Search to RefSeqBP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= OVR01_0046_B07
(1498 letters)
Database: RefSeqBP
33,508 sequences; 16,112,626 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|XP_873755.1| PREDICTED: similar to WD repeat domain 5, parti... 261 1e-69
Alignment gi|NP_777088.1| platelet-activating factor acetylhydrolase, iso... 187 2e-47
Alignment gi|XP_608583.2| PREDICTED: similar to CG7568-PA [Bos taurus] 184 2e-46
Alignment gi|XP_871162.1| PREDICTED: similar to WD repeat domain 5, parti... 179 4e-45
Alignment gi|XP_614481.2| PREDICTED: similar to WD-repeat protein 57 isof... 169 4e-42
Alignment gi|XP_883815.1| PREDICTED: similar to F-box protein FBW7 isofor... 169 4e-42
Alignment gi|XP_883785.1| PREDICTED: similar to F-box protein FBW7 isofor... 169 4e-42
Alignment gi|XP_883749.1| PREDICTED: similar to F-box protein FBW7 isofor... 169 4e-42
Alignment gi|XP_613742.2| PREDICTED: similar to F-box protein FBW7 isofor... 169 4e-42
Alignment gi|XP_883690.1| PREDICTED: similar to F-box protein FBW7 isofor... 169 4e-42
>ref|XP_873755.1| PREDICTED: similar to WD repeat domain 5, partial [Bos taurus]
Length = 123
Score = 261 bits (667), Expect = 1e-69
Identities = 123/123 (100%), Positives = 123/123 (100%)
Frame = +1
Query: 835 DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG 1014
DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG
Sbjct: 1 DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG 60
Query: 1015 KWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 1194
KWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK
Sbjct: 61 KWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 120
Query: 1195 SDC 1203
SDC
Sbjct: 121 SDC 123
Score = 72.0 bits (175), Expect = 1e-12
Identities = 41/114 (35%), Positives = 66/114 (57%), Gaps = 5/114 (4%)
Frame = +1
Query: 469 ISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFC--CNFN-PQSNLIVS 639
+S V +S + +++A+ D TLK+WD S GKCLKT GH N +C NF+ IVS
Sbjct: 6 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVS 65
Query: 640 GSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSY--DGLCRIW 795
GS D V IW+++T + ++ L H+D V + + ++I S++ D ++W
Sbjct: 66 GSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 119
Score = 69.7 bits (169), Expect = 6e-12
Identities = 36/120 (30%), Positives = 67/120 (55%), Gaps = 11/120 (9%)
Frame = +1
Query: 343 VSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHK---------LGISDVAWSSD 495
VS VKFSPNG+++ +++ D +K+W GK KT +GHK ++ W
Sbjct: 6 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKW--- 62
Query: 496 SNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSF--DESVRIW 669
+VS S+D + IW++ + + ++ L+GH++ V +P N+I S + D+++++W
Sbjct: 63 ---IVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 119
>ref|NP_777088.1| platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit
(45kD) [Bos taurus]
Length = 410
Score = 187 bits (474), Expect = 2e-47
Identities = 100/313 (31%), Positives = 165/313 (52%), Gaps = 19/313 (6%)
Frame = +1
Query: 313 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS 492
K+ L+GH V+ V F P + S+S D IK+W G FE+T+ GH + D+++
Sbjct: 101 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVEDISFDH 160
Query: 493 DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 672
LL S S D T+K+WD +C++T+ GH + V P + IVS S D+++++W+
Sbjct: 161 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
Query: 673 VKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDN--- 843
V+TG C+KT H + V V N+DG+LI S S D R+W A+ +C L + ++
Sbjct: 221 VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 280
Query: 844 -----PPVSFVKFS-----------PNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNE 975
P S+ S G ++L+ + D T+K+WD S G CL T GH N
Sbjct: 281 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 340
Query: 976 KYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIAS 1155
+ + +GGK+I+S ++D + +W+ + K ++ L H V S H T + +
Sbjct: 341 VRGVLFH---SGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 397
Query: 1156 AALENDKTIKLWK 1194
++ D+T+K+W+
Sbjct: 398 GSV--DQTVKVWE 408
Score = 84.7 bits (208), Expect = 2e-16
Identities = 36/103 (34%), Positives = 62/103 (60%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV 549
G +L S S DK IK+W G T+ GH + V + S ++S +DDKTL++WD
Sbjct: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
Query: 550 SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 678
+ +C+KTL H ++V +F+ + +V+GS D++V++W+ +
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
>ref|XP_608583.2| PREDICTED: similar to CG7568-PA [Bos taurus]
Length = 441
Score = 184 bits (467), Expect = 2e-46
Identities = 101/293 (34%), Positives = 161/293 (54%), Gaps = 1/293 (0%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFS-PNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD 495
TL GH V ++ F+ P G+ +A+ S DK K+W GK T GH I ++++
Sbjct: 155 TLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQ 214
