Animal-Genome cDNA 20110601C-008115

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-008115
         (1128 letters)

Database: RefSeq49_BP.fasta 
           33,088 sequences; 17,681,374 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_776457.1| cathepsin L2 precursor [Bos taurus].                 613   e-180
Alignment   gi|NP_001077155.1| cathepsin L1 [Bos taurus].                        521   e-152
Alignment   gi|NP_001029607.1| cathepsin K [Bos taurus].                         315   1e-86
Alignment   gi|NP_001028787.1| cathepsin S precursor [Bos taurus].               297   1e-80
Alignment   gi|NP_001029557.1| pro-cathepsin H precursor [Bos taurus].           197   1e-50
Alignment   gi|NP_001068884.1| cathepsin F [Bos taurus].                         187   1e-47
Alignment   gi|XP_002694471.1| PREDICTED: cathepsin O preproprotein-like [B...   124   2e-28
Alignment   gi|XP_874012.3| PREDICTED: cathepsin O [Bos taurus].                 124   2e-28
Alignment   gi|NP_001028789.1| dipeptidyl peptidase 1 [Bos taurus].              114   1e-25
Alignment   gi|NP_776456.1| cathepsin B precursor [Bos taurus].                   93   5e-19

>ref|NP_776457.1| cathepsin L2 precursor [Bos taurus].
          Length = 334

 Score =  613 bits (1582), Expect(2) = e-180
 Identities = 283/318 (88%), Positives = 300/318 (94%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M PS FLT LCLG+ASAAPKLD NLDA W++WKATH RLYGMNEE WRRAVWEKN K+I+
Sbjct: 1    MNPSFFLTVLCLGVASAAPKLDPNLDAHWHQWKATHRRLYGMNEEEWRRAVWEKNKKIID 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
            LHNQEYS+GKH F MAMNAFGDMTNEEFRQVMNGFQNQKHKKGK+FHE L+++VPKSVDW
Sbjct: 61   LHNQEYSEGKHAFRMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKLFHEPLLVDVPKSVDW 120

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
             +KGYVT VKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSR QGNQGCNG
Sbjct: 121  TKKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNQGCNG 180

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV 816
            GLMDNAFQY+KDNGGLD+EESYPYL  +TNSC YKPECSAANDTGFVDIPQREKALMKAV
Sbjct: 181  GLMDNAFQYIKDNGGLDSEESYPYLATDTNSCNYKPECSAANDTGFVDIPQREKALMKAV 240

Query: 817  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 996
            ATVGPISVAIDAGH+SFQFYKSGIYYDPDCS KDLDHGVLVVGYGFEGTDSN++KFWIVK
Sbjct: 241  ATVGPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSNNNKFWIVK 300

Query: 997  NSWGPEWGWNGYVKMAKD 1050
            NSWGPEWGWNGYVKMAKD
Sbjct: 301  NSWGPEWGWNGYVKMAKD 318



 Score = 36.2 bits (82), Expect(2) = e-180
 Identities = 14/18 (77%), Positives = 17/18 (94%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            + +NNHCGI+TAASYPTV
Sbjct: 317  KDQNNHCGIATAASYPTV 334


>ref|NP_001077155.1| cathepsin L1 [Bos taurus].
          Length = 333

 Score =  521 bits (1341), Expect(2) = e-152
 Identities = 240/318 (75%), Positives = 274/318 (86%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M PSL LTALCLGIASAAPK D +LD  W  WKA H + Y +NEEGWR+AVW+KNMKMIE
Sbjct: 1    MNPSLLLTALCLGIASAAPKFDHSLDTQWKLWKAAHRKPYDLNEEGWRKAVWKKNMKMIE 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
            LHNQEYSQGKH FSMAMNAFGDMTNEEFR  MNGFQ QK+KKGK FHE++   +P SVDW
Sbjct: 61   LHNQEYSQGKHSFSMAMNAFGDMTNEEFRHTMNGFQRQKNKKGKEFHETIFASIPPSVDW 120

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
            REKGYVT VKNQG+CGSCWAFSATGALEGQMF+KTGKLVSLSEQNLVDCS+P+GN+GC+G
Sbjct: 121  REKGYVTPVKNQGKCGSCWAFSATGALEGQMFQKTGKLVSLSEQNLVDCSQPEGNRGCHG 180

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV 816
            G +DNAFQYV D GGLD+EESYPY G    +C Y P  SAAN+TGFVD+P++EKALMKAV
Sbjct: 181  GFIDNAFQYVLDVGGLDSEESYPYTGL-VGTCLYNPNNSAANETGFVDLPKQEKALMKAV 239

Query: 817  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 996
            A +GPISVA+DA + SFQFYKSGIYY+P+CSS+ +DH VLVVGYGFEG DS+ +K+W+VK
Sbjct: 240  ANLGPISVAVDAHNPSFQFYKSGIYYEPNCSSESVDHAVLVVGYGFEGADSDDNKYWLVK 299

Query: 997  NSWGPEWGWNGYVKMAKD 1050
            NSWG  WG NGY+KMAKD
Sbjct: 300  NSWGEHWGMNGYIKMAKD 317



 Score = 35.8 bits (81), Expect(2) = e-152
 Identities = 14/18 (77%), Positives = 16/18 (88%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            + RNNHCGI+T ASYPTV
Sbjct: 316  KDRNNHCGIATMASYPTV 333


>ref|NP_001029607.1| cathepsin K [Bos taurus].
          Length = 334

 Score =  315 bits (807), Expect(2) = 1e-86
 Identities = 162/317 (51%), Positives = 211/317 (66%), Gaps = 5/317 (1%)
 Frame = +1

Query: 115  LTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMN-EEGWRRAVWEKNMKMIELHNQE 291
            LT L L + S A   ++ LD  W  WK T+ + Y    +E  RR +WEKN+K I +HN E
Sbjct: 9    LTVLLLPVVSFALYPEEILDTQWELWKKTYRKQYNSKGDEISRRLIWEKNLKHISIHNLE 68

Query: 292  YSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQ---NQKHKKGKVFHESLVLEVPKSVDWRE 462
             S G H + +AMN  GDMT+EE  Q M G +   ++      ++        P SVD+R+
Sbjct: 69   ASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPASRSRSNDTLYIPDWEGRAPDSVDYRK 128

Query: 463  KGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGL 642
            KGYVT VKNQGQCGSCWAFS+ GALEGQ+ +KTGKL++LS QNLVDC     N GC GG 
Sbjct: 129  KGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC--VSENDGCGGGY 186

Query: 643  MDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQ-REKALMKAVA 819
            M NAFQYV+ N G+D+E++YPY+G++ N C Y P   AA   G+ +IP+  EKAL +AVA
Sbjct: 187  MTNAFQYVQKNRGIDSEDAYPYVGQDEN-CMYNPTGKAAKCRGYREIPEGNEKALKRAVA 245

Query: 820  TVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKN 999
             VGPISVAIDA  +SFQFY+ G+YYD +C+S +L+H VL VGYG +      +K WI+KN
Sbjct: 246  RVGPISVAIDASLTSFQFYRKGVYYDENCNSDNLNHAVLAVGYGIQ----KGNKHWIIKN 301

Query: 1000 SWGPEWGWNGYVKMAKD 1050
            SWG  WG  GY+ MA++
Sbjct: 302  SWGENWGNKGYILMARN 318



 Score = 24.6 bits (52), Expect(2) = 1e-86
 Identities = 9/16 (56%), Positives = 12/16 (75%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYP 1094
            R +NN CGI+  AS+P
Sbjct: 317  RNKNNACGIANLASFP 332


>ref|NP_001028787.1| cathepsin S precursor [Bos taurus].
          Length = 331

 Score =  297 bits (760), Expect = 1e-80
 Identities = 158/318 (49%), Positives = 207/318 (65%), Gaps = 7/318 (2%)
 Frame = +1

Query: 160  DQNLDADWYKWKATHGRLYG-MNEEGWRRAVWEKNMKMIELHNQEYSQGKHGFSMAMNAF 336
            D  LD  W  WK T+G+ Y   NEE  RR +WEKN+K + LHN E+S G H + + MN  
Sbjct: 21   DPTLDHHWDLWKKTYGKQYKEKNEEVARRLIWEKNLKTVTLHNLEHSMGMHSYELGMNHL 80

Query: 337  GDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLE-VPKSVDWREKGYVTAVKNQGQCGSCW 513
            GDMT+EE   +M+  +        V ++S   + +P S+DWREKG VT VK QG CGSCW
Sbjct: 81   GDMTSEEVISLMSSLRVPSQWPRNVTYKSDPNQKLPDSMDWREKGCVTEVKYQGACGSCW 140

Query: 514  AFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ-GNQGCNGGLMDNAFQYVKDNGGLDT 690
            AFSA GALE Q+  KTGKLVSLS QNLVDCS  + GN+GCNGG M  AFQY+ DN G+D+
Sbjct: 141  AFSAVGALEAQVKLKTGKLVSLSAQNLVDCSTAKYGNKGCNGGFMTEAFQYIIDNNGIDS 200

Query: 691  EESYPYLGRETNSCTYKPECSAANDTGFVDIP-QREKALMKAVATVGPISVAIDAGHSSF 867
            E SYPY   +   C Y  +  AA  + ++++P   E+AL +AVA  GP+SV IDA HSSF
Sbjct: 201  EASYPYKAMD-GKCQYDVKNRAATCSRYIELPFGSEEALKEAVANKGPVSVGIDASHSSF 259

Query: 868  QFYKSGIYYDPDCSSKDLDHGVLVVGYG-FEGTDSNSSKFWIVKNSWGPEWGWNGYVKMA 1044
              YK+G+YYDP C +++++HGVLVVGYG  +G D     +W+VKNSWG  +G  GY++MA
Sbjct: 260  FLYKTGVYYDPSC-TQNVNHGVLVVGYGNLDGKD-----YWLVKNSWGLHFGDQGYIRMA 313

Query: 1045 KDP--ETTTVEFPQQPAI 1092
            ++         +P  P I
Sbjct: 314  RNSGNHCGIANYPSYPEI 331


>ref|NP_001029557.1| pro-cathepsin H precursor [Bos taurus].
          Length = 335

 Score =  197 bits (502), Expect = 1e-50
 Identities = 111/285 (38%), Positives = 153/285 (53%), Gaps = 4/285 (1%)
 Frame = +1

Query: 190  WKATHGRLYGMNEEGWRRAVWEKNMKMIELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQV 369
            W   H + Y   E   R   +  N++ I  HN       H F M +N F DM+ +E ++ 
Sbjct: 38   WMVQHQKKYSSEEYYHRLQAFASNLREINAHNAR----NHTFKMGLNQFSDMSFDELKRK 93

Query: 370  MNGFQNQKHKKGKVFHESLVLEVPKSVDWREKG-YVTAVKNQGQCGSCWAFSATGALEGQ 546
                + Q     K  +       P S+DWR+KG +VT VKNQG CGSCW FS TGALE  
Sbjct: 94   YLWSEPQNCSATKSNYLRGTGPYPPSMDWRKKGNFVTPVKNQGSCGSCWTFSTTGALESA 153

Query: 547  MFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYLGRETN 726
            +   TGKL  L+EQ LVDC++   N GC GGL   AF+Y++ N G+  E++YPY G++  
Sbjct: 154  VAIATGKLPFLAEQQLVDCAQNFNNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYRGQD-G 212

Query: 727  SCTYKPECSAANDTGFVDIP-QREKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPD 903
             C Y+P  + A      +I    E+A+++AVA   P+S A +   + F  Y+ GIY    
Sbjct: 213  DCKYQPSKAIAFVKDVANITLNDEEAMVEAVALHNPVSFAFEV-TADFMMYRKGIYSSTS 271

Query: 904  C--SSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGWNGY 1032
            C  +   ++H VL VGYG    +     +WIVKNSWGP WG  GY
Sbjct: 272  CHKTPDKVNHAVLAVGYG----EEKGIPYWIVKNSWGPNWGMKGY 312


>ref|NP_001068884.1| cathepsin F [Bos taurus].
          Length = 460

 Score =  187 bits (475), Expect = 1e-47
 Identities = 110/283 (38%), Positives = 159/283 (56%), Gaps = 5/283 (1%)
 Frame = +1

Query: 199  THGRLYGMNEEG-WRRAVWEKNM-KMIELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQV- 369
            T+ R Y   EE  WR +V+  NM +  ++   +    ++G    +  F D+T EEFR + 
Sbjct: 169  TYNRTYDSQEEASWRMSVFANNMVRAQKIQALDRGTARYG----VTKFSDLTEEEFRTIY 224

Query: 370  MNGFQNQKHKKGKVFHESLVLEVPKSVDWREKGYVTAVKNQGQCGSCWAFSATGALEGQM 549
            +N        +     + +    P   DWR KG VT VK+QG CGSCWAFS TG +EGQ 
Sbjct: 225  LNPLLKDAPGRNMRPAQPVTDVPPPQWDWRNKGAVTNVKDQGMCGSCWAFSVTGNVEGQW 284

Query: 550  FRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYLGRETNS 729
            F K G L+SLSEQ L+DC +   ++ C GGL  NA+  ++  GGL+TE+ Y Y GR   +
Sbjct: 285  FLKRGTLLSLSEQELLDCDKT--DKACLGGLPSNAYSAIRTLGGLETEDDYSYRGR-LQT 341

Query: 730  CTYKPECSAANDTGFVDIPQREKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYD--PD 903
            C++  E +       V++ + E+ L   +A  GP+S+AI+A     QFY+ GI +   P 
Sbjct: 342  CSFSAEKAKVYINDSVELSKNEQKLAAWLAKNGPVSIAINA--FGMQFYRHGISHPLRPL 399

Query: 904  CSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGWNGY 1032
            CS   +DH VL+VGYG    + ++  FW +KNSWG +WG  GY
Sbjct: 400  CSPWLIDHAVLLVGYG----NRSAIPFWAIKNSWGTDWGEEGY 438


>ref|XP_002694471.1| PREDICTED: cathepsin O preproprotein-like [Bos taurus].
          Length = 375

 Score =  124 bits (311), Expect = 2e-28
 Identities = 77/207 (37%), Positives = 109/207 (52%), Gaps = 3/207 (1%)
 Frame = +1

Query: 430  LEVPKSVDWREKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSR 609
            L +P   DWR+K  VT V+NQ  CG CWAFS  GA+E     K   L  LS Q ++DCS 
Sbjct: 160  LSLPLRFDWRDKHVVTQVRNQKTCGGCWAFSVVGAVESVCAIKGQPLEVLSVQQVIDCS- 218

Query: 610  PQGNQGCNGGLMDNAFQYV-KDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGF--VD 780
               N GCNGG   +A  ++ K    L  +  YP+  +      +    S ++  G+   D
Sbjct: 219  -YSNYGCNGGSPLSALYWLNKLQVKLVRDSEYPFQAQNGLCRYFSDSHSGSSIKGYSAYD 277

