Animal-Genome cDNA 20110601C-007642

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007642
         (999 letters)

Database: RefSeq49_BP.fasta 
           33,088 sequences; 17,681,374 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_848669.1| macrophage-capping protein [Bos taurus].             538   e-153
Alignment   gi|NP_001106755.1| gelsolin isoform a [Bos taurus].                  258   4e-69
Alignment   gi|NP_001029799.1| gelsolin isoform b [Bos taurus].                  258   4e-69
Alignment   gi|NP_776602.1| adseverin [Bos taurus].                              258   6e-69
Alignment   gi|NP_001179458.1| advillin [Bos taurus].                            206   2e-53
Alignment   gi|XP_002687601.1| PREDICTED: advillin [Bos taurus].                 206   2e-53
Alignment   gi|NP_001013609.1| villin-1 [Bos taurus].                            203   2e-52
Alignment   gi|NP_001178050.2| villin-like [Bos taurus].                         164   1e-40
Alignment   gi|XP_002696989.1| PREDICTED: villin-like [Bos taurus].              164   1e-40
Alignment   gi|XP_002695913.1| PREDICTED: flightless-I homolog [Bos taurus].     132   4e-31

>ref|NP_848669.1| macrophage-capping protein [Bos taurus].
          Length = 349

 Score =  538 bits (1385), Expect = e-153
 Identities = 263/289 (91%), Positives = 272/289 (94%)
 Frame = +3

Query: 126 MYTSIPQSGSPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH 305
           MY+ IPQSGSPFP +V+ PGLHIWRVEKLKPVPVA EN GIFFSGDSYLVLHNGPEELSH
Sbjct: 1   MYSPIPQSGSPFPPTVKLPGLHIWRVEKLKPVPVAPENYGIFFSGDSYLVLHNGPEELSH 60

Query: 306 LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 485
           LHLWIG QSSRDEQG CA+LAVHLNTLLGERPVQHRE QGNESDLFMSYFP GLKYQEGG
Sbjct: 61  LHLWIGQQSSRDEQGGCAILAVHLNTLLGERPVQHRESQGNESDLFMSYFPHGLKYQEGG 120

Query: 486 VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 665
           VESAFHKTS G  PAAI+KLYQVKGKKNIRATER LSWDSFNTGDCFILDLGQNIFAWCG
Sbjct: 121 VESAFHKTSPGTAPAAIKKLYQVKGKKNIRATERVLSWDSFNTGDCFILDLGQNIFAWCG 180

Query: 666 AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL 845
           AKSNILERNKARDLALAIRDSERQGKA VEIVTDGEEPADMIQVLGPKP+LKEGNPEEDL
Sbjct: 181 AKSNILERNKARDLALAIRDSERQGKAHVEIVTDGEEPADMIQVLGPKPSLKEGNPEEDL 240

Query: 846 TADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           TAD+ NAQAAALYKVSDATGQMNL K+ADSSPFA+ELLIPDDCFVLD G
Sbjct: 241 TADRTNAQAAALYKVSDATGQMNLTKLADSSPFALELLIPDDCFVLDNG 289


>ref|NP_001106755.1| gelsolin isoform a [Bos taurus].
          Length = 781

 Score =  258 bits (660), Expect = 4e-69
 Identities = 134/278 (48%), Positives = 180/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL IWRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G++ S+
Sbjct: 63  KEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 121

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 122 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 181

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SW+SFN GDCFILDLG +I+ WCG+ SN  ER KA
Sbjct: 182 EV--VVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNDIYQWCGSSSNRFERLKA 239

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+A+V +  +G EP  M++VLGPKP L  G  E+    D  N + A 
Sbjct: 240 TQVSKGIRDNERSGRARVHVSEEGAEPEAMLEVLGPKPALPAGT-EDTAKEDAANRKLAK 298

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 299 LYKVSNGAGTMSVSLVADENPFAQGALRSEDCFILDHG 336



 Score =  103 bits (256), Expect = 3e-22
 Identities = 84/272 (30%), Positives = 121/272 (44%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
            IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 448  IWRIEGSDKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 507

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L   L+  LG  PVQ R VQG E    MS F  + +    GG          G T  A  
Sbjct: 508  LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYRGGT-----SREGGQTAPAST 562

Query: 540  KLYQVKGKKN--IRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
            +L+QV+   +   RA E      + N+ D F+L      + W GA ++  E+  A +L  
Sbjct: 563  RLFQVRASSSGATRAVEVMPKAGALNSNDAFVLKTPSAAYLWVGAGASEAEKTGALELLR 622

Query: 714  AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
             +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 623  VLR-------AQPVQVAEGSEPDSFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFACS 672

Query: 894  DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            +  G+  + +V        E L  DD  +LDT
Sbjct: 673  NKIGRFVIEEV--PGELMQEDLATDDVMLLDT 702


>ref|NP_001029799.1| gelsolin isoform b [Bos taurus].
          Length = 731

 Score =  258 bits (660), Expect = 4e-69
 Identities = 134/278 (48%), Positives = 180/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL IWRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G++ S+
Sbjct: 13  KEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 71

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 72  DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 131

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SW+SFN GDCFILDLG +I+ WCG+ SN  ER KA
Sbjct: 132 EV--VVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNDIYQWCGSSSNRFERLKA 189

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+A+V +  +G EP  M++VLGPKP L  G  E+    D  N + A 
Sbjct: 190 TQVSKGIRDNERSGRARVHVSEEGAEPEAMLEVLGPKPALPAGT-EDTAKEDAANRKLAK 248

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQGALRSEDCFILDHG 286



 Score =  101 bits (252), Expect = 9e-22
 Identities = 83/272 (30%), Positives = 121/272 (44%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
            IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 398  IWRIEGSDKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 457

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L   L+  LG  PV+ R VQG E    MS F  + +    GG          G T  A  
Sbjct: 458  LTAQLDEELGGTPVRSRVVQGKEPAHLMSLFGGKPMIIYRGGT-----SREGGQTAPAST 512

Query: 540  KLYQVKGKKN--IRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
            +L+QV+   +   RA E      + N+ D F+L      + W GA ++  E+  A +L  
Sbjct: 513  RLFQVRASSSGATRAVEVMPKAGALNSNDAFVLKTPSAAYLWVGAGASEAEKTGALELLR 572

Query: 714  AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
             +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 573  VLR-------AQPVQVAEGSEPDSFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFACS 622

Query: 894  DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            +  G+  + +V        E L  DD  +LDT
Sbjct: 623  NKIGRFVIEEV--PGELMQEDLATDDVMLLDT 652


>ref|NP_776602.1| adseverin [Bos taurus].
          Length = 715

 Score =  258 bits (659), Expect = 6e-69
 Identities = 126/274 (45%), Positives = 182/274 (66%), Gaps = 3/274 (1%)
 Frame = +3

Query: 183 GLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELS---HLHLWIGHQSSRDEQGA 353
           GL +WR+EKL+ VPV     G F+ GD+YLVLH           LH W+G + ++DE  A
Sbjct: 18  GLQVWRIEKLELVPVPESAYGNFYVGDAYLVLHTTQASRGFTYRLHFWLGKECTQDESTA 77

Query: 354 CAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSGATPAA 533
            A+  V ++  LG +PVQ+RE+QG ES  F+ YF  GLKY+ GGV S  +   +    A 
Sbjct: 78  AAIFTVQMDDYLGGKPVQNRELQGYESTDFVGYFKGGLKYKAGGVASGLNHVLTNDLTA- 136

Query: 534 IRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
            ++L  VKG++ +RATE  LSWDSFN GDCFI+DLG  I+ WCG+  N  ER KA  +A+
Sbjct: 137 -QRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKASQVAI 195

Query: 714 AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
            IRD+ER+G+AQ+ +V +G EP+++ +VLG KP L  G  ++D+ AD  N + A LY VS
Sbjct: 196 GIRDNERKGRAQLIVVEEGSEPSELTKVLGEKPKLTHGEDDDDIKADITNRKMAKLYMVS 255

Query: 894 DATGQMNLNKVADSSPFAVELLIPDDCFVLDTGS 995
           DA+G M ++ VA+ +PF++ +L+ ++CF+LD G+
Sbjct: 256 DASGSMKVSLVAEENPFSMAMLLSEECFILDHGA 289



 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 74/273 (27%), Positives = 114/273 (41%), Gaps = 6/273 (2%)
 Frame = +3

Query: 186  LHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSHLHLWIGHQSSRDEQGACAML 365
            + IWRVE    V + R + G F+ GD Y++L+  P     ++ W G  ++RDE       
Sbjct: 398  VQIWRVENNGRVEIDRNSYGEFYGGDCYIILYTYPRG-QIIYTWQGANATRDELTTSDSR 456

Query: 366  AVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIRK 542
                    G++ VQ R  QG E    +S F  + L   + G          G  PA   +
Sbjct: 457  LFSWIDPSGDQAVQIRVSQGKEPAHLLSLFKDKPLIIYKNGTSK-----KEGQAPAPPIR 511

Query: 543  LYQVKGKKNIRATERALSWD----SFNTGDCFILDLGQNI-FAWCGAKSNILERNKARDL 707
            L+QV  ++N+ +  R +  D    S N+ D F+L L QN  + W G  S   E   A  +
Sbjct: 512  LFQV--RRNLDSYTRIMEVDVDANSLNSNDVFVLKLRQNNGYIWIGKGSTQEEEKGAEYV 569

Query: 708  ALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYK 887
            A  +       K +   + +G+EP +    LG K   +       L   Q       LY 
Sbjct: 570  ASVL-------KCKTSTIQEGKEPEEFWNSLGGKKDYQ----TSPLLESQAEDHPPRLYG 618

Query: 888  VSDATGQMNLNKVADSSPFAVELLIPDDCFVLD 986
             S+ TG+  + +V     F  + L  DD  +LD
Sbjct: 619  CSNKTGRFIIEEV--PGEFTQDDLAEDDVMLLD 649


>ref|NP_001179458.1| advillin [Bos taurus].
          Length = 816

 Score =  206 bits (525), Expect = 2e-53
 Identities = 119/287 (41%), Positives = 166/287 (57%), Gaps = 9/287 (3%)
 Frame = +3

Query: 153 SPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIG 323
           S F A   DPG+  WR+EK++   V     G F+ GD Y++L     G      +H WIG
Sbjct: 5   SAFQAVGNDPGIITWRIEKMELALVPLSAHGNFYEGDCYVILSTRRVGCLLSQDIHFWIG 64

Query: 324 HQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFH 503
             SS+DEQ   A+    L+  LG  PVQHREVQ +ESD F  YF +G+ Y++GGV S   
Sbjct: 65  KDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMK 124

Query: 504 KTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNIL 683
              + A    +++L  VKGK+NIRATE  +SWDSFN GD F+LDLG+ I  W G +S+  
Sbjct: 125 HVETNAYN--VKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIVQWNGPESSSG 182

Query: 684 ERNKARDLALAIRDSERQGKAQVEIVTDGEEPAD------MIQVLGPKPTLKEGNPEEDL 845
           ER KA  LA  IRD ER G+A++ ++   +E A       +   LG +  ++   P+E  
Sbjct: 183 ERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIQPAVPDE-- 240

Query: 846 TADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLD 986
             DQ+      LY VSD++GQ+ + +VA + P   +LL PDDC++LD
Sbjct: 241 VIDQQQKSNITLYHVSDSSGQLVVTEVA-TRPLVQDLLNPDDCYILD 286



 Score =  108 bits (271), Expect = 6e-24
 Identities = 85/276 (30%), Positives = 130/276 (47%), Gaps = 8/276 (2%)
 Frame = +3

Query: 186  LHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSRDEQG 350
            + +WR+E L+ VPV  +  G F+ GD YLVL     H  P  +  L++W G  +S+DE  
Sbjct: 397  VEVWRIENLELVPVEHQWYGFFYGGDCYLVLYTYEMHGKPHYI--LYIWQGCHASQDELA 454

Query: 351  ACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSGATPA 530
            A A  AV ++      PVQ R   G E   FM+ F   L   EGG           A P 
Sbjct: 455  ASAYQAVEVDQQFEGAPVQVRVTMGKEPRHFMAIFKGKLVIFEGGT-----SRKGNAEPD 509

Query: 531  AIRKLYQVKG--KKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARD 704
               +L+Q++G  K N +A E      S N+ D F+L      + W G  S+  ER  A++
Sbjct: 510  PPVRLFQIQGHNKSNTKAVEVPAFTSSLNSNDVFLLRTQAEHYLWFGKGSSGDERAMAKE 569

Query: 705  LALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPK-PTLKEGNPEEDLTADQKNAQAAAL 881
            LA  + D           V +G+EPA+   +LG K P   +   ++++   Q     + L
Sbjct: 570  LAGLLCDGTE------NTVAEGQEPAEFWDLLGGKTPYASDKRLQQEILDVQ-----SRL 618

Query: 882  YKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            ++ S+ TG+  + ++ D   F  + L P D  +LDT
Sbjct: 619  FECSNKTGRFTVTEIID---FTQDDLNPGDVMLLDT 651


>ref|XP_002687601.1| PREDICTED: advillin [Bos taurus].
          Length = 816

 Score =  206 bits (525), Expect = 2e-53
 Identities = 119/287 (41%), Positives = 166/287 (57%), Gaps = 9/287 (3%)
 Frame = +3

Query: 153 SPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIG 323
           S F A   DPG+  WR+EK++   V     G F+ GD Y++L     G      +H WIG
Sbjct: 5   SAFQAVGNDPGIITWRIEKMELALVPLSAHGNFYEGDCYVILSTRRVGCLLSQDIHFWIG 64

Query: 324 HQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFH 503
             SS+DEQ   A+    L+  LG  PVQHREVQ +ESD F  YF +G+ Y++GGV S   
Sbjct: 65  KDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMK 124

Query: 504 KTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNIL 683
              + A    +++L  VKGK+NIRATE  +SWDSFN GD F+LDLG+ I  W G +S+  
Sbjct: 125 HVETNAYN--VKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIVQWNGPESSSG 182

Query: 684 ERNKARDLALAIRDSERQGKAQVEIVTDGEEPAD------MIQVLGPKPTLKEGNPEEDL 845
           ER KA  LA  IRD ER G+A++ ++   +E A       +   LG +  ++   P+E  
Sbjct: 183 ERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIQPAVPDE-- 240

Query: 846 TADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLD 986
             DQ+      LY VSD++GQ+ + +VA + P   +LL PDDC++LD
Sbjct: 241 VIDQQQKSNITLYHVSDSSGQLVVTEVA-TRPLVQDLLNPDDCYILD 286



 Score =  108 bits (271), Expect = 6e-24
 Identities = 85/276 (30%), Positives = 130/276 (47%), Gaps = 8/276 (2%)
 Frame = +3

Query: 186  LHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSRDEQG 350
            + +WR+E L+ VPV  +  G F+ GD YLVL     H  P  +  L++W G  +S+DE  
Sbjct: 397  VEVWRIENLELVPVEHQWYGFFYGGDCYLVLYTYEMHGKPHYI--LYIWQGCHASQDELA 454

Query: 351  ACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSGATPA 530
            A A  AV ++      PVQ R   G E   FM+ F   L   EGG           A P 
Sbjct: 455  ASAYQAVEVDQQFEGAPVQVRVTMGKEPRHFMAIFKGKLVIFEGGT-----SRKGNAEPD 509

Query: 531  AIRKLYQVKG--KKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARD 704
               +L+Q++G  K N +A E      S N+ D F+L      + W G  S+  ER  A++
Sbjct: 510  PPVRLFQIQGHNKSNTKAVEVPAFTSSLNSNDVFLLRTQAEHYLWFGKGSSGDERAMAKE 569

