Animal-Genome cDNA 20110601C-007857

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007857
         (1040 letters)

Database: RefSeq49_BP.fasta 
           33,088 sequences; 17,681,374 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_001029410.1| protein phosphatase 1 regulatory subunit 7 [...   530   e-151
Alignment   gi|NP_001093813.1| leucine-rich repeat-containing protein 49 [B...   101   9e-22
Alignment   gi|NP_001178064.1| leucine-rich repeat and IQ domain-containing...    89   5e-18
Alignment   gi|XP_002687239.1| PREDICTED: leucine-rich repeats and IQ motif...    89   5e-18
Alignment   gi|NP_001179353.1| centrosomal protein of 97 kDa [Bos taurus].        87   2e-17
Alignment   gi|NP_001095581.1| leucine-rich repeat-containing protein 48 [B...    87   2e-17
Alignment   gi|XP_002684770.1| PREDICTED: centrosomal protein 97-like [Bos ...    87   2e-17
Alignment   gi|XP_002691063.1| PREDICTED: Leucine-rich repeat-containing pr...    85   1e-16
Alignment   gi|XP_002700698.1| PREDICTED: Leucine-rich repeat-containing pr...    85   1e-16
Alignment   gi|NP_001179616.1| leucine-rich repeat and guanylate kinase dom...    84   2e-16

>ref|NP_001029410.1| protein phosphatase 1 regulatory subunit 7 [Bos taurus].
          Length = 360

 Score =  530 bits (1365), Expect = e-151
 Identities = 278/335 (82%), Positives = 293/335 (87%)
 Frame = +1

Query: 31   MAAERGTGQQQSQEMMEVDRRVXXXXXXXXXXXXXXXXIVADLSEHSLKDXXXXXXXXXX 210
            MAAERG GQQQSQEMMEVDRRV                +VADLS HSLKD          
Sbjct: 1    MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKQNSGMVADLSAHSLKDGEERGDEDPE 60

Query: 211  XXXXXXVDMETINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQ 390
                  VDMETI+LDRDAEDVDLNHYRIGKIEGFEVL+KVKTLCLRQNLIKCIENLE LQ
Sbjct: 61   EGQELPVDMETISLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEGLQ 120

Query: 391  SLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIE 570
            SLRELDLYDNQIR+IENL+ALTELE+LDISFNLLR+IEG+DKLTRLKKLFLVNNKINKIE
Sbjct: 121  SLRELDLYDNQIRRIENLDALTELEVLDISFNLLRNIEGIDKLTRLKKLFLVNNKINKIE 180

Query: 571  NLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 750
            N+SSL QLQMLELGSNRIRAIEN+DTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN
Sbjct: 181  NISSLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 240

Query: 751  RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQE 930
            RLTKIEGLQSLVNLRELYLSHNGIEVIEGLD+NNKLTMLDIASNRIKKIENVSHLTELQE
Sbjct: 241  RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDNNNKLTMLDIASNRIKKIENVSHLTELQE 300

Query: 931  FWMNDNLLESWSDLX*AQGAQSLETVYLERTPCRR 1035
            FWMNDNLL+ WSDL   +GA+SLETVYLER P +R
Sbjct: 301  FWMNDNLLDCWSDLDELKGARSLETVYLERNPLQR 335



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 40/111 (36%), Positives = 60/111 (54%)
 Frame = +1

Query: 289 RIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEI 468
           R+ KIEG + L  ++ L L  N I+ IE L+    L  LD+  N+I+KIEN+  LTEL+ 
Sbjct: 241 RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDNNNKLTMLDIASNRIKKIENVSHLTELQE 300

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNR 621
             ++ NLL     +D+L   + L  V  + N ++     R+  ML L S R
Sbjct: 301 FWMNDNLLDCWSDLDELKGARSLETVYLERNPLQRDPQYRRKIMLALPSVR 351


>ref|NP_001093813.1| leucine-rich repeat-containing protein 49 [Bos taurus].
          Length = 685

 Score =  101 bits (252), Expect = 9e-22
 Identities = 68/212 (32%), Positives = 109/212 (51%), Gaps = 3/212 (1%)
 Frame = +1

Query: 346 RQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTR 525
           RQ L  C   ++  + LR L+   N I +I+N+  L  L  LD+  N +  I G+  L  
Sbjct: 99  RQKLTVC-PIIDGEEHLRLLNFQHNSITQIQNISNLQRLIFLDLYDNQIEEISGLSTLRS 157

Query: 526 LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
           L+ L L  N+I KI NL +L+ L +L+L  N+I  IENV+ L +L  L L +N ++ + N
Sbjct: 158 LRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENVNHLCDLRVLNLARNFLSHVDN 217

Query: 706 LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEG---LDSNNKLTMLDIA 876
           L+ L +LT L+++ N++T +  + +L  L+ L+LS N I   E    L  +  L+ +   
Sbjct: 218 LNGLDSLTELNLRHNQITFVRDVDNLPCLQRLFLSFNNISTFESVCCLADSTSLSDITFD 277

Query: 877 SNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            N I            QE W    +L++   L
Sbjct: 278 GNPI-----------AQESWYKHTILQNMMQL 298



 Score =  100 bits (249), Expect = 2e-21
 Identities = 56/173 (32%), Positives = 100/173 (57%)
 Frame = +1

Query: 508  VDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNK 687
            +D    L+ L   +N I +I+N+S+L++L  L+L  N+I  I  + TL +L  L LGKN+
Sbjct: 108  IDGEEHLRLLNFQHNSITQIQNISNLQRLIFLDLYDNQIEEISGLSTLRSLRVLLLGKNR 167

Query: 688  ITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTML 867
            I K+ NL+ L +L VL +  N++TKIE +  L +LR L L+ N +  ++ L+  + LT L
Sbjct: 168  IKKISNLENLKSLDVLDLHGNQITKIENVNHLCDLRVLNLARNFLSHVDNLNGLDSLTEL 227

Query: 868  DIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERTP 1026
            ++  N+I  + +V +L  LQ  +++ N + ++  +     + SL  +  +  P
Sbjct: 228  NLRHNQITFVRDVDNLPCLQRLFLSFNNISTFESVCCLADSTSLSDITFDGNP 280



 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 63/185 (34%), Positives = 102/185 (55%), Gaps = 8/185 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           ++  H  I +I+    L+++  L L  N I+ I  L  L+SLR L L  N+I+KI NLE 
Sbjct: 117 LNFQHNSITQIQNISNLQRLIFLDLYDNQIEEISGLSTLRSLRVLLLGKNRIKKISNLEN 176

Query: 451 LTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRA 630
           L  L++LD+  N +  IE V+ L  L+ L L  N ++ ++NL+ L  L  L L  N+I  
Sbjct: 177 LKSLDVLDLHGNQITKIENVNHLCDLRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITF 236

Query: 631 IENVDTLTNLESLFLGKNKITKLQNLDAL---TNLTVLSMQSNRLT-----KIEGLQSLV 786
           + +VD L  L+ LFL  N I+  +++  L   T+L+ ++   N +      K   LQ+++
Sbjct: 237 VRDVDNLPCLQRLFLSFNNISTFESVCCLADSTSLSDITFDGNPIAQESWYKHTILQNMM 296

Query: 787 NLREL 801
            LR+L
Sbjct: 297 QLRQL 301



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 42/124 (33%), Positives = 66/124 (53%)
 Frame = +1

Query: 601 LELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQS 780
           L L   ++     +D   +L  L    N IT++QN+  L  L  L +  N++ +I GL +
Sbjct: 95  LTLERQKLTVCPIIDGEEHLRLLNFQHNSITQIQNISNLQRLIFLDLYDNQIEEISGLST 154

Query: 781 LVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
           L +LR L L  N I+ I  L++   L +LD+  N+I KIENV+HL +L+   +  N L  
Sbjct: 155 LRSLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENVNHLCDLRVLNLARNFLSH 214

Query: 961 WSDL 972
             +L
Sbjct: 215 VDNL 218



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 47/154 (30%), Positives = 76/154 (49%)
 Frame = +1

Query: 487 LLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLES 666
           L RS E  +K+    +L L   K+     +     L++L    N I  I+N+  L  L  
Sbjct: 81  LQRSSE--EKILYSDRLTLERQKLTVCPIIDGEEHLRLLNFQHNSITQIQNISNLQRLIF 138

Query: 667 LFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDS 846
           L L  N+I ++  L  L +L VL +  NR+ KI  L++L +L  L L  N I  IE ++ 
Sbjct: 139 LDLYDNQIEEISGLSTLRSLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENVNH 198

Query: 847 NNKLTMLDIASNRIKKIENVSHLTELQEFWMNDN 948
              L +L++A N +  ++N++ L  L E  +  N
Sbjct: 199 LCDLRVLNLARNFLSHVDNLNGLDSLTELNLRHN 232


>ref|NP_001178064.1| leucine-rich repeat and IQ domain-containing protein 1 [Bos taurus].
          Length = 1668

 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 63/208 (30%), Positives = 109/208 (52%), Gaps = 2/208 (0%)
 Frame = +1

Query: 337  LCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDK 516
            L LR+  +  + +L   + L+ +D  +N I  I N E L  L I+ ++ N L S+ G+D 
Sbjct: 824  LSLRRCGLTSLHSLSNCKRLKYIDAQENHIETI-NCENLENLCIVLLNKNQLTSLHGLDG 882

Query: 517  LTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITK 696
             T ++ L L +NKI +I  L SL+ LQ L +  N++ +   +     L  L    N +T+
Sbjct: 883  CTNIQSLELSHNKITRIGGLESLKNLQQLIVDHNQLISTTGLCDTPTLMYLDCSHNHLTE 942

Query: 697  LQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSN--NKLTMLD 870
            ++ ++    L +L +Q N L+++  L + V LREL+L  N I  +E   S     L +L 
Sbjct: 943  VEGIEQCGLLQILKLQGNYLSELPFLGNHVLLRELHLDDNSISTVETFSSYWLPLLQILT 1002

Query: 871  IASNRIKKIENVSHLTELQEFWMNDNLL 954
            I+ N + KI  + H   L++  +++N L
Sbjct: 1003 ISQNSLTKIAPLFHFVSLEKLDVSNNCL 1030



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 60/234 (25%), Positives = 107/234 (45%), Gaps = 17/234 (7%)
 Frame = +1

Query: 310  FEVLRK--VKTLCLRQNLIKCIENL---------------EALQSLRELDLYDNQIRKIE 438
            FE+ ++   K +  R+ +IKC  N                + LQ +  +   D     + 
Sbjct: 754  FEIFKQNQQKKIVKRRRIIKCPVNTMPPLNPLEILRCGPWDTLQQVATITFQDLPGCSLS 813

Query: 439  NLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSN 618
             L     L+ L +    L S+  +    RLK +    N I  I N  +L  L ++ L  N
Sbjct: 814  TLAECPNLQFLSLRRCGLTSLHSLSNCKRLKYIDAQENHIETI-NCENLENLCIVLLNKN 872

Query: 619  RIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRE 798
            ++ ++  +D  TN++SL L  NKIT++  L++L NL  L +  N+L    GL     L  
Sbjct: 873  QLTSLHGLDGCTNIQSLELSHNKITRIGGLESLKNLQQLIVDHNQLISTTGLCDTPTLMY 932

Query: 799  LYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
            L  SHN +  +EG++    L +L +  N + ++  + +   L+E  ++DN + +
Sbjct: 933  LDCSHNHLTEVEGIEQCGLLQILKLQGNYLSELPFLGNHVLLRELHLDDNSIST 986



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 57/202 (28%), Positives = 100/202 (49%), Gaps = 8/202 (3%)
 Frame = +1

Query: 235  METINLDR--DAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELD 408
            +ETIN +   +   V LN  ++  + G +    +++L L  N I  I  LE+L++L++L 
Sbjct: 853  IETINCENLENLCIVLLNKNQLTSLHGLDGCTNIQSLELSHNKITRIGGLESLKNLQQLI 912

Query: 409  LYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLR 588
            +  NQ+     L     L  LD S N L  +EG+++   L+ L L  N ++++  L +  
Sbjct: 913  VDHNQLISTTGLCDTPTLMYLDCSHNHLTEVEGIEQCGLLQILKLQGNYLSELPFLGNHV 972

Query: 589  QLQMLELGSNRIRAIENVDT--LTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRL-- 756
             L+ L L  N I  +E   +  L  L+ L + +N +TK+  L    +L  L + +N L  
Sbjct: 973  LLRELHLDDNSISTVETFSSYWLPLLQILTISQNSLTKIAPLFHFVSLEKLDVSNNCLSD 1032

Query: 757  --TKIEGLQSLVNLRELYLSHN 816
              + I+   +  +L EL L+ N
Sbjct: 1033 LTSAIKWFDACFSLHELSLTGN 1054


>ref|XP_002687239.1| PREDICTED: leucine-rich repeats and IQ motif containing 1 [Bos
            taurus].
          Length = 1668

 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 63/208 (30%), Positives = 109/208 (52%), Gaps = 2/208 (0%)
 Frame = +1

Query: 337  LCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDK 516
            L LR+  +  + +L   + L+ +D  +N I  I N E L  L I+ ++ N L S+ G+D 
Sbjct: 824  LSLRRCGLTSLHSLSNCKRLKYIDAQENHIETI-NCENLENLCIVLLNKNQLTSLHGLDG 882

Query: 517  LTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITK 696
             T ++ L L +NKI +I  L SL+ LQ L +  N++ +   +     L  L    N +T+
Sbjct: 883  CTNIQSLELSHNKITRIGGLESLKNLQQLIVDHNQLISTTGLCDTPTLMYLDCSHNHLTE 942

Query: 697  LQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSN--NKLTMLD 870
            ++ ++    L +L +Q N L+++  L + V LREL+L  N I  +E   S     L +L 
Sbjct: 943  VEGIEQCGLLQILKLQGNYLSELPFLGNHVLLRELHLDDNSISTVETFSSYWLPLLQILT 1002

Query: 871  IASNRIKKIENVSHLTELQEFWMNDNLL 954
            I+ N + KI  + H   L++  +++N L
Sbjct: 1003 ISQNSLTKIAPLFHFVSLEKLDVSNNCL 1030



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 60/234 (25%), Positives = 107/234 (45%), Gaps = 17/234 (7%)
 Frame = +1

Query: 310  FEVLRK--VKTLCLRQNLIKCIENL---------------EALQSLRELDLYDNQIRKIE 438
            FE+ ++   K +  R+ +IKC  N                + LQ +  +   D     + 
Sbjct: 754  FEIFKQNQQKKIVKRRRIIKCPVNTMPPLNPLEILRCGPWDTLQQVATITFQDLPGCSLS 813

Query: 439  NLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSN 618
             L     L+ L +    L S+  +    RLK +    N I  I N  +L  L ++ L  N
Sbjct: 814  TLAECPNLQFLSLRRCGLTSLHSLSNCKRLKYIDAQENHIETI-NCENLENLCIVLLNKN 872

Query: 619  RIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRE 798
            ++ ++  +D  TN++SL L  NKIT++  L++L NL  L +  N+L    GL     L  
Sbjct: 873  QLTSLHGLDGCTNIQSLELSHNKITRIGGLESLKNLQQLIVDHNQLISTTGLCDTPTLMY 932

Query: 799  LYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
            L  SHN +  +EG++    L +L +  N + ++  + +   L+E  ++DN + +
Sbjct: 933  LDCSHNHLTEVEGIEQCGLLQILKLQGNYLSELPFLGNHVLLRELHLDDNSIST 986



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 57/202 (28%), Positives = 100/202 (49%), Gaps = 8/202 (3%)
 Frame = +1

Query: 235  METINLDR--DAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELD 408
            +ETIN +   +   V LN  ++  + G +    +++L L  N I  I  LE+L++L++L 
Sbjct: 853  IETINCENLENLCIVLLNKNQLTSLHGLDGCTNIQSLELSHNKITRIGGLESLKNLQQLI 912

Query: 409  LYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLR 588
            +  NQ+     L     L  LD S N L  +EG+++   L+ L L  N ++++  L +  
Sbjct: 913  VDHNQLISTTGLCDTPTLMYLDCSHNHLTEVEGIEQCGLLQILKLQGNYLSELPFLGNHV 972

Query: 589  QLQMLELGSNRIRAIENVDT--LTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRL-- 756
             L+ L L  N I  +E   +  L  L+ L + +N +TK+  L    +L  L + +N L  
Sbjct: 973  LLRELHLDDNSISTVETFSSYWLPLLQILTISQNSLTKIAPLFHFVSLEKLDVSNNCLSD 1032

Query: 757  --TKIEGLQSLVNLRELYLSHN 816
              + I+   +  +L EL L+ N
Sbjct: 1033 LTSAIKWFDACFSLHELSLTGN 1054


>ref|NP_001179353.1| centrosomal protein of 97 kDa [Bos taurus].
          Length = 858

 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 63/194 (32%), Positives = 92/194 (47%)
 Frame = +1

Query: 349 QNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRL 528
           Q L K   NL     +  L L  NQI K+ENLE    L  L ++ N L  + GV KLT+L
Sbjct: 23  QGLQKLSPNLPCEADIHTLILDKNQIIKLENLEKCKRLVQLSVANNRLVRMMGVAKLTQL 82

Query: 529 KKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNL 708
           + L L +N I  +E L  L  L+ L L  N ++A+E ++T T+L+ L L  N I ++ +L
Sbjct: 83  RVLNLPHNSIGYVEGLKELVHLEWLNLAGNNLKAMEQINTCTSLQHLDLSDNNIPQIGDL 142

Query: 709 DALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRI 888
             L +L  L +  N +T +        +   YL                L +L +A N I
Sbjct: 143 SKLVSLKTLLLHGNIITSL-------RMAPAYLP-------------RCLAILSLAENEI 182

Query: 889 KKIENVSHLTELQE 930
           + +  VS L  L E
Sbjct: 183 RDLNEVSFLASLTE 196



 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 41/112 (36%), Positives = 63/112 (56%)
 Frame = +1

Query: 637 NVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHN 816
           N+    ++ +L L KN+I KL+NL+    L  LS+ +NRL ++ G+  L  LR L L HN
Sbjct: 31  NLPCEADIHTLILDKNQIIKLENLEKCKRLVQLSVANNRLVRMMGVAKLTQLRVLNLPHN 90

Query: 817 GIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            I  +EGL     L  L++A N +K +E ++  T LQ   ++DN +    DL
Sbjct: 91  SIGYVEGLKELVHLEWLNLAGNNLKAMEQINTCTSLQHLDLSDNNIPQIGDL 142



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 38/130 (29%), Positives = 72/130 (55%)
 Frame = +1

Query: 571 NLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 750
           NL     +  L L  N+I  +EN++    L  L +  N++ ++  +  LT L VL++  N
Sbjct: 31  NLPCEADIHTLILDKNQIIKLENLEKCKRLVQLSVANNRLVRMMGVAKLTQLRVLNLPHN 90

Query: 751 RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQE 930
            +  +EGL+ LV+L  L L+ N ++ +E +++   L  LD++ N I +I ++S L  L+ 
Sbjct: 91  SIGYVEGLKELVHLEWLNLAGNNLKAMEQINTCTSLQHLDLSDNNIPQIGDLSKLVSLKT 150

Query: 931 FWMNDNLLES 960
             ++ N++ S
Sbjct: 151 LLLHGNIITS 160



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 41/121 (33%), Positives = 66/121 (54%), Gaps = 5/121 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           ++L H  IG +EG + L  ++ L L  N +K +E +    SL+ LDL DN I +I +L  
Sbjct: 85  LNLPHNSIGYVEGLKELVHLEWLNLAGNNLKAMEQINTCTSLQHLDLSDNNIPQIGDLSK 144

Query: 451 LTELEILDISFNLLRSIEGVDK-LTR-LKKLFLVNNKI---NKIENLSSLRQLQMLELGS 615
           L  L+ L +  N++ S+      L R L  L L  N+I   N++  L+SL +L+ L + +
Sbjct: 145 LVSLKTLLLHGNIITSLRMAPAYLPRCLAILSLAENEIRDLNEVSFLASLTELEQLSIMN 204

Query: 616 N 618
           N
Sbjct: 205 N 205


>ref|NP_001095581.1| leucine-rich repeat-containing protein 48 [Bos taurus].
          Length = 522

 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 49/107 (45%), Positives = 74/107 (69%)
 Frame = +1

Query: 349 QNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRL 528
           QN+++ I+NL   +SL++L L +N I KIE LE LT L  LD+SFN + +IEG+D L  L
Sbjct: 52  QNILR-IDNLWQFESLQKLQLDNNIIEKIEGLENLTRLVWLDLSFNNIEAIEGLDTLVNL 110

Query: 529 KKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESL 669
           + L L NN+I+KI++L +L +LQ+L LG+N I  + N+  L   ++L
Sbjct: 111 EDLSLFNNRISKIDSLDALVKLQVLSLGNNHIGNMMNIIYLRRFKAL 157



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 59/174 (33%), Positives = 90/174 (51%), Gaps = 10/174 (5%)
 Frame = +1

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDT 648
           L + F  +  I+ + +   L+KL L NN I KIE L +L +L  L+L  N I AIE +DT
Sbjct: 47  LQLDFQNILRIDNLWQFESLQKLQLDNNIIEKIEGLENLTRLVWLDLSFNNIEAIEGLDT 106

Query: 649 LTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLREL-YLSHNGIE 825
           L NLE L L  N+I+K+ +LDAL  L VLS+ +N +  +  +  L   + L  LS +G  
Sbjct: 107 LVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNHIGNMMNIIYLRRFKALRTLSLSGNP 166

Query: 826 VIEGLDSN-------NKLTMLDI--ASNRIKKIENVSHLTELQEFWMNDNLLES 960
           V E  D           L  LD     + +K++  + H   + E    +NL+++
Sbjct: 167 VAEDEDYKMFICAYLPDLVYLDFRRLDDHMKELAEMKHQYSIDELKHRENLMQA 220



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 42/121 (34%), Positives = 67/121 (55%)
 Frame = +1

Query: 664  SLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLD 843
            SL L    I ++ NL    +L  L + +N + KIEGL++L  L  L LS N IE IEGLD
Sbjct: 46   SLQLDFQNILRIDNLWQFESLQKLQLDNNIIEKIEGLENLTRLVWLDLSFNNIEAIEGLD 105

Query: 844  SNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERT 1023
            +   L  L + +NRI KI+++  L +LQ   + +N + +  ++   +  ++L T+ L   
Sbjct: 106  TLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNHIGNMMNIIYLRRFKALRTLSLSGN 165

Query: 1024 P 1026
            P
Sbjct: 166  P 166



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 3/133 (2%)
 Frame = +1

Query: 250 LDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIR 429
           L +D   + L+   I +I+       ++ L L  N+I+ IE LE L  L  LDL  N I 
Sbjct: 40  LFKDVVSLQLDFQNILRIDNLWQFESLQKLQLDNNIIEKIEGLENLTRLVWLDLSFNNIE 99

Query: 430 KIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQ---LQM 600
            IE L+ L  LE L +  N +  I+ +D L +L+ L L NN I  + N+  LR+   L+ 
Sbjct: 100 AIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNHIGNMMNIIYLRRFKALRT 159

Query: 601 LELGSNRIRAIEN 639
           L L  N +   E+
Sbjct: 160 LSLSGNPVAEDED 172


>ref|XP_002684770.1| PREDICTED: centrosomal protein 97-like [Bos taurus].
          Length = 858

 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 63/194 (32%), Positives = 92/194 (47%)
 Frame = +1

Query: 349 QNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRL 528
           Q L K   NL     +  L L  NQI K+ENLE    L  L ++ N L  + GV KLT+L
Sbjct: 23  QGLQKLSPNLPCEADIHTLILDKNQIIKLENLEKCKRLVQLSVANNRLVRMMGVAKLTQL 82

Query: 529 KKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNL 708
           + L L +N I  +E L  L  L+ L L  N ++A+E ++T T+L+ L L  N I ++ +L
Sbjct: 83  RVLNLPHNSIGYVEGLKELVHLEWLNLAGNNLKAMEQINTCTSLQHLDLSDNNIPQIGDL 142

Query: 709 DALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRI 888
             L +L  L +  N +T +        +   YL                L +L +A N I
Sbjct: 143 SKLVSLKTLLLHGNIITSL-------RMAPAYLP-------------RCLAILSLAENEI 182

Query: 889 KKIENVSHLTELQE 930
           + +  VS L  L E
Sbjct: 183 RDLNEVSFLASLTE 196



 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 41/112 (36%), Positives = 63/112 (56%)
 Frame = +1

Query: 637 NVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHN 816
           N+    ++ +L L KN+I KL+NL+    L  LS+ +NRL ++ G+  L  LR L L HN
Sbjct: 31  NLPCEADIHTLILDKNQIIKLENLEKCKRLVQLSVANNRLVRMMGVAKLTQLRVLNLPHN 90

Query: 817 GIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            I  +EGL     L  L++A N +K +E ++  T LQ   ++DN +    DL
Sbjct: 91  SIGYVEGLKELVHLEWLNLAGNNLKAMEQINTCTSLQHLDLSDNNIPQIGDL 142



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 38/130 (29%), Positives = 72/130 (55%)
 Frame = +1

Query: 571 NLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 750
           NL     +  L L  N+I  +EN++    L  L +  N++ ++  +  LT L VL++  N
Sbjct: 31  NLPCEADIHTLILDKNQIIKLENLEKCKRLVQLSVANNRLVRMMGVAKLTQLRVLNLPHN 90

Query: 751 RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQE 930
            +  +EGL+ LV+L  L L+ N ++ +E +++   L  LD++ N I +I ++S L  L+ 
Sbjct: 91  SIGYVEGLKELVHLEWLNLAGNNLKAMEQINTCTSLQHLDLSDNNIPQIGDLSKLVSLKT 150

Query: 931 FWMNDNLLES 960
             ++ N++ S
Sbjct: 151 LLLHGNIITS 160



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 41/121 (33%), Positives = 66/121 (54%), Gaps = 5/121 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           ++L H  IG +EG + L  ++ L L  N +K +E +    SL+ LDL DN I +I +L  
Sbjct: 85  LNLPHNSIGYVEGLKELVHLEWLNLAGNNLKAMEQINTCTSLQHLDLSDNNIPQIGDLSK 144

Query: 451 LTELEILDISFNLLRSIEGVDK-LTR-LKKLFLVNNKI---NKIENLSSLRQLQMLELGS 615
           L  L+ L +  N++ S+      L R L  L L  N+I   N++  L+SL +L+ L + +
Sbjct: 145 LVSLKTLLLHGNIITSLRMAPAYLPRCLAILSLAENEIRDLNEVSFLASLTELEQLSIMN 204

Query: 616 N 618
           N
Sbjct: 205 N 205


>ref|XP_002691063.1| PREDICTED: Leucine-rich repeat-containing protein 9-like [Bos
           taurus].
          Length = 1538

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 64/201 (31%), Positives = 107/201 (53%), Gaps = 4/201 (1%)
 Frame = +1

Query: 355 LIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKK 534
           +I+C EN+     ++EL L +    ++   E  ++   L++ F+    I G+     L  
Sbjct: 1   MIEC-ENINQHDIIKELCLCNGLSYEMIGQEG-SDTSKLEMFFSGYPRIVGLSLFPNLTS 58

Query: 535 LFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDA 714
           L +V   I +I  L +  QL+ L +    I  I  +    +LE L+L  NKI+K++NL+ 
Sbjct: 59  LTIVAQDIKEISGLETCLQLKELWIAECCIEKIGGLQECRSLEKLYLYYNKISKIENLEK 118

Query: 715 LTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVI-EGLDSNNKLTMLDIASNRI- 888
           L+ L VL +  N +  IEGLQ+L NL +L L+ N I  I   LD N +L  L+++ N+I 
Sbjct: 119 LSRLEVLWLNHNAIKYIEGLQTLKNLSDLNLAGNLISSIGRCLDPNEQLERLNLSGNQIC 178

Query: 889 --KKIENVSHLTELQEFWMND 945
             K + N++ L  L++  +ND
Sbjct: 179 SFKDLTNLTRLRHLKDLCLND 199



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 59/208 (28%), Positives = 100/208 (48%), Gaps = 17/208 (8%)
 Frame = +1

Query: 367 IENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLV 546
           I  L    +L  L +    I++I  LE   +L+ L I+   +  I G+ +   L+KL+L 
Sbjct: 47  IVGLSLFPNLTSLTIVAQDIKEISGLETCLQLKELWIAECCIEKIGGLQECRSLEKLYLY 106

Query: 547 NNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKL-QNLDALTN 723
            NKI+KIENL  L +L++L L  N I+ IE + TL NL  L L  N I+ + + LD    
Sbjct: 107 YNKISKIENLEKLSRLEVLWLNHNAIKYIEGLQTLKNLSDLNLAGNLISSIGRCLDPNEQ 166

Query: 724 LTVLSMQSNRLTKIEGLQSLVNLREL----------------YLSHNGIEVIEGLDSNNK 855
           L  L++  N++   + L +L  LR L                 L +    V+  L    +
Sbjct: 167 LERLNLSGNQICSFKDLTNLTRLRHLKDLCLNDPQYKTNPVCLLCNYSTHVLYHLPCLQR 226

Query: 856 LTMLDIASNRIKKIENVSHLTELQEFWM 939
           L   D++  +IK++ + + + ++  + M
Sbjct: 227 LDTFDVSPKQIKELADTTAMKKIMYYNM 254



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 48/127 (37%), Positives = 72/127 (56%), Gaps = 1/127 (0%)
 Frame = +1

Query: 292 IGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEIL 471
           I +I G E   ++K L + +  I+ I  L+  +SL +L LY N+I KIENLE L+ LE+L
Sbjct: 66  IKEISGLETCLQLKELWIAECCIEKIGGLQECRSLEKLYLYYNKISKIENLEKLSRLEVL 125

Query: 472 DISFNLLRSIEGVDKLTRLKKLFLVNNKINKIEN-LSSLRQLQMLELGSNRIRAIENVDT 648
            ++ N ++ IEG+  L  L  L L  N I+ I   L    QL+ L L  N+I + +++  
Sbjct: 126 WLNHNAIKYIEGLQTLKNLSDLNLAGNLISSIGRCLDPNEQLERLNLSGNQICSFKDLTN 185

Query: 649 LTNLESL 669
           LT L  L
Sbjct: 186 LTRLRHL 192



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 55/168 (32%), Positives = 84/168 (50%), Gaps = 11/168 (6%)
 Frame = +1

Query: 457  ELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIE 636
            ++  L++    L  I  ++KL  LK     NN + K+E L S   L+ L L  N I  IE
Sbjct: 888  KITALNLDGQHLFEITNLEKLENLKWASFSNNNLTKMEGLESCVNLEELTLDGNCISKIE 947

Query: 637  NVDTLTNLESLFLGKNKITKLQN--LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLS 810
             +  LT L  L +  N +T L+    D + +L  LS+++NR+T + GLQ    L ELY+S
Sbjct: 948  GISKLTKLTHLSINNNLLTGLEKHIFDNMLHLHSLSLENNRITSLSGLQKAFTLIELYVS 1007

