Search to RefSeqBP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= LVRM1_0045_D02
(2705 letters)
Database: RefSeqBP
33,508 sequences; 16,112,626 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_776376.1| plasminogen [Bos taurus] 1423 0.0
Alignment gi|NP_001026921.1| hepatocyte growth factor [Bos taurus] 499 e-141
Alignment gi|XP_874086.1| PREDICTED: hepatocyte growth factor [Bos taurus] 499 e-141
Alignment gi|XP_592554.2| PREDICTED: similar to Hepatocyte growth factor-... 496 e-140
Alignment gi|NP_776571.2| plasminogen activator, tissue [Bos taurus] 241 2e-63
Alignment gi|NP_001014868.1| hyaluronan binding protein 2 [Bos taurus] 202 9e-52
Alignment gi|XP_886646.1| PREDICTED: similar to Serine protease hepsin (T... 199 9e-51
Alignment gi|XP_584887.2| PREDICTED: similar to Serine protease hepsin (T... 199 1e-50
Alignment gi|XP_618102.2| PREDICTED: similar to Transmembrane protease, s... 194 3e-49
Alignment gi|XP_607560.2| PREDICTED: similar to Transmembrane protease, s... 193 5e-49
>ref|NP_776376.1| plasminogen [Bos taurus]
Length = 812
Score = 1423 bits (3683), Expect = 0.0
Identities = 647/813 (79%), Positives = 705/813 (86%), Gaps = 1/813 (0%)
Frame = +2
Query: 2 SPKMDHKEVVXXXXXXXXXXXXXXXXXYVNTQGAFLFSLSRKQVAARSVEECAAKCEAET 181
SPKM+HK VV YVNTQGA L SLSRK +A RSVE+CAAKCE ET
Sbjct: 5 SPKMEHKAVVFLLLLFLKSGLGDLLDDYVNTQGASLLSLSRKNLAGRSVEDCAAKCEEET 64
Query: 182 NFICRAFQYHSKDQQCVVMAENSKTSPIARMRDVVLFEKRIYLSECKTGNGKNYRGTTSK 361
+F+CRAFQYHSK+QQCVVMAENSK +P+ RMRDV+L+EKRIYL ECKTGNG+ YRGTT++
Sbjct: 65 DFVCRAFQYHSKEQQCVVMAENSKNTPVFRMRDVILYEKRIYLLECKTGNGQTYRGTTAE 124
Query: 362 TKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRNPDNDEKGPWCYTTDPETRFDYCD 541
TKSGV CQKWS +SPH+PK+SPEKFPLAGLEENYCRNPDNDE GPWCYTTDP+ R+DYCD
Sbjct: 125 TKSGVTCQKWSATSPHVPKFSPEKFPLAGLEENYCRNPDNDENGPWCYTTDPDKRYDYCD 184
Query: 542 IPECEDECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNP 721
IPECED+CMHCSGE+YEGKI+KTMSG +CQ+W SQSPHAHGY+PSKFPNKNLKMNYCRNP
Sbjct: 185 IPECEDKCMHCSGENYEGKIAKTMSGRDCQAWDSQSPHAHGYIPSKFPNKNLKMNYCRNP 244
Query: 722 DGEPRPWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVTASGHTCQ 901
DGEPRPWCFTTDP KRWEFCDIPRCTTPPP+SGP YQCLKG G+NY GTV+VT SGHTCQ
Sbjct: 245 DGEPRPWCFTTDPQKRWEFCDIPRCTTPPPSSGPKYQCLKGTGKNYGGTVAVTESGHTCQ 304
Query: 902 RWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVRWDYCKIPSCGSSTT 1081
RWS Q+PHKHNRTPENFPCKNLEENYCRNP+GE APWCYTT+SEVRW+YC IPSC SS
Sbjct: 305 RWSEQTPHKHNRTPENFPCKNLEENYCRNPNGEKAPWCYTTNSEVRWEYCTIPSCESSPL 364
Query: 1082 STEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFP 1261
STE +D PVPPEQTPV QDCY GNG+SYRGTSSTTITGRKCQSW SMTPHRH KTP N+P
Sbjct: 365 STERMDVPVPPEQTPVPQDCYHGNGQSYRGTSSTTITGRKCQSWSSMTPHRHLKTPENYP 424
Query: 1262 NAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLS 1441
NAGLTMNYCRNPDADKSPWCYTTDPRVRWE+CNLKKCSET +QV PA Q P VE+
Sbjct: 425 NAGLTMNYCRNPDADKSPWCYTTDPRVRWEFCNLKKCSETPEQV---PAAPQAPGVENPP 481
Query: 1442 E-DCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGD 1618
E DCM G GK YRGK+ATTVAGVPCQEWAAQEPH+HSIFTPETNP++GLE+NYCRNPDGD
Sbjct: 482 EADCMIGTGKSYRGKKATTVAGVPCQEWAAQEPHQHSIFTPETNPQSGLERNYCRNPDGD 541
Query: 1619 DNGPWCYTTNPQKLFDYCDIPQCVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVS 1798
NGPWCYT NP+K FDYCD+PQC SSFDCGKPKVEPKKC R+VGGCVS PHSWPWQVS
Sbjct: 542 VNGPWCYTMNPRKPFDYCDVPQC-ESSFDCGKPKVEPKKCSGRIVGGCVSKPHSWPWQVS 600
Query: 1799 LRYRYRGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKL 1978
LR R HFCGGTLISP+WVLTA HCL+ + S YKVILGAH E + VQEI VS+L
Sbjct: 601 LR-RSSRHFCGGTLISPKWVLTAAHCLDNILALSFYKVILGAHNEKVREQSVQEIPVSRL 659
Query: 1979 FKEPSGADIALLKLSSPAVITDQVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLK 2158
F+EPS ADIALLKLS PA+IT +VIPACLP PNY+VA RT CYITGWGET+GT+G GLLK
Sbjct: 660 FREPSQADIALLKLSRPAIITKEVIPACLPPPNYMVAARTECYITGWGETQGTFGEGLLK 719
Query: 2159 EARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGV 2338
EA LPVIENKVCNR EYLDG+V ELCAGHL GG DSCQGDSGGPLVCFEKDKYILQGV
Sbjct: 720 EAHLPVIENKVCNRNEYLDGRVKPTELCAGHLIGGTDSCQGDSGGPLVCFEKDKYILQGV 779
Query: 2339 TSWGLGCALPNKPGVYVRVSRFVTWIEEIMRRN 2437
TSWGLGCA PNKPGVYVRVS +V WIEE MRRN
Sbjct: 780 TSWGLGCARPNKPGVYVRVSPYVPWIEETMRRN 812
>ref|NP_001026921.1| hepatocyte growth factor [Bos taurus]
Length = 730
Score = 499 bits (1284), Expect = e-141
Identities = 260/651 (39%), Positives = 360/651 (55%), Gaps = 21/651 (3%)
Frame = +2
Query: 539 DIPECEDECMHC---SGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNY 709
D+ E +D +C G Y+G +S T SGI+CQ W S PH H +LPS + K+L+ NY
Sbjct: 117 DLYENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENY 176
Query: 710 CRNPDGEPR-PWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVTAS 886
CRNP GE PWCFT++P R+E CDIP+C+ +C+ GE+YRG + T +
Sbjct: 177 CRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSE--------VECMTCNGESYRGPMDHTET 228
Query: 887 GHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVRWDYCKIPSC 1066
G CQRW Q+PH+H PE +P K ++NYCRNPDG+ PWCYT D + W+YC I C
Sbjct: 229 GKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMC 288
Query: 1067 GSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKT 1246
ST + D +P + T +C +G GE YRGT +T G CQ W S PH+H+ T
Sbjct: 289 AHSTMN----DTDLPMQTT----ECIQGQGEGYRGTINTIWNGIPCQRWDSQYPHQHDIT 340
Query: 1247 PGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPS 1426
P NF L NYCRNPD +SPWC+TTDP +R YC+ Q+P
Sbjct: 341 PENFKCKDLRENYCRNPDGAESPWCFTTDPNIRVGYCS------------------QIPK 382
Query: 1427 VEDLS-EDCMFGNGKRYRGKRATTVAGVPCQEWAA--QEPHRHSIFTPETNPRAGLEKNY 1597
+ S +DC GNGK Y G + T +G+ C W ++ HRH + P+ L KNY
Sbjct: 383 CDVSSGQDCYRGNGKNYMGSLSKTRSGLTCSMWDKNMEDLHRHIFWEPDATK---LNKNY 439
Query: 1598 CRNPDGDDNGPWCYTTNPQKLFDYCDIPQCVTSS-----------FDCGKPKVEPKKCPA 1744
CRNPD D +GPWCYT NP +DYC I +C + C K K
Sbjct: 440 CRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTK------QL 493
Query: 1745 RVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLTAKHCL-EKSSSPSSYKVILG 1921
RVV G + + W VSL+YR + H CGG+LI W+LTA+ C ++ Y+ LG
Sbjct: 494 RVVNG-IPTRTNVGWMVSLKYRNK-HICGGSLIKESWILTARQCFPSRNKDLKDYEAWLG 551
Query: 1922 AHEEHHLGEGV--QEIDVSKLFKEPSGADIALLKLSSPAVITDQVIPACLPTPNYVVADR 2095
H+ H G+ Q ++V++L P G+D+ LLKL+ PA++ D V LP + ++
Sbjct: 552 IHDVHGRGDEKRKQVLNVTQLVYGPEGSDLVLLKLARPAILDDFVSTIDLPNYGCTIPEK 611
Query: 2096 TACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSC 2275
T C + GWG T GLL+ A L ++ N+ C++Y ++ E+CAG C
Sbjct: 612 TTCSVYGWGYTGLINSDGLLRVAHLYIMGNEKCSQYHQGKVTLNESEICAGAENIVSGPC 671
Query: 2276 QGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIM 2428
+GD GGPLVC + ++ GV G GCA+PN+PG++VRV+ + WI +I+
Sbjct: 672 EGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 722
Score = 395 bits (1015), Expect = e-110
Identities = 185/440 (42%), Positives = 256/440 (58%), Gaps = 12/440 (2%)
Frame = +2
Query: 116 LSRKQVAARSVEECAAKCEAETN--FICRAFQYHSKDQQCVVMAENSKTSPIARM--RDV 283
L K + ++CA +C F C+AF + ++C+ NS +S + + +
Sbjct: 57 LKIKTKKMNTADQCANRCIRNKGLPFTCKAFVFDKARKRCLWFPFNSMSSGVKKEFGHEF 116
Query: 284 VLFEKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENY 463
L+E + Y+ C G G +Y+GT S TKSG+ CQ W+ PH + P + L+ENY
Sbjct: 117 DLYENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENY 176
Query: 464 CRNPDNDEKGPWCYTTDPETRFDYCDIPECED-ECMHCSGEHYEGKISKTMSGIECQSWG 640
CRNP +E GPWC+T++PE R++ CDIP+C + ECM C+GE Y G + T +G CQ W
Sbjct: 177 CRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGPMDHTETGKICQRWD 236
Query: 641 SQSPHAHGYLPSKFPNKNLKMNYCRNPDGEPRPWCFTTDPNKRWEFCDIPRC--TTPPPT 814
Q+PH H +LP ++P+K NYCRNPDG+PRPWC+T DP+ WE+C I C +T T
Sbjct: 237 HQTPHRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMCAHSTMNDT 296
Query: 815 SGP--TYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRN 988
P T +C++G+GE YRGT++ +G CQRW +Q PH+H+ TPENF CK+L ENYCRN
Sbjct: 297 DLPMQTTECIQGQGEGYRGTINTIWNGIPCQRWDSQYPHQHDITPENFKCKDLRENYCRN 356
Query: 989 PDGETAPWCYTTDSEVRWDYC-KIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESY 1165
PDG +PWC+TTD +R YC +IP C S+ QDCYRGNG++Y
Sbjct: 357 PDGAESPWCFTTDPNIRVGYCSQIPKCDVSS-----------------GQDCYRGNGKNY 399
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDAD-KSPWCYTTDPRV 1342
G+ S T +G C W H L NYCRNPD D PWCYT +P +
Sbjct: 400 MGSLSKTRSGLTCSMWDKNMEDLHRHIFWEPDATKLNKNYCRNPDDDAHGPWCYTGNPLI 459
Query: 1343 RWEYCNLKKC-SETEQQVTN 1399
W+YC + +C +T + N
Sbjct: 460 PWDYCPISRCEGDTTPTIVN 479
>ref|XP_874086.1| PREDICTED: hepatocyte growth factor [Bos taurus]
Length = 697
Score = 499 bits (1284), Expect = e-141
Identities = 260/651 (39%), Positives = 360/651 (55%), Gaps = 21/651 (3%)
Frame = +2
Query: 539 DIPECEDECMHC---SGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNY 709
D+ E +D +C G Y+G +S T SGI+CQ W S PH H +LPS + K+L+ NY
Sbjct: 84 DLYENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENY 143
Query: 710 CRNPDGEPR-PWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVTAS 886
CRNP GE PWCFT++P R+E CDIP+C+ +C+ GE+YRG + T +
Sbjct: 144 CRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSE--------VECMTCNGESYRGPMDHTET 195
Query: 887 GHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVRWDYCKIPSC 1066
G CQRW Q+PH+H PE +P K ++NYCRNPDG+ PWCYT D + W+YC I C
Sbjct: 196 GKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMC 255
Query: 1067 GSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKT 1246
ST + D +P + T +C +G GE YRGT +T G CQ W S PH+H+ T
Sbjct: 256 AHSTMN----DTDLPMQTT----ECIQGQGEGYRGTINTIWNGIPCQRWDSQYPHQHDIT 307
Query: 1247 PGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPS 1426
P NF L NYCRNPD +SPWC+TTDP +R YC+ Q+P
Sbjct: 308 PENFKCKDLRENYCRNPDGAESPWCFTTDPNIRVGYCS------------------QIPK 349
Query: 1427 VEDLS-EDCMFGNGKRYRGKRATTVAGVPCQEWAA--QEPHRHSIFTPETNPRAGLEKNY 1597
+ S +DC GNGK Y G + T +G+ C W ++ HRH + P+ L KNY
Sbjct: 350 CDVSSGQDCYRGNGKNYMGSLSKTRSGLTCSMWDKNMEDLHRHIFWEPDATK---LNKNY 406
Query: 1598 CRNPDGDDNGPWCYTTNPQKLFDYCDIPQCVTSS-----------FDCGKPKVEPKKCPA 1744
CRNPD D +GPWCYT NP +DYC I +C + C K K
Sbjct: 407 CRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTK------QL 460
Query: 1745 RVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLTAKHCL-EKSSSPSSYKVILG 1921
RVV G + + W VSL+YR + H CGG+LI W+LTA+ C ++ Y+ LG
Sbjct: 461 RVVNG-IPTRTNVGWMVSLKYRNK-HICGGSLIKESWILTARQCFPSRNKDLKDYEAWLG 518
Query: 1922 AHEEHHLGEGV--QEIDVSKLFKEPSGADIALLKLSSPAVITDQVIPACLPTPNYVVADR 2095
H+ H G+ Q ++V++L P G+D+ LLKL+ PA++ D V LP + ++
Sbjct: 519 IHDVHGRGDEKRKQVLNVTQLVYGPEGSDLVLLKLARPAILDDFVSTIDLPNYGCTIPEK 578
Query: 2096 TACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSC 2275
T C + GWG T GLL+ A L ++ N+ C++Y ++ E+CAG C
Sbjct: 579 TTCSVYGWGYTGLINSDGLLRVAHLYIMGNEKCSQYHQGKVTLNESEICAGAENIVSGPC 638
Query: 2276 QGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIM 2428
+GD GGPLVC + ++ GV G GCA+PN+PG++VRV+ + WI +I+
Sbjct: 639 EGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 689
Score = 387 bits (994), Expect = e-107
Identities = 179/412 (43%), Positives = 245/412 (59%), Gaps = 10/412 (2%)
Frame = +2
Query: 194 RAFQYHSKDQQCVVMAENSKTSPIARM--RDVVLFEKRIYLSECKTGNGKNYRGTTSKTK 367
RAF + ++C+ NS +S + + + L+E + Y+ C G G +Y+GT S TK
Sbjct: 52 RAFVFDKARKRCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGGSYKGTVSITK 111
Query: 368 SGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRNPDNDEKGPWCYTTDPETRFDYCDIP 547
SG+ CQ W+ PH + P + L+ENYCRNP +E GPWC+T++PE R++ CDIP
Sbjct: 112 SGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIP 171
Query: 548 ECED-ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPD 724
+C + ECM C+GE Y G + T +G CQ W Q+PH H +LP ++P+K NYCRNPD
Sbjct: 172 QCSEVECMTCNGESYRGPMDHTETGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPD 231
Query: 725 GEPRPWCFTTDPNKRWEFCDIPRC--TTPPPTSGP--TYQCLKGRGENYRGTVSVTASGH 892
G+PRPWC+T DP+ WE+C I C +T T P T +C++G+GE YRGT++ +G
Sbjct: 232 GKPRPWCYTLDPDTPWEYCAIKMCAHSTMNDTDLPMQTTECIQGQGEGYRGTINTIWNGI 291
Query: 893 TCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVRWDYC-KIPSCG 1069
CQRW +Q PH+H+ TPENF CK+L ENYCRNPDG +PWC+TTD +R YC +IP C
Sbjct: 292 PCQRWDSQYPHQHDITPENFKCKDLRENYCRNPDGAESPWCFTTDPNIRVGYCSQIPKCD 351
Query: 1070 SSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTP 1249
S+ QDCYRGNG++Y G+ S T +G C W H
Sbjct: 352 VSS-----------------GQDCYRGNGKNYMGSLSKTRSGLTCSMWDKNMEDLHRHIF 394
Query: 1250 GNFPNAGLTMNYCRNPDAD-KSPWCYTTDPRVRWEYCNLKKC-SETEQQVTN 1399
L NYCRNPD D PWCYT +P + W+YC + +C +T + N
Sbjct: 395 WEPDATKLNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVN 446
>ref|XP_592554.2| PREDICTED: similar to Hepatocyte growth factor-like protein precursor
(Macrophage stimulatory protein) (MSP) (Macrophage
stimulating protein) [Bos taurus]
Length = 711
Score = 496 bits (1276), Expect = e-140
Identities = 266/672 (39%), Positives = 361/672 (53%), Gaps = 26/672 (3%)
Frame = +2
Query: 494 PWCYTTDPETRFDY---CDIPECEDECMHC---SGEHYEGKISKTMSGIECQSWGSQSPH 655
PW + P TR CD+ + ++ C +G Y G ++ T+ G+ CQ W + P+
Sbjct: 82 PWTQHS-PHTRLQRSGRCDLFQKKNYVRTCIVDNGVEYRGTVAITVGGLPCQRWSHRFPN 140
Query: 656 AHGYLPSKFPNKNLKMNYCRNPDGEPR-PWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQ 832
H + P+ L+ N+CRNPD +P PWC+TTDP R++ C I C
Sbjct: 141 DHKFTPTL--RNGLEENFCRNPDRDPGGPWCYTTDPAVRFQSCGIKSCREAT-------- 190
Query: 833 CLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPW 1012
CL GE+YRG+V T SG CQRW Q PH H P F KNL++NYCRNPDG PW
Sbjct: 191 CLWCNGEDYRGSVDSTESGRECQRWDLQHPHPHPFEPGKFLDKNLDDNYCRNPDGSERPW 250
Query: 1013 CYTTDSEVRWDYCKIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTIT 1192
CYTTD ++ ++C +P CGS P Q +C+RG GE YRGT +TT
Sbjct: 251 CYTTDPQMEREFCDLPRCGSEAQ----------PSQEATTLNCFRGKGEGYRGTVNTTAA 300
Query: 1193 GRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYC-NLKK 1369
G CQ W + PH+H P + L N+CRNPD ++PWC+T+ P +R +C +++
Sbjct: 301 GVPCQRWDAQLPHQHRFAPEKYACKDLRENFCRNPDGSEAPWCFTSRPGMRMAFCYQIRR 360
Query: 1370 CSETEQQVTNFPAIAQVPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHS 1549
C++ + EDC G G+ YRG + T G+ CQ W+A+ PH+
Sbjct: 361 CTDDVRP-----------------EDCYHGAGELYRGSVSKTRKGIRCQNWSAETPHKPQ 403
Query: 1550 IFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDIPQCVTSS---------- 1699
F + P LE+N+CRNPDGD +GPWCYTT+P FDYC + +C
Sbjct: 404 -FKHTSAPHTPLEENFCRNPDGDSHGPWCYTTDPGTPFDYCALRRCDDDQQPSILETAHQ 462
Query: 1700 --FD-CGK--PKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLT 1864
FD CGK +V+P RVVGG P + PW VSLR R HFCGG+L+ +WVLT
Sbjct: 463 VLFDKCGKRVTRVDPLHSKLRVVGGQ---PGNSPWTVSLRNRQGQHFCGGSLVKEQWVLT 519
Query: 1865 AKHCLEKSS-SPSSYKVILGA-HEEHHLGE-GVQEIDVSKLFKEPSGADIALLKLSSPAV 2035
A+ C S Y+V LG ++ GE +Q I ++K+ PSG+ + LLKL P +
Sbjct: 520 ARQCFSSCHMSLVGYEVWLGTLFQDPQPGEPDLQHIPMAKMVCGPSGSQLVLLKLERPVI 579
Query: 2036 ITDQVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLD 2215
+ +V CLP YVV T C I GWGETKGT +L A L VI N+ CN
Sbjct: 580 LNQRVALICLPPERYVVPPGTRCEIAGWGETKGTGDDTVLNIALLSVISNQECNVKH--R 637
Query: 2216 GKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRV 2395
G+V E+C L + +C+GD GGPL CF D ++LQG+ CA P P +++RV
Sbjct: 638 GRVRESEMCTAGLLAPVGACEGDYGGPLACFTHDCWVLQGIIIPNRVCARPRWPAIFMRV 697
Query: 2396 SRFVTWIEEIMR 2431
S FV WI ++MR
Sbjct: 698 SVFVDWIHKVMR 709
Score = 399 bits (1025), Expect = e-111
Identities = 201/459 (43%), Positives = 259/459 (56%), Gaps = 7/459 (1%)
Frame = +2
Query: 143 SVEECAAKCEAETNFICRAFQYHSKDQQCVVM--AENSKTSPIARMRDVVLFEKRIYLSE 316
+ EECA C + CRAF Y+ C ++ ++S + + R LF+K+ Y+
Sbjct: 52 NAEECAGLCGPLLD--CRAFHYNLSSHGCQLLPWTQHSPHTRLQRSGRCDLFQKKNYVRT 109
Query: 317 CKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRNPDNDEKGP 496
C NG YRGT + T G+ CQ+WS P+ K++P GLEEN+CRNPD D GP
Sbjct: 110 CIVDNGVEYRGTVAITVGGLPCQRWSHRFPNDHKFTPTL--RNGLEENFCRNPDRDPGGP 167
Query: 497 WCYTTDPETRFDYCDIPEC-EDECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLP 673
WCYTTDP RF C I C E C+ C+GE Y G + T SG ECQ W Q PH H + P
Sbjct: 168 WCYTTDPAVRFQSCGIKSCREATCLWCNGEDYRGSVDSTESGRECQRWDLQHPHPHPFEP 227
Query: 674 SKFPNKNLKMNYCRNPDGEPRPWCFTTDPNKRWEFCDIPRC--TTPPPTSGPTYQCLKGR 847
KF +KNL NYCRNPDG RPWC+TTDP EFCD+PRC P T C +G+
Sbjct: 228 GKFLDKNLDDNYCRNPDGSERPWCYTTDPQMEREFCDLPRCGSEAQPSQEATTLNCFRGK 287
Query: 848 GENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTD 1027
GE YRGTV+ TA+G CQRW AQ PH+H PE + CK+L EN+CRNPDG APWC+T+
Sbjct: 288 GEGYRGTVNTTAAGVPCQRWDAQLPHQHRFAPEKYACKDLRENFCRNPDGSEAPWCFTSR 347
Query: 1028 SEVRWDYC-KIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKC 1204
+R +C +I C V PE DCY G GE YRG+ S T G +C
Sbjct: 348 PGMRMAFCYQIRRCTDD----------VRPE------DCYHGAGELYRGSVSKTRKGIRC 391
Query: 1205 QSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADK-SPWCYTTDPRVRWEYCNLKKCSET 1381
Q+W + TPH+ + + P+ L N+CRNPD D PWCYTTDP ++YC L++C +
Sbjct: 392 QNWSAETPHKPQFKHTSAPHTPLEENFCRNPDGDSHGPWCYTTDPGTPFDYCALRRCDDD 451
Query: 1382 EQQVTNFPAIAQVPSVEDLSEDCMFGNGKRYRGKRATTV 1498
+Q PS+ + + +F GKR T V
Sbjct: 452 QQ-----------PSILETAHQVLFDK----CGKRVTRV 475
>ref|NP_776571.2| plasminogen activator, tissue [Bos taurus]
Length = 566
Score = 241 bits (616), Expect = 2e-63
Identities = 162/466 (34%), Positives = 228/466 (48%), Gaps = 35/466 (7%)
Frame = +2
Query: 1139 CYRGNGESYRGTSSTTITGRKCQSW----VSMTPHRHEKTPGNFPNA---GL-TMNYCRN 1294
CY+ G +YRGT ST +G +C +W ++M P+ G PNA GL NYCRN
Sbjct: 128 CYKDQGVAYRGTWSTAESGAECANWNSSGLAMKPYS-----GRRPNAIRLGLGNHNYCRN 182
Query: 1295 PDADKSPWCYTTDP-RVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSEDCMFGNGKR 1471
PD D PWCY + E+C+ C++ ++ DC GNG
Sbjct: 183 PDQDSKPWCYVFKAGKYISEFCSTPACAKVAEE----------------DGDCYTGNGLA 226
Query: 1472 YRGKRATTVAGVPCQEWAAQEPHRHSIFTPETN-PRAGLEK-NYCRNPDGDDNGPWCYTT 1645
YRG R+ T +G C W + ++N P GL K N+CRNPDGD PWC+
Sbjct: 227 YRGTRSHTKSGASCLPWNSVFLTSKIYTAWKSNAPALGLGKHNHCRNPDGDAQ-PWCHVW 285
Query: 1646 NPQKL-FDYCDIPQCVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGH 1822
++L ++YCD+PQCVT CG + K+ R+ GG + S PWQ ++ + R
Sbjct: 286 KDRQLTWEYCDVPQCVT----CGLRQY--KRPQFRIKGGLFADITSHPWQAAIFVKNRRS 339
Query: 1823 -----FCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLF-- 1981
CGG LIS WVL+A HC ++ P KV LG GE Q +V K
Sbjct: 340 PGERFLCGGILISSCWVLSAAHCFQERYPPLHLKVFLGRTYRLVPGEEEQTFEVEKYIIH 399
Query: 1982 ----KEPSGADIALLKLSSPAVI----TDQVIPACLPTPNYVVADRTACYITGWG--ETK 2131
+ DIALL L S ++ + V CLP + + D T C ++G+G E+
Sbjct: 400 KEFDDDTYDNDIALLHLKSDSLTCARESASVRTICLPDASLQLPDWTECELSGYGKHESS 459
Query: 2132 GTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGG------IDSCQGDSGG 2293
+ + LKEA + + + C + V++ LCAG G D+CQGDSGG
Sbjct: 460 SPFFSERLKEAHVRLYPSSRCTSQHLFNRTVTNNMLCAGDTRSGGDHTNLHDACQGDSGG 519
Query: 2294 PLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIMR 2431
PLVC + + L G+ SWGLGC + PGVY +V+ ++ WI + R
Sbjct: 520 PLVCMKDNHMTLVGIISWGLGCGRKDVPGVYTKVTNYLDWIRDNTR 565
Score = 123 bits (309), Expect = 7e-28
Identities = 78/227 (34%), Positives = 102/227 (44%), Gaps = 15/227 (6%)
Frame = +2
Query: 737 PWCFTTDPNKRWEFCDIPRCTTPPPTSGP------TYQCLKGRGENYRGTVSVTASGHTC 898
PWCF ++ + C P G T C K +G YRGT S SG C
Sbjct: 90 PWCFNGGTCRQALYSSDFVCQCPEGFMGKLCEIDATATCYKDQGVAYRGTWSTAESGAEC 149
Query: 899 QRWS----AQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDS-EVRWDYCKIPS 1063
W+ A P+ R P NYCRNPD ++ PWCY + + ++C P+
Sbjct: 150 ANWNSSGLAMKPYS-GRRPNAIRLGLGNHNYCRNPDQDSKPWCYVFKAGKYISEFCSTPA 208
Query: 1064 CGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSW--VSMTPHRH 1237
C A V E DCY GNG +YRGT S T +G C W V +T +
Sbjct: 209 C-----------AKVAEEDG----DCYTGNGLAYRGTRSHTKSGASCLPWNSVFLTSKIY 253
Query: 1238 EKTPGNFPNAGL-TMNYCRNPDADKSPWCYT-TDPRVRWEYCNLKKC 1372
N P GL N+CRNPD D PWC+ D ++ WEYC++ +C
Sbjct: 254 TAWKSNAPALGLGKHNHCRNPDGDAQPWCHVWKDRQLTWEYCDVPQC 300
Score = 110 bits (276), Expect = 4e-24
Identities = 66/176 (37%), Positives = 81/176 (46%), Gaps = 14/176 (7%)
Frame = +2
Query: 317 CKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYS---PEKFPLAGLEENYCRNPDNDE 487
C G YRGT S +SG C W+ S + YS P L NYCRNPD D
Sbjct: 128 CYKDQGVAYRGTWSTAESGAECANWNSSGLAMKPYSGRRPNAIRLGLGNHNYCRNPDQDS 187
Query: 488 KGPWCYTTDPETRF-DYCDIPEC------EDECMHCSGEHYEGKISKTMSGIECQSWGSQ 646
K PWCY ++C P C + +C +G Y G S T SG C W S
Sbjct: 188 K-PWCYVFKAGKYISEFCSTPACAKVAEEDGDCYTGNGLAYRGTRSHTKSGASCLPWNSV 246
Query: 647 SPHAHGYLP--SKFPNKNL-KMNYCRNPDGEPRPWCFT-TDPNKRWEFCDIPRCTT 802
+ Y S P L K N+CRNPDG+ +PWC D WE+CD+P+C T
Sbjct: 247 FLTSKIYTAWKSNAPALGLGKHNHCRNPDGDAQPWCHVWKDRQLTWEYCDVPQCVT 302
Score = 70.5 bits (171), Expect = 7e-12
Identities = 37/84 (44%), Positives = 49/84 (58%), Gaps = 4/84 (4%)
Frame = +2
Query: 314 ECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEK--FPLAGL-EENYCRNPDND 484
+C TGNG YRGT S TKSG C W+ Y+ K P GL + N+CRNPD D
Sbjct: 218 DCYTGNGLAYRGTRSHTKSGASCLPWNSVFLTSKIYTAWKSNAPALGLGKHNHCRNPDGD 277
Query: 485 EKGPWCYT-TDPETRFDYCDIPEC 553
+ PWC+ D + ++YCD+P+C
Sbjct: 278 AQ-PWCHVWKDRQLTWEYCDVPQC 300
>ref|NP_001014868.1| hyaluronan binding protein 2 [Bos taurus]
Length = 558
Score = 202 bits (515), Expect = 9e-52
Identities = 130/375 (34%), Positives = 185/375 (49%), Gaps = 44/375 (11%)
Frame = +2
Query: 1442 EDCMFGNGKRYRGKRATTVAGVPCQEWAAQE--PHRHSIFTPETNPRAGLEKNYCRNPDG 1615
+DC +G YRG+ + T+ C W + ++++F + E N+CRNPDG
Sbjct: 190 DDCYVDDGYSYRGRVSKTIHQHTCLYWNSHLLLQEKYNMFMEDAEAHGIGEHNFCRNPDG 249
Query: 1616 DDNGPWCY--TTNPQKLFDYCDIPQCVTSSFD--------------------CGKPKVEP 1729
D PWC+ N + ++YCD+P C S+ D CG+ ++
Sbjct: 250 DKK-PWCFIKVNNVKVKWEYCDVPAC--SALDVANPEGRPTEPLTKFPEFGSCGRTEIAE 306
Query: 1730 KKCPARVVGGCVSIPHSWPWQVSLRYRYR-------GHFCGGTLISPEWVLTAKHCLEKS 1888
KK R+ GG S PWQ SL+ R GH+CGG LI P WVLTA HC E
Sbjct: 307 KKVK-RIFGGFKSTAGKHPWQASLQTSLRLTVSTPQGHYCGGALIHPCWVLTAAHCTEIK 365
Query: 1889 SSPSSYKVILGAHEEHHLGEGVQEIDVSKLFK--------EPSGADIALLKLSSP----A 2032
+ KV+LG + Q V K+FK + DIALLKL A
Sbjct: 366 TK--YLKVVLGDQDLTKTEFHEQSFGVQKIFKYSHYIEIDDIPYNDIALLKLKPVDGHCA 423
Query: 2033 VITDQVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYL 2212
+ + V CLP ++ T CYI+GWG T+ G+ L +A++ +I N +CN +
Sbjct: 424 LESKYVKTVCLPDGPFLSG--TECYISGWGVTETGEGSRHLLDAKVKLISNTICNSRQLY 481
Query: 2213 DGKVSSKELCAGHL-AGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYV 2389
D + +CAG+L G DSCQGDSGGPL C + + G+ SWGL C +PGVY
Sbjct: 482 DHSIDDNMICAGNLQKPGQDSCQGDSGGPLTCEKDGTSYIYGIVSWGLECG--KRPGVYT 539
Query: 2390 RVSRFVTWIEEIMRR 2434
+V++F+TWI+ M +
Sbjct: 540 QVTKFLTWIKATMEK 554
Score = 71.6 bits (174), Expect = 3e-12
Identities = 67/284 (23%), Positives = 109/284 (38%), Gaps = 39/284 (13%)
Frame = +2
Query: 413 PKYSPEKFPLAGLEENYCRNPDNDEKGPWCYTTDPETRFDYCDIPECEDECMH-----CS 577
P ++P+++ + + Y N + + Y+ +P+ ++ D P + C H S
Sbjct: 35 PDWTPDQYEYS---QEY-NNQEENASSTTAYSDNPDWYYEEDD-PCLSNPCTHGGDCLVS 89
Query: 578 GEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEPRPWCFTTD 757
G + + SG CQ+ + +K N C P C
Sbjct: 90 GATFTCRCPDPFSGNRCQN-----------VQNKCKNNPCGRGDCLITQSPPYHRCACKH 138
Query: 758 PNKRWEFCD--IPRCTTPPPTSGPT---------YQC-----LKGR-------------G 850
P R C +P C P +G T + C KG+ G
Sbjct: 139 PY-RGSDCSRVVPVCRPNPCQNGGTCSRQRRRSKFTCACPDQFKGKLCEIGPDDCYVDDG 197
Query: 851 ENYRGTVSVTASGHTCQRWSAQS--PHKHNRTPENFPCKNL-EENYCRNPDGETAPWCY- 1018
+YRG VS T HTC W++ K+N E+ + E N+CRNPDG+ PWC+
Sbjct: 198 YSYRGRVSKTIHQHTCLYWNSHLLLQEKYNMFMEDAEAHGIGEHNFCRNPDGDKKPWCFI 257
Query: 1019 -TTDSEVRWDYCKIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYR 1147
+ +V+W+YC +P+C + + P + P C R
Sbjct: 258 KVNNVKVKWEYCDVPACSALDVANPEGRPTEPLTKFPEFGSCGR 301
Score = 67.4 bits (163), Expect = 6e-11
Identities = 42/132 (31%), Positives = 60/132 (45%), Gaps = 16/132 (12%)
Frame = +2
Query: 1136 DCYRGNGESYRGTSSTTITGRKCQSWVS--MTPHRHEKTPGNFPNAGL-TMNYCRNPDAD 1306
DCY +G SYRG S TI C W S + ++ + G+ N+CRNPD D
Sbjct: 191 DCYVDDGYSYRGRVSKTIHQHTCLYWNSHLLLQEKYNMFMEDAEAHGIGEHNFCRNPDGD 250
Query: 1307 KSPWCY--TTDPRVRWEYCNLKKCSETE---------QQVTNFPAIAQVPSVEDLSEDC- 1450
K PWC+ + +V+WEYC++ CS + + +T FP E +
Sbjct: 251 KKPWCFIKVNNVKVKWEYCDVPACSALDVANPEGRPTEPLTKFPEFGSCGRTEIAEKKVK 310
Query: 1451 -MFGNGKRYRGK 1483
+FG K GK
Sbjct: 311 RIFGGFKSTAGK 322
Score = 66.2 bits (160), Expect = 1e-10
Identities = 65/250 (26%), Positives = 95/250 (38%), Gaps = 41/250 (16%)
Frame = +2
Query: 464 CRNPDNDEKGPWCYTTDPETRFDYCDIPE------CE---DECMHCSGEHYEGKISKTMS 616
CR P+ + G C ++F C P+ CE D+C G Y G++SKT+
Sbjct: 152 CR-PNPCQNGGTCSRQRRRSKFT-CACPDQFKGKLCEIGPDDCYVDDGYSYRGRVSKTIH 209
