Animal-Genome cDNA 20110601C-007878

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007878
         (1630 letters)

Database: RefSeq49_BP.fasta 
           33,088 sequences; 17,681,374 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_001020516.2| DNA replication licensing factor MCM7 [Bos t...   858   0.0  
Alignment   gi|NP_001068626.1| DNA replication licensing factor MCM4 [Bos t...   182   8e-46
Alignment   gi|NP_001013604.2| DNA replication licensing factor MCM3 [Bos t...   181   2e-45
Alignment   gi|NP_001068758.1| DNA replication licensing factor MCM5 [Bos t...   176   7e-44
Alignment   gi|NP_001039699.1| DNA replication licensing factor MCM6 [Bos t...   164   2e-40
Alignment   gi|XP_002707828.1| PREDICTED: KIAA0030-like [Bos taurus].            148   2e-35
Alignment   gi|XP_869445.4| PREDICTED: minichromosome maintenance complex c...   147   4e-35
Alignment   gi|XP_002692413.1| PREDICTED: minichromosome maintenance comple...   141   1e-33
Alignment   gi|XP_002701121.1| PREDICTED: minichromosome maintenance comple...   141   1e-33
Alignment   gi|NP_001179965.1| DNA replication licensing factor MCM8 [Bos t...   136   6e-32

>ref|NP_001020516.2| DNA replication licensing factor MCM7 [Bos taurus].
          Length = 719

 Score =  858 bits (2217), Expect = 0.0
 Identities = 438/487 (89%), Positives = 448/487 (91%), Gaps = 1/487 (0%)
 Frame = +1

Query: 133  LKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPEL 312
            LKDY LEK+KVKKFLQEFYQDDE GKKQFKYGNQLV+LAHREQVAMY+DLDD+ EDDPEL
Sbjct: 3    LKDYVLEKDKVKKFLQEFYQDDESGKKQFKYGNQLVQLAHREQVAMYVDLDDIAEDDPEL 62

Query: 313  VDSICENTKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP 492
            VDSICENTKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP
Sbjct: 63   VDSICENTKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP 122

Query: 493  QNQYPPELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY 672
            QNQYPPELMRRFELYFQGPSS+KPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY
Sbjct: 123  QNQYPPELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY 182

Query: 673  TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD 852
            TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD
Sbjct: 183  TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD 242

Query: 853  QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR 1032
            QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQ+VQGLLSETYLEAHR
Sbjct: 243  QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQMVQGLLSETYLEAHR 302

Query: 1033 IVKMSKSEDDESGAGELSREELRQIAEEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXX 1212
            IVKMSKSE+DESGAGEL+REELRQI EEDFYEKLAASIAPEIYGHEDVKKA         
Sbjct: 303  IVKMSKSEEDESGAGELTREELRQITEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGV 362

Query: 1213 DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDS 1392
            DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV LTAAVLRDS
Sbjct: 363  DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDS 422

Query: 1393 VSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLH-CPGQHSHTPNGRC 1569
            VSGELTL G  LVL +QGVCCIDEFDKM EADRT I        +         T N RC
Sbjct: 423  VSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARC 482

Query: 1570 SILAAAN 1590
            SILAAAN
Sbjct: 483  SILAAAN 489


>ref|NP_001068626.1| DNA replication licensing factor MCM4 [Bos taurus].
          Length = 836

 Score =  182 bits (462), Expect = 8e-46
 Identities = 146/505 (28%), Positives = 236/505 (46%), Gaps = 26/505 (5%)
 Frame = +1

Query: 154  KEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPELVDSICEN 333
            KE  ++FLQ F   D L K++   G  +    + ++      L+++       ++  CE+
Sbjct: 136  KENFQRFLQRFI--DPLAKEEENVGIDITEPLYMQR------LEEINVTGEPFLNVNCEH 187

Query: 334  TKRY-ARLFADAV---QELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSPQNQ 501
             K +   L+   +   QE++P +     VN+   D Y                       
Sbjct: 188  IKSFDTNLYRQLICYPQEVIPTFDM--AVNEIFFDRY----------------------- 222

Query: 502  YPPELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCD 681
              P+ +   ++  +  ++ K + +R +  + + +L+ + G+V R S++ P M  A + C 
Sbjct: 223  --PDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLIAISGMVIRTSQLIPEMQEAFFQCQ 280

Query: 682  QCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVP 861
             C       I         +C  + C T+ S   ++ +   S F   Q +K+QE  + +P
Sbjct: 281  VCAHTARVEIDRGRIAEPCVC--ERCHTSHSMALIHNR---SVFSDKQMIKLQESPEDMP 335

Query: 862  VGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPI-LRTGFRQVVQGLLSETYLEAHRIV 1038
             G  P ++ +    +     QPGD V VTGI+  + +R   R      + +T+++   ++
Sbjct: 336  AGQTPHTVVLFAHNDLVDKVQPGDRVHVTGIYRAVPIRINPRVSNVKSVYKTHID---VI 392

Query: 1039 KMSKSED------DESGAGELSREELRQIAEE-----DFYEKLAASIAPEIYGHEDVKKA 1185
               K++       DE    +L  E+  ++ +E     D YE+LA+++AP IY HED+KK 
Sbjct: 393  HYRKTDSKRLHGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKG 452

Query: 1186 XXXXXXXXX--DQSPRGM-KIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSS 1356
                       D S  G  K R  INI L GDPG +KSQLL Y+  L PR QYT+G+GSS
Sbjct: 453  ILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVHNLVPRGQYTSGKGSS 512

Query: 1357 GVRLTAAVLRDSVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPI-------TRSWS 1515
             V LTA V++D  + +L L    LVL + GVCCIDEFDKM E+ R+ +       T S +
Sbjct: 513  AVGLTAYVMKDPETRQLVLQTGALVLSDNGVCCIDEFDKMNESTRSVLHEVMEQQTLSIA 572

Query: 1516 TNHLHCPGQHSHTPNGRCSILAAAN 1590
               + C        N R SILAAAN
Sbjct: 573  KAGIIC------QLNARTSILAAAN 591


>ref|NP_001013604.2| DNA replication licensing factor MCM3 [Bos taurus].
          Length = 808

 Score =  181 bits (459), Expect = 2e-45
 Identities = 151/488 (30%), Positives = 232/488 (47%), Gaps = 7/488 (1%)
 Frame = +1

Query: 148  LEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPELVDSIC 327
            +E  + ++   +F  D+E    Q  Y +++  L    Q  + ++++D+            
Sbjct: 10   VELREAQRDYLDFLDDEE---DQGIYQSKVRELISDNQYRLIVNVNDLRR---------- 56

Query: 328  ENTKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSPQNQYP 507
            +N KR  RL ++A +EL                V  +  L     S D   A+    QY 
Sbjct: 57   KNEKRANRLLSNAFEEL----------------VAFQRALKDFVASIDATYAK----QY- 95

Query: 508  PELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQC 687
                  F +  +G   SK    R + +  +  +V V GIVT+ S V+P++V + + C   
Sbjct: 96   ----EEFYIGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPAT 151

Query: 688  GAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRG--SKFIKFQEMKMQEHSDQVP 861
                 +     T   L+  PS      +      L+T    S +   Q + +QE  ++ P
Sbjct: 152  KKTIERRYSDLT--SLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQIITIQEMPEKAP 209

Query: 862  VGNIPRSITVLVEGENTRIAQPGDHVSVTGIF--LPILRTGFRQVVQGLLSETYLEAHRI 1035
             G +PRS+ V+++ +     +PGD V V G +  LP  + G+          T L A  +
Sbjct: 210  AGQLPRSVDVILDDDLVDRVKPGDRVQVVGTYRCLPGKKGGYTSGT----FRTVLIACNV 265

Query: 1036 VKMSKSEDDESGAGELSR-EELRQIAEEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXX 1212
             +MSK       A ++++ ++  +   +D +++LA S+AP I+GH+ VKKA         
Sbjct: 266  KQMSKDVQPSFSAEDIAKIKKFSKTRSKDIFDQLARSLAPSIHGHDYVKKAILCLLLGGV 325

Query: 1213 DQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRD 1389
            ++    G  IRG+INI L+GDP VAKSQLL Y+   APR+  TTGRGSSGV LTAAV  D
Sbjct: 326  ERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTD 385

Query: 1390 SVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLHCPGQHSHTP-NGR 1566
              +GE  L    +VL ++GV CIDEFDKM + DRT I        +       H   N R
Sbjct: 386  QETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNAR 445

Query: 1567 CSILAAAN 1590
            CS+LAAAN
Sbjct: 446  CSVLAAAN 453


>ref|NP_001068758.1| DNA replication licensing factor MCM5 [Bos taurus].
          Length = 734

 Score =  176 bits (445), Expect = 7e-44
 Identities = 138/499 (27%), Positives = 235/499 (47%), Gaps = 20/499 (4%)
 Frame = +1

Query: 154  KEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPELVDSICEN 333
            + + K+FL+++    +     FKY ++L R  +  +  + ++++D+   D EL D + + 
Sbjct: 32   QRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEELADYLYKQ 91

Query: 334  TKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSPQNQYPPE 513
               + +L  +A +E+  +         +VL    + ++M++                   
Sbjct: 92   PAEHLQLLEEAAKEVADEVTRPRPAGDEVLQ---DIQVMLK------------------- 129

Query: 514  LMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGA 693
                        S + P  IR +++D++  LV + GIV   S V+ +    +  C  C +
Sbjct: 130  ------------SDASPSSIRSLKSDTMSHLVKIPGIVIAASGVRAKATRISIQCRSCHS 177

Query: 694  ETYQPIQSPTFMPLIMCPSQECQTNRSG------GRLYLQTRGSKFIKFQEMKMQEHSDQ 855
                    P      +   ++C T+++G         ++     K + FQ +K+QE  D 
Sbjct: 178  TLTNIAMRPGLDGYAL--PRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDA 235

Query: 856  VPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGF-----RQVVQGLLSETYL 1020
            VP G +PR + +  +        PG+ V++ GI+  I + G      R  V   +   Y+
Sbjct: 236  VPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIY-SIKKFGLTSNRGRDRVGVGIRSAYI 294

Query: 1021 EAHRIVKMSKSEDDESG---AGELS---REELRQIAE-EDFYEKLAASIAPEIYGHEDVK 1179
                I    + + D SG   AG ++    EE R++A   + YE ++ SIAP I+G  D+K
Sbjct: 295  RVLGI----QVDTDGSGRTFAGAMTPQEEEEFRRLAALPNIYELISKSIAPSIFGGTDMK 350

Query: 1180 KAXXXXXXXXXDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSS 1356
            KA          +  P G+  RG+IN+ ++GDPG AKSQLL ++++ +P   YT+G+GSS
Sbjct: 351  KAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSS 410

Query: 1357 GVRLTAAVLRDSVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLH-C 1533
               LTA+V+RD  S    + G  +VL + GV CIDEFDKM E DR  I  +     +   
Sbjct: 411  AAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIA 470

Query: 1534 PGQHSHTPNGRCSILAAAN 1590
                + T N RCS+LAAAN
Sbjct: 471  KAGITTTLNSRCSVLAAAN 489


>ref|NP_001039699.1| DNA replication licensing factor MCM6 [Bos taurus].
          Length = 821

 Score =  164 bits (415), Expect = 2e-40
 Identities = 120/405 (29%), Positives = 192/405 (47%), Gaps = 46/405 (11%)
 Frame = +1

Query: 514  LMRRFELYFQG-PSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCG 690
            L + F + FQ  P+  K   IRE+ +  +G L  + G V R   V P +V  T+ C  C 
Sbjct: 106  LAKDFYVAFQDLPTRHK---IRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQ 162

Query: 691  AETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVPVGN 870
                   Q   +    +C +  C   R   R  L T  S+F+ FQ++++QE   ++P G+
Sbjct: 163  TVIKDVEQQFKYTQPNICRNPVCANRR---RFLLDTNKSRFVDFQKVRIQETQAELPRGS 219

Query: 871  IPRSITVLVEGENTRIAQPGDHVSVTGIFLPI------------LRTGFR---------Q 987
            IPRS+ V++  E    AQ GD    TG  + +              T  R         +
Sbjct: 220  IPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETDSRVSGVDGYETE 279

Query: 988  VVQGLLSETYLE-AHRIVKMS-----------------KSEDDESGAGELSREELRQIAE 1113
             V+GL +    + ++R+V ++                 + +  ES   +++ +E  ++ E
Sbjct: 280  GVRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFE 339

