfamily j, polypep... 144 2e-34
>ref|NP_001156944.1| cytochrome P450, family 2, subfamily d, polypeptide 22 [Mus
musculus].
Length = 500
Score = 303 bits (777), Expect(2) = 4e-98
Identities = 152/273 (55%), Positives = 188/273 (68%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQ 309
VIFL+LV+LMH R RW Y ++FQ+ F +LR R+GD+FSLQ
Sbjct: 17 VIFLILVNLMHWRQRWTAHYPPGPMPWPVLGNLLHMDFQNMPAGFQKLRGRYGDLFSLQL 76
Query: 310 IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRR 489
VVVLNGL A+REALV HS +T+DRPP+ + LG+GPRS+G++LARYG AWR+QRR
Sbjct: 77 ASESVVVLNGLTALREALVKHSEDTADRPPLHFNDLLGFGPRSQGIVLARYGPAWRQQRR 136
Query: 490 FSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFAR 669
FSVST+ +FGLGKKSLE+WVT+EA CLCAAFAD G PFSPN LL+KAV NVIASL +A
Sbjct: 137 FSVSTMHHFGLGKKSLEQWVTEEARCLCAAFADHTGHPFSPNTLLDKAVCNVIASLLYAC 196
Query: 670 RFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMIDE 849
RFEY+DPR + L P+L IPGL K+FP ++AF+ M+DE
Sbjct: 197 RFEYDDPRFIRLLGLLKETLKEEAGFLPMFLNVFPMLLRIPGLVGKVFPGKRAFVTMLDE 256
Query: 850 LITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
L+ EHK T D QPPRDLTDAFL E+++AKG P
Sbjct: 257 LLAEHKTTWDPTQPPRDLTDAFLAEVEKAKGNP 289
Score = 73.9 bits (180), Expect(2) = 4e-98
Identities = 44/82 (53%), Positives = 49/82 (59%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*G 1106
E+ +G PESSFNDENLR VV DLFSAGM+ MILHPDVQRRVQQE
Sbjct: 283 EKAKGN-PESSFNDENLRTVVGDLFSAGMVTTSTTLSWALMLMILHPDVQRRVQQEIDEV 341
Query: 1107 DRARAATGKKDQALMPFTLAVL 1172
DQA MP+T AV+
Sbjct: 342 IGQVQCPEMADQARMPYTNAVI 363
>ref|NP_062797.3| cytochrome P450, family 2, subfamily d, polypeptide 22 [Mus
musculus].
Length = 500
Score = 303 bits (777), Expect(2) = 4e-98
Identities = 152/273 (55%), Positives = 188/273 (68%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQ 309
VIFL+LV+LMH R RW Y ++FQ+ F +LR R+GD+FSLQ
Sbjct: 17 VIFLILVNLMHWRQRWTAHYPPGPMPWPVLGNLLHMDFQNMPAGFQKLRGRYGDLFSLQL 76
Query: 310 IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRR 489
VVVLNGL A+REALV HS +T+DRPP+ + LG+GPRS+G++LARYG AWR+QRR
Sbjct: 77 ASESVVVLNGLTALREALVKHSEDTADRPPLHFNDLLGFGPRSQGIVLARYGPAWRQQRR 136
Query: 490 FSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFAR 669
FSVST+ +FGLGKKSLE+WVT+EA CLCAAFAD G PFSPN LL+KAV NVIASL +A
Sbjct: 137 FSVSTMHHFGLGKKSLEQWVTEEARCLCAAFADHTGHPFSPNTLLDKAVCNVIASLLYAC 196
Query: 670 RFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMIDE 849
RFEY+DPR + L P+L IPGL K+FP ++AF+ M+DE
Sbjct: 197 RFEYDDPRFIRLLGLLKETLKEEAGFLPMFLNVFPMLLRIPGLVGKVFPGKRAFVTMLDE 256
Query: 850 LITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
L+ EHK T D QPPRDLTDAFL E+++AKG P
Sbjct: 257 LLAEHKTTWDPTQPPRDLTDAFLAEVEKAKGNP 289
Score = 73.9 bits (180), Expect(2) = 4e-98
Identities = 44/82 (53%), Positives = 49/82 (59%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*G 1106
E+ +G PESSFNDENLR VV DLFSAGM+ MILHPDVQRRVQQE
Sbjct: 283 EKAKGN-PESSFNDENLRTVVGDLFSAGMVTTSTTLSWALMLMILHPDVQRRVQQEIDEV 341
Query: 1107 DRARAATGKKDQALMPFTLAVL 1172
DQA MP+T AV+
Sbjct: 342 IGQVQCPEMADQARMPYTNAVI 363
>ref|NP_663449.2| cytochrome P450, family 2, subfamily d, polypeptide 34 [Mus
musculus].
Length = 504
Score = 277 bits (709), Expect(2) = 3e-89
Identities = 141/273 (51%), Positives = 180/273 (65%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQ 309
VIFL+LVDLMHRR W RY QV+ + S +L+ R+GDVFSLQ
Sbjct: 17 VIFLILVDLMHRRQHWTSRYPPGPVPWPVLGNLLQVDLDNIPYSLYKLQNRYGDVFSLQM 76
Query: 310 IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRR 489
W+PVVV+NGL A++E L++ +T+D PPV I E+LG+ +S+GV+LA YG WREQR+
Sbjct: 77 AWKPVVVINGLKAMQEVLLTCGKDTADHPPVPIFEYLGFKSKSQGVVLASYGPEWREQRQ 136
Query: 490 FSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFAR 669
FSVSTLRNFGLGKKSLEEWVT+EA LC AF +AG+ +PN +LN AV NVIASL FAR
Sbjct: 137 FSVSTLRNFGLGKKSLEEWVTKEAKHLCDAFTARAGQSINPNTMLNNAVCNVIASLIFAR 196
Query: 670 RFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMIDE 849
RFEY DP + + VL P+L IPGL +F QK F+ ++D
Sbjct: 197 RFEYEDPFLIRMLKMREESLKEVTGFIPGVLNTFPILLRIPGLADMVFQSQKTFMAILDN 256
Query: 850 LITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
L+TE++ T D QPPR+L DAFL E+++AKG P
Sbjct: 257 LVTENRTTWDPDQPPRNLADAFLAEIQKAKGNP 289
Score = 70.5 bits (171), Expect(2) = 3e-89
Identities = 40/75 (53%), Positives = 46/75 (61%)
Frame = +3
Query: 948 PESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARAAT 1127
PESSFNDENL +VV+DLF+AGM+ MILHPDVQRRVQQE
Sbjct: 289 PESSFNDENLCMVVSDLFTAGMVTTSTTLSCALLLMILHPDVQRRVQQEIDAVIGQVRCP 348
Query: 1128 GKKDQALMPFTLAVL 1172
DQA MP+T AV+
Sbjct: 349 EMADQARMPYTNAVI 363
>ref|NP_034136.2| cytochrome P450 2D9 [Mus musculus].
