Animal-Genome cDNA 20110601C-007014

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007014
         (1337 letters)

Database: RefSeq49_BP.fasta 
           33,088 sequences; 17,681,374 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_776955.2| cytochrome P450 2E1 [Bos taurus].                    612   e-175
Alignment   gi|NP_001069519.1| cytochrome P450, family 2, subfamily C, poly...   422   e-118
Alignment   gi|XP_002698440.1| PREDICTED: cytochrome P450, family 2, subfam...   413   e-115
Alignment   gi|XP_002698439.1| PREDICTED: cytochrome P450, family 2, subfam...   411   e-115
Alignment   gi|XP_612374.2| PREDICTED: cytochrome P450, family 2, subfamily...   411   e-115
Alignment   gi|NP_001103262.1| cytochrome P450, family 2, subfamily C, poly...   408   e-114
Alignment   gi|NP_001069895.1| cytochrome P450, family 2, subfamily C, poly...   407   e-113
Alignment   gi|XP_002698442.1| PREDICTED: cytochrome P450 family 2 subfamil...   406   e-113
Alignment   gi|XP_581757.3| PREDICTED: cytochrome P450 family 2 subfamily C...   406   e-113
Alignment   gi|XP_002698445.1| PREDICTED: cytochrome P450, family 2, subfam...   395   e-110

>ref|NP_776955.2| cytochrome P450 2E1 [Bos taurus].
          Length = 495

 Score =  612 bits (1577), Expect = e-175
 Identities = 293/368 (79%), Positives = 326/368 (88%)
 Frame = +2

Query: 230  MTALGIXXXXXXXXXXXXXISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTML 409
            M ALGI             ISIWKHI+SSWKLPPGPFPLPI+GN+ QLD+KNIPKSFT L
Sbjct: 1    MAALGITVALLVWMATLLFISIWKHIYSSWKLPPGPFPLPIIGNLLQLDIKNIPKSFTRL 60

Query: 410  AERYGPVFTVYLGSRRIVVLHGYKAVKEVLLHYKNEFSGRGEIPTFQVHKDKGVIFNNGP 589
            AERYGPVFT+YLGS+R VV+HGYK VKEVLL YKNEFSGRGE P FQ+HK+ G+IFNNG 
Sbjct: 61   AERYGPVFTLYLGSQRAVVVHGYKPVKEVLLDYKNEFSGRGENPGFQMHKNNGIIFNNGS 120

Query: 590  TWRDTRRFSLTTLRDFGMGKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVI 769
            TWRDTRRFSLTTLRD GMGKQGNEQRIQREAHFLLE LRKT GQPFDPTF++G AP NVI
Sbjct: 121  TWRDTRRFSLTTLRDLGMGKQGNEQRIQREAHFLLEVLRKTQGQPFDPTFVVGFAPYNVI 180

Query: 770  SDILFRQHFDYNDKTCLRLMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNIS 949
            SDILF + FDY D+T LRLMS+FNENFYLLS+ WIQLYNNFS YL+YLPGSHRKL+KN+S
Sbjct: 181  SDILFHKRFDYKDQTSLRLMSLFNENFYLLSSPWIQLYNNFSDYLQYLPGSHRKLLKNVS 240

Query: 950  EIKDYALERVKDHRDSLEPSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAG 1129
            E+K YALERVKDH+ SLEPSCPR F DT+L+EM KE++S +P+YTL+NIAVTVAD+ FAG
Sbjct: 241  EVKSYALERVKDHQKSLEPSCPRGFLDTMLIEMAKERHSVDPMYTLENIAVTVADLLFAG 300

Query: 1130 TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRF 1309
            TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGP+RIPA+KDRLDMPYLDAVVHEIQRF
Sbjct: 301  TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPSRIPAVKDRLDMPYLDAVVHEIQRF 360

Query: 1310 IDLIPLHL 1333
            IDL+P +L
Sbjct: 361  IDLLPSNL 368


>ref|NP_001069519.1| cytochrome P450, family 2, subfamily C, polypeptide 18 [Bos taurus].
          Length = 490

 Score =  422 bits (1085), Expect = e-118
 Identities = 203/351 (57%), Positives = 262/351 (74%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+WK      KLPPGP PLPI+GNI QLD+KNI KS + L+  YGPVFTVY G R  VV
Sbjct: 17   LSLWKQSSGKGKLPPGPTPLPILGNILQLDVKNIGKSLSNLSNTYGPVFTVYFGLRPTVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+    EFSGRG IP  Q V+K  G+IF+NG  W++ RRFSL TLR+FGM
Sbjct: 77   LHGYEAVKEALIDQGEEFSGRGNIPMSQRVNKGYGIIFSNGKRWKEIRRFSLMTLRNFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R+Q EAH L+E LRKT+G P DPTF++GCAPCNVI  I+F+  FDY D+  L 
Sbjct: 137  GKRSIEDRVQEEAHCLVEELRKTNGSPCDPTFILGCAPCNVICSIIFQNRFDYTDQNFLN 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            L+  FNEN  + S+ W+Q+ N F   + Y PGSH KL KN + I+ Y LE+VK+H+ +L+
Sbjct: 197  LLDKFNENLQVASSPWMQVCNTFPILIDYFPGSHNKLFKNFAYIRSYVLEKVKEHQATLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRDF D  L++ME+EK++ E  +T +N+  +V+D+F AGTETTSTTLRYGLL+L+K+
Sbjct: 257  INNPRDFIDCFLIKMEQEKHNQEMEFTFENLIASVSDLFGAGTETTSTTLRYGLLMLLKH 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV  K+ EEIDRVIG +R P ++DR  MPY+DAVVHEIQR+IDL+P +LP
Sbjct: 317  PEVTAKVQEEIDRVIGRHRSPCMQDRSHMPYMDAVVHEIQRYIDLVPTNLP 367


>ref|XP_002698440.1| PREDICTED: cytochrome P450, family 2, subfamily C, polypeptide
            87-like isoform 2 [Bos taurus].
          Length = 490

 Score =  413 bits (1061), Expect = e-115
 Identities = 201/351 (57%), Positives = 258/351 (73%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            IS+WK      KLPPGP PLPI+GNI QLD+K+I KS + L++ YGPVFT+Y G   +VV
Sbjct: 17   ISLWKQSSGKGKLPPGPTPLPILGNILQLDVKDISKSVSNLSKVYGPVFTLYFGMNPLVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+    EFSGRG  P  Q   K  GVIF+NG  W++TRRFSL TLRDFGM
Sbjct: 77   LHGYEAVKEALIGLGEEFSGRGSCPVIQRASKGYGVIFSNGKIWKETRRFSLMTLRDFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R+Q+EA  L+E LRKT G P DPTF++GCAPCNVI  I+F+ HFDY D+  L 
Sbjct: 137  GKRSMEDRVQQEACCLVEELRKTDGLPCDPTFILGCAPCNVICSIIFQNHFDYKDQIFLD 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM   NEN  +L + WIQL ++F   + Y+PG H+K  +N + +K Y LE+ ++H+ SL+
Sbjct: 197  LMERLNENARILGSPWIQLCSSFPALIDYVPGKHKKFFENYACMKSYVLEKTREHQASLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRDF D  L +MEKEK++ E  YT++N+A TV D+F AGTETTSTTLRYGLL+L+K+
Sbjct: 257  MNNPRDFIDCFLTKMEKEKHNQELEYTVENLAHTVLDLFVAGTETTSTTLRYGLLLLLKH 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV  K+ EEID VIG +R P ++D+  MPY DAVVHEIQR+IDL+P +LP
Sbjct: 317  PEVTAKVQEEIDHVIGRHRSPCMQDKSHMPYTDAVVHEIQRYIDLVPTNLP 367


>ref|XP_002698439.1| PREDICTED: cytochrome P450, family 2, subfamily C, polypeptide
            87-like isoform 1 [Bos taurus].
          Length = 490

 Score =  411 bits (1057), Expect = e-115
 Identities = 200/351 (56%), Positives = 258/351 (73%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            IS+WK      KLPPGP PLPI+GNI QLD+K+I KS + L++ YGPVFT+Y G   +VV
Sbjct: 17   ISLWKQSSGKGKLPPGPTPLPILGNILQLDVKDISKSVSNLSKVYGPVFTLYFGMNPLVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+    EFSGRG  P  Q   K  GVIF+NG  W++TRRFSL TLRDFGM
Sbjct: 77   LHGYEAVKEALIGLGEEFSGRGSCPVIQRASKGYGVIFSNGKIWKETRRFSLMTLRDFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R+Q+EA  L+E LRKT G P DPTF++GCAPCNVI  I+F+ HFDY D+  L 
Sbjct: 137  GKRSMEDRVQQEACCLVEELRKTDGLPCDPTFILGCAPCNVICSIIFQNHFDYKDQIFLD 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM   NEN  +L + WIQL ++F   + Y+PG H+K  +N + +K Y LE+ ++H+ SL+
Sbjct: 197  LMERLNENARILGSPWIQLCSSFPALIDYVPGKHKKFFENYACMKSYVLEKTREHQASLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRDF D  L +ME+EK++ E  YT++N+A TV D+F AGTETTSTTLRYGLL+L+K+
Sbjct: 257  MNNPRDFIDCFLTKMEQEKHNQELEYTVENLAHTVLDLFVAGTETTSTTLRYGLLLLLKH 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV  K+ EEID VIG +R P ++D+  MPY DAVVHEIQR+IDL+P +LP
Sbjct: 317  PEVTAKVQEEIDHVIGRHRSPCMQDKSHMPYTDAVVHEIQRYIDLVPTNLP 367


>ref|XP_612374.2| PREDICTED: cytochrome P450, family 2, subfamily C, polypeptide
            87-like isoform 2 [Bos taurus].
          Length = 490

 Score =  411 bits (1057), Expect = e-115
 Identities = 200/351 (56%), Positives = 258/351 (73%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            IS+WK      KLPPGP PLPI+GNI QLD+K+I KS + L++ YGPVFT+Y G   +VV
Sbjct: 17   ISLWKQSSGKGKLPPGPTPLPILGNILQLDVKDISKSVSNLSKVYGPVFTLYFGMNPLVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+    EFSGRG  P  Q   K  GVIF+NG  W++TRRFSL TLRDFGM
Sbjct: 77   LHGYEAVKEALIGLGEEFSGRGSCPVIQRASKGYGVIFSNGKIWKETRRFSLMTLRDFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R+Q+EA  L+E LRKT G P DPTF++GCAPCNVI  I+F+ HFDY D+  L 
Sbjct: 137  GKRSMEDRVQQEACCLVEELRKTDGLPCDPTFILGCAPCNVICSIIFQNHFDYKDQIFLD 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM   NEN  +L + WIQL ++F   + Y+PG H+K  +N + +K Y LE+ ++H+ SL+
Sbjct: 197  LMERLNENARILGSPWIQLCSSFPALIDYVPGKHKKFFENYACMKSYVLEKTREHQASLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRDF D  L +ME+EK++ E  YT++N+A TV D+F AGTETTSTTLRYGLL+L+K+
Sbjct: 257  MNNPRDFIDCFLTKMEQEKHNQELEYTVENLAHTVLDLFVAGTETTSTTLRYGLLLLLKH 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV  K+ EEID VIG +R P ++D+  MPY DAVVHEIQR+IDL+P +LP
Sbjct: 317  PEVTAKVQEEIDHVIGRHRSPCMQDKSHMPYTDAVVHEIQRYIDLVPTNLP 367


>ref|NP_001103262.1| cytochrome P450, family 2, subfamily C, polypeptide 19 [Bos taurus].
          Length = 490

 Score =  408 bits (1048), Expect = e-114
 Identities = 192/349 (55%), Positives = 256/349 (73%), Gaps = 1/349 (0%)
 Frame = +2

Query: 293  IWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVVLH 472
            +W   H+  KLPPGP PLPIVGNI Q+++KN+ KS + LAE YGPVFT+Y G +  VVLH
Sbjct: 19   LWNQRHAKGKLPPGPTPLPIVGNILQINIKNVSKSISKLAEDYGPVFTLYFGMKPTVVLH 78

Query: 473  GYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGMGK 649
            GY+AVK+VL+    EFSGRG +P    +++  G++F+NG  W+ TRRFSL  LR+ GMGK
Sbjct: 79   GYEAVKQVLIDQSEEFSGRGSLPVADNINQGLGIVFSNGEIWKQTRRFSLMVLRNMGMGK 138

Query: 650  QGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLRLM 829
            +  E RIQ EA  L+EAL+KT+G P DPT L+ CAPCNVI  I+FR  F+YND+  L L+
Sbjct: 139  RTIEHRIQEEALCLVEALKKTNGSPCDPTLLLSCAPCNVICSIIFRNRFEYNDERLLTLI 198

Query: 830  SMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLEPS 1009
              FNEN  L+ST W++LYN F   L Y PGSH  + KN++E + + LE +K H++SL+ +
Sbjct: 199  KYFNENSRLVSTPWVELYNTFPSLLHYFPGSHNTIFKNMTEQRKFILEEIKKHQESLDLN 258

Query: 1010 CPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKYPE 1189
             P+DF D  L++MEKEK++    +T+DN+  TV D+F AGTETTS TLRYGLL+L+K+PE
Sbjct: 259  NPQDFIDYFLIKMEKEKHNKHSEFTMDNLITTVWDVFSAGTETTSLTLRYGLLLLLKHPE 318

Query: 1190 VEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            V  K+ EEIDRV+G NR P ++D+  MPY DAV+HEIQR+IDL+P  +P
Sbjct: 319  VTAKVQEEIDRVVGRNRSPCMQDKSCMPYTDAVLHEIQRYIDLVPSSMP 367


>ref|NP_001069895.1| cytochrome P450, family 2, subfamily C, polypeptide 87 [Bos taurus].
          Length = 492