Query: 705  LALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPK-PTLKEGNPEEDLTADQKNAQAAAL 881
            LA  + D           V +G+EPA+   +LG K P   +   ++++   Q     + L
Sbjct: 570  LAGLLCDGTE------NTVAEGQEPAEFWDLLGGKTPYASDKRLQQEILDVQ-----SRL 618

Query: 882  YKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            ++ S+ TG+  + ++ D   F  + L P D  +LDT
Sbjct: 619  FECSNKTGRFTVTEIID---FTQDDLNPGDVMLLDT 651


>ref|NP_001013609.1| villin-1 [Bos taurus].
          Length = 827

 Score =  203 bits (516), Expect = 2e-52
 Identities = 116/286 (40%), Positives = 166/286 (58%), Gaps = 9/286 (3%)
 Frame = +3

Query: 168 SVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL--HNGPEELSH-LHLWIGHQSSR 338
           ++  PG+ IWR+E ++ VPV   + G FF GD Y++L  H     LS+ +H WIG  SS+
Sbjct: 13  NITTPGVQIWRIEAMQMVPVPSNSFGSFFDGDCYVILAIHKTGSNLSYDIHYWIGQASSQ 72

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DEQGA A+    ++  L  R VQHREVQGNESD F  YF +G+  ++GGV S   +  + 
Sbjct: 73  DEQGAAAIYTTQMDDFLKGRAVQHREVQGNESDTFRGYFKKGIVIRKGGVASGMKQVETN 132

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
           +    I++L  VKGK+N+ A E  +SW SFN GD F+LDLG+ I  W G +SN +ER + 
Sbjct: 133 SYD--IQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESNHMERLRG 190

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPAD------MIQVLGPKPTLKEGNPEEDLTADQK 860
            +LA  IRD ER G+  V +V   +E A       M  VLG +  LK      D   +  
Sbjct: 191 MNLAKEIRDQERGGRTYVGVVDGEDEKASPQLMEIMNHVLGQRKELKAA--VADTVVEPA 248

Query: 861 NAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTGSV 998
              A  LY VSD+ G++ + ++A + P   +LL  +DC++LD G +
Sbjct: 249 LKAALKLYHVSDSEGKVVVREIA-TQPLTQDLLSHEDCYILDQGGL 293



 Score =  104 bits (259), Expect = 1e-22
 Identities = 87/274 (31%), Positives = 129/274 (47%), Gaps = 7/274 (2%)
 Frame = +3

Query: 186  LHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNG-PEELSH--LHLWIGHQSSRDEQGAC 356
            + +WR+E L+ VPV  +  G FF GD YL+L+     E  H  L++W G Q+S+DE  A 
Sbjct: 400  VQMWRIENLELVPVNTKWLGHFFGGDCYLLLYTYFINEKPHYLLYIWQGSQASQDEITAS 459

Query: 357  AMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSGATPAAI 536
            A  AV L+      PVQ R   G E    MS F   +   +GG   A     +   P   
Sbjct: 460  AYQAVILDQEYNNEPVQIRVPMGKEPPHLMSIFKGCMVVYQGGTSRA-----NSVEPVPS 514

Query: 537  RKLYQVKG--KKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLA 710
             +L+QV+G    N +A E +    S N+ D FIL      + WCG   +  ER  A+ +A
Sbjct: 515  TRLFQVRGTSANNTKAFEVSPRAASLNSNDVFILKTQSCCYLWCGKGCSGDEREMAKMVA 574

Query: 711  LAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGN--PEEDLTADQKNAQAAALY 884
              +  +E+Q      +V +G+EPA+    LG K          EE+L    +      L+
Sbjct: 575  DTVSRTEKQ------VVVEGQEPANFWLALGGKAPYASTKRLQEENLVITPR------LF 622

Query: 885  KVSDATGQMNLNKVADSSPFAVELLIPDDCFVLD 986
            + S+ TG+    ++ D   F  + L  DD F+LD
Sbjct: 623  ECSNQTGRFLATEIPD---FNQDDLEEDDVFLLD 653


>ref|NP_001178050.2| villin-like [Bos taurus].
          Length = 889

 Score =  164 bits (415), Expect = 1e-40
 Identities = 97/279 (34%), Positives = 151/279 (54%), Gaps = 10/279 (3%)
 Frame = +3

Query: 186 LHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELS-------HLHLWIGHQSSRDE 344
           LHIW +E L+ VPV     G FF    Y+VLH  P+ L         LH W+G  ++   
Sbjct: 39  LHIWIIENLQMVPVPEPAYGNFFEKHCYVVLHV-PQSLKATPGVPKDLHYWVGKMAAPGA 97

Query: 345 QGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSGAT 524
           QGA      HL   LG   VQHREVQG+ES  F SYF  G+ Y++GG+ SA     +   
Sbjct: 98  QGAPGSFLQHLKEALGGATVQHREVQGHESACFRSYFRSGIIYRKGGLASALKHVETNVY 157

Query: 525 PAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARD 704
              I++L +++G K++ ATE  LSW SFN  D F+LDLG+ +  W G K++   + +   
Sbjct: 158 N--IQRLLRIRGGKHVSATEVELSWHSFNNSDVFLLDLGRMMIQWNGPKASAARKARGLF 215

Query: 705 LALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA-- 878
           L  ++RD ER G+AQV +V D  E  D+++++      + G+    + + + N    A  
Sbjct: 216 LTHSLRDRERGGRAQVSVVDDEAEATDLMEIMEAVLGRRVGSLHAAMPSKRMNQLQKANV 275

Query: 879 -LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
            LY+V   +  + + +++ + P   +LL  ++C++LD G
Sbjct: 276 HLYQVCQKSKDLVVQELS-TCPLTQDLLQEENCYILDQG 313



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 69/273 (25%), Positives = 109/273 (39%), Gaps = 6/273 (2%)
 Frame = +3

Query: 186  LHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEE--LSH-LHLWIGHQSSRDEQGAC 356
            + IW ++     PV  +  G   +   YLVL+       + H L+LW G Q++  E  A 
Sbjct: 417  VQIWCIQDSHRQPVDPKRHGQLCADSCYLVLYTYRRMGFVQHVLYLWQGLQATAHEISAL 476

Query: 357  AMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSGATPAAI 536
               A  L+       VQ     G+E   F++ F   L   +G       + S    PA  
Sbjct: 477  RGNAEELDLWYRGALVQEHVTMGSEPPHFLAIFQGQLVIFQG-----HPRHSRKGQPAPA 531

Query: 537  RKLYQVKG--KKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLA 710
              L+ ++G    N R  E      + N+ D F+L      + W G   +  +R  AR + 
Sbjct: 532  VSLFHIQGTDSYNTRTMEVPARASALNSSDVFLLVTANLCYLWFGKGCSGDQREMARTVV 591

Query: 711  LAIRDSERQGKAQVEIVTDGEEPADMIQVLGPK-PTLKEGNPEEDLTADQKNAQAAALYK 887
              I       +  +EIV +G+EP +  + LG + P      P ED+   Q       L++
Sbjct: 592  TII------CREDMEIVLEGQEPPNFWEALGGRAPYRSNKRPPEDVCDFQPR-----LFE 640

Query: 888  VSDATGQMNLNKVADSSPFAVELLIPDDCFVLD 986
             S   G + L +V     F+ E L   D  +LD
Sbjct: 641  CSCQAGPLVLTEVVF---FSQEDLDKYDVMLLD 670


>ref|XP_002696989.1| PREDICTED: villin-like [Bos taurus].
          Length = 889

 Score =  164 bits (415), Expect = 1e-40
 Identities = 97/279 (34%), Positives = 151/279 (54%), Gaps = 10/279 (3%)
 Frame = +3

Query: 186 LHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELS-------HLHLWIGHQSSRDE 344
           LHIW +E L+ VPV     G FF    Y+VLH  P+ L         LH W+G  ++   
Sbjct: 39  LHIWIIENLQMVPVPEPAYGNFFEKHCYVVLHV-PQSLKATPGVPKDLHYWVGKMAAPGA 97

Query: 345 QGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSGAT 524
           QGA      HL   LG   VQHREVQG+ES  F SYF  G+ Y++GG+ SA     +   
Sbjct: 98  QGAPGSFLQHLKEALGGATVQHREVQGHESACFRSYFRSGIIYRKGGLASALKHVETNVY 157

Query: 525 PAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARD 704
              I++L +++G K++ ATE  LSW SFN  D F+LDLG+ +  W G K++   + +   
Sbjct: 158 N--IQRLLRIRGGKHVSATEVELSWHSFNNSDVFLLDLGRMMIQWNGPKASAARKARGLF 215

Query: 705 LALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA-- 878
           L  ++RD ER G+AQV +V D  E  D+++++      + G+    + + + N    A  
Sbjct: 216 LTHSLRDRERGGRAQVSVVDDEAEATDLMEIMEAVLGRRVGSLHAAMPSKRMNQLQKANV 275

Query: 879 -LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
            LY+V   +  + + +++ + P   +LL  ++C++LD G
Sbjct: 276 HLYQVCQKSKDLVVQELS-TCPLTQDLLQEENCYILDQG 313



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 69/273 (25%), Positives = 109/273 (39%), Gaps = 6/273 (2%)
 Frame = +3

Query: 186  LHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEE--LSH-LHLWIGHQSSRDEQGAC 356
            + IW ++     PV  +  G   +   YLVL+       + H L+LW G Q++  E  A 
Sbjct: 417  VQIWCIQDSHRQPVDPKRHGQLCADSCYLVLYTYRRMGFVQHVLYLWQGLQATAHEISAL 476

Query: 357  AMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSGATPAAI 536
               A  L+       VQ     G+E   F++ F   L   +G       + S    PA  
Sbjct: 477  RGNAEELDLWYRGALVQEHVTMGSEPPHFLAIFQGQLVIFQG-----HPRHSRKGQPAPA 531

Query: 537  RKLYQVKG--KKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLA 710
              L+ ++G    N R  E      + N+ D F+L      + W G   +  +R  AR + 
Sbjct: 532  VSLFHIQGTDSYNTRTMEVPARASALNSSDVFLLVTANLCYLWFGKGCSGDQREMARTVV 591

Query: 711  LAIRDSERQGKAQVEIVTDGEEPADMIQVLGPK-PTLKEGNPEEDLTADQKNAQAAALYK 887
              I       +  +EIV +G+EP +  + LG + P      P ED+   Q       L++
Sbjct: 592  TII------CREDMEIVLEGQEPPNFWEALGGRAPYRSNKRPPEDVCDFQPR-----LFE 640

Query: 888  VSDATGQMNLNKVADSSPFAVELLIPDDCFVLD 986
             S   G + L +V     F+ E L   D  +LD
Sbjct: 641  CSCQAGPLVLTEVVF---FSQEDLDKYDVMLLD 670


>ref|XP_002695913.1| PREDICTED: flightless-I homolog [Bos taurus].
          Length = 1283

 Score =  132 bits (333), Expect = 4e-31
 Identities = 81/255 (31%), Positives = 130/255 (50%), Gaps = 4/255 (1%)
 Frame = +3

Query: 174  QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSHL----HLWIGHQSSRD 341
            Q PGL IW++E   PV V  +  G F+  D Y+VL    ++   L    + WIG +++ D
Sbjct: 512  QLPGLTIWQIENFVPVLVEEDLHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLD 571

Query: 342  EQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSGA 521
            ++   A+ AV+L   LG      RE  G+ES+ F+  F   + Y EGG  S F+      
Sbjct: 572  KKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVED-- 629

Query: 522  TPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKAR 701
                + ++Y+V GKKNI+     L   S +    F+LD G +I+ W GA++ +    KAR
Sbjct: 630  -THYVTRMYRVYGKKNIKLEPVPLKGASLDPRFVFLLDRGLDIYVWRGAQATLSSTTKAR 688

Query: 702  DLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAAL 881
              A  I  +ER+GKA++ ++  G+EP +  + LG +P+  + +  +D    Q       L
Sbjct: 689  LFAEKINKNERKGKAEISLLVQGQEPPEFWETLGGEPSEIKKHVPDDFWPPQPK-----L 743

Query: 882  YKVSDATGQMNLNKV 926
            YKV    G + L ++
Sbjct: 744  YKVGLGLGYLELPQI 758


  Database: RefSeq49_BP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 17,681,374
  Number of sequences in database:  33,088
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33088
Number of Hits to DB: 42,947,107
Number of extensions: 1350619
Number of successful extensions: 6435
Number of sequences better than 1.0e-05: 11
Number of HSP's gapped: 6343
Number of HSP's successfully gapped: 19
Length of query: 333
Length of database: 17,681,374
Length adjustment: 103
Effective length of query: 230
Effective length of database: 14,273,310
Effective search space: 3282861300
Effective search space used: 3282861300
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 34 (17.7 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007642
         (999 letters)

Database: RefSeq49_CP.fasta 
           33,336 sequences; 18,874,504 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|XP_540197.2| PREDICTED: similar to Macrophage capping protei...   544   e-155
Alignment   gi|XP_867892.1| PREDICTED: similar to Gelsolin precursor (Actin...   261   6e-70
Alignment   gi|XP_867885.1| PREDICTED: similar to Gelsolin precursor (Actin...   261   6e-70
Alignment   gi|XP_867879.1| PREDICTED: similar to Gelsolin precursor (Actin...   261   6e-70
Alignment   gi|XP_867872.1| PREDICTED: similar to Gelsolin precursor (Actin...   261   6e-70
Alignment   gi|XP_867855.1| PREDICTED: similar to Gelsolin precursor (Actin...   261   6e-70
Alignment   gi|XP_867849.1| PREDICTED: similar to Gelsolin precursor (Actin...   261   6e-70
Alignment   gi|XP_853737.1| PREDICTED: similar to Gelsolin precursor (Actin...   261   6e-70
Alignment   gi|XP_532049.2| PREDICTED: similar to Gelsolin precursor (Actin...   235   4e-62
Alignment   gi|XP_532479.2| PREDICTED: similar to Adseverin (Scinderin) [Ca...   215   5e-56

>ref|XP_540197.2| PREDICTED: similar to Macrophage capping protein (Actin-regulatory
           protein CAP-G) [Canis familiaris].
          Length = 349

 Score =  544 bits (1401), Expect = e-155
 Identities = 263/289 (91%), Positives = 275/289 (95%)
 Frame = +3

Query: 126 MYTSIPQSGSPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH 305
           MYTS+PQ GSPFP SVQDPGLH+WRVEKLKPVPVARENQG+FFSGDSYLVLHNGPEELSH
Sbjct: 1   MYTSLPQGGSPFPGSVQDPGLHVWRVEKLKPVPVARENQGVFFSGDSYLVLHNGPEELSH 60

Query: 306 LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 485
           LHLWIG QSSRDEQGACA+LAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG
Sbjct: 61  LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120

Query: 486 VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 665
           VESAFHKTS GAT A I+KLYQVKGKKNIRATERAL+WD+FNTG+CFILDLG NIF WCG
Sbjct: 121 VESAFHKTSPGATAAPIKKLYQVKGKKNIRATERALNWDNFNTGECFILDLGPNIFTWCG 180

Query: 666 AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL 845
            KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPA+MIQVLGPKP LKEGNPEEDL
Sbjct: 181 GKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDL 240

Query: 846 TADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           TAD+ NAQAAALYKVSDATGQMNL KVADSSPFA+ELL+ DDCFVLD G
Sbjct: 241 TADRTNAQAAALYKVSDATGQMNLTKVADSSPFALELLLSDDCFVLDNG 289