Query: 811  HNGI---EVIEGLDSNNKLTMLDIASNRI------KKIENVSHLTELQ 927
            +N I   + I  L     L +LD+  N I       ++  + HL EL+
Sbjct: 1008 NNYIALNQEIYNLKGLCNLVILDMYGNIIVWNQENYRLFVIFHLPELK 1055



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 77/256 (30%), Positives = 118/256 (46%), Gaps = 20/256 (7%)
 Frame = +1

Query: 265  EDVDLNHYRIGKIEGFEVLRKVKTLCLRQN-LIKCIENLEAL----QSLRELDLYDNQIR 429
            E +D +H  +  +EGF  L K+K L L  N L K  + +  L     SL  LD+  N  +
Sbjct: 741  EYLDASHNHVITLEGFRGLMKLKHLDLSWNQLKKSGDEINMLCKHTTSLLTLDIRHNPWQ 800

Query: 430  K--------IENLEALTELEILDISFN----LLRSIEGVDKLTRLKKLFLVNNKINKIEN 573
            K        I  L+ LT L+ + IS       ++ I G  K+T+   L   + K  +   
Sbjct: 801  KPATLRLSVIGRLKTLTHLDGVLISEEEATAAMKFISGT-KITQFSLLRHSSTKEERPRI 859

Query: 574  LSSLRQLQMLELGSNR-IRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 750
            LS     ++L   S     +  + +    + +L L    + ++ NL+ L NL   S  +N
Sbjct: 860  LSIWPSAKILTQTSKLGPHSHMSGNWYLKITALNLDGQHLFEITNLEKLENLKWASFSNN 919

Query: 751  RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIEN--VSHLTEL 924
             LTK+EGL+S VNL EL L  N I  IEG+    KLT L I +N +  +E     ++  L
Sbjct: 920  NLTKMEGLESCVNLEELTLDGNCISKIEGISKLTKLTHLSINNNLLTGLEKHIFDNMLHL 979

Query: 925  QEFWMNDNLLESWSDL 972
                + +N + S S L
Sbjct: 980  HSLSLENNRITSLSGL 995



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 68/244 (27%), Positives = 110/244 (45%), Gaps = 24/244 (9%)
 Frame = +1

Query: 229  VDMETINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCI-------ENLEAL 387
            VD+  ++  R+  +V+L +  +    G   L  VK LCL  N I+ I        +L + 
Sbjct: 1108 VDLIPVDQFRNVCNVNLQNNNLTSFSGLIYLPNVKVLCLNYNHIESIIPRLKPQTHLTSR 1167

Query: 388  QSLRE-----------LDLYDNQIRKIENLEAL-TELEILDISFNLLRSIEGV--DKLTR 525
            Q L +               +      ENL  +   LE+L + +N + ++  +  ++L  
Sbjct: 1168 QLLYQKVPSSGYGQQGTSKMNRDTTSSENLPPIMNSLEVLHLGYNGICNLIQLQLNRLRN 1227

Query: 526  LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
            LK LFL  N+I++IE L +L  LQ L +  NRIRA          +S F           
Sbjct: 1228 LKFLFLQGNEISQIEGLDNLEVLQELVVDHNRIRAFN--------DSAFAKP-------- 1271

Query: 706  LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIE---VIEGLDSNNKLTMLDIA 876
                ++L  L ++ NRL ++  LQ LV L +L+L +N I+    +E LD  + L  L + 
Sbjct: 1272 ----SSLLALHLEENRLRELSKLQPLVKLEKLFLGYNKIQDMAELEKLDGISSLRELTVY 1327

Query: 877  SNRI 888
             N I
Sbjct: 1328 GNPI 1331



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 37/108 (34%), Positives = 60/108 (55%)
 Frame = +1

Query: 634 ENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSH 813
           E  DT + LE  F G  +I  L     LT+LT+++     + +I GL++ + L+EL+++ 
Sbjct: 30  EGSDT-SKLEMFFSGYPRIVGLSLFPNLTSLTIVAQD---IKEISGLETCLQLKELWIAE 85

Query: 814 NGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLE 957
             IE I GL     L  L +  N+I KIEN+  L+ L+  W+N N ++
Sbjct: 86  CCIEKIGGLQECRSLEKLYLYYNKISKIENLEKLSRLEVLWLNHNAIK 133



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 84/363 (23%), Positives = 142/363 (39%), Gaps = 97/363 (26%)
 Frame = +1

Query: 235  METINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIEN--LEALQSLRELD 408
            ME +    + E++ L+   I KIEG   L K+  L +  NL+  +E    + +  L  L 
Sbjct: 924  MEGLESCVNLEELTLDGNCISKIEGISKLTKLTHLSINNNLLTGLEKHIFDNMLHLHSLS 983

Query: 409  LYDNQI-------------------------RKIENLEALTELEILDISFNL-------- 489
            L +N+I                         ++I NL+ L  L ILD+  N+        
Sbjct: 984  LENNRITSLSGLQKAFTLIELYVSNNYIALNQEIYNLKGLCNLVILDMYGNIIVWNQENY 1043

Query: 490  ----------LRSIEGVD----KLTRLKKLF---LVNNKINKIENLSSLRQLQMLELGSN 618
                      L++++G+     +    K LF   L ++ I + +   +  Q+Q L   S+
Sbjct: 1044 RLFVIFHLPELKALDGISIEPPETECAKDLFGGRLTSDMIAERQGHPNFTQMQELNWTSS 1103

Query: 619  RIRAIE--NVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRL------------ 756
             IR ++   VD   N+ ++ L  N +T    L  L N+ VL +  N +            
Sbjct: 1104 SIRTVDLIPVDQFRNVCNVNLQNNNLTSFSGLIYLPNVKVLCLNYNHIESIIPRLKPQTH 1163

Query: 757  ----------------------------TKIEGLQSLVN-LRELYLSHNGIEVIEGLDSN 849
                                        T  E L  ++N L  L+L +NGI  +  L  N
Sbjct: 1164 LTSRQLLYQKVPSSGYGQQGTSKMNRDTTSSENLPPIMNSLEVLHLGYNGICNLIQLQLN 1223

Query: 850  --NKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERT 1023
                L  L +  N I +IE + +L  LQE  ++ N + +++D   A+   SL  ++LE  
Sbjct: 1224 RLRNLKFLFLQGNEISQIEGLDNLEVLQELVVDHNRIRAFNDSAFAK-PSSLLALHLEEN 1282

Query: 1024 PCR 1032
              R
Sbjct: 1283 RLR 1285



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 31/100 (31%), Positives = 53/100 (53%)
 Frame = +1

Query: 595 QMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGL 774
           +++ L    I ++       ++ SL L  N ++KL++L  LT L  L++  N  T ++ +
Sbjct: 675 KLISLDDKTILSLAKTSVYGHIVSLNLHGNSLSKLRDLSKLTGLRKLNISFNEFTCLDDV 734

Query: 775 QSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKK 894
             L NL  L  SHN +  +EG     KL  LD++ N++KK
Sbjct: 735 YHLYNLEYLDASHNHVITLEGFRGLMKLKHLDLSWNQLKK 774



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 45/155 (29%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
 Frame = +1

Query: 502 EGVDKLTRLKKLFLVNNKINKI--ENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFL 675
           E +++   +K+L L N    ++  +  S   +L+M   G  RI  +       NL SL +
Sbjct: 5   ENINQHDIIKELCLCNGLSYEMIGQEGSDTSKLEMFFSGYPRIVGLS---LFPNLTSLTI 61

Query: 676 GKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNK 855
               I ++  L+    L  L +    + KI GLQ   +L +LYL +N I  IE L+  ++
Sbjct: 62  VAQDIKEISGLETCLQLKELWIAECCIEKIGGLQECRSLEKLYLYYNKISKIENLEKLSR 121

Query: 856 LTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
           L +L +  N IK IE +  L  L +  +  NL+ S
Sbjct: 122 LEVLWLNHNAIKYIEGLQTLKNLSDLNLAGNLISS 156


>ref|XP_002700698.1| PREDICTED: Leucine-rich repeat-containing protein 9-like [Bos
           taurus].
          Length = 1538

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 64/201 (31%), Positives = 107/201 (53%), Gaps = 4/201 (1%)
 Frame = +1

Query: 355 LIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKK 534
           +I+C EN+     ++EL L +    ++   E  ++   L++ F+    I G+     L  
Sbjct: 1   MIEC-ENINQHDIIKELCLCNGLSYEMIGQEG-SDTSKLEMFFSGYPRIVGLSLFPNLTS 58

Query: 535 LFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDA 714
           L +V   I +I  L +  QL+ L +    I  I  +    +LE L+L  NKI+K++NL+ 
Sbjct: 59  LTIVAQDIKEISGLETCLQLKELWIAECCIEKIGGLQECRSLEKLYLYYNKISKIENLEK 118

Query: 715 LTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVI-EGLDSNNKLTMLDIASNRI- 888
           L+ L VL +  N +  IEGLQ+L NL +L L+ N I  I   LD N +L  L+++ N+I 
Sbjct: 119 LSRLEVLWLNHNAIKYIEGLQTLKNLSDLNLAGNLISSIGRCLDPNEQLERLNLSGNQIC 178

Query: 889 --KKIENVSHLTELQEFWMND 945
             K + N++ L  L++  +ND
Sbjct: 179 SFKDLTNLTRLRHLKDLCLND 199



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 59/208 (28%), Positives = 100/208 (48%), Gaps = 17/208 (8%)
 Frame = +1

Query: 367 IENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLV 546
           I  L    +L  L +    I++I  LE   +L+ L I+   +  I G+ +   L+KL+L 
Sbjct: 47  IVGLSLFPNLTSLTIVAQDIKEISGLETCLQLKELWIAECCIEKIGGLQECRSLEKLYLY 106

Query: 547 NNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKL-QNLDALTN 723
            NKI+KIENL  L +L++L L  N I+ IE + TL NL  L L  N I+ + + LD    
Sbjct: 107 YNKISKIENLEKLSRLEVLWLNHNAIKYIEGLQTLKNLSDLNLAGNLISSIGRCLDPNEQ 166

Query: 724 LTVLSMQSNRLTKIEGLQSLVNLREL----------------YLSHNGIEVIEGLDSNNK 855
           L  L++  N++   + L +L  LR L                 L +    V+  L    +
Sbjct: 167 LERLNLSGNQICSFKDLTNLTRLRHLKDLCLNDPQYKTNPVCLLCNYSTHVLYHLPCLQR 226

Query: 856 LTMLDIASNRIKKIENVSHLTELQEFWM 939
           L   D++  +IK++ + + + ++  + M
Sbjct: 227 LDTFDVSPKQIKELADTTAMKKIMYYNM 254



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 48/127 (37%), Positives = 72/127 (56%), Gaps = 1/127 (0%)
 Frame = +1

Query: 292 IGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEIL 471
           I +I G E   ++K L + +  I+ I  L+  +SL +L LY N+I KIENLE L+ LE+L
Sbjct: 66  IKEISGLETCLQLKELWIAECCIEKIGGLQECRSLEKLYLYYNKISKIENLEKLSRLEVL 125

Query: 472 DISFNLLRSIEGVDKLTRLKKLFLVNNKINKIEN-LSSLRQLQMLELGSNRIRAIENVDT 648
            ++ N ++ IEG+  L  L  L L  N I+ I   L    QL+ L L  N+I + +++  
Sbjct: 126 WLNHNAIKYIEGLQTLKNLSDLNLAGNLISSIGRCLDPNEQLERLNLSGNQICSFKDLTN 185

Query: 649 LTNLESL 669
           LT L  L
Sbjct: 186 LTRLRHL 192



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 55/168 (32%), Positives = 84/168 (50%), Gaps = 11/168 (6%)
 Frame = +1

Query: 457  ELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIE 636
            ++  L++    L  I  ++KL  LK     NN + K+E L S   L+ L L  N I  IE
Sbjct: 888  KITALNLDGQHLFEITNLEKLENLKWASFSNNNLTKMEGLESCVNLEELTLDGNCISKIE 947

Query: 637  NVDTLTNLESLFLGKNKITKLQN--LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLS 810
             +  LT L  L +  N +T L+    D + +L  LS+++NR+T + GLQ    L ELY+S
Sbjct: 948  GISKLTKLTHLSINNNLLTGLEKHIFDNMLHLHSLSLENNRITSLSGLQKAFTLIELYVS 1007

Query: 811  HNGI---EVIEGLDSNNKLTMLDIASNRI------KKIENVSHLTELQ 927
            +N I   + I  L     L +LD+  N I       ++  + HL EL+
Sbjct: 1008 NNYIALNQEIYNLKGLCNLVILDMYGNIIVWNQENYRLFVIFHLPELK 1055



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 77/256 (30%), Positives = 118/256 (46%), Gaps = 20/256 (7%)
 Frame = +1

Query: 265  EDVDLNHYRIGKIEGFEVLRKVKTLCLRQN-LIKCIENLEAL----QSLRELDLYDNQIR 429
            E +D +H  +  +EGF  L K+K L L  N L K  + +  L     SL  LD+  N  +
Sbjct: 741  EYLDASHNHVITLEGFRGLMKLKHLDLSWNQLKKSGDEINMLCKHTTSLLTLDIRHNPWQ 800

Query: 430  K--------IENLEALTELEILDISFN----LLRSIEGVDKLTRLKKLFLVNNKINKIEN 573
            K        I  L+ LT L+ + IS       ++ I G  K+T+   L   + K  +   
Sbjct: 801  KPATLRLSVIGRLKTLTHLDGVLISEEEATAAMKFISGT-KITQFSLLRHSSTKEERPRI 859

Query: 574  LSSLRQLQMLELGSNR-IRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 750
            LS     ++L   S     +  + +    + +L L    + ++ NL+ L NL   S  +N
Sbjct: 860  LSIWPSAKILTQTSKLGPHSHMSGNWYLKITALNLDGQHLFEITNLEKLENLKWASFSNN 919

Query: 751  RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIEN--VSHLTEL 924
             LTK+EGL+S VNL EL L  N I  IEG+    KLT L I +N +  +E     ++  L
Sbjct: 920  NLTKMEGLESCVNLEELTLDGNCISKIEGISKLTKLTHLSINNNLLTGLEKHIFDNMLHL 979

Query: 925  QEFWMNDNLLESWSDL 972
                + +N + S S L
Sbjct: 980  HSLSLENNRITSLSGL 995



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 68/244 (27%), Positives = 110/244 (45%), Gaps = 24/244 (9%)
 Frame = +1

Query: 229  VDMETINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCI-------ENLEAL 387
            VD+  ++  R+  +V+L +  +    G   L  VK LCL  N I+ I        +L + 
Sbjct: 1108 VDLIPVDQFRNVCNVNLQNNNLTSFSGLIYLPNVKVLCLNYNHIESIIPRLKPQTHLTSR 1167

Query: 388  QSLRE-----------LDLYDNQIRKIENLEAL-TELEILDISFNLLRSIEGV--DKLTR 525
            Q L +               +      ENL  +   LE+L + +N + ++  +  ++L  
Sbjct: 1168 QLLYQKVPSSGYGQQGTSKMNRDTTSSENLPPIMNSLEVLHLGYNGICNLIQLQLNRLRN 1227

Query: 526  LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
            LK LFL  N+I++IE L +L  LQ L +  NRIRA          +S F           
Sbjct: 1228 LKFLFLQGNEISQIEGLDNLEVLQELVVDHNRIRAFN--------DSAFAKP-------- 1271

Query: 706  LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIE---VIEGLDSNNKLTMLDIA 876
                ++L  L ++ NRL ++  LQ LV L +L+L +N I+    +E LD  + L  L + 
Sbjct: 1272 ----SSLLALHLEENRLRELSKLQPLVKLEKLFLGYNKIQDMAELEKLDGISSLRELTVY 1327

Query: 877  SNRI 888
             N I
Sbjct: 1328 GNPI 1331



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 37/108 (34%), Positives = 60/108 (55%)
 Frame = +1

Query: 634 ENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSH 813
           E  DT + LE  F G  +I  L     LT+LT+++     + +I GL++ + L+EL+++ 
Sbjct: 30  EGSDT-SKLEMFFSGYPRIVGLSLFPNLTSLTIVAQD---IKEISGLETCLQLKELWIAE 85

Query: 814 NGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLE 957
             IE I GL     L  L +  N+I KIEN+  L+ L+  W+N N ++
Sbjct: 86  CCIEKIGGLQECRSLEKLYLYYNKISKIENLEKLSRLEVLWLNHNAIK 133



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 84/363 (23%), Positives = 142/363 (39%), Gaps = 97/363 (26%)
 Frame = +1

Query: 235  METINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIEN--LEALQSLRELD 408
            ME +    + E++ L+   I KIEG   L K+  L +  NL+  +E    + +  L  L 
Sbjct: 924  MEGLESCVNLEELTLDGNCISKIEGISKLTKLTHLSINNNLLTGLEKHIFDNMLHLHSLS 983

Query: 409  LYDNQI-------------------------RKIENLEALTELEILDISFNL-------- 489
            L +N+I                         ++I NL+ L  L ILD+  N+        
Sbjct: 984  LENNRITSLSGLQKAFTLIELYVSNNYIALNQEIYNLKGLCNLVILDMYGNIIVWNQENY 1043

Query: 490  ----------LRSIEGVD----KLTRLKKLF---LVNNKINKIENLSSLRQLQMLELGSN 618
                      L++++G+     +    K LF   L ++ I + +   +  Q+Q L   S+
Sbjct: 1044 RLFVIFHLPELKALDGISIEPPETECAKDLFGGRLTSDMIAERQGHPNFTQMQELNWTSS 1103

Query: 619  RIRAIE--NVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRL------------ 756
             IR ++   VD   N+ ++ L  N +T    L  L N+ VL +  N +            
Sbjct: 1104 SIRTVDLIPVDQFRNVCNVNLQNNNLTSFSGLIYLPNVKVLCLNYNHIESIIPRLKPQTH 1163

Query: 757  ----------------------------TKIEGLQSLVN-LRELYLSHNGIEVIEGLDSN 849
                                        T  E L  ++N L  L+L +NGI  +  L  N
Sbjct: 1164 LTSRQLLYQKVPSSGYGQQGTSKMNRDTTSSENLPPIMNSLEVLHLGYNGICNLIQLQLN 1223

Query: 850  --NKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERT 1023
                L  L +  N I +IE + +L  LQE  ++ N + +++D   A+   SL  ++LE  
Sbjct: 1224 RLRNLKFLFLQGNEISQIEGLDNLEVLQELVVDHNRIRAFNDSAFAK-PSSLLALHLEEN 1282

Query: 1024 PCR 1032
              R
Sbjct: 1283 RLR 1285



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 31/100 (31%), Positives = 53/100 (53%)
 Frame = +1

Query: 595 QMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGL 774
           +++ L    I ++       ++ SL L  N ++KL++L  LT L  L++  N  T ++ +
Sbjct: 675 KLISLDDKTILSLAKTSVYGHIVSLNLHGNSLSKLRDLSKLTGLRKLNISFNEFTCLDDV 734

Query: 775 QSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKK 894
             L NL  L  SHN +  +EG     KL  LD++ N++KK
Sbjct: 735 YHLYNLEYLDASHNHVITLEGFRGLMKLKHLDLSWNQLKK 774



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 45/155 (29%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
 Frame = +1

Query: 502 EGVDKLTRLKKLFLVNNKINKI--ENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFL 675
           E +++   +K+L L N    ++  +  S   +L+M   G  RI  +       NL SL +
Sbjct: 5   ENINQHDIIKELCLCNGLSYEMIGQEGSDTSKLEMFFSGYPRIVGLS---LFPNLTSLTI 61

Query: 676 GKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNK 855
               I ++  L+    L  L +    + KI GLQ   +L +LYL +N I  IE L+  ++
Sbjct: 62  VAQDIKEISGLETCLQLKELWIAECCIEKIGGLQECRSLEKLYLYYNKISKIENLEKLSR 121

Query: 856 LTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
           L +L +  N IK IE +  L  L +  +  NL+ S
Sbjct: 122 LEVLWLNHNAIKYIEGLQTLKNLSDLNLAGNLISS 156


>ref|NP_001179616.1| leucine-rich repeat and guanylate kinase domain-containing protein
            [Bos taurus].
          Length = 829

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 58/214 (27%), Positives = 107/214 (50%)
 Frame = +1

Query: 391  SLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIE 570
            +L +LDL D  I     L     L+ LD+S N +  +  V  +  L +L    N +    
Sbjct: 139  TLSDLDLTDVSI-----LCGYVHLQKLDLSVNKIEDLSCVSCMPYLLELNASQNHLKTFF 193

Query: 571  NLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 750
            N    ++L+ ++   N+I  + ++    +L  L L  N+IT++  L+  ++LT LS+ +N
Sbjct: 194  NFKPPKKLKKVDFSYNQISEMCSLSAYESLTKLILDSNEITEISGLELCSSLTYLSLANN 253

Query: 751  RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQE 930
            ++T I GL  ++ ++ L LS+N IE + GLD    L +LD++ N+I  ++ +     L+ 
Sbjct: 254  KITTINGL-GMLPIKILCLSNNQIEKMTGLDDLRVLQILDLSQNQISSLQGLEGHDFLEV 312

Query: 931  FWMNDNLLESWSDLX*AQGAQSLETVYLERTPCR 1032
              + DN +    ++   +    L  + L R P R
Sbjct: 313  INLEDNKVAELGEIEYIENLPLLRVLNLLRNPVR 346



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 39/133 (29%), Positives = 68/133 (51%), Gaps = 6/133 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           + L + +I  I G  +L  +K LCL  N I+ +  L+ L+ L+ LDL  NQI  ++ LE 
Sbjct: 248 LSLANNKITTINGLGML-PIKILCLSNNQIEKMTGLDDLRVLQILDLSQNQISSLQGLEG 306

Query: 451 LTELEILDISFNL---LRSIEGVDKLTRLKKLFLVNNKINKIENLSS---LRQLQMLELG 612
              LE++++  N    L  IE ++ L  L+ L L+ N + +  +  S      L++ EL 
Sbjct: 307 HDFLEVINLEDNKVAELGEIEYIENLPLLRVLNLLRNPVREKPDYWSFVIFMLLRLTELD 366

Query: 613 SNRIRAIENVDTL 651
             +I+  E +  +
Sbjct: 367 QKKIKVDEKISAV 379


  Database: RefSeq49_BP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 17,681,374
  Number of sequences in database:  33,088
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33088
Number of Hits to DB: 31,261,516
Number of extensions: 756014
Number of successful extensions: 3850
Number of sequences better than 1.0e-05: 100
Number of HSP's gapped: 3600
Number of HSP's successfully gapped: 181
Length of query: 346
Length of database: 17,681,374
Length adjustment: 103
Effective length of query: 243
Effective length of database: 14,273,310
Effective search space: 3468414330
Effective search space used: 3468414330
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 34 (17.7 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007857
         (1040 letters)

Database: RefSeq49_CP.fasta 
           33,336 sequences; 18,874,504 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|XP_534627.2| PREDICTED: similar to protein phosphatase 1, re...   473   e-133
Alignment   gi|XP_544751.2| PREDICTED: similar to leucine rich repeat conta...   101   1e-21
Alignment   gi|XP_547839.2| PREDICTED: similar to T05H4.3 [Canis familiaris].     87   2e-17
Alignment   gi|XP_532416.2| PREDICTED: similar to leucine rich protein, B7 ...    85   1e-16
Alignment   gi|XP_536764.2| PREDICTED: similar to leucine rich repeat conta...    83   4e-16
Alignment   gi|XP_850685.1| PREDICTED: similar to leucine-rich repeats and ...    83   5e-16
Alignment   gi|XP_536663.2| PREDICTED: similar to leucine rich repeat conta...    82   6e-16
Alignment   gi|XP_541218.2| PREDICTED: similar to Platelet glycoprotein V p...    79   9e-15
Alignment   gi|XP_531654.2| PREDICTED: similar to leucine-rich repeats and ...    77   3e-14
Alignment   gi|XP_867175.1| PREDICTED: similar to T-cell activation leucine...    77   4e-14

>ref|XP_534627.2| PREDICTED: similar to protein phosphatase 1, regulatory subunit 7,
           partial [Canis familiaris].
          Length = 302

 Score =  473 bits (1216), Expect = e-133
 Identities = 250/302 (82%), Positives = 264/302 (87%)
 Frame = +1

Query: 31  MAAERGTGQQQSQEMMEVDRRVXXXXXXXXXXXXXXXXIVADLSEHSLKDXXXXXXXXXX 210
           MAAERG GQQQSQEMMEVDRRV                IVADLSE SLKD          
Sbjct: 1   MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKQSSGIVADLSEQSLKDGEEQGEEDPE 60

Query: 211 XXXXXXVDMETINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQ 390
                 VDMETI+LDRDAED+DLNHYRIGKIEGFEVL+KVKTLCLRQNLIKCIENL  LQ
Sbjct: 61  EGQELPVDMETISLDRDAEDIDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLGELQ 120

Query: 391 SLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIE 570
           SLRELDLYDNQI+KIENLEALT LEILDISFNLLR+IEGVDKLTRL+KLFLVNNKI+KIE
Sbjct: 121 SLRELDLYDNQIKKIENLEALTHLEILDISFNLLRNIEGVDKLTRLRKLFLVNNKISKIE 180

Query: 571 NLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 750
           N+S+L QLQMLELGSNRIRAIEN+DTLT+LESLFLGKNKITKLQNLDALTNLTVLSMQSN
Sbjct: 181 NISNLHQLQMLELGSNRIRAIENIDTLTSLESLFLGKNKITKLQNLDALTNLTVLSMQSN 240

Query: 751 RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQE 930
           RLTK+EGLQSLVNLRELYLSHNGIEVIEGL++NNKLTMLDIASNRIKKIENVSHLTELQE
Sbjct: 241 RLTKMEGLQSLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENVSHLTELQE 300

Query: 931 FW 936
           FW
Sbjct: 301 FW 302



 Score =  107 bits (267), Expect = 2e-23
 Identities = 68/193 (35%), Positives = 108/193 (55%)
 Frame = +1

Query: 394 LRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIEN 573
           L E  L D + +  E+ E   EL +   + +L R  E +D         L + +I KIE 
Sbjct: 43  LSEQSLKDGEEQGEEDPEEGQELPVDMETISLDRDAEDID---------LNHYRIGKIEG 93

Query: 574 LSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNR 753
              L++++ L L  N I+ IEN+  L +L  L L  N+I K++NL+ALT+L +L +  N 
Sbjct: 94  FEVLKKVKTLCLRQNLIKCIENLGELQSLRELDLYDNQIKKIENLEALTHLEILDISFNL 153

Query: 754 LTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEF 933
           L  IEG+  L  LR+L+L +N I  IE + + ++L ML++ SNRI+ IEN+  LT L+  
Sbjct: 154 LRNIEGVDKLTRLRKLFLVNNKISKIENISNLHQLQMLELGSNRIRAIENIDTLTSLESL 213

Query: 934 WMNDNLLESWSDL 972
           ++  N +    +L
Sbjct: 214 FLGKNKITKLQNL 226


>ref|XP_544751.2| PREDICTED: similar to leucine rich repeat containing 49 [Canis
           familiaris].
          Length = 686

 Score =  101 bits (252), Expect = 1e-21
 Identities = 68/212 (32%), Positives = 110/212 (51%), Gaps = 3/212 (1%)
 Frame = +1

Query: 346 RQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTR 525
           RQ L  C   ++  + LR L+   N I +I+N+  L  L  LD+  N +  I G+  L  
Sbjct: 99  RQKLTVC-PIIDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLRS 157

Query: 526 LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
           L+ L L  N+I KI NL +L+ L +L+L  N+I  IENV+ L +L  L L +N ++ + N
Sbjct: 158 LRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDN 217

Query: 706 LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEG---LDSNNKLTMLDIA 876
           L+ L +LT L+++ N++T +  + +L  L+ L+LS N I   E    L  ++ L+ +   
Sbjct: 218 LNGLDSLTELNLRHNQITFVRDVDNLPCLQRLFLSFNNISTFESVCCLADSSSLSDITFD 277

Query: 877 SNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            N I            QE W    +L++   L
Sbjct: 278 GNPI-----------AQESWYKHTILQNMMQL 298



 Score = 99.8 bits (247), Expect = 4e-21
 Identities = 56/173 (32%), Positives = 100/173 (57%)
 Frame = +1

Query: 508  VDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNK 687
            +D    L+ L   +N I +I+N+S+L++L  L+L  N+I  I  + TL +L  L LGKN+
Sbjct: 108  IDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLRSLRVLLLGKNR 167

Query: 688  ITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTML 867
            I K+ NL+ L +L VL +  N++TKIE +  L +LR L L+ N +  ++ L+  + LT L
Sbjct: 168  IKKISNLENLKSLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTEL 227

Query: 868  DIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERTP 1026
            ++  N+I  + +V +L  LQ  +++ N + ++  +     + SL  +  +  P
Sbjct: 228  NLRHNQITFVRDVDNLPCLQRLFLSFNNISTFESVCCLADSSSLSDITFDGNP 280



 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 62/185 (33%), Positives = 102/185 (55%), Gaps = 8/185 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           ++  H  I +I+    L+++  L L  N I+ I  L  L+SLR L L  N+I+KI NLE 
Sbjct: 117 LNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLRSLRVLLLGKNRIKKISNLEN 176

Query: 451 LTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRA 630
           L  L++LD+  N +  IE V+ L  L+ L L  N ++ ++NL+ L  L  L L  N+I  
Sbjct: 177 LKSLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQITF 236

Query: 631 IENVDTLTNLESLFLGKNKITKLQNLDAL---TNLTVLSMQSNRLT-----KIEGLQSLV 786
           + +VD L  L+ LFL  N I+  +++  L   ++L+ ++   N +      K   LQ+++
Sbjct: 237 VRDVDNLPCLQRLFLSFNNISTFESVCCLADSSSLSDITFDGNPIAQESWYKHTILQNMM 296

Query: 787 NLREL 801
            LR+L
Sbjct: 297 QLRQL 301



 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 43/124 (34%), Positives = 67/124 (54%)
 Frame = +1

Query: 601 LELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQS 780
           L L   ++     +D   +L  L    N IT++QN+  L  L  L +  N++ +I GL +
Sbjct: 95  LTLERQKLTVCPIIDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLST 154

Query: 781 LVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
           L +LR L L  N I+ I  L++   L +LD+  N+I KIENV+HL +L+   +  NLL  
Sbjct: 155 LRSLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSH 214

Query: 961 WSDL 972
             +L
Sbjct: 215 VDNL 218



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 47/154 (30%), Positives = 76/154 (49%)
 Frame = +1

Query: 487 LLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLES 666
           L RS E  +K+    +L L   K+     +     L++L    N I  I+N+  L  L  
Sbjct: 81  LQRSSE--EKILYSDRLTLERQKLTVCPIIDGEEHLRLLNFQHNFITRIQNISNLQRLIF 138

