Animal-Genome cDNA 20110601C-008867

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-008867
         (1245 letters)

Database: RefSeq49_BP.fasta 
           33,088 sequences; 17,681,374 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_001029750.1| leucine-rich repeat-containing protein 59 [B...   477   e-134
Alignment   gi|NP_001094631.1| CCR4-NOT transcription complex subunit 6 [Bo...    72   8e-13
Alignment   gi|NP_001026924.2| leucine rich repeat containing 57 [Bos tauru...    70   3e-12
Alignment   gi|XP_001254059.1| PREDICTED: leucine rich repeat containing 57...    70   3e-12
Alignment   gi|XP_001254043.1| PREDICTED: leucine rich repeat containing 57...    70   3e-12
Alignment   gi|NP_001178452.1| CCR4-NOT transcription complex, subunit 6-li...    69   9e-12
Alignment   gi|NP_001068764.1| E3 ubiquitin-protein ligase LRSAM1 [Bos taur...    67   3e-11
Alignment   gi|NP_001178416.1| leucine-rich repeat and death domain-contain...    67   4e-11
Alignment   gi|XP_002699454.1| PREDICTED: leucine-rich repeats and death do...    67   4e-11
Alignment   gi|NP_001035691.1| ras suppressor protein 1 [Bos taurus].             65   1e-10

>ref|NP_001029750.1| leucine-rich repeat-containing protein 59 [Bos taurus].
          Length = 306

 Score =  477 bits (1227), Expect = e-134
 Identities = 247/304 (81%), Positives = 250/304 (82%)
 Frame = +1

Query: 220  MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCG 399
            MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAAL KAT+LDLSCNKLTTLPS+FCG
Sbjct: 1    MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALPKATVLDLSCNKLTTLPSDFCG 60

Query: 400  LTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            LTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL
Sbjct: 61   LTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 120

Query: 580  DPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEIDREAEKKWEAKQXXX 759
            DPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEIDREAEKKWEAKQ   
Sbjct: 121  DPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEIDREAEKKWEAKQRAK 180

Query: 760  XXXXXXXXXXXXXXXXXXXXXXYDALKAAKREQEKKPKKETNQAXXXXXXXXXXXXXXXX 939
                                  YDALKAAKREQEKKPKKETNQA                
Sbjct: 181  EAQERELRKREKAEEKERRRKEYDALKAAKREQEKKPKKETNQAPKSKSSSRPRKPPPRK 240

Query: 940  XXXXWAVLXXXXXXXXCVAGGLVACRVTELQQQPLCTSVNTIYDNAVRGLRSHDIVQWVL 1119
                WAVL        CVAGGLVACRVTELQQQPLCTSVNTIYDNAVRGLRSHDI+QWVL
Sbjct: 241  HTRSWAVLKLLLLLLLCVAGGLVACRVTELQQQPLCTSVNTIYDNAVRGLRSHDILQWVL 300

Query: 1120 QTDS 1131
            QTDS
Sbjct: 301  QTDS 304


>ref|NP_001094631.1| CCR4-NOT transcription complex subunit 6 [Bos taurus].
          Length = 557

 Score = 72.4 bits (176), Expect = 8e-13
 Identities = 41/86 (47%), Positives = 54/86 (62%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L +L+  T L LS N L+ +PS+   L +LV LDLS NK+R LPA+ G +V+L+ L L N
Sbjct: 47  LWSLTHLTALYLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNN 106

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPL 579
           N L  LP    +L  L+ L LK NPL
Sbjct: 107 NLLRVLPFELGKLFQLQTLGLKGNPL 132



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 29/71 (40%), Positives = 43/71 (60%)
 Frame = +1

Query: 367 KLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKS 546
           K+ +L S    LTHL  L LS N L ++P+D  +L NL +LDL +N++ +LP     + S
Sbjct: 39  KVRSLSSSLWSLTHLTALYLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVS 98

Query: 547 LKWLDLKDNPL 579
           L+ L L +N L
Sbjct: 99  LRELHLNNNLL 109



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 32/78 (41%), Positives = 45/78 (57%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L LS + L+ +P  ++A L     LDLS NK+ +LP+E   +  L +L L+ N LR LP 
Sbjct: 56  LYLSDNSLSRIP-SDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPF 114

Query: 457 DFGRLVNLQHLDLLNNRL 510
           + G+L  LQ L L  N L
Sbjct: 115 ELGKLFQLQTLGLKGNPL 132


>ref|NP_001026924.2| leucine rich repeat containing 57 [Bos taurus].
          Length = 239

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 40/108 (37%), Positives = 58/108 (53%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           +DLS + +  +P   +   +    L L+ NKLT LP E C L  L  L L+ N+LR+LP+
Sbjct: 43  IDLSNNKIENLPPMIIGKFTLLKSLSLNNNKLTALPDELCNLKKLETLSLNNNQLRELPS 102

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKV 600
            FG+L  L+ L L  N+L  LP     L+ L  +DL  N +  +L  V
Sbjct: 103 TFGQLSALKTLSLSGNQLRALPPQLCSLRHLDVVDLSKNQIRSILDTV 150



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 39/95 (41%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
 Frame = +1

Query: 298 LNEVPVKELAALSKATILDLSCNKLTTLPSEFCG-LTHLVKLDLSKNKLRQLPADFGRLV 474
           L E P +     S    +DLS NK+  LP    G  T L  L L+ NKL  LP +   L 
Sbjct: 26  LTEFPSELQKLTSNLRTIDLSNNKIENLPPMIIGKFTLLKSLSLNNNKLTALPDELCNLK 85

Query: 475 NLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            L+ L L NN+L  LP +F QL +LK L L  N L
Sbjct: 86  KLETLSLNNNQLRELPSTFGQLSALKTLSLSGNQL 120



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 36/102 (35%), Positives = 55/102 (53%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L E+P      LS    L LS N+L  LP + C L HL  +DLSKN++R +  
Sbjct: 90  LSLNNNQLRELP-STFGQLSALKTLSLSGNQLRALPPQLCSLRHLDVVDLSKNQIRSILD 148

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
             G L  ++ L+L  N++  + V  +    LK L L++N L+
Sbjct: 149 TVGELQVIE-LNLNQNQISQISVKISSCPRLKVLRLEENCLE 189


>ref|XP_001254059.1| PREDICTED: leucine rich repeat containing 57-like isoform 2 [Bos
           taurus].
          Length = 239

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 40/108 (37%), Positives = 58/108 (53%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           +DLS + +  +P   +   +    L L+ NKLT LP E C L  L  L L+ N+LR+LP+
Sbjct: 43  IDLSNNKIENLPPMIIGKFTLLKSLSLNNNKLTALPDELCNLKKLETLSLNNNQLRELPS 102

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKV 600
            FG+L  L+ L L  N+L  LP     L+ L  +DL  N +  +L  V
Sbjct: 103 TFGQLSALKTLSLSGNQLRALPPQLCSLRHLDVVDLSKNQIRSILDTV 150



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 39/95 (41%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
 Frame = +1

Query: 298 LNEVPVKELAALSKATILDLSCNKLTTLPSEFCG-LTHLVKLDLSKNKLRQLPADFGRLV 474
           L E P +     S    +DLS NK+  LP    G  T L  L L+ NKL  LP +   L 
Sbjct: 26  LTEFPSELQKLTSNLRTIDLSNNKIENLPPMIIGKFTLLKSLSLNNNKLTALPDELCNLK 85

Query: 475 NLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            L+ L L NN+L  LP +F QL +LK L L  N L
Sbjct: 86  KLETLSLNNNQLRELPSTFGQLSALKTLSLSGNQL 120



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 36/102 (35%), Positives = 55/102 (53%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L E+P      LS    L LS N+L  LP + C L HL  +DLSKN++R +  
Sbjct: 90  LSLNNNQLRELP-STFGQLSALKTLSLSGNQLRALPPQLCSLRHLDVVDLSKNQIRSILD 148

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
             G L  ++ L+L  N++  + V  +    LK L L++N L+
Sbjct: 149 TVGELQVIE-LNLNQNQISQISVKISSCPRLKVLRLEENCLE 189


>ref|XP_001254043.1| PREDICTED: leucine rich repeat containing 57-like isoform 1 [Bos
           taurus].
          Length = 239

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 40/108 (37%), Positives = 58/108 (53%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           +DLS + +  +P   +   +    L L+ NKLT LP E C L  L  L L+ N+LR+LP+
Sbjct: 43  IDLSNNKIENLPPMIIGKFTLLKSLSLNNNKLTALPDELCNLKKLETLSLNNNQLRELPS 102

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKV 600
            FG+L  L+ L L  N+L  LP     L+ L  +DL  N +  +L  V
Sbjct: 103 TFGQLSALKTLSLSGNQLRALPPQLCSLRHLDVVDLSKNQIRSILDTV 150



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 39/95 (41%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
 Frame = +1

Query: 298 LNEVPVKELAALSKATILDLSCNKLTTLPSEFCG-LTHLVKLDLSKNKLRQLPADFGRLV 474
           L E P +     S    +DLS NK+  LP    G  T L  L L+ NKL  LP +   L 
Sbjct: 26  LTEFPSELQKLTSNLRTIDLSNNKIENLPPMIIGKFTLLKSLSLNNNKLTALPDELCNLK 85

Query: 475 NLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            L+ L L NN+L  LP +F QL +LK L L  N L
Sbjct: 86  KLETLSLNNNQLRELPSTFGQLSALKTLSLSGNQL 120



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 36/102 (35%), Positives = 55/102 (53%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L E+P      LS    L LS N+L  LP + C L HL  +DLSKN++R +  
Sbjct: 90  LSLNNNQLRELP-STFGQLSALKTLSLSGNQLRALPPQLCSLRHLDVVDLSKNQIRSILD 148

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
             G L  ++ L+L  N++  + V  +    LK L L++N L+
Sbjct: 149 TVGELQVIE-LNLNQNQISQISVKISSCPRLKVLRLEENCLE 189


>ref|NP_001178452.1| CCR4-NOT transcription complex, subunit 6-like [Bos taurus].
          Length = 555

 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 40/86 (46%), Positives = 53/86 (61%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L +L+  T L L+ N L+ +P +   L +LV LDLS NKLR LPA+ G +V+L+ L L N
Sbjct: 52  LWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNN 111

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPL 579
           N L  LP    +L  L+ L LK NPL
Sbjct: 112 NLLRVLPYELGRLFQLQTLGLKGNPL 137



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 33/78 (42%), Positives = 45/78 (57%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L+ +P  ++A L     LDLS NKL +LP+E   +  L +L L+ N LR LP 
Sbjct: 61  LHLNDNYLSRIP-PDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNNNLLRVLPY 119

Query: 457 DFGRLVNLQHLDLLNNRL 510
           + GRL  LQ L L  N L
Sbjct: 120 ELGRLFQLQTLGLKGNPL 137



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 27/71 (38%), Positives = 42/71 (59%)
 Frame = +1

Query: 367 KLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKS 546
           ++ +L +    LTHL  L L+ N L ++P D  +L NL +LDL +N+L +LP     + S
Sbjct: 44  RVRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVS 103

Query: 547 LKWLDLKDNPL 579
           L+ L L +N L
Sbjct: 104 LRELLLNNNLL 114


>ref|NP_001068764.1| E3 ubiquitin-protein ligase LRSAM1 [Bos taurus].
          Length = 724

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 38/90 (42%), Positives = 56/90 (62%), Gaps = 2/90 (2%)
 Frame = +1

Query: 316 KELAALSKATI--LDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHL 489
           K  + LS ATI  LDL  N+LT LP +   LT L  L++ +N+L  LP   G L+ LQ L
Sbjct: 73  KSCSLLSLATIKVLDLHDNQLTALPDDIGQLTALQVLNMERNQLTYLPRSIGNLIQLQTL 132

Query: 490 DLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
           ++ +NRL  LP +  +L+SL+ LD+ +N +
Sbjct: 133 NVKDNRLKELPDTLGELRSLRTLDISENEI 162



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 31/96 (32%), Positives = 53/96 (55%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           LDL  + L  +P  ++  L+   +L++  N+LT LP     L  L  L++  N+L++LP 
Sbjct: 86  LDLHDNQLTALP-DDIGQLTALQVLNMERNQLTYLPRSIGNLIQLQTLNVKDNRLKELPD 144

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDL 564
             G L +L+ LD+  N +  LP   A +++L+ L L
Sbjct: 145 TLGELRSLRTLDISENEIQRLPRMLAHVRTLETLSL 180


>ref|NP_001178416.1| leucine-rich repeat and death domain-containing protein [Bos
           taurus].
          Length = 913

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 45/107 (42%), Positives = 62/107 (57%)
 Frame = +1

Query: 283 LSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADF 462
           LS + L+E+P   L AL   T L ++ N+L TLP     L+ L +LDLS N L  LP + 
Sbjct: 158 LSRNCLSELPAA-LGALPALTFLAVTHNRLRTLPPALGALSSLQRLDLSGNLLEALPPEI 216

Query: 463 GRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
           G L +L  L+L +NRL +LP S A L++L+   L  N L  V A +A
Sbjct: 217 GGLGSLAELNLASNRLQSLPSSLAGLRALRLFILHSNLLASVPASLA 263



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 51/126 (40%), Positives = 70/126 (55%), Gaps = 3/126 (2%)
 Frame = +1

Query: 238 KGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPS---EFCGLTH 408
           KGG  R+ L G  L  SL+ L       L++L++   LDLS N L TLP+   + CGL  
Sbjct: 101 KGGQRREAL-GACLRGSLATLPA----SLSSLARLAHLDLSFNSLETLPACVPQMCGLDA 155

Query: 409 LVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
           L+   LS+N L +LPA  G L  L  L + +NRL TLP +   L SL+ LDL  N L+ +
Sbjct: 156 LL---LSRNCLSELPAALGALPALTFLAVTHNRLRTLPPALGALSSLQRLDLSGNLLEAL 212

Query: 589 LAKVAG 606
             ++ G
Sbjct: 213 PPEIGG 218



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 39/89 (43%), Positives = 51/89 (57%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L ALS    LDLS N L  LP E  GL  L +L+L+ N+L+ LP+    L  L+   L +
Sbjct: 193 LGALSSLQRLDLSGNLLEALPPEIGGLGSLAELNLASNRLQSLPSSLAGLRALRLFILHS 252

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
           N L ++P S A+L  L  LDL+DN L  V
Sbjct: 253 NLLASVPASLARLPLLTRLDLRDNQLRDV 281



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 52/158 (32%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
 Frame = +1

Query: 139 PSVHERLLSLSPARRSPGAGTRSAGVTMTKAGSKGGNLRDKLDGNELDLSLSDLNEVP-- 312
           P +   +L     R + GA  R +  T+  + S    L        LDLS + L  +P  
Sbjct: 93  PRLRSLVLKGGQRREALGACLRGSLATLPASLSSLARLA------HLDLSFNSLETLPAC 146

Query: 313 VKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLD 492
           V ++  L     L LS N L+ LP+    L  L  L ++ N+LR LP   G L +LQ LD
Sbjct: 147 VPQMCGLDA---LLLSRNCLSELPAALGALPALTFLAVTHNRLRTLPPALGALSSLQRLD 203

Query: 493 LLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
           L  N L  LP     L SL  L+L  N L  + + +AG
Sbjct: 204 LSGNLLEALPPEIGGLGSLAELNLASNRLQSLPSSLAG 241



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 37/101 (36%), Positives = 52/101 (51%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           LDLS + L  +P  E+  L     L+L+ N+L +LPS   GL  L    L  N L  +PA
Sbjct: 202 LDLSGNLLEALP-PEIGGLGSLAELNLASNRLQSLPSSLAGLRALRLFILHSNLLASVPA 260

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
              RL  L  LDL +N+L  +P    +L    ++ L+ NPL
Sbjct: 261 SLARLPLLTRLDLRDNQLRDVP---PELLDAPFVRLQGNPL 298


>ref|XP_002699454.1| PREDICTED: leucine-rich repeats and death domain containing [Bos
           taurus].
          Length = 913

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 45/107 (42%), Positives = 62/107 (57%)
 Frame = +1

Query: 283 LSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADF 462
           LS + L+E+P   L AL   T L ++ N+L TLP     L+ L +LDLS N L  LP + 
Sbjct: 158 LSRNCLSELPAA-LGALPALTFLAVTHNRLRTLPPALGALSSLQRLDLSGNLLEALPPEI 216

Query: 463 GRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
           G L +L  L+L +NRL +LP S A L++L+   L  N L  V A +A
Sbjct: 217 GGLGSLAELNLASNRLQSLPSSLAGLRALRLFILHSNLLASVPASLA 263



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 51/126 (40%), Positives = 70/126 (55%), Gaps = 3/126 (2%)
 Frame = +1

Query: 238 KGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPS---EFCGLTH 408
           KGG  R+ L G  L  SL+ L       L++L++   LDLS N L TLP+   + CGL  
Sbjct: 101 KGGQRREAL-GACLRGSLATLPA----SLSSLARLAHLDLSFNSLETLPACVPQMCGLDA 155