 Score =  407 bits (1046), Expect = e-113
 Identities = 197/353 (55%), Positives = 260/353 (73%), Gaps = 3/353 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+WK      KLPPGP PLPI+GNIFQLD+KNI KS T L++ YGPVFTVY G +  VV
Sbjct: 17   LSLWKQSSGKGKLPPGPTPLPILGNIFQLDVKNISKSLTSLSKVYGPVFTVYFGMKPTVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQVH-KDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+    EFS RG  P  + + K  G++F+NG TW++TRRFSL TLR+FGM
Sbjct: 77   LHGYEAVKEALIDLGEEFSRRGSFPVIERNVKGHGIVFSNGKTWKETRRFSLMTLRNFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R+Q EA  L+E LRKT+G P DPTF++GCAPCNVI  I+F+  FDY D+T L 
Sbjct: 137  GKRSIEDRVQEEARCLVEELRKTNGLPCDPTFILGCAPCNVICSIIFQNRFDYKDQTFLN 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSH--RKLMKNISEIKDYALERVKDHRDS 997
            LM   NEN  +L + WIQ+ N F   L + P S+  +KL  N + +K+Y LE+ ++H+ S
Sbjct: 197  LMKTINENIKILGSPWIQVLNIFPVLLDFFPWSYSYKKLYTNTAYVKNYVLEKTREHQAS 256

Query: 998  LEPSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILM 1177
            L+ + PRDF D  L++ME+EK++ +  YT +N+ +TV+D+F AGTETTSTTLRYGLL+L+
Sbjct: 257  LDINNPRDFIDCFLIKMEQEKHNHQSEYTFENLTITVSDLFGAGTETTSTTLRYGLLLLL 316

Query: 1178 KYPEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            K+PEV  K+ EEIDRVIG +R P ++DR  MPY+DAV+HEIQR+IDL P  +P
Sbjct: 317  KHPEVTAKIQEEIDRVIGRHRSPCMQDRTHMPYMDAVLHEIQRYIDLAPTSVP 369


>ref|XP_002698442.1| PREDICTED: cytochrome P450 family 2 subfamily C polypeptide 18-like
            isoform 1 [Bos taurus].
          Length = 490

 Score =  406 bits (1044), Expect = e-113
 Identities = 197/351 (56%), Positives = 255/351 (72%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+WK      KLPPGP PLPI+GNI QLD+KNI KS T L++ YGPVFTVY G + IVV
Sbjct: 17   LSLWKQSSGKGKLPPGPTPLPILGNILQLDVKNISKSLTNLSKVYGPVFTVYFGMKPIVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+    EFSGRG  P  +  +   G++F+NG TW++ RRFSL TLR+FGM
Sbjct: 77   LHGYEAVKEALIDLGEEFSGRGMFPLAERANIVNGILFSNGKTWKEIRRFSLMTLRNFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R+Q EA  L+E LRKT+G P DPTF++GCAPCNVI  I+F+  FDY D   L 
Sbjct: 137  GKRSIEDRVQEEACCLVEELRKTNGLPCDPTFILGCAPCNVICSIIFQNRFDYKDPVFLD 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM   NE   +LS+ W+Q+ NNF     YLPGSH K++KN++ +K + LE+  +H+ SL+
Sbjct: 197  LMERLNEILRILSSPWVQVCNNFPALFDYLPGSHNKVLKNVANLKSFVLEKAMEHKASLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRD+ D  L+ ME+EK + +  +TL+N+  TV D+F AGTET STTLRYGLL+L+K+
Sbjct: 257  INNPRDYIDCFLIRMEQEKQNQQLEFTLENLTTTVFDLFGAGTETMSTTLRYGLLLLLKH 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV  K+ EEIDRVIG +R P ++DR  MPY DAVVHEIQR+IDL+P  LP
Sbjct: 317  PEVTAKVQEEIDRVIGRHRSPCMQDRSHMPYTDAVVHEIQRYIDLVPSSLP 367


>ref|XP_581757.3| PREDICTED: cytochrome P450 family 2 subfamily C polypeptide 18-like
            isoform 2 [Bos taurus].
          Length = 490

 Score =  406 bits (1044), Expect = e-113
 Identities = 197/351 (56%), Positives = 255/351 (72%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+WK      KLPPGP PLPI+GNI QLD+KNI KS T L++ YGPVFTVY G + IVV
Sbjct: 17   LSLWKQSSGKGKLPPGPTPLPILGNILQLDVKNISKSLTNLSKVYGPVFTVYFGMKPIVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+    EFSGRG  P  +  +   G++F+NG TW++ RRFSL TLR+FGM
Sbjct: 77   LHGYEAVKEALIDLGEEFSGRGMFPLAERANIVNGILFSNGKTWKEIRRFSLMTLRNFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R+Q EA  L+E LRKT+G P DPTF++GCAPCNVI  I+F+  FDY D   L 
Sbjct: 137  GKRSIEDRVQEEACCLVEELRKTNGLPCDPTFILGCAPCNVICSIIFQNRFDYKDPVFLD 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM   NE   +LS+ W+Q+ NNF     YLPGSH K++KN++ +K + LE+  +H+ SL+
Sbjct: 197  LMERLNEILRILSSPWVQVCNNFPALFDYLPGSHNKVLKNVANLKSFVLEKAMEHKASLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRD+ D  L+ ME+EK + +  +TL+N+  TV D+F AGTET STTLRYGLL+L+K+
Sbjct: 257  INNPRDYIDCFLIRMEQEKQNQQLEFTLENLTTTVFDLFGAGTETMSTTLRYGLLLLLKH 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV  K+ EEIDRVIG +R P ++DR  MPY DAVVHEIQR+IDL+P  LP
Sbjct: 317  PEVTAKVQEEIDRVIGRHRSPCMQDRSHMPYTDAVVHEIQRYIDLVPSSLP 367


>ref|XP_002698445.1| PREDICTED: cytochrome P450, family 2, subfamily C, polypeptide
            19-like isoform 2 [Bos taurus].
          Length = 490

 Score =  395 bits (1014), Expect = e-110
 Identities = 188/349 (53%), Positives = 257/349 (73%), Gaps = 1/349 (0%)
 Frame = +2

Query: 293  IWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVVLH 472
            +W   H+   LPPGP PLPIVGNI Q+++KN+ KS + LAE YGPVFT+Y G +  VVLH
Sbjct: 19   LWNQRHAKGTLPPGPTPLPIVGNILQINIKNVSKSISKLAEDYGPVFTLYFGMKPTVVLH 78

Query: 473  GYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGMGK 649
            GY+AVK+VL+    EFSGRG +P    +++  G+IF+NG  W+ TRRFSL  LR+ GMGK
Sbjct: 79   GYEAVKQVLIDQSEEFSGRGSLPVADNINQGLGIIFSNGEIWKQTRRFSLMVLRNMGMGK 138

Query: 650  QGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLRLM 829
            +  E RIQ EA  L+EAL+KT+G P DPTFL+  APCNVI  I+FR  F+Y+D++ L L 
Sbjct: 139  RTIEHRIQEEALCLVEALKKTNGCPCDPTFLLTYAPCNVICSIIFRNRFEYSDESFLTLA 198

Query: 830  SMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLEPS 1009
               +EN  + ST WI+LYN F   L YLPGSH  L KN++E + + LE++K+H++SL+ +
Sbjct: 199  KYIHENATIFSTPWIELYNAFPSLLHYLPGSHNTLFKNMTEQRKFILEKIKEHQESLDLN 258

Query: 1010 CPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKYPE 1189
             P+DF D  L++MEKEK++ +  +T+DN+  TV D+F AG ETTS +L+YGLL+L+K+PE
Sbjct: 259  NPQDFIDYFLIKMEKEKHNKQSEFTMDNLITTVWDVFTAGIETTSISLKYGLLLLLKHPE 318

Query: 1190 VEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            V  K+ EEI+RV+G NR P ++DR  MPY DAV+HEIQR+ID++P +LP
Sbjct: 319  VTAKVQEEINRVVGRNRSPCMQDRSRMPYTDAVIHEIQRYIDIVPNNLP 367


  Database: RefSeq49_BP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 17,681,374
  Number of sequences in database:  33,088
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33088
Number of Hits to DB: 44,228,326
Number of extensions: 1352988
Number of successful extensions: 4072
Number of sequences better than 1.0e-05: 67
Number of HSP's gapped: 3992
Number of HSP's successfully gapped: 77
Length of query: 445
Length of database: 17,681,374
Length adjustment: 105
Effective length of query: 340
Effective length of database: 14,207,134
Effective search space: 4830425560
Effective search space used: 4830425560
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007014
         (1337 letters)

Database: RefSeq49_CP.fasta 
           33,336 sequences; 18,874,504 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_001003339.1| cytochrome P450 2E1 [Canis lupus familiaris].     577   e-164
Alignment   gi|NP_001183973.1| cytochrome P450 2C21 [Canis lupus familiaris].    400   e-111
Alignment   gi|NP_001003334.1| cytochrome P450 2C41 [Canis lupus familiaris].    384   e-107
Alignment   gi|XP_541606.2| PREDICTED: similar to Cytochrome P450 2G1 (CYPI...   372   e-103
Alignment   gi|XP_855301.1| PREDICTED: similar to cytochrome P450, family 2...   355   5e-98
Alignment   gi|NP_001006653.1| cytochrome P450 2B11 [Canis lupus familiaris].    347   1e-95
Alignment   gi|NP_001032422.1| cytochrome P450 family 2 subfamily A polypep...   347   1e-95
Alignment   gi|NP_001041492.1| hypothetical protein LOC484493 [Canis lupus ...   345   4e-95
Alignment   gi|XP_855605.1| PREDICTED: cytochrome P450 2B11 [Canis familiar...   345   4e-95
Alignment   gi|XP_533661.2| PREDICTED: similar to cytochrome P450 monooxyge...   308   8e-84

>ref|NP_001003339.1| cytochrome P450 2E1 [Canis lupus familiaris].
          Length = 494

 Score =  577 bits (1486), Expect = e-164
 Identities = 270/369 (73%), Positives = 319/369 (86%)
 Frame = +2

Query: 230  MTALGIXXXXXXXXXXXXXISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTML 409
            M ALGI             ISIWK I+S WKLPPGPFPLPI+GNI Q+D+KN+PKS   L
Sbjct: 1    MAALGITVALLVWMATLMLISIWKQIYSRWKLPPGPFPLPIIGNILQVDIKNVPKSLAKL 60

Query: 410  AERYGPVFTVYLGSRRIVVLHGYKAVKEVLLHYKNEFSGRGEIPTFQVHKDKGVIFNNGP 589
            AE+YGPVFT+YLGS+R VVLHGYKAVKEVLL +KN+ SGRGE+  FQ HKD+G+ FNNGP
Sbjct: 61   AEQYGPVFTLYLGSQRTVVLHGYKAVKEVLLDHKNDLSGRGEVFAFQSHKDRGITFNNGP 120

Query: 590  TWRDTRRFSLTTLRDFGMGKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVI 769
             W+DTRR SL+TLRD+GMGK+GNE+RIQRE  FLLEALR T GQPFDPTFL+G AP NVI
Sbjct: 121  GWKDTRRLSLSTLRDYGMGKRGNEERIQREIPFLLEALRGTRGQPFDPTFLLGFAPFNVI 180

Query: 770  SDILFRQHFDYNDKTCLRLMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNIS 949
            +DILF +HFDY+D+T LR+  +FNENF+LLSTGW+QLYN F  YL YLPGSHRK+++N++
Sbjct: 181  ADILFHKHFDYSDQTGLRIQKLFNENFHLLSTGWLQLYNIFPSYLHYLPGSHRKVLRNVA 240

Query: 950  EIKDYALERVKDHRDSLEPSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAG 1129
            E+KDY+LERVK+H++SL+P+C RDFTD LL E++KE+Y  EP YTLDNIAVTVAD+FFAG
Sbjct: 241  ELKDYSLERVKEHQESLDPTCSRDFTDCLLQELQKERYGTEPWYTLDNIAVTVADLFFAG 300

Query: 1130 TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRF 1309
            TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGP+R+PAIKDRL+MPY+DAVVHEIQRF
Sbjct: 301  TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPSRVPAIKDRLEMPYMDAVVHEIQRF 360

Query: 1310 IDLIPLHLP 1336
            IDL+P +LP
Sbjct: 361  IDLLPSNLP 369


>ref|NP_001183973.1| cytochrome P450 2C21 [Canis lupus familiaris].
          Length = 490

 Score =  400 bits (1029), Expect = e-111
 Identities = 192/349 (55%), Positives = 253/349 (72%), Gaps = 1/349 (0%)
 Frame = +2

Query: 293  IWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVVLH 472
            +W    +  KLPPGP PLPI+GNI Q++ KN+ KS + LAE YGPVFTVY G +  VVL+
Sbjct: 19   LWNQNRAKGKLPPGPTPLPIIGNILQINTKNVSKSLSKLAENYGPVFTVYFGMKPTVVLY 78

Query: 473  GYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGMGK 649
            GY+AVKE L+    EFSGRG  P      +  G++F+NG  W+ TRRFSLT LR+ GMGK
Sbjct: 79   GYEAVKEALIDRSEEFSGRGHFPLLDWTIQGLGIVFSNGEKWKQTRRFSLTVLRNMGMGK 138

Query: 650  QGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLRLM 829
            +  E RIQ EA +L+EAL+KT+  P DPTFL+GCAPCNVI  I+F+  F+Y+DK  L L+
Sbjct: 139  KTVEDRIQEEALYLVEALKKTNASPCDPTFLLGCAPCNVICSIIFQNRFEYDDKDFLTLL 198

Query: 830  SMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLEPS 1009
              F+EN  + ST WIQLYN F   + YLPGSH  L KNI+    +  E++K+H +SL  S
Sbjct: 199  EYFHENLLISSTSWIQLYNAFPLLIHYLPGSHHVLFKNIANQFKFISEKIKEHEESLNFS 258

Query: 1010 CPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKYPE 1189
             PRDF D  L+++EKEK++ +  +T+DN+ +T+ D+F AGTETTSTTLRYGLL+L+K+P+
Sbjct: 259  NPRDFIDYFLIKIEKEKHNKQSEFTMDNLIITIWDVFSAGTETTSTTLRYGLLVLLKHPD 318

Query: 1190 VEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            V  K+ EEI RV+G +R P ++DR  MPY DAVVHEIQR+IDL+P +LP
Sbjct: 319  VTAKVQEEIHRVVGRHRSPCMQDRSCMPYTDAVVHEIQRYIDLVPNNLP 367


>ref|NP_001003334.1| cytochrome P450 2C41 [Canis lupus familiaris].
          Length = 489