Length = 504
Score = 278 bits (711), Expect(2) = 6e-89
Identities = 142/273 (52%), Positives = 183/273 (67%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQ 309
VIF+LLVDL H+R RW RY QV+ + S +L+ R+GDVFSLQ
Sbjct: 17 VIFILLVDLTHQRQRWTSRYPPGPVPWPVLGNLLQVDLGNMPYSLYKLQNRYGDVFSLQM 76
Query: 310 IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRR 489
W+P+VV+NGL A++E L++ +T+DRPPV I E+LG P S+GV+LA YG WREQRR
Sbjct: 77 AWKPMVVINGLKAMKEMLLTCGEDTADRPPVPIFEYLGVKPGSQGVVLAPYGPEWREQRR 136
Query: 490 FSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFAR 669
FSVSTLRNFGLGKKSLE+WVT+EA+ LC AF QAG+P +PN +LNK+ NVIASL FAR
Sbjct: 137 FSVSTLRNFGLGKKSLEDWVTKEANHLCDAFTAQAGQPINPNPMLNKSTCNVIASLIFAR 196
Query: 670 RFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMIDE 849
RFEY DP + + +VL A P+L IP L K QK+F+ ++D
Sbjct: 197 RFEYEDPFLIRMLKVLEQSLTEVSGLIPEVLNAFPILLRIPRLADKALQGQKSFIAILDN 256
Query: 850 LITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
L+TE++ T D Q PR+LTDAFL E+++AKG P
Sbjct: 257 LLTENRTTWDPVQAPRNLTDAFLAEIEKAKGNP 289
Score = 68.9 bits (167), Expect(2) = 6e-89
Identities = 42/82 (51%), Positives = 48/82 (58%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*G 1106
E+ +G PESSFNDENL +VV DLF AGM+ MILHPDVQRRVQQE
Sbjct: 283 EKAKGN-PESSFNDENLLMVVRDLFGAGMLTTSTTLSWALMLMILHPDVQRRVQQEIDEV 341
Query: 1107 DRARAATGKKDQALMPFTLAVL 1172
DQA MP+T AV+
Sbjct: 342 IGQVRHPEMADQAHMPYTNAVI 363
>ref|NP_034135.2| cytochrome P450 2D10 [Mus musculus].
Length = 504
Score = 277 bits (708), Expect(2) = 1e-88
Identities = 142/271 (52%), Positives = 181/271 (66%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQ 309
VIF+LLVDLMHR RW RY QV+ + S +L+ R+GDVFSLQ
Sbjct: 17 VIFILLVDLMHRHQRWTSRYPPGPVPWPVLGNLLQVDLDNMPYSLYKLQNRYGDVFSLQM 76
Query: 310 IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRR 489
W+P+VV+NGL A++E L++ +T+DRP V I E+LG P S+GV+LA YG WREQRR
Sbjct: 77 GWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYLGVKPGSQGVVLAPYGPEWREQRR 136
Query: 490 FSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFAR 669
FSVSTLRNFGLGKKSLE+WVT+EA LC AF QAG+P +PN +LN AV NVIASL FAR
Sbjct: 137 FSVSTLRNFGLGKKSLEDWVTKEARHLCDAFTAQAGQPINPNTMLNNAVCNVIASLIFAR 196
Query: 670 RFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMIDE 849
RFEY DP + + +VL P+L IPGL K+F QK+ L +++
Sbjct: 197 RFEYEDPYLIRMQKVLEDSLTEISGLIPEVLNMFPILLRIPGLPGKVFQGQKSLLAIVEN 256
Query: 850 LITEHKMTRDLAQPPRDLTDAFLDEMKEAKG 942
L+TE++ T D QPPR+LTDAFL E+++ KG
Sbjct: 257 LLTENRNTWDPDQPPRNLTDAFLAEIEKVKG 287
Score = 69.3 bits (168), Expect(2) = 1e-88
Identities = 40/74 (54%), Positives = 45/74 (60%)
Frame = +3
Query: 951 ESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARAATG 1130
ESSFNDENLR+VV DLF+AGM+ MILHPDVQRRVQQE
Sbjct: 290 ESSFNDENLRMVVLDLFTAGMVTTSTTLSWALLLMILHPDVQRRVQQEIDAVIGQVRHPE 349
Query: 1131 KKDQALMPFTLAVL 1172
DQA MP+T AV+
Sbjct: 350 MADQARMPYTNAVI 363
>ref|NP_958748.1| cytochrome P450, family 2, subfamily d, polypeptide 12 [Mus
musculus].
Length = 504
Score = 273 bits (697), Expect(2) = 8e-88
Identities = 137/273 (50%), Positives = 179/273 (65%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQ 309
VIF+LLVDLMHRR W Y QV+ + S +L+ R+GDVFSLQ
Sbjct: 17 VIFILLVDLMHRRQSWTSCYPPGPVPWPVLGNLLQVDLNNMPYSLYKLQNRYGDVFSLQM 76
Query: 310 IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRR 489
W+P+VV+N + A++E L++ +T+DRPPV I EHLG+ PRS+G+I A YG WREQRR
Sbjct: 77 AWKPMVVINRMKAMKEVLLTCGEDTADRPPVPIFEHLGFKPRSQGMIFAPYGPEWREQRR 136
Query: 490 FSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFAR 669
FS+S+LRNFGLG+KSLEEWV +EA LC AF QAG+ +PN +L KA NVIASL FAR
Sbjct: 137 FSLSSLRNFGLGRKSLEEWVIKEAGHLCDAFTTQAGQYINPNTMLKKATCNVIASLIFAR 196
Query: 670 RFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMIDE 849
RFEY DP + + +V+ P+L HIP L K QK+F+ ++D
Sbjct: 197 RFEYEDPYLIRMLKVLEDSLTELSGLIPEVINTFPILLHIPRLADKFLQSQKSFIAIVDN 256
Query: 850 LITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
L+TE++ T D AQ PR+LTDAFL E+++AKG P
Sbjct: 257 LLTENRTTWDPAQSPRNLTDAFLAEIEKAKGNP 289
Score = 70.5 bits (171), Expect(2) = 8e-88
Identities = 42/82 (51%), Positives = 50/82 (60%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*G 1106
E+ +G PESSFNDENLR+VV DLF+AG++ MILHPDVQRRVQQE
Sbjct: 283 EKAKGN-PESSFNDENLRMVVIDLFTAGILTTSTTLSWALLLMILHPDVQRRVQQEIDEV 341
Query: 1107 DRARAATGKKDQALMPFTLAVL 1172
DQA MP+T AV+
Sbjct: 342 IGQVRHPEMADQAHMPYTNAVI 363
>ref|NP_001098001.1| cytochrome P450 2D11 [Mus musculus].