Query: 409 LVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
           L+   LS+N L +LPA  G L  L  L + +NRL TLP +   L SL+ LDL  N L+ +
Sbjct: 156 LL---LSRNCLSELPAALGALPALTFLAVTHNRLRTLPPALGALSSLQRLDLSGNLLEAL 212

Query: 589 LAKVAG 606
             ++ G
Sbjct: 213 PPEIGG 218



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 39/89 (43%), Positives = 51/89 (57%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L ALS    LDLS N L  LP E  GL  L +L+L+ N+L+ LP+    L  L+   L +
Sbjct: 193 LGALSSLQRLDLSGNLLEALPPEIGGLGSLAELNLASNRLQSLPSSLAGLRALRLFILHS 252

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
           N L ++P S A+L  L  LDL+DN L  V
Sbjct: 253 NLLASVPASLARLPLLTRLDLRDNQLRDV 281



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 52/158 (32%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
 Frame = +1

Query: 139 PSVHERLLSLSPARRSPGAGTRSAGVTMTKAGSKGGNLRDKLDGNELDLSLSDLNEVP-- 312
           P +   +L     R + GA  R +  T+  + S    L        LDLS + L  +P  
Sbjct: 93  PRLRSLVLKGGQRREALGACLRGSLATLPASLSSLARLA------HLDLSFNSLETLPAC 146

Query: 313 VKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLD 492
           V ++  L     L LS N L+ LP+    L  L  L ++ N+LR LP   G L +LQ LD
Sbjct: 147 VPQMCGLDA---LLLSRNCLSELPAALGALPALTFLAVTHNRLRTLPPALGALSSLQRLD 203

Query: 493 LLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
           L  N L  LP     L SL  L+L  N L  + + +AG
Sbjct: 204 LSGNLLEALPPEIGGLGSLAELNLASNRLQSLPSSLAG 241



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 37/101 (36%), Positives = 52/101 (51%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           LDLS + L  +P  E+  L     L+L+ N+L +LPS   GL  L    L  N L  +PA
Sbjct: 202 LDLSGNLLEALP-PEIGGLGSLAELNLASNRLQSLPSSLAGLRALRLFILHSNLLASVPA 260

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
              RL  L  LDL +N+L  +P    +L    ++ L+ NPL
Sbjct: 261 SLARLPLLTRLDLRDNQLRDVP---PELLDAPFVRLQGNPL 298


>ref|NP_001035691.1| ras suppressor protein 1 [Bos taurus].
          Length = 277

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 42/114 (36%), Positives = 62/114 (54%), Gaps = 3/114 (2%)
 Frame = +1

Query: 250 LRDKLDGNELDLSLSDL---NEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKL 420
           + +  + N+ ++ +SD    N + +  L  LS  T L LS NKLTT+P     L +L  L
Sbjct: 9   VEESREKNQPEVDMSDRGISNMLDINGLFTLSHITQLVLSHNKLTTVPPNIAELKNLEVL 68

Query: 421 DLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
           +   N++ +LP     L  L+HL+L  NRL TLP  F  L +L+ LDL  N L+
Sbjct: 69  NFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLN 122



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 44/126 (34%), Positives = 65/126 (51%), Gaps = 3/126 (2%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLT--TLPSEFCGLTHLVKLDLSKNKLRQL 450
           L+L ++ LN +P +   +L    +LDL+ N L   +LP  F  LT L  L LS N    L
Sbjct: 91  LNLGMNRLNTLP-RGFGSLPALEVLDLTYNNLNENSLPGNFFYLTTLRALYLSDNDFEIL 149

Query: 451 PADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG-DCLDEKQ 627
           P D G+L  LQ L L +N L++LP    +L  LK L ++ N L  +  ++   D   +KQ
Sbjct: 150 PPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQ 209

Query: 628 CKQCAN 645
             +  N
Sbjct: 210 IFKAEN 215



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
 Frame = +1

Query: 292 SDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQ--LPADFG 465
           + + E+P  ++++L K   L+L  N+L TLP  F  L  L  LDL+ N L +  LP +F 
Sbjct: 73  NQIEELPT-QISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLNENSLPGNFF 131

Query: 466 RLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            L  L+ L L +N    LP    +L  L+ L L+DN L
Sbjct: 132 YLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDL 169


  Database: RefSeq49_BP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 17,681,374
  Number of sequences in database:  33,088
  
Lambda     K      H
   0.315    0.132    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33088
Number of Hits to DB: 34,233,018
Number of extensions: 810096
Number of successful extensions: 5667
Number of sequences better than 1.0e-05: 74
Number of HSP's gapped: 5265
Number of HSP's successfully gapped: 210
Length of query: 415
Length of database: 17,681,374
Length adjustment: 105
Effective length of query: 310
Effective length of database: 14,207,134
Effective search space: 4404211540
Effective search space used: 4404211540
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 35 (18.1 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-008867
         (1245 letters)

Database: RefSeq49_CP.fasta 
           33,336 sequences; 18,874,504 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|XP_548200.2| PREDICTED: similar to CG3408-PA [Canis familiar...   252   4e-79
Alignment   gi|XP_538584.2| PREDICTED: similar to CCR4-NOT transcription co...    73   5e-13
Alignment   gi|XP_547338.2| PREDICTED: similar to leucine rich repeat conta...    73   5e-13
Alignment   gi|XP_864622.1| PREDICTED: similar to Leucine-rich repeat prote...    72   8e-13
Alignment   gi|XP_857276.1| PREDICTED: similar to CCR4-NOT transcription co...    69   9e-12
Alignment   gi|XP_857234.1| PREDICTED: similar to CCR4-NOT transcription co...    69   9e-12
Alignment   gi|XP_544939.1| PREDICTED: similar to CCR4-NOT transcription co...    69   9e-12
Alignment   gi|XP_535443.2| PREDICTED: similar to CG3040-PA [Canis familiar...    69   1e-11
Alignment   gi|XP_540770.2| PREDICTED: similar to leucine rich repeat and d...    67   4e-11
Alignment   gi|XP_862302.1| PREDICTED: similar to leucine rich repeat and d...    67   4e-11

>ref|XP_548200.2| PREDICTED: similar to CG3408-PA [Canis familiaris].
          Length = 317

 Score =  252 bits (644), Expect(3) = 4e-79
 Identities = 128/140 (91%), Positives = 132/140 (94%)
 Frame = +1

Query: 187 PGAGTRSAGVTMTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCN 366
           P +  R AGVTMTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAAL KATILDLSCN
Sbjct: 160 PPSRDRCAGVTMTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALPKATILDLSCN 219

Query: 367 KLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKS 546
           KLT+LP+EFCGLTHLVKLDLSKNKL+QLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKS
Sbjct: 220 KLTSLPAEFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKS 279

Query: 547 LKWLDLKDNPLDPVLAKVAG 606
           LKWLDLKDNPLDP LAK  G
Sbjct: 280 LKWLDLKDNPLDPALAKWLG 299



 Score = 56.6 bits (135), Expect(3) = 4e-79
 Identities = 32/50 (64%), Positives = 36/50 (72%), Gaps = 1/50 (2%)
 Frame = +2

Query: 2   RKWSSSRRHRWERGAGLRVRPAGGRS-AVISHLRRRGT*ALSVECASPQS 148
           RKWSSSRRHRWERGAGLRV+  GGR+   +S LRRR + A     ASP S
Sbjct: 98  RKWSSSRRHRWERGAGLRVQREGGRADGGVSRLRRRSS-ARCRLAASPPS 146



 Score = 26.9 bits (58), Expect(3) = 4e-79
 Identities = 14/23 (60%), Positives = 14/23 (60%)
 Frame = +3

Query: 132 ARPLSPRAASQPFSCPSEPRGRD 200
           A P S  AASQP   PSEP  RD
Sbjct: 142 ASPPSRPAASQPLFGPSEPPSRD 164


>ref|XP_538584.2| PREDICTED: similar to CCR4-NOT transcription complex, subunit 6
           isoform 1 [Canis familiaris].
          Length = 557

 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 41/86 (47%), Positives = 54/86 (62%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L +L+  T L LS N L+ +PS+   L +LV LDLS NK+R LPA+ G +V+L+ L L N
Sbjct: 47  LWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNN 106

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPL 579
           N L  LP    +L  L+ L LK NPL
Sbjct: 107 NLLRVLPFELGKLFQLQTLGLKGNPL 132



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 29/71 (40%), Positives = 43/71 (60%)
 Frame = +1

Query: 367 KLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKS 546
           K+ +L S    LTHL  L LS N L ++P+D  +L NL +LDL +N++ +LP     + S
Sbjct: 39  KVRSLSSSLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVS 98

Query: 547 LKWLDLKDNPL 579
           L+ L L +N L
Sbjct: 99  LRELHLNNNLL 109



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 32/78 (41%), Positives = 45/78 (57%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L LS + L+ +P  ++A L     LDLS NK+ +LP+E   +  L +L L+ N LR LP 
Sbjct: 56  LHLSDNSLSRIP-SDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPF 114

Query: 457 DFGRLVNLQHLDLLNNRL 510
           + G+L  LQ L L  N L
Sbjct: 115 ELGKLFQLQTLGLKGNPL 132


>ref|XP_547338.2| PREDICTED: similar to leucine rich repeat containing 40 [Canis
           familiaris].
          Length = 555

 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 44/112 (39%), Positives = 66/112 (58%), Gaps = 2/112 (1%)
 Frame = +1

Query: 277 LDLSLSDLNEVP--VKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQL 450
           LD+  + L  +P  ++EL  L K   L++S NKL  LP E   L +L  L L  N+L ++
Sbjct: 63  LDIHDNQLTSLPSAIRELENLQK---LNVSHNKLQILPEEITNLRNLKGLYLQHNELTRI 119

Query: 451 PADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
           P  F +L NL+ LD+ NNRL T+P SF+ L SL  L++  N L  +  +++G
Sbjct: 120 PEGFEQLFNLEDLDISNNRLTTVPASFSSLSSLVRLNISSNQLKSLPVEISG 171



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 38/101 (37%), Positives = 61/101 (60%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L  ++L  +P +    L     LD+S N+LTT+P+ F  L+ LV+L++S N+L+ LP 
Sbjct: 109 LYLQHNELTRIP-EGFEQLFNLEDLDISNNRLTTVPASFSSLSSLVRLNISSNQLKSLPV 167

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
           +   +  L+HLD  +N L T+P   A ++SL+ L L+ N L
Sbjct: 168 EISGMKRLKHLDCNSNLLETVPPELANMESLELLYLRRNKL 208



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 41/118 (34%), Positives = 68/118 (57%)
 Frame = +1

Query: 250 LRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLS 429
           +R+  +  +L++S + L  +P +E+  L     L L  N+LT +P  F  L +L  LD+S
Sbjct: 77  IRELENLQKLNVSHNKLQILP-EEITNLRNLKGLYLQHNELTRIPEGFEQLFNLEDLDIS 135

Query: 430 KNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
            N+L  +PA F  L +L  L++ +N+L +LPV  + +K LK LD   N L+ V  ++A
Sbjct: 136 NNRLTTVPASFSSLSSLVRLNISSNQLKSLPVEISGMKRLKHLDCNSNLLETVPPELA 193



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 43/126 (34%), Positives = 59/126 (46%), Gaps = 23/126 (18%)
 Frame = +1

Query: 292 SDLNEVPVKELAALSKATILDLSCNKLTTLPS-----------------EFCGLTHL--- 411
           S+L E    ELA +    +L L  NKL  LP                  E  G  HL   
Sbjct: 182 SNLLETVPPELANMESLELLYLRRNKLRFLPEFPSCRLLKELHVGENQIEILGPEHLKHL 241

Query: 412 ---VKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
              + LDL  NKLR +P +   L +L+ LDL NN + +LP S  +L  LK+L L+ NPL 
Sbjct: 242 NSILVLDLRDNKLRSVPDEITLLQSLERLDLSNNDISSLPCSLGKL-PLKFLALEGNPLR 300

Query: 583 PVLAKV 600
            +  ++
Sbjct: 301 TIRREI 306



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 31/104 (29%), Positives = 53/104 (50%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           ++ S + L E+P + +      + ++LS NKL+ +  E C L  L  LDL  N L  LP 
Sbjct: 383 VNFSKNQLCEIPKRIVELKEMVSDVNLSFNKLSFISLELCMLQKLTFLDLRNNFLNSLPE 442

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
           +   L+ LQ ++L  NR   LP     + +L+ + + +N +  V
Sbjct: 443 EMESLIRLQTINLSFNRFKILPDVLYHIPTLETILISNNQVGSV 486



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 31/79 (39%), Positives = 44/79 (55%)
 Frame = +1

Query: 343 TILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLP 522
           T L LS N+L +L  +   L  L  LD+  N+L  LP+    L NLQ L++ +N+L  LP
Sbjct: 38  TKLILSSNQLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLQILP 97

Query: 523 VSFAQLKSLKWLDLKDNPL 579
                L++LK L L+ N L
Sbjct: 98  EEITNLRNLKGLYLQHNEL 116



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 37/105 (35%), Positives = 56/105 (53%), Gaps = 1/105 (0%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L++S + L  +PV E++ + +   LD + N L T+P E   +  L  L L +NKLR LP 
Sbjct: 155 LNISSNQLKSLPV-EISGMKRLKHLDCNSNLLETVPPELANMESLELLYLRRNKLRFLP- 212

Query: 457 DFGRLVNLQHLDLLNNRLVTL-PVSFAQLKSLKWLDLKDNPLDPV 588
           +F     L+ L +  N++  L P     L S+  LDL+DN L  V
Sbjct: 213 EFPSCRLLKELHVGENQIEILGPEHLKHLNSILVLDLRDNKLRSV 257


>ref|XP_864622.1| PREDICTED: similar to Leucine-rich repeat protein SHOC-2
           (Ras-binding protein Sur-8) isoform 3 [Canis
           familiaris].
          Length = 605

 Score = 72.4 bits (176), Expect = 8e-13
 Identities = 46/126 (36%), Positives = 69/126 (54%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           EL+L+ + L ++P ++++ L    +L LS N L  LP     L  L +LDL +NKL  LP
Sbjct: 406 ELNLATNQLTKIP-EDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLP 464

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAGDCLDEKQCK 633
            +   L +LQ L L NN+L TLP     L +L  L L +N L  +  ++  + LD   C+
Sbjct: 465 NEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGMNPLDACSCQ 524

Query: 634 QCANKV 651
            CAN +
Sbjct: 525 ICANSL 530



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 36/109 (33%), Positives = 66/109 (60%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L++  + +N++P    +     + L++  N+LT+LP +F   T +V+L+L+ N+L ++P 
Sbjct: 360 LNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
           D   LV+L+ L L NN L  LP     L+ L+ LDL++N L+ +  ++A
Sbjct: 420 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIA 468



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 38/77 (49%), Positives = 45/77 (58%)
 Frame = +1

Query: 349 LDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVS 528
           LDLS   +  LPS    LT L +L L  NKL+ LPA+ G LVNL  L L  N L +LP S
Sbjct: 105 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALNENSLTSLPDS 164

Query: 529 FAQLKSLKWLDLKDNPL 579
              LK L+ LDL+ N L
Sbjct: 165 LDNLKKLRMLDLRHNKL 181



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 34/96 (35%), Positives = 55/96 (57%)
 Frame = +1

Query: 316 KELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDL 495
           K++  LSK ++L +  NK+  LP+E   L +L+ LD++ N+L  LP + G    + +LDL
Sbjct: 209 KDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDL 268

Query: 496 LNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
            +N L+ LP +   L SL  L L+ N L  +   +A
Sbjct: 269 QHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLA 304



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 41/115 (35%), Positives = 61/115 (53%), Gaps = 4/115 (3%)
 Frame = +1

Query: 247 NLRDKLDGNE----LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLV 414
           +L D LD  +    LDL  + L E+P   +  L   T L L  N++TT+  +   L+ L 
Sbjct: 160 SLPDSLDNLKKLRMLDLRHNKLREIP-SVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLS 218

Query: 415 KLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            L + +NK++QLPA+ G L NL  LD+ +N+L  LP        +  LDL+ N L
Sbjct: 219 MLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNEL 273



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 37/101 (36%), Positives = 54/101 (53%), Gaps = 4/101 (3%)
 Frame = +1

Query: 283 LSLSDLNEVPVKELAA----LSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQL 450
           LS+  + E  +K+L A    L     LD++ N+L  LP E    T +  LDL  N+L  L
Sbjct: 217 LSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDL 276

Query: 451 PADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDN 573
           P   G L +L  L L  NRL  +P S A+  +L+ L+L++N
Sbjct: 277 PDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENN 317



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 6/157 (3%)
 Frame = +1

Query: 184 SPGAGTRSAGVTMTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSC 363
           +PG   +S+   + K  +K    R++ +   LDLS   ++ +P   +  L++ T L L  
Sbjct: 78  APGTRKKSSNAEVIKELNK---CREE-NSMRLDLSKRSIHILP-SSIKELTQLTELYLYS 132