Query: 617 GIECQSWGSQSPHAHGYLPSKFPNKNLKM-----------NYCRNPDGEPRPWCF--TTD 757
C W S H L K+ N+ M N+CRNPDG+ +PWCF +
Sbjct: 210 QHTCLYWNS-----HLLLQEKY---NMFMEDAEAHGIGEHNFCRNPDGDKKPWCFIKVNN 261
Query: 758 PNKRWEFCDIPRCT-----------TPPPTSGPTY------QCLKGRGENYRGTVSVTAS 886
+WE+CD+P C+ T P T P + + + + + G TA
Sbjct: 262 VKVKWEYCDVPACSALDVANPEGRPTEPLTKFPEFGSCGRTEIAEKKVKRIFGGFKSTAG 321
Query: 887 GHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTD--SEVRWDYCKIP 1060
H Q S TP+ C + C W T +E++ Y K+
Sbjct: 322 KHPWQASLQTSLRLTVSTPQGHYCGGALIHPC---------WVLTAAHCTEIKTKYLKVV 372
Query: 1061 SCGSSTTSTE 1090
T TE
Sbjct: 373 LGDQDLTKTE 382
Score = 57.8 bits (138), Expect = 4e-08
Identities = 31/85 (36%), Positives = 46/85 (54%), Gaps = 5/85 (5%)
Frame = +2
Query: 314 ECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSP--EKFPLAGL-EENYCRNPDND 484
+C +G +YRG SKT C W+ KY+ E G+ E N+CRNPD D
Sbjct: 191 DCYVDDGYSYRGRVSKTIHQHTCLYWNSHLLLQEKYNMFMEDAEAHGIGEHNFCRNPDGD 250
Query: 485 EKGPWCY--TTDPETRFDYCDIPEC 553
+K PWC+ + + +++YCD+P C
Sbjct: 251 KK-PWCFIKVNNVKVKWEYCDVPAC 274
>ref|XP_886646.1| PREDICTED: similar to Serine protease hepsin (Transmembrane protease,
serine 1) isoform 3 [Bos taurus]
Length = 434
Score = 199 bits (506), Expect = 9e-51
Identities = 131/356 (36%), Positives = 182/356 (51%), Gaps = 26/356 (7%)
Frame = +2
Query: 1496 VAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCD 1675
VAG+ C+E S T G +C D G + ++ CD
Sbjct: 85 VAGLSCEEMGFLRALDFSELDVRTAGANGTSGFFCV-----DEGRLPHARRLLEVLSVCD 139
Query: 1676 IPQ---CVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLIS 1846
P+ TS DCG K+ R+VGG + WPWQVSLRY H CGG+++S
Sbjct: 140 CPRGRFLATSCQDCGHRKLPVD----RIVGGQDTSLGRWPWQVSLRYD-GAHLCGGSVLS 194
Query: 1847 PEWVLTAKHCL-EKSSSPSSYKVILGAHEE---HHLGEGVQEIDVSK---LFKEPSGA-- 1999
+WVLTA HC E++ S ++V GA + H + GVQ + F++P+
Sbjct: 195 RDWVLTAAHCFPERNRVLSRWRVFAGAVAQTSPHGVQLGVQAVIYHGGYLPFRDPNSEEN 254
Query: 2000 --DIALLKLSSPAVITDQVIPACLPTPNYVVADRTACYITGWGETKGTYG--AGLLKEAR 2167
DIAL+ LS +T+ + P CLP + D C +TGWG T+ YG AG+L+EAR
Sbjct: 255 SNDIALVHLSGTLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQEAR 313
Query: 2168 LPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEK----DKYILQG 2335
+P+I N VCN ++ ++ K CAG+ GGID+CQGDSGGP VC + ++ L G
Sbjct: 314 VPIISNDVCNGPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCG 373
Query: 2336 VTSWGLGCALPNKPGVYVRVSRFVTWIEEIM------RRN*SDGKQREVSRDLEAG 2485
+ SWG GCAL KPGVY +VS F WI + + R G+ + R+ EAG
Sbjct: 374 IVSWGTGCALAQKPGVYTKVSDFREWIFQAIKVKFEPRWEPEGGRVWDSEREREAG 429
>ref|XP_584887.2| PREDICTED: similar to Serine protease hepsin (Transmembrane protease,
serine 1) isoform 2 [Bos taurus]
Length = 417
Score = 199 bits (505), Expect = 1e-50
Identities = 125/332 (37%), Positives = 174/332 (52%), Gaps = 20/332 (6%)
Frame = +2
Query: 1496 VAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCD 1675
VAG+ C+E S T G +C D G + ++ CD
Sbjct: 85 VAGLSCEEMGFLRALDFSELDVRTAGANGTSGFFCV-----DEGRLPHARRLLEVLSVCD 139
Query: 1676 IPQ---CVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLIS 1846
P+ TS DCG K+ R+VGG + WPWQVSLRY H CGG+++S
Sbjct: 140 CPRGRFLATSCQDCGHRKLPVD----RIVGGQDTSLGRWPWQVSLRYD-GAHLCGGSVLS 194
Query: 1847 PEWVLTAKHCL-EKSSSPSSYKVILGAHEE---HHLGEGVQEIDVSK---LFKEPSGA-- 1999
+WVLTA HC E++ S ++V GA + H + GVQ + F++P+
Sbjct: 195 RDWVLTAAHCFPERNRVLSRWRVFAGAVAQTSPHGVQLGVQAVIYHGGYLPFRDPNSEEN 254
Query: 2000 --DIALLKLSSPAVITDQVIPACLPTPNYVVADRTACYITGWGETKGTYG--AGLLKEAR 2167
DIAL+ LS +T+ + P CLP + D C +TGWG T+ YG AG+L+EAR
Sbjct: 255 SNDIALVHLSGTLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQEAR 313
Query: 2168 LPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEK----DKYILQG 2335
+P+I N VCN ++ ++ K CAG+ GGID+CQGDSGGP VC + ++ L G
Sbjct: 314 VPIISNDVCNGPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCG 373
Query: 2336 VTSWGLGCALPNKPGVYVRVSRFVTWIEEIMR 2431
+ SWG GCAL KPGVY +VS F WI + ++
Sbjct: 374 IVSWGTGCALAQKPGVYTKVSDFREWIFQAIK 405
>ref|XP_618102.2| PREDICTED: similar to Transmembrane protease, serine 3 [Bos taurus]
Length = 787
Score = 194 bits (493), Expect = 3e-49
Identities = 103/235 (43%), Positives = 139/235 (59%), Gaps = 7/235 (2%)
Frame = +2
Query: 1745 RVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKV---- 1912
R+VGG S WPWQ SL+++ H CGG++I+P WV+TA HC+ P S+ +
Sbjct: 250 RIVGGNTSSLAQWPWQASLQFQGY-HLCGGSVITPLWVVTAAHCVYDLYLPKSWTIQVGL 308
Query: 1913 --ILGAHEEHHLGEGVQEIDVSKLFKEPSGADIALLKLSSPAVITDQVIPACLPTPNYVV 2086
+L + HL E + I SK + G DIAL+KL+ P + P CLP
Sbjct: 309 VSLLDSPAPSHLVEKI--IYHSKYKPKRLGNDIALMKLAGPVTFNEMTQPVCLPNSEENF 366
Query: 2087 ADRTACYITGWGETK-GTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGG 2263
D C+ +GWG T+ G + +L A +P+I NKVCN + G +S LCAG+L GG
Sbjct: 367 PDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKVCNHRDVYGGIISPSMLCAGYLKGG 426
Query: 2264 IDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIM 2428
+DSCQGDSGGPLVC E+ + L G TS+G+GCA NKPGVY R++ F+ WI E M
Sbjct: 427 VDSCQGDSGGPLVCQERRVWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQM 481
>ref|XP_607560.2| PREDICTED: similar to Transmembrane protease, serine 13 (Mosaic
serine protease) (Membrane-type mosaic serine protease)
[Bos taurus]
Length = 683
Score = 193 bits (491), Expect = 5e-49
Identities = 99/231 (42%), Positives = 136/231 (58%), Gaps = 7/231 (3%)
Frame = +2
Query: 1745 RVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLTAKHC--LEKSSSPSSYKVIL 1918
R+VGG + WPWQVSL++ R H CGGTLI +W+LTA HC + + +KV +
Sbjct: 396 RIVGGARAPESKWPWQVSLQFS-RTHICGGTLIDAQWILTAAHCFFITREKILEGWKVYV 454
Query: 1919 GAHEEHHLGEGVQEIDV---SKLFKEPSGADIALLKLSSPAVITDQVIPACLPTPNYVVA 2089
G ++ HHL E + S + DIAL++LS P ++ V PACLP
Sbjct: 455 GTNDLHHLPESASVAQIIINSNYSDDQDDYDIALMRLSKPLTLSAHVHPACLPMHGQTFG 514
Query: 2090 DRTACYITGWGETKGT--YGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGG 2263
C+ITG+G+TK T + L+E ++ +I+ K CN Y D ++ + +CAG L GG
Sbjct: 515 LNEICWITGFGKTKETDERTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGG 574
Query: 2264 IDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWI 2416
DSCQGDSGGPLVC + ++ L GVTSWG GC NKPGVY +V+ + WI
Sbjct: 575 RDSCQGDSGGPLVCEQNGRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWI 625
Database: RefSeqBP
Posted date: Aug 1, 2006 7:14 PM
Number of letters in database: 16,112,626
Number of sequences in database: 33,508
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 107,054,164
Number of Sequences: 33508
Number of extensions: 3243200
Number of successful extensions: 12413
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 8079
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11666
length of database: 16,112,626
effective HSP length: 110
effective length of database: 12,426,746
effective search space used: 9829556086
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqCP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= LVRM1_0045_D02
(2705 letters)
Database: RefSeqCP
33,732 sequences; 19,266,565 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|XP_533468.2| PREDICTED: similar to Plasminogen precursor [Ca... 1444 0.0
Alignment gi|NP_001002964.1| hepatocyte growth factor [Canis familiaris] 503 e-142
Alignment gi|XP_541884.2| PREDICTED: similar to macrophage stimulating 1 ... 491 e-138
Alignment gi|XP_539955.2| PREDICTED: similar to Tissue-type plasminogen a... 258 3e-68
Alignment gi|XP_541697.2| PREDICTED: similar to Serine protease hepsin (T... 206 1e-52
Alignment gi|XP_535016.2| PREDICTED: similar to hyaluronan binding protei... 205 2e-52
Alignment gi|XP_853682.1| PREDICTED: similar to Transmembrane protease, s... 195 2e-49
Alignment gi|XP_861645.1| PREDICTED: hepatocyte growth factor activator i... 194 5e-49
Alignment gi|NP_001026985.1| HGF activator [Canis familiaris] 190 5e-48
Alignment gi|XP_850538.1| PREDICTED: hepatocyte growth factor activator i... 190 7e-48
>ref|XP_533468.2| PREDICTED: similar to Plasminogen precursor [Canis familiaris]
Length = 812
Score = 1444 bits (3738), Expect = 0.0
Identities = 651/812 (80%), Positives = 717/812 (88%), Gaps = 3/812 (0%)
Frame = +2
Query: 11 MDHKEVVXXXXXXXXXXXXXXXXXYVNTQGAFLFSLSRKQVAARSVEECAAKCEAETNFI 190
M+HKEVV YVNTQGA +FSL++KQ++ S+EECAAKCE ET FI
Sbjct: 1 MEHKEVVLLLLLFLKSGHGSLLDDYVNTQGASVFSLTKKQLSVGSIEECAAKCEEETGFI 60
Query: 191 CRAFQYHSKDQQCVVMAENSKTSPIARMRDVVLFEKRIYLSECKTGNGKNYRGTTSKTKS 370
CR+FQYHSK+QQCV+M ENSK+S + RMRDV LFEKRIYLSECKTGNGK YRGT +KTK+
Sbjct: 61 CRSFQYHSKEQQCVIMPENSKSSIVFRMRDVFLFEKRIYLSECKTGNGKTYRGTMAKTKN 120
Query: 371 GVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRNPDNDEKGPWCYTTDPETRFDYCDIPE 550
V CQKWS +SPH P Y+PEK PL GLEENYCRNPDNDE GPWCYTT+P+ RFDYC+IPE
Sbjct: 121 DVACQKWSDNSPHKPNYTPEKHPLEGLEENYCRNPDNDENGPWCYTTNPDVRFDYCNIPE 180
Query: 551 CEDECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGE 730
CE+ECMHCSGE+YEGKISKT SG+ECQ+W SQ+PHAHGY+PSKFP+KNLKMNYCRNPDGE
Sbjct: 181 CEEECMHCSGENYEGKISKTKSGLECQAWNSQTPHAHGYIPSKFPSKNLKMNYCRNPDGE 240
Query: 731 PRPWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVTASGHTCQRWS 910
PRPWCFT DPNKRWEFCDIPRCTTPPP SGPTYQCLKGRGE+YRG VSVT SGHTCQ WS
Sbjct: 241 PRPWCFTMDPNKRWEFCDIPRCTTPPPPSGPTYQCLKGRGESYRGKVSVTVSGHTCQHWS 300
Query: 911 AQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVRWDYCKIPSCGSSTTSTE 1090
Q+PHKHNRTPENFPCKNL+ENYCRNPDGETAPWCYTT+SEVRW++C+IPSC SS +TE
Sbjct: 301 EQTPHKHNRTPENFPCKNLDENYCRNPDGETAPWCYTTNSEVRWEHCQIPSCESSPITTE 360
Query: 1091 HLDAP--VPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPN 1264
+LDAP VPPEQTPV Q+CY GNG+SYRGTSSTTITGRKCQSW SMTPHRHEKTP +FP
Sbjct: 361 YLDAPASVPPEQTPVVQECYHGNGQSYRGTSSTTITGRKCQSWSSMTPHRHEKTPEHFPE 420
Query: 1265 AGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLS- 1441
AGLTMNYCRNPDADKSPWCYTTDP VRWE+CNL+KC + E TN PA+ QVPS ++ S
Sbjct: 421 AGLTMNYCRNPDADKSPWCYTTDPSVRWEFCNLRKCLDPEASATNSPAVPQVPSGQEPSA 480
Query: 1442 EDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDD 1621
DCMFGNGK YRGK+ATTV G+PCQEWAAQEPHRHSIFTPETNP+AGLEKNYCRNPDGD
Sbjct: 481 SDCMFGNGKGYRGKKATTVMGIPCQEWAAQEPHRHSIFTPETNPQAGLEKNYCRNPDGDV 540
Query: 1622 NGPWCYTTNPQKLFDYCDIPQCVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSL 1801
NGPWCYT N +KLFDYCD+PQCV++SFDCGKP+VEPKKCP RVVGGCV+ PHSWPWQ+SL
Sbjct: 541 NGPWCYTMNQRKLFDYCDVPQCVSTSFDCGKPQVEPKKCPGRVVGGCVANPHSWPWQISL 600
Query: 1802 RYRYRGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLF 1981
R RY HFCGGTLISPEWVLTA HCLE+SS P+SYKVILGAH+E +L VQEI+V KLF
Sbjct: 601 RTRYGKHFCGGTLISPEWVLTAAHCLERSSRPASYKVILGAHKEVNLESDVQEIEVYKLF 660
Query: 1982 KEPSGADIALLKLSSPAVITDQVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLKE 2161
EP+ ADIALLKLSSPAVIT +VIPACLP PNYVVADRT CYITGWGET+GTYGAGLLKE
Sbjct: 661 LEPTRADIALLKLSSPAVITSKVIPACLPPPNYVVADRTLCYITGWGETQGTYGAGLLKE 720
Query: 2162 ARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVT 2341
A+LPVIENKVCNRYEYL+G+V S ELCAG+LAGG DSCQGDSGGPLVCFEKDKYILQGVT
Sbjct: 721 AQLPVIENKVCNRYEYLNGRVKSTELCAGNLAGGTDSCQGDSGGPLVCFEKDKYILQGVT 780
Query: 2342 SWGLGCALPNKPGVYVRVSRFVTWIEEIMRRN 2437
SWGLGCA PNKPGVYVRVSRFVTWIE IMR N
Sbjct: 781 SWGLGCARPNKPGVYVRVSRFVTWIEGIMRNN 812
>ref|NP_001002964.1| hepatocyte growth factor [Canis familiaris]
Length = 730
Score = 503 bits (1295), Expect = e-142
Identities = 264/651 (40%), Positives = 361/651 (55%), Gaps = 21/651 (3%)
Frame = +2
Query: 539 DIPECEDECMHC---SGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNY 709
D+ E +D +C G Y+G +S T SGI+CQ W S PH H +LPS + K+L+ NY
Sbjct: 117 DLYENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENY 176
Query: 710 CRNPDGEPR-PWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVTAS 886
CRNP GE PWCFT++P R+E CDIP+C+ +C+ GE+YRG + T S
Sbjct: 177 CRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSE--------VECMTCNGESYRGPMDHTES 228
Query: 887 GHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVRWDYCKIPSC 1066
G CQRW Q+PH+H PE +P K ++NYCRNPDG+ PWCYT D + W+YC I C
Sbjct: 229 GKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMC 288
Query: 1067 GSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKT 1246
ST + D VP E T +C +G GE YRGT +T G CQ W S PH+H+ T
Sbjct: 289 AHSTMN----DTDVPMETT----ECIQGQGEGYRGTINTIWNGVPCQRWDSQYPHQHDIT 340
Query: 1247 PGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPS 1426
P NF L NYCRNPD +SPWC+TTDP +R YC+ Q+P
Sbjct: 341 PENFKCKDLRENYCRNPDGAESPWCFTTDPNIRVGYCS------------------QIPK 382
Query: 1427 VEDLS-EDCMFGNGKRYRGKRATTVAGVPCQEWAA--QEPHRHSIFTPETNPRAGLEKNY 1597
+ S +DC GNGK Y G + T +G+ C W ++ HRH + P+ + L KNY
Sbjct: 383 CDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWEKNMEDLHRHIFWEPDASK---LNKNY 439
Query: 1598 CRNPDGDDNGPWCYTTNPQKLFDYCDIPQCVTSS-----------FDCGKPKVEPKKCPA 1744
CRNPD D +GPWCYT NP +DYC I +C + C K K
Sbjct: 440 CRNPDDDAHGPWCYTGNPLIPWDYCPIFRCEGDTTPTIVNLDHPVISCAKTK------QL 493
Query: 1745 RVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLTAKHCL-EKSSSPSSYKVILG 1921
RVV G + + W VSL+YR + H CGG+LI W+LTA+ C ++ Y+ LG
Sbjct: 494 RVVNG-IPTRTNVGWMVSLKYRNK-HICGGSLIKESWILTARQCFPSRNRDLKDYEAWLG 551
Query: 1922 AHEEHHLGEGV--QEIDVSKLFKEPSGADIALLKLSSPAVITDQVIPACLPTPNYVVADR 2095
H+ H G+ Q ++VS+L P G+D+ LLKL+ PA++ D V LP + ++
Sbjct: 552 IHDVHGKGDEKRKQVLNVSQLVYGPEGSDLVLLKLARPAILDDFVSTIDLPNYGCTIPEK 611
Query: 2096 TACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSC 2275
T C + GWG T GLL+ A L ++ N+ C++Y ++ E+CAG C
Sbjct: 612 TTCSVYGWGYTGSINFDGLLRVAHLYIMGNEKCSQYHQGKVTLNESEICAGAENIVSGPC 671
Query: 2276 QGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIM 2428
+GD GGPLVC + ++ GV G GCA+PN+PG++VRV+ + WI +I+
Sbjct: 672 EGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 722
Score = 397 bits (1021), Expect = e-110
Identities = 187/440 (42%), Positives = 256/440 (58%), Gaps = 12/440 (2%)
Frame = +2
Query: 116 LSRKQVAARSVEECAAKCEAETN--FICRAFQYHSKDQQCVVMAENSKTSPIARM--RDV 283
L K + ++CA +C F C+AF + ++C+ NS TS + + +
Sbjct: 57 LKIKTKKMNTADQCANRCIRNKGLPFTCKAFVFDKARKRCLWFPFNSMTSGVKKEFGHEF 116
Query: 284 VLFEKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENY 463
L+E + Y+ C G G +Y+GT S TKSG+ CQ W+ PH + P + L+ENY
Sbjct: 117 DLYENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENY 176
Query: 464 CRNPDNDEKGPWCYTTDPETRFDYCDIPECED-ECMHCSGEHYEGKISKTMSGIECQSWG 640
CRNP +E GPWC+T++PE R++ CDIP+C + ECM C+GE Y G + T SG CQ W
Sbjct: 177 CRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGPMDHTESGKICQRWD 236
Query: 641 SQSPHAHGYLPSKFPNKNLKMNYCRNPDGEPRPWCFTTDPNKRWEFCDIPRC--TTPPPT 814
Q+PH H +LP ++P+K NYCRNPDG+PRPWC+T DP+ WE+C I C +T T
Sbjct: 237 HQTPHRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMCAHSTMNDT 296
Query: 815 SGP--TYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRN 988
P T +C++G+GE YRGT++ +G CQRW +Q PH+H+ TPENF CK+L ENYCRN
Sbjct: 297 DVPMETTECIQGQGEGYRGTINTIWNGVPCQRWDSQYPHQHDITPENFKCKDLRENYCRN 356
Query: 989 PDGETAPWCYTTDSEVRWDYC-KIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESY 1165
PDG +PWC+TTD +R YC +IP C S+ QDCYRGNG++Y
Sbjct: 357 PDGAESPWCFTTDPNIRVGYCSQIPKCDVSS-----------------GQDCYRGNGKNY 399
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDAD-KSPWCYTTDPRV 1342
G S T +G C W H + L NYCRNPD D PWCYT +P +
Sbjct: 400 MGNLSKTRSGLTCSMWEKNMEDLHRHIFWEPDASKLNKNYCRNPDDDAHGPWCYTGNPLI 459
Query: 1343 RWEYCNLKKC-SETEQQVTN 1399
W+YC + +C +T + N
Sbjct: 460 PWDYCPIFRCEGDTTPTIVN 479
>ref|XP_541884.2| PREDICTED: similar to macrophage stimulating 1 (hepatocyte growth
factor-like) [Canis familiaris]
Length = 712
Score = 491 bits (1264), Expect = e-138
Identities = 260/659 (39%), Positives = 357/659 (54%), Gaps = 23/659 (3%)
Frame = +2
Query: 524 RFDYCDIPECED---ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKN 694
R +CD+ + +D C+ +G Y G ++ T G+ CQ W + P+ H Y P+
Sbjct: 95 RSGHCDLFQKKDYVRTCITDNGVKYRGTVAITTGGLPCQHWSHRFPNDHKYTPTL--RNG 152
Query: 695 LKMNYCRNPDGEPR-PWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTV 871
L+ N+CRNPD +P PWC+TTDP R++ C I C C+ GE+YRG V
Sbjct: 153 LEENFCRNPDRDPGGPWCYTTDPAVRFQSCGIKSCREAA--------CVWCNGEDYRGAV 204
Query: 872 SVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVRWDYC 1051
T SG CQRW Q PH H P F K+L++NYCRNPDG PWCYTTD +V ++C
Sbjct: 205 DRTQSGRECQRWDLQHPHAHPFEPGKFLDKDLDDNYCRNPDGSERPWCYTTDPQVEREFC 264
Query: 1052 KIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPH 1231
+ CGS P +C+RG GE YRGT++TT G CQ W + PH
Sbjct: 265 DLTRCGSEAQ----------PRHESTTLNCFRGKGEGYRGTANTTAAGVPCQRWDAQKPH 314
Query: 1232 RHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYC-NLKKCSETEQQVTNFPA 1408
+H P + L N+CRNPD ++PWC+T+ P +R +C + +C++ +
Sbjct: 315 QHRFAPEKYACKDLRENFCRNPDGSEAPWCFTSRPGMRVAFCYQIPRCADDVRP------ 368
Query: 1409 IAQVPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLE 1588
EDC G G+RYRG + T GVPCQ W+A+ PH+ FT + P A LE
Sbjct: 369 -----------EDCYNGVGERYRGSVSRTRKGVPCQHWSAEMPHKPQ-FTAISAPDAHLE 416
Query: 1589 KNYCRNPDGDDNGPWCYTTNPQKLFDYCDIPQCVTSS------------FD-CGK--PKV 1723
+N+CRNPD D +GPWCYTT+P FDYC + +C F+ CGK ++
Sbjct: 417 ENFCRNPDRDSHGPWCYTTDPGTPFDYCALRRCDDDQPPSILEPPDQVVFEKCGKRVTRL 476
Query: 1724 EPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLTAKHCLEKSSSP-S 1900
+ ++ RVVGG P + PW VSLR R HFCGG+L+ +WVLTA+ C P
Sbjct: 477 DQQRSKLRVVGGQ---PGNSPWTVSLRNRQGQHFCGGSLVKEQWVLTARQCFSSCHVPLM 533
Query: 1901 SYKVILGA-HEEHHLGE-GVQEIDVSKLFKEPSGADIALLKLSSPAVITDQVIPACLPTP 2074
Y+V LG + GE G+Q+I V+K+ PSG+ + LLKL P + +V CLP
Sbjct: 534 GYEVWLGTLFQNPQPGEPGLQQIPVAKMVCGPSGSQLVLLKLERPVTLNQRVALICLPPE 593
Query: 2075 NYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHL 2254
YVV T C I GWGETKGT +L A L VI N+ CN G++ E+C L
Sbjct: 594 RYVVPPGTKCEIAGWGETKGTGNNKVLNVASLNVISNQECNIKH--RGRIRENEMCTEGL 651
Query: 2255 AGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIMR 2431
+ +C+GD GGPL CF D ++L+G+ CA P P +++RVS F WI ++M+
Sbjct: 652 LAPVGACEGDYGGPLACFTHDCWVLEGIIIPNRVCARPRWPAIFMRVSVFTDWIHKVMQ 710
Score = 398 bits (1022), Expect = e-110
Identities = 197/432 (45%), Positives = 250/432 (57%), Gaps = 7/432 (1%)
Frame = +2
Query: 149 EECAAKCEAETNFICRAFQYHSKDQQCVVM--AENSKTSPIARMRDVVLFEKRIYLSECK 322
EECA +C + CRAF Y+ C ++ + S + + R LF+K+ Y+ C
Sbjct: 55 EECAGRCGPLLD--CRAFHYNVSSHGCQLLPWTQYSPYTELQRSGHCDLFQKKDYVRTCI 112
Query: 323 TGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRNPDNDEKGPWC 502
T NG YRGT + T G+ CQ WS P+ KY+P GLEEN+CRNPD D GPWC
Sbjct: 113 TDNGVKYRGTVAITTGGLPCQHWSHRFPNDHKYTPTL--RNGLEENFCRNPDRDPGGPWC 170
Query: 503 YTTDPETRFDYCDIPEC-EDECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSK 679
YTTDP RF C I C E C+ C+GE Y G + +T SG ECQ W Q PHAH + P K
Sbjct: 171 YTTDPAVRFQSCGIKSCREAACVWCNGEDYRGAVDRTQSGRECQRWDLQHPHAHPFEPGK 230
Query: 680 FPNKNLKMNYCRNPDGEPRPWCFTTDPNKRWEFCDIPRC--TTPPPTSGPTYQCLKGRGE 853
F +K+L NYCRNPDG RPWC+TTDP EFCD+ RC P T C +G+GE
Sbjct: 231 FLDKDLDDNYCRNPDGSERPWCYTTDPQVEREFCDLTRCGSEAQPRHESTTLNCFRGKGE 290
Query: 854 NYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSE 1033
YRGT + TA+G CQRW AQ PH+H PE + CK+L EN+CRNPDG APWC+T+
Sbjct: 291 GYRGTANTTAAGVPCQRWDAQKPHQHRFAPEKYACKDLRENFCRNPDGSEAPWCFTSRPG 350
Query: 1034 VRWDYC-KIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQS 1210
+R +C +IP C V PE DCY G GE YRG+ S T G CQ
Sbjct: 351 MRVAFCYQIPRCADD----------VRPE------DCYNGVGERYRGSVSRTRKGVPCQH 394
Query: 1211 WVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADK-SPWCYTTDPRVRWEYCNLKKCSETEQ 1387
W + PH+ + T + P+A L N+CRNPD D PWCYTTDP ++YC L++C + +
Sbjct: 395 WSAEMPHKPQFTAISAPDAHLEENFCRNPDRDSHGPWCYTTDPGTPFDYCALRRCDDDQP 454
Query: 1388 QVTNFPAIAQVP 1423
P+I + P
Sbjct: 455 -----PSILEPP 461
>ref|XP_539955.2| PREDICTED: similar to Tissue-type plasminogen activator precursor
(tPA) (t-PA) (t-plasminogen activator) [Canis familiaris]
Length = 560
Score = 258 bits (658), Expect = 3e-68
Identities = 161/462 (34%), Positives = 232/462 (50%), Gaps = 31/462 (6%)
Frame = +2
Query: 1139 CYRGNGESYRGTSSTTITGRKCQSW----VSMTPHRHEKTPGNFPNAGLTMNYCRNPDAD 1306
CY+ G SYRGT ST +G +C +W +++ P+ + G + NYCRNPD D
Sbjct: 124 CYKDQGISYRGTWSTAESGAECANWNSSALALKPYSARRPHAVRLGLG-SHNYCRNPDGD 182
Query: 1307 KSPWCYTTDP-RVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSEDCMFGNGKRYRGK 1483
PWCY + E+C+ C + + +EDC FG G YRG
Sbjct: 183 LRPWCYVFKAGKYSTEFCSTPACPKEK------------------NEDCYFGKGLAYRGT 224
Query: 1484 RATTVAGVPCQEWAAQEPHRHSIFTPETNPRA-GL-EKNYCRNPDGDDNGPWCYTTNPQK 1657
+ T +G PC W ++ T +TN +A GL NYCRNPDGD PWC+ +K
Sbjct: 225 YSFTTSGTPCLPWNSRVLAGKFYTTWKTNAQALGLGSHNYCRNPDGDAK-PWCHVLKDRK 283
Query: 1658 L-FDYCDIPQCVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGH---- 1822
L ++YCD+PQC T CG K+ R+ GG + S PWQ ++ + R
Sbjct: 284 LTWEYCDVPQCST----CGLRHY--KQPQFRIKGGLYADITSHPWQAAIFVKNRRSPGER 337
Query: 1823 -FCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLFKEPS-- 1993
FCGG LIS WVL+A HC ++ P KV+LG GE Q+ +V K
Sbjct: 338 FFCGGILISSCWVLSAAHCFQERYPPHQLKVVLGRTYREVPGEKEQKFEVEKYITHKEFD 397
Query: 1994 ----GADIALLKLSSPAVI----TDQVIPACLPTPNYVVADRTACYITGWG--ETKGTYG 2143
DIALLKL S ++ +D V ACLP + + D T C ++G+G E +
Sbjct: 398 DDTYNNDIALLKLQSDSLHCAQESDAVRTACLPEADLQLPDWTECELSGYGKHEASSPFY 457
Query: 2144 AGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGG------IDSCQGDSGGPLVC 2305
+ LKEA + + + C + +++ LCAG G D+CQGDSGGPLVC
Sbjct: 458 SERLKEAHVRLYPSSRCTSRHLFNKTITNNMLCAGDTRSGGNQANLHDACQGDSGGPLVC 517
Query: 2306 FEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIMR 2431
+ ++ L G+ SWG+GC + PG+Y +V+ ++ WI++ M+
Sbjct: 518 MKDNRMTLVGIISWGIGCGQKDVPGIYTKVTNYLDWIQDNMQ 559
Score = 119 bits (297), Expect = 2e-26
Identities = 79/252 (31%), Positives = 111/252 (44%), Gaps = 26/252 (10%)
Frame = +2
Query: 698 KMNYCRNPDGEPR-----------PWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQ---- 832
++ YCR G P+ P CF ++ + C P G +
Sbjct: 62 RVEYCRCAGGRPQCHSVPVRGCSEPRCFNGGTCRQALYFADFVCQCPEGFLGKRCEIDAG 121
Query: 833 --CLKGRGENYRGTVSVTASGHTCQRWSAQS----PHKHNRTPENFPCKNLEENYCRNPD 994
C K +G +YRGT S SG C W++ + P+ R P NYCRNPD
Sbjct: 122 ATCYKDQGISYRGTWSTAESGAECANWNSSALALKPYSARR-PHAVRLGLGSHNYCRNPD 180
Query: 995 GETAPWCYTTDS-EVRWDYCKIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRG 1171
G+ PWCY + + ++C P+C P E+ +DCY G G +YRG
Sbjct: 181 GDLRPWCYVFKAGKYSTEFCSTPAC--------------PKEKN---EDCYFGKGLAYRG 223
Query: 1172 TSSTTITGRKCQSWVS--MTPHRHEKTPGNFPNAGL-TMNYCRNPDADKSPWCYT-TDPR 1339
T S T +G C W S + + N GL + NYCRNPD D PWC+ D +
Sbjct: 224 TYSFTTSGTPCLPWNSRVLAGKFYTTWKTNAQALGLGSHNYCRNPDGDAKPWCHVLKDRK 283
Query: 1340 VRWEYCNLKKCS 1375
+ WEYC++ +CS
Sbjct: 284 LTWEYCDVPQCS 295
Score = 114 bits (286), Expect = 4e-25
Identities = 72/208 (34%), Positives = 91/208 (43%), Gaps = 18/208 (8%)
Frame = +2
Query: 536 CDIPE------CEDE----CMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFP 685
C PE CE + C G Y G S SG EC +W S + Y +
Sbjct: 105 CQCPEGFLGKRCEIDAGATCYKDQGISYRGTWSTAESGAECANWNSSALALKPYSARRPH 164
Query: 686 NKNLKM---NYCRNPDGEPRPWCFTTDPNK-RWEFCDIPRCTTPPPTSGPTYQCLKGRGE 853
L + NYCRNPDG+ RPWC+ K EFC P C C G+G
Sbjct: 165 AVRLGLGSHNYCRNPDGDLRPWCYVFKAGKYSTEFCSTPAC-----PKEKNEDCYFGKGL 219
Query: 854 NYRGTVSVTASGHTCQRWSAQ--SPHKHNRTPENFPCKNL-EENYCRNPDGETAPWCYT- 1021
YRGT S T SG C W+++ + + N L NYCRNPDG+ PWC+
Sbjct: 220 AYRGTYSFTTSGTPCLPWNSRVLAGKFYTTWKTNAQALGLGSHNYCRNPDGDAKPWCHVL 279
Query: 1022 TDSEVRWDYCKIPSCGSSTTSTEHLDAP 1105
D ++ W+YC +P C ST H P
Sbjct: 280 KDRKLTWEYCDVPQC--STCGLRHYKQP 305
Score = 114 bits (285), Expect = 5e-25
Identities = 64/174 (36%), Positives = 84/174 (48%), Gaps = 12/174 (6%)
Frame = +2
Query: 317 CKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYS---PEKFPLAGLEENYCRNPDNDE 487
C G +YRGT S +SG C W+ S+ + YS P L NYCRNPD D
Sbjct: 124 CYKDQGISYRGTWSTAESGAECANWNSSALALKPYSARRPHAVRLGLGSHNYCRNPDGDL 183
Query: 488 KGPWCYTTDP-ETRFDYCDIPEC----EDECMHCSGEHYEGKISKTMSGIECQSWGSQSP 652
+ PWCY + ++C P C ++C G Y G S T SG C W S+
Sbjct: 184 R-PWCYVFKAGKYSTEFCSTPACPKEKNEDCYFGKGLAYRGTYSFTTSGTPCLPWNSRVL 242
Query: 653 HAHGYLPSKFPNKNLKM---NYCRNPDGEPRPWCFTTDPNK-RWEFCDIPRCTT 802
Y K + L + NYCRNPDG+ +PWC K WE+CD+P+C+T
Sbjct: 243 AGKFYTTWKTNAQALGLGSHNYCRNPDGDAKPWCHVLKDRKLTWEYCDVPQCST 296
Score = 64.3 bits (155), Expect = 6e-10
Identities = 37/97 (38%), Positives = 47/97 (48%), Gaps = 4/97 (4%)
Frame = +2
Query: 314 ECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGL---EENYCRNPDND 484
+C G G YRGT S T SG C W+ Y+ K L NYCRNPD D