>ref|XP_867892.1| PREDICTED: similar to Gelsolin precursor (Actin-depolymerizing
           factor) (ADF) (Brevin) (AGEL) isoform 8 [Canis
           familiaris].
          Length = 743

 Score =  261 bits (668), Expect = 6e-70
 Identities = 136/278 (48%), Positives = 179/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL +WRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G + S+
Sbjct: 24  KEPGLQVWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGKECSQ 82

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 83  DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 142

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SWDSFN GDCFILDLG NI+ WCG+ SN  E+ KA
Sbjct: 143 EV--VVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSNSNRYEKLKA 200

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+AQV +  +G EP  M+QVLGPKP L  G  E+    D  N + A 
Sbjct: 201 TQVSKGIRDNERSGRAQVHVSEEGAEPEAMLQVLGPKPALPAG-AEDTAKEDAANRKLAK 259

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 260 LYKVSNGAGTMSVSLVADENPFAQGALRSEDCFILDHG 297



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 78/273 (28%), Positives = 115/273 (42%), Gaps = 7/273 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARE--NQGIFFSGDSYLVLHNGPEELSHLHLWI--GHQSSRDEQGACA 359
            +WR      VP++      G FF    YL++H    E          G QS++DE  A A
Sbjct: 409  VWRPRTSNRVPMSPHLATSGFFFFLRFYLLIHERHRERQRPRQREKQGAQSTQDEVAASA 468

Query: 360  MLAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAI 536
            +L   L+  LG  PVQ R VQG E    MS F  + +   +GG          G T  A 
Sbjct: 469  ILTAQLDEELGGSPVQSRVVQGKEPAHLMSLFGGKPMIVYKGGT-----SRDGGQTAPAS 523

Query: 537  RKLYQVKGKKN--IRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLA 710
             +L+QV+   +   RA E      + N+ D F+L      + W GA ++  E++ A++L 
Sbjct: 524  TRLFQVRASSSGATRAVEIMPKAGALNSNDAFVLKTPSAAYLWVGAGASEAEKSGAQELL 583

Query: 711  LAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKV 890
              +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  
Sbjct: 584  RVLR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFAC 633

Query: 891  SDATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            S+  G+  + +V        E L  DD  +LDT
Sbjct: 634  SNKIGRFVIEEV--PGELMQEDLATDDVMLLDT 664


>ref|XP_867885.1| PREDICTED: similar to Gelsolin precursor (Actin-depolymerizing
           factor) (ADF) (Brevin) (AGEL) isoform 7 [Canis
           familiaris].
          Length = 732

 Score =  261 bits (668), Expect = 6e-70
 Identities = 136/278 (48%), Positives = 179/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL +WRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G + S+
Sbjct: 13  KEPGLQVWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGKECSQ 71

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 72  DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 131

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SWDSFN GDCFILDLG NI+ WCG+ SN  E+ KA
Sbjct: 132 EV--VVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSNSNRYEKLKA 189

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+AQV +  +G EP  M+QVLGPKP L  G  E+    D  N + A 
Sbjct: 190 TQVSKGIRDNERSGRAQVHVSEEGAEPEAMLQVLGPKPALPAG-AEDTAKEDAANRKLAK 248

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQGALRSEDCFILDHG 286



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 78/273 (28%), Positives = 115/273 (42%), Gaps = 7/273 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARE--NQGIFFSGDSYLVLHNGPEELSHLHLWI--GHQSSRDEQGACA 359
            +WR      VP++      G FF    YL++H    E          G QS++DE  A A
Sbjct: 398  VWRPRTSNRVPMSPHLATSGFFFFLRFYLLIHERHRERQRPRQREKQGAQSTQDEVAASA 457

Query: 360  MLAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAI 536
            +L   L+  LG  PVQ R VQG E    MS F  + +   +GG          G T  A 
Sbjct: 458  ILTAQLDEELGGSPVQSRVVQGKEPAHLMSLFGGKPMIVYKGGT-----SRDGGQTAPAS 512

Query: 537  RKLYQVKGKKN--IRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLA 710
             +L+QV+   +   RA E      + N+ D F+L      + W GA ++  E++ A++L 
Sbjct: 513  TRLFQVRASSSGATRAVEIMPKAGALNSNDAFVLKTPSAAYLWVGAGASEAEKSGAQELL 572

Query: 711  LAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKV 890
              +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  
Sbjct: 573  RVLR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFAC 622

Query: 891  SDATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            S+  G+  + +V        E L  DD  +LDT
Sbjct: 623  SNKIGRFVIEEV--PGELMQEDLATDDVMLLDT 653


>ref|XP_867879.1| PREDICTED: similar to Gelsolin precursor (Actin-depolymerizing
           factor) (ADF) (Brevin) (AGEL) isoform 6 [Canis
           familiaris].
          Length = 768

 Score =  261 bits (668), Expect = 6e-70
 Identities = 136/278 (48%), Positives = 179/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL +WRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G + S+
Sbjct: 62  KEPGLQVWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGKECSQ 120

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 121 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 180

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SWDSFN GDCFILDLG NI+ WCG+ SN  E+ KA
Sbjct: 181 EV--VVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSNSNRYEKLKA 238

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+AQV +  +G EP  M+QVLGPKP L  G  E+    D  N + A 
Sbjct: 239 TQVSKGIRDNERSGRAQVHVSEEGAEPEAMLQVLGPKPALPAG-AEDTAKEDAANRKLAK 297

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 298 LYKVSNGAGTMSVSLVADENPFAQGALRSEDCFILDHG 335



 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 70/238 (29%), Positives = 102/238 (42%), Gaps = 3/238 (1%)
 Frame = +3

Query: 285  GPEELSHLHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYF-PR 461
            G   L     W G QS++DE  A A+L   L+  LG  PVQ R VQG E    MS F  +
Sbjct: 469  GGRRLRSTSRWQGAQSTQDEVAASAILTAQLDEELGGSPVQSRVVQGKEPAHLMSLFGGK 528

Query: 462  GLKYQEGGVESAFHKTSSGATPAAIRKLYQVKGKKN--IRATERALSWDSFNTGDCFILD 635
             +   +GG          G T  A  +L+QV+   +   RA E      + N+ D F+L 
Sbjct: 529  PMIVYKGGT-----SRDGGQTAPASTRLFQVRASSSGATRAVEIMPKAGALNSNDAFVLK 583

Query: 636  LGQNIFAWCGAKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPT 815
                 + W GA ++  E++ A++L   +R       AQ   V +G EP    + LG K  
Sbjct: 584  TPSAAYLWVGAGASEAEKSGAQELLRVLR-------AQPVQVAEGSEPDGFWEALGGKAA 636

Query: 816  LKEGNPEEDLTADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
             +     +D   D   A    L+  S+  G+  + +V        E L  DD  +LDT
Sbjct: 637  YRTSPRLKDKKMD---AHPPRLFACSNKIGRFVIEEV--PGELMQEDLATDDVMLLDT 689


>ref|XP_867872.1| PREDICTED: similar to Gelsolin precursor (Actin-depolymerizing
           factor) (ADF) (Brevin) (AGEL) isoform 5 [Canis
           familiaris].
          Length = 781

 Score =  261 bits (668), Expect = 6e-70
 Identities = 136/278 (48%), Positives = 179/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL +WRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G + S+
Sbjct: 62  KEPGLQVWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGKECSQ 120

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 121 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 180

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SWDSFN GDCFILDLG NI+ WCG+ SN  E+ KA
Sbjct: 181 EV--VVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSNSNRYEKLKA 238

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+AQV +  +G EP  M+QVLGPKP L  G  E+    D  N + A 
Sbjct: 239 TQVSKGIRDNERSGRAQVHVSEEGAEPEAMLQVLGPKPALPAG-AEDTAKEDAANRKLAK 297

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 298 LYKVSNGAGTMSVSLVADENPFAQGALRSEDCFILDHG 335



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 74/254 (29%), Positives = 108/254 (42%), Gaps = 5/254 (1%)
 Frame = +3

Query: 243  GIFFSGDSYLVLHNGPEELSHLHLWI--GHQSSRDEQGACAMLAVHLNTLLGERPVQHRE 416
            G FF    YL++H    E          G QS++DE  A A+L   L+  LG  PVQ R 
Sbjct: 466  GFFFFLRFYLLIHERHRERQRPRQREKQGAQSTQDEVAASAILTAQLDEELGGSPVQSRV 525

Query: 417  VQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIRKLYQVKGKKN--IRATER 587
            VQG E    MS F  + +   +GG          G T  A  +L+QV+   +   RA E 
Sbjct: 526  VQGKEPAHLMSLFGGKPMIVYKGGT-----SRDGGQTAPASTRLFQVRASSSGATRAVEI 580

Query: 588  ALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLALAIRDSERQGKAQVEIVTD 767
                 + N+ D F+L      + W GA ++  E++ A++L   +R       AQ   V +
Sbjct: 581  MPKAGALNSNDAFVLKTPSAAYLWVGAGASEAEKSGAQELLRVLR-------AQPVQVAE 633

Query: 768  GEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVSDATGQMNLNKVADSSPFA 947
            G EP    + LG K   +     +D   D   A    L+  S+  G+  + +V       
Sbjct: 634  GSEPDGFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFACSNKIGRFVIEEV--PGELM 688

Query: 948  VELLIPDDCFVLDT 989
             E L  DD  +LDT
Sbjct: 689  QEDLATDDVMLLDT 702


>ref|XP_867855.1| PREDICTED: similar to Gelsolin precursor (Actin-depolymerizing
           factor) (ADF) (Brevin) (AGEL) isoform 4 [Canis
           familiaris].
          Length = 762

 Score =  261 bits (668), Expect = 6e-70
 Identities = 136/278 (48%), Positives = 179/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL +WRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G + S+
Sbjct: 62  KEPGLQVWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGKECSQ 120

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 121 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 180

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SWDSFN GDCFILDLG NI+ WCG+ SN  E+ KA
Sbjct: 181 EV--VVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSNSNRYEKLKA 238

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+AQV +  +G EP  M+QVLGPKP L  G  E+    D  N + A 
Sbjct: 239 TQVSKGIRDNERSGRAQVHVSEEGAEPEAMLQVLGPKPALPAG-AEDTAKEDAANRKLAK 297

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 298 LYKVSNGAGTMSVSLVADENPFAQGALRSEDCFILDHG 335



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 78/273 (28%), Positives = 115/273 (42%), Gaps = 7/273 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARE--NQGIFFSGDSYLVLHNGPEELSHLHLWI--GHQSSRDEQGACA 359
            +WR      VP++      G FF    YL++H    E          G QS++DE  A A
Sbjct: 447  VWRPRTSNRVPMSPHLATSGFFFFLRFYLLIHERHRERQRPRQREKQGAQSTQDEVAASA 506

Query: 360  MLAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAI 536
            +L   L+  LG  PVQ R VQG E    MS F  + +   +GG          G T  A 
Sbjct: 507  ILTAQLDEELGGSPVQSRVVQGKEPAHLMSLFGGKPMIVYKGGT-----SRDGGQTAPAS 561

Query: 537  RKLYQVKGKKN--IRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLA 710
             +L+QV+   +   RA E      + N+ D F+L      + W GA ++  E++ A++L 
Sbjct: 562  TRLFQVRASSSGATRAVEIMPKAGALNSNDAFVLKTPSAAYLWVGAGASEAEKSGAQELL 621

Query: 711  LAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKV 890
              +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  
Sbjct: 622  RVLR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFAC 671

Query: 891  SDATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            S+  G+  + +V        E L  DD  +LDT
Sbjct: 672  SNKIGRFVIEEV--PGELMQEDLATDDVMLLDT 702


>ref|XP_867849.1| PREDICTED: similar to Gelsolin precursor (Actin-depolymerizing
           factor) (ADF) (Brevin) (AGEL) isoform 3 [Canis
           familiaris].
          Length = 782

 Score =  261 bits (668), Expect = 6e-70
 Identities = 136/278 (48%), Positives = 179/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL +WRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G + S+
Sbjct: 62  KEPGLQVWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGKECSQ 120

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 121 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 180

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SWDSFN GDCFILDLG NI+ WCG+ SN  E+ KA
Sbjct: 181 EV--VVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSNSNRYEKLKA 238

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+AQV +  +G EP  M+QVLGPKP L  G  E+    D  N + A 
Sbjct: 239 TQVSKGIRDNERSGRAQVHVSEEGAEPEAMLQVLGPKPALPAG-AEDTAKEDAANRKLAK 297

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 298 LYKVSNGAGTMSVSLVADENPFAQGALRSEDCFILDHG 335



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 70/239 (29%), Positives = 104/239 (43%), Gaps = 3/239 (1%)
 Frame = +3

Query: 282  NGPEELSHLHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYF-P 458
            +G  E     +W G QS++DE  A A+L   L+  LG  PVQ R VQG E    MS F  
Sbjct: 482  SGDREAFIFRVWQGAQSTQDEVAASAILTAQLDEELGGSPVQSRVVQGKEPAHLMSLFGG 541

Query: 459  RGLKYQEGGVESAFHKTSSGATPAAIRKLYQVKGKKN--IRATERALSWDSFNTGDCFIL 632
            + +   +GG          G T  A  +L+QV+   +   RA E      + N+ D F+L
Sbjct: 542  KPMIVYKGGT-----SRDGGQTAPASTRLFQVRASSSGATRAVEIMPKAGALNSNDAFVL 596

Query: 633  DLGQNIFAWCGAKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKP 812
                  + W GA ++  E++ A++L   +R       AQ   V +G EP    + LG K 
Sbjct: 597  KTPSAAYLWVGAGASEAEKSGAQELLRVLR-------AQPVQVAEGSEPDGFWEALGGKA 649

Query: 813  TLKEGNPEEDLTADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
              +     +D   D   A    L+  S+  G+  + +V        E L  DD  +LDT
Sbjct: 650  AYRTSPRLKDKKMD---AHPPRLFACSNKIGRFVIEEV--PGELMQEDLATDDVMLLDT 703


>ref|XP_853737.1| PREDICTED: similar to Gelsolin precursor (Actin-depolymerizing
           factor) (ADF) (Brevin) (AGEL) isoform 2 [Canis
           familiaris].
          Length = 781

 Score =  261 bits (668), Expect = 6e-70
 Identities = 136/278 (48%), Positives = 179/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL +WRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G + S+
Sbjct: 62  KEPGLQVWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGKECSQ 120

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 121 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 180

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SWDSFN GDCFILDLG NI+ WCG+ SN  E+ KA
Sbjct: 181 EV--VVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSNSNRYEKLKA 238

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+AQV +  +G EP  M+QVLGPKP L  G  E+    D  N + A 
Sbjct: 239 TQVSKGIRDNERSGRAQVHVSEEGAEPEAMLQVLGPKPALPAG-AEDTAKEDAANRKLAK 297

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 298 LYKVSNGAGTMSVSLVADENPFAQGALRSEDCFILDHG 335



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 78/273 (28%), Positives = 115/273 (42%), Gaps = 7/273 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARE--NQGIFFSGDSYLVLHNGPEELSHLHLWI--GHQSSRDEQGACA 359
            +WR      VP++      G FF    YL++H    E          G QS++DE  A A
Sbjct: 447  VWRPRTSNRVPMSPHLATSGFFFFLRFYLLIHERHRERQRPRQREKQGAQSTQDEVAASA 506

Query: 360  MLAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAI 536
            +L   L+  LG  PVQ R VQG E    MS F  + +   +GG          G T  A 
Sbjct: 507  ILTAQLDEELGGSPVQSRVVQGKEPAHLMSLFGGKPMIVYKGGT-----SRDGGQTAPAS 561