Query: 364 NKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLK 543
           NKL +LP+E   L +L+ L L++N L  LP     L  L+ LDL +N+L  +P    +L 
Sbjct: 133 NKLQSLPAEVGCLVNLMTLALNENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLD 192

Query: 544 SLKWLDLKDNPLDPV------LAKVAGDCLDEKQCKQ 636
           SL  L L+ N +  V      L+K++   + E + KQ
Sbjct: 193 SLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQ 229



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 38/113 (33%), Positives = 56/113 (49%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           EL L  + L  +P  E+  L     L L+ N LT+LP     L  L  LDL  NKLR++P
Sbjct: 127 ELYLYSNKLQSLPA-EVGCLVNLMTLALNENSLTSLPDSLDNLKKLRMLDLRHNKLREIP 185

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAGDC 612
           +   RL +L  L L  NR+ T+      L  L  L +++N +  + A++   C
Sbjct: 186 SVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELC 238


>ref|XP_857276.1| PREDICTED: similar to CCR4-NOT transcription complex, subunit
           6-like isoform 1 isoform 4 [Canis familiaris].
          Length = 556

 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 40/86 (46%), Positives = 53/86 (61%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L +L+  T L L+ N L+ +P +   L +LV LDLS NKLR LPA+ G +V+L+ L L N
Sbjct: 47  LWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNN 106

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPL 579
           N L  LP    +L  L+ L LK NPL
Sbjct: 107 NLLRVLPYELGRLFQLQTLGLKGNPL 132



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 33/78 (42%), Positives = 45/78 (57%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L+ +P  ++A L     LDLS NKL +LP+E   +  L +L L+ N LR LP 
Sbjct: 56  LHLNDNYLSRIP-PDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNNNLLRVLPY 114

Query: 457 DFGRLVNLQHLDLLNNRL 510
           + GRL  LQ L L  N L
Sbjct: 115 ELGRLFQLQTLGLKGNPL 132



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 27/71 (38%), Positives = 42/71 (59%)
 Frame = +1

Query: 367 KLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKS 546
           ++ +L +    LTHL  L L+ N L ++P D  +L NL +LDL +N+L +LP     + S
Sbjct: 39  RVRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVS 98

Query: 547 LKWLDLKDNPL 579
           L+ L L +N L
Sbjct: 99  LRELLLNNNLL 109


>ref|XP_857234.1| PREDICTED: similar to CCR4-NOT transcription complex, subunit
           6-like isoform 1 isoform 3 [Canis familiaris].
          Length = 551

 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 40/86 (46%), Positives = 53/86 (61%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L +L+  T L L+ N L+ +P +   L +LV LDLS NKLR LPA+ G +V+L+ L L N
Sbjct: 47  LWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNN 106

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPL 579
           N L  LP    +L  L+ L LK NPL
Sbjct: 107 NLLRVLPYELGRLFQLQTLGLKGNPL 132



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 33/78 (42%), Positives = 45/78 (57%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L+ +P  ++A L     LDLS NKL +LP+E   +  L +L L+ N LR LP 
Sbjct: 56  LHLNDNYLSRIP-PDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNNNLLRVLPY 114

Query: 457 DFGRLVNLQHLDLLNNRL 510
           + GRL  LQ L L  N L
Sbjct: 115 ELGRLFQLQTLGLKGNPL 132



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 27/71 (38%), Positives = 42/71 (59%)
 Frame = +1

Query: 367 KLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKS 546
           ++ +L +    LTHL  L L+ N L ++P D  +L NL +LDL +N+L +LP     + S
Sbjct: 39  RVRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVS 98

Query: 547 LKWLDLKDNPL 579
           L+ L L +N L
Sbjct: 99  LRELLLNNNLL 109


>ref|XP_544939.1| PREDICTED: similar to CCR4-NOT transcription complex, subunit
           6-like isoform 1 isoform 1 [Canis familiaris].
          Length = 550

 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 40/86 (46%), Positives = 53/86 (61%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L +L+  T L L+ N L+ +P +   L +LV LDLS NKLR LPA+ G +V+L+ L L N
Sbjct: 47  LWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNN 106

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPL 579
           N L  LP    +L  L+ L LK NPL
Sbjct: 107 NLLRVLPYELGRLFQLQTLGLKGNPL 132



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 33/78 (42%), Positives = 45/78 (57%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L+ +P  ++A L     LDLS NKL +LP+E   +  L +L L+ N LR LP 
Sbjct: 56  LHLNDNYLSRIP-PDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNNNLLRVLPY 114

Query: 457 DFGRLVNLQHLDLLNNRL 510
           + GRL  LQ L L  N L
Sbjct: 115 ELGRLFQLQTLGLKGNPL 132



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 27/71 (38%), Positives = 42/71 (59%)
 Frame = +1

Query: 367 KLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKS 546
           ++ +L +    LTHL  L L+ N L ++P D  +L NL +LDL +N+L +LP     + S
Sbjct: 39  RVRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVS 98

Query: 547 LKWLDLKDNPL 579
           L+ L L +N L
Sbjct: 99  LRELLLNNNLL 109


>ref|XP_535443.2| PREDICTED: similar to CG3040-PA [Canis familiaris].
          Length = 264

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 38/101 (37%), Positives = 54/101 (53%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           +DLS + +  +P   +   +    L L+ NKLT LP E C L  L  L L+ N LR+LP+
Sbjct: 68  IDLSNNKIESLPPVIIGKFTLLKSLSLNNNKLTVLPEELCNLKKLEMLSLNNNHLRELPS 127

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            FG+L  L+ L L  N+L  LP     L+ L  +DL  N +
Sbjct: 128 TFGQLAALKTLSLSGNQLQALPPQLCSLRHLDVVDLSKNQI 168



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 39/95 (41%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
 Frame = +1

Query: 298 LNEVPVKELAALSKATILDLSCNKLTTLPSEFCG-LTHLVKLDLSKNKLRQLPADFGRLV 474
           L E P +     S    +DLS NK+ +LP    G  T L  L L+ NKL  LP +   L 
Sbjct: 51  LTEFPPELQKLTSNLRTIDLSNNKIESLPPVIIGKFTLLKSLSLNNNKLTVLPEELCNLK 110

Query: 475 NLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            L+ L L NN L  LP +F QL +LK L L  N L
Sbjct: 111 KLEMLSLNNNHLRELPSTFGQLAALKTLSLSGNQL 145



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 39/104 (37%), Positives = 59/104 (56%), Gaps = 2/104 (1%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVK--ELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQL 450
           L L+ + L E+P    +LAAL     L LS N+L  LP + C L HL  +DLSKN++R +
Sbjct: 115 LSLNNNHLRELPSTFGQLAALKT---LSLSGNQLQALPPQLCSLRHLDVVDLSKNQIRSI 171

Query: 451 PADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
           P   G L  ++ L+L  N++  + V  +    LK L L++N L+
Sbjct: 172 PDTVGELQVIE-LNLNQNQISQISVKISCCPRLKVLRLEENCLE 214


>ref|XP_540770.2| PREDICTED: similar to leucine rich repeat and death domain
           containing protein isoform 1 isoform 1 [Canis
           familiaris].
          Length = 911

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 44/102 (43%), Positives = 59/102 (57%)
 Frame = +1

Query: 283 LSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADF 462
           LS + L+E+P + L AL   T L ++ N+L TLP     L+ L +LDLS N L  LP + 
Sbjct: 155 LSYNHLSELP-EALGALPSLTFLSVTHNRLQTLPIALGALSTLQRLDLSGNLLDTLPPEI 213

Query: 463 GRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
           G L +L  L+L +NRL  LP S   L+SL+ L L  N L  V
Sbjct: 214 GGLSSLTELNLASNRLQGLPTSLVGLRSLRLLVLHSNLLTSV 255



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 38/95 (40%), Positives = 54/95 (56%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L+ L++   LDLS N L TLP+    +  L  L LS N L +LP   G L +L  L + +
Sbjct: 121 LSGLARLAHLDLSFNSLETLPACIPQMRGLSTLLLSYNHLSELPEALGALPSLTFLSVTH 180

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
           NRL TLP++   L +L+ LDL  N LD +  ++ G
Sbjct: 181 NRLQTLPIALGALSTLQRLDLSGNLLDTLPPEIGG 215



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 42/104 (40%), Positives = 59/104 (56%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L ++ + L  +P+  L ALS    LDLS N L TLP E  GL+ L +L+L+ N+L+ LP 
Sbjct: 176 LSVTHNRLQTLPIA-LGALSTLQRLDLSGNLLDTLPPEIGGLSSLTELNLASNRLQGLPT 234

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
               L +L+ L L +N L ++P     L  L  LDL+DN L  V
Sbjct: 235 SLVGLRSLRLLVLHSNLLTSVPTGLVHLPLLTRLDLRDNQLRDV 278



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 43/112 (38%), Positives = 57/112 (50%), Gaps = 2/112 (1%)
 Frame = +1

Query: 277 LDLSLSDLNEVP--VKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQL 450
           LDLS + L  +P  + ++  LS  T+L LS N L+ LP     L  L  L ++ N+L+ L
Sbjct: 130 LDLSFNSLETLPACIPQMRGLS--TLL-LSYNHLSELPEALGALPSLTFLSVTHNRLQTL 186

Query: 451 PADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
           P   G L  LQ LDL  N L TLP     L SL  L+L  N L  +   + G
Sbjct: 187 PIALGALSTLQRLDLSGNLLDTLPPEIGGLSSLTELNLASNRLQGLPTSLVG 238



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 38/105 (36%), Positives = 54/105 (51%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           LDLS + L+ +P  E+  LS  T L+L+ N+L  LP+   GL  L  L L  N L  +P 
Sbjct: 199 LDLSGNLLDTLP-PEIGGLSSLTELNLASNRLQGLPTSLVGLRSLRLLVLHSNLLTSVPT 257

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVL 591
               L  L  LDL +N+L  +P    +L    ++ L+ NPL   L
Sbjct: 258 GLVHLPLLTRLDLRDNQLRDVP---PELLDAPFVRLQGNPLGEAL 299


>ref|XP_862302.1| PREDICTED: similar to leucine rich repeat and death domain
           containing protein isoform 3 isoform 3 [Canis
           familiaris].
          Length = 894

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 44/102 (43%), Positives = 59/102 (57%)
 Frame = +1

Query: 283 LSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADF 462
           LS + L+E+P + L AL   T L ++ N+L TLP     L+ L +LDLS N L  LP + 
Sbjct: 155 LSYNHLSELP-EALGALPSLTFLSVTHNRLQTLPIALGALSTLQRLDLSGNLLDTLPPEI 213

Query: 463 GRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
           G L +L  L+L +NRL  LP S   L+SL+ L L  N L  V
Sbjct: 214 GGLSSLTELNLASNRLQGLPTSLVGLRSLRLLVLHSNLLTSV 255



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 38/95 (40%), Positives = 54/95 (56%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L+ L++   LDLS N L TLP+    +  L  L LS N L +LP   G L +L  L + +
Sbjct: 121 LSGLARLAHLDLSFNSLETLPACIPQMRGLSTLLLSYNHLSELPEALGALPSLTFLSVTH 180

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
           NRL TLP++   L +L+ LDL  N LD +  ++ G
Sbjct: 181 NRLQTLPIALGALSTLQRLDLSGNLLDTLPPEIGG 215



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 42/104 (40%), Positives = 59/104 (56%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L ++ + L  +P+  L ALS    LDLS N L TLP E  GL+ L +L+L+ N+L+ LP 
Sbjct: 176 LSVTHNRLQTLPIA-LGALSTLQRLDLSGNLLDTLPPEIGGLSSLTELNLASNRLQGLPT 234

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
               L +L+ L L +N L ++P     L  L  LDL+DN L  V
Sbjct: 235 SLVGLRSLRLLVLHSNLLTSVPTGLVHLPLLTRLDLRDNQLRDV 278



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 43/112 (38%), Positives = 57/112 (50%), Gaps = 2/112 (1%)
 Frame = +1

Query: 277 LDLSLSDLNEVP--VKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQL 450
           LDLS + L  +P  + ++  LS  T+L LS N L+ LP     L  L  L ++ N+L+ L
Sbjct: 130 LDLSFNSLETLPACIPQMRGLS--TLL-LSYNHLSELPEALGALPSLTFLSVTHNRLQTL 186

Query: 451 PADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
           P   G L  LQ LDL  N L TLP     L SL  L+L  N L  +   + G
Sbjct: 187 PIALGALSTLQRLDLSGNLLDTLPPEIGGLSSLTELNLASNRLQGLPTSLVG 238



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 38/105 (36%), Positives = 54/105 (51%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           LDLS + L+ +P  E+  LS  T L+L+ N+L  LP+   GL  L  L L  N L  +P 
Sbjct: 199 LDLSGNLLDTLP-PEIGGLSSLTELNLASNRLQGLPTSLVGLRSLRLLVLHSNLLTSVPT 257

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVL 591
               L  L  LDL +N+L  +P    +L    ++ L+ NPL   L
Sbjct: 258 GLVHLPLLTRLDLRDNQLRDVP---PELLDAPFVRLQGNPLGEAL 299


  Database: RefSeq49_CP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,874,504
  Number of sequences in database:  33,336
  
Lambda     K      H
   0.315    0.132    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33336
Number of Hits to DB: 35,749,299
Number of extensions: 824569
Number of successful extensions: 5835
Number of sequences better than 1.0e-05: 61
Number of HSP's gapped: 5494
Number of HSP's successfully gapped: 181
Length of query: 415
Length of database: 18,874,504
Length adjustment: 105
Effective length of query: 310
Effective length of database: 15,374,224
Effective search space: 4766009440
Effective search space used: 4766009440
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 35 (18.1 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-008867
         (1245 letters)

Database: RefSeq49_SP.fasta 
           24,897 sequences; 11,343,932 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|XP_003131627.1| PREDICTED: LOW QUALITY PROTEIN: leucine-rich...   479   e-135
Alignment   gi|XP_003123675.2| PREDICTED: CCR4-NOT transcription complex su...    73   4e-13
Alignment   gi|XP_003129169.1| PREDICTED: CCR4-NOT transcription complex su...    70   2e-12
Alignment   gi|XP_003127976.1| PREDICTED: leucine-rich repeat-containing pr...    67   2e-11
Alignment   gi|XP_003121620.2| PREDICTED: leucine-rich repeat-containing pr...    65   6e-11
Alignment   gi|XP_001927528.1| PREDICTED: leucine-rich repeat protein SHOC-...    65   8e-11
Alignment   gi|XP_003130183.2| PREDICTED: leucine-rich repeat and death dom...    65   1e-10
Alignment   gi|XP_003361200.1| PREDICTED: ras suppressor protein 1-like [Su...    64   2e-10
Alignment   gi|XP_001927723.2| PREDICTED: leucine-rich repeat-containing pr...    62   7e-10
Alignment   gi|NP_001041651.1| insulin-like growth factor-binding protein c...    62   9e-10

>ref|XP_003131627.1| PREDICTED: LOW QUALITY PROTEIN: leucine-rich repeat-containing
            protein 59-like [Sus scrofa].
          Length = 306

 Score =  479 bits (1232), Expect = e-135
 Identities = 250/304 (82%), Positives = 250/304 (82%)
 Frame = +1

Query: 220  MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCG 399
            MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCG
Sbjct: 1    MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCG 60

Query: 400  LTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            LTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLL NRLVTLPVSFAQLKSLKWLDLKDNPL
Sbjct: 61   LTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLXNRLVTLPVSFAQLKSLKWLDLKDNPL 120

Query: 580  DPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEIDREAEKKWEAKQXXX 759
            DPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEIDREAEKKWEAKQ   
Sbjct: 121  DPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEIDREAEKKWEAKQRAK 180

Query: 760  XXXXXXXXXXXXXXXXXXXXXXYDALKAAKREQEKKPKKETNQAXXXXXXXXXXXXXXXX 939
                                  YDALKAAKREQEKKPKKETNQA                
Sbjct: 181  EAQERELRKREKAEEKERRRKEYDALKAAKREQEKKPKKETNQAPKSKSGSRPRKPPPRK 240

Query: 940  XXXXWAVLXXXXXXXXCVAGGLVACRVTELQQQPLCTSVNTIYDNAVRGLRSHDIVQWVL 1119
                WAVL        CVAGGLVACRVTELQQQPLCTSVNTIYDNAVRGLRSHDIVQWVL
Sbjct: 241  HTRSWAVLKLLLLLLLCVAGGLVACRVTELQQQPLCTSVNTIYDNAVRGLRSHDIVQWVL 300

Query: 1120 QTDS 1131
            QTDS
Sbjct: 301  QTDS 304


>ref|XP_003123675.2| PREDICTED: CCR4-NOT transcription complex subunit 6 [Sus scrofa].
          Length = 552

