Animal-Genome cDNA AMP01_0016_F01

BLASTX 2.2.10 [Oct-19-2004]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AMP01_0016_F01
         (2121 letters)

Database: RefSeqBP 
           33,508 sequences; 16,112,626 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|XP_883516.1| PREDICTED: similar to Pleiotropic regulator 1 i...  1024   0.0  
Alignment   gi|XP_871567.1| PREDICTED: similar to Pleiotropic regulator 1 i...  1019   0.0  
Alignment   gi|XP_613526.2| PREDICTED: similar to Pleiotropic regulator 1 i...   993   0.0  
Alignment   gi|XP_883554.1| PREDICTED: similar to Pleiotropic regulator 1 i...   988   0.0  
Alignment   gi|XP_608583.2| PREDICTED: similar to CG7568-PA [Bos taurus]         131   2e-30
Alignment   gi|NP_777088.1| platelet-activating factor acetylhydrolase, iso...   128   2e-29
Alignment   gi|XP_883815.1| PREDICTED: similar to F-box protein FBW7 isofor...   125   1e-28
Alignment   gi|XP_883785.1| PREDICTED: similar to F-box protein FBW7 isofor...   125   1e-28
Alignment   gi|XP_883749.1| PREDICTED: similar to F-box protein FBW7 isofor...   125   1e-28
Alignment   gi|XP_613742.2| PREDICTED: similar to F-box protein FBW7 isofor...   125   1e-28

>ref|XP_883516.1| PREDICTED: similar to Pleiotropic regulator 1 isoform 4 [Bos taurus]
          Length = 513

 Score = 1024 bits (2647), Expect = 0.0
 Identities = 497/513 (96%), Positives = 502/513 (97%)
 Frame = +1

Query: 94   MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT 273
            MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
Sbjct: 1    MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT 60

Query: 274  SKENLKEKGPQNASDSYGHKQYPANQGQEVEYLVTGTHPYPPGPGVALTPDTKIQRMPSE 453
            SKENLKEK PQNASDSYGHKQYPANQGQEVEYLVTGTHPYPPGPGVALT DTKIQRMPSE
Sbjct: 61   SKENLKEKVPQNASDSYGHKQYPANQGQEVEYLVTGTHPYPPGPGVALTADTKIQRMPSE 120

Query: 454  SAAQSLAVALPTSQARVDANRSAPAAGEYRHPGASDRSQSAGAVVVDGGNAKNSALMAKK 633
            SAAQSLAVALP SQAR DANR  PA GEYRHPGA DR+Q AGAVV++G NAKNSALMAKK
Sbjct: 121  SAAQSLAVALPASQARADANRPVPAGGEYRHPGAPDRAQPAGAVVMEGSNAKNSALMAKK 180

Query: 634  APTMPKPQWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLS 813
            APTMPKPQWHPPWKLYRVISGHLGWVRCIAV+PGNQ FVTGSADRTIKIWDLASGKLKLS
Sbjct: 181  APTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLS 240

Query: 814  LTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTID 993
            LTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTID
Sbjct: 241  LTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTID 300

Query: 994  VLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVA 1173
            VLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVA
Sbjct: 301  VLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVA 360

Query: 1174 GKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTV 1353
            GKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTV
Sbjct: 361  GKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTV 420

Query: 1354 NSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAE 1533
            NSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAE
Sbjct: 421  NSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAE 480

Query: 1534 ADKTIKVYREDDTATEETHPVSWKPEIIKRKRF 1632
            ADKTIKVY+EDDTATEETHPVSWKPEIIKRKRF
Sbjct: 481  ADKTIKVYKEDDTATEETHPVSWKPEIIKRKRF 513


>ref|XP_871567.1| PREDICTED: similar to Pleiotropic regulator 1 isoform 3 [Bos taurus]
          Length = 515

 Score = 1019 bits (2634), Expect = 0.0
 Identities = 497/515 (96%), Positives = 502/515 (97%), Gaps = 2/515 (0%)
 Frame = +1

Query: 94   MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT 273
            MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
Sbjct: 1    MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT 60

Query: 274  SKENLKEKGPQNASDSYGHKQYPANQGQEVEYLVTGTHPYPPGPGVALTPDTKIQRMPSE 453
            SKENLKEK PQNASDSYGHKQYPANQGQEVEYLVTGTHPYPPGPGVALT DTKIQRMPSE
Sbjct: 61   SKENLKEKVPQNASDSYGHKQYPANQGQEVEYLVTGTHPYPPGPGVALTADTKIQRMPSE 120

Query: 454  SAAQSLAVALPTSQARVDANRSAPAAGEYRHPGASDRSQSAGA--VVVDGGNAKNSALMA 627
            SAAQSLAVALP SQAR DANR  PA GEYRHPGA DR+Q AGA  VV++G NAKNSALMA
Sbjct: 121  SAAQSLAVALPASQARADANRPVPAGGEYRHPGAPDRAQPAGATSVVMEGSNAKNSALMA 180

Query: 628  KKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLK 807
            KKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV+PGNQ FVTGSADRTIKIWDLASGKLK
Sbjct: 181  KKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLK 240

Query: 808  LSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPT 987
            LSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPT
Sbjct: 241  LSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPT 300

Query: 988  IDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 1167
            IDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL
Sbjct: 301  IDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 360

Query: 1168 VAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTL 1347
            VAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTL
Sbjct: 361  VAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTL 420

Query: 1348 TVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLT 1527
            TVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLT
Sbjct: 421  TVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLT 480

Query: 1528 AEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF 1632
            AEADKTIKVY+EDDTATEETHPVSWKPEIIKRKRF
Sbjct: 481  AEADKTIKVYKEDDTATEETHPVSWKPEIIKRKRF 515


>ref|XP_613526.2| PREDICTED: similar to Pleiotropic regulator 1 isoform 2 [Bos taurus]
          Length = 504

 Score =  993 bits (2567), Expect = 0.0
 Identities = 488/513 (95%), Positives = 493/513 (96%)
 Frame = +1

Query: 94   MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT 273
            MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
Sbjct: 1    MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT 60

Query: 274  SKENLKEKGPQNASDSYGHKQYPANQGQEVEYLVTGTHPYPPGPGVALTPDTKIQRMPSE 453
            SKENLKEK PQNASDSYGHKQYPANQGQEVEYLVTG         VALT DTKIQRMPSE
Sbjct: 61   SKENLKEKVPQNASDSYGHKQYPANQGQEVEYLVTG---------VALTADTKIQRMPSE 111

Query: 454  SAAQSLAVALPTSQARVDANRSAPAAGEYRHPGASDRSQSAGAVVVDGGNAKNSALMAKK 633
            SAAQSLAVALP SQAR DANR  PA GEYRHPGA DR+Q AGAVV++G NAKNSALMAKK
Sbjct: 112  SAAQSLAVALPASQARADANRPVPAGGEYRHPGAPDRAQPAGAVVMEGSNAKNSALMAKK 171

Query: 634  APTMPKPQWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLS 813
            APTMPKPQWHPPWKLYRVISGHLGWVRCIAV+PGNQ FVTGSADRTIKIWDLASGKLKLS
Sbjct: 172  APTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLS 231

Query: 814  LTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTID 993
            LTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTID
Sbjct: 232  LTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTID 291

Query: 994  VLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVA 1173
            VLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVA
Sbjct: 292  VLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVA 351

Query: 1174 GKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTV 1353
            GKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTV
Sbjct: 352  GKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTV 411

Query: 1354 NSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAE 1533
            NSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAE
Sbjct: 412  NSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAE 471

Query: 1534 ADKTIKVYREDDTATEETHPVSWKPEIIKRKRF 1632
            ADKTIKVY+EDDTATEETHPVSWKPEIIKRKRF
Sbjct: 472  ADKTIKVYKEDDTATEETHPVSWKPEIIKRKRF 504


>ref|XP_883554.1| PREDICTED: similar to Pleiotropic regulator 1 isoform 5 [Bos taurus]
          Length = 506

 Score =  988 bits (2554), Expect = 0.0
 Identities = 488/515 (94%), Positives = 493/515 (95%), Gaps = 2/515 (0%)
 Frame = +1

Query: 94   MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT 273
            MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
Sbjct: 1    MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT 60

Query: 274  SKENLKEKGPQNASDSYGHKQYPANQGQEVEYLVTGTHPYPPGPGVALTPDTKIQRMPSE 453
            SKENLKEK PQNASDSYGHKQYPANQGQEVEYLVTG         VALT DTKIQRMPSE
Sbjct: 61   SKENLKEKVPQNASDSYGHKQYPANQGQEVEYLVTG---------VALTADTKIQRMPSE 111

Query: 454  SAAQSLAVALPTSQARVDANRSAPAAGEYRHPGASDRSQSAGA--VVVDGGNAKNSALMA 627
            SAAQSLAVALP SQAR DANR  PA GEYRHPGA DR+Q AGA  VV++G NAKNSALMA
Sbjct: 112  SAAQSLAVALPASQARADANRPVPAGGEYRHPGAPDRAQPAGATSVVMEGSNAKNSALMA 171

Query: 628  KKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLK 807
            KKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV+PGNQ FVTGSADRTIKIWDLASGKLK
Sbjct: 172  KKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLK 231

Query: 808  LSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPT 987
            LSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPT
Sbjct: 232  LSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPT 291

Query: 988  IDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 1167
            IDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL
Sbjct: 292  IDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 351

Query: 1168 VAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTL 1347
            VAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTL
Sbjct: 352  VAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTL 411

Query: 1348 TVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLT 1527
            TVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLT
Sbjct: 412  TVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLT 471

Query: 1528 AEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF 1632
            AEADKTIKVY+EDDTATEETHPVSWKPEIIKRKRF
Sbjct: 472  AEADKTIKVYKEDDTATEETHPVSWKPEIIKRKRF 506


>ref|XP_608583.2| PREDICTED: similar to CG7568-PA [Bos taurus]
          Length = 441

 Score =  131 bits (330), Expect = 2e-30
 Identities = 90/340 (26%), Positives = 155/340 (45%), Gaps = 45/340 (13%)
 Frame = +1

Query: 676  LYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVS 855
            L++V+  H+  +  +A+      F+TGS DRT K+WD ASG+   +L GH + V  +  +
Sbjct: 110  LFKVLRAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELHTLEGHRNVVYAIAFN 169

Query: 856  TRSPYLFSCGE-DKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
                   + G  DK  K W +E  K    + GH + +  L  +P   ++ T S D+TA++
Sbjct: 170  NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 229

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD+++   V TL+GH+  + ++    +  +IITGS D T+ +W+   G+   TL  H   
Sbjct: 230  WDIQSGEEVFTLTGHSAEIISLSFNTSGNRIITGSFDHTVTVWEADTGRKVYTLIGHCAE 289

Query: 1213 VRAVVLHPRHYTFASGSPDNI-KQWKFPDGSFIQNLSGHN-AIINTL---------TVNS 1359
            + + V +       +GS D   K W   +G  +  L+GH+  I+++          T ++
Sbjct: 290  ISSAVFNWDCSLILTGSMDKTCKLWDAVNGKCVATLTGHDDEILDSCFDYTGKLIATASA 349

Query: 1360 DGV---------------------------------LVSGADNGTMHLWDWRTGYNFQRV 1440
            DG                                  L++G+ + T  +WD +TG   Q  
Sbjct: 350  DGTARIFSAATRECVTKLEGHEGEISKISFNPQGNRLLTGSSDKTARIWDAQTGQCLQ-- 407

Query: 1441 HAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVYR 1560
               V  G  D    IF+CAF+     ++T   D T +++R
Sbjct: 408  ---VLEGHTDE---IFSCAFNYKGDIIITGSKDNTCRIWR 441



 Score =  105 bits (261), Expect = 2e-22
 Identities = 61/247 (24%), Positives = 109/247 (44%), Gaps = 2/247 (0%)
 Frame = +1

Query: 673  KLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 852
            K Y    GH   + C++  P +    TGS D T K+WD+ SG+   +LTGH + +  +  
Sbjct: 194  KCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQSGEEVFTLTGHSAEIISLSF 253

Query: 853  STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
            +T    + +   D  V  W+ +  + +    GH + +     +    +++T S D T ++
Sbjct: 254  NTSGNRIITGSFDHTVTVWEADTGRKVYTLIGHCAEISSAVFNWDCSLILTGSMDKTCKL 313

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD      V TL+GH + +           I T S D T R++     +    L  H+  
Sbjct: 314  WDAVNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRECVTKLEGHEGE 373

Query: 1213 VRAVVLHPRHYTFASGSPDNIKQ-WKFPDGSFIQNLSGHNAIINTLTVNSDG-VLVSGAD 1386
            +  +  +P+     +GS D   + W    G  +Q L GH   I +   N  G ++++G+ 
Sbjct: 374  ISKISFNPQGNRLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGDIIITGSK 433

Query: 1387 NGTMHLW 1407
            + T  +W
Sbjct: 434  DNTCRIW 440


>ref|NP_777088.1| platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit
            (45kD) [Bos taurus]
          Length = 410

 Score =  128 bits (321), Expect = 2e-29
 Identities = 87/323 (26%), Positives = 142/323 (43%), Gaps = 22/323 (6%)
 Frame = +1

Query: 655  QWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHIST 834
            +W P       +SGH   V  +   P     V+ S D TIK+WD  +G  + +L GH  +
Sbjct: 93   EWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS 152

Query: 835  VRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSR 1014
            V  +        L SC  D  +K WD +  + IR  HGH   V  + + P  D +V+ SR
Sbjct: 153  VEDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASR 212

Query: 1015 DSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTL 1194
            D T ++W+V+T   V T +GH   V  VR       I + S+D T+R+W +   + +  L
Sbjct: 213  DKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272

Query: 1195 TNHKKSVRAVVLHPR-----------HYTFASGSP----------DNIKQWKFPDGSFIQ 1311
              H+  V  +   P              T  SG P            IK W    G  + 
Sbjct: 273  REHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLM 332

Query: 1312 NLSGHNAIINTLTVNSDG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIF 1488
             L GH+  +  +  +S G  ++S AD+ T+ +WD++     + ++A         E  + 
Sbjct: 333  TLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA--------HEHFVT 384

Query: 1489 ACAFDQSESRLLTAEADKTIKVY 1557
            +  F ++   ++T   D+T+KV+
Sbjct: 385  SLDFHKTAPYVVTGSVDQTVKVW 407



 Score = 86.7 bits (213), Expect = 7e-17
 Identities = 49/183 (26%), Positives = 85/183 (46%), Gaps = 22/183 (12%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSA--DRTIKIWDLASGKLKLSLTGHISTVRGVIVS 855
            +  +GH  WVR   V+P   G +  S   D+T+++W +A+ + K  L  H   V  +  +
Sbjct: 228  KTFTGHREWVRM--VRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWA 285

Query: 856  TRS--------------------PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLD 975
              S                    P+L S   DK +K WD+     +    GH + V G+ 
Sbjct: 286  PESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVL 345

Query: 976  LHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIR 1155
             H     +++C+ D T R+WD + K  + TL+ H + V ++      P ++TGS D T++
Sbjct: 346  FHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVK 405

Query: 1156 LWD 1164
            +W+
Sbjct: 406  VWE 408



 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 43/126 (34%), Positives = 70/126 (55%)
 Frame = +1