 Score =  384 bits (987), Expect = e-107
 Identities = 187/351 (53%), Positives = 248/351 (70%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+WK      KLPPGP PLP +GNI QLD K+I KS + L++ YGPVFT+Y G +  VV
Sbjct: 17   LSLWKQSSRKGKLPPGPTPLPFIGNILQLD-KDINKSLSNLSKAYGPVFTLYFGMKPTVV 75

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY AVKE L+    EFS RG  P  + V    G+IF +G  W++ RRF+LTTLR+ GM
Sbjct: 76   LHGYDAVKETLIDLGEEFSARGRFPIAEKVSGGHGIIFTSGNRWKEMRRFALTTLRNLGM 135

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK   E R+Q EA +L+E LRKT+  P DPTF++GCA CNVI  I+F+  FDY D+T + 
Sbjct: 136  GKSDLESRVQEEACYLVEELRKTNALPCDPTFVLGCASCNVICSIIFQNRFDYTDQTLIG 195

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
             +   NENF +LS+ WIQ YN+F   L YLPGSH  + KN + IK Y LE++K+H++S +
Sbjct: 196  FLEKLNENFRILSSPWIQAYNSFPALLHYLPGSHNTIFKNFAFIKSYILEKIKEHQESFD 255

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRDF D  L++ME+EK++    +T +N+     D+F AGTETTSTTLRYGLL+L+K+
Sbjct: 256  VNNPRDFIDYFLIKMEQEKHNQPLEFTFENLKTIATDLFGAGTETTSTTLRYGLLLLLKH 315

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV  K+ EEIDRVIG ++ P ++DR  MPY +AV+HEIQR+IDL+P  LP
Sbjct: 316  PEVTVKVQEEIDRVIGRHQSPHMQDRSRMPYTNAVLHEIQRYIDLVPNSLP 366


>ref|XP_541606.2| PREDICTED: similar to Cytochrome P450 2G1 (CYPIIG1) (P450-OLF1)
            (Olfactive) [Canis familiaris].
          Length = 494

 Score =  372 bits (955), Expect = e-103
 Identities = 180/348 (51%), Positives = 242/348 (69%), Gaps = 1/348 (0%)
 Frame = +2

Query: 296  WKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVVLHG 475
            WK      KLPPGP P+P +GN+ Q+      +SF  L E+YGP+FTVY+G R +VVL G
Sbjct: 24   WKRNSKGGKLPPGPTPIPFLGNVLQVRTDATFQSFMKLREKYGPIFTVYMGPRPVVVLCG 83

Query: 476  YKAVKEVLLHYKNEFSGRGEIPTFQVH-KDKGVIFNNGPTWRDTRRFSLTTLRDFGMGKQ 652
            ++AVKE L+   +EFSGRGE+ + + + +  GV   NG  WR  RRFSLT LRDFGMGK+
Sbjct: 84   HEAVKEALVDRADEFSGRGELASIERNFQGHGVALANGERWRILRRFSLTILRDFGMGKR 143

Query: 653  GNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLRLMS 832
              E+RIQ EA FLLE LRKT G P +PTF +     NVIS ++F   FDY DK  L+L+ 
Sbjct: 144  SIEERIQEEAGFLLEELRKTKGSPIEPTFFLSRTVSNVISSVVFGSRFDYEDKQFLKLLQ 203

Query: 833  MFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLEPSC 1012
            M NE+F  +ST W QLY+ +SG ++YLPG H ++   I E+KD+   RVK +  SL+P  
Sbjct: 204  MINESFIEMSTPWAQLYDMYSGIMQYLPGRHNRIYYLIEELKDFIASRVKINEASLDPQN 263

Query: 1013 PRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKYPEV 1192
            PRDF D  L++M ++  +    + L N+ +T  ++FFAGTET S+TLRYGLL++MK+PEV
Sbjct: 264  PRDFIDCFLIKMHQDTNNPHTEFNLKNLVLTTLNLFFAGTETVSSTLRYGLLLMMKHPEV 323

Query: 1193 EEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            E K+HEEID+VIGP+RIP++ DR  MPY DAV+HEIQR  D++P+ +P
Sbjct: 324  EAKIHEEIDQVIGPHRIPSVDDRAKMPYTDAVIHEIQRLTDIVPMGVP 371


>ref|XP_855301.1| PREDICTED: similar to cytochrome P450, family 2, subfamily F,
            polypeptide 1 [Canis familiaris].
          Length = 582

 Score =  355 bits (911), Expect = 5e-98
 Identities = 171/380 (45%), Positives = 246/380 (64%), Gaps = 1/380 (0%)
 Frame = +2

Query: 200  PHIERSPEGAMTALGIXXXXXXXXXXXXXISIWKHIHSSWKLPPGPFPLPIVGNIFQLDL 379
            P I++ P  A T  G+             + +  +     +LPPGP PLP +GN+ QL  
Sbjct: 64   PKIQQIPAAAFTMDGVSTAILLGLLALAFLFLILNSRGKSQLPPGPRPLPFLGNLLQLRS 123

Query: 380  KNIPKSFTMLAERYGPVFTVYLGSRRIVVLHGYKAVKEVLLHYKNEFSGRGEIPTF-QVH 556
            +++  S T L++ YG V+TV+LG RR+VVL GY+AVKE L+    +FSGRG+ P F    
Sbjct: 124  QDMLTSLTKLSKEYGSVYTVHLGPRRVVVLSGYQAVKEALVDQGEDFSGRGDYPVFFNFT 183

Query: 557  KDKGVIFNNGPTWRDTRRFSLTTLRDFGMGKQGNEQRIQREAHFLLEALRKTHGQPFDPT 736
            K  G+ F+NG  W+  RRFS+  LR+FGMGK+  E+RI  E  FLL  LRKT G+PFDPT
Sbjct: 184  KGNGIAFSNGDRWKVLRRFSVQILRNFGMGKRSIEERILEEGSFLLAELRKTEGKPFDPT 243

Query: 737  FLIGCAPCNVISDILFRQHFDYNDKTCLRLMSMFNENFYLLSTGWIQLYNNFSGYLRYLP 916
            F++  +  N+I  ++F   FDY+D+  L ++ + N+NF ++S  W +LYN F   L ++P
Sbjct: 244  FVLSRSVSNIICSVIFGSRFDYDDERLLTIIRLINDNFQIMSGPWGELYNIFPSLLDWIP 303

Query: 917  GSHRKLMKNISEIKDYALERVKDHRDSLEPSCPRDFTDTLLMEMEKEKYSAEPIYTLDNI 1096
            G HR+L +N   +KD     V+DH+DSL+P CPRDF D  L +M +EK      + +D +
Sbjct: 304  GPHRRLFQNFGCMKDLIARSVRDHQDSLDPRCPRDFIDCFLNKMAQEKQDPHSHFHMDTL 363

Query: 1097 AVTVADMFFAGTETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPNRIPAIKDRLDMPY 1276
             +T  ++ F GTET  TTLR+  L+LMKYP+V+ ++ EEIDRV+G  R+PA++DR  MPY
Sbjct: 364  LMTTHNLIFGGTETVGTTLRHAFLVLMKYPKVQARVQEEIDRVVGRARLPALEDRAAMPY 423

Query: 1277 LDAVVHEIQRFIDLIPLHLP 1336
             DAV+HE+QRF D+IP++LP
Sbjct: 424  TDAVIHEVQRFADVIPMNLP 443


>ref|NP_001006653.1| cytochrome P450 2B11 [Canis lupus familiaris].
          Length = 494

 Score =  347 bits (890), Expect = 1e-95
 Identities = 171/339 (50%), Positives = 231/339 (68%), Gaps = 1/339 (0%)
 Frame = +2

Query: 323  LPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVVLHGYKAVKEVLL 502
            LPPGP PLPI+GN  Q+D K + KSF  L E+YG VFTVYLG RR V+L G  A++E L+
Sbjct: 30   LPPGPRPLPILGNFLQMDRKGLLKSFLRLQEKYGDVFTVYLGPRRTVMLCGIDAIREALV 89

Query: 503  HYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGMGKQGNEQRIQRE 679
                 FSGRG+I   + V +  GV+F NG  W+  RRFSL T+RDFGMGK+  E+RIQ E
Sbjct: 90   DNAEAFSGRGKIAVVEPVFQGYGVVFANGERWKTLRRFSLATMRDFGMGKRSVEERIQEE 149

Query: 680  AHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLRLMSMFNENFYLL 859
            A  L+E LRKT G   DPTF       N+I  I+F + F Y D   LRLM++F  +F L+
Sbjct: 150  AQCLVEELRKTEGVLQDPTFFFHSMTANIICSIVFGKRFGYKDPEFLRLMNLFYVSFALI 209

Query: 860  STGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLEPSCPRDFTDTLL 1039
            S+   Q++  F  +L+Y PG+HR++  N+ EIK +    V+ HR++L+PS PRDF D  L
Sbjct: 210  SSFSSQMFELFHSFLKYFPGTHRQVYNNLQEIKAFIARMVEKHRETLDPSAPRDFIDAYL 269

Query: 1040 MEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKYPEVEEKLHEEID 1219
            + M+KEK      +   N+  T   +FFAGTETTSTTLRYG L+++KYP + E++++EID
Sbjct: 270  IRMDKEKAEPSSEFHHRNLIDTALSLFFAGTETTSTTLRYGFLLMLKYPHIAERIYKEID 329

Query: 1220 RVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            +VIGP+R+P++ DR  MPY DAV+HEIQRF DL+P+ +P
Sbjct: 330  QVIGPHRLPSLDDRAKMPYTDAVIHEIQRFGDLLPIGVP 368


>ref|NP_001032422.1| cytochrome P450 family 2 subfamily A polypeptide 13 [Canis lupus
            familiaris].
          Length = 494

 Score =  347 bits (890), Expect = 1e-95
 Identities = 173/348 (49%), Positives = 237/348 (68%), Gaps = 1/348 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+WK      KLPPGP PLP +GN  QL+ + +  S   ++ERYGPVFT++LG R +VV
Sbjct: 21   MSVWKQRKLGGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRPVVV 80

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            L G++AVKE L+    EFSGRGE  TF  + K  GV F+NG   +  RRFS+TTLRDFG+
Sbjct: 81   LCGHEAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSITTLRDFGV 140

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+G E+RIQ EA FL+EALR T G   DPTF +     NVIS I+F   FDY DK  L 
Sbjct: 141  GKRGIEERIQEEAGFLIEALRGTRGAFIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLS 200

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            L+ M   +F   +T   QLY  F   +++LPG  ++  K +  ++D+  ++V+ ++ +L+
Sbjct: 201  LLRMMLGSFQFTATSMGQLYEMFYSVMKHLPGPQQQAFKELQGLEDFITKKVEQNQRTLD 260

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
            P+ PRDF D+ L+ M++E+ +    + L N+ +T  ++FFAGTET STTLRYG L+LMK+
Sbjct: 261  PNSPRDFIDSFLIRMQEEQNNPNTEFYLKNLVLTTLNLFFAGTETVSTTLRYGFLLLMKH 320

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPL 1327
            P+VE K+HEEIDRVIG NR P  +DR  MPY +AV+HEIQRF D+IP+
Sbjct: 321  PDVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQRFGDMIPM 368


>ref|NP_001041492.1| hypothetical protein LOC484493 [Canis lupus familiaris].
          Length = 494

 Score =  345 bits (886), Expect = 4e-95
 Identities = 174/347 (50%), Positives = 238/347 (68%), Gaps = 1/347 (0%)
 Frame = +2

Query: 296  WKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVVLHG 475
            WK +    KLPPGP PLP +GN  QL+++ +  SF  +++RYGPVFT++LG RR+VVL G
Sbjct: 27   WKLLE---KLPPGPTPLPFIGNYLQLNIQQMSDSFMKISKRYGPVFTIHLGPRRVVVLCG 83

Query: 476  YKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGMGKQ 652
            Y+AVKE L+    EFSGRG   TF  + K  GV F+NG   +  RRFS+TTLRDFG+GK+
Sbjct: 84   YEAVKEALVDQAEEFSGRGAQATFDTLFKGYGVTFSNGERAKQLRRFSITTLRDFGVGKR 143

Query: 653  GNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLRLMS 832
            G E+RIQ EA FL+EAL+ T G   DPTF +     NVIS I+F   FDY DK  L L+ 
Sbjct: 144  GIEERIQEEAGFLIEALQGTRGAFIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLR 203

Query: 833  MFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLEPSC 1012
            M   +F   +T   QL   F   ++YLPG  ++ +K +  ++D+  ++V+ ++ +L+P+ 
Sbjct: 204  MMLGSFQFTATSMGQLCEMFHSVIKYLPGPQQQAIKELQGLEDFITKKVEQNQRTLDPNS 263

Query: 1013 PRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKYPEV 1192
            PRDF D+ L+ M++E+ +    + L N+ +T  ++FFAGTET STTLRYG L+LMK+P+V
Sbjct: 264  PRDFIDSFLIRMQEEQNNPNTEFHLKNLVLTTLNLFFAGTETVSTTLRYGFLLLMKHPDV 323

Query: 1193 EEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHL 1333
            E K+HEEIDRVIG NR P  +DR  MPY +AV+HEIQRF D+IPL L
Sbjct: 324  EAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQRFGDIIPLSL 370


>ref|XP_855605.1| PREDICTED: cytochrome P450 2B11 [Canis familiaris].
          Length = 494

 Score =  345 bits (886), Expect = 4e-95
 Identities = 170/339 (50%), Positives = 231/339 (68%), Gaps = 1/339 (0%)
 Frame = +2

Query: 323  LPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVVLHGYKAVKEVLL 502
            LPPGP PLPI+GN  Q+D K + KSF  L E+YG VFTVYLG RR V+L G  A++E L+
Sbjct: 30   LPPGPRPLPILGNFLQMDRKGLLKSFLRLQEKYGDVFTVYLGPRRTVMLCGIDAIREALV 89

Query: 503  HYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGMGKQGNEQRIQRE 679
                 FSGRG+I   + V +  GV+F NG  W+  RRFSL T+RDFGMGK+  E+RIQ E
Sbjct: 90   DNAEAFSGRGKIAVVEPVFQGYGVVFANGERWKTLRRFSLATMRDFGMGKRSVEERIQEE 149