 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 41/86 (47%), Positives = 54/86 (62%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L +L+  T L LS N L+ +PS+   L +LV LDLS NK+R LPA+ G +V+L+ L L N
Sbjct: 47  LWSLTHLTALYLSDNSLSRIPSDIAKLHNLVHLDLSSNKIRSLPAELGNMVSLRELHLNN 106

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPL 579
           N L  LP    +L  L+ L LK NPL
Sbjct: 107 NLLRVLPFELGKLFQLQTLGLKGNPL 132



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 30/71 (42%), Positives = 43/71 (60%)
 Frame = +1

Query: 367 KLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKS 546
           K+ +L S    LTHL  L LS N L ++P+D  +L NL HLDL +N++ +LP     + S
Sbjct: 39  KVRSLSSSLWSLTHLTALYLSDNSLSRIPSDIAKLHNLVHLDLSSNKIRSLPAELGNMVS 98

Query: 547 LKWLDLKDNPL 579
           L+ L L +N L
Sbjct: 99  LRELHLNNNLL 109



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 32/78 (41%), Positives = 45/78 (57%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L LS + L+ +P  ++A L     LDLS NK+ +LP+E   +  L +L L+ N LR LP 
Sbjct: 56  LYLSDNSLSRIP-SDIAKLHNLVHLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPF 114

Query: 457 DFGRLVNLQHLDLLNNRL 510
           + G+L  LQ L L  N L
Sbjct: 115 ELGKLFQLQTLGLKGNPL 132


>ref|XP_003129169.1| PREDICTED: CCR4-NOT transcription complex subunit 6-like [Sus
           scrofa].
          Length = 552

 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 50/139 (35%), Positives = 72/139 (51%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L +L+  T L L+ N L+ +P +   L +LV LDLS NKLR LPA+ G +V+L+ L L N
Sbjct: 47  LWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNN 106

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQAD 681
           N L  LP    +L  L+ L LK NPL       + D L+  Q      K+L  M     D
Sbjct: 107 NLLRVLPYELGRLFQLQTLGLKGNPL-------SQDILNLYQDPDGTRKLLNFM----LD 155

Query: 682 QERERQRRLEIDREAEKKW 738
               R++R+  ++   + W
Sbjct: 156 NLAGRRKRVHPEQLPPRPW 174



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 33/78 (42%), Positives = 45/78 (57%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L+ +P  ++A L     LDLS NKL +LP+E   +  L +L L+ N LR LP 
Sbjct: 56  LHLNDNYLSRIP-PDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNNNLLRVLPY 114

Query: 457 DFGRLVNLQHLDLLNNRL 510
           + GRL  LQ L L  N L
Sbjct: 115 ELGRLFQLQTLGLKGNPL 132



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 27/71 (38%), Positives = 42/71 (59%)
 Frame = +1

Query: 367 KLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKS 546
           ++ +L +    LTHL  L L+ N L ++P D  +L NL +LDL +N+L +LP     + S
Sbjct: 39  RVRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVS 98

Query: 547 LKWLDLKDNPL 579
           L+ L L +N L
Sbjct: 99  LRELLLNNNLL 109


>ref|XP_003127976.1| PREDICTED: leucine-rich repeat-containing protein 40-like [Sus
           scrofa].
          Length = 602

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 48/138 (34%), Positives = 72/138 (52%), Gaps = 23/138 (16%)
 Frame = +1

Query: 262 LDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKL 441
           +  N+L  SLSD       +L  L   T+LD+  N+LT+LPS    L +L KL++S NKL
Sbjct: 89  ISNNKLQ-SLSD-------DLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKL 140

Query: 442 RQLPAD-----------------------FGRLVNLQHLDLLNNRLVTLPVSFAQLKSLK 552
           + LP +                       F +L NL+ LDL NNRL ++P SF+ L S+ 
Sbjct: 141 KILPEEITNLRNLKGLYLQHNELTCIPEGFEQLFNLEDLDLSNNRLSSIPASFSSLSSVV 200

Query: 553 WLDLKDNPLDPVLAKVAG 606
            L++  N L  + A+++G
Sbjct: 201 RLNISSNQLKSLPAEISG 218



 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 32/77 (41%), Positives = 53/77 (68%)
 Frame = +1

Query: 349 LDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVS 528
           LDLS N+L+++P+ F  L+ +V+L++S N+L+ LPA+   +  L+HLD  +N L T+P  
Sbjct: 179 LDLSNNRLSSIPASFSSLSSVVRLNISSNQLKSLPAEISGMKRLKHLDCNSNLLETIPPE 238

Query: 529 FAQLKSLKWLDLKDNPL 579
            A ++SL+ L L+ N L
Sbjct: 239 LASMESLELLYLRRNKL 255



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 39/118 (33%), Positives = 67/118 (56%)
 Frame = +1

Query: 250 LRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLS 429
           +R+  +  +L++S + L  +P +E+  L     L L  N+LT +P  F  L +L  LDLS
Sbjct: 124 IRELENLQKLNVSHNKLKILP-EEITNLRNLKGLYLQHNELTCIPEGFEQLFNLEDLDLS 182

Query: 430 KNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
            N+L  +PA F  L ++  L++ +N+L +LP   + +K LK LD   N L+ +  ++A
Sbjct: 183 NNRLSSIPASFSSLSSVVRLNISSNQLKSLPAEISGMKRLKHLDCNSNLLETIPPELA 240



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 42/126 (33%), Positives = 60/126 (47%), Gaps = 23/126 (18%)
 Frame = +1

Query: 292 SDLNEVPVKELAALSKATILDLSCNKLTTLPS-----------------EFCGLTHL--- 411
           S+L E    ELA++    +L L  NKL  LP                  E  G  HL   
Sbjct: 229 SNLLETIPPELASMESLELLYLRRNKLRFLPEFPSCKLLKELHVGENQIEMLGAEHLKHL 288

Query: 412 ---VKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
              + LDL  NKL+ +P +   L +L+ LDL NN + +LP S  +L  LK+L L+ NPL 
Sbjct: 289 NSILVLDLRDNKLKSVPDEITLLQSLERLDLSNNDISSLPCSLGKL-HLKFLALEGNPLR 347

Query: 583 PVLAKV 600
            +  ++
Sbjct: 348 TIRREI 353



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 32/104 (30%), Positives = 54/104 (51%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           ++ S + L E+P + +      + ++LS NKL+ +  E C L  L  LDL  N L  LP 
Sbjct: 430 VNFSKNQLCEIPKRIVEMKEMVSDVNLSFNKLSFISLELCMLQKLTFLDLRNNFLNSLPE 489

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
           +   LV LQ ++L  NR   LP    ++ +L+ + + +N +  V
Sbjct: 490 EMESLVRLQTINLSFNRFKILPEVLYRIPTLETILISNNQVGSV 533



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 31/79 (39%), Positives = 44/79 (55%)
 Frame = +1

Query: 343 TILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLP 522
           T L +S NKL +L  +   L  L  LD+  N+L  LP+    L NLQ L++ +N+L  LP
Sbjct: 85  TKLIISNNKLQSLSDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILP 144

Query: 523 VSFAQLKSLKWLDLKDNPL 579
                L++LK L L+ N L
Sbjct: 145 EEITNLRNLKGLYLQHNEL 163


>ref|XP_003121620.2| PREDICTED: leucine-rich repeat-containing protein 57-like [Sus
           scrofa].
          Length = 239

 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 36/101 (35%), Positives = 54/101 (53%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           +DLS + +  +P   +   +    L L+ N+LT LP E C L  L  L L+ N LR+LP+
Sbjct: 43  IDLSSNKIESLPPMIIGKFTLLKSLSLNNNRLTVLPDELCHLKKLETLSLNNNHLRELPS 102

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            FG+L  L+ L +  N+L  LP     L+ L  +DL  N +
Sbjct: 103 TFGQLSALKTLSISGNQLRALPPQLCSLRHLDVVDLSKNQI 143



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 37/95 (38%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
 Frame = +1

Query: 298 LNEVPVKELAALSKATILDLSCNKLTTLPSEFCG-LTHLVKLDLSKNKLRQLPADFGRLV 474
           L E P +     S    +DLS NK+ +LP    G  T L  L L+ N+L  LP +   L 
Sbjct: 26  LTEFPSELQKLTSNLRTIDLSSNKIESLPPMIIGKFTLLKSLSLNNNRLTVLPDELCHLK 85

Query: 475 NLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            L+ L L NN L  LP +F QL +LK L +  N L
Sbjct: 86  KLETLSLNNNHLRELPSTFGQLSALKTLSISGNQL 120



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 36/102 (35%), Positives = 56/102 (54%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L E+P      LS    L +S N+L  LP + C L HL  +DLSKN++R +P 
Sbjct: 90  LSLNNNHLRELP-STFGQLSALKTLSISGNQLRALPPQLCSLRHLDVVDLSKNQIRSIPD 148

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
             G L  ++ L+L  N++  + V  +    LK L L++N L+
Sbjct: 149 IVGELQVIE-LNLNQNQISQISVKISCCPRLKVLRLEENCLE 189


>ref|XP_001927528.1| PREDICTED: leucine-rich repeat protein SHOC-2 [Sus scrofa].
          Length = 582

 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 36/109 (33%), Positives = 66/109 (60%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L++  + +N++P    +     + L++  N+LT+LP +F   T +V+L+L+ N+L ++P 
Sbjct: 360 LNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
           D   LV+L+ L L NN L  LP     L+ L+ LDL++N L+ +  ++A
Sbjct: 420 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIA 468



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 38/77 (49%), Positives = 45/77 (58%)
 Frame = +1

Query: 349 LDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVS 528
           LDLS   +  LPS    LT L +L L  NKL+ LPA+ G LVNL  L L  N L +LP S
Sbjct: 105 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 164

Query: 529 FAQLKSLKWLDLKDNPL 579
              LK L+ LDL+ N L
Sbjct: 165 LDNLKKLRMLDLRHNKL 181



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 44/100 (44%), Positives = 54/100 (54%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L LS + L ++P   L  L K   LDL  NKL +LP+E   L  L KL L+ N+L  LP 
Sbjct: 430 LILSNNLLKKLP-HGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPR 488

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNP 576
             G L NL HL L  N L  LP     L++L+ L L DNP
Sbjct: 489 GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNP 528



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 34/96 (35%), Positives = 55/96 (57%)
 Frame = +1

Query: 316 KELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDL 495
           K++  LSK ++L +  NK+  LP+E   L +L+ LD++ N+L  LP + G    + +LDL
Sbjct: 209 KDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDL 268

Query: 496 LNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
            +N L+ LP +   L SL  L L+ N L  +   +A
Sbjct: 269 QHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLA 304



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 41/115 (35%), Positives = 61/115 (53%), Gaps = 4/115 (3%)
 Frame = +1

Query: 247 NLRDKLDGNE----LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLV 414
           +L D LD  +    LDL  + L E+P   +  L   T L L  N++TT+  +   L+ L 
Sbjct: 160 SLPDSLDNLKKLRMLDLRHNKLREIP-SVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLS 218

Query: 415 KLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            L + +NK++QLPA+ G L NL  LD+ +N+L  LP        +  LDL+ N L
Sbjct: 219 MLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNEL 273



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 40/102 (39%), Positives = 57/102 (55%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           EL+L+ + L ++P ++++ L    +L LS N L  LP     L  L +LDL +NKL  LP
Sbjct: 406 ELNLATNQLTKIP-EDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLP 464

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            +   L +LQ L L NN+L TLP     L +L  L L +N L
Sbjct: 465 NEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLL 506



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 37/103 (35%), Positives = 58/103 (56%)
 Frame = +1

Query: 271 NELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQL 450
           ++L++  + L  +P+ +    +    L+L+ N+LT +P +  GL  L  L LS N L++L
Sbjct: 382 SKLNMKDNQLTSLPL-DFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKL 440

Query: 451 PADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
           P   G L  L+ LDL  N+L +LP   A LK L+ L L +N L
Sbjct: 441 PHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQL 483



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 37/101 (36%), Positives = 54/101 (53%), Gaps = 4/101 (3%)
 Frame = +1

Query: 283 LSLSDLNEVPVKELAA----LSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQL 450
           LS+  + E  +K+L A    L     LD++ N+L  LP E    T +  LDL  N+L  L
Sbjct: 217 LSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDL 276

Query: 451 PADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDN 573
           P   G L +L  L L  NRL  +P S A+  +L+ L+L++N
Sbjct: 277 PDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENN 317



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 50/157 (31%), Positives = 81/157 (51%), Gaps = 6/157 (3%)
 Frame = +1

Query: 184 SPGAGTRSAGVTMTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSC 363
           +PG   +S+   + K  +K    R++ +   LDLS   ++ +P   +  L++ T L L  
Sbjct: 78  APGTRKKSSNAEVIKELNK---CREE-NSMRLDLSKRSIHILP-SSIKELTQLTELYLYS 132

Query: 364 NKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLK 543
           NKL +LP+E   L +L+ L LS+N L  LP     L  L+ LDL +N+L  +P    +L 
Sbjct: 133 NKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLD 192

Query: 544 SLKWLDLKDNPLDPV------LAKVAGDCLDEKQCKQ 636
           SL  L L+ N +  V      L+K++   + E + KQ
Sbjct: 193 SLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQ 229



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 39/113 (34%), Positives = 56/113 (49%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           EL L  + L  +P  E+  L     L LS N LT+LP     L  L  LDL  NKLR++P
Sbjct: 127 ELYLYSNKLQSLPA-EVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIP 185

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAGDC 612
           +   RL +L  L L  NR+ T+      L  L  L +++N +  + A++   C
Sbjct: 186 SVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELC 238



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           LD++ + L  +P KE+   ++ T LDL  N+L  LP     L+ L +L L  N+L  +P 
Sbjct: 243 LDVAHNQLEHLP-KEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPR 301

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVS-FAQLKSLKWLDLKDN 573
              +   L+ L+L NN + TLP S  + L  L  L L  N
Sbjct: 302 SLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARN 341


>ref|XP_003130183.2| PREDICTED: leucine-rich repeat and death domain-containing protein
           LOC401387 [Sus scrofa].
          Length = 855

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 32/96 (33%), Positives = 58/96 (60%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           LDL  + + ++P   ++ +    +L L CNKL T P E C L +L  LDLS+N+++ +P 
Sbjct: 534 LDLGKNKIKKIP-PSISNMVSLHVLILCCNKLETFPIEVCTLENLQVLDLSENQIQNIPP 592

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDL 564
           +   L  +Q L++ +N+ +  P+   QL+SL+ L++
Sbjct: 593 EICNLKGIQKLNISSNQFIYFPIELCQLQSLEELNI 628



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 35/104 (33%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVK--ELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQ 447
           +L++S +     P++  +L +L +  I  ++  KLT LP E C +  L +LD+S N +R+
Sbjct: 602 KLNISSNQFIYFPIELCQLQSLEELNISQINGRKLTRLPEELCNMIQLKELDISNNAIRE 661

Query: 448 LPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
           +P   G L +L  L   NN++  LP S   L +L+ L+L  N L
Sbjct: 662 MPRSIGELRSLVSLKAYNNQIRYLPPSXLSLNALQQLNLSGNNL 705



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 38/108 (35%), Positives = 59/108 (54%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L+L+ + L  +P   L++L K   L+L  N+LT  P   C L  L+ L+L+ N +  LP 
Sbjct: 258 LNLAKNKLRHIP-DTLSSLKKLRGLNLEYNQLTIFPKALCFLPKLISLNLTGNLISSLPK 316

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKV 600
           +   L NL+ L L +N+L  L V   +L  +K L L DN L+ +  K+
Sbjct: 317 EIKELKNLEKLLLDHNKLTFLAVEIFRLLRMKELQLTDNKLEVISHKI 364



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 30/97 (30%), Positives = 55/97 (56%)
 Frame = +1

Query: 298 LNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVN 477
           ++E+P ++++   +   L+ + NKL       C L +L  LDL KNK++++P     +V+
Sbjct: 495 ISEIP-EDISFSKQLLHLEFNENKLLIFSEHLCSLINLEYLDLGKNKIKKIPPSISNMVS 553

Query: 478 LQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
           L  L L  N+L T P+    L++L+ LDL +N +  +
Sbjct: 554 LHVLILCCNKLETFPIEVCTLENLQVLDLSENQIQNI 590



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 34/114 (29%), Positives = 61/114 (53%)
 Frame = +1

Query: 238 KGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVK 417
           KG +  D L    L +  + L+ +P  E+  L     L++S N+++ +P E   L ++ +
Sbjct: 176 KGVDPSDLLGLEILSMKENGLSSLP-SEIQLLHNLKTLNVSHNQISHIPKELSQLGNIRQ 234

Query: 418 LDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
           L L+ N +   P+    L NL+ L+L  N+L  +P + + LK L+ L+L+ N L
Sbjct: 235 LFLNNNCIEGSPSGLESLGNLEILNLAKNKLRHIPDTLSSLKKLRGLNLEYNQL 288