Query: 496 SNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 675
S L+ + S D T K+WD+ SG+ + TL GHS + +FN N I++GSFD +V +W+
Sbjct: 215 STLVATGSMDTTAKLWDIQSGEEVFTLTGHSAEIISLSFNTSGNRIITGSFDHTVTVWEA 274
Query: 676 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVS 855
TG+ + TL H +S+ FN D SLI++ S D C++WD +G+C+ TL D+ +
Sbjct: 275 DTGRKVYTLIGHCAEISSAVFNWDCSLILTGSMDKTCKLWDAVNGKCVATLTGHDDEILD 334
Query: 856 FVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGS 1035
F GK I A+ D T +++ + +C+ GH+ E I N G +++GS
Sbjct: 335 SC-FDYTGKLIATASADGTARIFSAATRECVTKLEGHEGEISKISFN---PQGNRLLTGS 390
Query: 1036 EDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 1194
D IW+ QT + +Q L+GHTD + S A + +II + + D T ++W+
Sbjct: 391 SDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGDIIITGS--KDNTCRIWR 441
Score = 176 bits (446), Expect = 4e-44
Identities = 93/291 (31%), Positives = 163/291 (56%), Gaps = 1/291 (0%)
Frame = +1
Query: 322 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD-S 498
L H +++V + +G + S D+ K+W G+ T+ GH+ + +A+++
Sbjct: 114 LRAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELHTLEGHRNVVYAIAFNNPYG 173
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 678
+ + + S DKT K+W V +GKC T +GH+ + C +FNPQS L+ +GS D + ++WD++
Sbjct: 174 DKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQ 233
Query: 679 TGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSF 858
+G+ + TL HS + ++ FN G+ I++ S+D +W+ +G+ + TLI +S
Sbjct: 234 SGEEVFTLTGHSAEIISLSFNTSGNRIITGSFDHTVTVWEADTGRKVYTLI-GHCAEISS 292
Query: 859 VKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE 1038
F+ + IL ++D T KLWD GKC+ T TGH +E + + F T GK I + S
Sbjct: 293 AVFNWDCSLILTGSMDKTCKLWDAVNGKCVATLTGHDDE--ILDSCFDYT-GKLIATASA 349
Query: 1039 DNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 1191
D I++ T+E V KL+GH + + +P N + + + +DKT ++W
Sbjct: 350 DGTARIFSAATRECVTKLEGHEGEISKISFNPQGNRLLTGS--SDKTARIW 398
Score = 135 bits (340), Expect = 8e-32
Identities = 67/203 (33%), Positives = 110/203 (54%)
Frame = +1
Query: 316 FTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD 495
FTL GH+ + S+ F+ +G + + S D + +W A G+ T+ GH IS ++ D
Sbjct: 239 FTLTGHSAEIISLSFNTSGNRIITGSFDHTVTVWEADTGRKVYTLIGHCAEISSAVFNWD 298
Query: 496 SNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 675
+L+++ S DKT K+WD +GKC+ TL GH + + F+ LI + S D + RI+
Sbjct: 299 CSLILTGSMDKTCKLWDAVNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSA 358
Query: 676 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVS 855
T +C+ L H +S + FN G+ +++ S D RIWD +GQCL+ L + +
Sbjct: 359 ATRECVTKLEGHEGEISKISFNPQGNRLLTGSSDKTARIWDAQTGQCLQVL-EGHTDEIF 417
Query: 856 FVKFSPNGKYILAATLDNTLKLW 924
F+ G I+ + DNT ++W
Sbjct: 418 SCAFNYKGDIIITGSKDNTCRIW 440
Score = 106 bits (265), Expect = 4e-23
Identities = 59/169 (34%), Positives = 89/169 (52%)
Frame = +1
Query: 694 KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSP 873
K L AH P++ V N+ GS ++ SYD C++WDTASG+ L TL N + +P
Sbjct: 112 KVLRAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELHTLEGHRNVVYAIAFNNP 171
Query: 874 NGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVY 1053
G I + D T KLW GKC T+ GH E C+ N T + +GS D
Sbjct: 172 YGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQST---LVATGSMDTTAK 228
Query: 1054 IWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSD 1200
+W++Q+ E V L GH+ +IS + + + N I + + D T+ +W++D
Sbjct: 229 LWDIQSGEEVFTLTGHSAEIISLSFNTSGNRIITGSF--DHTVTVWEAD 275
>ref|XP_871162.1| PREDICTED: similar to WD repeat domain 5, partial [Bos taurus]
Length = 440
Score = 179 bits (455), Expect = 4e-45
Identities = 88/88 (100%), Positives = 88/88 (100%)
Frame = +1
Query: 292 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI 471
VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI
Sbjct: 298 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI 357
Query: 472 SDVAWSSDSNLLVSASDDKTLKIWDVSS 555
SDVAWSSDSNLLVSASDDKTLKIWDVSS
Sbjct: 358 SDVAWSSDSNLLVSASDDKTLKIWDVSS 385
Score = 64.7 bits (156), Expect = 2e-10
Identities = 31/79 (39%), Positives = 48/79 (60%)
Frame = +1
Query: 445 TISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQS 624
T++GH +S V +S + L S+S DK +KIW GK KT+ GH + ++ S
Sbjct: 307 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 366
Query: 625 NLIVSGSFDESVRIWDVKT 681
NL+VS S D++++IWDV +
Sbjct: 367 NLLVSASDDKTLKIWDVSS 385
Score = 60.1 bits (144), Expect = 4e-09
Identities = 41/123 (33%), Positives = 58/123 (47%), Gaps = 15/123 (12%)
Frame = +1
Query: 484 WSSDSN----LLVSA----------SDDKTLKIWDVSSGKCLK-TLKGHSNYVFCCNFNP 618
WS D LL+SA + LK V LK TL GH+ V F+P
Sbjct: 263 WSRDEGHGGALLLSALLRRWDVWVTKQETPLKPTPVKPNYALKFTLAGHTKAVSSVKFSP 322
Query: 619 QSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD 798
+ S S D+ ++IW GK KT+ H +S V ++ D +L+VS+S D +IWD
Sbjct: 323 NGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWD 382
Query: 799 TAS 807
+S
Sbjct: 383 VSS 385
Score = 53.9 bits (128), Expect = 3e-07
Identities = 34/88 (38%), Positives = 49/88 (55%), Gaps = 1/88 (1%)