Sbjct: 212 DCYFGKGLAYRGTYSFTTSGTPCLPWNSRVLAGKFYTTWKTNAQALGLGSHNYCRNPDGD 271
Query: 485 EKGPWCYT-TDPETRFDYCDIPECEDECMHCSGEHYE 592
K PWC+ D + ++YCD+P+C C HY+
Sbjct: 272 AK-PWCHVLKDRKLTWEYCDVPQCST----CGLRHYK 303
>ref|XP_541697.2| PREDICTED: similar to Serine protease hepsin (Transmembrane protease,
serine 1) [Canis familiaris]
Length = 417
Score = 206 bits (524), Expect = 1e-52
Identities = 128/332 (38%), Positives = 177/332 (53%), Gaps = 20/332 (6%)
Frame = +2
Query: 1496 VAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCD 1675
VAG+ C+E HS T G +C D G ++ CD
Sbjct: 85 VAGLSCEEMGFLRALGHSELDVRTAGANGTSGFFCV-----DEGRLPLARRLLEVISVCD 139
Query: 1676 IPQ---CVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLIS 1846
P+ T DCG+ K+ R+VGG + WPWQVSLRY H CGG+L+S
Sbjct: 140 CPRGRFLATVCQDCGRRKLPVD----RIVGGQDTSLGRWPWQVSLRYD-GAHLCGGSLLS 194
Query: 1847 PEWVLTAKHCL-EKSSSPSSYKVILGAHEE---HHLGEGVQEIDVSK---LFKEPSGA-- 1999
+WVLTA HC E++ S ++V GA + H L GVQ + F++P+
Sbjct: 195 GDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEEN 254
Query: 2000 --DIALLKLSSPAVITDQVIPACLPTPNYVVADRTACYITGWGETKGTYG--AGLLKEAR 2167
DIAL+ LSSP +T+ + P CLP + D C +TGWG T+ YG AG+L+EAR
Sbjct: 255 SNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQEAR 313
Query: 2168 LPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEK----DKYILQG 2335
+P+I N++CN ++ ++ K CAG+ GGID+CQGDSGGP VC + ++ L G
Sbjct: 314 VPIISNELCNGPDFYANQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCG 373
Query: 2336 VTSWGLGCALPNKPGVYVRVSRFVTWIEEIMR 2431
+ SWG GCAL KPGVY +VS F WI + ++
Sbjct: 374 IVSWGTGCALAQKPGVYTKVSDFREWIFQAIK 405
>ref|XP_535016.2| PREDICTED: similar to hyaluronan binding protein 2 [Canis familiaris]
Length = 565
Score = 205 bits (521), Expect = 2e-52
Identities = 168/538 (31%), Positives = 235/538 (43%), Gaps = 52/538 (9%)
Frame = +2
Query: 977 YCRNPDGETAPWCYTTDSEVRWDYCKIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNG 1156
Y NPD W YT D D C+ C EH DC NG
Sbjct: 69 YPENPD-----WYYTED-----DPCQSNPC-------EH------------GGDCLV-NG 98
Query: 1157 ESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMN------YCRNPDADKSPW 1318
E++ + +G +CQ+ ++ ++ P + +T + CR+P K P
Sbjct: 99 ENFTCSCPVPFSGNRCQN----VQNKCKENPCDRGECLITQSPPYYHCACRHPY--KGPD 152
Query: 1319 CYTTDPRVRWEYC-NLKKCSETEQQ---VTNFPAIAQVPSVEDLSEDCMFGNGKRYRGKR 1486
C P R C N CS ++ P + E +DC G+G YRGK
Sbjct: 153 CSRAVPVCRPNPCQNGGTCSRQRRRSKFTCTCPDQFKGKFCEIGPDDCYVGDGYSYRGKV 212
Query: 1487 ATTVAGVPCQEWAAQE--PHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCY--TTNPQ 1654
+ TV C W + ++IF + E N+CRNPDGD PWC+ N +
Sbjct: 213 SKTVNQHSCLYWNSHLLLHENYNIFMEDAEAHGIGEHNFCRNPDGDKK-PWCFIKANNAK 271
Query: 1655 KLFDYCDIPQCVTSSFDCGKP------------------KVEPKKCPARVVGGCVSIPHS 1780
++YCD+ C S+ D P + E K R+ GG S
Sbjct: 272 LKWEYCDVSAC--SALDIADPEGSLTEPLTKLPGFDSCGRTEMTKKVKRIYGGFKSTAGK 329
Query: 1781 WPWQVSLRYRY-------RGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHH 1939
PWQ SL+ +GHFCGG LI P WVLTA HC + + V+LG +
Sbjct: 330 HPWQASLQTSLPLTVSMPQGHFCGGALIHPCWVLTAAHCTNIKARHLT--VVLGDQDLKK 387
Query: 1940 LGEGVQEIDVSKLFK--------EPSGADIALLKLSSP----AVITDQVIPACLPTPNYV 2083
Q V K+FK E DIALLKL A+ + V CLP N
Sbjct: 388 TEFHEQRFGVEKIFKYSLYNEREEIPHNDIALLKLKPVDGHCALESKYVKTVCLP--NSA 445
Query: 2084 VADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAG- 2260
T C+I+GWG T+ G+ L +A++ +I N +CN + D + +CAG+L
Sbjct: 446 FPSGTECHISGWGVTETGEGSRQLLDAKVRLIANTLCNSRQLYDHMIGDSMICAGNLQKP 505
Query: 2261 GIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIMRR 2434
G DSCQGDSGGPL C + Y + G+ SWGL C KPGVY +V++F+ WI+ +++
Sbjct: 506 GQDSCQGDSGGPLTCEKNGTYYVYGIVSWGLECG--KKPGVYTQVAKFLNWIKATIQK 561
Score = 80.9 bits (198), Expect = 6e-15
Identities = 70/275 (25%), Positives = 110/275 (40%), Gaps = 30/275 (10%)
Frame = +2
Query: 413 PKYSPEKFPLAGLEENYCRNPDNDEKGPWCYTTDPETRFDYCDIPECED--ECMHCSGEH 586
P Y + + EE+ R E W YT D D C CE +C+ +GE+
Sbjct: 47 PDYYEDSYEYHNQEEDVNRTAAYPENPDWYYTED-----DPCQSNPCEHGGDCL-VNGEN 100
Query: 587 YEGKISKTMSGIECQSWGS---------------QSP---HAHGYLPSKFPNKNLKMNYC 712
+ SG CQ+ + QSP H P K P+ + + C
Sbjct: 101 FTCSCPVPFSGNRCQNVQNKCKENPCDRGECLITQSPPYYHCACRHPYKGPDCSRAVPVC 160
Query: 713 RNPDGEPRPWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQ-----CLKGRGENYRGTVSV 877
R + C + +R +F CT P G + C G G +YRG VS
Sbjct: 161 RPNPCQNGGTC--SRQRRRSKFT----CTCPDQFKGKFCEIGPDDCYVGDGYSYRGKVSK 214
Query: 878 TASGHTCQRWSAQS--PHKHNRTPENFPCKNL-EENYCRNPDGETAPWCY--TTDSEVRW 1042
T + H+C W++ +N E+ + E N+CRNPDG+ PWC+ +++++W
Sbjct: 215 TVNQHSCLYWNSHLLLHENYNIFMEDAEAHGIGEHNFCRNPDGDKKPWCFIKANNAKLKW 274
Query: 1043 DYCKIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYR 1147
+YC + +C + + P + P C R
Sbjct: 275 EYCDVSACSALDIADPEGSLTEPLTKLPGFDSCGR 309
Score = 56.2 bits (134), Expect = 2e-07
Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 5/85 (5%)
Frame = +2
Query: 314 ECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYS--PEKFPLAGL-EENYCRNPDND 484
+C G+G +YRG SKT + C W+ Y+ E G+ E N+CRNPD D
Sbjct: 199 DCYVGDGYSYRGKVSKTVNQHSCLYWNSHLLLHENYNIFMEDAEAHGIGEHNFCRNPDGD 258
Query: 485 EKGPWCY--TTDPETRFDYCDIPEC 553
+K PWC+ + + +++YCD+ C
Sbjct: 259 KK-PWCFIKANNAKLKWEYCDVSAC 282
>ref|XP_853682.1| PREDICTED: similar to Transmembrane protease, serine 3 (Serine
protease TADG-12) (Tumor associated
differentially-expressed gene-12 protein) [Canis
familiaris]
Length = 513
Score = 195 bits (495), Expect = 2e-49
Identities = 108/257 (42%), Positives = 146/257 (56%), Gaps = 16/257 (6%)
Frame = +2
Query: 1706 CGKPKVEPKKCPA---------RVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWV 1858
C +V KC A R+VGG S WPWQ SL+++ H CGG++I+P WV
Sbjct: 192 CASGRVVTLKCTACGLRMGYSSRIVGGNASSLTQWPWQASLQFQGY-HLCGGSVITPVWV 250
Query: 1859 LTAKHCLEKSSSPSSYKV------ILGAHEEHHLGEGVQEIDVSKLFKEPSGADIALLKL 2020
+TA HC+ P S+ V +L + HL E + I SK + G DIAL+KL
Sbjct: 251 VTAAHCVYDLYVPKSWTVQVGLVSLLDSPAPSHLVEKI--IYHSKYKPKRLGNDIALMKL 308
Query: 2021 SSPAVITDQVIPACLPTPNYVVADRTACYITGWGETK-GTYGAGLLKEARLPVIENKVCN 2197
+ P +++ P CLP D C+ +GWG T+ G + L A +P+I NK+CN
Sbjct: 309 AGPVPFNERIQPVCLPNSEENFPDGKMCWTSGWGATEDGGDASPDLNHAAVPLISNKICN 368
Query: 2198 RYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKP 2377
+ G +S LCAG+L GG+DSCQGDSGGPLVC E+ + L G TS+G+GCA NKP
Sbjct: 369 HRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERRVWKLVGATSFGIGCADVNKP 428
Query: 2378 GVYVRVSRFVTWIEEIM 2428
GVY R++ F+ WI E M
Sbjct: 429 GVYTRITSFLDWIHEQM 445
>ref|XP_861645.1| PREDICTED: hepatocyte growth factor activator isoform 2 [Canis
familiaris]
Length = 657
Score = 194 bits (492), Expect = 5e-49
Identities = 168/595 (28%), Positives = 244/595 (41%), Gaps = 56/595 (9%)
Frame = +2
Query: 806 PPTSGPTYQCLKGRGENY--RGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENY 979
P TS P Q +GRG R S+++ G Q R P + + L
Sbjct: 66 PATSAPEAQGPRGRGLTPPPRAAPSISSPGDPVLTVDGQPC----RFPFRYGGRMLHA-- 119
Query: 980 CRNPDGETAPWCYTT---DSEVRWDYC-KIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYR 1147
C + WC TT D + W YC + P+ T LD+ +
Sbjct: 120 CTSEGSAHRKWCATTHNYDRDRAWGYCVQAPAPPGGQTGPSALDSCASSPCLNGGSCSHT 179
Query: 1148 GNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPD-ADKSPWCY 1324
+ SY T TGR C + R+E A ++ + A C
Sbjct: 180 QDPGSYHCTCPMAFTGRNCDTEKCFDETRYEHLEAGDRWARVSQGQVEQCECAGGQIRCE 239
Query: 1325 TT-------DPRVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSEDCMFGNGKRYRGK 1483
T P + C+L + T ++ ++ S+ C GNG YRG
Sbjct: 240 GTRHTACLSSPCLNGGTCHLIVATGTTVCSCPPGHAGRLCNIVP-SQRCFVGNGTEYRGV 298
Query: 1484 RATTVAGVPCQEWAA----QEPHRHSIFTPETNPRAGLEKN-YCRNPDGDDNGPWCYTTN 1648
+T +G+ C W + QE H S+ GL + YCRNPD D+ PWCY
Sbjct: 299 ASTAASGLSCLAWNSDLLYQELHVDSVGAAAL---LGLGPHAYCRNPDKDER-PWCYVVK 354
Query: 1649 PQKL-FDYCDIPQC--------VTSSF-------------DCGKPKVEPKKCPARVVGGC 1762
L ++YC + C +T++ CGK + R++GG
Sbjct: 355 DSALSWEYCRLAACESLARIPSLTTAVLLSQAEPAPVGRQTCGKRHKKRTFLRPRIIGGS 414
Query: 1763 VSIPHSWPWQVSLRYRYRGH-FCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHH 1939
S+P S PW ++ Y G FC G+L+ WV++A HC S S V+LG H +
Sbjct: 415 SSLPGSHPWLAAI---YIGDSFCAGSLVHTCWVVSAAHCFSNSPRRESVLVVLGQHFFNQ 471
Query: 1940 LGEGVQEIDVSKLFK-------EPSGADIALLKLSSP----AVITDQVIPACLPTPNYVV 2086
+ Q + K PS D+ L++L A+ + V P CLP P+
Sbjct: 472 TTDVTQTFGIEKYIPYPMYSVFNPSDHDLVLIRLKKKGDRCAIRSQFVQPICLPEPSSPF 531
Query: 2087 ADRTACYITGWG---ETKGTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLA 2257
C I GWG E Y + L +EA +P++ + C+ E +S LCAG+
Sbjct: 532 PAGHKCQIAGWGHQDENVSGYSSSL-REALVPLVADHKCSSPEVYGADISPNMLCAGYFD 590
Query: 2258 GGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEE 2422
D+CQGDSGGPL C + L G+ SWG GC NKPGVY RV+++V WI++
Sbjct: 591 CKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLNKPGVYTRVAKYVDWIKD 645
Score = 70.5 bits (171), Expect = 8e-12
Identities = 35/103 (33%), Positives = 50/103 (48%), Gaps = 10/103 (9%)
Frame = +2
Query: 794 CTTPPPTSG------PTYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFP 955
C+ PP +G P+ +C G G YRG S ASG +C W++ ++
Sbjct: 268 CSCPPGHAGRLCNIVPSQRCFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGA 327
Query: 956 CKNL---EENYCRNPDGETAPWCYTT-DSEVRWDYCKIPSCGS 1072
L YCRNPD + PWCY DS + W+YC++ +C S
Sbjct: 328 AALLGLGPHAYCRNPDKDERPWCYVVKDSALSWEYCRLAACES 370
Score = 58.2 bits (139), Expect = 4e-08
Identities = 33/84 (39%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Frame = +2
Query: 317 CKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKY--SPEKFPLAGLEEN-YCRNPDNDE 487
C GNG YRG S SG+ C W+ + + S L GL + YCRNPD DE
Sbjct: 287 CFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDKDE 346
Query: 488 KGPWCYTT-DPETRFDYCDIPECE 556
+ PWCY D ++YC + CE
Sbjct: 347 R-PWCYVVKDSALSWEYCRLAACE 369
Score = 54.3 bits (129), Expect = 6e-07
Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
Frame = +2
Query: 563 CMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMN---YCRNPDGEP 733
C +G Y G S SG+ C +W S + ++ S L + YCRNPD +
Sbjct: 287 CFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDKDE 346
Query: 734 RPWCFTT-DPNKRWEFCDIPRC 796
RPWC+ D WE+C + C
Sbjct: 347 RPWCYVVKDSALSWEYCRLAAC 368
>ref|NP_001026985.1| HGF activator [Canis familiaris]
Length = 654
Score = 190 bits (483), Expect = 5e-48
Identities = 173/611 (28%), Positives = 245/611 (40%), Gaps = 72/611 (11%)
Frame = +2
Query: 806 PPTSGPTYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCK------NL 967
P TS P Q +GRG +T S+ SP T + PC+
Sbjct: 66 PATSAPEAQGPRGRG--------LTPPPRAAP--SSSSPGDPVLTVDGQPCRFPFRYGGR 115
Query: 968 EENYCRNPDGETAPWCYTT---DSEVRWDYCKIPSCGSSTTSTEHLDAPVPPEQTPVAQD 1138
+ C + WC TT D + W YC + APV E P A D
Sbjct: 116 MLHACTSEGSAHRKWCATTHNYDRDRAWGYC--------------VQAPVSREG-PAALD 160
Query: 1139 ------CYRGNG-------ESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTM 1279
C G SY T TGR C + R+E A ++
Sbjct: 161 SCASSPCLNGGSCSHTQDPGSYHCTCPMAFTGRNCDTEKCFDETRYEHLEAGDRWARVSQ 220
Query: 1280 NYCRNPD-ADKSPWCYTT-------DPRVRWEYCNLKKCSETEQQVTNFPAIAQVPSVED 1435
+ A C T P + C+L + T ++ ++
Sbjct: 221 GQVEQCECAGGQIRCEGTRHTACLSSPCLNGGTCHLIVATGTTVCSCPPGHAGRLCNIVP 280
Query: 1436 LSEDCMFGNGKRYRGKRATTVAGVPCQEWAA----QEPHRHSIFTPETNPRAGLEKN-YC 1600
S+ C GNG YRG +T +G+ C W + QE H S+ GL + YC
Sbjct: 281 -SQRCFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAAL---LGLGPHAYC 336
Query: 1601 RNPDGDDNGPWCYTTNPQKL-FDYCDIPQC--------VTSSF-------------DCGK 1714
RNPD D+ PWCY L ++YC + C +T++ CGK
Sbjct: 337 RNPDKDER-PWCYVVKDSALSWEYCRLAACESLARIPSLTTAVLLSQAEPAPVGRQTCGK 395
Query: 1715 PKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGH-FCGGTLISPEWVLTAKHCLEKSS 1891
+ R++GG S+P S PW ++ Y G FC G+L+ WV++A HC S
Sbjct: 396 RHKKRTFLRPRIIGGSSSLPGSHPWLAAI---YIGDSFCAGSLVHTCWVVSAAHCFSNSP 452
Query: 1892 SPSSYKVILGAHEEHHLGEGVQEIDVSKLFK-------EPSGADIALLKLSSP----AVI 2038
S V+LG H + + Q + K PS D+ L++L A+
Sbjct: 453 RRESVLVVLGQHFFNQTTDVTQTFGIEKYIPYPMYSVFNPSDHDLVLIRLKKKGDRCAIR 512
Query: 2039 TDQVIPACLPTPNYVVADRTACYITGWG---ETKGTYGAGLLKEARLPVIENKVCNRYEY 2209
+ V P CLP P+ C I GWG E Y + L +EA +P++ + C+ E
Sbjct: 513 SQFVQPICLPEPSSPFPAGHKCQIAGWGHQDENVSGYSSSL-REALVPLVADHKCSSPEV 571
Query: 2210 LDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYV 2389
+S LCAG+ D+CQGDSGGPL C + L G+ SWG GC NKPGVY
Sbjct: 572 YGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLNKPGVYT 631
Query: 2390 RVSRFVTWIEE 2422
RV+++V WI++
Sbjct: 632 RVAKYVDWIKD 642
Score = 70.5 bits (171), Expect = 8e-12
Identities = 35/103 (33%), Positives = 50/103 (48%), Gaps = 10/103 (9%)
Frame = +2
Query: 794 CTTPPPTSG------PTYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFP 955
C+ PP +G P+ +C G G YRG S ASG +C W++ ++
Sbjct: 265 CSCPPGHAGRLCNIVPSQRCFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGA 324
Query: 956 CKNL---EENYCRNPDGETAPWCYTT-DSEVRWDYCKIPSCGS 1072
L YCRNPD + PWCY DS + W+YC++ +C S
Sbjct: 325 AALLGLGPHAYCRNPDKDERPWCYVVKDSALSWEYCRLAACES 367
Score = 58.2 bits (139), Expect = 4e-08
Identities = 33/84 (39%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Frame = +2
Query: 317 CKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKY--SPEKFPLAGLEEN-YCRNPDNDE 487
C GNG YRG S SG+ C W+ + + S L GL + YCRNPD DE
Sbjct: 284 CFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDKDE 343
Query: 488 KGPWCYTT-DPETRFDYCDIPECE 556
+ PWCY D ++YC + CE
Sbjct: 344 R-PWCYVVKDSALSWEYCRLAACE 366
Score = 54.3 bits (129), Expect = 6e-07
Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
Frame = +2
Query: 563 CMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMN---YCRNPDGEP 733
C +G Y G S SG+ C +W S + ++ S L + YCRNPD +
Sbjct: 284 CFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDKDE 343
Query: 734 RPWCFTT-DPNKRWEFCDIPRC 796
RPWC+ D WE+C + C
Sbjct: 344 RPWCYVVKDSALSWEYCRLAAC 365
>ref|XP_850538.1| PREDICTED: hepatocyte growth factor activator isoform 1 [Canis
familiaris]
Length = 654
Score = 190 bits (482), Expect = 7e-48
Identities = 171/606 (28%), Positives = 243/606 (40%), Gaps = 67/606 (11%)
Frame = +2
Query: 806 PPTSGPTYQCLKGRGENY--RGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENY 979
P TS P Q +GRG R S+++ G Q R P + + L
Sbjct: 66 PATSAPEAQGPRGRGLTPPPRAAPSISSPGDPVLTVDGQPC----RFPFRYGGRMLHA-- 119
Query: 980 CRNPDGETAPWCYTT---DSEVRWDYCKIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRG 1150
C + WC TT D + W YC + APV E C
Sbjct: 120 CTSEGSAHRKWCATTHNYDRDRAWGYC--------------VQAPVSREGQAALDSCASS 165
Query: 1151 ---NGES---------YRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRN 1294
NG S Y T TGR C + R+E A ++
Sbjct: 166 PCLNGGSCSHTQDPGSYHCTCPMAFTGRNCDTEKCFDETRYEHLEAGDRWARVSQGQVEQ 225
Query: 1295 PD-ADKSPWCYTT-------DPRVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSEDC 1450
+ A C T P + C+L + T ++ ++ S+ C
Sbjct: 226 CECAGGQIRCEGTRHTACLSSPCLNGGTCHLIVATGTTVCSCPPGHAGRLCNIVP-SQRC 284
Query: 1451 MFGNGKRYRGKRATTVAGVPCQEWAA----QEPHRHSIFTPETNPRAGLEKN-YCRNPDG 1615
GNG YRG +T +G+ C W + QE H S+ GL + YCRNPD
Sbjct: 285 FVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAAL---LGLGPHAYCRNPDK 341
Query: 1616 DDNGPWCYTTNPQKL-FDYCDIPQC--------VTSSF-------------DCGKPKVEP 1729
D+ PWCY L ++YC + C +T++ CGK +
Sbjct: 342 DER-PWCYVVKDSALSWEYCRLAACESLARIPSLTTAVLLSQAEPAPVGRQTCGKRHKKR 400
Query: 1730 KKCPARVVGGCVSIPHSWPWQVSLRYRYRGH-FCGGTLISPEWVLTAKHCLEKSSSPSSY 1906
R++GG S+P S PW ++ Y G FC G+L+ WV++A HC S S
Sbjct: 401 TFLRPRIIGGSSSLPGSHPWLAAI---YIGDSFCAGSLVHTCWVVSAAHCFSNSPRRESV 457
Query: 1907 KVILGAHEEHHLGEGVQEIDVSKLFK-------EPSGADIALLKLSSP----AVITDQVI 2053
V+LG H + + Q + K PS D+ L++L A+ + V
Sbjct: 458 LVVLGQHFFNQTTDVTQTFGIEKYIPYPMYSVFNPSDHDLVLIRLKKKGDRCAIRSQFVQ 517
Query: 2054 PACLPTPNYVVADRTACYITGWG---ETKGTYGAGLLKEARLPVIENKVCNRYEYLDGKV 2224
P CLP P+ C I GWG E Y + L +EA +P++ + C+ E +
Sbjct: 518 PICLPEPSSPFPAGHKCQIAGWGHQDENVSGYSSSL-REALVPLVADHKCSSPEVYGADI 576
Query: 2225 SSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRF 2404
S LCAG+ D+CQGDSGGPL C + L G+ SWG GC NKPGVY RV+++
Sbjct: 577 SPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLNKPGVYTRVAKY 636
Query: 2405 VTWIEE 2422
V WI++
Sbjct: 637 VDWIKD 642
Score = 70.5 bits (171), Expect = 8e-12
Identities = 35/103 (33%), Positives = 50/103 (48%), Gaps = 10/103 (9%)
Frame = +2
Query: 794 CTTPPPTSG------PTYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFP 955
C+ PP +G P+ +C G G YRG S ASG +C W++ ++
Sbjct: 265 CSCPPGHAGRLCNIVPSQRCFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGA 324
Query: 956 CKNL---EENYCRNPDGETAPWCYTT-DSEVRWDYCKIPSCGS 1072
L YCRNPD + PWCY DS + W+YC++ +C S
Sbjct: 325 AALLGLGPHAYCRNPDKDERPWCYVVKDSALSWEYCRLAACES 367
Score = 58.2 bits (139), Expect = 4e-08
Identities = 33/84 (39%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Frame = +2
Query: 317 CKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKY--SPEKFPLAGLEEN-YCRNPDNDE 487
C GNG YRG S SG+ C W+ + + S L GL + YCRNPD DE
Sbjct: 284 CFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDKDE 343
Query: 488 KGPWCYTT-DPETRFDYCDIPECE 556
+ PWCY D ++YC + CE
Sbjct: 344 R-PWCYVVKDSALSWEYCRLAACE 366
Score = 54.3 bits (129), Expect = 6e-07
Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
Frame = +2
Query: 563 CMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMN---YCRNPDGEP 733
C +G Y G S SG+ C +W S + ++ S L + YCRNPD +
Sbjct: 284 CFVGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDKDE 343
Query: 734 RPWCFTT-DPNKRWEFCDIPRC 796
RPWC+ D WE+C + C
Sbjct: 344 RPWCYVVKDSALSWEYCRLAAC 365
Database: RefSeqCP
Posted date: Aug 1, 2006 9:25 PM
Number of letters in database: 19,266,565
Number of sequences in database: 33,732
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 125,422,453
Number of Sequences: 33732
Number of extensions: 3791930
Number of successful extensions: 14884
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 9483
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 14206
length of database: 19,266,565
effective HSP length: 112
effective length of database: 15,488,581
effective search space used: 12220490409
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqSP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= LVRM1_0045_D02
(2705 letters)
Database: RefSeqSP
1040 sequences; 434,620 total letters
Searching...done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_999219.1| T-plasminogen activator [Sus scrofa] 239 2e-64
Alignment gi|NP_999407.1| factor XII [Sus scrofa] 192 4e-50
Alignment gi|NP_999110.1| plasminogen activator [Sus scrofa] 188 5e-49
Alignment gi|NP_001001259.1| enteropeptidase, light chain (L chain) [Sus ... 182 3e-47
Alignment gi|NP_999356.1| tryptase [Sus scrofa] 181 6e-47
Alignment gi|NP_999239.1| kallikrein [Sus scrofa] 176 2e-45
Alignment gi|NP_999274.1| pancreatic elastase II [Sus scrofa] 176 3e-45
Alignment gi|NP_999198.1| preproacrosin [Sus scrofa] 166 3e-42
Alignment gi|NP_998959.1| tryptase [Sus scrofa] 162 4e-41
Alignment gi|NP_998988.1| pancreatic elastase I [Sus scrofa] 158 7e-40
>ref|NP_999219.1| T-plasminogen activator [Sus scrofa]
Length = 562
Score = 239 bits (611), Expect = 2e-64
Identities = 161/466 (34%), Positives = 227/466 (48%), Gaps = 35/466 (7%)
Frame = +2
Query: 1139 CYRGNGESYRGTSSTTITGRKCQSW----VSMTPHRHEKTPGNFPNA---GL-TMNYCRN 1294
CY G +YRGT STT +G +C +W ++ P+ G P+A GL NYCRN
Sbjct: 127 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYN-----GRRPDAVKLGLGNHNYCRN 181
Query: 1295 PDADKSPWCYTTDP-RVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSEDCMFGNGKR 1471
PD D PWCY + ++C+ C++ + E+C G G
Sbjct: 182 PDKDSKPWCYIFKAEKYSPDFCSTPACTKEK-------------------EECYTGKGLD 222
Query: 1472 YRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRA-GLEK-NYCRNPDGDDNGPWCYTT 1645
YRG R+ T++G C W + +N + GL K NYCRNPDGD PWC+
Sbjct: 223 YRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQ-PWCHVL 281
Query: 1646 NPQKL-FDYCDIPQCVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGH 1822
KL ++YCD+PQCVT CG + K+ R+ GG + S PWQ ++ + R
Sbjct: 282 KDHKLTWEYCDLPQCVT----CGLRQY--KEPQFRIKGGLYADITSHPWQAAIFVKNRRS 335
Query: 1823 -----FCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLF-- 1981
CGG LIS WVL+A HC ++ P +V+LG GE Q +V K
Sbjct: 336 PGERFLCGGILISSCWVLSAAHCFQERFPPHHVRVVLGRTYRLVPGEEEQAFEVEKYIVH 395
Query: 1982 ----KEPSGADIALLKLSSPAVI----TDQVIPACLPTPNYVVADRTACYITGWG--ETK 2131
+ DIALL+L S ++ +D V CLP N + D T C ++G+G E
Sbjct: 396 KEFDDDTYDNDIALLQLKSDSLTCAQESDAVRTVCLPEANLQLPDWTECELSGYGKHEAS 455
Query: 2132 GTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGG------IDSCQGDSGG 2293
+ + LKEA + + + C + +++ LCAG G D+CQGDSGG
Sbjct: 456 SPFYSERLKEAHVRLYPSSRCTSKHLFNKTITNNMLCAGDTRSGGDNANLHDACQGDSGG 515
Query: 2294 PLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIMR 2431
PLVC + + L GV SWGLGC + PGVY +V+ ++ WI + R
Sbjct: 516 PLVCMKGNHMTLVGVISWGLGCGQKDVPGVYTKVTNYLNWIRDNTR 561
Score = 119 bits (299), Expect = 3e-28
Identities = 69/173 (39%), Positives = 83/173 (47%), Gaps = 11/173 (6%)
Frame = +2
Query: 317 CKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYS---PEKFPLAGLEENYCRNPDNDE 487
C G YRGT S T+SG C W+ S Y+ P+ L NYCRNPD D
Sbjct: 127 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHNYCRNPDKDS 186
Query: 488 KGPWCYTTDPETRF-DYCDIPEC---EDECMHCSGEHYEGKISKTMSGIECQSWGSQSPH 655
K PWCY E D+C P C ++EC G Y G S TMSG C W S
Sbjct: 187 K-PWCYIFKAEKYSPDFCSTPACTKEKEECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLM 245
Query: 656 AHGYLPSKFPNKNL---KMNYCRNPDGEPRPWCFTTDPNK-RWEFCDIPRCTT 802
Y + L K NYCRNPDG+ +PWC +K WE+CD+P+C T
Sbjct: 246 GKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYCDLPQCVT 298
Score = 119 bits (298), Expect = 4e-28
Identities = 68/189 (35%), Positives = 90/189 (47%), Gaps = 9/189 (4%)
Frame = +2
Query: 833 CLKGRGENYRGTVSVTASGHTCQRWS----AQSPHKHNRTPENFPCKNLEENYCRNPDGE 1000
C + +G YRGT S T SG C W+ A P+ + R P+ NYCRNPD +
Sbjct: 127 CYEDQGITYRGTWSTTESGAECVNWNTSGLASMPY-NGRRPDAVKLGLGNHNYCRNPDKD 185
Query: 1001 TAPWCYTTDSE-VRWDYCKIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTS 1177
+ PWCY +E D+C P+C T ++CY G G YRGT
Sbjct: 186 SKPWCYIFKAEKYSPDFCSTPAC------------------TKEKEECYTGKGLDYRGTR 227
Query: 1178 STTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTM---NYCRNPDADKSPWCYT-TDPRVR 1345
S T++G C W S+ T N L + NYCRNPD D PWC+ D ++
Sbjct: 228 SLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLT 287
Query: 1346 WEYCNLKKC 1372
WEYC+L +C
Sbjct: 288 WEYCDLPQC 296
Score = 115 bits (289), Expect = 4e-27
Identities = 67/185 (36%), Positives = 89/185 (48%), Gaps = 8/185 (4%)
Frame = +2
Query: 536 CDIPECEDECMHCSGEHYEGKISKTMSGIECQSW---GSQSPHAHGYLPSKFPNKNLKMN 706
C+I + C G Y G S T SG EC +W G S +G P N
Sbjct: 119 CEI-DARATCYEDQGITYRGTWSTTESGAECVNWNTSGLASMPYNGRRPDAVKLGLGNHN 177
Query: 707 YCRNPDGEPRPWCFTTDPNKRW-EFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVTA 883
YCRNPD + +PWC+ K +FC P CT +C G+G +YRGT S+T
Sbjct: 178 YCRNPDKDSKPWCYIFKAEKYSPDFCSTPACTKEKE------ECYTGKGLDYRGTRSLTM 231
Query: 884 SGHTCQRWSAQSPHKHNRTPENFPCKNL---EENYCRNPDGETAPWCYT-TDSEVRWDYC 1051
SG C W++ T N + L + NYCRNPDG+T PWC+ D ++ W+YC
Sbjct: 232 SGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGDTQPWCHVLKDHKLTWEYC 291
Query: 1052 KIPSC 1066
+P C
Sbjct: 292 DLPQC 296
Score = 66.6 bits (161), Expect = 3e-12
Identities = 33/84 (39%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Frame = +2
Query: 314 ECKTGNGKNYRGTTSKTKSGVICQKWS---VSSPHIPKYSPEKFPLAGLEENYCRNPDND 484
EC TG G +YRGT S T SG C W+ + ++ L + NYCRNPD D
Sbjct: 214 ECYTGKGLDYRGTRSLTMSGAFCLPWNSLVLMGKIYTAWNSNAQTLGLGKHNYCRNPDGD 273
Query: 485 EKGPWCYT-TDPETRFDYCDIPEC 553
+ PWC+ D + ++YCD+P+C
Sbjct: 274 TQ-PWCHVLKDHKLTWEYCDLPQC 296
>ref|NP_999407.1| factor XII [Sus scrofa]
Length = 616
Score = 192 bits (487), Expect = 4e-50
Identities = 171/614 (27%), Positives = 247/614 (40%), Gaps = 50/614 (8%)
Frame = +2
Query: 731 PRPWCFTT---DPNKRWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGT-VSVTASGHT- 895
PRPWC TT + ++RW +C P C KG GT V++ H
Sbjct: 69 PRPWCATTPNFEKDQRWAYCLEPMKVKD--------HCNKGNPCQKGGTCVNMPNGPHCI 120
Query: 896 ---------CQRWSAQSPH-----KHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSE 1033
CQ+ P + N F + + C+ P + P
Sbjct: 121 CPDHFTGKHCQKEKCFEPQFLQFFQENEIWHRFEPAGVSKCQCKGPKAQCKP-------- 172
Query: 1034 VRWDYCKIPSC--GSSTTSTE-HLDAPVPPE------QTPVAQDCYRGNGESYRGTSSTT 1186
V C C G S TE H P + + CY G SYRG + TT