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 43/148 (29%), Positives = 71/148 (47%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L+L  + L   P K L  L K   L+L+ N +++LP E   L +L KL L  NKL  L  
Sbjct: 281 LNLEYNQLTIFP-KALCFLPKLISLNLTGNLISSLPKEIKELKNLEKLLLDHNKLTFLAV 339

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAGDCLDEKQCKQ 636
           +  RL+ ++ L L +N+L  +       + L+ L L  N L  V   ++  C+  +    
Sbjct: 340 EIFRLLRMKELQLTDNKLEVISHKIENFRELRILVLDKNLLKDVPENIS-HCVMLEFLSL 398

Query: 637 CANKVLQHMKAVQADQERERQRRLEIDR 720
             NK+ +  K +    + +  R+L I+R
Sbjct: 399 SDNKLTELPKNI---HKLKNLRKLHINR 423



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 28/86 (32%), Positives = 41/86 (47%)
 Frame = +1

Query: 316 KELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDL 495
           + L +L     LDL  NK+  +P     +  L  L L  NKL   P +   L NLQ LDL
Sbjct: 523 EHLCSLINLEYLDLGKNKIKKIPPSISNMVSLHVLILCCNKLETFPIEVCTLENLQVLDL 582

Query: 496 LNNRLVTLPVSFAQLKSLKWLDLKDN 573
             N++  +P     LK ++ L++  N
Sbjct: 583 SENQIQNIPPEICNLKGIQKLNISSN 608


>ref|XP_003361200.1| PREDICTED: ras suppressor protein 1-like [Sus scrofa].
          Length = 237

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 45/114 (39%), Positives = 62/114 (54%), Gaps = 5/114 (4%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLT--TLPSEFCGLTHLVKLDLSKNKLRQL 450
           L+L ++ LN +P +   +L    +LDL+ N L+  +LP  F  LT L  L LS N    L
Sbjct: 121 LNLGMNRLNTLP-RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEIL 179

Query: 451 PADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDN---PLDPVLAKVA 603
           P D G+L  LQ L L +N L++LP    +L  LK L ++ N    L P L KVA
Sbjct: 180 PPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGKVA 233



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 36/83 (43%), Positives = 47/83 (56%)
 Frame = +1

Query: 331 LSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRL 510
           L+  T L LS NKLTT+P     L +L  L+   N++ +LP     L  L+HL+L  NRL
Sbjct: 69  LAHITQLVLSHNKLTTVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRL 128

Query: 511 VTLPVSFAQLKSLKWLDLKDNPL 579
            TLP  F  L +L+ LDL  N L
Sbjct: 129 NTLPRGFGSLPALEVLDLTYNNL 151



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 38/105 (36%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           +L LS + L  VP   +A L    +L+   N++  LP++   L  L  L+L  N+L  LP
Sbjct: 74  QLVLSHNKLTTVP-PNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 132

Query: 454 ADFGRLVNLQHLDLLNNRLV--TLPVSFAQLKSLKWLDLKDNPLD 582
             FG L  L+ LDL  N L   +LP +F  L +L+ L L DN  +
Sbjct: 133 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFE 177


>ref|XP_001927723.2| PREDICTED: leucine-rich repeat-containing protein 1 [Sus scrofa].
          Length = 524

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 42/106 (39%), Positives = 56/106 (52%)
 Frame = +1

Query: 262 LDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKL 441
           LDGN+L       +E+P +E+  L     LD+S N+L  LP E  GLT L  L +S+N L
Sbjct: 204 LDGNQL-------SELP-QEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLL 255

Query: 442 RQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
             LP   G+L  L  L +  NRL  LP +    +SL  L L +N L
Sbjct: 256 EMLPDGIGKLKKLSILKVDQNRLTQLPEAIGDCESLTELVLTENRL 301



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 45/123 (36%), Positives = 65/123 (52%)
 Frame = +1

Query: 244 GNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLD 423
           GNL++ L    LD+S + L  +P +E++ L+  T L +S N L  LP     L  L  L 
Sbjct: 217 GNLKNLLC---LDVSENRLERLP-EEISGLTSLTDLVISQNLLEMLPDGIGKLKKLSILK 272

Query: 424 LSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
           + +N+L QLP   G   +L  L L  NRL+TLP S  +LK L  L+   N L  +  ++ 
Sbjct: 273 VDQNRLTQLPEAIGDCESLTELVLTENRLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIG 332

Query: 604 GDC 612
           G C
Sbjct: 333 GCC 335



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 43/133 (32%), Positives = 68/133 (51%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           ELDL  +++  +P + + AL     L L  N+L+ LP E   L +L+ LD+S+N+L +LP
Sbjct: 178 ELDLGNNEIYNLP-ESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLP 236

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAGDCLDEKQCK 633
            +   L +L  L +  N L  LP    +LK L  L +  N L   L +  GDC    +  
Sbjct: 237 EEISGLTSLTDLVISQNLLEMLPDGIGKLKKLSILKVDQNRLTQ-LPEAIGDCESLTELV 295

Query: 634 QCANKVLQHMKAV 672
              N++L   K++
Sbjct: 296 LTENRLLTLPKSI 308



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 40/106 (37%), Positives = 57/106 (53%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           EL L+ + L  +P K +  L K + L+   NKL +LP E  G   L    +  N+L ++P
Sbjct: 293 ELVLTENRLLTLP-KSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIP 351

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVL 591
           A+  +   L  LD+  NRL+ LP+S   LK LK L L DN   P+L
Sbjct: 352 AEVSQATELHVLDVAGNRLLHLPLSLTTLK-LKALWLSDNQSQPLL 396



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 34/87 (39%), Positives = 44/87 (50%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L  L +   LDL  N++  LP     L HL  L L  N+L +LP + G L NL  LD+  
Sbjct: 170 LTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSE 229

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPLD 582
           NRL  LP   + L SL  L +  N L+
Sbjct: 230 NRLERLPEEISGLTSLTDLVISQNLLE 256



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 37/109 (33%), Positives = 58/109 (53%), Gaps = 1/109 (0%)
 Frame = +1

Query: 280 DLSLS-DLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           DL +S +L E+    +  L K +IL +  N+LT LP        L +L L++N+L  LP 
Sbjct: 247 DLVISQNLLEMLPDGIGKLKKLSILKVDQNRLTQLPEAIGDCESLTELVLTENRLLTLPK 306

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
             G+L  L +L+   N+LV+LP       SL    ++DN L  + A+V+
Sbjct: 307 SIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVS 355



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 40/121 (33%), Positives = 54/121 (44%), Gaps = 25/121 (20%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           ELD+S +D+ E+P + ++      I D S N LT LP  F  L +L  L ++   L+ LP
Sbjct: 86  ELDVSRNDIPEIP-ESISFCKALQIADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLP 144

Query: 454 ADFGRLVNL-----------------------QHLDLLNNRLVTLPVSFAQLKSLK--WL 558
            + G L NL                       + LDL NN +  LP S   L  LK  WL
Sbjct: 145 ENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWL 204

Query: 559 D 561
           D
Sbjct: 205 D 205


>ref|NP_001041651.1| insulin-like growth factor-binding protein complex acid labile
           subunit [Sus scrofa].
          Length = 606

 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 44/109 (40%), Positives = 64/109 (58%), Gaps = 3/109 (2%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTL-PSEFCGLTHLVKLDLSKNKLRQL 450
           +L+L  + L  +P      L+    L L+ NKLT L P+ FCGL  L +LDLS+N LR +
Sbjct: 174 DLNLGWNSLAVLPDTAFHGLANLRELVLAGNKLTYLQPALFCGLGELRELDLSRNALRSV 233

Query: 451 PAD-FGRLVNLQHLDLLNNRLVTL-PVSFAQLKSLKWLDLKDNPLDPVL 591
            A+ F +L  LQ L L +N L  + P +F  +K+L+WLDL  N +  +L
Sbjct: 234 KANVFVKLPKLQKLYLDHNLLAAVAPGAFLGMKALRWLDLSHNRVGGLL 282



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 40/105 (38%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCG-LTHLVKLDLSKNKLRQL 450
           ELDL+ + L  +P +    L K   L LS N+L+ LP++  G L     LD+S N+L+ L
Sbjct: 438 ELDLTANRLTHLPGRLFQGLGKLEYLLLSRNRLSALPADALGPLQRTFWLDVSHNRLQAL 497

Query: 451 P-ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
           P A    L  L++L L NN L T      Q   L+ L L+ NP D
Sbjct: 498 PEAVLAPLGQLRYLSLRNNSLRTF---VPQPLGLERLWLEGNPWD 539


  Database: RefSeq49_SP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 11,343,932
  Number of sequences in database:  24,897
  
Lambda     K      H
   0.315    0.132    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 24897
Number of Hits to DB: 22,251,957
Number of extensions: 543281
Number of successful extensions: 3741
Number of sequences better than 1.0e-05: 54
Number of HSP's gapped: 3500
Number of HSP's successfully gapped: 126
Length of query: 415
Length of database: 11,343,932
Length adjustment: 101
Effective length of query: 314
Effective length of database: 8,829,335
Effective search space: 2772411190
Effective search space used: 2772411190
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 34 (17.7 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-008867
         (1245 letters)

Database: RefSeq49_MP.fasta 
           30,036 sequences; 15,617,559 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_598568.1| leucine-rich repeat-containing protein 59 [Mus ...   444   e-125
Alignment   gi|NP_077156.2| leucine-rich repeat-containing protein 40 [Mus ...    72   9e-13
Alignment   gi|NP_997649.1| CCR4-NOT transcription complex subunit 6 [Mus m...    71   2e-12
Alignment   gi|NP_073145.1| p53-induced protein with a death domain [Mus mu...    68   2e-11
Alignment   gi|NP_001153081.1| leucine-rich repeat-containing protein 57 is...    67   3e-11
Alignment   gi|NP_001153084.1| leucine-rich repeat-containing protein 57 is...    67   4e-11
Alignment   gi|NP_001153082.1| leucine-rich repeat-containing protein 57 is...    67   4e-11
Alignment   gi|NP_079933.2| leucine-rich repeat-containing protein 57 isofo...    67   4e-11
Alignment   gi|NP_001074827.1| leucine-rich repeat-containing protein 7 [Mu...    66   5e-11
Alignment   gi|NP_001139520.1| leucine-rich repeat-containing protein 1 iso...    66   5e-11

>ref|NP_598568.1| leucine-rich repeat-containing protein 59 [Mus musculus].
          Length = 307

 Score =  444 bits (1142), Expect = e-125
 Identities = 232/305 (76%), Positives = 243/305 (79%), Gaps = 1/305 (0%)
 Frame = +1

Query: 220  MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCG 399
            MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAAL KAT+LDLSCNKL+TLPS+FCG
Sbjct: 1    MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALPKATVLDLSCNKLSTLPSDFCG 60

Query: 400  LTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            LTHLVKLDLSKNKL+QLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLK+LKWLDLKDNPL
Sbjct: 61   LTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKNLKWLDLKDNPL 120

Query: 580  DPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEIDREAEKKWEAKQXXX 759
            DPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLE++REAEKK EAKQ   
Sbjct: 121  DPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEVEREAEKKREAKQQAK 180

Query: 760  XXXXXXXXXXXXXXXXXXXXXXYDALKAAKREQEKKPKKETNQAXXXXXXXXXXXXXXXX 939
                                  YDA KA+KREQEKKPKKE NQA                
Sbjct: 181  EAKERELRKREKAEEKERRRKEYDAQKASKREQEKKPKKEANQAPKSKSGSRPRKPPPRK 240

Query: 940  XXXXWAVL-XXXXXXXXCVAGGLVACRVTELQQQPLCTSVNTIYDNAVRGLRSHDIVQWV 1116
                WAVL         CVAGGLV CRVT L QQPLCTSVNTIYDNAV+GLR H+I+QWV
Sbjct: 241  HTRSWAVLKVLLLLLLLCVAGGLVVCRVTGLHQQPLCTSVNTIYDNAVQGLRHHEILQWV 300

Query: 1117 LQTDS 1131
            LQTDS
Sbjct: 301  LQTDS 305


>ref|NP_077156.2| leucine-rich repeat-containing protein 40 [Mus musculus].
          Length = 602

 Score = 72.0 bits (175), Expect = 9e-13
 Identities = 48/137 (35%), Positives = 78/137 (56%), Gaps = 5/137 (3%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L  ++L  +P +    LS    LDLS N+L T+P++F  L+ L++L+LS N+L+ LPA
Sbjct: 156 LHLQHNELTCIP-EGFEHLSCLEDLDLSSNRLATVPADFALLSSLLRLNLSSNQLKNLPA 214

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDN-----PLDPVLAKVAGDCLDE 621
           +  R+  L+HLD   N L T+P     ++SL+ L L+ N     P  P   ++    L E
Sbjct: 215 EISRMKRLKHLDCDANLLETVPPDVGSMESLELLYLRRNKLRVLPEFPSCRQLKELHLAE 274

Query: 622 KQCKQCANKVLQHMKAV 672
            Q ++   + LQH++A+
Sbjct: 275 NQIEKLGAEHLQHLQAI 291



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 45/116 (38%), Positives = 64/116 (55%)
 Frame = +1

Query: 256 DKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKN 435
           D+ D  +L +S + L  +   +L  L   T+LD+  N+LT+LPS    L +L KL++S N
Sbjct: 80  DQTDLTKLIISSNKLQSLS-DDLRLLPALTVLDIHDNQLTSLPSAIRELDNLQKLNVSHN 138

Query: 436 KLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
           KL+ LP +   L NL+ L L +N L  +P  F  L  L+ LDL  N L  V A  A
Sbjct: 139 KLKILPEEITSLKNLRTLHLQHNELTCIPEGFEHLSCLEDLDLSSNRLATVPADFA 194



 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 41/105 (39%), Positives = 62/105 (59%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           +L++S + L  +P +E+ +L     L L  N+LT +P  F  L+ L  LDLS N+L  +P
Sbjct: 132 KLNVSHNKLKILP-EEITSLKNLRTLHLQHNELTCIPEGFEHLSCLEDLDLSSNRLATVP 190

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
           ADF  L +L  L+L +N+L  LP   +++K LK LD   N L+ V
Sbjct: 191 ADFALLSSLLRLNLSSNQLKNLPAEISRMKRLKHLDCDANLLETV 235



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 44/111 (39%), Positives = 62/111 (55%), Gaps = 2/111 (1%)
 Frame = +1

Query: 277 LDLSLSDLNEVP--VKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQL 450
           LD+  + L  +P  ++EL  L K   L++S NKL  LP E   L +L  L L  N+L  +
Sbjct: 110 LDIHDNQLTSLPSAIRELDNLQK---LNVSHNKLKILPEEITSLKNLRTLHLQHNELTCI 166

Query: 451 PADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
           P  F  L  L+ LDL +NRL T+P  FA L SL  L+L  N L  + A+++
Sbjct: 167 PEGFEHLSCLEDLDLSSNRLATVPADFALLSSLLRLNLSSNQLKNLPAEIS 217



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 42/131 (32%), Positives = 60/131 (45%), Gaps = 23/131 (17%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPS-----------------EFCGLT 405
           LD   + L  VP  ++ ++    +L L  NKL  LP                  E  G  
Sbjct: 225 LDCDANLLETVP-PDVGSMESLELLYLRRNKLRVLPEFPSCRQLKELHLAENQIEKLGAE 283

Query: 406 HL------VKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLK 567
           HL      + LDL  NKLR +P +   L +L+ LDL NN + +LP S   L  LK+L L+
Sbjct: 284 HLQHLQAILVLDLRGNKLRSVPEEMALLQSLERLDLSNNDISSLPCSLGNL-HLKFLALE 342

Query: 568 DNPLDPVLAKV 600
            NPL  +  ++
Sbjct: 343 GNPLRTIRREI 353


>ref|NP_997649.1| CCR4-NOT transcription complex subunit 6 [Mus musculus].
          Length = 552

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 45/125 (36%), Positives = 71/125 (56%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L +L+  T L LS N L+ +PS+   L +LV LDLS N+++ LPA+ G +V+L+ L L  
Sbjct: 47  LWSLTHLTALHLSDNSLSCIPSDIAKLHNLVYLDLSHNQIQSLPAELGNMVSLRELHLNY 106

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQAD 681
           N+L  LP    +L  L+ L LK NPL   +  +   CL+    ++  N +L ++ +V  +
Sbjct: 107 NQLRVLPFELGKLFQLQTLSLKGNPLTQDILNL---CLEPDGTRRLLNYLLDNL-SVSTE 162

Query: 682 QERER 696
           Q   R
Sbjct: 163 QPPPR 167



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 29/71 (40%), Positives = 41/71 (57%)
 Frame = +1

Query: 367 KLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKS 546
           K+ +L S    LTHL  L LS N L  +P+D  +L NL +LDL +N++ +LP     + S
Sbjct: 39  KVRSLSSSLWSLTHLTALHLSDNSLSCIPSDIAKLHNLVYLDLSHNQIQSLPAELGNMVS 98