Query: 1114 ----EDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXXDQSP-RGMKIRGNINICLMGDPG 1278
                ++ Y  L  S+ P I+G+++VK+           ++   G  +RG+IN+C++GDP 
Sbjct: 340  MSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPS 399

Query: 1279 VAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGELTLGGWRLVLGEQGVCCI 1458
             AKSQ L +++  +PR+ YT+G+ S    LTAAV+RD  S E  +    L+L + GVCCI
Sbjct: 400  TAKSQFLKHVEEFSPRAVYTSGKASIAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCI 459

Query: 1459 DEFDKMGEADRTPITRSWSTNHLH-CPGQHSHTPNGRCSILAAAN 1590
            DEFDKM   D+  I  +     +         T N R SILAAAN
Sbjct: 460  DEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAAN 504


>ref|XP_002707828.1| PREDICTED: KIAA0030-like [Bos taurus].
          Length = 916

 Score =  148 bits (373), Expect = 2e-35
 Identities = 116/369 (31%), Positives = 178/369 (48%), Gaps = 29/369 (7%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 750
            +R +R   + +L+   G+VT  + V P++ +  Y C++CG           F+    C S
Sbjct: 294  LRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCG-----------FVLGPFCQS 342

Query: 751  QECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD--QVPVGNIPRSITVLVEGENTRIA- 921
            Q  Q  + G     Q+ G   +  +E+   + S   +  V NI      L  G+  R A 
Sbjct: 343  QN-QEVKPGSCPECQSAGPFEVNMEEVSASQPSRWFRCFVXNIS-IYRSLANGKIWRTAP 400

Query: 922  ---QPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLE-----------------AHRIVK 1041
               +P     +    LP       +V   L  +T  +                 A+ + K
Sbjct: 401  AAPEPCPQQGLGLSXLPGTCLASHRVTITLQGDTAYDGALNTANGFPVFATVILANHVAK 460

Query: 1042 MSKSEDDESGAGELSREELRQIA----EEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXX 1209
                +D++   GEL+ E+++ I     ++   EK+ ASIAP IYGHED+K+         
Sbjct: 461  ----KDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGG 516

Query: 1210 XDQSPRGM-KIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLR 1386
              ++P G  K+RG+IN+ L GDPG AKSQ L Y+++++ R+ +TTG+G+S V LTA V R
Sbjct: 517  EPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYVEKVSSRAIFTTGQGASAVGLTAYVQR 576

Query: 1387 DSVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLHCPGQHSHTP-NG 1563
              VS E TL    LVL ++GVC IDEFDKM + DRT I  +     +        T    
Sbjct: 577  HPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQA 636

Query: 1564 RCSILAAAN 1590
            RC+++AAAN
Sbjct: 637  RCTVIAAAN 645


>ref|XP_869445.4| PREDICTED: minichromosome maintenance complex component 2 isoform 3
            [Bos taurus].
          Length = 857

 Score =  147 bits (370), Expect = 4e-35
 Identities = 109/346 (31%), Positives = 167/346 (48%), Gaps = 6/346 (1%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 750
            +R +R   + +L+   G+VT  + V P++ +  Y C++CG           F+    C S
Sbjct: 294  LRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCG-----------FVLGPFCQS 342

Query: 751  QECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPG 930
            Q  Q  + G     Q+ G       E+ M+E    +   N   ++       NT    P 
Sbjct: 343  QN-QEVKPGSCPECQSAGPF-----EVNMEEELTGIYHNNYDGAL-------NTANGFP- 388

Query: 931  DHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMSKSEDDESGAGELSREELRQIA 1110
                                    +  T + A+ + K    +D++   GEL+ E+++ I 
Sbjct: 389  ------------------------VFATVILANHVAK----KDNKVAVGELTDEDVKMIT 420

Query: 1111 ----EEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXXDQSPRGM-KIRGNINICLMGDP 1275
                ++   EK+ ASIAP IYGHED+K+           ++P G  K+RG+IN+ L GDP
Sbjct: 421  SLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDP 480

Query: 1276 GVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGELTLGGWRLVLGEQGVCC 1455
            G AKSQ L Y+++++ R+ +TTG+G+S V LTA V R  VS E TL    LVL ++GVC 
Sbjct: 481  GTAKSQFLKYVEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCL 540

Query: 1456 IDEFDKMGEADRTPITRSWSTNHLHCPGQHSHTP-NGRCSILAAAN 1590
            IDEFDKM + DRT I  +     +        T    RC+++AAAN
Sbjct: 541  IDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAAN 586


>ref|XP_002692413.1| PREDICTED: minichromosome maintenance complex component 8 isoform 1
            [Bos taurus].
          Length = 832

 Score =  141 bits (356), Expect = 1e-33
 Identities = 110/362 (30%), Positives = 170/362 (46%), Gaps = 22/362 (6%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 750
            ++ VRA+  GK + +RG V RVS  KP      + C  CG      +    +     CP 
Sbjct: 199  LKNVRANYYGKYIALRGTVVRVSNTKPLCTKMAFLCAACGEIQSLSLPDGKYNLPTKCPV 258

Query: 751  QECQTNRSGGRLYLQTRGSKF---IKFQEMKMQE--HSDQVPVGNIPRSITVLVEGENTR 915
              C+     G+ +   R S     + +Q +K+QE    DQ   G IPR+I   +  +   
Sbjct: 259  PACR-----GKSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVD 313

Query: 916  IAQPGDHVSVTGIF-LPILRTGFRQVVQGLLSETYLEAHRIV----KMSKSEDDESGAGE 1080
               PGD V++TG+  +     G R      +   Y+EA+ +     + +K+ +D    G 
Sbjct: 314  SCVPGDTVTITGVVKVSNAEEGSRNKNDKCMFLLYIEANSVSNNKGQKTKASEDGCKHGA 373

Query: 1081 LSREELRQI-------AEEDFYEKLAASIAPEIYGHEDVKK----AXXXXXXXXXDQSPR 1227
            L    L+ +       +EE+ ++ +  S+ P I+GHE VK     A         D   R
Sbjct: 374  LMEFSLKDLYAIQEIQSEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNR 433

Query: 1228 GMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGEL 1407
             + IRG+ ++ ++GDPG+ KSQ+L  +  +APR  Y  G  ++   LT  + +DS SG+ 
Sbjct: 434  -IPIRGDPHVLVVGDPGLGKSQMLQAVCSVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDF 492

Query: 1408 TLGGWRLVLGEQGVCCIDEFDKMGEADRTPI-TRSWSTNHLHCPGQHSHTPNGRCSILAA 1584
             L    LVLG+QG+C IDEFDKMG   +  +      +  L   G     P  R SI+AA
Sbjct: 493  ALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGMVCSLP-ARTSIIAA 551

Query: 1585 AN 1590
            AN
Sbjct: 552  AN 553


>ref|XP_002701121.1| PREDICTED: minichromosome maintenance complex component 8 [Bos
            taurus].
          Length = 832

 Score =  141 bits (356), Expect = 1e-33
 Identities = 110/362 (30%), Positives = 170/362 (46%), Gaps = 22/362 (6%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 750
            ++ VRA+  GK + +RG V RVS  KP      + C  CG      +    +     CP 
Sbjct: 199  LKNVRANYYGKYIALRGTVVRVSNTKPLCTKMAFLCAACGEIQSLSLPDGKYNLPTKCPV 258

Query: 751  QECQTNRSGGRLYLQTRGSKF---IKFQEMKMQE--HSDQVPVGNIPRSITVLVEGENTR 915
              C+     G+ +   R S     + +Q +K+QE    DQ   G IPR+I   +  +   
Sbjct: 259  PACR-----GKSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVD 313

Query: 916  IAQPGDHVSVTGIF-LPILRTGFRQVVQGLLSETYLEAHRIV----KMSKSEDDESGAGE 1080
               PGD V++TG+  +     G R      +   Y+EA+ +     + +K+ +D    G 
Sbjct: 314  SCVPGDTVTITGVVKVSNAEEGSRNKNDKCMFLLYIEANSVSNNKGQKTKASEDGCKHGA 373

Query: 1081 LSREELRQI-------AEEDFYEKLAASIAPEIYGHEDVKK----AXXXXXXXXXDQSPR 1227
            L    L+ +       +EE+ ++ +  S+ P I+GHE VK     A         D   R
Sbjct: 374  LMEFSLKDLYAIQEIQSEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNR 433

Query: 1228 GMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGEL 1407
             + IRG+ ++ ++GDPG+ KSQ+L  +  +APR  Y  G  ++   LT  + +DS SG+ 
Sbjct: 434  -IPIRGDPHVLVVGDPGLGKSQMLQAVCSVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDF 492

Query: 1408 TLGGWRLVLGEQGVCCIDEFDKMGEADRTPI-TRSWSTNHLHCPGQHSHTPNGRCSILAA 1584
             L    LVLG+QG+C IDEFDKMG   +  +      +  L   G     P  R SI+AA
Sbjct: 493  ALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGMVCSLP-ARTSIIAA 551

Query: 1585 AN 1590
            AN
Sbjct: 552  AN 553


>ref|NP_001179965.1| DNA replication licensing factor MCM8 [Bos taurus].
          Length = 816

 Score =  136 bits (342), Expect = 6e-32
 Identities = 107/357 (29%), Positives = 164/357 (45%), Gaps = 17/357 (4%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 750
            ++ VRA+  GK + +RG V RVS  KP      + C  CG      +    +     CP 
Sbjct: 199  LKNVRANYYGKYIALRGTVVRVSNTKPLCTKMAFLCAACGEIQSLSLPDGKYNLPTKCPV 258

Query: 751  QECQTNRSGGRLYLQTRGSKF---IKFQEMKMQE--HSDQVPVGNIPRSITVLVEGENTR 915
              C+     G+ +   R S     + +Q +K+QE    DQ   G IPR+I   +  +   
Sbjct: 259  PACR-----GKSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVD 313

Query: 916  IAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMSKSEDDESGAGELSREE 1095
               PGD V++TG+           V      E    ++   + +K+ +D    G L    
Sbjct: 314  SCVPGDTVTITGV-----------VKVSNAEEANSVSNNKGQKTKASEDGCKHGALMEFS 362

Query: 1096 LRQI-------AEEDFYEKLAASIAPEIYGHEDVKK----AXXXXXXXXXDQSPRGMKIR 1242
            L+ +       +EE+ ++ +  S+ P I+GHE VK     A         D   R + IR
Sbjct: 363  LKDLYAIQEIQSEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNR-IPIR 421

Query: 1243 GNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGELTLGGW 1422
            G+ ++ ++GDPG+ KSQ+L  +  +APR  Y  G  ++   LT  + +DS SG+  L   
Sbjct: 422  GDPHVLVVGDPGLGKSQMLQAVCSVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAG 481

Query: 1423 RLVLGEQGVCCIDEFDKMGEADRTPI-TRSWSTNHLHCPGQHSHTPNGRCSILAAAN 1590
             LVLG+QG+C IDEFDKMG   +  +      +  L   G     P  R SI+AAAN
Sbjct: 482  ALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGMVCSLP-ARTSIIAAAN 537


  Database: RefSeq49_BP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 17,681,374
  Number of sequences in database:  33,088
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33088
Number of Hits to DB: 66,211,955
Number of extensions: 1954529
Number of successful extensions: 7576
Number of sequences better than 1.0e-05: 13
Number of HSP's gapped: 7546
Number of HSP's successfully gapped: 14
Length of query: 543
Length of database: 17,681,374
Length adjustment: 107
Effective length of query: 436
Effective length of database: 14,140,958
Effective search space: 6165457688
Effective search space used: 6165457688
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007878
         (1630 letters)

Database: RefSeq49_CP.fasta 
           33,336 sequences; 18,874,504 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|XP_849809.1| PREDICTED: similar to DNA replication licensing...   852   0.0  
Alignment   gi|XP_859866.1| PREDICTED: similar to DNA replication licensing...   843   0.0  
Alignment   gi|XP_536865.2| PREDICTED: similar to DNA replication licensing...   843   0.0  
Alignment   gi|XP_859831.1| PREDICTED: similar to DNA replication licensing...   629   e-180
Alignment   gi|XP_541736.2| PREDICTED: similar to minichromosome maintenanc...   182   8e-46
Alignment   gi|XP_538960.2| PREDICTED: similar to DNA replication licensing...   182   1e-45
Alignment   gi|XP_535063.2| PREDICTED: similar to minichromosome maintenanc...   178   1e-44
Alignment   gi|XP_533338.2| PREDICTED: similar to DNA replication licensing...   167   4e-41
Alignment   gi|XP_853134.1| PREDICTED: similar to DNA replication licensing...   157   2e-38
Alignment   gi|XP_860384.1| PREDICTED: similar to minichromosome maintenanc...   145   1e-34