Sbjct: 173 VASQVCSTNPCLNGGSCLQTEGHRLCRCPTGYAGRLCDVDLKERCYSDRGLSYRGMAQTT 232
Query: 1187 ITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMN-YCRNPDADKSPWCYT-TDPRVRWEYCN 1360
++G CQ W S + T N GL + +CRNPD D PWC+ ++ W+YC
Sbjct: 233 LSGAPCQPWASEATY-WNMTAEQALNWGLGDHAFCRNPDNDTRPWCFVWRGDQLSWQYCR 291
Query: 1361 LKKCSETEQQVTNFPAIAQVPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPH 1540
L +C + Q PS S ++EP
Sbjct: 292 LARCQAPIGEAPPILTPTQSPSEHQDS-------------------------PLLSREPQ 326
Query: 1541 RHSIFTPET-NPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDIPQCVTSSFDCGKP 1717
P T P L +C P + GP +P CG+
Sbjct: 327 ------PTTQTPSQNLTSAWCAPP--EQRGP---------------LPS--AGLVGCGQR 361
Query: 1718 KVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLTAKHCLEKSSSP 1897
+ R+VGG V++P + P+ +L + +FC G+LI+P WVLTA HCL+ +P
Sbjct: 362 LRKRLSSLNRIVGGLVALPGAHPYIAALYWGQ--NFCAGSLIAPCWVLTAAHCLQNRPAP 419
Query: 1898 SSYKVILGAHEEHHLGEGVQEIDVSKLFKEPSGA------DIALLKLSSP-----AVITD 2044
V+LG + E Q + V S + D+AL++L A +
Sbjct: 420 EELTVVLGQDRHNQSCEQCQTLAVRSYRLHESYSPKTYQHDLALVRLKETADGCCAHPSP 479
Query: 2045 QVIPACLP--TPNYVVADRTACYITGWG---ETKGTYGAGLLKEARLPVIENKVCNRYEY 2209
V P CLP + + C + GWG E Y + L+EA++P+I + C+ +
Sbjct: 480 FVQPVCLPRSVASSAEPEGALCEVAGWGHQFEGAEEY-SSFLQEAQVPLISPERCSAADV 538
Query: 2210 LDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEKD---KYILQGVTSWGLGCALPNKPG 2380
+ LCAG L GG D+CQGDSGGPLVC ++ + +L+G+ SWG GC KPG
Sbjct: 539 HGAAFTPGMLCAGFLEGGTDACQGDSGGPLVCEDETAERQLVLRGIVSWGSGCGDRLKPG 598
Query: 2381 VYVRVSRFVTWIEE 2422
VY V+ ++ WI+E
Sbjct: 599 VYTDVANYLAWIQE 612
Score = 62.8 bits (151), Expect = 4e-11
Identities = 41/158 (25%), Positives = 64/158 (40%), Gaps = 5/158 (3%)
Frame = +2
Query: 536 CDIPECEDECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCR 715
CD+ + ++ C G Y G T+SG CQ W S++ + + +CR
Sbjct: 209 CDV-DLKERCYSDRGLSYRGMAQTTLSGAPCQPWASEATYWNMTAEQALNWGLGDHAFCR 267
Query: 716 NPDGEPRPWCFTTDPNK-RWEFCDIPRCTTP----PPTSGPTYQCLKGRGENYRGTVSVT 880
NPD + RPWCF ++ W++C + RC P PP PT +
Sbjct: 268 NPDNDTRPWCFVWRGDQLSWQYCRLARCQAPIGEAPPILTPTQ----------------S 311
Query: 881 ASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPD 994
S H ++ P +TP +NL +C P+
Sbjct: 312 PSEHQDSPLLSREPQPTTQTPS----QNLTSAWCAPPE 345
Score = 53.1 bits (126), Expect = 3e-08
Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 1/102 (0%)
Frame = +2
Query: 254 TSPIARMRDVVLFEKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEK 433
T R+ DV L E+ C + G +YRG T SG CQ W+ + + + +
Sbjct: 202 TGYAGRLCDVDLKER------CYSDRGLSYRGMAQTTLSGAPCQPWASEATYWNMTAEQA 255
Query: 434 FPLAGLEENYCRNPDNDEKGPWCYT-TDPETRFDYCDIPECE 556
+ +CRNPDND + PWC+ + + YC + C+
Sbjct: 256 LNWGLGDHAFCRNPDNDTR-PWCFVWRGDQLSWQYCRLARCQ 296
>ref|NP_999110.1| plasminogen activator [Sus scrofa]
Length = 442
Score = 188 bits (478), Expect = 5e-49
Identities = 125/368 (33%), Positives = 173/368 (47%), Gaps = 40/368 (10%)
Frame = +2
Query: 1433 DLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNP-RAGLEK-NYCRN 1606
D S+ C GNG YRGK T G PC W + ++ + + GL K NYCRN
Sbjct: 67 DTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRN 126
Query: 1607 PDGDDNGPWCYT-TNPQKLFDYCDIPQCVTSS-------------------FDCGKPKVE 1726
PD + PWCY ++L C +P C F CG+ +
Sbjct: 127 PD-NQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQCGQKALR 185
Query: 1727 PKKCPARVVGGCVSIPHSWPWQVSLRYRYRG----HFCGGTLISPEWVLTAKHCLEKSSS 1894
P+ ++VGG + + PW ++ R+RG + CGG+LISP WV++A HC
Sbjct: 186 PR---FKIVGGKSTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINYQH 242
Query: 1895 PSSYKVILGAHEEHHLGEGVQEIDVSKLFKEPSGA--------DIALLKLSSP----AVI 2038
Y V LG H G + +V KL + DIALLK+ + A
Sbjct: 243 KEDYIVYLGRQTLHSSTHGEMKFEVEKLILHEDYSADSLAHHNDIALLKIRTDKGQCAQP 302
Query: 2039 TDQVIPACLPTPNYVVADRTACYITGWG-ETKGTY-GAGLLKEARLPVIENKVCNRYEYL 2212
+ + CLP N +C I G+G E Y LK + ++ ++ C + Y
Sbjct: 303 SRSIQTICLPPVNGDAHFGASCEIVGFGKEDPSDYLYPEQLKMTVVKLVSHRECQQPHYY 362
Query: 2213 DGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVR 2392
+V++K LCA DSCQGDSGGPLVC + + L G+ SWG CA+ +KPGVY R
Sbjct: 363 GSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSTQGRLTLTGIVSWGRECAMKDKPGVYTR 422
Query: 2393 VSRFVTWI 2416
VSRF+TWI
Sbjct: 423 VSRFLTWI 430
Score = 62.8 bits (151), Expect = 4e-11
Identities = 46/186 (24%), Positives = 70/186 (37%), Gaps = 15/186 (8%)
Frame = +2
Query: 776 FCDIPRCTTPPPTSGP------TYQCLKGRGENYRGTVSVTASGHTCQRWSAQSP---HK 928
F +I RC+ P G + C +G G +YRG + G C W++ +
Sbjct: 47 FSNIQRCSCPKKFQGEHCEIDTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTY 106
Query: 929 HNRTPENFPCKNLEENYCRNPDGETAPWCYT-TDSEVRWDYCKIPSCGSSTTSTEHLDAP 1105
H P+ + NYCRNPD + PWCY + C +P+C + D
Sbjct: 107 HAHRPDALQLGLGKHNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGK 166
Query: 1106 VP---PEQT--PVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAG 1270
P PE+ Q R + G S+T + Q W + RH + G
Sbjct: 167 NPFSTPEKVEFQCGQKALRPRFKIVGGKSTTI----ENQPWFAAIYRRHRGGSVTYVCGG 222
Query: 1271 LTMNYC 1288
++ C
Sbjct: 223 SLISPC 228
Score = 61.6 bits (148), Expect = 9e-11
Identities = 44/147 (29%), Positives = 58/147 (39%), Gaps = 8/147 (5%)
Frame = +2
Query: 1130 AQDCYRGNGESYRGTSSTTITGRKCQSWVSMT---PHRHEKTPGNFPNAGLTMNYCRNPD 1300
+Q C+ GNG SYRG ++T GR C W S T H P NYCRNPD
Sbjct: 69 SQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPD 128
Query: 1301 ADKSPWCYT-TDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSEDCMFGNGKRYR 1477
+ PWCY + + C + CS E + + E + C G++
Sbjct: 129 NQRRPWCYVQVGLKQLVQECMVPNCSGGESHRPAYDGKNPFSTPEKVEFQC----GQKAL 184
Query: 1478 GKRATTVAG----VPCQEWAAQEPHRH 1546
R V G + Q W A RH
Sbjct: 185 RPRFKIVGGKSTTIENQPWFAAIYRRH 211
Score = 55.1 bits (131), Expect = 8e-09
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Frame = +2
Query: 530 DYCDIPECEDECMHCSGEHYEGKISKTMSGIECQSWGSQSPHA---HGYLPSKFPNKNLK 700
++C+I + C +G Y GK + G C W S + H + P K
Sbjct: 62 EHCEI-DTSQTCFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGK 120
Query: 701 MNYCRNPDGEPRPWCFTTDPNKRW-EFCDIPRCT 799
NYCRNPD + RPWC+ K+ + C +P C+
Sbjct: 121 HNYCRNPDNQRRPWCYVQVGLKQLVQECMVPNCS 154
Score = 54.7 bits (130), Expect = 1e-08
Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
Frame = +2
Query: 317 CKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYS---PEKFPLAGLEENYCRNPDNDE 487
C GNG +YRG + G C W+ ++ + Y P+ L + NYCRNPDN +
Sbjct: 72 CFEGNGHSYRGKANTNTGGRPCLPWNSATVLLNTYHAHRPDALQLGLGKHNYCRNPDN-Q 130
Query: 488 KGPWCYT-TDPETRFDYCDIPECEDECMHCSGEHYEGK 598
+ PWCY + C +P C H Y+GK
Sbjct: 131 RRPWCYVQVGLKQLVQECMVPNCSGGESHRPA--YDGK 166
>ref|NP_001001259.1| enteropeptidase, light chain (L chain) [Sus scrofa]
Length = 1034
Score = 182 bits (463), Expect = 3e-47
Identities = 105/279 (37%), Positives = 160/279 (57%), Gaps = 10/279 (3%)
Frame = +2
Query: 1622 NGPWCYTTNPQKLFDYCDIPQCVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSL 1801
NG T + Q D + QC S CGK +V + P ++VGG S +WPW V+L
Sbjct: 761 NGSLILTASEQCFEDSLILLQCNHKS--CGKKQVAQEVSP-KIVGGNDSREGAWPWVVAL 817
Query: 1802 RYRYRGHFCGGTLISPEWVLTAKHCLE-KSSSPSSYKVILGAHEEHHLGEG------VQE 1960
Y + CG +L+S +W+++A HC+ ++ PS +K ILG H +L + E
Sbjct: 818 YYNGQ-LLCGASLVSRDWLVSAAHCVYGRNLEPSKWKAILGLHMTSNLTSPQIVTRLIDE 876
Query: 1961 IDVSKLF-KEPSGADIALLKLSSPAVITDQVIPACLPTPNYVVADRTACYITGWGET--K 2131
I ++ + + +DIA++ L TD + P CLP N V C I GWG+ +
Sbjct: 877 IVINPHYNRRRKDSDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRICSIAGWGKVIYQ 936
Query: 2132 GTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFE 2311
G+ A +L+EA +P++ N+ C + + + ++ +CAG+ GGIDSCQGDSGGPL+C E
Sbjct: 937 GS-PADILQEADVPLLSNEKCQQ-QMPEYNITENMMCAGYEEGGIDSCQGDSGGPLMCLE 994
Query: 2312 KDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIM 2428
++++L GVTS+G CALPN+PGVY RV +F WI+ +
Sbjct: 995 NNRWLLAGVTSFGYQCALPNRPGVYARVPKFTEWIQSFL 1033
>ref|NP_999356.1| tryptase [Sus scrofa]
Length = 275
Score = 181 bits (460), Expect = 6e-47
Identities = 104/250 (41%), Positives = 141/250 (56%), Gaps = 19/250 (7%)
Frame = +2
Query: 1742 ARVVGGCVSIPHSWPWQVSLRY--RYRGHFCGGTLISPEWVLTAKHCL-EKSSSPSSYKV 1912
A +VGG + H WPWQVSLR +Y HFCGG+LI P+WVLTA HC + + P +V
Sbjct: 29 AGIVGGKEAPGHKWPWQVSLRCLDQYWKHFCGGSLIHPQWVLTAAHCFGPEKADPLYIRV 88
Query: 1913 ILGAHEEHHLGEGVQEIDVSKLFKEPS------GADIALLKLSSPAVITDQVIPACLPTP 2074
LG E HL + + VS++ P+ GADIALL+L P ++ V P LP
Sbjct: 89 QLG---EQHLYYQDRLLLVSRIIVHPNYYDEVNGADIALLELEDPVNLSSHVQPVTLPPA 145
Query: 2075 NYVVADRTACYITGWGETKGTYGAGL---LKEARLPVIENKVCNRYEYLDGK-------V 2224
+ T C++TGWG+ + LK+ R+P++EN C+ +L V
Sbjct: 146 SETFPKGTRCWVTGWGDVHSGWPLPPPYPLKQVRVPIVENSECDMQYHLGLSTGDNIPIV 205
Query: 2225 SSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRF 2404
LCAG + G DSCQGDSGGPLVC ++ GV SWG GCALPN+PG+Y RV+ +
Sbjct: 206 RDDMLCAG--SEGHDSCQGDSGGPLVCRVNGTWLQAGVVSWGEGCALPNRPGIYTRVTHY 263
Query: 2405 VTWIEEIMRR 2434
+ WI + + R
Sbjct: 264 LDWIHQCIPR 273
>ref|NP_999239.1| kallikrein [Sus scrofa]
Length = 643
Score = 176 bits (447), Expect = 2e-45
Identities = 98/240 (40%), Positives = 139/240 (57%), Gaps = 10/240 (4%)
Frame = +2
Query: 1733 KCPARVVGGCVSIPHSWPWQVSLRYRYRG--HFCGGTLISPEWVLTAKHCLEKSSSPSSY 1906
K R+VGG S WPWQVSL+ + R H CGG++I +WVLTA HC + S P +
Sbjct: 394 KANTRIVGGTDSFLGEWPWQVSLQAKLRAQNHLCGGSIIGHQWVLTAAHCFDGLSLPDIW 453
Query: 1907 KVILGAHEEHHLGEG-----VQEIDVSKLFKE-PSGADIALLKLSSPAVITDQVIPACLP 2068
++ G + + V+EI + + +K SG DIALLKL +P TD P CLP
Sbjct: 454 RIYGGILNISEITKETPFSQVKEIIIHQNYKILESGHDIALLKLETPLNYTDFQKPICLP 513
Query: 2069 TPNYVVADRTACYITGWG--ETKGTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELC 2242
+ + T C++TGWG E KG +L++ +P++ N+ C + Y D K+S + +C
Sbjct: 514 SRDDTNVVYTNCWVTGWGFTEEKGEI-QNILQKVNIPLVSNEECQK-SYRDHKISKQMIC 571
Query: 2243 AGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEE 2422
AG+ GG D+C+G+SGGPLVC + L G TSWG GCA +PGVY +V ++ WI E
Sbjct: 572 AGYKEGGKDACKGESGGPLVCKYNGIWHLVGTTSWGEGCARREQPGVYTKVIEYMDWILE 631
>ref|NP_999274.1| pancreatic elastase II [Sus scrofa]
Length = 269
Score = 176 bits (445), Expect = 3e-45
Identities = 105/266 (39%), Positives = 148/266 (55%), Gaps = 16/266 (6%)
Frame = +2
Query: 1688 VTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRG---HFCGGTLISPEWV 1858
V + CG P P+ RVVGG + P+SWPWQVSL+Y G H CGGTL+ WV
Sbjct: 11 VAGALSCGLPANLPQL--PRVVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWV 68
Query: 1859 LTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLFKEP--------SGADIALL 2014
LTA HC+ SS +Y+V+LG H G + VSKL +G DIALL
Sbjct: 69 LTAAHCI---SSSRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALL 125
Query: 2015 KLSSPAVITDQVIPACLPTPNYVVADRTACYITGWGETKGTYGAG--LLKEARLPVIENK 2188
KL+SP +TD++ CLP ++ + CY+TGWG + T GA +L++ +L V++
Sbjct: 126 KLASPVSLTDKIQLGCLPAAGTILPNNYVCYVTGWGRLQ-TNGASPDILQQGQLLVVDYA 184
Query: 2189 VCNRYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVC-FEKDKYILQGVTSWG--LGC 2359
C++ + V + +CAG G I SC GDSGGPL C ++ + G+ S+G LGC
Sbjct: 185 TCSKPGWWGSTVKTNMICAGG-DGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGC 243
Query: 2360 ALPNKPGVYVRVSRFVTWIEEIMRRN 2437
+KP V+ RVS ++ WI ++ N
Sbjct: 244 NYYHKPSVFTRVSNYIDWINSVIANN 269
>ref|NP_999198.1| preproacrosin [Sus scrofa]
Length = 400
Score = 166 bits (420), Expect = 3e-42
Identities = 97/259 (37%), Positives = 150/259 (57%), Gaps = 22/259 (8%)
Frame = +2
Query: 1706 CGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLR-YRY----RGHFCGGTLISPEWVLTAK 1870
CG + + RVVGG + P +WPW VSL+ + Y R H CGG L++ WVLTA
Sbjct: 25 CGLRFRQKLESGMRVVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAA 84
Query: 1871 HCLEKSSSPSSYKVILGAHE-----EHHLGEGVQEIDVSKLF---KEPSGA---DIALLK 2017
HC + + +++I GA+E + +QE V ++ K SG DIAL+K
Sbjct: 85 HCFKNKKKVTDWRLIFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIK 144
Query: 2018 LSSPAVITDQVIPACLPT--PNYVVADRTACYITGWG--ETKGTYGAGLLKEARLPVIEN 2185
++ P + P CLP A +T C++TGWG + KG + L+EAR+ +I+
Sbjct: 145 ITPPVPCGPFIGPGCLPQFKAGPPRAPQT-CWVTGWGYLKEKGPRTSPTLQEARVALIDL 203
Query: 2186 KVCNRYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEK--DKYILQGVTSWGLGC 2359
++CN ++ +G+V+S +CAG+ G ID+CQGDSGGPL+C ++ + +++ G+TSWG+GC
Sbjct: 204 ELCNSTQWYNGRVTSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGC 263
Query: 2360 ALPNKPGVYVRVSRFVTWI 2416
A +PGVY ++ WI
Sbjct: 264 ARAKRPGVYTSTWPYLNWI 282
>ref|NP_998959.1| tryptase [Sus scrofa]
Length = 277
Score = 162 bits (410), Expect = 4e-41
Identities = 100/267 (37%), Positives = 144/267 (53%), Gaps = 24/267 (8%)
Frame = +2
Query: 1709 GKPKVEPKKCPAR----VVGGCVSIPHSWPWQVSLR-YRYR----GHFCGGTLISPEWVL 1861
G V P + P +VGG +PWQVSLR YR + H CGG+L+ P+WVL
Sbjct: 14 GSVPVTPGRGPRHELVGIVGGHDVSTWKYPWQVSLRSYRVKLGRWMHHCGGSLVHPQWVL 73
Query: 1862 TAKHCLEKSS-SPSSYKVILGAHEEHHLGEGVQEIDVSKLFKEPS-------GADIALLK 2017
TA HC++ + P +V +G + L +G Q V ++ + P GADIALL+
Sbjct: 74 TAAHCVDSHNLKPQDVRVQVG---QLKLYDGDQLTKVKQIIRHPKYLGFAKGGADIALLQ 130
Query: 2018 LSSPAVITDQVIPACLPTPNYVVADRTACYITGWGETKGTYGAGL---LKEARLPVIENK 2188
L +P ++ +V P+ V C +TGWG K L+E +P++ NK
Sbjct: 131 LEAPLTLSARVNVVGTPSATLKVPKGKRCSVTGWGNIKHNLSLPPPYHLQEVEVPIVANK 190
Query: 2189 VCNRYEYLDGK----VSSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLG 2356
VCN++ Y G + + LCAG + G+DSCQGDSGGPL+C ++ G+ SWG G
Sbjct: 191 VCNKH-YRTGPNSKPIKADMLCAG--SKGLDSCQGDSGGPLMCSWNGTWVQVGIVSWGRG 247
Query: 2357 CALPNKPGVYVRVSRFVTWIEEIMRRN 2437
C L N PGVY+RV +V+WI + + R+
Sbjct: 248 CGLHNFPGVYIRVMSYVSWIYQYVPRS 274
>ref|NP_998988.1| pancreatic elastase I [Sus scrofa]
Length = 266
Score = 158 bits (399), Expect = 7e-40
Identities = 94/248 (37%), Positives = 137/248 (55%), Gaps = 16/248 (6%)
Frame = +2
Query: 1742 ARVVGGCVSIPHSWPWQVSLRYRYRG---HFCGGTLISPEWVLTAKHCLEKSSSPSSYKV 1912
ARVVGG + +SWP Q+SL+YR H CGGTLI WV+TA HC+++ + ++V
Sbjct: 25 ARVVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELT---FRV 81
Query: 1913 ILGAHEEHHLGEGVQEIDVSKLFKEP--------SGADIALLKLSSPAVITDQVIPACLP 2068
++G H + Q + V K+ P +G DIALL+L + V LP
Sbjct: 82 VVGEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLGQSVTLNSYVQLGVLP 141
Query: 2069 TPNYVVADRTACYITGWGETKGTYG--AGLLKEARLPVIENKVCNRYEYLDGKVSSKELC 2242
++A+ + CYITGWG T+ T G A L++A LP ++ + + Y V + +C
Sbjct: 142 RAGTILANNSPCYITGWGLTR-TNGQLAQTLQQAYLPTVDYAILSSSSYWGSTVKNSMVC 200
Query: 2243 AGHLAGGIDS-CQGDSGGPLVCFEKDKYILQGVTSW--GLGCALPNKPGVYVRVSRFVTW 2413
AG G+ S CQGDSGGPL C +Y + GVTS+ LGC + KP V+ RVS +++W
Sbjct: 201 AG--GDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISW 258
Query: 2414 IEEIMRRN 2437
I ++ N
Sbjct: 259 INNVIASN 266
Database: RefSeqSP
Posted date: Aug 1, 2006 7:14 PM
Number of letters in database: 434,620
Number of sequences in database: 1040
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,881,797
Number of Sequences: 1040
Number of extensions: 85408
Number of successful extensions: 419
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 232
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 327
length of database: 434,620
effective HSP length: 85
effective length of database: 346,220
effective search space used: 282515520
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqHP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= LVRM1_0045_D02
(2705 letters)
Database: RefSeqHP
39,411 sequences; 17,774,539 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_000292.1| plasminogen [Homo sapiens] 1416 0.0
Alignment gi|NP_005568.1| lipoprotein, Lp(a) [Homo sapiens] 988 0.0
Alignment gi|XP_946885.1| PREDICTED: similar to Apolipoprotein(a) precurs... 613 e-175
Alignment gi|XP_931416.1| PREDICTED: similar to Apolipoprotein(a) precurs... 613 e-175
Alignment gi|NP_000592.3| hepatocyte growth factor isoform 1 preproprotei... 507 e-143
Alignment gi|NP_001010932.1| hepatocyte growth factor isoform 3 precursor... 496 e-140
Alignment gi|NP_066278.2| macrophage stimulating 1 (hepatocyte growth fac... 492 e-139
Alignment gi|NP_127509.1| plasminogen activator, tissue type isoform 3 pr... 243 6e-64
Alignment gi|NP_000921.1| plasminogen activator, tissue type isoform 1 pr... 243 6e-64
Alignment gi|NP_001010931.1| hepatocyte growth factor isoform 2 precursor... 234 4e-61
>ref|NP_000292.1| plasminogen [Homo sapiens]
Length = 810
Score = 1416 bits (3665), Expect = 0.0
Identities = 637/810 (78%), Positives = 701/810 (86%), Gaps = 1/810 (0%)
Frame = +2
Query: 11 MDHKEVVXXXXXXXXXXXXXXXXXYVNTQGAFLFSLSRKQVAARSVEECAAKCEAETNFI 190
M+HKEVV YVNTQGA LFS+++KQ+ A S+EECAAKCE + F
Sbjct: 1 MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFT 60
Query: 191 CRAFQYHSKDQQCVVMAENSKTSPIARMRDVVLFEKRIYLSECKTGNGKNYRGTTSKTKS 370
CRAFQYHSK+QQCV+MAEN K+S I RMRDVVLFEK++YLSECKTGNGKNYRGT SKTK+
Sbjct: 61 CRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKN 120
Query: 371 GVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRNPDNDEKGPWCYTTDPETRFDYCDIPE 550
G+ CQKWS +SPH P++SP P GLEENYCRNPDND +GPWCYTTDPE R+DYCDI E
Sbjct: 121 GITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILE 180
Query: 551 CEDECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGE 730
CE+ECMHCSGE+Y+GKISKTMSG+ECQ+W SQSPHAHGY+PSKFPNKNLK NYCRNPD E
Sbjct: 181 CEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRE 240
Query: 731 PRPWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVTASGHTCQRWS 910
RPWCFTTDPNKRWE CDIPRCTTPPP+SGPTYQCLKG GENYRG V+VT SGHTCQ WS
Sbjct: 241 LRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWS 300
Query: 911 AQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVRWDYCKIPSCGSSTTSTE 1090
AQ+PH HNRTPENFPCKNL+ENYCRNPDG+ APWC+TT+S+VRW+YCKIPSC SS STE
Sbjct: 301 AQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTE 360
Query: 1091 HLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAG 1270
L PPE TPV QDCY G+G+SYRGTSSTT TG+KCQSW SMTPHRH+KTP N+PNAG
Sbjct: 361 QLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAG 420
Query: 1271 LTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLS-ED 1447
LTMNYCRNPDADK PWC+TTDP VRWEYCNLKKCS TE V P + +P VE S ED
Sbjct: 421 LTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEED 480
Query: 1448 CMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNG 1627
CMFGNGK YRGKRATTV G PCQ+WAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGD G
Sbjct: 481 CMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGG 540
Query: 1628 PWCYTTNPQKLFDYCDIPQCVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRY 1807
PWCYTTNP+KL+DYCD+PQC SFDCGKP+VEPKKCP RVVGGCV+ PHSWPWQVSLR
Sbjct: 541 PWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRT 600
Query: 1808 RYRGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLFKE 1987
R+ HFCGGTLISPEWVLTA HCLEKS PSSYKVILGAH+E +L VQEI+VS+LF E
Sbjct: 601 RFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLE 660
Query: 1988 PSGADIALLKLSSPAVITDQVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLKEAR 2167
P+ DIALLKLSSPAVITD+VIPACLP+PNYVVADRT C+ITGWGET+GT+GAGLLKEA+
Sbjct: 661 PTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQ 720
Query: 2168 LPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSW 2347
LPVIENKVCNRYE+L+G+V S ELCAGHLAGG DSCQGDSGGPLVCFEKDKYILQGVTSW
Sbjct: 721 LPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSW 780
Query: 2348 GLGCALPNKPGVYVRVSRFVTWIEEIMRRN 2437
GLGCA PNKPGVYVRVSRFVTWIE +MR N
Sbjct: 781 GLGCARPNKPGVYVRVSRFVTWIEGVMRNN 810
>ref|NP_005568.1| lipoprotein, Lp(a) [Homo sapiens]
Length = 4548
Score = 988 bits (2555), Expect = 0.0
Identities = 470/808 (58%), Positives = 551/808 (68%), Gaps = 70/808 (8%)
Frame = +2
Query: 224 QCVVMAENSKTSPIARMRDVVLFEKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSS 403
QC V E+S + + + E+ + +C G+G++YRG+ S T +G CQ WS +
Sbjct: 3752 QCPV-TESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMT 3810
Query: 404 PHIPKYSPEKFPLAGLEENYCRNPDNDEKGPWCYTTDPETRFDYCDIPECE--------- 556
PH + + E +P GL NYCRNPD + + PWCYT DP R++YC++ +C
Sbjct: 3811 PHWHQRTTEYYPNGGLTRNYCRNPDAEIR-PWCYTMDPSVRWEYCNLTQCPVMESTLLTT 3869
Query: 557 ------------------------DECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHG 664
+C G+ Y G +S T++G CQSW S +PH H
Sbjct: 3870 PTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHR 3929
Query: 665 YLPSKFPNKNLKMNYCRNPDGEPRPWCFTTDPNKRWEFCDIPRC--------TTP----- 805
+P +PN L NYCRNPD E RPWC+T DP+ RWE+C++ RC TTP
Sbjct: 3930 RIPLYYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPV 3989
Query: 806 ----------PPTSGPTYQ-CLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENF 952
PP P Q C G G +YRG S T +G TCQ WS+ PH H RTPEN+
Sbjct: 3990 PSTEAPSEQAPPEKSPVVQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENY 4049
Query: 953 PCKNLEENYCRNPDGETAPWCYTTDSEVRWDYCKIPSCGSSTT------------STEHL 1096
P L ENYCRNPD PWCYTTD VRW+YC + C + + S E
Sbjct: 4050 PNAGLTENYCRNPDSGKQPWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAH 4109
Query: 1097 DAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLT 1276
P EQTPV + CY GNG+SYRGT STT+TGR CQSW SMTPHRH++TP N+PN GLT
Sbjct: 4110 SEAAPTEQTPVVRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLT 4169
Query: 1277 MNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-DCM 1453
MNYCRNPDAD PWC+T DP +RWEYCNL +CS+TE V P + QVPS+ SE DCM
Sbjct: 4170 MNYCRNPDADTGPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCM 4229
Query: 1454 FGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPW 1633
FGNGK YRGK+ATTV G PCQEWAAQEPHRHS F P TN AGLEKNYCRNPDGD NGPW
Sbjct: 4230 FGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPW 4289
Query: 1634 CYTTNPQKLFDYCDIPQCVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRY 1813
CYT NP+KLFDYCDIP C +SSFDCGKP+VEPKKCP +VGGCV+ PHSWPWQVSLR R+
Sbjct: 4290 CYTMNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRF 4349
Query: 1814 RGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLFKEPS 1993
HFCGGTLISPEWVLTA HCL+KSS PSSYKVILGAH+E +L VQEI+VS+LF EP+
Sbjct: 4350 GKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPT 4409
Query: 1994 GADIALLKLSSPAVITDQVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLKEARLP 2173
ADIALLKLS PAVITD+V+PACLP+P+Y+V RT CYITGWGET+GT+G GLLKEA+L
Sbjct: 4410 QADIALLKLSRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLL 4469
Query: 2174 VIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGL 2353
VIEN+VCN Y+Y +CA HLA G DSCQGDSGGPLVCFEKDKYILQGVTSWGL
Sbjct: 4470 VIENEVCNHYKY---------ICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL 4520
Query: 2354 GCALPNKPGVYVRVSRFVTWIEEIMRRN 2437
GCA PNKPGVY RVSRFVTWIE +MR N
Sbjct: 4521 GCARPNKPGVYARVSRFVTWIEGMMRNN 4548
Score = 503 bits (1296), Expect = e-142
Identities = 246/539 (45%), Positives = 301/539 (55%), Gaps = 72/539 (13%)
Frame = +2
Query: 287 LFEKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYC 466
L E+ + +C G++YRGT S T +G CQ WS +PH +PE +P AGL NYC
Sbjct: 3552 LTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYC 3611
Query: 467 RNPDNDEKGPWCYTTDPETRFDYCDIPEC------------------------------- 553
RNPD + + PWCYT DP R++YC++ +C
Sbjct: 3612 RNPDAEIR-PWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQS 3670
Query: 554 --EDECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDG 727
+C H G+ Y G S T++G CQSW S +PH H +PN L NYCRNPD
Sbjct: 3671 PGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA 3730
Query: 728 EPRPWCFTTDPNKRWEFCDIPRCTT---------------PPPTSGPTYQ-CLKGRGENY 859
E PWC+T DPN RWE+C++ +C P PT Q C G G++Y
Sbjct: 3731 EISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSY 3790
Query: 860 RGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVR 1039
RG+ S T +G TCQ WS+ +PH H RT E +P L NYCRNPD E PWCYT D VR
Sbjct: 3791 RGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMDPSVR 3850
Query: 1040 WDYCKIPSCG--SSTTSTEHLDAPVPPEQTPV----------AQDCYRGNGESYRGTSST 1183
W+YC + C ST T PVP + P QDCYRG+G+SYRGT ST
Sbjct: 3851 WEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRGTLST 3910
Query: 1184 TITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNL 1363
TITGR CQSW SMTPH H + P +PNAGLT NYCRNPDA+ PWCYT DP VRWEYCNL
Sbjct: 3911 TITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNL 3970
Query: 1364 KKCSETEQQVTNFPAIAQVPSVEDLSE-----------DCMFGNGKRYRGKRATTVAGVP 1510
+C TE V P +A VPS E SE DC G+G+ YRG +TTV G
Sbjct: 3971 TRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYHGDGRSYRGISSTTVTGRT 4030
Query: 1511 CQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDIPQC 1687
CQ W++ PH H TPE P AGL +NYCRNPD PWCYTT+P ++YC++ QC