Query: 547 LKWLDLKDNPL 579
           L+ L L  N L
Sbjct: 99  LRELHLNYNQL 109



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 31/78 (39%), Positives = 46/78 (58%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L LS + L+ +P  ++A L     LDLS N++ +LP+E   +  L +L L+ N+LR LP 
Sbjct: 56  LHLSDNSLSCIP-SDIAKLHNLVYLDLSHNQIQSLPAELGNMVSLRELHLNYNQLRVLPF 114

Query: 457 DFGRLVNLQHLDLLNNRL 510
           + G+L  LQ L L  N L
Sbjct: 115 ELGKLFQLQTLSLKGNPL 132


>ref|NP_073145.1| p53-induced protein with a death domain [Mus musculus].
          Length = 915

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 43/102 (42%), Positives = 62/102 (60%)
 Frame = +1

Query: 283 LSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADF 462
           LS + L+E+P + L AL   T L ++ N+L  LP     L+ L +LDLS+N L  +P++ 
Sbjct: 160 LSHNHLSELP-EALGALPALTFLTVTHNRLERLPLTLGSLSTLQRLDLSENLLDTIPSEI 218

Query: 463 GRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
           G L +L  L+L +NRL +LP S A L+SL+ L L  N L  V
Sbjct: 219 GNLRSLSELNLASNRLQSLPASLAGLRSLRLLVLHSNLLTSV 260



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 45/112 (40%), Positives = 57/112 (50%), Gaps = 2/112 (1%)
 Frame = +1

Query: 277 LDLSLSDLNEVP--VKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQL 450
           LDLS + L  +P  V EL  L     L LS N L+ LP     L  L  L ++ N+L +L
Sbjct: 135 LDLSFNRLETLPTCVPELHGLDA---LLLSHNHLSELPEALGALPALTFLTVTHNRLERL 191

Query: 451 PADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
           P   G L  LQ LDL  N L T+P     L+SL  L+L  N L  + A +AG
Sbjct: 192 PLTLGSLSTLQRLDLSENLLDTIPSEIGNLRSLSELNLASNRLQSLPASLAG 243



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 40/108 (37%), Positives = 62/108 (57%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L ++ + L  +P+  L +LS    LDLS N L T+PSE   L  L +L+L+ N+L+ LPA
Sbjct: 181 LTVTHNRLERLPLT-LGSLSTLQRLDLSENLLDTIPSEIGNLRSLSELNLASNRLQSLPA 239

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKV 600
               L +L+ L L +N L ++P     L  +  LDL+DN L  + A++
Sbjct: 240 SLAGLRSLRLLVLHSNLLTSVPTGLVHLPLITRLDLRDNRLRDLPAEL 287



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 47/121 (38%), Positives = 66/121 (54%)
 Frame = +1

Query: 238 KGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVK 417
           KGG  R  L G  L  +L+ L    + +LA L+    LDLS N+L TLP+    L  L  
Sbjct: 103 KGGQSRGAL-GACLHGTLTTL-PAGLSDLACLAH---LDLSFNRLETLPTCVPELHGLDA 157

Query: 418 LDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAK 597
           L LS N L +LP   G L  L  L + +NRL  LP++   L +L+ LDL +N LD + ++
Sbjct: 158 LLLSHNHLSELPEALGALPALTFLTVTHNRLERLPLTLGSLSTLQRLDLSENLLDTIPSE 217

Query: 598 V 600
           +
Sbjct: 218 I 218


>ref|NP_001153081.1| leucine-rich repeat-containing protein 57 isoform b [Mus musculus].
          Length = 264

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 52/153 (33%), Positives = 72/153 (47%), Gaps = 11/153 (7%)
 Frame = +1

Query: 154 RLLSLSPARRSPGAGTRSAGVTMTKAGS---KGGNLRD------KLDGN--ELDLSLSDL 300
           RL  LS   R   +  R+   T  K G    K   L +      KL  N   +DLS + +
Sbjct: 16  RLRELSRGARMGNSALRAHVETAQKTGVFQLKDRGLTEFPSELQKLTSNLRTIDLSNNKI 75

Query: 301 NEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNL 480
           + +P   +   +    L L+ NKLT LP E C L  L  L L+ N LR+LP+ FG+L  L
Sbjct: 76  DSLPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSAL 135

Query: 481 QHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
           + L L  N+L  LP     L+ L  +DL  N +
Sbjct: 136 KTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQI 168



 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 38/102 (37%), Positives = 56/102 (54%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L E+P      LS    L LS N+L  LP + C L HL  +DLSKN++R +P 
Sbjct: 115 LSLNNNHLRELP-STFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPD 173

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
             G L  ++ L+L  N++  L V  +    LK L L++N L+
Sbjct: 174 TVGELQAIE-LNLNQNQISQLSVKISCCPRLKVLRLEENCLE 214


>ref|NP_001153084.1| leucine-rich repeat-containing protein 57 isoform c [Mus musculus].
          Length = 239

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 38/101 (37%), Positives = 55/101 (54%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           +DLS + ++ +P   +   +    L L+ NKLT LP E C L  L  L L+ N LR+LP+
Sbjct: 43  IDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPS 102

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            FG+L  L+ L L  N+L  LP     L+ L  +DL  N +
Sbjct: 103 TFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQI 143



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 39/95 (41%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
 Frame = +1

Query: 298 LNEVPVKELAALSKATILDLSCNKLTTLPSEFCG-LTHLVKLDLSKNKLRQLPADFGRLV 474
           L E P +     S    +DLS NK+ +LP    G  T L  L L+ NKL  LP +   L 
Sbjct: 26  LTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLK 85

Query: 475 NLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            L+ L L NN L  LP +F QL +LK L L  N L
Sbjct: 86  KLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQL 120



 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 38/102 (37%), Positives = 56/102 (54%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L E+P      LS    L LS N+L  LP + C L HL  +DLSKN++R +P 
Sbjct: 90  LSLNNNHLRELP-STFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPD 148

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
             G L  ++ L+L  N++  L V  +    LK L L++N L+
Sbjct: 149 TVGELQAIE-LNLNQNQISQLSVKISCCPRLKVLRLEENCLE 189


>ref|NP_001153082.1| leucine-rich repeat-containing protein 57 isoform a [Mus musculus].
          Length = 281

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 38/101 (37%), Positives = 55/101 (54%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           +DLS + ++ +P   +   +    L L+ NKLT LP E C L  L  L L+ N LR+LP+
Sbjct: 85  IDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPS 144

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            FG+L  L+ L L  N+L  LP     L+ L  +DL  N +
Sbjct: 145 TFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQI 185



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 39/95 (41%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
 Frame = +1

Query: 298 LNEVPVKELAALSKATILDLSCNKLTTLPSEFCG-LTHLVKLDLSKNKLRQLPADFGRLV 474
           L E P +     S    +DLS NK+ +LP    G  T L  L L+ NKL  LP +   L 
Sbjct: 68  LTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLK 127

Query: 475 NLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            L+ L L NN L  LP +F QL +LK L L  N L
Sbjct: 128 KLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQL 162



 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 38/102 (37%), Positives = 56/102 (54%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L E+P      LS    L LS N+L  LP + C L HL  +DLSKN++R +P 
Sbjct: 132 LSLNNNHLRELP-STFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPD 190

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
             G L  ++ L+L  N++  L V  +    LK L L++N L+
Sbjct: 191 TVGELQAIE-LNLNQNQISQLSVKISCCPRLKVLRLEENCLE 231


>ref|NP_079933.2| leucine-rich repeat-containing protein 57 isoform c [Mus musculus].
          Length = 239

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 38/101 (37%), Positives = 55/101 (54%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           +DLS + ++ +P   +   +    L L+ NKLT LP E C L  L  L L+ N LR+LP+
Sbjct: 43  IDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPS 102

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            FG+L  L+ L L  N+L  LP     L+ L  +DL  N +
Sbjct: 103 TFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQI 143



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 39/95 (41%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
 Frame = +1

Query: 298 LNEVPVKELAALSKATILDLSCNKLTTLPSEFCG-LTHLVKLDLSKNKLRQLPADFGRLV 474
           L E P +     S    +DLS NK+ +LP    G  T L  L L+ NKL  LP +   L 
Sbjct: 26  LTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLK 85

Query: 475 NLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            L+ L L NN L  LP +F QL +LK L L  N L
Sbjct: 86  KLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQL 120



 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 38/102 (37%), Positives = 56/102 (54%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L E+P      LS    L LS N+L  LP + C L HL  +DLSKN++R +P 
Sbjct: 90  LSLNNNHLRELP-STFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPD 148

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
             G L  ++ L+L  N++  L V  +    LK L L++N L+
Sbjct: 149 TVGELQAIE-LNLNQNQISQLSVKISCCPRLKVLRLEENCLE 189


>ref|NP_001074827.1| leucine-rich repeat-containing protein 7 [Mus musculus].
          Length = 1542

 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 41/100 (41%), Positives = 59/100 (59%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           ELD+S + + E P + +      TI++ S N ++ LP  F  L +L +L L+   L  LP
Sbjct: 101 ELDISKNGVQEFP-ENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLP 159

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDN 573
           A+FGRLV L+ L+L  N L TLP S  +L  L+ LDL +N
Sbjct: 160 ANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNN 199



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 41/114 (35%), Positives = 61/114 (53%), Gaps = 4/114 (3%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAA----LSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLR 444
           L+L+   LN+  ++ L A    L K  IL+L  N L TLP     L  L +LDL  N+  
Sbjct: 143 LNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFS 202

Query: 445 QLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
           +LP    ++ NL+ L + NN L  LP S  +LK L +LD+  N ++ V   ++G
Sbjct: 203 ELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISG 256



 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 49/168 (29%), Positives = 75/168 (44%), Gaps = 12/168 (7%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           E D S ++L  +P   +  L     L +  N L  LP E     ++  + L  NKL  LP
Sbjct: 308 EFDCSCNELESLP-PTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLP 366

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAGDCLDEKQCK 633
            + G++  L+ L+L +NRL  LP SF +LK L  L L DN     L  +  +   E + +
Sbjct: 367 EEIGQMQRLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ-SKALIPLQTEAHPETKQR 425

Query: 634 QCANKVLQHM----KAVQADQ--------ERERQRRLEIDREAEKKWE 741
              N +        +  Q+D         E +RQ+R+ +  E E K E
Sbjct: 426 VLTNYMFPQQPRGDEDFQSDSDSFNPTLWEEQRQQRMTVAFEFEDKKE 473



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 33/107 (30%), Positives = 54/107 (50%)
 Frame = +1

Query: 259 KLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNK 438
           K+D N+L +  + +  + + E          D SCN+L +LP     L  L  L + +N 
Sbjct: 287 KVDDNQLTMLPNTIGNLSLLEE--------FDCSCNELESLPPTIGYLHSLRTLAVDENF 338

Query: 439 LRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
           L +LP + G   N+  + L +N+L  LP    Q++ L+ L+L DN L
Sbjct: 339 LPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRL 385


>ref|NP_001139520.1| leucine-rich repeat-containing protein 1 isoform 1 [Mus musculus].
          Length = 524

 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 47/123 (38%), Positives = 66/123 (53%)
 Frame = +1

Query: 244 GNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLD 423
           GNL++ L    LD+S + L  +P +E++ L+  T L +S N L T+P     L  L  L 
Sbjct: 217 GNLKNLLC---LDVSENRLERLP-EEISGLTSLTYLVISQNLLETIPEGIGKLKKLSILK 272

Query: 424 LSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
           L +N+L QLP   G   NL  L L  NRL+TLP S  +LK L  L+   N L  +  ++ 
Sbjct: 273 LDQNRLTQLPEAIGDCENLTELVLTENRLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIG 332

Query: 604 GDC 612
           G C
Sbjct: 333 GCC 335



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 44/133 (33%), Positives = 71/133 (53%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           ELDL  +++  +P + + AL     L L  N+L+ LP E   L +L+ LD+S+N+L +LP
Sbjct: 178 ELDLGNNEIYNLP-ESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLP 236

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAGDCLDEKQCK 633
            +   L +L +L +  N L T+P    +LK L  L L  N L   L +  GDC +  +  
Sbjct: 237 EEISGLTSLTYLVISQNLLETIPEGIGKLKKLSILKLDQNRLTQ-LPEAIGDCENLTELV 295

Query: 634 QCANKVLQHMKAV 672
              N++L   K++
Sbjct: 296 LTENRLLTLPKSI 308



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 41/106 (38%), Positives = 56/106 (52%)
 Frame = +1

Query: 262 LDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKL 441
           LDGN+L       +E+P +E+  L     LD+S N+L  LP E  GLT L  L +S+N L
Sbjct: 204 LDGNQL-------SELP-QEIGNLKNLLCLDVSENRLERLPEEISGLTSLTYLVISQNLL 255

Query: 442 RQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
             +P   G+L  L  L L  NRL  LP +    ++L  L L +N L
Sbjct: 256 ETIPEGIGKLKKLSILKLDQNRLTQLPEAIGDCENLTELVLTENRL 301



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 42/106 (39%), Positives = 57/106 (53%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           EL L+ + L  +P K +  L K + L+   NKL +LP E  G   L    +  N+L +LP
Sbjct: 293 ELVLTENRLLTLP-KSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTMFCIRDNRLTRLP 351

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVL 591
           A+  + V L  LD+  NRL  LP+S   LK LK L L DN   P+L
Sbjct: 352 AEVSQAVELHVLDVAGNRLHHLPLSLTTLK-LKALWLSDNQSQPLL 396



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 34/89 (38%), Positives = 46/89 (51%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L  L +   LDL  N++  LP     L HL  L L  N+L +LP + G L NL  LD+  
Sbjct: 170 LTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSE 229

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
           NRL  LP   + L SL +L +  N L+ +
Sbjct: 230 NRLERLPEEISGLTSLTYLVISQNLLETI 258



 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 37/109 (33%), Positives = 59/109 (54%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L +S + L  +P + +  L K +IL L  N+LT LP       +L +L L++N+L  LP 
Sbjct: 248 LVISQNLLETIP-EGIGKLKKLSILKLDQNRLTQLPEAIGDCENLTELVLTENRLLTLPK 306

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
             G+L  L +L+   N+LV+LP       SL    ++DN L  + A+V+
Sbjct: 307 SIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTMFCIRDNRLTRLPAEVS 355



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 40/121 (33%), Positives = 54/121 (44%), Gaps = 25/121 (20%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           ELD+S +D+ E+P + +A      + D S N LT LP  F  L +L  L ++   L+ LP
Sbjct: 86  ELDVSRNDIPEIP-ESIAFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLP 144

Query: 454 ADFGRLVNL-----------------------QHLDLLNNRLVTLPVSFAQLKSLK--WL 558
            + G L NL                       + LDL NN +  LP S   L  LK  WL
Sbjct: 145 ENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWL 204

Query: 559 D 561
           D
Sbjct: 205 D 205


  Database: RefSeq49_MP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 15,617,559
  Number of sequences in database:  30,036
  
Lambda     K      H
   0.315    0.132    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 30036
Number of Hits to DB: 29,422,691
Number of extensions: 659607
Number of successful extensions: 4494
Number of sequences better than 1.0e-05: 62
Number of HSP's gapped: 4169
Number of HSP's successfully gapped: 183
Length of query: 415
Length of database: 15,617,559
Length adjustment: 104
Effective length of query: 311
Effective length of database: 12,493,815
Effective search space: 3885576465
Effective search space used: 3885576465
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 35 (18.1 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-008867
         (1245 letters)

Database: RefSeq49_HP.fasta 
           32,964 sequences; 18,297,164 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_060979.2| leucine-rich repeat-containing protein 59 [Homo...   450   e-126
Alignment   gi|NP_056270.2| CCR4-NOT transcription complex subunit 6 [Homo ...    73   5e-13
Alignment   gi|NP_060238.3| leucine-rich repeat-containing protein 40 [Homo...    73   6e-13
Alignment   gi|NP_665894.2| p53-induced protein with a death domain isoform...    70   5e-12
Alignment   gi|NP_665893.2| p53-induced protein with a death domain isoform...    70   5e-12
Alignment   gi|NP_653172.2| CCR4-NOT transcription complex subunit 6-like [...    69   9e-12
Alignment   gi|NP_694992.2| leucine-rich repeat-containing protein 57 [Homo...    68   2e-11
Alignment   gi|NP_056171.2| protein scribble homolog isoform b [Homo sapien...    67   4e-11
Alignment   gi|NP_874365.2| protein scribble homolog isoform a [Homo sapien...    67   4e-11
Alignment   gi|NP_065845.1| leucine-rich repeat-containing protein 7 [Homo ...    66   6e-11

>ref|NP_060979.2| leucine-rich repeat-containing protein 59 [Homo sapiens].
          Length = 307

 Score =  450 bits (1158), Expect = e-126
 Identities = 237/305 (77%), Positives = 246/305 (80%), Gaps = 1/305 (0%)
 Frame = +1

Query: 220  MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCG 399
            MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAAL KATILDLSCNKLTTLPS+FCG
Sbjct: 1    MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCG 60