Query: 680  AHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLRLMSMFNENFYLL 859
            A  L+E LRKT G   DPTF       N+I  I+F + F Y D   LRLM++F  +F L+
Sbjct: 150  AQCLVEELRKTEGVLQDPTFFFHSMTANIICSIVFGKRFGYKDPEFLRLMNLFYVSFALI 209

Query: 860  STGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLEPSCPRDFTDTLL 1039
            S+   Q++  F  +L+Y PG+HR++  N+ EIK +    V+ HR++L+PS PRDF D  L
Sbjct: 210  SSFSSQMFELFHSFLKYFPGTHRQVYNNLQEIKAFIARMVEKHRETLDPSAPRDFIDAYL 269

Query: 1040 MEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKYPEVEEKLHEEID 1219
            + M+KEK      +   N+  +   +FFAGTETTSTTLRYG L+++KYP + E++++EID
Sbjct: 270  IRMDKEKAEPSSEFHHRNLIDSALSLFFAGTETTSTTLRYGFLLMLKYPHIAERIYKEID 329

Query: 1220 RVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            +VIGP+R+P++ DR  MPY DAV+HEIQRF DL+P+ +P
Sbjct: 330  QVIGPHRLPSLDDRAKMPYTDAVIHEIQRFGDLLPIGVP 368


>ref|XP_533661.2| PREDICTED: similar to cytochrome P450 monooxygenase CYP2T1 [Canis
            familiaris].
          Length = 495

 Score =  308 bits (789), Expect = 8e-84
 Identities = 150/339 (44%), Positives = 223/339 (65%), Gaps = 1/339 (0%)
 Frame = +2

Query: 323  LPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVVLHGYKAVKEVLL 502
            LPPGP PLP++GN+ QL+ + + ++   L+ R+GPVFTV LG R  VVL GY A+++ L+
Sbjct: 34   LPPGPTPLPLLGNLLQLESRRLDRALMELSGRWGPVFTVRLGPRPAVVLCGYSALRDALV 93

Query: 503  HYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGMGKQGNEQRIQRE 679
               + FSGRG +  F+      G++F+NG  WR  R F+L  L++FG+G +  E+RI  E
Sbjct: 94   LQADAFSGRGAMAVFERFTHGNGIVFSNGLRWRTLRNFALGALKEFGLGTRTIEERILEE 153

Query: 680  AHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLRLMSMFNENFYLL 859
            A  LL   + T G PFDP  L+G A  NVI  ++F   + Y D    RL+ +FN+NF ++
Sbjct: 154  AACLLGEFQATTGAPFDPRRLLGNAVSNVICSVVFGNRYGYEDPEFQRLLDLFNDNFRIM 213

Query: 860  STGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLEPSCPRDFTDTLL 1039
            S+ W ++YN F   L +LPG H ++ +N +E++ +  E+++ H+ + +P  PRDF D  L
Sbjct: 214  SSRWGEMYNVFPTLLDWLPGPHHRIFQNFTELRVFISEQIQRHQQTRQPGKPRDFIDCFL 273

Query: 1040 MEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKYPEVEEKLHEEID 1219
             +M+KE+   E  +  + + +T  ++FF GTETTSTTLRYGLLIL+KYPEV  K+  E+D
Sbjct: 274  DQMDKEQNDPESHFQEETLVMTTHNLFFGGTETTSTTLRYGLLILLKYPEVAAKVQAELD 333

Query: 1220 RVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
             V+G +R P + DR  +PY +AV+HEIQRFI ++PL LP
Sbjct: 334  AVVGQSRTPRLGDREHLPYTNAVLHEIQRFISVLPLGLP 372


  Database: RefSeq49_CP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,874,504
  Number of sequences in database:  33,336
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33336
Number of Hits to DB: 45,238,084
Number of extensions: 1213614
Number of successful extensions: 4168
Number of sequences better than 1.0e-05: 32
Number of HSP's gapped: 4121
Number of HSP's successfully gapped: 32
Length of query: 445
Length of database: 18,874,504
Length adjustment: 106
Effective length of query: 339
Effective length of database: 15,340,888
Effective search space: 5200561032
Effective search space used: 5200561032
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007014
         (1337 letters)

Database: RefSeq49_HP.fasta 
           32,964 sequences; 18,297,164 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_000764.1| cytochrome P450 2E1 [Homo sapiens].                  598   e-171
Alignment   gi|NP_000763.1| cytochrome P450 2C18 isoform 1 [Homo sapiens].       412   e-115
Alignment   gi|NP_000762.2| cytochrome P450 2C9 [Homo sapiens].                  405   e-113
Alignment   gi|NP_000760.1| cytochrome P450 2C19 [Homo sapiens].                 405   e-113
Alignment   gi|NP_000761.3| cytochrome P450 2C8 isoform a [Homo sapiens].        398   e-111
Alignment   gi|NP_000757.2| cytochrome P450 2A13 [Homo sapiens].                 350   1e-96
Alignment   gi|NP_000753.3| cytochrome P450 2A6 [Homo sapiens].                  346   3e-95
Alignment   gi|NP_000758.1| cytochrome P450 2B6 [Homo sapiens].                  344   9e-95
Alignment   gi|NP_000755.2| cytochrome P450 2A7 isoform 1 [Homo sapiens].        343   3e-94
Alignment   gi|NP_001185784.1| cytochrome P450 2C8 isoform b [Homo sapiens].     333   2e-91

>ref|NP_000764.1| cytochrome P450 2E1 [Homo sapiens].
          Length = 493

 Score =  598 bits (1543), Expect = e-171
 Identities = 274/369 (74%), Positives = 326/369 (88%)
 Frame = +2

Query: 230  MTALGIXXXXXXXXXXXXXISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTML 409
            M+ALG+             +S+W+ +HSSW LPPGPFPLPI+GN+FQL+LKNIPKSFT L
Sbjct: 1    MSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60

Query: 410  AERYGPVFTVYLGSRRIVVLHGYKAVKEVLLHYKNEFSGRGEIPTFQVHKDKGVIFNNGP 589
            A+R+GPVFT+Y+GS+R+VV+HGYKAVKE LL YK+EFSGRG++P F  H+D+G+IFNNGP
Sbjct: 61   AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGP 120

Query: 590  TWRDTRRFSLTTLRDFGMGKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVI 769
            TW+D RRFSLTTLR++GMGKQGNE RIQREAHFLLEALRKT GQPFDPTFLIGCAPCNVI
Sbjct: 121  TWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVI 180

Query: 770  SDILFRQHFDYNDKTCLRLMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNIS 949
            +DILFR+HFDYND+  LRLM +FNENF+LLST W+QLYNNF  +L YLPGSHRK++KN++
Sbjct: 181  ADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQLYNNFPSFLHYLPGSHRKVIKNVA 240

Query: 950  EIKDYALERVKDHRDSLEPSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAG 1129
            E+K+Y  ERVK+H  SL+P+CPRD TD LL+EMEKEK+SAE +YT+D I VTVAD+FFAG
Sbjct: 241  EVKEYVSERVKEHHQSLDPNCPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAG 300

Query: 1130 TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRF 1309
            TETTSTTLRYGLLILMKYPE+EEKLHEEIDRVIGP+RIPAIKDR +MPY+DAVVHEIQRF
Sbjct: 301  TETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRF 360

Query: 1310 IDLIPLHLP 1336
            I L+P +LP
Sbjct: 361  ITLVPSNLP 369


>ref|NP_000763.1| cytochrome P450 2C18 isoform 1 [Homo sapiens].
          Length = 490

 Score =  412 bits (1058), Expect = e-115
 Identities = 194/351 (55%), Positives = 259/351 (73%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+W+      +LP GP PLPI+GNI QLD+K++ KS T  ++ YGPVFTVY G + IVV
Sbjct: 17   LSLWRQSSGRGRLPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+ +  EFSGRG  P  + V+K  G++F+NG  W++ RRF L TLR+FGM
Sbjct: 77   LHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R+Q EA  L+E LRKT+  P DPTF++GCAPCNVI  ++F   FDY D+  L 
Sbjct: 137  GKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLN 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM  FNEN  +LS+ WIQ+ NNF   + YLPGSH K+ +N + IK Y LER+K+H++SL+
Sbjct: 197  LMEKFNENLRILSSPWIQVCNNFPALIDYLPGSHNKIAENFAYIKSYVLERIKEHQESLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             +  RDF D  L++ME+EK++ +  +T++++  TV DMF AGTETTSTTLRYGLL+L+KY
Sbjct: 257  MNSARDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKY 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV  K+ EEI+ V+G NR P ++DR  MPY DAVVHEIQR+IDL+P +LP
Sbjct: 317  PEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLP 367


>ref|NP_000762.2| cytochrome P450 2C9 [Homo sapiens].
          Length = 490

 Score =  405 bits (1042), Expect = e-113
 Identities = 191/351 (54%), Positives = 258/351 (73%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+W+      KLPPGP PLP++GNI Q+ +K+I KS T L++ YGPVFT+Y G + IVV
Sbjct: 17   LSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+    EFSGRG  P  +  ++  G++F+NG  W++ RRFSL TLR+FGM
Sbjct: 77   LHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R+Q EA  L+E LRKT   P DPTF++GCAPCNVI  I+F + FDY D+  L 
Sbjct: 137  GKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLN 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM   NEN  +LS+ WIQ+ NNFS  + Y PG+H KL+KN++ +K Y LE+VK+H++S++
Sbjct: 197  LMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + P+DF D  LM+MEKEK++    +T++++  T  D+F AGTETTSTTLRY LL+L+K+
Sbjct: 257  MNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKH 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV  K+ EEI+RVIG NR P ++DR  MPY DAVVHE+QR+IDL+P  LP
Sbjct: 317  PEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLP 367


>ref|NP_000760.1| cytochrome P450 2C19 [Homo sapiens].
          Length = 490

 Score =  405 bits (1042), Expect = e-113
 Identities = 190/351 (54%), Positives = 258/351 (73%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +SIW+      KLPPGP PLP++GNI Q+D+K++ KS T L++ YGPVFT+Y G  R+VV
Sbjct: 17   LSIWRQSSGRGKLPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+ VKE L+    EFSGRG  P  +  ++  G++F+NG  W++ RRFSL TLR+FGM
Sbjct: 77   LHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R+Q EA  L+E LRKT   P DPTF++GCAPCNVI  I+F++ FDY D+  L 
Sbjct: 137  GKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLN 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM   NEN  ++ST WIQ+ NNF   + Y PG+H KL+KN++ ++   LE+VK+H++S++
Sbjct: 197  LMEKLNENIRIVSTPWIQICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRDF D  L++MEKEK + +  +T++N+ +T AD+  AGTETTSTTLRY LL+L+K+
Sbjct: 257  INNPRDFIDCFLIKMEKEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKH 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV  K+ EEI+RVIG NR P ++DR  MPY DAVVHE+QR+IDLIP  LP
Sbjct: 317  PEVTAKVQEEIERVIGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLP 367


>ref|NP_000761.3| cytochrome P450 2C8 isoform a [Homo sapiens].
          Length = 490

 Score =  398 bits (1023), Expect = e-111
 Identities = 192/350 (54%), Positives = 255/350 (72%), Gaps = 1/350 (0%)
 Frame = +2

Query: 290  SIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVVL 469
            S+W+      KLPPGP PLPI+GN+ Q+D+K+I KSFT  ++ YGPVFTVY G   IVV 
Sbjct: 18   SLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVF 77

Query: 470  HGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGMG 646
            HGY+AVKE L+    EFSGRG  P  Q + K  G+I +NG  W++ RRFSLTTLR+FGMG
Sbjct: 78   HGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMG 137

Query: 647  KQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLRL 826
            K+  E R+Q EAH L+E LRKT   P DPTF++GCAPCNVI  ++F++ FDY D+  L L
Sbjct: 138  KRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTL 197

Query: 827  MSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLEP 1006
            M  FNENF +L++ WIQ+ NNF   +   PG+H K++KN++  + Y  E+VK+H+ SL+ 
Sbjct: 198  MKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDV 257

Query: 1007 SCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKYP 1186
            + PRDF D  L++ME+EK + +  + ++N+  TVAD+F AGTETTSTTLRYGLL+L+K+P
Sbjct: 258  NNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHP 317

Query: 1187 EVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            EV  K+ EEID VIG +R P ++DR  MPY DAVVHEIQR+ DL+P  +P
Sbjct: 318  EVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVP 367


>ref|NP_000757.2| cytochrome P450 2A13 [Homo sapiens].
          Length = 494

 Score =  350 bits (899), Expect = 1e-96
 Identities = 174/350 (49%), Positives = 239/350 (68%), Gaps = 1/350 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+W+   S  KLPPGP PLP +GN  QL+ + +  S   ++ERYGPVFT++LG RR+VV
Sbjct: 21   MSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVV 80

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            L G+ AVKE L+    EFSGRGE  TF  + K  GV F+NG   +  RRFS+ TLR FG+
Sbjct: 81   LCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGV 140

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+G E+RIQ EA FL++ALR THG   DPTF +     NVIS I+F   FDY DK  L 
Sbjct: 141  GKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLS 200

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            L+ M   +F   +T   QLY  FS  +++LPG  ++  K +  ++D+  ++V+ ++ +L+
Sbjct: 201  LLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLEDFIAKKVEHNQRTLD 260

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
            P+ PRDF D+ L+ M++E+ +    + L N+ +T  ++FFAGTET STTLRYG L+LMK+
Sbjct: 261  PNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKH 320

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHL 1333
            PEVE K+HEEIDRVIG NR P  +DR  MPY +AV+HEIQRF D++P+ L
Sbjct: 321  PEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGL 370


>ref|NP_000753.3| cytochrome P450 2A6 [Homo sapiens].
          Length = 494

 Score =  346 bits (887), Expect = 3e-95
 Identities = 173/350 (49%), Positives = 238/350 (68%), Gaps = 1/350 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+W+   S  KLPPGP PLP +GN  QL+ + +  S   ++ERYGPVFT++LG RR+VV
Sbjct: 21   MSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVV 80

