Search to RefSeqBP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= LVRM1_0010_B03
(1797 letters)
Database: RefSeqBP
33,508 sequences; 16,112,626 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_776302.1| coagulation factor II [Bos taurus] 1023 0.0
Alignment gi|NP_776376.1| plasminogen [Bos taurus] 238 9e-63
Alignment gi|XP_592554.2| PREDICTED: similar to Hepatocyte growth factor-... 180 3e-45
Alignment gi|XP_585990.2| PREDICTED: similar to Vitamin K-dependent prote... 174 3e-43
Alignment gi|XP_613822.2| PREDICTED: similar to Coagulation factor X prec... 165 1e-40
Alignment gi|XP_581622.2| PREDICTED: similar to coagulation factor IX, pa... 159 7e-39
Alignment gi|XP_596843.2| PREDICTED: similar to transmembrane protease, s... 157 3e-38
Alignment gi|NP_001029978.1| coagulation factor VII precursor, isoform b ... 154 2e-37
Alignment gi|XP_606069.2| PREDICTED: similar to mannan-binding lectin ser... 152 8e-37
Alignment gi|XP_869909.1| PREDICTED: similar to Prostasin precursor isofo... 142 1e-33
>ref|NP_776302.1| coagulation factor II [Bos taurus]
Length = 625
Score = 1023 bits (2645), Expect = 0.0
Identities = 472/551 (85%), Positives = 512/551 (92%), Gaps = 2/551 (0%)
Frame = +1
Query: 1 YEALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQ 180
+EALES S TDAFWAKYTACES R REKL ECLEGNCAEG+GMNYRGN+SVTRSGIECQ
Sbjct: 72 FEALESLSATDAFWAKYTACESARNPREKLNECLEGNCAEGVGMNYRGNVSVTRSGIECQ 131
Query: 181 LWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGR 360
LWRSRYPHKPE+NST +PGADLRENFCRNPDGSITGPWCYTTSPT+RRE CS+PVCGQ R
Sbjct: 132 LWRSRYPHKPEINSTTHPGADLRENFCRNPDGSITGPWCYTTSPTLRREECSVPVCGQDR 191
Query: 361 VTAELIPRSGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRD 540
VT E+IPRSGGST + SP LETCVP+RGR+Y+GRLAVT+HGS CLAW S QAKALSK +D
Sbjct: 192 VTVEVIPRSGGSTTSQSPLLETCVPDRGREYRGRLAVTTHGSRCLAWSSEQAKALSKHQD 251
Query: 541 FNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEEPVDGEVGDALGENAD-- 714
FNPAVPL ENFCRNPDGD+EGAWCYVA QPGDFEYCDL+YCEEPVDG++GD LGE+ D
Sbjct: 252 FNPAVPLAENFCRNPDGDEEGAWCYVADQPGDFEYCDLNYCEEPVDGDLGDRLGEDPDPD 311
Query: 715 AAIEGRTTADDFQPFFNEKTFGAGEADCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGS 894
AAIEGRT+ D FQPFFNEKTFGAGEADCGLRPLFEK ++D+TEKELFESYIEGRIVEG
Sbjct: 312 AAIEGRTSEDHFQPFFNEKTFGAGEADCGLRPLFEKKQVQDQTEKELFESYIEGRIVEGQ 371
Query: 895 DAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGK 1074
DAE+GL+PWQVM+FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFT +DLLVRIGK
Sbjct: 372 DAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLLVRIGK 431
Query: 1075 HSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKET 1254
HSRTRYER +EKISML+KIYIHPRYNW+ENLDRDIALLKL++PI SD+IHPVC PDK+T
Sbjct: 432 HSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCLPDKQT 491
Query: 1255 ATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNM 1434
A KLL AG+KGRVTGWGN +ETWTTS +EVQPSVLQVVNLP+VER VCKASTRIRITDNM
Sbjct: 492 AAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIRITDNM 551
Query: 1435 FCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFR 1614
FCAGYKP EGKRGDACEGDSGGPFVMKSP+NNRWYQMGIVSWGEGCDRDGKYGFYTHVFR
Sbjct: 552 FCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGKYGFYTHVFR 611
Query: 1615 LKKWMQKVIDR 1647
LKKW+QKVIDR
Sbjct: 612 LKKWIQKVIDR 622
>ref|NP_776376.1| plasminogen [Bos taurus]
Length = 812
Score = 238 bits (608), Expect = 9e-63
Identities = 162/516 (31%), Positives = 229/516 (44%), Gaps = 3/516 (0%)
Frame = +1
Query: 109 NCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITG 288
+C G G +YRG S T +G +CQ W S PH+ YP A L N+CRNPD
Sbjct: 383 DCYHGNGQSYRGTSSTTITGRKCQSWSSMTPHRHLKTPENYPNAGLTMNYCRNPDAD-KS 441
Query: 289 PWCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNVSPPLETCVPERGRQYQGRLA 468
PWCYTT P VR E C++ C + T E +P + + +PP C+ G+ Y+G+ A
Sbjct: 442 PWCYTTDPRVRWEFCNLKKCSE---TPEQVPAAPQAPGVENPPEADCMIGTGKSYRGKKA 498
Query: 469 VTSHGSPCLAWGSSQAKALSK-DRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEY 645
T G PC W + + S + NP L N+CRNPDGD G WCY F+Y
Sbjct: 499 TTVAGVPCQEWAAQEPHQHSIFTPETNPQSGLERNYCRNPDGDVNGPWCYTMNPRKPFDY 558
Query: 646 CDLDYCEEPVDGEVGDALGENADAAIEGRTTADDFQPFFNEKTFGAGEADCGLRPLFEKS 825
CD+ CE DCG K
Sbjct: 559 CDVPQCE---------------------------------------SSFDCG------KP 573
Query: 826 SLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAA 1005
+E K GRIV G ++ PWQV + R S CG +LIS +WVLTAA
Sbjct: 574 KVEPKK--------CSGRIVGGCVSKPHSWPWQVSLRRSSRH--FCGGTLISPKWVLTAA 623
Query: 1006 HCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIAL 1185
HCL D + V +G H+ E+++++I + +RE DIAL
Sbjct: 624 HCL-----DNILALSFYKVILGAHNEKVREQSVQEIPVSRL--------FREPSQADIAL 670
Query: 1186 LKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQV 1365
LKL +P + + P C P ++ A + +TGWG + T+ +L+
Sbjct: 671 LKLSRPAIITKEVIPACLP---PPNYMVAARTECYITGWGETQGTF-------GEGLLKE 720
Query: 1366 VNLPIVERLVCKASTRI--RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWY 1539
+LP++E VC + + R+ CAG+ D+C+GDSGGP V +++
Sbjct: 721 AHLPVIENKVCNRNEYLDGRVKPTELCAGHLIG---GTDSCQGDSGGPLVCFE--KDKYI 775
Query: 1540 QMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKVIDR 1647
G+ SWG GC R K G Y V W+++ + R
Sbjct: 776 LQGVTSWGLGCARPNKPGVYVRVSPYVPWIEETMRR 811
Score = 134 bits (337), Expect = 2e-31
Identities = 70/197 (35%), Positives = 91/197 (46%)
Frame = +1
Query: 82 EKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFC 261
EK + LE C G G YRG + T+SG+ CQ W + PH P+ + +P A L EN+C
Sbjct: 102 EKRIYLLE--CKTGNGQTYRGTTAETKSGVTCQKWSATSPHVPKFSPEKFPLAGLEENYC 159
Query: 262 RNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNVSPPLETCVPER 441
RNPD GPWCYTT P R + C IP C + C+
Sbjct: 160 RNPDNDENGPWCYTTDPDKRYDYCDIPECE-----------------------DKCMHCS 196
Query: 442 GRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVA 621
G Y+G++A T G C AW S A P L N+CRNPDG+ WC+
Sbjct: 197 GENYEGKIAKTMSGRDCQAWDSQSPHAHGYIPSKFPNKNLKMNYCRNPDGEPR-PWCFTT 255
Query: 622 GQPGDFEYCDLDYCEEP 672
+E+CD+ C P
Sbjct: 256 DPQKRWEFCDIPRCTTP 272
Score = 132 bits (332), Expect = 9e-31
Identities = 72/191 (37%), Positives = 97/191 (50%), Gaps = 5/191 (2%)
Frame = +1
Query: 112 CAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGP 291
C +G G NY G ++VT SG CQ W + PHK +P +L EN+CRNP+G P
Sbjct: 282 CLKGTGKNYGGTVAVTESGHTCQRWSEQTPHKHNRTPENFPCKNLEENYCRNPNGE-KAP 340
Query: 292 WCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNVSPPLETCVPE-----RGRQYQ 456
WCYTT+ VR E C+IP C ++ E + V V PP +T VP+ G+ Y+
Sbjct: 341 WCYTTNSEVRWEYCTIPSCESSPLSTERM------DVPV-PPEQTPVPQDCYHGNGQSYR 393
Query: 457 GRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGD 636
G + T G C +W S K + P L N+CRNPD D + WCY
Sbjct: 394 GTSSTTITGRKCQSWSSMTPHRHLKTPENYPNAGLTMNYCRNPDAD-KSPWCYTTDPRVR 452
Query: 637 FEYCDLDYCEE 669
+E+C+L C E
Sbjct: 453 WEFCNLKKCSE 463
Score = 129 bits (323), Expect = 1e-29
Identities = 73/206 (35%), Positives = 95/206 (46%)
Frame = +1
Query: 49 YTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTM 228
YT R + EC E C G NY G I+ T SG +CQ W S+ PH +
Sbjct: 172 YTTDPDKRYDYCDIPEC-EDKCMHCSGENYEGKIAKTMSGRDCQAWDSQSPHAHGYIPSK 230
Query: 229 YPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNV 408
+P +L+ N+CRNPDG PWC+TT P R E C IP C P S G
Sbjct: 231 FPNKNLKMNYCRNPDGE-PRPWCFTTDPQKRWEFCDIPRCTTP-------PPSSG----- 277
Query: 409 SPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPD 588
P C+ G+ Y G +AVT G C W ++ + P L EN+CRNP+
Sbjct: 278 --PKYQCLKGTGKNYGGTVAVTESGHTCQRWSEQTPHKHNRTPENFPCKNLEENYCRNPN 335
Query: 589 GDQEGAWCYVAGQPGDFEYCDLDYCE 666
G ++ WCY +EYC + CE
Sbjct: 336 G-EKAPWCYTTNSEVRWEYCTIPSCE 360
Score = 82.8 bits (203), Expect = 8e-16
Identities = 36/87 (41%), Positives = 50/87 (57%), Gaps = 5/87 (5%)
Frame = +1
Query: 103 EGNCAEGLGMNYRGNISVTRSGIECQLWRSRYPHK-----PEVNSTMYPGADLRENFCRN 267
E +C G G +YRG + T +G+ CQ W ++ PH+ PE N P + L N+CRN
Sbjct: 482 EADCMIGTGKSYRGKKATTVAGVPCQEWAAQEPHQHSIFTPETN----PQSGLERNYCRN 537
Query: 268 PDGSITGPWCYTTSPTVRREACSIPVC 348
PDG + GPWCYT +P + C +P C
Sbjct: 538 PDGDVNGPWCYTMNPRKPFDYCDVPQC 564
>ref|XP_592554.2| PREDICTED: similar to Hepatocyte growth factor-like protein precursor
(Macrophage stimulatory protein) (MSP) (Macrophage
stimulating protein) [Bos taurus]
Length = 711
Score = 180 bits (457), Expect = 3e-45
Identities = 145/514 (28%), Positives = 206/514 (40%), Gaps = 3/514 (0%)
Frame = +1
Query: 109 NCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITG 288
NC G G YRG ++ T +G+ CQ W ++ PH+ Y DLRENFCRNPDGS
Sbjct: 282 NCFRGKGEGYRGTVNTTAAGVPCQRWDAQLPHQHRFAPEKYACKDLRENFCRNPDGS-EA 340
Query: 289 PWCYTTSPTVRREAC-SIPVCGQGRVTAELIPRSGGSTVNVSPPLETCVPERGRQYQGRL 465
PWC+T+ P +R C I C T +V P E C G Y+G +
Sbjct: 341 PWCFTSRPGMRMAFCYQIRRC----------------TDDVRP--EDCYHGAGELYRGSV 382
Query: 466 AVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEY 645
+ T G C W + P PL ENFCRNPDGD G WCY F+Y
Sbjct: 383 SKTRKGIRCQNWSAETPHKPQFKHTSAPHTPLEENFCRNPDGDSHGPWCYTTDPGTPFDY 442
Query: 646 CDLDYCEEPVDGEVGDALGENADAAIEGRTTADDFQPFFNEKTFGAGEADCGLRPLFEKS 825
C L C+ DD QP E CG R
Sbjct: 443 CALRRCD-------------------------DDQQPSILETAHQVLFDKCGKRV----- 472
Query: 826 SLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAA 1005
T + S + R+V G G +PW V + + Q CG SL+ ++WVLTA
Sbjct: 473 -----TRVDPLHSKL--RVVGGQP---GNSPWTVSLRNRQGQHF-CGGSLVKEQWVLTAR 521
Query: 1006 HCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIAL 1185
C + + ++ + E +++ I M K+ P + L
Sbjct: 522 QC--FSSCHMSLVGYEVWLGTLFQDPQPGEPDLQHIPM-AKMVCGPS-------GSQLVL 571
Query: 1186 LKLRKPITFSDFIHPVC-PPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQ 1362
LKL +P+ + + +C PP++ ++ G + + GWG K T +VL
Sbjct: 572 LKLERPVILNQRVALICLPPER----YVVPPGTRCEIAGWGETKGTG-------DDTVLN 620
Query: 1363 VVNLPIVERLVCKASTRIRITDNMFC-AGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWY 1539
+ L ++ C R R+ ++ C AG G ACEGD GGP + ++ W
Sbjct: 621 IALLSVISNQECNVKHRGRVRESEMCTAGLLAPVG----ACEGDYGGPLACFT--HDCWV 674
Query: 1540 QMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKVI 1641
GI+ C R + V W+ KV+
Sbjct: 675 LQGIIIPNRVCARPRWPAIFMRVSVFVDWIHKVM 708
Score = 124 bits (310), Expect = 3e-28
Identities = 73/199 (36%), Positives = 97/199 (48%), Gaps = 4/199 (2%)
Frame = +1
Query: 49 YTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTM 228
YT +VR + C E C G +YRG++ T SG ECQ W ++PH
Sbjct: 170 YTTDPAVRFQSCGIKSCREATCLWCNGEDYRGSVDSTESGRECQRWDLQHPHPHPFEPGK 229
Query: 229 YPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNV 408
+ +L +N+CRNPDGS PWCYTT P + RE C +P CG +E P +T+N
Sbjct: 230 FLDKNLDDNYCRNPDGS-ERPWCYTTDPQMEREFCDLPRCG-----SEAQPSQEATTLN- 282
Query: 409 SPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNP----AVPLVENFC 576
C +G Y+G + T+ G PC W + L F P L ENFC
Sbjct: 283 ------CFRGKGEGYRGTVNTTAAGVPCQRWDAQ----LPHQHRFAPEKYACKDLRENFC 332
Query: 577 RNPDGDQEGAWCYVAGQPG 633
RNPDG E WC+ + +PG
Sbjct: 333 RNPDG-SEAPWCFTS-RPG 349
Score = 115 bits (288), Expect = 1e-25
Identities = 65/192 (33%), Positives = 85/192 (44%), Gaps = 8/192 (4%)
Frame = +1
Query: 112 CAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGP 291
C G+ YRG +++T G+ CQ W R+P+ + T+ G L ENFCRNPD GP
Sbjct: 110 CIVDNGVEYRGTVAITVGGLPCQRWSHRFPNDHKFTPTLRNG--LEENFCRNPDRDPGGP 167
Query: 292 WCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNVSPPLETCVPERGRQYQGRLAV 471
WCYTT P VR ++C I C + TC+ G Y+G +
Sbjct: 168 WCYTTDPAVRFQSCGIKSCREA----------------------TCLWCNGEDYRGSVDS 205
Query: 472 TSHGSPCLAWGSSQ--------AKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQ 627
T G C W K L K+ D +N+CRNPDG E WCY
Sbjct: 206 TESGRECQRWDLQHPHPHPFEPGKFLDKNLD--------DNYCRNPDG-SERPWCYTTDP 256
Query: 628 PGDFEYCDLDYC 663
+ E+CDL C
Sbjct: 257 QMEREFCDLPRC 268
Score = 67.8 bits (164), Expect = 3e-11
Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Frame = +1
Query: 418 LETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVP--LVENFCRNPDG 591
+ TC+ + G +Y+G +A+T G PC W + D F P + L ENFCRNPD
Sbjct: 107 VRTCIVDNGVEYRGTVAITVGGLPCQRW----SHRFPNDHKFTPTLRNGLEENFCRNPDR 162
Query: 592 DQEGAWCYVAGQPGDFEYCDLDYCEE 669
D G WCY F+ C + C E
Sbjct: 163 DPGGPWCYTTDPAVRFQSCGIKSCRE 188
>ref|XP_585990.2| PREDICTED: similar to Vitamin K-dependent protein C precursor
(Autoprothrombin IIA) (Anticoagulant protein C) (Blood
coagulation factor XIV) [Bos taurus]
Length = 444
Score = 174 bits (440), Expect = 3e-43
Identities = 113/302 (37%), Positives = 161/302 (53%), Gaps = 1/302 (0%)
Frame = +1
Query: 727 GRTTADDFQPFFNEKTFGAGEADCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEI 906
G DD Q ++ TF G G R ++ +L+ T + + ++ RIV+G +A
Sbjct: 150 GYRLEDDHQLCVSKVTFPCGRL--GKRMEKKRKTLKRDTNQVDQKDQLDPRIVDGQEAGW 207
Query: 907 GLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRT 1086
G +PWQ ++ S ++L+CGA LI WVLT AHCL + L+VR+G++
Sbjct: 208 GESPWQAVLL-DSKKKLVCGAVLIHVSWVLTVAHCL--------DSRKKLIVRLGEYDMR 258
Query: 1087 RYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETAT-K 1263
R+E + E ++++ IHP Y + D DIALL+L KP T S I P+C PD + K
Sbjct: 259 RWE-SWEVDLDIKEVIIHPNYT-KSTSDNDIALLRLAKPATLSQTIVPICLPDSGLSERK 316
Query: 1264 LLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCA 1443
L + G + VTGWG ET + VL + +P+V C + +I++NM CA
Sbjct: 317 LTQVGQETVVTGWGYRDET-----KRNRTFVLSFIKVPVVPYNACVHAMENKISENMLCA 371
Query: 1444 GYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKK 1623
G D DACEGDSGGP V + F W+ +G+VSWGEGC R YG YT V R
Sbjct: 372 GILGDPR---DACEGDSGGPMV--TFFRGTWFLVGLVSWGEGCGRLYNYGVYTKVSRYLD 426
Query: 1624 WM 1629
W+
Sbjct: 427 WI 428
>ref|XP_613822.2| PREDICTED: similar to Coagulation factor X precursor (Stuart factor)
(Stuart-Prower factor) [Bos taurus]
Length = 585
Score = 165 bits (417), Expect = 1e-40
Identities = 101/255 (39%), Positives = 141/255 (55%)
Frame = +1
Query: 877 RIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 1056
RIV G D G PWQ ++ + E CG +++++ +VLTAAHCL K FT
Sbjct: 326 RIVGGRDCAEGECPWQALLVNEE-NEGFCGGTILNEFYVLTAAHCLHQA---KRFT---- 377
Query: 1057 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVC 1236
VR+G + + E N E +E H R+ +E D DIA+L+L+ PI F + P C
Sbjct: 378 -VRVGDRNTEQEEGN-EMAHEVEMTVKHSRFV-KETYDFDIAVLRLKTPIRFRRNVAPAC 434
Query: 1237 PPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRI 1416
P+K+ A L G V+G+G E S S L+++ +P V+R CK S+
Sbjct: 435 LPEKDWAEATLMTQKTGIVSGFGRTHEKGRLS------STLKMLEVPYVDRSTCKLSSSF 488
Query: 1417 RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGF 1596
IT NMFCAGY + + DAC+GDSGGP V + F + ++ GIVSWGEGC R GK+G
Sbjct: 489 TITPNMFCAGY---DTQPEDACQGDSGGPHVTR--FKDTYFVTGIVSWGEGCARKGKFGV 543
Query: 1597 YTHVFRLKKWMQKVI 1641
YT V KW+ K++
Sbjct: 544 YTKVSNFLKWIDKIM 558
>ref|XP_581622.2| PREDICTED: similar to coagulation factor IX, partial [Bos taurus]
Length = 432
Score = 159 bits (402), Expect = 7e-39
Identities = 97/284 (34%), Positives = 155/284 (54%), Gaps = 9/284 (3%)