Query: 537  RKLYQVKGKKN--IRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLA 710
             +L+QV+   +   RA E      + N+ D F+L      + W GA ++  E++ A++L 
Sbjct: 562  TRLFQVRASSSGATRAVEIMPKAGALNSNDAFVLKTPSAAYLWVGAGASEAEKSGAQELL 621

Query: 711  LAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKV 890
              +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  
Sbjct: 622  RVLR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFAC 671

Query: 891  SDATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            S+  G+  + +V        E L  DD  +LDT
Sbjct: 672  SNKIGRFVIEEV--PGELMQEDLATDDVMLLDT 702


>ref|XP_532049.2| PREDICTED: similar to Gelsolin precursor (Actin-depolymerizing
           factor) (ADF) (Brevin) (AGEL) isoform 1 [Canis
           familiaris].
          Length = 736

 Score =  235 bits (600), Expect = 4e-62
 Identities = 123/251 (49%), Positives = 160/251 (63%), Gaps = 5/251 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL +WRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G + S+
Sbjct: 62  KEPGLQVWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGKECSQ 120

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 121 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 180

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SWDSFN GDCFILDLG NI+ WCG+ SN  E+ KA
Sbjct: 181 EV--VVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSNSNRYEKLKA 238

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+AQV +  +G EP  M+QVLGPKP L  G  E+    D  N + A 
Sbjct: 239 TQVSKGIRDNERSGRAQVHVSEEGAEPEAMLQVLGPKPALPAG-AEDTAKEDAANRKLAK 297

Query: 879 LYKVSDATGQM 911
           LYKVS+  G M
Sbjct: 298 LYKVSNGAGTM 308



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 70/239 (29%), Positives = 104/239 (43%), Gaps = 3/239 (1%)
 Frame = +3

Query: 282  NGPEELSHLHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYF-P 458
            +G  E     +W G QS++DE  A A+L   L+  LG  PVQ R VQG E    MS F  
Sbjct: 436  SGDREAFIFRVWQGAQSTQDEVAASAILTAQLDEELGGSPVQSRVVQGKEPAHLMSLFGG 495

Query: 459  RGLKYQEGGVESAFHKTSSGATPAAIRKLYQVKGKKN--IRATERALSWDSFNTGDCFIL 632
            + +   +GG          G T  A  +L+QV+   +   RA E      + N+ D F+L
Sbjct: 496  KPMIVYKGGT-----SRDGGQTAPASTRLFQVRASSSGATRAVEIMPKAGALNSNDAFVL 550

Query: 633  DLGQNIFAWCGAKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKP 812
                  + W GA ++  E++ A++L   +R       AQ   V +G EP    + LG K 
Sbjct: 551  KTPSAAYLWVGAGASEAEKSGAQELLRVLR-------AQPVQVAEGSEPDGFWEALGGKA 603

Query: 813  TLKEGNPEEDLTADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
              +     +D   D   A    L+  S+  G+  + +V        E L  DD  +LDT
Sbjct: 604  AYRTSPRLKDKKMD---AHPPRLFACSNKIGRFVIEEV--PGELMQEDLATDDVMLLDT 657


>ref|XP_532479.2| PREDICTED: similar to Adseverin (Scinderin) [Canis familiaris].
          Length = 731

 Score =  215 bits (548), Expect = 5e-56
 Identities = 103/225 (45%), Positives = 155/225 (68%)
 Frame = +3

Query: 321 GHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAF 500
           G + ++DE  A A+  V L+  LG +PVQ RE+QG ES  F+ YF  GLKY+ GGV S  
Sbjct: 83  GKECTQDESTAAAIFTVQLDDYLGGKPVQSRELQGYESTDFVGYFKGGLKYKAGGVASGL 142

Query: 501 HKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNI 680
           +   +    A  ++L  VKG++ +RATE  L+WDSFN GDCFI+DLG  I+ WCG+  N 
Sbjct: 143 NHVLTNDLTA--KRLLHVKGRRVVRATEVPLTWDSFNKGDCFIIDLGTEIYQWCGSSCNK 200

Query: 681 LERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQK 860
            ER KA  +A+ IRD+ER+G++Q+ +V +G EP+++ +VLG KP L++G+ ++D+ AD  
Sbjct: 201 YERLKASQVAIGIRDNERKGRSQLIVVEEGSEPSELRRVLGTKPELRDGDDDDDIVADIT 260

Query: 861 NAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTGS 995
           N + A LY VSDA+G M +  VA+ +PF++ +L+ ++CF+LD G+
Sbjct: 261 NRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGA 305



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 76/273 (27%), Positives = 119/273 (43%), Gaps = 6/273 (2%)
 Frame = +3

Query: 186  LHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSHLHLWIGHQSSRDEQGACAML 365
            + IWRVE    V + + + G F+ GD Y++L+  P     ++ W G  ++RDE    A L
Sbjct: 414  VEIWRVENNGRVEIDQNSYGEFYGGDCYIILYTYPGG-QIIYTWQGANATRDELTTSAFL 472

Query: 366  AVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIRK 542
             V L+  L  + VQ R  QG E    +S F  + L   + G          G  PA   +
Sbjct: 473  TVQLDRSLRGQAVQIRVSQGKEPAHLLSLFKDKPLIIYKNGTSK-----KGGQAPAPPTR 527

Query: 543  LYQVKGKKNIRATERALSWD----SFNTGDCFILDLGQNI-FAWCGAKSNILERNKARDL 707
            L+QV  ++N+ +  R +  D    S N+ D F+L L QN  + W G  ++  E   A  +
Sbjct: 528  LFQV--RRNLASITRIMEVDVDAQSLNSNDVFVLKLRQNNGYIWIGKGASQEEEKGAEYV 585

Query: 708  ALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYK 887
            A  +       K +   + +G+EP +    LG K   +       L   Q       LY 
Sbjct: 586  ASVL-------KCKTTRIQEGKEPEEFWNSLGGKKDYQ----TSPLLETQAEDHPPRLYG 634

Query: 888  VSDATGQMNLNKVADSSPFAVELLIPDDCFVLD 986
             S+ TG+  + +V     F  + L  DD  +LD
Sbjct: 635  CSNKTGRFVIEEV--PGEFTQDDLAEDDVMLLD 665


  Database: RefSeq49_CP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,874,504
  Number of sequences in database:  33,336
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33336
Number of Hits to DB: 44,621,918
Number of extensions: 1382622
Number of successful extensions: 6663
Number of sequences better than 1.0e-05: 18
Number of HSP's gapped: 6563
Number of HSP's successfully gapped: 30
Length of query: 333
Length of database: 18,874,504
Length adjustment: 103
Effective length of query: 230
Effective length of database: 15,440,896
Effective search space: 3551406080
Effective search space used: 3551406080
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 34 (17.7 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007642
         (999 letters)

Database: RefSeq49_MP.fasta 
           30,036 sequences; 15,617,559 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_031625.2| macrophage-capping protein isoform 1 [Mus muscu...   556   e-159
Alignment   gi|NP_001035999.1| macrophage-capping protein isoform 2 [Mus mu...   556   e-159
Alignment   gi|NP_001193298.1| gelsolin isoform 2 [Mus musculus].                266   2e-71
Alignment   gi|NP_001193297.1| gelsolin isoform 2 [Mus musculus].                266   2e-71
Alignment   gi|NP_001193296.1| gelsolin isoform 2 [Mus musculus].                266   2e-71
Alignment   gi|NP_666232.2| gelsolin isoform 1 precursor [Mus musculus].         266   2e-71
Alignment   gi|NP_033158.2| adseverin isoform 2 [Mus musculus].                  259   2e-69
Alignment   gi|NP_001139668.1| adseverin isoform 1 [Mus musculus].               259   2e-69
Alignment   gi|NP_033535.2| villin-1 [Mus musculus].                             207   1e-53
Alignment   gi|NP_033765.2| advillin [Mus musculus].                             201   6e-52

>ref|NP_031625.2| macrophage-capping protein isoform 1 [Mus musculus].
          Length = 349

 Score =  556 bits (1434), Expect = e-159
 Identities = 271/289 (93%), Positives = 279/289 (96%)
 Frame = +3

Query: 126 MYTSIPQSGSPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH 305
           MYT IPQSGSPFPASVQDPGLHIWRVEKLKPVP+ARE+ GIFFSGDSYLVLHNGPEE SH
Sbjct: 1   MYTPIPQSGSPFPASVQDPGLHIWRVEKLKPVPIARESHGIFFSGDSYLVLHNGPEEASH 60

Query: 306 LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 485
           LHLWIG QSSRDEQGACA+LAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKY+EGG
Sbjct: 61  LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYREGG 120

Query: 486 VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 665
           VESAFHKT+SGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG
Sbjct: 121 VESAFHKTTSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 180

Query: 666 AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL 845
            KSNILERNKARDLALAIRDSERQGKAQVEI+TDGEEPA+MIQVLGPKP LKEGNPEED+
Sbjct: 181 GKSNILERNKARDLALAIRDSERQGKAQVEIITDGEEPAEMIQVLGPKPALKEGNPEEDI 240

Query: 846 TADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           TADQ NAQAAALYKVSDATGQMNL KVADSSPFA ELLIPDDCFVLD G
Sbjct: 241 TADQTNAQAAALYKVSDATGQMNLTKVADSSPFASELLIPDDCFVLDNG 289


>ref|NP_001035999.1| macrophage-capping protein isoform 2 [Mus musculus].
          Length = 349

 Score =  556 bits (1434), Expect = e-159
 Identities = 271/289 (93%), Positives = 279/289 (96%)
 Frame = +3

Query: 126 MYTSIPQSGSPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH 305
           MYT IPQSGSPFPASVQDPGLHIWRVEKLKPVP+ARE+ GIFFSGDSYLVLHNGPEE SH
Sbjct: 1   MYTPIPQSGSPFPASVQDPGLHIWRVEKLKPVPIARESHGIFFSGDSYLVLHNGPEEASH 60

Query: 306 LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 485
           LHLWIG QSSRDEQGACA+LAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKY+EGG
Sbjct: 61  LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYREGG 120

Query: 486 VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 665
           VESAFHKT+SGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG
Sbjct: 121 VESAFHKTTSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 180

Query: 666 AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL 845
            KSNILERNKARDLALAIRDSERQGKAQVEI+TDGEEPA+MIQVLGPKP LKEGNPEED+
Sbjct: 181 GKSNILERNKARDLALAIRDSERQGKAQVEIITDGEEPAEMIQVLGPKPALKEGNPEEDI 240

Query: 846 TADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           TADQ NAQAAALYKVSDATGQMNL KVADSSPFA ELLIPDDCFVLD G
Sbjct: 241 TADQTNAQAAALYKVSDATGQMNLTKVADSSPFASELLIPDDCFVLDNG 289


>ref|NP_001193298.1| gelsolin isoform 2 [Mus musculus].
          Length = 731

 Score =  266 bits (679), Expect = 2e-71
 Identities = 139/278 (50%), Positives = 180/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL IWRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G++ S+
Sbjct: 13  KEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 71

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F  YF  GLKY++GGV S F      
Sbjct: 72  DESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFSGYFKSGLKYKKGGVASGFKHVVPN 131

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SWDSFN GDCFILDLG NI+ WCG+ SN  ER KA
Sbjct: 132 EV--VVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKA 189

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+AQV +  +G EP  M+QVLGPKP L EG  E+    D  N + A 
Sbjct: 190 TQVSKGIRDNERSGRAQVHVSEEGGEPEAMLQVLGPKPALPEGT-EDTAKEDAANRRLAK 248

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 249 LYKVSNGAGSMSVSLVADENPFAQGALRSEDCFILDHG 286



 Score =  103 bits (257), Expect = 2e-22
 Identities = 84/272 (30%), Positives = 124/272 (45%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
            IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 398  IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 457

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L   L+  LG  PVQ R VQG E    MS F  + +   +GG      +      PA+IR
Sbjct: 458  LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTS----RDGGQTAPASIR 513

Query: 540  KLYQVKGKKN--IRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
             L+QV+   +   RA E      + N+ D F+L      + W GA ++  E+  A++L  
Sbjct: 514  -LFQVRASSSGATRAVEVMPKSGALNSNDAFVLKTPSAAYLWVGAGASEAEKTGAQELLK 572

Query: 714  AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
             +R    Q       V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 573  VLRSQHVQ-------VEEGSEPDAFWEALGGKTAYRTSPRLKDKKMD---AHPPRLFACS 622

Query: 894  DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            +  G+  + +V        E L  DD  +LDT
Sbjct: 623  NRIGRFVIEEV--PGELMQEDLATDDVMLLDT 652


>ref|NP_001193297.1| gelsolin isoform 2 [Mus musculus].
          Length = 731

 Score =  266 bits (679), Expect = 2e-71
 Identities = 139/278 (50%), Positives = 180/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL IWRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G++ S+
Sbjct: 13  KEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 71

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F  YF  GLKY++GGV S F      
Sbjct: 72  DESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFSGYFKSGLKYKKGGVASGFKHVVPN 131

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SWDSFN GDCFILDLG NI+ WCG+ SN  ER KA
Sbjct: 132 EV--VVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKA 189

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+AQV +  +G EP  M+QVLGPKP L EG  E+    D  N + A 
Sbjct: 190 TQVSKGIRDNERSGRAQVHVSEEGGEPEAMLQVLGPKPALPEGT-EDTAKEDAANRRLAK 248

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 249 LYKVSNGAGSMSVSLVADENPFAQGALRSEDCFILDHG 286



 Score =  103 bits (257), Expect = 2e-22
 Identities = 84/272 (30%), Positives = 124/272 (45%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
            IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 398  IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 457

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L   L+  LG  PVQ R VQG E    MS F  + +   +GG      +      PA+IR
Sbjct: 458  LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTS----RDGGQTAPASIR 513

Query: 540  KLYQVKGKKN--IRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
             L+QV+   +   RA E      + N+ D F+L      + W GA ++  E+  A++L  
Sbjct: 514  -LFQVRASSSGATRAVEVMPKSGALNSNDAFVLKTPSAAYLWVGAGASEAEKTGAQELLK 572

Query: 714  AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
             +R    Q       V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 573  VLRSQHVQ-------VEEGSEPDAFWEALGGKTAYRTSPRLKDKKMD---AHPPRLFACS 622

Query: 894  DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            +  G+  + +V        E L  DD  +LDT
Sbjct: 623  NRIGRFVIEEV--PGELMQEDLATDDVMLLDT 652


>ref|NP_001193296.1| gelsolin isoform 2 [Mus musculus].
          Length = 731

 Score =  266 bits (679), Expect = 2e-71
 Identities = 139/278 (50%), Positives = 180/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL IWRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G++ S+
Sbjct: 13  KEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 71

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F  YF  GLKY++GGV S F      
Sbjct: 72  DESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFSGYFKSGLKYKKGGVASGFKHVVPN 131

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SWDSFN GDCFILDLG NI+ WCG+ SN  ER KA
Sbjct: 132 EV--VVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKA 189

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+AQV +  +G EP  M+QVLGPKP L EG  E+    D  N + A 
Sbjct: 190 TQVSKGIRDNERSGRAQVHVSEEGGEPEAMLQVLGPKPALPEGT-EDTAKEDAANRRLAK 248

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 249 LYKVSNGAGSMSVSLVADENPFAQGALRSEDCFILDHG 286



 Score =  103 bits (257), Expect = 2e-22
 Identities = 84/272 (30%), Positives = 124/272 (45%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
            IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 398  IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 457

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L   L+  LG  PVQ R VQG E    MS F  + +   +GG      +      PA+IR
Sbjct: 458  LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTS----RDGGQTAPASIR 513

Query: 540  KLYQVKGKKN--IRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
             L+QV+   +   RA E      + N+ D F+L      + W GA ++  E+  A++L  
Sbjct: 514  -LFQVRASSSGATRAVEVMPKSGALNSNDAFVLKTPSAAYLWVGAGASEAEKTGAQELLK 572