Query: 400  LTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            LTHLVKLDLSKNKL+QLPADFGRLVNLQHLDLLNN+LVTLPVSFAQLK+LKWLDLKDNPL
Sbjct: 61   LTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPL 120

Query: 580  DPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEIDREAEKKWEAKQXXX 759
            DPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLE++REAEKK EAKQ   
Sbjct: 121  DPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEVEREAEKKREAKQRAK 180

Query: 760  XXXXXXXXXXXXXXXXXXXXXXYDALKAAKREQEKKPKKETNQAXXXXXXXXXXXXXXXX 939
                                  YDALKAAKREQEKKPKKE NQA                
Sbjct: 181  EAQERELRKREKAEEKERRRKEYDALKAAKREQEKKPKKEANQAPKSKSGSRPRKPPPRK 240

Query: 940  XXXXWAVLXXXXXXXXC-VAGGLVACRVTELQQQPLCTSVNTIYDNAVRGLRSHDIVQWV 1116
                WAVL          VAGGLVACRVTELQQQPLCTSVNTIYDNAV+GLR H+I+QWV
Sbjct: 241  HTRSWAVLKLLLLLLLFGVAGGLVACRVTELQQQPLCTSVNTIYDNAVQGLRRHEILQWV 300

Query: 1117 LQTDS 1131
            LQTDS
Sbjct: 301  LQTDS 305


>ref|NP_056270.2| CCR4-NOT transcription complex subunit 6 [Homo sapiens].
          Length = 557

 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 41/86 (47%), Positives = 54/86 (62%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L +L+  T L LS N L+ +PS+   L +LV LDLS NK+R LPA+ G +V+L+ L L N
Sbjct: 47  LWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNN 106

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPL 579
           N L  LP    +L  L+ L LK NPL
Sbjct: 107 NLLRVLPFELGKLFQLQTLGLKGNPL 132



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 28/71 (39%), Positives = 43/71 (60%)
 Frame = +1

Query: 367 KLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKS 546
           K+ +L +    LTHL  L LS N L ++P+D  +L NL +LDL +N++ +LP     + S
Sbjct: 39  KVRSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVS 98

Query: 547 LKWLDLKDNPL 579
           L+ L L +N L
Sbjct: 99  LRELHLNNNLL 109



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 32/78 (41%), Positives = 45/78 (57%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L LS + L+ +P  ++A L     LDLS NK+ +LP+E   +  L +L L+ N LR LP 
Sbjct: 56  LHLSDNSLSRIP-SDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPF 114

Query: 457 DFGRLVNLQHLDLLNNRL 510
           + G+L  LQ L L  N L
Sbjct: 115 ELGKLFQLQTLGLKGNPL 132


>ref|NP_060238.3| leucine-rich repeat-containing protein 40 [Homo sapiens].
          Length = 602

 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 39/83 (46%), Positives = 55/83 (66%)
 Frame = +1

Query: 331 LSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRL 510
           LS    LDLS N LTT+P+ F  L+ LV+L+LS N+L+ LPA+  R+  L+HLD  +N L
Sbjct: 173 LSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLL 232

Query: 511 VTLPVSFAQLKSLKWLDLKDNPL 579
            T+P   A ++SL+ L L+ N L
Sbjct: 233 ETIPPELAGMESLELLYLRRNKL 255



 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 47/138 (34%), Positives = 71/138 (51%), Gaps = 23/138 (16%)
 Frame = +1

Query: 256 DKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKN 435
           ++ D  +L +S + L  +   +L  L   T+LD+  N+LT+LPS    L +L KL++S N
Sbjct: 80  EQTDLTKLIISNNKLQSL-TDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHN 138

Query: 436 KLRQLPAD-----------------------FGRLVNLQHLDLLNNRLVTLPVSFAQLKS 546
           KL+ LP +                       F +L NL+ LDL NN L T+P SF+ L S
Sbjct: 139 KLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSS 198

Query: 547 LKWLDLKDNPLDPVLAKV 600
           L  L+L  N L  + A++
Sbjct: 199 LVRLNLSSNELKSLPAEI 216



 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 41/119 (34%), Positives = 66/119 (55%)
 Frame = +1

Query: 250 LRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLS 429
           +R+  +  +L++S + L  +P +E+  L     L L  N+LT +   F  L++L  LDLS
Sbjct: 124 IRELENLQKLNVSHNKLKILP-EEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLS 182

Query: 430 KNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
            N L  +PA F  L +L  L+L +N L +LP    ++K LK LD   N L+ +  ++AG
Sbjct: 183 NNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAG 241



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 33/104 (31%), Positives = 54/104 (51%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           ++ S + L E+P + +      + +DLS NKL+ +  E C L  L  LDL  N L  LP 
Sbjct: 430 INFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPE 489

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPV 588
           +   LV LQ ++L  NR   LP    ++ +L+ + + +N +  V
Sbjct: 490 EMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSV 533



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 39/126 (30%), Positives = 56/126 (44%), Gaps = 24/126 (19%)
 Frame = +1

Query: 271 NELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQL 450
           +++DLS + L+ + + EL  L K T LDL  N L +LP E   L  L  ++LS N+ + L
Sbjct: 452 SDVDLSFNKLSFISL-ELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKML 510

Query: 451 PADFGRLV------------------------NLQHLDLLNNRLVTLPVSFAQLKSLKWL 558
           P    R+                         NL  LDL NN L+ +P       +L+ L
Sbjct: 511 PEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTL 570

Query: 559 DLKDNP 576
            L  NP
Sbjct: 571 LLDGNP 576



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 37/105 (35%), Positives = 55/105 (52%), Gaps = 1/105 (0%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L+LS ++L  +P  E+  + +   LD + N L T+P E  G+  L  L L +NKLR LP 
Sbjct: 202 LNLSSNELKSLPA-EINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLP- 259

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVS-FAQLKSLKWLDLKDNPLDPV 588
           +F     L+ L +  N++  L       L S+  LDL+DN L  V
Sbjct: 260 EFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSV 304


>ref|NP_665894.2| p53-induced protein with a death domain isoform 3 [Homo sapiens].
          Length = 893

 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 47/107 (43%), Positives = 65/107 (60%)
 Frame = +1

Query: 283 LSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADF 462
           LS + L+E+P + L AL   T L ++ N+L TLP     L+ L +LDLS+N L  LP + 
Sbjct: 155 LSHNCLSELP-EALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEI 213

Query: 463 GRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
           G L +L  L+L +NRL +LP S A L+SL+ L L  N L  V A +A
Sbjct: 214 GGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLA 260



 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 40/86 (46%), Positives = 53/86 (61%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L ALS    LDLS N L TLP E  GL  L++L+L+ N+L+ LPA    L +L+ L L +
Sbjct: 190 LGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHS 249

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPL 579
           N L ++P   A+L  L  LDL+DN L
Sbjct: 250 NLLASVPADLARLPLLTRLDLRDNQL 275



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 48/123 (39%), Positives = 64/123 (52%)
 Frame = +1

Query: 238 KGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVK 417
           KGG  RD L G  L  +L++L       L+ L+    LDLS N L TLP+    +  L  
Sbjct: 98  KGGQRRDTL-GACLRGALTNLPA----GLSGLAHLAHLDLSFNSLETLPACVLQMRGLGA 152

Query: 418 LDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAK 597
           L LS N L +LP   G L  L  L + +NRL TLP +   L +L+ LDL  N LD +  +
Sbjct: 153 LLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPE 212

Query: 598 VAG 606
           + G
Sbjct: 213 IGG 215



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 43/110 (39%), Positives = 54/110 (49%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           LDLS + L  +P   L       +L LS N L+ LP     L  L  L ++ N+L+ LP 
Sbjct: 130 LDLSFNSLETLPACVLQMRGLGALL-LSHNCLSELPEALGALPALTFLTVTHNRLQTLPP 188

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
             G L  LQ LDL  N L TLP     L SL  L+L  N L  + A +AG
Sbjct: 189 ALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAG 238



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 39/101 (38%), Positives = 55/101 (54%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           LDLS + L+ +P  E+  L     L+L+ N+L +LP+   GL  L  L L  N L  +PA
Sbjct: 199 LDLSQNLLDTLP-PEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPA 257

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
           D  RL  L  LDL +N+L  LP    +L    ++ L+ NPL
Sbjct: 258 DLARLPLLTRLDLRDNQLRDLP---PELLDAPFVRLQGNPL 295


>ref|NP_665893.2| p53-induced protein with a death domain isoform 1 [Homo sapiens].
          Length = 910

 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 47/107 (43%), Positives = 65/107 (60%)
 Frame = +1

Query: 283 LSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADF 462
           LS + L+E+P + L AL   T L ++ N+L TLP     L+ L +LDLS+N L  LP + 
Sbjct: 155 LSHNCLSELP-EALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEI 213

Query: 463 GRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
           G L +L  L+L +NRL +LP S A L+SL+ L L  N L  V A +A
Sbjct: 214 GGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLA 260



 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 40/86 (46%), Positives = 53/86 (61%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L ALS    LDLS N L TLP E  GL  L++L+L+ N+L+ LPA    L +L+ L L +
Sbjct: 190 LGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHS 249

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPL 579
           N L ++P   A+L  L  LDL+DN L
Sbjct: 250 NLLASVPADLARLPLLTRLDLRDNQL 275



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 48/123 (39%), Positives = 64/123 (52%)
 Frame = +1

Query: 238 KGGNLRDKLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVK 417
           KGG  RD L G  L  +L++L       L+ L+    LDLS N L TLP+    +  L  
Sbjct: 98  KGGQRRDTL-GACLRGALTNLPA----GLSGLAHLAHLDLSFNSLETLPACVLQMRGLGA 152

Query: 418 LDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAK 597
           L LS N L +LP   G L  L  L + +NRL TLP +   L +L+ LDL  N LD +  +
Sbjct: 153 LLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPE 212

Query: 598 VAG 606
           + G
Sbjct: 213 IGG 215



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 43/110 (39%), Positives = 54/110 (49%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           LDLS + L  +P   L       +L LS N L+ LP     L  L  L ++ N+L+ LP 
Sbjct: 130 LDLSFNSLETLPACVLQMRGLGALL-LSHNCLSELPEALGALPALTFLTVTHNRLQTLPP 188

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
             G L  LQ LDL  N L TLP     L SL  L+L  N L  + A +AG
Sbjct: 189 ALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAG 238



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 39/101 (38%), Positives = 55/101 (54%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           LDLS + L+ +P  E+  L     L+L+ N+L +LP+   GL  L  L L  N L  +PA
Sbjct: 199 LDLSQNLLDTLP-PEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPA 257

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
           D  RL  L  LDL +N+L  LP    +L    ++ L+ NPL
Sbjct: 258 DLARLPLLTRLDLRDNQLRDLP---PELLDAPFVRLQGNPL 295


>ref|NP_653172.2| CCR4-NOT transcription complex subunit 6-like [Homo sapiens].
          Length = 555

 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 40/86 (46%), Positives = 53/86 (61%)
 Frame = +1

Query: 322 LAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLN 501
           L +L+  T L L+ N L+ +P +   L +LV LDLS NKLR LPA+ G +V+L+ L L N
Sbjct: 52  LWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNN 111

Query: 502 NRLVTLPVSFAQLKSLKWLDLKDNPL 579
           N L  LP    +L  L+ L LK NPL
Sbjct: 112 NLLRVLPYELGRLFQLQTLGLKGNPL 137



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 33/78 (42%), Positives = 45/78 (57%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L+ +P  ++A L     LDLS NKL +LP+E   +  L +L L+ N LR LP 
Sbjct: 61  LHLNDNYLSRIP-PDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNNNLLRVLPY 119

Query: 457 DFGRLVNLQHLDLLNNRL 510
           + GRL  LQ L L  N L
Sbjct: 120 ELGRLFQLQTLGLKGNPL 137



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 27/71 (38%), Positives = 42/71 (59%)
 Frame = +1

Query: 367 KLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKS 546
           ++ +L +    LTHL  L L+ N L ++P D  +L NL +LDL +N+L +LP     + S
Sbjct: 44  RVRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVS 103

Query: 547 LKWLDLKDNPL 579
           L+ L L +N L
Sbjct: 104 LRELLLNNNLL 114


>ref|NP_694992.2| leucine-rich repeat-containing protein 57 [Homo sapiens].
          Length = 239

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 38/101 (37%), Positives = 54/101 (53%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           +DLS + +  +P   +   +    L L+ NKLT LP E C L  L  L L+ N LR+LP+
Sbjct: 43  IDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPS 102

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            FG+L  L+ L L  N+L  LP     L+ L  +DL  N +
Sbjct: 103 TFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQI 143



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 39/95 (41%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
 Frame = +1

Query: 298 LNEVPVKELAALSKATILDLSCNKLTTLPSEFCG-LTHLVKLDLSKNKLRQLPADFGRLV 474
           L E P       S    +DLS NK+ +LP    G  T L  L L+ NKL  LP +   L 
Sbjct: 26  LTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDEICNLK 85

Query: 475 NLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
            L+ L L NN L  LP +F QL +LK L L  N L
Sbjct: 86  KLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQL 120



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 36/109 (33%), Positives = 58/109 (53%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPA 456
           L L+ + L  +P  E+  L K   L L+ N L  LPS F  L+ L  L LS N+L  LP 
Sbjct: 67  LSLNNNKLTVLP-DEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPP 125

Query: 457 DFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVA 603
               L +L  +DL  N++ ++P S  +L+ ++ L+L  N +  +  K++
Sbjct: 126 QLCSLRHLDVMDLSKNQIRSIPDSVGELQVIE-LNLNQNQISQISVKIS 173


>ref|NP_056171.2| protein scribble homolog isoform b [Homo sapiens].
          Length = 1630

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 48/113 (42%), Positives = 60/113 (53%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           +LDL  +DL  +P   L AL     L L  N+L+ LP E   L  LV LD+S+N+L +LP
Sbjct: 178 QLDLGGNDLEVLP-DTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELP 236

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAGDC 612
           A+ G LV L  L L  N L  LP    QLK L  L +  N L  V  +  GDC
Sbjct: 237 AELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEV-TEAIGDC 288



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 41/103 (39%), Positives = 55/103 (53%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           ELD+S +D+ E+P + +       I D S N L+ LP  F  L  L  L L+   L+ LP
Sbjct: 86  ELDVSRNDIPEIP-ESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALP 144

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
            D G L NL  L+L  N L +LP S + L  L+ LDL  N L+
Sbjct: 145 GDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLE 187



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 38/107 (35%), Positives = 55/107 (51%), Gaps = 4/107 (3%)
 Frame = +1

Query: 298 LNEVPVKELAA----LSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFG 465
           LN+V ++ L      L+    L+L  N L +LP+    L  L +LDL  N L  LP   G
Sbjct: 135 LNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLG 194

Query: 466 RLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
            L NL+ L L  N+L  LP     L+ L  LD+ +N L+ + A++ G
Sbjct: 195 ALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGG 241



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 39/102 (38%), Positives = 55/102 (53%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           EL L  + L+ +P  EL  L +   LD+S N+L  LP+E  GL  L  L LS+N LR+LP
Sbjct: 201 ELWLDRNQLSALP-PELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLP 259

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
              G+L  L  L +  NRL  +  +    ++L  L L +N L
Sbjct: 260 DGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLL 301



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 39/107 (36%), Positives = 55/107 (51%)
 Frame = +1

Query: 271 NELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQL 450
           +EL L+ + L  +P + L  L+K T L++  N L  LP E  G   L  L L  N+L  L
Sbjct: 292 SELILTENLLMALP-RSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVL 350

Query: 451 PADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVL 591
           P +      L  LD+  NRL +LP +   L +LK L L +N   P+L
Sbjct: 351 PPELAHTTELHVLDVAGNRLQSLPFALTHL-NLKALWLAENQAQPML 396


>ref|NP_874365.2| protein scribble homolog isoform a [Homo sapiens].
          Length = 1655

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 48/113 (42%), Positives = 60/113 (53%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           +LDL  +DL  +P   L AL     L L  N+L+ LP E   L  LV LD+S+N+L +LP
Sbjct: 178 QLDLGGNDLEVLP-DTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELP 236

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAGDC 612
           A+ G LV L  L L  N L  LP    QLK L  L +  N L  V  +  GDC
Sbjct: 237 AELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEV-TEAIGDC 288



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 41/103 (39%), Positives = 55/103 (53%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           ELD+S +D+ E+P + +       I D S N L+ LP  F  L  L  L L+   L+ LP
Sbjct: 86  ELDVSRNDIPEIP-ESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALP 144

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
            D G L NL  L+L  N L +LP S + L  L+ LDL  N L+
Sbjct: 145 GDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLE 187



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 38/107 (35%), Positives = 55/107 (51%), Gaps = 4/107 (3%)
 Frame = +1

Query: 298 LNEVPVKELAA----LSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLPADFG 465
           LN+V ++ L      L+    L+L  N L +LP+    L  L +LDL  N L  LP   G
Sbjct: 135 LNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLG 194