Query: 667 LFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDS 846
           L L  N+I ++  L  L +L VL +  NR+ KI  L++L +L  L L  N I  IE ++ 
Sbjct: 139 LDLYDNQIEEISGLSTLRSLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENVNH 198

Query: 847 NNKLTMLDIASNRIKKIENVSHLTELQEFWMNDN 948
              L +L++A N +  ++N++ L  L E  +  N
Sbjct: 199 LCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHN 232


>ref|XP_547839.2| PREDICTED: similar to T05H4.3 [Canis familiaris].
          Length = 1687

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 65/201 (32%), Positives = 107/201 (53%), Gaps = 4/201 (1%)
 Frame = +1

Query: 355 LIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKK 534
           +I+C ENL   + ++EL L +    ++   E  ++   L++ F+    I G+     L  
Sbjct: 103 MIEC-ENLNQEEIIKELCLCNGLSYEMVGREG-SDTSKLEMFFSGYPRIVGLSLFPNLTS 160

Query: 535 LFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDA 714
           L +V   I +I  L +  +L+ L +    I  I  +    NLE L+L  NKI+K++NL+ 
Sbjct: 161 LTIVAQDIKEISGLETCSRLKELWIAECCIEKIGGLQECRNLEKLYLYYNKISKIENLEK 220

Query: 715 LTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVI-EGLDSNNKLTMLDIASNRI- 888
           L  L VL +  N +  IEGLQ+L NL +L L+ N I  I   LD N +L  L+++ N+I 
Sbjct: 221 LLRLEVLWLNHNTIKNIEGLQTLKNLNDLNLAGNLISSIGRCLDPNEQLERLNLSGNQIC 280

Query: 889 --KKIENVSHLTELQEFWMND 945
             K + N++ L  L++  +ND
Sbjct: 281 SFKDLTNLTRLHRLKDLCLND 301



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 17/208 (8%)
 Frame = +1

Query: 367 IENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLV 546
           I  L    +L  L +    I++I  LE  + L+ L I+   +  I G+ +   L+KL+L 
Sbjct: 149 IVGLSLFPNLTSLTIVAQDIKEISGLETCSRLKELWIAECCIEKIGGLQECRNLEKLYLY 208

Query: 547 NNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKL-QNLDALTN 723
            NKI+KIENL  L +L++L L  N I+ IE + TL NL  L L  N I+ + + LD    
Sbjct: 209 YNKISKIENLEKLLRLEVLWLNHNTIKNIEGLQTLKNLNDLNLAGNLISSIGRCLDPNEQ 268

Query: 724 LTVLSMQSNRLTKIEGLQSLVNLREL----------------YLSHNGIEVIEGLDSNNK 855
           L  L++  N++   + L +L  L  L                 L +    V+  L S  +
Sbjct: 269 LERLNLSGNQICSFKDLTNLTRLHRLKDLCLNDPQYKTNPVCLLCNYSTHVLYHLPSLQR 328

Query: 856 LTMLDIASNRIKKIENVSHLTELQEFWM 939
           L   D+++ +IK++ + + + ++  + M
Sbjct: 329 LDTFDVSAKQIKELADTTAMKKIMYYNM 356



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 47/127 (37%), Positives = 72/127 (56%), Gaps = 1/127 (0%)
 Frame = +1

Query: 292 IGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEIL 471
           I +I G E   ++K L + +  I+ I  L+  ++L +L LY N+I KIENLE L  LE+L
Sbjct: 168 IKEISGLETCSRLKELWIAECCIEKIGGLQECRNLEKLYLYYNKISKIENLEKLLRLEVL 227

Query: 472 DISFNLLRSIEGVDKLTRLKKLFLVNNKINKIEN-LSSLRQLQMLELGSNRIRAIENVDT 648
            ++ N +++IEG+  L  L  L L  N I+ I   L    QL+ L L  N+I + +++  
Sbjct: 228 WLNHNTIKNIEGLQTLKNLNDLNLAGNLISSIGRCLDPNEQLERLNLSGNQICSFKDLTN 287

Query: 649 LTNLESL 669
           LT L  L
Sbjct: 288 LTRLHRL 294



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 55/168 (32%), Positives = 85/168 (50%), Gaps = 11/168 (6%)
 Frame = +1

Query: 457  ELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIE 636
            ++  L++    L  I  ++KL  LK     NN + K+E L S   L+ L L  N I  IE
Sbjct: 989  KITALNLDGQHLFEITNLEKLENLKWASFSNNNLTKMEGLESCVNLEELTLDGNCISKIE 1048

Query: 637  NVDTLTNLESLFLGKNKITKLQN--LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLS 810
             +  LT L  L +  N +T L+    D + +L  LS+++NR+T + GLQ  + L ELY+S
Sbjct: 1049 GISRLTKLTRLSINNNLLTGLEKHTFDNMLHLHSLSLENNRITSLSGLQKALTLIELYIS 1108

Query: 811  HNGI---EVIEGLDSNNKLTMLDIASNRI------KKIENVSHLTELQ 927
            +N I   + I  L     L +LD+  N I       ++  + HL EL+
Sbjct: 1109 NNYIALNQEIYNLKGLCNLVILDMHGNIIVWNQENYRLFVIFHLPELK 1156



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 83/270 (30%), Positives = 126/270 (46%), Gaps = 20/270 (7%)
 Frame = +1

Query: 265  EDVDLNHYRIGKIEGFEVLRKVKTLCLRQN-LIKCIENLEAL----QSLRELDLYDNQIR 429
            E +D +H  +  +EGF  L K+K L L  N L K  + +  L     SL  LD+  N  +
Sbjct: 842  EYLDASHNHVITLEGFRGLMKLKHLDLSWNQLKKSGDEINMLCKHTTSLLTLDIRHNPWQ 901

Query: 430  K--------IENLEALTELEILDISFN----LLRSIEGVDKLTRLKKLFLVNNKINKIEN 573
            K        I  L+ LT L+ L IS       ++ I G  K+T+L  L   + K  +   
Sbjct: 902  KPATLRLSVIGRLKTLTHLDGLLISEEEATAAMKFITGT-KITQLSLLQHSSIKEERPRI 960

Query: 574  LSSLRQLQMLELGSNRIRAIE-NVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 750
            LS     ++L   S     +  + +    + +L L    + ++ NL+ L NL   S  +N
Sbjct: 961  LSIWPSAKILTQISKLGPHLHLSGNWYLKITALNLDGQHLFEITNLEKLENLKWASFSNN 1020

Query: 751  RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIE--NVSHLTEL 924
             LTK+EGL+S VNL EL L  N I  IEG+    KLT L I +N +  +E     ++  L
Sbjct: 1021 NLTKMEGLESCVNLEELTLDGNCISKIEGISRLTKLTRLSINNNLLTGLEKHTFDNMLHL 1080

Query: 925  QEFWMNDNLLESWSDLX*AQGAQSLETVYL 1014
                + +N + S S L   Q A +L  +Y+
Sbjct: 1081 HSLSLENNRITSLSGL---QKALTLIELYI 1107



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 73/262 (27%), Positives = 114/262 (43%), Gaps = 29/262 (11%)
 Frame = +1

Query: 229  VDMETINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCI----------ENL 378
            VD+  ++  R+  +V+L +  +    G   L  VK LCL  N I+ I           N 
Sbjct: 1209 VDLIPVDQFRNVCNVNLQNNNLTSFSGLIYLPNVKVLCLNYNHIESIIPRVKPQTHLTNR 1268

Query: 379  EALQSLRELDLYDNQ--------IRKIENLEALT-ELEILDISFNLLRSI--EGVDKLTR 525
            + L        Y  Q        I   ENL  +   LE+L + +N + ++    +++L  
Sbjct: 1269 QLLYQKVPSSGYGQQGTSKINRDIMSSENLPPIMHSLEVLHLGYNGICNLIQLQLNRLRN 1328

Query: 526  LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
            LK LFL  N+I++IE L +L  LQ L +  NRIRA          +S F           
Sbjct: 1329 LKFLFLQGNEISQIEGLDNLVVLQELVVDHNRIRAFN--------DSAFAKP-------- 1372

Query: 706  LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNN-------KLTM 864
                ++L  L ++ NRL ++  LQ LV L +L+L +N I++       +        L M
Sbjct: 1373 ----SSLLALHLEENRLRELSRLQPLVKLEKLFLGYNKIQICRKTLHRHVLVFRLPNLQM 1428

Query: 865  LD-IASNRIKKIENVSHLTELQ 927
            LD I  N   + +   H +ELQ
Sbjct: 1429 LDGIPVNSDDRAKAEFHFSELQ 1450



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 52/200 (26%), Positives = 100/200 (50%), Gaps = 6/200 (3%)
 Frame = +1

Query: 376  LEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNK 555
            ++  +++  ++L +N +     L  L  +++L +++N + SI     + R+K    + N+
Sbjct: 1214 VDQFRNVCNVNLQNNNLTSFSGLIYLPNVKVLCLNYNHIESI-----IPRVKPQTHLTNR 1268

Query: 556  INKIENLSSLRQLQMLELGSNR-IRAIENVDTLTN-LESLFLGKNKITKL--QNLDALTN 723
                + + S    Q      NR I + EN+  + + LE L LG N I  L    L+ L N
Sbjct: 1269 QLLYQKVPSSGYGQQGTSKINRDIMSSENLPPIMHSLEVLHLGYNGICNLIQLQLNRLRN 1328

Query: 724  LTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVI--EGLDSNNKLTMLDIASNRIKKI 897
            L  L +Q N +++IEGL +LV L+EL + HN I           + L  L +  NR++++
Sbjct: 1329 LKFLFLQGNEISQIEGLDNLVVLQELVVDHNRIRAFNDSAFAKPSSLLALHLEENRLREL 1388

Query: 898  ENVSHLTELQEFWMNDNLLE 957
              +  L +L++ ++  N ++
Sbjct: 1389 SRLQPLVKLEKLFLGYNKIQ 1408



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 46/156 (29%), Positives = 81/156 (51%), Gaps = 3/156 (1%)
 Frame = +1

Query: 550  NKINKIENLSS---LRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALT 720
            +K+ + ENL+    +++L +    S  +   E  DT + LE  F G  +I  L     LT
Sbjct: 101  SKMIECENLNQEEIIKELCLCNGLSYEMVGREGSDT-SKLEMFFSGYPRIVGLSLFPNLT 159

Query: 721  NLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIE 900
            +LT+++     + +I GL++   L+EL+++   IE I GL     L  L +  N+I KIE
Sbjct: 160  SLTIVAQD---IKEISGLETCSRLKELWIAECCIEKIGGLQECRNLEKLYLYYNKISKIE 216

Query: 901  NVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETV 1008
            N+  L  L+  W+N N +++       +G Q+L+ +
Sbjct: 217  NLEKLLRLEVLWLNHNTIKN------IEGLQTLKNL 246



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 53/189 (28%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
 Frame = +1

Query: 400 ELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENL- 576
           EL +Y +Q   + +L  L+   I  +  + +   E +++   +K+L L N    ++    
Sbjct: 74  ELGVYTHQAPDL-SLSNLSTPIITKLPASKMIECENLNQEEIIKELCLCNGLSYEMVGRE 132

Query: 577 -SSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNR 753
            S   +L+M   G  RI  +       NL SL +    I ++  L+  + L  L +    
Sbjct: 133 GSDTSKLEMFFSGYPRIVGLS---LFPNLTSLTIVAQDIKEISGLETCSRLKELWIAECC 189

Query: 754 LTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEF 933
           + KI GLQ   NL +LYL +N I  IE L+   +L +L +  N IK IE +  L  L + 
Sbjct: 190 IEKIGGLQECRNLEKLYLYYNKISKIENLEKLLRLEVLWLNHNTIKNIEGLQTLKNLNDL 249

Query: 934 WMNDNLLES 960
            +  NL+ S
Sbjct: 250 NLAGNLISS 258



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 83/363 (22%), Positives = 143/363 (39%), Gaps = 97/363 (26%)
 Frame = +1

Query: 235  METINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIE--NLEALQSLRELD 408
            ME +    + E++ L+   I KIEG   L K+  L +  NL+  +E    + +  L  L 
Sbjct: 1025 MEGLESCVNLEELTLDGNCISKIEGISRLTKLTRLSINNNLLTGLEKHTFDNMLHLHSLS 1084

Query: 409  LYDNQI-------------------------RKIENLEALTELEILDISFNL-------- 489
            L +N+I                         ++I NL+ L  L ILD+  N+        
Sbjct: 1085 LENNRITSLSGLQKALTLIELYISNNYIALNQEIYNLKGLCNLVILDMHGNIIVWNQENY 1144

Query: 490  ----------LRSIEGVD----KLTRLKKLF---LVNNKINKIENLSSLRQLQMLELGSN 618
                      L++++G+     +    K LF   L ++ I + +  S+  ++Q L   S+
Sbjct: 1145 RLFVIFHLPELKALDGISIEAPETECAKDLFGGRLTSDMIAERQGHSNFTEMQELNWTSS 1204

Query: 619  RIRAIE--NVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKI--------- 765
             IR ++   VD   N+ ++ L  N +T    L  L N+ VL +  N +  I         
Sbjct: 1205 SIRTVDLIPVDQFRNVCNVNLQNNNLTSFSGLIYLPNVKVLCLNYNHIESIIPRVKPQTH 1264

Query: 766  -------------------------------EGLQSLV-NLRELYLSHNGIEVIEGLDSN 849
                                           E L  ++ +L  L+L +NGI  +  L  N
Sbjct: 1265 LTNRQLLYQKVPSSGYGQQGTSKINRDIMSSENLPPIMHSLEVLHLGYNGICNLIQLQLN 1324

Query: 850  --NKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERT 1023
                L  L +  N I +IE + +L  LQE  ++ N + +++D   A+   SL  ++LE  
Sbjct: 1325 RLRNLKFLFLQGNEISQIEGLDNLVVLQELVVDHNRIRAFNDSAFAK-PSSLLALHLEEN 1383

Query: 1024 PCR 1032
              R
Sbjct: 1384 RLR 1386



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 31/100 (31%), Positives = 53/100 (53%)
 Frame = +1

Query: 595  QMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGL 774
            ++  L    I ++      +++ SL L  N ++KL++L  LT L  L++  N  T ++ +
Sbjct: 776  KLTSLDDKTILSLAKTSIYSHIVSLNLHGNSLSKLKDLSKLTGLRKLNISFNEFTCLDDV 835

Query: 775  QSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKK 894
              L NL  L  SHN +  +EG     KL  LD++ N++KK
Sbjct: 836  YHLYNLEYLDASHNHVITLEGFRGLMKLKHLDLSWNQLKK 875


>ref|XP_532416.2| PREDICTED: similar to leucine rich protein, B7 gene (predicted)
           [Canis familiaris].
          Length = 825

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 52/177 (29%), Positives = 99/177 (55%)
 Frame = +1

Query: 394 LRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIEN 573
           L++LDL  N+I  +  +  +  L  L+ S N L +         LKK+    N+I+++ +
Sbjct: 151 LQKLDLSVNKIEDLSCVSYMPYLLELNASHNKLTTFFNFKPPKNLKKVDFSYNQISEMRD 210

Query: 574 LSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNR 753
           LS+ + L  L L +N I  I  ++  + L  L L KN+IT +  L  L  + +L + +N+
Sbjct: 211 LSAYQALTKLILDNNEIEEISGLELCSGLTHLSLAKNRITTINGLGILP-IKILCLSNNQ 269

Query: 754 LTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTEL 924
           + KI GL+ L  L+ + LSHN I  ++GL++++ L ++++  N+I ++  + ++  L
Sbjct: 270 IEKITGLEDLKALQIVDLSHNQISSLQGLENHDFLEVINLEDNKIAELGEIEYIENL 326



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 49/189 (25%), Positives = 94/189 (49%)
 Frame = +1

Query: 460  LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIEN 639
            L+ LD+S N +  +  V  +  L +L   +NK+    N    + L+ ++   N+I  + +
Sbjct: 151  LQKLDLSVNKIEDLSCVSYMPYLLELNASHNKLTTFFNFKPPKNLKKVDFSYNQISEMRD 210

Query: 640  VDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNG 819
            +     L  L L  N+I ++  L+  + LT LS+  NR+T I GL  ++ ++ L LS+N 
Sbjct: 211  LSAYQALTKLILDNNEIEEISGLELCSGLTHLSLAKNRITTINGL-GILPIKILCLSNNQ 269

Query: 820  IEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSL 999
            IE I GL+    L ++D++ N+I  ++ + +   L+   + DN +    ++   +    L
Sbjct: 270  IEKITGLEDLKALQIVDLSHNQISSLQGLENHDFLEVINLEDNKIAELGEIEYIENLPLL 329

Query: 1000 ETVYLERTP 1026
              +   R P
Sbjct: 330  RVLNFLRNP 338



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 48/174 (27%), Positives = 80/174 (45%)
 Frame = +1

Query: 451 LTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRA 630
           L E  + +    L RS  G +++     L L N  +  I  L     LQ L+L  N+I  
Sbjct: 106 LREEVVANALHQLGRSGSGTEQV--YLNLVLSNCDLIDISILCEYVHLQKLDLSVNKIED 163

Query: 631 IENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLS 810
           +  V  +  L  L    NK+T   N     NL  +    N+++++  L +   L +L L 
Sbjct: 164 LSCVSYMPYLLELNASHNKLTTFFNFKPPKNLKKVDFSYNQISEMRDLSAYQALTKLILD 223

Query: 811 HNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
           +N IE I GL+  + LT L +A NRI  I  +  +  ++   +++N +E  + L
Sbjct: 224 NNEIEEISGLELCSGLTHLSLAKNRITTINGLG-ILPIKILCLSNNQIEKITGL 276



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 37/124 (29%), Positives = 63/124 (50%), Gaps = 6/124 (4%)
 Frame = +1

Query: 289 RIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEI 468
           RI  I G  +L  +K LCL  N I+ I  LE L++L+ +DL  NQI  ++ LE    LE+
Sbjct: 248 RITTINGLGIL-PIKILCLSNNQIEKITGLEDLKALQIVDLSHNQISSLQGLENHDFLEV 306

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSS------LRQLQMLELGSNRIRA 630
           +++  N +  +  ++ +  L  L ++N   N I+  +          L++ EL   +I+ 
Sbjct: 307 INLEDNKIAELGEIEYIENLPLLRVLNFLRNPIQEKAEYWFFVIFMLLRLTELDQKKIKV 366

Query: 631 IENV 642
            E V
Sbjct: 367 EEKV 370


>ref|XP_536764.2| PREDICTED: similar to leucine rich repeat containing 50 [Canis
           familiaris].
          Length = 762

 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 63/167 (37%), Positives = 89/167 (53%), Gaps = 7/167 (4%)
 Frame = +1

Query: 334 TLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVD 513
           TL L       IENLE    LR L L  N I+KIENLEA TEL  L +  NLL  IE ++
Sbjct: 236 TLYLHFKGFNRIENLEEYTGLRCLWLECNGIQKIENLEAQTELRCLFLQVNLLHKIENLE 295

Query: 514 KLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTL---TNLESLFLGKN 684
            L +L  L L NN I  IENLS L  L  L++  N +  +E++  L     L  L L  N
Sbjct: 296 SLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLETVEDIQHLKECLKLCVLDLSHN 355

Query: 685 KITK---LQNLDALTNLTVLSMQSNRLTK-IEGLQSLVNLRELYLSH 813
           K++    L  L+++ +L VL++  N + + I   +  V +R  +L++
Sbjct: 356 KLSDPEILSVLESMPDLRVLNLMGNPVIRHIANYRKTVTVRLKHLTY 402



 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 46/135 (34%), Positives = 74/135 (54%), Gaps = 3/135 (2%)
 Frame = +1

Query: 535 LFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDA 714
           L+L     N+IENL     L+ L L  N I+ IEN++  T L  LFL  N + K++NL++
Sbjct: 237 LYLHFKGFNRIENLEEYTGLRCLWLECNGIQKIENLEAQTELRCLFLQVNLLHKIENLES 296

Query: 715 LTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNN---KLTMLDIASNR 885
           L  L  L++ +N +  IE L  L  L  L ++HN +E +E +       KL +LD++ N+
Sbjct: 297 LQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLETVEDIQHLKECLKLCVLDLSHNK 356

Query: 886 IKKIENVSHLTELQE 930
           +   E +S L  + +
Sbjct: 357 LSDPEILSVLESMPD 371



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 58/171 (33%), Positives = 89/171 (52%), Gaps = 15/171 (8%)
 Frame = +1

Query: 463 EILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENV 642
           + L + F     IE +++ T L+ L+L  N I KIENL +  +L+ L L  N +  IEN+
Sbjct: 235 DTLYLHFKGFNRIENLEEYTGLRCLWLECNGIQKIENLEAQTELRCLFLQVNLLHKIENL 294

Query: 643 DTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSL---VNLRELYLSH 813
           ++L  L++L L  N I  ++NL  L  L  L M  N L  +E +Q L   + L  L LSH
Sbjct: 295 ESLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLETVEDIQHLKECLKLCVLDLSH 354

Query: 814 NGI---EVIEGLDSNNKLTMLDIASNR-IKKIEN--------VSHLTELQE 930
           N +   E++  L+S   L +L++  N  I+ I N        + HLT L +
Sbjct: 355 NKLSDPEILSVLESMPDLRVLNLMGNPVIRHIANYRKTVTVRLKHLTYLDD 405



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 45/133 (33%), Positives = 76/133 (57%), Gaps = 4/133 (3%)
 Frame = +1

Query: 283 HYR-IGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTE 459
           H++   +IE  E    ++ L L  N I+ IENLEA   LR L L  N + KIENLE+L +
Sbjct: 240 HFKGFNRIENLEEYTGLRCLWLECNGIQKIENLEAQTELRCLFLQVNLLHKIENLESLQK 299

Query: 460 LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQ---LQMLELGSNRIRA 630
           L+ L++S N +++IE +  L  L  L + +N +  +E++  L++   L +L+L  N++  
Sbjct: 300 LDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLETVEDIQHLKECLKLCVLDLSHNKLSD 359

Query: 631 IENVDTLTNLESL 669
            E +  L ++  L
Sbjct: 360 PEILSVLESMPDL 372



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 38/104 (36%), Positives = 60/104 (57%)
 Frame = +1

Query: 661 ESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGL 840
           ++L+L      +++NL+  T L  L ++ N + KIE L++   LR L+L  N +  IE L
Sbjct: 235 DTLYLHFKGFNRIENLEEYTGLRCLWLECNGIQKIENLEAQTELRCLFLQVNLLHKIENL 294

Query: 841 DSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
           +S  KL  L++++N IK IEN+S L  L    M  N LE+  D+
Sbjct: 295 ESLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLETVEDI 338


>ref|XP_850685.1| PREDICTED: similar to leucine-rich repeats and IQ motif containing
           2 [Canis familiaris].
          Length = 852

 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 60/194 (30%), Positives = 90/194 (46%)
 Frame = +1

Query: 349 QNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRL 528
           Q L K   NL     +  L L  NQI K+ENLE    L  L ++ N L  + GV KLT+L
Sbjct: 23  QGLQKLSPNLPCEADIHTLILDKNQIIKLENLEKCRRLIQLSVANNRLVRMMGVAKLTQL 82

Query: 529 KKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNL 708
           + L L +N I  +E L  L  L+ L L  N ++A+E + +   L+ L L  N I ++ +L
Sbjct: 83  RVLNLPHNSIGYVEGLKDLVHLEWLNLAGNNLKAMEQISSCAALQHLDLSDNNIPQIGDL 142

Query: 709 DALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRI 888
             L +L  L +  N +T +        +   YL  +             L +L +A N I
Sbjct: 143 SKLVSLKTLLLHGNIITSL-------RMAPAYLPRS-------------LAILSLAENEI 182

Query: 889 KKIENVSHLTELQE 930
           + +  +S L  L E
Sbjct: 183 RDLNEISFLASLTE 196



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 41/112 (36%), Positives = 62/112 (55%)
 Frame = +1

Query: 637 NVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHN 816
           N+    ++ +L L KN+I KL+NL+    L  LS+ +NRL ++ G+  L  LR L L HN
Sbjct: 31  NLPCEADIHTLILDKNQIIKLENLEKCRRLIQLSVANNRLVRMMGVAKLTQLRVLNLPHN 90

Query: 817 GIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            I  +EGL     L  L++A N +K +E +S    LQ   ++DN +    DL
Sbjct: 91  SIGYVEGLKDLVHLEWLNLAGNNLKAMEQISSCAALQHLDLSDNNIPQIGDL 142



 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 39/130 (30%), Positives = 71/130 (54%)
 Frame = +1

Query: 571 NLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 750
           NL     +  L L  N+I  +EN++    L  L +  N++ ++  +  LT L VL++  N
Sbjct: 31  NLPCEADIHTLILDKNQIIKLENLEKCRRLIQLSVANNRLVRMMGVAKLTQLRVLNLPHN 90

Query: 751 RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQE 930
            +  +EGL+ LV+L  L L+ N ++ +E + S   L  LD++ N I +I ++S L  L+ 
Sbjct: 91  SIGYVEGLKDLVHLEWLNLAGNNLKAMEQISSCAALQHLDLSDNNIPQIGDLSKLVSLKT 150

Query: 931 FWMNDNLLES 960
             ++ N++ S
Sbjct: 151 LLLHGNIITS 160



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 39/121 (32%), Positives = 65/121 (53%), Gaps = 5/121 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           ++L H  IG +EG + L  ++ L L  N +K +E + +  +L+ LDL DN I +I +L  
Sbjct: 85  LNLPHNSIGYVEGLKDLVHLEWLNLAGNNLKAMEQISSCAALQHLDLSDNNIPQIGDLSK 144

Query: 451 LTELEILDISFNLLRSIEGVDKL--TRLKKLFLVNNKI---NKIENLSSLRQLQMLELGS 615
           L  L+ L +  N++ S+          L  L L  N+I   N+I  L+SL +L+ L + +
Sbjct: 145 LVSLKTLLLHGNIITSLRMAPAYLPRSLAILSLAENEIRDLNEISFLASLTELEQLSIMN 204

Query: 616 N 618
           N
Sbjct: 205 N 205


>ref|XP_536663.2| PREDICTED: similar to leucine rich repeat containing 48 [Canis
           familiaris].
          Length = 506

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 50/122 (40%), Positives = 80/122 (65%), Gaps = 3/122 (2%)
 Frame = +1

Query: 349 QNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRL 528
           QN+++ I++L   ++L +L L +N I KIE LE L  L  LD+SFN + +IEG+D L  L
Sbjct: 53  QNILR-IDSLWEFENLTKLQLDNNIIEKIEGLEQLVHLVWLDLSFNNIEAIEGLDTLVNL 111

Query: 529 KKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTL---TNLESLFLGKNKITKL 699
           + L L NN+I+KI++L +L +LQ+L LG+N+I  + N+  L    +L +L L  N I + 
Sbjct: 112 EDLSLFNNRISKIDSLDALVKLQVLSLGNNQIGNMMNIIYLRRFKDLRTLSLSGNPIAES 171

Query: 700 QN 705
           ++
Sbjct: 172 ED 173



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 62/174 (35%), Positives = 87/174 (50%), Gaps = 10/174 (5%)
 Frame = +1

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDT 648
           L + F  +  I+ + +   L KL L NN I KIE L  L  L  L+L  N I AIE +DT
Sbjct: 48  LRLDFQNILRIDSLWEFENLTKLQLDNNIIEKIEGLEQLVHLVWLDLSFNNIEAIEGLDT 107

Query: 649 LTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNR---LTKIEGLQSLVNLRELYLSHNG 819
           L NLE L L  N+I+K+ +LDAL  L VLS+ +N+   +  I  L+   +LR L LS N 
Sbjct: 108 LVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNQIGNMMNIIYLRRFKDLRTLSLSGNP 167

Query: 820 IEVIEGLDS-----NNKLTMLDI--ASNRIKKIENVSHLTELQEFWMNDNLLES 960
           I   E            L  LD     + +K++    H   + E    +NL++S
Sbjct: 168 IAESEDYKMFVCAYLPDLVYLDFHRIDDHMKEMAESKHQYSIDELKHRENLIQS 221



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 44/121 (36%), Positives = 68/121 (56%)
 Frame = +1

Query: 664  SLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLD 843
            SL L    I ++ +L    NLT L + +N + KIEGL+ LV+L  L LS N IE IEGLD
Sbjct: 47   SLRLDFQNILRIDSLWEFENLTKLQLDNNIIEKIEGLEQLVHLVWLDLSFNNIEAIEGLD 106

Query: 844  SNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERT 1023
            +   L  L + +NRI KI+++  L +LQ   + +N + +  ++   +  + L T+ L   
Sbjct: 107  TLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNQIGNMMNIIYLRRFKDLRTLSLSGN 166

Query: 1024 P 1026
            P
Sbjct: 167  P 167



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 3/124 (2%)
 Frame = +1

Query: 424 IRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQML 603
           I +I++L     L  L +  N++  IEG+++L  L  L L  N I  IE L +L  L+ L
Sbjct: 55  ILRIDSLWEFENLTKLQLDNNIIEKIEGLEQLVHLVWLDLSFNNIEAIEGLDTLVNLEDL 114

Query: 604 ELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN---LDALTNLTVLSMQSNRLTKIEGL 774
            L +NRI  I+++D L  L+ L LG N+I  + N   L    +L  LS+  N + + E  
Sbjct: 115 SLFNNRISKIDSLDALVKLQVLSLGNNQIGNMMNIIYLRRFKDLRTLSLSGNPIAESEDY 174

Query: 775 QSLV 786
           +  V
Sbjct: 175 KMFV 178



 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 47/123 (38%), Positives = 65/123 (52%), Gaps = 3/123 (2%)
 Frame = +1

Query: 280 NHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTE 459
           N  RI  +  FE L K++   L  N+I+ IE LE L  L  LDL  N I  IE L+ L  
Sbjct: 54  NILRIDSLWEFENLTKLQ---LDNNIIEKIEGLEQLVHLVWLDLSFNNIEAIEGLDTLVN 110

Query: 460 LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQ---LQMLELGSNRIRA 630
           LE L +  N +  I+ +D L +L+ L L NN+I  + N+  LR+   L+ L L  N I  
Sbjct: 111 LEDLSLFNNRISKIDSLDALVKLQVLSLGNNQIGNMMNIIYLRRFKDLRTLSLSGNPIAE 170

Query: 631 IEN 639
            E+
Sbjct: 171 SED 173


>ref|XP_541218.2| PREDICTED: similar to Platelet glycoprotein V precursor (GPV)
           (CD42D) [Canis familiaris].
          Length = 512

 Score = 78.6 bits (192), Expect = 9e-15
 Identities = 63/224 (28%), Positives = 117/224 (52%), Gaps = 8/224 (3%)
 Frame = +1