Query: 667  PWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGV 846
            P   Y  IS   G     + KPG    ++GS D+TIK+WD+++G   ++L GH + VRGV
Sbjct: 286  PESSYSSISEATGSETKKSGKPG-PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 344

Query: 847  IVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTA 1026
            +  +   ++ SC +DK ++ WD +  + ++  + H   V  LD H T   +VT S D T 
Sbjct: 345  LFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTV 404

Query: 1027 RIWDVR 1044
            ++W+ R
Sbjct: 405  KVWECR 410


>ref|XP_883815.1| PREDICTED: similar to F-box protein FBW7 isoform 1 isoform 6 [Bos
            taurus]
          Length = 706

 Score =  125 bits (314), Expect = 1e-28
 Identities = 89/294 (30%), Positives = 147/294 (50%), Gaps = 2/294 (0%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 861
            +V+ GH   V       GN+  V+GS D T+K+W   +GK   +L GH   V       R
Sbjct: 373  KVLKGHDDHVITCLQFCGNR-IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSS--QMR 429

Query: 862  SPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDV 1041
               + S   D+ +K W+ E  + I   +GH S V  + LH     +V+ SRD+T R+WD+
Sbjct: 430  DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDI 487

Query: 1042 RTKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVR 1218
             T   +H L GH   VA VRC Q    ++++G++D  +++WD        TL  H   V 
Sbjct: 488  ETGQCLHVLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 544

Query: 1219 AVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGT 1395
            ++     H    SGS D +I+ W    G+ I  L+GH ++ + + +  D +LVSG  + T
Sbjct: 545  SLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL-KDNILVSGNADST 601

Query: 1396 MHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 1557
            + +WD +TG   Q +      G    +S +    F  +++ ++T+  D T+K++
Sbjct: 602  VKIWDIKTGQCLQTLQ-----GPNKHQSAVTCLQF--NKNFVITSSDDGTVKLW 648



 Score =  124 bits (310), Expect = 4e-28
 Identities = 79/254 (31%), Positives = 134/254 (52%), Gaps = 4/254 (1%)
 Frame = +1

Query: 673  KLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 852
            K  R + GH G V    ++  +   ++GS DRT+K+W+  +G+   +L GH STVR + +
Sbjct: 411  KCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 468

Query: 853  STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
              +   + S   D  ++ WD+E  + +    GH++AV  +        +V+ + D   ++
Sbjct: 469  HEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKV 524

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD  T+  +HTL GHTN V +++       +++GS DT+IR+WD+  G    TLT H+  
Sbjct: 525  WDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSL 582

Query: 1213 VRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSG---HNAIINTLTVNSDGVLVSG 1380
               + L  +     SG+ D+ +K W    G  +Q L G   H + +  L  N + V+ S 
Sbjct: 583  TSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS- 639

Query: 1381 ADNGTMHLWDWRTG 1422
            +D+GT+ LWD +TG
Sbjct: 640  SDDGTVKLWDLKTG 653



 Score =  108 bits (269), Expect = 2e-23
 Identities = 71/242 (29%), Positives = 118/242 (48%), Gaps = 8/242 (3%)
 Frame = +1

Query: 694  GHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 873
            GH   VRC+ +    +  V+GS D T+++WD+ +G+    L GH++ VR V    R   +
Sbjct: 458  GHTSTVRCMHLH--EKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--V 513

Query: 874  FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKA 1053
             S   D  VK WD E    +    GH + VY L        +V+ S D++ R+WDV T  
Sbjct: 514  VSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGN 571

Query: 1054 SVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVL- 1230
             +HTL+GH +  + +  +  +  +++G+ D+T+++WD+  G+   TL    K   AV   
Sbjct: 572  CIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCL 629

Query: 1231 -HPRHYTFASGSPDNIKQWKFPDGSFIQNL-----SGHNAIINTLTV-NSDGVLVSGADN 1389
               +++   S     +K W    G FI+NL      G   ++  +   N+  V   G+ N
Sbjct: 630  QFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 689

Query: 1390 GT 1395
            GT
Sbjct: 690  GT 691



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 54/166 (32%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
 Frame = +1

Query: 685  VISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 864
            V+ GH+  VRC  V+   +  V+G+ D  +K+WD  +     +L GH + V  +      
Sbjct: 495  VLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--G 550

Query: 865  PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 1044
             ++ S   D  ++ WD+E    I    GH S   G++L   I  LV+ + DST +IWD++
Sbjct: 551  IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI--LVSGNADSTVKIWDIK 608

Query: 1045 TKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGK 1179
            T   + TL G     + V C Q  +  +IT S D T++LWDL  G+
Sbjct: 609  TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGE 654


>ref|XP_883785.1| PREDICTED: similar to F-box protein FBW7 isoform 3 isoform 5 [Bos
            taurus]
          Length = 589

 Score =  125 bits (314), Expect = 1e-28
 Identities = 89/294 (30%), Positives = 147/294 (50%), Gaps = 2/294 (0%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 861
            +V+ GH   V       GN+  V+GS D T+K+W   +GK   +L GH   V       R
Sbjct: 256  KVLKGHDDHVITCLQFCGNR-IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSS--QMR 312

Query: 862  SPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDV 1041
               + S   D+ +K W+ E  + I   +GH S V  + LH     +V+ SRD+T R+WD+
Sbjct: 313  DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDI 370

Query: 1042 RTKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVR 1218
             T   +H L GH   VA VRC Q    ++++G++D  +++WD        TL  H   V 
Sbjct: 371  ETGQCLHVLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 427

Query: 1219 AVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGT 1395
            ++     H    SGS D +I+ W    G+ I  L+GH ++ + + +  D +LVSG  + T
Sbjct: 428  SLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL-KDNILVSGNADST 484

Query: 1396 MHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 1557
            + +WD +TG   Q +      G    +S +    F  +++ ++T+  D T+K++
Sbjct: 485  VKIWDIKTGQCLQTLQ-----GPNKHQSAVTCLQF--NKNFVITSSDDGTVKLW 531



 Score =  124 bits (310), Expect = 4e-28
 Identities = 79/254 (31%), Positives = 134/254 (52%), Gaps = 4/254 (1%)
 Frame = +1

Query: 673  KLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 852
            K  R + GH G V    ++  +   ++GS DRT+K+W+  +G+   +L GH STVR + +
Sbjct: 294  KCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 351

Query: 853  STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
              +   + S   D  ++ WD+E  + +    GH++AV  +        +V+ + D   ++
Sbjct: 352  HEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKV 407

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD  T+  +HTL GHTN V +++       +++GS DT+IR+WD+  G    TLT H+  
Sbjct: 408  WDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSL 465

Query: 1213 VRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSG---HNAIINTLTVNSDGVLVSG 1380
               + L  +     SG+ D+ +K W    G  +Q L G   H + +  L  N + V+ S 
Sbjct: 466  TSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS- 522

Query: 1381 ADNGTMHLWDWRTG 1422
            +D+GT+ LWD +TG
Sbjct: 523  SDDGTVKLWDLKTG 536



 Score =  108 bits (269), Expect = 2e-23
 Identities = 71/242 (29%), Positives = 118/242 (48%), Gaps = 8/242 (3%)
 Frame = +1

Query: 694  GHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 873
            GH   VRC+ +    +  V+GS D T+++WD+ +G+    L GH++ VR V    R   +
Sbjct: 341  GHTSTVRCMHLH--EKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--V 396

Query: 874  FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKA 1053
             S   D  VK WD E    +    GH + VY L        +V+ S D++ R+WDV T  
Sbjct: 397  VSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGN 454

Query: 1054 SVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVL- 1230
             +HTL+GH +  + +  +  +  +++G+ D+T+++WD+  G+   TL    K   AV   
Sbjct: 455  CIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCL 512

Query: 1231 -HPRHYTFASGSPDNIKQWKFPDGSFIQNL-----SGHNAIINTLTV-NSDGVLVSGADN 1389
               +++   S     +K W    G FI+NL      G   ++  +   N+  V   G+ N
Sbjct: 513  QFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 572

Query: 1390 GT 1395
            GT
Sbjct: 573  GT 574



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 54/166 (32%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
 Frame = +1

Query: 685  VISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 864
            V+ GH+  VRC  V+   +  V+G+ D  +K+WD  +     +L GH + V  +      
Sbjct: 378  VLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--G 433

Query: 865  PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 1044
             ++ S   D  ++ WD+E    I    GH S   G++L   I  LV+ + DST +IWD++
Sbjct: 434  IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI--LVSGNADSTVKIWDIK 491

Query: 1045 TKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGK 1179
            T   + TL G     + V C Q  +  +IT S D T++LWDL  G+
Sbjct: 492  TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGE 537


>ref|XP_883749.1| PREDICTED: similar to F-box protein FBW7 isoform 2 isoform 4 [Bos
            taurus]
          Length = 629

 Score =  125 bits (314), Expect = 1e-28
 Identities = 89/294 (30%), Positives = 147/294 (50%), Gaps = 2/294 (0%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 861
            +V+ GH   V       GN+  V+GS D T+K+W   +GK   +L GH   V       R
Sbjct: 296  KVLKGHDDHVITCLQFCGNR-IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSS--QMR 352

Query: 862  SPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDV 1041
               + S   D+ +K W+ E  + I   +GH S V  + LH     +V+ SRD+T R+WD+
Sbjct: 353  DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDI 410

Query: 1042 RTKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVR 1218
             T   +H L GH   VA VRC Q    ++++G++D  +++WD        TL  H   V 
Sbjct: 411  ETGQCLHVLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 467

Query: 1219 AVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGT 1395
            ++     H    SGS D +I+ W    G+ I  L+GH ++ + + +  D +LVSG  + T
Sbjct: 468  SLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL-KDNILVSGNADST 524

Query: 1396 MHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 1557
            + +WD +TG   Q +      G    +S +    F  +++ ++T+  D T+K++
Sbjct: 525  VKIWDIKTGQCLQTLQ-----GPNKHQSAVTCLQF--NKNFVITSSDDGTVKLW 571



 Score =  124 bits (310), Expect = 4e-28
 Identities = 79/254 (31%), Positives = 134/254 (52%), Gaps = 4/254 (1%)
 Frame = +1

Query: 673  KLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 852
            K  R + GH G V    ++  +   ++GS DRT+K+W+  +G+   +L GH STVR + +
Sbjct: 334  KCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 391

Query: 853  STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
              +   + S   D  ++ WD+E  + +    GH++AV  +        +V+ + D   ++
Sbjct: 392  HEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKV 447

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD  T+  +HTL GHTN V +++       +++GS DT+IR+WD+  G    TLT H+  
Sbjct: 448  WDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSL 505

Query: 1213 VRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSG---HNAIINTLTVNSDGVLVSG 1380
               + L  +     SG+ D+ +K W    G  +Q L G   H + +  L  N + V+ S 
Sbjct: 506  TSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS- 562

Query: 1381 ADNGTMHLWDWRTG 1422
            +D+GT+ LWD +TG
Sbjct: 563  SDDGTVKLWDLKTG 576



 Score =  108 bits (269), Expect = 2e-23
 Identities = 71/242 (29%), Positives = 118/242 (48%), Gaps = 8/242 (3%)
 Frame = +1

Query: 694  GHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 873
            GH   VRC+ +    +  V+GS D T+++WD+ +G+    L GH++ VR V    R   +
Sbjct: 381  GHTSTVRCMHLH--EKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--V 436

Query: 874  FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKA 1053
             S   D  VK WD E    +    GH + VY L        +V+ S D++ R+WDV T  
Sbjct: 437  VSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGN 494

Query: 1054 SVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVL- 1230
             +HTL+GH +  + +  +  +  +++G+ D+T+++WD+  G+   TL    K   AV   
Sbjct: 495  CIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCL 552

Query: 1231 -HPRHYTFASGSPDNIKQWKFPDGSFIQNL-----SGHNAIINTLTV-NSDGVLVSGADN 1389
               +++   S     +K W    G FI+NL      G   ++  +   N+  V   G+ N
Sbjct: 553  QFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 612

Query: 1390 GT 1395
            GT
Sbjct: 613  GT 614



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 54/166 (32%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
 Frame = +1

Query: 685  VISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 864
            V+ GH+  VRC  V+   +  V+G+ D  +K+WD  +     +L GH + V  +      
Sbjct: 418  VLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--G 473

Query: 865  PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 1044
             ++ S   D  ++ WD+E    I    GH S   G++L   I  LV+ + DST +IWD++
Sbjct: 474  IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI--LVSGNADSTVKIWDIK 531

Query: 1045 TKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGK 1179
            T   + TL G     + V C Q  +  +IT S D T++LWDL  G+
Sbjct: 532  TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGE 577


>ref|XP_613742.2| PREDICTED: similar to F-box protein FBW7 isoform 1 isoform 1 [Bos
            taurus]
          Length = 706

 Score =  125 bits (314), Expect = 1e-28
 Identities = 89/294 (30%), Positives = 147/294 (50%), Gaps = 2/294 (0%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 861
            +V+ GH   V       GN+  V+GS D T+K+W   +GK   +L GH   V       R
Sbjct: 373  KVLKGHDDHVITCLQFCGNR-IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSS--QMR 429

Query: 862  SPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDV 1041
               + S   D+ +K W+ E  + I   +GH S V  + LH     +V+ SRD+T R+WD+
Sbjct: 430  DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDI 487

Query: 1042 RTKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVR 1218
             T   +H L GH   VA VRC Q    ++++G++D  +++WD        TL  H   V 
Sbjct: 488  ETGQCLHVLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 544

Query: 1219 AVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGT 1395
            ++     H    SGS D +I+ W    G+ I  L+GH ++ + + +  D +LVSG  + T
Sbjct: 545  SLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL-KDNILVSGNADST 601

Query: 1396 MHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 1557
            + +WD +TG   Q +      G    +S +    F  +++ ++T+  D T+K++
Sbjct: 602  VKIWDIKTGQCLQTLQ-----GPNKHQSAVTCLQF--NKNFVITSSDDGTVKLW 648



 Score =  124 bits (310), Expect = 4e-28
 Identities = 79/254 (31%), Positives = 134/254 (52%), Gaps = 4/254 (1%)
 Frame = +1

Query: 673  KLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 852
            K  R + GH G V    ++  +   ++GS DRT+K+W+  +G+   +L GH STVR + +
Sbjct: 411  KCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 468

Query: 853  STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
              +   + S   D  ++ WD+E  + +    GH++AV  +        +V+ + D   ++
Sbjct: 469  HEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKV 524

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD  T+  +HTL GHTN V +++       +++GS DT+IR+WD+  G    TLT H+  
Sbjct: 525  WDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSL 582

Query: 1213 VRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSG---HNAIINTLTVNSDGVLVSG 1380
               + L  +     SG+ D+ +K W    G  +Q L G   H + +  L  N + V+ S 
Sbjct: 583  TSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS- 639

Query: 1381 ADNGTMHLWDWRTG 1422
            +D+GT+ LWD +TG
Sbjct: 640  SDDGTVKLWDLKTG 653



 Score =  108 bits (269), Expect = 2e-23
 Identities = 71/242 (29%), Positives = 118/242 (48%), Gaps = 8/242 (3%)
 Frame = +1