Frame = +1
Query: 673 VKTGKCLK-TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 849
VK LK TL H+ VS+V F+ +G + SSS D L +IW G+ KT I
Sbjct: 298 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKT-ISGHKLG 356
Query: 850 VSFVKFSPNGKYILAATLDNTLKLWDYS 933
+S V +S + +++A+ D TLK+WD S
Sbjct: 357 ISDVAWSSDSNLLVSASDDKTLKIWDVS 384
Score = 49.7 bits (117), Expect = 6e-06
Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 6/91 (6%)
Frame = +1
Query: 817 LKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFAN 996
LK + VS VKFSPNG+++ +++ D +K+W GK KT +GHK
Sbjct: 304 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHK--------- 354
Query: 997 FSVTGGKW------IVSGSEDNLVYIWNLQT 1071
++ W +VS S+D + IW++ +
Sbjct: 355 LGISDVAWSSDSNLLVSASDDKTLKIWDVSS 385
>ref|XP_614481.2| PREDICTED: similar to WD-repeat protein 57 isoform 1 [Bos taurus]
Length = 358
Score = 169 bits (429), Expect = 4e-42
Identities = 100/290 (34%), Positives = 160/290 (55%), Gaps = 10/290 (3%)
Frame = +1
Query: 322 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAY-DGKFEKTISGHKLGISDVAWSSDS 498
L+GH V KF PNG LAS+ D+LI +W Y D T+ GH + ++ +++D
Sbjct: 63 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 122
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCC---NFNPQSNLIVSGSFDESVRIW 669
++L SAS DKT+ +WD +G+ +K LKGH+++V C PQ L+ +GS D +V++W
Sbjct: 123 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQ--LVCTGSDDGTVKLW 180
Query: 670 DVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 849
D++ ++T ++ V AV FN I+S D ++WD + T+ +
Sbjct: 181 DIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADS- 238
Query: 850 VSFVKFSPNGKYILAATLDNTLKLWDYS----KGKCLKTYTG--HKNEKYCIFANFSVTG 1011
V+ + S G Y+L+ +DNT+++WD K +C+K + G H EK + ++S G
Sbjct: 239 VTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDG 298
Query: 1012 GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAA 1161
K I +GS D VY+W+ ++ I+ KL GH + A HP E II SA+
Sbjct: 299 SK-IAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIILSAS 347
Score = 109 bits (273), Expect = 5e-24
Identities = 61/208 (29%), Positives = 107/208 (51%), Gaps = 2/208 (0%)
Frame = +1
Query: 574 LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKC--LKTLPAHSDPVSAVHFNRD 747
L GH V+CC F+P + + S FD + +W+V G C TL HS V +H+N D
Sbjct: 63 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVY-GDCDNYATLKGHSGAVMELHYNTD 121
Query: 748 GSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWD 927
GS++ S+S D +WD+ +G+ +K L + S + + + D T+KLWD
Sbjct: 122 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 181
Query: 928 YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTD 1107
K ++T+ +N + F+ T + I+SG DN + +W+L+ ++ ++GH D
Sbjct: 182 IRKKAAIQTF---QNTYQVLAVTFNDTSDQ-IISGGIDNDIKVWDLRQNKLTYTMRGHAD 237
Query: 1108 VVISTACHPTENIIASAALENDKTIKLW 1191
V + + + S A++N T+++W
Sbjct: 238 SVTGLSLSSEGSYLLSNAMDN--TVRVW 263
Score = 84.3 bits (207), Expect = 2e-16
Identities = 45/157 (28%), Positives = 83/157 (52%), Gaps = 8/157 (5%)
Frame = +1
Query: 331 HTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLV 510
+T V +V F+ + + S D IK+W K T+ GH ++ ++ SS+ + L+
Sbjct: 193 NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLL 252
Query: 511 SASDDKTLKIWDVS----SGKCLKTLKGH----SNYVFCCNFNPQSNLIVSGSFDESVRI 666
S + D T+++WDV +C+K +G+ + C+++P + I +GS D V +
Sbjct: 253 SNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYV 312
Query: 667 WDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYD 777
WD + + L LP H+ ++ V F+ D +I+S+S D
Sbjct: 313 WDTTSRRILYKLPGHAGSINEVAFHPDEPIILSASSD 349
Score = 62.4 bits (150), Expect = 9e-10
Identities = 30/131 (22%), Positives = 65/131 (49%), Gaps = 8/131 (6%)
Frame = +1
Query: 310 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGK--------FEKTISGHKL 465
L +T+ GH +V+ + S G +L S++ D +++W F+ + +
Sbjct: 228 LTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEK 287
Query: 466 GISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGS 645
+ +WS D + + + S D+ + +WD +S + L L GH+ + F+P +I+S S
Sbjct: 288 NLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIILSAS 347
Query: 646 FDESVRIWDVK 678
D+ + + +++
Sbjct: 348 SDKRLYMGEIQ 358
>ref|XP_883815.1| PREDICTED: similar to F-box protein FBW7 isoform 1 isoform 6 [Bos
taurus]
Length = 706
Score = 169 bits (429), Expect = 4e-42
Identities = 98/284 (34%), Positives = 162/284 (57%), Gaps = 10/284 (3%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIW 543
G + S S D +K+W A GK +T+ GH G+ WSS N+++S S D+TLK+W
Sbjct: 390 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVW 445
Query: 544 DVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPV 723
+ +G+C+ TL GH++ V C + + + +VSGS D ++R+WD++TG+CL L H V
Sbjct: 446 NAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAV 503
Query: 724 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATL 903
V + DG +VS +YD + ++WD + CL TL N S ++F +G ++++ +L
Sbjct: 504 RCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYS-LQF--DGIHVVSGSL 558