Query: 310 FEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIE--NLEALTELEILDISF 483
           F++L  +KTL L +N ++C+ ++    SL  L L DN I  +   + E L +L+IL++  
Sbjct: 91  FKMLSTLKTLELWKNKLRCVPSILPA-SLEVLKLNDNSIDVLHGSDFEGLKKLKILELKN 149

Query: 484 NLLRSIE--GVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIEN--VDTL 651
           NL+ S+    +  L  L+ L L  N I  +    +L  L+ + + +N++  I      +L
Sbjct: 150 NLISSLSPSSLSSLVSLQSLVLDGNNIESVAGPLALPHLRSMSMENNKLHLIPAGFFTSL 209

Query: 652 TNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRL--TKIEGLQSLVNLRELYLSHNGIE 825
            +L+ L    N +TK+  +D   +L  L M+ N+L   +   ++ L NL  LYLS N + 
Sbjct: 210 QSLQFLSFSGNFLTKIP-IDLPKSLLSLKMERNQLKVVRFRDMKHLENLSHLYLSENSLS 268

Query: 826 VIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLE 957
            I+G+     LT L+++ N++  +        LQ+  +++NL++
Sbjct: 269 SIDGVQILANLTTLELSQNQVPVLP-FRLPARLQKLDISNNLIQ 311


>ref|XP_531654.2| PREDICTED: similar to leucine-rich repeats and immunoglobulin-like
            domains 3 [Canis familiaris].
          Length = 1046

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 88/274 (32%), Positives = 139/274 (50%), Gaps = 20/274 (7%)
 Frame = +1

Query: 256  RDAEDVDLNHYRIGKIEGF-EVLRKVKTLCLRQNLIKCI--ENLEALQSLRELDLYDNQI 426
            ++  +V LN+  +  I     V   +  L L  N I  I  E+L+  QSL  LDL  N I
Sbjct: 25   QNLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKQFQSLETLDLSSNNI 84

Query: 427  RKIENLEALTELEILDISFNLLRSIEG--VDKLTR-LKKLFLVNNKINKI-ENLSSLRQL 594
             +++      +L+ L I+ N + S+E    D L   L  L L  N+I+ I   +  L QL
Sbjct: 85   SELKTPLPPLQLKYLYINSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQL 144

Query: 595  QMLELGSNRIRAIENVDTLT-----NLESLFLGKNKITKLQN--LDALTNLTVLSMQSNR 753
            Q LEL  N+I+   NVD LT      L+SL + +N +TKL +     L+N+ VL +  N 
Sbjct: 145  QHLELNRNKIK---NVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEVLQLDHNN 201

Query: 754  LTKIE--GLQSLVNLRELYLSHNGIEVI--EGLDSNNKLTMLDIASNRIKKIENVSH--L 915
            LT+I    L  L+ L+EL+LS N I  I  +  +   KL+ LD+  N + ++++ S   L
Sbjct: 202  LTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGL 261

Query: 916  TELQEFWMNDNLLESWSDLX*AQGAQSLETVYLE 1017
            + L    + +N +   +D    +G  SL+T+ L+
Sbjct: 262  SLLNTLHIGNNKVSYIADCA-FRGLSSLKTLDLK 294


>ref|XP_867175.1| PREDICTED: similar to T-cell activation leucine repeat-rich protein
            isoform 2 [Canis familiaris].
          Length = 793

 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 75/234 (32%), Positives = 121/234 (51%), Gaps = 13/234 (5%)
 Frame = +1

Query: 298  KIEGFEVLRKVKTLCLRQNLIKCIENL-EALQSLRELDLYDNQIRK---IENLEALTELE 465
            ++EGF+ L+ ++TL L+ +L +  + + + L SL++L L DN+  K   + NL+ +  L+
Sbjct: 520  QLEGFQDLKNLRTLYLKSSLSRIPQVITDLLPSLQKLAL-DNEGSKLVVLNNLKKMVNLK 578

Query: 466  ILD-ISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQ---MLELGSNRIRAI 633
             L+ IS +L R    +  L  L +L L  N +  +E + S + LQ    L+L  N I  I
Sbjct: 579  SLELISCDLERIPHSIFSLNNLHELDLKENNLKTVEEIISFQHLQNLSCLKLWHNNIAYI 638

Query: 634  -ENVDTLTNLESLFLGKNKITKLQ-NLDALTNLTVLSMQSNRLTKI-EGLQSLVNLRELY 804
               +  L+NLE L L  N I  L   L   T L  L +  N LT I E +Q L NL+   
Sbjct: 639  PAQIGALSNLEQLSLNHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFA 698

Query: 805  LSHNGIEVI-EGLDSNNKLTMLDIASNRIKKIE-NVSHLTELQEFWMNDNLLES 960
            +++N IE++ +GL    KL  L +  N +  +  +V  L+ L    +  N LE+
Sbjct: 699  VTNNNIEMLPDGLFQCKKLQCLLLGKNSLMSLSPHVGELSNLTHLELIGNYLET 752


  Database: RefSeq49_CP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,874,504
  Number of sequences in database:  33,336
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33336
Number of Hits to DB: 32,708,343
Number of extensions: 783549
Number of successful extensions: 3526
Number of sequences better than 1.0e-05: 79
Number of HSP's gapped: 3347
Number of HSP's successfully gapped: 162
Length of query: 346
Length of database: 18,874,504
Length adjustment: 104
Effective length of query: 242
Effective length of database: 15,407,560
Effective search space: 3728629520
Effective search space used: 3728629520
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007857
         (1040 letters)

Database: RefSeq49_SP.fasta 
           24,897 sequences; 11,343,932 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_001230831.1| protein phosphatase 1, regulatory (inhibitor...   548   e-156
Alignment   gi|XP_001928516.1| PREDICTED: leucine-rich repeat-containing pr...   101   8e-22
Alignment   gi|XP_003134708.2| PREDICTED: leucine-rich repeat and guanylate...    85   8e-17
Alignment   gi|XP_003132746.2| PREDICTED: LOW QUALITY PROTEIN: centrosomal ...    82   4e-16
Alignment   gi|XP_003126886.1| PREDICTED: leucine-rich repeat-containing pr...    82   4e-16
Alignment   gi|XP_003353284.1| PREDICTED: slit homolog 3 protein-like [Sus ...    80   2e-15
Alignment   gi|XP_003121288.1| PREDICTED: insulin-like growth factor-bindin...    80   2e-15
Alignment   gi|XP_001926121.1| PREDICTED: leucine-rich repeat-containing pr...    78   7e-15
Alignment   gi|XP_003355739.1| PREDICTED: leucine-rich repeat and IQ domain...    76   4e-14
Alignment   gi|XP_003355547.1| PREDICTED: leucine-rich repeats and immunogl...    74   1e-13

>ref|NP_001230831.1| protein phosphatase 1, regulatory (inhibitor) subunit 7 [Sus scrofa].
          Length = 360

 Score =  548 bits (1411), Expect = e-156
 Identities = 293/335 (87%), Positives = 297/335 (88%)
 Frame = +1

Query: 31   MAAERGTGQQQSQEMMEVDRRVXXXXXXXXXXXXXXXXIVADLSEHSLKDXXXXXXXXXX 210
            MAAERGTGQQQSQEMMEVDRRV                IVADLSEHSLKD          
Sbjct: 1    MAAERGTGQQQSQEMMEVDRRVESEESGDEEGKKQSSGIVADLSEHSLKDGEERGHEEPE 60

Query: 211  XXXXXXVDMETINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQ 390
                  VDMETINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCI NLEALQ
Sbjct: 61   EGQEPPVDMETINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIGNLEALQ 120

Query: 391  SLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIE 570
            SLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIE
Sbjct: 121  SLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIE 180

Query: 571  NLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 750
            NLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN
Sbjct: 181  NLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 240

Query: 751  RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQE 930
            RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQE
Sbjct: 241  RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQE 300

Query: 931  FWMNDNLLESWSDLX*AQGAQSLETVYLERTPCRR 1035
            FWMNDNLLESWSDL   +GA+SLETVYLER P ++
Sbjct: 301  FWMNDNLLESWSDLDELKGAKSLETVYLERNPLQK 335



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 40/111 (36%), Positives = 62/111 (55%)
 Frame = +1

Query: 289 RIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEI 468
           R+ KIEG + L  ++ L L  N I+ IE L++   L  LD+  N+I+KIEN+  LTEL+ 
Sbjct: 241 RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQE 300

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNR 621
             ++ NLL S   +D+L   K L  V  + N ++     R+  +L L + R
Sbjct: 301 FWMNDNLLESWSDLDELKGAKSLETVYLERNPLQKDPQYRRKILLALPTVR 351


>ref|XP_001928516.1| PREDICTED: leucine-rich repeat-containing protein 49 [Sus scrofa].
          Length = 685

 Score =  101 bits (251), Expect = 8e-22
 Identities = 68/212 (32%), Positives = 109/212 (51%), Gaps = 3/212 (1%)
 Frame = +1

Query: 346 RQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTR 525
           RQ L  C   ++  + LR L+   N I +I+N+  L  L  LD+  N +  I G+  L  
Sbjct: 99  RQKLTVC-PIIDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLRS 157

Query: 526 LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
           L+ L L  N+I KI NL +L+ L +L+L  N+I  IENV+ L +L  L L +N ++ + N
Sbjct: 158 LRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDN 217

Query: 706 LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEG---LDSNNKLTMLDIA 876
           L+ L +LT L+++ N++T +  + +L  L+ L+LS N I   E    L  +  L+ +   
Sbjct: 218 LNGLDSLTELNLRHNQITFVRDVDNLPCLQRLFLSFNNISTFESVCCLADSTSLSDITFD 277

Query: 877 SNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            N I            QE W    +L++   L
Sbjct: 278 GNPI-----------AQESWYKHTILQNMMQL 298



 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 56/173 (32%), Positives = 100/173 (57%)
 Frame = +1

Query: 508  VDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNK 687
            +D    L+ L   +N I +I+N+S+L++L  L+L  N+I  I  + TL +L  L LGKN+
Sbjct: 108  IDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLRSLRVLLLGKNR 167

Query: 688  ITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTML 867
            I K+ NL+ L +L VL +  N++TKIE +  L +LR L L+ N +  ++ L+  + LT L
Sbjct: 168  IKKISNLENLKSLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTEL 227

Query: 868  DIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERTP 1026
            ++  N+I  + +V +L  LQ  +++ N + ++  +     + SL  +  +  P
Sbjct: 228  NLRHNQITFVRDVDNLPCLQRLFLSFNNISTFESVCCLADSTSLSDITFDGNP 280



 Score = 91.3 bits (225), Expect = 8e-19
 Identities = 63/185 (34%), Positives = 102/185 (55%), Gaps = 8/185 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           ++  H  I +I+    L+++  L L  N I+ I  L  L+SLR L L  N+I+KI NLE 
Sbjct: 117 LNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLRSLRVLLLGKNRIKKISNLEN 176

Query: 451 LTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRA 630
           L  L++LD+  N +  IE V+ L  L+ L L  N ++ ++NL+ L  L  L L  N+I  
Sbjct: 177 LKSLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQITF 236

Query: 631 IENVDTLTNLESLFLGKNKITKLQNLDAL---TNLTVLSMQSNRLT-----KIEGLQSLV 786
           + +VD L  L+ LFL  N I+  +++  L   T+L+ ++   N +      K   LQ+++
Sbjct: 237 VRDVDNLPCLQRLFLSFNNISTFESVCCLADSTSLSDITFDGNPIAQESWYKHTILQNMM 296

Query: 787 NLREL 801
            LR+L
Sbjct: 297 QLRQL 301



 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 43/124 (34%), Positives = 67/124 (54%)
 Frame = +1

Query: 601 LELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQS 780
           L L   ++     +D   +L  L    N IT++QN+  L  L  L +  N++ +I GL +
Sbjct: 95  LTLERQKLTVCPIIDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLST 154

Query: 781 LVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
           L +LR L L  N I+ I  L++   L +LD+  N+I KIENV+HL +L+   +  NLL  
Sbjct: 155 LRSLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSH 214

Query: 961 WSDL 972
             +L
Sbjct: 215 VDNL 218



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 47/154 (30%), Positives = 76/154 (49%)
 Frame = +1

Query: 487 LLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLES 666
           L RS E  +K+    +L L   K+     +     L++L    N I  I+N+  L  L  
Sbjct: 81  LQRSSE--EKILYSDRLTLERQKLTVCPIIDGEEHLRLLNFQHNFITRIQNISNLQRLIF 138

Query: 667 LFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDS 846
           L L  N+I ++  L  L +L VL +  NR+ KI  L++L +L  L L  N I  IE ++ 
Sbjct: 139 LDLYDNQIEEISGLSTLRSLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENVNH 198

Query: 847 NNKLTMLDIASNRIKKIENVSHLTELQEFWMNDN 948
              L +L++A N +  ++N++ L  L E  +  N
Sbjct: 199 LCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHN 232


>ref|XP_003134708.2| PREDICTED: leucine-rich repeat and guanylate kinase
           domain-containing protein [Sus scrofa].
          Length = 831

 Score = 84.7 bits (208), Expect = 8e-17
 Identities = 54/177 (30%), Positives = 99/177 (55%)
 Frame = +1

Query: 394 LRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIEN 573
           L++L+L  N+I  +  +  +  L  L+ S N L +         LKK+    N+I+++ +
Sbjct: 159 LQKLNLAGNKIEDLSCVSCMPYLLELNASQNKLTAFFNFKPPKNLKKVDFSYNQISEMCD 218

Query: 574 LSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNR 753
           LS+ + L  L L SN I  I  ++  ++L  L L KNKIT +  L  L  + +L + +N+
Sbjct: 219 LSAYQTLTKLILDSNEIAEITGLEMCSSLTHLSLAKNKITAINGLGMLP-IKILCLSNNQ 277

Query: 754 LTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTEL 924
           + KI GL  L  L+ L LSHN I  ++GL+S++ L ++++  N++ ++  + ++  L
Sbjct: 278 IEKITGLDELRVLQILDLSHNQITSLQGLESHDFLEVINLEDNKVAELSEIEYIENL 334



 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 57/212 (26%), Positives = 103/212 (48%)
 Frame = +1

Query: 391  SLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIE 570
            +L  LDL D  I     L     L+ L+++ N +  +  V  +  L +L    NK+    
Sbjct: 141  NLSGLDLIDISI-----LCGYIHLQKLNLAGNKIEDLSCVSCMPYLLELNASQNKLTAFF 195

Query: 571  NLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 750
            N    + L+ ++   N+I  + ++     L  L L  N+I ++  L+  ++LT LS+  N
Sbjct: 196  NFKPPKNLKKVDFSYNQISEMCDLSAYQTLTKLILDSNEIAEITGLEMCSSLTHLSLAKN 255

Query: 751  RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQE 930
            ++T I GL  ++ ++ L LS+N IE I GLD    L +LD++ N+I  ++ +     L+ 
Sbjct: 256  KITAINGL-GMLPIKILCLSNNQIEKITGLDELRVLQILDLSHNQITSLQGLESHDFLEV 314

Query: 931  FWMNDNLLESWSDLX*AQGAQSLETVYLERTP 1026
              + DN +   S++   +    L  + L R P
Sbjct: 315  INLEDNKVAELSEIEYIENLPLLRVLSLLRNP 346



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 40/124 (32%), Positives = 65/124 (52%), Gaps = 6/124 (4%)
 Frame = +1

Query: 289 RIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEI 468
           +I  I G  +L  +K LCL  N I+ I  L+ L+ L+ LDL  NQI  ++ LE+   LE+
Sbjct: 256 KITAINGLGML-PIKILCLSNNQIEKITGLDELRVLQILDLSHNQITSLQGLESHDFLEV 314

Query: 469 LDISFNL---LRSIEGVDKLTRLKKLFLVNNKINKIENLSS---LRQLQMLELGSNRIRA 630
           +++  N    L  IE ++ L  L+ L L+ N I +  +  S      L++ +L   +I+ 
Sbjct: 315 INLEDNKVAELSEIEYIENLPLLRVLSLLRNPIQEKSDYWSFVIFMLLRLTDLDQRKIKV 374

Query: 631 IENV 642
            E V
Sbjct: 375 EEKV 378



 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 46/174 (26%), Positives = 78/174 (44%)
 Frame = +1

Query: 451 LTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRA 630
           L E  + +  + L RS  G +++     L L    +  I  L     LQ L L  N+I  
Sbjct: 114 LREEVVAEKLYQLGRSGSGTEQV--YLSLNLSGLDLIDISILCGYIHLQKLNLAGNKIED 171

Query: 631 IENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLS 810
           +  V  +  L  L   +NK+T   N     NL  +    N+++++  L +   L +L L 
Sbjct: 172 LSCVSCMPYLLELNASQNKLTAFFNFKPPKNLKKVDFSYNQISEMCDLSAYQTLTKLILD 231

Query: 811 HNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            N I  I GL+  + LT L +A N+I  I  +  L  ++   +++N +E  + L
Sbjct: 232 SNEIAEITGLEMCSSLTHLSLAKNKITAINGLGML-PIKILCLSNNQIEKITGL 284


>ref|XP_003132746.2| PREDICTED: LOW QUALITY PROTEIN: centrosomal protein of 97 kDa-like
           [Sus scrofa].
          Length = 861

 Score = 82.4 bits (202), Expect = 4e-16
 Identities = 62/194 (31%), Positives = 91/194 (46%)
 Frame = +1

Query: 349 QNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRL 528
           Q L K   NL     +  L L  NQI K+ENLE    L  L ++ N L  + GV KLT+L
Sbjct: 23  QGLQKLSPNLPCEVDIHTLILDKNQIIKLENLEKYKRLIQLSVANNRLVRMMGVAKLTQL 82

Query: 529 KKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNL 708
           + L L +N I  +E L  L  L+ L L  N ++A+E +++ T L+ L L  N I ++ +L
Sbjct: 83  RVLNLPHNSIGYVEGLKELVHLEWLNLAGNNLKAMEQLNSCTALQHLDLSDNNIPQIGDL 142

Query: 709 DALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRI 888
             L +L  L +  N +T +        +   YL                L +L +A N I
Sbjct: 143 SKLISLKTLLLHGNIITSL-------RMAPAYLP-------------RCLAILSLAENEI 182

Query: 889 KKIENVSHLTELQE 930
           + +  VS L  L E
Sbjct: 183 RDLNEVSFLASLTE 196



 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 41/112 (36%), Positives = 63/112 (56%)
 Frame = +1

Query: 637 NVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHN 816
           N+    ++ +L L KN+I KL+NL+    L  LS+ +NRL ++ G+  L  LR L L HN
Sbjct: 31  NLPCEVDIHTLILDKNQIIKLENLEKYKRLIQLSVANNRLVRMMGVAKLTQLRVLNLPHN 90

Query: 817 GIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            I  +EGL     L  L++A N +K +E ++  T LQ   ++DN +    DL
Sbjct: 91  SIGYVEGLKELVHLEWLNLAGNNLKAMEQLNSCTALQHLDLSDNNIPQIGDL 142



 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 40/130 (30%), Positives = 72/130 (55%)
 Frame = +1

Query: 571 NLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 750
           NL     +  L L  N+I  +EN++    L  L +  N++ ++  +  LT L VL++  N
Sbjct: 31  NLPCEVDIHTLILDKNQIIKLENLEKYKRLIQLSVANNRLVRMMGVAKLTQLRVLNLPHN 90

Query: 751 RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQE 930
            +  +EGL+ LV+L  L L+ N ++ +E L+S   L  LD++ N I +I ++S L  L+ 
Sbjct: 91  SIGYVEGLKELVHLEWLNLAGNNLKAMEQLNSCTALQHLDLSDNNIPQIGDLSKLISLKT 150

Query: 931 FWMNDNLLES 960
             ++ N++ S
Sbjct: 151 LLLHGNIITS 160



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 41/121 (33%), Positives = 67/121 (55%), Gaps = 5/121 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           ++L H  IG +EG + L  ++ L L  N +K +E L +  +L+ LDL DN I +I +L  
Sbjct: 85  LNLPHNSIGYVEGLKELVHLEWLNLAGNNLKAMEQLNSCTALQHLDLSDNNIPQIGDLSK 144

Query: 451 LTELEILDISFNLLRSIEGVDK-LTR-LKKLFLVNNKI---NKIENLSSLRQLQMLELGS 615
           L  L+ L +  N++ S+      L R L  L L  N+I   N++  L+SL +L+ L + +
Sbjct: 145 LISLKTLLLHGNIITSLRMAPAYLPRCLAILSLAENEIRDLNEVSFLASLTELEQLSIMN 204

Query: 616 N 618
           N
Sbjct: 205 N 205


>ref|XP_003126886.1| PREDICTED: leucine-rich repeat-containing protein 50-like [Sus
           scrofa].
          Length = 639

 Score = 82.4 bits (202), Expect = 4e-16
 Identities = 59/156 (37%), Positives = 87/156 (55%), Gaps = 7/156 (4%)
 Frame = +1

Query: 367 IENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLV 546
           IENL+    LR L L  N I+KIENLEA TEL  L +  NLL  IE ++ L +L  L L 
Sbjct: 122 IENLDEYTGLRCLWLECNGIQKIENLEAQTELRCLFLQVNLLHKIENLEPLQKLDALNLS 181

Query: 547 NNKINKIENLSSLRQLQMLELGSNRIRAIENVDTL---TNLESLFLGKNKITK---LQNL 708
           NN I  IENLS L  L  L++  N +  ++++  L     L  L L  NK++    L  L
Sbjct: 182 NNYIKTIENLSCLPVLNTLQMAHNHLETVQDIQHLKECLKLCVLDLSHNKLSDPEILSVL 241

Query: 709 DALTNLTVLSMQSNRLTK-IEGLQSLVNLRELYLSH 813
           +++ +L VL++  N +T+ I   +  V +R  +L++
Sbjct: 242 ESMADLRVLNLMGNPVTRTIPNYRRTVTVRLKHLTY 277



 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 51/150 (34%), Positives = 80/150 (53%), Gaps = 6/150 (4%)
 Frame = +1

Query: 463 EILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENV 642
           + L + F     IE +D+ T L+ L+L  N I KIENL +  +L+ L L  N +  IEN+
Sbjct: 110 DTLYLHFKGFDRIENLDEYTGLRCLWLECNGIQKIENLEAQTELRCLFLQVNLLHKIENL 169

Query: 643 DTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSL---VNLRELYLSH 813
           + L  L++L L  N I  ++NL  L  L  L M  N L  ++ +Q L   + L  L LSH
Sbjct: 170 EPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLETVQDIQHLKECLKLCVLDLSH 229

Query: 814 NGI---EVIEGLDSNNKLTMLDIASNRIKK 894
           N +   E++  L+S   L +L++  N + +
Sbjct: 230 NKLSDPEILSVLESMADLRVLNLMGNPVTR 259



 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 48/137 (35%), Positives = 77/137 (56%), Gaps = 6/137 (4%)
 Frame = +1

Query: 430 KIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLEL 609
           +IENL+  T L  L +  N ++ IE ++  T L+ LFL  N ++KIENL  L++L  L L
Sbjct: 121 RIENLDEYTGLRCLWLECNGIQKIENLEAQTELRCLFLQVNLLHKIENLEPLQKLDALNL 180

Query: 610 GSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDAL---TNLTVLSMQSNRLTK---IEG 771
            +N I+ IEN+  L  L +L +  N +  +Q++  L     L VL +  N+L+    +  
Sbjct: 181 SNNYIKTIENLSCLPVLNTLQMAHNHLETVQDIQHLKECLKLCVLDLSHNKLSDPEILSV 240

Query: 772 LQSLVNLRELYLSHNGI 822
           L+S+ +LR L L  N +
Sbjct: 241 LESMADLRVLNLMGNPV 257



 Score = 72.4 bits (176), Expect = 4e-13
 Identities = 61/180 (33%), Positives = 84/180 (46%), Gaps = 4/180 (2%)
 Frame = +1

Query: 511  DKLTRLKKLFLVNNKINKIENLSSLRQLQ-MLELGSNRIRAIENVDTLTNLESLFLGKNK 687
            D+  R+ K FL   K+ K   L     L   L L       IEN+D  T L  L+L  N 
Sbjct: 83   DRGPRMTKTFL--RKLCKQHKLYMTPALNDTLYLHFKGFDRIENLDEYTGLRCLWLECNG 140

Query: 688  ITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTML 867
            I K++NL+A T L  L +Q N L KIE L+ L  L  L LS+N I+ IE L     L  L
Sbjct: 141  IQKIENLEAQTELRCLFLQVNLLHKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTL 200

Query: 868  DIASNRIKKIENVSHLTELQEFWMND---NLLESWSDLX*AQGAQSLETVYLERTPCRRT 1038
             +A N ++ ++++ HL E  +  + D   N L     L   +    L  + L   P  RT
Sbjct: 201  QMAHNHLETVQDIQHLKECLKLCVLDLSHNKLSDPEILSVLESMADLRVLNLMGNPVTRT 260



 Score = 65.5 bits (158), Expect = 5e-11
 Identities = 44/139 (31%), Positives = 79/139 (56%), Gaps = 6/139 (4%)
 Frame = +1

Query: 298 KIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDI 477
           +IE  +    ++ L L  N I+ IENLEA   LR L L  N + KIENLE L +L+ L++
Sbjct: 121 RIENLDEYTGLRCLWLECNGIQKIENLEAQTELRCLFLQVNLLHKIENLEPLQKLDALNL 180

Query: 478 SFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQ---LQMLELGSNRI---RAIEN 639
           S N +++IE +  L  L  L + +N +  ++++  L++   L +L+L  N++     +  
Sbjct: 181 SNNYIKTIENLSCLPVLNTLQMAHNHLETVQDIQHLKECLKLCVLDLSHNKLSDPEILSV 240

Query: 640 VDTLTNLESLFLGKNKITK 696
           ++++ +L  L L  N +T+
Sbjct: 241 LESMADLRVLNLMGNPVTR 259



 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 44/123 (35%), Positives = 67/123 (54%), Gaps = 7/123 (5%)
 Frame = +1

Query: 292 IGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEIL 471
           I KIE  E   +++ L L+ NL+  IENLE LQ L  L+L +N I+ IENL  L  L  L
Sbjct: 141 IQKIENLEAQTELRCLFLQVNLLHKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTL 200

Query: 472 DISFNLLRSIEGVDKLTRLKKLFLVNNKINKIEN------LSSLRQLQMLELGSNRI-RA 630
            ++ N L +++ +  L    KL +++   NK+ +      L S+  L++L L  N + R 
Sbjct: 201 QMAHNHLETVQDIQHLKECLKLCVLDLSHNKLSDPEILSVLESMADLRVLNLMGNPVTRT 260

Query: 631 IEN 639
           I N
Sbjct: 261 IPN 263


>ref|XP_003353284.1| PREDICTED: slit homolog 3 protein-like [Sus scrofa].
          Length = 303

 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 64/219 (29%), Positives = 118/219 (53%), Gaps = 10/219 (4%)
 Frame = +1

Query: 328 VKTLCLRQNLIKCIE--NLEALQSLRELDLYDNQIRKIE--NLEALTELEILDISFNLLR 495
           ++ L L  N I  +   + E L+ L  L+L +N I  +    L +L  L+ L +  N + 
Sbjct: 57  LEVLKLNDNSISVLHRSDFEGLKKLTILELKNNLISSLSPSTLSSLVSLQSLVLDGNSIE 116

Query: 496 SIEGVDKLTRLKKLFLVNNKINKIEN--LSSLRQLQMLELGSNRIRAIENVDTLTNLESL 669
           ++EG   L+ L  + + NNK++ +     +SL+ LQ L L SN +  I  ++   +L SL
Sbjct: 117 TVEGPLALSHLTHMSMENNKLHLLPAGFFTSLQSLQFLSLSSNFLTQIP-INLPKSLLSL 175

Query: 670 FLGKN--KITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLD 843
            + +N  K+   ++L  L NL+ L +  N L+  +G Q L NL  L LS N ++++  L 
Sbjct: 176 KMERNRLKVVSFEDLKHLENLSHLYLSENSLSSFDGAQLLANLTTLELSQNQLQMLP-LR 234

Query: 844 SNNKLTMLDIASNRIKKI--ENVSHLTELQEFWMNDNLL 954
              +L  LDI++N I+K+  ++   L +L+  ++++N++
Sbjct: 235 LPARLQKLDISNNLIQKVTAQDFQDLRDLKHLFLDNNIV 273



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 45/155 (29%), Positives = 79/155 (50%), Gaps = 8/155 (5%)
 Frame = +1

Query: 514 KLTRLKKLFLVNNKINKIEN--LSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNK 687
           ++  L+   L+ +    +EN    +L  L+ LEL  N++R I +     +LE L L  N 
Sbjct: 8   QMLALEDFILLASGTESVENDTFKTLSTLKTLELWKNKLRRIPSA-LPASLEVLKLNDNS 66

Query: 688 ITKLQNLD--ALTNLTVLSMQSNRLTKIEG--LQSLVNLRELYLSHNGIEVIEGLDSNNK 855
           I+ L   D   L  LT+L +++N ++ +    L SLV+L+ L L  N IE +EG  + + 
Sbjct: 67  ISVLHRSDFEGLKKLTILELKNNLISSLSPSTLSSLVSLQSLVLDGNSIETVEGPLALSH 126

Query: 856 LTMLDIASNRIKKIEN--VSHLTELQEFWMNDNLL 954
           LT + + +N++  +     + L  LQ   ++ N L
Sbjct: 127 LTHMSMENNKLHLLPAGFFTSLQSLQFLSLSSNFL 161


>ref|XP_003121288.1| PREDICTED: insulin-like growth factor-binding protein complex acid
           labile subunit-like [Sus scrofa].
          Length = 512

 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 64/219 (29%), Positives = 118/219 (53%), Gaps = 10/219 (4%)
 Frame = +1

Query: 328 VKTLCLRQNLIKCIE--NLEALQSLRELDLYDNQIRKIE--NLEALTELEILDISFNLLR 495
           ++ L L  N I  +   + E L+ L  L+L +N I  +    L +L  L+ L +  N + 
Sbjct: 118 LEVLKLNDNSISVLHRSDFEGLKKLTILELKNNLISSLSPSTLSSLVSLQSLVLDGNSIE 177

Query: 496 SIEGVDKLTRLKKLFLVNNKINKIEN--LSSLRQLQMLELGSNRIRAIENVDTLTNLESL 669
           ++EG   L+ L  + + NNK++ +     +SL+ LQ L L SN +  I  ++   +L SL
Sbjct: 178 TVEGPLALSHLTHMSMENNKLHLLPAGFFTSLQSLQFLSLSSNFLTQIP-INLPKSLLSL 236

Query: 670 FLGKN--KITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLD 843
            + +N  K+   ++L  L NL+ L +  N L+  +G Q L NL  L LS N ++++  L 
Sbjct: 237 KMERNRLKVVSFEDLKHLENLSHLYLSENSLSSFDGAQLLANLTTLELSQNQLQMLP-LR 295