Query: 694  GHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 873
            GH   VRC+ +    +  V+GS D T+++WD+ +G+    L GH++ VR V    R   +
Sbjct: 458  GHTSTVRCMHLH--EKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--V 513

Query: 874  FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKA 1053
             S   D  VK WD E    +    GH + VY L        +V+ S D++ R+WDV T  
Sbjct: 514  VSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGN 571

Query: 1054 SVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVL- 1230
             +HTL+GH +  + +  +  +  +++G+ D+T+++WD+  G+   TL    K   AV   
Sbjct: 572  CIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCL 629

Query: 1231 -HPRHYTFASGSPDNIKQWKFPDGSFIQNL-----SGHNAIINTLTV-NSDGVLVSGADN 1389
               +++   S     +K W    G FI+NL      G   ++  +   N+  V   G+ N
Sbjct: 630  QFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 689

Query: 1390 GT 1395
            GT
Sbjct: 690  GT 691



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 54/166 (32%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
 Frame = +1

Query: 685  VISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 864
            V+ GH+  VRC  V+   +  V+G+ D  +K+WD  +     +L GH + V  +      
Sbjct: 495  VLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--G 550

Query: 865  PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 1044
             ++ S   D  ++ WD+E    I    GH S   G++L   I  LV+ + DST +IWD++
Sbjct: 551  IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI--LVSGNADSTVKIWDIK 608

Query: 1045 TKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGK 1179
            T   + TL G     + V C Q  +  +IT S D T++LWDL  G+
Sbjct: 609  TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGE 654


  Database: RefSeqBP
    Posted date:  Aug 1, 2006  7:14 PM
  Number of letters in database: 16,112,626
  Number of sequences in database:  33,508
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,652,269
Number of Sequences: 33508
Number of extensions: 1734765
Number of successful extensions: 8040
Number of sequences better than 1.0e-05: 10
Number of HSP's better than  0.0 without gapping: 4680
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6542
length of database: 16,112,626
effective HSP length: 109
effective length of database: 12,460,254
effective search space used: 7438771638
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

BLASTX 2.2.10 [Oct-19-2004]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AMP01_0016_F01
         (2121 letters)

Database: RefSeqCP 
           33,732 sequences; 19,266,565 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|XP_855313.1| PREDICTED: similar to Pleiotropic regulator 1 [...  1019   0.0  
Alignment   gi|XP_862542.1| PREDICTED: similar to Katanin p80 WD40-containi...   131   2e-30
Alignment   gi|XP_850865.1| PREDICTED: similar to Katanin p80 WD40-containi...   131   2e-30
Alignment   gi|XP_537775.2| PREDICTED: similar to platelet-activating facto...   128   2e-29
Alignment   gi|XP_854482.1| PREDICTED: similar to platelet-activating facto...   128   2e-29
Alignment   gi|XP_868508.1| PREDICTED: similar to platelet-activating facto...   128   2e-29
Alignment   gi|XP_534593.2| PREDICTED: similar to CG7568-PA [Canis familiaris]   127   4e-29
Alignment   gi|XP_868519.1| PREDICTED: similar to platelet-activating facto...   126   7e-29
Alignment   gi|XP_532689.2| PREDICTED: similar to F-box protein FBW7 isofor...   125   2e-28
Alignment   gi|XP_867720.1| PREDICTED: similar to F-box protein FBW7 isofor...   125   2e-28

>ref|XP_855313.1| PREDICTED: similar to Pleiotropic regulator 1 [Canis familiaris]
          Length = 547

 Score = 1019 bits (2635), Expect = 0.0
 Identities = 499/535 (93%), Positives = 509/535 (95%), Gaps = 2/535 (0%)
 Frame = +1

Query: 34   FVCCWLVLLPRRSDGIKSGVMVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESH 213
            F+  W+VL         +  + EEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESH
Sbjct: 22   FLSAWIVL---------TSALHEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESH 72

Query: 214  KRKMAIKLRNEYGPVLHMPTSKENLKEKGPQNASDSYGHKQYPANQGQEVEYLVTGTHPY 393
            KRKMAIKLRNEYGPVLHMPTSKEN KEK PQNASDSYGHKQYPANQGQEVEYLVTGTHPY
Sbjct: 73   KRKMAIKLRNEYGPVLHMPTSKENFKEKCPQNASDSYGHKQYPANQGQEVEYLVTGTHPY 132

Query: 394  PPGPGVALTPDTKIQRMPSESAAQSLAVALPTSQARVDANRSAPAAGEYRHPGASDRSQS 573
            PPGPGVALT DTKIQRMPSESAAQSLAVALP+SQ RVDANRSAPA GEYRHPG SDRSQ 
Sbjct: 133  PPGPGVALTADTKIQRMPSESAAQSLAVALPSSQTRVDANRSAPAGGEYRHPGTSDRSQP 192

Query: 574  AG--AVVVDGGNAKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVKPGNQGF 747
            AG  + V++ GNAKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV+PGNQ F
Sbjct: 193  AGMTSAVMEAGNAKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWF 252

Query: 748  VTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK 927
            VTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK
Sbjct: 253  VTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK 312

Query: 928  VIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQ 1107
            VIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQ
Sbjct: 313  VIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQ 372

Query: 1108 AAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWK 1287
            AAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWK
Sbjct: 373  AAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWK 432

Query: 1288 FPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSL 1467
            FPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSL
Sbjct: 433  FPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSL 492

Query: 1468 DSESGIFACAFDQSESRLLTAEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF 1632
            DSESGIFACAFDQSESRLLTAEADKTIKVY+EDDTATEETHPVSWKPEIIKRKRF
Sbjct: 493  DSESGIFACAFDQSESRLLTAEADKTIKVYKEDDTATEETHPVSWKPEIIKRKRF 547


>ref|XP_862542.1| PREDICTED: similar to Katanin p80 WD40-containing subunit B1 (Katanin
            p80 subunit B1) (p80 katanin) isoform 2 [Canis
            familiaris]
          Length = 655

 Score =  131 bits (330), Expect = 2e-30
 Identities = 68/249 (27%), Positives = 114/249 (45%), Gaps = 1/249 (0%)
 Frame = +1

Query: 670  WKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVI 849
            WKL  +++        +  K   +   TG  D  + +W +      +SLTGH S V  V 
Sbjct: 11   WKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVR 70

Query: 850  VSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTAR 1029
            ++T    + +  +   ++ WDLE  K++R   GH + +  LD HP  + + + S+D+  +
Sbjct: 71   LNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIK 130

Query: 1030 IWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKK 1209
            +WD+R K  V    GH+ AV  +R       + + + D T++LWDL AGK       H  
Sbjct: 131  LWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTG 190

Query: 1210 SVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGAD 1386
             V  V  HP  Y  ASGS D  I+ W       +  + G    + ++  N DG  +    
Sbjct: 191  PVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGC 250

Query: 1387 NGTMHLWDW 1413
              ++ ++ W
Sbjct: 251  QDSLRVYGW 259


>ref|XP_850865.1| PREDICTED: similar to Katanin p80 WD40-containing subunit B1 (Katanin
            p80 subunit B1) (p80 katanin) isoform 1 [Canis
            familiaris]
          Length = 655

 Score =  131 bits (330), Expect = 2e-30
 Identities = 68/249 (27%), Positives = 114/249 (45%), Gaps = 1/249 (0%)
 Frame = +1

Query: 670  WKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVI 849
            WKL  +++        +  K   +   TG  D  + +W +      +SLTGH S V  V 
Sbjct: 11   WKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVR 70

Query: 850  VSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTAR 1029
            ++T    + +  +   ++ WDLE  K++R   GH + +  LD HP  + + + S+D+  +
Sbjct: 71   LNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIK 130

Query: 1030 IWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKK 1209
            +WD+R K  V    GH+ AV  +R       + + + D T++LWDL AGK       H  
Sbjct: 131  LWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTG 190

Query: 1210 SVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGAD 1386
             V  V  HP  Y  ASGS D  I+ W       +  + G    + ++  N DG  +    
Sbjct: 191  PVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGC 250

Query: 1387 NGTMHLWDW 1413
              ++ ++ W
Sbjct: 251  QDSLRVYGW 259


>ref|XP_537775.2| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
            subunit isoform 1 [Canis familiaris]
          Length = 372

 Score =  128 bits (322), Expect = 2e-29
 Identities = 87/323 (26%), Positives = 143/323 (44%), Gaps = 22/323 (6%)
 Frame = +1

Query: 655  QWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHIST 834
            +W P       +SGH   V  +   P     V+ S D TIK+WD  +G  + +L GH  +
Sbjct: 55   EWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS 114

Query: 835  VRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSR 1014
            V+ +        L SC  D  +K WD +  + IR  HGH   V  + + P  D +V+ SR
Sbjct: 115  VQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASR 174

Query: 1015 DSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTL 1194
            D T ++W+V+T   V T +GH   V  VR       I + S+D T+R+W +   + +  L
Sbjct: 175  DKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 234

Query: 1195 TNHKKSVRAVVLHPR-----------HYTFASGSP----------DNIKQWKFPDGSFIQ 1311
              H+  V  +   P              T  SG P            IK W    G  + 
Sbjct: 235  REHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLM 294

Query: 1312 NLSGHNAIINTLTVNSDG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIF 1488
             L GH+  +  +  +S G  ++S AD+ T+ +WD++     + ++A         E  + 
Sbjct: 295  TLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA--------HEHFVT 346

Query: 1489 ACAFDQSESRLLTAEADKTIKVY 1557
            +  F ++   ++T   D+T+KV+
Sbjct: 347  SLDFHKTAPYVVTGSVDQTVKVW 369



 Score = 86.7 bits (213), Expect = 8e-17
 Identities = 49/183 (26%), Positives = 85/183 (46%), Gaps = 22/183 (12%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSA--DRTIKIWDLASGKLKLSLTGHISTVRGVIVS 855
            +  +GH  WVR   V+P   G +  S   D+T+++W +A+ + K  L  H   V  +  +
Sbjct: 190  KTFTGHREWVRM--VRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWA 247

Query: 856  TRS--------------------PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLD 975
              S                    P+L S   DK +K WD+     +    GH + V G+ 
Sbjct: 248  PESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVL 307

Query: 976  LHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIR 1155
             H     +++C+ D T R+WD + K  + TL+ H + V ++      P ++TGS D T++
Sbjct: 308  FHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVK 367

Query: 1156 LWD 1164
            +W+
Sbjct: 368  VWE 370



 Score = 84.0 bits (206), Expect = 5e-16
 Identities = 43/126 (34%), Positives = 70/126 (55%)
 Frame = +1

Query: 667  PWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGV 846
            P   Y  IS   G     + KPG    ++GS D+TIK+WD+++G   ++L GH + VRGV
Sbjct: 248  PESSYSSISEATGSETKKSGKPG-PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 306

Query: 847  IVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTA 1026
            +  +   ++ SC +DK ++ WD +  + ++  + H   V  LD H T   +VT S D T 
Sbjct: 307  LFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTV 366

Query: 1027 RIWDVR 1044
            ++W+ R
Sbjct: 367  KVWECR 372


>ref|XP_854482.1| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
            subunit isoform 2 [Canis familiaris]
          Length = 410

 Score =  128 bits (322), Expect = 2e-29
 Identities = 87/323 (26%), Positives = 143/323 (44%), Gaps = 22/323 (6%)
 Frame = +1

Query: 655  QWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHIST 834
            +W P       +SGH   V  +   P     V+ S D TIK+WD  +G  + +L GH  +
Sbjct: 93   EWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS 152

Query: 835  VRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSR 1014
            V+ +        L SC  D  +K WD +  + IR  HGH   V  + + P  D +V+ SR
Sbjct: 153  VQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASR 212

Query: 1015 DSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTL 1194
            D T ++W+V+T   V T +GH   V  VR       I + S+D T+R+W +   + +  L
Sbjct: 213  DKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272

Query: 1195 TNHKKSVRAVVLHPR-----------HYTFASGSP----------DNIKQWKFPDGSFIQ 1311
              H+  V  +   P              T  SG P            IK W    G  + 
Sbjct: 273  REHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLM 332

Query: 1312 NLSGHNAIINTLTVNSDG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIF 1488
             L GH+  +  +  +S G  ++S AD+ T+ +WD++     + ++A         E  + 
Sbjct: 333  TLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA--------HEHFVT 384

Query: 1489 ACAFDQSESRLLTAEADKTIKVY 1557
            +  F ++   ++T   D+T+KV+
Sbjct: 385  SLDFHKTAPYVVTGSVDQTVKVW 407



 Score = 86.7 bits (213), Expect = 8e-17
 Identities = 49/183 (26%), Positives = 85/183 (46%), Gaps = 22/183 (12%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSA--DRTIKIWDLASGKLKLSLTGHISTVRGVIVS 855
            +  +GH  WVR   V+P   G +  S   D+T+++W +A+ + K  L  H   V  +  +
Sbjct: 228  KTFTGHREWVRM--VRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWA 285

Query: 856  TRS--------------------PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLD 975
              S                    P+L S   DK +K WD+     +    GH + V G+ 
Sbjct: 286  PESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVL 345

Query: 976  LHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIR 1155
             H     +++C+ D T R+WD + K  + TL+ H + V ++      P ++TGS D T++
Sbjct: 346  FHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVK 405

Query: 1156 LWD 1164
            +W+
Sbjct: 406  VWE 408



 Score = 84.0 bits (206), Expect = 5e-16
 Identities = 43/126 (34%), Positives = 70/126 (55%)
 Frame = +1

Query: 667  PWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGV 846
            P   Y  IS   G     + KPG    ++GS D+TIK+WD+++G   ++L GH + VRGV
Sbjct: 286  PESSYSSISEATGSETKKSGKPG-PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 344

Query: 847  IVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTA 1026
            +  +   ++ SC +DK ++ WD +  + ++  + H   V  LD H T   +VT S D T 
Sbjct: 345  LFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTV 404

Query: 1027 RIWDVR 1044
            ++W+ R
Sbjct: 405  KVWECR 410


>ref|XP_868508.1| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
            subunit isoform 3 [Canis familiaris]
          Length = 345

 Score =  128 bits (322), Expect = 2e-29
 Identities = 87/323 (26%), Positives = 143/323 (44%), Gaps = 22/323 (6%)
 Frame = +1

Query: 655  QWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHIST 834
            +W P       +SGH   V  +   P     V+ S D TIK+WD  +G  + +L GH  +
Sbjct: 28   EWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS 87

Query: 835  VRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSR 1014
            V+ +        L SC  D  +K WD +  + IR  HGH   V  + + P  D +V+ SR
Sbjct: 88   VQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASR 147

Query: 1015 DSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTL 1194
            D T ++W+V+T   V T +GH   V  VR       I + S+D T+R+W +   + +  L
Sbjct: 148  DKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 207

Query: 1195 TNHKKSVRAVVLHPR-----------HYTFASGSP----------DNIKQWKFPDGSFIQ 1311
              H+  V  +   P              T  SG P            IK W    G  + 
Sbjct: 208  REHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLM 267

Query: 1312 NLSGHNAIINTLTVNSDG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIF 1488
             L GH+  +  +  +S G  ++S AD+ T+ +WD++     + ++A         E  + 
Sbjct: 268  TLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA--------HEHFVT 319