>ref|XP_849809.1| PREDICTED: similar to DNA replication licensing factor MCM7 (CDC47
            homolog) (P1.1-MCM3) isoform 3 [Canis familiaris].
          Length = 719

 Score =  852 bits (2202), Expect = 0.0
 Identities = 437/487 (89%), Positives = 444/487 (91%), Gaps = 1/487 (0%)
 Frame = +1

Query: 133  LKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPEL 312
            +KDY LEKEKVKKFLQEFYQDDE GKKQFKYGNQLV+LAHREQVAMYIDLDDV EDDPEL
Sbjct: 3    VKDYVLEKEKVKKFLQEFYQDDEYGKKQFKYGNQLVQLAHREQVAMYIDLDDVAEDDPEL 62

Query: 313  VDSICENTKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP 492
            VDSICEN +RY RLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP
Sbjct: 63   VDSICENARRYTRLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP 122

Query: 493  QNQYPPELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY 672
            QNQYPPELMRRFELYFQGPSS+KPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY
Sbjct: 123  QNQYPPELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY 182

Query: 673  TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD 852
            TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD
Sbjct: 183  TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD 242

Query: 853  QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR 1032
            QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR
Sbjct: 243  QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR 302

Query: 1033 IVKMSKSEDDESGAGELSREELRQIAEEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXX 1212
            +VKMSKSEDDES A ELSREELRQI EEDFYEKLAASIAPEIYGHEDVKKA         
Sbjct: 303  VVKMSKSEDDESAAVELSREELRQITEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGV 362

Query: 1213 DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDS 1392
            DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV LTAAVLRDS
Sbjct: 363  DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDS 422

Query: 1393 VSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLH-CPGQHSHTPNGRC 1569
            VSGELTL G  LVL +QGVCCIDEFDKM EADRT I        +         T N RC
Sbjct: 423  VSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARC 482

Query: 1570 SILAAAN 1590
            SILAAAN
Sbjct: 483  SILAAAN 489


>ref|XP_859866.1| PREDICTED: similar to DNA replication licensing factor MCM7 (CDC47
            homolog) (P1.1-MCM3) isoform 5 [Canis familiaris].
          Length = 724

 Score =  843 bits (2179), Expect = 0.0
 Identities = 436/492 (88%), Positives = 443/492 (90%), Gaps = 6/492 (1%)
 Frame = +1

Query: 133  LKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPEL 312
            +KDY LEKEKVKKFLQEFYQDDE GKKQFKYGNQLV+LAHREQVAMYIDLDDV EDDPEL
Sbjct: 3    VKDYVLEKEKVKKFLQEFYQDDEYGKKQFKYGNQLVQLAHREQVAMYIDLDDVAEDDPEL 62

Query: 313  VDSICENTKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP 492
            VDSICEN +RY RLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP
Sbjct: 63   VDSICENARRYTRLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP 122

Query: 493  QNQYPPELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY 672
            QNQYPPELMRRFELYFQGPSS+KPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY
Sbjct: 123  QNQYPPELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY 182

Query: 673  TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD 852
            TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD
Sbjct: 183  TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD 242

Query: 853  QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR 1032
            QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR
Sbjct: 243  QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR 302

Query: 1033 IVKMSKSEDDESGAGELSREELRQI-----AEEDFYEKLAASIAPEIYGHEDVKKAXXXX 1197
            +VKMSKSEDDES A ELSREELRQI       EDFYEKLAASIAPEIYGHEDVKKA    
Sbjct: 303  VVKMSKSEDDESAAVELSREELRQITGESPGGEDFYEKLAASIAPEIYGHEDVKKALLLL 362

Query: 1198 XXXXXDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAA 1377
                 DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV LTAA
Sbjct: 363  LVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAA 422

Query: 1378 VLRDSVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLH-CPGQHSHT 1554
            VLRDSVSGELTL G  LVL +QGVCCIDEFDKM EADRT I        +         T
Sbjct: 423  VLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTT 482

Query: 1555 PNGRCSILAAAN 1590
             N RCSILAAAN
Sbjct: 483  LNARCSILAAAN 494


>ref|XP_536865.2| PREDICTED: similar to DNA replication licensing factor MCM7 (CDC47
            homolog) (P1.1-MCM3) isoform 1 [Canis familiaris].
          Length = 733

 Score =  843 bits (2177), Expect = 0.0
 Identities = 437/501 (87%), Positives = 444/501 (88%), Gaps = 15/501 (2%)
 Frame = +1

Query: 133  LKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPEL 312
            +KDY LEKEKVKKFLQEFYQDDE GKKQFKYGNQLV+LAHREQVAMYIDLDDV EDDPEL
Sbjct: 3    VKDYVLEKEKVKKFLQEFYQDDEYGKKQFKYGNQLVQLAHREQVAMYIDLDDVAEDDPEL 62

Query: 313  VDSICENTKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP 492
            VDSICEN +RY RLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP
Sbjct: 63   VDSICENARRYTRLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP 122

Query: 493  QNQYPPELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY 672
            QNQYPPELMRRFELYFQGPSS+KPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY
Sbjct: 123  QNQYPPELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY 182

Query: 673  TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD 852
            TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD
Sbjct: 183  TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD 242

Query: 853  QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR 1032
            QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR
Sbjct: 243  QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR 302

Query: 1033 IVKMSKSEDDESGAGELSREELRQIA--------------EEDFYEKLAASIAPEIYGHE 1170
            +VKMSKSEDDES A ELSREELRQI               EEDFYEKLAASIAPEIYGHE
Sbjct: 303  VVKMSKSEDDESAAVELSREELRQITGESPGGAWEHKLLPEEDFYEKLAASIAPEIYGHE 362

Query: 1171 DVKKAXXXXXXXXXDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRG 1350
            DVKKA         DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRG
Sbjct: 363  DVKKALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRG 422

Query: 1351 SSGVRLTAAVLRDSVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLH 1530
            SSGV LTAAVLRDSVSGELTL G  LVL +QGVCCIDEFDKM EADRT I        + 
Sbjct: 423  SSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTIS 482

Query: 1531 -CPGQHSHTPNGRCSILAAAN 1590
                    T N RCSILAAAN
Sbjct: 483  IAKAGILTTLNARCSILAAAN 503


>ref|XP_859831.1| PREDICTED: similar to DNA replication licensing factor MCM7 (CDC47
            homolog) (P1.1-MCM3) isoform 4 [Canis familiaris].
          Length = 389

 Score =  629 bits (1621), Expect = e-180
 Identities = 314/330 (95%), Positives = 320/330 (96%)
 Frame = +1

Query: 133  LKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPEL 312
            +KDY LEKEKVKKFLQEFYQDDE GKKQFKYGNQLV+LAHREQVAMYIDLDDV EDDPEL
Sbjct: 3    VKDYVLEKEKVKKFLQEFYQDDEYGKKQFKYGNQLVQLAHREQVAMYIDLDDVAEDDPEL 62

Query: 313  VDSICENTKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP 492
            VDSICEN +RY RLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP
Sbjct: 63   VDSICENARRYTRLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP 122

Query: 493  QNQYPPELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY 672
            QNQYPPELMRRFELYFQGPSS+KPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY
Sbjct: 123  QNQYPPELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY 182

Query: 673  TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD 852
            TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD
Sbjct: 183  TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD 242

Query: 853  QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR 1032
            QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR
Sbjct: 243  QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR 302

Query: 1033 IVKMSKSEDDESGAGELSREELRQIAEEDF 1122
            +VKMSKSEDDES A ELSREELRQI +  F
Sbjct: 303  VVKMSKSEDDESAAVELSREELRQITDVIF 332


>ref|XP_541736.2| PREDICTED: similar to minichromosome maintenance protein 2 [Canis
            familiaris].
          Length = 1001

 Score =  182 bits (462), Expect = 8e-46
 Identities = 116/351 (33%), Positives = 182/351 (51%), Gaps = 11/351 (3%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 750
            +R +R   + +L+   G+VT  + V P++ +  Y C++C         S    P     +
Sbjct: 392  LRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKC---------SFVLGPFCQSQN 442

Query: 751  QE-----CQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTR 915
            QE     C   +S G   +    + +  +Q +++QE   +V  G +PRS   ++  +   
Sbjct: 443  QEVKPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVD 502

Query: 916  IAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMSKSEDDESGAGELSREE 1095
              +PGD + +TGI+               +  T + A+ + K    +D++   GEL+ E+
Sbjct: 503  SCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAK----KDNKVAVGELTDED 558

Query: 1096 LRQIA----EEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXXDQSPRGM-KIRGNINIC 1260
            ++ I     ++   EK+ ASIAP IYGHED+K+           ++P G  K+RG+IN+ 
Sbjct: 559  VKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVL 618

Query: 1261 LMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGELTLGGWRLVLGE 1440
            L GDPG AKSQ L YI++++ R+ +TTG+G+S V LTA V R  VS E TL    LVL +
Sbjct: 619  LCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLAD 678

Query: 1441 QGVCCIDEFDKMGEADRTPITRSWSTNHLHCPGQHSHTP-NGRCSILAAAN 1590
            +GVC IDEFDKM + DRT I  +     +        T    RC+I+AAAN
Sbjct: 679  RGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTIIAAAN 729


>ref|XP_538960.2| PREDICTED: similar to DNA replication licensing factor MCM3 (DNA
            polymerase alpha holoenzyme-associated protein P1) (RLF
            beta subunit) (P102 protein) (P1-MCM3) [Canis
            familiaris].
          Length = 916

 Score =  182 bits (461), Expect = 1e-45
 Identities = 151/488 (30%), Positives = 232/488 (47%), Gaps = 7/488 (1%)
 Frame = +1

Query: 148  LEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPELVDSIC 327
            +E  + ++   +F  D+E    Q  Y +++  L    Q  + ++++D+            
Sbjct: 118  VELREAQRDYLDFLDDEE---DQGIYQSKVRELISDNQYRLIVNVNDLRR---------- 164

Query: 328  ENTKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSPQNQYP 507
            +N KR  RL ++A +EL                V  +  L     S D   A+    QY 
Sbjct: 165  KNEKRANRLLSNAFEEL----------------VAFQRALKDFVASIDATYAK----QY- 203

Query: 508  PELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQC 687
                  F +  +G   SK    R + +  +  +V V GIVT+ S V+P++V + + C   
Sbjct: 204  ----EEFYIGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPAT 259

Query: 688  GAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRG--SKFIKFQEMKMQEHSDQVP 861
                 +     T   L+  PS      +      L+T    S +   Q + +QE  ++ P
Sbjct: 260  KKTIERRYSDLT--TLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAP 317

Query: 862  VGNIPRSITVLVEGENTRIAQPGDHVSVTGIF--LPILRTGFRQVVQGLLSETYLEAHRI 1035
             G +PRS+ V+++ +     +PGD V V G +  LP  + G+          T L A  +
Sbjct: 318  AGQLPRSVDVILDDDLVDKVKPGDRVQVVGTYRCLPGKKGGYTSGT----FRTILIACNV 373

Query: 1036 VKMSKSEDDESGAGELSR-EELRQIAEEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXX 1212
             +MSK       A ++++ ++  +   +D +++LA S+AP I+GH+ VKKA         
Sbjct: 374  KQMSKDVQPSFSAEDIAKIKKFSKTRSKDIFDQLARSLAPSIHGHDYVKKAILCLLLGGV 433

Query: 1213 DQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRD 1389
            ++    G  IRG+INI L+GDP VAKSQLL Y+   APR+  TTGRGSSGV LTAAV  D
Sbjct: 434  ERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTD 493

Query: 1390 SVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLHCPGQHSHTP-NGR 1566
              +GE  L    +VL ++GV CIDEFDKM + DRT I        +       H   N R
Sbjct: 494  QETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNAR 553