Query: 466 RLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
            L NL+ L L  N+L  LP     L+ L  LD+ +N L+ + A++ G
Sbjct: 195 ALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGG 241



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 39/102 (38%), Positives = 55/102 (53%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           EL L  + L+ +P  EL  L +   LD+S N+L  LP+E  GL  L  L LS+N LR+LP
Sbjct: 201 ELWLDRNQLSALP-PELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLP 259

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
              G+L  L  L +  NRL  +  +    ++L  L L +N L
Sbjct: 260 DGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLL 301



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 39/107 (36%), Positives = 55/107 (51%)
 Frame = +1

Query: 271 NELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQL 450
           +EL L+ + L  +P + L  L+K T L++  N L  LP E  G   L  L L  N+L  L
Sbjct: 292 SELILTENLLMALP-RSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVL 350

Query: 451 PADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVL 591
           P +      L  LD+  NRL +LP +   L +LK L L +N   P+L
Sbjct: 351 PPELAHTTELHVLDVAGNRLQSLPFALTHL-NLKALWLAENQAQPML 396


>ref|NP_065845.1| leucine-rich repeat-containing protein 7 [Homo sapiens].
          Length = 1537

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 41/100 (41%), Positives = 59/100 (59%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           ELD+S + + E P + +      TI++ S N ++ LP  F  L +L +L L+   L  LP
Sbjct: 96  ELDISKNGVQEFP-ENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLP 154

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDN 573
           A+FGRLV L+ L+L  N L TLP S  +L  L+ LDL +N
Sbjct: 155 ANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNN 194



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 41/114 (35%), Positives = 61/114 (53%), Gaps = 4/114 (3%)
 Frame = +1

Query: 277 LDLSLSDLNEVPVKELAA----LSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLR 444
           L+L+   LN+  ++ L A    L K  IL+L  N L TLP     L  L +LDL  N+  
Sbjct: 138 LNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFG 197

Query: 445 QLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAG 606
           +LP    ++ NL+ L + NN L  LP S  +LK L +LD+  N ++ V   ++G
Sbjct: 198 ELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISG 251



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 49/168 (29%), Positives = 75/168 (44%), Gaps = 12/168 (7%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           E D S ++L  +P   +  L     L +  N L  LP E     ++  + L  NKL  LP
Sbjct: 303 EFDCSCNELESLP-STIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLP 361

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLDPVLAKVAGDCLDEKQCK 633
            + G++  L+ L+L +NRL  LP SF +LK L  L L DN     L  +  +   E + +
Sbjct: 362 EEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ-SKALIPLQTEAHPETKQR 420

Query: 634 QCANKVLQHM----KAVQADQ--------ERERQRRLEIDREAEKKWE 741
              N +        +  Q+D         E +RQ+R+ +  E E K E
Sbjct: 421 VLTNYMFPQQPRGDEDFQSDSDSFNPTLWEEQRQQRMTVAFEFEDKKE 468



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 34/107 (31%), Positives = 55/107 (51%)
 Frame = +1

Query: 259 KLDGNELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNK 438
           K+D N+L +  + +  + + E          D SCN+L +LPS    L  L  L + +N 
Sbjct: 282 KVDDNQLTMLPNTIGNLSLLEE--------FDCSCNELESLPSTIGYLHSLRTLAVDENF 333

Query: 439 LRQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPL 579
           L +LP + G   N+  + L +N+L  LP    Q++ L+ L+L DN L
Sbjct: 334 LPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRL 380



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 34/103 (33%), Positives = 54/103 (52%)
 Frame = +1

Query: 274 ELDLSLSDLNEVPVKELAALSKATILDLSCNKLTTLPSEFCGLTHLVKLDLSKNKLRQLP 453
           +L LS + L ++P   +  L K T L +  N+LT LP+    L+ L + D S N+L  LP
Sbjct: 257 DLLLSSNMLQQLP-DSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLP 315

Query: 454 ADFGRLVNLQHLDLLNNRLVTLPVSFAQLKSLKWLDLKDNPLD 582
           +  G L +L+ L +  N L  LP      K++  + L+ N L+
Sbjct: 316 STIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358


  Database: RefSeq49_HP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,297,164
  Number of sequences in database:  32,964
  
Lambda     K      H
   0.315    0.132    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 32964
Number of Hits to DB: 34,907,632
Number of extensions: 794757
Number of successful extensions: 5566
Number of sequences better than 1.0e-05: 77
Number of HSP's gapped: 5163
Number of HSP's successfully gapped: 196
Length of query: 415
Length of database: 18,297,164
Length adjustment: 105
Effective length of query: 310
Effective length of database: 14,835,944
Effective search space: 4599142640
Effective search space used: 4599142640
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 35 (18.1 bits)

BLASTN 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 20110601C-008867
         (1245 letters)

Database: Sscrofa_10.2.fasta 
           4582 sequences; 2,808,509,378 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Sscrofa_Chr12                                                         525   e-146

>Sscrofa_Chr12 
||          Length = 63588571

 Score =  525 bits (265), Expect = e-146
 Identities = 323/350 (92%)
 Strand = Plus / Plus

                                                                            
Query: 896      aatcaaagtccggctctcgccctcgtaagccgccaccccggaaacacactcggtcctggg 955
                |||||||||||||||||||||| |||||||||||||||||||||||||||||||||||||
Sbjct: 26601732 aatcaaagtccggctctcgcccccgtaagccgccaccccggaaacacactcggtcctggg 26601791

                                                                            
Query: 956      ctgtgctgaannnnnnnnnnnnnnnnnnnnnntgtgtggctggcgggctggttgcttgtc 1015
                ||||||||||                      ||||||||||||||||||||||||||||
Sbjct: 26601792 ctgtgctgaagctgctgctgctgctgctgctgtgtgtggctggcgggctggttgcttgtc 26601851

                                                                            
Query: 1016     gggtgacagagctgcagcagcagcccctgtgcaccagcgtgaacaccatctacgacaacg 1075
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26601852 gggtgacagagctgcagcagcagcccctgtgcaccagcgtgaacaccatctacgacaacg 26601911

                                                                            
Query: 1076     cggtccggggcctgcgcagccacgacatcgtccaatgggtcctgcagaccgattctcagc 1135
                | |||||||||||||||||||||||||||||||| |||||||||||||||||||||||||
Sbjct: 26601912 cagtccggggcctgcgcagccacgacatcgtccagtgggtcctgcagaccgattctcagc 26601971

                                                                            
Query: 1136     agtgagcttgtcctncacaactgctgcctcccagccttggagcttggattcctatggaat 1195
                ||||||||||||||  ||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26601972 agtgagcttgtcctcaacaactgctgcctcccagccttggagcttggattcctatggaat 26602031

                                                                  
Query: 1196     tgggttctgctggacacaacctctttttagtgtcagacctacctgccatc 1245
                ||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26602032 tgggttctgctggacacaacctctttttagtgtcagacctacctgccatc 26602081



 Score =  480 bits (242), Expect = e-133
 Identities = 242/242 (100%)
 Strand = Plus / Plus

                                                                            
Query: 84       tgatctcgcacctgcggcggcgggggacgtaggctttgtcggttgagtgcgcgtcccctc 143
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26587731 tgatctcgcacctgcggcggcgggggacgtaggctttgtcggttgagtgcgcgtcccctc 26587790

                                                                            
Query: 144      agtccacgagcggcttctcagcctttctcctgcccgtcggagccccggggccgggacccg 203
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26587791 agtccacgagcggcttctcagcctttctcctgcccgtcggagccccggggccgggacccg 26587850

                                                                            
Query: 204      ttcagccggcgtcaccatgaccaaggccggtagcaagggcgggaacctccgcgacaagct 263
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26587851 ttcagccggcgtcaccatgaccaaggccggtagcaagggcgggaacctccgcgacaagct 26587910

                                                                            
Query: 264      tgacggcaacgagctggacctgagcctcagcgacctgaatgaggtccctgtcaaggagct 323
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26587911 tgacggcaacgagctggacctgagcctcagcgacctgaatgaggtccctgtcaaggagct 26587970

                  
Query: 324      gg 325
                ||
Sbjct: 26587971 gg 26587972



 Score =  480 bits (242), Expect = e-133
 Identities = 242/242 (100%)
 Strand = Plus / Minus

                                                                            
Query: 84       tgatctcgcacctgcggcggcgggggacgtaggctttgtcggttgagtgcgcgtcccctc 143
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26782945 tgatctcgcacctgcggcggcgggggacgtaggctttgtcggttgagtgcgcgtcccctc 26782886

                                                                            
Query: 144      agtccacgagcggcttctcagcctttctcctgcccgtcggagccccggggccgggacccg 203
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26782885 agtccacgagcggcttctcagcctttctcctgcccgtcggagccccggggccgggacccg 26782826

                                                                            
Query: 204      ttcagccggcgtcaccatgaccaaggccggtagcaagggcgggaacctccgcgacaagct 263
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26782825 ttcagccggcgtcaccatgaccaaggccggtagcaagggcgggaacctccgcgacaagct 26782766

                                                                            
Query: 264      tgacggcaacgagctggacctgagcctcagcgacctgaatgaggtccctgtcaaggagct 323
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26782765 tgacggcaacgagctggacctgagcctcagcgacctgaatgaggtccctgtcaaggagct 26782706

                  
Query: 324      gg 325
                ||
Sbjct: 26782705 gg 26782704



 Score =  349 bits (176), Expect = 2e-93
 Identities = 176/176 (100%)
 Strand = Plus / Plus

                                                                            
Query: 720      agaggctgagaagaagtgggaagccaagcagcgagctaaggaggctcaggagcgggaact 779
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26598930 agaggctgagaagaagtgggaagccaagcagcgagctaaggaggctcaggagcgggaact 26598989

                                                                            
Query: 780      gcggaagcgggagaaggcggaagagaaggagcgccggagaaaggagtatgacgccctcaa 839
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26598990 gcggaagcgggagaaggcggaagagaaggagcgccggagaaaggagtatgacgccctcaa 26599049

                                                                        
Query: 840      agcggccaagcgagagcaggagaagaaaccgaagaaggaaacaaatcaggccccga 895
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26599050 agcggccaagcgagagcaggagaagaaaccgaagaaggaaacaaatcaggccccga 26599105



 Score =  349 bits (176), Expect = 2e-93
 Identities = 176/176 (100%)
 Strand = Plus / Minus

                                                                            
Query: 720      agaggctgagaagaagtgggaagccaagcagcgagctaaggaggctcaggagcgggaact 779
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26771743 agaggctgagaagaagtgggaagccaagcagcgagctaaggaggctcaggagcgggaact 26771684

                                                                            
Query: 780      gcggaagcgggagaaggcggaagagaaggagcgccggagaaaggagtatgacgccctcaa 839
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26771683 gcggaagcgggagaaggcggaagagaaggagcgccggagaaaggagtatgacgccctcaa 26771624

                                                                        
Query: 840      agcggccaagcgagagcaggagaagaaaccgaagaaggaaacaaatcaggccccga 895
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26771623 agcggccaagcgagagcaggagaagaaaccgaagaaggaaacaaatcaggccccga 26771568



 Score =  317 bits (160), Expect = 8e-84
 Identities = 160/160 (100%)
 Strand = Plus / Minus

                                                                            
Query: 384      gtcggagttctgtggcctcacacacctggtgaagctggacctgagtaagaacaagctgcg 443
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26779306 gtcggagttctgtggcctcacacacctggtgaagctggacctgagtaagaacaagctgcg 26779247

                                                                            
Query: 444      gcagctgccggcggactttggccgcctggtcaacctccagcacctggacctcctcaacaa 503
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26779246 gcagctgccggcggactttggccgcctggtcaacctccagcacctggacctcctcaacaa 26779187

                                                        
Query: 504      caggctggtcaccctgcctgtcagctttgctcagctcaag 543
                ||||||||||||||||||||||||||||||||||||||||
Sbjct: 26779186 caggctggtcaccctgcctgtcagctttgctcagctcaag 26779147



 Score =  301 bits (152), Expect = 5e-79
 Identities = 159/160 (99%), Gaps = 1/160 (0%)
 Strand = Plus / Plus

                                                                            
Query: 384      gtcggagttctgtggcctcacacacctggtgaagctggacctgagtaagaacaagctgcg 443
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26591370 gtcggagttctgtggcctcacacacctggtgaagctggacctgagtaagaacaagctgcg 26591429

                                                                            
Query: 444      gcagctgccggcggactttggccgcctggtcaacctccagcacctggacctcctcaacaa 503
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||| ||||
Sbjct: 26591430 gcagctgccggcggactttggccgcctggtcaacctccagcacctggacctcctc-acaa 26591488

                                                        
Query: 504      caggctggtcaccctgcctgtcagctttgctcagctcaag 543
                ||||||||||||||||||||||||||||||||||||||||
Sbjct: 26591489 caggctggtcaccctgcctgtcagctttgctcagctcaag 26591528



 Score =  216 bits (109), Expect = 2e-53
 Identities = 109/109 (100%)
 Strand = Plus / Plus

                                                                            
Query: 542      agagcctcaagtggctggatctgaaggataaccccctggatcccgtcctggccaaggtgg 601
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26591740 agagcctcaagtggctggatctgaaggataaccccctggatcccgtcctggccaaggtgg 26591799

                                                                 
Query: 602      caggggattgcctggatgagaagcagtgcaagcagtgcgccaacaaggt 650
                |||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26591800 caggggattgcctggatgagaagcagtgcaagcagtgcgccaacaaggt 26591848



 Score =  216 bits (109), Expect = 2e-53
 Identities = 109/109 (100%)
 Strand = Plus / Minus

                                                                            
Query: 542      agagcctcaagtggctggatctgaaggataaccccctggatcccgtcctggccaaggtgg 601
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26778933 agagcctcaagtggctggatctgaaggataaccccctggatcccgtcctggccaaggtgg 26778874

                                                                 
Query: 602      caggggattgcctggatgagaagcagtgcaagcagtgcgccaacaaggt 650
                |||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26778873 caggggattgcctggatgagaagcagtgcaagcagtgcgccaacaaggt 26778825



 Score =  149 bits (75), Expect = 4e-33
 Identities = 75/75 (100%)
 Strand = Plus / Plus

                                                                            
Query: 647      aggtgctgcagcacatgaaggctgtgcaggcggatcaggagcgagagaggcagcggcggc 706
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26596238 aggtgctgcagcacatgaaggctgtgcaggcggatcaggagcgagagaggcagcggcggc 26596297

                               
Query: 707      tggaaatagacagag 721
                |||||||||||||||
Sbjct: 26596298 tggaaatagacagag 26596312



 Score =  149 bits (75), Expect = 4e-33
 Identities = 75/75 (100%)
 Strand = Plus / Minus

                                                                            
Query: 647      aggtgctgcagcacatgaaggctgtgcaggcggatcaggagcgagagaggcagcggcggc 706
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26774435 aggtgctgcagcacatgaaggctgtgcaggcggatcaggagcgagagaggcagcggcggc 26774376

                               
Query: 707      tggaaatagacagag 721
                |||||||||||||||
Sbjct: 26774375 tggaaatagacagag 26774361



 Score =  121 bits (61), Expect = 1e-24
 Identities = 61/61 (100%)
 Strand = Plus / Plus

                                                                            
Query: 324      ggctgccctctccaaggccaccatactggatctgtcctgcaataaactgactactctacc 383
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26589735 ggctgccctctccaaggccaccatactggatctgtcctgcaataaactgactactctacc 26589794

                 
Query: 384      g 384
                |
Sbjct: 26589795 g 26589795



 Score =  121 bits (61), Expect = 1e-24
 Identities = 61/61 (100%)
 Strand = Plus / Minus

                                                                            
Query: 324      ggctgccctctccaaggccaccatactggatctgtcctgcaataaactgactactctacc 383
                ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 26780941 ggctgccctctccaaggccaccatactggatctgtcctgcaataaactgactactctacc 26780882

                 
Query: 384      g 384
                |
Sbjct: 26780881 g 26780881


  Database: Sscrofa_10.2.fasta
    Posted date:  Nov 16, 2011 10:34 AM
  Number of letters in database: 2,808,509,378
  Number of sequences in database:  4582
  
Lambda     K      H
    1.37    0.711     1.31 

Gapped
Lambda     K      H
    1.37    0.711     1.31 


Matrix: blastn matrix:1 -3
Gap Penalties: Existence: 5, Extension: 2
Number of Sequences: 4582
Number of Hits to DB: 28,077,822
Number of extensions: 195
Number of successful extensions: 195
Number of sequences better than 1.0e-05: 1
Number of HSP's gapped: 194
Number of HSP's successfully gapped: 14
Length of query: 1245
Length of database: 2,808,509,378
Length adjustment: 21
Effective length of query: 1224
Effective length of database: 2,808,413,156
Effective search space: 3437497702944
Effective search space used: 3437497702944
X1: 11 (21.8 bits)
X2: 15 (29.7 bits)
X3: 50 (99.1 bits)
S1: 18 (36.2 bits)
S2: 30 (60.0 bits)