Query: 844 SNNKLTMLDIASNRIKKI--ENVSHLTELQEFWMNDNLL 954
              +L  LDI++N I+K+  ++   L +L+  ++++N++
Sbjct: 296 LPARLQKLDISNNLIQKVTAQDFQDLRDLKHLFLDNNIV 334



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 42/137 (30%), Positives = 71/137 (51%), Gaps = 6/137 (4%)
 Frame = +1

Query: 562 KIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLD--ALTNLTVL 735
           K +   +L  L+ LEL  N++R I +     +LE L L  N I+ L   D   L  LT+L
Sbjct: 87  KNDTFKTLSTLKTLELWKNKLRRIPSA-LPASLEVLKLNDNSISVLHRSDFEGLKKLTIL 145

Query: 736 SMQSNRLTKIEG--LQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIEN-- 903
            +++N ++ +    L SLV+L+ L L  N IE +EG  + + LT + + +N++  +    
Sbjct: 146 ELKNNLISSLSPSTLSSLVSLQSLVLDGNSIETVEGPLALSHLTHMSMENNKLHLLPAGF 205

Query: 904 VSHLTELQEFWMNDNLL 954
            + L  LQ   ++ N L
Sbjct: 206 FTSLQSLQFLSLSSNFL 222


>ref|XP_001926121.1| PREDICTED: leucine-rich repeat-containing protein 67-like [Sus
           scrofa].
          Length = 230

 Score = 78.2 bits (191), Expect = 7e-15
 Identities = 58/193 (30%), Positives = 96/193 (49%), Gaps = 8/193 (4%)
 Frame = +1

Query: 235 METINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLY 414
           M  + LD  A++++L   +   I  +  L+K+  +      I  I+NL   ++L  L LY
Sbjct: 1   MVRLTLDLIAKNINLKSRKEETISQY--LKKITHINFSDKNIDAIDNLSLCKNLSVLYLY 58

Query: 415 DNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQL 594
           DN+I +I NL   T L  L +  N + S+E +  L +L+KL+L  N I  IE L  L  L
Sbjct: 59  DNRISQITNLNYATNLTHLYLQNNCISSMENLRSLKKLEKLYLGGNYIAVIEGLEGLEGL 118

Query: 595 QMLELGSNRIRAIENV--------DTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 750
           + L + S R+   E +            +L  L +  N I  +++L+ L NL  L+   N
Sbjct: 119 RELHVESQRLPPGEKLLFDPRTLHSLAKSLSILNISNNNIDDIRDLEILENLKQLTAVDN 178

Query: 751 RLTKIEGLQSLVN 789
           +L  ++ L+ L+N
Sbjct: 179 QLLHVKDLEFLLN 191



 Score = 75.1 bits (183), Expect = 6e-14
 Identities = 44/116 (37%), Positives = 68/116 (58%), Gaps = 1/116 (0%)
 Frame = +1

Query: 544 VNNKINKIENLSS-LRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALT 720
           +N K  K E +S  L+++  +      I AI+N+    NL  L+L  N+I+++ NL+  T
Sbjct: 13  INLKSRKEETISQYLKKITHINFSDKNIDAIDNLSLCKNLSVLYLYDNRISQITNLNYAT 72

Query: 721 NLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRI 888
           NLT L +Q+N ++ +E L+SL  L +LYL  N I VIEGL+    L  L + S R+
Sbjct: 73  NLTHLYLQNNCISSMENLRSLKKLEKLYLGGNYIAVIEGLEGLEGLRELHVESQRL 128



 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 54/160 (33%), Positives = 82/160 (51%), Gaps = 11/160 (6%)
 Frame = +1

Query: 526 LKKLFLVN---NKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITK 696
           LKK+  +N     I+ I+NLS  + L +L L  NRI  I N++  TNL  L+L  N I+ 
Sbjct: 27  LKKITHINFSDKNIDAIDNLSLCKNLSVLYLYDNRISQITNLNYATNLTHLYLQNNCISS 86

Query: 697 LQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGL--------DSNN 852
           ++NL +L  L  L +  N +  IEGL+ L  LREL++    +   E L            
Sbjct: 87  MENLRSLKKLEKLYLGGNYIAVIEGLEGLEGLRELHVESQRLPPGEKLLFDPRTLHSLAK 146

Query: 853 KLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            L++L+I++N I  I ++  L  L++    DN L    DL
Sbjct: 147 SLSILNISNNNIDDIRDLEILENLKQLTAVDNQLLHVKDL 186


>ref|XP_003355739.1| PREDICTED: leucine-rich repeat and IQ domain-containing protein 1
            [Sus scrofa].
          Length = 1596

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 66/236 (27%), Positives = 115/236 (48%), Gaps = 27/236 (11%)
 Frame = +1

Query: 328  VKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKI--ENLEALTELEILDISFNLLRSI 501
            ++ L L++  +  +  L   + L+ +D  +N+I  I  ENLE L  + +   + N L S 
Sbjct: 824  LQCLSLQRCGLTSLHGLNNCKKLKYIDAQENRIETISCENLEHLCAVVL---NKNQLTSF 880

Query: 502  EGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAI-ENVDTLTNLESLFLG 678
             G+D  T ++KL L +NKI +IE L+++ +   + L   R  AI   +++L NL+ L + 
Sbjct: 881  HGLDGCTNIQKLELSHNKITRIE-LTTIHRWLQIHLDLARCNAIIGGLESLKNLQQLIVD 939

Query: 679  KNKITKLQNLDALTNLTVLSMQSNRLTKIEG----------------------LQSLVNL 792
             N++   + L  +  +T L    N LT++EG                      L++ V L
Sbjct: 940  HNQLISTKGLCDIPTVTYLDCSYNHLTEVEGIENCGLLQILKLRGNYLSELPSLENHVLL 999

Query: 793  RELYLSHNGIEVIEGLDSN--NKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLL 954
            REL+L  N I  +E   S     L +L I+ N + KI  + H   L++  +++N L
Sbjct: 1000 RELHLDDNSISTMETFSSYWLPLLQILTISQNSLTKIIPLFHFVSLEKLDVSNNCL 1055



 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 51/194 (26%), Positives = 92/194 (47%), Gaps = 24/194 (12%)
 Frame = +1

Query: 463  EILDISFNLLR--SIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIE 636
            ++  ISF  L   S+  + + T L+ L L    +  +  L++ ++L+ ++   NRI  I 
Sbjct: 801  QVTTISFQDLPGCSLSTLAECTNLQCLSLQRCGLTSLHGLNNCKKLKYIDAQENRIETI- 859

Query: 637  NVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIE---------------- 768
            + + L +L ++ L KN++T    LD  TN+  L +  N++T+IE                
Sbjct: 860  SCENLEHLCAVVLNKNQLTSFHGLDGCTNIQKLELSHNKITRIELTTIHRWLQIHLDLAR 919

Query: 769  ------GLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQE 930
                  GL+SL NL++L + HN +   +GL     +T LD + N + ++E + +   LQ 
Sbjct: 920  CNAIIGGLESLKNLQQLIVDHNQLISTKGLCDIPTVTYLDCSYNHLTEVEGIENCGLLQI 979

Query: 931  FWMNDNLLESWSDL 972
              +  N L     L
Sbjct: 980  LKLRGNYLSELPSL 993



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 52/216 (24%), Positives = 100/216 (46%), Gaps = 24/216 (11%)
 Frame = +1

Query: 385  LQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINK 564
            LQ +  +   D     +  L   T L+ L +    L S+ G   L   KKL  ++ + N+
Sbjct: 799  LQQVTTISFQDLPGCSLSTLAECTNLQCLSLQRCGLTSLHG---LNNCKKLKYIDAQENR 855

Query: 565  IENLS--SLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQ------------ 702
            IE +S  +L  L  + L  N++ +   +D  TN++ L L  NKIT+++            
Sbjct: 856  IETISCENLEHLCAVVLNKNQLTSFHGLDGCTNIQKLELSHNKITRIELTTIHRWLQIHL 915

Query: 703  ----------NLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNN 852
                       L++L NL  L +  N+L   +GL  +  +  L  S+N +  +EG+++  
Sbjct: 916  DLARCNAIIGGLESLKNLQQLIVDHNQLISTKGLCDIPTVTYLDCSYNHLTEVEGIENCG 975

Query: 853  KLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
             L +L +  N + ++ ++ +   L+E  ++DN + +
Sbjct: 976  LLQILKLRGNYLSELPSLENHVLLRELHLDDNSIST 1011



 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 53/193 (27%), Positives = 100/193 (51%), Gaps = 9/193 (4%)
 Frame = +1

Query: 265  EDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKC---IENLEALQSLRELDLYDNQIRKI 435
            + ++L+H +I +IE   + R ++   +  +L +C   I  LE+L++L++L +  NQ+   
Sbjct: 890  QKLELSHNKITRIELTTIHRWLQ---IHLDLARCNAIIGGLESLKNLQQLIVDHNQLIST 946

Query: 436  ENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGS 615
            + L  +  +  LD S+N L  +EG++    L+ L L  N ++++ +L +   L+ L L  
Sbjct: 947  KGLCDIPTVTYLDCSYNHLTEVEGIENCGLLQILKLRGNYLSELPSLENHVLLRELHLDD 1006

Query: 616  NRIRAIENVDT--LTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLT----KIEGLQ 777
            N I  +E   +  L  L+ L + +N +TK+  L    +L  L + +N L+     I    
Sbjct: 1007 NSISTMETFSSYWLPLLQILTISQNSLTKIIPLFHFVSLEKLDVSNNCLSDLANTIRWFD 1066

Query: 778  SLVNLRELYLSHN 816
            +  +LREL L  N
Sbjct: 1067 ACFSLRELSLIGN 1079



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 53/215 (24%), Positives = 100/215 (46%), Gaps = 24/215 (11%)
 Frame = +1

Query: 244  INLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLR----------------QNLIKCIEN 375
            + ++++   V    +R G +  ++  ++V TLCL                   +  C   
Sbjct: 1315 VRMNQEKWTVAEAEFRDGSLFHYQKSKQVCTLCLHFRCSVALILISPFIPLAKVFSCFST 1374

Query: 376  --LEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVN 549
              LE+L++L++L +  NQ+   + L  +  +  LD S+N L  +EG++    L+ L L  
Sbjct: 1375 CGLESLKNLQQLIVDHNQLISTKGLCDIPTVTYLDCSYNHLTEVEGIENCGLLQILKLRG 1434

Query: 550  NKINKIENLSSLRQLQMLELGSNRIRAIENVDT--LTNLESLFLGKNKITKLQNLDALTN 723
            N ++++ +L +   L+ L L  N I  +E   +  L  L+ L + +N +TK+  L    +
Sbjct: 1435 NYLSELPSLENHVLLRELHLDDNSISTMETFSSYWLPLLQILTISQNSLTKIIPLFHFVS 1494

Query: 724  LTVLSMQSNRLT----KIEGLQSLVNLRELYLSHN 816
            L  L + +N L+     I    +  +LREL L  N
Sbjct: 1495 LEKLDVSNNCLSDLANTIRWFDACFSLRELSLIGN 1529


>ref|XP_003355547.1| PREDICTED: leucine-rich repeats and immunoglobulin-like domains
            protein 3-like [Sus scrofa].
          Length = 734

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 76/233 (32%), Positives = 121/233 (51%), Gaps = 17/233 (7%)
 Frame = +1

Query: 370  ENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEG--VDKLTR-LKKLF 540
            E+L   QSL  LDL  N I +++      +L+ L I+ N + S+E    D L   L  L 
Sbjct: 26   EHLRQFQSLETLDLSGNNISELKTALPPLQLKYLYINSNRVTSMEPGYFDNLANTLLVLK 85

Query: 541  LVNNKINKI-ENLSSLRQLQMLELGSNRIRAIENVDTLT-----NLESLFLGKNKITKLQ 702
            L  N+I  +   +  L QLQ LEL  N+I+   NVD LT      L+SL + +N +TKL 
Sbjct: 86   LNRNRITALPPKMFKLPQLQHLELNRNKIK---NVDGLTFQGLGALKSLKMQRNGVTKLM 142

Query: 703  N--LDALTNLTVLSMQSNRLTKIE--GLQSLVNLRELYLSHNGIEVI--EGLDSNNKLTM 864
            +     L+N+ +L +  N LT+I    L  L+ L+EL+LS N I  I  +  +   KL+ 
Sbjct: 143  DGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSE 202

Query: 865  LDIASNRIKKIENVSH--LTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLE 1017
            LD+  N + ++++ S   L+ L    + +N +   +D    +G  SL+T+ L+
Sbjct: 203  LDLTFNHLSRLDDSSFLGLSLLNTLHIGNNKVSYIADCA-FRGLSSLKTLDLK 254


  Database: RefSeq49_SP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 11,343,932
  Number of sequences in database:  24,897
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 24897
Number of Hits to DB: 20,137,816
Number of extensions: 485929
Number of successful extensions: 2429
Number of sequences better than 1.0e-05: 70
Number of HSP's gapped: 2262
Number of HSP's successfully gapped: 123
Length of query: 346
Length of database: 11,343,932
Length adjustment: 100
Effective length of query: 246
Effective length of database: 8,854,232
Effective search space: 2178141072
Effective search space used: 2178141072
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 34 (17.7 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007857
         (1040 letters)

Database: RefSeq49_MP.fasta 
           30,036 sequences; 15,617,559 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_075689.1| protein phosphatase 1 regulatory subunit 7 [Mus...   511   e-145
Alignment   gi|NP_001139518.1| leucine-rich repeat-containing protein 49 is...   103   2e-22
Alignment   gi|NP_663591.3| leucine-rich repeat-containing protein 49 isofo...   103   2e-22
Alignment   gi|NP_001139519.1| leucine-rich repeat-containing protein 49 is...   103   2e-22
Alignment   gi|NP_001136200.1| leucine-rich repeat-containing protein 9 iso...    93   3e-19
Alignment   gi|NP_084346.2| leucine-rich repeat-containing protein 9 isofor...    93   3e-19
Alignment   gi|NP_001136201.1| leucine-rich repeat-containing protein 9 iso...    93   3e-19
Alignment   gi|NP_796126.4| leucine-rich repeats and immunoglobulin-like do...    91   1e-18
Alignment   gi|NP_001157031.1| leucine-rich repeat and IQ domain-containing...    90   3e-18
Alignment   gi|NP_083162.1| leucine-rich repeat and guanylate kinase domain...    87   2e-17

>ref|NP_075689.1| protein phosphatase 1 regulatory subunit 7 [Mus musculus].
          Length = 361

 Score =  511 bits (1315), Expect = e-145
 Identities = 270/336 (80%), Positives = 291/336 (86%), Gaps = 1/336 (0%)
 Frame = +1

Query: 31   MAAERGTGQQQSQEMMEVDRRVXXXXXXXXXXXXXXXX-IVADLSEHSLKDXXXXXXXXX 207
            MAAERG GQQQSQEMMEVDRRV                 IVA+LSE SLKD         
Sbjct: 1    MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHGGGGIVANLSEQSLKDGVDRGAEDP 60

Query: 208  XXXXXXXVDMETINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEAL 387
                   VDMETINLDRDAEDVDL HYRIGKIEG EVL+KVK+LCLRQNLIKCIENLE L
Sbjct: 61   EEEHELAVDMETINLDRDAEDVDLTHYRIGKIEGLEVLKKVKSLCLRQNLIKCIENLEEL 120

Query: 388  QSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKI 567
            QSLRELDLYDNQI+KIENLEALTELE+LDISFN+LR+IEG+DKLT+LKKLFLVNNKINKI
Sbjct: 121  QSLRELDLYDNQIKKIENLEALTELEVLDISFNMLRNIEGIDKLTQLKKLFLVNNKINKI 180

Query: 568  ENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQS 747
            EN+S+L QLQMLELGSNRIRAIEN+DTLTNLESLFLGKNKITKLQNLDALTNLTVLS+QS
Sbjct: 181  ENISNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSVQS 240

Query: 748  NRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQ 927
            NRL KIEGLQSLVNLRELYLS+NGIEVIEGL++NNKLTMLDIASNRIKKIEN+SHLTELQ
Sbjct: 241  NRLAKIEGLQSLVNLRELYLSNNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQ 300

Query: 928  EFWMNDNLLESWSDLX*AQGAQSLETVYLERTPCRR 1035
            EFWMNDNLLESWSDL   +GA+SLETVYLER P ++
Sbjct: 301  EFWMNDNLLESWSDLDELKGARSLETVYLERNPLQK 336



 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 42/111 (37%), Positives = 61/111 (54%)
 Frame = +1

Query: 289 RIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEI 468
           R+ KIEG + L  ++ L L  N I+ IE LE    L  LD+  N+I+KIEN+  LTEL+ 
Sbjct: 242 RLAKIEGLQSLVNLRELYLSNNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQE 301

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNR 621
             ++ NLL S   +D+L   + L  V  + N ++     R+  ML L S R
Sbjct: 302 FWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVR 352


>ref|NP_001139518.1| leucine-rich repeat-containing protein 49 isoform 1 [Mus musculus].
          Length = 686

 Score =  103 bits (258), Expect = 2e-22
 Identities = 67/192 (34%), Positives = 107/192 (55%), Gaps = 5/192 (2%)
 Frame = +1

Query: 460  LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIEN 639
            L +L+   N +  I+ +  L RL  L L +N+I +I  LS+L+ L++L LG NRI+ I N
Sbjct: 114  LRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISN 173

Query: 640  VDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNG 819
            ++ L NL+ L L  N+ITK++N++ L +L VL++  N L+ ++ L  L +L EL L HN 
Sbjct: 174  LENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQ 233

Query: 820  IEVIEGLDSNNKLTMLDIASNRIKKIENVSHL---TELQEFWMNDNLL--ESWSDLX*AQ 984
            I  +  +D+   L  L ++ N I   E+VS L   T L +   + N +  ESW      Q
Sbjct: 234  ITFVRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQESWYKHTVLQ 293

Query: 985  GAQSLETVYLER 1020
                L  + ++R
Sbjct: 294  NMMQLRQLDMKR 305



 Score =  101 bits (252), Expect = 8e-22
 Identities = 58/173 (33%), Positives = 100/173 (57%)
 Frame = +1

Query: 508  VDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNK 687
            +D    L+ L   +N I +I+N+S+L++L  L+L  N+I  I  + TL +L  L LGKN+
Sbjct: 108  IDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNR 167

Query: 688  ITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTML 867
            I K+ NL+ L NL VL +  N++TKIE +  L +LR L L+ N +  ++ L+  + LT L
Sbjct: 168  IKKISNLENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTEL 227

Query: 868  DIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERTP 1026
            ++  N+I  + +V +L  LQ  +++ N + S+  +     + SL  +  +  P
Sbjct: 228  NLRHNQITFVRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNP 280



 Score =  100 bits (248), Expect = 2e-21
 Identities = 68/212 (32%), Positives = 110/212 (51%), Gaps = 3/212 (1%)
 Frame = +1

Query: 346 RQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTR 525
           RQ L  C   ++  + LR L+   N I +I+N+  L  L  LD+  N +  I G+  L  
Sbjct: 99  RQKLTVC-PIIDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKS 157

Query: 526 LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
           L+ L L  N+I KI NL +L+ L +L+L  N+I  IENV+ L +L  L L +N ++ + N
Sbjct: 158 LRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDN 217

Query: 706 LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGI---EVIEGLDSNNKLTMLDIA 876
           L+ L +LT L+++ N++T +  + +L  L+ L+LS N I   E +  L  +  L+ +   
Sbjct: 218 LNGLDSLTELNLRHNQITFVRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFD 277

Query: 877 SNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            N I            QE W    +L++   L
Sbjct: 278 GNPI-----------AQESWYKHTVLQNMMQL 298



 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 64/185 (34%), Positives = 102/185 (55%), Gaps = 8/185 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           ++  H  I +I+    L+++  L L  N I+ I  L  L+SLR L L  N+I+KI NLE 
Sbjct: 117 LNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLEN 176

Query: 451 LTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRA 630
           L  L++LD+  N +  IE V+ L  L+ L L  N ++ ++NL+ L  L  L L  N+I  
Sbjct: 177 LKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQITF 236

Query: 631 IENVDTLTNLESLFLGKNKITKLQNLDAL---TNLTVLSMQSNRLT-----KIEGLQSLV 786
           + +VD L  L+ LFL  N IT  +++  L   T+L+ ++   N +      K   LQ+++
Sbjct: 237 VRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQESWYKHTVLQNMM 296

Query: 787 NLREL 801
            LR+L
Sbjct: 297 QLRQL 301



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 43/124 (34%), Positives = 67/124 (54%)
 Frame = +1

Query: 601 LELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQS 780
           L L   ++     +D   +L  L    N IT++QN+  L  L  L +  N++ +I GL +
Sbjct: 95  LTLERQKLTVCPIIDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLST 154

Query: 781 LVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
           L +LR L L  N I+ I  L++   L +LD+  N+I KIENV+HL +L+   +  NLL  
Sbjct: 155 LKSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSH 214

Query: 961 WSDL 972
             +L
Sbjct: 215 VDNL 218



 Score = 65.1 bits (157), Expect = 9e-11
 Identities = 48/154 (31%), Positives = 75/154 (48%)
 Frame = +1

Query: 487 LLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLES 666
           L RS E  +K     +L L   K+     +     L++L    N I  I+N+  L  L  
Sbjct: 81  LQRSSE--EKTLYSDRLTLERQKLTVCPIIDGEEHLRLLNFQHNFITRIQNISNLQRLIF 138

Query: 667 LFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDS 846
           L L  N+I ++  L  L +L VL +  NR+ KI  L++L NL  L L  N I  IE ++ 
Sbjct: 139 LDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENVNH 198

Query: 847 NNKLTMLDIASNRIKKIENVSHLTELQEFWMNDN 948
              L +L++A N +  ++N++ L  L E  +  N
Sbjct: 199 LCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHN 232



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 42/126 (33%), Positives = 67/126 (53%), Gaps = 11/126 (8%)
 Frame = +1

Query: 256 RDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKI 435
           ++ + +DL+  +I KIE    L  ++ L L +NL+  ++NL  L SL EL+L  NQI  +
Sbjct: 178 KNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQITFV 237

Query: 436 ENLEALTELEILDISFNLLRSIEGVDKL---TRLKKLFLVNNKINK--------IENLSS 582
            +++ L  L+ L +SFN + S E V  L   T L  +    N I +        ++N+  
Sbjct: 238 RDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQESWYKHTVLQNMMQ 297

Query: 583 LRQLQM 600
           LRQL M
Sbjct: 298 LRQLDM 303


>ref|NP_663591.3| leucine-rich repeat-containing protein 49 isoform 2 [Mus musculus].
          Length = 752

 Score =  103 bits (258), Expect = 2e-22
 Identities = 67/192 (34%), Positives = 107/192 (55%), Gaps = 5/192 (2%)
 Frame = +1

Query: 460  LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIEN 639
            L +L+   N +  I+ +  L RL  L L +N+I +I  LS+L+ L++L LG NRI+ I N
Sbjct: 180  LRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISN 239

Query: 640  VDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNG 819
            ++ L NL+ L L  N+ITK++N++ L +L VL++  N L+ ++ L  L +L EL L HN 
Sbjct: 240  LENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQ 299

Query: 820  IEVIEGLDSNNKLTMLDIASNRIKKIENVSHL---TELQEFWMNDNLL--ESWSDLX*AQ 984
            I  +  +D+   L  L ++ N I   E+VS L   T L +   + N +  ESW      Q
Sbjct: 300  ITFVRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQESWYKHTVLQ 359

Query: 985  GAQSLETVYLER 1020
                L  + ++R
Sbjct: 360  NMMQLRQLDMKR 371



 Score =  101 bits (252), Expect = 8e-22
 Identities = 58/173 (33%), Positives = 100/173 (57%)
 Frame = +1

Query: 508  VDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNK 687
            +D    L+ L   +N I +I+N+S+L++L  L+L  N+I  I  + TL +L  L LGKN+
Sbjct: 174  IDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNR 233

Query: 688  ITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTML 867
            I K+ NL+ L NL VL +  N++TKIE +  L +LR L L+ N +  ++ L+  + LT L
Sbjct: 234  IKKISNLENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTEL 293

Query: 868  DIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERTP 1026
            ++  N+I  + +V +L  LQ  +++ N + S+  +     + SL  +  +  P
Sbjct: 294  NLRHNQITFVRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNP 346



 Score =  100 bits (248), Expect = 2e-21
 Identities = 68/212 (32%), Positives = 110/212 (51%), Gaps = 3/212 (1%)
 Frame = +1

Query: 346 RQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTR 525
           RQ L  C   ++  + LR L+   N I +I+N+  L  L  LD+  N +  I G+  L  
Sbjct: 165 RQKLTVC-PIIDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKS 223

Query: 526 LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
           L+ L L  N+I KI NL +L+ L +L+L  N+I  IENV+ L +L  L L +N ++ + N
Sbjct: 224 LRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDN 283

Query: 706 LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGI---EVIEGLDSNNKLTMLDIA 876
           L+ L +LT L+++ N++T +  + +L  L+ L+LS N I   E +  L  +  L+ +   
Sbjct: 284 LNGLDSLTELNLRHNQITFVRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFD 343

Query: 877 SNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            N I            QE W    +L++   L
Sbjct: 344 GNPI-----------AQESWYKHTVLQNMMQL 364



 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 64/185 (34%), Positives = 102/185 (55%), Gaps = 8/185 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           ++  H  I +I+    L+++  L L  N I+ I  L  L+SLR L L  N+I+KI NLE 
Sbjct: 183 LNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLEN 242

Query: 451 LTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRA 630
           L  L++LD+  N +  IE V+ L  L+ L L  N ++ ++NL+ L  L  L L  N+I  
Sbjct: 243 LKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQITF 302

Query: 631 IENVDTLTNLESLFLGKNKITKLQNLDAL---TNLTVLSMQSNRLT-----KIEGLQSLV 786
           + +VD L  L+ LFL  N IT  +++  L   T+L+ ++   N +      K   LQ+++
Sbjct: 303 VRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQESWYKHTVLQNMM 362

Query: 787 NLREL 801
            LR+L
Sbjct: 363 QLRQL 367



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 43/124 (34%), Positives = 67/124 (54%)
 Frame = +1

Query: 601 LELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQS 780
           L L   ++     +D   +L  L    N IT++QN+  L  L  L +  N++ +I GL +
Sbjct: 161 LTLERQKLTVCPIIDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLST 220

Query: 781 LVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
           L +LR L L  N I+ I  L++   L +LD+  N+I KIENV+HL +L+   +  NLL  
Sbjct: 221 LKSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSH 280

Query: 961 WSDL 972
             +L
Sbjct: 281 VDNL 284



 Score = 65.1 bits (157), Expect = 9e-11
 Identities = 48/154 (31%), Positives = 75/154 (48%)
 Frame = +1

Query: 487 LLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLES 666
           L RS E  +K     +L L   K+     +     L++L    N I  I+N+  L  L  
Sbjct: 147 LQRSSE--EKTLYSDRLTLERQKLTVCPIIDGEEHLRLLNFQHNFITRIQNISNLQRLIF 204

Query: 667 LFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDS 846
           L L  N+I ++  L  L +L VL +  NR+ KI  L++L NL  L L  N I  IE ++ 
Sbjct: 205 LDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENVNH 264

Query: 847 NNKLTMLDIASNRIKKIENVSHLTELQEFWMNDN 948
              L +L++A N +  ++N++ L  L E  +  N
Sbjct: 265 LCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHN 298



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 42/126 (33%), Positives = 67/126 (53%), Gaps = 11/126 (8%)
 Frame = +1

Query: 256 RDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKI 435
           ++ + +DL+  +I KIE    L  ++ L L +NL+  ++NL  L SL EL+L  NQI  +
Sbjct: 244 KNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQITFV 303

Query: 436 ENLEALTELEILDISFNLLRSIEGVDKL---TRLKKLFLVNNKINK--------IENLSS 582
            +++ L  L+ L +SFN + S E V  L   T L  +    N I +        ++N+  
Sbjct: 304 RDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQESWYKHTVLQNMMQ 363

Query: 583 LRQLQM 600
           LRQL M
Sbjct: 364 LRQLDM 369


>ref|NP_001139519.1| leucine-rich repeat-containing protein 49 isoform 3 [Mus musculus].
          Length = 746

 Score =  103 bits (258), Expect = 2e-22
 Identities = 67/192 (34%), Positives = 107/192 (55%), Gaps = 5/192 (2%)
 Frame = +1

Query: 460  LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIEN 639
            L +L+   N +  I+ +  L RL  L L +N+I +I  LS+L+ L++L LG NRI+ I N
Sbjct: 174  LRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISN 233

Query: 640  VDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNG 819
            ++ L NL+ L L  N+ITK++N++ L +L VL++  N L+ ++ L  L +L EL L HN 
Sbjct: 234  LENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQ 293

Query: 820  IEVIEGLDSNNKLTMLDIASNRIKKIENVSHL---TELQEFWMNDNLL--ESWSDLX*AQ 984
            I  +  +D+   L  L ++ N I   E+VS L   T L +   + N +  ESW      Q
Sbjct: 294  ITFVRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQESWYKHTVLQ 353

Query: 985  GAQSLETVYLER 1020
                L  + ++R
Sbjct: 354  NMMQLRQLDMKR 365



 Score =  101 bits (252), Expect = 8e-22
 Identities = 58/173 (33%), Positives = 100/173 (57%)
 Frame = +1

Query: 508  VDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNK 687
            +D    L+ L   +N I +I+N+S+L++L  L+L  N+I  I  + TL +L  L LGKN+
Sbjct: 168  IDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNR 227

Query: 688  ITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTML 867
            I K+ NL+ L NL VL +  N++TKIE +  L +LR L L+ N +  ++ L+  + LT L
Sbjct: 228  IKKISNLENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTEL 287

Query: 868  DIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERTP 1026
            ++  N+I  + +V +L  LQ  +++ N + S+  +     + SL  +  +  P
Sbjct: 288  NLRHNQITFVRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNP 340



 Score =  100 bits (248), Expect = 2e-21
 Identities = 68/212 (32%), Positives = 110/212 (51%), Gaps = 3/212 (1%)
 Frame = +1

Query: 346 RQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTR 525
           RQ L  C   ++  + LR L+   N I +I+N+  L  L  LD+  N +  I G+  L  
Sbjct: 159 RQKLTVC-PIIDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKS 217

Query: 526 LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
           L+ L L  N+I KI NL +L+ L +L+L  N+I  IENV+ L +L  L L +N ++ + N
Sbjct: 218 LRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDN 277

Query: 706 LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGI---EVIEGLDSNNKLTMLDIA 876
           L+ L +LT L+++ N++T +  + +L  L+ L+LS N I   E +  L  +  L+ +   
Sbjct: 278 LNGLDSLTELNLRHNQITFVRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFD 337

Query: 877 SNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            N I            QE W    +L++   L
Sbjct: 338 GNPI-----------AQESWYKHTVLQNMMQL 358