Frame = +1
Query: 811 LFEKSSLEDKTEKELF--------ESYIE-GRIVEGSDAEIGLAPWQVMIFRKSPQELLC 963
+F ++ E+ +E E+ +S+ E R+V G DAE G PWQV++ + C
Sbjct: 166 IFSNTNYENSSEAEIIWDNVTQSNQSFDEFSRVVGGEDAERGQFPWQVLLHGEIAA--FC 223
Query: 964 GASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHP 1143
G S+++++WV+TAAHC+ P K + V G+H+ + E +K +++ I H
Sbjct: 224 GGSIVNEKWVVTAAHCI--KPGVK------ITVVAGEHNTEKPEPTEQKRNVIRAIPYHS 275
Query: 1144 RYNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETW 1323
DIALL+L +P+ + ++ P+C D++ L+ GY G V+GWG +
Sbjct: 276 YNASINKYSHDIALLELDEPLELNSYVTPICIADRDYTNIFLKFGY-GYVSGWGKVFNRG 334
Query: 1324 TTSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGP 1503
++ S+LQ + +P+V+R C ST+ I +MFCAGY EG + D+C+GDSGGP
Sbjct: 335 RSA------SILQYLKVPLVDRATCLRSTKFSIYSHMFCAGYH--EGGK-DSCQGDSGGP 385
Query: 1504 FVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQK 1635
V + + + GI+SWGE C GKYG YT V R W+++
Sbjct: 386 HVTEVEGTS--FLTGIISWGEECAMKGKYGIYTKVSRYVNWIKE 427
>ref|XP_596843.2| PREDICTED: similar to transmembrane protease, serine 9 [Bos taurus]
Length = 903
Score = 157 bits (397), Expect = 3e-38
Identities = 96/280 (34%), Positives = 147/280 (52%), Gaps = 1/280 (0%)
Frame = +1
Query: 793 DCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGAS 972
+CG RP EK + RIV G A +G PWQV + K CGA+
Sbjct: 657 ECGARPALEKPT----------------RIVGGLGASLGEVPWQVSL--KEGSRHFCGAT 698
Query: 973 LISDRWVLTAAHCLLYPPWDKNFTENDLL-VRIGKHSRTRYERNIEKISMLEKIYIHPRY 1149
++ DRW+L+AAHC N T+ +L+ ++G S + + K+ L ++ +HP+Y
Sbjct: 699 VVGDRWLLSAAHCF-------NHTKVELVRAQLGTASLSGVGGSPVKVG-LRRVVLHPQY 750
Query: 1150 NWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWTT 1329
N LD D+A+L+L +P+ F+ ++ PVC P A + G K ++GWGN +E
Sbjct: 751 N-PSILDFDVAVLELARPLVFNKYVQPVCLP---LAIQKFPVGRKCVISGWGNTQE---- 802
Query: 1330 SASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFV 1509
+ +P +LQ ++ I++ C A +TD M CAG+ EGK D+C+GD+GGP
Sbjct: 803 -GNATKPDLLQQASVGIIDHKACSALYNFSLTDRMICAGFL--EGKV-DSCQGDAGGPLA 858
Query: 1510 MKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWM 1629
+ P + RW G+ SWG GC R G YT V ++ W+
Sbjct: 859 CREP-SGRWVLTGVTSWGYGCGRPQFPGVYTRVAAVRGWI 897
Score = 102 bits (255), Expect = 8e-22
Identities = 75/239 (31%), Positives = 125/239 (52%), Gaps = 3/239 (1%)
Frame = +1
Query: 778 GAGEA--DCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQ 951
G+ EA DCGL+P ++ + GRIV G +A G PWQV + +
Sbjct: 381 GSDEAHCDCGLQPGWKTA----------------GRIVGGVEASPGEFPWQVSL--RENN 422
Query: 952 ELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN-DLLVRIGKHSRTRYERNIEKISMLEK 1128
E CGA++IS RW+++AAHC F ++ + + +G + E ++ + + + +
Sbjct: 423 EHFCGAAIISARWLVSAAHCF------NEFQDSPEWVAYVGTTYLSGSEASMVR-ARVAR 475
Query: 1129 IYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGN 1308
I HP YN + D D+A+L+L +P+ FS + PVC P A+ + K ++GWG
Sbjct: 476 IITHPSYN-SDTADFDVAVLELGRPLPFSRHVQPVCLP---AASHIFPPRKKCLISGWGY 531
Query: 1309 LKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACE 1485
LKE + V+P +LQ + ++++ +C + +TD M CAGY +GK D+C+
Sbjct: 532 LKENFL-----VKPEMLQKATVELLDQALCTSLYGHSLTDRMVCAGYL--DGK-VDSCQ 582
>ref|NP_001029978.1| coagulation factor VII precursor, isoform b [Bos taurus]
Length = 447
Score = 154 bits (390), Expect = 2e-37
Identities = 100/290 (34%), Positives = 147/290 (50%), Gaps = 5/290 (1%)
Frame = +1
Query: 787 EADCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCG 966
E CG P+ EK + S +GRIV G G PWQ M+ K LLCG
Sbjct: 172 EYPCGKIPVLEKRN----------GSKPQGRIVGGHVCPKGECPWQAML--KLNGALLCG 219
Query: 967 ASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPR 1146
+L+ WV++AAHC +++ + +L +G+H +R E ++ + + I P+
Sbjct: 220 GTLVGPAWVVSAAHC-----FERLRSRGNLTAVLGEHDLSRVEGPEQERRVAQIIV--PK 272
Query: 1147 YNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWT 1326
D D+ALL+L +P+ D + P+C PD + A + L V+GWG L E
Sbjct: 273 QYVPGQTDHDVALLQLAQPVALGDHVAPLCLPDPDFADQTLAFVRFSAVSGWGQLLERGV 332
Query: 1327 TSASEVQPSVLQVVNLPIVERLVCKASTRIR-----ITDNMFCAGYKPDEGKRGDACEGD 1491
T+ L VV +P + C +R R +TDNMFCAGY +G + DAC+GD
Sbjct: 333 TARK------LMVVLVPRLLTQDCLQQSRQRPGGPVVTDNMFCAGYS--DGSK-DACKGD 383
Query: 1492 SGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKVI 1641
SGGP + F W+ G+VSWGEGC G +G YT V R W+++++
Sbjct: 384 SGGPHATR--FRGTWFLTGVVSWGEGCAAAGHFGIYTRVSRYTAWLRQLM 431
>ref|XP_606069.2| PREDICTED: similar to mannan-binding lectin serine protease 1 isoform
1 precursor [Bos taurus]
Length = 395
Score = 152 bits (384), Expect = 8e-37
Identities = 91/272 (33%), Positives = 141/272 (51%), Gaps = 11/272 (4%)
Frame = +1
Query: 856 FESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDK 1035
F + RI+ G A+ G PW M+ + Q CG SL+ +W++TAAHCL P +
Sbjct: 137 FSRNLLARIINGRPAQKGTTPWIAMLSHLNGQPF-CGGSLLGSKWIVTAAHCLHEAPDSE 195
Query: 1036 NFTENDL--------LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLK 1191
+ T DL + +GK RT+ + N E+ +++++ HP YN + D+ALL+
Sbjct: 196 DVTLRDLDLLSPSAFKIIMGKLRRTQSDEN-EQSLRVKQVFFHPLYN-PNTYENDVALLE 253
Query: 1192 LRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVN 1371
L + +DF+ P+C P + G V+GWG + P L +
Sbjct: 254 LSRGPVLNDFVMPICLPQRPP-----EEGAVVIVSGWGK-------QFLQRFPETLMEIE 301
Query: 1372 LPIVERLVCK---ASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQ 1542
+PIV+ +C+ A + ++T +M CAG K EG R DAC GDSGGP V +WY
Sbjct: 302 IPIVDYHICREAYAPLKKKVTRDMICAGEK--EGGR-DACAGDSGGPMVTLDTQRGQWYL 358
Query: 1543 MGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKV 1638
+G VSWG C + +YG Y+++F K W+++V
Sbjct: 359 VGTVSWGVDCGKKDRYGVYSYIFHNKDWIRRV 390
>ref|XP_869909.1| PREDICTED: similar to Prostasin precursor isoform 2 [Bos taurus]
Length = 342
Score = 142 bits (357), Expect = 1e-33
Identities = 92/261 (35%), Positives = 131/261 (50%), Gaps = 8/261 (3%)
Frame = +1
Query: 871 EGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 1050
+GRI G+ A +G PWQV I +CG SL+SD+WVL+AAHC P D E
Sbjct: 42 QGRITGGTTAALGQWPWQVSINHHGTH--VCGGSLVSDQWVLSAAHCF---PSDNKIEEY 96
Query: 1051 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHP 1230
+ V++G H + + + + + ++ H +Y+ ++ DIALL+L +TFS +I P
Sbjct: 97 E--VKLGAHQLDYFSTDTQ-VRGVAQVISHEKYSHEGSMG-DIALLQLSSSVTFSRYIRP 152
Query: 1231 VCPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKAST 1410
+C P A G + VTGWG++ S S P LQ + +P++ R C
Sbjct: 153 ICLP---AANASFPNGLQCVVTGWGHV----APSVSLQHPRPLQQLEVPLISRETCNCLY 205
Query: 1411 RIR--------ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE 1566
I I +M CAGY G + DAC+GDSGGP + P RWY GIVSWG+
Sbjct: 206 NINAKPGEPHVIDQDMLCAGYV--NGSK-DACQGDSGGP--LSCPVAGRWYLAGIVSWGD 260
Query: 1567 GCDRDGKYGFYTHVFRLKKWM 1629
C + G YT W+
Sbjct: 261 ACGAPNRPGVYTLTSVYASWI 281
Database: RefSeqBP
Posted date: Aug 1, 2006 7:14 PM
Number of letters in database: 16,112,626
Number of sequences in database: 33,508
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,958,974
Number of Sequences: 33508
Number of extensions: 2117260
Number of successful extensions: 9657
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 6679
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9165
length of database: 16,112,626
effective HSP length: 107
effective length of database: 12,527,270
effective search space used: 6150889570
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqCP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= LVRM1_0010_B03
(1797 letters)
Database: RefSeqCP
33,732 sequences; 19,266,565 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|XP_533468.2| PREDICTED: similar to Plasminogen precursor [Ca... 201 1e-51
Alignment gi|XP_855946.1| PREDICTED: similar to Coagulation factor X prec... 172 7e-43
Alignment gi|XP_534191.1| PREDICTED: similar to Coagulation factor X prec... 172 1e-42
Alignment gi|NP_001013871.1| protein C (inactivator of coagulation factor... 168 2e-41
Alignment gi|XP_855987.1| PREDICTED: similar to Coagulation factor X prec... 165 1e-40
Alignment gi|NP_001003323.1| coagulation factor IX [Canis familiaris] 164 3e-40
Alignment gi|XP_849513.1| PREDICTED: similar to Coagulation factor VII pr... 155 1e-37
Alignment gi|XP_531743.2| PREDICTED: similar to transmembrane protease, s... 151 2e-36
Alignment gi|XP_861032.1| PREDICTED: similar to mannan-binding lectin ser... 147 3e-35
Alignment gi|XP_850550.1| PREDICTED: similar to transmembrane protease, s... 145 1e-34
>ref|XP_533468.2| PREDICTED: similar to Plasminogen precursor [Canis familiaris]
Length = 812
Score = 201 bits (512), Expect = 1e-51
Identities = 153/569 (26%), Positives = 240/569 (42%), Gaps = 59/569 (10%)
Frame = +1
Query: 112 CAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGP 291
C +G G +YRG +SVT SG CQ W + PHK +P +L EN+CRNPDG T P
Sbjct: 275 CLKGRGESYRGKVSVTVSGHTCQHWSEQTPHKHNRTPENFPCKNLDENYCRNPDGE-TAP 333
Query: 292 WCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNVSPPLETCVPERGRQYQGRLAV 471
WCYTT+ VR E C IP C +T E + +P ++ C G+ Y+G +
Sbjct: 334 WCYTTNSEVRWEHCQIPSCESSPITTEYLDAPASVPPEQTPVVQECYHGNGQSYRGTSST 393
Query: 472 TSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCD 651
T G C +W S K + P L N+CRNPD D + WCY +E+C+
Sbjct: 394 TITGRKCQSWSSMTPHRHEKTPEHFPEAGLTMNYCRNPDAD-KSPWCYTTDPSVRWEFCN 452
Query: 652 LDYCEEPVDGEVGDALGENADAAIE---GRTTADDFQPFFNEKTFGAGEADCGLRPLFEK 822
L C +P +A N+ A + G+ + F N K + +A + ++
Sbjct: 453 LRKCLDP------EASATNSPAVPQVPSGQEPSASDCMFGNGKGYRGKKATTVMGIPCQE 506
Query: 823 SSLEDKTEKELF------ESYIEGRIVEGSDAEIGLAPW-----QVMIF----------- 936
+ ++ +F ++ +E D ++ PW Q +F
Sbjct: 507 WAAQEPHRHSIFTPETNPQAGLEKNYCRNPDGDVN-GPWCYTMNQRKLFDYCDVPQCVST 565
Query: 937 -----------RKSPQELL--CGASLISDRWVLT---------AAHCLLYPPW------- 1029
+K P ++ C A+ S W ++ L+ P W
Sbjct: 566 SFDCGKPQVEPKKCPGRVVGGCVANPHSWPWQISLRTRYGKHFCGGTLISPEWVLTAAHC 625
Query: 1030 -DKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPI 1206
+++ V +G H E ++++I + K+++ P DIALLKL P
Sbjct: 626 LERSSRPASYKVILGAHKEVNLESDVQEIEVY-KLFLEP-------TRADIALLKLSSPA 677
Query: 1207 TFSDFIHPVC--PPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPI 1380
+ + P C PP+ A + L +TGWG + T+ +L+ LP+
Sbjct: 678 VITSKVIPACLPPPNYVVADRTL-----CYITGWGETQGTYGA-------GLLKEAQLPV 725
Query: 1381 VERLVCKASTRI--RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIV 1554
+E VC + R+ CAG + D+C+GDSGGP V +++ G+
Sbjct: 726 IENKVCNRYEYLNGRVKSTELCAG---NLAGGTDSCQGDSGGPLVCFE--KDKYILQGVT 780
Query: 1555 SWGEGCDRDGKYGFYTHVFRLKKWMQKVI 1641
SWG GC R K G Y V R W++ ++
Sbjct: 781 SWGLGCARPNKPGVYVRVSRFVTWIEGIM 809
Score = 137 bits (345), Expect = 3e-32
Identities = 79/217 (36%), Positives = 103/217 (47%), Gaps = 1/217 (0%)
Frame = +1
Query: 49 YTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTM 228
YT VR + EC E C G NY G IS T+SG+ECQ W S+ PH +
Sbjct: 165 YTTNPDVRFDYCNIPEC-EEECMHCSGENYEGKISKTKSGLECQAWNSQTPHAHGYIPSK 223
Query: 229 YPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNV 408
+P +L+ N+CRNPDG PWC+T P R E C IP C P SG
Sbjct: 224 FPSKNLKMNYCRNPDGE-PRPWCFTMDPNKRWEFCDIPRC------TTPPPPSG------ 270
Query: 409 SPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPD 588
P C+ RG Y+G+++VT G C W ++ + P L EN+CRNPD
Sbjct: 271 --PTYQCLKGRGESYRGKVSVTVSGHTCQHWSEQTPHKHNRTPENFPCKNLDENYCRNPD 328
Query: 589 GDQEGAWCYVAGQPGDFEYCDLDYCE-EPVDGEVGDA 696
G + WCY +E+C + CE P+ E DA
Sbjct: 329 G-ETAPWCYTTNSEVRWEHCQIPSCESSPITTEYLDA 364
Score = 132 bits (331), Expect = 1e-30
Identities = 65/187 (34%), Positives = 87/187 (46%)
Frame = +1
Query: 112 CAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGP 291
C G G YRG ++ T++ + CQ W PHKP +P L EN+CRNPD GP
Sbjct: 103 CKTGNGKTYRGTMAKTKNDVACQKWSDNSPHKPNYTPEKHPLEGLEENYCRNPDNDENGP 162
Query: 292 WCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNVSPPLETCVPERGRQYQGRLAV 471
WCYTT+P VR + C+IP C E C+ G Y+G+++
Sbjct: 163 WCYTTNPDVRFDYCNIPECE-----------------------EECMHCSGENYEGKISK 199
Query: 472 TSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCD 651
T G C AW S A P+ L N+CRNPDG+ WC+ +E+CD
Sbjct: 200 TKSGLECQAWNSQTPHAHGYIPSKFPSKNLKMNYCRNPDGEPR-PWCFTMDPNKRWEFCD 258
Query: 652 LDYCEEP 672
+ C P
Sbjct: 259 IPRCTTP 265
Score = 78.2 bits (191), Expect = 2e-14
Identities = 36/85 (42%), Positives = 47/85 (55%), Gaps = 5/85 (5%)
Frame = +1
Query: 109 NCAEGLGMNYRGNISVTRSGIECQLWRSRYPHK-----PEVNSTMYPGADLRENFCRNPD 273
+C G G YRG + T GI CQ W ++ PH+ PE N P A L +N+CRNPD
Sbjct: 482 DCMFGNGKGYRGKKATTVMGIPCQEWAAQEPHRHSIFTPETN----PQAGLEKNYCRNPD 537
Query: 274 GSITGPWCYTTSPTVRREACSIPVC 348
G + GPWCYT + + C +P C
Sbjct: 538 GDVNGPWCYTMNQRKLFDYCDVPQC 562
Score = 70.5 bits (171), Expect = 5e-12
Identities = 34/102 (33%), Positives = 48/102 (47%)
Frame = +1
Query: 418 LETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQ 597
L C G+ Y+G +A T + C W + + + +P L EN+CRNPD D+
Sbjct: 100 LSECKTGNGKTYRGTMAKTKNDVACQKWSDNSPHKPNYTPEKHPLEGLEENYCRNPDNDE 159
Query: 598 EGAWCYVAGQPGDFEYCDLDYCEEPVDGEVGDALGENADAAI 723
G WCY F+YC++ CEE E GEN + I
Sbjct: 160 NGPWCYTTNPDVRFDYCNIPECEE----ECMHCSGENYEGKI 197
>ref|XP_855946.1| PREDICTED: similar to Coagulation factor X precursor (Stuart factor)
(Stuart-Prower factor) isoform 2 [Canis familiaris]
Length = 493
Score = 172 bits (437), Expect = 7e-43
Identities = 104/260 (40%), Positives = 141/260 (54%), Gaps = 7/260 (2%)
Frame = +1
Query: 877 RIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 1056
RIV G D G PWQ ++ + E CG +++S+ ++LTAAHCL K FT
Sbjct: 239 RIVGGQDCRDGECPWQALLINEE-NEGFCGGTILSEYYILTAAHCLQQA---KKFT---- 290
Query: 1057 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNW-------RENLDRDIALLKLRKPITFS 1215
VR+GK + E + + L IY P+Y + RE D DIA++KL+ PITF
Sbjct: 291 -VRVGKWRLSSSEMKLILVIYLHPIY--PKYYYFNHNKFVRETYDFDIAVIKLKTPITFR 347
Query: 1216 DFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLV 1395
+ P C P K+ A L G V+G+G E S + L+++ +P V+R
Sbjct: 348 MNVAPACLPQKDWAESTLMTQKTGIVSGFGKTHEKGRPSTT------LKMMEVPYVDRNT 401
Query: 1396 CKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCD 1575
CK S+ IT NMFCAGY + K DAC+GDSGGP V + F + ++ GIVSWGEGC
Sbjct: 402 CKLSSSFSITQNMFCAGY---DSKPEDACQGDSGGPHVTR--FKDTYFVTGIVSWGEGCA 456
Query: 1576 RDGKYGFYTHVFRLKKWMQK 1635
R GKYG YT V KW+ +
Sbjct: 457 RKGKYGIYTKVTNFLKWIDR 476
>ref|XP_534191.1| PREDICTED: similar to Coagulation factor X precursor (Stuart factor)
(Stuart-Prower factor) isoform 1 [Canis familiaris]
Length = 486
Score = 172 bits (435), Expect = 1e-42
Identities = 103/253 (40%), Positives = 140/253 (55%)
Frame = +1
Query: 877 RIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 1056
RIV G D G PWQ ++ + E CG +++S+ ++LTAAHCL K FT
Sbjct: 239 RIVGGQDCRDGECPWQALLINEE-NEGFCGGTILSEYYILTAAHCLQQA---KKFT---- 290
Query: 1057 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVC 1236
VR+G+ + E N E +E I H ++ RE D DIA++KL+ PITF + P C
Sbjct: 291 -VRVGERDTDKEEGN-EVAHEVEMIIKHNKFV-RETYDFDIAVIKLKTPITFRMNVAPAC 347