Query: 714  AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
             +R    Q       V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 573  VLRSQHVQ-------VEEGSEPDAFWEALGGKTAYRTSPRLKDKKMD---AHPPRLFACS 622

Query: 894  DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            +  G+  + +V        E L  DD  +LDT
Sbjct: 623  NRIGRFVIEEV--PGELMQEDLATDDVMLLDT 652


>ref|NP_666232.2| gelsolin isoform 1 precursor [Mus musculus].
          Length = 780

 Score =  266 bits (679), Expect = 2e-71
 Identities = 139/278 (50%), Positives = 180/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL IWRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G++ S+
Sbjct: 62  KEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 120

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F  YF  GLKY++GGV S F      
Sbjct: 121 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFSGYFKSGLKYKKGGVASGFKHVVPN 180

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SWDSFN GDCFILDLG NI+ WCG+ SN  ER KA
Sbjct: 181 EV--VVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKA 238

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+AQV +  +G EP  M+QVLGPKP L EG  E+    D  N + A 
Sbjct: 239 TQVSKGIRDNERSGRAQVHVSEEGGEPEAMLQVLGPKPALPEGT-EDTAKEDAANRRLAK 297

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 298 LYKVSNGAGSMSVSLVADENPFAQGALRSEDCFILDHG 335



 Score =  103 bits (257), Expect = 2e-22
 Identities = 84/272 (30%), Positives = 124/272 (45%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
            IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 447  IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 506

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L   L+  LG  PVQ R VQG E    MS F  + +   +GG      +      PA+IR
Sbjct: 507  LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTS----RDGGQTAPASIR 562

Query: 540  KLYQVKGKKN--IRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
             L+QV+   +   RA E      + N+ D F+L      + W GA ++  E+  A++L  
Sbjct: 563  -LFQVRASSSGATRAVEVMPKSGALNSNDAFVLKTPSAAYLWVGAGASEAEKTGAQELLK 621

Query: 714  AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
             +R    Q       V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 622  VLRSQHVQ-------VEEGSEPDAFWEALGGKTAYRTSPRLKDKKMD---AHPPRLFACS 671

Query: 894  DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            +  G+  + +V        E L  DD  +LDT
Sbjct: 672  NRIGRFVIEEV--PGELMQEDLATDDVMLLDT 701


>ref|NP_033158.2| adseverin isoform 2 [Mus musculus].
          Length = 615

 Score =  259 bits (663), Expect = 2e-69
 Identities = 128/282 (45%), Positives = 187/282 (66%), Gaps = 3/282 (1%)
 Frame = +3

Query: 159 FPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELS---HLHLWIGHQ 329
           F  + Q  GL +WRVEKL+ VPV +   G F+ GD+YLVLH           LH W+G +
Sbjct: 10  FARAGQQAGLQVWRVEKLELVPVPQGAYGDFYVGDAYLVLHTTKSSRGFSYRLHFWLGKE 69

Query: 330 SSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKT 509
            S+DE  A A+  V ++  LG +PVQ RE+QG ES  F+ YF  GLKY+ GGV S  +  
Sbjct: 70  CSQDESTAAAIFTVQMDDYLGGKPVQSRELQGYESTDFVGYFKGGLKYKAGGVASGLNHV 129

Query: 510 SSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILER 689
            +    A  ++L  VKG++ +RATE  LSW+SFN GDCFI+DLG  I+ WCG+  N  ER
Sbjct: 130 LTNDLTA--KRLLHVKGRRVVRATEVPLSWESFNKGDCFIIDLGTEIYQWCGSSCNKYER 187

Query: 690 NKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQ 869
            KA  +A+ IRD+ER+G++Q+ +V +G EP+++++VLG KP L +G+ ++D+ AD  N +
Sbjct: 188 LKASQVAIGIRDNERKGRSQLIVVEEGSEPSELMKVLGRKPELPDGDNDDDVVADISNRK 247

Query: 870 AAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTGS 995
            A LY VSDA+G M +  VA+ +PF++ +L+ ++CF+LD G+
Sbjct: 248 MAKLYMVSDASGSMKVTLVAEENPFSMGMLLSEECFILDHGA 289



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 61/212 (28%), Positives = 95/212 (44%), Gaps = 13/212 (6%)
 Frame = +3

Query: 183  GLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSHLHLWIGHQSSRDEQGACAM 362
            G+ IWRVE    V +   + G F+ GD Y++L+  P     ++ W G  ++RDE    A 
Sbjct: 397  GVEIWRVENSGRVQIDPSSYGEFYGGDCYIILYTYPRG-QIIYTWQGANATRDELTMSAF 455

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L V L+  LG + VQ R  QG E    +S F  + L   + G          G  PA   
Sbjct: 456  LTVQLDRSLGGQAVQVRVSQGKEPAHLLSLFKDKPLIIYKNGTSK-----KEGQAPAPPT 510

Query: 540  KLYQVKGKKNIRATERAL---------SWDSFNTGDCFILDLGQNIFAWCGAKSNILERN 692
            +L+QV  ++N+ +  R +         + D     D  +LD  + IF W G  +N +E+ 
Sbjct: 511  RLFQV--RRNLASITRIVEIEEVPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKK 568

Query: 693  ---KARDLALAIRDSERQGKAQVEIVTDGEEP 779
               K+  + L    S R  +  + I+  G EP
Sbjct: 569  ESVKSAKMYLETDPSGRDKRTPIVIIKQGHEP 600


>ref|NP_001139668.1| adseverin isoform 1 [Mus musculus].
          Length = 715

 Score =  259 bits (663), Expect = 2e-69
 Identities = 128/282 (45%), Positives = 187/282 (66%), Gaps = 3/282 (1%)
 Frame = +3

Query: 159 FPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELS---HLHLWIGHQ 329
           F  + Q  GL +WRVEKL+ VPV +   G F+ GD+YLVLH           LH W+G +
Sbjct: 10  FARAGQQAGLQVWRVEKLELVPVPQGAYGDFYVGDAYLVLHTTKSSRGFSYRLHFWLGKE 69

Query: 330 SSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKT 509
            S+DE  A A+  V ++  LG +PVQ RE+QG ES  F+ YF  GLKY+ GGV S  +  
Sbjct: 70  CSQDESTAAAIFTVQMDDYLGGKPVQSRELQGYESTDFVGYFKGGLKYKAGGVASGLNHV 129

Query: 510 SSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILER 689
            +    A  ++L  VKG++ +RATE  LSW+SFN GDCFI+DLG  I+ WCG+  N  ER
Sbjct: 130 LTNDLTA--KRLLHVKGRRVVRATEVPLSWESFNKGDCFIIDLGTEIYQWCGSSCNKYER 187

Query: 690 NKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQ 869
            KA  +A+ IRD+ER+G++Q+ +V +G EP+++++VLG KP L +G+ ++D+ AD  N +
Sbjct: 188 LKASQVAIGIRDNERKGRSQLIVVEEGSEPSELMKVLGRKPELPDGDNDDDVVADISNRK 247

Query: 870 AAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTGS 995
            A LY VSDA+G M +  VA+ +PF++ +L+ ++CF+LD G+
Sbjct: 248 MAKLYMVSDASGSMKVTLVAEENPFSMGMLLSEECFILDHGA 289



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 77/274 (28%), Positives = 120/274 (43%), Gaps = 6/274 (2%)
 Frame = +3

Query: 183  GLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSHLHLWIGHQSSRDEQGACAM 362
            G+ IWRVE    V +   + G F+ GD Y++L+  P     ++ W G  ++RDE    A 
Sbjct: 397  GVEIWRVENSGRVQIDPSSYGEFYGGDCYIILYTYPRG-QIIYTWQGANATRDELTMSAF 455

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L V L+  LG + VQ R  QG E    +S F  + L   + G          G  PA   
Sbjct: 456  LTVQLDRSLGGQAVQVRVSQGKEPAHLLSLFKDKPLIIYKNGTSK-----KEGQAPAPPT 510

Query: 540  KLYQVKGKKNIRATERALSWD----SFNTGDCFILDLGQNI-FAWCGAKSNILERNKARD 704
            +L+QV  ++N+ +  R +  D    S N+ D F+L L +N  F W G  ++  E   A  
Sbjct: 511  RLFQV--RRNLASITRIVEVDVDANSLNSNDTFVLKLPRNNGFIWIGKGASQEEEKGAEY 568

Query: 705  LALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALY 884
            +A  +       K +   + +G+EP +    LG +   +     E    D        LY
Sbjct: 569  VADVL-------KCKASRIQEGKEPEEFWNSLGGRGDYQTSPLLETRAED----HPPRLY 617

Query: 885  KVSDATGQMNLNKVADSSPFAVELLIPDDCFVLD 986
              S+ TG+  + +V     F  + L  DD  +LD
Sbjct: 618  GCSNKTGRFIIEEV--PGEFTQDDLAEDDVMLLD 649


>ref|NP_033535.2| villin-1 [Mus musculus].
          Length = 827

 Score =  207 bits (526), Expect = 1e-53
 Identities = 121/287 (42%), Positives = 167/287 (58%), Gaps = 10/287 (3%)
 Frame = +3

Query: 168 SVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL--HNGPEELSH-LHLWIGHQSSR 338
           ++  PG+ IWR+E ++ VPV     G FF GD Y+VL  H     LS+ +H WIG  SS+
Sbjct: 13  NITTPGIQIWRIEAMQMVPVPSSTFGSFFDGDCYVVLAIHKTSSTLSYDIHYWIGQDSSQ 72

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DEQGA A+    ++  L  R VQHREVQGNES+ F SYF +GL  ++GGV S      + 
Sbjct: 73  DEQGAAAIYTTQMDDYLKGRAVQHREVQGNESETFRSYFKQGLVIRKGGVASGMKHVETN 132

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
           +    +++L  VKGK+N+ A E  +SW SFN GD F+LDLG+ I  W G +SN +ER + 
Sbjct: 133 SCD--VQRLLHVKGKRNVLAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESNRMERLRG 190

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPAD-------MIQVLGPKPTLKEGNPEEDLTADQ 857
             LA  IRD ER G+  V +V DGE+  D       M  VLGP+  LK      D   + 
Sbjct: 191 MALAKEIRDQERGGRTYVGVV-DGEKEGDSPQLMAIMNHVLGPRKELKAA--ISDSVVEP 247

Query: 858 KNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTGSV 998
               A  LY VSD+ G++ + +VA + P   +LL  +DC++LD G +
Sbjct: 248 AAKAALKLYHVSDSEGKLVVREVA-TRPLTQDLLKHEDCYILDQGGL 293



 Score =  107 bits (266), Expect = 2e-23
 Identities = 81/272 (29%), Positives = 127/272 (46%), Gaps = 5/272 (1%)
 Frame = +3

Query: 186  LHIWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGAC 356
            + +WR+E L+ VPV  +  G F+ GD YL+L+    G ++   L++W G Q+S+DE  A 
Sbjct: 400  VQVWRIEDLELVPVESKWLGHFYGGDCYLLLYTYLIGEKQHYLLYIWQGSQASQDEIAAS 459

Query: 357  AMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSGATPAAI 536
            A  AV L+    + PVQ R   G E    MS F   +   +GG         +   P   
Sbjct: 460  AYQAVLLDQKYNDEPVQIRVTMGKEPPHLMSIFKGRMVVYQGGT-----SRKNNLEPVPS 514

Query: 537  RKLYQVKGKK--NIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLA 710
             +L+QV+G    N +A E      S N+ D FIL      + WCG   +  ER  A+ +A
Sbjct: 515  TRLFQVRGTNADNTKAFEVTARATSLNSNDVFILKTPSCCYLWCGKGCSGDEREMAKMVA 574

Query: 711  LAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKV 890
              I  +E+Q      +V +G+EPA+    LG K         +    ++       L++ 
Sbjct: 575  DTISRTEKQ------VVVEGQEPANFWMALGGKAPYANTKRLQ----EENQVITPRLFEC 624

Query: 891  SDATGQMNLNKVADSSPFAVELLIPDDCFVLD 986
            S+ TG+    ++ D   F  + L  +D F+LD
Sbjct: 625  SNQTGRFLATEIFD---FNQDDLEEEDVFLLD 653


>ref|NP_033765.2| advillin [Mus musculus].
          Length = 819

 Score =  201 bits (512), Expect = 6e-52
 Identities = 117/287 (40%), Positives = 163/287 (56%), Gaps = 9/287 (3%)
 Frame = +3

Query: 153 SPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIG 323
           S F A   DP +  WR+EK++   V     G F+ GD Y+VL     G     ++H WIG
Sbjct: 5   SAFRAVSNDPRIITWRIEKMELALVPLSAHGNFYEGDCYIVLSTRRVGSLLSQNIHFWIG 64

Query: 324 HQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFH 503
             SS+DEQ   A+    L+  LG  PVQHREVQ +ESD F  YF +G+ Y++GGV S   
Sbjct: 65  KDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMK 124

Query: 504 KTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNIL 683
              +      +++L  VKGK+NI+ATE  +SWDSFN GD F+LDLG  I  W G +SN  
Sbjct: 125 HVETNTYD--VKRLLHVKGKRNIQATEVEMSWDSFNRGDVFLLDLGMVIIQWNGPESNSG 182

Query: 684 ERNKARDLALAIRDSERQGKAQVEIVTDGEEPAD------MIQVLGPKPTLKEGNPEEDL 845
           ER KA  LA  IRD ER G+A++ ++   +E A       +   LG +  +K    +E +
Sbjct: 183 ERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPGLMTVLQDTLGRRSMIKPAVSDEIM 242

Query: 846 TADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLD 986
             DQ+   +  LY VSD  GQ+++ +VA + P   +LL  DDC++LD
Sbjct: 243 --DQQQKSSIMLYHVSDTAGQLSVTEVA-TRPLVQDLLNHDDCYILD 286



 Score =  110 bits (276), Expect = 1e-24
 Identities = 86/274 (31%), Positives = 125/274 (45%), Gaps = 6/274 (2%)
 Frame = +3

Query: 186  LHIWRVEKLKPVPVARENQGIFFSGDSYLVLH----NGPEELSHLHLWIGHQSSRDEQGA 353
            + +WR+E L+ VPV  +  G F+ GD YLVL+    NG      L++W G  +SRDE  A
Sbjct: 397  VEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVNGKPHYI-LYIWQGRHASRDELAA 455

Query: 354  CAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSGATPAA 533
             A  AV ++      PVQ R   G E   FM+ F   L   EGG             P  
Sbjct: 456  SAYRAVEVDQQFDGAPVQVRVSMGKEPRHFMAIFKGKLVIYEGGT-----SRKGNEEPDP 510

Query: 534  IRKLYQVKG--KKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDL 707
              +L+Q+ G  K N +A E + S  S N+ D F+L      + W G  S+  ER  A++L
Sbjct: 511  PVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKEL 570

Query: 708  ALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYK 887
               + D         + V +G+EP +   +LG K         +  T D +      L++
Sbjct: 571  VDLLCD------GNADTVAEGQEPPEFWDLLGGKTAYANDKRLQQETLDVQ----VRLFE 620

Query: 888  VSDATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
             S+ TG+  + +V D   F  E L P D  +LDT
Sbjct: 621  CSNKTGRFLVTEVTD---FTQEDLSPGDVMLLDT 651