Length = 504
Score = 268 bits (686), Expect(2) = 2e-87
Identities = 139/273 (50%), Positives = 178/273 (65%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQ 309
VIF+LLVDLMHR W R QV+ + S +L+ R+GDVFSLQ
Sbjct: 17 VIFILLVDLMHRHQHWTSRCPPGPVPWPVLGNLLQVDLGNMPYSLYKLQNRYGDVFSLQM 76
Query: 310 IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRR 489
W+P+VV+NGL A++E L++ +T+DRP V I E+LG P S+GV+LA YG W+EQRR
Sbjct: 77 GWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYLGVKPGSQGVVLAPYGPEWQEQRR 136
Query: 490 FSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFAR 669
FSVSTLRNFGLGKKSLE+WVT+EA LC AF QAG+ +PN +LN AV NVIASL FAR
Sbjct: 137 FSVSTLRNFGLGKKSLEDWVTKEARHLCDAFTAQAGQSINPNTMLNNAVCNVIASLIFAR 196
Query: 670 RFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMIDE 849
RFEY DP + + VL P+ IPGL +F QK+F+ ++D
Sbjct: 197 RFEYEDPYLIRMLKMLKECFTEISGFIPGVLNEFPIFLRIPGLADMVFQGQKSFMAILDN 256
Query: 850 LITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
L+TE++ T D QPPR+LTDAFL E+++AKG P
Sbjct: 257 LLTENRTTWDPDQPPRNLTDAFLAEIEKAKGNP 289
Score = 73.2 bits (178), Expect(2) = 2e-87
Identities = 43/82 (52%), Positives = 50/82 (60%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*G 1106
E+ +G PESSFNDENLR+VV DLF+AGM+ MILHPDVQRRVQQE
Sbjct: 283 EKAKGN-PESSFNDENLRMVVGDLFTAGMVTTSTTLSWALLLMILHPDVQRRVQQEIDAV 341
Query: 1107 DRARAATGKKDQALMPFTLAVL 1172
DQA MP+T AV+
Sbjct: 342 IGQVQHPEMADQARMPYTNAVI 363
>ref|NP_083838.1| cytochrome P450 2D26 [Mus musculus].
Length = 500
Score = 295 bits (756), Expect = 4e-80
Identities = 167/350 (47%), Positives = 214/350 (61%), Gaps = 17/350 (4%)
Frame = +1
Query: 133 IFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQI 312
IFLLLVDL+HRR RW Y QV+F++ SF +L+ R+G+VFSLQ
Sbjct: 18 IFLLLVDLVHRRQRWTACYPPGPVPFPGLGNLLQVDFENIPYSFYKLQNRYGNVFSLQMA 77
Query: 313 WRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRRF 492
W+PVVV+NGL AVRE LV++ +TSDRP + I H+GYG +S+GVILA YG WREQRRF
Sbjct: 78 WKPVVVVNGLKAVRELLVTYGEDTSDRPLMPIYNHIGYGHKSKGVILAPYGPEWREQRRF 137
Query: 493 SVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFARR 672
SVSTLR+FGLGKKSLE+WVT+EA LC AF +A PF+P+ LL+KAVSNVIASL +ARR
Sbjct: 138 SVSTLRDFGLGKKSLEQWVTEEAGHLCDAFTKEAEHPFNPSPLLSKAVSNVIASLIYARR 197
Query: 673 FEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMIDEL 852
FEY DP + +VL A+P+L HIPGL K FP+ +F+ +++++
Sbjct: 198 FEYEDPFFNRMLKTLKESLGEDTGFVGEVLNAIPMLLHIPGLPDKAFPKLNSFIALVNKM 257
Query: 853 ITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKPPRA---------------ASMMRTSAW- 984
+ EH T D AQPPRDLTDAFL E+++AKG P + A M+ TS
Sbjct: 258 LIEHDSTWDPAQPPRDLTDAFLAEVEKAKGNPESSFNDKNLRIVVIDLFMAGMVTTSTTL 317
Query: 985 -WWLTCSPLG*SPPRPRWPGLXXXXXXXXXXXDASNRKINEVIGHVRQPE 1131
W L L R +++I+EVIGHVR PE
Sbjct: 318 SWALLLMILHPDVQR------------------RVHQEIDEVIGHVRHPE 349
Score = 68.2 bits (165), Expect = 1e-11
Identities = 41/82 (50%), Positives = 48/82 (58%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*G 1106
E+ +G PESSFND+NLR+VV DLF AGM+ MILHPDVQRRV QE
Sbjct: 283 EKAKGN-PESSFNDKNLRIVVIDLFMAGMVTTSTTLSWALLLMILHPDVQRRVHQEIDEV 341
Query: 1107 DRARAATGKKDQALMPFTLAVL 1172
DQA MP+T AV+
Sbjct: 342 IGHVRHPEMADQARMPYTNAVI 363
>ref|NP_034138.3| cytochrome P450 2J6 [Mus musculus].
Length = 501
Score = 147 bits (371), Expect(2) = 3e-41
Identities = 93/269 (34%), Positives = 140/269 (52%), Gaps = 1/269 (0%)
Frame = +1
Query: 124 AMVIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSL 303
A V FLLL D ++R Y Q++F P LS L +++G++FSL
Sbjct: 24 AAVTFLLLADYF--KNRRPKNYPPGPWGLPFVGNIFQLDFGQPHLSIQPLVKKYGNIFSL 81
Query: 304 QQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQ 483
VV+ GL ++EAL +RP + E + G+I + G+ W+EQ
Sbjct: 82 NLGDITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERIS---NKNGLIFSS-GQIWKEQ 137
Query: 484 RRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTF 663
RRF++ TLRNFGLGKKSLEE + +EAS L A ++ G+PF+P+ +N AVSN+I S+TF
Sbjct: 138 RRFALMTLRNFGLGKKSLEERMQEEASHLVEAIREEEGKPFNPHFSINNAVSNIICSVTF 197
Query: 664 ARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGLCAKLFPRQKAFLVM 840
RF+Y+D R + Q+ P ++++IPG K+F + +
Sbjct: 198 GERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWIMKYIPGSHQKVFRNWEKLKLF 257
Query: 841 IDELITEHKMTRDLAQPPRDLTDAFLDEM 927
+ +I +H+ + PRD DAFL EM
Sbjct: 258 VSCMIDDHRKDWN-PDEPRDFIDAFLKEM 285
Score = 40.4 bits (93), Expect(2) = 3e-41
Identities = 26/73 (35%), Positives = 35/73 (47%)
Frame = +3
Query: 954 SSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARAATGK 1133
+SFN+ENL DLF AG M L+P+VQ +VQ E + A
Sbjct: 293 TSFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARL 352
Query: 1134 KDQALMPFTLAVL 1172
D+ MP+T AV+
Sbjct: 353 ADRESMPYTNAVI 365
>ref|NP_083255.1| cytochrome P450, family 2, subfamily j, polypeptide 9 [Mus musculus].