Query: 1567 CSILAAAN 1590
            CS+LAAAN
Sbjct: 554  CSVLAAAN 561


>ref|XP_535063.2| PREDICTED: similar to minichromosome maintenance protein 4 [Canis
            familiaris].
          Length = 929

 Score =  178 bits (452), Expect = 1e-44
 Identities = 124/384 (32%), Positives = 192/384 (50%), Gaps = 19/384 (4%)
 Frame = +1

Query: 496  NQYPPELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYT 675
            ++YP  ++   ++  +  ++ K + +R +  D + +L+ + G+V R S++ P M  A + 
Sbjct: 313  DRYPDSILEH-QIQVRPFNALKTKNMRNLNPDDIDQLIAISGMVIRTSQLIPEMQEAFFQ 371

Query: 676  CDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQ 855
            C  C       I         +C  + C T  S   ++ +   S F   Q +K+QE  + 
Sbjct: 372  CQVCAHTARVEIDRGRIAEPSVC--EHCHTTHSMALIHNR---SVFSDKQMIKLQESPED 426

Query: 856  VPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPI-LRTGFRQVVQGLLSETYLEAHR 1032
            +P G  P ++ +    +     QPGD V++TGI+  + +R   R      + +T+++   
Sbjct: 427  MPAGQTPHTVILFAHNDLVDKVQPGDRVNITGIYRAVPIRVSSRVSNVKSVYKTHIDVIH 486

Query: 1033 IVKMSKSED---DESGAGELSREELRQIAEE-----DFYEKLAASIAPEIYGHEDVKKAX 1188
              K         DE    +L  E+  ++ +E     D YE+LA+++AP IY HED+KK  
Sbjct: 487  YRKTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGI 546

Query: 1189 XXXXXXXX--DQSPRGM-KIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSG 1359
                      D S  G  K R  INI L GDPG +KSQLL Y+  L PR QYT+G+GSS 
Sbjct: 547  LLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 606

Query: 1360 VRLTAAVLRDSVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPI-------TRSWST 1518
            V LTA V++D  + +L L    LVL + G+CCIDEFDKM E+ R+ +       T S + 
Sbjct: 607  VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAK 666

Query: 1519 NHLHCPGQHSHTPNGRCSILAAAN 1590
              + C        N R SILAAAN
Sbjct: 667  AGIIC------QLNARTSILAAAN 684


>ref|XP_533338.2| PREDICTED: similar to DNA replication licensing factor MCM6 (P105MCM)
            [Canis familiaris].
          Length = 955

 Score =  167 bits (422), Expect = 4e-41
 Identities = 119/406 (29%), Positives = 190/406 (46%), Gaps = 47/406 (11%)
 Frame = +1

Query: 514  LMRRFELYFQG-PSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCG 690
            L + F + FQ  P+  K   IRE+ +  +G L  + G V R   V P +V  T+ C  C 
Sbjct: 240  LAKDFYVAFQDLPTRHK---IRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQ 296

Query: 691  AETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVPVGN 870
                   Q   +    +C +  C   R   R  L T  S+F+ FQ++++QE   ++P G+
Sbjct: 297  TVIKDVEQQFKYTQPNICRNPVCANRR---RFLLDTNKSRFVDFQKVRIQETQAELPRGS 353

Query: 871  IPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLE--------- 1023
            IPRS+ V++  E    AQ GD    TG  + +     +  + G  +ET            
Sbjct: 354  IPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVS-KLSIPGARAETNSRVSGVDGYET 412

Query: 1024 --------------AHRIVKMS-----------------KSEDDESGAGELSREELRQIA 1110
                          ++R+V ++                 + +  ES   +++ +E  ++ 
Sbjct: 413  EGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVF 472

Query: 1111 E----EDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXXDQSP-RGMKIRGNINICLMGDP 1275
            E    ++ Y  L  S+ P I+G+++VK+           ++   G  +RG+IN+C++GDP
Sbjct: 473  EMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDP 532

Query: 1276 GVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGELTLGGWRLVLGEQGVCC 1455
              AKSQ L +++  +PR+ YT+G+ SS   LTAAV+RD  S E  +    L+L + GVCC
Sbjct: 533  STAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCC 592

Query: 1456 IDEFDKMGEADRTPITRSWSTNHLH-CPGQHSHTPNGRCSILAAAN 1590
            IDEFDKM   D+  I  +     +         T N R SILAAAN
Sbjct: 593  IDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAAN 638


>ref|XP_853134.1| PREDICTED: similar to DNA replication licensing factor MCM5 (CDC46
            homolog) (P1-CDC46) [Canis familiaris].
          Length = 634

 Score =  157 bits (398), Expect = 2e-38
 Identities = 114/362 (31%), Positives = 181/362 (50%), Gaps = 17/362 (4%)
 Frame = +1

Query: 556  SKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPL 735
            ++P +   V++D +  LV + GI+   S V+ +    +  C  C          P     
Sbjct: 32   NQPLLGGSVQSDMMSHLVKIPGIIISASGVRAKATRISIQCRSCRNTLSNIAMRPGLEGY 91

Query: 736  IMCPSQECQTNRSG------GRLYLQTRGSKFIKFQEMKMQEHSDQVPVGNIPRSITVLV 897
             +   ++C T+++G         ++     K + FQ +K+QE  D VP G +PR + +  
Sbjct: 92   AL--PRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYC 149

Query: 898  EGENTRIAQPGDHVSVTGIFLPILRTGF-----RQVVQGLLSETYLEAHRIVKMSKSEDD 1062
            +        PG+ V++ GI+  I + G      R  V   +  +Y+    I ++      
Sbjct: 150  DRYLCDKVVPGNRVTIMGIY-SIKKFGLTTSKGRDRVGVGIRSSYIRVLGI-QVDTDGSG 207

Query: 1063 ESGAGELS---REELRQIAE-EDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXXDQS-PR 1227
             S AG ++    EE R++A   + YE ++ SIAP I+G  D+KKA          +  P 
Sbjct: 208  RSFAGAVTPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPD 267

Query: 1228 GMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGEL 1407
            G+  RG+IN+ ++GDPG AKSQLL ++++ +P   YT+G+GSS   LTA+V+RD  S   
Sbjct: 268  GLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNF 327

Query: 1408 TLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLH-CPGQHSHTPNGRCSILAA 1584
             + G  +VL + GV CIDEFDKM E DR  I  +     +       + T N RCS+LAA
Sbjct: 328  IMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAA 387

Query: 1585 AN 1590
            AN
Sbjct: 388  AN 389


>ref|XP_860384.1| PREDICTED: similar to minichromosome maintenance protein 8 isoform 1
            isoform 4 [Canis familiaris].
          Length = 805

 Score =  145 bits (366), Expect = 1e-34
 Identities = 112/362 (30%), Positives = 171/362 (47%), Gaps = 22/362 (6%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 750
            ++ VRA+  GK + +RG V RVS +KP      + C  CG      +    +     CP 
Sbjct: 172  LKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEVQSFSLPDGKYNLPTKCPV 231

Query: 751  QECQTNRSGGRLYLQTRGSKF---IKFQEMKMQE--HSDQVPVGNIPRSITVLVEGENTR 915
              C+     GR +   R S     + +Q +K+QE    DQ   G IPR+I   +  +   
Sbjct: 232  PTCR-----GRSFTALRNSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVD 286

Query: 916  IAQPGDHVSVTGIF-LPILRTGFRQVVQGLLSETYLEAHRIV----KMSKSEDDESGAGE 1080
               PGD V++TG+  +     G R      +   Y+EA+ +     + +K+ +D    G 
Sbjct: 287  SCVPGDTVTITGVVKVSNAEEGSRNKNDKCMFLLYIEANSVSNSKGQKTKTSEDGCKHGA 346

Query: 1081 LSREELRQI-------AEEDFYEKLAASIAPEIYGHEDVKK----AXXXXXXXXXDQSPR 1227
            L    L+ +       AEE+ ++ +  S+ P I+GHE VK     A         D   R
Sbjct: 347  LMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNR 406

Query: 1228 GMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGEL 1407
             + IRG+ ++ ++GDPG+ KSQ+L  +  +APR  Y  G  ++   LT  + +DS SG+ 
Sbjct: 407  -IPIRGDPHVLVVGDPGLGKSQMLQAVCNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDF 465

Query: 1408 TLGGWRLVLGEQGVCCIDEFDKMGEADRTPI-TRSWSTNHLHCPGQHSHTPNGRCSILAA 1584
             L    LVLG+QG+C IDEFDKMG   +  +      +  L   G     P  R SI+AA
Sbjct: 466  ALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGMVCSLP-ARTSIIAA 524

Query: 1585 AN 1590
            AN
Sbjct: 525  AN 526


  Database: RefSeq49_CP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,874,504
  Number of sequences in database:  33,336
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33336
Number of Hits to DB: 69,230,733
Number of extensions: 2026582
Number of successful extensions: 7751
Number of sequences better than 1.0e-05: 13
Number of HSP's gapped: 7710
Number of HSP's successfully gapped: 14
Length of query: 543
Length of database: 18,874,504
Length adjustment: 108
Effective length of query: 435
Effective length of database: 15,274,216
Effective search space: 6644283960
Effective search space used: 6644283960
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007878
         (1630 letters)

Database: RefSeq49_SP.fasta 
           24,897 sequences; 11,343,932 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|XP_003354515.1| PREDICTED: DNA replication licensing factor ...   271   6e-73
Alignment   gi|XP_003358597.1| PREDICTED: DNA replication licensing factor ...   184   2e-46
Alignment   gi|XP_001924848.1| PREDICTED: DNA replication licensing factor ...   179   3e-45
Alignment   gi|XP_001927529.3| PREDICTED: DNA replication licensing factor ...   140   3e-33
Alignment   gi|XP_003353280.1| PREDICTED: DNA replication licensing factor ...   100   2e-21

>ref|XP_003354515.1| PREDICTED: DNA replication licensing factor MCM7-like [Sus scrofa].
          Length = 255

 Score =  271 bits (694), Expect = 6e-73
 Identities = 147/184 (79%), Positives = 149/184 (80%), Gaps = 1/184 (0%)
 Frame = +1

Query: 1042 MSKSEDDESGAGELSREELRQIAEEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXXDQS 1221
            MSKSEDDESGAGELSREELRQIAEEDFYEKLAASIAPEIYGHEDVKKA         DQS
Sbjct: 1    MSKSEDDESGAGELSREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS 60

Query: 1222 PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSG 1401
            PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV LTAAVLRDSVSG
Sbjct: 61   PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSG 120

Query: 1402 ELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLH-CPGQHSHTPNGRCSIL 1578
            ELTL G  LVL +QGVCCIDEFDKM EADRT I        +         T N RCSIL
Sbjct: 121  ELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSIL 180

Query: 1579 AAAN 1590
            AAAN
Sbjct: 181  AAAN 184


>ref|XP_003358597.1| PREDICTED: DNA replication licensing factor MCM2 [Sus scrofa].
          Length = 596

 Score =  184 bits (466), Expect = 2e-46
 Identities = 118/348 (33%), Positives = 185/348 (53%), Gaps = 8/348 (2%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCG--AETYQPIQSPTFMPLIMC 744
            +R +R   + +L+   G+VT  + V P++ +  Y C++CG     +   Q+    P   C
Sbjct: 73   LRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCGFVLGPFCQSQNQEVKPG-SC 131

Query: 745  PSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQ 924
            P  ECQ   S G   +    + +  +Q +++QE   +V  G +PRS   ++  +     +
Sbjct: 132  P--ECQ---SAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCK 186

Query: 925  PGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMSKSEDDESGAGELSREELRQ 1104
            PGD + +TGI+               +  T + A+ + K    +D++   GEL+ E+++ 
Sbjct: 187  PGDEIELTGIYHNNYDGALNTANGFPVFATVILANHVAK----KDNKVAVGELTDEDVKM 242

Query: 1105 IA----EEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXXDQSPRGM-KIRGNINICLMG 1269
            I     ++   EK+ ASIAP IYGHED+K+           ++P G  K+RG+IN+ L G
Sbjct: 243  ITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCG 302

Query: 1270 DPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGELTLGGWRLVLGEQGV 1449
            DPG AKSQ L YI++++ R+ +TTG+G+S V LTA V R  VS E TL    LVL ++GV
Sbjct: 303  DPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGV 362

Query: 1450 CCIDEFDKMGEADRTPITRSWSTNHLHCPGQHSHTP-NGRCSILAAAN 1590
            C IDEFDKM + DRT I  +     +        T    RC+++AAAN
Sbjct: 363  CLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAAN 410