Query: 1489 ACAFDQSESRLLTAEADKTIKVY 1557
            +  F ++   ++T   D+T+KV+
Sbjct: 320  SLDFHKTAPYVVTGSVDQTVKVW 342



 Score = 86.7 bits (213), Expect = 8e-17
 Identities = 49/183 (26%), Positives = 85/183 (46%), Gaps = 22/183 (12%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSA--DRTIKIWDLASGKLKLSLTGHISTVRGVIVS 855
            +  +GH  WVR   V+P   G +  S   D+T+++W +A+ + K  L  H   V  +  +
Sbjct: 163  KTFTGHREWVRM--VRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWA 220

Query: 856  TRS--------------------PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLD 975
              S                    P+L S   DK +K WD+     +    GH + V G+ 
Sbjct: 221  PESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVL 280

Query: 976  LHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIR 1155
             H     +++C+ D T R+WD + K  + TL+ H + V ++      P ++TGS D T++
Sbjct: 281  FHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVK 340

Query: 1156 LWD 1164
            +W+
Sbjct: 341  VWE 343



 Score = 84.0 bits (206), Expect = 5e-16
 Identities = 43/126 (34%), Positives = 70/126 (55%)
 Frame = +1

Query: 667  PWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGV 846
            P   Y  IS   G     + KPG    ++GS D+TIK+WD+++G   ++L GH + VRGV
Sbjct: 221  PESSYSSISEATGSETKKSGKPG-PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 279

Query: 847  IVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTA 1026
            +  +   ++ SC +DK ++ WD +  + ++  + H   V  LD H T   +VT S D T 
Sbjct: 280  LFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTV 339

Query: 1027 RIWDVR 1044
            ++W+ R
Sbjct: 340  KVWECR 345


>ref|XP_534593.2| PREDICTED: similar to CG7568-PA [Canis familiaris]
          Length = 415

 Score =  127 bits (319), Expect = 4e-29
 Identities = 80/297 (26%), Positives = 143/297 (48%), Gaps = 3/297 (1%)
 Frame = +1

Query: 676  LYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVS 855
            L++V+  H+  +  +A+      F+TGS DRT K+WD ASG+   +L GH + V  +  +
Sbjct: 84   LFKVLRAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELHTLEGHRNVVYAIAFN 143

Query: 856  TRSPYLFSCGE-DKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
                   + G  DK  K W +E  K    + GH + +  L  +P   ++ T S D+TA++
Sbjct: 144  NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD+++   V TL GH+  + ++    +  +I+TGS D T+ +W+   G+   TL  H   
Sbjct: 204  WDIQSGEEVFTLRGHSAEIISLSFNTSGDRIVTGSFDHTVAVWEADTGRKVYTLIGHCAE 263

Query: 1213 VRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGAD- 1386
            + + + +       +GS D     W   +G  +  L+GH+  I     +  G L++ A  
Sbjct: 264  ISSALFNWDCSLILTGSMDKTCMLWDASNGKCVATLTGHDDEILDSCFDYTGKLIATASA 323

Query: 1387 NGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 1557
            +GT  ++   T     ++           E  I   +F+   +RLLT  AD+T +++
Sbjct: 324  DGTARVFSAATRKCLTKLEG--------HEGEISKISFNPQGNRLLTGSADETARIW 372



 Score =  103 bits (257), Expect = 7e-22
 Identities = 61/247 (24%), Positives = 107/247 (43%), Gaps = 2/247 (0%)
 Frame = +1

Query: 673  KLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 852
            K Y    GH   + C++  P +    TGS D T K+WD+ SG+   +L GH + +  +  
Sbjct: 168  KCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQSGEEVFTLRGHSAEIISLSF 227

Query: 853  STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
            +T    + +   D  V  W+ +  + +    GH + +     +    +++T S D T  +
Sbjct: 228  NTSGDRIVTGSFDHTVAVWEADTGRKVYTLIGHCAEISSALFNWDCSLILTGSMDKTCML 287

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD      V TL+GH + +           I T S D T R++     K    L  H+  
Sbjct: 288  WDASNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARVFSAATRKCLTKLEGHEGE 347

Query: 1213 VRAVVLHPRHYTFASGSPDNIKQ-WKFPDGSFIQNLSGHNAIINTLTVNSDG-VLVSGAD 1386
            +  +  +P+     +GS D   + W    G  +Q L GH   I +   N  G ++++G+ 
Sbjct: 348  ISKISFNPQGNRLLTGSADETARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGDIIITGSK 407

Query: 1387 NGTMHLW 1407
            + T  +W
Sbjct: 408  DNTCRIW 414


>ref|XP_868519.1| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
            subunit isoform 5 [Canis familiaris]
          Length = 415

 Score =  126 bits (317), Expect = 7e-29
 Identities = 87/328 (26%), Positives = 143/328 (43%), Gaps = 27/328 (8%)
 Frame = +1

Query: 655  QWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHIST 834
            +W P       +SGH   V  +   P     V+ S D TIK+WD  +G  + +L GH  +
Sbjct: 93   EWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS 152

Query: 835  VRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSR 1014
            V+ +        L SC  D  +K WD +  + IR  HGH   V  + + P  D +V+ SR
Sbjct: 153  VQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASR 212

Query: 1015 DSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTL 1194
            D T ++W+V+T   V T +GH   V  VR       I + S+D T+R+W +   + +  L
Sbjct: 213  DKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272

Query: 1195 TNHKKSVRAVVLHPRH----------------YTFASGSP----------DNIKQWKFPD 1296
              H+  V  +   P                   T  SG P            IK W    
Sbjct: 273  REHEHVVECISWAPESSYSSISEATGSEEENPRTKKSGKPGPFLLSGSRDKTIKMWDVST 332

Query: 1297 GSFIQNLSGHNAIINTLTVNSDG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDS 1473
            G  +  L GH+  +  +  +S G  ++S AD+ T+ +WD++     + ++A         
Sbjct: 333  GMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA--------H 384

Query: 1474 ESGIFACAFDQSESRLLTAEADKTIKVY 1557
            E  + +  F ++   ++T   D+T+KV+
Sbjct: 385  EHFVTSLDFHKTAPYVVTGSVDQTVKVW 412



 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 49/188 (26%), Positives = 85/188 (45%), Gaps = 27/188 (14%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSA--DRTIKIWDLASGKLKLSLTGHISTVRGVIVS 855
            +  +GH  WVR   V+P   G +  S   D+T+++W +A+ + K  L  H   V  +  +
Sbjct: 228  KTFTGHREWVRM--VRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWA 285

Query: 856  TRS-------------------------PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSA 960
              S                         P+L S   DK +K WD+     +    GH + 
Sbjct: 286  PESSYSSISEATGSEEENPRTKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 345

Query: 961  VYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSH 1140
            V G+  H     +++C+ D T R+WD + K  + TL+ H + V ++      P ++TGS 
Sbjct: 346  VRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSV 405

Query: 1141 DTTIRLWD 1164
            D T+++W+
Sbjct: 406  DQTVKVWE 413



 Score = 83.6 bits (205), Expect = 7e-16
 Identities = 38/106 (35%), Positives = 64/106 (60%)
 Frame = +1

Query: 727  KPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKC 906
            KPG    ++GS D+TIK+WD+++G   ++L GH + VRGV+  +   ++ SC +DK ++ 
Sbjct: 311  KPG-PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRV 369

Query: 907  WDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 1044
            WD +  + ++  + H   V  LD H T   +VT S D T ++W+ R
Sbjct: 370  WDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 415


>ref|XP_532689.2| PREDICTED: similar to F-box protein FBW7 isoform 3 isoform 1 [Canis
            familiaris]
          Length = 589

 Score =  125 bits (314), Expect = 2e-28
 Identities = 89/294 (30%), Positives = 147/294 (50%), Gaps = 2/294 (0%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 861
            +V+ GH   V       GN+  V+GS D T+K+W   +GK   +L GH   V       R
Sbjct: 256  KVLKGHDDHVITCLQFCGNR-IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSS--QMR 312

Query: 862  SPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDV 1041
               + S   D+ +K W+ E  + I   +GH S V  + LH     +V+ SRD+T R+WD+
Sbjct: 313  DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDI 370

Query: 1042 RTKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVR 1218
             T   +H L GH   VA VRC Q    ++++G++D  +++WD        TL  H   V 
Sbjct: 371  ETGQCLHVLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 427

Query: 1219 AVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGT 1395
            ++     H    SGS D +I+ W    G+ I  L+GH ++ + + +  D +LVSG  + T
Sbjct: 428  SLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL-KDNILVSGNADST 484

Query: 1396 MHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 1557
            + +WD +TG   Q +      G    +S +    F  +++ ++T+  D T+K++
Sbjct: 485  VKIWDIKTGQCLQTLQ-----GPNKHQSAVTCLQF--NKNFVITSSDDGTVKLW 531



 Score =  124 bits (310), Expect = 5e-28
 Identities = 79/254 (31%), Positives = 134/254 (52%), Gaps = 4/254 (1%)
 Frame = +1

Query: 673  KLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 852
            K  R + GH G V    ++  +   ++GS DRT+K+W+  +G+   +L GH STVR + +
Sbjct: 294  KCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 351

Query: 853  STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
              +   + S   D  ++ WD+E  + +    GH++AV  +        +V+ + D   ++
Sbjct: 352  HEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKV 407

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD  T+  +HTL GHTN V +++       +++GS DT+IR+WD+  G    TLT H+  
Sbjct: 408  WDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSL 465

Query: 1213 VRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSG---HNAIINTLTVNSDGVLVSG 1380
               + L  +     SG+ D+ +K W    G  +Q L G   H + +  L  N + V+ S 
Sbjct: 466  TSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS- 522

Query: 1381 ADNGTMHLWDWRTG 1422
            +D+GT+ LWD +TG
Sbjct: 523  SDDGTVKLWDLKTG 536



 Score =  108 bits (269), Expect = 3e-23
 Identities = 71/242 (29%), Positives = 118/242 (48%), Gaps = 8/242 (3%)
 Frame = +1

Query: 694  GHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 873
            GH   VRC+ +    +  V+GS D T+++WD+ +G+    L GH++ VR V    R   +
Sbjct: 341  GHTSTVRCMHLH--EKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--V 396

Query: 874  FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKA 1053
             S   D  VK WD E    +    GH + VY L        +V+ S D++ R+WDV T  
Sbjct: 397  VSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGN 454

Query: 1054 SVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVL- 1230
             +HTL+GH +  + +  +  +  +++G+ D+T+++WD+  G+   TL    K   AV   
Sbjct: 455  CIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCL 512

Query: 1231 -HPRHYTFASGSPDNIKQWKFPDGSFIQNL-----SGHNAIINTLTV-NSDGVLVSGADN 1389
               +++   S     +K W    G FI+NL      G   ++  +   N+  V   G+ N
Sbjct: 513  QFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 572

Query: 1390 GT 1395
            GT
Sbjct: 573  GT 574



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 54/166 (32%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
 Frame = +1

Query: 685  VISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 864
            V+ GH+  VRC  V+   +  V+G+ D  +K+WD  +     +L GH + V  +      
Sbjct: 378  VLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--G 433

Query: 865  PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 1044
             ++ S   D  ++ WD+E    I    GH S   G++L   I  LV+ + DST +IWD++
Sbjct: 434  IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI--LVSGNADSTVKIWDIK 491

Query: 1045 TKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGK 1179
            T   + TL G     + V C Q  +  +IT S D T++LWDL  G+
Sbjct: 492  TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGE 537


>ref|XP_867720.1| PREDICTED: similar to F-box protein FBW7 isoform 2 isoform 5 [Canis
            familiaris]
          Length = 637

 Score =  125 bits (314), Expect = 2e-28
 Identities = 89/294 (30%), Positives = 147/294 (50%), Gaps = 2/294 (0%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 861
            +V+ GH   V       GN+  V+GS D T+K+W   +GK   +L GH   V       R
Sbjct: 304  KVLKGHDDHVITCLQFCGNR-IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSS--QMR 360

Query: 862  SPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDV 1041
               + S   D+ +K W+ E  + I   +GH S V  + LH     +V+ SRD+T R+WD+
Sbjct: 361  DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDI 418

Query: 1042 RTKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVR 1218
             T   +H L GH   VA VRC Q    ++++G++D  +++WD        TL  H   V 
Sbjct: 419  ETGQCLHVLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 475

Query: 1219 AVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGT 1395
            ++     H    SGS D +I+ W    G+ I  L+GH ++ + + +  D +LVSG  + T
Sbjct: 476  SLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL-KDNILVSGNADST 532

Query: 1396 MHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 1557
            + +WD +TG   Q +      G    +S +    F  +++ ++T+  D T+K++
Sbjct: 533  VKIWDIKTGQCLQTLQ-----GPNKHQSAVTCLQF--NKNFVITSSDDGTVKLW 579



 Score =  124 bits (310), Expect = 5e-28
 Identities = 79/254 (31%), Positives = 134/254 (52%), Gaps = 4/254 (1%)
 Frame = +1

Query: 673  KLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 852
            K  R + GH G V    ++  +   ++GS DRT+K+W+  +G+   +L GH STVR + +
Sbjct: 342  KCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 399

Query: 853  STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
              +   + S   D  ++ WD+E  + +    GH++AV  +        +V+ + D   ++
Sbjct: 400  HEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKV 455

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD  T+  +HTL GHTN V +++       +++GS DT+IR+WD+  G    TLT H+  
Sbjct: 456  WDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSL 513

Query: 1213 VRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSG---HNAIINTLTVNSDGVLVSG 1380
               + L  +     SG+ D+ +K W    G  +Q L G   H + +  L  N + V+ S 
Sbjct: 514  TSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS- 570

Query: 1381 ADNGTMHLWDWRTG 1422
            +D+GT+ LWD +TG
Sbjct: 571  SDDGTVKLWDLKTG 584



 Score =  108 bits (269), Expect = 3e-23
 Identities = 71/242 (29%), Positives = 118/242 (48%), Gaps = 8/242 (3%)
 Frame = +1

Query: 694  GHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 873
            GH   VRC+ +    +  V+GS D T+++WD+ +G+    L GH++ VR V    R   +
Sbjct: 389  GHTSTVRCMHLH--EKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--V 444

Query: 874  FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKA 1053
             S   D  VK WD E    +    GH + VY L        +V+ S D++ R+WDV T  
Sbjct: 445  VSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGN 502

Query: 1054 SVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVL- 1230
             +HTL+GH +  + +  +  +  +++G+ D+T+++WD+  G+   TL    K   AV   
Sbjct: 503  CIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCL 560

Query: 1231 -HPRHYTFASGSPDNIKQWKFPDGSFIQNL-----SGHNAIINTLTV-NSDGVLVSGADN 1389
               +++   S     +K W    G FI+NL      G   ++  +   N+  V   G+ N
Sbjct: 561  QFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 620

Query: 1390 GT 1395
            GT
Sbjct: 621  GT 622



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 54/166 (32%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
 Frame = +1

Query: 685  VISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 864
            V+ GH+  VRC  V+   +  V+G+ D  +K+WD  +     +L GH + V  +      
Sbjct: 426  VLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--G 481