Query: 1237 PPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRI 1416
P K+ A L G V+G+G E S + L+++ +P V+R CK S+
Sbjct: 348 LPQKDWAESTLMTQKTGIVSGFGKTHEKGRPSTT------LKMMEVPYVDRNTCKLSSSF 401
Query: 1417 RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGF 1596
IT NMFCAGY + K DAC+GDSGGP V + F + ++ GIVSWGEGC R GKYG
Sbjct: 402 SITQNMFCAGY---DSKPEDACQGDSGGPHVTR--FKDTYFVTGIVSWGEGCARKGKYGI 456
Query: 1597 YTHVFRLKKWMQK 1635
YT V KW+ +
Sbjct: 457 YTKVTNFLKWIDR 469
>ref|NP_001013871.1| protein C (inactivator of coagulation factors Va and VIIIa) [Canis
familiaris]
Length = 456
Score = 168 bits (425), Expect = 2e-41
Identities = 102/259 (39%), Positives = 138/259 (53%), Gaps = 1/259 (0%)
Frame = +1
Query: 868 IEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 1047
I+ R+V G G +PWQV++ S ++L CGA LI WVLTAAHC+
Sbjct: 207 IDPRLVNGKVTRRGESPWQVVLL-DSKKKLACGAVLIHTSWVLTAAHCME--------DS 257
Query: 1048 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIH 1227
L+VR+G++ R+E+ + + E + IHP Y+ + D DIALL L +P FS I
Sbjct: 258 KKLIVRLGEYDLRRWEKGEMDVDIKE-VLIHPNYS-KSTTDNDIALLHLAQPAIFSQTIV 315
Query: 1228 PVCPPDKETATK-LLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKA 1404
P+C PD A + L + G + VTGWG ET + VL +N+P+ C
Sbjct: 316 PICLPDSGLAERELTQVGQETVVTGWGYRSET-----KRNRTFVLNFINIPVAPHNECIQ 370
Query: 1405 STRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDG 1584
+ I++NM CAG D DACEGDSGGP V + F W+ +G+VSWGEGC R
Sbjct: 371 AMYNMISENMLCAGILGDSR---DACEGDSGGPMV--TSFRGTWFLVGLVSWGEGCGRLH 425
Query: 1585 KYGFYTHVFRLKKWMQKVI 1641
YG YT V R W+ I
Sbjct: 426 NYGIYTKVSRYLDWIHSHI 444
>ref|XP_855987.1| PREDICTED: similar to Coagulation factor X precursor (Stuart factor)
(Stuart-Prower factor) isoform 3 [Canis familiaris]
Length = 492
Score = 165 bits (418), Expect = 1e-40
Identities = 103/260 (39%), Positives = 141/260 (54%), Gaps = 7/260 (2%)
Frame = +1
Query: 877 RIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 1056
RIV G D G PWQ ++ + E CG +++S+ ++LTAAHCL K FT
Sbjct: 239 RIVGGQDCRDGECPWQALLINEE-NEGFCGGTILSEYYILTAAHCLQQA---KKFT---- 290
Query: 1057 LVRIGKHSRTRYERNIEKISMLEKIYI-------HPRYNWRENLDRDIALLKLRKPITFS 1215
VR+GK + + NI KI + + H ++ RE D DIA++KL+ PITF
Sbjct: 291 -VRVGKCNIS--SSNISKILLFQCFMPAAVGSEQHNKFV-RETYDFDIAVIKLKTPITFR 346
Query: 1216 DFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLV 1395
+ P C P K+ A L G V+G+G E S + L+++ +P V+R
Sbjct: 347 MNVAPACLPQKDWAESTLMTQKTGIVSGFGKTHEKGRPSTT------LKMMEVPYVDRNT 400
Query: 1396 CKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCD 1575
CK S+ IT NMFCAGY + K DAC+GDSGGP V + F + ++ GIVSWGEGC
Sbjct: 401 CKLSSSFSITQNMFCAGY---DSKPEDACQGDSGGPHVTR--FKDTYFVTGIVSWGEGCA 455
Query: 1576 RDGKYGFYTHVFRLKKWMQK 1635
R GKYG YT V KW+ +
Sbjct: 456 RKGKYGIYTKVTNFLKWIDR 475
>ref|NP_001003323.1| coagulation factor IX [Canis familiaris]
Length = 452
Score = 164 bits (414), Expect = 3e-40
Identities = 102/284 (35%), Positives = 157/284 (55%), Gaps = 9/284 (3%)
Frame = +1
Query: 811 LFEKSSLEDKTEKELFESYIEG------RIVEGSDAEIGLAPWQVMIFRKSPQELLCGAS 972
LF E+ TE E + R+V G DA+ G PWQV++ K + CG S
Sbjct: 189 LFSNMDYENSTEVEKILDNVTQPLNDFTRVVGGKDAKPGQFPWQVLLNGKV--DAFCGGS 246
Query: 973 LISDRWVLTAAHCLLYPPWDKNFTENDLLVRI--GKHSRTRYERNIEKISMLEKIYIHPR 1146
+I+++WV+TAAHC+ E D+ + I G+H+ + E +K +++ I +H
Sbjct: 247 IINEKWVVTAAHCI----------EPDVKITIVAGEHNTEKREHTEQKRNVIRTI-LHHS 295
Query: 1147 YNWREN-LDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETW 1323
YN N + DIALL+L +P+T + ++ P+C D+E + L+ G G V+GWG +
Sbjct: 296 YNATINKYNHDIALLELDEPLTLNSYVTPICIADREYSNIFLKFG-SGYVSGWGRVFNKG 354
Query: 1324 TTSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGP 1503
++ S+LQ + +P+V+R C ST+ I +NMFCAG+ + GK D+C+GDSGGP
Sbjct: 355 RSA------SILQYLKVPLVDRATCLRSTKFTIYNNMFCAGFH-EGGK--DSCQGDSGGP 405
Query: 1504 FVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQK 1635
V + + GI+SWGE C GKYG YT V R W+++
Sbjct: 406 HV--TEVEGISFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKE 447
>ref|XP_849513.1| PREDICTED: similar to Coagulation factor VII precursor (Serum
prothrombin conversion accelerator) (SPCA) (Proconvertin)
(Eptacog alfa) [Canis familiaris]
Length = 461
Score = 155 bits (392), Expect = 1e-37
Identities = 118/379 (31%), Positives = 183/379 (48%), Gaps = 21/379 (5%)
Frame = +1
Query: 568 NFCRNPDGDQEGAWCYVAGQPGDFE--YCDLDYCEEPV----DGEVGDALGENADA---- 717
N C+N ++ Y+ P DF+ C+ + ++ + +G ++A+A
Sbjct: 108 NPCQNGGSCEDQLQSYICFCPDDFQGRNCETNKKDQLICMNENGGCQQYCSDHAEARRSC 167
Query: 718 -AIEGRTTADDFQPFFNEKTFGAGEADCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGS 894
EG T DD E CG P+ EK S +GRIV G
Sbjct: 168 WCHEGYTLQDD-----GVSCMPIVEYPCGKIPVLEKR----------IGSNPQGRIVGGK 212
Query: 895 DAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGK 1074
G PWQ + K +LLCG +LI WV++AAHC +++ +L V +G+
Sbjct: 213 VCPKGECPWQAAV--KVDGKLLCGGTLIDAAWVVSAAHC-----FERIKNWKNLTVVLGE 265
Query: 1075 HSRTR-----YERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVCP 1239
H + ER++ ++ + +K YI + N DIALL LR P+ ++D + P+C
Sbjct: 266 HDLSEDDGDEQERHVAQVIVPDK-YIPLKTN------HDIALLHLRTPVAYTDHVVPLCL 318
Query: 1240 PDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRIR 1419
P+K + + L V+GWG L + T+ L +++P V C+ +R R
Sbjct: 319 PEKTFSERTLAFIRFSTVSGWGQLLDRGATALQ------LMAIDVPRVMTQDCQEQSRRR 372
Query: 1420 -----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDG 1584
IT+NMFCAGY +G + DAC+GDSGGP K F WY G+VSWGEGC +G
Sbjct: 373 SGSPAITENMFCAGYL--DGSK-DACQGDSGGPHATK--FQGTWYLTGVVSWGEGCAAEG 427
Query: 1585 KYGFYTHVFRLKKWMQKVI 1641
+G YT V + +W+++++
Sbjct: 428 YFGVYTRVSQYIEWLRQLM 446
>ref|XP_531743.2| PREDICTED: similar to transmembrane protease, serine 6 isoform 1
[Canis familiaris]
Length = 786
Score = 151 bits (382), Expect = 2e-36
Identities = 91/256 (35%), Positives = 141/256 (55%)
Frame = +1
Query: 874 GRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 1053
GRIV G+ + G PWQ + + +CG +LI+DRWV+TAAHC
Sbjct: 550 GRIVGGAVSSEGEWPWQASLQIRGRH--ICGGALIADRWVITAAHCFQDDSMASPALWTV 607
Query: 1054 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPV 1233
L ++ + SR E + + + ++ +HP Y+ ++ D D+ALL+L P+ S + PV
Sbjct: 608 FLGKVWQSSRWPGEVSFK----VSRLLLHP-YHEEDSHDYDVALLQLDHPVVRSAAVRPV 662
Query: 1234 CPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTR 1413
C P + + G +TGWG L+E TS LQ V++ ++ + +C + R
Sbjct: 663 CLPAR---SHFFEPGLHCWITGWGALREGGPTSNG------LQKVDVQLIPQDLCSEAYR 713
Query: 1414 IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYG 1593
++T M CAGY+ +GK+ DAC+GDSGGP V K P + RW+ G+VSWG GC R +G
Sbjct: 714 YQVTPRMLCAGYR--KGKK-DACQGDSGGPLVCKEP-SGRWFLAGLVSWGLGCGRPNYFG 769
Query: 1594 FYTHVFRLKKWMQKVI 1641
YT + + W+Q+V+
Sbjct: 770 VYTRITGVIGWIQQVL 785
>ref|XP_861032.1| PREDICTED: similar to mannan-binding lectin serine protease 1 isoform
1 precursor isoform 3 [Canis familiaris]
Length = 699
Score = 147 bits (371), Expect = 3e-35
Identities = 91/272 (33%), Positives = 139/272 (51%), Gaps = 11/272 (4%)
Frame = +1
Query: 856 FESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLL------ 1017
F + RI G + G PW M+ + Q CG SL+ W++TAAHCL
Sbjct: 441 FSRKLMARIFNGRPVQKGTTPWIAMLSYPNEQPF-CGGSLLGSSWIVTAAHCLHQSLDSE 499
Query: 1018 YPPWDKN--FTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLK 1191
YP + +D V +GKH R R + N E+ +++I++HP Y+ + D+AL++
Sbjct: 500 YPALHDSDLLRPSDFKVIMGKHWRRRSDGN-EQHLRVKRIFLHPLYD-PNTFENDVALVE 557
Query: 1192 LRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVN 1371
L + +DF+ P+C P++ G V+GWG + P L +
Sbjct: 558 LLESPVLNDFVMPICLPEEPP-----EEGAIVIVSGWGK-------QFLQRFPETLMEIE 605
Query: 1372 LPIVERLVCK---ASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQ 1542
+PIV+ C+ A R ++T +M CAG K EG + DAC GDSGGP V +WY
Sbjct: 606 IPIVDHHTCQEAYAPLRKKVTRDMICAGEK--EGGK-DACAGDSGGPMVTLDRERGQWYL 662
Query: 1543 MGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKV 1638
+G VSWGE C + +YG Y++++ K W+Q+V
Sbjct: 663 VGTVSWGEDCGKKDRYGVYSYIYHNKDWIQRV 694
>ref|XP_850550.1| PREDICTED: similar to transmembrane protease, serine 6 isoform 2
[Canis familiaris]
Length = 822
Score = 145 bits (367), Expect = 1e-34
Identities = 93/272 (34%), Positives = 145/272 (53%), Gaps = 16/272 (5%)
Frame = +1
Query: 874 GRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 1053
GRIV G+ + G PWQ + + +CG +LI+DRWV+TAAHC
Sbjct: 564 GRIVGGAVSSEGEWPWQASLQIRGRH--ICGGALIADRWVITAAHCFQDDSMASPALWTV 621
Query: 1054 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPV 1233
L ++ + SR E + + + ++ +HP Y+ ++ D D+ALL+L P+ S + PV
Sbjct: 622 FLGKVWQSSRWPGEVSFK----VSRLLLHP-YHEEDSHDYDVALLQLDHPVVRSAAVRPV 676
Query: 1234 CPPDKETATKLLRAGYKGRVTGWGNLKET--------WTTSASE------VQPSV--LQV 1365
C P + + G +TGWG L+E W S + V P+ LQ
Sbjct: 677 CLPAR---SHFFEPGLHCWITGWGALREGVLRVDIVGWPRSLKQEGQCLCVCPTSNGLQK 733
Query: 1366 VNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQM 1545
V++ ++ + +C + R ++T M CAGY+ +GK+ DAC+GDSGGP V K P + RW+
Sbjct: 734 VDVQLIPQDLCSEAYRYQVTPRMLCAGYR--KGKK-DACQGDSGGPLVCKEP-SGRWFLA 789
Query: 1546 GIVSWGEGCDRDGKYGFYTHVFRLKKWMQKVI 1641
G+VSWG GC R +G YT + + W+Q+V+
Sbjct: 790 GLVSWGLGCGRPNYFGVYTRITGVIGWIQQVL 821
Database: RefSeqCP
Posted date: Aug 1, 2006 9:25 PM
Number of letters in database: 19,266,565
Number of sequences in database: 33,732
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,678,749
Number of Sequences: 33732
Number of extensions: 2483874
Number of successful extensions: 11304
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 7480
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10747
length of database: 19,266,565
effective HSP length: 109
effective length of database: 15,589,777
effective search space used: 7623400953
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqSP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= LVRM1_0010_B03
(1797 letters)
Database: RefSeqSP
1040 sequences; 434,620 total letters
Searching...done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_999083.1| protein C [Sus scrofa] 167 6e-43
Alignment gi|NP_999219.1| T-plasminogen activator [Sus scrofa] 155 4e-39
Alignment gi|NP_999239.1| kallikrein [Sus scrofa] 147 6e-37
Alignment gi|NP_999407.1| factor XII [Sus scrofa] 133 2e-32
Alignment gi|NP_001001259.1| enteropeptidase, light chain (L chain) [Sus ... 132 3e-32
Alignment gi|NP_999356.1| tryptase [Sus scrofa] 131 4e-32
Alignment gi|NP_998959.1| tryptase [Sus scrofa] 125 3e-30
Alignment gi|NP_999198.1| preproacrosin [Sus scrofa] 117 1e-27
Alignment gi|NP_999110.1| plasminogen activator [Sus scrofa] 117 1e-27
Alignment gi|NP_998967.1| enamel matrix serine proteinase 1 [Sus scrofa] 108 4e-25
>ref|NP_999083.1| protein C [Sus scrofa]
Length = 459
Score = 167 bits (424), Expect = 6e-43
Identities = 104/271 (38%), Positives = 143/271 (52%), Gaps = 1/271 (0%)
Frame = +1
Query: 820 KSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLT 999
K+ D + + E I+ R+V G + G +PWQV++ S ++L CGA LI WVLT
Sbjct: 194 KNLKRDTDQVDKKEDQIDPRLVNGKQSPWGESPWQVILL-DSKKKLACGAVLIHVSWVLT 252
Query: 1000 AAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDI 1179
AAHCL L VR+G++ R E+ + + E + +HP Y R D DI
Sbjct: 253 AAHCL--------DDYKKLTVRLGEYDLRRREKWEVDLDIKEFL-VHPNYT-RSTSDNDI 302
Query: 1180 ALLKLRKPITFSDFIHPVCPPDKETATK-LLRAGYKGRVTGWGNLKETWTTSASEVQPSV 1356
ALL+L +P TFS I P+C PD + + L R G + VTGWG E T + +
Sbjct: 303 ALLRLAEPATFSQTIVPICLPDSGLSERELTRVGQETVVTGWGYRSEAKTNRSF-----I 357
Query: 1357 LQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRW 1536
L + +P+ C + +I++NM CAG D DACEGDSGGP V + F W
Sbjct: 358 LNFIKVPVAPHNECVQAMHNKISENMLCAGILGDSR---DACEGDSGGPMV--ASFRGTW 412
Query: 1537 YQMGIVSWGEGCDRDGKYGFYTHVFRLKKWM 1629
+ +G+VSWGEGC R YG YT V R W+
Sbjct: 413 FLVGLVSWGEGCGRLHNYGVYTKVSRYLDWI 443
>ref|NP_999219.1| T-plasminogen activator [Sus scrofa]
Length = 562
Score = 155 bits (391), Expect = 4e-39
Identities = 150/535 (28%), Positives = 207/535 (38%), Gaps = 28/535 (5%)
Frame = +1
Query: 112 CAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADL---RENFCRNPDGSI 282
C E G+ YRG S T SG EC W + N L N+CRNPD
Sbjct: 127 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKD- 185
Query: 283 TGPWCYT-TSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNVSPPLETCVPERGRQYQG 459
+ PWCY + + CS P C + + E C +G Y+G
Sbjct: 186 SKPWCYIFKAEKYSPDFCSTPACTKEK--------------------EECYTGKGLDYRG 225
Query: 460 RLAVTSHGSPCLAWGS------------SQAKALSKDRDFNPAVPLVENFCRNPDGDQEG 603
++T G+ CL W S S A+ L + N+CRNPDGD +
Sbjct: 226 TRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGK---------HNYCRNPDGDTQ- 275
Query: 604 AWCYVAGQPG-DFEYCDLDYCEEPVDGEVGDALGENADAAIEGRTTADDFQPFFNEKTFG 780
WC+V +EYCDL C
Sbjct: 276 PWCHVLKDHKLTWEYCDLPQC--------------------------------------- 296
Query: 781 AGEADCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIF---RKSPQ 951
CGLR E + RI G A+I PWQ IF R+SP
Sbjct: 297 ---VTCGLRQYKEP----------------QFRIKGGLYADITSHPWQAAIFVKNRRSPG 337
Query: 952 E-LLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEK 1128
E LCG LIS WVL+AAHC + + F + + V +G+ R E+ +EK
Sbjct: 338 ERFLCGGILISSCWVLSAAHC-----FQERFPPHHVRVVLGRTYRL-VPGEEEQAFEVEK 391
Query: 1129 IYIHPRYNWRENLDRDIALLKLRKP----ITFSDFIHPVCPPDKETATKLLRAGYKGRVT 1296
+H ++ + D DIALL+L+ SD + VC P+ A L + ++
Sbjct: 392 YIVHKEFD-DDTYDNDIALLQLKSDSLTCAQESDAVRTVCLPE---ANLQLPDWTECELS 447
Query: 1297 GWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRG- 1473
G+G + + + ++ + V L R K IT+NM CAG G
Sbjct: 448 GYGKHEASSPFYSERLKEA---HVRLYPSSRCTSKHLFNKTITNNMLCAGDTRSGGDNAN 504
Query: 1474 --DACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQ 1632
DAC+GDSGGP V N +G++SWG GC + G YT V W++
Sbjct: 505 LHDACQGDSGGPLVCMK--GNHMTLVGVISWGLGCGQKDVPGVYTKVTNYLNWIR 557
>ref|NP_999239.1| kallikrein [Sus scrofa]
Length = 643
Score = 147 bits (372), Expect = 6e-37
Identities = 97/253 (38%), Positives = 134/253 (52%), Gaps = 2/253 (0%)
Frame = +1
Query: 877 RIVEGSDAEIGLAPWQVMIFRK-SPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 1053
RIV G+D+ +G PWQV + K Q LCG S+I +WVLTAAHC + D
Sbjct: 398 RIVGGTDSFLGEWPWQVSLQAKLRAQNHLCGGSIIGHQWVLTAAHCF------DGLSLPD 451
Query: 1054 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPV 1233
+ G S +++I IH Y E+ DIALLKL P+ ++DF P+
Sbjct: 452 IWRIYGGILNISEITKETPFSQVKEIIIHQNYKILES-GHDIALLKLETPLNYTDFQKPI 510
Query: 1234 CPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTR 1413
C P ++ + + VTGWG +T E+Q ++LQ VN+P+V C+ S R
Sbjct: 511 CLPSRDDTNVVYTNCW---VTGWG-----FTEEKGEIQ-NILQKVNIPLVSNEECQKSYR 561
Query: 1414 I-RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY 1590
+I+ M CAGYK EG + DAC+G+SGGP V K +N W+ +G SWGEGC R +
Sbjct: 562 DHKISKQMICAGYK--EGGK-DACKGESGGPLVCK--YNGIWHLVGTTSWGEGCARREQP 616
Query: 1591 GFYTHVFRLKKWM 1629
G YT V W+
Sbjct: 617 GVYTKVIEYMDWI 629
>ref|NP_999407.1| factor XII [Sus scrofa]
Length = 616