Query: 781  IPQREKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEG 960
               +E  + +A+  +GP+ V +DA   S+Q Y  GI     CSS + +H VLV G+   G
Sbjct: 278  FSGQEDKMAEALLALGPLIVVVDA--MSWQDYLGGI-IQHHCSSGEANHAVLVTGFDKTG 334

Query: 961  TDSNSSKFWIVKNSWGPEWGWNGYVKM 1041
                S  +WIV+NSWG  WG +GYV++
Sbjct: 335  ----SIPYWIVRNSWGTSWGIDGYVRV 357


>ref|XP_874012.3| PREDICTED: cathepsin O [Bos taurus].
          Length = 384

 Score =  124 bits (311), Expect = 2e-28
 Identities = 77/207 (37%), Positives = 109/207 (52%), Gaps = 3/207 (1%)
 Frame = +1

Query: 430  LEVPKSVDWREKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSR 609
            L +P   DWR+K  VT V+NQ  CG CWAFS  GA+E     K   L  LS Q ++DCS 
Sbjct: 169  LSLPLRFDWRDKHVVTQVRNQKTCGGCWAFSVVGAVESVCAIKGQPLEVLSVQQVIDCS- 227

Query: 610  PQGNQGCNGGLMDNAFQYV-KDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGF--VD 780
               N GCNGG   +A  ++ K    L  +  YP+  +      +    S ++  G+   D
Sbjct: 228  -YSNYGCNGGSPLSALYWLNKLQVKLVRDSEYPFQAQNGLCRYFSDSHSGSSIKGYSAYD 286

Query: 781  IPQREKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEG 960
               +E  + +A+  +GP+ V +DA   S+Q Y  GI     CSS + +H VLV G+   G
Sbjct: 287  FSGQEDKMAEALLALGPLIVVVDA--MSWQDYLGGI-IQHHCSSGEANHAVLVTGFDKTG 343

Query: 961  TDSNSSKFWIVKNSWGPEWGWNGYVKM 1041
                S  +WIV+NSWG  WG +GYV++
Sbjct: 344  ----SIPYWIVRNSWGTSWGIDGYVRV 366


>ref|NP_001028789.1| dipeptidyl peptidase 1 [Bos taurus].
          Length = 463

 Score =  114 bits (286), Expect = 1e-25
 Identities = 81/239 (33%), Positives = 121/239 (50%), Gaps = 16/239 (6%)
 Frame = +1

Query: 427  VLEVPKSVDWREK---GYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVS--LSEQN 591
            +L +P S DWR      +VT V+NQG CGSC++F++ G +E ++   T    +  LS Q 
Sbjct: 228  ILHLPTSWDWRNVHGINFVTPVRNQGSCGSCYSFASMGMMEARIRILTNNTQTPILSPQE 287

Query: 592  LVDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTG 771
            +V CS  Q  QGC GG           + GL  E+ +PY G ++  C  K  C     + 
Sbjct: 288  VVSCS--QYAQGCEGGFPYLIAGKYAQDFGLVEEDCFPYTGTDS-PCRLKEGCFRYYSSE 344

Query: 772  FVDIPQR----EKALMKA-VATVGPISVAIDAGHSSFQFYKSGIYY-----DPDCSSKDL 921
            +  +        +ALMK  +   GP++VA +  +  F  Y+ G+Y+     DP    +  
Sbjct: 345  YHYVGGFYGGCNEALMKLELVHQGPMAVAFEV-YDDFLHYRKGVYHHTGLRDPFNPFELT 403

Query: 922  DHGVLVVGYGFEGTDSNSS-KFWIVKNSWGPEWGWNGYVKMAKDPETTTVEFPQQPAIP 1095
            +H VL+VGYG   TD+ S   +WIVKNSWG  WG NGY ++ +  +   +E     A P
Sbjct: 404  NHAVLLVGYG---TDAASGLDYWIVKNSWGTSWGENGYFRIRRGTDECAIESIALAATP 459


>ref|NP_776456.1| cathepsin B precursor [Bos taurus].
          Length = 335

 Score = 92.8 bits (229), Expect = 5e-19
 Identities = 67/249 (26%), Positives = 111/249 (44%), Gaps = 37/249 (14%)
 Frame = +1

Query: 436  VPKSVDWREKG----YVTAVKNQGQCGSCWAFSATGALEGQM-FRKTGKL-VSLSEQNLV 597
            +P+S D RE+      +  +++QG CGSCWAF A  A+  ++     G++ V +S ++++
Sbjct: 80   LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 139

Query: 598  DCSRPQGNQGCNGGLMDNAFQYVKD----NGGLDTEE------SYPYLGRETNS----CT 735
             C   +   GCNGG    A+ +       +GGL          S P      N     CT
Sbjct: 140  TCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCT 199

Query: 736  YK---PECSAANDTGF--------------VDIPQREKALMKAVATVGPISVAIDAGHSS 864
             +   P+CS   + G+                +   EK +M  +   GP+  A    +S 
Sbjct: 200  GEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSV-YSD 258

Query: 865  FQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGWNGYVKMA 1044
            F  YKSG+Y           H + ++G+G E    N + +W+V NSW  +WG NG+ K+ 
Sbjct: 259  FLLYKSGVYQHVSGEIMG-GHAIRILGWGVE----NGTPYWLVGNSWNTDWGDNGFFKIL 313

Query: 1045 KDPETTTVE 1071
            +  +   +E
Sbjct: 314  RGQDHCGIE 322


  Database: RefSeq49_BP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 17,681,374
  Number of sequences in database:  33,088
  
Lambda     K      H
   0.317    0.134    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33088
Number of Hits to DB: 45,992,396
Number of extensions: 1299226
Number of successful extensions: 3834
Number of sequences better than 1.0e-05: 15
Number of HSP's gapped: 3791
Number of HSP's successfully gapped: 18
Length of query: 376
Length of database: 17,681,374
Length adjustment: 104
Effective length of query: 272
Effective length of database: 14,240,222
Effective search space: 3873340384
Effective search space used: 3873340384
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-008115
         (1128 letters)

Database: RefSeq49_CP.fasta 
           33,336 sequences; 18,874,504 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_001003115.1| cathepsin L1 precursor [Canis lupus familiar...   619   0.0  
Alignment   gi|XP_541257.2| PREDICTED: similar to Cathepsin L precursor (Ma...   483   e-139
Alignment   gi|XP_855060.1| PREDICTED: similar to Cathepsin L2 precursor (C...   403   e-116
Alignment   gi|NP_001029168.1| cathepsin K precursor [Canis lupus familiari...   311   1e-85
Alignment   gi|NP_001002938.1| cathepsin S precursor [Canis lupus familiari...   295   7e-80
Alignment   gi|XP_536212.2| PREDICTED: similar to Cathepsin H precursor [Ca...   196   4e-50
Alignment   gi|XP_533219.2| PREDICTED: similar to Cathepsin F precursor (CA...   185   6e-47
Alignment   gi|XP_540846.2| PREDICTED: similar to cathepsin W preproprotein...   129   4e-30
Alignment   gi|XP_539782.2| PREDICTED: similar to Cathepsin O precursor [Ca...   125   6e-29
Alignment   gi|NP_001182763.1| dipeptidyl peptidase 1 [Canis lupus familiar...   110   3e-24

>ref|NP_001003115.1| cathepsin L1 precursor [Canis lupus familiaris].
          Length = 333

 Score =  619 bits (1596), Expect(2) = 0.0
 Identities = 288/318 (90%), Positives = 304/318 (95%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M PSLFLTALCLGIASAAPK DQ+L+A WY+WKATH RLYGMNEEGWRRAVWEKNMKMIE
Sbjct: 1    MNPSLFLTALCLGIASAAPKFDQSLNAQWYQWKATHRRLYGMNEEGWRRAVWEKNMKMIE 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
            LHN+EYSQGKHGF+MAMNAFGDMTNEEFRQVMNGFQNQKHKKGK+F E L  E+PKSVDW
Sbjct: 61   LHNREYSQGKHGFTMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKMFQEPLFAEIPKSVDW 120

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
            REKGYVT VKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSR QGN+GCNG
Sbjct: 121  REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNEGCNG 180

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV 816
            GLMDNAF+YVKDNGGLD+EESYPYLGR+T +C YKPECSAANDTGFVD+PQREKALMKAV
Sbjct: 181  GLMDNAFRYVKDNGGLDSEESYPYLGRDTETCNYKPECSAANDTGFVDLPQREKALMKAV 240

Query: 817  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 996
            AT+GPISVAIDAGH SFQFYKSGIY+DPDCSSKDLDHGVLVVGYGFEGTDSN +KFWIVK
Sbjct: 241  ATLGPISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSN-NKFWIVK 299

Query: 997  NSWGPEWGWNGYVKMAKD 1050
            NSWGPEWGWNGYVKMAKD
Sbjct: 300  NSWGPEWGWNGYVKMAKD 317



 Score = 36.2 bits (82), Expect(2) = 0.0
 Identities = 14/18 (77%), Positives = 17/18 (94%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            + +NNHCGI+TAASYPTV
Sbjct: 316  KDQNNHCGIATAASYPTV 333


>ref|XP_541257.2| PREDICTED: similar to Cathepsin L precursor (Major excreted protein)
            (MEP) [Canis familiaris].
          Length = 333

 Score =  483 bits (1244), Expect(2) = e-139
 Identities = 229/318 (72%), Positives = 259/318 (81%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M PSLFL ALCLGIASAAP+ D +LDA W +WK  HG+LY  +EEGWRR VWE+NM+MIE
Sbjct: 1    MHPSLFLAALCLGIASAAPQQDHSLDAHWSQWKEAHGKLYDKDEEGWRRTVWERNMEMIE 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
             HNQEYSQG+H F++AMNAFGDMTNEEF+QV+N F+ QKHKKGKVF   L  EVP SVDW
Sbjct: 61   QHNQEYSQGEHSFTLAMNAFGDMTNEEFKQVLNDFKIQKHKKGKVFPAPLFAEVPSSVDW 120

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
            RE+GYVT VK+QGQC  CWAFSATGALEGQMFRKTGKLVSLSEQNLVDCS  QGN+GCNG
Sbjct: 121  REQGYVTPVKDQGQCLGCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSWSQGNRGCNG 180

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV 816
            GLM+ AFQYVKDNGGLD+EESYPYL R    C Y+PE SAAN T F  I   E  LM  V
Sbjct: 181  GLMEYAFQYVKDNGGLDSEESYPYLAR-NEPCKYRPEKSAANVTAFWPILNEEDGLMTTV 239

Query: 817  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 996
            ATVGP+S A+D+   SFQFYK GIYYDP CS+K L+HGVLVVGYGFEG +S++ K+WIVK
Sbjct: 240  ATVGPVSAAVDSSPQSFQFYKKGIYYDPKCSNKLLNHGVLVVGYGFEGAESDNKKYWIVK 299

Query: 997  NSWGPEWGWNGYVKMAKD 1050
            NSWG  WG  GY+ +AKD
Sbjct: 300  NSWGTNWGMQGYMLLAKD 317



 Score = 32.0 bits (71), Expect(2) = e-139
 Identities = 12/18 (66%), Positives = 15/18 (83%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            + R+NHCGI+T ASYP V
Sbjct: 316  KDRDNHCGIATRASYPVV 333


>ref|XP_855060.1| PREDICTED: similar to Cathepsin L2 precursor (Cathepsin V) (Cathepsin
            U) [Canis familiaris].
          Length = 289

 Score =  403 bits (1035), Expect(2) = e-116
 Identities = 207/305 (67%), Positives = 227/305 (74%)
 Frame = +1

Query: 133  GIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIELHNQEYSQGKHG 312
            GI SAAPKLDQ+L+A WY+WKA H RLY MNEEGWRRAVWEKNMKMIELHN+EYSQGKHG
Sbjct: 10   GIVSAAPKLDQSLNAQWYQWKAMH-RLYAMNEEGWRRAVWEKNMKMIELHNREYSQGKHG 68

Query: 313  FSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDWREKGYVTAVKNQ 492
            F+MAMNAFG MTNEEFRQVMNGFQNQKHKKGKVF E L  E+PKSVDWREKGYVT VKNQ
Sbjct: 69   FTMAMNAFGYMTNEEFRQVMNGFQNQKHKKGKVFQEPLFAEIPKSVDWREKGYVTPVKNQ 128

Query: 493  GQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYVKD 672
            G CGSCWAFSATG L+GQMF+KTGKL      NLVDC + QGN+GCNGGLMDNAFQYVKD
Sbjct: 129  GHCGSCWAFSATGDLKGQMFQKTGKL------NLVDCYQAQGNKGCNGGLMDNAFQYVKD 182

Query: 673  NGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAVATVGPISVAIDA 852
            NGGLD+EE Y YLGR+T++  YKPECSA              A+  A  T      +++ 
Sbjct: 183  NGGLDSEECYLYLGRDTDTYNYKPECSA--------------AMTLASWT------SLNG 222

Query: 853  GHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGWNGY 1032
                 Q  +S  Y               VVGYGFEGTDSN +K WIVKNSWG EWGWNGY
Sbjct: 223  RRLQQQRSRSWCYG--------------VVGYGFEGTDSN-NKLWIVKNSWGTEWGWNGY 267

Query: 1033 VKMAK 1047
            VK AK
Sbjct: 268  VKTAK 272



 Score = 35.8 bits (81), Expect(2) = e-116
 Identities = 14/16 (87%), Positives = 16/16 (100%)
 Frame = +3

Query: 1053 RNNHCGISTAASYPTV 1100
            +NNHCGI+TAASYPTV
Sbjct: 274  QNNHCGIATAASYPTV 289


>ref|NP_001029168.1| cathepsin K precursor [Canis lupus familiaris].
          Length = 330

 Score =  311 bits (797), Expect(2) = 1e-85
 Identities = 161/314 (51%), Positives = 208/314 (66%), Gaps = 5/314 (1%)
 Frame = +1

Query: 124  LCLGIASAAPKLDQNLDADWYKWKATHGRLYGMN-EEGWRRAVWEKNMKMIELHNQEYSQ 300
            L L +AS A   ++ LD  W  WK T+ + Y    +E  RR +WEKN+K I +HN E S 
Sbjct: 8    LLLPMASFALYPEEILDTQWDLWKKTYRKQYNSKVDELSRRLIWEKNLKHISIHNLEASL 67

Query: 301  GKHGFSMAMNAFGDMTNEEFRQVMNGFQ---NQKHKKGKVFHESLVLEVPKSVDWREKGY 471
            G H + +AMN  GDMT+EE  Q M G +   +       ++        P SVD+R+KGY
Sbjct: 68   GVHTYELAMNHLGDMTSEEVVQKMTGLKVPPSHSRSNDTLYIPDWESRAPDSVDYRKKGY 127

Query: 472  VTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDN 651
            VT VKNQGQCGSCWAFS+ GALEGQ+ +KTGKL++LS QNLVDC     N GC GG M N
Sbjct: 128  VTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC--VSENDGCGGGYMTN 185

Query: 652  AFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQ-REKALMKAVATVG 828
            AFQYV+ N G+D+E++YPY+G++  SC Y P   AA   G+ +IP+  EKAL +AVA VG
Sbjct: 186  AFQYVQKNRGIDSEDAYPYVGQD-ESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVG 244