Query: 904 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG-----KWIVSGSEDNLVYIWNLQ 1068
D ++++WD G C+ T TGH+ S+T G +VSG+ D+ V IW+++
Sbjct: 559 DTSIRVWDVETGNCIHTLTGHQ----------SLTSGMELKDNILVSGNADSTVKIWDIK 608
Query: 1069 TKEIVQKLQG---HTDVVISTACHPTENIIASAALENDKTIKLW 1191
T + +Q LQG H V T +N + +++ +D T+KLW
Sbjct: 609 TGQCLQTLQGPNKHQSAV--TCLQFNKNFVITSS--DDGTVKLW 648
Score = 92.4 bits (228), Expect = 8e-19
Identities = 50/131 (38%), Positives = 79/131 (60%), Gaps = 3/131 (2%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 498
TL GHT V S++F +G + S S D I++W G T++GH+ S +
Sbjct: 535 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD-- 590
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKG---HSNYVFCCNFNPQSNLIVSGSFDESVRIW 669
N+LVS + D T+KIWD+ +G+CL+TL+G H + V C FN N +++ S D +V++W
Sbjct: 591 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFN--KNFVITSSDDGTVKLW 648
Query: 670 DVKTGKCLKTL 702
D+KTG+ ++ L
Sbjct: 649 DLKTGEFIRNL 659
>ref|XP_883785.1| PREDICTED: similar to F-box protein FBW7 isoform 3 isoform 5 [Bos
taurus]
Length = 589
Score = 169 bits (429), Expect = 4e-42
Identities = 98/284 (34%), Positives = 162/284 (57%), Gaps = 10/284 (3%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIW 543
G + S S D +K+W A GK +T+ GH G+ WSS N+++S S D+TLK+W
Sbjct: 273 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVW 328
Query: 544 DVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPV 723
+ +G+C+ TL GH++ V C + + + +VSGS D ++R+WD++TG+CL L H V
Sbjct: 329 NAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAV 386
Query: 724 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATL 903
V + DG +VS +YD + ++WD + CL TL N S ++F +G ++++ +L
Sbjct: 387 RCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYS-LQF--DGIHVVSGSL 441
Query: 904 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG-----KWIVSGSEDNLVYIWNLQ 1068
D ++++WD G C+ T TGH+ S+T G +VSG+ D+ V IW+++
Sbjct: 442 DTSIRVWDVETGNCIHTLTGHQ----------SLTSGMELKDNILVSGNADSTVKIWDIK 491
Query: 1069 TKEIVQKLQG---HTDVVISTACHPTENIIASAALENDKTIKLW 1191
T + +Q LQG H V T +N + +++ +D T+KLW
Sbjct: 492 TGQCLQTLQGPNKHQSAV--TCLQFNKNFVITSS--DDGTVKLW 531
Score = 92.4 bits (228), Expect = 8e-19
Identities = 50/131 (38%), Positives = 79/131 (60%), Gaps = 3/131 (2%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 498
TL GHT V S++F +G + S S D I++W G T++GH+ S +
Sbjct: 418 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD-- 473
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKG---HSNYVFCCNFNPQSNLIVSGSFDESVRIW 669
N+LVS + D T+KIWD+ +G+CL+TL+G H + V C FN N +++ S D +V++W
Sbjct: 474 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFN--KNFVITSSDDGTVKLW 531
Query: 670 DVKTGKCLKTL 702
D+KTG+ ++ L
Sbjct: 532 DLKTGEFIRNL 542
>ref|XP_883749.1| PREDICTED: similar to F-box protein FBW7 isoform 2 isoform 4 [Bos
taurus]
Length = 629
Score = 169 bits (429), Expect = 4e-42
Identities = 98/284 (34%), Positives = 162/284 (57%), Gaps = 10/284 (3%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIW 543
G + S S D +K+W A GK +T+ GH G+ WSS N+++S S D+TLK+W
Sbjct: 313 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVW 368
Query: 544 DVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPV 723
+ +G+C+ TL GH++ V C + + + +VSGS D ++R+WD++TG+CL L H V
Sbjct: 369 NAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAV 426
Query: 724 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATL 903
V + DG +VS +YD + ++WD + CL TL N S ++F +G ++++ +L
Sbjct: 427 RCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYS-LQF--DGIHVVSGSL 481
Query: 904 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG-----KWIVSGSEDNLVYIWNLQ 1068
D ++++WD G C+ T TGH+ S+T G +VSG+ D+ V IW+++
Sbjct: 482 DTSIRVWDVETGNCIHTLTGHQ----------SLTSGMELKDNILVSGNADSTVKIWDIK 531
Query: 1069 TKEIVQKLQG---HTDVVISTACHPTENIIASAALENDKTIKLW 1191
T + +Q LQG H V T +N + +++ +D T+KLW
Sbjct: 532 TGQCLQTLQGPNKHQSAV--TCLQFNKNFVITSS--DDGTVKLW 571
Score = 92.4 bits (228), Expect = 8e-19
Identities = 50/131 (38%), Positives = 79/131 (60%), Gaps = 3/131 (2%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 498
TL GHT V S++F +G + S S D I++W G T++GH+ S +
Sbjct: 458 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD-- 513
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKG---HSNYVFCCNFNPQSNLIVSGSFDESVRIW 669
N+LVS + D T+KIWD+ +G+CL+TL+G H + V C FN N +++ S D +V++W
Sbjct: 514 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFN--KNFVITSSDDGTVKLW 571
Query: 670 DVKTGKCLKTL 702
D+KTG+ ++ L
Sbjct: 572 DLKTGEFIRNL 582
>ref|XP_613742.2| PREDICTED: similar to F-box protein FBW7 isoform 1 isoform 1 [Bos
taurus]
Length = 706
Score = 169 bits (429), Expect = 4e-42
Identities = 98/284 (34%), Positives = 162/284 (57%), Gaps = 10/284 (3%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIW 543
G + S S D +K+W A GK +T+ GH G+ WSS N+++S S D+TLK+W
Sbjct: 390 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVW 445