 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 64/185 (34%), Positives = 102/185 (55%), Gaps = 8/185 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           ++  H  I +I+    L+++  L L  N I+ I  L  L+SLR L L  N+I+KI NLE 
Sbjct: 177 LNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLEN 236

Query: 451 LTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRA 630
           L  L++LD+  N +  IE V+ L  L+ L L  N ++ ++NL+ L  L  L L  N+I  
Sbjct: 237 LKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQITF 296

Query: 631 IENVDTLTNLESLFLGKNKITKLQNLDAL---TNLTVLSMQSNRLT-----KIEGLQSLV 786
           + +VD L  L+ LFL  N IT  +++  L   T+L+ ++   N +      K   LQ+++
Sbjct: 297 VRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQESWYKHTVLQNMM 356

Query: 787 NLREL 801
            LR+L
Sbjct: 357 QLRQL 361



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 43/124 (34%), Positives = 67/124 (54%)
 Frame = +1

Query: 601 LELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQS 780
           L L   ++     +D   +L  L    N IT++QN+  L  L  L +  N++ +I GL +
Sbjct: 155 LTLERQKLTVCPIIDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLST 214

Query: 781 LVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
           L +LR L L  N I+ I  L++   L +LD+  N+I KIENV+HL +L+   +  NLL  
Sbjct: 215 LKSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSH 274

Query: 961 WSDL 972
             +L
Sbjct: 275 VDNL 278



 Score = 65.1 bits (157), Expect = 9e-11
 Identities = 48/154 (31%), Positives = 75/154 (48%)
 Frame = +1

Query: 487 LLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLES 666
           L RS E  +K     +L L   K+     +     L++L    N I  I+N+  L  L  
Sbjct: 141 LQRSSE--EKTLYSDRLTLERQKLTVCPIIDGEEHLRLLNFQHNFITRIQNISNLQRLIF 198

Query: 667 LFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDS 846
           L L  N+I ++  L  L +L VL +  NR+ KI  L++L NL  L L  N I  IE ++ 
Sbjct: 199 LDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENVNH 258

Query: 847 NNKLTMLDIASNRIKKIENVSHLTELQEFWMNDN 948
              L +L++A N +  ++N++ L  L E  +  N
Sbjct: 259 LCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHN 292



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 42/126 (33%), Positives = 67/126 (53%), Gaps = 11/126 (8%)
 Frame = +1

Query: 256 RDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKI 435
           ++ + +DL+  +I KIE    L  ++ L L +NL+  ++NL  L SL EL+L  NQI  +
Sbjct: 238 KNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQITFV 297

Query: 436 ENLEALTELEILDISFNLLRSIEGVDKL---TRLKKLFLVNNKINK--------IENLSS 582
            +++ L  L+ L +SFN + S E V  L   T L  +    N I +        ++N+  
Sbjct: 298 RDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQESWYKHTVLQNMMQ 357

Query: 583 LRQLQM 600
           LRQL M
Sbjct: 358 LRQLDM 363


>ref|NP_001136200.1| leucine-rich repeat-containing protein 9 isoform 1 [Mus musculus].
          Length = 1456

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 66/196 (33%), Positives = 106/196 (54%), Gaps = 4/196 (2%)
 Frame = +1

Query: 370 ENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVN 549
           ENL   + ++EL L +    +I   E  ++   L++ F+    I G+     L  L +V 
Sbjct: 5   ENLNRGEIIKELCLCNGLTYEIVGQEG-SDTSKLEMFFSGYPRIVGLSLFHNLSSLTIVA 63

Query: 550 NKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLT 729
             I +I  L +  QL+ L +    I  IE +    NLE L+L  NKI+K++NL+ L  L 
Sbjct: 64  QDIREISGLETCLQLKELWIAECCIEKIEGLQGCRNLEKLYLYYNKISKIENLEKLIKLE 123

Query: 730 VLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVI-EGLDSNNKLTMLDIASNRI---KKI 897
           VL +  N +  IEGLQ+L NL++L L+ N +  I   LD N +L  L+++ N+I   K +
Sbjct: 124 VLWLNHNMIKNIEGLQTLKNLKDLNLAGNLVSSIGRCLDPNEQLEKLNLSGNQITSFKDL 183

Query: 898 ENVSHLTELQEFWMND 945
            N++ LT L++  +ND
Sbjct: 184 TNLTKLTRLKDLCLND 199



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 61/208 (29%), Positives = 103/208 (49%), Gaps = 17/208 (8%)
 Frame = +1

Query: 367 IENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLV 546
           I  L    +L  L +    IR+I  LE   +L+ L I+   +  IEG+     L+KL+L 
Sbjct: 47  IVGLSLFHNLSSLTIVAQDIREISGLETCLQLKELWIAECCIEKIEGLQGCRNLEKLYLY 106

Query: 547 NNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKL-QNLDALTN 723
            NKI+KIENL  L +L++L L  N I+ IE + TL NL+ L L  N ++ + + LD    
Sbjct: 107 YNKISKIENLEKLIKLEVLWLNHNMIKNIEGLQTLKNLKDLNLAGNLVSSIGRCLDPNEQ 166

Query: 724 LTVLSMQSNRLTKIEGLQSLVNLREL----------------YLSHNGIEVIEGLDSNNK 855
           L  L++  N++T  + L +L  L  L                 L +    V+  L S  +
Sbjct: 167 LEKLNLSGNQITSFKDLTNLTKLTRLKDLCLNDPQYKSNPVCQLCNYSTHVLYHLPSLQR 226

Query: 856 LTMLDIASNRIKKIENVSHLTELQEFWM 939
           L   D+++ +IK++ + + + ++  + M
Sbjct: 227 LDTFDVSAKQIKELADSTAMKKIMYYNM 254



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 48/127 (37%), Positives = 76/127 (59%), Gaps = 1/127 (0%)
 Frame = +1

Query: 292 IGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEIL 471
           I +I G E   ++K L + +  I+ IE L+  ++L +L LY N+I KIENLE L +LE+L
Sbjct: 66  IREISGLETCLQLKELWIAECCIEKIEGLQGCRNLEKLYLYYNKISKIENLEKLIKLEVL 125

Query: 472 DISFNLLRSIEGVDKLTRLKKLFLVNNKINKIEN-LSSLRQLQMLELGSNRIRAIENVDT 648
            ++ N++++IEG+  L  LK L L  N ++ I   L    QL+ L L  N+I + +++  
Sbjct: 126 WLNHNMIKNIEGLQTLKNLKDLNLAGNLVSSIGRCLDPNEQLEKLNLSGNQITSFKDLTN 185

Query: 649 LTNLESL 669
           LT L  L
Sbjct: 186 LTKLTRL 192



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 52/150 (34%), Positives = 77/150 (51%), Gaps = 5/150 (3%)
 Frame = +1

Query: 454  TELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAI 633
            +++  L++    L  I  ++KL  LK     NN ++K+E L S   L+ L L  N I  I
Sbjct: 877  SKITALNLDGQHLFEITNLEKLENLKWASFSNNNLSKMEGLESCVNLEELTLDGNCISKI 936

Query: 634  ENVDTLTNLESLFLGKNKITKLQN--LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYL 807
            E +  LT L  L +  N +T L+    D L +L  LS+++NR+T +  LQ    L ELY+
Sbjct: 937  EGITRLTKLSRLSMNNNLLTGLEKHTFDNLLHLHSLSLENNRITSLSALQKTFTLIELYI 996

Query: 808  SHNGIEV---IEGLDSNNKLTMLDIASNRI 888
            S+N I V   I  L     L +LD+  N I
Sbjct: 997  SNNYIAVNQEIYNLKGLCNLVILDMYGNII 1026



 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 74/255 (29%), Positives = 117/255 (45%), Gaps = 19/255 (7%)
 Frame = +1

Query: 265  EDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCI-ENLEAL----QSLRELDLYDNQIR 429
            E +D +H  +  +EGF  L K+K L L  N +K   E +  L     SL  LD+  N  +
Sbjct: 731  EYLDASHNHVITLEGFRGLMKLKHLDLSWNQLKKTGEEINVLCKHTTSLLTLDIQHNPWQ 790

Query: 430  K--------IENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSL 585
            K        I  L+ LT L+ L IS    R+       T++ +L L+ +  +K E    L
Sbjct: 791  KPATLRLSVIGRLKTLTHLDGLVISEEETRAALKFISGTKITQLTLLQHSSSKEERPRML 850

Query: 586  RQLQMLELGSNRIRAIENVDTLTN----LESLFLGKNKITKLQNLDALTNLTVLSMQSNR 753
                  ++ +   +   +     N    + +L L    + ++ NL+ L NL   S  +N 
Sbjct: 851  STWPSAKILTQISKLGPHFHLTGNWYSKITALNLDGQHLFEITNLEKLENLKWASFSNNN 910

Query: 754  LTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIE--NVSHLTELQ 927
            L+K+EGL+S VNL EL L  N I  IEG+    KL+ L + +N +  +E     +L  L 
Sbjct: 911  LSKMEGLESCVNLEELTLDGNCISKIEGITRLTKLSRLSMNNNLLTGLEKHTFDNLLHLH 970

Query: 928  EFWMNDNLLESWSDL 972
               + +N + S S L
Sbjct: 971  SLSLENNRITSLSAL 985



 Score = 71.6 bits (174), Expect = 9e-13
 Identities = 67/281 (23%), Positives = 122/281 (43%), Gaps = 39/281 (13%)
 Frame = +1

Query: 229  VDMETINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELD 408
            + +   N+     +++L+   + K+     L  ++ L +  N   C++++  L +L  LD
Sbjct: 675  ISLAKTNIYSHIVNLNLHGNSLSKLRDLAKLTGLRKLNISFNEFTCLDDVYHLYNLEYLD 734

Query: 409  LYDNQIRKIENLEALTELEILDISFNLLRSI-EGVDKL----TRLKKLFLVNN------- 552
               N +  +E    L +L+ LD+S+N L+   E ++ L    T L  L + +N       
Sbjct: 735  ASHNHVITLEGFRGLMKLKHLDLSWNQLKKTGEEINVLCKHTTSLLTLDIQHNPWQKPAT 794

Query: 553  -KINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDAL---- 717
             +++ I  L +L  L  L +     RA     + T +  L L ++  +K +    L    
Sbjct: 795  LRLSVIGRLKTLTHLDGLVISEEETRAALKFISGTKITQLTLLQHSSSKEERPRMLSTWP 854

Query: 718  ----------------------TNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVI 831
                                  + +T L++    L +I  L+ L NL+    S+N +  +
Sbjct: 855  SAKILTQISKLGPHFHLTGNWYSKITALNLDGQHLFEITNLEKLENLKWASFSNNNLSKM 914

Query: 832  EGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLL 954
            EGL+S   L  L +  N I KIE ++ LT+L    MN+NLL
Sbjct: 915  EGLESCVNLEELTLDGNCISKIEGITRLTKLSRLSMNNNLL 955



 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 76/296 (25%), Positives = 125/296 (42%), Gaps = 48/296 (16%)
 Frame = +1

Query: 229  VDMETINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCI------------- 369
            VD+  ++  R+  +V+L +  +    G   L  VK LCL  N I+ I             
Sbjct: 1098 VDLIPVDHFRNVSNVNLQNNNLTSFSGLIYLPNVKVLCLNYNHIESIMPRLKPQTHLSSR 1157

Query: 370  ---------------------------ENLEAL-QSLRELDLYDNQIRKIENLEA--LTE 459
                                       ENL  + QSL  L L  N I  +  L+   L  
Sbjct: 1158 QLLYQKVPSSGYGQQGTSKLNRDSVGSENLPPIMQSLEVLHLGYNGICNLVQLQLNRLRN 1217

Query: 460  LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIEN--LSSLRQLQMLELGSNRIRAI 633
            L+ L +  N +  +EG+D L  L++L + +N+I    +   S    L ML L  NR+R +
Sbjct: 1218 LKFLFLQGNEISQVEGLDNLIVLQELVVDHNRIRAFNDTAFSKPSSLLMLHLEENRLREL 1277

Query: 634  ENVDTLTNLESLFLGKNK---ITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELY 804
              + +L  LE LFLG NK   IT+L+ LD + +L  L++  N + +      +V+   L 
Sbjct: 1278 SKLQSLVKLEKLFLGYNKIQDITELEKLDVIPSLRELTVYGNPICR-----KMVHRHVLI 1332

Query: 805  LSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
                 +++++G+  N        + +R K   + S L   +   + +NL  S S L
Sbjct: 1333 FRLPNLQMLDGIPIN--------SDDRAKAEFHFSELQAKKSSIIQNNLPTSKSSL 1380



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 40/125 (32%), Positives = 70/125 (56%)
 Frame = +1

Query: 634  ENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSH 813
            E  DT + LE  F G  +I  L     L++LT+++     + +I GL++ + L+EL+++ 
Sbjct: 30   EGSDT-SKLEMFFSGYPRIVGLSLFHNLSSLTIVAQD---IREISGLETCLQLKELWIAE 85

Query: 814  NGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQ 993
              IE IEGL     L  L +  N+I KIEN+  L +L+  W+N N++++       +G Q
Sbjct: 86   CCIEKIEGLQGCRNLEKLYLYYNKISKIENLEKLIKLEVLWLNHNMIKN------IEGLQ 139

Query: 994  SLETV 1008
            +L+ +
Sbjct: 140  TLKNL 144



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 49/155 (31%), Positives = 75/155 (48%), Gaps = 2/155 (1%)
 Frame = +1

Query: 502 EGVDKLTRLKKLFLVNNKINKI--ENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFL 675
           E +++   +K+L L N    +I  +  S   +L+M   G  RI  +       NL SL +
Sbjct: 5   ENLNRGEIIKELCLCNGLTYEIVGQEGSDTSKLEMFFSGYPRIVGLS---LFHNLSSLTI 61

Query: 676 GKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNK 855
               I ++  L+    L  L +    + KIEGLQ   NL +LYL +N I  IE L+   K
Sbjct: 62  VAQDIREISGLETCLQLKELWIAECCIEKIEGLQGCRNLEKLYLYYNKISKIENLEKLIK 121

Query: 856 LTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
           L +L +  N IK IE +  L  L++  +  NL+ S
Sbjct: 122 LEVLWLNHNMIKNIEGLQTLKNLKDLNLAGNLVSS 156



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 45/143 (31%), Positives = 77/143 (53%), Gaps = 17/143 (11%)
 Frame = +1

Query: 256 RDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKI 435
           R+ E + L + +I KIE  E L K++ L L  N+IK IE L+ L++L++L+L  N +  I
Sbjct: 98  RNLEKLYLYYNKISKIENLEKLIKLEVLWLNHNMIKNIEGLQTLKNLKDLNLAGNLVSSI 157

Query: 436 EN-LEALTELEILDISFNLLRS---IEGVDKLTRLKKLF-------------LVNNKINK 564
              L+   +LE L++S N + S   +  + KLTRLK L              L N   + 
Sbjct: 158 GRCLDPNEQLEKLNLSGNQITSFKDLTNLTKLTRLKDLCLNDPQYKSNPVCQLCNYSTHV 217

Query: 565 IENLSSLRQLQMLELGSNRIRAI 633
           + +L SL++L   ++ + +I+ +
Sbjct: 218 LYHLPSLQRLDTFDVSAKQIKEL 240



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 87/363 (23%), Positives = 147/363 (40%), Gaps = 97/363 (26%)
 Frame = +1

Query: 235  METINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIE-------------- 372
            ME +    + E++ L+   I KIEG   L K+  L +  NL+  +E              
Sbjct: 914  MEGLESCVNLEELTLDGNCISKIEGITRLTKLSRLSMNNNLLTGLEKHTFDNLLHLHSLS 973

Query: 373  -------NLEALQ---SLRELDLYDNQI---RKIENLEALTELEILDISFNL-------- 489
                   +L ALQ   +L EL + +N I   ++I NL+ L  L ILD+  N+        
Sbjct: 974  LENNRITSLSALQKTFTLIELYISNNYIAVNQEIYNLKGLCNLVILDMYGNIIIWNQENY 1033

Query: 490  ----------LRSIEGV----DKLTRLKKLF---LVNNKINKIENLSSLRQLQMLELGSN 618
                      L++++GV     +    K LF   L ++ I + +  S+  Q+Q L   S+
Sbjct: 1034 RFFVIFHLPELKALDGVSIETSETETAKDLFGGRLTSDMIAERQGHSNFIQMQELNWTSS 1093

Query: 619  RIRAIE--NVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKI--------- 765
             IR ++   VD   N+ ++ L  N +T    L  L N+ VL +  N +  I         
Sbjct: 1094 AIRTVDLIPVDHFRNVSNVNLQNNNLTSFSGLIYLPNVKVLCLNYNHIESIMPRLKPQTH 1153

Query: 766  -------------------------------EGLQSLV-NLRELYLSHNGIEVIEGLDSN 849
                                           E L  ++ +L  L+L +NGI  +  L  N
Sbjct: 1154 LSSRQLLYQKVPSSGYGQQGTSKLNRDSVGSENLPPIMQSLEVLHLGYNGICNLVQLQLN 1213

Query: 850  --NKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERT 1023
                L  L +  N I ++E + +L  LQE  ++ N + +++D   ++   SL  ++LE  
Sbjct: 1214 RLRNLKFLFLQGNEISQVEGLDNLIVLQELVVDHNRIRAFNDTAFSK-PSSLLMLHLEEN 1272

Query: 1024 PCR 1032
              R
Sbjct: 1273 RLR 1275



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 30/100 (30%), Positives = 55/100 (55%)
 Frame = +1

Query: 595 QMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGL 774
           +++ L    I ++   +  +++ +L L  N ++KL++L  LT L  L++  N  T ++ +
Sbjct: 665 KLISLDEKTIISLAKTNIYSHIVNLNLHGNSLSKLRDLAKLTGLRKLNISFNEFTCLDDV 724

Query: 775 QSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKK 894
             L NL  L  SHN +  +EG     KL  LD++ N++KK
Sbjct: 725 YHLYNLEYLDASHNHVITLEGFRGLMKLKHLDLSWNQLKK 764


>ref|NP_084346.2| leucine-rich repeat-containing protein 9 isoform 2 [Mus musculus].
          Length = 1155

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 66/196 (33%), Positives = 106/196 (54%), Gaps = 4/196 (2%)
 Frame = +1

Query: 370 ENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVN 549
           ENL   + ++EL L +    +I   E  ++   L++ F+    I G+     L  L +V 
Sbjct: 5   ENLNRGEIIKELCLCNGLTYEIVGQEG-SDTSKLEMFFSGYPRIVGLSLFHNLSSLTIVA 63

Query: 550 NKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLT 729
             I +I  L +  QL+ L +    I  IE +    NLE L+L  NKI+K++NL+ L  L 
Sbjct: 64  QDIREISGLETCLQLKELWIAECCIEKIEGLQGCRNLEKLYLYYNKISKIENLEKLIKLE 123

Query: 730 VLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVI-EGLDSNNKLTMLDIASNRI---KKI 897
           VL +  N +  IEGLQ+L NL++L L+ N +  I   LD N +L  L+++ N+I   K +
Sbjct: 124 VLWLNHNMIKNIEGLQTLKNLKDLNLAGNLVSSIGRCLDPNEQLEKLNLSGNQITSFKDL 183

Query: 898 ENVSHLTELQEFWMND 945
            N++ LT L++  +ND
Sbjct: 184 TNLTKLTRLKDLCLND 199



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 61/208 (29%), Positives = 103/208 (49%), Gaps = 17/208 (8%)
 Frame = +1

Query: 367 IENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLV 546
           I  L    +L  L +    IR+I  LE   +L+ L I+   +  IEG+     L+KL+L 
Sbjct: 47  IVGLSLFHNLSSLTIVAQDIREISGLETCLQLKELWIAECCIEKIEGLQGCRNLEKLYLY 106

Query: 547 NNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKL-QNLDALTN 723
            NKI+KIENL  L +L++L L  N I+ IE + TL NL+ L L  N ++ + + LD    
Sbjct: 107 YNKISKIENLEKLIKLEVLWLNHNMIKNIEGLQTLKNLKDLNLAGNLVSSIGRCLDPNEQ 166

Query: 724 LTVLSMQSNRLTKIEGLQSLVNLREL----------------YLSHNGIEVIEGLDSNNK 855
           L  L++  N++T  + L +L  L  L                 L +    V+  L S  +
Sbjct: 167 LEKLNLSGNQITSFKDLTNLTKLTRLKDLCLNDPQYKSNPVCQLCNYSTHVLYHLPSLQR 226

Query: 856 LTMLDIASNRIKKIENVSHLTELQEFWM 939
           L   D+++ +IK++ + + + ++  + M
Sbjct: 227 LDTFDVSAKQIKELADSTAMKKIMYYNM 254



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 48/127 (37%), Positives = 76/127 (59%), Gaps = 1/127 (0%)
 Frame = +1

Query: 292 IGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEIL 471
           I +I G E   ++K L + +  I+ IE L+  ++L +L LY N+I KIENLE L +LE+L
Sbjct: 66  IREISGLETCLQLKELWIAECCIEKIEGLQGCRNLEKLYLYYNKISKIENLEKLIKLEVL 125

Query: 472 DISFNLLRSIEGVDKLTRLKKLFLVNNKINKIEN-LSSLRQLQMLELGSNRIRAIENVDT 648
            ++ N++++IEG+  L  LK L L  N ++ I   L    QL+ L L  N+I + +++  
Sbjct: 126 WLNHNMIKNIEGLQTLKNLKDLNLAGNLVSSIGRCLDPNEQLEKLNLSGNQITSFKDLTN 185

Query: 649 LTNLESL 669
           LT L  L
Sbjct: 186 LTKLTRL 192



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 52/150 (34%), Positives = 77/150 (51%), Gaps = 5/150 (3%)
 Frame = +1

Query: 454  TELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAI 633
            +++  L++    L  I  ++KL  LK     NN ++K+E L S   L+ L L  N I  I
Sbjct: 878  SKITALNLDGQHLFEITNLEKLENLKWASFSNNNLSKMEGLESCVNLEELTLDGNCISKI 937

Query: 634  ENVDTLTNLESLFLGKNKITKLQN--LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYL 807
            E +  LT L  L +  N +T L+    D L +L  LS+++NR+T +  LQ    L ELY+
Sbjct: 938  EGITRLTKLSRLSMNNNLLTGLEKHTFDNLLHLHSLSLENNRITSLSALQKTFTLIELYI 997

Query: 808  SHNGIEV---IEGLDSNNKLTMLDIASNRI 888
            S+N I V   I  L     L +LD+  N I
Sbjct: 998  SNNYIAVNQEIYNLKGLCNLVILDMYGNII 1027



 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 74/255 (29%), Positives = 117/255 (45%), Gaps = 19/255 (7%)
 Frame = +1

Query: 265  EDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCI-ENLEAL----QSLRELDLYDNQIR 429
            E +D +H  +  +EGF  L K+K L L  N +K   E +  L     SL  LD+  N  +
Sbjct: 732  EYLDASHNHVITLEGFRGLMKLKHLDLSWNQLKKTGEEINVLCKHTTSLLTLDIQHNPWQ 791

Query: 430  K--------IENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSL 585
            K        I  L+ LT L+ L IS    R+       T++ +L L+ +  +K E    L
Sbjct: 792  KPATLRLSVIGRLKTLTHLDGLVISEEETRAALKFISGTKITQLTLLQHSSSKEERPRML 851

Query: 586  RQLQMLELGSNRIRAIENVDTLTN----LESLFLGKNKITKLQNLDALTNLTVLSMQSNR 753
                  ++ +   +   +     N    + +L L    + ++ NL+ L NL   S  +N 
Sbjct: 852  STWPSAKILTQISKLGPHFHLTGNWYSKITALNLDGQHLFEITNLEKLENLKWASFSNNN 911

Query: 754  LTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIE--NVSHLTELQ 927
            L+K+EGL+S VNL EL L  N I  IEG+    KL+ L + +N +  +E     +L  L 
Sbjct: 912  LSKMEGLESCVNLEELTLDGNCISKIEGITRLTKLSRLSMNNNLLTGLEKHTFDNLLHLH 971

Query: 928  EFWMNDNLLESWSDL 972
               + +N + S S L
Sbjct: 972  SLSLENNRITSLSAL 986



 Score = 71.6 bits (174), Expect = 9e-13
 Identities = 67/281 (23%), Positives = 122/281 (43%), Gaps = 39/281 (13%)
 Frame = +1

Query: 229  VDMETINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELD 408
            + +   N+     +++L+   + K+     L  ++ L +  N   C++++  L +L  LD
Sbjct: 676  ISLAKTNIYSHIVNLNLHGNSLSKLRDLAKLTGLRKLNISFNEFTCLDDVYHLYNLEYLD 735

Query: 409  LYDNQIRKIENLEALTELEILDISFNLLRSI-EGVDKL----TRLKKLFLVNN------- 552
               N +  +E    L +L+ LD+S+N L+   E ++ L    T L  L + +N       
Sbjct: 736  ASHNHVITLEGFRGLMKLKHLDLSWNQLKKTGEEINVLCKHTTSLLTLDIQHNPWQKPAT 795

Query: 553  -KINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDAL---- 717
             +++ I  L +L  L  L +     RA     + T +  L L ++  +K +    L    
Sbjct: 796  LRLSVIGRLKTLTHLDGLVISEEETRAALKFISGTKITQLTLLQHSSSKEERPRMLSTWP 855

Query: 718  ----------------------TNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVI 831
                                  + +T L++    L +I  L+ L NL+    S+N +  +
Sbjct: 856  SAKILTQISKLGPHFHLTGNWYSKITALNLDGQHLFEITNLEKLENLKWASFSNNNLSKM 915

Query: 832  EGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLL 954
            EGL+S   L  L +  N I KIE ++ LT+L    MN+NLL
Sbjct: 916  EGLESCVNLEELTLDGNCISKIEGITRLTKLSRLSMNNNLL 956



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 40/125 (32%), Positives = 70/125 (56%)
 Frame = +1

Query: 634  ENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSH 813
            E  DT + LE  F G  +I  L     L++LT+++     + +I GL++ + L+EL+++ 
Sbjct: 30   EGSDT-SKLEMFFSGYPRIVGLSLFHNLSSLTIVAQD---IREISGLETCLQLKELWIAE 85

Query: 814  NGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQ 993
              IE IEGL     L  L +  N+I KIEN+  L +L+  W+N N++++       +G Q
Sbjct: 86   CCIEKIEGLQGCRNLEKLYLYYNKISKIENLEKLIKLEVLWLNHNMIKN------IEGLQ 139

Query: 994  SLETV 1008
            +L+ +
Sbjct: 140  TLKNL 144



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 49/155 (31%), Positives = 75/155 (48%), Gaps = 2/155 (1%)
 Frame = +1

Query: 502 EGVDKLTRLKKLFLVNNKINKI--ENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFL 675
           E +++   +K+L L N    +I  +  S   +L+M   G  RI  +       NL SL +
Sbjct: 5   ENLNRGEIIKELCLCNGLTYEIVGQEGSDTSKLEMFFSGYPRIVGLS---LFHNLSSLTI 61

Query: 676 GKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNK 855
               I ++  L+    L  L +    + KIEGLQ   NL +LYL +N I  IE L+   K
Sbjct: 62  VAQDIREISGLETCLQLKELWIAECCIEKIEGLQGCRNLEKLYLYYNKISKIENLEKLIK 121

Query: 856 LTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
           L +L +  N IK IE +  L  L++  +  NL+ S
Sbjct: 122 LEVLWLNHNMIKNIEGLQTLKNLKDLNLAGNLVSS 156



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 45/143 (31%), Positives = 77/143 (53%), Gaps = 17/143 (11%)
 Frame = +1

Query: 256 RDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKI 435
           R+ E + L + +I KIE  E L K++ L L  N+IK IE L+ L++L++L+L  N +  I
Sbjct: 98  RNLEKLYLYYNKISKIENLEKLIKLEVLWLNHNMIKNIEGLQTLKNLKDLNLAGNLVSSI 157

Query: 436 EN-LEALTELEILDISFNLLRS---IEGVDKLTRLKKLF-------------LVNNKINK 564
              L+   +LE L++S N + S   +  + KLTRLK L              L N   + 
Sbjct: 158 GRCLDPNEQLEKLNLSGNQITSFKDLTNLTKLTRLKDLCLNDPQYKSNPVCQLCNYSTHV 217

Query: 565 IENLSSLRQLQMLELGSNRIRAI 633
           + +L SL++L   ++ + +I+ +
Sbjct: 218 LYHLPSLQRLDTFDVSAKQIKEL 240



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 30/100 (30%), Positives = 55/100 (55%)
 Frame = +1

Query: 595 QMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGL 774
           +++ L    I ++   +  +++ +L L  N ++KL++L  LT L  L++  N  T ++ +
Sbjct: 666 KLISLDEKTIISLAKTNIYSHIVNLNLHGNSLSKLRDLAKLTGLRKLNISFNEFTCLDDV 725

Query: 775 QSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKK 894
             L NL  L  SHN +  +EG     KL  LD++ N++KK
Sbjct: 726 YHLYNLEYLDASHNHVITLEGFRGLMKLKHLDLSWNQLKK 765


>ref|NP_001136201.1| leucine-rich repeat-containing protein 9 isoform 3 [Mus musculus].
          Length = 704

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 66/196 (33%), Positives = 106/196 (54%), Gaps = 4/196 (2%)
 Frame = +1

Query: 370 ENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVN 549
           ENL   + ++EL L +    +I   E  ++   L++ F+    I G+     L  L +V 
Sbjct: 5   ENLNRGEIIKELCLCNGLTYEIVGQEG-SDTSKLEMFFSGYPRIVGLSLFHNLSSLTIVA 63

Query: 550 NKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLT 729
             I +I  L +  QL+ L +    I  IE +    NLE L+L  NKI+K++NL+ L  L 
Sbjct: 64  QDIREISGLETCLQLKELWIAECCIEKIEGLQGCRNLEKLYLYYNKISKIENLEKLIKLE 123

Query: 730 VLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVI-EGLDSNNKLTMLDIASNRI---KKI 897
           VL +  N +  IEGLQ+L NL++L L+ N +  I   LD N +L  L+++ N+I   K +
Sbjct: 124 VLWLNHNMIKNIEGLQTLKNLKDLNLAGNLVSSIGRCLDPNEQLEKLNLSGNQITSFKDL 183

Query: 898 ENVSHLTELQEFWMND 945
            N++ LT L++  +ND
Sbjct: 184 TNLTKLTRLKDLCLND 199



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 61/208 (29%), Positives = 103/208 (49%), Gaps = 17/208 (8%)
 Frame = +1

Query: 367 IENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLV 546
           I  L    +L  L +    IR+I  LE   +L+ L I+   +  IEG+     L+KL+L 
Sbjct: 47  IVGLSLFHNLSSLTIVAQDIREISGLETCLQLKELWIAECCIEKIEGLQGCRNLEKLYLY 106