Query: 829  PISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWG 1008
            PISVAIDA  +SFQFY  G+YYD +C+S +L+H VL VGYG +      +K WI+KNSWG
Sbjct: 245  PISVAIDASLTSFQFYSKGVYYDENCNSDNLNHAVLAVGYGIQ----KGNKHWIIKNSWG 300

Query: 1009 PEWGWNGYVKMAKD 1050
              WG  GY+ MA++
Sbjct: 301  ENWGNKGYILMARN 314



 Score = 24.6 bits (52), Expect(2) = 1e-85
 Identities = 9/16 (56%), Positives = 12/16 (75%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYP 1094
            R +NN CGI+  AS+P
Sbjct: 313  RNKNNACGIANLASFP 328


>ref|NP_001002938.1| cathepsin S precursor [Canis lupus familiaris].
          Length = 331

 Score =  295 bits (754), Expect = 7e-80
 Identities = 160/338 (47%), Positives = 209/338 (61%), Gaps = 6/338 (1%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGM-NEEGWRRAVWEKNMKMI 273
            MK  + L  LC   A A    D  LD  W  WK T+ + Y   NEE  RR +WEKN+K +
Sbjct: 1    MKWLVGLLPLC-SYAVAQVHKDPTLDHHWNLWKKTYSKQYKEENEEVARRLIWEKNLKFV 59

Query: 274  ELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQ-NQKHKKGKVFHESLVLEVPKSV 450
             LHN E+S G H + + MN  GDMT EE   +M   +   + ++   +  +   ++P SV
Sbjct: 60   MLHNLEHSMGMHSYDLGMNHLGDMTGEEVISLMGSLRVPSQWQRNVTYRSNSNQKLPDSV 119

Query: 451  DWREKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ-GNQG 627
            DWREKG VT VK QG CG+CWAFSA GALE Q+  KTGKLVSLS QNLVDCS  + GN+G
Sbjct: 120  DWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKG 179

Query: 628  CNGGLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIP-QREKAL 804
            CNGG M  AFQY+ DN G+D+E SYPY       C Y  +  AA  + + ++P   E AL
Sbjct: 180  CNGGFMTTAFQYIIDNNGIDSEASYPYKAM-NGKCRYDSKKRAATCSKYTELPFGSEDAL 238

Query: 805  MKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKF 984
             +AVA  GP+SVAIDA H SF  Y+SG+YY+P C +++++HGVLVVGYG    + N   +
Sbjct: 239  KEAVANKGPVSVAIDASHYSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----NLNGKDY 293

Query: 985  WIVKNSWGPEWGWNGYVKMAKDP--ETTTVEFPQQPAI 1092
            W+VKNSWG  +G  GY++MA++         +P  P I
Sbjct: 294  WLVKNSWGLNFGDQGYIRMARNSGNHCGIASYPSYPEI 331


>ref|XP_536212.2| PREDICTED: similar to Cathepsin H precursor [Canis familiaris].
          Length = 304

 Score =  196 bits (497), Expect = 4e-50
 Identities = 118/290 (40%), Positives = 159/290 (54%), Gaps = 8/290 (2%)
 Frame = +1

Query: 202  HGRLYGMNEEGWRRAVWEKNMKMIELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQ--VMN 375
            H + Y   E   R   +  N + I  HN     G H F M +N F DM   E +   + +
Sbjct: 10   HQKKYSSEEYLQRLQTFVGNWRKINAHNA----GNHTFKMGLNQFSDMNFAEIKHKYLWS 65

Query: 376  GFQNQKHKKGKVFHESLVLEVPKSVDWREKG-YVTAVKNQGQCGSCWAFSATGALEGQMF 552
              QN    KG     +     P  VDWR+KG +V+ VKNQG CGSCW FS TGALE  + 
Sbjct: 66   EPQNCSATKGNYLRGTG--PYPPFVDWRKKGKFVSPVKNQGSCGSCWTFSTTGALESAIA 123

Query: 553  RKTGKLVSLSEQNLVDCSRPQGNQGCNG-GLMDNAFQYVKDNGGLDTEESYPYLGRETNS 729
             K+GKL+SL+EQ LVDC++   N GC G G    AF+Y++ N G+  E+SYPY G++   
Sbjct: 124  IKSGKLLSLAEQQLVDCAQNFNNHGCQGYGAPLQAFEYIRYNKGIMGEDSYPYKGQD-GD 182

Query: 730  CTYKPECSAA--NDTGFVDIPQREKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPD 903
            C Y+P  + A   D   + I   E+A+++AVA   P+S A +   S F  Y+ GIY    
Sbjct: 183  CKYQPSKAIAFVKDVANITI-NDEQAMVEAVALYNPVSFAFEV-TSDFMMYRKGIYSSTS 240

Query: 904  C--SSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGWNGYVKMAK 1047
            C  +   ++H VL VGYG    + N   +WIVKNSWGP+WG NGY  M +
Sbjct: 241  CHKTPDKVNHAVLAVGYG----EQNGIPYWIVKNSWGPQWGMNGYFLMER 286


>ref|XP_533219.2| PREDICTED: similar to Cathepsin F precursor (CATSF) [Canis
            familiaris].
          Length = 442

 Score =  185 bits (470), Expect = 6e-47
 Identities = 111/284 (39%), Positives = 157/284 (55%), Gaps = 6/284 (2%)
 Frame = +1

Query: 199  THGRLYGMNEEG-WRRAVWEKNM-KMIELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVM 372
            T+ R Y   EE  WR +V+  NM +  ++   +    ++G +     F D+T EEFR + 
Sbjct: 150  TYNRTYETKEEAEWRMSVFSNNMVRAQKIQALDRGTAQYGITK----FSDLTEEEFRTIY 205

Query: 373  NG--FQNQKHKKGKVFHESLVLEVPKSVDWREKGYVTAVKNQGQCGSCWAFSATGALEGQ 546
                 +  + KK ++         P   DWR KG VT VK+QG CGSCWAFS TG +EGQ
Sbjct: 206  LNPLLRENRGKKMRLAKSISDHAPPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQ 265

Query: 547  MFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYLGRETN 726
             F K G L+SLSEQ L+DC +   ++ C GGL  NA+  +   GGL+TE+ Y Y G    
Sbjct: 266  WFLKEGTLLSLSEQELLDCDKV--DKACLGGLPSNAYSAIMTLGGLETEDDYSYQG-HLQ 322

Query: 727  SCTYKPECSAANDTGFVDIPQREKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYD--P 900
            +C++  + +       +++ Q E+ L   +A  GPISVAI+A     QFY+ GI +   P
Sbjct: 323  ACSFSAKKARVYINDSMELSQNEQKLAAWLAKKGPISVAINA--FGMQFYRHGISHPLRP 380

Query: 901  DCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGWNGY 1032
             CS   +DH VL+VGYG    + +   FW +KNSWG +WG  GY
Sbjct: 381  LCSPWLIDHAVLLVGYG----NRSGIPFWAIKNSWGTDWGEEGY 420


>ref|XP_540846.2| PREDICTED: similar to cathepsin W preproprotein [Canis familiaris].
          Length = 374

 Score =  129 bits (325), Expect = 4e-30
 Identities = 98/313 (31%), Positives = 147/313 (46%), Gaps = 27/313 (8%)
 Frame = +1

Query: 202  HGRLYGMNEEGWRRA-VWEKNMKMIE-LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMN 375
            + R Y   EE  RR  ++  N+   + L +++    + G    +  F D+T EEF Q   
Sbjct: 49   YNRSYSNPEEYARRLDIFAHNLAQAQQLEDEDLGTAEFG----VTPFSDLTEEEFGQ--- 101

Query: 376  GFQNQKHKKG-------KVFHESLVLEVPKSVDWRE-KGYVTAVKNQGQCGSCWAFSATG 531
             F   +   G       KV  E     VP + DWR+  G ++ +K QG C  CWA +A G
Sbjct: 102  -FYGHQRMAGEAPSVGRKVESEEWGEPVPPTCDWRKLPGIISPIKQQGNCRCCWAMAAAG 160

Query: 532  ALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYL 711
             +E     +  + V +S Q L+DC R     GC GG   +AF  V +N GL + + YP+L
Sbjct: 161  NIEALWGIRYHQPVEVSVQELLDCGR--CGDGCKGGFTWDAFITVLNNSGLASAKDYPFL 218

Query: 712  GR-ETNSCTYKPECSAANDTGFVDIPQREKALMKAVATVGPISVAIDAGHSSFQFYKSGI 888
            G  + + C  K     A    F+ +   E+A+   +AT GPI+V I+      Q Y+ G+
Sbjct: 219  GNTKPHRCLAKKYKKVAWIQDFIMLQGNEQAIAWYLATKGPITVTINM--KLLQHYQKGV 276

Query: 889  YY--DPDCSSKDLDHGVLVVGYG---------FEGTDS-----NSSKFWIVKNSWGPEWG 1020
                   C  + +DH VL+VG+G          EG  S     +   +WI+KNSWG EWG
Sbjct: 277  IQATHTTCDPQRVDHSVLLVGFGKSKSVAGKQAEGGSSRPRPHHPIPYWILKNSWGAEWG 336

Query: 1021 WNGYVKMAKDPET 1059
              GY ++ +   T
Sbjct: 337  EEGYFRLHRGNNT 349


>ref|XP_539782.2| PREDICTED: similar to Cathepsin O precursor [Canis familiaris].
          Length = 518

 Score =  125 bits (315), Expect = 6e-29
 Identities = 83/246 (33%), Positives = 123/246 (50%), Gaps = 7/246 (2%)
 Frame = +1

Query: 325  MNAFGDMTNEEFRQVMNGFQNQKHKK--GKVFHESLVLEVPKSVDWREKGYVTAVKNQGQ 498
            +N F  ++ EEF+ +    +  +  +   +V      + +P   DWR+K  VT V+NQ  
Sbjct: 264  INQFSYLSPEEFKAIYLRSKPSRSPRYPAEVRTSIRNVSLPLRFDWRDKRVVTQVRNQQT 323

Query: 499  CGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYV-KDN 675
            CG CWAFS  GA+E     K   L  +S Q ++DCS    N GC+GG   NA  ++ K  
Sbjct: 324  CGGCWAFSVVGAVESAYAIKGKPLADISVQQVIDCS--YNNYGCSGGSTLNALNWLNKTQ 381

Query: 676  GGLDTEESYPYLGRETNSCTYKPECSAANDTGF--VDIPQREKALMKAVATVGPISVAID 849
              L  +  YP+  +      +    S  +  G+   D   +E  + K + T GP+ V +D
Sbjct: 382  VKLVRDSEYPFKAQNGLCHYFSDSYSGFSIRGYSAYDFSDQEDEMAKVLLTFGPLVVVVD 441

Query: 850  AGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGWNG 1029
            A   S+Q Y  GI     CSS + +H VL+ G+   G    S+ +WIV+NSWG  WG +G
Sbjct: 442  A--VSWQDYLGGI-IQHHCSSGEANHAVLITGFDKIG----STPYWIVRNSWGSSWGVDG 494

Query: 1030 Y--VKM 1041
            Y  VKM
Sbjct: 495  YAHVKM 500


>ref|NP_001182763.1| dipeptidyl peptidase 1 [Canis lupus familiaris].
          Length = 459

 Score =  110 bits (274), Expect = 3e-24
 Identities = 85/243 (34%), Positives = 118/243 (48%), Gaps = 16/243 (6%)
 Frame = +1

Query: 415  HESLVLEVPKSVDWRE---KGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVS--L 579
            HE  +  +P S DWR      +V+ V+NQ  CGSC+AF++T  LE ++   T    +  L
Sbjct: 222  HEE-ISRLPTSWDWRNVRGTNFVSPVRNQASCGSCYAFASTAMLEARIRILTNNTQTPIL 280

Query: 580  SEQNLVDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYLGRET----NSCTYKPE 747
            S Q +V CS  Q  QGC GG           + GL  E  +PY G ++    N C     
Sbjct: 281  SPQEIVSCS--QYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYAGSDSPCKPNDCFRYYS 338

Query: 748  CSAANDTGFVDIPQREKALMKA-VATVGPISVAIDAGHSSFQFYKSGIYY-----DPDCS 909
                   GF       +ALMK  +   GP++VA +  +  F  Y+ GIYY     DP   
Sbjct: 339  SEYYYVGGFYGACN--EALMKLELVRHGPMAVAFEV-YDDFFHYQKGIYYHTGLRDPFNP 395

Query: 910  SKDLDHGVLVVGYGFEGTDSNSSK-FWIVKNSWGPEWGWNGYVKMAKDPETTTVEFPQQP 1086
             +  +H VL+VGYG   TDS S   +WIVKNSWG  WG +GY ++ +  +   +E     
Sbjct: 396  FELTNHAVLLVGYG---TDSASGMDYWIVKNSWGSRWGEDGYFRIRRGTDECAIESIAVA 452

Query: 1087 AIP 1095
            A P
Sbjct: 453  ATP 455


  Database: RefSeq49_CP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,874,504
  Number of sequences in database:  33,336
  
Lambda     K      H
   0.317    0.134    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33336
Number of Hits to DB: 48,019,535
Number of extensions: 1333050
Number of successful extensions: 3727
Number of sequences better than 1.0e-05: 15
Number of HSP's gapped: 3681
Number of HSP's successfully gapped: 22
Length of query: 376
Length of database: 18,874,504
Length adjustment: 104
Effective length of query: 272
Effective length of database: 15,407,560
Effective search space: 4190856320
Effective search space used: 4190856320
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-008115
         (1128 letters)

Database: RefSeq49_SP.fasta 
           24,897 sequences; 11,343,932 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_999057.1| cathepsin L1 precursor [Sus scrofa].                 674   0.0  
Alignment   gi|XP_003130681.1| PREDICTED: cathepsin L1-like [Sus scrofa].        529   e-153
Alignment   gi|NP_999467.1| cathepsin K precursor [Sus scrofa].                  310   2e-85
Alignment   gi|XP_001929706.1| PREDICTED: cathepsin S [Sus scrofa].              298   3e-81
Alignment   gi|XP_003355243.1| PREDICTED: cathepsin S-like [Sus scrofa].         298   3e-81
Alignment   gi|NP_999094.1| pro-cathepsin H precursor [Sus scrofa].              208   5e-54
Alignment   gi|XP_003122543.2| PREDICTED: cathepsin F [Sus scrofa].              198   5e-51
Alignment   gi|XP_003122571.1| PREDICTED: cathepsin W-like [Sus scrofa].         145   3e-35
Alignment   gi|XP_003129789.1| PREDICTED: dipeptidyl peptidase 1-like [Sus ...   109   3e-24
Alignment   gi|XP_003129045.2| PREDICTED: tryptophan 2,3-dioxygenase [Sus s...   104   1e-22

>ref|NP_999057.1| cathepsin L1 precursor [Sus scrofa].
          Length = 334

 Score =  674 bits (1740), Expect(2) = 0.0
 Identities = 318/318 (100%), Positives = 318/318 (100%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE
Sbjct: 1    MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
            LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW
Sbjct: 61   LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 120