Query: 544 DVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPV 723
+ +G+C+ TL GH++ V C + + + +VSGS D ++R+WD++TG+CL L H V
Sbjct: 446 NAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAV 503
Query: 724 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATL 903
V + DG +VS +YD + ++WD + CL TL N S ++F +G ++++ +L
Sbjct: 504 RCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYS-LQF--DGIHVVSGSL 558
Query: 904 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG-----KWIVSGSEDNLVYIWNLQ 1068
D ++++WD G C+ T TGH+ S+T G +VSG+ D+ V IW+++
Sbjct: 559 DTSIRVWDVETGNCIHTLTGHQ----------SLTSGMELKDNILVSGNADSTVKIWDIK 608
Query: 1069 TKEIVQKLQG---HTDVVISTACHPTENIIASAALENDKTIKLW 1191
T + +Q LQG H V T +N + +++ +D T+KLW
Sbjct: 609 TGQCLQTLQGPNKHQSAV--TCLQFNKNFVITSS--DDGTVKLW 648
Score = 92.4 bits (228), Expect = 8e-19
Identities = 50/131 (38%), Positives = 79/131 (60%), Gaps = 3/131 (2%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 498
TL GHT V S++F +G + S S D I++W G T++GH+ S +
Sbjct: 535 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD-- 590
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKG---HSNYVFCCNFNPQSNLIVSGSFDESVRIW 669
N+LVS + D T+KIWD+ +G+CL+TL+G H + V C FN N +++ S D +V++W
Sbjct: 591 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFN--KNFVITSSDDGTVKLW 648
Query: 670 DVKTGKCLKTL 702
D+KTG+ ++ L
Sbjct: 649 DLKTGEFIRNL 659
>ref|XP_883690.1| PREDICTED: similar to F-box protein FBW7 isoform 2 isoform 3 [Bos
taurus]
Length = 627
Score = 169 bits (429), Expect = 4e-42
Identities = 98/284 (34%), Positives = 162/284 (57%), Gaps = 10/284 (3%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIW 543
G + S S D +K+W A GK +T+ GH G+ WSS N+++S S D+TLK+W
Sbjct: 311 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVW 366
Query: 544 DVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPV 723
+ +G+C+ TL GH++ V C + + + +VSGS D ++R+WD++TG+CL L H V
Sbjct: 367 NAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAV 424
Query: 724 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATL 903
V + DG +VS +YD + ++WD + CL TL N S ++F +G ++++ +L
Sbjct: 425 RCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYS-LQF--DGIHVVSGSL 479
Query: 904 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG-----KWIVSGSEDNLVYIWNLQ 1068
D ++++WD G C+ T TGH+ S+T G +VSG+ D+ V IW+++
Sbjct: 480 DTSIRVWDVETGNCIHTLTGHQ----------SLTSGMELKDNILVSGNADSTVKIWDIK 529
Query: 1069 TKEIVQKLQG---HTDVVISTACHPTENIIASAALENDKTIKLW 1191
T + +Q LQG H V T +N + +++ +D T+KLW
Sbjct: 530 TGQCLQTLQGPNKHQSAV--TCLQFNKNFVITSS--DDGTVKLW 569
Score = 92.4 bits (228), Expect = 8e-19
Identities = 50/131 (38%), Positives = 79/131 (60%), Gaps = 3/131 (2%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 498
TL GHT V S++F +G + S S D I++W G T++GH+ S +
Sbjct: 456 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD-- 511
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKG---HSNYVFCCNFNPQSNLIVSGSFDESVRIW 669
N+LVS + D T+KIWD+ +G+CL+TL+G H + V C FN N +++ S D +V++W
Sbjct: 512 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFN--KNFVITSSDDGTVKLW 569
Query: 670 DVKTGKCLKTL 702
D+KTG+ ++ L
Sbjct: 570 DLKTGEFIRNL 580
Database: RefSeqBP
Posted date: Aug 1, 2006 7:14 PM
Number of letters in database: 16,112,626
Number of sequences in database: 33,508
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,959,656
Number of Sequences: 33508
Number of extensions: 1111708
Number of successful extensions: 9334
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 4245
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6596
length of database: 16,112,626
effective HSP length: 106
effective length of database: 12,560,778
effective search space used: 4923824976
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqCP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= OVR01_0046_B07
(1498 letters)
Database: RefSeqCP
33,732 sequences; 19,266,565 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|XP_850117.1| PREDICTED: similar to WD repeat domain 5 [Canis... 607 e-174
Alignment gi|XP_537775.2| PREDICTED: similar to platelet-activating facto... 187 3e-47
Alignment gi|XP_854482.1| PREDICTED: similar to platelet-activating facto... 187 3e-47
Alignment gi|XP_868508.1| PREDICTED: similar to platelet-activating facto... 187 3e-47
Alignment gi|XP_868519.1| PREDICTED: similar to platelet-activating facto... 185 1e-46
Alignment gi|XP_534593.2| PREDICTED: similar to CG7568-PA [Canis familiaris] 185 1e-46
Alignment gi|XP_532689.2| PREDICTED: similar to F-box protein FBW7 isofor... 169 5e-42
Alignment gi|XP_867720.1| PREDICTED: similar to F-box protein FBW7 isofor... 169 5e-42
Alignment gi|XP_853624.1| PREDICTED: similar to F-box protein FBW7 isofor... 169 5e-42
Alignment gi|XP_854730.1| PREDICTED: similar to WD-repeat protein 57 [Can... 169 5e-42
>ref|XP_850117.1| PREDICTED: similar to WD repeat domain 5 [Canis familiaris]
Length = 334
Score = 607 bits (1565), Expect = e-174
Identities = 292/304 (96%), Positives = 297/304 (97%)