Score = 133 bits (334), Expect = 2e-32
Identities = 132/436 (30%), Positives = 184/436 (42%), Gaps = 31/436 (7%)
Frame = +1
Query: 421 ETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAK-ALSKDRDFNPAVPLVENFCRNPDGDQ 597
E C +RG Y+G T G+PC W S ++ ++ N + FCRNPD D
Sbjct: 215 ERCYSDRGLSYRGMAQTTLSGAPCQPWASEATYWNMTAEQALNWGLG-DHAFCRNPDNDT 273
Query: 598 EGAWCYV-AGQPGDFEYCDLDYCEEPVDGEVGDAL------GENADAAIEGR-------- 732
WC+V G ++YC L C+ P+ GE L E+ D+ + R
Sbjct: 274 R-PWCFVWRGDQLSWQYCRLARCQAPI-GEAPPILTPTQSPSEHQDSPLLSREPQPTTQT 331
Query: 733 -----TTADDFQPFFNEKTFGAGEADCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSD 897
T+A P AG CG R SSL RIV G
Sbjct: 332 PSQNLTSAWCAPPEQRGPLPSAGLVGCGQRLRKRLSSLN--------------RIVGGLV 377
Query: 898 AEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKH 1077
A G P+ ++ + C SLI+ WVLTAAHCL P +L V +G+
Sbjct: 378 ALPGAHPYIAALYWG---QNFCAGSLIAPCWVLTAAHCLQNRP-----APEELTVVLGQD 429
Query: 1078 SRTRYERNIEKISML--EKIYIHPRYNWRENLDRDIALLKLRKPITF-----SDFIHPVC 1236
R+ ++ E+ L +H Y+ + D+AL++L++ S F+ PVC
Sbjct: 430 ---RHNQSCEQCQTLAVRSYRLHESYS-PKTYQHDLALVRLKETADGCCAHPSPFVQPVC 485
Query: 1237 PPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKAST-- 1410
P + A+ G V GWG+ E +E S LQ +P++ C A+
Sbjct: 486 LP-RSVASSAEPEGALCEVAGWGHQFE-----GAEEYSSFLQEAQVPLISPERCSAADVH 539
Query: 1411 RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQM-GIVSWGEGCDRDGK 1587
T M CAG+ EG DAC+GDSGGP V + R + GIVSWG GC K
Sbjct: 540 GAAFTPGMLCAGFL--EGGT-DACQGDSGGPLVCEDETAERQLVLRGIVSWGSGCGDRLK 596
Query: 1588 YGFYTHVFRLKKWMQK 1635
G YT V W+Q+
Sbjct: 597 PGVYTDVANYLAWIQE 612
>ref|NP_001001259.1| enteropeptidase, light chain (L chain) [Sus scrofa]
Length = 1034
Score = 132 bits (331), Expect = 3e-32
Identities = 81/259 (31%), Positives = 136/259 (52%), Gaps = 1/259 (0%)
Frame = +1
Query: 868 IEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 1047
+ +IV G+D+ G PW V ++ +LLCGASL+S W+++AAHC+ + +N
Sbjct: 796 VSPKIVGGNDSREGAWPWVVALYYNG--QLLCGASLVSRDWLVSAAHCV----YGRNLEP 849
Query: 1048 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIH 1227
+ +G H + ++++I I+P YN R D DIA++ L + ++D+I
Sbjct: 850 SKWKAILGLHMTSNLTSPQIVTRLIDEIVINPHYN-RRRKDSDIAMMHLEFKVNYTDYIQ 908
Query: 1228 PVCPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKAS 1407
P+C P++ ++ G + GWG K + S ++ +LQ ++P++ C+
Sbjct: 909 PICLPEE---NQVFPPGRICSIAGWG--KVIYQGSPAD----ILQEADVPLLSNEKCQQQ 959
Query: 1408 -TRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDG 1584
IT+NM CAGY +EG D+C+GDSGGP + NNRW G+ S+G C
Sbjct: 960 MPEYNITENMMCAGY--EEGGI-DSCQGDSGGPLMCLE--NNRWLLAGVTSFGYQCALPN 1014
Query: 1585 KYGFYTHVFRLKKWMQKVI 1641
+ G Y V + +W+Q +
Sbjct: 1015 RPGVYARVPKFTEWIQSFL 1033
>ref|NP_999356.1| tryptase [Sus scrofa]
Length = 275
Score = 131 bits (330), Expect = 4e-32
Identities = 96/268 (35%), Positives = 131/268 (48%), Gaps = 12/268 (4%)
Frame = +1
Query: 880 IVEGSDAEIGLAPWQVMIFRKSPQ--ELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 1053
IV G +A PWQV + R Q + CG SLI +WVLTAAHC D
Sbjct: 31 IVGGKEAPGHKWPWQVSL-RCLDQYWKHFCGGSLIHPQWVLTAAHCFGPEKADP------ 83
Query: 1054 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPV 1233
L +R+ + Y + +++ ++ +I +HP Y + E DIALL+L P+ S + PV
Sbjct: 84 LYIRVQLGEQHLYYQ--DRLLLVSRIIVHPNY-YDEVNGADIALLELEDPVNLSSHVQPV 140
Query: 1234 C-PPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKAST 1410
PP ET K G + VTGWG++ W P L+ V +PIVE C
Sbjct: 141 TLPPASETFPK----GTRCWVTGWGDVHSGWPLPP----PYPLKQVRVPIVENSECDMQY 192
Query: 1411 RIRIT---------DNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG 1563
+ ++ D+M CAG EG D+C+GDSGGP V + N W Q G+VSWG
Sbjct: 193 HLGLSTGDNIPIVRDDMLCAG---SEGH--DSCQGDSGGPLVCR--VNGTWLQAGVVSWG 245
Query: 1564 EGCDRDGKYGFYTHVFRLKKWMQKVIDR 1647
EGC + G YT V W+ + I R
Sbjct: 246 EGCALPNRPGIYTRVTHYLDWIHQCIPR 273
>ref|NP_998959.1| tryptase [Sus scrofa]
Length = 277
Score = 125 bits (314), Expect = 3e-30
Identities = 92/265 (34%), Positives = 130/265 (49%), Gaps = 9/265 (3%)
Frame = +1
Query: 880 IVEGSDAEIGLAPWQVMI--FRKSPQELL--CGASLISDRWVLTAAHCLLYPPWDKNFTE 1047
IV G D PWQV + +R + CG SL+ +WVLTAAHC+ N
Sbjct: 31 IVGGHDVSTWKYPWQVSLRSYRVKLGRWMHHCGGSLVHPQWVLTAAHCVD----SHNLKP 86
Query: 1048 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIH 1227
D+ V++G+ Y+ ++++ +++I HP+Y DIALL+L P+T S ++
Sbjct: 87 QDVRVQVGQLKL--YDG--DQLTKVKQIIRHPKYLGFAKGGADIALLQLEAPLTLSARVN 142
Query: 1228 PVCPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKAS 1407
V P +AT + G + VTGWGN+K + S P LQ V +PIV VC
Sbjct: 143 VVGTP---SATLKVPKGKRCSVTGWGNIKH----NLSLPPPYHLQEVEVPIVANKVCNKH 195
Query: 1408 TRIR-----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGC 1572
R I +M CAG K D+C+GDSGGP + +N W Q+GIVSWG GC
Sbjct: 196 YRTGPNSKPIKADMLCAG-----SKGLDSCQGDSGGPLMCS--WNGTWVQVGIVSWGRGC 248
Query: 1573 DRDGKYGFYTHVFRLKKWMQKVIDR 1647
G Y V W+ + + R
Sbjct: 249 GLHNFPGVYIRVMSYVSWIYQYVPR 273
>ref|NP_999198.1| preproacrosin [Sus scrofa]
Length = 400
Score = 117 bits (292), Expect = 1e-27
Identities = 83/265 (31%), Positives = 125/265 (47%), Gaps = 10/265 (3%)
Frame = +1
Query: 877 RIVEGSDAEIGLAPW----QVMIFRKSPQELLCGASLISDRWVLTAAHCLL----YPPWD 1032
R+V G AE G PW Q+ ++ + + CG L++ WVLTAAHC W
Sbjct: 38 RVVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWR 97
Query: 1033 KNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITF 1212
F N+++ K + + +E+I IH +Y ++ DIAL+K+ P+
Sbjct: 98 LIFGANEVVWGSNKPVKPPLQERF-----VEEIIIHEKYVSGLEIN-DIALIKITPPVPC 151
Query: 1213 SDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERL 1392
FI P C P + RA VTGWG LKE ++ +Q + + +++L +
Sbjct: 152 GPFIGPGCLPQFKAGPP--RAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLEL---- 205
Query: 1393 VCKASTRI--RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE 1566
C ++ R+T CAGY GK D C+GDSGGP + + N + +GI SWG
Sbjct: 206 -CNSTQWYNGRVTSTNVCAGYP--RGKI-DTCQGDSGGPLMCRDRAENTFVVVGITSWGV 261
Query: 1567 GCDRDGKYGFYTHVFRLKKWMQKVI 1641
GC R + G YT + W+ I
Sbjct: 262 GCARAKRPGVYTSTWPYLNWIASKI 286
>ref|NP_999110.1| plasminogen activator [Sus scrofa]
Length = 442
Score = 117 bits (292), Expect = 1e-27
Identities = 122/426 (28%), Positives = 172/426 (40%), Gaps = 23/426 (5%)
Frame = +1
Query: 421 ETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPL---VENFCRNPDG 591
+TC G Y+G+ + G PCL W S+ + A+ L N+CRNPD
Sbjct: 70 QTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPD- 128
Query: 592 DQEGAWCYV-AGQPGDFEYCDLDYCEEPVDGEVGDALGENADAAIEGRTTADDFQPFFNE 768
+Q WCYV G + C + C GE+ A +G+ PF
Sbjct: 129 NQRRPWCYVQVGLKQLVQECMVPNCSG----------GESHRPAYDGKN------PFSTP 172
Query: 769 KTFGAGEADCG---LRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFR 939
+ E CG LRP F +IV G I PW I+R
Sbjct: 173 EKV---EFQCGQKALRPRF--------------------KIVGGKSTTIENQPWFAAIYR 209
Query: 940 K---SPQELLCGASLISDRWVLTAAHCLLYPPWDKNFT-ENDLLVRIGK---HSRTRYER 1098
+ +CG SLIS WV++A HC + N+ + D +V +G+ HS T E
Sbjct: 210 RHRGGSVTYVCGGSLISPCWVVSATHCFI------NYQHKEDYIVYLGRQTLHSSTHGEM 263
Query: 1099 NIEKISMLEKIYIHPRYNWRENL--DRDIALLKLRKP----ITFSDFIHPVC-PPDKETA 1257
E +EK+ +H Y+ ++L DIALLK+R S I +C PP A
Sbjct: 264 KFE----VEKLILHEDYS-ADSLAHHNDIALLKIRTDKGQCAQPSRSIQTICLPPVNGDA 318
Query: 1258 TKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRI--RITDN 1431
G + G+G + + P L++ + +V C+ +T
Sbjct: 319 ----HFGASCEIVGFGK-----EDPSDYLYPEQLKMTVVKLVSHRECQQPHYYGSEVTTK 369
Query: 1432 MFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVF 1611
M CA D + D+C+GDSGGP V + R GIVSWG C K G YT V
Sbjct: 370 MLCAA---DPQWKTDSCQGDSGGPLVCST--QGRLTLTGIVSWGRECAMKDKPGVYTRVS 424
Query: 1612 RLKKWM 1629
R W+
Sbjct: 425 RFLTWI 430
Score = 45.4 bits (106), Expect = 4e-06
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 8/90 (8%)
Frame = +1
Query: 112 CAEGLGMNYRGNISVTRSGIECQLWRSR-------YPHKPEVNSTMYPGADLRENFCRNP 270
C EG G +YRG + G C W S + H+P+ + G + N+CRNP
Sbjct: 72 CFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPD---ALQLGLG-KHNYCRNP 127
Query: 271 DGSITGPWCYTTSPTVRR-EACSIPVCGQG 357
D PWCY + + C +P C G
Sbjct: 128 DNQ-RRPWCYVQVGLKQLVQECMVPNCSGG 156
>ref|NP_998967.1| enamel matrix serine proteinase 1 [Sus scrofa]
Length = 254
Score = 108 bits (270), Expect = 4e-25
Identities = 74/257 (28%), Positives = 115/257 (44%), Gaps = 1/257 (0%)
Frame = +1
Query: 874 GRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 1053
G I+ G D PWQ +F + + CG L+ +WVL+AAHC +N
Sbjct: 29 GHIINGEDCNPHSQPWQAALFLED--DFFCGGVLVHPQWVLSAAHCF----------QNS 76
Query: 1054 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPV 1233
+ +G H+ + ++ HP YN ++ D+ L+KL++ ++ SD + +
Sbjct: 77 YTIGLGLHNLEPEQEPGSQMMEASLSIQHPEYN-EPSMANDLMLIKLKESVSLSDTVRNI 135
Query: 1234 CPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTR 1413
++ G V+GWG L AS P VLQ VN+ + VCKA
Sbjct: 136 -----SVVSQCPTPGDSCLVSGWGRL-------ASGRLPQVLQCVNISVASEEVCKARYG 183
Query: 1414 IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG-CDRDGKY 1590
+MFCAG D+ D+C GDSGGP + G+VS+G+ C +
Sbjct: 184 PVYHPSMFCAGGGQDQ---KDSCHGDSGGPLICNGSL------QGLVSFGQAQCGQPNVP 234
Query: 1591 GFYTHVFRLKKWMQKVI 1641
G YT++ + W+Q I
Sbjct: 235 GVYTNLCKFTDWIQTTI 251
Database: RefSeqSP
Posted date: Aug 1, 2006 7:14 PM
Number of letters in database: 434,620
Number of sequences in database: 1040
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,790,696
Number of Sequences: 1040
Number of extensions: 52909
Number of successful extensions: 283
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 163
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 220
length of database: 434,620
effective HSP length: 82
effective length of database: 349,340
effective search space used: 180259440
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqHP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= LVRM1_0010_B03
(1797 letters)
Database: RefSeqHP
39,411 sequences; 17,774,539 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_000497.1| coagulation factor II precursor [Homo sapiens] 994 0.0
Alignment gi|NP_000292.1| plasminogen [Homo sapiens] 237 3e-62
Alignment gi|NP_005568.1| lipoprotein, Lp(a) [Homo sapiens] 223 3e-58
Alignment gi|NP_000303.1| protein C (inactivator of coagulation factors V... 170 4e-42
Alignment gi|NP_000495.1| coagulation factor X preproprotein [Homo sapiens] 167 4e-41
Alignment gi|NP_000124.1| coagulation factor IX [Homo sapiens] 157 3e-38
Alignment gi|NP_002764.1| prostasin preproprotein [Homo sapiens] 150 4e-36
Alignment gi|NP_705837.1| transmembrane protease, serine 6 [Homo sapiens] 149 6e-36
Alignment gi|NP_892018.1| transmembrane protease, serine 9 [Homo sapiens] 149 8e-36
Alignment gi|NP_062562.1| coagulation factor VII precursor, isoform b [Ho... 146 5e-35
>ref|NP_000497.1| coagulation factor II precursor [Homo sapiens]
Length = 622
Score = 994 bits (2571), Expect = 0.0
Identities = 454/550 (82%), Positives = 500/550 (90%)
Frame = +1
Query: 1 YEALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQ 180
+EALES + TD FWAKYTACE+ R R+KL CLEGNCAEGLG NYRG++++TRSGIECQ
Sbjct: 71 FEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQ 130
Query: 181 LWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGR 360
LWRSRYPHKPE+NST +PGADL+ENFCRNPD S TGPWCYTT PTVRR+ CSIPVCGQ +
Sbjct: 131 LWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQ 190
Query: 361 VTAELIPRSGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRD 540
VT + PRS GS+VN+SPPLE CVP+RG+QYQGRLAVT+HG PCLAW S+QAKALSK +D
Sbjct: 191 VTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQD 250
Query: 541 FNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEEPVDGEVGDALGENADAA 720
FN AV LVENFCRNPDGD+EG WCYVAG+PGDF YCDL+YCEE V+ E GD L E++D A
Sbjct: 251 FNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRA 310
Query: 721 IEGRTTADDFQPFFNEKTFGAGEADCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDA 900
IEGRT ++Q FFN +TFG+GEADCGLRPLFEK SLEDKTE+EL ESYI+GRIVEGSDA
Sbjct: 311 IEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDA 370
Query: 901 EIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHS 1080
EIG++PWQVM+FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHS
Sbjct: 371 EIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHS 430
Query: 1081 RTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETAT 1260
RTRYERNIEKISMLEKIYIHPRYNWRENLDRDIAL+KL+KP+ FSD+IHPVC PD+ETA
Sbjct: 431 RTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAA 490
Query: 1261 KLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFC 1440
LL+AGYKGRVTGWGNLKETWT + + QPSVLQVVNLPIVER VCK STRIRITDNMFC
Sbjct: 491 SLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFC 550
Query: 1441 AGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLK 1620
AGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLK
Sbjct: 551 AGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLK 610
Query: 1621 KWMQKVIDRF 1650
KW+QKVID+F
Sbjct: 611 KWIQKVIDQF 620
>ref|NP_000292.1| plasminogen [Homo sapiens]
Length = 810
Score = 237 bits (604), Expect = 3e-62
Identities = 163/544 (29%), Positives = 238/544 (43%), Gaps = 10/544 (1%)
Frame = +1
Query: 40 WAKYTACESVRKSREKLVEC-------LEGNCAEGLGMNYRGNISVTRSGIECQLWRSRY 198
+ K +C+S S E+L + +C G G +YRG S T +G +CQ W S
Sbjct: 346 YCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMT 405
Query: 199 PHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVTAELI 378
PH+ + YP A L N+CRNPD GPWC+TT P+VR E C++ C +
Sbjct: 406 PHRHQKTPENYPNAGLTMNYCRNPDAD-KGPWCFTTDPSVRWEYCNLKKCSGTEASVVAP 464
Query: 379 PRSGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALS-KDRDFNPAV 555
P +P E C+ G+ Y+G+ A T G+PC W + + S + NP
Sbjct: 465 PPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRA 524
Query: 556 PLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEEPVDGEVGDALGENADAAIEGRT 735
L +N+CRNPDGD G WCY ++YCD+ C P
Sbjct: 525 GLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCAAP--------------------- 563
Query: 736 TADDFQPFFNEKTFGAGEADCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLA 915
DCG K +E K GR+V G A
Sbjct: 564 -----------------SFDCG------KPQVEPKK--------CPGRVVGGCVAHPHSW 592
Query: 916 PWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYE 1095
PWQV + + CG +LIS WVLTAAHCL +K+ + V +G H E
Sbjct: 593 PWQVSLRTRFGMH-FCGGTLISPEWVLTAAHCL-----EKSPRPSSYKVILGAHQEVNLE 646
Query: 1096 RNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRA 1275
++++I + ++++ P +DIALLKL P +D + P C P + ++
Sbjct: 647 PHVQEIE-VSRLFLEP-------TRKDIALLKLSSPAVITDKVIPACLP---SPNYVVAD 695
Query: 1276 GYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRI--RITDNMFCAGY 1449
+ +TGWG + T+ +L+ LP++E VC + R+ CAG+
Sbjct: 696 RTECFITGWGETQGTFGA-------GLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGH 748
Query: 1450 KPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWM 1629
D+C+GDSGGP V +++ G+ SWG GC R K G Y V R W+