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
            REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
Sbjct: 121  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV 816
            GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV
Sbjct: 181  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV 240

Query: 817  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 996
            ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK
Sbjct: 241  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 300

Query: 997  NSWGPEWGWNGYVKMAKD 1050
            NSWGPEWGWNGYVKMAKD
Sbjct: 301  NSWGPEWGWNGYVKMAKD 318



 Score = 37.4 bits (85), Expect(2) = 0.0
 Identities = 15/18 (83%), Positives = 17/18 (94%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            + +NNHCGISTAASYPTV
Sbjct: 317  KDQNNHCGISTAASYPTV 334


>ref|XP_003130681.1| PREDICTED: cathepsin L1-like [Sus scrofa].
          Length = 332

 Score =  529 bits (1363), Expect(2) = e-153
 Identities = 247/318 (77%), Positives = 277/318 (87%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M PSL L A CLGIASAAP+ D +LDADWYKWKATH +LYG+NEEG RRA+WEKNMKMIE
Sbjct: 1    MNPSLLLAAFCLGIASAAPRHDHSLDADWYKWKATHRKLYGLNEEGRRRAIWEKNMKMIE 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
             HN E+ QGKH F+MAMNAFGDMTNEEFR+ MNGFQNQKHKKGKVF ++     P SVDW
Sbjct: 61   RHNWEHRQGKHSFTMAMNAFGDMTNEEFRKTMNGFQNQKHKKGKVFLDAGSALTPHSVDW 120

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
            REKGYVTAVKNQG CGSCWAFSATGALEGQMFRKT KL+SLSEQNLVDCS P+GN+GCNG
Sbjct: 121  REKGYVTAVKNQGHCGSCWAFSATGALEGQMFRKTSKLISLSEQNLVDCSWPEGNEGCNG 180

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV 816
            GLMDNAFQY+KDNGGLD+EESYPY G++  SC YKP+ SAANDTG+VDIP++EKALMKAV
Sbjct: 181  GLMDNAFQYIKDNGGLDSEESYPYFGKD-GSCKYKPQSSAANDTGYVDIPKQEKALMKAV 239

Query: 817  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 996
            ATVGPISV IDA H SFQFY +GIY++P CSS+DLDHGVLVVGYG EG  SN +K+W+VK
Sbjct: 240  ATVGPISVGIDASHESFQFYSTGIYFEPQCSSEDLDHGVLVVGYGVEGAHSN-NKYWLVK 298

Query: 997  NSWGPEWGWNGYVKMAKD 1050
            NSWG  WG +GY+KM KD
Sbjct: 299  NSWGNTWGMDGYIKMTKD 316



 Score = 32.3 bits (72), Expect(2) = e-153
 Identities = 12/18 (66%), Positives = 15/18 (83%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            + +NNHCGI+T ASYP V
Sbjct: 315  KDQNNHCGIATMASYPVV 332


>ref|NP_999467.1| cathepsin K precursor [Sus scrofa].
          Length = 330

 Score =  310 bits (794), Expect(2) = 2e-85
 Identities = 158/314 (50%), Positives = 207/314 (65%), Gaps = 5/314 (1%)
 Frame = +1

Query: 124  LCLGIASAAPKLDQNLDADWYKWKATHGRLYGMN-EEGWRRAVWEKNMKMIELHNQEYSQ 300
            L L + S+A   ++ LD  W  WK T+ + Y    +E  RR +WEKN+K I +HN E S 
Sbjct: 8    LLLPVMSSALYPEEILDTQWELWKKTYRKQYNSKVDEISRRLIWEKNLKHISIHNLEASL 67

Query: 301  GKHGFSMAMNAFGDMTNEEFRQVMNGFQ---NQKHKKGKVFHESLVLEVPKSVDWREKGY 471
            G H + +AMN  GDMT+EE  Q M G +   +       ++        P S+D+R+KGY
Sbjct: 68   GVHTYELAMNHLGDMTSEEVVQKMTGLKVPPSHSRSNDTLYIPDWEGRTPDSIDYRKKGY 127

Query: 472  VTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDN 651
            VT VKNQGQCGSCWAFS+ GALEGQ+ +KTGKL++LS QNLVDC     N GC GG M N
Sbjct: 128  VTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC--VSENDGCGGGYMTN 185

Query: 652  AFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQ-REKALMKAVATVG 828
            AFQYV+ N G+D+E++YPY+G++ N C Y P   AA   G+ +IP+  EKAL +AVA VG
Sbjct: 186  AFQYVQKNRGIDSEDAYPYVGQDEN-CMYNPTGKAAKCRGYREIPEGNEKALKRAVARVG 244

Query: 829  PISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWG 1008
            P+SVAIDA  +SFQFY  G+YYD +C+S +L+H VL VGYG +       K WI+KNSWG
Sbjct: 245  PVSVAIDASLTSFQFYSKGVYYDENCNSDNLNHAVLAVGYGIQ----KGKKHWIIKNSWG 300

Query: 1009 PEWGWNGYVKMAKD 1050
              WG  GY+ MA++
Sbjct: 301  ENWGNKGYILMARN 314



 Score = 24.6 bits (52), Expect(2) = 2e-85
 Identities = 9/16 (56%), Positives = 12/16 (75%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYP 1094
            R +NN CGI+  AS+P
Sbjct: 313  RNKNNACGIANLASFP 328


>ref|XP_001929706.1| PREDICTED: cathepsin S [Sus scrofa].
          Length = 331

 Score =  298 bits (764), Expect = 3e-81
 Identities = 164/338 (48%), Positives = 215/338 (63%), Gaps = 6/338 (1%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYG-MNEEGWRRAVWEKNMKMI 273
            MK  +++  LC   A A    D  LD  W  WK T+G+ Y   NEE  RR +WEKN+K +
Sbjct: 1    MKCLVWVLLLCSS-AMAQLHRDPTLDRHWDLWKKTYGKQYKEKNEEVARRLIWEKNLKTV 59

Query: 274  ELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLE-VPKSV 450
             LHN E+S G H + + MN  GDMT+EE   +M+  +        V ++S   + +P S+
Sbjct: 60   MLHNLEHSMGMHSYDLGMNHLGDMTSEEVISLMSCVRVPSQWPRNVTYKSNPNQKLPDSM 119

Query: 451  DWREKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ-GNQG 627
            DWREKG VT VK QG CGSCWAFSA GALE Q+  KTG+LVSLS QNLVDCS  +  N+G
Sbjct: 120  DWREKGCVTEVKYQGSCGSCWAFSAVGALEAQVKMKTGRLVSLSAQNLVDCSTEKYRNKG 179

Query: 628  CNGGLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIP-QREKAL 804
            CNGG M  AFQY+ DN G+D+E SYPY   +   C Y  +  AA  + + ++P   E AL
Sbjct: 180  CNGGFMTEAFQYIIDNNGIDSEASYPYKAVD-GKCKYDSKNRAATCSRYTELPFADEYAL 238

Query: 805  MKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKF 984
             +AVA  GP+SVAIDA HSSF FY+SG+YYDP C +++++HGVLVVGYG    + N   +
Sbjct: 239  KEAVANKGPVSVAIDAKHSSFFFYRSGVYYDPSC-TQNVNHGVLVVGYG----NLNGKDY 293

Query: 985  WIVKNSWGPEWGWNGYVKMAKDPET--TTVEFPQQPAI 1092
            W+VKNSWG  +G  GY++MA++ E       +P  P I
Sbjct: 294  WLVKNSWGLNFGDGGYIRMARNSENHCGIANYPSYPEI 331


>ref|XP_003355243.1| PREDICTED: cathepsin S-like [Sus scrofa].
          Length = 331

 Score =  298 bits (764), Expect = 3e-81
 Identities = 164/338 (48%), Positives = 215/338 (63%), Gaps = 6/338 (1%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYG-MNEEGWRRAVWEKNMKMI 273
            MK  +++  LC   A A    D  LD  W  WK T+G+ Y   NEE  RR +WEKN+K +
Sbjct: 1    MKCLVWVLLLCSS-AMAQLHRDPTLDRHWDLWKKTYGKQYKEKNEEVARRLIWEKNLKTV 59

Query: 274  ELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLE-VPKSV 450
             LHN E+S G H + + MN  GDMT+EE   +M+  +        V ++S   + +P S+
Sbjct: 60   MLHNLEHSMGMHSYDLGMNHLGDMTSEEVISLMSCVRVPSQWPRNVTYKSNPNQKLPDSM 119

Query: 451  DWREKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ-GNQG 627
            DWREKG VT VK QG CGSCWAFSA GALE Q+  KTG+LVSLS QNLVDCS  +  N+G
Sbjct: 120  DWREKGCVTEVKYQGSCGSCWAFSAVGALEAQVKMKTGRLVSLSAQNLVDCSTEKYRNKG 179

Query: 628  CNGGLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIP-QREKAL 804
            CNGG M  AFQY+ DN G+D+E SYPY   +   C Y  +  AA  + + ++P   E AL
Sbjct: 180  CNGGFMTEAFQYIIDNNGIDSEASYPYKAVD-GKCKYDSKNRAATCSRYTELPFADEYAL 238

Query: 805  MKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKF 984
             +AVA  GP+SVAIDA HSSF FY+SG+YYDP C +++++HGVLVVGYG    + N   +
Sbjct: 239  KEAVANKGPVSVAIDAKHSSFFFYRSGVYYDPSC-TQNVNHGVLVVGYG----NLNGKDY 293

Query: 985  WIVKNSWGPEWGWNGYVKMAKDPET--TTVEFPQQPAI 1092
            W+VKNSWG  +G  GY++MA++ E       +P  P I
Sbjct: 294  WLVKNSWGLNFGDGGYIRMARNSENHCGIANYPSYPEI 331


>ref|NP_999094.1| pro-cathepsin H precursor [Sus scrofa].
          Length = 335

 Score =  208 bits (529), Expect = 5e-54
 Identities = 115/287 (40%), Positives = 164/287 (57%), Gaps = 6/287 (2%)
 Frame = +1

Query: 190  WKATHGRLYGMNEEGWRRAVWEKNMKMIELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQ- 366
            W   H + Y + E   R  V+  N + I  HN     G H F + +N F DM+ +E R  
Sbjct: 38   WMVQHQKKYSLEEYHHRLQVFVSNWRKINAHNA----GNHTFKLGLNQFSDMSFDEIRHK 93

Query: 367  -VMNGFQNQKHKKGKVFHESLVLEVPKSVDWREKG-YVTAVKNQGQCGSCWAFSATGALE 540
             + +  QN    KG     +     P S+DWR+KG +V+ VKNQG CGSCW FS TGALE
Sbjct: 94   YLWSEPQNCSATKGNYLRGTG--PYPPSMDWRKKGNFVSPVKNQGSCGSCWTFSTTGALE 151

Query: 541  GQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYLGRE 720
              +   TGK++SL+EQ LVDC++   N GC GGL   AF+Y++ N G+  E++YPY G++
Sbjct: 152  SAVAIATGKMLSLAEQQLVDCAQNFNNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQD 211

Query: 721  TNSCTYKPECSAANDTGFVDIPQR-EKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYD 897
             + C ++P+ + A      +I    E+A+++AVA   P+S A +   + F  Y+ GIY  
Sbjct: 212  -DHCKFQPDKAIAFVKDVANITMNDEEAMVEAVALYNPVSFAFEV-TNDFLMYRKGIYSS 269

Query: 898  PDC--SSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGWNGY 1032
              C  +   ++H VL VGYG    + N   +WIVKNSWGP+WG NGY
Sbjct: 270  TSCHKTPDKVNHAVLAVGYG----EENGIPYWIVKNSWGPQWGMNGY 312


>ref|XP_003122543.2| PREDICTED: cathepsin F [Sus scrofa].
          Length = 490

 Score =  198 bits (503), Expect = 5e-51
 Identities = 116/283 (40%), Positives = 164/283 (57%), Gaps = 5/283 (1%)
 Frame = +1

Query: 199  THGRLYGMNEEG-WRRAVWEKNM-KMIELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQV- 369
            T+ R Y   EE  WR +V+  NM +  ++   +    ++G    +  F D+T EEFR + 
Sbjct: 199  TYNRTYDTKEEARWRMSVFANNMVRAQKIQALDTGTARYG----VTKFSDLTEEEFRTIY 254

Query: 370  MNGFQNQKHKKGKVFHESLVLEVPKSVDWREKGYVTAVKNQGQCGSCWAFSATGALEGQM 549
            +N    ++  +     +S+    P   DWR+KG VT VK+QG CGSCWAFS TG +EGQ 
Sbjct: 255  LNPLLQEEPGRKMRLAKSVSSLPPPEWDWRKKGAVTKVKDQGMCGSCWAFSVTGNVEGQW 314

Query: 550  FRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYLGRETNS 729
            F K G L+SLSEQ L+DC +   ++GC GGL  NA+  +K  GGL+TEE Y Y G    +
Sbjct: 315  FLKQGTLLSLSEQELLDCDKV--DKGCMGGLPSNAYSAIKTLGGLETEEDYSYRG-HLQT 371

Query: 730  CTYKPECSAANDTGFVDIPQREKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYD--PD 903
            C++  E +       V++ Q E+ L   +A  GPISVAI+A     QFY+ GI +   P 
Sbjct: 372  CSFNAEKAKVYINDSVELSQNEQKLAAWLAEKGPISVAINA--FGMQFYRHGISHPLRPL 429

Query: 904  CSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGWNGY 1032
            CS   +DH VL+VGYG    + +++ FW +KNSWG +WG  GY
Sbjct: 430  CSPWLIDHAVLLVGYG----NRSATPFWAIKNSWGTDWGEEGY 468


>ref|XP_003122571.1| PREDICTED: cathepsin W-like [Sus scrofa].
          Length = 367

 Score =  145 bits (367), Expect = 3e-35
 Identities = 105/302 (34%), Positives = 155/302 (51%), Gaps = 16/302 (5%)
 Frame = +1

Query: 202  HGRLYGMNEEGWRRA-VWEKNM-KMIELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMN 375
            + R Y    E  RR  ++ +N+ K   L  ++    + G    +  F D+T EEF Q+  
Sbjct: 49   YNRSYSNPAEHARRLDIFAQNLAKAQRLQEEDLGTAEFG----VTPFSDLTEEEFGQLHG 104

Query: 376  ---GFQNQKHKKGKVFHESLVLEVPKSVDWREK-GYVTAVKNQGQCGSCWAFSATGALEG 543
               G         KV  E     VP+S DWR+K G ++A+K+Q  C  CWA +A   +E 
Sbjct: 105  HHWGAGKAPSMGIKVGSEESGETVPQSCDWRKKPGVISAIKHQKDCNCCWAMAAVDNVEA 164

Query: 544  QMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYLGR-E 720
            Q   K  + V LS Q ++DC R  GN GCNGG + +AF  V +  GL +E+ YPY G  +
Sbjct: 165  QWAIKYHQAVQLSVQQVLDCDR-CGN-GCNGGFVWDAFLTVLNTSGLASEQDYPYKGTVK 222