Frame = +1
Query: 292 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI 471
VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI
Sbjct: 31 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI 90
Query: 472 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 651
SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD
Sbjct: 91 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 150
Query: 652 ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLI 831
ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC A+ +C+K ++
Sbjct: 151 ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCGKTGNAASRCMKLIL 210
Query: 832 DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG 1011
DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG
Sbjct: 211 DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG 270
Query: 1012 GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 1191
GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW
Sbjct: 271 GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Query: 1192 KSDC 1203
KSDC
Sbjct: 331 KSDC 334
>ref|XP_537775.2| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
subunit isoform 1 [Canis familiaris]
Length = 372
Score = 187 bits (474), Expect = 3e-47
Identities = 100/313 (31%), Positives = 165/313 (52%), Gaps = 19/313 (6%)
Frame = +1
Query: 313 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS 492
K+ L+GH V+ V F P + S+S D IK+W G FE+T+ GH + D+++
Sbjct: 63 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 122
Query: 493 DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 672
LL S S D T+K+WD +C++T+ GH + V P + IVS S D+++++W+
Sbjct: 123 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 182
Query: 673 VKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDN--- 843
V+TG C+KT H + V V N+DG+LI S S D R+W A+ +C L + ++
Sbjct: 183 VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 242
Query: 844 -----PPVSFVKFS-----------PNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNE 975
P S+ S G ++L+ + D T+K+WD S G CL T GH N
Sbjct: 243 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 302
Query: 976 KYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIAS 1155
+ + +GGK+I+S ++D + +W+ + K ++ L H V S H T + +
Sbjct: 303 VRGVLFH---SGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 359
Query: 1156 AALENDKTIKLWK 1194
++ D+T+K+W+
Sbjct: 360 GSV--DQTVKVWE 370
Score = 84.7 bits (208), Expect = 2e-16
Identities = 36/103 (34%), Positives = 62/103 (60%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV 549
G +L S S DK IK+W G T+ GH + V + S ++S +DDKTL++WD
Sbjct: 270 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 329
Query: 550 SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 678
+ +C+KTL H ++V +F+ + +V+GS D++V++W+ +
Sbjct: 330 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 372
>ref|XP_854482.1| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
subunit isoform 2 [Canis familiaris]
Length = 410
Score = 187 bits (474), Expect = 3e-47
Identities = 100/313 (31%), Positives = 165/313 (52%), Gaps = 19/313 (6%)
Frame = +1
Query: 313 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS 492
K+ L+GH V+ V F P + S+S D IK+W G FE+T+ GH + D+++
Sbjct: 101 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 160
Query: 493 DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 672
LL S S D T+K+WD +C++T+ GH + V P + IVS S D+++++W+
Sbjct: 161 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
Query: 673 VKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDN--- 843
V+TG C+KT H + V V N+DG+LI S S D R+W A+ +C L + ++
Sbjct: 221 VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 280
Query: 844 -----PPVSFVKFS-----------PNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNE 975
P S+ S G ++L+ + D T+K+WD S G CL T GH N
Sbjct: 281 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 340
Query: 976 KYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIAS 1155
+ + +GGK+I+S ++D + +W+ + K ++ L H V S H T + +
Sbjct: 341 VRGVLFH---SGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 397
Query: 1156 AALENDKTIKLWK 1194
++ D+T+K+W+
Sbjct: 398 GSV--DQTVKVWE 408
Score = 84.7 bits (208), Expect = 2e-16
Identities = 36/103 (34%), Positives = 62/103 (60%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV 549
G +L S S DK IK+W G T+ GH + V + S ++S +DDKTL++WD
Sbjct: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
Query: 550 SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 678
+ +C+KTL H ++V +F+ + +V+GS D++V++W+ +
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
>ref|XP_868508.1| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
subunit isoform 3 [Canis familiaris]
Length = 345
Score = 187 bits (474), Expect = 3e-47
Identities = 100/313 (31%), Positives = 165/313 (52%), Gaps = 19/313 (6%)
Frame = +1
Query: 313 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS 492
K+ L+GH V+ V F P + S+S D IK+W G FE+T+ GH + D+++