Query: 547 NNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKL-QNLDALTN 723
            NKI+KIENL  L +L++L L  N I+ IE + TL NL+ L L  N ++ + + LD    
Sbjct: 107 YNKISKIENLEKLIKLEVLWLNHNMIKNIEGLQTLKNLKDLNLAGNLVSSIGRCLDPNEQ 166

Query: 724 LTVLSMQSNRLTKIEGLQSLVNLREL----------------YLSHNGIEVIEGLDSNNK 855
           L  L++  N++T  + L +L  L  L                 L +    V+  L S  +
Sbjct: 167 LEKLNLSGNQITSFKDLTNLTKLTRLKDLCLNDPQYKSNPVCQLCNYSTHVLYHLPSLQR 226

Query: 856 LTMLDIASNRIKKIENVSHLTELQEFWM 939
           L   D+++ +IK++ + + + ++  + M
Sbjct: 227 LDTFDVSAKQIKELADSTAMKKIMYYNM 254



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 48/127 (37%), Positives = 76/127 (59%), Gaps = 1/127 (0%)
 Frame = +1

Query: 292 IGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEIL 471
           I +I G E   ++K L + +  I+ IE L+  ++L +L LY N+I KIENLE L +LE+L
Sbjct: 66  IREISGLETCLQLKELWIAECCIEKIEGLQGCRNLEKLYLYYNKISKIENLEKLIKLEVL 125

Query: 472 DISFNLLRSIEGVDKLTRLKKLFLVNNKINKIEN-LSSLRQLQMLELGSNRIRAIENVDT 648
            ++ N++++IEG+  L  LK L L  N ++ I   L    QL+ L L  N+I + +++  
Sbjct: 126 WLNHNMIKNIEGLQTLKNLKDLNLAGNLVSSIGRCLDPNEQLEKLNLSGNQITSFKDLTN 185

Query: 649 LTNLESL 669
           LT L  L
Sbjct: 186 LTKLTRL 192



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 40/125 (32%), Positives = 70/125 (56%)
 Frame = +1

Query: 634  ENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSH 813
            E  DT + LE  F G  +I  L     L++LT+++     + +I GL++ + L+EL+++ 
Sbjct: 30   EGSDT-SKLEMFFSGYPRIVGLSLFHNLSSLTIVAQD---IREISGLETCLQLKELWIAE 85

Query: 814  NGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQ 993
              IE IEGL     L  L +  N+I KIEN+  L +L+  W+N N++++       +G Q
Sbjct: 86   CCIEKIEGLQGCRNLEKLYLYYNKISKIENLEKLIKLEVLWLNHNMIKN------IEGLQ 139

Query: 994  SLETV 1008
            +L+ +
Sbjct: 140  TLKNL 144



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 49/155 (31%), Positives = 75/155 (48%), Gaps = 2/155 (1%)
 Frame = +1

Query: 502 EGVDKLTRLKKLFLVNNKINKI--ENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFL 675
           E +++   +K+L L N    +I  +  S   +L+M   G  RI  +       NL SL +
Sbjct: 5   ENLNRGEIIKELCLCNGLTYEIVGQEGSDTSKLEMFFSGYPRIVGLS---LFHNLSSLTI 61

Query: 676 GKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNK 855
               I ++  L+    L  L +    + KIEGLQ   NL +LYL +N I  IE L+   K
Sbjct: 62  VAQDIREISGLETCLQLKELWIAECCIEKIEGLQGCRNLEKLYLYYNKISKIENLEKLIK 121

Query: 856 LTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
           L +L +  N IK IE +  L  L++  +  NL+ S
Sbjct: 122 LEVLWLNHNMIKNIEGLQTLKNLKDLNLAGNLVSS 156



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 45/143 (31%), Positives = 77/143 (53%), Gaps = 17/143 (11%)
 Frame = +1

Query: 256 RDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKI 435
           R+ E + L + +I KIE  E L K++ L L  N+IK IE L+ L++L++L+L  N +  I
Sbjct: 98  RNLEKLYLYYNKISKIENLEKLIKLEVLWLNHNMIKNIEGLQTLKNLKDLNLAGNLVSSI 157

Query: 436 EN-LEALTELEILDISFNLLRS---IEGVDKLTRLKKLF-------------LVNNKINK 564
              L+   +LE L++S N + S   +  + KLTRLK L              L N   + 
Sbjct: 158 GRCLDPNEQLEKLNLSGNQITSFKDLTNLTKLTRLKDLCLNDPQYKSNPVCQLCNYSTHV 217

Query: 565 IENLSSLRQLQMLELGSNRIRAI 633
           + +L SL++L   ++ + +I+ +
Sbjct: 218 LYHLPSLQRLDTFDVSAKQIKEL 240


>ref|NP_796126.4| leucine-rich repeats and immunoglobulin-like domains protein 3
           precursor [Mus musculus].
          Length = 1117

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 84/257 (32%), Positives = 133/257 (51%), Gaps = 42/257 (16%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEV--LRKVKTLCLRQNLIKCIENLEALQS-LRELDLYDNQIRKI-- 435
           +DL+H R+  I+   +  L+ ++ + L  N ++ I NL ++ + +R+L L  N I KI  
Sbjct: 79  LDLSHNRLSFIQTSSLSHLQSLQEVKLNNNELETIPNLGSISANIRQLSLAGNAIDKILP 138

Query: 436 ENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIE-----NLSS------ 582
           E LEA   LE LD+S N +  +       +LK L++ NN+++ +E     NL+S      
Sbjct: 139 EQLEAFQSLETLDLSNNNISELRTAFPPLQLKYLYINNNRVSSMEPGYFDNLASTLLVLK 198

Query: 583 ---------------LRQLQMLELGSNRIRAIENVDTLT-----NLESLFLGKNKITKLQ 702
                          L QLQ LEL  N+I+   NVD LT      L+SL + +N +TKL 
Sbjct: 199 LNRNRISAIPPKMFKLPQLQHLELNRNKIK---NVDGLTFQGLGALKSLKMQRNGVTKLM 255

Query: 703 N--LDALTNLTVLSMQSNRLTKIE--GLQSLVNLRELYLSHNGIEVI--EGLDSNNKLTM 864
           +     L+N+ VL +  N LT+I    L  L+ LREL+LS N I  I  +  +   KL+ 
Sbjct: 256 DGAFWGLSNMEVLQLDHNNLTEITKGWLYGLLMLRELHLSQNAINRISPDAWEFCQKLSE 315

Query: 865 LDIASNRIKKIENVSHL 915
           LD+  N + ++++ S L
Sbjct: 316 LDLTFNHLSRLDDSSFL 332


>ref|NP_001157031.1| leucine-rich repeat and IQ domain-containing protein 1 isoform 1 [Mus
            musculus].
          Length = 1673

 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 64/217 (29%), Positives = 111/217 (51%), Gaps = 2/217 (0%)
 Frame = +1

Query: 328  VKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEG 507
            ++ L LR+  +  ++ L     L+ +D  +N I  I + E L  L ++ ++ NLL SI G
Sbjct: 833  LQILSLRRCGLTSLQGLSHCTRLKYIDAQENHIEAI-SCENLENLSVVLLNNNLLTSIHG 891

Query: 508  VDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNK 687
             D  T L+ L L +NKI +I  L SL+ LQ L +  N++ + + +     +  L    N 
Sbjct: 892  FDGCTNLQSLELSHNKITRISGLESLKYLQELTVDHNQLISTKGLCEAPTIVYLDCSHNH 951

Query: 688  ITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDS--NNKLT 861
            +T +  +     L ++ +Q N L +   L++ V LREL+L  N I  +EGL S     L 
Sbjct: 952  LTGIDGIGNCGLLQIIKLQGNYLREPPSLRNHVLLRELHLDDNSISSVEGLSSCWLPLLQ 1011

Query: 862  MLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
             L I+ N +  I  + HL  L++  +++N L   +++
Sbjct: 1012 YLSISQNSLATIVPLFHLVSLEKLDVSNNCLSDLTNV 1048



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 53/188 (28%), Positives = 92/188 (48%), Gaps = 6/188 (3%)
 Frame = +1

Query: 277  LNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALT 456
            LN+  +  I GF+    +++L L  N I  I  LE+L+ L+EL +  NQ+   + L    
Sbjct: 881  LNNNLLTSIHGFDGCTNLQSLELSHNKITRISGLESLKYLQELTVDHNQLISTKGLCEAP 940

Query: 457  ELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIE 636
             +  LD S N L  I+G+     L+ + L  N + +  +L +   L+ L L  N I ++E
Sbjct: 941  TIVYLDCSHNHLTGIDGIGNCGLLQIIKLQGNYLREPPSLRNHVLLRELHLDDNSISSVE 1000

Query: 637  NVDT--LTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVN----LRE 798
             + +  L  L+ L + +N +  +  L  L +L  L + +N L+ +  +    N    LRE
Sbjct: 1001 GLSSCWLPLLQYLSISQNSLATIVPLFHLVSLEKLDVSNNCLSDLTNVMCWFNACYSLRE 1060

Query: 799  LYLSHNGI 822
            L L+ N +
Sbjct: 1061 LCLTGNPV 1068


>ref|NP_083162.1| leucine-rich repeat and guanylate kinase domain-containing protein
           [Mus musculus].
          Length = 820

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 61/205 (29%), Positives = 107/205 (52%), Gaps = 4/205 (1%)
 Frame = +1

Query: 322 RKVKTLCLRQNLIKC----IENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNL 489
           R  + + L  NL  C    I  L     L++L+L  N+I  +  +  +  L  L+ S N 
Sbjct: 123 RGTEQVYLNLNLSHCELVDISILCGYVHLQKLNLSGNRIEDLSCVSCMPYLLELNASQNK 182

Query: 490 LRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESL 669
           L +         LKK+   +N I+++ +LS+   L  L L +N I  I  ++   +L  L
Sbjct: 183 LTTFFNFKPPQNLKKVDFSSNLISEMYDLSAYHTLTQLILDNNEIEEITGLENCISLTHL 242

Query: 670 FLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSN 849
            L  NKIT ++ L  L  + VLS+ +N +  I GL+ L  L+ L LSHN I  ++GL+++
Sbjct: 243 SLAGNKITTIKGLGTLP-IKVLSLSNNMIETITGLEELKALQNLDLSHNQISSLQGLENH 301

Query: 850 NKLTMLDIASNRIKKIENVSHLTEL 924
           + L ++++  N+IK++  + ++  L
Sbjct: 302 DLLEVINLEDNKIKELSEIEYIENL 326



 Score = 79.0 bits (193), Expect = 6e-15
 Identities = 56/208 (26%), Positives = 103/208 (49%)
 Frame = +1

Query: 403  LDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSS 582
            L+L   ++  I  L     L+ L++S N +  +  V  +  L +L    NK+    N   
Sbjct: 132  LNLSHCELVDISILCGYVHLQKLNLSGNRIEDLSCVSCMPYLLELNASQNKLTTFFNFKP 191

Query: 583  LRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTK 762
             + L+ ++  SN I  + ++     L  L L  N+I ++  L+   +LT LS+  N++T 
Sbjct: 192  PQNLKKVDFSSNLISEMYDLSAYHTLTQLILDNNEIEEITGLENCISLTHLSLAGNKITT 251

Query: 763  IEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMN 942
            I+GL +L  ++ L LS+N IE I GL+    L  LD++ N+I  ++ + +   L+   + 
Sbjct: 252  IKGLGTLP-IKVLSLSNNMIETITGLEELKALQNLDLSHNQISSLQGLENHDLLEVINLE 310

Query: 943  DNLLESWSDLX*AQGAQSLETVYLERTP 1026
            DN ++  S++   +    L  + L R P
Sbjct: 311  DNKIKELSEIEYIENLPILRVLNLLRNP 338



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 46/142 (32%), Positives = 78/142 (54%)
 Frame = +1

Query: 310 FEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNL 489
           F+  + +K +    NLI  + +L A  +L +L L +N+I +I  LE    L  L ++ N 
Sbjct: 189 FKPPQNLKKVDFSSNLISEMYDLSAYHTLTQLILDNNEIEEITGLENCISLTHLSLAGNK 248

Query: 490 LRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESL 669
           + +I+G+  L  +K L L NN I  I  L  L+ LQ L+L  N+I +++ ++    LE +
Sbjct: 249 ITTIKGLGTLP-IKVLSLSNNMIETITGLEELKALQNLDLSHNQISSLQGLENHDLLEVI 307

Query: 670 FLGKNKITKLQNLDALTNLTVL 735
            L  NKI +L  ++ + NL +L
Sbjct: 308 NLEDNKIKELSEIEYIENLPIL 329



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 56/193 (29%), Positives = 98/193 (50%), Gaps = 6/193 (3%)
 Frame = +1

Query: 265 EDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENL 444
           + ++L+  RI  +     +  +  L   QN +    N +  Q+L+++D   N I ++ +L
Sbjct: 152 QKLNLSGNRIEDLSCVSCMPYLLELNASQNKLTTFFNFKPPQNLKKVDFSSNLISEMYDL 211

Query: 445 EALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRI 624
            A   L  L +  N +  I G++    L  L L  NKI  I+ L +L  +++L L +N I
Sbjct: 212 SAYHTLTQLILDNNEIEEITGLENCISLTHLSLAGNKITTIKGLGTL-PIKVLSLSNNMI 270

Query: 625 RAI---ENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNR---LTKIEGLQSLV 786
             I   E +  L NL+   L  N+I+ LQ L+    L V++++ N+   L++IE +++L 
Sbjct: 271 ETITGLEELKALQNLD---LSHNQISSLQGLENHDLLEVINLEDNKIKELSEIEYIENLP 327

Query: 787 NLRELYLSHNGIE 825
            LR L L  N I+
Sbjct: 328 ILRVLNLLRNPIQ 340



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 57/199 (28%), Positives = 91/199 (45%)
 Frame = +1

Query: 406  DLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSL 585
            D YD  +R+    EA+T L          R  E V     L    LV+  I     L   
Sbjct: 100  DKYDGILREETVAEAITGLGWSG------RGTEQVYLNLNLSHCELVDISI-----LCGY 148

Query: 586  RQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKI 765
              LQ L L  NRI  +  V  +  L  L   +NK+T   N     NL  +   SN ++++
Sbjct: 149  VHLQKLNLSGNRIEDLSCVSCMPYLLELNASQNKLTTFFNFKPPQNLKKVDFSSNLISEM 208

Query: 766  EGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMND 945
              L +   L +L L +N IE I GL++   LT L +A N+I  I+ +  L  ++   +++
Sbjct: 209  YDLSAYHTLTQLILDNNEIEEITGLENCISLTHLSLAGNKITTIKGLGTL-PIKVLSLSN 267

Query: 946  NLLESWSDLX*AQGAQSLE 1002
            N++E+ + L   +  Q+L+
Sbjct: 268  NMIETITGLEELKALQNLD 286



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 36/124 (29%), Positives = 63/124 (50%), Gaps = 6/124 (4%)
 Frame = +1

Query: 289 RIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEI 468
           +I  I+G   L  +K L L  N+I+ I  LE L++L+ LDL  NQI  ++ LE    LE+
Sbjct: 248 KITTIKGLGTL-PIKVLSLSNNMIETITGLEELKALQNLDLSHNQISSLQGLENHDLLEV 306

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSS------LRQLQMLELGSNRIRA 630
           +++  N ++ +  ++ +  L  L ++N   N I+             L++ EL   +I+ 
Sbjct: 307 INLEDNKIKELSEIEYIENLPILRVLNLLRNPIQTKPEYWFFVIYMLLRLTELDQQKIKV 366

Query: 631 IENV 642
            E V
Sbjct: 367 EEKV 370


  Database: RefSeq49_MP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 15,617,559
  Number of sequences in database:  30,036
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 30036
Number of Hits to DB: 26,991,599
Number of extensions: 628604
Number of successful extensions: 2957
Number of sequences better than 1.0e-05: 85
Number of HSP's gapped: 2743
Number of HSP's successfully gapped: 208
Length of query: 346
Length of database: 15,617,559
Length adjustment: 102
Effective length of query: 244
Effective length of database: 12,553,887
Effective search space: 3063148428
Effective search space used: 3063148428
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 34 (17.7 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007857
         (1040 letters)

Database: RefSeq49_HP.fasta 
           32,964 sequences; 18,297,164 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_002703.1| protein phosphatase 1 regulatory subunit 7 [Hom...   530   e-151
Alignment   gi|NP_001185947.1| leucine-rich repeat-containing protein 49 is...    99   5e-21
Alignment   gi|NP_001185946.1| leucine-rich repeat-containing protein 49 is...    99   5e-21
Alignment   gi|NP_060161.2| leucine-rich repeat-containing protein 49 isofo...    99   5e-21
Alignment   gi|NP_001123564.1| leucine-rich repeat-containing protein 48 is...    90   4e-18
Alignment   gi|NP_001123563.1| leucine-rich repeat-containing protein 48 is...    90   4e-18
Alignment   gi|NP_112584.3| leucine-rich repeat-containing protein 48 isofo...    90   4e-18
Alignment   gi|NP_001123562.1| leucine-rich repeat-containing protein 48 is...    90   4e-18
Alignment   gi|NP_653249.1| leucine-rich repeat and guanylate kinase domain...    86   4e-17
Alignment   gi|NP_848547.4| dynein assembly factor 1, axonemal [Homo sapien...    86   6e-17

>ref|NP_002703.1| protein phosphatase 1 regulatory subunit 7 [Homo sapiens].
          Length = 360

 Score =  530 bits (1366), Expect = e-151
 Identities = 280/335 (83%), Positives = 294/335 (87%)
 Frame = +1

Query: 31   MAAERGTGQQQSQEMMEVDRRVXXXXXXXXXXXXXXXXIVADLSEHSLKDXXXXXXXXXX 210
            MAAERG GQQQSQEMMEVDRRV                IVADLSE SLKD          
Sbjct: 1    MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHSSGIVADLSEQSLKDGEERGEEDPE 60

Query: 211  XXXXXXVDMETINLDRDAEDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQ 390
                  VDMETINLDRDAEDVDLNHYRIGKIEGFEVL+KVKTLCLRQNLIKCIENLE LQ
Sbjct: 61   EEHELPVDMETINLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQ 120

Query: 391  SLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIE 570
            SLRELDLYDNQI+KIENLEALTELEILDISFNLLR+IEGVDKLTRLKKLFLVNNKI+KIE
Sbjct: 121  SLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIE 180

Query: 571  NLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 750
            NLS+L QLQMLELGSNRIRAIEN+DTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN
Sbjct: 181  NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSN 240

Query: 751  RLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQE 930
            RLTKIEGLQ+LVNLRELYLSHNGIEVIEGL++NNKLTMLDIASNRIKKIEN+SHLTELQE
Sbjct: 241  RLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQE 300

Query: 931  FWMNDNLLESWSDLX*AQGAQSLETVYLERTPCRR 1035
            FWMNDNLLESWSDL   +GA+SLETVYLER P ++
Sbjct: 301  FWMNDNLLESWSDLDELKGARSLETVYLERNPLQK 335



 Score = 62.0 bits (149), Expect = 9e-10
 Identities = 42/111 (37%), Positives = 61/111 (54%)
 Frame = +1

Query: 289 RIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEI 468
           R+ KIEG + L  ++ L L  N I+ IE LE    L  LD+  N+I+KIEN+  LTEL+ 
Sbjct: 241 RLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQE 300

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNR 621
             ++ NLL S   +D+L   + L  V  + N ++     R+  ML L S R
Sbjct: 301 FWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVR 351


>ref|NP_001185947.1| leucine-rich repeat-containing protein 49 isoform 3 [Homo sapiens].
          Length = 642

 Score = 99.4 bits (246), Expect = 5e-21
 Identities = 64/192 (33%), Positives = 106/192 (55%), Gaps = 5/192 (2%)
 Frame = +1

Query: 460  LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIEN 639
            L +L+   N +  I+ +  L +L  L L +N+I +I  LS+LR L++L LG NRI+ I N
Sbjct: 70   LRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISN 129

Query: 640  VDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNG 819
            ++ L +L+ L L  N+ITK++N++ L  L VL++  N L+ ++ L  L +L EL L HN 
Sbjct: 130  LENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQ 189

Query: 820  IEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTE---LQEFWMNDNLL--ESWSDLX*AQ 984
            I  +  +D+   L  L ++ N I   ++VS L +   L +   + N +  ESW      Q
Sbjct: 190  ITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQ 249

Query: 985  GAQSLETVYLER 1020
                L  + ++R
Sbjct: 250  NMMQLRQLDMKR 261



 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 56/167 (33%), Positives = 96/167 (57%)
 Frame = +1

Query: 526  LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
            L+ L   +N I +I+N+S+L++L  L+L  N+I  I  + TL  L  L LGKN+I K+ N
Sbjct: 70   LRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISN 129

Query: 706  LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNR 885
            L+ L +L VL +  N++TKIE +  L  LR L L+ N +  ++ L+  + LT L++  N+
Sbjct: 130  LENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQ 189

Query: 886  IKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERTP 1026
            I  + +V +L  LQ  +++ N + S+  +     + SL  +  +  P
Sbjct: 190  ITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNP 236



 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 66/212 (31%), Positives = 109/212 (51%), Gaps = 3/212 (1%)
 Frame = +1

Query: 346 RQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTR 525
           RQ L  C   +     LR L+   N I +I+N+  L +L  LD+  N +  I G+  L  
Sbjct: 55  RQKLTVC-PIINGEDHLRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRC 113

Query: 526 LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
           L+ L L  N+I KI NL +L+ L +L+L  N+I  IEN++ L  L  L L +N ++ + N
Sbjct: 114 LRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDN 173

Query: 706 LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGI---EVIEGLDSNNKLTMLDIA 876
           L+ L +LT L+++ N++T +  + +L  L+ L+LS N I   + +  L  ++ L+ +   
Sbjct: 174 LNGLDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFD 233

Query: 877 SNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            N I            QE W    +L++   L
Sbjct: 234 GNPI-----------AQESWYKHTVLQNMMQL 254



 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 61/185 (32%), Positives = 101/185 (54%), Gaps = 8/185 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           ++  H  I +I+    L+K+ +L L  N I+ I  L  L+ LR L L  N+I+KI NLE 
Sbjct: 73  LNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNLEN 132

Query: 451 LTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRA 630
           L  L++LD+  N +  IE ++ L  L+ L L  N ++ ++NL+ L  L  L L  N+I  
Sbjct: 133 LKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITF 192

Query: 631 IENVDTLTNLESLFLGKNKITKLQNLDAL---TNLTVLSMQSNRLT-----KIEGLQSLV 786
           + +VD L  L+ LFL  N I+   ++  L   ++L+ ++   N +      K   LQ+++
Sbjct: 193 VRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMM 252

Query: 787 NLREL 801
            LR+L
Sbjct: 253 QLRQL 257



 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 41/124 (33%), Positives = 65/124 (52%)
 Frame = +1

Query: 601 LELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQS 780
           L L   ++     ++   +L  L    N IT++QN+  L  L  L +  N++ +I GL +
Sbjct: 51  LSLERQKLTVCPIINGEDHLRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLST 110

Query: 781 LVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
           L  LR L L  N I+ I  L++   L +LD+  N+I KIEN++HL EL+   +  N L  
Sbjct: 111 LRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSH 170

Query: 961 WSDL 972
             +L
Sbjct: 171 VDNL 174



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 48/154 (31%), Positives = 78/154 (50%)
 Frame = +1

Query: 487 LLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLES 666
           L RS E  +K+    +L L   K+     ++    L++L    N I  I+N+  L  L S
Sbjct: 37  LQRSSE--EKILYSDRLSLERQKLTVCPIINGEDHLRLLNFQHNFITRIQNISNLQKLIS 94

Query: 667 LFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDS 846
           L L  N+I ++  L  L  L VL +  NR+ KI  L++L +L  L L  N I  IE ++ 
Sbjct: 95  LDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENINH 154

Query: 847 NNKLTMLDIASNRIKKIENVSHLTELQEFWMNDN 948
             +L +L++A N +  ++N++ L  L E  +  N
Sbjct: 155 LCELRVLNLARNFLSHVDNLNGLDSLTELNLRHN 188


>ref|NP_001185946.1| leucine-rich repeat-containing protein 49 isoform 1 [Homo sapiens].
          Length = 691

 Score = 99.4 bits (246), Expect = 5e-21
 Identities = 64/192 (33%), Positives = 106/192 (55%), Gaps = 5/192 (2%)
 Frame = +1

Query: 460  LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIEN 639
            L +L+   N +  I+ +  L +L  L L +N+I +I  LS+LR L++L LG NRI+ I N
Sbjct: 119  LRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISN 178

Query: 640  VDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNG 819
            ++ L +L+ L L  N+ITK++N++ L  L VL++  N L+ ++ L  L +L EL L HN 
Sbjct: 179  LENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQ 238

Query: 820  IEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTE---LQEFWMNDNLL--ESWSDLX*AQ 984
            I  +  +D+   L  L ++ N I   ++VS L +   L +   + N +  ESW      Q
Sbjct: 239  ITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQ 298

Query: 985  GAQSLETVYLER 1020
                L  + ++R
Sbjct: 299  NMMQLRQLDMKR 310



 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 56/167 (33%), Positives = 96/167 (57%)
 Frame = +1

Query: 526  LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
            L+ L   +N I +I+N+S+L++L  L+L  N+I  I  + TL  L  L LGKN+I K+ N
Sbjct: 119  LRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISN 178

Query: 706  LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNR 885
            L+ L +L VL +  N++TKIE +  L  LR L L+ N +  ++ L+  + LT L++  N+
Sbjct: 179  LENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQ 238

Query: 886  IKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERTP 1026
            I  + +V +L  LQ  +++ N + S+  +     + SL  +  +  P
Sbjct: 239  ITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNP 285



 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 66/212 (31%), Positives = 109/212 (51%), Gaps = 3/212 (1%)
 Frame = +1

Query: 346 RQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTR 525
           RQ L  C   +     LR L+   N I +I+N+  L +L  LD+  N +  I G+  L  
Sbjct: 104 RQKLTVC-PIINGEDHLRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRC 162

Query: 526 LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
           L+ L L  N+I KI NL +L+ L +L+L  N+I  IEN++ L  L  L L +N ++ + N
Sbjct: 163 LRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDN 222

Query: 706 LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGI---EVIEGLDSNNKLTMLDIA 876
           L+ L +LT L+++ N++T +  + +L  L+ L+LS N I   + +  L  ++ L+ +   
Sbjct: 223 LNGLDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFD 282

Query: 877 SNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            N I            QE W    +L++   L
Sbjct: 283 GNPI-----------AQESWYKHTVLQNMMQL 303



 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 61/185 (32%), Positives = 101/185 (54%), Gaps = 8/185 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           ++  H  I +I+    L+K+ +L L  N I+ I  L  L+ LR L L  N+I+KI NLE 
Sbjct: 122 LNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNLEN 181

Query: 451 LTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRA 630
           L  L++LD+  N +  IE ++ L  L+ L L  N ++ ++NL+ L  L  L L  N+I  
Sbjct: 182 LKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITF 241

Query: 631 IENVDTLTNLESLFLGKNKITKLQNLDAL---TNLTVLSMQSNRLT-----KIEGLQSLV 786
           + +VD L  L+ LFL  N I+   ++  L   ++L+ ++   N +      K   LQ+++
Sbjct: 242 VRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMM 301

Query: 787 NLREL 801
            LR+L
Sbjct: 302 QLRQL 306



 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 41/124 (33%), Positives = 65/124 (52%)
 Frame = +1

Query: 601 LELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQS 780
           L L   ++     ++   +L  L    N IT++QN+  L  L  L +  N++ +I GL +
Sbjct: 100 LSLERQKLTVCPIINGEDHLRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLST 159

Query: 781 LVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
           L  LR L L  N I+ I  L++   L +LD+  N+I KIEN++HL EL+   +  N L  
Sbjct: 160 LRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSH 219

Query: 961 WSDL 972
             +L
Sbjct: 220 VDNL 223



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 48/154 (31%), Positives = 78/154 (50%)
 Frame = +1

Query: 487 LLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLES 666
           L RS E  +K+    +L L   K+     ++    L++L    N I  I+N+  L  L S
Sbjct: 86  LQRSSE--EKILYSDRLSLERQKLTVCPIINGEDHLRLLNFQHNFITRIQNISNLQKLIS 143

Query: 667 LFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDS 846
           L L  N+I ++  L  L  L VL +  NR+ KI  L++L +L  L L  N I  IE ++ 
Sbjct: 144 LDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENINH 203

Query: 847 NNKLTMLDIASNRIKKIENVSHLTELQEFWMNDN 948
             +L +L++A N +  ++N++ L  L E  +  N
Sbjct: 204 LCELRVLNLARNFLSHVDNLNGLDSLTELNLRHN 237


>ref|NP_060161.2| leucine-rich repeat-containing protein 49 isoform 2 [Homo sapiens].
          Length = 686

 Score = 99.4 bits (246), Expect = 5e-21
 Identities = 64/192 (33%), Positives = 106/192 (55%), Gaps = 5/192 (2%)
 Frame = +1

Query: 460  LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIEN 639
            L +L+   N +  I+ +  L +L  L L +N+I +I  LS+LR L++L LG NRI+ I N
Sbjct: 114  LRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISN 173

Query: 640  VDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNG 819
            ++ L +L+ L L  N+ITK++N++ L  L VL++  N L+ ++ L  L +L EL L HN 
Sbjct: 174  LENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQ 233

Query: 820  IEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTE---LQEFWMNDNLL--ESWSDLX*AQ 984
            I  +  +D+   L  L ++ N I   ++VS L +   L +   + N +  ESW      Q
Sbjct: 234  ITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQ 293

Query: 985  GAQSLETVYLER 1020
                L  + ++R
Sbjct: 294  NMMQLRQLDMKR 305



 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 56/167 (33%), Positives = 96/167 (57%)
 Frame = +1

Query: 526  LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
            L+ L   +N I +I+N+S+L++L  L+L  N+I  I  + TL  L  L LGKN+I K+ N
Sbjct: 114  LRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISN 173

Query: 706  LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNR 885
            L+ L +L VL +  N++TKIE +  L  LR L L+ N +  ++ L+  + LT L++  N+
Sbjct: 174  LENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQ 233

Query: 886  IKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERTP 1026
            I  + +V +L  LQ  +++ N + S+  +     + SL  +  +  P
Sbjct: 234  ITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNP 280



 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 66/212 (31%), Positives = 109/212 (51%), Gaps = 3/212 (1%)
 Frame = +1

Query: 346 RQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTR 525
           RQ L  C   +     LR L+   N I +I+N+  L +L  LD+  N +  I G+  L  
Sbjct: 99  RQKLTVC-PIINGEDHLRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRC 157

Query: 526 LKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQN 705
           L+ L L  N+I KI NL +L+ L +L+L  N+I  IEN++ L  L  L L +N ++ + N
Sbjct: 158 LRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDN 217

Query: 706 LDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGI---EVIEGLDSNNKLTMLDIA 876
           L+ L +LT L+++ N++T +  + +L  L+ L+LS N I   + +  L  ++ L+ +   
Sbjct: 218 LNGLDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFD 277