  Database: RefSeq49_MP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 15,617,559
  Number of sequences in database:  30,036
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 30036
Number of Hits to DB: 36,873,259
Number of extensions: 1115812
Number of successful extensions: 4776
Number of sequences better than 1.0e-05: 14
Number of HSP's gapped: 4685
Number of HSP's successfully gapped: 24
Length of query: 333
Length of database: 15,617,559
Length adjustment: 102
Effective length of query: 231
Effective length of database: 12,553,887
Effective search space: 2899947897
Effective search space used: 2899947897
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 34 (17.7 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007642
         (999 letters)

Database: RefSeq49_SP.fasta 
           24,897 sequences; 11,343,932 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|XP_003124998.1| PREDICTED: macrophage-capping protein-like i...   580   e-166
Alignment   gi|XP_003124997.1| PREDICTED: macrophage-capping protein-like i...   580   e-166
Alignment   gi|XP_003124996.1| PREDICTED: macrophage-capping protein-like i...   580   e-166
Alignment   gi|XP_003124995.1| PREDICTED: macrophage-capping protein-like i...   580   e-166
Alignment   gi|XP_003130226.2| PREDICTED: adseverin-like [Sus scrofa].           257   8e-69
Alignment   gi|XP_001925202.2| PREDICTED: villin-1 [Sus scrofa].                 206   2e-53
Alignment   gi|XP_003361934.1| PREDICTED: advillin [Sus scrofa].                 205   4e-53
Alignment   gi|XP_003122157.2| PREDICTED: gelsolin-like [Sus scrofa].            119   3e-27
Alignment   gi|XP_003122158.2| PREDICTED: gelsolin [Sus scrofa].                 102   3e-22
Alignment   gi|XP_003358416.1| PREDICTED: villin-like protein, partial [Sus...    76   3e-14

>ref|XP_003124998.1| PREDICTED: macrophage-capping protein-like isoform 4 [Sus scrofa].
          Length = 349

 Score =  580 bits (1496), Expect = e-166
 Identities = 286/289 (98%), Positives = 287/289 (99%)
 Frame = +3

Query: 126 MYTSIPQSGSPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH 305
           MYTSIPQSGSPFPASVQDPGL+IWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH
Sbjct: 1   MYTSIPQSGSPFPASVQDPGLYIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH 60

Query: 306 LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 485
           LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG
Sbjct: 61  LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120

Query: 486 VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 665
           VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG
Sbjct: 121 VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 180

Query: 666 AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL 845
           AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL
Sbjct: 181 AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL 240

Query: 846 TADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           TADQKNAQAAALYKVSDATGQMNL KVADSSPFAVELLIPDDCFVLD G
Sbjct: 241 TADQKNAQAAALYKVSDATGQMNLTKVADSSPFAVELLIPDDCFVLDNG 289


>ref|XP_003124997.1| PREDICTED: macrophage-capping protein-like isoform 3 [Sus scrofa].
          Length = 349

 Score =  580 bits (1496), Expect = e-166
 Identities = 286/289 (98%), Positives = 287/289 (99%)
 Frame = +3

Query: 126 MYTSIPQSGSPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH 305
           MYTSIPQSGSPFPASVQDPGL+IWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH
Sbjct: 1   MYTSIPQSGSPFPASVQDPGLYIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH 60

Query: 306 LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 485
           LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG
Sbjct: 61  LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120

Query: 486 VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 665
           VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG
Sbjct: 121 VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 180

Query: 666 AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL 845
           AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL
Sbjct: 181 AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL 240

Query: 846 TADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           TADQKNAQAAALYKVSDATGQMNL KVADSSPFAVELLIPDDCFVLD G
Sbjct: 241 TADQKNAQAAALYKVSDATGQMNLTKVADSSPFAVELLIPDDCFVLDNG 289


>ref|XP_003124996.1| PREDICTED: macrophage-capping protein-like isoform 2 [Sus scrofa].
          Length = 349

 Score =  580 bits (1496), Expect = e-166
 Identities = 286/289 (98%), Positives = 287/289 (99%)
 Frame = +3

Query: 126 MYTSIPQSGSPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH 305
           MYTSIPQSGSPFPASVQDPGL+IWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH
Sbjct: 1   MYTSIPQSGSPFPASVQDPGLYIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH 60

Query: 306 LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 485
           LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG
Sbjct: 61  LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120

Query: 486 VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 665
           VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG
Sbjct: 121 VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 180

Query: 666 AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL 845
           AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL
Sbjct: 181 AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL 240

Query: 846 TADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           TADQKNAQAAALYKVSDATGQMNL KVADSSPFAVELLIPDDCFVLD G
Sbjct: 241 TADQKNAQAAALYKVSDATGQMNLTKVADSSPFAVELLIPDDCFVLDNG 289


>ref|XP_003124995.1| PREDICTED: macrophage-capping protein-like isoform 1 [Sus scrofa].
          Length = 349

 Score =  580 bits (1496), Expect = e-166
 Identities = 286/289 (98%), Positives = 287/289 (99%)
 Frame = +3

Query: 126 MYTSIPQSGSPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH 305
           MYTSIPQSGSPFPASVQDPGL+IWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH
Sbjct: 1   MYTSIPQSGSPFPASVQDPGLYIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH 60

Query: 306 LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 485
           LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG
Sbjct: 61  LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120

Query: 486 VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 665
           VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG
Sbjct: 121 VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 180

Query: 666 AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL 845
           AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL
Sbjct: 181 AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL 240

Query: 846 TADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           TADQKNAQAAALYKVSDATGQMNL KVADSSPFAVELLIPDDCFVLD G
Sbjct: 241 TADQKNAQAAALYKVSDATGQMNLTKVADSSPFAVELLIPDDCFVLDNG 289


>ref|XP_003130226.2| PREDICTED: adseverin-like [Sus scrofa].
          Length = 715

 Score =  257 bits (656), Expect = 8e-69
 Identities = 126/282 (44%), Positives = 184/282 (65%), Gaps = 3/282 (1%)
 Frame = +3

Query: 159 FPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEE---LSHLHLWIGHQ 329
           F  + +  GL +WR+EKL+ VPV     G F+ GD+YLVLH        +  LH W+G +
Sbjct: 10  FARAGKQAGLQVWRIEKLELVPVPESAYGDFYVGDAYLVLHTTQASRGFVYRLHFWLGKE 69

Query: 330 SSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKT 509
            ++DE  A A+  + ++  LG +PVQ+RE+QG ES  F+ YF  GLKY+ GGV S F+  
Sbjct: 70  CTQDESTAAAIFTIQMDDYLGGKPVQNRELQGYESTDFVGYFKGGLKYKAGGVASGFNHV 129

Query: 510 SSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILER 689
            +    A  ++L  VKG++ +RATE  LSWDSFN GDCFI+DLG  I+ W G+  N  ER
Sbjct: 130 LTNDLSA--QRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGSEIYQWFGSSCNKYER 187

Query: 690 NKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQ 869
            KA  +A  IRD+ER G++Q+ +V +G EP ++I+VLG KP L++G  ++D  AD  N +
Sbjct: 188 LKASQVATGIRDNERNGRSQLIVVEEGSEPPELIEVLGKKPELRDGEDDDDTIADITNRK 247

Query: 870 AAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTGS 995
            A LY VSDA+G M +  VA+ +PF++ +L+ ++CF+LD G+
Sbjct: 248 MAKLYMVSDASGSMRVTMVAEENPFSMAMLLSEECFILDHGA 289



 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 77/273 (28%), Positives = 120/273 (43%), Gaps = 6/273 (2%)
 Frame = +3

Query: 186  LHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSHLHLWIGHQSSRDEQGACAML 365
            + IWRVE    V + + + G F+ GD Y++L+  P     ++ W G  ++RDE    A L
Sbjct: 398  VEIWRVENNGRVEIDQNSYGEFYGGDCYIILYTYPRG-QIIYTWQGANATRDELTTSAFL 456

Query: 366  AVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIRK 542
             V L+  LG + VQ R  QG E    +S F  + L   + G        + G  PA   +
Sbjct: 457  TVQLDRSLGGQAVQIRVSQGKEPAHLLSLFKDKPLIIYKNGTSK-----NGGQAPAPPTR 511

Query: 543  LYQVKGKKNIRATERALSWD----SFNTGDCFILDLGQNI-FAWCGAKSNILERNKARDL 707
             +QV  ++N+ +  R +  D    S N+ D F+L L QN  + W G  ++  E   A  +
Sbjct: 512  FFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLQQNNGYIWIGKGASQEEEKGAEYV 569

Query: 708  ALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYK 887
            A  +       K +   + +GEEP +    LG K   +       L   Q       LY 
Sbjct: 570  ASVL-------KCKTTRIQEGEEPEEFWNSLGGKKDYQ----TSPLLETQAEEHLPRLYG 618

Query: 888  VSDATGQMNLNKVADSSPFAVELLIPDDCFVLD 986
             S+ TG+  + +V     F  + L  DD  +LD
Sbjct: 619  CSNKTGRFTIEEV--PGEFTQDDLAEDDVMLLD 649


>ref|XP_001925202.2| PREDICTED: villin-1 [Sus scrofa].
          Length = 827

 Score =  206 bits (523), Expect = 2e-53
 Identities = 120/286 (41%), Positives = 166/286 (58%), Gaps = 9/286 (3%)
 Frame = +3

Query: 168 SVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL--HNGPEELSH-LHLWIGHQSSR 338
           +V  PG+ IWR+E ++ VPV+    G FF GD Y+VL  H     LS+ +H WIG  SS+
Sbjct: 13  NVTTPGVQIWRIEAMQMVPVSSSTYGSFFDGDCYIVLAIHKTGSNLSYDIHYWIGQDSSQ 72

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DEQGA A+    ++  L  R VQHREVQGNES+ F  YF +G+  ++GGV S   K  + 
Sbjct: 73  DEQGAAAIYTTLMDDFLKGRAVQHREVQGNESEAFRGYFKQGIVIRKGGVASGMKKVETN 132

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
           +    I++L  VKGK+N+ A E  +SW SFN GD F+LDLG+ I  W G +SN +ER + 
Sbjct: 133 SYD--IQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESNRMERLRG 190

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPAD------MIQVLGPKPTLKEGNPEEDLTADQK 860
             LA  IRD ER G+  V +V   +E A       M  VLG +  LK   P  D   +  
Sbjct: 191 MTLAKEIRDQERGGRTYVGVVDGEDEKASPQLMEIMNYVLGQRKELKAAVP--DTVVEPA 248

Query: 861 NAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTGSV 998
              A  LY VSD+ G++ + +VA + P   +LL  +DC++LD G +
Sbjct: 249 LKAALKLYHVSDSEGKVVVREVA-TRPLTQDLLSHEDCYILDQGGL 293



 Score =  108 bits (270), Expect = 5e-24
 Identities = 86/274 (31%), Positives = 127/274 (46%), Gaps = 7/274 (2%)
 Frame = +3

Query: 186  LHIWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGAC 356
            + IWR+E L  VPV  +  G F+ GD YL+L+    G ++   L++W G Q+S+DE  A 
Sbjct: 400  VEIWRIENLDLVPVESKWVGHFYGGDCYLLLYTYLIGEKQHYLLYIWQGSQASQDEITAS 459

Query: 357  AMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSGATPAAI 536
            A  AV L+      PVQ R   G E    MS F   +   +GG   A     +   P   
Sbjct: 460  AYQAVILDQKYNNEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGTSRA-----NSTEPVPS 514

Query: 537  RKLYQVKGK--KNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLA 710
             +L+QV+G    N +A E      S N+ D F+L      + WCG   +  ER  A+ +A
Sbjct: 515  TRLFQVRGTSVNNTKAFEVPARATSLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVA 574

Query: 711  LAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGN--PEEDLTADQKNAQAAALY 884
              I  +E+Q      +V +G+EPA+    LG K          EE L    +      L+
Sbjct: 575  DTISRTEKQ------VVVEGQEPANFWMALGGKAPYASSKRLQEETLVITPR------LF 622

Query: 885  KVSDATGQMNLNKVADSSPFAVELLIPDDCFVLD 986
            + S+ TG+    ++ D   F  + L  DD F+LD
Sbjct: 623  ECSNQTGRFLATEIPD---FNQDDLEEDDVFLLD 653


>ref|XP_003361934.1| PREDICTED: advillin [Sus scrofa].
          Length = 816

 Score =  205 bits (521), Expect = 4e-53
 Identities = 119/287 (41%), Positives = 163/287 (56%), Gaps = 9/287 (3%)
 Frame = +3

Query: 153 SPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIG 323
           S F A   DPG+  WR+EK++   V     G F+ GD Y++L     G      +H WIG
Sbjct: 5   SAFRAVGNDPGIITWRIEKMELALVPLSAHGNFYEGDCYVILSTRRAGSLLSQDIHFWIG 64

Query: 324 HQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFH 503
             SS+DEQ   A+    L+  LG  PVQHREVQ +ESD F  YF +G+ Y++GGV S   
Sbjct: 65  KDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMK 124

Query: 504 KTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNIL 683
              +      +++L  VKGK+NIRATE  +SWDSFN GD F+LDLG+ I  W G +S+  
Sbjct: 125 HVETNTYD--VKRLLHVKGKRNIRATEVEVSWDSFNQGDVFLLDLGKVIIQWNGPESSSG 182

Query: 684 ERNKARDLALAIRDSERQGKAQVEIVTDGEEPAD------MIQVLGPKPTLKEGNPEEDL 845
           ER KA  LA  IRD ER G+A++ ++   +E A       +   LG +  +K   P+E  
Sbjct: 183 ERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPAIPDE-- 240

Query: 846 TADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLD 986
             DQ+      LY VSD+ GQ+ + +VA + P   ELL  DDC++LD
Sbjct: 241 ITDQQQKSNITLYHVSDSAGQLAVTEVA-TRPLVQELLNHDDCYILD 286



 Score =  109 bits (272), Expect = 3e-24
 Identities = 85/275 (30%), Positives = 129/275 (46%), Gaps = 7/275 (2%)
 Frame = +3

Query: 186  LHIWRVEKLKPVPVARENQGIFFSGDSYLVLH----NGPEELSHLHLWIGHQSSRDEQGA 353
            + +WR+E L+ VPV  +  G F+ GD YLVL+    NG      L++W G  +S+DE  A
Sbjct: 397  VEVWRIENLELVPVEHQWYGFFYGGDCYLVLYTYEMNGKPHYI-LYIWQGRHASQDELAA 455

Query: 354  CAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSGATPAA 533
             A  AV ++      PVQ R   G E   FM+ F   L   EGG           A P  
Sbjct: 456  SAYQAVEVDRQFDGAPVQVRVTMGKEPHHFMAIFKGKLVIFEGGT-----SRKGNAEPDP 510

Query: 534  IRKLYQVKG--KKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDL 707
              +L+Q++G  K N +A E      S N+ D F+L      + W G  S+  ER  A++L
Sbjct: 511  PVRLFQIQGNDKSNTKAVEVPAFTSSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKEL 570

Query: 708  ALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPK-PTLKEGNPEEDLTADQKNAQAAALY 884
            A  + D           V +G+EPA+   +LG K P   +   ++++   Q       L+
Sbjct: 571  ARFLCDGTE------NTVAEGQEPAEFWDLLGGKTPYANDKRLQQEILDVQPR-----LF 619

Query: 885  KVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            + S+ TG+  + ++ D   F  + L P D  +LDT
Sbjct: 620  ECSNKTGRFIVTEITD---FTQDDLNPGDVMLLDT 651


>ref|XP_003122157.2| PREDICTED: gelsolin-like [Sus scrofa].
          Length = 135

 Score =  119 bits (297), Expect = 3e-27
 Identities = 58/113 (51%), Positives = 77/113 (68%)
 Frame = +3

Query: 321 GHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAF 500
           G++ S+DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F
Sbjct: 8   GNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF 67