Sbjct: 749 L---AGGTDSCQGDSGGPLVCFE--KDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWI 803
Query: 1630 QKVI 1641
+ V+
Sbjct: 804 EGVM 807
Score = 139 bits (351), Expect = 6e-33
Identities = 69/184 (37%), Positives = 98/184 (53%)
Frame = +1
Query: 112 CAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGP 291
C +G G NYRGN++VT SG CQ W ++ PH +P +L EN+CRNPDG P
Sbjct: 275 CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGK-RAP 333
Query: 292 WCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNVSPPLETCVPERGRQYQGRLAV 471
WC+TT+ VR E C IP C V+ E + + + ++P ++ C G+ Y+G +
Sbjct: 334 WCHTTNSQVRWEYCKIPSCDSSPVSTEQLAPT--APPELTPVVQDCYHGDGQSYRGTSST 391
Query: 472 TSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCD 651
T+ G C +W S K + P L N+CRNPD D +G WC+ +EYC+
Sbjct: 392 TTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDAD-KGPWCFTTDPSVRWEYCN 450
Query: 652 LDYC 663
L C
Sbjct: 451 LKKC 454
Score = 132 bits (333), Expect = 7e-31
Identities = 76/213 (35%), Positives = 101/213 (47%), Gaps = 1/213 (0%)
Frame = +1
Query: 49 YTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTM 228
YT R ++EC E C G NY G IS T SG+ECQ W S+ PH +
Sbjct: 165 YTTDPEKRYDYCDILEC-EEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSK 223
Query: 229 YPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNV 408
+P +L++N+CRNPD + PWC+TT P R E C IP C P S G
Sbjct: 224 FPNKNLKKNYCRNPDRELR-PWCFTTDPNKRWELCDIPRC-------TTPPPSSG----- 270
Query: 409 SPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPD 588
P C+ G Y+G +AVT G C W + ++ + P L EN+CRNPD
Sbjct: 271 --PTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPD 328
Query: 589 GDQEGAWCYVAGQPGDFEYCDLDYCE-EPVDGE 684
G + WC+ +EYC + C+ PV E
Sbjct: 329 G-KRAPWCHTTNSQVRWEYCKIPSCDSSPVSTE 360
Score = 128 bits (321), Expect = 2e-29
Identities = 66/187 (35%), Positives = 84/187 (44%)
Frame = +1
Query: 112 CAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGP 291
C G G NYRG +S T++GI CQ W S PH+P + +P L EN+CRNPD GP
Sbjct: 103 CKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGP 162
Query: 292 WCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNVSPPLETCVPERGRQYQGRLAV 471
WCYTT P R + C I C E C+ G Y G+++
Sbjct: 163 WCYTTDPEKRYDYCDILECE-----------------------EECMHCSGENYDGKISK 199
Query: 472 TSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCD 651
T G C AW S A P L +N+CRNPD + WC+ +E CD
Sbjct: 200 TMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELR-PWCFTTDPNKRWELCD 258
Query: 652 LDYCEEP 672
+ C P
Sbjct: 259 IPRCTTP 265
Score = 73.6 bits (179), Expect = 5e-13
Identities = 36/102 (35%), Positives = 49/102 (48%)
Frame = +1
Query: 418 LETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQ 597
L C G+ Y+G ++ T +G C W S+ +P+ L EN+CRNPD D
Sbjct: 100 LSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDP 159
Query: 598 EGAWCYVAGQPGDFEYCDLDYCEEPVDGEVGDALGENADAAI 723
+G WCY ++YCD+ CEE E GEN D I
Sbjct: 160 QGPWCYTTDPEKRYDYCDILECEE----ECMHCSGENYDGKI 197
>ref|NP_005568.1| lipoprotein, Lp(a) [Homo sapiens]
Length = 4548
Score = 223 bits (569), Expect = 3e-58
Identities = 156/509 (30%), Positives = 222/509 (43%), Gaps = 2/509 (0%)
Frame = +1
Query: 112 CAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGP 291
C G G +YRG S T +G CQ W S PH+ + YP L N+CRNPD TGP
Sbjct: 4124 CYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDAD-TGP 4182
Query: 292 WCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNVSPPLE-TCVPERGRQYQGRLA 468
WC+T P++R E C++ C T + P + ++ PP E C+ G+ Y+G+ A
Sbjct: 4183 WCFTMDPSIRWEYCNLTRCSDTEGTV-VAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKA 4241
Query: 469 VTSHGSPCLAWGSSQAKALSK-DRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEY 645
T G+PC W + + S N L +N+CRNPDGD G WCY F+Y
Sbjct: 4242 TTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDY 4301
Query: 646 CDLDYCEEPVDGEVGDALGENADAAIEGRTTADDFQPFFNEKTFGAGEADCGLRPLFEKS 825
CD+ C + DCG K
Sbjct: 4302 CDIPLC--------------------------------------ASSSFDCG------KP 4317
Query: 826 SLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAA 1005
+E K G IV G A PWQV + R + CG +LIS WVLTAA
Sbjct: 4318 QVEPKK--------CPGSIVGGCVAHPHSWPWQVSL-RTRFGKHFCGGTLISPEWVLTAA 4368
Query: 1006 HCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIAL 1185
HCL K+ + V +G H E ++++I + ++++ P DIAL
Sbjct: 4369 HCL-----KKSSRPSSYKVILGAHQEVNLESHVQEIE-VSRLFLEP-------TQADIAL 4415
Query: 1186 LKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQV 1365
LKL +P +D + P C P + ++ A + +TGWG + T+ T +L+
Sbjct: 4416 LKLSRPAVITDKVMPACLPSPD---YMVTARTECYITGWGETQGTFGT-------GLLKE 4465
Query: 1366 VNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQM 1545
L ++E VC I CA + + D+C+GDSGGP V +++
Sbjct: 4466 AQLLVIENEVCNHYKYI-------CAEHL---ARGTDSCQGDSGGPLVCFE--KDKYILQ 4513
Query: 1546 GIVSWGEGCDRDGKYGFYTHVFRLKKWMQ 1632
G+ SWG GC R K G Y V R W++
Sbjct: 4514 GVTSWGLGCARPNKPGVYARVSRFVTWIE 4542
Score = 130 bits (326), Expect = 5e-30
Identities = 76/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 3315 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 3358
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD + P+CYT P+VR E C++ C T
Sbjct: 3359 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-PVAAPYCYTRDPSVRWEYCNLTQCSDAEGT 3417
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ YQG +T G C AW S
Sbjct: 3418 AVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTP 3477
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ + P L++N+CRNPD WCY +EYC+L C +
Sbjct: 3478 HSHSRTPAYYPNAGLIKNYCRNPD-PVAAPWCYTTDPSVRWEYCNLTRCSD 3527
Score = 129 bits (323), Expect = 1e-29
Identities = 74/229 (32%), Positives = 104/229 (45%), Gaps = 10/229 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +Y+G +T +G CQ W
Sbjct: 3429 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYQGTYFITVTGRTCQAW 3472
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L +N+CRNPD + PWCYTT P+VR E C++ C T
Sbjct: 3473 SSMTPHSHSRTPAYYPNAGLIKNYCRNPD-PVAAPWCYTTDPSVRWEYCNLTRCSDAEWT 3531
Query: 367 AELIPRS----------GGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A + P + +P ++ C G+ Y+G + T G C AW S
Sbjct: 3532 AFVPPNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTP 3591
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYC 663
S+ + P L N+CRNPD + WCY +EYC+L C
Sbjct: 3592 HQHSRTPENYPNAGLTRNYCRNPDAEIR-PWCYTMDPSVRWEYCNLTQC 3639
Score = 128 bits (322), Expect = 1e-29
Identities = 66/187 (35%), Positives = 91/187 (48%), Gaps = 2/187 (1%)
Frame = +1
Query: 109 NCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITG 288
+C G G +YRG+ S T +G CQ W S PH + + YP L N+CRNPD I+
Sbjct: 3675 DCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIS- 3733
Query: 289 PWCYTTSPTVRREACSIPVC--GQGRVTAELIPRSGGSTVNVSPPLETCVPERGRQYQGR 462
PWCYT P VR E C++ C + V A S + SP ++ C G+ Y+G
Sbjct: 3734 PWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGS 3793
Query: 463 LAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFE 642
+ T G C +W S + ++ P L N+CRNPD + WCY +E
Sbjct: 3794 FSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIR-PWCYTMDPSVRWE 3852
Query: 643 YCDLDYC 663
YC+L C
Sbjct: 3853 YCNLTQC 3859
Score = 125 bits (313), Expect = 2e-28
Identities = 68/197 (34%), Positives = 92/197 (46%), Gaps = 10/197 (5%)
Frame = +1
Query: 109 NCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITG 288
+C G G +YRG S T +G CQ W S PH + YP A L EN+CRNPD
Sbjct: 4009 DCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSG-KQ 4067
Query: 289 PWCYTTSPTVRREACSIPVCGQGRV----TAELIP------RSGGSTVNVSPPLETCVPE 438
PWCYTT P VR E C++ C + T ++P S + +P + C
Sbjct: 4068 PWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHG 4127
Query: 439 RGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYV 618
G+ Y+G + T G C +W S + + P L N+CRNPD D G WC+
Sbjct: 4128 NGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDAD-TGPWCFT 4186
Query: 619 AGQPGDFEYCDLDYCEE 669
+EYC+L C +
Sbjct: 4187 MDPSIRWEYCNLTRCSD 4203
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 3201 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 3244
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 3245 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 3303
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 3304 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 3363
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 3364 HSHSRTPEYYPNAGLIMNYCRNPD-PVAAPYCYTRDPSVRWEYCNLTQCSD 3413
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 3087 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 3130
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 3131 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 3189
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 3190 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 3249
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 3250 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 3299
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 2973 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 3016
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 3017 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 3075
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 3076 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 3135
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 3136 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 3185
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 2859 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 2902
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 2903 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 2961
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 2962 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 3021
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 3022 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 3071
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 2745 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 2788
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 2789 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 2847
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 2848 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 2907
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 2908 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 2957
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 2631 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 2674
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 2675 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 2733
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 2734 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 2793
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 2794 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 2843
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 2517 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 2560
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 2561 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 2619
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 2620 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 2679
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 2680 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 2729
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 2403 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 2446
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 2447 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 2505
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 2506 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 2565
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 2566 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 2615
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 2289 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 2332
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 2333 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 2391
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 2392 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 2451
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 2452 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 2501
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 2175 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 2218
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 2219 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 2277
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 2278 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 2337
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 2338 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 2387
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 2061 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 2104
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 2105 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 2163
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 2164 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 2223
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 2224 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 2273
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 1947 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 1990
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 1991 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 2049
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 2050 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 2109
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 2110 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 2159
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 1833 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 1876
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 1877 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 1935
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 1936 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 1995
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 1996 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 2045
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 1719 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 1762
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 1763 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 1821
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 1822 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 1881
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 1882 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 1931
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 1605 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 1648