>ref|XP_001924848.1| PREDICTED: DNA replication licensing factor MCM3 [Sus scrofa].
          Length = 808

 Score =  179 bits (455), Expect = 3e-45
 Identities = 124/360 (34%), Positives = 184/360 (51%), Gaps = 5/360 (1%)
 Frame = +1

Query: 526  FELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQ 705
            F +  +G   SK    R + +  +  +V V GIVT+ S V+P++V + + C        +
Sbjct: 98   FYIGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIER 157

Query: 706  PIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVPVGNIPRSI 885
                 T +      S     +     L  +   S +   Q + +QE  ++ P G +PRS+
Sbjct: 158  RYTDLTTLEAFPSSSVYPTKDEENNPLETEYGLSVYKDHQIITIQEMPEKAPAGQLPRSV 217

Query: 886  TVLVEGENTRIAQPGDHVSVTGIF--LPILRTGFRQVVQGLLSETYLEAHRIVKMSKSED 1059
             V+++ +     +PGD V V G +  LP  + G+          T L A  + +MSK   
Sbjct: 218  DVILDDDLVDKVKPGDRVQVVGTYRCLPGKKGGYTSGT----FRTVLIACNVKQMSKDAQ 273

Query: 1060 DESGAGELSR-EELRQIAEEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXXDQS-PRGM 1233
                A ++++ ++  +   +D +++LA S+AP I+GH+ VKKA         ++    G 
Sbjct: 274  PSFSAEDIAKIKKFSKTRSKDIFDQLARSLAPSIHGHDYVKKAILCLLLGGVERDLENGS 333

Query: 1234 KIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGELTL 1413
             IRG+INI L+GDP VAKSQLL Y+   APR+  TTGRGSSGV LTAAV  D  +GE  L
Sbjct: 334  HIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRL 393

Query: 1414 GGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLHCPGQHSHTP-NGRCSILAAAN 1590
                +VL ++GV CIDEFDKM + DRT I        +       H   N RCS+LAAAN
Sbjct: 394  EAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAAN 453


>ref|XP_001927529.3| PREDICTED: DNA replication licensing factor MCM8 [Sus scrofa].
          Length = 837

 Score =  140 bits (352), Expect = 3e-33
 Identities = 111/362 (30%), Positives = 169/362 (46%), Gaps = 22/362 (6%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 750
            ++ VRA+  GK +++RG V RVS +KP      + C  CG      +    +     CP 
Sbjct: 204  LKNVRANYYGKYISLRGTVVRVSNIKPLCTKMAFLCATCGEIQSFSLPDGKYNLPTKCPI 263

Query: 751  QECQTNRSGGRLYLQTRGSKFI---KFQEMKMQE--HSDQVPVGNIPRSITVLVEGENTR 915
              C+     G+ +   R S       +Q +K+QE    DQ   G IPR+I   +  +   
Sbjct: 264  PACR-----GKSFTALRSSPLTVTTDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVD 318

Query: 916  IAQPGDHVSVTGIF-LPILRTGFRQVVQGLLSETYLEAHRIVKM----SKSEDDESGAGE 1080
               PGD V++TG+  +     G R      +   Y+EA+ +       +K+ +D    G 
Sbjct: 319  SCVPGDTVTITGVVKVSNAEEGSRNKNDKCMFLLYVEANSVSNSKGQNTKTSEDGYKPGT 378

Query: 1081 LSREELRQI-------AEEDFYEKLAASIAPEIYGHEDVKK----AXXXXXXXXXDQSPR 1227
            L    L+ +       +EE+ ++ +  S+ P I+GHE VK     A         D   R
Sbjct: 379  LMEFSLKDLYAIQEIQSEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNR 438

Query: 1228 GMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGEL 1407
             + IRG+ +I ++GDPG+ KSQ+L     +APR  Y  G  ++   LT  + +DS SG+ 
Sbjct: 439  -IPIRGDPHILVVGDPGLGKSQMLQAACSVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDF 497

Query: 1408 TLGGWRLVLGEQGVCCIDEFDKMGEADRTPI-TRSWSTNHLHCPGQHSHTPNGRCSILAA 1584
             L    LVLG+QG+C IDEFDKMG   +  +      +  L   G     P  R SI+AA
Sbjct: 498  ALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGMVCSLP-ARTSIIAA 556

Query: 1585 AN 1590
            AN
Sbjct: 557  AN 558


>ref|XP_003353280.1| PREDICTED: DNA replication licensing factor MCM9 [Sus scrofa].
          Length = 391

 Score =  100 bits (249), Expect = 2e-21
 Identities = 88/297 (29%), Positives = 146/297 (49%), Gaps = 18/297 (6%)
 Frame = +1

Query: 562  PRVIRE--VRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPI---QSPTF 726
            P ++RE   +   VG  ++V G V R S VK       Y C++C           Q  TF
Sbjct: 107  PELVREHIPKTKDVGHFLSVTGTVIRTSLVKILEFERDYMCNKCKHVFVVKADFEQYYTF 166

Query: 727  MPLIMCPSQE-CQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVPVGNIPRSITVLVEG 903
                 CPS E C + +      L +  ++   +QE+K+QE   ++ VG+IPRS+ V++E 
Sbjct: 167  CRPSSCPSLESCGSTKFTCLSDLSSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMKVILED 226

Query: 904  ENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMSKSEDDESGAGEL 1083
            +     + GD +++ G+ +   +  F+Q V+  + E  L+A+ +       ++E   G  
Sbjct: 227  DLVDSCKSGDDLTIYGVVMQRWKP-FQQDVRCEV-EIVLKANYV-----QVNNEQSTGIN 279

Query: 1084 SREELRQIAEEDFYE-----------KLAASIAPEIYGHEDVKKAXXXXXXXXXDQSPR- 1227
              EE+R+   EDF+E           ++ AS+ P++YG   VK A          ++   
Sbjct: 280  MDEEVRK-EFEDFWEYYKSDPFAGRNEILASLCPQVYGMYLVKLAVAMVLAGGIQRTDAT 338

Query: 1228 GMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVS 1398
            G ++RG  ++ L+GDPG  KSQ L Y  ++ PRS  TTG GS+    +A +L D+ S
Sbjct: 339  GTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGST----SAGILCDNFS 391


  Database: RefSeq49_SP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 11,343,932
  Number of sequences in database:  24,897
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 24897
Number of Hits to DB: 42,733,961
Number of extensions: 1258728
Number of successful extensions: 4771
Number of sequences better than 1.0e-05: 5
Number of HSP's gapped: 4754
Number of HSP's successfully gapped: 5
Length of query: 543
Length of database: 11,343,932
Length adjustment: 104
Effective length of query: 439
Effective length of database: 8,754,644
Effective search space: 3843288716
Effective search space used: 3843288716
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007878
         (1630 letters)

Database: RefSeq49_MP.fasta 
           30,036 sequences; 15,617,559 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_032594.1| DNA replication licensing factor MCM7 [Mus musc...   818   0.0  
Alignment   gi|NP_032591.3| DNA replication licensing factor MCM4 [Mus musc...   183   3e-46
Alignment   gi|NP_032590.2| DNA replication licensing factor MCM2 [Mus musc...   181   1e-45
Alignment   gi|NP_032589.1| DNA replication licensing factor MCM3 [Mus musc...   181   2e-45
Alignment   gi|NP_032592.2| DNA replication licensing factor MCM5 [Mus musc...   171   1e-42
Alignment   gi|NP_032593.1| DNA replication licensing factor MCM6 [Mus musc...   167   3e-41
Alignment   gi|NP_079952.2| DNA replication licensing factor MCM8 [Mus musc...   141   2e-33
Alignment   gi|NP_082106.2| DNA replication licensing factor MCM9 [Mus musc...   138   1e-32

>ref|NP_032594.1| DNA replication licensing factor MCM7 [Mus musculus].
          Length = 719

 Score =  818 bits (2114), Expect = 0.0
 Identities = 413/487 (84%), Positives = 439/487 (90%), Gaps = 1/487 (0%)
 Frame = +1

Query: 133  LKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPEL 312
            LKDYA+EKEKVKKFLQEFY ++ELGKKQFKYG QLV LAHREQVA+Y+DLDD+ EDDPEL
Sbjct: 3    LKDYAIEKEKVKKFLQEFYYENELGKKQFKYGTQLVHLAHREQVALYVDLDDIAEDDPEL 62

Query: 313  VDSICENTKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP 492
            VDSICEN KRY+RLF D VQELLP+YKE+EVVNKDVLDVYIEHRLMMEQRSRDPGA R+P
Sbjct: 63   VDSICENAKRYSRLFGDVVQELLPEYKEKEVVNKDVLDVYIEHRLMMEQRSRDPGAVRNP 122

Query: 493  QNQYPPELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY 672
            QNQYP ELMRRFELYF+GPSSSKPRVIREVRADSVGKL+TVRGIVTRVSEVKPRMVVATY
Sbjct: 123  QNQYPSELMRRFELYFRGPSSSKPRVIREVRADSVGKLLTVRGIVTRVSEVKPRMVVATY 182

Query: 673  TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD 852
            TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKF+KFQEMK+QEHSD
Sbjct: 183  TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFVKFQEMKIQEHSD 242

Query: 853  QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR 1032
            QVPVGNIPRSITV++EGENTRIAQPGDHVSVTGIFLP+LRTGF+Q+ QGLLSETYLEAH 
Sbjct: 243  QVPVGNIPRSITVVLEGENTRIAQPGDHVSVTGIFLPVLRTGFQQMAQGLLSETYLEAHW 302

Query: 1033 IVKMSKSEDDESGAGELSREELRQIAEEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXX 1212
            IVKM+KS+DD SGAGELS EEL+QIAEEDFYEKLAASIAPEIYGHEDVKKA         
Sbjct: 303  IVKMTKSDDDVSGAGELSSEELKQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGV 362

Query: 1213 DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDS 1392
            DQSP+GMKIRGNI+ICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV LTAAVLRDS
Sbjct: 363  DQSPQGMKIRGNIHICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDS 422

Query: 1393 VSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLH-CPGQHSHTPNGRC 1569
            VSGELTL G  LVL +QGVCCIDEFDKM EADRT I        +         T N RC
Sbjct: 423  VSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARC 482

Query: 1570 SILAAAN 1590
            SILAAAN
Sbjct: 483  SILAAAN 489


>ref|NP_032591.3| DNA replication licensing factor MCM4 [Mus musculus].
          Length = 862

 Score =  183 bits (465), Expect = 3e-46
 Identities = 147/502 (29%), Positives = 234/502 (46%), Gaps = 23/502 (4%)
 Frame = +1

Query: 154  KEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPELVDSICEN 333
            KE  ++FLQ F   D L K++   G  + +  + +Q      L ++       ++  CE+
Sbjct: 162  KENFQRFLQCF--TDPLAKEEENVGIDITQPLYMQQ------LGEINITGEPFLNVNCEH 213

Query: 334  TKRYAR-LFADAV---QELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSPQNQ 501
             K +++ L+   +   QE++P +     VN+   D Y                       
Sbjct: 214  IKSFSKNLYRQLISYPQEVIPTFDM--AVNEIFFDRY----------------------- 248

Query: 502  YPPELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCD 681
              P+ +   ++  +  ++ K + +R +  + + +L+T+ G+V R S++ P M  A + C 
Sbjct: 249  --PDSILEHQIQVRPFNALKTKSMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQ 306

Query: 682  QCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVP 861
             C   T   I          C    C T  S   ++ +   S F   Q +K+QE  + +P
Sbjct: 307  VCAHTTRVEIDRGRIAE--PCSCVHCHTTHSMALIHNR---SFFSDKQMIKLQESPEDMP 361

Query: 862  VGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPI-LRTGFRQVVQGLLSETYLEAHRIV 1038
             G  P +I +    +     QPGD V+VTGI+  + +R   R      + +T+++     
Sbjct: 362  AGQTPHTIVLFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYR 421

Query: 1039 KMSKSE----DDESGAGELSREELRQIAE----EDFYEKLAASIAPEIYGHEDVKKAXXX 1194
            K         D+E+     S + ++ + E     D YE+LA+++AP IY HED+KK    
Sbjct: 422  KTDAKRLHGLDEEAEQKLFSEKRVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILL 481