Query: 501 HKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAW 659
                     A+++L+QVKG++ +RATE  +SW+SFN GDCFILDLG  ++ W
Sbjct: 68  KHVV--PNEVAVQRLFQVKGRRVVRATEVPVSWESFNRGDCFILDLGNVMYQW 118


>ref|XP_003122158.2| PREDICTED: gelsolin [Sus scrofa].
          Length = 398

 Score =  102 bits (254), Expect = 3e-22
 Identities = 83/272 (30%), Positives = 119/272 (43%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192 IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
           IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 67  IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 126

Query: 363 LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
           L   L+  LG  PVQ R VQG E    MS F  + +    GG          G T  A  
Sbjct: 127 LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYRGGT-----SREGGQTAPAST 181

Query: 540 KLYQVKGKKN--IRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
           +L+QV+   +   RA E      + N+ D F+L      + W G  ++  E+  A++L  
Sbjct: 182 RLFQVRASSSGATRAVEVIPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLR 241

Query: 714 AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
            +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 242 VLR-------AQPVQVAEGSEPDSFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFACS 291

Query: 894 DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
           +  G+     V        E L  DD  +LDT
Sbjct: 292 NKIGRF----VVSPGELMQEDLATDDVMLLDT 319


>ref|XP_003358416.1| PREDICTED: villin-like protein, partial [Sus scrofa].
          Length = 706

 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 44/139 (31%), Positives = 75/139 (53%), Gaps = 5/139 (3%)
 Frame = +3

Query: 591 LSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLALAIRDSERQGKAQVEIVTDG 770
           LSW+SFN  D F+LDLG  +  W G K++  E+ +   L  +++D ER G+AQ+ IV D 
Sbjct: 3   LSWNSFNKDDIFLLDLGNMMIQWNGPKTSTAEKARGLALTRSLKDRERGGRAQIGIVDDE 62

Query: 771 EEPADMIQVLGPKPTLKEGN-----PEEDLTADQKNAQAAALYKVSDATGQMNLNKVADS 935
            E  +++Q++      + GN     P + +   QK   +  +Y V +    +   ++A +
Sbjct: 63  VEAPELMQIMEAVLGRRVGNLRAAMPSKSINEVQK--ASVRIYHVYEKGKDLVFQELA-T 119

Query: 936 SPFAVELLIPDDCFVLDTG 992
            P   +LL  +DC++LD G
Sbjct: 120 CPLTQDLLQKEDCYILDQG 138



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 65/274 (23%), Positives = 108/274 (39%), Gaps = 6/274 (2%)
 Frame = +3

Query: 186  LHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEE---LSHLHLWIGHQSSRDEQGAC 356
            + +W ++      V  ++ G   +G  YLVL+           L+LW G Q++  +  A 
Sbjct: 240  VEVWCIQDSCRQSVDPKHHGQLCAGSCYLVLYTYQRMGLIQYILYLWQGLQAAVHKIKAL 299

Query: 357  AMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSGATPAAI 536
               A  L+ +     VQ     G+E   F++ F   L   +G              P + 
Sbjct: 300  NSNAEELDIMYHGALVQEHVTMGSEPPHFLAIFKGQLVVIQGSAGPI-----GKGQPVSA 354

Query: 537  RKLYQVKGKK--NIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLA 710
             +L+ ++G    N +  E      + N+ D F+L      + W G   +  +R  AR +A
Sbjct: 355  TRLFHIQGTDSCNTQTMEVPARASALNSNDIFLLVTAGLCYLWFGKGCSGDQREMARTVA 414

Query: 711  LAIRDSERQGKAQVEIVTDGEEPADMIQVL-GPKPTLKEGNPEEDLTADQKNAQAAALYK 887
              I    +      E+V +G+EP    + L GP P        ED++  Q       L++
Sbjct: 415  TVISMKNQ------EMVLEGQEPPHFWEALGGPAPYSSSKRLPEDVSDFQPR-----LFE 463

Query: 888  VSDATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
             S  TG   L +V     F+ E L   D  +LDT
Sbjct: 464  CSCQTGPPVLTEVVF---FSQEDLDKYDVMLLDT 494


  Database: RefSeq49_SP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 11,343,932
  Number of sequences in database:  24,897
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 24897
Number of Hits to DB: 27,770,000
Number of extensions: 874619
Number of successful extensions: 4109
Number of sequences better than 1.0e-05: 11
Number of HSP's gapped: 4065
Number of HSP's successfully gapped: 15
Length of query: 333
Length of database: 11,343,932
Length adjustment: 99
Effective length of query: 234
Effective length of database: 8,879,129
Effective search space: 2077716186
Effective search space used: 2077716186
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 34 (17.7 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007642
         (999 letters)

Database: RefSeq49_HP.fasta 
           32,964 sequences; 18,297,164 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_001738.2| macrophage-capping protein [Homo sapiens].           549   e-156
Alignment   gi|NP_001106177.1| adseverin isoform 1 [Homo sapiens].               263   1e-70
Alignment   gi|NP_000168.1| gelsolin isoform a precursor [Homo sapiens].         262   4e-70
Alignment   gi|NP_001121139.1| gelsolin isoform c [Homo sapiens].                262   4e-70
Alignment   gi|NP_001121138.1| gelsolin isoform c [Homo sapiens].                262   4e-70
Alignment   gi|NP_937895.1| gelsolin isoform b [Homo sapiens].                   260   2e-69
Alignment   gi|NP_001121137.1| gelsolin isoform b [Homo sapiens].                260   2e-69
Alignment   gi|NP_001121136.1| gelsolin isoform b [Homo sapiens].                260   2e-69
Alignment   gi|NP_001121135.1| gelsolin isoform b [Homo sapiens].                260   2e-69
Alignment   gi|NP_001121134.1| gelsolin isoform b [Homo sapiens].                260   2e-69

>ref|NP_001738.2| macrophage-capping protein [Homo sapiens].
          Length = 348

 Score =  549 bits (1414), Expect = e-156
 Identities = 268/289 (92%), Positives = 280/289 (96%)
 Frame = +3

Query: 126 MYTSIPQSGSPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSH 305
           MYT+IPQSGSPFP SVQDPGLH+WRVEKLKPVPVA+ENQG+FFSGDSYLVLHNGPEE+SH
Sbjct: 1   MYTAIPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSH 60

Query: 306 LHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 485
           LHLWIG QSSRDEQGACA+LAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG
Sbjct: 61  LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120

Query: 486 VESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCG 665
           VESAFHKTS+GA PAAI+KLYQVKGKKNIRATERAL+WDSFNTGDCFILDLGQNIFAWCG
Sbjct: 121 VESAFHKTSTGA-PAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCG 179

Query: 666 AKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDL 845
            KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPA+MIQVLGPKP LKEGNPEEDL
Sbjct: 180 GKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDL 239

Query: 846 TADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           TAD+ NAQAAALYKVSDATGQMNL KVADSSPFA+ELLI DDCFVLD G
Sbjct: 240 TADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNG 288


>ref|NP_001106177.1| adseverin isoform 1 [Homo sapiens].
          Length = 715

 Score =  263 bits (673), Expect = 1e-70
 Identities = 128/282 (45%), Positives = 188/282 (66%), Gaps = 3/282 (1%)
 Frame = +3

Query: 159 FPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELS---HLHLWIGHQ 329
           F  + +  GL +WR+EKL+ VPV +   G F+ GD+YLVLH          HLH W+G +
Sbjct: 10  FARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWLGKE 69

Query: 330 SSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKT 509
            S+DE  A A+  V ++  LG +PVQ+RE+QG ES+ F+SYF  GLKY+ GGV S  +  
Sbjct: 70  CSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGLNHV 129

Query: 510 SSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILER 689
            +    A  ++L  VKG++ +RATE  LSWDSFN GDCFI+DLG  I+ WCG+  N  ER
Sbjct: 130 LTNDLTA--KRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYER 187

Query: 690 NKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQ 869
            KA  +A  IR +ER+G++++ +V +G EP+++I+VLG KP L +G  ++D+ AD  N +
Sbjct: 188 LKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISNRK 247

Query: 870 AAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTGS 995
            A LY VSDA+G M +  VA+ +PF++ +L+ ++CF+LD G+
Sbjct: 248 MAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGA 289



 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 77/273 (28%), Positives = 120/273 (43%), Gaps = 6/273 (2%)
 Frame = +3

Query: 186  LHIWRVEKLKPVPVARENQGIFFSGDSYLVLHNGPEELSHLHLWIGHQSSRDEQGACAML 365
            + IWRVE    + V + + G F+ GD Y++L+  P     ++ W G  ++RDE    A L
Sbjct: 398  VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYPRG-QIIYTWQGANATRDELTTSAFL 456

Query: 366  AVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIRK 542
             V L+  LG + VQ R  QG E    +S F  + L   + G          G  PA   +
Sbjct: 457  TVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSK-----KGGQAPAPPTR 511

Query: 543  LYQVKGKKNIRATERALSWD----SFNTGDCFILDLGQNI-FAWCGAKSNILERNKARDL 707
            L+QV  ++N+ +  R +  D    S N+ D F+L L QN  + W G  ++  E   A  +
Sbjct: 512  LFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYV 569

Query: 708  ALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYK 887
            A  +       K +   + +GEEP +    LG K   +       L   Q       LY 
Sbjct: 570  ASVL-------KCKTLRIQEGEEPEEFWNSLGGKKDYQ----TSPLLETQAEDHPPRLYG 618

Query: 888  VSDATGQMNLNKVADSSPFAVELLIPDDCFVLD 986
             S+ TG+  + ++     F  + L  DD  +LD
Sbjct: 619  CSNKTGRFVIEEI--PGEFTQDDLAEDDVMLLD 649


>ref|NP_000168.1| gelsolin isoform a precursor [Homo sapiens].
          Length = 782

 Score =  262 bits (669), Expect = 4e-70
 Identities = 141/296 (47%), Positives = 186/296 (62%), Gaps = 5/296 (1%)
 Frame = +3

Query: 120 NSMYTSIPQSGSPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HN 284
           NSM    P+    F  + ++PGL IWRVEK   VPV     G FF+GD+Y++L      N
Sbjct: 50  NSMVVEHPE----FLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRN 105

Query: 285 GPEELSHLHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRG 464
           G  +   LH W+G++ S+DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  G
Sbjct: 106 GNLQYD-LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSG 164

Query: 465 LKYQEGGVESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQ 644
           LKY++GGV S F           +++L+QVKG++ +RATE  +SW+SFN GDCFILDLG 
Sbjct: 165 LKYKKGGVASGFKHVVPNEV--VVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGN 222

Query: 645 NIFAWCGAKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKE 824
           NI  WCG+ SN  ER KA  ++  IRD+ER G+A+V +  +G EP  M+QVLGPKP L  
Sbjct: 223 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPA 282

Query: 825 GNPEEDLTADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           G  E+    D  N + A LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 283 GT-EDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHG 337



 Score =  102 bits (253), Expect = 7e-22
 Identities = 83/272 (30%), Positives = 121/272 (44%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
            IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 449  IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 508

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L   L+  LG  PVQ R VQG E    MS F  + +   +GG          G T  A  
Sbjct: 509  LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGT-----SREGGQTAPAST 563

Query: 540  KLYQVKGKK--NIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
            +L+QV+       RA E      + N+ D F+L      + W G  ++  E+  A++L  
Sbjct: 564  RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLR 623

Query: 714  AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
             +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 624  VLR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFACS 673

Query: 894  DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            +  G+  + +V        E L  DD  +LDT
Sbjct: 674  NKIGRFVIEEV--PGELMQEDLATDDVMLLDT 703


>ref|NP_001121139.1| gelsolin isoform c [Homo sapiens].
          Length = 742

 Score =  262 bits (669), Expect = 4e-70
 Identities = 141/296 (47%), Positives = 186/296 (62%), Gaps = 5/296 (1%)
 Frame = +3

Query: 120 NSMYTSIPQSGSPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HN 284
           NSM    P+    F  + ++PGL IWRVEK   VPV     G FF+GD+Y++L      N
Sbjct: 10  NSMVVEHPE----FLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRN 65

Query: 285 GPEELSHLHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRG 464
           G  +   LH W+G++ S+DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  G
Sbjct: 66  GNLQYD-LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSG 124

Query: 465 LKYQEGGVESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQ 644
           LKY++GGV S F           +++L+QVKG++ +RATE  +SW+SFN GDCFILDLG 
Sbjct: 125 LKYKKGGVASGFKHVVPNEV--VVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGN 182

Query: 645 NIFAWCGAKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKE 824
           NI  WCG+ SN  ER KA  ++  IRD+ER G+A+V +  +G EP  M+QVLGPKP L  
Sbjct: 183 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPA 242

Query: 825 GNPEEDLTADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           G  E+    D  N + A LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 243 GT-EDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHG 297



 Score =  102 bits (253), Expect = 7e-22
 Identities = 83/272 (30%), Positives = 121/272 (44%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
            IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 409  IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 468

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L   L+  LG  PVQ R VQG E    MS F  + +   +GG          G T  A  
Sbjct: 469  LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGT-----SREGGQTAPAST 523

Query: 540  KLYQVKGKK--NIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
            +L+QV+       RA E      + N+ D F+L      + W G  ++  E+  A++L  
Sbjct: 524  RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLR 583

Query: 714  AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
             +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 584  VLR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFACS 633

Query: 894  DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            +  G+  + +V        E L  DD  +LDT
Sbjct: 634  NKIGRFVIEEV--PGELMQEDLATDDVMLLDT 663


>ref|NP_001121138.1| gelsolin isoform c [Homo sapiens].
          Length = 742

 Score =  262 bits (669), Expect = 4e-70
 Identities = 141/296 (47%), Positives = 186/296 (62%), Gaps = 5/296 (1%)
 Frame = +3

Query: 120 NSMYTSIPQSGSPFPASVQDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HN 284
           NSM    P+    F  + ++PGL IWRVEK   VPV     G FF+GD+Y++L      N
Sbjct: 10  NSMVVEHPE----FLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRN 65

Query: 285 GPEELSHLHLWIGHQSSRDEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRG 464
           G  +   LH W+G++ S+DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  G
Sbjct: 66  GNLQYD-LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSG 124

Query: 465 LKYQEGGVESAFHKTSSGATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQ 644
           LKY++GGV S F           +++L+QVKG++ +RATE  +SW+SFN GDCFILDLG 
Sbjct: 125 LKYKKGGVASGFKHVVPNEV--VVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGN 182

Query: 645 NIFAWCGAKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKE 824
           NI  WCG+ SN  ER KA  ++  IRD+ER G+A+V +  +G EP  M+QVLGPKP L  
Sbjct: 183 NIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPA 242

Query: 825 GNPEEDLTADQKNAQAAALYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           G  E+    D  N + A LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 243 GT-EDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHG 297



 Score =  102 bits (253), Expect = 7e-22
 Identities = 83/272 (30%), Positives = 121/272 (44%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
            IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 409  IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 468

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L   L+  LG  PVQ R VQG E    MS F  + +   +GG          G T  A  
Sbjct: 469  LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGT-----SREGGQTAPAST 523

Query: 540  KLYQVKGKK--NIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
            +L+QV+       RA E      + N+ D F+L      + W G  ++  E+  A++L  
Sbjct: 524  RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLR 583

Query: 714  AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
             +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 584  VLR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFACS 633

Query: 894  DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            +  G+  + +V        E L  DD  +LDT
Sbjct: 634  NKIGRFVIEEV--PGELMQEDLATDDVMLLDT 663


>ref|NP_937895.1| gelsolin isoform b [Homo sapiens].
          Length = 731

 Score =  260 bits (664), Expect = 2e-69
 Identities = 136/278 (48%), Positives = 179/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL IWRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G++ S+
Sbjct: 13  KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 71