Length = 502
Score = 144 bits (362), Expect = 2e-34
Identities = 104/350 (29%), Positives = 159/350 (45%), Gaps = 8/350 (2%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQ 309
V FL L D + ++R Y ++ + P LS Q +++G+V SL
Sbjct: 26 VTFLFLADFL--KNRRPKNYPPGPMRLPFVGCLFHLDPKQPHLSLQQFVKKYGNVLSLDF 83
Query: 310 IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQRR 489
P VV+ G+ ++E H +RP + +HL G+I + + W+EQRR
Sbjct: 84 ANIPSVVITGMPLIKEIFTQMEHNFMNRPVTLLRKHLF---NKNGLIFSS-DQTWKEQRR 139
Query: 490 FSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFAR 669
F++ TLRNFGLGK+SLEE + +EA L A D+ G+PF P+ ++ AVSN+I S+TF
Sbjct: 140 FALMTLRNFGLGKRSLEERIQEEAHYLVEAIRDEGGQPFDPHFNISNAVSNIICSITFGE 199
Query: 670 RFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGLCAKLFPRQKAFLVMID 846
RF+Y+D + M Q+ P +L+++PG LF + + +
Sbjct: 200 RFDYHDSQFQEMLRLLDEAMCLESSMMCQLYNIFPRILQYLPGSHQTLFRNWRKLQLFVS 259
Query: 847 ELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKPPRAASMMRTSAWWWLTCSPLG----- 1011
+++ H+ D PRD DAFL EM + K + + L CS L
Sbjct: 260 DIVNNHRRDWD-PDEPRDFIDAFLTEMTKYPDKTTTSFNEEN------LICSTLDLFFAG 312
Query: 1012 --*SPPRPRWPGLXXXXXXXXXXXDASNRKINEVIGHVRQPEKRIRPSCP 1155
+ RW L + +I+ VIG RQP R S P
Sbjct: 313 TETTSTTLRWALL--CMALYPEVQEKMQAEIDRVIGQARQPNLADRDSMP 360
Database: RefSeq49_MP.fasta
Posted date: Oct 17, 2011 1:42 PM
Number of letters in database: 15,617,559
Number of sequences in database: 30,036
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 30036
Number of Hits to DB: 36,682,963
Number of extensions: 936898
Number of successful extensions: 3348
Number of sequences better than 1.0e-05: 61
Number of HSP's gapped: 3254
Number of HSP's successfully gapped: 97
Length of query: 390
Length of database: 15,617,559
Length adjustment: 103
Effective length of query: 287
Effective length of database: 12,523,851
Effective search space: 3594345237
Effective search space used: 3594345237
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)
Search to RefSeqSP_Rel49
BLASTX 2.2.24 [Aug-08-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20110601C-006978
(1172 letters)
Database: RefSeq49_SP.fasta
24,897 sequences; 11,343,932 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|XP_003355372.1| PREDICTED: vitamin D(3) 25-hydroxylase-like ... 482 e-136
Alignment gi|NP_999559.1| vitamin D(3) 25-hydroxylase [Sus scrofa]. 482 e-136
Alignment gi|XP_003355373.1| PREDICTED: vitamin D(3) 25-hydroxylase-like ... 356 2e-98
Alignment gi|XP_003360779.1| PREDICTED: cytochrome P450 2J2-like, partial... 135 7e-36
Alignment gi|XP_003128009.2| PREDICTED: cytochrome P450 2J2-like, partial... 132 1e-35
Alignment gi|XP_003359352.1| PREDICTED: LOW QUALITY PROTEIN: cytochrome P... 125 8e-34
Alignment gi|NP_999585.1| cytochrome P450 2C49 [Sus scrofa]. 124 3e-33
Alignment gi|XP_003129312.1| PREDICTED: cytochrome P450 2U1-like [Sus scr... 109 2e-30
Alignment gi|NP_999579.1| cytochrome P450 2C33 [Sus scrofa]. 115 5e-30
Alignment gi|XP_003128010.2| PREDICTED: cytochrome P450 2J2-like [Sus scr... 127 2e-29
>ref|XP_003355372.1| PREDICTED: vitamin D(3) 25-hydroxylase-like isoform 1 [Sus scrofa].
Length = 500
Score = 482 bits (1241), Expect = e-136
Identities = 259/339 (76%), Positives = 265/339 (78%), Gaps = 3/339 (0%)
Frame = +1
Query: 124 AMVIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSL 303
AMVIFLLLVDLMHRRSRWAPRY QVNFQDPRLSFIQLRRRFGDVFSL
Sbjct: 15 AMVIFLLLVDLMHRRSRWAPRYPPGPMPLPGLGNLLQVNFQDPRLSFIQLRRRFGDVFSL 74
Query: 304 QQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQ 483
QQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQ
Sbjct: 75 QQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQ 134
Query: 484 RRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTF 663
RRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTF
Sbjct: 135 RRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTF 194
Query: 664 ARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMI 843
ARRFEYNDPRM MRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMI
Sbjct: 195 ARRFEYNDPRMLKLLDLVLEGLKEEVGLMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMI 254
Query: 844 DELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKPPRAASMMRTSAWWWLTCSPLG*SPP 1023
DELITEHKMTRDLAQPPRDLTDAFLDEMKEAKG P + + L + L +
Sbjct: 255 DELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGNPESSFNDENLR----LVVADLFSAGM 310
Query: 1024 RPRWPGLXXXXXXXXXXXDASNR---KINEVIGHVRQPE 1131
L D R +I+EVIGHVRQPE
Sbjct: 311 ITTSTTLAWALLLMILHPDVQRRVQQEIDEVIGHVRQPE 349
Score = 84.7 bits (208), Expect = 9e-17
Identities = 50/75 (66%), Positives = 50/75 (66%)
Frame = +3
Query: 948 PESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARAAT 1127
PESSFNDENLRLVVADLFSAGMI MILHPDVQRRVQQE
Sbjct: 289 PESSFNDENLRLVVADLFSAGMITTSTTLAWALLLMILHPDVQRRVQQEIDEVIGHVRQP 348
Query: 1128 GKKDQALMPFTLAVL 1172
KDQALMPFTLAVL
Sbjct: 349 EIKDQALMPFTLAVL 363
>ref|NP_999559.1| vitamin D(3) 25-hydroxylase [Sus scrofa].