Query: 877 SNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
            N I            QE W    +L++   L
Sbjct: 278 GNPI-----------AQESWYKHTVLQNMMQL 298



 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 61/185 (32%), Positives = 101/185 (54%), Gaps = 8/185 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           ++  H  I +I+    L+K+ +L L  N I+ I  L  L+ LR L L  N+I+KI NLE 
Sbjct: 117 LNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNLEN 176

Query: 451 LTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRA 630
           L  L++LD+  N +  IE ++ L  L+ L L  N ++ ++NL+ L  L  L L  N+I  
Sbjct: 177 LKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITF 236

Query: 631 IENVDTLTNLESLFLGKNKITKLQNLDAL---TNLTVLSMQSNRLT-----KIEGLQSLV 786
           + +VD L  L+ LFL  N I+   ++  L   ++L+ ++   N +      K   LQ+++
Sbjct: 237 VRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMM 296

Query: 787 NLREL 801
            LR+L
Sbjct: 297 QLRQL 301



 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 41/124 (33%), Positives = 65/124 (52%)
 Frame = +1

Query: 601 LELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQS 780
           L L   ++     ++   +L  L    N IT++QN+  L  L  L +  N++ +I GL +
Sbjct: 95  LSLERQKLTVCPIINGEDHLRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLST 154

Query: 781 LVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLES 960
           L  LR L L  N I+ I  L++   L +LD+  N+I KIEN++HL EL+   +  N L  
Sbjct: 155 LRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSH 214

Query: 961 WSDL 972
             +L
Sbjct: 215 VDNL 218



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 48/154 (31%), Positives = 78/154 (50%)
 Frame = +1

Query: 487 LLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDTLTNLES 666
           L RS E  +K+    +L L   K+     ++    L++L    N I  I+N+  L  L S
Sbjct: 81  LQRSSE--EKILYSDRLSLERQKLTVCPIINGEDHLRLLNFQHNFITRIQNISNLQKLIS 138

Query: 667 LFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLDS 846
           L L  N+I ++  L  L  L VL +  NR+ KI  L++L +L  L L  N I  IE ++ 
Sbjct: 139 LDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENINH 198

Query: 847 NNKLTMLDIASNRIKKIENVSHLTELQEFWMNDN 948
             +L +L++A N +  ++N++ L  L E  +  N
Sbjct: 199 LCELRVLNLARNFLSHVDNLNGLDSLTELNLRHN 232


>ref|NP_001123564.1| leucine-rich repeat-containing protein 48 isoform b [Homo sapiens].
          Length = 457

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 58/142 (40%), Positives = 89/142 (62%), Gaps = 3/142 (2%)
 Frame = +1

Query: 289 RIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEI 468
           ++ K EG  + + V +L L    I  I+NL   ++LR+L L +N I KIE LE L  L  
Sbjct: 33  QLAKQEGI-LFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVW 91

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDT 648
           LD+SFN + +IEG+D L  L+ L L NN+I+KI++L +L +LQ+L LG+NRI  + N+  
Sbjct: 92  LDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIY 151

Query: 649 LTN---LESLFLGKNKITKLQN 705
           L     L +L L +N I++ ++
Sbjct: 152 LRRFKCLRTLSLSRNPISEAED 173



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 59/174 (33%), Positives = 86/174 (49%), Gaps = 10/174 (5%)
 Frame = +1

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDT 648
           L + F  +  I+ + +   L+KL L NN I KIE L +L  L  L+L  N I  IE +DT
Sbjct: 48  LQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDT 107

Query: 649 LTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEG---LQSLVNLRELYLSHNG 819
           L NLE L L  N+I+K+ +LDAL  L VLS+ +NR+  +     L+    LR L LS N 
Sbjct: 108 LVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNP 167

Query: 820 IEVIEGLDSNNKLTMLDI-------ASNRIKKIENVSHLTELQEFWMNDNLLES 960
           I   E         + D+         +  KK+    H   + E    +NL+++
Sbjct: 168 ISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQA 221



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 44/121 (36%), Positives = 69/121 (57%)
 Frame = +1

Query: 664  SLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLD 843
            SL L    I ++ NL    NL  L + +N + KIEGL++L +L  L LS N IE IEGLD
Sbjct: 47   SLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLD 106

Query: 844  SNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERT 1023
            +   L  L + +NRI KI+++  L +LQ   + +N +++  ++   +  + L T+ L R 
Sbjct: 107  TLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRN 166

Query: 1024 P 1026
            P
Sbjct: 167  P 167



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 48/123 (39%), Positives = 67/123 (54%), Gaps = 3/123 (2%)
 Frame = +1

Query: 280 NHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTE 459
           N  RI  +  FE LRK++   L  N+I+ IE LE L  L  LDL  N I  IE L+ L  
Sbjct: 54  NILRIDNLWQFENLRKLQ---LDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVN 110

Query: 460 LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQ---LQMLELGSNRIRA 630
           LE L +  N +  I+ +D L +L+ L L NN+I+ + N+  LR+   L+ L L  N I  
Sbjct: 111 LEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISE 170

Query: 631 IEN 639
            E+
Sbjct: 171 AED 173


>ref|NP_001123563.1| leucine-rich repeat-containing protein 48 isoform b [Homo sapiens].
          Length = 457

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 58/142 (40%), Positives = 89/142 (62%), Gaps = 3/142 (2%)
 Frame = +1

Query: 289 RIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEI 468
           ++ K EG  + + V +L L    I  I+NL   ++LR+L L +N I KIE LE L  L  
Sbjct: 33  QLAKQEGI-LFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVW 91

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDT 648
           LD+SFN + +IEG+D L  L+ L L NN+I+KI++L +L +LQ+L LG+NRI  + N+  
Sbjct: 92  LDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIY 151

Query: 649 LTN---LESLFLGKNKITKLQN 705
           L     L +L L +N I++ ++
Sbjct: 152 LRRFKCLRTLSLSRNPISEAED 173



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 59/174 (33%), Positives = 86/174 (49%), Gaps = 10/174 (5%)
 Frame = +1

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDT 648
           L + F  +  I+ + +   L+KL L NN I KIE L +L  L  L+L  N I  IE +DT
Sbjct: 48  LQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDT 107

Query: 649 LTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEG---LQSLVNLRELYLSHNG 819
           L NLE L L  N+I+K+ +LDAL  L VLS+ +NR+  +     L+    LR L LS N 
Sbjct: 108 LVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNP 167

Query: 820 IEVIEGLDSNNKLTMLDI-------ASNRIKKIENVSHLTELQEFWMNDNLLES 960
           I   E         + D+         +  KK+    H   + E    +NL+++
Sbjct: 168 ISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQA 221



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 44/121 (36%), Positives = 69/121 (57%)
 Frame = +1

Query: 664  SLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLD 843
            SL L    I ++ NL    NL  L + +N + KIEGL++L +L  L LS N IE IEGLD
Sbjct: 47   SLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLD 106

Query: 844  SNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERT 1023
            +   L  L + +NRI KI+++  L +LQ   + +N +++  ++   +  + L T+ L R 
Sbjct: 107  TLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRN 166

Query: 1024 P 1026
            P
Sbjct: 167  P 167



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 48/123 (39%), Positives = 67/123 (54%), Gaps = 3/123 (2%)
 Frame = +1

Query: 280 NHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTE 459
           N  RI  +  FE LRK++   L  N+I+ IE LE L  L  LDL  N I  IE L+ L  
Sbjct: 54  NILRIDNLWQFENLRKLQ---LDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVN 110

Query: 460 LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQ---LQMLELGSNRIRA 630
           LE L +  N +  I+ +D L +L+ L L NN+I+ + N+  LR+   L+ L L  N I  
Sbjct: 111 LEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISE 170

Query: 631 IEN 639
            E+
Sbjct: 171 AED 173


>ref|NP_112584.3| leucine-rich repeat-containing protein 48 isoform a [Homo sapiens].
          Length = 523

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 58/142 (40%), Positives = 89/142 (62%), Gaps = 3/142 (2%)
 Frame = +1

Query: 289 RIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEI 468
           ++ K EG  + + V +L L    I  I+NL   ++LR+L L +N I KIE LE L  L  
Sbjct: 33  QLAKQEGI-LFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVW 91

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDT 648
           LD+SFN + +IEG+D L  L+ L L NN+I+KI++L +L +LQ+L LG+NRI  + N+  
Sbjct: 92  LDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIY 151

Query: 649 LTN---LESLFLGKNKITKLQN 705
           L     L +L L +N I++ ++
Sbjct: 152 LRRFKCLRTLSLSRNPISEAED 173



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 59/174 (33%), Positives = 86/174 (49%), Gaps = 10/174 (5%)
 Frame = +1

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDT 648
           L + F  +  I+ + +   L+KL L NN I KIE L +L  L  L+L  N I  IE +DT
Sbjct: 48  LQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDT 107

Query: 649 LTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEG---LQSLVNLRELYLSHNG 819
           L NLE L L  N+I+K+ +LDAL  L VLS+ +NR+  +     L+    LR L LS N 
Sbjct: 108 LVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNP 167

Query: 820 IEVIEGLDSNNKLTMLDI-------ASNRIKKIENVSHLTELQEFWMNDNLLES 960
           I   E         + D+         +  KK+    H   + E    +NL+++
Sbjct: 168 ISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQA 221



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 44/121 (36%), Positives = 69/121 (57%)
 Frame = +1

Query: 664  SLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLD 843
            SL L    I ++ NL    NL  L + +N + KIEGL++L +L  L LS N IE IEGLD
Sbjct: 47   SLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLD 106

Query: 844  SNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERT 1023
            +   L  L + +NRI KI+++  L +LQ   + +N +++  ++   +  + L T+ L R 
Sbjct: 107  TLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRN 166

Query: 1024 P 1026
            P
Sbjct: 167  P 167



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 48/123 (39%), Positives = 67/123 (54%), Gaps = 3/123 (2%)
 Frame = +1

Query: 280 NHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTE 459
           N  RI  +  FE LRK++   L  N+I+ IE LE L  L  LDL  N I  IE L+ L  
Sbjct: 54  NILRIDNLWQFENLRKLQ---LDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVN 110

Query: 460 LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQ---LQMLELGSNRIRA 630
           LE L +  N +  I+ +D L +L+ L L NN+I+ + N+  LR+   L+ L L  N I  
Sbjct: 111 LEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISE 170

Query: 631 IEN 639
            E+
Sbjct: 171 AED 173


>ref|NP_001123562.1| leucine-rich repeat-containing protein 48 isoform a [Homo sapiens].
          Length = 523

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 58/142 (40%), Positives = 89/142 (62%), Gaps = 3/142 (2%)
 Frame = +1

Query: 289 RIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEI 468
           ++ K EG  + + V +L L    I  I+NL   ++LR+L L +N I KIE LE L  L  
Sbjct: 33  QLAKQEGI-LFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVW 91

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDT 648
           LD+SFN + +IEG+D L  L+ L L NN+I+KI++L +L +LQ+L LG+NRI  + N+  
Sbjct: 92  LDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIY 151

Query: 649 LTN---LESLFLGKNKITKLQN 705
           L     L +L L +N I++ ++
Sbjct: 152 LRRFKCLRTLSLSRNPISEAED 173



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 59/174 (33%), Positives = 86/174 (49%), Gaps = 10/174 (5%)
 Frame = +1

Query: 469 LDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENVDT 648
           L + F  +  I+ + +   L+KL L NN I KIE L +L  L  L+L  N I  IE +DT
Sbjct: 48  LQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDT 107

Query: 649 LTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEG---LQSLVNLRELYLSHNG 819
           L NLE L L  N+I+K+ +LDAL  L VLS+ +NR+  +     L+    LR L LS N 
Sbjct: 108 LVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNP 167

Query: 820 IEVIEGLDSNNKLTMLDI-------ASNRIKKIENVSHLTELQEFWMNDNLLES 960
           I   E         + D+         +  KK+    H   + E    +NL+++
Sbjct: 168 ISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQA 221



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 44/121 (36%), Positives = 69/121 (57%)
 Frame = +1

Query: 664  SLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGLD 843
            SL L    I ++ NL    NL  L + +N + KIEGL++L +L  L LS N IE IEGLD
Sbjct: 47   SLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLD 106

Query: 844  SNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSLETVYLERT 1023
            +   L  L + +NRI KI+++  L +LQ   + +N +++  ++   +  + L T+ L R 
Sbjct: 107  TLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRN 166

Query: 1024 P 1026
            P
Sbjct: 167  P 167



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 48/123 (39%), Positives = 67/123 (54%), Gaps = 3/123 (2%)
 Frame = +1

Query: 280 NHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTE 459
           N  RI  +  FE LRK++   L  N+I+ IE LE L  L  LDL  N I  IE L+ L  
Sbjct: 54  NILRIDNLWQFENLRKLQ---LDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVN 110

Query: 460 LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQ---LQMLELGSNRIRA 630
           LE L +  N +  I+ +D L +L+ L L NN+I+ + N+  LR+   L+ L L  N I  
Sbjct: 111 LEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISE 170

Query: 631 IEN 639
            E+
Sbjct: 171 AED 173


>ref|NP_653249.1| leucine-rich repeat and guanylate kinase domain-containing protein
           [Homo sapiens].
          Length = 825

 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 54/177 (30%), Positives = 96/177 (54%)
 Frame = +1

Query: 394 LRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIEN 573
           L++LDL  N+I  +  +  +  L  L+ S N L +         LKK    +N+I++I +
Sbjct: 151 LQKLDLSANKIEDLSCVSCMPYLLELNASQNNLTTFFNFKPPKNLKKADFSHNQISEICD 210

Query: 574 LSSLRQLQMLELGSNRIRAIENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNR 753
           LS+   L  L L  N I  I  ++   NL  L L  NKIT +  L+ L  + +L + +N+
Sbjct: 211 LSAYHALTKLILDGNEIEEISGLEMCNNLIHLSLANNKITTINGLNKLP-IKILCLSNNQ 269

Query: 754 LTKIEGLQSLVNLRELYLSHNGIEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTEL 924
           +  I GL+ L  L+ L LSHN I  ++GL++++ L ++++  N+I ++  + ++  L
Sbjct: 270 IEMITGLEDLKALQNLDLSHNQISSLQGLENHDLLEVINLEDNKIAELREIEYIKNL 326



 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 50/189 (26%), Positives = 90/189 (47%)
 Frame = +1

Query: 460  LEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIEN 639
            L+ LD+S N +  +  V  +  L +L    N +    N    + L+  +   N+I  I +
Sbjct: 151  LQKLDLSANKIEDLSCVSCMPYLLELNASQNNLTTFFNFKPPKNLKKADFSHNQISEICD 210

Query: 640  VDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNG 819
            +     L  L L  N+I ++  L+   NL  LS+ +N++T I GL  L  ++ L LS+N 
Sbjct: 211  LSAYHALTKLILDGNEIEEISGLEMCNNLIHLSLANNKITTINGLNKLP-IKILCLSNNQ 269

Query: 820  IEVIEGLDSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDLX*AQGAQSL 999
            IE+I GL+    L  LD++ N+I  ++ + +   L+   + DN +    ++   +    L
Sbjct: 270  IEMITGLEDLKALQNLDLSHNQISSLQGLENHDLLEVINLEDNKIAELREIEYIKNLPIL 329

Query: 1000 ETVYLERTP 1026
              + L   P
Sbjct: 330  RVLNLLENP 338



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 58/193 (30%), Positives = 99/193 (51%), Gaps = 6/193 (3%)
 Frame = +1

Query: 265 EDVDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENL 444
           + +DL+  +I  +     +  +  L   QN +    N +  ++L++ D   NQI +I +L
Sbjct: 152 QKLDLSANKIEDLSCVSCMPYLLELNASQNNLTTFFNFKPPKNLKKADFSHNQISEICDL 211

Query: 445 EALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRI 624
            A   L  L +  N +  I G++    L  L L NNKI  I  L+ L  +++L L +N+I
Sbjct: 212 SAYHALTKLILDGNEIEEISGLEMCNNLIHLSLANNKITTINGLNKL-PIKILCLSNNQI 270

Query: 625 RAI---ENVDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNR---LTKIEGLQSLV 786
             I   E++  L NL+   L  N+I+ LQ L+    L V++++ N+   L +IE +++L 
Sbjct: 271 EMITGLEDLKALQNLD---LSHNQISSLQGLENHDLLEVINLEDNKIAELREIEYIKNLP 327

Query: 787 NLRELYLSHNGIE 825
            LR L L  N I+
Sbjct: 328 ILRVLNLLENPIQ 340



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 43/137 (31%), Positives = 67/137 (48%), Gaps = 6/137 (4%)
 Frame = +1

Query: 271 VDLNHYRIGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEA 450
           + L + +I  I G   L  +K LCL  N I+ I  LE L++L+ LDL  NQI  ++ LE 
Sbjct: 242 LSLANNKITTINGLNKL-PIKILCLSNNQIEMITGLEDLKALQNLDLSHNQISSLQGLEN 300

Query: 451 LTELEILDISFNL---LRSIEGVDKLTRLKKLFLVNNKINKIEN---LSSLRQLQMLELG 612
              LE++++  N    LR IE +  L  L+ L L+ N I +            L++ EL 
Sbjct: 301 HDLLEVINLEDNKIAELREIEYIKNLPILRVLNLLENPIQEKSEYWFFVIFMLLRLTELD 360

Query: 613 SNRIRAIENVDTLTNLE 663
             +I+  E V  +   +
Sbjct: 361 QKKIKVEEKVSAVNKYD 377


>ref|NP_848547.4| dynein assembly factor 1, axonemal [Homo sapiens].
          Length = 725

 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 61/156 (39%), Positives = 87/156 (55%), Gaps = 7/156 (4%)
 Frame = +1

Query: 367 IENLEALQSLRELDLYDNQIRKIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLV 546
           IENLE    LR L L  N I+KIENLEA TEL  L +  NLLR IE ++ L +L  L L 
Sbjct: 122 IENLEEYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLS 181

Query: 547 NNKINKIENLSSLRQLQMLELGSNRIRAIENVDTL---TNLESLFLGKNKITK---LQNL 708
           NN I  IENLS L  L  L++  N +  +E++  L     L  L L  NK++    L  L
Sbjct: 182 NNYIKTIENLSCLPVLNTLQMAHNHLETVEDIQHLQECLRLCVLDLSHNKLSDPEILSIL 241

Query: 709 DALTNLTVLSMQSNR-LTKIEGLQSLVNLRELYLSH 813
           +++ +L VL++  N  + +I   +  V +R  +L++
Sbjct: 242 ESMPDLRVLNLMGNPVIRQIPNYRRTVTVRLKHLTY 277



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 59/171 (34%), Positives = 91/171 (53%), Gaps = 15/171 (8%)
 Frame = +1

Query: 463 EILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLELGSNRIRAIENV 642
           + L + F     IE +++ T L+ L+L +N I KIENL +  +L+ L L  N +R IEN+
Sbjct: 110 DTLYLHFKGFDRIENLEEYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENL 169

Query: 643 DTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSL---VNLRELYLSH 813
           + L  L++L L  N I  ++NL  L  L  L M  N L  +E +Q L   + L  L LSH
Sbjct: 170 EPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLETVEDIQHLQECLRLCVLDLSH 229

Query: 814 NGI---EVIEGLDSNNKLTMLDIASNR-IKKIEN--------VSHLTELQE 930
           N +   E++  L+S   L +L++  N  I++I N        + HLT L +
Sbjct: 230 NKLSDPEILSILESMPDLRVLNLMGNPVIRQIPNYRRTVTVRLKHLTYLDD 280



 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 49/137 (35%), Positives = 75/137 (54%), Gaps = 6/137 (4%)
 Frame = +1

Query: 430 KIENLEALTELEILDISFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQLQMLEL 609
           +IENLE  T L  L +  N ++ IE ++  T L+ LFL  N + KIENL  L++L  L L
Sbjct: 121 RIENLEEYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNL 180

Query: 610 GSNRIRAIENVDTLTNLESLFLGKN---KITKLQNLDALTNLTVLSMQSNRLTK---IEG 771
            +N I+ IEN+  L  L +L +  N    +  +Q+L     L VL +  N+L+    +  
Sbjct: 181 SNNYIKTIENLSCLPVLNTLQMAHNHLETVEDIQHLQECLRLCVLDLSHNKLSDPEILSI 240

Query: 772 LQSLVNLRELYLSHNGI 822
           L+S+ +LR L L  N +
Sbjct: 241 LESMPDLRVLNLMGNPV 257



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 45/127 (35%), Positives = 74/127 (58%), Gaps = 3/127 (2%)
 Frame = +1

Query: 298 KIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEILDI 477
           +IE  E    ++ L L+ N I+ IENLEA   LR L L  N +RKIENLE L +L+ L++
Sbjct: 121 RIENLEEYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNL 180

Query: 478 SFNLLRSIEGVDKLTRLKKLFLVNNKINKIENLSSLRQ---LQMLELGSNRIRAIENVDT 648
           S N +++IE +  L  L  L + +N +  +E++  L++   L +L+L  N++   E +  
Sbjct: 181 SNNYIKTIENLSCLPVLNTLQMAHNHLETVEDIQHLQECLRLCVLDLSHNKLSDPEILSI 240

Query: 649 LTNLESL 669
           L ++  L
Sbjct: 241 LESMPDL 247



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 50/123 (40%), Positives = 71/123 (57%), Gaps = 7/123 (5%)
 Frame = +1

Query: 292 IGKIEGFEVLRKVKTLCLRQNLIKCIENLEALQSLRELDLYDNQIRKIENLEALTELEIL 471
           I KIE  E   +++ L L+ NL++ IENLE LQ L  L+L +N I+ IENL  L  L  L
Sbjct: 141 IQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTL 200

Query: 472 DISFNLLRSIEGVDKL---TRLKKLFLVNNKINKIENLS---SLRQLQMLEL-GSNRIRA 630
            ++ N L ++E +  L    RL  L L +NK++  E LS   S+  L++L L G+  IR 
Sbjct: 201 QMAHNHLETVEDIQHLQECLRLCVLDLSHNKLSDPEILSILESMPDLRVLNLMGNPVIRQ 260

Query: 631 IEN 639
           I N
Sbjct: 261 IPN 263



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 39/104 (37%), Positives = 60/104 (57%)
 Frame = +1

Query: 661 ESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQSLVNLRELYLSHNGIEVIEGL 840
           ++L+L      +++NL+  T L  L +QSN + KIE L++   LR L+L  N +  IE L
Sbjct: 110 DTLYLHFKGFDRIENLEEYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENL 169

Query: 841 DSNNKLTMLDIASNRIKKIENVSHLTELQEFWMNDNLLESWSDL 972
           +   KL  L++++N IK IEN+S L  L    M  N LE+  D+
Sbjct: 170 EPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLETVEDI 213


  Database: RefSeq49_HP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,297,164
  Number of sequences in database:  32,964
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 32964
Number of Hits to DB: 31,995,845
Number of extensions: 758765
Number of successful extensions: 3432
Number of sequences better than 1.0e-05: 94
Number of HSP's gapped: 3227
Number of HSP's successfully gapped: 174
Length of query: 346
Length of database: 18,297,164
Length adjustment: 103
Effective length of query: 243
Effective length of database: 14,901,872
Effective search space: 3621154896
Effective search space used: 3621154896
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 34 (17.7 bits)

BLASTN 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007857
         (1040 letters)

Database: Sscrofa_10.2.fasta 
           4582 sequences; 2,808,509,378 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Sscrofa_Chr15                                                         325   3e-86

>Sscrofa_Chr15 
||          Length = 157681621

 Score =  325 bits (164), Expect = 3e-86
 Identities = 164/164 (100%)
 Strand = Plus / Plus

                                                                             
Query: 465       gattcttgatatttccttcaatctgctgagaagcatcgaaggggtcgacaagttgacgcg 524
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155040515 gattcttgatatttccttcaatctgctgagaagcatcgaaggggtcgacaagttgacgcg 155040574

                                                                             
Query: 525       gttgaagaaactcttcctggtgaacaacaagataaataaaattgagaacctaagcagcct 584
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155040575 gttgaagaaactcttcctggtgaacaacaagataaataaaattgagaacctaagcagcct 155040634

                                                             
Query: 585       acgtcaactgcagatgctggagctgggatccaaccgcatccggg 628
                 ||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155040635 acgtcaactgcagatgctggagctgggatccaaccgcatccggg 155040678



 Score =  266 bits (134), Expect = 2e-68
 Identities = 134/134 (100%)
 Strand = Plus / Plus

                                                                             
Query: 332       agactctctgtcttcgtcagaatttaattaaatgcattgagaacctggaggcgctgcaga 391
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155040073 agactctctgtcttcgtcagaatttaattaaatgcattgagaacctggaggcgctgcaga 155040132

                                                                             
Query: 392       gccttcgcgagctggacctttacgacaaccagatccggaagatcgagaacctggaggcgc 451
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155040133 gccttcgcgagctggacctttacgacaaccagatccggaagatcgagaacctggaggcgc 155040192

                               
Query: 452       tgacggagctggag 465
                 ||||||||||||||
Sbjct: 155040193 tgacggagctggag 155040206



 Score =  258 bits (130), Expect = 5e-66
 Identities = 130/130 (100%)
 Strand = Plus / Plus

                                                                             
Query: 82        gttgacaggcgggtggagtcggaagagtcgggcgacgaagaagggaagaagcagagcagc 141
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155035241 gttgacaggcgggtggagtcggaagagtcgggcgacgaagaagggaagaagcagagcagc 155035300

                                                                             
Query: 142       gggatagtggccgacctcagcgagcacagcctgaaggatggagaggagcgggggcacgag 201
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155035301 gggatagtggccgacctcagcgagcacagcctgaaggatggagaggagcgggggcacgag 155035360

                           
Query: 202       gagcccgaag 211
                 ||||||||||
Sbjct: 155035361 gagcccgaag 155035370



 Score =  234 bits (118), Expect = 8e-59
 Identities = 118/118 (100%)
 Strand = Plus / Plus

                                                                             
Query: 627       ggcaattgaaaatgtcgacacgttaactaacctggagagtctgtttttggggaaaaacaa 686
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155041665 ggcaattgaaaatgtcgacacgttaactaacctggagagtctgtttttggggaaaaacaa 155041724

                                                                           
Query: 687       gatcacaaaacttcagaacctcgacgcgctcaccaacctgacggtgctcagcatgcag 744
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155041725 gatcacaaaacttcagaacctcgacgcgctcaccaacctgacggtgctcagcatgcag 155041782



 Score =  218 bits (110), Expect = 5e-54
 Identities = 110/110 (100%)
 Strand = Plus / Plus

                                                                             
Query: 740       tgcagagcaaccggctgaccaagatcgagggcctgcagagcctggtgaacctgcgggagc 799
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155042707 tgcagagcaaccggctgaccaagatcgagggcctgcagagcctggtgaacctgcgggagc 155042766

                                                                   
Query: 800       tctacctcagccacaacggcatcgaggtcatcgagggcctggacagcaac 849
                 ||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155042767 tctacctcagccacaacggcatcgaggtcatcgagggcctggacagcaac 155042816



 Score =  172 bits (87), Expect = 2e-40
 Identities = 87/87 (100%)
 Strand = Plus / Plus

                                                                             
Query: 850       aacaagctcaccatgttggacatcgcgtcgaacaggatcaaaaagattgaaaacgtcagc 909
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155045794 aacaagctcaccatgttggacatcgcgtcgaacaggatcaaaaagattgaaaacgtcagc 155045853

                                            
Query: 910       catctaaccgagctgcaggaattctgg 936
                 |||||||||||||||||||||||||||
Sbjct: 155045854 catctaaccgagctgcaggaattctgg 155045880



 Score =  163 bits (82), Expect = 2e-37
 Identities = 82/82 (100%)
 Strand = Plus / Plus

                                                                             
Query: 1         cagattccggaaagggggagagcagcgaacatggcggcggagcgcggcacgggccagcaa 60
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155032397 cagattccggaaagggggagagcagcgaacatggcggcggagcgcggcacgggccagcaa 155032456

                                       
Query: 61        cagtcgcaggagatgatggagg 82
                 ||||||||||||||||||||||
Sbjct: 155032457 cagtcgcaggagatgatggagg 155032478



 Score =  143 bits (72), Expect = 2e-31
 Identities = 101/107 (94%), Gaps = 3/107 (2%)
 Strand = Plus / Plus

                                                                             
Query: 936       gatgaacgacaacctcctggaaagctggagtgacctgnnatgagctca-gggcgcccaga 994
                 ||||||||||||||||||||| |||||||||||||||  ||||||||| ||||||| |||
Sbjct: 155050288 gatgaacgacaacctcctggagagctggagtgacctgg-atgagctcaagggcgccaaga 155050346

                                                                
Query: 995       gcctggagacggtgtacctggagcgg-accccctgcagaaggacccc 1040
                 |||||||||||||||||||||||||| ||||||||||||||||||||
Sbjct: 155050347 gcctggagacggtgtacctggagcggaaccccctgcagaaggacccc 155050393



 Score =  135 bits (68), Expect = 5e-29
 Identities = 68/68 (100%)
 Strand = Plus / Plus

                                                                             
Query: 266       aggatgtggatttgaatcactaccgcattgggaagatcgaaggctttgaggtgctgcgga 325
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155039492 aggatgtggatttgaatcactaccgcattgggaagatcgaaggctttgaggtgctgcgga 155039551

                         
Query: 326       aagtgaag 333
                 ||||||||
Sbjct: 155039552 aagtgaag 155039559



 Score =  117 bits (59), Expect = 1e-23
 Identities = 59/59 (100%)
 Strand = Plus / Plus

                                                                            
Query: 210       agaaggacaagagccgcctgtggatatggaaaccattaacctggaccgagacgcagagg 268
                 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 155038813 agaaggacaagagccgcctgtggatatggaaaccattaacctggaccgagacgcagagg 155038871


  Database: Sscrofa_10.2.fasta
    Posted date:  Nov 16, 2011 10:34 AM
  Number of letters in database: 2,808,509,378
  Number of sequences in database:  4582
  
Lambda     K      H
    1.37    0.711     1.31 

Gapped
Lambda     K      H
    1.37    0.711     1.31 


Matrix: blastn matrix:1 -3
Gap Penalties: Existence: 5, Extension: 2
Number of Sequences: 4582
Number of Hits to DB: 27,193,207
Number of extensions: 166
Number of successful extensions: 166
Number of sequences better than 1.0e-05: 1
Number of HSP's gapped: 162
Number of HSP's successfully gapped: 10
Length of query: 1040
Length of database: 2,808,509,378
Length adjustment: 21
Effective length of query: 1019
Effective length of database: 2,808,413,156
Effective search space: 2861773005964
Effective search space used: 2861773005964
X1: 11 (21.8 bits)
X2: 15 (29.7 bits)
X3: 50 (99.1 bits)
S1: 18 (36.2 bits)
S2: 30 (60.0 bits)