Query: 1195 XXXXXX--DQSPRGM-KIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVR 1365
                    D S  G  K R  INI L GDPG +KSQLL Y+  L PR QYT+G+GSS V 
Sbjct: 482  QLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVG 541

Query: 1366 LTAAVLRDSVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPI-------TRSWSTNH 1524
            LTA V++D  + +L L    LVL + G+CCIDEFDKM E+ R+ +       T S +   
Sbjct: 542  LTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAG 601

Query: 1525 LHCPGQHSHTPNGRCSILAAAN 1590
            + C        N R S+LAAAN
Sbjct: 602  IIC------QLNARTSVLAAAN 617


>ref|NP_032590.2| DNA replication licensing factor MCM2 [Mus musculus].
          Length = 904

 Score =  181 bits (460), Expect = 1e-45
 Identities = 117/348 (33%), Positives = 183/348 (52%), Gaps = 8/348 (2%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCG--AETYQPIQSPTFMPLIMC 744
            +R +R   + +L+   G+VT  + V P++ +  Y C +C      +   Q+    P   C
Sbjct: 294  LRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCSKCNFVLGPFCQSQNQEVKPG-SC 352

Query: 745  PSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQ 924
            P  ECQ   S G   +    + +  +Q +++QE   +V  G +PRS   ++  +     +
Sbjct: 353  P--ECQ---SAGPFEINMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCK 407

Query: 925  PGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMSKSEDDESGAGELSREELRQ 1104
            PGD + +TGI+               +  T + A+ + K    +D++   GEL+ E+++ 
Sbjct: 408  PGDEIELTGIYHNNYDGSLNTANGFPVFATIILANHVAK----KDNKVAVGELTDEDVKM 463

Query: 1105 IA----EEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXXDQSPRGM-KIRGNINICLMG 1269
            I     ++   EK+ ASIAP IYGHED+K+           ++P G  K+RG+IN+ L G
Sbjct: 464  ITGLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCG 523

Query: 1270 DPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGELTLGGWRLVLGEQGV 1449
            DPG AKSQ L YI++++ R+ +TTG+G+S V LTA V R  VS E TL    LVL ++GV
Sbjct: 524  DPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGV 583

Query: 1450 CCIDEFDKMGEADRTPITRSWSTNHLHCPGQHSHTP-NGRCSILAAAN 1590
            C IDEFDKM + DRT I  +     +        T    RC+++AAAN
Sbjct: 584  CLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAAN 631


>ref|NP_032589.1| DNA replication licensing factor MCM3 [Mus musculus].
          Length = 812

 Score =  181 bits (458), Expect = 2e-45
 Identities = 150/486 (30%), Positives = 228/486 (46%), Gaps = 5/486 (1%)
 Frame = +1

Query: 148  LEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPELVDSIC 327
            +E  + ++   +F  D+E    Q  Y N++  L    Q  + + ++D+            
Sbjct: 10   VELREAQRDYLDFLDDEE---DQGIYQNKVRELISDNQYRLIVSVNDLRR---------- 56

Query: 328  ENTKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSPQNQYP 507
            +N KR  RL  +A +EL                V  +  L     S D   A+    QY 
Sbjct: 57   KNEKRANRLLNNAFEEL----------------VAFQRALKDFVASIDATYAK----QY- 95

Query: 508  PELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQC 687
                  F +  +G   SK    R + +  +  +V V GIVT+ S V+P++V + + C   
Sbjct: 96   ----EEFYIGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPAT 151

Query: 688  GAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRG--SKFIKFQEMKMQEHSDQVP 861
                 +     T   L+  PS      +      L+T    S +   Q + +QE  ++ P
Sbjct: 152  KKTIERRYSDLT--TLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAP 209

Query: 862  VGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVK 1041
             G +PRS+ V+++ +     +PGD + V G +  +   G +         T L A  + +
Sbjct: 210  AGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYRCL--PGKKGCYTSGTFRTVLIACNVKQ 267

Query: 1042 MSKSEDDESGAGELSR-EELRQIAEEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXXDQ 1218
            MSK       A ++++ ++  +   +D +E+LA S+AP I+GH+ VKKA         ++
Sbjct: 268  MSKDIQPAFSADDIAKIKKFSKTRSKDVFEQLARSLAPSIHGHDYVKKAILCLLLGGVER 327

Query: 1219 S-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSV 1395
                G  IRG+INI L+GDP VAKSQLL Y+   APR+  TTGRGSSGV LTAAV  D  
Sbjct: 328  ELENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQE 387

Query: 1396 SGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLHCPGQHSHTP-NGRCS 1572
            +GE  L    +VL ++GV CIDEFDKM + DRT I        +       H   N RCS
Sbjct: 388  TGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCS 447

Query: 1573 ILAAAN 1590
            +LAAAN
Sbjct: 448  VLAAAN 453


>ref|NP_032592.2| DNA replication licensing factor MCM5 [Mus musculus].
          Length = 734

 Score =  171 bits (434), Expect = 1e-42
 Identities = 136/496 (27%), Positives = 232/496 (46%), Gaps = 17/496 (3%)
 Frame = +1

Query: 154  KEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPELVDSICEN 333
            + + K+FL+++    +     FKY ++L R  +  +  + ++++D+   D EL D + + 
Sbjct: 32   QRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEELADHLHKQ 91

Query: 334  TKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSPQNQYPPE 513
               + +L  +A +E+  +                        R R  G           E
Sbjct: 92   PAEHLQLLEEAAKEVADEVT----------------------RPRPAG----------DE 119

Query: 514  LMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGA 693
            L++  ++  +  S + P  IR +++D +  LV + GI+   S V+ +    +  C  C  
Sbjct: 120  LLQDIQVMLK--SDASPSSIRILKSDMMSHLVKIPGIIISASAVRAKATRISIQCRSCHN 177

Query: 694  ETYQPIQSPTFMPLIMCPSQECQTNRSG------GRLYLQTRGSKFIKFQEMKMQEHSDQ 855
                    P      +   ++C  +++G         ++     K + FQ +K+QE  D 
Sbjct: 178  TLTNIAMRPGLEGYAL--PRKCNMDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDA 235

Query: 856  VPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGF-----RQVVQGLLSETYL 1020
            VP G +PR + +  +        PG+ V++ GI+  I + G      R  V   +  +Y+
Sbjct: 236  VPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIY-SIKKFGLNPSKGRDRVGVGIRSSYI 294

Query: 1021 EAHRIVKMSKSEDDESGAGELS---REELRQIAE-EDFYEKLAASIAPEIYGHEDVKKAX 1188
                I ++       S AG +S    EE R++A   + YE ++ SI+P I+G  D+KKA 
Sbjct: 295  RVLGI-QVDTDGSGRSFAGSVSPQEEEEFRRLAALPNIYELISKSISPSIFGGMDMKKAI 353

Query: 1189 XXXXXXXXDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVR 1365
                     +  P G+  RG+IN+ ++GDPG AKSQLL ++++ +P   YT+G+GSS   
Sbjct: 354  ACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAG 413

Query: 1366 LTAAVLRDSVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLH-CPGQ 1542
            LTA+V+RD  S    + G  +VL + GV CIDEFDKM E DR  I  +     +      
Sbjct: 414  LTASVIRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAG 473

Query: 1543 HSHTPNGRCSILAAAN 1590
             + T N RCS+LAAAN
Sbjct: 474  ITTTLNSRCSVLAAAN 489


>ref|NP_032593.1| DNA replication licensing factor MCM6 [Mus musculus].
          Length = 821

 Score =  167 bits (422), Expect = 3e-41
 Identities = 114/385 (29%), Positives = 184/385 (47%), Gaps = 45/385 (11%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 750
            IRE+ +  +G L  + G V R   V P +V  T+ C  C        Q   +    +C +
Sbjct: 123  IRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIKDVEQQFKYTQPNICRN 182

Query: 751  QECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPG 930
              C   +   R  L T  S+F+ FQ++++QE   ++P G+IPRS+ V++  E    AQ G
Sbjct: 183  PVCANRK---RFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAG 239

Query: 931  DHVSVTGIFLPI------------LRTGFR---------QVVQGLLSETYLE-AHRIVKM 1044
            D    TG  + +              T  R         + ++GL +    + ++R+V +
Sbjct: 240  DRCDFTGALIVVPDVSKLSTPGARAETNSRVSGADGYETEGIRGLRALGVRDLSYRLVFL 299

Query: 1045 S-----------------KSEDDESGAGELSREELRQIAE----EDFYEKLAASIAPEIY 1161
            +                 + +  ES   +++ +E  ++ E    ++ Y  L  S+ P I+
Sbjct: 300  ACHVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIH 359

Query: 1162 GHEDVKKAXXXXXXXXXDQSP-RGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYT 1338
            G+++VK+           ++   G  +RG+IN+C++GDP  AKSQ L ++D  +PR+ YT
Sbjct: 360  GNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVDEFSPRAVYT 419

Query: 1339 TGRGSSGVRLTAAVLRDSVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWST 1518
            +G+ SS   LTAAV+RD  S E  +    L+L + GVCCIDEFDKM   D+  I  +   
Sbjct: 420  SGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDMRDQVAIHEAMEQ 479

Query: 1519 NHLH-CPGQHSHTPNGRCSILAAAN 1590
              +         T N R SILAAAN
Sbjct: 480  QTISITKAGVKATLNARTSILAAAN 504


>ref|NP_079952.2| DNA replication licensing factor MCM8 [Mus musculus].
          Length = 805

 Score =  141 bits (355), Expect = 2e-33
 Identities = 116/362 (32%), Positives = 170/362 (46%), Gaps = 22/362 (6%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 750
            ++ +RA   GK +++RG V RVS +KP      + C  CG     P+    +     CP 
Sbjct: 172  LKNIRATCYGKYISIRGTVVRVSNIKPLCTNMAFQCAACGEIQSFPLPDGKYTLPTKCPV 231

Query: 751  QECQTNRSGGRLYLQTRGSKF---IKFQEMKMQE--HSDQVPVGNIPRSITVLVEGENTR 915
              C+     GR +   R S     + +Q +K+QE     Q   G IPR+I   +  +   
Sbjct: 232  PACR-----GRSFAPLRSSPLTVTLDWQLIKIQELMSDAQREAGRIPRTIECELVHDLVD 286

Query: 916  IAQPGDHVSVTGIF-LPILRTGFRQVVQGLLSETYLEAHRIV--KMSKSEDDESGAG--- 1077
               PGD V+VTGI  +     G R      +   Y+EA+ +   K  K++  E G     
Sbjct: 287  SCVPGDTVTVTGIVKVSNSEEGSRNKNDKCMFLLYIEANSVSNSKGPKAQTAEDGCKHGT 346

Query: 1078 --ELSREELRQI----AEEDFYEKLAASIAPEIYGHEDVKK----AXXXXXXXXXDQSPR 1227
              E S ++L  I    AEE+  + +  S+ P I+GHE VK     A         D   R
Sbjct: 347  LMEFSLKDLYAIREIQAEENLLKLVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNR 406

Query: 1228 GMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGEL 1407
             + IRG+ ++ ++GDPG+ KSQ+L     +APR  Y  G  ++   LT  + +DS SG+ 
Sbjct: 407  -IPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTSSGLTVTLSKDSSSGDF 465

Query: 1408 TLGGWRLVLGEQGVCCIDEFDKMGEADRTPI-TRSWSTNHLHCPGQHSHTPNGRCSILAA 1584
             L    LVLG+QG+C IDEFDKMG   +  +      +  L   G     P  R SI+AA
Sbjct: 466  ALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLP-ARTSIIAA 524

Query: 1585 AN 1590
            AN
Sbjct: 525  AN 526


>ref|NP_082106.2| DNA replication licensing factor MCM9 [Mus musculus].
          Length = 1290

 Score =  138 bits (348), Expect = 1e-32
 Identities = 116/389 (29%), Positives = 185/389 (47%), Gaps = 38/389 (9%)
 Frame = +1

Query: 562  PRVIRE--VRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQC--------GAETYQPI 711
            P ++RE   +   VG  ++V G V R S VK       Y C++C          E Y   
Sbjct: 263  PELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFMVEADFEQYYTF 322

Query: 712  QSPTFMPLIMCPS-QECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVPVGNIPRSIT 888
              P+      CPS   C +++      L +  ++   +QE+K+QE   ++ VG+IPRS+ 
Sbjct: 323  SRPS-----SCPSLASCDSSKFSCLSDLSSSPARCRDYQEIKIQEQVQRLSVGSIPRSMK 377