Sbjct: 4031 CQSWSSMIPHWHQ-RTPENYPNAGLTENYCRNPDSGKQ-PWCYTTDPCVRWEYCNLTQC 4087
Score = 499 bits (1286), Expect = e-141
Identities = 246/545 (45%), Positives = 311/545 (57%), Gaps = 80/545 (14%)
Frame = +2
Query: 293 EKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRN 472
E+R + EC GNG++YRGT S T +G CQ WS +PH +PE +P AGL NYCRN
Sbjct: 2870 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 2929
Query: 473 PDNDEKGPWCYTTDPETRFDYCDIPECED------------------------------- 559
PD P+CYT DP R++YC++ +C D
Sbjct: 2930 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 2988
Query: 560 --ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEP 733
EC H +G+ Y G S T++G CQ+W S +PH+H P +PN L MNYCRNPD
Sbjct: 2989 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 3048
Query: 734 RPWCFTTDPNKRWEFCDIPRCT------------TPPPT------SGPTYQ------CLK 841
P+C+T DP RWE+C++ +C+ TP P+ PT Q C
Sbjct: 3049 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 3108
Query: 842 GRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYT 1021
G G++YRGT S T +G TCQ WS+ +PH H+RTPE +P L NYCRNPD AP+CYT
Sbjct: 3109 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 3168
Query: 1022 TDSEVRWDYCKIPSCGSS---------TTSTEHLDAP---VPPEQTPVAQDCYRGNGESY 1165
D VRW+YC + C + T L+AP P EQ P Q+CY GNG+SY
Sbjct: 3169 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 3228
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVR 1345
RGT STT+TGR CQ+W SMTPH H +TP +PNAGL MNYCRNPDA +P+CYT DP VR
Sbjct: 3229 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 3288
Query: 1346 WEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-----------DCMFGNGKRYRGKRAT 1492
WEYCNL +CS+ E P + VPS+E SE +C GNG+ YRG +T
Sbjct: 3289 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 3348
Query: 1493 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 1672
TV G CQ W++ PH HS TPE P AGL NYCRNPD P+CYT +P ++YC
Sbjct: 3349 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPD-PVAAPYCYTRDPSVRWEYC 3406
Query: 1673 DIPQC 1687
++ QC
Sbjct: 3407 NLTQC 3411
Score = 499 bits (1285), Expect = e-141
Identities = 246/545 (45%), Positives = 311/545 (57%), Gaps = 80/545 (14%)
Frame = +2
Query: 293 EKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRN 472
E+R + EC GNG++YRGT S T +G CQ WS +PH +PE +P AGL NYCRN
Sbjct: 2528 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 2587
Query: 473 PDNDEKGPWCYTTDPETRFDYCDIPECED------------------------------- 559
PD P+CYT DP R++YC++ +C D
Sbjct: 2588 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 2646
Query: 560 --ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEP 733
EC H +G+ Y G S T++G CQ+W S +PH+H P +PN L MNYCRNPD
Sbjct: 2647 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 2706
Query: 734 RPWCFTTDPNKRWEFCDIPRCT------------TPPPT------SGPTYQ------CLK 841
P+C+T DP RWE+C++ +C+ TP P+ PT Q C
Sbjct: 2707 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 2766
Query: 842 GRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYT 1021
G G++YRGT S T +G TCQ WS+ +PH H+RTPE +P L NYCRNPD AP+CYT
Sbjct: 2767 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 2826
Query: 1022 TDSEVRWDYCKIPSCGSS---------TTSTEHLDAP---VPPEQTPVAQDCYRGNGESY 1165
D VRW+YC + C + T L+AP P EQ P Q+CY GNG+SY
Sbjct: 2827 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 2886
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVR 1345
RGT STT+TGR CQ+W SMTPH H +TP +PNAGL MNYCRNPDA +P+CYT DP VR
Sbjct: 2887 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 2946
Query: 1346 WEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-----------DCMFGNGKRYRGKRAT 1492
WEYCNL +CS+ E P + VPS+E SE +C GNG+ YRG +T
Sbjct: 2947 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 3006
Query: 1493 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 1672
TV G CQ W++ PH HS TPE P AGL NYCRNPD P+CYT +P ++YC
Sbjct: 3007 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 3064
Query: 1673 DIPQC 1687
++ QC
Sbjct: 3065 NLTQC 3069
Score = 499 bits (1285), Expect = e-141
Identities = 246/545 (45%), Positives = 311/545 (57%), Gaps = 80/545 (14%)
Frame = +2
Query: 293 EKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRN 472
E+R + EC GNG++YRGT S T +G CQ WS +PH +PE +P AGL NYCRN
Sbjct: 2186 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 2245
Query: 473 PDNDEKGPWCYTTDPETRFDYCDIPECED------------------------------- 559
PD P+CYT DP R++YC++ +C D
Sbjct: 2246 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 2304
Query: 560 --ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEP 733
EC H +G+ Y G S T++G CQ+W S +PH+H P +PN L MNYCRNPD
Sbjct: 2305 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 2364
Query: 734 RPWCFTTDPNKRWEFCDIPRCT------------TPPPT------SGPTYQ------CLK 841
P+C+T DP RWE+C++ +C+ TP P+ PT Q C
Sbjct: 2365 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 2424
Query: 842 GRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYT 1021
G G++YRGT S T +G TCQ WS+ +PH H+RTPE +P L NYCRNPD AP+CYT
Sbjct: 2425 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 2484
Query: 1022 TDSEVRWDYCKIPSCGSS---------TTSTEHLDAP---VPPEQTPVAQDCYRGNGESY 1165
D VRW+YC + C + T L+AP P EQ P Q+CY GNG+SY
Sbjct: 2485 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 2544
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVR 1345
RGT STT+TGR CQ+W SMTPH H +TP +PNAGL MNYCRNPDA +P+CYT DP VR
Sbjct: 2545 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 2604
Query: 1346 WEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-----------DCMFGNGKRYRGKRAT 1492
WEYCNL +CS+ E P + VPS+E SE +C GNG+ YRG +T
Sbjct: 2605 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 2664
Query: 1493 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 1672
TV G CQ W++ PH HS TPE P AGL NYCRNPD P+CYT +P ++YC
Sbjct: 2665 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 2722
Query: 1673 DIPQC 1687
++ QC
Sbjct: 2723 NLTQC 2727
Score = 499 bits (1285), Expect = e-141
Identities = 246/545 (45%), Positives = 311/545 (57%), Gaps = 80/545 (14%)
Frame = +2
Query: 293 EKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRN 472
E+R + EC GNG++YRGT S T +G CQ WS +PH +PE +P AGL NYCRN
Sbjct: 1844 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 1903
Query: 473 PDNDEKGPWCYTTDPETRFDYCDIPECED------------------------------- 559
PD P+CYT DP R++YC++ +C D
Sbjct: 1904 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 1962
Query: 560 --ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEP 733
EC H +G+ Y G S T++G CQ+W S +PH+H P +PN L MNYCRNPD
Sbjct: 1963 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 2022
Query: 734 RPWCFTTDPNKRWEFCDIPRCT------------TPPPT------SGPTYQ------CLK 841
P+C+T DP RWE+C++ +C+ TP P+ PT Q C
Sbjct: 2023 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 2082
Query: 842 GRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYT 1021
G G++YRGT S T +G TCQ WS+ +PH H+RTPE +P L NYCRNPD AP+CYT
Sbjct: 2083 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 2142
Query: 1022 TDSEVRWDYCKIPSCGSS---------TTSTEHLDAP---VPPEQTPVAQDCYRGNGESY 1165
D VRW+YC + C + T L+AP P EQ P Q+CY GNG+SY
Sbjct: 2143 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 2202
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVR 1345
RGT STT+TGR CQ+W SMTPH H +TP +PNAGL MNYCRNPDA +P+CYT DP VR
Sbjct: 2203 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 2262
Query: 1346 WEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-----------DCMFGNGKRYRGKRAT 1492
WEYCNL +CS+ E P + VPS+E SE +C GNG+ YRG +T
Sbjct: 2263 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 2322
Query: 1493 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 1672
TV G CQ W++ PH HS TPE P AGL NYCRNPD P+CYT +P ++YC
Sbjct: 2323 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 2380
Query: 1673 DIPQC 1687
++ QC
Sbjct: 2381 NLTQC 2385
Score = 499 bits (1285), Expect = e-141
Identities = 246/545 (45%), Positives = 311/545 (57%), Gaps = 80/545 (14%)
Frame = +2
Query: 293 EKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRN 472
E+R + EC GNG++YRGT S T +G CQ WS +PH +PE +P AGL NYCRN
Sbjct: 1502 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 1561
Query: 473 PDNDEKGPWCYTTDPETRFDYCDIPECED------------------------------- 559
PD P+CYT DP R++YC++ +C D
Sbjct: 1562 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 1620
Query: 560 --ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEP 733
EC H +G+ Y G S T++G CQ+W S +PH+H P +PN L MNYCRNPD
Sbjct: 1621 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 1680
Query: 734 RPWCFTTDPNKRWEFCDIPRCT------------TPPPT------SGPTYQ------CLK 841
P+C+T DP RWE+C++ +C+ TP P+ PT Q C
Sbjct: 1681 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 1740
Query: 842 GRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYT 1021
G G++YRGT S T +G TCQ WS+ +PH H+RTPE +P L NYCRNPD AP+CYT
Sbjct: 1741 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 1800
Query: 1022 TDSEVRWDYCKIPSCGSS---------TTSTEHLDAP---VPPEQTPVAQDCYRGNGESY 1165
D VRW+YC + C + T L+AP P EQ P Q+CY GNG+SY
Sbjct: 1801 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 1860
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVR 1345
RGT STT+TGR CQ+W SMTPH H +TP +PNAGL MNYCRNPDA +P+CYT DP VR
Sbjct: 1861 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 1920
Query: 1346 WEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-----------DCMFGNGKRYRGKRAT 1492
WEYCNL +CS+ E P + VPS+E SE +C GNG+ YRG +T
Sbjct: 1921 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 1980
Query: 1493 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 1672
TV G CQ W++ PH HS TPE P AGL NYCRNPD P+CYT +P ++YC
Sbjct: 1981 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 2038
Query: 1673 DIPQC 1687
++ QC
Sbjct: 2039 NLTQC 2043
Score = 499 bits (1285), Expect = e-141
Identities = 246/545 (45%), Positives = 311/545 (57%), Gaps = 80/545 (14%)
Frame = +2
Query: 293 EKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRN 472
E+R + EC GNG++YRGT S T +G CQ WS +PH +PE +P AGL NYCRN
Sbjct: 1160 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 1219
Query: 473 PDNDEKGPWCYTTDPETRFDYCDIPECED------------------------------- 559
PD P+CYT DP R++YC++ +C D
Sbjct: 1220 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 1278
Query: 560 --ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEP 733
EC H +G+ Y G S T++G CQ+W S +PH+H P +PN L MNYCRNPD
Sbjct: 1279 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 1338
Query: 734 RPWCFTTDPNKRWEFCDIPRCT------------TPPPT------SGPTYQ------CLK 841
P+C+T DP RWE+C++ +C+ TP P+ PT Q C
Sbjct: 1339 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 1398
Query: 842 GRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYT 1021
G G++YRGT S T +G TCQ WS+ +PH H+RTPE +P L NYCRNPD AP+CYT
Sbjct: 1399 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 1458
Query: 1022 TDSEVRWDYCKIPSCGSS---------TTSTEHLDAP---VPPEQTPVAQDCYRGNGESY 1165
D VRW+YC + C + T L+AP P EQ P Q+CY GNG+SY
Sbjct: 1459 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 1518
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVR 1345
RGT STT+TGR CQ+W SMTPH H +TP +PNAGL MNYCRNPDA +P+CYT DP VR
Sbjct: 1519 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 1578
Query: 1346 WEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-----------DCMFGNGKRYRGKRAT 1492
WEYCNL +CS+ E P + VPS+E SE +C GNG+ YRG +T
Sbjct: 1579 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 1638
Query: 1493 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 1672
TV G CQ W++ PH HS TPE P AGL NYCRNPD P+CYT +P ++YC
Sbjct: 1639 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 1696
Query: 1673 DIPQC 1687
++ QC
Sbjct: 1697 NLTQC 1701
Score = 499 bits (1285), Expect = e-141
Identities = 246/545 (45%), Positives = 311/545 (57%), Gaps = 80/545 (14%)
Frame = +2
Query: 293 EKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRN 472
E+R + EC GNG++YRGT S T +G CQ WS +PH +PE +P AGL NYCRN
Sbjct: 818 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 877
Query: 473 PDNDEKGPWCYTTDPETRFDYCDIPECED------------------------------- 559
PD P+CYT DP R++YC++ +C D
Sbjct: 878 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 936
Query: 560 --ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEP 733
EC H +G+ Y G S T++G CQ+W S +PH+H P +PN L MNYCRNPD
Sbjct: 937 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 996
Query: 734 RPWCFTTDPNKRWEFCDIPRCT------------TPPPT------SGPTYQ------CLK 841
P+C+T DP RWE+C++ +C+ TP P+ PT Q C
Sbjct: 997 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 1056
Query: 842 GRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYT 1021
G G++YRGT S T +G TCQ WS+ +PH H+RTPE +P L NYCRNPD AP+CYT
Sbjct: 1057 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 1116
Query: 1022 TDSEVRWDYCKIPSCGSS---------TTSTEHLDAP---VPPEQTPVAQDCYRGNGESY 1165
D VRW+YC + C + T L+AP P EQ P Q+CY GNG+SY
Sbjct: 1117 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 1176
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVR 1345
RGT STT+TGR CQ+W SMTPH H +TP +PNAGL MNYCRNPDA +P+CYT DP VR
Sbjct: 1177 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 1236
Query: 1346 WEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-----------DCMFGNGKRYRGKRAT 1492
WEYCNL +CS+ E P + VPS+E SE +C GNG+ YRG +T
Sbjct: 1237 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 1296
Query: 1493 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 1672
TV G CQ W++ PH HS TPE P AGL NYCRNPD P+CYT +P ++YC
Sbjct: 1297 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 1354
Query: 1673 DIPQC 1687
++ QC
Sbjct: 1355 NLTQC 1359
Score = 499 bits (1285), Expect = e-141
Identities = 246/545 (45%), Positives = 311/545 (57%), Gaps = 80/545 (14%)
Frame = +2
Query: 293 EKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRN 472
E+R + EC GNG++YRGT S T +G CQ WS +PH +PE +P AGL NYCRN
Sbjct: 476 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 535
Query: 473 PDNDEKGPWCYTTDPETRFDYCDIPECED------------------------------- 559
PD P+CYT DP R++YC++ +C D
Sbjct: 536 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 594
Query: 560 --ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEP 733
EC H +G+ Y G S T++G CQ+W S +PH+H P +PN L MNYCRNPD
Sbjct: 595 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 654
Query: 734 RPWCFTTDPNKRWEFCDIPRCT------------TPPPT------SGPTYQ------CLK 841
P+C+T DP RWE+C++ +C+ TP P+ PT Q C
Sbjct: 655 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 714
Query: 842 GRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYT 1021
G G++YRGT S T +G TCQ WS+ +PH H+RTPE +P L NYCRNPD AP+CYT
Sbjct: 715 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 774
Query: 1022 TDSEVRWDYCKIPSCGSS---------TTSTEHLDAP---VPPEQTPVAQDCYRGNGESY 1165
D VRW+YC + C + T L+AP P EQ P Q+CY GNG+SY
Sbjct: 775 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 834
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVR 1345
RGT STT+TGR CQ+W SMTPH H +TP +PNAGL MNYCRNPDA +P+CYT DP VR
Sbjct: 835 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 894
Query: 1346 WEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-----------DCMFGNGKRYRGKRAT 1492
WEYCNL +CS+ E P + VPS+E SE +C GNG+ YRG +T
Sbjct: 895 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 954
Query: 1493 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 1672
TV G CQ W++ PH HS TPE P AGL NYCRNPD P+CYT +P ++YC
Sbjct: 955 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 1012
Query: 1673 DIPQC 1687
++ QC
Sbjct: 1013 NLTQC 1017
Score = 499 bits (1285), Expect = e-141
Identities = 246/545 (45%), Positives = 311/545 (57%), Gaps = 80/545 (14%)
Frame = +2
Query: 293 EKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRN 472
E+R + EC GNG++YRGT S T +G CQ WS +PH +PE +P AGL NYCRN
Sbjct: 134 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 193
Query: 473 PDNDEKGPWCYTTDPETRFDYCDIPECED------------------------------- 559
PD P+CYT DP R++YC++ +C D
Sbjct: 194 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 252
Query: 560 --ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEP 733
EC H +G+ Y G S T++G CQ+W S +PH+H P +PN L MNYCRNPD
Sbjct: 253 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 312
Query: 734 RPWCFTTDPNKRWEFCDIPRCT------------TPPPT------SGPTYQ------CLK 841
P+C+T DP RWE+C++ +C+ TP P+ PT Q C
Sbjct: 313 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 372
Query: 842 GRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYT 1021
G G++YRGT S T +G TCQ WS+ +PH H+RTPE +P L NYCRNPD AP+CYT
Sbjct: 373 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 432
Query: 1022 TDSEVRWDYCKIPSCGSS---------TTSTEHLDAP---VPPEQTPVAQDCYRGNGESY 1165
D VRW+YC + C + T L+AP P EQ P Q+CY GNG+SY
Sbjct: 433 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 492
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVR 1345
RGT STT+TGR CQ+W SMTPH H +TP +PNAGL MNYCRNPDA +P+CYT DP VR
Sbjct: 493 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 552
Query: 1346 WEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-----------DCMFGNGKRYRGKRAT 1492
WEYCNL +CS+ E P + VPS+E SE +C GNG+ YRG +T
Sbjct: 553 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 612
Query: 1493 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 1672
TV G CQ W++ PH HS TPE P AGL NYCRNPD P+CYT +P ++YC
Sbjct: 613 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 670
Query: 1673 DIPQC 1687
++ QC
Sbjct: 671 NLTQC 675
Score = 498 bits (1282), Expect = e-140
Identities = 240/538 (44%), Positives = 309/538 (57%), Gaps = 73/538 (13%)
Frame = +2
Query: 293 EKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRN 472
E+R + EC GNG++YRGT S T +G CQ WS +PH +PE +P AGL NYCRN
Sbjct: 3326 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 3385
Query: 473 PDNDEKGPWCYTTDPETRFDYCDIPECED------------------------------- 559
PD P+CYT DP R++YC++ +C D
Sbjct: 3386 PD-PVAAPYCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPG 3444
Query: 560 --ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEP 733
EC H +G+ Y+G T++G CQ+W S +PH+H P+ +PN L NYCRNPD
Sbjct: 3445 VQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVA 3504
Query: 734 RPWCFTTDPNKRWEFCDIPRCT-------TPP------------------PTSGPTYQCL 838
PWC+TTDP+ RWE+C++ RC+ PP T G C
Sbjct: 3505 APWCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPG-VQDCY 3563
Query: 839 KGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCY 1018
G++YRGT S T +G TCQ WS+ +PH+H+RTPEN+P L NYCRNPD E PWCY
Sbjct: 3564 YHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEIRPWCY 3623
Query: 1019 TTDSEVRWDYCKIPSCGSSTTS------------TEHLDAPVPPEQTPVAQDCYRGNGES 1162
T D VRW+YC + C + +S TE P EQ+P QDCY G+G+S
Sbjct: 3624 TMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYHGDGQS 3683
Query: 1163 YRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRV 1342
YRG+ STT+TGR CQSW SMTPH H++T +PN GLT NYCRNPDA+ SPWCYT DP V
Sbjct: 3684 YRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEISPWCYTMDPNV 3743
Query: 1343 RWEYCNLKKCSETEQQV--TNFPAIAQVPSVEDLS-EDCMFGNGKRYRGKRATTVAGVPC 1513
RWEYCNL +C TE V T+ Q P+ + + +DC G+G+ YRG +TTV G C
Sbjct: 3744 RWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGSFSTTVTGRTC 3803
Query: 1514 QEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDIPQC 1687
Q W++ PH H T E P GL +NYCRNPD + PWCYT +P ++YC++ QC
Sbjct: 3804 QSWSSMTPHWHQ-RTTEYYPNGGLTRNYCRNPDAEIR-PWCYTMDPSVRWEYCNLTQC 3859
Score = 497 bits (1280), Expect = e-140
Identities = 244/545 (44%), Positives = 309/545 (56%), Gaps = 80/545 (14%)
Frame = +2
Query: 293 EKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRN 472
E+R + EC GNG++YRGT S T +G CQ WS +PH +PE +P AGL NYCRN
Sbjct: 2984 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 3043
Query: 473 PDNDEKGPWCYTTDPETRFDYCDIPECED------------------------------- 559
PD P+CYT DP R++YC++ +C D
Sbjct: 3044 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 3102
Query: 560 --ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEP 733
EC H +G+ Y G S T++G CQ+W S +PH+H P +PN L MNYCRNPD
Sbjct: 3103 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 3162
Query: 734 RPWCFTTDPNKRWEFCDIPRCT------------TPPPT------SGPTYQ------CLK 841
P+C+T DP RWE+C++ +C+ TP P+ PT Q C
Sbjct: 3163 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 3222
Query: 842 GRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYT 1021
G G++YRGT S T +G TCQ WS+ +PH H+RTPE +P L NYCRNPD AP+CYT
Sbjct: 3223 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 3282
Query: 1022 TDSEVRWDYCKIPSCGSS---------TTSTEHLDAP---VPPEQTPVAQDCYRGNGESY 1165
D VRW+YC + C + T L+AP P EQ P Q+CY GNG+SY
Sbjct: 3283 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 3342
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVR 1345
RGT STT+TGR CQ+W SMTPH H +TP +PNAGL MNYCRNPD +P+CYT DP VR
Sbjct: 3343 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVAAPYCYTRDPSVR 3402
Query: 1346 WEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-----------DCMFGNGKRYRGKRAT 1492
WEYCNL +CS+ E P I +PS+E SE +C GNG+ Y+G
Sbjct: 3403 WEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQSYQGTYFI 3462
Query: 1493 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 1672
TV G CQ W++ PH HS TP P AGL KNYCRNPD PWCYTT+P ++YC
Sbjct: 3463 TVTGRTCQAWSSMTPHSHS-RTPAYYPNAGLIKNYCRNPD-PVAAPWCYTTDPSVRWEYC 3520
Query: 1673 DIPQC 1687
++ +C
Sbjct: 3521 NLTRC 3525
Score = 493 bits (1270), Expect = e-139
Identities = 241/550 (43%), Positives = 308/550 (56%), Gaps = 81/550 (14%)
Frame = +2
Query: 293 EKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRN 472
E+R + EC GNG++YRGT S T +G CQ WS +PH +PE +P AGL NYCRN
Sbjct: 3212 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 3271
Query: 473 PDNDEKGPWCYTTDPETRFDYCDIPECED------------------------------- 559
PD P+CYT DP R++YC++ +C D
Sbjct: 3272 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 3330
Query: 560 --ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEP 733
EC H +G+ Y G S T++G CQ+W S +PH+H P +PN L MNYCRNPD
Sbjct: 3331 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVA 3390
Query: 734 RPWCFTTDPNKRWEFCDIPRCT------TPPPTSGP------------------TYQCLK 841
P+C+T DP+ RWE+C++ +C+ PPT P +C
Sbjct: 3391 APYCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYH 3450
Query: 842 GRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYT 1021
G G++Y+GT +T +G TCQ WS+ +PH H+RTP +P L +NYCRNPD APWCYT
Sbjct: 3451 GNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVAAPWCYT 3510
Query: 1022 TDSEVRWDYCKIPSCGSS------------TTSTEHLDAPVPPEQTPVAQDCYRGNGESY 1165
TD VRW+YC + C + S E E+TP QDCY G+SY
Sbjct: 3511 TDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSY 3570
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVR 1345
RGT STT+TGR CQ+W SMTPH+H +TP N+PNAGLT NYCRNPDA+ PWCYT DP VR
Sbjct: 3571 RGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEIRPWCYTMDPSVR 3630
Query: 1346 WEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-----------DCMFGNGKRYRGKRAT 1492
WEYCNL +C TE V + PS E SE DC G+G+ YRG +T
Sbjct: 3631 WEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYHGDGQSYRGSFST 3690
Query: 1493 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 1672
TV G CQ W++ PH H T E P GL +NYCRNPD + + PWCYT +P ++YC
Sbjct: 3691 TVTGRTCQSWSSMTPHWHQ-RTTEYYPNGGLTRNYCRNPDAEIS-PWCYTMDPNVRWEYC 3748
Query: 1673 DIPQC-VTSS 1699
++ QC VT S
Sbjct: 3749 NLTQCPVTES 3758
Score = 492 bits (1266), Expect = e-139
Identities = 240/545 (44%), Positives = 307/545 (56%), Gaps = 80/545 (14%)
Frame = +2
Query: 293 EKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRN 472
E+ + +C G+G++YRGT S T +G CQ WS +PH + E +P AGL NYCRN
Sbjct: 20 EQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRN 79
Query: 473 PDNDEKGPWCYTTDPETRFDYCDIPECED------------------------------- 559
PD P+CYT DP R++YC++ +C D
Sbjct: 80 PD-AVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
Query: 560 --ECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEP 733
EC H +G+ Y G S T++G CQ+W S +PH+H P +PN L MNYCRNPD
Sbjct: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
Query: 734 RPWCFTTDPNKRWEFCDIPRCT------TPPPTSGP------------------TYQCLK 841