Query: 865  PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 1044
             ++ S   D  ++ WD+E    I    GH S   G++L   I  LV+ + DST +IWD++
Sbjct: 482  IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI--LVSGNADSTVKIWDIK 539

Query: 1045 TKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGK 1179
            T   + TL G     + V C Q  +  +IT S D T++LWDL  G+
Sbjct: 540  TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGE 585


  Database: RefSeqCP
    Posted date:  Aug 1, 2006  9:25 PM
  Number of letters in database: 19,266,565
  Number of sequences in database:  33,732
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,717,499
Number of Sequences: 33732
Number of extensions: 2025975
Number of successful extensions: 9156
Number of sequences better than 1.0e-05: 10
Number of HSP's better than  0.0 without gapping: 5242
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7378
length of database: 19,266,565
effective HSP length: 110
effective length of database: 15,556,045
effective search space used: 9271402820
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

BLASTX 2.2.10 [Oct-19-2004]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AMP01_0016_F01
         (2121 letters)

Database: RefSeqSP 
           1040 sequences; 434,620 total letters

Searching...done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_999415.1| platelet-activating factor acetylhydrolase Ib-a...   127   1e-30
Alignment   gi|NP_999497.1| G-beta like protein [Sus scrofa]                      85   6e-18
Alignment   gi|NP_001012296.1| fizzy/cell division cycle 20 related 1 [Sus ...    64   1e-11

>ref|NP_999415.1| platelet-activating factor acetylhydrolase Ib-alpha subunit [Sus
            scrofa]
          Length = 410

 Score =  127 bits (319), Expect = 1e-30
 Identities = 86/323 (26%), Positives = 143/323 (44%), Gaps = 22/323 (6%)
 Frame = +1

Query: 655  QWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHIST 834
            +W P       +SGH   V  +   P     V+ S D TIK+WD  +G  + +L GH  +
Sbjct: 93   EWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS 152

Query: 835  VRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSR 1014
            V+ +        L SC  D  +K WD +  + IR  HGH   V  + + P  D +V+ +R
Sbjct: 153  VQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSAAR 212

Query: 1015 DSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTL 1194
            D T ++W+V+T   V T +GH   V  VR       I + S+D T+R+W +   + +  L
Sbjct: 213  DKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272

Query: 1195 TNHKKSVRAVVLHPR-----------HYTFASGSP----------DNIKQWKFPDGSFIQ 1311
              H+  V  +   P              T  SG P            IK W    G  + 
Sbjct: 273  REHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLM 332

Query: 1312 NLSGHNAIINTLTVNSDG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIF 1488
             L GH+  +  +  +S G  ++S AD+ T+ +WD++     + ++A         E  + 
Sbjct: 333  TLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA--------HEHFVT 384

Query: 1489 ACAFDQSESRLLTAEADKTIKVY 1557
            +  F ++   ++T   D+T+KV+
Sbjct: 385  SLDFHKTAPYVVTGSVDQTVKVW 407



 Score = 86.7 bits (213), Expect = 2e-18
 Identities = 49/183 (26%), Positives = 85/183 (46%), Gaps = 22/183 (12%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSA--DRTIKIWDLASGKLKLSLTGHISTVRGVIVS 855
            +  +GH  WVR   V+P   G +  S   D+T+++W +A+ + K  L  H   V  +  +
Sbjct: 228  KTFTGHREWVRM--VRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWA 285

Query: 856  TRS--------------------PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLD 975
              S                    P+L S   DK +K WD+     +    GH + V G+ 
Sbjct: 286  PESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVL 345

Query: 976  LHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIR 1155
             H     +++C+ D T R+WD + K  + TL+ H + V ++      P ++TGS D T++
Sbjct: 346  FHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVK 405

Query: 1156 LWD 1164
            +W+
Sbjct: 406  VWE 408



 Score = 84.0 bits (206), Expect = 1e-17
 Identities = 43/126 (34%), Positives = 70/126 (55%)
 Frame = +1

Query: 667  PWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGV 846
            P   Y  IS   G     + KPG    ++GS D+TIK+WD+++G   ++L GH + VRGV
Sbjct: 286  PESSYSSISEATGSETKKSGKPG-PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 344

Query: 847  IVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTA 1026
            +  +   ++ SC +DK ++ WD +  + ++  + H   V  LD H T   +VT S D T 
Sbjct: 345  LFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTV 404

Query: 1027 RIWDVR 1044
            ++W+ R
Sbjct: 405  KVWECR 410


>ref|NP_999497.1| G-beta like protein [Sus scrofa]
          Length = 317

 Score = 85.1 bits (209), Expect = 6e-18
 Identities = 67/252 (26%), Positives = 110/252 (43%), Gaps = 11/252 (4%)
 Frame = +1

Query: 688  ISGHLGWVRCIAVKPGNQGFV-TGSADRTIKIWDLAS-----GKLKLSLTGHISTVRGVI 849
            + GH GWV  IA  P     + + S D+TI +W L       G  + +L GH   V  V+
Sbjct: 11   LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70

Query: 850  VSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTAR 1029
            +S+   +  S   D  ++ WDL      R + GH   V  +        +V+ SRD T +
Sbjct: 71   ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130

Query: 1030 IWDVR--TKASVHTLSGHTNAVATVRC--QAAEPQIITGSHDTTIRLWDLVAGKTRVTLT 1197
            +W+     K +V   S H+  V+ VR    ++ P I++   D  +++W+L   K +    
Sbjct: 131  LWNTLGVCKYTVQDES-HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 1198 NHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLV 1374
             H   +  V + P     ASG  D     W   +G  +  L G + IIN L  + +   +
Sbjct: 190  GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD-IINALCFSPNRYWL 248

Query: 1375 SGADNGTMHLWD 1410
              A   ++ +WD
Sbjct: 249  CAATGPSIKIWD 260



 Score = 76.6 bits (187), Expect = 2e-15
 Identities = 63/262 (24%), Positives = 103/262 (39%), Gaps = 15/262 (5%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 861
            R + GH  +V  + +    Q  ++GS D T+++WDL +G       GH   V  V  S+ 
Sbjct: 57   RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116

Query: 862  SPYLFSCGEDKQVKCWD-LEYNKVIRHYHGHLSAVYGLDLHPTID--VLVTCSRDSTARI 1032
            +  + S   DK +K W+ L   K       H   V  +   P     ++V+C  D   ++
Sbjct: 117  NRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKV 176

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            W++          GHT  + TV          +G  D    LWDL  GK   TL +    
Sbjct: 177  WNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTL-DGGDI 235

Query: 1213 VRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINT-----------LTVNS 1359
            + A+   P  Y   + +  +IK W       +  L     +I+T           L  ++
Sbjct: 236  INALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELK--QEVISTSSKAEPPQCTSLAWSA 293

Query: 1360 DG-VLVSGADNGTMHLWDWRTG 1422
            DG  L +G  +  + +W    G
Sbjct: 294  DGQTLFAGYTDNLVRVWQVTIG 315


>ref|NP_001012296.1| fizzy/cell division cycle 20 related 1 [Sus scrofa]
          Length = 493

 Score = 64.3 bits (155), Expect = 1e-11
 Identities = 54/221 (24%), Positives = 96/221 (43%), Gaps = 8/221 (3%)
 Frame = +1

Query: 772  IKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVI--RHYH 945
            ++IWD A+GK    L GH  T R   ++  +  L S   D+ +   D+    +   R   
Sbjct: 253  VQIWDAAAGKKLSMLEGH--TARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSERRLQ 310

Query: 946  GHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQI 1125
            GH   V GL       +L +   D+   +W+  + + V   + H  AV  +     +  +
Sbjct: 311  GHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGL 370

Query: 1126 IT---GSHDTTIRLWDLVAGKTRVTL-TNHKKSVRAVVLHPRHYTFASG-SPDNIKQWKF 1290
            +    G+ D  IR W+ + G+    + T  +    A   H        G S + I  WK+
Sbjct: 371  LASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKY 430

Query: 1291 PDGSFIQNLSGHNAIINTLTVNSDG-VLVSGADNGTMHLWD 1410
            P  + +  L+GH+  +  L ++ DG  +V+GA + T+  W+
Sbjct: 431  PSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWN 471



 Score = 45.4 bits (106), Expect = 5e-06
 Identities = 49/197 (24%), Positives = 83/197 (42%), Gaps = 5/197 (2%)
 Frame = +1

Query: 664  PPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRG 843
            PP +  R + GH   V  +     +Q   +G  D  + +W+ +S       T H++ V+ 
Sbjct: 301  PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA 360

Query: 844  VIVSTRSPYLFSCG---EDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSR 1014
            +  S     L + G    D+ ++ W+    + ++      S V  L      + LV+   
Sbjct: 361  IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTG-SQVCNLAWSKHANELVSTHG 419

Query: 1015 DSTARI--WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRV 1188
             S  +I  W   +   V  L+GH+  V  +        I+TG+ D T+R W+ V  KTR 
Sbjct: 420  YSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWN-VFSKTRS 478

Query: 1189 TLTNHKKSVRAVVLHPR 1239
            T    K+SV  + L  R
Sbjct: 479  T----KESVSVLNLFTR 491


  Database: RefSeqSP
    Posted date:  Aug 1, 2006  7:14 PM
  Number of letters in database: 434,620
  Number of sequences in database:  1040
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,929,830
Number of Sequences: 1040
Number of extensions: 48253
Number of successful extensions: 156
Number of sequences better than 1.0e-05: 3
Number of HSP's better than  0.0 without gapping: 109
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 120
length of database: 434,620
effective HSP length: 83
effective length of database: 348,300
effective search space used: 216990900
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

BLASTX 2.2.10 [Oct-19-2004]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AMP01_0016_F01
         (2121 letters)

Database: RefSeqHP 
           39,411 sequences; 17,774,539 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_002660.1| pleiotropic regulator 1 (PRL1 homolog, Arabidop...   999   0.0  
Alignment   gi|NP_438172.1| WD repeat domain 5 [Homo sapiens]                    134   2e-31
Alignment   gi|NP_060058.1| WD repeat domain 5 [Homo sapiens]                    134   2e-31
Alignment   gi|NP_061942.2| WD repeat domain 5B [Homo sapiens]                   132   2e-30
Alignment   gi|NP_005877.2| katanin p80 subunit B 1 [Homo sapiens]               131   2e-30
Alignment   gi|NP_000421.1| platelet-activating factor acetylhydrolase, iso...   128   2e-29
Alignment   gi|NP_849143.1| hypothetical protein LOC164781 [Homo sapiens]        128   2e-29
Alignment   gi|NP_060785.2| F-box protein FBW7 isoform 2 [Homo sapiens]          125   1e-28
Alignment   gi|NP_001013433.1| F-box protein FBW7 isoform 3 [Homo sapiens]       125   1e-28
Alignment   gi|NP_361014.1| F-box protein FBW7 isoform 1 [Homo sapiens]          125   1e-28

>ref|NP_002660.1| pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) [Homo sapiens]
          Length = 514

 Score =  999 bits (2582), Expect = 0.0
 Identities = 487/515 (94%), Positives = 497/515 (96%), Gaps = 2/515 (0%)
 Frame = +1

Query: 94   MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT 273
            MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
Sbjct: 1    MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT 60

Query: 274  SKENLKEKGPQNASDSYGHKQYPANQGQEVEYLVTGTHPYPPGPGVALTPDTKIQRMPSE 453
            SKENLKEKGPQNA+DSY HKQYPANQGQEVEY V GTHPYPPGPGVALT DTKIQRMPSE
Sbjct: 61   SKENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAGTHPYPPGPGVALTADTKIQRMPSE 120

Query: 454  SAAQSLAVALPTSQARVDANRSAPAAGEYRHPGASDRSQ--SAGAVVVDGGNAKNSALMA 627
            SAAQSLAVALP  Q + DANR+AP+  EYRHPGASDR Q  +  ++V++ GN KNSALMA
Sbjct: 121  SAAQSLAVALPL-QTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMA 179

Query: 628  KKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLK 807
            KKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV+PGNQ FVTGSADRTIKIWDLASGKLK
Sbjct: 180  KKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLK 239

Query: 808  LSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPT 987
            LSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPT
Sbjct: 240  LSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPT 299

Query: 988  IDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 1167
            IDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL
Sbjct: 300  IDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 359

Query: 1168 VAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTL 1347
            VAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTL
Sbjct: 360  VAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTL 419

Query: 1348 TVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLT 1527
            TVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLT
Sbjct: 420  TVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLT 479

Query: 1528 AEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF 1632
            AEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
Sbjct: 480  AEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF 514


>ref|NP_438172.1| WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score =  134 bits (338), Expect = 2e-31
 Identities = 89/327 (27%), Positives = 158/327 (48%), Gaps = 8/327 (2%)
 Frame = +1

Query: 610  NSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDL 789
            +SA  +K  P  P       + L   ++GH   V  +   P  +   + SAD+ IKIW  
Sbjct: 21   SSATQSKPTPVKPN------YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGA 74

Query: 790  ASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYG 969
              GK + +++GH   +  V  S+ S  L S  +DK +K WD+   K ++   GH + V+ 
Sbjct: 75   YDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFC 134

Query: 970  LDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTT 1149
             + +P  +++V+ S D + RIWDV+T   + TL  H++ V+ V        I++ S+D  
Sbjct: 135  CNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGL 194

Query: 1150 IRLWDLVAGKTRVTL-TNHKKSVRAVVLHPR-HYTFASGSPDNIKQWKFPDGSFIQNLSG 1323
             R+WD  +G+   TL  +    V  V   P   Y  A+   + +K W +  G  ++  +G
Sbjct: 195  CRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTG 254

Query: 1324 HN----AIINTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFA 1491
            H      I    +V     +VSG+++  +++W+ +T    Q++      G  D    + +
Sbjct: 255  HKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ-----GHTDV---VIS 306

Query: 1492 CAFDQSESRLLTA--EADKTIKVYRED 1566
             A   +E+ + +A  E DKTIK+++ D
Sbjct: 307  TACHPTENIIASAALENDKTIKLWKSD 333


>ref|NP_060058.1| WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score =  134 bits (338), Expect = 2e-31
 Identities = 89/327 (27%), Positives = 158/327 (48%), Gaps = 8/327 (2%)
 Frame = +1

Query: 610  NSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDL 789
            +SA  +K  P  P       + L   ++GH   V  +   P  +   + SAD+ IKIW  
Sbjct: 21   SSATQSKPTPVKPN------YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGA 74

Query: 790  ASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYG 969
              GK + +++GH   +  V  S+ S  L S  +DK +K WD+   K ++   GH + V+ 
Sbjct: 75   YDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFC 134

Query: 970  LDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTT 1149
             + +P  +++V+ S D + RIWDV+T   + TL  H++ V+ V        I++ S+D  
Sbjct: 135  CNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGL 194

Query: 1150 IRLWDLVAGKTRVTL-TNHKKSVRAVVLHPR-HYTFASGSPDNIKQWKFPDGSFIQNLSG 1323
             R+WD  +G+   TL  +    V  V   P   Y  A+   + +K W +  G  ++  +G
Sbjct: 195  CRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTG 254

Query: 1324 HN----AIINTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFA 1491
            H      I    +V     +VSG+++  +++W+ +T    Q++      G  D    + +
Sbjct: 255  HKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ-----GHTDV---VIS 306