Query: 889  VLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQV---VQGLLSETYLEAHRIVKMSKSED 1059
            V++E +     + GD +++ G+ +   +   R V   V+ +L   Y++ +          
Sbjct: 378  VILEDDLVDSCKSGDDLTIYGVVMQRWKPFQRDVRCEVEIVLKANYVQVN---------- 427

Query: 1060 DESGAGELSREELRQIAEEDFYE-----------KLAASIAPEIYGHEDVKKAXXXXXXX 1206
            +E  +G +  E+ R+   EDF+E           ++ AS+ P+++G   VK A       
Sbjct: 428  NEQSSGMVMDEDTRK-EFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAG 486

Query: 1207 XXDQSPR-GMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVL 1383
               ++   G ++RG  ++ L+GDPG  KSQ L Y  ++ PRS  TTG GS+   LT   +
Sbjct: 487  GIQRTDAAGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAV 546

Query: 1384 RDSVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPI-------TRSWSTNHLHCPGQ 1542
            +D  SGE  L    LVL + G+CCIDEF+ + E DRT I       T S +   L C   
Sbjct: 547  KD--SGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVC--- 601

Query: 1543 HSHTPNGRCSILAAANL-----PKEATTL 1614
                 N R +ILAA N      PKE+ ++
Sbjct: 602  ---KLNTRTTILAATNPKGQYDPKESVSV 627


  Database: RefSeq49_MP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 15,617,559
  Number of sequences in database:  30,036
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 30036
Number of Hits to DB: 57,275,871
Number of extensions: 1651683
Number of successful extensions: 6329
Number of sequences better than 1.0e-05: 8
Number of HSP's gapped: 6302
Number of HSP's successfully gapped: 9
Length of query: 543
Length of database: 15,617,559
Length adjustment: 106
Effective length of query: 437
Effective length of database: 12,433,743
Effective search space: 5433545691
Effective search space used: 5433545691
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007878
         (1630 letters)

Database: RefSeq49_HP.fasta 
           32,964 sequences; 18,297,164 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_005907.3| DNA replication licensing factor MCM7 isoform 1...   854   0.0  
Alignment   gi|NP_877577.1| DNA replication licensing factor MCM7 isoform 2...   528   e-150
Alignment   gi|NP_002379.2| DNA replication licensing factor MCM3 [Homo sap...   182   6e-46
Alignment   gi|NP_004517.2| DNA replication licensing factor MCM2 [Homo sap...   181   1e-45
Alignment   gi|NP_877423.1| DNA replication licensing factor MCM4 [Homo sap...   179   7e-45
Alignment   gi|NP_005905.2| DNA replication licensing factor MCM4 [Homo sap...   179   7e-45
Alignment   gi|NP_006730.2| DNA replication licensing factor MCM5 [Homo sap...   174   2e-43
Alignment   gi|NP_005906.2| DNA replication licensing factor MCM6 [Homo sap...   166   4e-41
Alignment   gi|NP_115874.3| DNA replication licensing factor MCM8 isoform 1...   147   2e-35
Alignment   gi|NP_877954.1| DNA replication licensing factor MCM8 isoform 2...   141   2e-33

>ref|NP_005907.3| DNA replication licensing factor MCM7 isoform 1 [Homo sapiens].
          Length = 719

 Score =  854 bits (2206), Expect = 0.0
 Identities = 436/487 (89%), Positives = 447/487 (91%), Gaps = 1/487 (0%)
 Frame = +1

Query: 133  LKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPEL 312
            LKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVA+Y+DLDDV EDDPEL
Sbjct: 3    LKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDPEL 62

Query: 313  VDSICENTKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSP 492
            VDSICEN +RYA+LFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPG  RSP
Sbjct: 63   VDSICENARRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGMVRSP 122

Query: 493  QNQYPPELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATY 672
            QNQYP ELMRRFELYFQGPSS+KPRVIREVRADSVGKLVTVRGIVTRVSEVKP+MVVATY
Sbjct: 123  QNQYPAELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATY 182

Query: 673  TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSD 852
            TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGS+FIKFQEMKMQEHSD
Sbjct: 183  TCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSD 242

Query: 853  QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR 1032
            QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR
Sbjct: 243  QVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHR 302

Query: 1033 IVKMSKSEDDESGAGELSREELRQIAEEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXX 1212
            IVKM+KSEDDESGAGEL+REELRQIAEEDFYEKLAASIAPEIYGHEDVKKA         
Sbjct: 303  IVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGV 362

Query: 1213 DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDS 1392
            DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV LTAAVLRDS
Sbjct: 363  DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDS 422

Query: 1393 VSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLH-CPGQHSHTPNGRC 1569
            VSGELTL G  LVL +QGVCCIDEFDKM EADRT I        +         T N RC
Sbjct: 423  VSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARC 482

Query: 1570 SILAAAN 1590
            SILAAAN
Sbjct: 483  SILAAAN 489


>ref|NP_877577.1| DNA replication licensing factor MCM7 isoform 2 [Homo sapiens].
          Length = 543

 Score =  528 bits (1359), Expect = e-150
 Identities = 273/313 (87%), Positives = 278/313 (88%), Gaps = 1/313 (0%)
 Frame = +1

Query: 655  MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMK 834
            MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGS+FIKFQEMK
Sbjct: 1    MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMK 60

Query: 835  MQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSET 1014
            MQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSET
Sbjct: 61   MQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSET 120

Query: 1015 YLEAHRIVKMSKSEDDESGAGELSREELRQIAEEDFYEKLAASIAPEIYGHEDVKKAXXX 1194
            YLEAHRIVKM+KSEDDESGAGEL+REELRQIAEEDFYEKLAASIAPEIYGHEDVKKA   
Sbjct: 121  YLEAHRIVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLL 180

Query: 1195 XXXXXXDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTA 1374
                  DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV LTA
Sbjct: 181  LLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTA 240

Query: 1375 AVLRDSVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLH-CPGQHSH 1551
            AVLRDSVSGELTL G  LVL +QGVCCIDEFDKM EADRT I        +         
Sbjct: 241  AVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILT 300

Query: 1552 TPNGRCSILAAAN 1590
            T N RCSILAAAN
Sbjct: 301  TLNARCSILAAAN 313


>ref|NP_002379.2| DNA replication licensing factor MCM3 [Homo sapiens].
          Length = 808

 Score =  182 bits (463), Expect = 6e-46
 Identities = 128/362 (35%), Positives = 188/362 (51%), Gaps = 7/362 (1%)
 Frame = +1

Query: 526  FELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQ 705
            F +  +G   SK    R + +  +  +V V GIVT+ S V+P++V + + C        +
Sbjct: 98   FYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIER 157

Query: 706  PIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRG--SKFIKFQEMKMQEHSDQVPVGNIPR 879
                 T   L+  PS      +      L+T    S +   Q + +QE  ++ P G +PR
Sbjct: 158  RYSDLT--TLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPR 215

Query: 880  SITVLVEGENTRIAQPGDHVSVTGIF--LPILRTGFRQVVQGLLSETYLEAHRIVKMSKS 1053
            S+ V+++ +    A+PGD V V G +  LP  + G+          T L A  + +MSK 
Sbjct: 216  SVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGT----FRTVLIACNVKQMSKD 271

Query: 1054 EDDESGAGELSR-EELRQIAEEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXXDQS-PR 1227
                  A ++++ ++  +   +D +++LA S+AP I+GH+ VKKA         ++    
Sbjct: 272  AQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLEN 331

Query: 1228 GMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGEL 1407
            G  IRG+INI L+GDP VAKSQLL Y+   APR+  TTGRGSSGV LTAAV  D  +GE 
Sbjct: 332  GSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGER 391

Query: 1408 TLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLHCPGQHSHTP-NGRCSILAA 1584
             L    +VL ++GV CIDEFDKM + DRT I        +       H   N RCS+LAA
Sbjct: 392  RLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAA 451

Query: 1585 AN 1590
            AN
Sbjct: 452  AN 453


>ref|NP_004517.2| DNA replication licensing factor MCM2 [Homo sapiens].
          Length = 904

 Score =  181 bits (460), Expect = 1e-45
 Identities = 117/348 (33%), Positives = 184/348 (52%), Gaps = 8/348 (2%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCG--AETYQPIQSPTFMPLIMC 744
            +R +R   + +L+   G+VT  + V P++ +  Y C++C      +   Q+    P   C
Sbjct: 294  LRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPG-SC 352

Query: 745  PSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQ 924
            P  ECQ   S G   +    + +  +Q +++QE   +V  G +PRS   ++  +     +
Sbjct: 353  P--ECQ---SAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCK 407

Query: 925  PGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMSKSEDDESGAGELSREELRQ 1104
            PGD + +TGI+               +  T + A+ + K    +D++   GEL+ E+++ 
Sbjct: 408  PGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAK----KDNKVAVGELTDEDVKM 463

Query: 1105 IA----EEDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXXDQSPRGM-KIRGNINICLMG 1269
            I     ++   EK+ ASIAP IYGHED+K+           ++P G  K+RG+IN+ L G
Sbjct: 464  ITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCG 523

Query: 1270 DPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGELTLGGWRLVLGEQGV 1449
            DPG AKSQ L YI++++ R+ +TTG+G+S V LTA V R  VS E TL    LVL ++GV
Sbjct: 524  DPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGV 583

Query: 1450 CCIDEFDKMGEADRTPITRSWSTNHLHCPGQHSHTP-NGRCSILAAAN 1590
            C IDEFDKM + DRT I  +     +        T    RC+++AAAN
Sbjct: 584  CLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAAN 631


>ref|NP_877423.1| DNA replication licensing factor MCM4 [Homo sapiens].
          Length = 863

 Score =  179 bits (454), Expect = 7e-45
 Identities = 145/502 (28%), Positives = 233/502 (46%), Gaps = 23/502 (4%)
 Frame = +1

Query: 154  KEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPELVDSICEN 333
            KE  ++FLQ F   D L K++   G  +    + ++      L ++       ++  CE+
Sbjct: 163  KENFQRFLQRFI--DPLAKEEENVGIDITEPLYMQR------LGEINVIGEPFLNVNCEH 214

Query: 334  TKRYAR-LFADAV---QELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSPQNQ 501
             K + + L+   +   QE++P +     VN+   D Y                       
Sbjct: 215  IKSFDKNLYRQLISYPQEVIPTFDM--AVNEIFFDRY----------------------- 249

Query: 502  YPPELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCD 681
              P+ +   ++  +  ++ K + +R +  + + +L+T+ G+V R S++ P M  A + C 
Sbjct: 250  --PDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQ 307

Query: 682  QCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVP 861
             C   T   +         +C    C T  S   ++ +   S F   Q +K+QE  + +P
Sbjct: 308  VCAHTTRVEMDRGRIAEPSVCG--RCHTTHSMALIHNR---SLFSDKQMIKLQESPEDMP 362

Query: 862  VGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPI-LRTGFRQVVQGLLSETYLEAHRIV 1038
             G  P ++ +    +     QPGD V+VTGI+  + +R   R      + +T+++     
Sbjct: 363  AGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYR 422

Query: 1039 KMSKSED---DESGAGELSREELRQIAEE-----DFYEKLAASIAPEIYGHEDVKKAXXX 1194
            K         DE    +L  E+  ++ +E     D YE+LA+++AP IY HED+KK    
Sbjct: 423  KTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILL 482

Query: 1195 XXXXXX--DQSPRGM-KIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVR 1365
                    D S  G  K R  INI L GDPG +KSQLL Y+  L PR QYT+G+GSS V 
Sbjct: 483  QLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVG 542

Query: 1366 LTAAVLRDSVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPI-------TRSWSTNH 1524
            LTA V++D  + +L L    LVL + G+CCIDEFDKM E+ R+ +       T S +   
Sbjct: 543  LTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAG 602

Query: 1525 LHCPGQHSHTPNGRCSILAAAN 1590
            + C        N R S+LAAAN
Sbjct: 603  IIC------QLNARTSVLAAAN 618


>ref|NP_005905.2| DNA replication licensing factor MCM4 [Homo sapiens].
          Length = 863

 Score =  179 bits (454), Expect = 7e-45
 Identities = 145/502 (28%), Positives = 233/502 (46%), Gaps = 23/502 (4%)
 Frame = +1