Length = 500
Score = 482 bits (1240), Expect = e-136
Identities = 262/353 (74%), Positives = 267/353 (75%), Gaps = 17/353 (4%)
Frame = +1
Query: 124 AMVIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSL 303
AMVIFLLLVDLMHRRSRWAPRY QVNFQDPRLSFIQLRRRFGDVFSL
Sbjct: 15 AMVIFLLLVDLMHRRSRWAPRYPPGPMPLPGLGNLLQVNFQDPRLSFIQLRRRFGDVFSL 74
Query: 304 QQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQ 483
QQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQ
Sbjct: 75 QQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQ 134
Query: 484 RRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTF 663
RRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTF
Sbjct: 135 RRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTF 194
Query: 664 ARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMI 843
ARRFEYNDPRM MRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMI
Sbjct: 195 ARRFEYNDPRMLKLLDLVLEGLKEEVGLMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMI 254
Query: 844 DELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKPPR---------------AASMMRTS 978
DELITEHKMTRDLAQPPRDLTDAFLDEMKEAKG P +A M+ TS
Sbjct: 255 DELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGNPESSFNDENLRLVVAHLFSAGMITTS 314
Query: 979 AW--WWLTCSPLG*SPPRPRWPGLXXXXXXXXXXXDASNRKINEVIGHVRQPE 1131
W L L R ++I+EVIGHVRQPE
Sbjct: 315 TTLAWALLLMILHPDVQR------------------RVQQEIDEVIGHVRQPE 349
Score = 82.0 bits (201), Expect = 6e-16
Identities = 49/75 (65%), Positives = 49/75 (65%)
Frame = +3
Query: 948 PESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARAAT 1127
PESSFNDENLRLVVA LFSAGMI MILHPDVQRRVQQE
Sbjct: 289 PESSFNDENLRLVVAHLFSAGMITTSTTLAWALLLMILHPDVQRRVQQEIDEVIGHVRQP 348
Query: 1128 GKKDQALMPFTLAVL 1172
KDQALMPFTLAVL
Sbjct: 349 EIKDQALMPFTLAVL 363
>ref|XP_003355373.1| PREDICTED: vitamin D(3) 25-hydroxylase-like isoform 2 [Sus scrofa].
Length = 449
Score = 356 bits (913), Expect = 2e-98
Identities = 208/339 (61%), Positives = 214/339 (63%), Gaps = 3/339 (0%)
Frame = +1
Query: 124 AMVIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSL 303
AMVIFLLLVDLMHRRSRWAPRY QVNFQDPRLSFIQLRRRFGDVFSL
Sbjct: 15 AMVIFLLLVDLMHRRSRWAPRYPPGPMPLPGLGNLLQVNFQDPRLSFIQLRRRFGDVFSL 74
Query: 304 QQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQ 483
QQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSE
Sbjct: 75 QQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSE-------------- 120
Query: 484 RRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTF 663
GRPFSPNNLLNKAVSNVIASLTF
Sbjct: 121 -------------------------------------GRPFSPNNLLNKAVSNVIASLTF 143
Query: 664 ARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMI 843
ARRFEYNDPRM MRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMI
Sbjct: 144 ARRFEYNDPRMLKLLDLVLEGLKEEVGLMRQVLEAMPVLRHIPGLCAKLFPRQKAFLVMI 203
Query: 844 DELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKPPRAASMMRTSAWWWLTCSPLG*SPP 1023
DELITEHKMTRDLAQPPRDLTDAFLDEMKEAKG P + + L + L +
Sbjct: 204 DELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGNPESSFNDENLR----LVVADLFSAGM 259
Query: 1024 RPRWPGLXXXXXXXXXXXDASNR---KINEVIGHVRQPE 1131
L D R +I+EVIGHVRQPE
Sbjct: 260 ITTSTTLAWALLLMILHPDVQRRVQQEIDEVIGHVRQPE 298
Score = 84.7 bits (208), Expect = 9e-17
Identities = 50/75 (66%), Positives = 50/75 (66%)
Frame = +3
Query: 948 PESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARAAT 1127
PESSFNDENLRLVVADLFSAGMI MILHPDVQRRVQQE
Sbjct: 238 PESSFNDENLRLVVADLFSAGMITTSTTLAWALLLMILHPDVQRRVQQEIDEVIGHVRQP 297
Query: 1128 GKKDQALMPFTLAVL 1172
KDQALMPFTLAVL
Sbjct: 298 EIKDQALMPFTLAVL 312
>ref|XP_003360779.1| PREDICTED: cytochrome P450 2J2-like, partial [Sus scrofa].
Length = 363
Score = 135 bits (340), Expect(2) = 7e-36
Identities = 78/237 (32%), Positives = 135/237 (56%), Gaps = 1/237 (0%)
Frame = +1
Query: 235 VNFQDPRLSFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILE 414
++F+ LS + +++G++FSL VV+ GL ++E LV + + ++RP + I +
Sbjct: 29 LDFEKAHLSLQRFVKKYGNIFSLDLCALSAVVVTGLPLIKEVLVHQNQKFANRPILPIQD 88
Query: 415 HLGYGPRSEGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQA 594
+ +++GV+ + G+ W+EQRRF+++TLRNFGLGKKSLEE + +EA L A ++
Sbjct: 89 RVF---KNKGVVTSS-GQVWKEQRRFTLTTLRNFGLGKKSLEERIQEEAQYLTQAIGEEN 144
Query: 595 GRPFSPNNLLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP 774
G+PF+P ++ AVSN+I S+TF +RF+Y D + Q+ P
Sbjct: 145 GQPFNPQFKISNAVSNIICSITFGKRFDYQDDQFQELLRLLREVTHLQTLLWCQLFNVFP 204
Query: 775 -VLRHIPGLCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAKG 942
+++ +PG LF + + I +I H+ + A+ RD DA+L E+++ KG
Sbjct: 205 RIMKFLPGPHQTLFSDWEKLEMFIARVIENHRRDWNPAE-ARDFIDAYLQEIEKNKG 260
Score = 33.9 bits (76), Expect(2) = 7e-36
Identities = 20/56 (35%), Positives = 27/56 (48%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQE 1094
E+ +G SSF++ENL DL AG M LHP++Q +VQ E
Sbjct: 256 EKNKGNAT-SSFHEENLICSTLDLLFAGTDTTLITLRWGLLYMALHPEIQEKVQAE 310
>ref|XP_003128009.2| PREDICTED: cytochrome P450 2J2-like, partial [Sus scrofa].
Length = 432
Score = 132 bits (332), Expect(2) = 1e-35
Identities = 77/223 (34%), Positives = 127/223 (56%), Gaps = 1/223 (0%)
Frame = +1
Query: 277 RRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILA 456
+++G+VFSL VV+ GL ++EA V S+RP V I + + + +GV+++
Sbjct: 3 KKYGNVFSLDFGALSSVVITGLPFIKEAFVHQDKNFSNRPIVPIQQRVF---KDKGVVMS 59
Query: 457 RYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAV 636
G+ W+EQRRF+++TLRNFGLGKKSLEE + +EA L A ++ G+PF+P+ +N AV
Sbjct: 60 N-GQVWKEQRRFALTTLRNFGLGKKSLEERIQEEAQYLIQAIGEENGQPFNPHFKINNAV 118
Query: 637 SNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGLCAKLF 813
SN+I S+TF RF+Y D + Q+ +P +++ +PG LF
Sbjct: 119 SNIICSITFGERFDYQDNQFQELLKLLDEVMCLQTSVWCQIYNIIPWIMKFLPGPHQTLF 178
Query: 814 PRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAKG 942
+ + + +I H+ + A+ RD +A+L E+++ KG
Sbjct: 179 SNWEKLKMFVAHVIENHRRDWNPAE-ARDFIEAYLQEIEKHKG 220
Score = 36.2 bits (82), Expect(2) = 1e-35
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Frame = +3
Query: 927 ERGQGETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQE--NQ 1100
E+ +G+ SSF +ENL DLF AG M L+P++Q +VQ E
Sbjct: 216 EKHKGDAT-SSFQEENLICSTLDLFVAGTETTSTTLRWGLLYMALYPEIQEKVQAEIDRV 274
Query: 1101 *GDRARAATGKKDQALMPFTLAVL 1172
G + +T ++ MP+T AV+
Sbjct: 275 LGQLQQPSTAARES--MPYTNAVI 296
>ref|XP_003359352.1| PREDICTED: LOW QUALITY PROTEIN: cytochrome P450 2C18 [Sus scrofa].