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 72  DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 131

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SW+SFN GDCFILDLG NI  WCG+ SN  ER KA
Sbjct: 132 EV--VVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKA 189

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+A+V +  +G EP  M+QVLGPKP L  G  E+    D  N + A 
Sbjct: 190 TQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAK 248

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHG 286



 Score =  102 bits (253), Expect = 7e-22
 Identities = 83/272 (30%), Positives = 121/272 (44%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
            IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 398  IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 457

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L   L+  LG  PVQ R VQG E    MS F  + +   +GG          G T  A  
Sbjct: 458  LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGT-----SREGGQTAPAST 512

Query: 540  KLYQVKGKK--NIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
            +L+QV+       RA E      + N+ D F+L      + W G  ++  E+  A++L  
Sbjct: 513  RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLR 572

Query: 714  AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
             +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 573  VLR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFACS 622

Query: 894  DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            +  G+  + +V        E L  DD  +LDT
Sbjct: 623  NKIGRFVIEEV--PGELMQEDLATDDVMLLDT 652


>ref|NP_001121137.1| gelsolin isoform b [Homo sapiens].
          Length = 731

 Score =  260 bits (664), Expect = 2e-69
 Identities = 136/278 (48%), Positives = 179/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL IWRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G++ S+
Sbjct: 13  KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 71

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 72  DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 131

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SW+SFN GDCFILDLG NI  WCG+ SN  ER KA
Sbjct: 132 EV--VVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKA 189

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+A+V +  +G EP  M+QVLGPKP L  G  E+    D  N + A 
Sbjct: 190 TQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAK 248

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHG 286



 Score =  102 bits (253), Expect = 7e-22
 Identities = 83/272 (30%), Positives = 121/272 (44%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
            IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 398  IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 457

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L   L+  LG  PVQ R VQG E    MS F  + +   +GG          G T  A  
Sbjct: 458  LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGT-----SREGGQTAPAST 512

Query: 540  KLYQVKGKK--NIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
            +L+QV+       RA E      + N+ D F+L      + W G  ++  E+  A++L  
Sbjct: 513  RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLR 572

Query: 714  AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
             +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 573  VLR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFACS 622

Query: 894  DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            +  G+  + +V        E L  DD  +LDT
Sbjct: 623  NKIGRFVIEEV--PGELMQEDLATDDVMLLDT 652


>ref|NP_001121136.1| gelsolin isoform b [Homo sapiens].
          Length = 731

 Score =  260 bits (664), Expect = 2e-69
 Identities = 136/278 (48%), Positives = 179/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL IWRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G++ S+
Sbjct: 13  KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 71

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 72  DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 131

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SW+SFN GDCFILDLG NI  WCG+ SN  ER KA
Sbjct: 132 EV--VVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKA 189

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+A+V +  +G EP  M+QVLGPKP L  G  E+    D  N + A 
Sbjct: 190 TQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAK 248

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHG 286



 Score =  102 bits (253), Expect = 7e-22
 Identities = 83/272 (30%), Positives = 121/272 (44%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
            IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 398  IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 457

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L   L+  LG  PVQ R VQG E    MS F  + +   +GG          G T  A  
Sbjct: 458  LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGT-----SREGGQTAPAST 512

Query: 540  KLYQVKGKK--NIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
            +L+QV+       RA E      + N+ D F+L      + W G  ++  E+  A++L  
Sbjct: 513  RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLR 572

Query: 714  AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
             +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 573  VLR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFACS 622

Query: 894  DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            +  G+  + +V        E L  DD  +LDT
Sbjct: 623  NKIGRFVIEEV--PGELMQEDLATDDVMLLDT 652


>ref|NP_001121135.1| gelsolin isoform b [Homo sapiens].
          Length = 731

 Score =  260 bits (664), Expect = 2e-69
 Identities = 136/278 (48%), Positives = 179/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL IWRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G++ S+
Sbjct: 13  KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 71

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 72  DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 131

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SW+SFN GDCFILDLG NI  WCG+ SN  ER KA
Sbjct: 132 EV--VVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKA 189

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+A+V +  +G EP  M+QVLGPKP L  G  E+    D  N + A 
Sbjct: 190 TQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAK 248

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHG 286



 Score =  102 bits (253), Expect = 7e-22
 Identities = 83/272 (30%), Positives = 121/272 (44%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
            IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 398  IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 457

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L   L+  LG  PVQ R VQG E    MS F  + +   +GG          G T  A  
Sbjct: 458  LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGT-----SREGGQTAPAST 512

Query: 540  KLYQVKGKK--NIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
            +L+QV+       RA E      + N+ D F+L      + W G  ++  E+  A++L  
Sbjct: 513  RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLR 572

Query: 714  AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
             +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 573  VLR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFACS 622

Query: 894  DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            +  G+  + +V        E L  DD  +LDT
Sbjct: 623  NKIGRFVIEEV--PGELMQEDLATDDVMLLDT 652


>ref|NP_001121134.1| gelsolin isoform b [Homo sapiens].
          Length = 731

 Score =  260 bits (664), Expect = 2e-69
 Identities = 136/278 (48%), Positives = 179/278 (64%), Gaps = 5/278 (1%)
 Frame = +3

Query: 174 QDPGLHIWRVEKLKPVPVARENQGIFFSGDSYLVL-----HNGPEELSHLHLWIGHQSSR 338
           ++PGL IWRVEK   VPV     G FF+GD+Y++L      NG  +   LH W+G++ S+
Sbjct: 13  KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 71

Query: 339 DEQGACAMLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSSG 518
           DE GA A+  V L+  L  R VQHREVQG ES  F+ YF  GLKY++GGV S F      
Sbjct: 72  DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPN 131

Query: 519 ATPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKA 698
                +++L+QVKG++ +RATE  +SW+SFN GDCFILDLG NI  WCG+ SN  ER KA
Sbjct: 132 EV--VVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKA 189

Query: 699 RDLALAIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAA 878
             ++  IRD+ER G+A+V +  +G EP  M+QVLGPKP L  G  E+    D  N + A 
Sbjct: 190 TQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAK 248

Query: 879 LYKVSDATGQMNLNKVADSSPFAVELLIPDDCFVLDTG 992
           LYKVS+  G M+++ VAD +PFA   L  +DCF+LD G
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHG 286



 Score =  102 bits (253), Expect = 7e-22
 Identities = 83/272 (30%), Positives = 121/272 (44%), Gaps = 6/272 (2%)
 Frame = +3

Query: 192  IWRVEKLKPVPVARENQGIFFSGDSYLVLHN---GPEELSHLHLWIGHQSSRDEQGACAM 362
            IWR+E    VPV     G F+ GDSY++L+N   G  +   ++ W G QS++DE  A A+
Sbjct: 398  IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 457

Query: 363  LAVHLNTLLGERPVQHREVQGNESDLFMSYF-PRGLKYQEGGVESAFHKTSSGATPAAIR 539
            L   L+  LG  PVQ R VQG E    MS F  + +   +GG          G T  A  
Sbjct: 458  LTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGT-----SREGGQTAPAST 512

Query: 540  KLYQVKGKK--NIRATERALSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLAL 713
            +L+QV+       RA E      + N+ D F+L      + W G  ++  E+  A++L  
Sbjct: 513  RLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLR 572

Query: 714  AIRDSERQGKAQVEIVTDGEEPADMIQVLGPKPTLKEGNPEEDLTADQKNAQAAALYKVS 893
             +R       AQ   V +G EP    + LG K   +     +D   D   A    L+  S
Sbjct: 573  VLR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMD---AHPPRLFACS 622

Query: 894  DATGQMNLNKVADSSPFAVELLIPDDCFVLDT 989
            +  G+  + +V        E L  DD  +LDT
Sbjct: 623  NKIGRFVIEEV--PGELMQEDLATDDVMLLDT 652


  Database: RefSeq49_HP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,297,164
  Number of sequences in database:  32,964
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 32964
Number of Hits to DB: 43,767,005
Number of extensions: 1346014
Number of successful extensions: 6203
Number of sequences better than 1.0e-05: 17
Number of HSP's gapped: 6102
Number of HSP's successfully gapped: 29
Length of query: 333
Length of database: 18,297,164
Length adjustment: 103
Effective length of query: 230
Effective length of database: 14,901,872
Effective search space: 3427430560
Effective search space used: 3427430560
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 34 (17.7 bits)

BLASTN 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007642
         (999 letters)

Database: Sscrofa_10.2.fasta 
           4582 sequences; 2,808,509,378 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Sscrofa_Chr03                                                         343   1e-91

>Sscrofa_Chr03 
||          Length = 144787322

 Score =  343 bits (173), Expect = 1e-91
 Identities = 179/181 (98%)
 Strand = Plus / Minus

                                                                            
Query: 142      cccagagcggctctccgttcccagcctcggtgcaggatcccggcctgcacatatggcggg 201
                |||| |||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Sbjct: 62366926 cccacagcggctctccgttcccagcctcggtgcaggatcccggcctgtacatatggcggg 62366867

                                                                            
Query: 202      tggagaagttaaagcccgtgccggtggcccgtgagaaccagggcatcttcttctccggag 261
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 62366866 tggagaagttaaagcccgtgccggtggcccgtgagaaccagggcatcttcttctccggag 62366807

                                                                            
Query: 262      actcctacctggtgctgcacaatggcccggaagagctctcccacctgcacctgtggatag 321
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 62366806 actcctacctggtgctgcacaatggcccggaagagctctcccacctgcacctgtggatag 62366747

                 
Query: 322      g 322
                |
Sbjct: 62366746 g 62366746



 Score =  339 bits (171), Expect = 2e-90
 Identities = 171/171 (100%)
 Strand = Plus / Minus

                                                                            
Query: 474      caggaaggcggtgtggagtcagcatttcacaagacctcctccggggccaccccagctgcc 533
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 62366298 caggaaggcggtgtggagtcagcatttcacaagacctcctccggggccaccccagctgcc 62366239

                                                                            
Query: 534      atcaggaaactctaccaggtgaaggggaagaagaacatccgtgccactgagcgggcgctg 593
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 62366238 atcaggaaactctaccaggtgaaggggaagaagaacatccgtgccactgagcgggcgctg 62366179

                                                                   
Query: 594      agctgggacagcttcaacacaggggactgcttcatcctggacctgggccag 644
                |||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 62366178 agctgggacagcttcaacacaggggactgcttcatcctggacctgggccag 62366128



 Score =  313 bits (158), Expect = 1e-82
 Identities = 158/158 (100%)
 Strand = Plus / Minus

                                                                            
Query: 320      aggccatcagtcatctcgggatgagcagggggcctgcgccatgctggctgtgcacctcaa 379
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 62366651 aggccatcagtcatctcgggatgagcagggggcctgcgccatgctggctgtgcacctcaa 62366592

                                                                            
Query: 380      caccctgcttggggagcggcccgtgcagcaccgagaggtgcagggcaatgagtccgacct 439
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 62366591 caccctgcttggggagcggcccgtgcagcaccgagaggtgcagggcaatgagtccgacct 62366532

                                                      
Query: 440      cttcatgagctacttcccacgaggcctcaagtaccagg 477
                ||||||||||||||||||||||||||||||||||||||
Sbjct: 62366531 cttcatgagctacttcccacgaggcctcaagtaccagg 62366494



 Score =  309 bits (156), Expect = 2e-81
 Identities = 156/156 (100%)
 Strand = Plus / Minus

                                                                            
Query: 641      ccagaacatctttgcctggtgtggtgcaaaatccaacatcctggagcgtaacaaagcgcg 700
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 62364347 ccagaacatctttgcctggtgtggtgcaaaatccaacatcctggagcgtaacaaagcgcg 62364288

                                                                            
Query: 701      ggacctggccctggccatccgggacagtgagcggcagggcaaggcccaggtggagattgt 760
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 62364287 ggacctggccctggccatccgggacagtgagcggcagggcaaggcccaggtggagattgt 62364228

                                                    
Query: 761      cactgacggggaggagcctgcagacatgatccaggt 796
                ||||||||||||||||||||||||||||||||||||
Sbjct: 62364227 cactgacggggaggagcctgcagacatgatccaggt 62364192



 Score =  204 bits (103), Expect = 7e-50
 Identities = 113/115 (98%), Gaps = 1/115 (0%)
 Strand = Plus / Minus

                                                                            
Query: 886      aggtctctgatgccactggacagatgaacctgaacaaggtggccgactccagcccctttg 945
                ||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
Sbjct: 62363285 aggtctctgatgccactggacagatgaacctgaccaaggtggccgactccagcccctttg 62363226

                                                                       
Query: 946      ccgttgagctgctgatacctgacgactgctttgtgttggac-acgggctctgtgg 999
                ||||||||||||||||||||||||||||||||||||||||| |||||||||||||
Sbjct: 62363225 ccgttgagctgctgatacctgacgactgctttgtgttggacaacgggctctgtgg 62363171



 Score =  194 bits (98), Expect = 6e-47
 Identities = 98/98 (100%)
 Strand = Plus / Minus

                                                                            
Query: 792      caggtcctgggccccaagcctactctgaaggagggcaaccccgaggaagacctcacagct 851
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 62363837 caggtcctgggccccaagcctactctgaaggagggcaaccccgaggaagacctcacagct 62363778

                                                      
Query: 852      gaccagaaaaatgcccaggccgcggctctgtacaaggt 889
                ||||||||||||||||||||||||||||||||||||||
Sbjct: 62363777 gaccagaaaaatgcccaggccgcggctctgtacaaggt 62363740



 Score =  115 bits (58), Expect = 5e-23
 Identities = 58/58 (100%)
 Strand = Plus / Minus

                                                                          
Query: 1        gggtggcagacactgtggcagacactgtggtccaagtaacacagcggagcgtaggcag 58
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 62374543 gggtggcagacactgtggcagacactgtggtccaagtaacacagcggagcgtaggcag 62374486



 Score =  113 bits (57), Expect = 2e-22
 Identities = 57/57 (100%)
 Strand = Plus / Minus

                                                                         
Query: 56       cagatagggcacaaggaggctccagcaagttgtcacttgccagaggaagcgcagcta 112
                |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 62373748 cagatagggcacaaggaggctccagcaagttgtcacttgccagaggaagcgcagcta 62373692



 Score = 71.9 bits (36), Expect = 6e-10
 Identities = 36/36 (100%)
 Strand = Plus / Minus

                                                    
Query: 113      atctggaaacagcatgtacacatccatcccccagag 148
                ||||||||||||||||||||||||||||||||||||
Sbjct: 62367116 atctggaaacagcatgtacacatccatcccccagag 62367081


  Database: Sscrofa_10.2.fasta
    Posted date:  Nov 16, 2011 10:34 AM
  Number of letters in database: 2,808,509,378
  Number of sequences in database:  4582
  
Lambda     K      H
    1.37    0.711     1.31 

Gapped
Lambda     K      H
    1.37    0.711     1.31 


Matrix: blastn matrix:1 -3
Gap Penalties: Existence: 5, Extension: 2
Number of Sequences: 4582
Number of Hits to DB: 26,065,569
Number of extensions: 131
Number of successful extensions: 131
Number of sequences better than 1.0e-05: 1
Number of HSP's gapped: 131
Number of HSP's successfully gapped: 9
Length of query: 999
Length of database: 2,808,509,378
Length adjustment: 21
Effective length of query: 978
Effective length of database: 2,808,413,156
Effective search space: 2746628066568
Effective search space used: 2746628066568
X1: 11 (21.8 bits)
X2: 15 (29.7 bits)
X3: 50 (99.1 bits)
S1: 18 (36.2 bits)
S2: 29 (58.0 bits)