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 1649 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 1707
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 1708 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 1767
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 1768 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 1817
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 1491 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 1534
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 1535 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 1593
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 1594 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 1653
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 1654 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 1703
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 1377 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 1420
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 1421 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 1479
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 1480 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 1539
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 1540 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 1589
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 1263 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 1306
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 1307 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 1365
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 1366 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 1425
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 1426 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 1475
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 1149 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 1192
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 1193 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 1251
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 1252 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 1311
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 1312 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 1361
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 1035 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 1078
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 1079 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 1137
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 1138 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 1197
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 1198 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 1247
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 921 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 964
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 965 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 1023
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 1024 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 1083
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 1084 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 1133
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 807 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 850
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 851 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 909
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 910 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 969
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 970 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 1019
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 693 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 736
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 737 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 795
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 796 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 855
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 856 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 905
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 579 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 622
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 623 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 681
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 682 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 741
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 742 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 791
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 465 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 508
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 509 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 567
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 568 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 627
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 628 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 677
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 351 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 394
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 395 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 453
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 454 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 513
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 514 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 563
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 237 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 280
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 281 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 339
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 340 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 399
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 400 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 449
Score = 125 bits (313), Expect = 2e-28
Identities = 74/231 (32%), Positives = 104/231 (45%), Gaps = 10/231 (4%)
Frame = +1
Query: 7 ALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLW 186
+LE+PSE ++ + R + EC GN G +YRG S T +G CQ W
Sbjct: 123 SLEAPSE-----------QAPTEQRPGVQECYHGN-----GQSYRGTYSTTVTGRTCQAW 166
Query: 187 RSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVT 366
S PH YP A L N+CRNPD ++ P+CYT P VR E C++ C T
Sbjct: 167 SSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGT 225
Query: 367 AELIPR----------SGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQA 516
A P S + P ++ C G+ Y+G + T G C AW S
Sbjct: 226 AVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTP 285
Query: 517 KALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEE 669
+ S+ ++ P L+ N+CRNPD +CY +EYC+L C +
Sbjct: 286 HSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSD 335
Score = 124 bits (312), Expect = 2e-28
Identities = 70/201 (34%), Positives = 92/201 (45%), Gaps = 10/201 (4%)
Frame = +1
Query: 109 NCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITG 288
+C G G +YRG +S T +G CQ W S PH YP A L N+CRNPD I
Sbjct: 3895 DCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEIR- 3953
Query: 289 PWCYTTSPTVRREACSIPVCGQGRVTAELIPR----------SGGSTVNVSPPLETCVPE 438
PWCYT P+VR E C++ C + P S + SP ++ C
Sbjct: 3954 PWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYHG 4013
Query: 439 RGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYV 618
GR Y+G + T G C +W S + + P L EN+CRNPD ++ WCY
Sbjct: 4014 DGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQ-PWCYT 4072
Query: 619 AGQPGDFEYCDLDYCEEPVDG 681
+EYC+L C E G
Sbjct: 4073 TDPCVRWEYCNLTQCSETESG 4093
Score = 124 bits (311), Expect = 3e-28
Identities = 83/285 (29%), Positives = 115/285 (40%), Gaps = 14/285 (4%)
Frame = +1
Query: 109 NCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITG 288
+C G +YRG S T +G CQ W S PH+ YP A L N+CRNPD I
Sbjct: 3561 DCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEIR- 3619
Query: 289 PWCYTTSPTVRREACSIPVC----GQGRVTAELIP------RSGGSTVNVSPPLETCVPE 438
PWCYT P+VR E C++ C T ++P S + SP ++ C
Sbjct: 3620 PWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYHG 3679
Query: 439 RGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYV 618
G+ Y+G + T G C +W S + ++ P L N+CRNPD + WCY
Sbjct: 3680 DGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA-EISPWCYT 3738
Query: 619 AGQPGDFEYCDLDYCEEPVDGEVGDALGENADAAIEGRTTADDFQPFFNEKTFGAGEADC 798
+EYC+L C + + + A E T D + G+
Sbjct: 3739 MDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGSFSTTV 3798
Query: 799 GLRPLFEKSSLEDKTEKELFESYIEGRIV----EGSDAEIGLAPW 921
R SS+ + E Y G + DAEI PW
Sbjct: 3799 TGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEI--RPW 3841
Score = 123 bits (309), Expect = 4e-28
Identities = 66/197 (33%), Positives = 93/197 (47%), Gaps = 10/197 (5%)
Frame = +1
Query: 109 NCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITG 288
+C G G +YRG S T +G CQ W S PH+ + YP A L N+CRNPD ++
Sbjct: 27 DCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRNPD-AVAA 85
Query: 289 PWCYTTSPTVRREACSIPVCGQGRVTAELIPR----------SGGSTVNVSPPLETCVPE 438
P+CYT P VR E C++ C TA P S + P ++ C
Sbjct: 86 PYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHG 145
Query: 439 RGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYV 618
G+ Y+G + T G C AW S + S+ ++ P L+ N+CRNPD +CY
Sbjct: 146 NGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYT 204
Query: 619 AGQPGDFEYCDLDYCEE 669
+EYC+L C +
Sbjct: 205 RDPGVRWEYCNLTQCSD 221
Score = 119 bits (298), Expect = 8e-27
Identities = 67/196 (34%), Positives = 91/196 (46%), Gaps = 11/196 (5%)
Frame = +1
Query: 109 NCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITG 288
+C G G +YRG+ S T +G CQ W S PH + + YP L N+CRNPD I
Sbjct: 3781 DCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIR- 3839
Query: 289 PWCYTTSPTVRREACSIPVCGQGRVT-----------AELIPRSGGSTVNVSPPLETCVP 435
PWCYT P+VR E C++ C T + +P T N S ++ C
Sbjct: 3840 PWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTEN-STGVQDCYR 3898
Query: 436 ERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCY 615
G+ Y+G L+ T G C +W S + + P L N+CRNPD + WCY
Sbjct: 3899 GDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEIR-PWCY 3957
Query: 616 VAGQPGDFEYCDLDYC 663
+EYC+L C
Sbjct: 3958 TMDPSVRWEYCNLTRC 3973
Score = 83.6 bits (205), Expect = 5e-16
Identities = 39/86 (45%), Positives = 51/86 (59%), Gaps = 4/86 (4%)
Frame = +1
Query: 103 EGNCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPG----ADLRENFCRNP 270
E +C G G YRG + T +G CQ W ++ PH+ +ST PG A L +N+CRNP
Sbjct: 4225 EQDCMFGNGKGYRGKKATTVTGTPCQEWAAQEPHR---HSTFIPGTNKWAGLEKNYCRNP 4281
Query: 271 DGSITGPWCYTTSPTVRREACSIPVC 348
DG I GPWCYT +P + C IP+C
Sbjct: 4282 DGDINGPWCYTMNPRKLFDYCDIPLC 4307
Score = 52.0 bits (123), Expect = 2e-06
Identities = 25/84 (29%), Positives = 39/84 (46%)
Frame = +1
Query: 418 LETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQ 597
++ C G+ Y+G + T G C AW S ++ + P L+ N+CRNPD
Sbjct: 25 VQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRNPDA-V 83
Query: 598 EGAWCYVAGQPGDFEYCDLDYCEE 669
+CY +EYC+L C +
Sbjct: 84 AAPYCYTRDPGVRWEYCNLTQCSD 107
>ref|NP_000303.1| protein C (inactivator of coagulation factors Va and VIIIa) [Homo
sapiens]
Length = 461
Score = 170 bits (430), Expect = 4e-42
Identities = 104/272 (38%), Positives = 153/272 (56%), Gaps = 1/272 (0%)
Frame = +1
Query: 817 EKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVL 996
++S L+ TE + E ++ R+++G G +PWQV++ S ++L CGA LI WVL
Sbjct: 193 KRSHLKRDTEDQ--EDQVDPRLIDGKMTRRGDSPWQVVLL-DSKKKLACGAVLIHPSWVL 249
Query: 997 TAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRD 1176
TAAHC+ D++ LLVR+G++ R+E+ E ++++++HP Y+ + D D
Sbjct: 250 TAAHCM-----DES---KKLLVRLGEYDLRRWEK-WELDLDIKEVFVHPNYS-KSTTDND 299
Query: 1177 IALLKLRKPITFSDFIHPVCPPDKETATKLL-RAGYKGRVTGWGNLKETWTTSASEVQPS 1353
IALL L +P T S I P+C PD A + L +AG + VTGWG + A +
Sbjct: 300 IALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWG-YHSSREKEAKRNRTF 358
Query: 1354 VLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNR 1533
VL + +P+V C +++NM CAG G R DACEGDSGGP V + F+
Sbjct: 359 VLNFIKIPVVPHNECSEVMSNMVSENMLCAGIL---GDRQDACEGDSGGPMV--ASFHGT 413
Query: 1534 WYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWM 1629
W+ +G+VSWGEGC YG YT V R W+
Sbjct: 414 WFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWI 445
>ref|NP_000495.1| coagulation factor X preproprotein [Homo sapiens]
Length = 488
Score = 167 bits (422), Expect = 4e-41
Identities = 97/253 (38%), Positives = 140/253 (55%)
Frame = +1
Query: 877 RIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 1056
RIV G + + G PWQ ++ + E CG +++S+ ++LTAAHCL +
Sbjct: 234 RIVGGQECKDGECPWQALLINEE-NEGFCGGTILSEFYILTAAHCL--------YQAKRF 284
Query: 1057 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVC 1236
VR+G + T E E + +E + H R+ +E D DIA+L+L+ PITF + P C
Sbjct: 285 KVRVGDRN-TEQEEGGEAVHEVEVVIKHNRFT-KETYDFDIAVLRLKTPITFRMNVAPAC 342
Query: 1237 PPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRI 1416
P+++ A L G V+G+G E S L+++ +P V+R CK S+
Sbjct: 343 LPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTR------LKMLEVPYVDRNSCKLSSSF 396
Query: 1417 RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGF 1596
IT NMFCAGY + K+ DAC+GDSGGP V + F + ++ GIVSWGEGC R GKYG
Sbjct: 397 IITQNMFCAGY---DTKQEDACQGDSGGPHVTR--FKDTYFVTGIVSWGEGCARKGKYGI 451
Query: 1597 YTHVFRLKKWMQK 1635
YT V KW+ +
Sbjct: 452 YTKVTAFLKWIDR 464
>ref|NP_000124.1| coagulation factor IX [Homo sapiens]
Length = 461
Score = 157 bits (397), Expect = 3e-38
Identities = 94/254 (37%), Positives = 144/254 (56%), Gaps = 1/254 (0%)
Frame = +1
Query: 877 RIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 1056
R+V G DA+ G PWQV++ K + CG S+++++W++TAAHC+ T +
Sbjct: 226 RVVGGEDAKPGQFPWQVVLNGKV--DAFCGGSIVNEKWIVTAAHCVE--------TGVKI 275
Query: 1057 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWREN-LDRDIALLKLRKPITFSDFIHPV 1233
V G+H+ E +K +++ +I H YN N + DIALL+L +P+ + ++ P+
Sbjct: 276 TVVAGEHNIEETEHTEQKRNVI-RIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPI 334
Query: 1234 CPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTR 1413
C DKE L+ G G V+GWG + ++ VLQ + +P+V+R C ST+
Sbjct: 335 CIADKEYTNIFLKFG-SGYVSGWGRVFHKGRSAL------VLQYLRVPLVDRATCLRSTK 387
Query: 1414 IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYG 1593
I +NMFCAG+ EG R D+C+GDSGGP V + + + GI+SWGE C GKYG
Sbjct: 388 FTIYNNMFCAGFH--EGGR-DSCQGDSGGPHVTEVEGTS--FLTGIISWGEECAMKGKYG 442
Query: 1594 FYTHVFRLKKWMQK 1635
YT V R W+++
Sbjct: 443 IYTKVSRYVNWIKE 456
>ref|NP_002764.1| prostasin preproprotein [Homo sapiens]
Length = 343
Score = 150 bits (378), Expect = 4e-36