Query: 154  KEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPELVDSICEN 333
            KE  ++FLQ F   D L K++   G  +    + ++      L ++       ++  CE+
Sbjct: 163  KENFQRFLQRFI--DPLAKEEENVGIDITEPLYMQR------LGEINVIGEPFLNVNCEH 214

Query: 334  TKRYAR-LFADAV---QELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSPQNQ 501
             K + + L+   +   QE++P +     VN+   D Y                       
Sbjct: 215  IKSFDKNLYRQLISYPQEVIPTFDM--AVNEIFFDRY----------------------- 249

Query: 502  YPPELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCD 681
              P+ +   ++  +  ++ K + +R +  + + +L+T+ G+V R S++ P M  A + C 
Sbjct: 250  --PDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQ 307

Query: 682  QCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVP 861
             C   T   +         +C    C T  S   ++ +   S F   Q +K+QE  + +P
Sbjct: 308  VCAHTTRVEMDRGRIAEPSVCG--RCHTTHSMALIHNR---SLFSDKQMIKLQESPEDMP 362

Query: 862  VGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPI-LRTGFRQVVQGLLSETYLEAHRIV 1038
             G  P ++ +    +     QPGD V+VTGI+  + +R   R      + +T+++     
Sbjct: 363  AGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYR 422

Query: 1039 KMSKSED---DESGAGELSREELRQIAEE-----DFYEKLAASIAPEIYGHEDVKKAXXX 1194
            K         DE    +L  E+  ++ +E     D YE+LA+++AP IY HED+KK    
Sbjct: 423  KTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILL 482

Query: 1195 XXXXXX--DQSPRGM-KIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVR 1365
                    D S  G  K R  INI L GDPG +KSQLL Y+  L PR QYT+G+GSS V 
Sbjct: 483  QLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVG 542

Query: 1366 LTAAVLRDSVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPI-------TRSWSTNH 1524
            LTA V++D  + +L L    LVL + G+CCIDEFDKM E+ R+ +       T S +   
Sbjct: 543  LTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAG 602

Query: 1525 LHCPGQHSHTPNGRCSILAAAN 1590
            + C        N R S+LAAAN
Sbjct: 603  IIC------QLNARTSVLAAAN 618


>ref|NP_006730.2| DNA replication licensing factor MCM5 [Homo sapiens].
          Length = 734

 Score =  174 bits (442), Expect = 2e-43
 Identities = 135/496 (27%), Positives = 233/496 (46%), Gaps = 17/496 (3%)
 Frame = +1

Query: 154  KEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAMYIDLDDVTEDDPELVDSICEN 333
            + + K+FL+++    +     FKY ++L R  +  +  + ++++D+   D +L D + + 
Sbjct: 32   QRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQ 91

Query: 334  TKRYARLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGAARSPQNQYPPE 513
               + +L  +A +E+  +        ++VL    + ++M++                   
Sbjct: 92   PAEHLQLLEEAAKEVADEVTRPRPSGEEVLQ---DIQVMLK------------------- 129

Query: 514  LMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGA 693
                        S + P  IR +++D +  LV + GI+   S V+ +    +  C  C  
Sbjct: 130  ------------SDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRN 177

Query: 694  ETYQPIQSPTFMPLIMCPSQECQTNRSG------GRLYLQTRGSKFIKFQEMKMQEHSDQ 855
                    P      +   ++C T+++G         ++     K + FQ +K+QE  D 
Sbjct: 178  TLTNIAMRPGLEGYAL--PRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDA 235

Query: 856  VPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGF-----RQVVQGLLSETYL 1020
            VP G +PR + +  +        PG+ V++ GI+  I + G      R  V   +  +Y+
Sbjct: 236  VPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIY-SIKKFGLTTSRGRDRVGVGIRSSYI 294

Query: 1021 EAHRIVKMSKSEDDESGAGELS---REELRQIAE-EDFYEKLAASIAPEIYGHEDVKKAX 1188
                I ++       S AG +S    EE R++A   + YE ++ SIAP I+G  D+KKA 
Sbjct: 295  RVLGI-QVDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAI 353

Query: 1189 XXXXXXXXDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVR 1365
                     +  P G+  RG+IN+ ++GDPG AKSQLL ++++ +P   YT+G+GSS   
Sbjct: 354  ACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAG 413

Query: 1366 LTAAVLRDSVSGELTLGGWRLVLGEQGVCCIDEFDKMGEADRTPITRSWSTNHLH-CPGQ 1542
            LTA+V+RD  S    + G  +VL + GV CIDEFDKM E DR  I  +     +      
Sbjct: 414  LTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAG 473

Query: 1543 HSHTPNGRCSILAAAN 1590
             + T N RCS+LAAAN
Sbjct: 474  ITTTLNSRCSVLAAAN 489


>ref|NP_005906.2| DNA replication licensing factor MCM6 [Homo sapiens].
          Length = 821

 Score =  166 bits (421), Expect = 4e-41
 Identities = 120/405 (29%), Positives = 193/405 (47%), Gaps = 46/405 (11%)
 Frame = +1

Query: 514  LMRRFELYFQG-PSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCG 690
            L + F + FQ  P+  K   IRE+ +  +G L  + G V R   V P +V  T+ C  C 
Sbjct: 106  LAKDFYVAFQDLPTRHK---IRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQ 162

Query: 691  AETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKMQEHSDQVPVGN 870
                   Q   +    +C +  C   R   R  L T  S+F+ FQ++++QE   ++P G+
Sbjct: 163  TVIRDVEQQFKYTQPNICRNPVCANRR---RFLLDTNKSRFVDFQKVRIQETQAELPRGS 219

Query: 871  IPRSITVLVEGENTRIAQPGDHVSVTGIFLPI------------LRTGFR---------Q 987
            IPRS+ V++  E    AQ GD    TG  + +              T  R         +
Sbjct: 220  IPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYETE 279

Query: 988  VVQGLLSETYLE-AHRIVKMS-----------------KSEDDESGAGELSREELRQIAE 1113
             ++GL +    + ++R+V ++                 + +  ES   +++ +E  ++ E
Sbjct: 280  GIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFE 339

Query: 1114 ----EDFYEKLAASIAPEIYGHEDVKKAXXXXXXXXXDQSP-RGMKIRGNINICLMGDPG 1278
                ++ Y  L  S+ P I+G+++VK+           ++   G  +RG+IN+C++GDP 
Sbjct: 340  MSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPS 399

Query: 1279 VAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGELTLGGWRLVLGEQGVCCI 1458
             AKSQ L +++  +PR+ YT+G+ SS   LTAAV+RD  S E  +    L+L + GVCCI
Sbjct: 400  TAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCI 459

Query: 1459 DEFDKMGEADRTPITRSWSTNHLH-CPGQHSHTPNGRCSILAAAN 1590
            DEFDKM   D+  I  +     +         T N R SILAAAN
Sbjct: 460  DEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAAN 504


>ref|NP_115874.3| DNA replication licensing factor MCM8 isoform 1 [Homo sapiens].
          Length = 840

 Score =  147 bits (372), Expect = 2e-35
 Identities = 117/362 (32%), Positives = 171/362 (47%), Gaps = 22/362 (6%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 750
            ++ VRA+  GK + +RG V RVS +KP      + C  CG     P+    +     CP 
Sbjct: 207  LKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCPV 266

Query: 751  QECQTNRSGGRLYLQTRGSKF---IKFQEMKMQE--HSDQVPVGNIPRSITVLVEGENTR 915
              C+     GR +   R S     + +Q +K+QE    DQ   G IPR+I   +  +   
Sbjct: 267  PVCR-----GRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVD 321

Query: 916  IAQPGDHVSVTGIF-LPILRTGFRQVVQGLLSETYLEAHRIV----KMSKSEDDESGAGE 1080
               PGD V++TGI  +     G R      +   Y+EA+ I     + +KS +D    G 
Sbjct: 322  SCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGM 381

Query: 1081 LSREELRQI-------AEEDFYEKLAASIAPEIYGHEDVKK----AXXXXXXXXXDQSPR 1227
            L    L+ +       AEE+ ++ +  S+ P I+GHE VK     A         D   R
Sbjct: 382  LMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNR 441

Query: 1228 GMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGEL 1407
             + IRG+ +I ++GDPG+ KSQ+L     +APR  Y  G  ++   LT  + +DS SG+ 
Sbjct: 442  -IPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDF 500

Query: 1408 TLGGWRLVLGEQGVCCIDEFDKMGEADRTPI-TRSWSTNHLHCPGQHSHTPNGRCSILAA 1584
             L    LVLG+QG+C IDEFDKMG   +  +      +  L   G     P  R SI+AA
Sbjct: 501  ALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLP-ARTSIIAA 559

Query: 1585 AN 1590
            AN
Sbjct: 560  AN 561


>ref|NP_877954.1| DNA replication licensing factor MCM8 isoform 2 [Homo sapiens].
          Length = 824

 Score =  141 bits (355), Expect = 2e-33
 Identities = 113/357 (31%), Positives = 165/357 (46%), Gaps = 17/357 (4%)
 Frame = +1

Query: 571  IREVRADSVGKLVTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 750
            ++ VRA+  GK + +RG V RVS +KP      + C  CG     P+    +     CP 
Sbjct: 207  LKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCPV 266

Query: 751  QECQTNRSGGRLYLQTRGSKF---IKFQEMKMQE--HSDQVPVGNIPRSITVLVEGENTR 915
              C+     GR +   R S     + +Q +K+QE    DQ   G IPR+I   +  +   
Sbjct: 267  PVCR-----GRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVD 321

Query: 916  IAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMSKSEDDESGAGELSREE 1095
               PGD V++TGI           V      E    ++   + +KS +D    G L    
Sbjct: 322  SCVPGDTVTITGI-----------VKVSNAEEANSISNSKGQKTKSSEDGCKHGMLMEFS 370

Query: 1096 LRQI-------AEEDFYEKLAASIAPEIYGHEDVKK----AXXXXXXXXXDQSPRGMKIR 1242
            L+ +       AEE+ ++ +  S+ P I+GHE VK     A         D   R + IR
Sbjct: 371  LKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNR-IPIR 429

Query: 1243 GNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVRLTAAVLRDSVSGELTLGGW 1422
            G+ +I ++GDPG+ KSQ+L     +APR  Y  G  ++   LT  + +DS SG+  L   
Sbjct: 430  GDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAG 489

Query: 1423 RLVLGEQGVCCIDEFDKMGEADRTPI-TRSWSTNHLHCPGQHSHTPNGRCSILAAAN 1590
             LVLG+QG+C IDEFDKMG   +  +      +  L   G     P  R SI+AAAN
Sbjct: 490  ALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLP-ARTSIIAAAN 545


  Database: RefSeq49_HP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,297,164
  Number of sequences in database:  32,964
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 32964
Number of Hits to DB: 67,815,421
Number of extensions: 1981417
Number of successful extensions: 7220
Number of sequences better than 1.0e-05: 12
Number of HSP's gapped: 7181
Number of HSP's successfully gapped: 13
Length of query: 543
Length of database: 18,297,164
Length adjustment: 107
Effective length of query: 436
Effective length of database: 14,770,016
Effective search space: 6439726976
Effective search space used: 6439726976
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)

BLASTN 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-007878
         (1630 letters)

Database: Sscrofa_10.2.fasta 
           4582 sequences; 2,808,509,378 total letters

Searching..................................................done

 ***** No hits found ******


  Database: Sscrofa_10.2.fasta
    Posted date:  Nov 16, 2011 10:34 AM
  Number of letters in database: 2,808,509,378
  Number of sequences in database:  4582
  
Lambda     K      H
    1.37    0.711     1.31 

Gapped
Lambda     K      H
    1.37    0.711     1.31 


Matrix: blastn matrix:1 -3
Gap Penalties: Existence: 5, Extension: 2
Number of Sequences: 4582
Number of Hits to DB: 41,284,629
Number of extensions: 250
Number of successful extensions: 250
Number of sequences better than 1.0e-05: 0
Number of HSP's gapped: 250
Number of HSP's successfully gapped: 0
Length of query: 1630
Length of database: 2,808,509,378
Length adjustment: 22
Effective length of query: 1608
Effective length of database: 2,808,408,574
Effective search space: 4515920986992
Effective search space used: 4515920986992
X1: 11 (21.8 bits)
X2: 15 (29.7 bits)
X3: 50 (99.1 bits)
S1: 18 (36.2 bits)
S2: 30 (60.0 bits)