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            L G+ AV+E L+    EFSGRGE  TF  V K  GV+F+NG   +  RRFS+ TLRDFG+
Sbjct: 81   LCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGV 140

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+G E+RIQ EA FL++ALR T G   DPTF +     NVIS I+F   FDY DK  L 
Sbjct: 141  GKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLS 200

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            L+ M    F   ST   QLY  FS  +++LPG  ++  + +  ++D+  ++V+ ++ +L+
Sbjct: 201  LLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQGLEDFIAKKVEHNQRTLD 260

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
            P+ PRDF D+ L+ M++E+ +    + L N+ +T  ++F  GTET STTLRYG L+LMK+
Sbjct: 261  PNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKH 320

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHL 1333
            PEVE K+HEEIDRVIG NR P  +DR  MPY++AV+HEIQRF D+IP+ L
Sbjct: 321  PEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSL 370


>ref|NP_000758.1| cytochrome P450 2B6 [Homo sapiens].
          Length = 491

 Score =  344 bits (883), Expect = 9e-95
 Identities = 166/349 (47%), Positives = 242/349 (69%), Gaps = 1/349 (0%)
 Frame = +2

Query: 293  IWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVVLH 472
            + +H ++  +LPPGP PLP++GN+ Q+D + + KSF    E+YG VFTV+LG R +V+L 
Sbjct: 20   VQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVHLGPRPVVMLC 79

Query: 473  GYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGMGK 649
            G +A++E L+     FSGRG+I       +  GVIF NG  W+  RRFS+TT+RDFGMGK
Sbjct: 80   GVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGK 139

Query: 650  QGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLRLM 829
            +  E+RIQ EA  L+E LRK+ G   DPTFL      N+I  I+F + F Y D+  L+++
Sbjct: 140  RSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKML 199

Query: 830  SMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLEPS 1009
            ++F + F L+S+ + QL+  FSG+L+Y PG+HR++ KN+ EI  Y    V+ HR++L+PS
Sbjct: 200  NLFYQTFSLISSVFGQLFELFSGFLKYFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPS 259

Query: 1010 CPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKYPE 1189
             P+D  DT L+ MEKEK +A   ++  N+ +    +FFAGTETTSTTLRYG L+++KYP 
Sbjct: 260  APKDLIDTYLLHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPH 319

Query: 1190 VEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            V E+++ EI++VIGP+R P + DR  MPY +AV++EIQRF DL+P+ +P
Sbjct: 320  VAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVP 368


>ref|NP_000755.2| cytochrome P450 2A7 isoform 1 [Homo sapiens].
          Length = 494

 Score =  343 bits (879), Expect = 3e-94
 Identities = 172/350 (49%), Positives = 238/350 (68%), Gaps = 1/350 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+W+   S  KLPPGP PLP +GN  QL+ ++I  S    +E YGPVFT++LG RR+VV
Sbjct: 21   MSVWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHICDSIMKFSECYGPVFTIHLGPRRVVV 80

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            L G+ AV+E L+    EFSGRGE  TF  V K  GV F+NG   +   RF++ TLRDFG+
Sbjct: 81   LCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDFGV 140

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+G E+RIQ E+ FL+EA+R THG   DPTF +     NVIS I+F   FDY DK  L 
Sbjct: 141  GKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLS 200

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            L+SM    F   ST   QLY  FS  +++LPG  ++  K +  ++D+  ++V+ ++ +L+
Sbjct: 201  LLSMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFKLLQGLEDFIAKKVEHNQRTLD 260

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
            P+ P+DF D+ L+ M++E+ +    + L N+ ++  ++F AGTET STTLRYG L+LMK+
Sbjct: 261  PNSPQDFIDSFLIHMQEEEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKH 320

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHL 1333
            PEVE K+HEEIDRVIG NR P  +DR  MPY++AV+HEIQRF D+IP+ L
Sbjct: 321  PEVEAKVHEEIDRVIGKNRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSL 370


>ref|NP_001185784.1| cytochrome P450 2C8 isoform b [Homo sapiens].
          Length = 420

 Score =  333 bits (855), Expect = 2e-91
 Identities = 161/294 (54%), Positives = 215/294 (73%), Gaps = 1/294 (0%)
 Frame = +2

Query: 458  IVVLHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRD 634
            IVV HGY+AVKE L+    EFSGRG  P  Q + K  G+I +NG  W++ RRFSLTTLR+
Sbjct: 4    IVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRN 63

Query: 635  FGMGKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKT 814
            FGMGK+  E R+Q EAH L+E LRKT   P DPTF++GCAPCNVI  ++F++ FDY D+ 
Sbjct: 64   FGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQN 123

Query: 815  CLRLMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRD 994
             L LM  FNENF +L++ WIQ+ NNF   +   PG+H K++KN++  + Y  E+VK+H+ 
Sbjct: 124  FLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQA 183

Query: 995  SLEPSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLIL 1174
            SL+ + PRDF D  L++ME+EK + +  + ++N+  TVAD+F AGTETTSTTLRYGLL+L
Sbjct: 184  SLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLL 243

Query: 1175 MKYPEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            +K+PEV  K+ EEID VIG +R P ++DR  MPY DAVVHEIQR+ DL+P  +P
Sbjct: 244  LKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVP 297


  Database: RefSeq49_HP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,297,164
  Number of sequences in database:  32,964
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 32964
Number of Hits to DB: 44,313,553
Number of extensions: 1172616
Number of successful extensions: 4033
Number of sequences better than 1.0e-05: 41
Number of HSP's gapped: 3975
Number of HSP's successfully gapped: 43
Length of query: 445
Length of database: 18,297,164
Length adjustment: 106
Effective length of query: 339
Effective length of database: 14,802,980
Effective search space: 5018210220
Effective search space used: 5018210220
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007014
         (1337 letters)

Database: RefSeq49_MP.fasta 
           30,036 sequences; 15,617,559 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_067257.1| cytochrome P450 2E1 [Mus musculus].                  578   e-165
Alignment   gi|NP_001161377.1| cytochrome P450, family 2, subfamily c, poly...   404   e-113
Alignment   gi|NP_001001446.3| cytochrome P450, family 2, subfamily c, poly...   404   e-113
Alignment   gi|NP_082467.2| cytochrome P450, family 2, subfamily c, polypep...   396   e-110
Alignment   gi|NP_031841.3| cytochrome P450 2C29 [Mus musculus].                 396   e-110
Alignment   gi|NP_034133.2| cytochrome P450 2C39 [Mus musculus].                 392   e-109
Alignment   gi|NP_001011707.1| cytochrome P450, family 2, subfamily c, poly...   392   e-109
Alignment   gi|NP_082365.1| cytochrome P450 2C55 [Mus musculus].                 390   e-108
Alignment   gi|NP_034132.2| cytochrome P450 2C38 [Mus musculus].                 390   e-108
Alignment   gi|NP_598905.2| cytochrome P450 2C50 isoform 1 [Mus musculus].       386   e-107

>ref|NP_067257.1| cytochrome P450 2E1 [Mus musculus].
          Length = 493

 Score =  578 bits (1490), Expect = e-165
 Identities = 270/369 (73%), Positives = 319/369 (86%)
 Frame = +2

Query: 230  MTALGIXXXXXXXXXXXXXISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTML 409
            M  LGI             +SIWK I+ SW LPPGPFP+P  GNIFQLDLK+IPKS T L
Sbjct: 1    MAVLGITVALLVWIATLLLVSIWKQIYRSWNLPPGPFPIPFFGNIFQLDLKDIPKSLTKL 60

Query: 410  AERYGPVFTVYLGSRRIVVLHGYKAVKEVLLHYKNEFSGRGEIPTFQVHKDKGVIFNNGP 589
            A+R+GPVFT++LG RRIVVLHGYKAVKEVLL++KNEFSGRG+IP FQ +K+KG+IFNNGP
Sbjct: 61   AKRFGPVFTLHLGQRRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYKNKGIIFNNGP 120

Query: 590  TWRDTRRFSLTTLRDFGMGKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVI 769
            TW+D RRFSL+ LRD+GMGKQGNE RIQREAHFL+E L+KT GQPFDPTFLIGCAPCNVI
Sbjct: 121  TWKDVRRFSLSILRDWGMGKQGNEARIQREAHFLVEELKKTKGQPFDPTFLIGCAPCNVI 180

Query: 770  SDILFRQHFDYNDKTCLRLMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNIS 949
            +DILF + FDY+DK CL LMS+FNENFYLLST WIQ YN FS YL+YLPGSHRK+MKN+S
Sbjct: 181  ADILFNKRFDYDDKKCLELMSLFNENFYLLSTPWIQAYNYFSDYLQYLPGSHRKVMKNVS 240

Query: 950  EIKDYALERVKDHRDSLEPSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAG 1129
            EI+ Y L + K+H  SL+ +CPRD TD LL+EMEKEK+S EP+YT++NI+VT+AD+FFAG
Sbjct: 241  EIRQYTLGKAKEHLKSLDINCPRDVTDCLLIEMEKEKHSQEPMYTMENISVTLADLFFAG 300

Query: 1130 TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRF 1309
            TETTSTTLRYGLLILMKYPE+EEKLHEEIDRVIGP+R PA++DR++MPY+DAVVHEIQRF
Sbjct: 301  TETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRAPAVRDRMNMPYMDAVVHEIQRF 360

Query: 1310 IDLIPLHLP 1336
            I+L+P +LP
Sbjct: 361  INLVPSNLP 369


>ref|NP_001161377.1| cytochrome P450, family 2, subfamily c, polypeptide 44 isoform 2 [Mus
            musculus].
          Length = 456

 Score =  404 bits (1039), Expect = e-113
 Identities = 185/351 (52%), Positives = 264/351 (75%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+W  + +  +LPPGP PLPI+GNI QLDLK+IP S + LA+ YGPV+T+Y GS   VV
Sbjct: 21   LSVWTKMRTGGRLPPGPTPLPIIGNILQLDLKDIPASLSKLAKEYGPVYTLYFGSWPTVV 80

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY  VKE LL+  +EF GRG +P  +   K  G++F+ G  W+  RRFSL TL++FGM
Sbjct: 81   LHGYDVVKEALLNQGDEFLGRGPLPIIEDSQKGHGIVFSEGERWKLLRRFSLMTLKNFGM 140

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E+R+Q EA  L+E L KT  QPFDPTF++ CAPCNVI  ILF + F YNDKT L 
Sbjct: 141  GKRSLEERVQEEARCLVEELHKTEAQPFDPTFILACAPCNVICSILFNERFPYNDKTFLN 200

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM + N+NFY L++ WIQ+YN +   ++Y+PG HR+  K +  +K++ LE+VK+H++SL+
Sbjct: 201  LMDLLNKNFYQLNSIWIQMYNLWPTIMKYIPGKHREFSKRLGGVKNFILEKVKEHQESLD 260

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
            P+ PRD+ D  L ++E+EK++ +  + L+N+A+  +++F AGTETTSTTLR+GLL+L+K+
Sbjct: 261  PANPRDYIDCFLSKIEEEKHNLKSDFNLENLAICGSNLFTAGTETTSTTLRFGLLLLVKH 320

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV+ K+HEE+DRVIG ++ P++KD++ +PY DAV+HEIQR+I L+P  LP
Sbjct: 321  PEVQAKVHEELDRVIGRHQPPSMKDKMKLPYTDAVLHEIQRYITLLPSSLP 371


>ref|NP_001001446.3| cytochrome P450, family 2, subfamily c, polypeptide 44 isoform 1 [Mus
            musculus].
          Length = 494

 Score =  404 bits (1039), Expect = e-113
 Identities = 185/351 (52%), Positives = 264/351 (75%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+W  + +  +LPPGP PLPI+GNI QLDLK+IP S + LA+ YGPV+T+Y GS   VV
Sbjct: 21   LSVWTKMRTGGRLPPGPTPLPIIGNILQLDLKDIPASLSKLAKEYGPVYTLYFGSWPTVV 80

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY  VKE LL+  +EF GRG +P  +   K  G++F+ G  W+  RRFSL TL++FGM
Sbjct: 81   LHGYDVVKEALLNQGDEFLGRGPLPIIEDSQKGHGIVFSEGERWKLLRRFSLMTLKNFGM 140

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E+R+Q EA  L+E L KT  QPFDPTF++ CAPCNVI  ILF + F YNDKT L 
Sbjct: 141  GKRSLEERVQEEARCLVEELHKTEAQPFDPTFILACAPCNVICSILFNERFPYNDKTFLN 200

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM + N+NFY L++ WIQ+YN +   ++Y+PG HR+  K +  +K++ LE+VK+H++SL+
Sbjct: 201  LMDLLNKNFYQLNSIWIQMYNLWPTIMKYIPGKHREFSKRLGGVKNFILEKVKEHQESLD 260

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
            P+ PRD+ D  L ++E+EK++ +  + L+N+A+  +++F AGTETTSTTLR+GLL+L+K+
Sbjct: 261  PANPRDYIDCFLSKIEEEKHNLKSDFNLENLAICGSNLFTAGTETTSTTLRFGLLLLVKH 320

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV+ K+HEE+DRVIG ++ P++KD++ +PY DAV+HEIQR+I L+P  LP
Sbjct: 321  PEVQAKVHEELDRVIGRHQPPSMKDKMKLPYTDAVLHEIQRYITLLPSSLP 371


>ref|NP_082467.2| cytochrome P450, family 2, subfamily c, polypeptide 65 [Mus
            musculus].
          Length = 490