Length = 490
Score = 125 bits (314), Expect(2) = 8e-34
Identities = 83/237 (35%), Positives = 118/237 (49%), Gaps = 1/237 (0%)
Frame = +1
Query: 232 QVNFQDPRLSFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFIL 411
Q+N +D S L + +G VF++ +P VVL+G A++EAL+ E S R + +
Sbjct: 44 QLNVKDISKSLSNLSKVYGPVFTVYLGLKPAVVLHGYEAMKEALIDGGEEFSGRGHLPMA 103
Query: 412 EHLGYGPRSEGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQ 591
E + G G+I + GK W+E RRFS+ TLRNFG+GK+S+EE V +EA CL
Sbjct: 104 ERVNKG---HGIIFSS-GKRWKEIRRFSLMTLRNFGMGKRSIEERVQEEARCLVEELRKT 159
Query: 592 AGRPFSPNNLLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAM 771
P+ P LL A VI S+ F RF+Y DP QV
Sbjct: 160 NASPWDPTFLLGCAPCKVICSIIFRNRFDYTDPNFLTLLEKLNENFRILSSPWIQVCNNF 219
Query: 772 PVL-RHIPGLCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAK 939
P L ++PG K+F I E + EH+ + D+ PRD D FL +M++ K
Sbjct: 220 PALIDYLPGSHNKVFKNSAYVKSYILEKVKEHQASLDV-NDPRDFIDCFLIKMEQEK 275
Score = 37.0 bits (84), Expect(2) = 8e-34
Identities = 22/72 (30%), Positives = 35/72 (48%)
Frame = +3
Query: 957 SFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARAATGKK 1136
+F ENL ++DLF AG ++ HPDV +VQ+E + +
Sbjct: 281 AFTFENLIATISDLFGAGTETTSTTLRYGLLLLLKHPDVTAKVQKEIDSVIERHRSPCMQ 340
Query: 1137 DQALMPFTLAVL 1172
D++ MP+T AV+
Sbjct: 341 DRSRMPYTDAVV 352
>ref|NP_999585.1| cytochrome P450 2C49 [Sus scrofa].
Length = 490
Score = 124 bits (310), Expect(2) = 3e-33
Identities = 83/237 (35%), Positives = 117/237 (49%), Gaps = 1/237 (0%)
Frame = +1
Query: 232 QVNFQDPRLSFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFIL 411
Q++ +D S L + +G VF++ +P VVL+G AV+EAL+ E S R +
Sbjct: 44 QLDVKDISKSLSNLSKVYGPVFTVYFGLKPAVVLHGYEAVKEALIDGGEEFSGRGHFPMA 103
Query: 412 EHLGYGPRSEGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQ 591
E + G G+I + GK W+E RRFS+ TLRNFG+GK+S+EE V +EA CL
Sbjct: 104 ERVNKG---HGIIFSS-GKRWKETRRFSLMTLRNFGMGKRSIEERVQEEARCLVEELRKT 159
Query: 592 AGRPFSPNNLLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAM 771
P P LL A NVI S+ F RF+Y DP QV
Sbjct: 160 NASPCDPTFLLGCAPCNVICSIIFHNRFDYTDPNFLTLLEKLNENFRILSSPWMQVCNNF 219
Query: 772 PVL-RHIPGLCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAK 939
P L ++PG K+ I E + EH+ + D+ + PRD D FL +M++ K
Sbjct: 220 PALIDYLPGSHNKVLKNSAYVKSYILEKVKEHQASLDV-KDPRDFIDCFLIKMEQEK 275
Score = 36.6 bits (83), Expect(2) = 3e-33
Identities = 22/72 (30%), Positives = 34/72 (47%)
Frame = +3
Query: 957 SFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARAATGKK 1136
+F ENL + DLF AG ++ HPDV +VQ+E + +
Sbjct: 281 AFTFENLIATITDLFGAGTETTSTTLRYGLLLLLKHPDVTAKVQKEIDSVIERHRSPCMQ 340
Query: 1137 DQALMPFTLAVL 1172
D++ MP+T AV+
Sbjct: 341 DRSRMPYTDAVV 352
>ref|XP_003129312.1| PREDICTED: cytochrome P450 2U1-like [Sus scrofa].
Length = 543
Score = 109 bits (273), Expect(2) = 2e-30
Identities = 73/230 (31%), Positives = 117/230 (50%), Gaps = 1/230 (0%)
Frame = +1
Query: 253 RLSFIQLRRRFGDVFSLQQIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGP 432
+L +L +G+++S VVVLN +VREALV + SDRP + + L G
Sbjct: 104 QLLLAELAHVYGNIYSFFIGHYLVVVLNDFHSVREALVQQAEVFSDRPRMPLSYILTKG- 162
Query: 433 RSEGVILARYGKAWREQRRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSP 612
+G++ A YG WR+QR+FS STLR+FGLGK SLE + +E + PF+P
Sbjct: 163 --KGIVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFRFVKEEMQKHGEDPFNP 220
Query: 613 NNLLNKAVSNVIASLTFARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMPVLRHIP 792
++N AVSN+I SL F +RF+Y + ++ L ++P
Sbjct: 221 FPIVNNAVSNIICSLCFGQRFDYTNSEFKKMLNFMSRALEICLNTQLLLVNICSWLYYLP 280
Query: 793 -GLCAKLFPRQKAFLVMIDELITEHKMTRDLAQPPRDLTDAFLDEMKEAK 939
G +L +K + ++I +H+ + D+A P+D D +L ++E +
Sbjct: 281 FGPFKELRQIEKDITTFLKKIIKDHRESLDVAN-PQDFIDMYLLHVEEER 329
Score = 41.6 bits (96), Expect(2) = 2e-30
Identities = 26/73 (35%), Positives = 37/73 (50%)
Frame = +3
Query: 954 SSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARAATGK 1133
SSF+++ L ++ DLF AG M L+PDVQ +V +E + A A
Sbjct: 335 SSFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGADRAPSL 394
Query: 1134 KDQALMPFTLAVL 1172
D+A MP+T A L
Sbjct: 395 TDKAQMPYTEATL 407
>ref|NP_999579.1| cytochrome P450 2C33 [Sus scrofa].