P+C+T DP RWE+C++ +C+ PPT P +C
Sbjct: 199 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 258
Query: 842 GRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYT 1021
G G++YRGT S T +G TCQ WS+ +PH H+RTPE +P L NYCRNPD AP+CYT
Sbjct: 259 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 318
Query: 1022 TDSEVRWDYCKIPSCGS---------STTSTEHLDAP---VPPEQTPVAQDCYRGNGESY 1165
D VRW+YC + C + T L+AP P EQ P Q+CY GNG+SY
Sbjct: 319 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 378
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVR 1345
RGT STT+TGR CQ+W SMTPH H +TP +PNAGL MNYCRNPDA +P+CYT DP VR
Sbjct: 379 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 438
Query: 1346 WEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-----------DCMFGNGKRYRGKRAT 1492
WEYCNL +CS+ E P + VPS+E SE +C GNG+ YRG +T
Sbjct: 439 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 498
Query: 1493 TVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYC 1672
TV G CQ W++ PH HS TPE P AGL NYCRNPD P+CYT +P ++YC
Sbjct: 499 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 556
Query: 1673 DIPQC 1687
++ QC
Sbjct: 557 NLTQC 561
Score = 339 bits (870), Expect = 6e-93
Identities = 161/317 (50%), Positives = 196/317 (61%), Gaps = 23/317 (7%)
Frame = +2
Query: 806 PPTSGPTYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCR 985
P S C G G++YRGT S T +G TCQ WS+ +PH+HNRT EN+P L NYCR
Sbjct: 19 PEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCR 78
Query: 986 NPDGETAPWCYTTDSEVRWDYCKIPSCGSS---------TTSTEHLDAP---VPPEQTPV 1129
NPD AP+CYT D VRW+YC + C + T L+AP P EQ P
Sbjct: 79 NPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
Query: 1130 AQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADK 1309
Q+CY GNG+SYRGT STT+TGR CQ+W SMTPH H +TP +PNAGL MNYCRNPDA
Sbjct: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
Query: 1310 SPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-----------DCMF 1456
+P+CYT DP VRWEYCNL +CS+ E P + VPS+E SE +C
Sbjct: 199 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 258
Query: 1457 GNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWC 1636
GNG+ YRG +TTV G CQ W++ PH HS TPE P AGL NYCRNPD P+C
Sbjct: 259 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYC 316
Query: 1637 YTTNPQKLFDYCDIPQC 1687
YT +P ++YC++ QC
Sbjct: 317 YTRDPGVRWEYCNLTQC 333
>ref|XP_946885.1| PREDICTED: similar to Apolipoprotein(a) precursor (Apo(a)) (Lp(a))
[Homo sapiens]
Length = 440
Score = 613 bits (1580), Expect = e-175
Identities = 283/378 (74%), Positives = 314/378 (83%), Gaps = 1/378 (0%)
Frame = +2
Query: 1277 MNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-DCM 1453
MNYCRNPDAD PWC+T DP +RWEYCNL +CS+TE V P + QVPS+ SE DCM
Sbjct: 1 MNYCRNPDADTGPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCM 60
Query: 1454 FGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPW 1633
FGNGK YRGK+ATTV G PCQEWAAQEPHRHS F P TN AGLEKNYCRNPDGD NGPW
Sbjct: 61 FGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPW 120
Query: 1634 CYTTNPQKLFDYCDIPQCVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRY 1813
CYT NP+KLFDYCDIP C +SSFDCGKP+VEPKKCP +VGGCV+ PHSWPWQVSLR R+
Sbjct: 121 CYTMNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRF 180
Query: 1814 RGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLFKEPS 1993
HFCGGTLISPEWVLTA HCL+KSS PSSYKVILGAH+E +L VQEI+VS+LF EP+
Sbjct: 181 GKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPT 240
Query: 1994 GADIALLKLSSPAVITDQVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLKEARLP 2173
ADIALLKLS PAVITD+V+PACLP+P+Y+V RT CYITGWGET+GT+G GLLKEA+L
Sbjct: 241 QADIALLKLSRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLL 300
Query: 2174 VIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGL 2353
VIEN+VCN Y+Y +CA HLA G DSCQGDSGGPLVCFEKDKYILQGVTSWGL
Sbjct: 301 VIENEVCNHYKY---------ICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL 351
Query: 2354 GCALPNKPGVYVRVSRFV 2407
GCA PNKPGVY RVSR +
Sbjct: 352 GCARPNKPGVYARVSRMI 369
Score = 149 bits (376), Expect = 1e-35
Identities = 65/140 (46%), Positives = 82/140 (58%), Gaps = 4/140 (2%)
Frame = +2
Query: 974 NYCRNPDGETAPWCYTTDSEVRWDYCKIPSCGSS--TTSTEHLDAPVPPEQTPVAQDCYR 1147
NYCRNPD +T PWC+T D +RW+YC + C + T VP P QDC
Sbjct: 2 NYCRNPDADTGPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMF 61
Query: 1148 GNGESYRGTSSTTITGRKCQSWVSMTPHRHEK-TPGNFPNAGLTMNYCRNPDAD-KSPWC 1321
GNG+ YRG +TT+TG CQ W + PHRH PG AGL NYCRNPD D PWC
Sbjct: 62 GNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWC 121
Query: 1322 YTTDPRVRWEYCNLKKCSET 1381
YT +PR ++YC++ C+ +
Sbjct: 122 YTMNPRKLFDYCDIPLCASS 141
Score = 142 bits (359), Expect = 1e-33
Identities = 66/142 (46%), Positives = 86/142 (60%), Gaps = 16/142 (11%)
Frame = +2
Query: 701 MNYCRNPDGEPRPWCFTTDPNKRWEFCDIPRCT-------TPP-----PTSGPTYQ--CL 838
MNYCRNPD + PWCFT DP+ RWE+C++ RC+ PP P+ GP + C+
Sbjct: 1 MNYCRNPDADTGPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCM 60
Query: 839 KGRGENYRGTVSVTASGHTCQRWSAQSPHKHNR-TPENFPCKNLEENYCRNPDGE-TAPW 1012
G G+ YRG + T +G CQ W+AQ PH+H+ P LE+NYCRNPDG+ PW
Sbjct: 61 FGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPW 120
Query: 1013 CYTTDSEVRWDYCKIPSCGSST 1078
CYT + +DYC IP C SS+
Sbjct: 121 CYTMNPRKLFDYCDIPLCASSS 142
Score = 124 bits (311), Expect = 4e-28
Identities = 56/140 (40%), Positives = 78/140 (55%), Gaps = 25/140 (17%)
Frame = +2
Query: 458 NYCRNPDNDEKGPWCYTTDPETRFDYCDIPECED-----------------------ECM 568
NYCRNPD D GPWC+T DP R++YC++ C D +CM
Sbjct: 2 NYCRNPDADT-GPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCM 60
Query: 569 HCSGEHYEGKISKTMSGIECQSWGSQSPHAHG-YLPSKFPNKNLKMNYCRNPDGEPR-PW 742
+G+ Y GK + T++G CQ W +Q PH H ++P L+ NYCRNPDG+ PW
Sbjct: 61 FGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPW 120
Query: 743 CFTTDPNKRWEFCDIPRCTT 802
C+T +P K +++CDIP C +
Sbjct: 121 CYTMNPRKLFDYCDIPLCAS 140
Score = 103 bits (257), Expect = 8e-22
Identities = 46/96 (47%), Positives = 54/96 (56%), Gaps = 1/96 (1%)
Frame = +2
Query: 314 ECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPK-YSPEKFPLAGLEENYCRNPDNDEK 490
+C GNGK YRG + T +G CQ+W+ PH + P AGLE+NYCRNPD D
Sbjct: 58 DCMFGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDIN 117
Query: 491 GPWCYTTDPETRFDYCDIPECEDECMHCSGEHYEGK 598
GPWCYT +P FDYCDIP C C E K
Sbjct: 118 GPWCYTMNPRKLFDYCDIPLCASSSFDCGKPQVEPK 153
>ref|XP_931416.1| PREDICTED: similar to Apolipoprotein(a) precursor (Apo(a)) (Lp(a))
[Homo sapiens]
Length = 440
Score = 613 bits (1580), Expect = e-175
Identities = 283/378 (74%), Positives = 314/378 (83%), Gaps = 1/378 (0%)
Frame = +2
Query: 1277 MNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSE-DCM 1453
MNYCRNPDAD PWC+T DP +RWEYCNL +CS+TE V P + QVPS+ SE DCM
Sbjct: 1 MNYCRNPDADTGPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCM 60
Query: 1454 FGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPW 1633
FGNGK YRGK+ATTV G PCQEWAAQEPHRHS F P TN AGLEKNYCRNPDGD NGPW
Sbjct: 61 FGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPW 120
Query: 1634 CYTTNPQKLFDYCDIPQCVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRY 1813
CYT NP+KLFDYCDIP C +SSFDCGKP+VEPKKCP +VGGCV+ PHSWPWQVSLR R+
Sbjct: 121 CYTMNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRF 180
Query: 1814 RGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLFKEPS 1993
HFCGGTLISPEWVLTA HCL+KSS PSSYKVILGAH+E +L VQEI+VS+LF EP+
Sbjct: 181 GKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPT 240
Query: 1994 GADIALLKLSSPAVITDQVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLKEARLP 2173
ADIALLKLS PAVITD+V+PACLP+P+Y+V RT CYITGWGET+GT+G GLLKEA+L
Sbjct: 241 QADIALLKLSRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLL 300
Query: 2174 VIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGL 2353
VIEN+VCN Y+Y +CA HLA G DSCQGDSGGPLVCFEKDKYILQGVTSWGL
Sbjct: 301 VIENEVCNHYKY---------ICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL 351
Query: 2354 GCALPNKPGVYVRVSRFV 2407
GCA PNKPGVY RVSR +
Sbjct: 352 GCARPNKPGVYARVSRMI 369
Score = 149 bits (376), Expect = 1e-35
Identities = 65/140 (46%), Positives = 82/140 (58%), Gaps = 4/140 (2%)
Frame = +2
Query: 974 NYCRNPDGETAPWCYTTDSEVRWDYCKIPSCGSS--TTSTEHLDAPVPPEQTPVAQDCYR 1147
NYCRNPD +T PWC+T D +RW+YC + C + T VP P QDC
Sbjct: 2 NYCRNPDADTGPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMF 61
Query: 1148 GNGESYRGTSSTTITGRKCQSWVSMTPHRHEK-TPGNFPNAGLTMNYCRNPDAD-KSPWC 1321
GNG+ YRG +TT+TG CQ W + PHRH PG AGL NYCRNPD D PWC
Sbjct: 62 GNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWC 121
Query: 1322 YTTDPRVRWEYCNLKKCSET 1381
YT +PR ++YC++ C+ +
Sbjct: 122 YTMNPRKLFDYCDIPLCASS 141
Score = 142 bits (359), Expect = 1e-33
Identities = 66/142 (46%), Positives = 86/142 (60%), Gaps = 16/142 (11%)
Frame = +2
Query: 701 MNYCRNPDGEPRPWCFTTDPNKRWEFCDIPRCT-------TPP-----PTSGPTYQ--CL 838
MNYCRNPD + PWCFT DP+ RWE+C++ RC+ PP P+ GP + C+
Sbjct: 1 MNYCRNPDADTGPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCM 60
Query: 839 KGRGENYRGTVSVTASGHTCQRWSAQSPHKHNR-TPENFPCKNLEENYCRNPDGE-TAPW 1012
G G+ YRG + T +G CQ W+AQ PH+H+ P LE+NYCRNPDG+ PW
Sbjct: 61 FGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPW 120
Query: 1013 CYTTDSEVRWDYCKIPSCGSST 1078
CYT + +DYC IP C SS+
Sbjct: 121 CYTMNPRKLFDYCDIPLCASSS 142
Score = 124 bits (311), Expect = 4e-28
Identities = 56/140 (40%), Positives = 78/140 (55%), Gaps = 25/140 (17%)
Frame = +2
Query: 458 NYCRNPDNDEKGPWCYTTDPETRFDYCDIPECED-----------------------ECM 568
NYCRNPD D GPWC+T DP R++YC++ C D +CM
Sbjct: 2 NYCRNPDADT-GPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCM 60
Query: 569 HCSGEHYEGKISKTMSGIECQSWGSQSPHAHG-YLPSKFPNKNLKMNYCRNPDGEPR-PW 742
+G+ Y GK + T++G CQ W +Q PH H ++P L+ NYCRNPDG+ PW
Sbjct: 61 FGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPW 120
Query: 743 CFTTDPNKRWEFCDIPRCTT 802
C+T +P K +++CDIP C +
Sbjct: 121 CYTMNPRKLFDYCDIPLCAS 140
Score = 103 bits (257), Expect = 8e-22
Identities = 46/96 (47%), Positives = 54/96 (56%), Gaps = 1/96 (1%)
Frame = +2
Query: 314 ECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPK-YSPEKFPLAGLEENYCRNPDNDEK 490
+C GNGK YRG + T +G CQ+W+ PH + P AGLE+NYCRNPD D
Sbjct: 58 DCMFGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDIN 117
Query: 491 GPWCYTTDPETRFDYCDIPECEDECMHCSGEHYEGK 598
GPWCYT +P FDYCDIP C C E K
Sbjct: 118 GPWCYTMNPRKLFDYCDIPLCASSSFDCGKPQVEPK 153
>ref|NP_000592.3| hepatocyte growth factor isoform 1 preproprotein [Homo sapiens]
Length = 728
Score = 507 bits (1306), Expect = e-143
Identities = 265/650 (40%), Positives = 362/650 (55%), Gaps = 20/650 (3%)
Frame = +2
Query: 539 DIPECEDECMHC---SGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNY 709
D+ E +D +C G Y+G +S T SGI+CQ W S PH H +LPS + K+L+ NY
Sbjct: 117 DLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENY 176
Query: 710 CRNPDGEPR-PWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVTAS 886
CRNP GE PWCFT++P R+E CDIP+C+ +C+ GE+YRG + T S
Sbjct: 177 CRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSE--------VECMTCNGESYRGLMDHTES 228
Query: 887 GHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVRWDYCKIPSC 1066
G CQRW Q+PH+H PE +P K ++NYCRNPDG+ PWCYT D RW+YC I +C
Sbjct: 229 GKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 288
Query: 1067 GSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKT 1246
+T + D VP E T +C +G GE YRGT +T G CQ W S PH H+ T
Sbjct: 289 ADNTMN----DTDVPLETT----ECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMT 340
Query: 1247 PGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPS 1426
P NF L NYCRNPD +SPWC+TTDP +R YC+ Q+P+
Sbjct: 341 PENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVGYCS------------------QIPN 382
Query: 1427 VE-DLSEDCMFGNGKRYRGKRATTVAGVPCQEWAA--QEPHRHSIFTPETNPRAGLEKNY 1597
+ +DC GNGK Y G + T +G+ C W ++ HRH + P+ + L +NY
Sbjct: 383 CDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASK---LNENY 439
Query: 1598 CRNPDGDDNGPWCYTTNPQKLFDYCDIPQCVTSS-----------FDCGKPKVEPKKCPA 1744
CRNPD D +GPWCYT NP +DYC I +C + C K K
Sbjct: 440 CRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTK------QL 493
Query: 1745 RVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGA 1924
RVV G + + W VSLRYR + H CGG+LI WVLTA+ C S Y+ LG
Sbjct: 494 RVVNG-IPTRTNIGWMVSLRYRNK-HICGGSLIKESWVLTARQCFP-SRDLKDYEAWLGI 550
Query: 1925 HEEHHLGEGV--QEIDVSKLFKEPSGADIALLKLSSPAVITDQVIPACLPTPNYVVADRT 2098
H+ H G+ Q ++VS+L P G+D+ L+KL+ PAV+ D V LP + ++T
Sbjct: 551 HDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLPNYGCTIPEKT 610
Query: 2099 ACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSCQ 2278
+C + GWG T GLL+ A L ++ N+ C+++ ++ E+CAG G C+
Sbjct: 611 SCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCE 670
Query: 2279 GDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIM 2428
GD GGPLVC + ++ GV G GCA+PN+PG++VRV+ + WI +I+
Sbjct: 671 GDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 720
Score = 405 bits (1042), Expect = e-113
Identities = 191/441 (43%), Positives = 258/441 (58%), Gaps = 12/441 (2%)
Frame = +2
Query: 113 SLSRKQVAARSVEECAAKCEAETN--FICRAFQYHSKDQQCVVMAENSKTSPIARM--RD 280
+L K + ++CA +C F C+AF + +QC+ NS +S + + +
Sbjct: 56 ALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHE 115
Query: 281 VVLFEKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEEN 460
L+E + Y+ C G G++Y+GT S TKSG+ CQ WS PH + P + L+EN
Sbjct: 116 FDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQEN 175
Query: 461 YCRNPDNDEKGPWCYTTDPETRFDYCDIPEC-EDECMHCSGEHYEGKISKTMSGIECQSW 637
YCRNP +E GPWC+T++PE R++ CDIP+C E ECM C+GE Y G + T SG CQ W
Sbjct: 176 YCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRW 235
Query: 638 GSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEPRPWCFTTDPNKRWEFCDIPRC--TTPPP 811
Q+PH H +LP ++P+K NYCRNPDG+PRPWC+T DP+ RWE+C I C T
Sbjct: 236 DHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMND 295
Query: 812 TSGP--TYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCR 985
T P T +C++G+GE YRGTV+ +G CQRW +Q PH+H+ TPENF CK+L ENYCR
Sbjct: 296 TDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCR 355
Query: 986 NPDGETAPWCYTTDSEVRWDYC-KIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGES 1162
NPDG +PWC+TTD +R YC +IP+C S QDCYRGNG++
Sbjct: 356 NPDGSESPWCFTTDPNIRVGYCSQIPNCDMSH-----------------GQDCYRGNGKN 398
Query: 1163 YRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDAD-KSPWCYTTDPR 1339
Y G S T +G C W H + L NYCRNPD D PWCYT +P
Sbjct: 399 YMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPL 458
Query: 1340 VRWEYCNLKKC-SETEQQVTN 1399
+ W+YC + +C +T + N
Sbjct: 459 IPWDYCPISRCEGDTTPTIVN 479
>ref|NP_001010932.1| hepatocyte growth factor isoform 3 precursor [Homo sapiens]
Length = 723
Score = 496 bits (1276), Expect = e-140
Identities = 263/650 (40%), Positives = 358/650 (55%), Gaps = 20/650 (3%)
Frame = +2
Query: 539 DIPECEDECMHC---SGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNY 709
D+ E +D +C G Y+G +S T SGI+CQ W S PH H Y K+L+ NY
Sbjct: 117 DLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYR-----GKDLQENY 171
Query: 710 CRNPDGEPR-PWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVTAS 886
CRNP GE PWCFT++P R+E CDIP+C+ +C+ GE+YRG + T S
Sbjct: 172 CRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSE--------VECMTCNGESYRGLMDHTES 223
Query: 887 GHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVRWDYCKIPSC 1066
G CQRW Q+PH+H PE +P K ++NYCRNPDG+ PWCYT D RW+YC I +C
Sbjct: 224 GKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 283
Query: 1067 GSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKT 1246
+T + D VP E T +C +G GE YRGT +T G CQ W S PH H+ T
Sbjct: 284 ADNTMN----DTDVPLETT----ECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMT 335
Query: 1247 PGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPS 1426
P NF L NYCRNPD +SPWC+TTDP +R YC+ Q+P+
Sbjct: 336 PENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVGYCS------------------QIPN 377
Query: 1427 VE-DLSEDCMFGNGKRYRGKRATTVAGVPCQEWAA--QEPHRHSIFTPETNPRAGLEKNY 1597
+ +DC GNGK Y G + T +G+ C W ++ HRH + P+ + L +NY
Sbjct: 378 CDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASK---LNENY 434
Query: 1598 CRNPDGDDNGPWCYTTNPQKLFDYCDIPQCVTSS-----------FDCGKPKVEPKKCPA 1744
CRNPD D +GPWCYT NP +DYC I +C + C K K
Sbjct: 435 CRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTK------QL 488
Query: 1745 RVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGA 1924
RVV G + + W VSLRYR + H CGG+LI WVLTA+ C S Y+ LG
Sbjct: 489 RVVNG-IPTRTNIGWMVSLRYRNK-HICGGSLIKESWVLTARQCFP-SRDLKDYEAWLGI 545
Query: 1925 HEEHHLGEGV--QEIDVSKLFKEPSGADIALLKLSSPAVITDQVIPACLPTPNYVVADRT 2098
H+ H G+ Q ++VS+L P G+D+ L+KL+ PAV+ D V LP + ++T
Sbjct: 546 HDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLPNYGCTIPEKT 605
Query: 2099 ACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSCQ 2278
+C + GWG T GLL+ A L ++ N+ C+++ ++ E+CAG G C+
Sbjct: 606 SCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCE 665
Query: 2279 GDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIM 2428
GD GGPLVC + ++ GV G GCA+PN+PG++VRV+ + WI +I+
Sbjct: 666 GDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 715
Score = 400 bits (1027), Expect = e-111
Identities = 191/441 (43%), Positives = 257/441 (58%), Gaps = 12/441 (2%)
Frame = +2
Query: 113 SLSRKQVAARSVEECAAKCEAETN--FICRAFQYHSKDQQCVVMAENSKTSPIARM--RD 280
+L K + ++CA +C F C+AF + +QC+ NS +S + + +
Sbjct: 56 ALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHE 115
Query: 281 VVLFEKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEEN 460
L+E + Y+ C G G++Y+GT S TKSG+ CQ WS PH Y + L+EN
Sbjct: 116 FDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKD-----LQEN 170
Query: 461 YCRNPDNDEKGPWCYTTDPETRFDYCDIPEC-EDECMHCSGEHYEGKISKTMSGIECQSW 637
YCRNP +E GPWC+T++PE R++ CDIP+C E ECM C+GE Y G + T SG CQ W
Sbjct: 171 YCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRW 230
Query: 638 GSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEPRPWCFTTDPNKRWEFCDIPRC--TTPPP 811
Q+PH H +LP ++P+K NYCRNPDG+PRPWC+T DP+ RWE+C I C T
Sbjct: 231 DHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMND 290
Query: 812 TSGP--TYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCR 985
T P T +C++G+GE YRGTV+ +G CQRW +Q PH+H+ TPENF CK+L ENYCR
Sbjct: 291 TDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCR 350
Query: 986 NPDGETAPWCYTTDSEVRWDYC-KIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGES 1162
NPDG +PWC+TTD +R YC +IP+C S QDCYRGNG++
Sbjct: 351 NPDGSESPWCFTTDPNIRVGYCSQIPNCDMSH-----------------GQDCYRGNGKN 393
Query: 1163 YRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDAD-KSPWCYTTDPR 1339
Y G S T +G C W H + L NYCRNPD D PWCYT +P
Sbjct: 394 YMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPL 453
Query: 1340 VRWEYCNLKKC-SETEQQVTN 1399
+ W+YC + +C +T + N
Sbjct: 454 IPWDYCPISRCEGDTTPTIVN 474
Score = 259 bits (663), Expect = 6e-69
Identities = 126/281 (44%), Positives = 153/281 (54%), Gaps = 16/281 (5%)
Frame = +2
Query: 314 ECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRNPDNDEKG 493
EC T NG++YRG T+SG ICQ+W +PH K+ PE++P G ++NYCRNPD +
Sbjct: 205 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 263
Query: 494 PWCYTTDPETRFDYCDIPECED-------------ECMHCSGEHYEGKISKTMSGIECQS 634
PWCYT DP TR++YC I C D EC+ GE Y G ++ +GI CQ
Sbjct: 264 PWCYTLDPHTRWEYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQR 323
Query: 635 WGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEPRPWCFTTDPNKRWEFC-DIPRCTTPPP 811
W SQ PH H P F K+L+ NYCRNPDG PWCFTTDPN R +C IP C
Sbjct: 324 WDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVGYCSQIPNC----- 378
Query: 812 TSGPTYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNP 991
C +G G+NY G +S T SG TC W H L ENYCRNP
Sbjct: 379 DMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNP 438
Query: 992 DGET-APWCYTTDSEVRWDYCKIPSCGSSTTST-EHLDAPV 1108
D + PWCYT + + WDYC I C TT T +LD PV
Sbjct: 439 DDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPV 479
>ref|NP_066278.2| macrophage stimulating 1 (hepatocyte growth factor-like) [Homo
sapiens]
Length = 711
Score = 492 bits (1267), Expect = e-139
Identities = 260/672 (38%), Positives = 360/672 (53%), Gaps = 26/672 (3%)
Frame = +2
Query: 494 PWCYTTDPETRF---DYCDIPECED---ECMHCSGEHYEGKISKTMSGIECQSWGSQSPH 655
PW + P TR CD+ + +D C+ +G Y G ++ T+ G+ CQ+W + P+
Sbjct: 82 PWTQHS-PHTRLRRSGRCDLFQKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPN 140
Query: 656 AHGYLPSKFPNKNLKMNYCRNPDGEPR-PWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQ 832
H Y P+ L+ N+CRNPDG+P PWC+TTDP R++ C I C
Sbjct: 141 DHKYTPTL--RNGLEENFCRNPDGDPGGPWCYTTDPAVRFQSCGIKSCREAA-------- 190
Query: 833 CLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPW 1012
C+ GE YRG V T SG CQRW Q PH+H P F + L++NYCRNPDG PW
Sbjct: 191 CVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSERPW 250
Query: 1013 CYTTDSEVRWDYCKIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTIT 1192
CYTTD ++ ++C +P CGS P Q C+RG GE YRGT++TT
Sbjct: 251 CYTTDPQIEREFCDLPRCGSEAQ----------PRQEATTVSCFRGKGEGYRGTANTTTA 300
Query: 1193 GRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYC-NLKK 1369
G CQ W + PH+H TP + L N+CRNPD ++PWC+T P +R +C +++
Sbjct: 301 GVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFTLRPGMRAAFCYQIRR 360
Query: 1370 CSETEQQVTNFPAIAQVPSVEDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHS 1549
C++ + +DC G G++YRG + T GV CQ W+A+ PH+
Sbjct: 361 CTDDVRP-----------------QDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQ 403
Query: 1550 IFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCDIPQCVTSS---------- 1699
FT + P A LE+N+CRNPDGD +GPWCYT +P+ FDYC + +C
Sbjct: 404 -FTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCALRRCADDQPPSILDPPDQ 462
Query: 1700 --FD-CGK--PKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLT 1864
F+ CGK +++ ++ RVVGG P + PW VSLR R HFCGG+L+ +W+LT
Sbjct: 463 VQFEKCGKRVDRLDQRRSKLRVVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILT 519
Query: 1865 AKHCLEKSSSP-SSYKVILGA--HEEHHLGEGVQEIDVSKLFKEPSGADIALLKLSSPAV 2035
A+ C P + Y+V LG H +Q + V+K+ PSG+ + LLKL
Sbjct: 520 ARQCFSSCHMPLTGYEVWLGTLFQNPQHGEPSLQRVPVAKMVCGPSGSQLVLLKLERSVT 579
Query: 2036 ITDQVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLD 2215
+ +V CLP YVV T C I GWGETKGT +L A L VI N+ CN
Sbjct: 580 LNQRVALICLPPEWYVVPPGTKCEIAGWGETKGTGNDTVLNVALLNVISNQECNIKH--R 637
Query: 2216 GKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRV 2395
G+V E+C L + +C+GD GGPL CF + ++L+G+ CA P V+ RV
Sbjct: 638 GRVRESEMCTEGLLAPVGACEGDYGGPLACFTHNCWVLEGIIIPNRVCARSRWPAVFTRV 697
Query: 2396 SRFVTWIEEIMR 2431
S FV WI ++MR
Sbjct: 698 SVFVDWIHKVMR 709
Score = 396 bits (1017), Expect = e-110
Identities = 199/449 (44%), Positives = 252/449 (56%), Gaps = 8/449 (1%)
Frame = +2
Query: 149 EECAAKCEAETNFICRAFQYHSKDQQCVVM--AENSKTSPIARMRDVVLFEKRIYLSECK 322
EECA +C + CRAF Y+ C ++ ++S + + R LF+K+ Y+ C
Sbjct: 54 EECAGRCGPLMD--CRAFHYNVSSHGCQLLPWTQHSPHTRLRRSGRCDLFQKKDYVRTCI 111
Query: 323 TGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRNPDNDEKGPWC 502
NG YRGT + T G+ CQ WS P+ KY+P GLEEN+CRNPD D GPWC
Sbjct: 112 MNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTL--RNGLEENFCRNPDGDPGGPWC 169
Query: 503 YTTDPETRFDYCDIPEC-EDECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSK 679
YTTDP RF C I C E C+ C+GE Y G + +T SG ECQ W Q PH H + P K
Sbjct: 170 YTTDPAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGK 229
Query: 680 FPNKNLKMNYCRNPDGEPRPWCFTTDPNKRWEFCDIPRC--TTPPPTSGPTYQCLKGRGE 853
F ++ L NYCRNPDG RPWC+TTDP EFCD+PRC P T C +G+GE
Sbjct: 230 FLDQGLDDNYCRNPDGSERPWCYTTDPQIEREFCDLPRCGSEAQPRQEATTVSCFRGKGE 289
Query: 854 NYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSE 1033
YRGT + T +G CQRW AQ PH+H TPE + CK+L EN+CRNPDG APWC+T
Sbjct: 290 GYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFTLRPG 349
Query: 1034 VRWDYC-KIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQS 1210
+R +C +I C QDCY G GE YRGT S T G +CQ
Sbjct: 350 MRAAFCYQIRRCTDDVR----------------PQDCYHGAGEQYRGTVSKTRKGVQCQR 393
Query: 1211 WVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADK-SPWCYTTDPRVRWEYCNLKKCSETEQ 1387
W + TPH+ + T + P+A L N+CRNPD D PWCYT DPR ++YC L++C++