Query: 721  TNSCTYKPECSAANDTGFVDIPQREKALMKAVATVGPISVAIDAGHSSFQFYKSGIY--Y 894
            T+ C  K     A    F+ +   E+++ + +AT GPI+V I+AG    Q YK G+    
Sbjct: 223  THRCLAKQHRKVAWIQDFLMLQFCEQSIARYLATEGPITVTINAG--LLQQYKRGVIRAT 280

Query: 895  DPDCSSKDLDHGVLVVGYG----FEG---TDSNSSKFWIVKNSWGPEWGWNGYVKMAKDP 1053
               C    ++H VL+VG+G     EG      +S  +WI+KNSWGP+WG  GY ++ +  
Sbjct: 281  PATCDPHLVNHSVLLVGFGKSKSVEGRRPRPGHSIPYWILKNSWGPDWGEEGYFRLHRGS 340

Query: 1054 ET 1059
             T
Sbjct: 341  NT 342


>ref|XP_003129789.1| PREDICTED: dipeptidyl peptidase 1-like [Sus scrofa].
          Length = 463

 Score =  109 bits (272), Expect = 3e-24
 Identities = 80/238 (33%), Positives = 119/238 (50%), Gaps = 16/238 (6%)
 Frame = +1

Query: 430  LEVPKSVDWRE---KGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVS--LSEQNL 594
            L +P S DWR      +VT V+NQ  CGSC++F++ G +E ++   T    +  LS Q +
Sbjct: 229  LHLPASWDWRNVRGTNFVTPVRNQASCGSCYSFASMGMMEARIRILTNNTQTPILSPQEV 288

Query: 595  VDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGF 774
            V CS  Q  QGC GG           + GL  E  +PY G ++  CT K  C     + +
Sbjct: 289  VSCS--QYAQGCAGGFPYLIAGKYAQDFGLVEEACFPYTGTDS-PCTVKEGCFRYYSSEY 345

Query: 775  VDIPQR----EKALMKA-VATVGPISVAIDAGHSSFQFYKSGIYY-----DPDCSSKDLD 924
              +        +ALMK  +   GP++VA +  +  F  Y+ GIY+     DP    +  +
Sbjct: 346  HYVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYRKGIYHHTGLRDPFNPFELTN 404

Query: 925  HGVLVVGYGFEGTD-SNSSKFWIVKNSWGPEWGWNGYVKMAKDPETTTVEFPQQPAIP 1095
            H VL+VGYG   TD ++   +WIVKNSWG  WG +GY ++ +  +   +E     A P
Sbjct: 405  HAVLLVGYG---TDLASGMDYWIVKNSWGTSWGEDGYFRIRRGTDECAIESIAVAATP 459


>ref|XP_003129045.2| PREDICTED: tryptophan 2,3-dioxygenase [Sus scrofa].
          Length = 411

 Score =  104 bits (259), Expect = 1e-22
 Identities = 70/188 (37%), Positives = 96/188 (51%), Gaps = 7/188 (3%)
 Frame = +1

Query: 499  CGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYV-KDN 675
            CG CWAFS   A+E     K   L  LS Q ++DCS    N GCNGG   NA  ++ K  
Sbjct: 219  CGGCWAFSVVSAVESAYAIKGQPLEVLSVQQVIDCS--YNNYGCNGGSTLNALYWLNKTQ 276

Query: 676  GGLDTEESYPYLGRETNSCTYKPECS----AANDTGFVDIPQREKALMKAVATVGPISVA 843
              + ++  YP+  +  N   +   CS    +  D    D   +E  + K + T+GP+ V 
Sbjct: 277  VKVVSDSEYPF--KAQNGLCHYFSCSHSGVSIKDYSAYDFSGQEDEMAKTLLTLGPLIVI 334

Query: 844  IDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGW 1023
            +DA   S+Q Y  GI     CSS + +H VLV G+   G    S+ +WIV+NSWG  WG 
Sbjct: 335  VDA--VSWQDYLGGI-IQHHCSSGEANHAVLVTGFDKTG----STPYWIVRNSWGSAWGI 387

Query: 1024 NGY--VKM 1041
            +GY  VKM
Sbjct: 388  DGYALVKM 395


  Database: RefSeq49_SP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 11,343,932
  Number of sequences in database:  24,897
  
Lambda     K      H
   0.317    0.134    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 24897
Number of Hits to DB: 29,596,169
Number of extensions: 828603
Number of successful extensions: 2404
Number of sequences better than 1.0e-05: 14
Number of HSP's gapped: 2357
Number of HSP's successfully gapped: 17
Length of query: 376
Length of database: 11,343,932
Length adjustment: 101
Effective length of query: 275
Effective length of database: 8,829,335
Effective search space: 2428067125
Effective search space used: 2428067125
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 34 (17.7 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-008115
         (1128 letters)

Database: RefSeq49_MP.fasta 
           30,036 sequences; 15,617,559 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_034114.1| cathepsin L1 preproprotein [Mus musculus].           516   e-147
Alignment   gi|NP_081620.2| cathepsin L-like 3 [Mus musculus].                   436   e-124
Alignment   gi|NP_954599.2| hypothetical protein LOC218275 [Mus musculus].       426   e-121
Alignment   gi|NP_835199.1| testin-2 precursor [Mus musculus].                   420   e-120
Alignment   gi|NP_071721.2| cathepsin M precursor [Mus musculus].                380   e-107
Alignment   gi|NP_067420.1| cathepsin 6 [Mus musculus].                          372   e-105
Alignment   gi|XP_922074.1| PREDICTED: cathepsin M-like [Mus musculus].          379   e-105
Alignment   gi|NP_062414.3| cathepsin 8 [Mus musculus].                          365   e-103
Alignment   gi|NP_064680.1| cathepsin R precursor [Mus musculus].                365   e-101
Alignment   gi|NP_036137.1| cathepsin J [Mus musculus].                          345   2e-97

>ref|NP_034114.1| cathepsin L1 preproprotein [Mus musculus].
          Length = 334

 Score =  516 bits (1330), Expect = e-147
 Identities = 235/314 (74%), Positives = 273/314 (86%)
 Frame = +1

Query: 109  LFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIELHNQ 288
            L L  LCLG A A PK DQ   A+W++WK+TH RLYG NEE WRRA+WEKNM+MI+LHN 
Sbjct: 5    LLLAVLCLGTALATPKFDQTFSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQLHNG 64

Query: 289  EYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDWREKG 468
            EYS G+HGFSM MNAFGDMTNEEFRQV+NG+++QKHKKG++F E L+L++PKSVDWREKG
Sbjct: 65   EYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHKKGRLFQEPLMLKIPKSVDWREKG 124

Query: 469  YVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMD 648
             VT VKNQGQCGSCWAFSA+G LEGQMF KTGKL+SLSEQNLVDCS  QGNQGCNGGLMD
Sbjct: 125  CVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMD 184

Query: 649  NAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAVATVG 828
             AFQY+K+NGGLD+EESYPY  ++  SC Y+ E + ANDTGFVDIPQ+EKALMKAVATVG
Sbjct: 185  FAFQYIKENGGLDSEESYPYEAKD-GSCKYRAEFAVANDTGFVDIPQQEKALMKAVATVG 243

Query: 829  PISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWG 1008
            PISVA+DA H S QFY SGIYY+P+CSSK+LDHGVL+VGYG+EGTDSN +K+W+VKNSWG
Sbjct: 244  PISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWG 303

Query: 1009 PEWGWNGYVKMAKD 1050
             EWG  GY+K+AKD
Sbjct: 304  SEWGMEGYIKIAKD 317


>ref|NP_081620.2| cathepsin L-like 3 [Mus musculus].
          Length = 331

 Score =  436 bits (1120), Expect(2) = e-124
 Identities = 212/319 (66%), Positives = 244/319 (76%), Gaps = 1/319 (0%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M P   L  LCLG+ SAAP  + +LDA W +WK  H + Y MN+EG +RAVWE N KMI+
Sbjct: 1    MTPVFLLATLCLGVVSAAPAHNPSLDAVWEEWKTKHKKTYNMNDEGQKRAVWENNKKMID 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKG-KVFHESLVLEVPKSVD 453
            LHN++Y +GKHGFS+ MNAFGD+TN EFR++M GFQ QK K   KVF E L+ +VPKSVD
Sbjct: 61   LHNEDYLKGKHGFSLEMNAFGDLTNTEFRELMTGFQGQKTKMMMKVFQEPLLGDVPKSVD 120

Query: 454  WREKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCN 633
            WR+ GYVT VK+QG CGSCWAFSA G+LEGQMFRKTGKLV LS QNLVDCS  QGNQGC+
Sbjct: 121  WRDHGYVTPVKDQGSCGSCWAFSAVGSLEGQMFRKTGKLVPLSVQNLVDCSWSQGNQGCD 180

Query: 634  GGLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKA 813
            GGL D AFQYVKDNGGLDT  SYPY      +C Y P+ SAA  TGFV++   E ALMKA
Sbjct: 181  GGLPDLAFQYVKDNGGLDTSVSYPYEAL-NGTCRYNPKNSAATVTGFVNVQSSEDALMKA 239

Query: 814  VATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIV 993
            VATVGPISV ID  H SFQFYK G+YY+PDCSS  LDH VLVVGYG E   S+  K+W+V
Sbjct: 240  VATVGPISVGIDTKHKSFQFYKEGMYYEPDCSSTVLDHAVLVVGYGEE---SDGRKYWLV 296

Query: 994  KNSWGPEWGWNGYVKMAKD 1050
            KNSWG +WG NGY+KMAKD
Sbjct: 297  KNSWGRDWGMNGYIKMAKD 315



 Score = 29.3 bits (64), Expect(2) = e-124
 Identities = 11/18 (61%), Positives = 15/18 (83%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            + RNN+CGI++ ASYP V
Sbjct: 314  KDRNNNCGIASDASYPVV 331


>ref|NP_954599.2| hypothetical protein LOC218275 [Mus musculus].
          Length = 330

 Score =  426 bits (1094), Expect(2) = e-121
 Identities = 201/318 (63%), Positives = 241/318 (75%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M P   L  LCLG+ SAAP  D +LDA W +WK  H + Y MNEE  +RAVWE NMKMI 
Sbjct: 1    MTPVFLLATLCLGVVSAAPAHDPSLDAVWEEWKTKHRKTYNMNEEAQKRAVWENNMKMIG 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
            LHN++Y +GKHGF++ MNAFGD+TN EFR++M GFQ+  HK+  +F E L+ +VPKSVDW
Sbjct: 61   LHNEDYLKGKHGFNLEMNAFGDLTNTEFRELMTGFQSMGHKEMTIFQEPLLGDVPKSVDW 120

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
            R+ GYVT VK+QG CGSCWAFSA G+LEGQ+FRKTGKLV LSEQNL+DCS   GN GCNG
Sbjct: 121  RDHGYVTPVKDQGHCGSCWAFSAVGSLEGQIFRKTGKLVPLSEQNLMDCSWSYGNVGCNG 180

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV 816
            GLM+ AFQYVK+N GLDT ESY Y   +   C Y P+ SA N TGFV +P  E ALM AV
Sbjct: 181  GLMELAFQYVKENRGLDTRESYAYEAWD-GPCRYDPKYSAVNITGFVKVPLSEDALMNAV 239

Query: 817  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 996
            A+VGP+SV ID  H SF+FY+ G YY+PDCSS +LDH VLVVGYG E   S+  K+W+VK
Sbjct: 240  ASVGPVSVGIDTHHHSFRFYRGGTYYEPDCSSTNLDHAVLVVGYGEE---SDGRKYWLVK 296

Query: 997  NSWGPEWGWNGYVKMAKD 1050
            NSWG +WG +GY+KMAKD
Sbjct: 297  NSWGEDWGMDGYIKMAKD 314



 Score = 28.5 bits (62), Expect(2) = e-121
 Identities = 11/18 (61%), Positives = 15/18 (83%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            + R+N+CGI+T A YPTV
Sbjct: 313  KDRDNNCGIATYAIYPTV 330


>ref|NP_835199.1| testin-2 precursor [Mus musculus].
          Length = 333

 Score =  420 bits (1079), Expect(2) = e-120
 Identities = 202/314 (64%), Positives = 232/314 (73%)
 Frame = +1

Query: 109  LFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIELHNQ 288
            LFL  LCL I S AP LD +LD  W +W+  HG+ Y +NEE  RRAVWEKN KMIELHN 
Sbjct: 5    LFLAILCLEIDSTAPTLDPSLDVQWNEWRTKHGKAYNVNEERLRRAVWEKNFKMIELHNW 64

Query: 289  EYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDWREKG 468
            EY +GKH F+M MNAFGD+TN EF ++M GF+ QK K+  VF +   L VPK VDWR  G
Sbjct: 65   EYLEGKHDFTMTMNAFGDLTNTEFVKMMTGFRRQKIKRMHVFQDHQFLYVPKYVDWRMLG 124

Query: 469  YVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMD 648
            YVT VKNQG C S WAFSATG+LEGQMF+KTG+LV LSEQNL+DC        C+GG M 
Sbjct: 125  YVTPVKNQGYCASSWAFSATGSLEGQMFKKTGRLVPLSEQNLLDCMGSNVTHDCSGGFMQ 184

Query: 649  NAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAVATVG 828
            NAFQYVKDNGGL TEESYPY+G     C Y  E SAAN   FV IP RE+ALMKAVA VG
Sbjct: 185  NAFQYVKDNGGLATEESYPYIG-PGRKCRYHAENSAANVRDFVQIPGREEALMKAVAKVG 243

Query: 829  PISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWG 1008
            PISVA+DA H SFQFY SGIYY+P C    L+H VLVVGYGFEG +S+ + +W+VKNSWG
Sbjct: 244  PISVAVDASHDSFQFYDSGIYYEPQCKRVHLNHAVLVVGYGFEGEESDGNSYWLVKNSWG 303

Query: 1009 PEWGWNGYVKMAKD 1050
             EWG  GY+K+AKD
Sbjct: 304  EEWGMKGYIKIAKD 317



 Score = 30.0 bits (66), Expect(2) = e-120
 Identities = 11/15 (73%), Positives = 13/15 (86%)
 Frame = +3

Query: 1056 NNHCGISTAASYPTV 1100
            NNHCGI+T A+YP V
Sbjct: 319  NNHCGIATLATYPIV 333


>ref|NP_071721.2| cathepsin M precursor [Mus musculus].
          Length = 333

 Score =  380 bits (977), Expect(2) = e-107
 Identities = 181/318 (56%), Positives = 231/318 (72%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M  ++FL  LCLG+A  +P  D  LD +W KWK  +G+ Y + EEG +RAVWE NMK I+
Sbjct: 1    MTSAIFLAMLCLGMALPSPAPDPILDVEWQKWKIKYGKAYSLEEEGQKRAVWEDNMKKIK 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
            LHN E   GKHGF+M MNAFGDMT EEFR+VM        KKGK   + L + +PK ++W
Sbjct: 61   LHNGENGLGKHGFTMEMNAFGDMTLEEFRKVMIEIPVPTVKKGKSVQKRLSVNLPKFINW 120