 Score =  396 bits (1017), Expect = e-110
 Identities = 191/351 (54%), Positives = 253/351 (72%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+W+       LPPGP PLPI+GNI QLDLK+I KS    ++ YGPVFT+YLG    VV
Sbjct: 17   LSLWRQNSQRRNLPPGPTPLPIIGNILQLDLKDISKSLRNFSKVYGPVFTLYLGRNPAVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTF-QVHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE    +  EF+GRG  P F +  K+ GV+F++G TW++ RRFSL TLR+FGM
Sbjct: 77   LHGYEAVKEAFTDHGEEFAGRGVFPVFDKFKKNCGVVFSSGRTWKEMRRFSLMTLRNFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            G++  E RIQ EA  L++ LRKT G+P DPTF++GCAPCNVI  I+F+  FDY D+  L 
Sbjct: 137  GRRSIEDRIQEEARCLVDELRKTKGEPCDPTFILGCAPCNVICSIVFQNRFDYKDQEFLT 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
             + + NEN  +LS+ WIQ+ NNF   + YLPG HRKL KN +  + Y L +VK H++SL+
Sbjct: 197  FLDILNENVEILSSPWIQICNNFPAVIDYLPGRHRKLHKNFAFAEHYFLSKVKQHQESLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRDF D  L++ME+EK++ +  +T +N+  T +D+F AGTETTSTTLRY LL+L+KY
Sbjct: 257  INNPRDFIDCFLIKMEQEKHNPKTEFTCENLVFTASDLFAAGTETTSTTLRYSLLLLLKY 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV  K+ EEID VIG +R P ++DR  MPY DAV+HEIQR+IDL+P  LP
Sbjct: 317  PEVTAKVQEEIDCVIGRHRSPCMQDRHSMPYTDAVLHEIQRYIDLLPTSLP 367


>ref|NP_031841.3| cytochrome P450 2C29 [Mus musculus].
          Length = 490

 Score =  396 bits (1017), Expect = e-110
 Identities = 184/351 (52%), Positives = 255/351 (72%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+W+      KLPPGP PLPI+GN  Q+D+KNI +SFT  ++ YGPVFT+YLGS+  V+
Sbjct: 17   LSLWRQSSGRGKLPPGPTPLPIIGNFLQIDVKNISQSFTNFSKAYGPVFTLYLGSKPTVI 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+    EF+GRG  P  + + K  GV+F+NG  W++ RRF+L TLR+ GM
Sbjct: 77   LHGYEAVKEALIDRGEEFAGRGSFPMAEKIIKGFGVVFSNGNRWKEMRRFTLMTLRNLGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R+Q EA  L+E LRKT G P DPTF++ CAPCNVI  I+F+  FDY DK  L 
Sbjct: 137  GKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQNRFDYKDKEFLI 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM   NEN  +LS+ W+Q+ N+F   + Y PGSH K++KN + +K Y LE++K+H++SL+
Sbjct: 197  LMDKINENVKILSSPWLQVCNSFPSLIDYCPGSHHKIVKNFNYLKSYLLEKIKEHKESLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRDF D  L++ ++  +  +  ++L+N+A T+ D+F AGTETTSTTLRY LL+L+KY
Sbjct: 257  VTNPRDFIDYYLIKQKQVNHIEQSEFSLENLASTINDLFGAGTETTSTTLRYALLLLLKY 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            P+V  K+ EEIDRV+G +R P ++DR  MPY DA++HE+QRFIDL+P  LP
Sbjct: 317  PDVTAKVQEEIDRVVGRHRSPCMQDRSHMPYTDAMIHEVQRFIDLLPTSLP 367


>ref|NP_034133.2| cytochrome P450 2C39 [Mus musculus].
          Length = 490

 Score =  392 bits (1007), Expect = e-109
 Identities = 181/351 (51%), Positives = 254/351 (72%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+W+       LPPGP P PI+GN  Q+D+KN+ +S T  ++ YGPVFT+YLGSR  VV
Sbjct: 17   LSLWRQSCGRGSLPPGPTPFPIIGNFLQIDIKNVSQSLTNFSKAYGPVFTLYLGSRPTVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+ +  EFS RG IP  + ++   G++F+NG  W++ RRF+LTTLR+ GM
Sbjct: 77   LHGYEAVKEALIDHGEEFSDRGSIPMVEKINNGLGIVFSNGNRWKEIRRFTLTTLRNLGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R+Q EA  L+E LRKT G P DPTF++ CAPCNVI  I+F+  FDY DK  L 
Sbjct: 137  GKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQDRFDYKDKDFLM 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM   NEN  +LS+ W+Q+ NNF   + Y PGSH K++KN+  I+ Y LE++K+H++SL+
Sbjct: 197  LMEKLNENVKILSSPWLQVCNNFPLLIDYCPGSHHKVLKNVKYIRSYLLEKIKEHQESLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRDF D  L++ ++  +  +  ++L+N+A T+ ++F AGTETTSTTLRY LL+LMKY
Sbjct: 257  VTNPRDFIDYYLIKQKQANHIQQAEFSLENLACTINNLFAAGTETTSTTLRYALLLLMKY 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            P+V  K+ EEID VIG +R P ++DR  MPY DA++HE+QRFI+L+P ++P
Sbjct: 317  PDVTAKVQEEIDHVIGRHRSPCMQDRNHMPYTDAMIHEVQRFINLVPNNIP 367


>ref|NP_001011707.1| cytochrome P450, family 2, subfamily c, polypeptide 66 [Mus
            musculus].
          Length = 490

 Score =  392 bits (1007), Expect = e-109
 Identities = 191/351 (54%), Positives = 250/351 (71%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+WK       LPPGP PLPI+GNI QLDLK+I KS    ++ YGPVFT+YLG +  VV
Sbjct: 17   LSLWKQNSQRRNLPPGPTPLPIIGNILQLDLKDISKSLRNFSKVYGPVFTLYLGKKPAVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQVHKDK-GVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGYKAVKE L+ +  EF+GRG  P       + GV+F++G TW++ RRFSL TLR+FGM
Sbjct: 77   LHGYKAVKEALIDHGEEFAGRGTFPVADKFIRRCGVVFSSGRTWKEMRRFSLMTLRNFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R+Q EA  L++ LRKT G P DPTF++GCAPCNVI  I+F+  FDY D+  L 
Sbjct: 137  GKRSIEDRVQEEARCLVDELRKTKGVPCDPTFILGCAPCNVICSIVFQNRFDYKDQEFLT 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
             + + NEN  +LS+ WIQ+ NNF   + YLPG HRKL+KN    K Y L +V  H++SL+
Sbjct: 197  FIDILNENVEILSSPWIQVCNNFPAIIDYLPGRHRKLLKNFDFAKHYFLAKVIQHKESLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRDF D  L++ME+EK++ +  +T +N+  T +D+F AGTETTSTTLRY LL+L+KY
Sbjct: 257  INNPRDFIDCFLIKMEQEKHNPKTEFTCENLIFTASDLFAAGTETTSTTLRYSLLLLLKY 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV  K+  EID VIG +R P ++DR  MPY DAV+HEIQR+IDL+P  LP
Sbjct: 317  PEVTAKVQAEIDCVIGRHRSPCMQDRHSMPYTDAVLHEIQRYIDLLPTSLP 367


>ref|NP_082365.1| cytochrome P450 2C55 [Mus musculus].
          Length = 490

 Score =  390 bits (1001), Expect = e-108
 Identities = 186/351 (52%), Positives = 250/351 (71%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+W+      KLPPGP P PI+GNI Q+D+KNI KSF   ++ YGPVFT+Y GS+  VV
Sbjct: 17   LSLWRQNSGRGKLPPGPTPFPIIGNILQIDIKNISKSFNYFSKVYGPVFTLYFGSKPTVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            +HGY+AVKE L     EFSGRG    F+ ++ D GVIF+NG  W++ RRFS+ TLR FGM
Sbjct: 77   VHGYEAVKEALDDLGEEFSGRGSFQIFERINNDLGVIFSNGTKWKELRRFSIMTLRSFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E RIQ EA  L+E LRK +G   DPTF++ CAP NVI  ++F   FDY D+  L 
Sbjct: 137  GKRSIEDRIQEEASCLVEELRKANGSLCDPTFILSCAPSNVICSVIFHNRFDYKDEKFLN 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM   NENF +L++ W+Q+YN     + YLPGSH K++KN +EIK Y L RVK+H+++L+
Sbjct: 197  LMERLNENFKILNSPWMQVYNALPTLINYLPGSHNKVIKNFTEIKSYILGRVKEHQETLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
               PRDF D  L++ME+EK++    +T++++  TV D+F AGTETT+ TLRYGLL+L+K+
Sbjct: 257  MDNPRDFIDCFLIKMEQEKHNPHSEFTIESLMATVTDIFVAGTETTNITLRYGLLLLLKH 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
             EV  K+  EID VIG +R P ++DR  MPY DA+VHEIQR+IDLIP ++P
Sbjct: 317  TEVTAKVQAEIDHVIGRHRSPCMQDRTRMPYTDAMVHEIQRYIDLIPNNVP 367


>ref|NP_034132.2| cytochrome P450 2C38 [Mus musculus].
          Length = 490

 Score =  390 bits (1001), Expect = e-108
 Identities = 182/351 (51%), Positives = 253/351 (72%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+W+      +LPPGP P PI+GN  Q+D+KN  +S T  ++ YGPVFT+YLGSR IVV
Sbjct: 17   LSLWRQRSRRGRLPPGPTPFPIIGNFLQIDVKNFNQSLTNFSKTYGPVFTLYLGSRPIVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+ +  EFSGR  IP  + ++   G+ F+NG +W++TRRF+L TLR+ GM
Sbjct: 77   LHGYEAVKEALIDHGEEFSGRENIPMSEKINNGLGITFSNGNSWKETRRFTLMTLRNLGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R++ EA  L+E LRKT G P DPTF++ CAPCNVI  I+F+  FDY DK  L 
Sbjct: 137  GKRNIEDRVREEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQDRFDYKDKDFLM 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM   NEN  +LS+ W+Q+ NNF   + Y PGSH K++KN   I+ Y LE+VK+H++SL+
Sbjct: 197  LMKKLNENVKILSSPWLQVCNNFPLLIDYCPGSHHKVLKNFKYIRSYLLEKVKEHQESLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRDF D  L++ ++  +  +  Y+L+N+  T+ ++F AGTETTSTTLRY LL+LMKY
Sbjct: 257  VTNPRDFIDYFLIKQKQANHIEQAEYSLENLVCTINNLFAAGTETTSTTLRYALLLLMKY 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            P+V  K+ EEID V+G +R P ++DR  MPY DA++HE+QRFI+L+P +LP
Sbjct: 317  PDVTAKVQEEIDHVVGRHRSPCMQDRSRMPYTDAMIHEVQRFINLVPNNLP 367


>ref|NP_598905.2| cytochrome P450 2C50 isoform 1 [Mus musculus].
          Length = 490

 Score =  386 bits (992), Expect = e-107
 Identities = 185/351 (52%), Positives = 252/351 (71%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+W+      KLPPGP PLPI+GNI Q+++K+I +SFT L++ YGPV+T+YLG +  VV
Sbjct: 17   LSLWRQSSERGKLPPGPTPLPIIGNILQINVKDICQSFTNLSKVYGPVYTLYLGRKPTVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTF-QVHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+ +  EF+GRG +P F +     G+IF+ G  W++TRRFSLTTLR+ GM
Sbjct: 77   LHGYEAVKEALVDHGEEFAGRGRLPVFDKATNGMGIIFSKGNVWKNTRRFSLTTLRNLGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E R+Q EA  L+E LRKT+G P DPTF++GCAPCNVI  I+F+  FDY D+  L 
Sbjct: 137  GKRSIEDRVQEEARCLVEELRKTNGSPCDPTFILGCAPCNVICSIIFQDRFDYKDRDFLN 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM   NE   ++ST W+Q+ N F   L Y PGSH K+ KN + IK++ LE++K+H +SL+
Sbjct: 197  LMEKLNEITKIMSTPWLQVCNTFPVLLDYCPGSHNKVFKNYACIKNFLLEKIKEHEESLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRDF D  L+   +E  +      L+++A+TV D+F AGTETTSTTLRY LL+L+KY
Sbjct: 257  VTIPRDFIDYFLINGGQENGNYPLKNRLEHLAITVTDLFSAGTETTSTTLRYALLLLLKY 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            P V  K+ EEI+ VIG +R P ++DR  MPY DA++HE+QRFIDL+P  LP
Sbjct: 317  PHVTAKVQEEIEHVIGKHRRPCMQDRSHMPYTDAMIHEVQRFIDLVPNSLP 367


  Database: RefSeq49_MP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 15,617,559
  Number of sequences in database:  30,036
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 30036
Number of Hits to DB: 37,612,780
Number of extensions: 994104
Number of successful extensions: 3431
Number of sequences better than 1.0e-05: 75
Number of HSP's gapped: 3326
Number of HSP's successfully gapped: 76
Length of query: 445
Length of database: 15,617,559
Length adjustment: 105
Effective length of query: 340
Effective length of database: 12,463,779
Effective search space: 4237684860
Effective search space used: 4237684860
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007014
         (1337 letters)

Database: RefSeq49_SP.fasta 
           24,897 sequences; 11,343,932 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_999586.1| cytochrome P450 2E1 [Sus scrofa].                    721   0.0  
Alignment   gi|NP_001161307.1| cytochrome P450 2C42 [Sus scrofa].                412   e-115
Alignment   gi|XP_003359352.1| PREDICTED: LOW QUALITY PROTEIN: cytochrome P...   406   e-113
Alignment   gi|NP_999585.1| cytochrome P450 2C49 [Sus scrofa].                   404   e-113
Alignment   gi|NP_999579.1| cytochrome P450 2C33 [Sus scrofa].                   384   e-107
Alignment   gi|XP_003127188.2| PREDICTED: cytochrome P450 2G1-like isoform ...   374   e-104
Alignment   gi|NP_999578.1| cytochrome P450 2B22 [Sus scrofa].                   348   4e-96
Alignment   gi|NP_999582.1| cytochrome P450 2A19 [Sus scrofa].                   338   4e-93
Alignment   gi|XP_003128009.2| PREDICTED: cytochrome P450 2J2-like, partial...   263   2e-70
Alignment   gi|XP_003128010.2| PREDICTED: cytochrome P450 2J2-like [Sus scr...   260   1e-69

>ref|NP_999586.1| cytochrome P450 2E1 [Sus scrofa].
          Length = 495

 Score =  721 bits (1861), Expect = 0.0
 Identities = 353/369 (95%), Positives = 354/369 (95%)
 Frame = +2

Query: 230  MTALGIXXXXXXXXXXXXXISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTML 409
            MTALGI             ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTML
Sbjct: 1    MTALGITVALLVWLVTLLLISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTML 60