Sbjct: 394 WSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCALRRCADD-- 451
Query: 1388 QVTNFPAIAQVPSVEDLSEDCMFGN-GKR 1471
Q PS+ D + F GKR
Sbjct: 452 ---------QPPSILDPPDQVQFEKCGKR 471
>ref|NP_127509.1| plasminogen activator, tissue type isoform 3 precursor [Homo sapiens]
Length = 516
Score = 243 bits (620), Expect = 6e-64
Identities = 165/464 (35%), Positives = 225/464 (48%), Gaps = 33/464 (7%)
Frame = +2
Query: 1139 CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNA---GL-TMNYCRNPDAD 1306
CY G SYRGT ST +G +C +W S + + G P+A GL NYCRNPD D
Sbjct: 81 CYEDQGISYRGTWSTAESGAECTNWNS-SALAQKPYSGRRPDAIRLGLGNHNYCRNPDRD 139
Query: 1307 KSPWCYTTDP-RVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSEDCMFGNGKRYRGK 1483
PWCY + E+C+ CSE + DC FGNG YRG
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSEG-------------------NSDCYFGNGSAYRGT 180
Query: 1484 RATTVAGVPCQEWAAQEPHRHSIFTPETNPRA---GLEK-NYCRNPDGDDNGPWCYTTNP 1651
+ T +G C W + ++T + NP A GL K NYCRNPDGD PWC+
Sbjct: 181 HSLTESGASCLPWNSMILIG-KVYTAQ-NPSAQALGLGKHNYCRNPDGDAK-PWCHVLKN 237
Query: 1652 QKL-FDYCDIPQCVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGH-- 1822
++L ++YCD+P C T CG + + R+ GG + S PWQ ++ ++R
Sbjct: 238 RRLTWEYCDVPSCST----CGLRQYSQPQF--RIKGGLFADIASHPWQAAIFAKHRRSPG 291
Query: 1823 ---FCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLF---- 1981
CGG LIS W+L+A HC ++ P VILG GE Q+ +V K
Sbjct: 292 ERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKE 351
Query: 1982 --KEPSGADIALLKLSSPAVITDQ----VIPACLPTPNYVVADRTACYITGWG--ETKGT 2137
+ DIALL+L S + Q V CLP + + D T C ++G+G E
Sbjct: 352 FDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSP 411
Query: 2138 YGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGG------IDSCQGDSGGPL 2299
+ + LKEA + + + C L+ V+ LCAG G D+CQGDSGGPL
Sbjct: 412 FYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPL 471
Query: 2300 VCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIMR 2431
VC + L G+ SWGLGC + PGVY +V+ ++ WI + MR
Sbjct: 472 VCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMR 515
Score = 121 bits (304), Expect = 3e-27
Identities = 68/190 (35%), Positives = 90/190 (47%), Gaps = 9/190 (4%)
Frame = +2
Query: 833 CLKGRGENYRGTVSVTASGHTCQRWS----AQSPHKHNRTPENFPCKNLEENYCRNPDGE 1000
C + +G +YRGT S SG C W+ AQ P+ R P+ NYCRNPD +
Sbjct: 81 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYS-GRRPDAIRLGLGNHNYCRNPDRD 139
Query: 1001 TAPWCYTTDS-EVRWDYCKIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTS 1177
+ PWCY + + ++C P+C + DCY GNG +YRGT
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSEGNS------------------DCYFGNGSAYRGTH 181
Query: 1178 STTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTM---NYCRNPDADKSPWCYT-TDPRVR 1345
S T +G C W SM T N L + NYCRNPD D PWC+ + R+
Sbjct: 182 SLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLT 241
Query: 1346 WEYCNLKKCS 1375
WEYC++ CS
Sbjct: 242 WEYCDVPSCS 251
Score = 117 bits (293), Expect = 5e-26
Identities = 80/237 (33%), Positives = 106/237 (44%), Gaps = 15/237 (6%)
Frame = +2
Query: 317 CKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYS---PEKFPLAGLEENYCRNPDNDE 487
C G +YRGT S +SG C W+ S+ YS P+ L NYCRNPD D
Sbjct: 81 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDS 140
Query: 488 KGPWCYTTDP-ETRFDYCDIPECED---ECMHCSGEHYEGKISKTMSGIECQSWGSQSPH 655
K PWCY + ++C P C + +C +G Y G S T SG C W S
Sbjct: 141 K-PWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILI 199
Query: 656 AHGYLPSKFPNKNL---KMNYCRNPDGEPRPWCFTTDPNKR--WEFCDIPRCTT--PPPT 814
Y + L K NYCRNPDG+ +PWC N+R WE+CD+P C+T
Sbjct: 200 GKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVL-KNRRLTWEYCDVPSCSTCGLRQY 258
Query: 815 SGPTYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTP-ENFPCKNLEENYC 982
S P ++ +G + + H W A KH R+P E F C + + C
Sbjct: 259 SQPQFR--------IKGGLFADIASHP---WQAAIFAKHRRSPGERFLCGGILISSC 304
Score = 114 bits (286), Expect = 3e-25
Identities = 67/188 (35%), Positives = 89/188 (47%), Gaps = 9/188 (4%)
Frame = +2
Query: 536 CDIPECEDECMHCSGEHYEGKISKTMSGIECQSWGS----QSPHAHGYLPSKFPNKNLKM 703
C+I + C G Y G S SG EC +W S Q P++ G P
Sbjct: 73 CEI-DTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYS-GRRPDAIRLGLGNH 130
Query: 704 NYCRNPDGEPRPWCFTTDPNK-RWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVT 880
NYCRNPD + +PWC+ K EFC P C S C G G YRGT S+T
Sbjct: 131 NYCRNPDRDSKPWCYVFKAGKYSSEFCSTPAC------SEGNSDCYFGNGSAYRGTHSLT 184
Query: 881 ASGHTCQRWSAQSPHKHNRTPENFPCKNL---EENYCRNPDGETAPWCYTTDSE-VRWDY 1048
SG +C W++ T +N + L + NYCRNPDG+ PWC+ + + W+Y
Sbjct: 185 ESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEY 244
Query: 1049 CKIPSCGS 1072
C +PSC +
Sbjct: 245 CDVPSCST 252
Score = 67.0 bits (162), Expect = 8e-11
Identities = 39/86 (45%), Positives = 49/86 (56%), Gaps = 5/86 (5%)
Frame = +2
Query: 311 SECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLA---GL-EENYCRNPD 478
S+C GNG YRGT S T+SG C W+ S I K + P A GL + NYCRNPD
Sbjct: 167 SDCYFGNGSAYRGTHSLTESGASCLPWN-SMILIGKVYTAQNPSAQALGLGKHNYCRNPD 225
Query: 479 NDEKGPWCYT-TDPETRFDYCDIPEC 553
D K PWC+ + ++YCD+P C
Sbjct: 226 GDAK-PWCHVLKNRRLTWEYCDVPSC 250
>ref|NP_000921.1| plasminogen activator, tissue type isoform 1 preproprotein [Homo
sapiens]
Length = 562
Score = 243 bits (620), Expect = 6e-64
Identities = 165/464 (35%), Positives = 225/464 (48%), Gaps = 33/464 (7%)
Frame = +2
Query: 1139 CYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNA---GL-TMNYCRNPDAD 1306
CY G SYRGT ST +G +C +W S + + G P+A GL NYCRNPD D
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNS-SALAQKPYSGRRPDAIRLGLGNHNYCRNPDRD 185
Query: 1307 KSPWCYTTDP-RVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSEDCMFGNGKRYRGK 1483
PWCY + E+C+ CSE + DC FGNG YRG
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSEG-------------------NSDCYFGNGSAYRGT 226
Query: 1484 RATTVAGVPCQEWAAQEPHRHSIFTPETNPRA---GLEK-NYCRNPDGDDNGPWCYTTNP 1651
+ T +G C W + ++T + NP A GL K NYCRNPDGD PWC+
Sbjct: 227 HSLTESGASCLPWNSMILIG-KVYTAQ-NPSAQALGLGKHNYCRNPDGDAK-PWCHVLKN 283
Query: 1652 QKL-FDYCDIPQCVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGH-- 1822
++L ++YCD+P C T CG + + R+ GG + S PWQ ++ ++R
Sbjct: 284 RRLTWEYCDVPSCST----CGLRQYSQPQF--RIKGGLFADIASHPWQAAIFAKHRRSPG 337
Query: 1823 ---FCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLF---- 1981
CGG LIS W+L+A HC ++ P VILG GE Q+ +V K
Sbjct: 338 ERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKE 397
Query: 1982 --KEPSGADIALLKLSSPAVITDQ----VIPACLPTPNYVVADRTACYITGWG--ETKGT 2137
+ DIALL+L S + Q V CLP + + D T C ++G+G E
Sbjct: 398 FDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSP 457
Query: 2138 YGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGG------IDSCQGDSGGPL 2299
+ + LKEA + + + C L+ V+ LCAG G D+CQGDSGGPL
Sbjct: 458 FYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPL 517
Query: 2300 VCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIMR 2431
VC + L G+ SWGLGC + PGVY +V+ ++ WI + MR
Sbjct: 518 VCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMR 561
Score = 121 bits (304), Expect = 3e-27
Identities = 68/190 (35%), Positives = 90/190 (47%), Gaps = 9/190 (4%)
Frame = +2
Query: 833 CLKGRGENYRGTVSVTASGHTCQRWS----AQSPHKHNRTPENFPCKNLEENYCRNPDGE 1000
C + +G +YRGT S SG C W+ AQ P+ R P+ NYCRNPD +
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYS-GRRPDAIRLGLGNHNYCRNPDRD 185
Query: 1001 TAPWCYTTDS-EVRWDYCKIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTS 1177
+ PWCY + + ++C P+C + DCY GNG +YRGT
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSEGNS------------------DCYFGNGSAYRGTH 227
Query: 1178 STTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTM---NYCRNPDADKSPWCYT-TDPRVR 1345
S T +G C W SM T N L + NYCRNPD D PWC+ + R+
Sbjct: 228 SLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLT 287
Query: 1346 WEYCNLKKCS 1375
WEYC++ CS
Sbjct: 288 WEYCDVPSCS 297
Score = 117 bits (293), Expect = 5e-26
Identities = 80/237 (33%), Positives = 106/237 (44%), Gaps = 15/237 (6%)
Frame = +2
Query: 317 CKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYS---PEKFPLAGLEENYCRNPDNDE 487
C G +YRGT S +SG C W+ S+ YS P+ L NYCRNPD D
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDS 186
Query: 488 KGPWCYTTDP-ETRFDYCDIPECED---ECMHCSGEHYEGKISKTMSGIECQSWGSQSPH 655
K PWCY + ++C P C + +C +G Y G S T SG C W S
Sbjct: 187 K-PWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILI 245
Query: 656 AHGYLPSKFPNKNL---KMNYCRNPDGEPRPWCFTTDPNKR--WEFCDIPRCTT--PPPT 814
Y + L K NYCRNPDG+ +PWC N+R WE+CD+P C+T
Sbjct: 246 GKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVL-KNRRLTWEYCDVPSCSTCGLRQY 304
Query: 815 SGPTYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTP-ENFPCKNLEENYC 982
S P ++ +G + + H W A KH R+P E F C + + C
Sbjct: 305 SQPQFR--------IKGGLFADIASHP---WQAAIFAKHRRSPGERFLCGGILISSC 350
Score = 114 bits (286), Expect = 3e-25
Identities = 67/188 (35%), Positives = 89/188 (47%), Gaps = 9/188 (4%)
Frame = +2
Query: 536 CDIPECEDECMHCSGEHYEGKISKTMSGIECQSWGS----QSPHAHGYLPSKFPNKNLKM 703
C+I + C G Y G S SG EC +W S Q P++ G P
Sbjct: 119 CEI-DTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYS-GRRPDAIRLGLGNH 176
Query: 704 NYCRNPDGEPRPWCFTTDPNK-RWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVT 880
NYCRNPD + +PWC+ K EFC P C S C G G YRGT S+T
Sbjct: 177 NYCRNPDRDSKPWCYVFKAGKYSSEFCSTPAC------SEGNSDCYFGNGSAYRGTHSLT 230
Query: 881 ASGHTCQRWSAQSPHKHNRTPENFPCKNL---EENYCRNPDGETAPWCYTTDSE-VRWDY 1048
SG +C W++ T +N + L + NYCRNPDG+ PWC+ + + W+Y
Sbjct: 231 ESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEY 290
Query: 1049 CKIPSCGS 1072
C +PSC +
Sbjct: 291 CDVPSCST 298
Score = 67.0 bits (162), Expect = 8e-11
Identities = 39/86 (45%), Positives = 49/86 (56%), Gaps = 5/86 (5%)
Frame = +2
Query: 311 SECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLA---GL-EENYCRNPD 478
S+C GNG YRGT S T+SG C W+ S I K + P A GL + NYCRNPD
Sbjct: 213 SDCYFGNGSAYRGTHSLTESGASCLPWN-SMILIGKVYTAQNPSAQALGLGKHNYCRNPD 271
Query: 479 NDEKGPWCYT-TDPETRFDYCDIPEC 553
D K PWC+ + ++YCD+P C
Sbjct: 272 GDAK-PWCHVLKNRRLTWEYCDVPSC 296
>ref|NP_001010931.1| hepatocyte growth factor isoform 2 precursor [Homo sapiens]
Length = 290
Score = 234 bits (596), Expect = 4e-61
Identities = 102/235 (43%), Positives = 144/235 (61%), Gaps = 5/235 (2%)
Frame = +2
Query: 113 SLSRKQVAARSVEECAAKCEAETN--FICRAFQYHSKDQQCVVMAENSKTSPIARM--RD 280
+L K + ++CA +C F C+AF + +QC+ NS +S + + +
Sbjct: 56 ALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHE 115
Query: 281 VVLFEKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEEN 460
L+E + Y+ C G G++Y+GT S TKSG+ CQ WS PH + P + L+EN
Sbjct: 116 FDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQEN 175
Query: 461 YCRNPDNDEKGPWCYTTDPETRFDYCDIPECED-ECMHCSGEHYEGKISKTMSGIECQSW 637
YCRNP +E GPWC+T++PE R++ CDIP+C + ECM C+GE Y G + T SG CQ W
Sbjct: 176 YCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRW 235
Query: 638 GSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEPRPWCFTTDPNKRWEFCDIPRCTT 802
Q+PH H +LP ++P+K NYCRNPDG+PRPWC+T DP+ RWE+C I C T
Sbjct: 236 DHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 290
Score = 197 bits (501), Expect = 4e-50
Identities = 86/180 (47%), Positives = 113/180 (62%), Gaps = 4/180 (2%)
Frame = +2
Query: 539 DIPECEDECMHC---SGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNY 709
D+ E +D +C G Y+G +S T SGI+CQ W S PH H +LPS + K+L+ NY
Sbjct: 117 DLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENY 176
Query: 710 CRNPDGEPR-PWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVTAS 886
CRNP GE PWCFT++P R+E CDIP+C+ +C+ GE+YRG + T S
Sbjct: 177 CRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSE--------VECMTCNGESYRGLMDHTES 228
Query: 887 GHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVRWDYCKIPSC 1066
G CQRW Q+PH+H PE +P K ++NYCRNPDG+ PWCYT D RW+YC I +C
Sbjct: 229 GKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 288
Score = 189 bits (479), Expect = 1e-47
Identities = 83/181 (45%), Positives = 107/181 (59%), Gaps = 1/181 (0%)
Frame = +2
Query: 833 CLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETA-P 1009
C+ G+G +Y+GTVS+T SG CQ WS+ PH+H+ P ++ K+L+ENYCRNP GE P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
Query: 1010 WCYTTDSEVRWDYCKIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTI 1189
WC+T++ EVR++ C IP C +C NGESYRG T
Sbjct: 188 WCFTSNPEVRYEVCDIPQCSEV--------------------ECMTCNGESYRGLMDHTE 227
Query: 1190 TGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKK 1369
+G+ CQ W TPHRH+ P +P+ G NYCRNPD PWCYT DP RWEYC +K
Sbjct: 228 SGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKT 287
Query: 1370 C 1372
C
Sbjct: 288 C 288
Score = 166 bits (420), Expect = 1e-40
Identities = 82/194 (42%), Positives = 103/194 (53%), Gaps = 1/194 (0%)
Frame = +2
Query: 1115 EQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRN 1294
E ++C G G SY+GT S T +G KCQ W SM PH H P ++ L NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
Query: 1295 PDADK-SPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSEDCMFGNGKR 1471
P ++ PWC+T++P VR+E C++ +CSE E CM NG+
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE---------------------CMTCNGES 218
Query: 1472 YRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNP 1651
YRG T +G CQ W Q PHRH F PE P G + NYCRNPDG PWCYT +P
Sbjct: 219 YRGLMDHTESGKICQRWDHQTPHRHK-FLPERYPDKGFDDNYCRNPDGQPR-PWCYTLDP 276
Query: 1652 QKLFDYCDIPQCVT 1693
++YC I C T
Sbjct: 277 HTRWEYCAIKTCET 290
Score = 99.8 bits (247), Expect = 1e-20
Identities = 40/93 (43%), Positives = 61/93 (65%)
Frame = +2
Query: 1430 EDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNP 1609
+D +C+ G G+ Y+G + T +G+ CQ W++ PH HS F P + L++NYCRNP
Sbjct: 122 KDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-FLPSSYRGKDLQENYCRNP 180
Query: 1610 DGDDNGPWCYTTNPQKLFDYCDIPQCVTSSFDC 1708
G++ GPWC+T+NP+ ++ CDIPQC S +C
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQC--SEVEC 211
Database: RefSeqHP
Posted date: Aug 2, 2006 12:57 AM
Number of letters in database: 17,774,539
Number of sequences in database: 39,411
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 121,603,217
Number of Sequences: 39411
Number of extensions: 3796260
Number of successful extensions: 16251
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 9715
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 15007
length of database: 17,774,539
effective HSP length: 111
effective length of database: 13,399,918
effective search space used: 10585935220
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqMP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= LVRM1_0045_D02
(2705 letters)
Database: RefSeqMP
45,328 sequences; 21,768,885 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_032903.2| plasminogen [Mus musculus] 1377 0.0
Alignment gi|NP_034557.2| hepatocyte growth factor [Mus musculus] 505 e-143
Alignment gi|NP_032269.2| macrophage stimulating 1 (hepatocyte growth fac... 498 e-140
Alignment gi|NP_032898.1| plasminogen activator, tissue [Mus musculus] 237 4e-62
Alignment gi|NP_666213.1| hyaluronic acid binding protein 2 [Mus musculus] 202 1e-51
Alignment gi|NP_067464.1| coagulation factor XII (Hageman factor) [Mus mu... 201 3e-51
Alignment gi|NP_032307.1| hepsin [Mus musculus] 199 1e-50
Alignment gi|NP_542765.1| transmembrane protease, serine 3 [Mus musculus] 197 4e-50
Alignment gi|NP_038949.2| transmembrane protease, serine 8 (intestinal) [... 192 1e-48
Alignment gi|NP_062320.1| hepatocyte growth factor activator [Mus musculus] 188 3e-47
>ref|NP_032903.2| plasminogen [Mus musculus]
Length = 812
Score = 1377 bits (3564), Expect = 0.0
Identities = 619/813 (76%), Positives = 690/813 (84%), Gaps = 4/813 (0%)
Frame = +2
Query: 11 MDHKEVVXXXXXXXXXXXXXXXXXYVNTQGAFLFSLSRKQVAARSVEECAAKCEAETNFI 190
MDHKEV+ Y++TQGA LFSL++KQ+AA V +C AKCE ET+F+
Sbjct: 1 MDHKEVILLFLLLLKPGQGDSLDGYISTQGASLFSLTKKQLAAGGVSDCLAKCEGETDFV 60
Query: 191 CRAFQYHSKDQQCVVMAENSKTSPIARMRDVVLFEKRIYLSECKTGNGKNYRGTTSKTKS 370
CR+FQYHSK+QQCV+MAENSKTS I RMRDV+LFEKR+YLSECKTG G YRGT S+TKS
Sbjct: 61 CRSFQYHSKEQQCVIMAENSKTSSIIRMRDVILFEKRVYLSECKTGIGNGYRGTMSRTKS 120
Query: 371 GVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRNPDNDEKGPWCYTTDPETRFDYCDIPE 550
GV CQKW + PH+P YSP P GLEENYCRNPDNDE+GPWCYTTDP+ R+DYC+IPE
Sbjct: 121 GVACQKWGATFPHVPNYSPSTHPNEGLEENYCRNPDNDEQGPWCYTTDPDKRYDYCNIPE 180
Query: 551 CEDECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGE 730
CE+ECM+CSGE YEGKISKTMSG++CQ+W SQSPHAHGY+P+KFP+KNLKMNYCRNPDGE
Sbjct: 181 CEEECMYCSGEKYEGKISKTMSGLDCQAWDSQSPHAHGYIPAKFPSKNLKMNYCRNPDGE 240
Query: 731 PRPWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVTASGHTCQRWS 910
PRPWCFTTDP KRWE+CDIPRCTTPPP PTYQCLKGRGENYRGTVSVT SG TCQRWS
Sbjct: 241 PRPWCFTTDPTKRWEYCDIPRCTTPPPPPSPTYQCLKGRGENYRGTVSVTVSGKTCQRWS 300
Query: 911 AQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVRWDYCKIPSCGSSTTSTE 1090
Q+PH+HNRTPENFPCKNLEENYCRNPDGETAPWCYTTDS++RW+YC+IPSC SS S +
Sbjct: 301 EQTPHRHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSQLRWEYCEIPSCESS-ASPD 359
Query: 1091 HLDAPVPP-EQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNA 1267
D+ VPP EQTPV Q+CY+ +G+SYRGTSSTTITG+KCQSW +M PHRH KTP NFP+A
Sbjct: 360 QSDSSVPPEEQTPVVQECYQSDGQSYRGTSSTTITGKKCQSWAAMFPHRHSKTPENFPDA 419
Query: 1268 GLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPS-VEDLSE 1444
GL MNYCRNPD DK PWCYTTDP VRWEYCNLK+CSET V P ++Q PS D
Sbjct: 420 GLEMNYCRNPDGDKGPWCYTTDPSVRWEYCNLKRCSETGGSVVELPTVSQEPSGPSDSET 479
Query: 1445 DCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDN 1624
DCM+GNGK YRGK A T AG PCQ WAAQEPHRHSIFTP+TNPRAGLEKNYCRNPDGD N
Sbjct: 480 DCMYGNGKDYRGKTAVTAAGTPCQGWAAQEPHRHSIFTPQTNPRAGLEKNYCRNPDGDVN 539
Query: 1625 GPWCYTTNPQKLFDYCDIPQCVT-SSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSL 1801
GPWCYTTNP+KL+DYCDIP C + SSF+CGKP+VEPKKCP RVVGGCV+ PHSWPWQ+SL
Sbjct: 540 GPWCYTTNPRKLYDYCDIPLCASASSFECGKPQVEPKKCPGRVVGGCVANPHSWPWQISL 599
Query: 1802 RYRYRG-HFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKL 1978
R R+ G HFCGGTLI+PEWVLTA HCLEKSS P YKVILGAHEE+ G VQEI V+KL
Sbjct: 600 RTRFTGQHFCGGTLIAPEWVLTAAHCLEKSSRPEFYKVILGAHEEYIRGSDVQEISVAKL 659
Query: 1979 FKEPSGADIALLKLSSPAVITDQVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLK 2158
EP+ DIALLKLS PA ITD+VIPACLP+PNY+VADRT CYITGWGET+GT+GAG LK
Sbjct: 660 ILEPNNRDIALLKLSRPATITDKVIPACLPSPNYMVADRTICYITGWGETQGTFGAGRLK 719
Query: 2159 EARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGV 2338
EA+LPVIENKVCNR EYL+ +V S ELCAG LAGG+DSCQGDSGGPLVCFEKDKYILQGV
Sbjct: 720 EAQLPVIENKVCNRVEYLNNRVKSTELCAGQLAGGVDSCQGDSGGPLVCFEKDKYILQGV 779
Query: 2339 TSWGLGCALPNKPGVYVRVSRFVTWIEEIMRRN 2437
TSWGLGCA PNKPGVYVRVSRFV WIE MR N
Sbjct: 780 TSWGLGCARPNKPGVYVRVSRFVDWIEREMRNN 812
>ref|NP_034557.2| hepatocyte growth factor [Mus musculus]
Length = 728
Score = 505 bits (1301), Expect = e-143
Identities = 261/651 (40%), Positives = 365/651 (56%), Gaps = 21/651 (3%)
Frame = +2
Query: 539 DIPECEDECMHC---SGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNY 709
D+ E +D +C G Y+G +S T SGI+CQ W S PH H +LPS + K+L+ NY
Sbjct: 118 DLYENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENY 177
Query: 710 CRNPDGEPR-PWCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVTAS 886
CRNP GE PWCFT++P R+E CDIP+C+ +C+ GE+YRG + T S
Sbjct: 178 CRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSE--------VECMTCNGESYRGPMDHTES 229
Query: 887 GHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVRWDYCKIPSC 1066
G TCQRW Q+PH+H PE +P K ++NYCRNPDG+ PWCYT D + W+YC I +C
Sbjct: 230 GKTCQRWDQQTPHRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTTWEYCAIKTC 289
Query: 1067 GSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKT 1246
S + + VP E T +C +G GE YRGTS+T G CQ W S PH+H+ T
Sbjct: 290 AHSAVN----ETDVPMETT----ECIQGQGEGYRGTSNTIWNGIPCQRWDSQYPHKHDIT 341
Query: 1247 PGNFPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEYCNLKKCSETEQQVTNFPAIAQVPS 1426
P NF L NYCRNPD +SPWC+TTDP +R YC+ Q+P
Sbjct: 342 PENFKCKDLRENYCRNPDGAESPWCFTTDPNIRVGYCS------------------QIPK 383
Query: 1427 VEDLS-EDCMFGNGKRYRGKRATTVAGVPCQEWAA--QEPHRHSIFTPETNPRAGLEKNY 1597
+ S +DC GNGK Y G + T +G+ C W ++ HRH + P+ + L KNY
Sbjct: 384 CDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWDKNMEDLHRHIFWEPDASK---LNKNY 440
Query: 1598 CRNPDGDDNGPWCYTTNPQKLFDYCDIPQCVTSS-----------FDCGKPKVEPKKCPA 1744
CRNPD D +GPWCYT NP +DYC I +C + C K K
Sbjct: 441 CRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTK------QL 494
Query: 1745 RVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLTAKHCLE-KSSSPSSYKVILG 1921
RVV G + + W VSL+YR + H CGG+LI WV+TA+ C ++ Y+ LG
Sbjct: 495 RVVNG-IPTQTTVGWMVSLKYRNK-HICGGSLIKESWVITARQCFPARNKDLKDYEAWLG 552
Query: 1922 AHEEHHLGEGVQE--IDVSKLFKEPSGADIALLKLSSPAVITDQVIPACLPTPNYVVADR 2095
H+ H GE ++ +++S+L P G+D+ LLKL+ PA++ + V LP+ + ++
Sbjct: 553 IHDVHERGEEKRKQILNISQLVYGPEGSDLVLLKLARPAILDNFVSTIDLPSYGCTIPEK 612
Query: 2096 TACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSC 2275
T C I GWG T GLL+ A L ++ N+ C+++ ++ ELCAG G C
Sbjct: 613 TTCSIYGWGYTGLINADGLLRVAHLYIMGNEKCSQHHQGKVTLNESELCAGAEKIGSGPC 672
Query: 2276 QGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIM 2428
+GD GGPL+C + ++ GV G GCA+PN+P ++VRV+ + WI +++
Sbjct: 673 EGDYGGPLICEQHKMRMVLGVIVPGRGCAIPNRPVIFVRVAYYAKWIHKVI 723
Score = 397 bits (1021), Expect = e-110
Identities = 189/440 (42%), Positives = 253/440 (57%), Gaps = 12/440 (2%)
Frame = +2
Query: 116 LSRKQVAARSVEECAAKCEAETNFI--CRAFQYHSKDQQCVVMAENSKTSPIARM--RDV 283
L K S +ECA +C F C+AF + ++C NS +S + + +
Sbjct: 58 LKIKTKKVNSADECANRCIRNRGFTFTCKAFVFDKSRKRCYWYPFNSMSSGVKKGFGHEF 117
Query: 284 VLFEKRIYLSECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENY 463
L+E + Y+ C G G +Y+GT S TKSG+ CQ W+ PH + P + L+ENY
Sbjct: 118 DLYENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENY 177
Query: 464 CRNPDNDEKGPWCYTTDPETRFDYCDIPEC-EDECMHCSGEHYEGKISKTMSGIECQSWG 640
CRNP +E GPWC+T++PE R++ CDIP+C E ECM C+GE Y G + T SG CQ W
Sbjct: 178 CRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGPMDHTESGKTCQRWD 237
Query: 641 SQSPHAHGYLPSKFPNKNLKMNYCRNPDGEPRPWCFTTDPNKRWEFCDIPRC--TTPPPT 814
Q+PH H +LP ++P+K NYCRNPDG+PRPWC+T DP+ WE+C I C + T
Sbjct: 238 QQTPHRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTTWEYCAIKTCAHSAVNET 297
Query: 815 SGP--TYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRN 988
P T +C++G+GE YRGT + +G CQRW +Q PHKH+ TPENF CK+L ENYCRN
Sbjct: 298 DVPMETTECIQGQGEGYRGTSNTIWNGIPCQRWDSQYPHKHDITPENFKCKDLRENYCRN 357
Query: 989 PDGETAPWCYTTDSEVRWDYC-KIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESY 1165
PDG +PWC+TTD +R YC +IP C S+ QDCYRGNG++Y
Sbjct: 358 PDGAESPWCFTTDPNIRVGYCSQIPKCDVSS-----------------GQDCYRGNGKNY 400
Query: 1166 RGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDAD-KSPWCYTTDPRV 1342
G S T +G C W H + L NYCRNPD D PWCYT +P +
Sbjct: 401 MGNLSKTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNKNYCRNPDDDAHGPWCYTGNPLI 460
Query: 1343 RWEYCNLKKC-SETEQQVTN 1399
W+YC + +C +T + N
Sbjct: 461 PWDYCPISRCEGDTTPTIVN 480
>ref|NP_032269.2| macrophage stimulating 1 (hepatocyte growth factor-like) [Mus
musculus]
Length = 716
Score = 498 bits (1281), Expect = e-140
Identities = 259/642 (40%), Positives = 362/642 (56%), Gaps = 19/642 (2%)
Frame = +2
Query: 563 CMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMNYCRNPDGEPR-P 739
C+ +G Y G +++T G+ CQ+W + P+ H Y P+ P L+ N+CRNPDG+PR P
Sbjct: 110 CIMDNGVSYRGTVARTAGGLPCQAWSRRFPNDHKYTPT--PKNGLEENFCRNPDGDPRGP 167
Query: 740 WCFTTDPNKRWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSVTASGHTCQRWSAQS 919
WC+TT+ + R++ C I C C+ GE+YRG V VT SG CQRW Q
Sbjct: 168 WCYTTNRSVRFQSCGIKTCREAV--------CVLCNGEDYRGEVDVTESGRECQRWDLQH 219
Query: 920 PHKHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSEVRWDYCKIPSCGSSTTSTEHLD 1099
PH H PE F K+L++NYCRNPDG PWCYTTD V ++C +PSCG + T
Sbjct: 220 PHSHPFQPEKFLDKDLKDNYCRNPDGSERPWCYTTDPNVEREFCDLPSCGPNLPPTVK-G 278
Query: 1100 APVPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTM 1279
+ A +C+RG GE YRGT++TT G CQ W + +PH+H P + L
Sbjct: 279 SKSQRRNKGKALNCFRGKGEDYRGTTNTTSAGVPCQRWDAQSPHQHRFVPEKYACKDLRE 338
Query: 1280 NYCRNPDADKSPWCYTTDPRVRWEYCN-LKKCSETEQQVTNFPAIAQVPSVEDLSEDCMF 1456
N+CRNPD ++PWC+T+ P +R +C+ + +C+E E + E C