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
            +++GYVT V+ QG+C SCWAFS TGA+EGQMFRKTG+L+ LS QNLVDCSRPQGN GC  
Sbjct: 121  KKRGYVTPVQTQGRCNSCWAFSVTGAIEGQMFRKTGQLIPLSVQNLVDCSRPQGNWGCYL 180

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV 816
            G    A  YV +NGGL++E +YPY  ++  SC Y PE S AN TGF  +P+ E ALM AV
Sbjct: 181  GNTYLALHYVMENGGLESEATYPYEEKD-GSCRYSPENSTANITGFEFVPKNEDALMNAV 239

Query: 817  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 996
            A++GPISVAIDA H+SF FYK GIYY+P+CSS  + H +L+VGYGF G +S+  K+W+VK
Sbjct: 240  ASIGPISVAIDARHASFLFYKRGIYYEPNCSSSVVTHSMLLVGYGFTGRESDGRKYWLVK 299

Query: 997  NSWGPEWGWNGYVKMAKD 1050
            NS G +WG  GY+K+++D
Sbjct: 300  NSMGTQWGNKGYMKISRD 317



 Score = 28.5 bits (62), Expect(2) = e-107
 Identities = 11/18 (61%), Positives = 13/18 (72%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            R + NHCGI+T A YP V
Sbjct: 316  RDKGNHCGIATYALYPRV 333


>ref|NP_067420.1| cathepsin 6 [Mus musculus].
          Length = 334

 Score =  372 bits (955), Expect(2) = e-105
 Identities = 173/319 (54%), Positives = 228/319 (71%), Gaps = 1/319 (0%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M P+LFL  LCLG+ S A  LD NL+A+W+ WK  + + Y M EEG RRA+WE+NM+MI+
Sbjct: 1    MSPTLFLAILCLGVGSGALALDPNLNAEWHDWKKQYEKSYTMEEEGLRRAIWEENMRMIK 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEV-PKSVD 453
            LHN E S GK+ F++ MN FGD+T EE R++MN F    HKK K+  +  V +V PK VD
Sbjct: 61   LHNWENSLGKNNFTLKMNEFGDLTPEELRKMMNNFPIWSHKKRKIIRKRAVGDVLPKFVD 120

Query: 454  WREKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCN 633
            WR+KGYVT V+ Q  C SCWAF+  GA+EGQMF+KTGKL  LS QNLVDC++ QGN GC 
Sbjct: 121  WRKKGYVTRVRRQKFCNSCWAFAVNGAIEGQMFKKTGKLTPLSVQNLVDCTKTQGNDGCQ 180

Query: 634  GGLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKA 813
             G    A++YV +NGGL+ E +YPY G+E   C Y P+ S A  TGFV +P+ E  LM+A
Sbjct: 181  WGDPYIAYEYVLNNGGLEAEATYPYEGKE-GPCRYNPKNSKAEITGFVSLPESEDILMEA 239

Query: 814  VATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIV 993
            VAT+GPIS A+DA  + F FY  GIY+ P+CS+  ++H VLVVGYG EG +++ +K+W++
Sbjct: 240  VATIGPISAAVDASFNRFSFYDGGIYHQPNCSNNTVNHAVLVVGYGTEGNETDGNKYWLI 299

Query: 994  KNSWGPEWGWNGYVKMAKD 1050
            KNSWG  WG  GY+K+ +D
Sbjct: 300  KNSWGRRWGIGGYMKIIRD 318



 Score = 30.8 bits (68), Expect(2) = e-105
 Identities = 12/18 (66%), Positives = 14/18 (77%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            R +NNHCGI+T A YP V
Sbjct: 317  RDQNNHCGIATYAHYPIV 334


>ref|XP_922074.1| PREDICTED: cathepsin M-like [Mus musculus].
          Length = 333

 Score =  379 bits (973), Expect = e-105
 Identities = 182/318 (57%), Positives = 232/318 (72%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M P++FL  L L +AS++P  D  LDA+W KWK  HG+ Y + EE  +RAVWE+NMK I+
Sbjct: 1    MTPAVFLAILWLVMASSSPSPDPILDAEWQKWKIKHGKPYSLEEEEQKRAVWEENMKKIK 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
            LHN E   GKHGF+M MNAFGDMT EEFR+VM        KKGK   + L + +PK ++W
Sbjct: 61   LHNGENGLGKHGFTMEMNAFGDMTLEEFRKVMIEIPVPTVKKGKSVQKHLSVNLPKFINW 120

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
            +++GYVT V+ QG+C SCWA S TGA+EGQMF+KTG+L+ LS QNLVDCSRPQGN+GC  
Sbjct: 121  KKRGYVTPVRTQGRCNSCWAISVTGAIEGQMFQKTGQLIPLSVQNLVDCSRPQGNRGCYV 180

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV 816
            G    A +YV +NGGL++E +YPY  +E  SC Y PE S A+ TGF  +P+ E ALM AV
Sbjct: 181  GNTYRALKYVVENGGLESEATYPYEEKE-GSCRYNPENSTASITGFDFVPENEDALMNAV 239

Query: 817  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 996
            AT+GPISVAIDA H SF FYK GIY++P+CSS  + H +L+VGYGF G +S   K+WIVK
Sbjct: 240  ATIGPISVAIDARHESFLFYKRGIYHEPNCSSSVVTHAMLLVGYGFVGNESEGRKYWIVK 299

Query: 997  NSWGPEWGWNGYVKMAKD 1050
            NS G +WG  GY+K+A+D
Sbjct: 300  NSMGTKWGSKGYMKIARD 317


>ref|NP_062414.3| cathepsin 8 [Mus musculus].
          Length = 333

 Score =  365 bits (938), Expect(2) = e-103
 Identities = 172/317 (54%), Positives = 222/317 (70%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M P++ L  LCLG+A      D +LD++W +WK    + Y M EEG +RAVWE+NMK+++
Sbjct: 1    MGPAVLLAILCLGVAEVTQSSDPSLDSEWQEWKRKFNKNYSMEEEGQKRAVWEENMKLVK 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
             HN EY QGK  F+M +NAFGDMT EE+R+++        +K K  H+ +   +PK VDW
Sbjct: 61   QHNIEYDQGKKNFTMDVNAFGDMTGEEYRKMLTDIPVPNFRKKKSIHQPIAGYLPKFVDW 120

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
            R++G VT VKNQG C SCWAFSA GA+EGQMFRKTGKLV LS QNLVDCSR +GN GC  
Sbjct: 121  RKRGCVTPVKNQGTCNSCWAFSAAGAIEGQMFRKTGKLVPLSTQNLVDCSRLEGNFGCFK 180

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV 816
            G    A +YV  N GL+ E +YPY G +   C Y PE SAA  T F  +   EK LM+AV
Sbjct: 181  GSTFLALKYVWKNRGLEAESTYPYKGTD-GHCRYHPERSAARITSFSFVSNSEKDLMRAV 239

Query: 817  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 996
            AT+GPISV IDA H SF+ Y+ GIYY+P CSS  ++H VLVVGYG+EG +S+ +K+W++K
Sbjct: 240  ATIGPISVGIDARHKSFRLYREGIYYEPKCSSNIINHSVLVVGYGYEGKESDGNKYWLIK 299

Query: 997  NSWGPEWGWNGYVKMAK 1047
            NS G +WG NGY+K+A+
Sbjct: 300  NSHGEQWGMNGYMKLAR 316



 Score = 30.0 bits (66), Expect(2) = e-103
 Identities = 12/18 (66%), Positives = 14/18 (77%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            R RNNHCGI++ A YP V
Sbjct: 316  RGRNNHCGIASYAVYPRV 333


>ref|NP_064680.1| cathepsin R precursor [Mus musculus].
          Length = 334

 Score =  365 bits (937), Expect = e-101
 Identities = 171/319 (53%), Positives = 224/319 (70%), Gaps = 1/319 (0%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M   +F+  L LG+AS  P LD +LDA+W  WK  + + Y + EE  +R VWE+ +KMI+
Sbjct: 1    MAAVVFIAFLYLGVASGVPVLDSSLDAEWQDWKIKYNKSYSLKEEKLKRVVWEEKLKMIK 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGK-VFHESLVLEVPKSVD 453
            LHN+E S GK+GF+M MN FGD T+EEFR++M       H++GK +        +PK VD
Sbjct: 61   LHNRENSLGKNGFTMKMNEFGDQTDEEFRKMMIEISVWTHREGKSIMKREAGSILPKFVD 120

Query: 454  WREKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCN 633
            WR+KGYVT V+ QG C +CWAF+ TGA+E Q   +TGKL  LS QNLVDCS+PQGN GC 
Sbjct: 121  WRKKGYVTPVRRQGDCDACWAFAVTGAIEAQAIWQTGKLTPLSVQNLVDCSKPQGNNGCL 180

Query: 634  GGLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKA 813
            GG   NAFQYV  NGGL++E +YPY G++   C Y P+ S A  TGFV +PQ E  LM A
Sbjct: 181  GGDTYNAFQYVLHNGGLESEATYPYEGKD-GPCRYNPKNSKAEITGFVSLPQSEDILMAA 239

Query: 814  VATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIV 993
            VAT+GPI+  IDA H SF+ YK GIY++P+CSS  + HGVLVVGYGF+G +++ + +W++
Sbjct: 240  VATIGPITAGIDASHESFKNYKGGIYHEPNCSSDTVTHGVLVVGYGFKGIETDGNHYWLI 299

Query: 994  KNSWGPEWGWNGYVKMAKD 1050
            KNSWG  WG  GY+K+AKD
Sbjct: 300  KNSWGKRWGIRGYMKLAKD 318


>ref|NP_036137.1| cathepsin J [Mus musculus].
          Length = 333

 Score =  345 bits (886), Expect(2) = 2e-97
 Identities = 163/318 (51%), Positives = 217/318 (68%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M P++ L  LC G+AS A   D  LDA+W  WK  + + Y   EE  RRAVWE+NM+MI+
Sbjct: 1    MTPTVLLLILCFGVASGAQAHDPKLDAEWKDWKTKYAKSYSP-EEALRRAVWEENMRMIK 59

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
            LHN+E S GK+ F+M MN FGD T+EEFR+ ++                + + +P   DW
Sbjct: 60   LHNKENSLGKNNFTMKMNKFGDQTSEEFRKSIDNIPIPAAMTDPHAQNHVSIGLPDYKDW 119

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
            RE+GYVT V+NQG+CGSCWAF+A GA+EGQMF KTG L  LS QNL+DCS+  GN+GC  
Sbjct: 120  REEGYVTPVRNQGKCGSCWAFAAAGAIEGQMFWKTGNLTPLSVQNLLDCSKTVGNKGCQS 179

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV 816
            G    AF+YV  N GL+ E +YPY G++   C Y+ E ++AN T +V++P  E  L  AV
Sbjct: 180  GTAHQAFEYVLKNKGLEAEATYPYEGKD-GPCRYRSENASANITDYVNLPPNELYLWVAV 238

Query: 817  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 996
            A++GP+S AIDA H SF+FY  GIYY+P+CSS  ++H VLVVGYG EG   + + +W++K
Sbjct: 239  ASIGPVSAAIDASHDSFRFYNGGIYYEPNCSSYFVNHAVLVVGYGSEGDVKDGNNYWLIK 298

Query: 997  NSWGPEWGWNGYVKMAKD 1050
            NSWG EWG NGY+++AKD
Sbjct: 299  NSWGEEWGMNGYMQIAKD 316



 Score = 30.0 bits (66), Expect(2) = 2e-97
 Identities = 10/18 (55%), Positives = 14/18 (77%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            +  NNHCGI++ ASYP +
Sbjct: 315  KDHNNHCGIASLASYPNI 332


  Database: RefSeq49_MP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 15,617,559
  Number of sequences in database:  30,036
  
Lambda     K      H
   0.317    0.134    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 30036
Number of Hits to DB: 40,225,025
Number of extensions: 1117633
Number of successful extensions: 3240
Number of sequences better than 1.0e-05: 33
Number of HSP's gapped: 3163
Number of HSP's successfully gapped: 42
Length of query: 376
Length of database: 15,617,559
Length adjustment: 103
Effective length of query: 273
Effective length of database: 12,523,851
Effective search space: 3419011323
Effective search space used: 3419011323
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-008115
         (1128 letters)

Database: RefSeq49_HP.fasta 
           32,964 sequences; 18,297,164 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_001188504.1| cathepsin L2 preproprotein [Homo sapiens].        543   e-158
Alignment   gi|NP_001324.2| cathepsin L2 preproprotein [Homo sapiens].           543   e-158
Alignment   gi|NP_666023.1| cathepsin L1 preproprotein [Homo sapiens].           538   e-156
Alignment   gi|NP_001903.1| cathepsin L1 preproprotein [Homo sapiens].           538   e-156
Alignment   gi|NP_000387.1| cathepsin K preproprotein [Homo sapiens].            313   3e-86
Alignment   gi|NP_004070.3| cathepsin S isoform 1 preproprotein [Homo sapie...   303   1e-82
Alignment   gi|NP_001186668.1| cathepsin S isoform 2 preproprotein [Homo sa...   251   7e-67
Alignment   gi|NP_004381.2| pro-cathepsin H preproprotein [Homo sapiens].        205   7e-53
Alignment   gi|NP_003784.2| cathepsin F precursor [Homo sapiens].                189   4e-48
Alignment   gi|NP_001325.1| cathepsin O preproprotein [Homo sapiens].            129   4e-30

>ref|NP_001188504.1| cathepsin L2 preproprotein [Homo sapiens].
          Length = 334

 Score =  543 bits (1399), Expect(2) = e-158
 Identities = 259/319 (81%), Positives = 282/319 (88%), Gaps = 1/319 (0%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M  SL L A CLGIASA PK DQNLD  WY+WKATH RLYG NEEGWRRAVWEKNMKMIE
Sbjct: 1    MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
            LHN EYSQGKHGF+MAMNAFGDMTNEEFRQ+M  F+NQK +KGKVF E L L++PKSVDW
Sbjct: 61   LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW 120

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
            R+KGYVT VKNQ QCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
Sbjct: 121  RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGF-VDIPQREKALMKA 813
            G M  AFQYVK+NGGLD+EESYPY+  +   C Y+PE S ANDTGF V  P +EKALMKA
Sbjct: 181  GFMARAFQYVKENGGLDSEESYPYVAVD-EICKYRPENSVANDTGFTVVAPGKEKALMKA 239

Query: 814  VATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIV 993
            VATVGPISVA+DAGHSSFQFYKSGIY++PDCSSK+LDHGVLVVGYGFEG +SN+SK+W+V
Sbjct: 240  VATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLV 299

Query: 994  KNSWGPEWGWNGYVKMAKD 1050
            KNSWGPEWG NGYVK+AKD
Sbjct: 300  KNSWGPEWGSNGYVKIAKD 318



 Score = 34.7 bits (78), Expect(2) = e-158
 Identities = 13/18 (72%), Positives = 16/18 (88%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            + +NNHCGI+TAASYP V
Sbjct: 317  KDKNNHCGIATAASYPNV 334