Length = 494
Score = 115 bits (289), Expect(2) = 5e-30
Identities = 84/276 (30%), Positives = 131/276 (47%), Gaps = 3/276 (1%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPRYXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQQ 309
++FL + H+R R P Q+N +D S +L +++G V ++
Sbjct: 18 LVFLSVWKKNHKRRRLPP----GPTPLPIIGNLMQLNLKDIPASLSKLAKQYGPVCTVYF 73
Query: 310 IWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHL--GYGPRSEGVILARYGKAWREQ 483
+P VVL+G AV+EAL+ E R + I++ GYG ++ G+ W++
Sbjct: 74 GSQPAVVLHGYEAVKEALIDQGDEFLGRGIIPIIDDTQGGYG------LVFSNGERWKQI 127
Query: 484 RRFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTF 663
RRFS+ TLRNFG+GK+SLEE V +EA L +PF P +L+ A NVI S+ F
Sbjct: 128 RRFSLMTLRNFGMGKRSLEERVQEEAQFLVEELRKTEAQPFDPTFILSCAPCNVICSILF 187
Query: 664 ARRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGLCAKLFPRQKAFLVM 840
RF Y++ Q+ P +++H+PG R K
Sbjct: 188 NDRFHYDNETFLSLMNLLNANFRQISSPWIQIYNLWPQIIKHLPGEHRAFSKRLKDCRSF 247
Query: 841 IDELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKP 948
I E + EH+ + +L P+D D FL +M++ K P
Sbjct: 248 ILEKVKEHQKSPNL-NNPQDYIDCFLSKMEQEKQNP 282
Score = 33.9 bits (76), Expect(2) = 5e-30
Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Frame = +3
Query: 942 ETPESSFNDENLRLVVADLFSAGMIXXXXXXXXXXXXMILHPDVQRRVQQENQ*GDRARA 1121
+ P+S F+ ENL ++LF+AG ++ HP+VQ +V +E DR
Sbjct: 280 QNPDSEFHLENLINSGSNLFAAGTETTTSTLRYGLLLLMKHPEVQAKVHEEI---DRVIG 336
Query: 1122 ATGK---KDQALMPFTLAVL 1172
+ + +D+ +P+T AVL
Sbjct: 337 RSQRPCMQDKMKLPYTEAVL 356
>ref|XP_003128010.2| PREDICTED: cytochrome P450 2J2-like [Sus scrofa].
Length = 497
Score = 127 bits (318), Expect = 2e-29
Identities = 103/351 (29%), Positives = 161/351 (45%), Gaps = 9/351 (2%)
Frame = +1
Query: 130 VIFLLLVDLMHRRSRWAPR-YXXXXXXXXXXXXXXQVNFQDPRLSFIQLRRRFGDVFSLQ 306
V FL + D++ RW P+ Y ++F+ LS + +++G+V SL
Sbjct: 26 VAFLFVADIL---KRWRPKNYPPGPLRLPFVGNFLHLDFEQWHLSLQRFVKKYGNVLSLD 82
Query: 307 QIWRPVVVLNGLAAVREALVSHSHETSDRPPVFILEHLGYGPRSEGVILARYGKAWREQR 486
VV+ GL ++EALV +RP +L + G+I++ G+ W+EQR
Sbjct: 83 LGAFSSVVITGLPLIKEALVHQDQNFVNRPI-----NLNQVFQKNGLIMSN-GQVWKEQR 136
Query: 487 RFSVSTLRNFGLGKKSLEEWVTQEASCLCAAFADQAGRPFSPNNLLNKAVSNVIASLTFA 666
RF+++TLRNFGLGKKSLEE + +EA L A ++ G F P+ +N AVSN+I S+TF
Sbjct: 137 RFALTTLRNFGLGKKSLEERIQEEAQYLIQAVREENGDLFDPHFKINNAVSNIICSITFG 196
Query: 667 RRFEYNDPRMXXXXXXXXXXXXXXXXXMRQVLEAMP-VLRHIPGLCAKLFPRQKAFLVMI 843
RF+Y D + Q+ P +++ +PG +F ++ + I
Sbjct: 197 ERFDYQDDQFQELLRLLDEVTCLPKSVRVQLFNVFPRIMKLLPGPHQIIFSNREKLRMFI 256
Query: 844 DELITEHKMTRDLAQPPRDLTDAFLDEMKEAKGKPPRAASMMRTSAWWWLTCSPLG---- 1011
+I H+ + A+ RD DA+L E++ KG P + L CS L
Sbjct: 257 ARVIENHRRDWNPAE-ARDFIDAYLREIE--KGSSPSVFNEEN------LICSTLDLFFA 307
Query: 1012 ---*SPPRPRWPGLXXXXXXXXXXXDASNRKINEVIGHVRQPEKRIRPSCP 1155
+ RW L A +I+ V+G +QP R S P
Sbjct: 308 GTETTSTTLRWGLLYMALYPEVQEVQA---EIDRVLGQSQQPSTAARESMP 355
Database: RefSeq49_SP.fasta
Posted date: Oct 17, 2011 1:42 PM
Number of letters in database: 11,343,932
Number of sequences in database: 24,897
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 24897
Number of Hits to DB: 27,544,273
Number of extensions: 725176
Number of successful extensions: 2659
Number of sequences better than 1.0e-05: 26
Number of HSP's gapped: 2617
Number of HSP's successfully gapped: 43
Length of query: 390
Length of database: 11,343,932
Length adjustment: 101
Effective length of query: 289
Effective length of database: 8,829,335
Effective search space: 2551677815
Effective search space used: 2551677815
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 34 (17.7 bits)
Search to Sscrofa10_2
BLASTN 2.2.24 [Aug-08-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 20110601C-006978
(1172 letters)
Database: Sscrofa_10.2.fasta
4582 sequences; 2,808,509,378 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Sscrofa_Chr05 496 e-137
>Sscrofa_Chr05
|| Length = 111506441
Score = 496 bits (250), Expect = e-137
Identities = 256/258 (99%)
Strand = Plus / Minus
Query: 13 agagtgctctgcatggcctggtcttaggtgcttggtgcggtgaggagcccagtgtgcact 72
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 3815072 agagtgctctgcatggcctggtcttaggtgcttggtgcggtgaggagcccagtgtgcact 3815013
Query: 73 gaggcagccatgggtctgctgactggggatttactggggatcctggccttggccatggtc 132
|||||||||||||||||||||||||||| |||||||||||||||||||||||||||||||
Sbjct: 3815012 gaggcagccatgggtctgctgactgggggtttactggggatcctggccttggccatggtc 3814953
Query: 133 atcttcctgctcctggtggacttgatgcaccggcgctcacgctgggctccacgctaccca 192
|||||||||||||| |||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 3814952 atcttcctgctcctagtggacttgatgcaccggcgctcacgctgggctccacgctaccca 3814893
Query: 193 ccgggccccatgccactgcctgggctgggtaacctgctacaagtgaacttccaagaccca 252
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 3814892 ccgggccccatgccactgcctgggctgggtaacctgctacaagtgaacttccaagaccca 3814833
Query: 253 cgtctcagctttatccag 270
||||||||||||||||||