Identities = 97/265 (36%), Positives = 133/265 (50%), Gaps = 8/265 (3%)
Frame = +1
Query: 871 EGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 1050
+ RI GS A G PWQV I + +CG SL+S++WVL+AAHC + +
Sbjct: 42 QARITGGSSAVAGQWPWQVSITYEGVH--VCGGSLVSEQWVLSAAHC-----FPSEHHKE 94
Query: 1051 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHP 1230
V++G H Y + K+S L+ I HP Y +E DIALL+L +PITFS +I P
Sbjct: 95 AYEVKLGAHQLDSYSEDA-KVSTLKDIIPHPSY-LQEGSQGDIALLQLSRPITFSRYIRP 152
Query: 1231 VCPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKAST 1410
+C P A G VTGWG++ S S + P LQ + +P++ R C
Sbjct: 153 ICLP---AANASFPNGLHCTVTGWGHV----APSVSLLTPKPLQQLEVPLISRETCNCLY 205
Query: 1411 RIR--------ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE 1566
I + ++M CAGY EG + DAC+GDSGGP + P WY GIVSWG+
Sbjct: 206 NIDAKPEEPHFVQEDMVCAGYV--EGGK-DACQGDSGGP--LSCPVEGLWYLTGIVSWGD 260
Query: 1567 GCDRDGKYGFYTHVFRLKKWMQKVI 1641
C + G YT W+Q +
Sbjct: 261 ACGARNRPGVYTLASSYASWIQSKV 285
>ref|NP_705837.1| transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 149 bits (377), Expect = 6e-36
Identities = 95/296 (32%), Positives = 157/296 (53%), Gaps = 6/296 (2%)
Frame = +1
Query: 772 TFGAGEADCGLRPLFE---KSSLEDKTEKELFESYIEG---RIVEGSDAEIGLAPWQVMI 933
TF + C +P + + D +++E + ++G RIV G+ + G PWQ +
Sbjct: 535 TFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASL 594
Query: 934 FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKI 1113
+ +CG +LI+DRWV+TAAHC L ++ ++SR E + +
Sbjct: 595 QVRGRH--ICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFK-- 650
Query: 1114 SMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRV 1293
+ ++ +HP Y+ ++ D D+ALL+L P+ S + PVC P + + G +
Sbjct: 651 --VSRLLLHP-YHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPAR---SHFFEPGLHCWI 704
Query: 1294 TGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRG 1473
TGWG L+E S + LQ V++ ++ + +C R ++T M CAGY+ +GK+
Sbjct: 705 TGWGALREGGPIS------NALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYR--KGKK- 755
Query: 1474 DACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKVI 1641
DAC+GDSGGP V K+ + RW+ G+VSWG GC R +G YT + + W+Q+V+
Sbjct: 756 DACQGDSGGPLVCKA-LSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVV 810
>ref|NP_892018.1| transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 149 bits (376), Expect = 8e-36
Identities = 98/284 (34%), Positives = 144/284 (50%), Gaps = 1/284 (0%)
Frame = +1
Query: 793 DCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGAS 972
+CG RP EK + R+V G A G PWQV + K CGA+
Sbjct: 491 ECGARPAMEKPT----------------RVVGGFGAASGEVPWQVSL--KEGSRHFCGAT 532
Query: 973 LISDRWVLTAAHCLLYPPWDKNFTE-NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRY 1149
++ DRW+L+AAHC N T+ + +G S + KI L ++ +HP Y
Sbjct: 533 VVGDRWLLSAAHCF-------NHTKVEQVRAHLGTASLLGLGGSPVKIG-LRRVVLHPLY 584
Query: 1150 NWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWTT 1329
N LD D+A+L+L P+ F+ +I PVC P A + G K ++GWGN +E
Sbjct: 585 N-PGILDFDLAVLELASPLAFNKYIQPVCLP---LAIQKFPVGRKCMISGWGNTQE---- 636
Query: 1330 SASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFV 1509
+ +P +LQ ++ I+++ C +TD M CAG+ EGK D+C+GDSGGP
Sbjct: 637 -GNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFL--EGKV-DSCQGDSGGPLA 692
Query: 1510 MKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKVI 1641
+ +Y GIVSWG GC + K G YT + RLK W+ +++
Sbjct: 693 CEEA-PGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIM 735
Score = 144 bits (362), Expect = 3e-34
Identities = 96/286 (33%), Positives = 150/286 (52%), Gaps = 2/286 (0%)
Frame = +1
Query: 778 GAGEA--DCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQ 951
G+ EA +CGL+P + + GRIV G +A G PWQ + + +
Sbjct: 183 GSDEAHCECGLQPAWRMA----------------GRIVGGMEASPGEFPWQASL--RENK 224
Query: 952 ELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKI 1131
E CGA++I+ RW+++AAHC +++ + +G + E + + +++ I
Sbjct: 225 EHFCGAAIINARWLVSAAHC-----FNEFQDPTKWVAYVGATYLSGSEASTVRAQVVQ-I 278
Query: 1132 YIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNL 1311
HP YN + D D+A+L+L P+ F I PVC P AT + K ++GWG L
Sbjct: 279 VKHPLYN-ADTADFDVAVLELTSPLPFGRHIQPVCLP---AATHIFPPSKKCLISGWGYL 334
Query: 1312 KETWTTSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGD 1491
KE + V+P VLQ + ++++ +C + +TD M CAGY +GK D+C+GD
Sbjct: 335 KEDFL-----VKPEVLQKATVELLDQALCASLYGHSLTDRMVCAGYL--DGKV-DSCQGD 386
Query: 1492 SGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWM 1629
SGGP V + P + R++ GIVSWG GC + G Y V RL+ W+
Sbjct: 387 SGGPLVCEEP-SGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWI 431
Score = 132 bits (331), Expect = 1e-30
Identities = 100/323 (30%), Positives = 153/323 (47%), Gaps = 3/323 (0%)
Frame = +1
Query: 670 PVDGEVGDALGENADAAIEG-RTTADDFQPFFN--EKTFGAGEADCGLRPLFEKSSLEDK 840
P G G+ A++ + TTA PF + E T DCGL P ++L
Sbjct: 772 PTPGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEATTHTQLPDCGLAP----AALT-- 825
Query: 841 TEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLY 1020
RIV GS A G PWQV ++ + +E CGA L+++RW+L+AAHC
Sbjct: 826 ------------RIVGGSAAGRGEWPWQVSLWLRR-REHRCGAVLVAERWLLSAAHC--- 869
Query: 1021 PPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRK 1200
+D +G + E +E+++ +IY HP YN LD D+ALL+L
Sbjct: 870 --FDVYGDPKQWAAFLGTPFLSGAEGQLERVA---RIYKHPFYNLY-TLDYDVALLELAG 923
Query: 1201 PITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPI 1380
P+ S + P+C P+ G + +TGWG+++E + + LQ + +
Sbjct: 924 PVRRSRLVRPICLPEPAPRPP---DGTRCVITGWGSVREGGSMARQ------LQKAAVRL 974
Query: 1381 VERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSW 1560
+ C+ ++I+ M CAG+ P G D+C GD+GGP + P + RW G+ SW
Sbjct: 975 LSEQTCRRFYPVQISSRMLCAGF-PQGGV--DSCSGDAGGPLACREP-SGRWVLTGVTSW 1030
Query: 1561 GEGCDRDGKYGFYTHVFRLKKWM 1629
G GC R G YT V ++ W+
Sbjct: 1031 GYGCGRPHFPGVYTRVAAVRGWI 1053
>ref|NP_062562.1| coagulation factor VII precursor, isoform b [Homo sapiens]
Length = 444
Score = 146 bits (369), Expect = 5e-35
Identities = 96/290 (33%), Positives = 150/290 (51%), Gaps = 5/290 (1%)
Frame = +1
Query: 787 EADCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCG 966
E CG P+ EK + S +GRIV G G PWQV++ Q LCG
Sbjct: 170 EYPCGKIPILEKRNA----------SKPQGRIVGGKVCPKGECPWQVLLLVNGAQ--LCG 217
Query: 967 ASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPR 1146
+LI+ WV++AAHC +DK +L+ +G+H + ++ + E+ + ++ I
Sbjct: 218 GTLINTIWVVSAAHC-----FDKIKNWRNLIAVLGEHDLSEHDGD-EQSRRVAQVIIPST 271
Query: 1147 YNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWT 1326
Y + DIALL+L +P+ +D + P+C P++ + + L V+GWG L +
Sbjct: 272 YV-PGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGA 330
Query: 1327 TSASEVQPSVLQVVNLPIVERLVCKASTRI-----RITDNMFCAGYKPDEGKRGDACEGD 1491
T+ L V+N+P + C +R IT+ MFCAGY +G + D+C+GD
Sbjct: 331 TALE------LMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYS--DGSK-DSCKGD 381
Query: 1492 SGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKVI 1641
SGGP + + WY GIVSWG+GC G +G YT V + +W+QK++
Sbjct: 382 SGGPHA--THYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLM 429
Database: RefSeqHP
Posted date: Aug 2, 2006 12:57 AM
Number of letters in database: 17,774,539
Number of sequences in database: 39,411
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,558,902
Number of Sequences: 39411
Number of extensions: 2518480
Number of successful extensions: 12637
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 7957
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11870
length of database: 17,774,539
effective HSP length: 108
effective length of database: 13,518,151
effective search space used: 6623893990
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqMP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= LVRM1_0010_B03
(1797 letters)
Database: RefSeqMP
45,328 sequences; 21,768,885 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_034298.1| coagulation factor II [Mus musculus] 933 0.0
Alignment gi|NP_032903.2| plasminogen [Mus musculus] 241 2e-63
Alignment gi|NP_031998.2| coagulation factor X [Mus musculus] 172 1e-42
Alignment gi|NP_034302.1| coagulation factor VII [Mus musculus] 157 3e-38
Alignment gi|NP_032005.1| coagulation factor IX [Mus musculus] 157 5e-38
Alignment gi|NP_694739.1| testis serine protease 2 [Mus musculus] 155 1e-37
Alignment gi|NP_032960.1| protein C [Mus musculus] 155 1e-37
Alignment gi|NP_082178.1| type II transmembrane serine protease 6 [Mus mu... 154 4e-37
Alignment gi|XP_987964.1| PREDICTED: similar to Transmembrane protease, s... 152 9e-37
Alignment gi|XP_916084.1| PREDICTED: similar to Transmembrane protease, s... 152 9e-37
>ref|NP_034298.1| coagulation factor II [Mus musculus]
Length = 618
Score = 933 bits (2412), Expect = 0.0
Identities = 433/551 (78%), Positives = 480/551 (87%), Gaps = 1/551 (0%)
Frame = +1
Query: 1 YEALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQ 180
+EALESP +TD FWAKYT C+SVRK RE ++CLEG CA LG+NY G ++VT +GI+CQ
Sbjct: 72 FEALESPQDTDVFWAKYTVCDSVRKPRETFMDCLEGRCAMDLGVNYLGTVNVTHTGIQCQ 131
Query: 181 LWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQ-G 357
LWRSRYPHKPE+NST +PGADL+ENFCRNPD S TGPWCYTT PTVRRE CS+PVCGQ G
Sbjct: 132 LWRSRYPHKPEINSTTHPGADLKENFCRNPDSSTTGPWCYTTDPTVRREECSVPVCGQEG 191
Query: 358 RVTAELIPRSGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDR 537
R T + PRSGGS N+SPPL C+ ERGR YQG LAVT+ GSPCL W S AK LSK +
Sbjct: 192 RTTVVMTPRSGGSKDNLSPPLGQCLTERGRLYQGNLAVTTLGSPCLPWNSLPAKTLSKYQ 251
Query: 538 DFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEEPVDGEVGDALGENADA 717
DF+P V LVENFCRNPD D+EGAWCYVAGQPGDFEYC+L+YCEE V E D D
Sbjct: 252 DFDPEVKLVENFCRNPDWDEEGAWCYVAGQPGDFEYCNLNYCEEAVGEENYDV-----DE 306
Query: 718 AIEGRTTADDFQPFFNEKTFGAGEADCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSD 897
+I GRTT +F FFNEKTFG GEADCGLRPLFEK SL+D TEKEL +SYI+GRIVEG D
Sbjct: 307 SIAGRTTDAEFHTFFNEKTFGLGEADCGLRPLFEKKSLKDTTEKELLDSYIDGRIVEGWD 366
Query: 898 AEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKH 1077
AE G+APWQVM+FRKSPQELLCGASLISDRWVLTAAHC+LYPPWDKNFTENDLLVRIGKH
Sbjct: 367 AEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGKH 426
Query: 1078 SRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETA 1257
SRTRYERN+EKISMLEKIY+HPRYNWRENLDRDIALLKL+KP+ FSD+IHPVC PDK+T
Sbjct: 427 SRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTV 486
Query: 1258 TKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMF 1437
T LLRAGYKGRVTGWGNL+ETWTT+ +E+QPSVLQVVNLPIVER VCKASTRIRITDNMF
Sbjct: 487 TSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDNMF 546
Query: 1438 CAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRL 1617
CAG+K ++ KRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDR GKYGFYTHVFRL
Sbjct: 547 CAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYGFYTHVFRL 606
Query: 1618 KKWMQKVIDRF 1650
K+W+QKVID+F
Sbjct: 607 KRWIQKVIDQF 617
>ref|NP_032903.2| plasminogen [Mus musculus]
Length = 812
Score = 241 bits (614), Expect = 2e-63
Identities = 156/511 (30%), Positives = 224/511 (43%), Gaps = 3/511 (0%)
Frame = +1
Query: 112 CAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGP 291
C + G +YRG S T +G +CQ W + +PH+ +P A L N+CRNPDG GP
Sbjct: 377 CYQSDGQSYRGTSSTTITGKKCQSWAAMFPHRHSKTPENFPDAGLEMNYCRNPDGD-KGP 435
Query: 292 WCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNVSPPLETCVPERGRQYQGRLAV 471
WCYTT P+VR E C++ C + + +P S C+ G+ Y+G+ AV
Sbjct: 436 WCYTTDPSVRWEYCNLKRCSETGGSVVELPTVSQEPSGPSDSETDCMYGNGKDYRGKTAV 495
Query: 472 TSHGSPCLAWGSSQAKALS-KDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYC 648
T+ G+PC W + + S NP L +N+CRNPDGD G WCY ++YC
Sbjct: 496 TAAGTPCQGWAAQEPHRHSIFTPQTNPRAGLEKNYCRNPDGDVNGPWCYTTNPRKLYDYC 555
Query: 649 DLDYCEEPVDGEVGDALGENADAAIEGRTTADDFQPFFNEKTFGAGEADCGLRPLFEKSS 828
D+ C A +CG K
Sbjct: 556 DIPLCA-------------------------------------SASSFECG------KPQ 572
Query: 829 LEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAH 1008
+E K GR+V G A PWQ+ + + + CG +LI+ WVLTAAH
Sbjct: 573 VEPKK--------CPGRVVGGCVANPHSWPWQISLRTRFTGQHFCGGTLIAPEWVLTAAH 624
Query: 1009 CLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALL 1188
CL +K+ V +G H ++++IS + K+ + P +RDIALL
Sbjct: 625 CL-----EKSSRPEFYKVILGAHEEYIRGSDVQEIS-VAKLILEPN-------NRDIALL 671
Query: 1189 KLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVV 1368
KL +P T +D + P C P Y +TGWG + T+ L+
Sbjct: 672 KLSRPATITDKVIPACLPSPNYMVADRTICY---ITGWGETQGTFGAGR-------LKEA 721
Query: 1369 NLPIVERLVCKASTRI--RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQ 1542
LP++E VC + R+ CAG D+C+GDSGGP V +++
Sbjct: 722 QLPVIENKVCNRVEYLNNRVKSTELCAG---QLAGGVDSCQGDSGGPLVCFE--KDKYIL 776
Query: 1543 MGIVSWGEGCDRDGKYGFYTHVFRLKKWMQK 1635
G+ SWG GC R K G Y V R W+++
Sbjct: 777 QGVTSWGLGCARPNKPGVYVRVSRFVDWIER 807
Score = 138 bits (347), Expect = 2e-32
Identities = 67/187 (35%), Positives = 91/187 (48%)
Frame = +1
Query: 112 CAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGP 291
C G+G YRG +S T+SG+ CQ W + +PH P + + +P L EN+CRNPD GP
Sbjct: 103 CKTGIGNGYRGTMSRTKSGVACQKWGATFPHVPNYSPSTHPNEGLEENYCRNPDNDEQGP 162
Query: 292 WCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNVSPPLETCVPERGRQYQGRLAV 471
WCYTT P R + C+IP C E C+ G +Y+G+++
Sbjct: 163 WCYTTDPDKRYDYCNIPECE-----------------------EECMYCSGEKYEGKISK 199
Query: 472 TSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCD 651
T G C AW S A P+ L N+CRNPDG+ WC+ +EYCD
Sbjct: 200 TMSGLDCQAWDSQSPHAHGYIPAKFPSKNLKMNYCRNPDGEPR-PWCFTTDPTKRWEYCD 258
Query: 652 LDYCEEP 672
+ C P
Sbjct: 259 IPRCTTP 265
Score = 135 bits (339), Expect = 2e-31
Identities = 76/218 (34%), Positives = 99/218 (45%), Gaps = 2/218 (0%)
Frame = +1
Query: 49 YTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTM 228
YT R + EC E C G Y G IS T SG++CQ W S+ PH
Sbjct: 165 YTTDPDKRYDYCNIPEC-EEECMYCSGEKYEGKISKTMSGLDCQAWDSQSPHAHGYIPAK 223
Query: 229 YPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNV 408
+P +L+ N+CRNPDG PWC+TT PT R E C IP C T
Sbjct: 224 FPSKNLKMNYCRNPDGE-PRPWCFTTDPTKRWEYCDIPRC----------------TTPP 266
Query: 409 SPPLET--CVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRN 582
PP T C+ RG Y+G ++VT G C W ++ + P L EN+CRN
Sbjct: 267 PPPSPTYQCLKGRGENYRGTVSVTVSGKTCQRWSEQTPHRHNRTPENFPCKNLEENYCRN 326
Query: 583 PDGDQEGAWCYVAGQPGDFEYCDLDYCEEPVDGEVGDA 696
PDG + WCY +EYC++ CE + D+
Sbjct: 327 PDG-ETAPWCYTTDSQLRWEYCEIPSCESSASPDQSDS 363
Score = 87.8 bits (216), Expect = 3e-17
Identities = 37/83 (44%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Frame = +1
Query: 103 EGNCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEV-NSTMYPGADLRENFCRNPDGS 279
E +C G G +YRG +VT +G CQ W ++ PH+ + P A L +N+CRNPDG
Sbjct: 478 ETDCMYGNGKDYRGKTAVTAAGTPCQGWAAQEPHRHSIFTPQTNPRAGLEKNYCRNPDGD 537
Query: 280 ITGPWCYTTSPTVRREACSIPVC 348
+ GPWCYTT+P + C IP+C
Sbjct: 538 VNGPWCYTTNPRKLYDYCDIPLC 560