Query: 1492 CAFDQSESRLLTA--EADKTIKVYRED 1566
             A   +E+ + +A  E DKTIK+++ D
Sbjct: 307  TACHPTENIIASAALENDKTIKLWKSD 333


>ref|NP_061942.2| WD repeat domain 5B [Homo sapiens]
          Length = 330

 Score =  132 bits (331), Expect = 2e-30
 Identities = 88/327 (26%), Positives = 158/327 (48%), Gaps = 8/327 (2%)
 Frame = +1

Query: 601  NAKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKI 780
            +AK    ++  A    +   +P + L   + GH   V  +   P  +   + SADR I I
Sbjct: 8    DAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIII 67

Query: 781  WDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSA 960
            W    GK + +L GH   +  V  S+ S  L S  +DK +K WD+   K ++   GH + 
Sbjct: 68   WGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNY 127

Query: 961  VYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSH 1140
            V+  + +P  +++++ S D T +IW+V+T   + TLS H++ V+ V    +   I++GS+
Sbjct: 128  VFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSY 187

Query: 1141 DTTIRLWDLVAGKTRVTLT-NHKKSVRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQN 1314
            D   R+WD  +G+   TL  +    V  V   P      + + DN +K W +  G  ++ 
Sbjct: 188  DGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKT 247

Query: 1315 LSGHN----AIINTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESG 1482
             +GH      I    +V     +VSG+++  +++W+ +T    Q++      G  D    
Sbjct: 248  YTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ-----GHTDV--- 299

Query: 1483 IFACAFDQSESRLLTA--EADKTIKVY 1557
            + + A   +E+ + +A  E DKTIK++
Sbjct: 300  VISAACHPTENLIASAALENDKTIKLW 326


>ref|NP_005877.2| katanin p80 subunit B 1 [Homo sapiens]
          Length = 655

 Score =  131 bits (330), Expect = 2e-30
 Identities = 68/249 (27%), Positives = 114/249 (45%), Gaps = 1/249 (0%)
 Frame = +1

Query: 670  WKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVI 849
            WKL  +++        +  K   +   TG  D  + +W +      +SLTGH S V  V 
Sbjct: 11   WKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVR 70

Query: 850  VSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTAR 1029
            ++T    + +  +   ++ WDLE  K++R   GH + +  LD HP  + + + S+D+  +
Sbjct: 71   LNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIK 130

Query: 1030 IWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKK 1209
            +WD+R K  V    GH+ AV  +R       + + + D T++LWDL AGK       H  
Sbjct: 131  LWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTG 190

Query: 1210 SVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGAD 1386
             V  V  HP  Y  ASGS D  I+ W       +  + G    + ++  N DG  +    
Sbjct: 191  PVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGC 250

Query: 1387 NGTMHLWDW 1413
              ++ ++ W
Sbjct: 251  QDSLRVYGW 259


>ref|NP_000421.1| platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit
            (45kD) [Homo sapiens]
          Length = 410

 Score =  128 bits (322), Expect = 2e-29
 Identities = 87/323 (26%), Positives = 143/323 (44%), Gaps = 22/323 (6%)
 Frame = +1

Query: 655  QWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHIST 834
            +W P       +SGH   V  +   P     V+ S D TIK+WD  +G  + +L GH  +
Sbjct: 93   EWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS 152

Query: 835  VRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSR 1014
            V+ +        L SC  D  +K WD +  + IR  HGH   V  + + P  D +V+ SR
Sbjct: 153  VQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASR 212

Query: 1015 DSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTL 1194
            D T ++W+V+T   V T +GH   V  VR       I + S+D T+R+W +   + +  L
Sbjct: 213  DKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272

Query: 1195 TNHKKSVRAVVLHPR-----------HYTFASGSP----------DNIKQWKFPDGSFIQ 1311
              H+  V  +   P              T  SG P            IK W    G  + 
Sbjct: 273  REHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLM 332

Query: 1312 NLSGHNAIINTLTVNSDG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIF 1488
             L GH+  +  +  +S G  ++S AD+ T+ +WD++     + ++A         E  + 
Sbjct: 333  TLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA--------HEHFVT 384

Query: 1489 ACAFDQSESRLLTAEADKTIKVY 1557
            +  F ++   ++T   D+T+KV+
Sbjct: 385  SLDFHKTAPYVVTGSVDQTVKVW 407



 Score = 86.7 bits (213), Expect = 7e-17
 Identities = 49/183 (26%), Positives = 85/183 (46%), Gaps = 22/183 (12%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSA--DRTIKIWDLASGKLKLSLTGHISTVRGVIVS 855
            +  +GH  WVR   V+P   G +  S   D+T+++W +A+ + K  L  H   V  +  +
Sbjct: 228  KTFTGHREWVRM--VRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWA 285

Query: 856  TRS--------------------PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLD 975
              S                    P+L S   DK +K WD+     +    GH + V G+ 
Sbjct: 286  PESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVL 345

Query: 976  LHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIR 1155
             H     +++C+ D T R+WD + K  + TL+ H + V ++      P ++TGS D T++
Sbjct: 346  FHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVK 405

Query: 1156 LWD 1164
            +W+
Sbjct: 406  VWE 408



 Score = 84.0 bits (206), Expect = 5e-16
 Identities = 43/126 (34%), Positives = 70/126 (55%)
 Frame = +1

Query: 667  PWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGV 846
            P   Y  IS   G     + KPG    ++GS D+TIK+WD+++G   ++L GH + VRGV
Sbjct: 286  PESSYSSISEATGSETKKSGKPG-PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 344

Query: 847  IVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTA 1026
            +  +   ++ SC +DK ++ WD +  + ++  + H   V  LD H T   +VT S D T 
Sbjct: 345  LFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTV 404

Query: 1027 RIWDVR 1044
            ++W+ R
Sbjct: 405  KVWECR 410


>ref|NP_849143.1| hypothetical protein LOC164781 [Homo sapiens]
          Length = 415

 Score =  128 bits (321), Expect = 2e-29
 Identities = 90/342 (26%), Positives = 156/342 (45%), Gaps = 47/342 (13%)
 Frame = +1

Query: 676  LYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVS 855
            L++V+  H+  +  +A+      F+TGS DRT K+WD ASG+   +L GH + V    ++
Sbjct: 84   LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVV--YAIA 141

Query: 856  TRSPY---LFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTA 1026
              +PY   + +   DK  K W +E  K    + GH + +  L  +P   ++ T S D+TA
Sbjct: 142  FNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTA 201

Query: 1027 RIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHK 1206
            ++WD++    V+TL GH+  + ++    +  +IITGS D T+ +WD   G+    L  H 
Sbjct: 202  KLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHC 261

Query: 1207 KSVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGH-NAIINT---------LTV 1353
              + +   +       +GS D   K W   +G  +  L+GH + I+++          T 
Sbjct: 262  AEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATA 321

Query: 1354 NSDGV---------------------------------LVSGADNGTMHLWDWRTGYNFQ 1434
            ++DG                                  L++G+ + T  +WD +TG   Q
Sbjct: 322  SADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQ 381

Query: 1435 RVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVYR 1560
                 V  G  D    IF+CAF+   + ++T   D T +++R
Sbjct: 382  -----VLEGHTDE---IFSCAFNYKGNIVITGSKDNTCRIWR 415



 Score =  105 bits (263), Expect = 1e-22
 Identities = 61/247 (24%), Positives = 108/247 (43%), Gaps = 2/247 (0%)
 Frame = +1

Query: 673  KLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 852
            K Y    GH   + C++  P +    TGS D T K+WD+ +G+   +L GH + +  +  
Sbjct: 168  KCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSF 227

Query: 853  STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
            +T    + +   D  V  WD +  + +    GH + +     +    +++T S D T ++
Sbjct: 228  NTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKL 287

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD      V TL+GH + +           I T S D T R++     K    L  H+  
Sbjct: 288  WDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGE 347

Query: 1213 VRAVVLHPRHYTFASGSPDNIKQ-WKFPDGSFIQNLSGHNAIINTLTVNSDG-VLVSGAD 1386
            +  +  +P+     +GS D   + W    G  +Q L GH   I +   N  G ++++G+ 
Sbjct: 348  ISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSK 407

Query: 1387 NGTMHLW 1407
            + T  +W
Sbjct: 408  DNTCRIW 414


>ref|NP_060785.2| F-box protein FBW7 isoform 2 [Homo sapiens]
          Length = 627

 Score =  125 bits (314), Expect = 1e-28
 Identities = 89/294 (30%), Positives = 147/294 (50%), Gaps = 2/294 (0%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 861
            +V+ GH   V       GN+  V+GS D T+K+W   +GK   +L GH   V       R
Sbjct: 294  KVLKGHDDHVITCLQFCGNR-IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSS--QMR 350

Query: 862  SPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDV 1041
               + S   D+ +K W+ E  + I   +GH S V  + LH     +V+ SRD+T R+WD+
Sbjct: 351  DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDI 408

Query: 1042 RTKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVR 1218
             T   +H L GH   VA VRC Q    ++++G++D  +++WD        TL  H   V 
Sbjct: 409  ETGQCLHVLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 465

Query: 1219 AVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGT 1395
            ++     H    SGS D +I+ W    G+ I  L+GH ++ + + +  D +LVSG  + T
Sbjct: 466  SLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL-KDNILVSGNADST 522

Query: 1396 MHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 1557
            + +WD +TG   Q +      G    +S +    F  +++ ++T+  D T+K++
Sbjct: 523  VKIWDIKTGQCLQTLQ-----GPNKHQSAVTCLQF--NKNFVITSSDDGTVKLW 569



 Score =  124 bits (310), Expect = 4e-28
 Identities = 79/254 (31%), Positives = 134/254 (52%), Gaps = 4/254 (1%)
 Frame = +1

Query: 673  KLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 852
            K  R + GH G V    ++  +   ++GS DRT+K+W+  +G+   +L GH STVR + +
Sbjct: 332  KCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 389

Query: 853  STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
              +   + S   D  ++ WD+E  + +    GH++AV  +        +V+ + D   ++
Sbjct: 390  HEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKV 445

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD  T+  +HTL GHTN V +++       +++GS DT+IR+WD+  G    TLT H+  
Sbjct: 446  WDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSL 503

Query: 1213 VRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSG---HNAIINTLTVNSDGVLVSG 1380
               + L  +     SG+ D+ +K W    G  +Q L G   H + +  L  N + V+ S 
Sbjct: 504  TSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS- 560

Query: 1381 ADNGTMHLWDWRTG 1422
            +D+GT+ LWD +TG
Sbjct: 561  SDDGTVKLWDLKTG 574



 Score =  108 bits (269), Expect = 2e-23
 Identities = 71/242 (29%), Positives = 118/242 (48%), Gaps = 8/242 (3%)
 Frame = +1

Query: 694  GHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 873
            GH   VRC+ +    +  V+GS D T+++WD+ +G+    L GH++ VR V    R   +
Sbjct: 379  GHTSTVRCMHLH--EKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--V 434

Query: 874  FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKA 1053
             S   D  VK WD E    +    GH + VY L        +V+ S D++ R+WDV T  
Sbjct: 435  VSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGN 492

Query: 1054 SVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVL- 1230
             +HTL+GH +  + +  +  +  +++G+ D+T+++WD+  G+   TL    K   AV   
Sbjct: 493  CIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCL 550

Query: 1231 -HPRHYTFASGSPDNIKQWKFPDGSFIQNL-----SGHNAIINTLTV-NSDGVLVSGADN 1389
               +++   S     +K W    G FI+NL      G   ++  +   N+  V   G+ N
Sbjct: 551  QFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 610

Query: 1390 GT 1395
            GT
Sbjct: 611  GT 612



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 54/166 (32%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
 Frame = +1

Query: 685  VISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 864
            V+ GH+  VRC  V+   +  V+G+ D  +K+WD  +     +L GH + V  +      
Sbjct: 416  VLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--G 471

Query: 865  PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 1044
             ++ S   D  ++ WD+E    I    GH S   G++L   I  LV+ + DST +IWD++
Sbjct: 472  IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI--LVSGNADSTVKIWDIK 529

Query: 1045 TKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGK 1179
            T   + TL G     + V C Q  +  +IT S D T++LWDL  G+
Sbjct: 530  TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGE 575


>ref|NP_001013433.1| F-box protein FBW7 isoform 3 [Homo sapiens]
          Length = 589

 Score =  125 bits (314), Expect = 1e-28
 Identities = 89/294 (30%), Positives = 147/294 (50%), Gaps = 2/294 (0%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 861
            +V+ GH   V       GN+  V+GS D T+K+W   +GK   +L GH   V       R
Sbjct: 256  KVLKGHDDHVITCLQFCGNR-IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSS--QMR 312

Query: 862  SPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDV 1041
               + S   D+ +K W+ E  + I   +GH S V  + LH     +V+ SRD+T R+WD+
Sbjct: 313  DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDI 370

Query: 1042 RTKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVR 1218
             T   +H L GH   VA VRC Q    ++++G++D  +++WD        TL  H   V 
Sbjct: 371  ETGQCLHVLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 427

Query: 1219 AVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGT 1395
            ++     H    SGS D +I+ W    G+ I  L+GH ++ + + +  D +LVSG  + T
Sbjct: 428  SLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL-KDNILVSGNADST 484

Query: 1396 MHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 1557
            + +WD +TG   Q +      G    +S +    F  +++ ++T+  D T+K++
Sbjct: 485  VKIWDIKTGQCLQTLQ-----GPNKHQSAVTCLQF--NKNFVITSSDDGTVKLW 531



 Score =  124 bits (310), Expect = 4e-28
 Identities = 79/254 (31%), Positives = 134/254 (52%), Gaps = 4/254 (1%)
 Frame = +1

Query: 673  KLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 852
            K  R + GH G V    ++  +   ++GS DRT+K+W+  +G+   +L GH STVR + +
Sbjct: 294  KCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 351

Query: 853  STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
              +   + S   D  ++ WD+E  + +    GH++AV  +        +V+ + D   ++
Sbjct: 352  HEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKV 407

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD  T+  +HTL GHTN V +++       +++GS DT+IR+WD+  G    TLT H+  
Sbjct: 408  WDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSL 465

Query: 1213 VRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSG---HNAIINTLTVNSDGVLVSG 1380
               + L  +     SG+ D+ +K W    G  +Q L G   H + +  L  N + V+ S 
Sbjct: 466  TSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS- 522

Query: 1381 ADNGTMHLWDWRTG 1422
            +D+GT+ LWD +TG
Sbjct: 523  SDDGTVKLWDLKTG 536



 Score =  108 bits (269), Expect = 2e-23
 Identities = 71/242 (29%), Positives = 118/242 (48%), Gaps = 8/242 (3%)
 Frame = +1

Query: 694  GHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 873
            GH   VRC+ +    +  V+GS D T+++WD+ +G+    L GH++ VR V    R   +
Sbjct: 341  GHTSTVRCMHLH--EKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--V 396

Query: 874  FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKA 1053
             S   D  VK WD E    +    GH + VY L        +V+ S D++ R+WDV T  
Sbjct: 397  VSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGN 454

Query: 1054 SVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVL- 1230
             +HTL+GH +  + +  +  +  +++G+ D+T+++WD+  G+   TL    K   AV   
Sbjct: 455  CIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCL 512