Sbjct: 339 NFCRNPDGSEAPWCFTSRPGLRMAFCHQIPRCTE-----------------ELVPEGCYH 381
Query: 1457 GNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWC 1636
G+G++YRG + T GV CQ W+++ PH+ FTP + P+AGLE N+CRNPDGD +GPWC
Sbjct: 382 GSGEQYRGSVSKTRKGVQCQHWSSETPHKPQ-FTPTSAPQAGLEANFCRNPDGDSHGPWC 440
Query: 1637 YTTNPQKLFDYCDIPQC----VTSSFD---------CGKPKVEPKKCPARVVGGCVSIPH 1777
YT +P LFDYC + +C S D CGK +V+ K RVVGG P
Sbjct: 441 YTLDPDILFDYCALQRCDDDQPPSILDPPDQVVFEKCGK-RVD-KSNKLRVVGG---HPG 495
Query: 1778 SWPWQVSLRYRYRGHFCGGTLISPEWVLTAKHCLEKSSSP-SSYKVILGA-HEEHHLGE- 1948
+ PW VSLR R HFCGG+L+ +WVLTA+ C+ P + Y+V LG ++ GE
Sbjct: 496 NSPWTVSLRNRQGQHFCGGSLVKEQWVLTARQCIWSCHEPLTGYEVWLGTINQNPQPGEA 555
Query: 1949 GVQEIDVSKLFKEPSGADIALLKLSSPAVITDQVIPACLPTPNYVVADRTACYITGWGET 2128
+Q + V+K P+G+ + LLKL P ++ V CLP YVV T C I GWGE+
Sbjct: 556 NLQRVPVAKAVCGPAGSQLVLLKLERPVILNHHVALICLPPEQYVVPPGTKCEIAGWGES 615
Query: 2129 KGTYGAGLLKEARLPVIENKVCN-RYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVC 2305
GT +L A + VI N+ CN +Y G + E+C + + +C+GD GGPL C
Sbjct: 616 IGTSNNTVLHVASMNVISNQECNTKYR---GHIQESEICPQGMVVPVGACEGDYGGPLAC 672
Query: 2306 FEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIMR 2431
+ D ++LQG+ CA P P ++ RV FV WI ++M+
Sbjct: 673 YTHDCWVLQGLIIPNRVCARPRWPAIFTRVFVFVDWINKVMQ 714
Score = 410 bits (1053), Expect = e-114
Identities = 207/472 (43%), Positives = 273/472 (57%), Gaps = 18/472 (3%)
Frame = +2
Query: 149 EECAAKCEAETNFICRAFQYHSKDQQCVVM--AENSKTSPIARMRDVVLFEKRIYLSECK 322
EECA +C + CRAF Y+ C ++ ++S + + LF+K+ Y+ C
Sbjct: 54 EECARRCGPLLD--CRAFHYNMSSHGCQLLPWTQHSLHTQLYHSSLCHLFQKKDYVRTCI 111
Query: 323 TGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLAGLEENYCRNPDNDEKGPWC 502
NG +YRGT ++T G+ CQ WS P+ KY+P P GLEEN+CRNPD D +GPWC
Sbjct: 112 MDNGVSYRGTVARTAGGLPCQAWSRRFPNDHKYTPT--PKNGLEENFCRNPDGDPRGPWC 169
Query: 503 YTTDPETRFDYCDIPECEDE-CMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSK 679
YTT+ RF C I C + C+ C+GE Y G++ T SG ECQ W Q PH+H + P K
Sbjct: 170 YTTNRSVRFQSCGIKTCREAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEK 229
Query: 680 FPNKNLKMNYCRNPDGEPRPWCFTTDPNKRWEFCDIPRC-TTPPPT----------SGPT 826
F +K+LK NYCRNPDG RPWC+TTDPN EFCD+P C PPT G
Sbjct: 230 FLDKDLKDNYCRNPDGSERPWCYTTDPNVEREFCDLPSCGPNLPPTVKGSKSQRRNKGKA 289
Query: 827 YQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPDGETA 1006
C +G+GE+YRGT + T++G CQRW AQSPH+H PE + CK+L EN+CRNPDG A
Sbjct: 290 LNCFRGKGEDYRGTTNTTSAGVPCQRWDAQSPHQHRFVPEKYACKDLRENFCRNPDGSEA 349
Query: 1007 PWCYTTDSEVRWDYC-KIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSST 1183
PWC+T+ +R +C +IP C TE L V + CY G+GE YRG+ S
Sbjct: 350 PWCFTSRPGLRMAFCHQIPRC------TEEL----------VPEGCYHGSGEQYRGSVSK 393
Query: 1184 TITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMNYCRNPDADK-SPWCYTTDPRVRWEYCN 1360
T G +CQ W S TPH+ + TP + P AGL N+CRNPD D PWCYT DP + ++YC
Sbjct: 394 TRKGVQCQHWSSETPHKPQFTPTSAPQAGLEANFCRNPDGDSHGPWCYTLDPDILFDYCA 453
Query: 1361 LKKCSETEQQVTNFPAIAQVPSVEDLSEDCMFGN-GKRY-RGKRATTVAGVP 1510
L++C + Q PS+ D + +F GKR + + V G P
Sbjct: 454 LQRCDDD-----------QPPSILDPPDQVVFEKCGKRVDKSNKLRVVGGHP 494
Score = 94.0 bits (232), Expect = 7e-19
Identities = 42/86 (48%), Positives = 52/86 (60%)
Frame = +2
Query: 1430 EDLSEDCMFGNGKRYRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNP 1609
+D C+ NG YRG A T G+PCQ W+ + P+ H +TP P+ GLE+N+CRNP
Sbjct: 104 KDYVRTCIMDNGVSYRGTVARTAGGLPCQAWSRRFPNDHK-YTP--TPKNGLEENFCRNP 160
Query: 1610 DGDDNGPWCYTTNPQKLFDYCDIPQC 1687
DGD GPWCYTTN F C I C
Sbjct: 161 DGDPRGPWCYTTNRSVRFQSCGIKTC 186
>ref|NP_032898.1| plasminogen activator, tissue [Mus musculus]
Length = 559
Score = 237 bits (605), Expect = 4e-62
Identities = 161/466 (34%), Positives = 225/466 (48%), Gaps = 34/466 (7%)
Frame = +2
Query: 1139 CYRGNGESYRGTSSTTITGRKCQSW----VSMTPHRHEKTPGNFPNA---GL-TMNYCRN 1294
C+ G +YRGT ST +G +C +W +S+ P+ + PNA GL NYCRN
Sbjct: 124 CFEEQGITYRGTWSTAESGAECINWNSSVLSLKPYNARR-----PNAIKLGLGNHNYCRN 178
Query: 1295 PDADKSPWCYTTDP-RVRWEYCNLKKCSETEQQVTNFPAIAQVPSVEDLSEDCMFGNGKR 1471
PD D PWCY + E+C+ C + + SEDC G G
Sbjct: 179 PDRDLKPWCYVFKAGKYTTEFCSTPACPKGK------------------SEDCYVGKGVT 220
Query: 1472 YRGKRATTVAGVPCQEWAAQEPHRHSIFTPETNPRA-GLEK-NYCRNPDGDDNGPWCYTT 1645
YRG + T + C W + S TN +A GL + NYCRNPDGD PWC+
Sbjct: 221 YRGTHSLTTSQASCLPWNSIVLMGKSYTAWRTNSQALGLARHNYCRNPDGDAR-PWCHVM 279
Query: 1646 NPQKL-FDYCDIPQCVTSSFDCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGH 1822
+KL ++YCD+ C T CG + K+ R+ GG + S PWQ ++ + +
Sbjct: 280 KDRKLTWEYCDMSPCST----CGLRQY--KRPQFRIKGGLYTDITSHPWQAAIFVKNKRS 333
Query: 1823 -----FCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGAHEEHHLGEGVQEIDVSKLF-- 1981
CGG LIS WVL+A HC + P+ KV+LG GE Q ++ K
Sbjct: 334 PGERFLCGGVLISSCWVLSAAHCFLERFPPNHLKVVLGRTYRVVPGEEEQTFEIEKYIVH 393
Query: 1982 ----KEPSGADIALLKLSSP----AVITDQVIPACLPTPNYVVADRTACYITGWG--ETK 2131
+ DIALL+L S A + V ACLP PN + D T C ++G+G E
Sbjct: 394 EEFDDDTYDNDIALLQLRSQSKQCAQESSSVGTACLPDPNLQLPDWTECELSGYGKHEAS 453
Query: 2132 GTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGG-----IDSCQGDSGGP 2296
+ + LKEA + + + C + V++ LCAG G D+CQGDSGGP
Sbjct: 454 SPFFSDRLKEAHVRLYPSSRCTSQHLFNKTVTNNMLCAGDTRSGGNQDLHDACQGDSGGP 513
Query: 2297 LVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIMRR 2434
LVC + L G+ SWGLGC + PGVY +V+ ++ WI + M++
Sbjct: 514 LVCMINKQMTLTGIISWGLGCGQKDVPGVYTKVTNYLDWIHDNMKQ 559
Score = 111 bits (277), Expect = 5e-24
Identities = 63/189 (33%), Positives = 86/189 (45%), Gaps = 8/189 (4%)
Frame = +2
Query: 833 CLKGRGENYRGTVSVTASGHTCQRWSAQ--SPHKHN-RTPENFPCKNLEENYCRNPDGET 1003
C + +G YRGT S SG C W++ S +N R P NYCRNPD +
Sbjct: 124 CFEEQGITYRGTWSTAESGAECINWNSSVLSLKPYNARRPNAIKLGLGNHNYCRNPDRDL 183
Query: 1004 APWCYTTDS-EVRWDYCKIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSS 1180
PWCY + + ++C P+C + +DCY G G +YRGT S
Sbjct: 184 KPWCYVFKAGKYTTEFCSTPACPKGKS-----------------EDCYVGKGVTYRGTHS 226
Query: 1181 TTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTM---NYCRNPDADKSPWCYT-TDPRVRW 1348
T + C W S+ T + L + NYCRNPD D PWC+ D ++ W
Sbjct: 227 LTTSQASCLPWNSIVLMGKSYTAWRTNSQALGLARHNYCRNPDGDARPWCHVMKDRKLTW 286
Query: 1349 EYCNLKKCS 1375
EYC++ CS
Sbjct: 287 EYCDMSPCS 295
Score = 106 bits (265), Expect = 1e-22
Identities = 65/189 (34%), Positives = 89/189 (47%), Gaps = 10/189 (5%)
Frame = +2
Query: 536 CDIPECEDECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKM---- 703
CDI + C G Y G S SG EC +W S Y ++ PN +K+
Sbjct: 116 CDI-DTRATCFEEQGITYRGTWSTAESGAECINWNSSVLSLKPY-NARRPNA-IKLGLGN 172
Query: 704 -NYCRNPDGEPRPWCFTTDPNK-RWEFCDIPRCTTPPPTSGPTYQCLKGRGENYRGTVSV 877
NYCRNPD + +PWC+ K EFC P C G + C G+G YRGT S+
Sbjct: 173 HNYCRNPDRDLKPWCYVFKAGKYTTEFCSTPACP-----KGKSEDCYVGKGVTYRGTHSL 227
Query: 878 TASGHTCQRWSAQSPHKHNRTPENFPCKNL---EENYCRNPDGETAPWCYT-TDSEVRWD 1045
T S +C W++ + T + L NYCRNPDG+ PWC+ D ++ W+
Sbjct: 228 TTSQASCLPWNSIVLMGKSYTAWRTNSQALGLARHNYCRNPDGDARPWCHVMKDRKLTWE 287
Query: 1046 YCKIPSCGS 1072
YC + C +
Sbjct: 288 YCDMSPCST 296
Score = 104 bits (260), Expect = 4e-22
Identities = 62/174 (35%), Positives = 79/174 (45%), Gaps = 12/174 (6%)
Frame = +2
Query: 317 CKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYS---PEKFPLAGLEENYCRNPDNDE 487
C G YRGT S +SG C W+ S + Y+ P L NYCRNPD D
Sbjct: 124 CFEEQGITYRGTWSTAESGAECINWNSSVLSLKPYNARRPNAIKLGLGNHNYCRNPDRDL 183
Query: 488 KGPWCYTTDP-ETRFDYCDIPEC----EDECMHCSGEHYEGKISKTMSGIECQSWGSQSP 652
K PWCY + ++C P C ++C G Y G S T S C W S
Sbjct: 184 K-PWCYVFKAGKYTTEFCSTPACPKGKSEDCYVGKGVTYRGTHSLTTSQASCLPWNSIVL 242
Query: 653 HAHGYLPSKFPNKNL---KMNYCRNPDGEPRPWCFTTDPNK-RWEFCDIPRCTT 802
Y + ++ L + NYCRNPDG+ RPWC K WE+CD+ C+T
Sbjct: 243 MGKSYTAWRTNSQALGLARHNYCRNPDGDARPWCHVMKDRKLTWEYCDMSPCST 296
Score = 55.8 bits (133), Expect = 2e-07
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 4/84 (4%)
Frame = +2
Query: 314 ECKTGNGKNYRGTTSKTKSGVICQKWS---VSSPHIPKYSPEKFPLAGLEENYCRNPDND 484
+C G G YRGT S T S C W+ + + L NYCRNPD D
Sbjct: 212 DCYVGKGVTYRGTHSLTTSQASCLPWNSIVLMGKSYTAWRTNSQALGLARHNYCRNPDGD 271
Query: 485 EKGPWCYT-TDPETRFDYCDIPEC 553
+ PWC+ D + ++YCD+ C
Sbjct: 272 AR-PWCHVMKDRKLTWEYCDMSPC 294
>ref|NP_666213.1| hyaluronic acid binding protein 2 [Mus musculus]
Length = 517
Score = 202 bits (515), Expect = 1e-51
Identities = 133/373 (35%), Positives = 186/373 (49%), Gaps = 42/373 (11%)
Frame = +2
Query: 1442 EDCMFGNGKRYRGKRATTVAGVPCQEWAAQE--PHRHSIFTPETNPRAGLEKNYCRNPDG 1615
+DC G+G YRGK + TV PC W + +++F + E N+CRNPDG
Sbjct: 149 DDCYVGDGYSYRGKVSKTVNQNPCLYWNSHLLLQETYNMFMEDAETHGIAEHNFCRNPDG 208
Query: 1616 DDNGPWCYT-TNPQKL-FDYCDIPQC--------VTSSFD----------CGKPKVEPKK 1735
D PWC+ N +K+ ++YCD+ C V S + CGK +V +
Sbjct: 209 DHK-PWCFVKVNSEKVKWEYCDVTVCPVPDTPNPVESLLEPVMELPGFESCGKTEVA-EH 266
Query: 1736 CPARVVGGCVSIPHSWPWQVSLRYRY-------RGHFCGGTLISPEWVLTAKHCLEKSSS 1894
R+ GG S PWQVSL+ +GHFCGG LI P WVLTA HC + ++
Sbjct: 267 AVKRIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGALIHPCWVLTAAHCTDINTK 326
Query: 1895 PSSYKVILGAHEEHHLGEGVQEIDVSKLFK--------EPSGADIALLKLSSP----AVI 2038
KV+LG + Q V K+ K E DIALLKL A+
Sbjct: 327 --HLKVVLGDQDLKKTESHEQTFRVEKILKYSQYNERDEIPHNDIALLKLKPVGGHCALE 384
Query: 2039 TDQVIPACLPTPNYVVADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLDG 2218
+ V CLP+ + T C+I+GWG T+ G+ L +A++ +I N +CN + D
Sbjct: 385 SRYVKTVCLPSDPF--PSGTECHISGWGVTETGEGSRQLLDAKVKLIANPLCNSRQLYDH 442
Query: 2219 KVSSKELCAGHLAG-GIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRV 2395
+ +CAG+L G D+CQGDSGGPL C + Y + G+ SWG C KPGVY +V
Sbjct: 443 TIDDSMICAGNLQKPGSDTCQGDSGGPLTCEKDGTYYVYGIVSWGQECG--KKPGVYTQV 500
Query: 2396 SRFVTWIEEIMRR 2434
++F+ WI+ M R
Sbjct: 501 TKFLNWIKTTMHR 513
Score = 67.8 bits (164), Expect = 6e-11
Identities = 49/165 (29%), Positives = 67/165 (40%), Gaps = 5/165 (3%)
Frame = +2
Query: 650 PHAHGYLPSKFPNKNLKMNYCRNPDGEPRPWCFTTDPNKRWEFCDIPRCTTPPPTSGPTY 829
P LP+ PN C R C D K +FC+I GP
Sbjct: 102 PDCSKVLPACRPNPCQNGGVCSRHRRRSRFTCACPDQYKG-KFCEI----------GPD- 149
Query: 830 QCLKGRGENYRGTVSVTASGHTCQRWSAQS--PHKHNRTPENFPCKNL-EENYCRNPDGE 1000
C G G +YRG VS T + + C W++ +N E+ + E N+CRNPDG+
Sbjct: 150 DCYVGDGYSYRGKVSKTVNQNPCLYWNSHLLLQETYNMFMEDAETHGIAEHNFCRNPDGD 209
Query: 1001 TAPWCY--TTDSEVRWDYCKIPSCGSSTTSTEHLDAPVPPEQTPV 1129
PWC+ +V+W+YC + C PVP PV
Sbjct: 210 HKPWCFVKVNSEKVKWEYCDVTVC------------PVPDTPNPV 242
Score = 65.5 bits (158), Expect = 3e-10
Identities = 41/128 (32%), Positives = 58/128 (45%), Gaps = 14/128 (10%)
Frame = +2
Query: 464 CRNPDNDEKGPWCYTTDPETRFDYCDIPE------CE---DECMHCSGEHYEGKISKTMS 616
CR P+ + G C +RF C P+ CE D+C G Y GK+SKT++
Sbjct: 111 CR-PNPCQNGGVCSRHRRRSRFT-CACPDQYKGKFCEIGPDDCYVGDGYSYRGKVSKTVN 168
Query: 617 GIECQSWGSQSPHAHGY---LPSKFPNKNLKMNYCRNPDGEPRPWCF--TTDPNKRWEFC 781
C W S Y + + + N+CRNPDG+ +PWCF +WE+C
Sbjct: 169 QNPCLYWNSHLLLQETYNMFMEDAETHGIAEHNFCRNPDGDHKPWCFVKVNSEKVKWEYC 228
Query: 782 DIPRCTTP 805
D+ C P
Sbjct: 229 DVTVCPVP 236
Score = 64.7 bits (156), Expect = 5e-10
Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 5/84 (5%)
Frame = +2
Query: 1136 DCYRGNGESYRGTSSTTITGRKCQSWVS--MTPHRHEKTPGNFPNAGLTM-NYCRNPDAD 1306
DCY G+G SYRG S T+ C W S + + + G+ N+CRNPD D
Sbjct: 150 DCYVGDGYSYRGKVSKTVNQNPCLYWNSHLLLQETYNMFMEDAETHGIAEHNFCRNPDGD 209
Query: 1307 KSPWCY--TTDPRVRWEYCNLKKC 1372
PWC+ +V+WEYC++ C
Sbjct: 210 HKPWCFVKVNSEKVKWEYCDVTVC 233
Score = 54.7 bits (130), Expect = 5e-07
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 5/85 (5%)
Frame = +2
Query: 314 ECKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYS--PEKFPLAGL-EENYCRNPDND 484
+C G+G +YRG SKT + C W+ Y+ E G+ E N+CRNPD D
Sbjct: 150 DCYVGDGYSYRGKVSKTVNQNPCLYWNSHLLLQETYNMFMEDAETHGIAEHNFCRNPDGD 209
Query: 485 EKGPWCY--TTDPETRFDYCDIPEC 553
K PWC+ + +++YCD+ C
Sbjct: 210 HK-PWCFVKVNSEKVKWEYCDVTVC 233
>ref|NP_067464.1| coagulation factor XII (Hageman factor) [Mus musculus]
Length = 597
Score = 201 bits (511), Expect = 3e-51
Identities = 177/611 (28%), Positives = 251/611 (41%), Gaps = 92/611 (15%)
Frame = +2
Query: 866 TVSVTASGHTCQ---RWSAQSPHK--HNRTPENFPCKNLEENYCRNPDGETAPWCYTT-- 1024
TV +T G C ++ Q HK H R P + PWC TT
Sbjct: 37 TVVLTVDGRLCHFPFQYHRQLHHKCIHKRRPGS------------------RPWCATTPN 78
Query: 1025 -DSEVRWDYCKIPSCGSSTTSTEHLDAPVPPEQTPVAQDCYRGNGESYRGTSSTT----- 1186
D +W YC P V C + N GT T
Sbjct: 79 FDENQQWGYCLEPK--------------------KVKDHCSKHNPCHKGGTCINTPNGPH 118
Query: 1187 ------ITGRKCQSWVSMTP------HRHEKTPGNFPNAGLTMNYCRNPDADKSPWCYTT 1330
+TG+ CQ P H +E P G+ C+ +A P
Sbjct: 119 CLCPEHLTGKHCQKEKCFEPQLLKFFHENELWFKTGPG-GVARCECKGSEAHCKP----- 172
Query: 1331 DPRVRWEYCNLKKCSETEQ--QVTNFPAIAQVPSVE-------DLSEDCMFGNGKRYRGK 1483
V + C++ C V + P + + P+ DL C G G YRG+
Sbjct: 173 ---VASQACSINPCLNGGSCLLVEDHP-LCRCPTGYTGYFCDLDLWATCYEGRGLSYRGQ 228
Query: 1484 RATTVAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKN-YCRNPDGDDNGPWCYTTNPQKL 1660
TT +G PCQ W + +R+ T + GL + +CRNPD D PWC+ + +L
Sbjct: 229 AGTTQSGAPCQRWTVEATYRN--MTEKQALSWGLGHHAFCRNPDNDTR-PWCFVWSGDRL 285
Query: 1661 -FDYCDIPQCVTSSF---------------------------------------DCGKPK 1720
+DYC + QC T +F CG+
Sbjct: 286 SWDYCGLEQCQTPTFAPLVVPESQEESPSQAPSLSHAPNDSTDHQTSLSKTNTMGCGQRF 345
Query: 1721 VEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLTAKHCLEKSSSPS 1900
+ RVVGG V++P S P+ +L + +FC G+LI+P WVLTA HCL+ +P
Sbjct: 346 RKGLSSFMRVVGGLVALPGSHPYIAALYWG--NNFCAGSLIAPCWVLTAAHCLQNRPAPE 403
Query: 1901 SYKVILGAHEEHHLGEGVQEIDVS--KLFKEPSGA----DIALLKL-----SSPAVITDQ 2047
V+LG + E Q + V +L + S D+ALL+L +S A+++
Sbjct: 404 ELTVVLGQDRHNQSCEWCQTLAVRSYRLHEGFSSITYQHDLALLRLQESKTNSCAILSPH 463
Query: 2048 VIPACLPTPNYVVADRTACYITGWG---ETKGTYGAGLLKEARLPVIENKVCNRYEYLDG 2218
V P CLP+ ++ C + GWG E Y L+EA++P I C+
Sbjct: 464 VQPVCLPSGAAPPSETVLCEVAGWGHQLEGAEEYST-FLQEAQVPFIALDRCSNSNVHGD 522
Query: 2219 KVSSKELCAGHLAGGIDSCQGDSGGPLVCFE---KDKYILQGVTSWGLGCALPNKPGVYV 2389
+ LCAG L GG D+CQGDSGGPLVC E + + L+GV SWG GC NKPGVY
Sbjct: 523 AILPGMLCAGFLEGGTDACQGDSGGPLVCEEGTAEHQLTLRGVISWGSGCGDRNKPGVYT 582
Query: 2390 RVSRFVTWIEE 2422
V+ ++ WI++
Sbjct: 583 DVANYLAWIQK 593
Score = 83.2 bits (204), Expect = 1e-15
Identities = 83/303 (27%), Positives = 116/303 (38%), Gaps = 55/303 (18%)
Frame = +2
Query: 734 RPWCFTT---DPNKRWEFCDIPR-----CTTPPPTSGPTYQCLKGRGENYRGTVSVTASG 889
RPWC TT D N++W +C P+ C+ P C KG GT T +G
Sbjct: 70 RPWCATTPNFDENQQWGYCLEPKKVKDHCSKHNP-------CHKG------GTCINTPNG 116
Query: 890 HTCQRWSAQSPHKHNRTPENFPCKNLEENYCRNPD-----GETAPW----------CYTT 1024
C PE+ K+ ++ C P E W C
Sbjct: 117 PHCL------------CPEHLTGKHCQKEKCFEPQLLKFFHENELWFKTGPGGVARCECK 164
Query: 1025 DSE-----VRWDYCKIPSC---GSSTTSTEHLDAPVPPEQTPVAQD------CYRGNGES 1162
SE V C I C GS +H P T D CY G G S
Sbjct: 165 GSEAHCKPVASQACSINPCLNGGSCLLVEDHPLCRCPTGYTGYFCDLDLWATCYEGRGLS 224
Query: 1163 YRGTSSTTITGRKCQSWVSMTPHRHEKTPGNFPNAGLTMN-YCRNPDADKSPWCYT-TDP 1336
YRG + TT +G CQ W +R+ T + GL + +CRNPD D PWC+ +
Sbjct: 225 YRGQAGTTQSGAPCQRWTVEATYRN-MTEKQALSWGLGHHAFCRNPDNDTRPWCFVWSGD 283
Query: 1337 RVRWEYCNLKKC-----------SETEQQVTNFPAIAQVPS-----VEDLSEDCMFGNGK 1468
R+ W+YC L++C E+ + P+++ P+ LS+ G G+
Sbjct: 284 RLSWDYCGLEQCQTPTFAPLVVPESQEESPSQAPSLSHAPNDSTDHQTSLSKTNTMGCGQ 343
Query: 1469 RYR 1477
R+R
Sbjct: 344 RFR 346
Score = 62.0 bits (149), Expect = 3e-09
Identities = 32/83 (38%), Positives = 49/83 (59%), Gaps = 3/83 (3%)
Frame = +2
Query: 317 CKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKYSPEKFPLA-GLEEN-YCRNPDNDEK 490
C G G +YRG T+SG CQ+W+V + + + EK L+ GL + +CRNPDND +
Sbjct: 217 CYEGRGLSYRGQAGTTQSGAPCQRWTVEATY--RNMTEKQALSWGLGHHAFCRNPDNDTR 274
Query: 491 GPWCYT-TDPETRFDYCDIPECE 556
PWC+ + +DYC + +C+
Sbjct: 275 -PWCFVWSGDRLSWDYCGLEQCQ 296
Score = 57.4 bits (137), Expect = 8e-08
Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 1/108 (0%)
Frame = +2
Query: 485 EKGPWCYTTDPETRFDYCDIPECEDECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHG 664
E P C T + +CD+ + C G Y G+ T SG CQ W ++ + +
Sbjct: 193 EDHPLCRCPTGYTGY-FCDL-DLWATCYEGRGLSYRGQAGTTQSGAPCQRWTVEATYRNM 250
Query: 665 YLPSKFPNKNLKMNYCRNPDGEPRPWCFTTDPNK-RWEFCDIPRCTTP 805
+CRNPD + RPWCF ++ W++C + +C TP
Sbjct: 251 TEKQALSWGLGHHAFCRNPDNDTRPWCFVWSGDRLSWDYCGLEQCQTP 298
>ref|NP_032307.1| hepsin [Mus musculus]
Length = 416
Score = 199 bits (506), Expect = 1e-50
Identities = 126/330 (38%), Positives = 171/330 (51%), Gaps = 23/330 (6%)
Frame = +2
Query: 1496 VAGVPCQEWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDDNGPWCYTTNPQKLFDYCD 1675
VAG+ C+E HS T G +C + G Q+L D
Sbjct: 84 VAGLGCEEMGFLRALAHSELDVRTAGANGTSGFFCVDEGG--------LPLAQRLLDVIS 135
Query: 1676 IPQCVTSSF------DCGKPKVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGHFCGGT 1837
+ C F DCG+ K+ R+VGG S WPWQVSLRY H CGG+
Sbjct: 136 VCDCPRGRFLTATCQDCGRRKLPVD----RIVGGQDSSLGRWPWQVSLRYDGT-HLCGGS 190
Query: 1838 LISPEWVLTAKHCL-EKSSSPSSYKVILGA---HEEHHLGEGVQEIDVSK---LFKEPS- 1993
L+S +WVLTA HC E++ S ++V GA H + GVQ + F++P+
Sbjct: 191 LLSGDWVLTAAHCFPERNRVLSRWRVFAGAVARTSPHAVQLGVQAVIYHGGYLPFRDPTI 250
Query: 1994 ---GADIALLKLSSPAVITDQVIPACLPTPNYVVADRTACYITGWGETKGTYG--AGLLK 2158
DIAL+ LSS +T+ + P CLP + D C +TGWG T+ YG A +L+
Sbjct: 251 DENSNDIALVHLSSSLPLTEYIQPVCLPAAGQALVDGKVCTVTGWGNTQ-FYGQQAMVLQ 309
Query: 2159 EARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEK----DKYI 2326
EAR+P+I N+VCN ++ ++ K CAG+ GGID+CQGDSGGP VC + ++
Sbjct: 310 EARVPIISNEVCNSPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISGTSRWR 369
Query: 2327 LQGVTSWGLGCALPNKPGVYVRVSRFVTWI 2416
L G+ SWG GCAL KPGVY +V+ F WI
Sbjct: 370 LCGIVSWGTGCALARKPGVYTKVTDFREWI 399
>ref|NP_542765.1| transmembrane protease, serine 3 [Mus musculus]
Length = 453
Score = 197 bits (502), Expect = 4e-50
Identities = 104/238 (43%), Positives = 144/238 (60%), Gaps = 7/238 (2%)
Frame = +2
Query: 1745 RVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILG- 1921
R+VGG +S WPWQVSL+++ H CGG++I+P W++TA HC+ P S+ V +G
Sbjct: 216 RIVGGNMSSLTQWPWQVSLQFQGY-HLCGGSIITPLWIVTAAHCVYDLYHPKSWTVQVGL 274
Query: 1922 -----AHEEHHLGEGVQEIDVSKLFKEPSGADIALLKLSSPAVITDQVIPACLPTPNYVV 2086
+ HL E + I SK + G DIAL+KLS P + + P CLP
Sbjct: 275 VSLMDSPVPSHLVEKI--IYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPNSEENF 332
Query: 2087 ADRTACYITGWGETK-GTYGAGLLKEARLPVIENKVCNRYEYLDGKVSSKELCAGHLAGG 2263
D C+ +GWG T+ G + +L A +P+I NK+CN + G +S LCAG+L GG
Sbjct: 333 PDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLKGG 392
Query: 2264 IDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEEIMRRN 2437
+DSCQGDSGGPLVC E+ + L G TS+G+GCA NKPGVY R++ F+ WI E + R+
Sbjct: 393 VDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERD 450
>ref|NP_038949.2| transmembrane protease, serine 8 (intestinal) [Mus musculus]
Length = 310
Score = 192 bits (489), Expect = 1e-48
Identities = 102/248 (41%), Positives = 142/248 (57%), Gaps = 14/248 (5%)
Frame = +2
Query: 1745 RVVGGCVSIPHSWPWQVSLRYRYRGHFCGGTLISPEWVLTAKHCLEKSSSPSSYKVILGA 1924
++VGG ++ WPWQVSL GH CGG+LI WVLTA HC +S +PS Y V +G
Sbjct: 36 KIVGGQDALEGQWPWQVSLWITEDGHICGGSLIHEVWVLTAAHCFRRSLNPSFYHVKVGG 95
Query: 1925 H-----EEHHLGEGVQEIDV--SKLFKEPSGADIALLKLSSPAVITDQVIPACLPTPNYV 2083
E H V+ I V + L+ + S DIAL++L +P + Q P CLP
Sbjct: 96 LTLSLLEPHSTLVAVRNIFVHPTYLWADASSGDIALVQLDTP-LRPSQFTPVCLPAAQTP 154
Query: 2084 VADRTACYITGWGETKGTYGAGLLKEARLPVIENKVCNRYEYLDGK-------VSSKELC 2242
+ T C++TGWG T+ A +L+E +P+++++ C + + G + S LC
Sbjct: 155 LTPGTVCWVTGWGATQERDMASVLQELAVPLLDSEDCEKMYHTQGSSLSGERIIQSDMLC 214
Query: 2243 AGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVRVSRFVTWIEE 2422
AG++ G DSCQGDSGGPLVC + G+TSWG+GCA P +PGVY RV +V WI+
Sbjct: 215 AGYVEGQKDSCQGDSGGPLVCSINSSWTQVGITSWGIGCARPYRPGVYTRVPTYVDWIQR 274
Query: 2423 IMRRN*SD 2446
I+ N SD
Sbjct: 275 ILAENHSD 282
>ref|NP_062320.1| hepatocyte growth factor activator [Mus musculus]
Length = 653
Score = 188 bits (477), Expect = 3e-47
Identities = 124/373 (33%), Positives = 172/373 (46%), Gaps = 42/373 (11%)
Frame = +2
Query: 1439 SEDCMFGNGKRYRGKRATTVAGVPCQEWAA----QEPHRHSIFTPETNPRAGLEKN-YCR 1603
+E C GNG YRG +T +G+ C W + QE H S+ GL + YCR
Sbjct: 280 TEHCFLGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVAAAVL---LGLGPHAYCR 336
Query: 1604 NPDGDDNGPWCYTTNPQKL-FDYCDIPQCVTSSF---------------------DCGKP 1717
NPD D+ PWCY L ++YC + C + + CGK
Sbjct: 337 NPDKDER-PWCYVVKDNALSWEYCRLTACESLARVHSQTPEILAALPESAPAVRPTCGKR 395
Query: 1718 KVEPKKCPARVVGGCVSIPHSWPWQVSLRYRYRGH-FCGGTLISPEWVLTAKHCLEKSSS 1894
+ R++GG S+P S PW ++ Y G+ FC G+L+ WV++A HC S
Sbjct: 396 HKKRTFLRPRIIGGSSSLPGSHPWLAAI---YIGNSFCAGSLVHTCWVVSAAHCFANSPP 452
Query: 1895 PSSYKVILGAHEEHHLGEGVQEIDVSKLFK-------EPSGADIALLKLSSP----AVIT 2041
S V+LG H + + Q + K P+ D+ L++L AV +
Sbjct: 453 RDSITVVLGQHFFNRTTDVTQTFGIEKYVPYTLYSVFNPNNHDLVLIRLKKKGERCAVRS 512
Query: 2042 DQVIPACLPTPNYVVADRTACYITGWG---ETKGTYGAGLLKEARLPVIENKVCNRYEYL 2212
V P CLP C I GWG E +Y LL EA +P++ + C+ E
Sbjct: 513 QFVQPICLPEAGSSFPTGHKCQIAGWGHMDENVSSYSNSLL-EALVPLVADHKCSSPEVY 571
Query: 2213 DGKVSSKELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCALPNKPGVYVR 2392
+S LCAG+ D+CQGDSGGPLVC + L G+ SWG GC NKPGVY R
Sbjct: 572 GADISPNMLCAGYFDCKSDACQGDSGGPLVCEKNGVAYLYGIISWGDGCGRLNKPGVYTR 631
Query: 2393 VSRFVTWIEEIMR 2431
V+ +V WI + +R
Sbjct: 632 VANYVDWINDRIR 644
Score = 71.6 bits (174), Expect = 4e-12
Identities = 71/289 (24%), Positives = 108/289 (37%), Gaps = 42/289 (14%)
Frame = +2
Query: 671 PSKFPNK--NLKMNYCRNPDGEPRPWCFTT---DPNKRWEFCD-----------IPRCTT 802
P +FP + ++ C + R WC TT D ++ W +C + C +
Sbjct: 104 PCRFPFRYGGRMLHSCTSEGSAYRKWCATTHNYDRDRAWGYCAEVTLPVEGPAILDPCAS 163
Query: 803 PPPTSGPTYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFPCKNLEENYC 982
P +G T G +Y + + +G C ++ E F + +++
Sbjct: 164 WPCLNGGTCSSTHDHG-SYHCSCPLAFTGKDCGTEKCFDETRY----EYF---EVGDHWA 215
Query: 983 RNPDGETAPWCYTTDSEVRWDYCKIPSCGSST------------TSTEHLDAP------- 1105
R +G C + + R + +C SS T T P
Sbjct: 216 RVSEGHVEQ-CGCMEGQARCEDTHHTACLSSPCLNGGTCHLIVGTGTSVCTCPLGYAGRF 274
Query: 1106 ---VPPEQTPVAQDCYRGNGESYRGTSSTTITGRKCQSWVS--MTPHRHEKTPGNFPNAG 1270
VP E C+ GNG YRG +ST +G C +W S + H + G
Sbjct: 275 CNIVPTEH------CFLGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVAAAVLLG 328
Query: 1271 LTMN-YCRNPDADKSPWCYTT-DPRVRWEYCNLKKCSETEQQVTNFPAI 1411
L + YCRNPD D+ PWCY D + WEYC L C + + P I
Sbjct: 329 LGPHAYCRNPDKDERPWCYVVKDNALSWEYCRLTACESLARVHSQTPEI 377
Score = 69.3 bits (168), Expect = 2e-11
Identities = 40/129 (31%), Positives = 56/129 (43%), Gaps = 13/129 (10%)
Frame = +2
Query: 794 CTTPPPTSG------PTYQCLKGRGENYRGTVSVTASGHTCQRWSAQSPHKHNRTPENFP 955
CT P +G PT C G G YRG S ASG +C W++ ++
Sbjct: 264 CTCPLGYAGRFCNIVPTEHCFLGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVAA 323
Query: 956 CKNL---EENYCRNPDGETAPWCYTT-DSEVRWDYCKIPSCGSST---TSTEHLDAPVPP 1114
L YCRNPD + PWCY D+ + W+YC++ +C S + T + A +P
Sbjct: 324 AVLLGLGPHAYCRNPDKDERPWCYVVKDNALSWEYCRLTACESLARVHSQTPEILAALPE 383
Query: 1115 EQTPVAQDC 1141
V C
Sbjct: 384 SAPAVRPTC 392
Score = 57.4 bits (137), Expect = 8e-08
Identities = 33/84 (39%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Frame = +2
Query: 317 CKTGNGKNYRGTTSKTKSGVICQKWSVSSPHIPKY--SPEKFPLAGLEEN-YCRNPDNDE 487
C GNG YRG S SG+ C W+ + + S L GL + YCRNPD DE
Sbjct: 283 CFLGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVAAAVLLGLGPHAYCRNPDKDE 342
Query: 488 KGPWCYTT-DPETRFDYCDIPECE 556
+ PWCY D ++YC + CE
Sbjct: 343 R-PWCYVVKDNALSWEYCRLTACE 365
Score = 57.4 bits (137), Expect = 8e-08
Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Frame = +2
Query: 533 YCDIPECEDECMHCSGEHYEGKISKTMSGIECQSWGSQSPHAHGYLPSKFPNKNLKMN-- 706
+C+I E C +G Y G S SG+ C +W S + ++ S L +
Sbjct: 274 FCNIVPTE-HCFLGNGTEYRGVASTAASGLSCLAWNSDLLYQELHVDSVAAAVLLGLGPH 332
Query: 707 -YCRNPDGEPRPWCFTTDPNK-RWEFCDIPRC 796
YCRNPD + RPWC+ N WE+C + C
Sbjct: 333 AYCRNPDKDERPWCYVVKDNALSWEYCRLTAC 364
Database: RefSeqMP
Posted date: Aug 2, 2006 12:58 AM
Number of letters in database: 21,768,885
Number of sequences in database: 45,328
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 144,358,265
Number of Sequences: 45328
Number of extensions: 4369872
Number of successful extensions: 17394
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 11067
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 16419
length of database: 21,768,885
effective HSP length: 113
effective length of database: 16,646,821
effective search space used: 13117694948
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)