Query: 410  AERYGPVFTVYLGSRRIVVLHGYKAVKEVLLHYKNEFSGRGEIPTFQVHKDKGVIFNNGP 589
            AERYGPVFTVYLGSRRIVVLHGYKAVKEVLLHYKNEFSGRGEIPTFQVHKDKGVIFNNGP
Sbjct: 61   AERYGPVFTVYLGSRRIVVLHGYKAVKEVLLHYKNEFSGRGEIPTFQVHKDKGVIFNNGP 120

Query: 590  TWRDTRRFSLTTLRDFGMGKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVI 769
            TWRDTRRFSLTTLRDFGMGKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVI
Sbjct: 121  TWRDTRRFSLTTLRDFGMGKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVI 180

Query: 770  SDILFRQHFDYNDKTCLRLMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNIS 949
            SDILFRQHFDYNDKTCLRLMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNIS
Sbjct: 181  SDILFRQHFDYNDKTCLRLMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNIS 240

Query: 950  EIKDYALERVKDHRDSLEPSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAG 1129
            EIKDYALERVKDHRDSLEPSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAG
Sbjct: 241  EIKDYALERVKDHRDSLEPSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAG 300

Query: 1130 TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRF 1309
            TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPNRIPAIKDRL MPYLDAVVHEIQRF
Sbjct: 301  TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPNRIPAIKDRLVMPYLDAVVHEIQRF 360

Query: 1310 IDLIPLHLP 1336
            IDLIP +LP
Sbjct: 361  IDLIPSNLP 369


>ref|NP_001161307.1| cytochrome P450 2C42 [Sus scrofa].
          Length = 490

 Score =  412 bits (1059), Expect = e-115
 Identities = 199/351 (56%), Positives = 260/351 (74%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+WK      +LPPGP PLPI+GNI QLD+KNI KS + LAE YGPVFTVY G +  VV
Sbjct: 17   LSLWKESSGKGELPPGPTPLPILGNILQLDVKNISKSLSNLAEVYGPVFTVYFGIKPTVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            L+GY+AVKE L+    EFSGRG  P  +  HK  G+IF+NG  W++ RRFSL TLR+ GM
Sbjct: 77   LYGYEAVKEALVDLGEEFSGRGHFPVAEKTHKGLGIIFSNGKKWKEIRRFSLMTLRNLGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E RIQ EA  L+E LRKT+  P DPTF++ CAPCNVI  I+F+  FDY D+  L 
Sbjct: 137  GKRSIEDRIQEEACCLVEELRKTNASPCDPTFILDCAPCNVICSIIFQNRFDYTDQDFLT 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            L+  F+EN  +LS+ WIQ+ NNF   + Y PG H KL+KNI+ +K Y L++VK+H++SL+
Sbjct: 197  LLEKFHENLNILSSPWIQVCNNFPALIDYSPGIHNKLLKNIAYLKSYVLKKVKEHQESLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRDF D  L++ME+EK++ +  YT++N+  TV+DMF AGTETTSTT+RYGLL+L+K+
Sbjct: 257  INNPRDFIDCFLIKMEQEKHNQQSEYTIENLIATVSDMFSAGTETTSTTMRYGLLLLLKH 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV  K+ EEIDRVIG +R   ++DR  MPY DAVVHEIQR+IDL+P +LP
Sbjct: 317  PEVTAKVQEEIDRVIGRHRSACMQDRSHMPYTDAVVHEIQRYIDLVPTNLP 367


>ref|XP_003359352.1| PREDICTED: LOW QUALITY PROTEIN: cytochrome P450 2C18 [Sus scrofa].
          Length = 490

 Score =  406 bits (1044), Expect = e-113
 Identities = 194/351 (55%), Positives = 262/351 (74%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+WK      +LPPGP PLPI+GNI QL++K+I KS + L++ YGPVFTVYLG +  VV
Sbjct: 17   LSLWKQNSGKGRLPPGPTPLPILGNILQLNVKDISKSLSNLSKVYGPVFTVYLGLKPAVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+A+KE L+    EFSGRG +P  + V+K  G+IF++G  W++ RRFSL TLR+FGM
Sbjct: 77   LHGYEAMKEALIDGGEEFSGRGHLPMAERVNKGHGIIFSSGKRWKEIRRFSLMTLRNFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E+R+Q EA  L+E LRKT+  P+DPTFL+GCAPC VI  I+FR  FDY D   L 
Sbjct: 137  GKRSIEERVQEEARCLVEELRKTNASPWDPTFLLGCAPCKVICSIIFRNRFDYTDPNFLT 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            L+   NENF +LS+ WIQ+ NNF   + YLPGSH K+ KN + +K Y LE+VK+H+ SL+
Sbjct: 197  LLEKLNENFRILSSPWIQVCNNFPALIDYLPGSHNKVFKNSAYVKSYILEKVKEHQASLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + PRDF D  L++ME+EK++ +  +T +N+  T++D+F AGTETTSTTLRYGLL+L+K+
Sbjct: 257  VNDPRDFIDCFLIKMEQEKHNHQVAFTFENLIATISDLFGAGTETTSTTLRYGLLLLLKH 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            P+V  K+ +EID VI  +R P ++DR  MPY DAVVHEIQR+IDLIP+ +P
Sbjct: 317  PDVTAKVQKEIDSVIERHRSPCMQDRSRMPYTDAVVHEIQRYIDLIPISVP 367


>ref|NP_999585.1| cytochrome P450 2C49 [Sus scrofa].
          Length = 490

 Score =  404 bits (1039), Expect = e-113
 Identities = 194/351 (55%), Positives = 258/351 (73%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+WK      +LPPGP PL I+GNI QLD+K+I KS + L++ YGPVFTVY G +  VV
Sbjct: 17   LSLWKQNSGKGRLPPGPTPLSILGNILQLDVKDISKSLSNLSKVYGPVFTVYFGLKPAVV 76

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+    EFSGRG  P  + V+K  G+IF++G  W++TRRFSL TLR+FGM
Sbjct: 77   LHGYEAVKEALIDGGEEFSGRGHFPMAERVNKGHGIIFSSGKRWKETRRFSLMTLRNFGM 136

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E+R+Q EA  L+E LRKT+  P DPTFL+GCAPCNVI  I+F   FDY D   L 
Sbjct: 137  GKRSIEERVQEEARCLVEELRKTNASPCDPTFLLGCAPCNVICSIIFHNRFDYTDPNFLT 196

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            L+   NENF +LS+ W+Q+ NNF   + YLPGSH K++KN + +K Y LE+VK+H+ SL+
Sbjct: 197  LLEKLNENFRILSSPWMQVCNNFPALIDYLPGSHNKVLKNSAYVKSYILEKVKEHQASLD 256

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
               PRDF D  L++ME+EK++ +  +T +N+  T+ D+F AGTETTSTTLRYGLL+L+K+
Sbjct: 257  VKDPRDFIDCFLIKMEQEKHNHQVAFTFENLIATITDLFGAGTETTSTTLRYGLLLLLKH 316

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            P+V  K+ +EID VI  +R P ++DR  MPY DAVVHEIQR+IDLIP+ +P
Sbjct: 317  PDVTAKVQKEIDSVIERHRSPCMQDRSRMPYTDAVVHEIQRYIDLIPISVP 367


>ref|NP_999579.1| cytochrome P450 2C33 [Sus scrofa].
          Length = 494

 Score =  384 bits (987), Expect = e-107
 Identities = 181/351 (51%), Positives = 257/351 (73%), Gaps = 1/351 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+WK  H   +LPPGP PLPI+GN+ QL+LK+IP S + LA++YGPV TVY GS+  VV
Sbjct: 21   LSVWKKNHKRRRLPPGPTPLPIIGNLMQLNLKDIPASLSKLAKQYGPVCTVYFGSQPAVV 80

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            LHGY+AVKE L+   +EF GRG IP         G++F+NG  W+  RRFSL TLR+FGM
Sbjct: 81   LHGYEAVKEALIDQGDEFLGRGIIPIIDDTQGGYGLVFSNGERWKQIRRFSLMTLRNFGM 140

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E+R+Q EA FL+E LRKT  QPFDPTF++ CAPCNVI  ILF   F Y+++T L 
Sbjct: 141  GKRSLEERVQEEAQFLVEELRKTEAQPFDPTFILSCAPCNVICSILFNDRFHYDNETFLS 200

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            LM++ N NF  +S+ WIQ+YN +   +++LPG HR   K + + + + LE+VK+H+ S  
Sbjct: 201  LMNLLNANFRQISSPWIQIYNLWPQIIKHLPGEHRAFSKRLKDCRSFILEKVKEHQKSPN 260

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
             + P+D+ D  L +ME+EK + +  + L+N+  + +++F AGTETT++TLRYGLL+LMK+
Sbjct: 261  LNNPQDYIDCFLSKMEQEKQNPDSEFHLENLINSGSNLFAAGTETTTSTLRYGLLLLMKH 320

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEV+ K+HEEIDRVIG ++ P ++D++ +PY +AV+HEIQR+I L+P +LP
Sbjct: 321  PEVQAKVHEEIDRVIGRSQRPCMQDKMKLPYTEAVLHEIQRYIALLPSNLP 371


>ref|XP_003127188.2| PREDICTED: cytochrome P450 2G1-like isoform 1 [Sus scrofa].
          Length = 549

 Score =  374 bits (961), Expect = e-104
 Identities = 184/351 (52%), Positives = 244/351 (69%), Gaps = 4/351 (1%)
 Frame = +2

Query: 296  WKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVVLHG 475
            WK I    KLPPGP P+P +GN+ Q+      +SF  L E+YGPVFTVY+G R +VVL G
Sbjct: 24   WKRISKGGKLPPGPTPIPFLGNLLQVRTDATFQSFMKLREKYGPVFTVYMGPRPVVVLCG 83

Query: 476  YKAVKEVLLHYKNEFSGRGEIPT----FQVHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            ++AVKE L+   +EFSGRGE+ +    FQ H   GV   NG  WR  RRFSLT LRDFGM
Sbjct: 84   HEAVKEALIDRADEFSGRGELASVERNFQGH---GVALANGDRWRILRRFSLTILRDFGM 140

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+  E+RIQ EA FLL+ LRKT G P +PTF +     NVIS ++F   FDY DK  L+
Sbjct: 141  GKRSIEERIQEEAGFLLQELRKTKGAPIEPTFFLSRTVSNVISSVVFGSRFDYEDKQFLK 200

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            L+ M N++F  +ST W QLY+ +SG ++YLPG H ++   I E+KD+   RVK +  SL+
Sbjct: 201  LLQMINQSFIEMSTPWAQLYDMYSGIMQYLPGRHNRIYYLIEELKDFIASRVKINEASLD 260

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
            P  PRDF D  L++M ++K +    + L N+ +T  ++FFAGTET S+TLRYGLL++MK+
Sbjct: 261  PQNPRDFIDCFLIKMHQDKDNPHTEFNLKNLVLTTLNLFFAGTETVSSTLRYGLLLMMKH 320

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            PEVE K+HEEID+VIGP+RIP + DR+ MPY DAV+HEIQR  D++P+ +P
Sbjct: 321  PEVEAKIHEEIDQVIGPHRIPRVDDRVKMPYTDAVIHEIQRLTDIVPMGVP 371


>ref|NP_999578.1| cytochrome P450 2B22 [Sus scrofa].
          Length = 493

 Score =  348 bits (893), Expect = 4e-96
 Identities = 169/349 (48%), Positives = 238/349 (68%), Gaps = 1/349 (0%)
 Frame = +2

Query: 293  IWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVVLH 472
            +W H  S   LPPGP PLP +GNI Q+D K   KSF  L ERYG VFTVYLG R +V++ 
Sbjct: 19   LWGHPSSQGHLPPGPRPLPFLGNILQMDRKGFLKSFQALRERYGDVFTVYLGPRPVVMIC 78

Query: 473  GYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGMGK 649
            G +A++E L+     FSGRG+I   + + +  GVIF+NG  W+  RRFSL T+RDFG+GK
Sbjct: 79   GTEAIREALVDQAEAFSGRGKIAVVEPIFQGYGVIFSNGERWKTLRRFSLATMRDFGLGK 138

Query: 650  QGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLRLM 829
            +  E+RIQ EA  L+E LRK+ G   DPT+    +  N+I  I+F + F Y D   L+L+
Sbjct: 139  RSVEERIQEEAQCLVEELRKSQGALQDPTYYFHSSTANIICSIVFGKRFAYRDPEFLQLL 198

Query: 830  SMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLEPS 1009
             +  + F L+S+   QL+  +S +L+Y PGSHR++ KN+ ++  +    V+ HR++L+PS
Sbjct: 199  DLLFQTFLLISSFPSQLFELYSAFLKYFPGSHRQIYKNLQQVNAFIGRSVEKHRETLDPS 258

Query: 1010 CPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKYPE 1189
             PRD  D+ L+ M+KEK +    +   N+ +TV  +FFAGTETTSTTLRYG L+++KYP 
Sbjct: 259  DPRDLIDSYLLRMDKEKSNPNSEFHEQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPH 318

Query: 1190 VEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            + E++H+EIDRVIG +R PA+ DR  MPY+DAV+HE+QRF DLIP+ +P
Sbjct: 319  ITERIHKEIDRVIGSHRPPALDDRAKMPYMDAVIHEMQRFGDLIPMGVP 367


>ref|NP_999582.1| cytochrome P450 2A19 [Sus scrofa].
          Length = 494

 Score =  338 bits (867), Expect = 4e-93
 Identities = 171/350 (48%), Positives = 234/350 (66%), Gaps = 1/350 (0%)
 Frame = +2

Query: 287  ISIWKHIHSSWKLPPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVV 466
            +S+W+      KLPPGP PLP +GN  QL+ + +  S   +++RYGPVFTV+LG RRIVV
Sbjct: 21   MSVWRQRKLQGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISQRYGPVFTVHLGPRRIVV 80

Query: 467  LHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGPTWRDTRRFSLTTLRDFGM 643
            L GY AVKE L+    EFSGRGE  TF  + K  GV F+NG   +  RRFS+TTLRDFG+
Sbjct: 81   LCGYDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSITTLRDFGV 140

Query: 644  GKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLR 823
            GK+G E+RIQ EA  L+EA R T G   DPT+ +     NVIS I+F   FDY DK  L 
Sbjct: 141  GKRGIEERIQEEAGHLIEAFRGTRGAFIDPTYFLSRTVSNVISSIVFGDRFDYEDKEFLA 200