Query: 1231 -HPRHYTFASGSPDNIKQWKFPDGSFIQNL-----SGHNAIINTLTV-NSDGVLVSGADN 1389
               +++   S     +K W    G FI+NL      G   ++  +   N+  V   G+ N
Sbjct: 513  QFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 572

Query: 1390 GT 1395
            GT
Sbjct: 573  GT 574



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 54/166 (32%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
 Frame = +1

Query: 685  VISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 864
            V+ GH+  VRC  V+   +  V+G+ D  +K+WD  +     +L GH + V  +      
Sbjct: 378  VLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--G 433

Query: 865  PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 1044
             ++ S   D  ++ WD+E    I    GH S   G++L   I  LV+ + DST +IWD++
Sbjct: 434  IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI--LVSGNADSTVKIWDIK 491

Query: 1045 TKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGK 1179
            T   + TL G     + V C Q  +  +IT S D T++LWDL  G+
Sbjct: 492  TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGE 537


>ref|NP_361014.1| F-box protein FBW7 isoform 1 [Homo sapiens]
          Length = 707

 Score =  125 bits (314), Expect = 1e-28
 Identities = 89/294 (30%), Positives = 147/294 (50%), Gaps = 2/294 (0%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 861
            +V+ GH   V       GN+  V+GS D T+K+W   +GK   +L GH   V       R
Sbjct: 374  KVLKGHDDHVITCLQFCGNR-IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSS--QMR 430

Query: 862  SPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDV 1041
               + S   D+ +K W+ E  + I   +GH S V  + LH     +V+ SRD+T R+WD+
Sbjct: 431  DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDI 488

Query: 1042 RTKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVR 1218
             T   +H L GH   VA VRC Q    ++++G++D  +++WD        TL  H   V 
Sbjct: 489  ETGQCLHVLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 545

Query: 1219 AVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGT 1395
            ++     H    SGS D +I+ W    G+ I  L+GH ++ + + +  D +LVSG  + T
Sbjct: 546  SLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL-KDNILVSGNADST 602

Query: 1396 MHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 1557
            + +WD +TG   Q +      G    +S +    F  +++ ++T+  D T+K++
Sbjct: 603  VKIWDIKTGQCLQTLQ-----GPNKHQSAVTCLQF--NKNFVITSSDDGTVKLW 649



 Score =  124 bits (310), Expect = 4e-28
 Identities = 79/254 (31%), Positives = 134/254 (52%), Gaps = 4/254 (1%)
 Frame = +1

Query: 673  KLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 852
            K  R + GH G V    ++  +   ++GS DRT+K+W+  +G+   +L GH STVR + +
Sbjct: 412  KCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 469

Query: 853  STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
              +   + S   D  ++ WD+E  + +    GH++AV  +        +V+ + D   ++
Sbjct: 470  HEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKV 525

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD  T+  +HTL GHTN V +++       +++GS DT+IR+WD+  G    TLT H+  
Sbjct: 526  WDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSL 583

Query: 1213 VRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSG---HNAIINTLTVNSDGVLVSG 1380
               + L  +     SG+ D+ +K W    G  +Q L G   H + +  L  N + V+ S 
Sbjct: 584  TSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS- 640

Query: 1381 ADNGTMHLWDWRTG 1422
            +D+GT+ LWD +TG
Sbjct: 641  SDDGTVKLWDLKTG 654



 Score =  108 bits (269), Expect = 2e-23
 Identities = 71/242 (29%), Positives = 118/242 (48%), Gaps = 8/242 (3%)
 Frame = +1

Query: 694  GHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 873
            GH   VRC+ +    +  V+GS D T+++WD+ +G+    L GH++ VR V    R   +
Sbjct: 459  GHTSTVRCMHLH--EKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--V 514

Query: 874  FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKA 1053
             S   D  VK WD E    +    GH + VY L        +V+ S D++ R+WDV T  
Sbjct: 515  VSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGN 572

Query: 1054 SVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVL- 1230
             +HTL+GH +  + +  +  +  +++G+ D+T+++WD+  G+   TL    K   AV   
Sbjct: 573  CIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCL 630

Query: 1231 -HPRHYTFASGSPDNIKQWKFPDGSFIQNL-----SGHNAIINTLTV-NSDGVLVSGADN 1389
               +++   S     +K W    G FI+NL      G   ++  +   N+  V   G+ N
Sbjct: 631  QFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 690

Query: 1390 GT 1395
            GT
Sbjct: 691  GT 692



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 54/166 (32%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
 Frame = +1

Query: 685  VISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 864
            V+ GH+  VRC  V+   +  V+G+ D  +K+WD  +     +L GH + V  +      
Sbjct: 496  VLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--G 551

Query: 865  PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 1044
             ++ S   D  ++ WD+E    I    GH S   G++L   I  LV+ + DST +IWD++
Sbjct: 552  IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI--LVSGNADSTVKIWDIK 609

Query: 1045 TKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGK 1179
            T   + TL G     + V C Q  +  +IT S D T++LWDL  G+
Sbjct: 610  TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGE 655


  Database: RefSeqHP
    Posted date:  Aug 2, 2006 12:57 AM
  Number of letters in database: 17,774,539
  Number of sequences in database:  39,411
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,351,761
Number of Sequences: 39411
Number of extensions: 1984886
Number of successful extensions: 8369
Number of sequences better than 1.0e-05: 10
Number of HSP's better than  0.0 without gapping: 5233
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7074
length of database: 17,774,539
effective HSP length: 109
effective length of database: 13,478,740
effective search space used: 8046807780
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

BLASTX 2.2.10 [Oct-19-2004]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AMP01_0016_F01
         (2121 letters)

Database: RefSeqMP 
           45,328 sequences; 21,768,885 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_058064.2| pleiotropic regulator 1 [Mus musculus]               987   0.0  
Alignment   gi|NP_543124.1| WD repeat domain 5 [Mus musculus]                    134   3e-31
Alignment   gi|NP_083081.2| katanin p80 (WD40-containing) subunit B 1 [Mus ...   131   2e-30
Alignment   gi|NP_081389.1| WD repeat domain 5B [Mus musculus]                   130   5e-30
Alignment   gi|NP_038653.1| platelet-activating factor acetylhydrolase, iso...   128   2e-29
Alignment   gi|NP_536353.2| F-box and WD-40 domain protein 7, archipelago h...   125   1e-28
Alignment   gi|XP_987745.1| PREDICTED: similar to platelet-activating facto...   112   2e-24
Alignment   gi|NP_080004.1| sperm associated antigen 16 isoform 2 [Mus musc...   111   3e-24
Alignment   gi|NP_083436.2| sperm associated antigen 16 isoform 1 [Mus musc...   111   3e-24
Alignment   gi|NP_081573.1| PRP4 pre-mRNA processing factor 4 homolog [Mus ...   108   2e-23

>ref|NP_058064.2| pleiotropic regulator 1 [Mus musculus]
          Length = 513

 Score =  987 bits (2551), Expect = 0.0
 Identities = 483/514 (93%), Positives = 495/514 (96%), Gaps = 1/514 (0%)
 Frame = +1

Query: 94   MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT 273
            MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
Sbjct: 1    MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT 60

Query: 274  SKENLKEKGPQNASDSYGHKQYPANQGQEVEYLVTGTHPYPPGPGVALTPDTKIQRMPSE 453
            SKENLKEKGPQNA+DSY HKQYPANQGQ+VEYLVTGTHPYP GPGVALT DTKIQRMPSE
Sbjct: 61   SKENLKEKGPQNATDSYPHKQYPANQGQDVEYLVTGTHPYPAGPGVALTADTKIQRMPSE 120

Query: 454  SAAQSLAVALPTSQARVDANRSAPAAGEYRHPGASDRSQ-SAGAVVVDGGNAKNSALMAK 630
            SAAQSLAVALP SQ RVDANR+ PA  EYRHPGASDRSQ +A   +++ GN KNSALMAK
Sbjct: 121  SAAQSLAVALP-SQTRVDANRTGPAGSEYRHPGASDRSQPTAMNSIMETGNTKNSALMAK 179

Query: 631  KAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKL 810
            KAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV+PGNQ FVTGSADRTIKIWDLASGKLKL
Sbjct: 180  KAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKL 239

Query: 811  SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI 990
            SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPT+
Sbjct: 240  SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTL 299

Query: 991  DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV 1170
            DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV
Sbjct: 300  DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV 359

Query: 1171 AGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLT 1350
            AGKTRVTLTNHKKSVRAVVLHP  YTFASGSPDNIKQWKFPDG FIQNLSGHNAIINTL 
Sbjct: 360  AGKTRVTLTNHKKSVRAVVLHPLLYTFASGSPDNIKQWKFPDGGFIQNLSGHNAIINTLA 419

Query: 1351 VNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTA 1530
            VN+DGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFD+SESRLLTA
Sbjct: 420  VNADGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDRSESRLLTA 479

Query: 1531 EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF 1632
            EADKTIKVYRED+TATEETHPVSWKPEIIKRKRF
Sbjct: 480  EADKTIKVYREDETATEETHPVSWKPEIIKRKRF 513


>ref|NP_543124.1| WD repeat domain 5 [Mus musculus]
          Length = 334

 Score =  134 bits (338), Expect = 3e-31
 Identities = 89/327 (27%), Positives = 158/327 (48%), Gaps = 8/327 (2%)
 Frame = +1

Query: 610  NSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDL 789
            +SA  +K  P  P       + L   ++GH   V  +   P  +   + SAD+ IKIW  
Sbjct: 21   SSATQSKPTPVKPN------YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGA 74

Query: 790  ASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYG 969
              GK + +++GH   +  V  S+ S  L S  +DK +K WD+   K ++   GH + V+ 
Sbjct: 75   YDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFC 134

Query: 970  LDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTT 1149
             + +P  +++V+ S D + RIWDV+T   + TL  H++ V+ V        I++ S+D  
Sbjct: 135  CNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGL 194

Query: 1150 IRLWDLVAGKTRVTL-TNHKKSVRAVVLHPR-HYTFASGSPDNIKQWKFPDGSFIQNLSG 1323
             R+WD  +G+   TL  +    V  V   P   Y  A+   + +K W +  G  ++  +G
Sbjct: 195  CRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTG 254

Query: 1324 HN----AIINTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFA 1491
            H      I    +V     +VSG+++  +++W+ +T    Q++      G  D    + +
Sbjct: 255  HKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ-----GHTDV---VIS 306

Query: 1492 CAFDQSESRLLTA--EADKTIKVYRED 1566
             A   +E+ + +A  E DKTIK+++ D
Sbjct: 307  TACHPTENIIASAALENDKTIKLWKSD 333


>ref|NP_083081.2| katanin p80 (WD40-containing) subunit B 1 [Mus musculus]
          Length = 658

 Score =  131 bits (330), Expect = 2e-30
 Identities = 68/249 (27%), Positives = 114/249 (45%), Gaps = 1/249 (0%)
 Frame = +1

Query: 670  WKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVI 849
            WKL  +++        +  K   +   TG  D  + +W +      +SLTGH S V  V 
Sbjct: 11   WKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVR 70

Query: 850  VSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTAR 1029
            ++T    + +  +   ++ WDLE  K++R   GH + +  LD HP  + + + S+D+  +
Sbjct: 71   LNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIK 130

Query: 1030 IWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKK 1209
            +WD+R K  V    GH+ AV  +R       + + + D T++LWDL AGK       H  
Sbjct: 131  LWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTG 190

Query: 1210 SVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGAD 1386
             V  V  HP  Y  ASGS D  I+ W       +  + G    + ++  N DG  +    
Sbjct: 191  PVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGC 250

Query: 1387 NGTMHLWDW 1413
              ++ ++ W
Sbjct: 251  QDSLRVYGW 259


>ref|NP_081389.1| WD repeat domain 5B [Mus musculus]
          Length = 328

 Score =  130 bits (327), Expect = 5e-30
 Identities = 85/319 (26%), Positives = 152/319 (47%), Gaps = 8/319 (2%)
 Frame = +1

Query: 634  APTMPKPQWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLS 813
            AP   +    P + L   ++GH   +  +   P  +   + +AD  I IW    G  K +
Sbjct: 17   APRREEEPQKPNYALRLTLAGHSAAISSVKFSPNGEWLASSAADALIIIWGAYDGNCKKT 76

Query: 814  LTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTID 993
            L GH   +  V  S+ S  L S  +DK +K WD+   K ++   GH   V+  D +P  +
Sbjct: 77   LYGHSLEISDVAWSSDSSRLVSASDDKTLKVWDMRSGKCLKTLKGHSDFVFCCDFNPPSN 136

Query: 994  VLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVA 1173
            ++V+ S D + +IW+V+T   + TLS H++ ++ V        I++GS+D   R+WD  +
Sbjct: 137  LIVSGSFDESVKIWEVKTGKCLKTLSAHSDPISAVNFNCNGSLIVSGSYDGLCRIWDAAS 196

Query: 1174 GKTRVTLTNH-KKSVRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSGHN----AI 1335
            G+   TL +     V  V   P      + + DN +K W +  G  ++  +GH      +
Sbjct: 197  GQCLRTLADEGNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCL 256

Query: 1336 INTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSES 1515
              + +V     +VSG+++  +++W+ +T    QR+      G  D    + + A   +++
Sbjct: 257  FASFSVTGRKWVVSGSEDNMVYIWNLQTKEIVQRLQ-----GHTDV---VISAACHPTKN 308

Query: 1516 RLLTA--EADKTIKVYRED 1566
             + +A  E DKTIKV+  D
Sbjct: 309  IIASAALENDKTIKVWSSD 327


>ref|NP_038653.1| platelet-activating factor acetylhydrolase, isoform 1b, beta1 subunit
            [Mus musculus]
          Length = 410

 Score =  128 bits (322), Expect = 2e-29
 Identities = 87/323 (26%), Positives = 143/323 (44%), Gaps = 22/323 (6%)
 Frame = +1

Query: 655  QWHPPWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHIST 834
            +W P       +SGH   V  +   P     V+ S D TIK+WD  +G  + +L GH  +
Sbjct: 93   EWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS 152

Query: 835  VRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSR 1014
            V+ +        L SC  D  +K WD +  + IR  HGH   V  + + P  D +V+ SR
Sbjct: 153  VQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASR 212

Query: 1015 DSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTL 1194
            D T ++W+V+T   V T +GH   V  VR       I + S+D T+R+W +   + +  L
Sbjct: 213  DKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272

Query: 1195 TNHKKSVRAVVLHPR-----------HYTFASGSP----------DNIKQWKFPDGSFIQ 1311
              H+  V  +   P              T  SG P            IK W    G  + 
Sbjct: 273  REHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLM 332

Query: 1312 NLSGHNAIINTLTVNSDG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIF 1488
             L GH+  +  +  +S G  ++S AD+ T+ +WD++     + ++A         E  + 
Sbjct: 333  TLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA--------HEHFVT 384

Query: 1489 ACAFDQSESRLLTAEADKTIKVY 1557
            +  F ++   ++T   D+T+KV+
Sbjct: 385  SLDFHKTAPYVVTGSVDQTVKVW 407



 Score = 86.7 bits (213), Expect = 9e-17
 Identities = 49/183 (26%), Positives = 85/183 (46%), Gaps = 22/183 (12%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSA--DRTIKIWDLASGKLKLSLTGHISTVRGVIVS 855
            +  +GH  WVR   V+P   G +  S   D+T+++W +A+ + K  L  H   V  +  +
Sbjct: 228  KTFTGHREWVRM--VRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWA 285