>ref|NP_001324.2| cathepsin L2 preproprotein [Homo sapiens].
          Length = 334

 Score =  543 bits (1399), Expect(2) = e-158
 Identities = 259/319 (81%), Positives = 282/319 (88%), Gaps = 1/319 (0%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M  SL L A CLGIASA PK DQNLD  WY+WKATH RLYG NEEGWRRAVWEKNMKMIE
Sbjct: 1    MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
            LHN EYSQGKHGF+MAMNAFGDMTNEEFRQ+M  F+NQK +KGKVF E L L++PKSVDW
Sbjct: 61   LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW 120

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
            R+KGYVT VKNQ QCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
Sbjct: 121  RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGF-VDIPQREKALMKA 813
            G M  AFQYVK+NGGLD+EESYPY+  +   C Y+PE S ANDTGF V  P +EKALMKA
Sbjct: 181  GFMARAFQYVKENGGLDSEESYPYVAVD-EICKYRPENSVANDTGFTVVAPGKEKALMKA 239

Query: 814  VATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIV 993
            VATVGPISVA+DAGHSSFQFYKSGIY++PDCSSK+LDHGVLVVGYGFEG +SN+SK+W+V
Sbjct: 240  VATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLV 299

Query: 994  KNSWGPEWGWNGYVKMAKD 1050
            KNSWGPEWG NGYVK+AKD
Sbjct: 300  KNSWGPEWGSNGYVKIAKD 318



 Score = 34.7 bits (78), Expect(2) = e-158
 Identities = 13/18 (72%), Positives = 16/18 (88%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            + +NNHCGI+TAASYP V
Sbjct: 317  KDKNNHCGIATAASYPNV 334


>ref|NP_666023.1| cathepsin L1 preproprotein [Homo sapiens].
          Length = 333

 Score =  538 bits (1387), Expect(2) = e-156
 Identities = 251/318 (78%), Positives = 278/318 (87%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M P+L L A CLGIASA    D +L+A W KWKA H RLYGMNEEGWRRAVWEKNMKMIE
Sbjct: 1    MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
            LHNQEY +GKH F+MAMNAFGDMT+EEFRQVMNGFQN+K +KGKVF E L  E P+SVDW
Sbjct: 61   LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
            REKGYVT VKNQGQCGSCWAFSATGALEGQMFRKTG+L+SLSEQNLVDCS PQGN+GCNG
Sbjct: 121  REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV 816
            GLMD AFQYV+DNGGLD+EESYPY   E  SC Y P+ S ANDTGFVDIP++EKALMKAV
Sbjct: 181  GLMDYAFQYVQDNGGLDSEESYPYEATE-ESCKYNPKYSVANDTGFVDIPKQEKALMKAV 239

Query: 817  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 996
            ATVGPISVAIDAGH SF FYK GIY++PDCSS+D+DHGVLVVGYGFE T+S+++K+W+VK
Sbjct: 240  ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK 299

Query: 997  NSWGPEWGWNGYVKMAKD 1050
            NSWG EWG  GYVKMAKD
Sbjct: 300  NSWGEEWGMGGYVKMAKD 317



 Score = 33.9 bits (76), Expect(2) = e-156
 Identities = 13/18 (72%), Positives = 16/18 (88%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            + R NHCGI++AASYPTV
Sbjct: 316  KDRRNHCGIASAASYPTV 333


>ref|NP_001903.1| cathepsin L1 preproprotein [Homo sapiens].
          Length = 333

 Score =  538 bits (1387), Expect(2) = e-156
 Identities = 251/318 (78%), Positives = 278/318 (87%)
 Frame = +1

Query: 97   MKPSLFLTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIE 276
            M P+L L A CLGIASA    D +L+A W KWKA H RLYGMNEEGWRRAVWEKNMKMIE
Sbjct: 1    MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60

Query: 277  LHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDW 456
            LHNQEY +GKH F+MAMNAFGDMT+EEFRQVMNGFQN+K +KGKVF E L  E P+SVDW
Sbjct: 61   LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120

Query: 457  REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 636
            REKGYVT VKNQGQCGSCWAFSATGALEGQMFRKTG+L+SLSEQNLVDCS PQGN+GCNG
Sbjct: 121  REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180

Query: 637  GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAV 816
            GLMD AFQYV+DNGGLD+EESYPY   E  SC Y P+ S ANDTGFVDIP++EKALMKAV
Sbjct: 181  GLMDYAFQYVQDNGGLDSEESYPYEATE-ESCKYNPKYSVANDTGFVDIPKQEKALMKAV 239

Query: 817  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 996
            ATVGPISVAIDAGH SF FYK GIY++PDCSS+D+DHGVLVVGYGFE T+S+++K+W+VK
Sbjct: 240  ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK 299

Query: 997  NSWGPEWGWNGYVKMAKD 1050
            NSWG EWG  GYVKMAKD
Sbjct: 300  NSWGEEWGMGGYVKMAKD 317



 Score = 33.9 bits (76), Expect(2) = e-156
 Identities = 13/18 (72%), Positives = 16/18 (88%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYPTV 1100
            + R NHCGI++AASYPTV
Sbjct: 316  KDRRNHCGIASAASYPTV 333


>ref|NP_000387.1| cathepsin K preproprotein [Homo sapiens].
          Length = 329

 Score =  313 bits (803), Expect(2) = 3e-86
 Identities = 162/317 (51%), Positives = 207/317 (65%), Gaps = 5/317 (1%)
 Frame = +1

Query: 115  LTALCLGIASAAPKLDQNLDADWYKWKATHGRLYGMN-EEGWRRAVWEKNMKMIELHNQE 291
            L  L L + S A   ++ LD  W  WK TH + Y    +E  RR +WEKN+K I +HN E
Sbjct: 4    LKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLE 63

Query: 292  YSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQ---NQKHKKGKVFHESLVLEVPKSVDWRE 462
             S G H + +AMN  GDMT+EE  Q M G +   +       ++        P SVD+R+
Sbjct: 64   ASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRK 123

Query: 463  KGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGL 642
            KGYVT VKNQGQCGSCWAFS+ GALEGQ+ +KTGKL++LS QNLVDC     N GC GG 
Sbjct: 124  KGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC--VSENDGCGGGY 181

Query: 643  MDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQ-REKALMKAVA 819
            M NAFQYV+ N G+D+E++YPY+G+E  SC Y P   AA   G+ +IP+  EKAL +AVA
Sbjct: 182  MTNAFQYVQKNRGIDSEDAYPYVGQE-ESCMYNPTGKAAKCRGYREIPEGNEKALKRAVA 240

Query: 820  TVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKN 999
             VGP+SVAIDA  +SFQFY  G+YYD  C+S +L+H VL VGYG +      +K WI+KN
Sbjct: 241  RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ----KGNKHWIIKN 296

Query: 1000 SWGPEWGWNGYVKMAKD 1050
            SWG  WG  GY+ MA++
Sbjct: 297  SWGENWGNKGYILMARN 313



 Score = 24.6 bits (52), Expect(2) = 3e-86
 Identities = 9/16 (56%), Positives = 12/16 (75%)
 Frame = +3

Query: 1047 RPRNNHCGISTAASYP 1094
            R +NN CGI+  AS+P
Sbjct: 312  RNKNNACGIANLASFP 327


>ref|NP_004070.3| cathepsin S isoform 1 preproprotein [Homo sapiens].
          Length = 331

 Score =  303 bits (777), Expect = 1e-82
 Identities = 160/334 (47%), Positives = 212/334 (63%), Gaps = 8/334 (2%)
 Frame = +1

Query: 115  LTALCLGIASAAPKL--DQNLDADWYKWKATHGRLYG-MNEEGWRRAVWEKNMKMIELHN 285
            L  + L  +SA  +L  D  LD  W+ WK T+G+ Y   NEE  RR +WEKN+K + LHN
Sbjct: 4    LVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHN 63

Query: 286  QEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEV-PKSVDWRE 462
             E+S G H + + MN  GDMT+EE   +M+  +     +  + ++S    + P SVDWRE
Sbjct: 64   LEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWRE 123

Query: 463  KGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ-GNQGCNGG 639
            KG VT VK QG CG+CWAFSA GALE Q+  KTGKLVSLS QNLVDCS  + GN+GCNGG
Sbjct: 124  KGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGG 183

Query: 640  LMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQ-REKALMKAV 816
             M  AFQY+ DN G+D++ SYPY   +   C Y  +  AA  + + ++P  RE  L +AV
Sbjct: 184  FMTTAFQYIIDNKGIDSDASYPYKAMD-QKCQYDSKYRAATCSKYTELPYGREDVLKEAV 242

Query: 817  ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 996
            A  GP+SV +DA H SF  Y+SG+YY+P C +++++HGVLVVGYG    D N  ++W+VK
Sbjct: 243  ANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEYWLVK 297

Query: 997  NSWGPEWGWNGYVKMA--KDPETTTVEFPQQPAI 1092
            NSWG  +G  GY++MA  K        FP  P I
Sbjct: 298  NSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331


>ref|NP_001186668.1| cathepsin S isoform 2 preproprotein [Homo sapiens].
          Length = 281

 Score =  251 bits (642), Expect = 7e-67
 Identities = 141/333 (42%), Positives = 184/333 (55%), Gaps = 7/333 (2%)
 Frame = +1

Query: 115  LTALCLGIASAAPKL--DQNLDADWYKWKATHGRLYG-MNEEGWRRAVWEKNMKMIELHN 285
            L  + L  +SA  +L  D  LD  W+ WK T+G+ Y   NEE  RR +WEKN+K + LHN
Sbjct: 4    LVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHN 63

Query: 286  QEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDWREK 465
             E+S G H + + MN  GDM                                        
Sbjct: 64   LEHSMGMHSYDLGMNHLGDM---------------------------------------- 83

Query: 466  GYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ-GNQGCNGGL 642
                     G CG+CWAFSA GALE Q+  KTGKLVSLS QNLVDCS  + GN+GCNGG 
Sbjct: 84   ---------GSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGF 134

Query: 643  MDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQ-REKALMKAVA 819
            M  AFQY+ DN G+D++ SYPY   +   C Y  +  AA  + + ++P  RE  L +AVA
Sbjct: 135  MTTAFQYIIDNKGIDSDASYPYKAMD-QKCQYDSKYRAATCSKYTELPYGREDVLKEAVA 193

Query: 820  TVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKN 999
              GP+SV +DA H SF  Y+SG+YY+P C +++++HGVLVVGYG    D N  ++W+VKN
Sbjct: 194  NKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEYWLVKN 248

Query: 1000 SWGPEWGWNGYVKMA--KDPETTTVEFPQQPAI 1092
            SWG  +G  GY++MA  K        FP  P I
Sbjct: 249  SWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 281


>ref|NP_004381.2| pro-cathepsin H preproprotein [Homo sapiens].
          Length = 335

 Score =  205 bits (521), Expect = 7e-53
 Identities = 122/319 (38%), Positives = 168/319 (52%), Gaps = 13/319 (4%)
 Frame = +1

Query: 115  LTALCLG-------IASAAPKLDQNLDADWYK-WKATHGRLYGMNEEGWRRAVWEKNMKM 270
            L  LC G       +  AA     +L+   +K W + H + Y   E   R   +  N + 
Sbjct: 5    LPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRK 64

Query: 271  IELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSV 450
            I  HN     G H F MA+N F DM+  E +      + Q     K  +       P SV
Sbjct: 65   INAHNN----GNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV 120

Query: 451  DWREKG-YVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQG 627
            DWR+KG +V+ VKNQG CGSCW FS TGALE  +   TGK++SL+EQ LVDC++   N G
Sbjct: 121  DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG 180

Query: 628  CNGGLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKP--ECSAANDTGFVDIPQREKA 801
            C GGL   AF+Y+  N G+  E++YPY G++   C ++P        D   + I   E+A
Sbjct: 181  CQGGLPSQAFEYILYNKGIMGEDTYPYQGKD-GYCKFQPGKAIGFVKDVANITI-YDEEA 238

Query: 802  LMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDC--SSKDLDHGVLVVGYGFEGTDSNS 975
            +++AVA   P+S A +     F  Y++GIY    C  +   ++H VL VGYG    + N 
Sbjct: 239  MVEAVALYNPVSFAFEV-TQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYG----EKNG 293

Query: 976  SKFWIVKNSWGPEWGWNGY 1032
              +WIVKNSWGP+WG NGY
Sbjct: 294  IPYWIVKNSWGPQWGMNGY 312


>ref|NP_003784.2| cathepsin F precursor [Homo sapiens].
          Length = 484

 Score =  189 bits (480), Expect = 4e-48
 Identities = 115/283 (40%), Positives = 157/283 (55%), Gaps = 5/283 (1%)
 Frame = +1

Query: 199  THGRLYGMNEEG-WRRAVWEKNM-KMIELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVM 372
            T+ R Y   EE  WR +V+  NM +  ++   +    ++G    +  F D+T EEFR + 
Sbjct: 193  TYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYG----VTKFSDLTEEEFRTIY 248

Query: 373  NGFQNQKHKKGKVFHESLVLEV-PKSVDWREKGYVTAVKNQGQCGSCWAFSATGALEGQM 549
                 +K    K+     V ++ P   DWR KG VT VK+QG CGSCWAFS TG +EGQ 
Sbjct: 249  LNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQW 308

Query: 550  FRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYLGRETNS 729
            F   G L+SLSEQ L+DC +   ++ C GGL  NA+  +K+ GGL+TE+ Y Y G    S
Sbjct: 309  FLNQGTLLSLSEQELLDCDKM--DKACMGGLPSNAYSAIKNLGGLETEDDYSYQG-HMQS 365

Query: 730  CTYKPECSAANDTGFVDIPQREKALMKAVATVGPISVAIDAGHSSFQFYKSGIY--YDPD 903
            C +  E +       V++ Q E+ L   +A  GPISVAI+A     QFY+ GI     P 
Sbjct: 366  CNFSAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINA--FGMQFYRHGISRPLRPL 423

Query: 904  CSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGWNGY 1032
            CS   +DH VL+VGYG    + +   FW +KNSWG +WG  GY
Sbjct: 424  CSPWLIDHAVLLVGYG----NRSDVPFWAIKNSWGTDWGEKGY 462


>ref|NP_001325.1| cathepsin O preproprotein [Homo sapiens].
          Length = 321

 Score =  129 bits (325), Expect = 4e-30
 Identities = 88/249 (35%), Positives = 125/249 (50%), Gaps = 7/249 (2%)
 Frame = +1

Query: 325  MNAFGDMTNEEFRQVMNGFQNQKHKKGKV-FHESLV-LEVPKSVDWREKGYVTAVKNQGQ 498
            +N F  +  EEF+ +    +  K  +     H S+  + +P   DWR+K  VT V+NQ  
Sbjct: 69   INQFSYLFPEEFKAIYLRSKPSKFPRYSAEVHMSIPNVSLPLRFDWRDKQVVTQVRNQQM 128