Score = 68.6 bits (166), Expect = 2e-11
Identities = 29/84 (34%), Positives = 43/84 (51%)
Frame = +1
Query: 418 LETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDRDFNPAVPLVENFCRNPDGDQ 597
L C G Y+G ++ T G C WG++ + +P L EN+CRNPD D+
Sbjct: 100 LSECKTGIGNGYRGTMSRTKSGVACQKWGATFPHVPNYSPSTHPNEGLEENYCRNPDNDE 159
Query: 598 EGAWCYVAGQPGDFEYCDLDYCEE 669
+G WCY ++YC++ CEE
Sbjct: 160 QGPWCYTTDPDKRYDYCNIPECEE 183
>ref|NP_031998.2| coagulation factor X [Mus musculus]
Length = 481
Score = 172 bits (436), Expect = 1e-42
Identities = 99/253 (39%), Positives = 140/253 (55%)
Frame = +1
Query: 877 RIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 1056
RIV G + + G PWQ ++ + E CG +++++ ++LTAAHCL
Sbjct: 231 RIVGGRECKDGECPWQALLVNED-NEGFCGGTILNEFYILTAAHCL--------HQARRF 281
Query: 1057 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVC 1236
VR+G + + E N E + ++ + H ++ R+ D DIA+L+L+ PITF + P C
Sbjct: 282 KVRVGDRNTEKEEGN-EMVHEVDVVIKHNKFQ-RDTYDYDIAVLRLKTPITFRMNVAPAC 339
Query: 1237 PPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRI 1416
P K+ A L G V+G+G E Q ++L+++ +P V+R CK ST
Sbjct: 340 LPQKDWAESTLMTQKTGIVSGFGRTHEKGR------QSNILKMLEVPYVDRNTCKLSTSF 393
Query: 1417 RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGF 1596
IT NMFCAGY E K DAC+GDSGGP V + F N +Y GIVSWGEGC R GKYG
Sbjct: 394 SITQNMFCAGY---EAKLEDACQGDSGGPHVTR--FKNTYYVTGIVSWGEGCARKGKYGI 448
Query: 1597 YTHVFRLKKWMQK 1635
YT V KW+ +
Sbjct: 449 YTKVTTFLKWIDR 461
>ref|NP_034302.1| coagulation factor VII [Mus musculus]
Length = 446
Score = 157 bits (397), Expect = 3e-38
Identities = 97/286 (33%), Positives = 156/286 (54%)
Frame = +1
Query: 787 EADCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCG 966
E CG P+ EK + + +GRIV G+ G PWQ ++ K LLCG
Sbjct: 173 EYPCGRIPVVEKRNSSSR----------QGRIVGGNVCPKGECPWQAVL--KINGLLLCG 220
Query: 967 ASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPR 1146
A L+ RW++TAAHC +D ++ V +G+H + + + E++ + ++ + +
Sbjct: 221 AVLLDARWIVTAAHC-----FDNIRYWGNITVVMGEHDFSEKDGD-EQVRRVTQVIMPDK 274
Query: 1147 YNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWT 1326
Y R ++ DIALL+L +P+TF+D++ P+C P+K + L RV+GWG L +
Sbjct: 275 YI-RGKINHDIALLRLHRPVTFTDYVVPLCLPEKSFSENTLARIRFSRVSGWGQLLDRGA 333
Query: 1327 TSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPF 1506
T+ + V +++ +E ++T +IT+NMFCAGY +G + DAC+GDSGGP
Sbjct: 334 TALELMSIEVPRLMTQDCLEHAKHSSNTP-KITENMFCAGYM--DGTK-DACKGDSGGPH 389
Query: 1507 VMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKVID 1644
+ ++ WY G+VSWGEGC G G YT V + W+ + +D
Sbjct: 390 A--THYHGTWYLTGVVSWGEGCAAIGHIGVYTRVSQYIDWLVRHMD 433
>ref|NP_032005.1| coagulation factor IX [Mus musculus]
Length = 471
Score = 157 bits (396), Expect = 5e-38
Identities = 95/254 (37%), Positives = 144/254 (56%), Gaps = 1/254 (0%)
Frame = +1
Query: 877 RIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 1056
R+V G +A+ G PWQV++ E CG ++I+++W++TAAHCL P DK +
Sbjct: 236 RVVGGENAKPGQIPWQVIL--NGEIEAFCGGAIINEKWIVTAAHCL--KPGDK------I 285
Query: 1057 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWREN-LDRDIALLKLRKPITFSDFIHPV 1233
V G+++ + E ++ +++ I H +YN N DIALL+L KP+ + ++ P+
Sbjct: 286 EVVAGEYNIDKKEDTEQRRNVIRTIP-HHQYNATINKYSHDIALLELDKPLILNSYVTPI 344
Query: 1234 CPPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTR 1413
C ++E L+ G G V+GWG + Q S+LQ + +P+V+R C ST
Sbjct: 345 CVANREYTNIFLKFG-SGYVSGWGKVFNKGR------QASILQYLRVPLVDRATCLRSTT 397
Query: 1414 IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYG 1593
I +NMFCAGY+ + GK D+CEGDSGGP V + + GI+SWGE C GKYG
Sbjct: 398 FTIYNNMFCAGYR-EGGK--DSCEGDSGGPHV--TEVEGTSFLTGIISWGEECAMKGKYG 452
Query: 1594 FYTHVFRLKKWMQK 1635
YT V R W+++
Sbjct: 453 IYTKVSRYVNWIKE 466
>ref|NP_694739.1| testis serine protease 2 [Mus musculus]
Length = 335
Score = 155 bits (393), Expect = 1e-37
Identities = 97/263 (36%), Positives = 142/263 (53%), Gaps = 6/263 (2%)
Frame = +1
Query: 877 RIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 1056
+I+ G DAE G PWQV + + +CG SLI+ +WVLTAAHC+ ++
Sbjct: 78 KIMGGVDAEEGKWPWQVSVRVRHMH--VCGGSLINSQWVLTAAHCI--------YSRIQY 127
Query: 1057 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVC 1236
V++G R+ Y +N + ++ I++HP+++ + DIALLKL+ P+ F+ I+PVC
Sbjct: 128 NVKVG--DRSVYRQNTSLVIPIKTIFVHPKFSTTIVVKNDIALLKLQHPVNFTTNIYPVC 185
Query: 1237 PPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIV------ERLVC 1398
P + K AG K VTGWG L A +V +LQ V+ ++ E L
Sbjct: 186 IPSESFPVK---AGTKCWVTGWGKL----VPGAPDVPTEILQEVDQNVILYEECNEMLKK 238
Query: 1399 KASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDR 1578
S+ + + GYK + GK DAC+GDSGGP M F N+W Q+G+VSWG C R
Sbjct: 239 ATSSSVDLVKRGMVCGYK-ERGK--DACQGDSGGP--MSCEFENKWVQVGVVSWGISCGR 293
Query: 1579 DGKYGFYTHVFRLKKWMQKVIDR 1647
G G YT V KW+ V+++
Sbjct: 294 KGYPGVYTDVAFYSKWLIAVVNQ 316
>ref|NP_032960.1| protein C [Mus musculus]
Length = 461
Score = 155 bits (392), Expect = 1e-37
Identities = 120/374 (32%), Positives = 175/374 (46%), Gaps = 14/374 (3%)
Frame = +1
Query: 562 VENFCRNPDGDQEGAWCYVAGQPGDFEYCD------LDYCEEPVDGEVGDALGENADAAI 723
+ +F + D EG +C Q F+ C L YC E +G A
Sbjct: 114 IGSFSCSCDKGWEGKFCQ---QELRFQDCRVNNGGCLHYCLEESNGR--------RCACA 162
Query: 724 EGRTTADDFQPFFNEKTFGAGEADCGLRP----LFEKSSLEDKTEKELFESYIEGRIVEG 891
G ADD + F G+ + L + LED+ E + RIV G
Sbjct: 163 PGYELADDHMRCKSTVNFPCGKLGRWIEKKRKILKRDTDLEDELEPD-------PRIVNG 215
Query: 892 SDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIG 1071
+ + G +PWQ ++ S ++L CG LI WVLTAAHC+ L VR+G
Sbjct: 216 TLTKQGDSPWQAILL-DSKKKLACGGVLIHTSWVLTAAHCVE--------GTKKLTVRLG 266
Query: 1072 KHS---RTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVCPP 1242
++ R +E +++ +++I +HP Y R + D DIALL+L +P T S I P+C P
Sbjct: 267 EYDLRRRDHWELDLD----IKEILVHPNYT-RSSSDNDIALLRLAQPATLSKTIVPICLP 321
Query: 1243 DKETATK-LLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRIR 1419
+ A + L +AG + VTGWG + + +L + +P+V R C +
Sbjct: 322 NNGLAQQELTQAGQETVVTGWGYQSDR-IKDGRRNRTFILTFIRIPLVARNECVEVMKNV 380
Query: 1420 ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFY 1599
+++NM CAG G DAC+GDSGGP V+ F W+ +G+VSWGEGC YG Y
Sbjct: 381 VSENMLCAGII---GNTRDACDGDSGGPMVVF--FRGTWFLVGLVSWGEGCGHTNNYGIY 435
Query: 1600 THVFRLKKWMQKVI 1641
T V KW+ I
Sbjct: 436 TKVGSYLKWIHSYI 449
>ref|NP_082178.1| type II transmembrane serine protease 6 [Mus musculus]
Length = 812
Score = 154 bits (388), Expect = 4e-37
Identities = 97/296 (32%), Positives = 160/296 (54%), Gaps = 6/296 (2%)
Frame = +1
Query: 772 TFGAGEADCGLRPLFE---KSSLEDKTEKELFESYIEG---RIVEGSDAEIGLAPWQVMI 933
TF + C +P E +S D ++++ + ++G RIV G+ + G PWQ +
Sbjct: 535 TFQCEDRSCVKKPNPECDGQSDCRDGSDEQHCDCGLQGLSSRIVGGTVSSEGEWPWQASL 594
Query: 934 FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKI 1113
+ +CG +LI+DRWV+TAAHC L ++ ++SR E + +
Sbjct: 595 QIRGRH--ICGGALIADRWVITAAHCFQEDSMASPKLWTVFLGKMRQNSRWPGEVSFK-- 650
Query: 1114 SMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRV 1293
+ ++++HP Y+ ++ D D+ALL+L P+ +S + PVC P + G +
Sbjct: 651 --VSRLFLHP-YHEEDSHDYDVALLQLDHPVVYSATVRPVCLPPARS--HFFEPGQHCWI 705
Query: 1294 TGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRG 1473
TGWG +E S + LQ V++ +V + +C + R +++ M CAGY+ +GK+
Sbjct: 706 TGWGAQREGGPVS------NTLQKVDVQLVPQDLCSEAYRYQVSPRMLCAGYR--KGKK- 756
Query: 1474 DACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKVI 1641
DAC+GDSGGP V + P + RW+ G+VSWG GC R +G YT V R+ W+Q+V+
Sbjct: 757 DACQGDSGGPLVCREP-SGRWFLAGLVSWGLGCGRPNFFGVYTRVTRVINWIQQVL 811
>ref|XP_987964.1| PREDICTED: similar to Transmembrane protease, serine 9 (Polyserase-1)
(Polyserine protease 1) (Polyserase-I) [Mus musculus]
Length = 1103
Score = 152 bits (385), Expect = 9e-37
Identities = 100/284 (35%), Positives = 148/284 (52%), Gaps = 1/284 (0%)
Frame = +1
Query: 793 DCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGAS 972
+CG RP +K + RIV G A G PWQ + ++ P+ CGA+
Sbjct: 531 ECGARPAMDKPT----------------RIVGGISAVSGEVPWQASL-KEGPRHF-CGAT 572
Query: 973 LISDRWVLTAAHCLLYPPWDKNFTE-NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRY 1149
++ DRW+L+AAHC N T+ + +G S + K+ L ++ +HPRY
Sbjct: 573 VVGDRWLLSAAHCF-------NHTKVEQVQAHLGTVSLLGVGGSPVKLG-LRRVALHPRY 624
Query: 1150 NWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWTT 1329
N LD D+ALL+L +P+ F+ +I PVC P A G K ++GWGN++E
Sbjct: 625 N-PGILDFDVALLELAQPLVFNKYIQPVCLP---LAIHKFPVGRKCMISGWGNMQE---- 676
Query: 1330 SASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFV 1509
+ +P +LQ ++ I+E+ +C A +TD M CAG+ EG R D+C+GDSGGP
Sbjct: 677 -GNATKPDILQKASVGIIEQKMCGALYNFSLTDRMLCAGFL--EG-RVDSCQGDSGGPLA 732
Query: 1510 MKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKVI 1641
+ +Y GIVSWG GC + K G Y + RLK W+ K +
Sbjct: 733 CEET-PGVFYLAGIVSWGIGCAQAKKPGVYARITRLKDWILKAM 775
Score = 146 bits (369), Expect = 6e-35
Identities = 95/284 (33%), Positives = 149/284 (52%)
Frame = +1
Query: 787 EADCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCG 966
+ DCG +P + + GRIV G +A G PWQV + + E CG
Sbjct: 228 QCDCGWQPAWRSA----------------GRIVGGVEAAPGEFPWQVSL--RENHEHFCG 269
Query: 967 ASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPR 1146
A++I RW+++AAHC +++ + G + E + + +L +I HP
Sbjct: 270 ATIIGARWLVSAAHC-----FNEFQDPAQWAAQAGSVHLSGSEASAVRTRVL-RIAKHPA 323
Query: 1147 YNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWT 1326
Y+ + D D+A+L+L +P+ F ++ P C P AT + G K ++GWG LKE +
Sbjct: 324 YD-ADTADFDVAVLELARPLPFGRYVQPACLP---AATHVFPPGKKCLISGWGYLKEDFL 379
Query: 1327 TSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPF 1506
V+P VLQ + ++++ +C + +TD M CAGY +GK D+C+GDSGGP
Sbjct: 380 -----VKPEVLQKATVELLDQSLCSSLYGHSLTDRMVCAGYL--DGKV-DSCQGDSGGPL 431
Query: 1507 VMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKV 1638
V + P + R++ GIVSWG GC + G YT V RL+ W+ +V
Sbjct: 432 VCEEP-SGRFFLAGIVSWGIGCAEARRPGVYTRVTRLRDWILEV 474
Score = 128 bits (321), Expect = 2e-29
Identities = 85/257 (33%), Positives = 130/257 (50%), Gaps = 6/257 (2%)
Frame = +1
Query: 877 RIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 1056
RIV GS A +G PWQV ++ + +E CGA L+++RW+L+AAHC +D
Sbjct: 871 RIVGGSAASLGEWPWQVSLWLRR-REHRCGAVLVAERWLLSAAHC-----FDIYGDPMQW 924
Query: 1057 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVC 1236
+G + E +E+++ +IY HP YN LD D+ALL+L P+ S + P+C
Sbjct: 925 AAFLGTPFLSSTEGQLERVA---RIYRHPFYN-IYTLDYDVALLELAGPVRRSRLVRPIC 980
Query: 1237 ------PPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVC 1398
PPD G + +TGWG+L+E + + LQ + ++ C
Sbjct: 981 LPGPARPPD----------GARCVITGWGSLREGGSMARQ------LQKAAVRVLSEQTC 1024
Query: 1399 KASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDR 1578
+ ++I+ M CAG+ P G D+C GD+GGP + P + +W G+ SWG GC R
Sbjct: 1025 RRFYPVQISSRMLCAGF-PQGGV--DSCSGDAGGPLACREP-SGQWVLTGVTSWGYGCGR 1080
Query: 1579 DGKYGFYTHVFRLKKWM 1629
G YT V + W+
Sbjct: 1081 PHFPGVYTRVAAVLGWI 1097
>ref|XP_916084.1| PREDICTED: similar to Transmembrane protease, serine 9 (Polyserase-1)
(Polyserine protease 1) (Polyserase-I) [Mus musculus]
Length = 1065
Score = 152 bits (385), Expect = 9e-37
Identities = 100/284 (35%), Positives = 148/284 (52%), Gaps = 1/284 (0%)
Frame = +1
Query: 793 DCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGAS 972
+CG RP +K + RIV G A G PWQ + ++ P+ CGA+
Sbjct: 493 ECGARPAMDKPT----------------RIVGGISAVSGEVPWQASL-KEGPRHF-CGAT 534
Query: 973 LISDRWVLTAAHCLLYPPWDKNFTE-NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRY 1149
++ DRW+L+AAHC N T+ + +G S + K+ L ++ +HPRY
Sbjct: 535 VVGDRWLLSAAHCF-------NHTKVEQVQAHLGTVSLLGVGGSPVKLG-LRRVALHPRY 586
Query: 1150 NWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWTT 1329
N LD D+ALL+L +P+ F+ +I PVC P A G K ++GWGN++E
Sbjct: 587 N-PGILDFDVALLELAQPLVFNKYIQPVCLP---LAIHKFPVGRKCMISGWGNMQE---- 638
Query: 1330 SASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFV 1509
+ +P +LQ ++ I+E+ +C A +TD M CAG+ EG R D+C+GDSGGP
Sbjct: 639 -GNATKPDILQKASVGIIEQKMCGALYNFSLTDRMLCAGFL--EG-RVDSCQGDSGGPLA 694
Query: 1510 MKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKVI 1641
+ +Y GIVSWG GC + K G Y + RLK W+ K +
Sbjct: 695 CEET-PGVFYLAGIVSWGIGCAQAKKPGVYARITRLKDWILKAM 737
Score = 146 bits (369), Expect = 6e-35
Identities = 95/284 (33%), Positives = 149/284 (52%)
Frame = +1
Query: 787 EADCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCG 966
+ DCG +P + + GRIV G +A G PWQV + + E CG
Sbjct: 190 QCDCGWQPAWRSA----------------GRIVGGVEAAPGEFPWQVSL--RENHEHFCG 231
Query: 967 ASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPR 1146
A++I RW+++AAHC +++ + G + E + + +L +I HP
Sbjct: 232 ATIIGARWLVSAAHC-----FNEFQDPAQWAAQAGSVHLSGSEASAVRTRVL-RIAKHPA 285
Query: 1147 YNWRENLDRDIALLKLRKPITFSDFIHPVCPPDKETATKLLRAGYKGRVTGWGNLKETWT 1326
Y+ + D D+A+L+L +P+ F ++ P C P AT + G K ++GWG LKE +
Sbjct: 286 YD-ADTADFDVAVLELARPLPFGRYVQPACLP---AATHVFPPGKKCLISGWGYLKEDFL 341
Query: 1327 TSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPF 1506
V+P VLQ + ++++ +C + +TD M CAGY +GK D+C+GDSGGP
Sbjct: 342 -----VKPEVLQKATVELLDQSLCSSLYGHSLTDRMVCAGYL--DGKV-DSCQGDSGGPL 393
Query: 1507 VMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKV 1638
V + P + R++ GIVSWG GC + G YT V RL+ W+ +V
Sbjct: 394 VCEEP-SGRFFLAGIVSWGIGCAEARRPGVYTRVTRLRDWILEV 436
Score = 128 bits (321), Expect = 2e-29
Identities = 85/257 (33%), Positives = 130/257 (50%), Gaps = 6/257 (2%)
Frame = +1
Query: 877 RIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 1056
RIV GS A +G PWQV ++ + +E CGA L+++RW+L+AAHC +D
Sbjct: 833 RIVGGSAASLGEWPWQVSLWLRR-REHRCGAVLVAERWLLSAAHC-----FDIYGDPMQW 886
Query: 1057 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDFIHPVC 1236
+G + E +E+++ +IY HP YN LD D+ALL+L P+ S + P+C
Sbjct: 887 AAFLGTPFLSSTEGQLERVA---RIYRHPFYN-IYTLDYDVALLELAGPVRRSRLVRPIC 942
Query: 1237 ------PPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVC 1398
PPD G + +TGWG+L+E + + LQ + ++ C
Sbjct: 943 LPGPARPPD----------GARCVITGWGSLREGGSMARQ------LQKAAVRVLSEQTC 986
Query: 1399 KASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDR 1578
+ ++I+ M CAG+ P G D+C GD+GGP + P + +W G+ SWG GC R
Sbjct: 987 RRFYPVQISSRMLCAGF-PQGGV--DSCSGDAGGPLACREP-SGQWVLTGVTSWGYGCGR 1042
Query: 1579 DGKYGFYTHVFRLKKWM 1629
G YT V + W+
Sbjct: 1043 PHFPGVYTRVAAVLGWI 1059
Database: RefSeqMP
Posted date: Aug 2, 2006 12:58 AM
Number of letters in database: 21,768,885
Number of sequences in database: 45,328
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,621,442
Number of Sequences: 45328
Number of extensions: 2774698
Number of successful extensions: 12857
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 8293
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12058
length of database: 21,768,885
effective HSP length: 109
effective length of database: 16,828,133
effective search space used: 8228957037
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)