Sbjct: 36 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 95
Query: 493 DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 672
LL S S D T+K+WD +C++T+ GH + V P + IVS S D+++++W+
Sbjct: 96 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 155
Query: 673 VKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDN--- 843
V+TG C+KT H + V V N+DG+LI S S D R+W A+ +C L + ++
Sbjct: 156 VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 215
Query: 844 -----PPVSFVKFS-----------PNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNE 975
P S+ S G ++L+ + D T+K+WD S G CL T GH N
Sbjct: 216 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 275
Query: 976 KYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIAS 1155
+ + +GGK+I+S ++D + +W+ + K ++ L H V S H T + +
Sbjct: 276 VRGVLFH---SGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 332
Query: 1156 AALENDKTIKLWK 1194
++ D+T+K+W+
Sbjct: 333 GSV--DQTVKVWE 343
Score = 84.7 bits (208), Expect = 2e-16
Identities = 36/103 (34%), Positives = 62/103 (60%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV 549
G +L S S DK IK+W G T+ GH + V + S ++S +DDKTL++WD
Sbjct: 243 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 302
Query: 550 SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 678
+ +C+KTL H ++V +F+ + +V+GS D++V++W+ +
Sbjct: 303 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 345
>ref|XP_868519.1| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
subunit isoform 5 [Canis familiaris]
Length = 415
Score = 185 bits (469), Expect = 1e-46
Identities = 100/320 (31%), Positives = 164/320 (51%), Gaps = 26/320 (8%)
Frame = +1
Query: 313 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS 492
K+ L+GH V+ V F P + S+S D IK+W G FE+T+ GH + D+++
Sbjct: 101 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 160
Query: 493 DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 672
LL S S D T+K+WD +C++T+ GH + V P + IVS S D+++++W+
Sbjct: 161 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
Query: 673 VKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTL-------- 828
V+TG C+KT H + V V N+DG+LI S S D R+W A+ +C L
Sbjct: 221 VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 280
Query: 829 ------------------IDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKT 954
+++NP K G ++L+ + D T+K+WD S G CL T
Sbjct: 281 CISWAPESSYSSISEATGSEEENPRTK--KSGKPGPFLLSGSRDKTIKMWDVSTGMCLMT 338
Query: 955 YTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHP 1134
GH N + + +GGK+I+S ++D + +W+ + K ++ L H V S H
Sbjct: 339 LVGHDNWVRGVLFH---SGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHK 395
Query: 1135 TENIIASAALENDKTIKLWK 1194
T + + ++ D+T+K+W+
Sbjct: 396 TAPYVVTGSV--DQTVKVWE 413
Score = 84.7 bits (208), Expect = 2e-16
Identities = 36/103 (34%), Positives = 62/103 (60%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV 549
G +L S S DK IK+W G T+ GH + V + S ++S +DDKTL++WD
Sbjct: 313 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 372
Query: 550 SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 678
+ +C+KTL H ++V +F+ + +V+GS D++V++W+ +
Sbjct: 373 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 415
>ref|XP_534593.2| PREDICTED: similar to CG7568-PA [Canis familiaris]
Length = 415
Score = 185 bits (469), Expect = 1e-46
Identities = 103/293 (35%), Positives = 162/293 (55%), Gaps = 1/293 (0%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFS-PNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD 495
TL GH V ++ F+ P G+ +A+ S DK K+W GK T GH I ++++
Sbjct: 129 TLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQ 188
Query: 496 SNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 675
S L+ + S D T K+WD+ SG+ + TL+GHS + +FN + IV+GSFD +V +W+
Sbjct: 189 STLVATGSMDTTAKLWDIQSGEEVFTLRGHSAEIISLSFNTSGDRIVTGSFDHTVAVWEA 248
Query: 676 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVS 855
TG+ + TL H +S+ FN D SLI++ S D C +WD ++G+C+ TL D+ +
Sbjct: 249 DTGRKVYTLIGHCAEISSALFNWDCSLILTGSMDKTCMLWDASNGKCVATLTGHDDEILD 308
Query: 856 FVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGS 1035
F GK I A+ D T +++ + KCL GH+ E I N G +++GS
Sbjct: 309 SC-FDYTGKLIATASADGTARVFSAATRKCLTKLEGHEGEISKISFN---PQGNRLLTGS 364
Query: 1036 EDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 1194
D IW+ QT + +Q L+GHTD + S A + +II + + D T ++W+
Sbjct: 365 ADETARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGDIIITGS--KDNTCRIWR 415
Score = 170 bits (431), Expect = 3e-42
Identities = 90/291 (30%), Positives = 161/291 (55%), Gaps = 1/291 (0%)
Frame = +1
Query: 322 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD-S 498
L H +++V + +G + S D+ K+W G+ T+ GH+ + +A+++
Sbjct: 88 LRAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELHTLEGHRNVVYAIAFNNPYG 147
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 678
+ + + S DKT K+W V +GKC T +GH+ + C +FNPQS L+ +GS D + ++WD++
Sbjct: 148 DKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQ 207
Query: 679 TGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSF 858