Query: 824  LMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLE 1003
            L+ M   +F   +T   QLY  F   +++LPG  ++  K++  ++D+   +V+ ++ +L+
Sbjct: 201  LLRMMLGSFQFTATSTGQLYEMFYSVMKHLPGPQQQAFKDLQGLEDFIARKVEHNQRTLD 260

Query: 1004 PSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKY 1183
            P+ PRDF D+ L+ M++EK + +  +   N+ +T  ++FFAGTET STT+RYG L+LMK 
Sbjct: 261  PNSPRDFIDSFLIRMQEEKKNPDTEFYWKNLVLTTLNLFFAGTETVSTTMRYGFLLLMKK 320

Query: 1184 PEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHL 1333
            P+VE K+HEEIDRVIG NR    +DR  MPY +AV+HEIQRF D+IP+ L
Sbjct: 321  PDVEAKVHEEIDRVIGRNRQAKFEDRAKMPYTEAVIHEIQRFGDMIPMGL 370


>ref|XP_003128009.2| PREDICTED: cytochrome P450 2J2-like, partial [Sus scrofa].
          Length = 432

 Score =  263 bits (672), Expect = 2e-70
 Identities = 130/309 (42%), Positives = 196/309 (63%), Gaps = 1/309 (0%)
 Frame = +2

Query: 413  ERYGPVFTVYLGSRRIVVLHGYKAVKEVLLHYKNEFSGRGEIPTFQ-VHKDKGVIFNNGP 589
            ++YG VF++  G+   VV+ G   +KE  +H    FS R  +P  Q V KDKGV+ +NG 
Sbjct: 3    KKYGNVFSLDFGALSSVVITGLPFIKEAFVHQDKNFSNRPIVPIQQRVFKDKGVVMSNGQ 62

Query: 590  TWRDTRRFSLTTLRDFGMGKQGNEQRIQREAHFLLEALRKTHGQPFDPTFLIGCAPCNVI 769
             W++ RRF+LTTLR+FG+GK+  E+RIQ EA +L++A+ + +GQPF+P F I  A  N+I
Sbjct: 63   VWKEQRRFALTTLRNFGLGKKSLEERIQEEAQYLIQAIGEENGQPFNPHFKINNAVSNII 122

Query: 770  SDILFRQHFDYNDKTCLRLMSMFNENFYLLSTGWIQLYNNFSGYLRYLPGSHRKLMKNIS 949
              I F + FDY D     L+ + +E   L ++ W Q+YN     +++LPG H+ L  N  
Sbjct: 123  CSITFGERFDYQDNQFQELLKLLDEVMCLQTSVWCQIYNIIPWIMKFLPGPHQTLFSNWE 182

Query: 950  EIKDYALERVKDHRDSLEPSCPRDFTDTLLMEMEKEKYSAEPIYTLDNIAVTVADMFFAG 1129
            ++K +    +++HR    P+  RDF +  L E+EK K  A   +  +N+  +  D+F AG
Sbjct: 183  KLKMFVAHVIENHRRDWNPAEARDFIEAYLQEIEKHKGDATSSFQEENLICSTLDLFVAG 242

Query: 1130 TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPNRIPAIKDRLDMPYLDAVVHEIQRF 1309
            TETTSTTLR+GLL +  YPE++EK+  EIDRV+G  + P+   R  MPY +AV+HE+QR 
Sbjct: 243  TETTSTTLRWGLLYMALYPEIQEKVQAEIDRVLGQLQQPSTAARESMPYTNAVIHEVQRM 302

Query: 1310 IDLIPLHLP 1336
             ++IPL++P
Sbjct: 303  GNIIPLNVP 311


>ref|XP_003128010.2| PREDICTED: cytochrome P450 2J2-like [Sus scrofa].
          Length = 497

 Score =  260 bits (664), Expect = 1e-69
 Identities = 138/337 (40%), Positives = 206/337 (61%)
 Frame = +2

Query: 326  PPGPFPLPIVGNIFQLDLKNIPKSFTMLAERYGPVFTVYLGSRRIVVLHGYKAVKEVLLH 505
            PPGP  LP VGN   LD +    S     ++YG V ++ LG+   VV+ G   +KE L+H
Sbjct: 44   PPGPLRLPFVGNFLHLDFEQWHLSLQRFVKKYGNVLSLDLGAFSSVVITGLPLIKEALVH 103

Query: 506  YKNEFSGRGEIPTFQVHKDKGVIFNNGPTWRDTRRFSLTTLRDFGMGKQGNEQRIQREAH 685
                F  R  I   QV +  G+I +NG  W++ RRF+LTTLR+FG+GK+  E+RIQ EA 
Sbjct: 104  QDQNFVNR-PINLNQVFQKNGLIMSNGQVWKEQRRFALTTLRNFGLGKKSLEERIQEEAQ 162

Query: 686  FLLEALRKTHGQPFDPTFLIGCAPCNVISDILFRQHFDYNDKTCLRLMSMFNENFYLLST 865
            +L++A+R+ +G  FDP F I  A  N+I  I F + FDY D     L+ + +E   L  +
Sbjct: 163  YLIQAVREENGDLFDPHFKINNAVSNIICSITFGERFDYQDDQFQELLRLLDEVTCLPKS 222

Query: 866  GWIQLYNNFSGYLRYLPGSHRKLMKNISEIKDYALERVKDHRDSLEPSCPRDFTDTLLME 1045
              +QL+N F   ++ LPG H+ +  N  +++ +    +++HR    P+  RDF D  L E
Sbjct: 223  VRVQLFNVFPRIMKLLPGPHQIIFSNREKLRMFIARVIENHRRDWNPAEARDFIDAYLRE 282

Query: 1046 MEKEKYSAEPIYTLDNIAVTVADMFFAGTETTSTTLRYGLLILMKYPEVEEKLHEEIDRV 1225
            +EK   S+  ++  +N+  +  D+FFAGTETTSTTLR+GLL +  YPEV+E +  EIDRV
Sbjct: 283  IEKG--SSPSVFNEENLICSTLDLFFAGTETTSTTLRWGLLYMALYPEVQE-VQAEIDRV 339

Query: 1226 IGPNRIPAIKDRLDMPYLDAVVHEIQRFIDLIPLHLP 1336
            +G ++ P+   R  MPY +AV+HE+QR  ++IPL++P
Sbjct: 340  LGQSQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVP 376


  Database: RefSeq49_SP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 11,343,932
  Number of sequences in database:  24,897
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 24897
Number of Hits to DB: 30,258,833
Number of extensions: 1165928
Number of successful extensions: 2560
Number of sequences better than 1.0e-05: 36
Number of HSP's gapped: 2512
Number of HSP's successfully gapped: 38
Length of query: 445
Length of database: 11,343,932
Length adjustment: 102
Effective length of query: 343
Effective length of database: 8,804,438
Effective search space: 3019922234
Effective search space used: 3019922234
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)

BLASTN 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007014
         (1337 letters)

Database: Sscrofa_10.2.fasta 
           4582 sequences; 2,808,509,378 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Sscrofa_Chr14                                                         412   e-112

>Sscrofa_Chr14 
||          Length = 153851969

 Score =  412 bits (208), Expect = e-112
 Identities = 208/208 (100%)
 Strand = Plus / Plus

                                                                             
Query: 199       tccacacattgaaagatcccctgaaggagccatgactgccctgggcatcacggtggccct 258
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153478062 tccacacattgaaagatcccctgaaggagccatgactgccctgggcatcacggtggccct 153478121

                                                                             
Query: 259       gctggtgtggttggtcaccctgctgctcatctccatctggaagcacatccacagtagctg 318
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153478122 gctggtgtggttggtcaccctgctgctcatctccatctggaagcacatccacagtagctg 153478181

                                                                             
Query: 319       gaaacttccccctggccctttcccactgcccatcgttgggaacattttccagttggacct 378
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153478182 gaaacttccccctggccctttcccactgcccatcgttgggaacattttccagttggacct 153478241

                                             
Query: 379       taagaatattcccaaatccttcaccatg 406
                 ||||||||||||||||||||||||||||
Sbjct: 153478242 taagaatattcccaaatccttcaccatg 153478269



 Score =  357 bits (180), Expect = 1e-95
 Identities = 180/180 (100%)
 Strand = Plus / Plus

                                                                             
Query: 876       agctttataataatttctcaggctatctacgctacctgcctggaagccataggaaactaa 935
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153485202 agctttataataatttctcaggctatctacgctacctgcctggaagccataggaaactaa 153485261

                                                                             
Query: 936       tgaaaaatatatctgaaataaaagattatgctttagaaagagtgaaggaccaccgggatt 995
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153485262 tgaaaaatatatctgaaataaaagattatgctttagaaagagtgaaggaccaccgggatt 153485321

                                                                             
Query: 996       cactggagcccagctgtcctcgagatttcactgacaccctgctgatggaaatggagaagg 1055
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153485322 cactggagcccagctgtcctcgagatttcactgacaccctgctgatggaaatggagaagg 153485381



 Score =  321 bits (162), Expect = 6e-85
 Identities = 162/162 (100%)
 Strand = Plus / Plus

                                                                             
Query: 406       gctggcagagcgttacgggccggtgttcactgtgtacctgggttcgcggcgcattgtggt 465
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153479193 gctggcagagcgttacgggccggtgttcactgtgtacctgggttcgcggcgcattgtggt 153479252

                                                                             
Query: 466       cctgcacggctacaaggccgtgaaggaggtcttgctccactacaagaatgagttctctgg 525
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153479253 cctgcacggctacaaggccgtgaaggaggtcttgctccactacaagaatgagttctctgg 153479312

                                                           
Query: 526       cagaggggaaatccccacgttccaagtgcacaaggacaaagg 567
                 ||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153479313 cagaggggaaatccccacgttccaagtgcacaaggacaaagg 153479354



 Score =  313 bits (158), Expect = 1e-82
 Identities = 161/162 (99%)
 Strand = Plus / Plus

                                                                             
Query: 716       ggccagccctttgatcccaccttcctcatcggctgcgcaccctgcaatgtcatctccgac 775
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153483260 ggccagccctttgatcccaccttcctcatcggctgcgcaccctgcaatgtcatctccgac 153483319

                                                                             
Query: 776       atcctcttccgccagcactttgactacaatgacaagacctgtctgaggttaatgagcatg 835
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153483320 atcctcttccgccagcactttgactacaatgacaagacctgtctgaggttaatgagcatg 153483379

                                                           
Query: 836       ttcaatgagaacttctacctgctcagtaccggctggatccag 877
                 ||||||||||||||||||||||||||||| ||||||||||||
Sbjct: 153483380 ttcaatgagaacttctacctgctcagtactggctggatccag 153483421



 Score =  303 bits (153), Expect = 1e-79
 Identities = 153/153 (100%)
 Strand = Plus / Plus

                                                                             
Query: 565       aggggtcattttcaataatggaccaacctggcgggacactcggcggttctccctcaccac 624
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153482825 aggggtcattttcaataatggaccaacctggcgggacactcggcggttctccctcaccac 153482884

                                                                             
Query: 625       cctccgtgacttcgggatggggaaacagggcaatgagcagcggatccagagggaggccca 684
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153482885 cctccgtgacttcgggatggggaaacagggcaatgagcagcggatccagagggaggccca 153482944

                                                  
Query: 685       cttcctgctggaggcactcaggaagacccatgg 717
                 |||||||||||||||||||||||||||||||||
Sbjct: 153482945 cttcctgctggaggcactcaggaagacccatgg 153482977



 Score =  285 bits (144), Expect = 3e-74
 Identities = 144/144 (100%)
 Strand = Plus / Plus

                                                                             
Query: 1053      aggaaaaatacagtgcagaacctatatacaccttggacaacattgccgtgaccgtggccg 1112
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153486399 aggaaaaatacagtgcagaacctatatacaccttggacaacattgccgtgaccgtggccg 153486458

                                                                             
Query: 1113      acatgttctttgcggggacagagaccaccagcaccaccctgagatacgggctcctaattc 1172
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153486459 acatgttctttgcggggacagagaccaccagcaccaccctgagatacgggctcctaattc 153486518

                                         
Query: 1173      tcatgaaatacccagaggttgaag 1196
                 ||||||||||||||||||||||||
Sbjct: 153486519 tcatgaaatacccagaggttgaag 153486542



 Score =  260 bits (131), Expect = 2e-66
 Identities = 140/143 (97%)
 Strand = Plus / Plus

                                                                             
Query: 1195      agagaaacttcatgaagaaattgacagggtcattggtccaaacagaatccctgccatcaa 1254
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153488450 agagaaacttcatgaagaaattgacagggtcattggtccaaacagaatccctgccatcaa 153488509

                                                                             
Query: 1255      ggacaggctggacatgccctacctggatgccgtggtacatgagattcagcgattcatcga 1314
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 153488510 ggacaggctggacatgccctacctggatgccgtggtacatgagattcagcgattcatcga 153488569

                                        
Query: 1315      cctcattcccctccacctgccac 1337
                 ||||||||||  | |||||||||
Sbjct: 153488570 cctcattccctccaacctgccac 153488592


  Database: Sscrofa_10.2.fasta
    Posted date:  Nov 16, 2011 10:34 AM
  Number of letters in database: 2,808,509,378
  Number of sequences in database:  4582
  
Lambda     K      H
    1.37    0.711     1.31 

Gapped
Lambda     K      H
    1.37    0.711     1.31 


Matrix: blastn matrix:1 -3
Gap Penalties: Existence: 5, Extension: 2
Number of Sequences: 4582
Number of Hits to DB: 33,898,714
Number of extensions: 289
Number of successful extensions: 289
Number of sequences better than 1.0e-05: 1
Number of HSP's gapped: 289
Number of HSP's successfully gapped: 7
Length of query: 1337
Length of database: 2,808,509,378
Length adjustment: 21
Effective length of query: 1316
Effective length of database: 2,808,413,156
Effective search space: 3695871713296
Effective search space used: 3695871713296
X1: 11 (21.8 bits)
X2: 15 (29.7 bits)
X3: 50 (99.1 bits)
S1: 18 (36.2 bits)
S2: 30 (60.0 bits)