Query: 499  CGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYV-KDN 675
            CG CWAFS  GA+E     K   L  LS Q ++DCS    N GCNGG   NA  ++ K  
Sbjct: 129  CGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDCS--YNNYGCNGGSTLNALNWLNKMQ 186

Query: 676  GGLDTEESYPYLGRETNSCTYKPECSAANDTGF--VDIPQREKALMKAVATVGPISVAID 849
              L  +  YP+  +      +    S  +  G+   D   +E  + KA+ T GP+ V +D
Sbjct: 187  VKLVKDSEYPFKAQNGLCHYFSGSHSGFSIKGYSAYDFSDQEDEMAKALLTFGPLVVIVD 246

Query: 850  AGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGWNG 1029
            A   S+Q Y  GI     CSS + +H VL+ G+   G    S+ +WIV+NSWG  WG +G
Sbjct: 247  A--VSWQDYLGGI-IQHHCSSGEANHAVLITGFDKTG----STPYWIVRNSWGSSWGVDG 299

Query: 1030 Y--VKMAKD 1050
            Y  VKM  +
Sbjct: 300  YAHVKMGSN 308


  Database: RefSeq49_HP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,297,164
  Number of sequences in database:  32,964
  
Lambda     K      H
   0.317    0.134    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 32964
Number of Hits to DB: 47,290,912
Number of extensions: 1325692
Number of successful extensions: 3713
Number of sequences better than 1.0e-05: 22
Number of HSP's gapped: 3640
Number of HSP's successfully gapped: 28
Length of query: 376
Length of database: 18,297,164
Length adjustment: 104
Effective length of query: 272
Effective length of database: 14,868,908
Effective search space: 4044342976
Effective search space used: 4044342976
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)

BLASTN 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-008115
         (1128 letters)

Database: Sscrofa_10.2.fasta 
           4582 sequences; 2,808,509,378 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Sscrofa_Chr10                                                         448   e-123

>Sscrofa_Chr10 
||          Length = 79102373

 Score =  448 bits (226), Expect = e-123
 Identities = 229/230 (99%)
 Strand = Plus / Plus

                                                                            
Query: 489      tcagggtcagtgtggttcttgttgggcttttagtgccaccggcgccctcgaaggacagat 548
                |||||||||||||||||||||||||||||||||||||||||||||||| |||||||||||
Sbjct: 76999957 tcagggtcagtgtggttcttgttgggcttttagtgccaccggcgcccttgaaggacagat 77000016

                                                                            
Query: 549      gttccggaaaaccggcaagcttgtttcactgagtgagcagaacctggtggactgttctcg 608
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 77000017 gttccggaaaaccggcaagcttgtttcactgagtgagcagaacctggtggactgttctcg 77000076

                                                                            
Query: 609      gcctcaaggcaatcagggctgcaatggtggcctaatggataatgccttccagtacgtgaa 668
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 77000077 gcctcaaggcaatcagggctgcaatggtggcctaatggataatgccttccagtacgtgaa 77000136

                                                                  
Query: 669      ggacaatggaggcctggacacagaggaatcctatccgtaccttggaaggg 718
                ||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 77000137 ggacaatggaggcctggacacagaggaatcctatccgtaccttggaaggg 77000186



 Score =  339 bits (171), Expect = 2e-90
 Identities = 213/227 (93%)
 Strand = Plus / Minus

                                                                            
Query: 489      tcagggtcagtgtggttcttgttgggcttttagtgccaccggcgccctcgaaggacagat 548
                ||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 31911743 tcagggtcactgtggttcttgttgggcttttagtgccaccggcgccctcgaaggacagat 31911684

                                                                            
Query: 549      gttccggaaaaccggcaagcttgtttcactgagtgagcagaacctggtggactgttctcg 608
                ||||||||||||| |||| ||| ||||||||||||||||||||||||||||||| ||| |
Sbjct: 31911683 gttccggaaaaccagcaaacttatttcactgagtgagcagaacctggtggactgctcttg 31911624

                                                                            
Query: 609      gcctcaaggcaatcagggctgcaatggtggcctaatggataatgccttccagtacgtgaa 668
                |||| | |||||| ||||||||||||||||||||||||||||||||||||||||| | ||
Sbjct: 31911623 gcctgagggcaatgagggctgcaatggtggcctaatggataatgccttccagtacattaa 31911564

                                                               
Query: 669      ggacaatggaggcctggacacagaggaatcctatccgtaccttggaa 715
                ||||||||||||||||||| |||||||||||||||| ||| ||||||
Sbjct: 31911563 ggacaatggaggcctggactcagaggaatcctatccatactttggaa 31911517



 Score =  333 bits (168), Expect = 1e-88
 Identities = 168/168 (100%)
 Strand = Plus / Plus

                                                                            
Query: 717      ggaaacaaacagctgtacctataagcccgagtgttctgctgccaacgacaccggcttcgt 776
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 77000879 ggaaacaaacagctgtacctataagcccgagtgttctgctgccaacgacaccggcttcgt 77000938

                                                                            
Query: 777      ggacatccctcagcgggagaaggcccttatgaaggcagtcgcaactgtggggcccatctc 836
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 77000939 ggacatccctcagcgggagaaggcccttatgaaggcagtcgcaactgtggggcccatctc 77000998

                                                                
Query: 837      tgttgctattgatgcgggccattcatctttccagttctataagtcagg 884
                ||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 77000999 tgttgctattgatgcgggccattcatctttccagttctataagtcagg 77001046



 Score =  295 bits (149), Expect = 3e-77
 Identities = 149/149 (100%)
 Strand = Plus / Plus

                                                                            
Query: 345      gaccaatgaagaattcaggcaggtgatgaatggctttcaaaaccagaagcacaagaaggg 404
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 76999715 gaccaatgaagaattcaggcaggtgatgaatggctttcaaaaccagaagcacaagaaggg 76999774

                                                                            
Query: 405      gaaagtgttccacgaatctctggttcttgaggtccccaaatcggtagattggagagaaaa 464
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 76999775 gaaagtgttccacgaatctctggttcttgaggtccccaaatcggtagattggagagaaaa 76999834

                                             
Query: 465      aggctatgtcactgccgtgaagaatcagg 493
                |||||||||||||||||||||||||||||
Sbjct: 76999835 aggctatgtcactgccgtgaagaatcagg 76999863



 Score =  276 bits (139), Expect = 2e-71
 Identities = 139/139 (100%)
 Strand = Plus / Plus

                                                                            
Query: 84       aggtttttgaaacatgaaaccttcactcttcctgaccgccctttgcttgggaatagcctc 143
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 76999070 aggtttttgaaacatgaaaccttcactcttcctgaccgccctttgcttgggaatagcctc 76999129

                                                                            
Query: 144      agctgctccaaaacttgatcaaaatttagatgcagactggtacaagtggaaggcaacaca 203
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 76999130 agctgctccaaaacttgatcaaaatttagatgcagactggtacaagtggaaggcaacaca 76999189

                                   
Query: 204      cgggagactctatggcatg 222
                |||||||||||||||||||
Sbjct: 76999190 cgggagactctatggcatg 76999208



 Score =  246 bits (124), Expect = 2e-62
 Identities = 124/124 (100%)
 Strand = Plus / Plus

                                                                            
Query: 222      gaatgaagaaggatggcggagagccgtatgggagaagaatatgaaaatgattgaactgca 281
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 76999489 gaatgaagaaggatggcggagagccgtatgggagaagaatatgaaaatgattgaactgca 76999548

                                                                            
Query: 282      caatcaggaatacagccaagggaaacatggcttcagcatggccatgaatgcctttggtga 341
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 76999549 caatcaggaatacagccaagggaaacatggcttcagcatggccatgaatgcctttggtga 76999608

                    
Query: 342      catg 345
                ||||
Sbjct: 76999609 catg 76999612



 Score =  240 bits (121), Expect = 1e-60
 Identities = 121/121 (100%)
 Strand = Plus / Plus

                                                                            
Query: 881      caggcatttattatgatccagactgcagcagcaaagacctggatcatggtgttttggtgg 940
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 77001763 caggcatttattatgatccagactgcagcagcaaagacctggatcatggtgttttggtgg 77001822

                                                                            
Query: 941      ttggctatggctttgaaggaactgattcaaatagcagtaaattttggattgtcaagaaca 1000
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 77001823 ttggctatggctttgaaggaactgattcaaatagcagtaaattttggattgtcaagaaca 77001882

                 
Query: 1001     g 1001
                |
Sbjct: 77001883 g 77001883



 Score =  226 bits (114), Expect = 2e-56
 Identities = 128/130 (98%), Gaps = 2/130 (1%)
 Strand = Plus / Plus

                                                                            
Query: 999      cagttggggtccagaatggggctggaacggctacgtaaaaatggccaaagacccagaaac 1058
                ||||||||||||||||||||||||||||||||||||||||||||||||||||| |||| |
Sbjct: 77003099 cagttggggtccagaatggggctggaacggctacgtaaaaatggccaaagacc-agaa-c 77003156

                                                                            
Query: 1059     aaccactgtggaatttccacagcagccagctatcccaccgtgtgagctgacggatggtga 1118
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 77003157 aaccactgtggaatttccacagcagccagctatcccaccgtgtgagctgacggatggtga 77003216

                          
Query: 1119     gaatagagga 1128
                ||||||||||
Sbjct: 77003217 gaatagagga 77003226



 Score =  165 bits (83), Expect = 7e-38
 Identities = 119/131 (90%)
 Strand = Plus / Minus

                                                                            
Query: 89       tttgaaacatgaaaccttcactcttcctgaccgccctttgcttgggaatagcctcagctg 148
                |||||| |||||| ||||||||| ||||| | ||| ||||||||||||||||||||||||
Sbjct: 31912935 tttgaagcatgaatccttcactcctcctggctgccttttgcttgggaatagcctcagctg 31912876

                                                                            
Query: 149      ctccaaaacttgatcaaaatttagatgcagactggtacaagtggaaggcaacacacggga 208
                |||||| || |||||| | ||||||||||||||||||||||||||||||||||||| |||
Sbjct: 31912875 ctccaagacatgatcacagtttagatgcagactggtacaagtggaaggcaacacacagga 31912816

                           
Query: 209      gactctatggc 219
                 ||||||||||
Sbjct: 31912815 aactctatggc 31912805



 Score =  165 bits (83), Expect = 7e-38
 Identities = 83/83 (100%)
 Strand = Plus / Plus

                                                                            
Query: 5        ggccagaacctcgagccaccgccaacttaggagagatacgtacgtccgtggagtgcgcct 64
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 76997823 ggccagaacctcgagccaccgccaacttaggagagatacgtacgtccgtggagtgcgcct 76997882

                                       
Query: 65       gcgtagcggtggaagccgcaggt 87
                |||||||||||||||||||||||
Sbjct: 76997883 gcgtagcggtggaagccgcaggt 76997905



 Score =  159 bits (80), Expect = 4e-36
 Identities = 113/124 (91%)
 Strand = Plus / Minus

                                                                            
Query: 222      gaatgaagaaggatggcggagagccgtatgggagaagaatatgaaaatgattgaactgca 281
                ||||||||||||| ||||||||||| ||||||||||||| ||||||||||||||||  ||
Sbjct: 31912505 gaatgaagaaggaaggcggagagccatatgggagaagaacatgaaaatgattgaacgaca 31912446

                                                                            
Query: 282      caatcaggaatacagccaagggaaacatggcttcagcatggccatgaatgcctttggtga 341
                ||||  |||| |||| |||||||||||| |||||| ||||||||||||||||||||||||
Sbjct: 31912445 caattgggaacacaggcaagggaaacatagcttcaccatggccatgaatgcctttggtga 31912386

                    
Query: 342      catg 345
                ||||
Sbjct: 31912385 catg 31912382



 Score = 99.6 bits (50), Expect = 3e-18
 Identities = 113/134 (84%)
 Strand = Plus / Minus

                                                                            
Query: 739      aagcccgagtgttctgctgccaacgacaccggcttcgtggacatccctcagcgggagaag 798
                |||||| || ||||||||||||||||||| || | |||||| || ||  ||| |||||| 
Sbjct: 31910738 aagccccagagttctgctgccaacgacactggttacgtggatattccaaagcaggagaaa 31910679

                                                                            
Query: 799      gcccttatgaaggcagtcgcaactgtggggcccatctctgttgctattgatgcgggccat 858
                || ||||||||||| || ||||||||||||||||||||||||| ||| |||||  |||||
Sbjct: 31910678 gcgcttatgaaggccgtggcaactgtggggcccatctctgttggtatagatgcaagccat 31910619

                              
Query: 859      tcatctttccagtt 872
                  ||| ||||||||
Sbjct: 31910618 gaatccttccagtt 31910605



 Score = 93.7 bits (47), Expect = 2e-16
 Identities = 65/71 (91%)
 Strand = Plus / Minus

                                                                            
Query: 345      gaccaatgaagaattcaggcaggtgatgaatggctttcaaaaccagaagcacaagaaggg 404
                ||||||||||||||||||| ||  ||||||||| ||||||||||||||||||||||||||
Sbjct: 31912281 gaccaatgaagaattcaggaagacgatgaatggttttcaaaaccagaagcacaagaaggg 31912222

                           
Query: 405      gaaagtgttcc 415
                 ||||| ||||
Sbjct: 31912221 aaaagtattcc 31912211



 Score = 79.8 bits (40), Expect = 3e-12
 Identities = 70/80 (87%)
 Strand = Plus / Minus

                                                                            
Query: 881      caggcatttattatgatccagactgcagcagcaaagacctggatcatggtgttttggtgg 940
                |||||||||||| ||| ||| | ||||||||| |||| ||||||||||| ||| ||||||
Sbjct: 31909183 caggcatttattttgaaccacagtgcagcagcgaagatctggatcatggcgttctggtgg 31909124

                                    
Query: 941      ttggctatggctttgaagga 960
                | ||||||||| ||||||||
Sbjct: 31909123 tcggctatggcgttgaagga 31909104


  Database: Sscrofa_10.2.fasta
    Posted date:  Nov 16, 2011 10:34 AM
  Number of letters in database: 2,808,509,378
  Number of sequences in database:  4582
  
Lambda     K      H
    1.37    0.711     1.31 

Gapped
Lambda     K      H
    1.37    0.711     1.31 


Matrix: blastn matrix:1 -3
Gap Penalties: Existence: 5, Extension: 2
Number of Sequences: 4582
Number of Hits to DB: 32,064,848
Number of extensions: 247
Number of successful extensions: 247
Number of sequences better than 1.0e-05: 1
Number of HSP's gapped: 246
Number of HSP's successfully gapped: 15
Length of query: 1128
Length of database: 2,808,509,378
Length adjustment: 21
Effective length of query: 1107
Effective length of database: 2,808,413,156
Effective search space: 3108913363692
Effective search space used: 3108913363692
X1: 11 (21.8 bits)
X2: 15 (29.7 bits)
X3: 50 (99.1 bits)
S1: 18 (36.2 bits)
S2: 30 (60.0 bits)