Query: 856  TRS--------------------PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLD 975
              S                    P+L S   DK +K WD+     +    GH + V G+ 
Sbjct: 286  PESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVL 345

Query: 976  LHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIR 1155
             H     +++C+ D T R+WD + K  + TL+ H + V ++      P ++TGS D T++
Sbjct: 346  FHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVK 405

Query: 1156 LWD 1164
            +W+
Sbjct: 406  VWE 408



 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 43/126 (34%), Positives = 70/126 (55%)
 Frame = +1

Query: 667  PWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGV 846
            P   Y  IS   G     + KPG    ++GS D+TIK+WD+++G   ++L GH + VRGV
Sbjct: 286  PESSYSSISEATGSETKKSGKPG-PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 344

Query: 847  IVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTA 1026
            +  +   ++ SC +DK ++ WD +  + ++  + H   V  LD H T   +VT S D T 
Sbjct: 345  LFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTV 404

Query: 1027 RIWDVR 1044
            ++W+ R
Sbjct: 405  KVWECR 410


>ref|NP_536353.2| F-box and WD-40 domain protein 7, archipelago homolog [Mus musculus]
          Length = 629

 Score =  125 bits (315), Expect = 1e-28
 Identities = 89/294 (30%), Positives = 147/294 (50%), Gaps = 2/294 (0%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 861
            +V+ GH   V       GN+  V+GS D T+K+W   +GK   +L GH   V       R
Sbjct: 296  KVLKGHDDHVITCLQFCGNR-IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSS--QMR 352

Query: 862  SPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDV 1041
               + S   D+ +K W+ E  + I   +GH S V  + LH     +V+ SRD+T R+WD+
Sbjct: 353  DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDI 410

Query: 1042 RTKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVR 1218
             T   +H L GH   VA VRC Q    ++++G++D  +++WD        TL  H   V 
Sbjct: 411  ETGQCLHVLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 467

Query: 1219 AVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGT 1395
            ++     H    SGS D +I+ W    G+ I  L+GH ++ + + +  D +LVSG  + T
Sbjct: 468  SLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL-KDNILVSGNADST 524

Query: 1396 MHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 1557
            + +WD +TG   Q +      G    +S +    F  +++ ++T+  D T+K++
Sbjct: 525  VKIWDIKTGQCLQTLQ-----GPSKHQSAVTCLQF--NKNFVITSSDDGTVKLW 571



 Score =  124 bits (310), Expect = 5e-28
 Identities = 79/254 (31%), Positives = 134/254 (52%), Gaps = 4/254 (1%)
 Frame = +1

Query: 673  KLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 852
            K  R + GH G V    ++  +   ++GS DRT+K+W+  +G+   +L GH STVR + +
Sbjct: 334  KCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 391

Query: 853  STRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARI 1032
              +   + S   D  ++ WD+E  + +    GH++AV  +        +V+ + D   ++
Sbjct: 392  HEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKV 447

Query: 1033 WDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKS 1212
            WD  T+  +HTL GHTN V +++       +++GS DT+IR+WD+  G    TLT H+  
Sbjct: 448  WDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQSL 505

Query: 1213 VRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSG---HNAIINTLTVNSDGVLVSG 1380
               + L  +     SG+ D+ +K W    G  +Q L G   H + +  L  N + V+ S 
Sbjct: 506  TSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITS- 562

Query: 1381 ADNGTMHLWDWRTG 1422
            +D+GT+ LWD +TG
Sbjct: 563  SDDGTVKLWDLKTG 576



 Score =  108 bits (269), Expect = 3e-23
 Identities = 71/242 (29%), Positives = 118/242 (48%), Gaps = 8/242 (3%)
 Frame = +1

Query: 694  GHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 873
            GH   VRC+ +    +  V+GS D T+++WD+ +G+    L GH++ VR V    R   +
Sbjct: 381  GHTSTVRCMHLH--EKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--V 436

Query: 874  FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKA 1053
             S   D  VK WD E    +    GH + VY L        +V+ S D++ R+WDV T  
Sbjct: 437  VSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGN 494

Query: 1054 SVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVL- 1230
             +HTL+GH +  + +  +  +  +++G+ D+T+++WD+  G+   TL    K   AV   
Sbjct: 495  CIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCL 552

Query: 1231 -HPRHYTFASGSPDNIKQWKFPDGSFIQNL-----SGHNAIINTLTV-NSDGVLVSGADN 1389
               +++   S     +K W    G FI+NL      G   ++  +   N+  V   G+ N
Sbjct: 553  QFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 612

Query: 1390 GT 1395
            GT
Sbjct: 613  GT 614



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 54/166 (32%), Positives = 86/166 (51%), Gaps = 1/166 (0%)
 Frame = +1

Query: 685  VISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 864
            V+ GH+  VRC  V+   +  V+G+ D  +K+WD  +     +L GH + V  +      
Sbjct: 418  VLMGHVAAVRC--VQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--G 473

Query: 865  PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 1044
             ++ S   D  ++ WD+E    I    GH S   G++L   I  LV+ + DST +IWD++
Sbjct: 474  IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI--LVSGNADSTVKIWDIK 531

Query: 1045 TKASVHTLSGHTNAVATVRC-QAAEPQIITGSHDTTIRLWDLVAGK 1179
            T   + TL G +   + V C Q  +  +IT S D T++LWDL  G+
Sbjct: 532  TGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGE 577


>ref|XP_987745.1| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
            subunit [Mus musculus]
          Length = 312

 Score =  112 bits (280), Expect = 2e-24
 Identities = 74/282 (26%), Positives = 126/282 (44%), Gaps = 22/282 (7%)
 Frame = +1

Query: 778  IWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLS 957
            +WD  +G  + +L GH  +V+ +        L SC  D  +K WD +  + IR  HGH  
Sbjct: 36   VWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDH 95

Query: 958  AVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGS 1137
             V  + + P  D +V+ SRD T ++W+V+T   V T +GH   V  VR       I + S
Sbjct: 96   NVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCS 155

Query: 1138 HDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPR-----------HYTFASGSP------ 1266
            +D T+R+W +   + +  L  H+  V  +   P              T  SG P      
Sbjct: 156  NDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLS 215

Query: 1267 ----DNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDG-VLVSGADNGTMHLWDWRTGYNF 1431
                  IK W    G  +  L GH+  +  +  +S G  ++S AD+ T+ +WD++     
Sbjct: 216  GSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCM 275

Query: 1432 QRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 1557
            + ++A         E  + +  F ++   ++T   D+T+KV+
Sbjct: 276  KTLNA--------HEHFVTSLDFHKTAPYVVTGSVDQTVKVW 309



 Score =  103 bits (257), Expect = 7e-22
 Identities = 65/267 (24%), Positives = 118/267 (44%), Gaps = 22/267 (8%)
 Frame = +1

Query: 682  RVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 861
            R + GH   V+ I+     +   + SAD TIK+WD    +   ++ GH   V  V +   
Sbjct: 46   RTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPN 105

Query: 862  SPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDV 1041
              ++ S   DK +K W+++    ++ + GH   V  +  +    ++ +CS D T R+W V
Sbjct: 106  GDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVV 165

Query: 1042 RTKASVHTLSGHTNAV--------------------ATVRCQAAEPQIITGSHDTTIRLW 1161
             TK     L  H + V                     T +     P +++GS D TI++W
Sbjct: 166  ATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 225

Query: 1162 DLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAII 1338
            D+  G   +TL  H   VR V+ H       S + D  ++ W + +   ++ L+ H   +
Sbjct: 226  DVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFV 285

Query: 1339 NTLTVNSDG-VLVSGADNGTMHLWDWR 1416
             +L  +     +V+G+ + T+ +W+ R
Sbjct: 286  TSLDFHKTAPYVVTGSVDQTVKVWECR 312



 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 43/126 (34%), Positives = 70/126 (55%)
 Frame = +1

Query: 667  PWKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGV 846
            P   Y  IS   G     + KPG    ++GS D+TIK+WD+++G   ++L GH + VRGV
Sbjct: 188  PESSYSSISEATGSETKKSGKPG-PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 246

Query: 847  IVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTA 1026
            +  +   ++ SC +DK ++ WD +  + ++  + H   V  LD H T   +VT S D T 
Sbjct: 247  LFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTV 306

Query: 1027 RIWDVR 1044
            ++W+ R
Sbjct: 307  KVWECR 312


>ref|NP_080004.1| sperm associated antigen 16 isoform 2 [Mus musculus]
          Length = 310

 Score =  111 bits (277), Expect = 3e-24
 Identities = 81/298 (27%), Positives = 131/298 (43%), Gaps = 2/298 (0%)
 Frame = +1

Query: 670  WKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVI 849
            +KL  +   H   V CI + P     ++ S DR  K+  L  G + L+ +GH   + G  
Sbjct: 21   YKLNNIFRLHELPVSCIVMHPCRDYLISCSEDRLWKMVGLPQGNVLLTGSGHTDWLSGCC 80

Query: 850  VSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTAR 1029
                   L +   D  +K WDL   +      GH  AV+    H   D + + S D T++
Sbjct: 81   FHPSGSKLATSSGDSTIKLWDLNKGECTLTLEGHNHAVWSCTWHSCGDFVASASLDMTSK 140

Query: 1030 IWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKK 1209
            IWDV ++   +TL GHT++V ++        ++T S D T+ +WD   GK   +L  H  
Sbjct: 141  IWDVNSERCRYTLYGHTDSVNSIEFFPFSNILLTASADKTLSVWDARTGKCEQSLYGHMH 200

Query: 1210 SVRAVVLHPRHYTFASGSPDNI-KQWKFPDGSFIQNLSGHNAIINTLTVNSDG-VLVSGA 1383
            SV      PR +  AS     + K W F     I ++    +  N +  +  G VL   +
Sbjct: 201  SVNDATFTPRGHIIASCDARGVTKLWDFRKLIPIVSIDVGPSSGNEVNFDQSGRVLAQAS 260

Query: 1384 DNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 1557
             NG +HL D ++G    ++H  V       ES + +  F      L +  +D TI+++
Sbjct: 261  ANGIIHLLDLKSG----QIHKLV-----GHESEVHSVVFSHLGENLYSGGSDGTIRLW 309


>ref|NP_083436.2| sperm associated antigen 16 isoform 1 [Mus musculus]
          Length = 639

 Score =  111 bits (277), Expect = 3e-24
 Identities = 81/298 (27%), Positives = 131/298 (43%), Gaps = 2/298 (0%)
 Frame = +1

Query: 670  WKLYRVISGHLGWVRCIAVKPGNQGFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVI 849
            +KL  +   H   V CI + P     ++ S DR  K+  L  G + L+ +GH   + G  
Sbjct: 350  YKLNNIFRLHELPVSCIVMHPCRDYLISCSEDRLWKMVGLPQGNVLLTGSGHTDWLSGCC 409

Query: 850  VSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTAR 1029
                   L +   D  +K WDL   +      GH  AV+    H   D + + S D T++
Sbjct: 410  FHPSGSKLATSSGDSTIKLWDLNKGECTLTLEGHNHAVWSCTWHSCGDFVASASLDMTSK 469

Query: 1030 IWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKK 1209
            IWDV ++   +TL GHT++V ++        ++T S D T+ +WD   GK   +L  H  
Sbjct: 470  IWDVNSERCRYTLYGHTDSVNSIEFFPFSNILLTASADKTLSVWDARTGKCEQSLYGHMH 529

Query: 1210 SVRAVVLHPRHYTFASGSPDNI-KQWKFPDGSFIQNLSGHNAIINTLTVNSDG-VLVSGA 1383
            SV      PR +  AS     + K W F     I ++    +  N +  +  G VL   +
Sbjct: 530  SVNDATFTPRGHIIASCDARGVTKLWDFRKLIPIVSIDVGPSSGNEVNFDQSGRVLAQAS 589

Query: 1384 DNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 1557
             NG +HL D ++G    ++H  V       ES + +  F      L +  +D TI+++
Sbjct: 590  ANGIIHLLDLKSG----QIHKLV-----GHESEVHSVVFSHLGENLYSGGSDGTIRLW 638


>ref|NP_081573.1| PRP4 pre-mRNA processing factor 4 homolog [Mus musculus]
          Length = 521

 Score =  108 bits (270), Expect = 2e-23
 Identities = 74/259 (28%), Positives = 113/259 (43%), Gaps = 11/259 (4%)
 Frame = +1

Query: 664  PPWKLYRVISGHLGWVRCIAVKPGNQ--------GFVTGSADRTIKIWDLASGKLKLSLT 819
            P   L   + GH   V  I   P +            + +AD ++K+W L S +    + 
Sbjct: 260  PDCSLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEPVADIE 319

Query: 820  GHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVL 999
            GH   V  V+      +L +   D+  + WDLE  + I H  GH   VY +  H    + 
Sbjct: 320  GHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLA 379

Query: 1000 VTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGK 1179
             T   D+  R+WD+RT   +  L GH   +  +        I TGS D T ++WDL   +
Sbjct: 380  GTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR 439

Query: 1180 TRVTLTNHKKSVRAVVLHPRHYTF-ASGSPDN-IKQWKFPDGSFIQNLSGHNAIINTLTV 1353
               T+  H+  V  V   P H  F  +G+ DN  K W  P  S ++ L+GH   +  L +
Sbjct: 440  CVYTIPAHQNLVTGVKFEPIHGDFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDI 499

Query: 1354 NSDGVLVSGAD-NGTMHLW 1407
            +SDG L++    + T  LW
Sbjct: 500  SSDGQLIATCSYDRTFKLW 518



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 43/202 (21%), Positives = 78/202 (38%), Gaps = 10/202 (4%)
 Frame = +1

Query: 982  PTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAV--------ATVRCQAAEPQIITGS 1137
            P   +L T       ++W V   + +HTL GH   V        +TV     +  + + +
Sbjct: 240  PNSKMLATACWSGLCKLWSVPDCSLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCA 299

Query: 1138 HDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQN 1314
             D +++LW L + +    +  H   V  V+ HP      +   D + + W       I +
Sbjct: 300  ADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILH 359

Query: 1315 LSGHNAIINTLTVNSDGVLV-SGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFA 1491
              GH+  +  +  + DG L  +G  +    +WD RTG     +   ++         I+ 
Sbjct: 360  QEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKE--------IYG 411

Query: 1492 CAFDQSESRLLTAEADKTIKVY 1557
              F  +   + T   D T KV+
Sbjct: 412  INFSPNGYHIATGSGDNTCKVW 433


  Database: RefSeqMP
    Posted date:  Aug 2, 2006 12:58 AM
  Number of letters in database: 21,768,885
  Number of sequences in database:  45,328
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,806,010
Number of Sequences: 45328
Number of extensions: 2380907
Number of successful extensions: 10087
Number of sequences better than 1.0e-05: 10
Number of HSP's better than  0.0 without gapping: 6335
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8747
length of database: 21,768,885
effective HSP length: 111
effective length of database: 16,737,477
effective search space used: 9958798815
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)