Sbjct: 3814832 cgtctcagctttatccag 3814815
Score = 333 bits (168), Expect = 1e-88
Identities = 171/172 (99%)
Strand = Plus / Minus
Query: 595 ggacgcccctttagccctaacaaccttctgaataaagcggtgagcaacgtgatcgcctcc 654
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 3812814 ggacgcccctttagccctaacaaccttctgaataaagcggtgagcaacgtgatcgcctcc 3812755
Query: 655 ctcaccttcgcgcgccgcttcgagtacaacgaccctcgcatgctcaagcttctggaccta 714
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 3812754 ctcaccttcgcgcgccgcttcgagtacaacgaccctcgcatgctcaagcttctggaccta 3812695
Query: 715 gtgttggaaggactgaaggaggaagtgggcctcatgcgccaggtgctggaag 766
|||||||||||||||||||||||||||||||||||||||||||||| |||||
Sbjct: 3812694 gtgttggaaggactgaaggaggaagtgggcctcatgcgccaggtgcgggaag 3812643
Score = 333 bits (168), Expect = 1e-88
Identities = 174/176 (98%)
Strand = Plus / Minus
Query: 268 cagctgcggcgccgctttggggatgtattcagcctgcagcagatctggaggcccgtggtc 327
||||||||||||||||| ||||||||||||||||| ||||||||||||||||||||||||
Sbjct: 3813842 cagctgcggcgccgcttcggggatgtattcagcctacagcagatctggaggcccgtggtc 3813783
Query: 328 gtgctcaatgggctggcggctgtgcgggaggcgctggtgtcccacagccatgaaacctcc 387
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 3813782 gtgctcaatgggctggcggctgtgcgggaggcgctggtgtcccacagccatgaaacctcc 3813723
Query: 388 gaccgcccacctgtgttcatcttagagcacctgggttacgggccgcgctccgaagg 443
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 3813722 gaccgcccacctgtgttcatcttagagcacctgggttacgggccgcgctccgaagg 3813667
Score = 317 bits (160), Expect = 8e-84
Identities = 174/181 (96%)
Strand = Plus / Minus
Query: 754 caggtgctggaagcaatgccggttctcaggcatatcccggggctgtgtgccaagctcttc 813
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 3812198 caggtgctggaagcaatgccggttctcaggcatatcccggggctgtgtgccaagctcttc 3812139
Query: 814 ccaaggcagaaggccttcttggtcatgatagatgagctgatcacagagcacaagatgacc 873
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 3812138 ccaaggcagaaggccttcttggtcatgatagatgagctgatcacagagcacaagatgacc 3812079
Query: 874 cgggacctggcccagnnnnnnngagacttgacggatgccttcctggacgaaatgaaagag 933
||||||||||||||| ||||||||||||||||||||||||||||||||||||||
Sbjct: 3812078 cgggacctggcccagcccccccgagacttgacggatgccttcctggacgaaatgaaagag 3812019
Query: 934 g 934
|
Sbjct: 3812018 g 3812018
Score = 301 bits (152), Expect = 5e-79
Identities = 155/156 (99%)
Strand = Plus / Minus
Query: 441 aggagtgatcctggcgcgctacgggaaagcgtggcgcgagcagcggcgcttctcggtgtc 500
||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||
Sbjct: 3813062 aggagtgatcctggcgcgctatgggaaagcgtggcgcgagcagcggcgcttctcggtgtc 3813003
Query: 501 caccttgcgcaactttggcctgggcaagaagtcgttggaggagtgggtgacccaagaggc 560
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 3813002 caccttgcgcaactttggcctgggcaagaagtcgttggaggagtgggtgacccaagaggc 3812943
Query: 561 ctcgtgcctttgtgccgccttcgccgaccaggctgg 596
||||||||||||||||||||||||||||||||||||
Sbjct: 3812942 ctcgtgcctttgtgccgccttcgccgaccaggctgg 3812907
Score = 254 bits (128), Expect = 9e-65
Identities = 143/147 (97%), Gaps = 2/147 (1%)
Strand = Plus / Minus
Query: 932 aggccaaggggaaacccccgagagcagcttcaatgatgagaacctccgcctggtggtggc 991
||||||||||||| |||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 3811850 aggccaaggggaa--ccccgagagcagcttcaatgatgagaacctccgcctggtggtggc 3811793
Query: 992 tgacctgttctccgctgggatgatcaccacctcgaccacgctggcctgggctctcctcct 1051
|||||||||||| || ||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 3811792 tgacctgttctctgccgggatgatcaccacctcgaccacgctggcctgggctctcctcct 3811733
Query: 1052 catgatcctgcacccagacgtgcagcg 1078
|||||||||||||||||||||||||||
Sbjct: 3811732 catgatcctgcacccagacgtgcagcg 3811706
Score = 135 bits (68), Expect = 6e-29
Identities = 91/96 (94%), Gaps = 2/96 (2%)
Strand = Plus / Minus
Query: 1078 gacgcgtccaacaggaaaatcaatgaggtgatagggcacgtgcggcaaccggaaa-aaag 1136
|||||||||||||||||| || |||||||||||||||||| |||||||||||| | ||||
Sbjct: 3811486 gacgcgtccaacaggaaa-tcgatgaggtgatagggcacgcgcggcaaccggagataaag 3811428
Query: 1137 gatcaggccctcatgcccttcaccttggccgtgctc 1172
||||||||||||||||||||||||||||||||||||
Sbjct: 3811427 gatcaggccctcatgcccttcaccttggccgtgctc 3811392
Database: Sscrofa_10.2.fasta
Posted date: Nov 16, 2011 10:34 AM
Number of letters in database: 2,808,509,378
Number of sequences in database: 4582
Lambda K H
1.37 0.711 1.31
Gapped
Lambda K H
1.37 0.711 1.31
Matrix: blastn matrix:1 -3
Gap Penalties: Existence: 5, Extension: 2
Number of Sequences: 4582
Number of Hits to DB: 26,923,142
Number of extensions: 135
Number of successful extensions: 135
Number of sequences better than 1.0e-05: 1
Number of HSP's gapped: 132
Number of HSP's successfully gapped: 7
Length of query: 1172
Length of database: 2,808,509,378
Length adjustment: 21
Effective length of query: 1151
Effective length of database: 2,808,413,156
Effective search space: 3232483542556
Effective search space used: 3232483542556
X1: 11 (21.8 bits)
X2: 15 (29.7 bits)
X3: 50 (99.1 bits)
S1: 18 (36.2 bits)
S2: 30 (60.0 bits)