+G+ + TL HS + ++ FN G IV+ S+D +W+ +G+ + TLI +S
Sbjct: 208 SGEEVFTLRGHSAEIISLSFNTSGDRIVTGSFDHTVAVWEADTGRKVYTLI-GHCAEISS 266
Query: 859 VKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE 1038
F+ + IL ++D T LWD S GKC+ T TGH +E + + F T GK I + S
Sbjct: 267 ALFNWDCSLILTGSMDKTCMLWDASNGKCVATLTGHDDE--ILDSCFDYT-GKLIATASA 323
Query: 1039 DNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 1191
D +++ T++ + KL+GH + + +P N + + + D+T ++W
Sbjct: 324 DGTARVFSAATRKCLTKLEGHEGEISKISFNPQGNRLLTGSA--DETARIW 372
Score = 138 bits (347), Expect = 2e-32
Identities = 68/203 (33%), Positives = 111/203 (54%)
Frame = +1
Query: 316 FTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD 495
FTL GH+ + S+ F+ +G+ + + S D + +W A G+ T+ GH IS ++ D
Sbjct: 213 FTLRGHSAEIISLSFNTSGDRIVTGSFDHTVAVWEADTGRKVYTLIGHCAEISSALFNWD 272
Query: 496 SNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 675
+L+++ S DKT +WD S+GKC+ TL GH + + F+ LI + S D + R++
Sbjct: 273 CSLILTGSMDKTCMLWDASNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARVFSA 332
Query: 676 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVS 855
T KCL L H +S + FN G+ +++ S D RIWD +GQCL+ L + +
Sbjct: 333 ATRKCLTKLEGHEGEISKISFNPQGNRLLTGSADETARIWDAQTGQCLQVL-EGHTDEIF 391
Query: 856 FVKFSPNGKYILAATLDNTLKLW 924
F+ G I+ + DNT ++W
Sbjct: 392 SCAFNYKGDIIITGSKDNTCRIW 414
Score = 105 bits (263), Expect = 9e-23
Identities = 58/169 (34%), Positives = 90/169 (53%)
Frame = +1
Query: 694 KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSP 873
K L AH P++ V N+ GS ++ SYD C++WDTASG+ L TL N + +P
Sbjct: 86 KVLRAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELHTLEGHRNVVYAIAFNNP 145
Query: 874 NGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVY 1053
G I + D T KLW GKC T+ GH E C+ N T + +GS D
Sbjct: 146 YGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQST---LVATGSMDTTAK 202
Query: 1054 IWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSD 1200
+W++Q+ E V L+GH+ +IS + + + + I + + D T+ +W++D
Sbjct: 203 LWDIQSGEEVFTLRGHSAEIISLSFNTSGDRIVTGSF--DHTVAVWEAD 249
>ref|XP_532689.2| PREDICTED: similar to F-box protein FBW7 isoform 3 isoform 1 [Canis
familiaris]
Length = 589
Score = 169 bits (429), Expect = 5e-42
Identities = 98/284 (34%), Positives = 162/284 (57%), Gaps = 10/284 (3%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIW 543
G + S S D +K+W A GK +T+ GH G+ WSS N+++S S D+TLK+W
Sbjct: 273 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVW 328
Query: 544 DVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPV 723
+ +G+C+ TL GH++ V C + + + +VSGS D ++R+WD++TG+CL L H V
Sbjct: 329 NAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAV 386
Query: 724 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATL 903
V + DG +VS +YD + ++WD + CL TL N S ++F +G ++++ +L
Sbjct: 387 RCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYS-LQF--DGIHVVSGSL 441
Query: 904 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG-----KWIVSGSEDNLVYIWNLQ 1068
D ++++WD G C+ T TGH+ S+T G +VSG+ D+ V IW+++
Sbjct: 442 DTSIRVWDVETGNCIHTLTGHQ----------SLTSGMELKDNILVSGNADSTVKIWDIK 491
Query: 1069 TKEIVQKLQG---HTDVVISTACHPTENIIASAALENDKTIKLW 1191
T + +Q LQG H V T +N + +++ +D T+KLW
Sbjct: 492 TGQCLQTLQGPNKHQSAV--TCLQFNKNFVITSS--DDGTVKLW 531
Score = 92.4 bits (228), Expect = 1e-18
Identities = 50/131 (38%), Positives = 79/131 (60%), Gaps = 3/131 (2%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 498
TL GHT V S++F +G + S S D I++W G T++GH+ S +
Sbjct: 418 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD-- 473
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKG---HSNYVFCCNFNPQSNLIVSGSFDESVRIW 669
N+LVS + D T+KIWD+ +G+CL+TL+G H + V C FN N +++ S D +V++W
Sbjct: 474 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFN--KNFVITSSDDGTVKLW 531
Query: 670 DVKTGKCLKTL 702
D+KTG+ ++ L
Sbjct: 532 DLKTGEFIRNL 542
>ref|XP_867720.1| PREDICTED: similar to F-box protein FBW7 isoform 2 isoform 5 [Canis
familiaris]
Length = 637
Score = 169 bits (429), Expect = 5e-42
Identities = 98/284 (34%), Positives = 162/284 (57%), Gaps = 10/284 (3%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIW 543
G + S S D +K+W A GK +T+ GH G+ WSS N+++S S D+TLK+W
Sbjct: 321 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVW 376
Query: 544 DVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPV 723
+ +G+C+ TL GH++ V C + + + +VSGS D ++R+WD++TG+CL L H V
Sbjct: 377 NAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAV 434
Query: 724 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATL 903
V + DG +VS +YD + ++WD + CL TL N S ++F +G ++++ +L
Sbjct: 435 RCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYS-LQF--DGIHVVSGSL 489
Query: 904 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG-----KWIVSGSEDNLVYIWNLQ 1068
D ++++WD G C+ T TGH+ S+T G +VSG+ D+ V IW+++
Sbjct: 490 DTSIRVWDVETGNCIHTLTGHQ----------SLTSGMELKDNILVSGNADSTVKIWDIK 539
Query: 1069 TKEIVQKLQG---HTDVVISTACHPTENIIASAALENDKTIKLW 1191
T + +Q LQG H V T +N + +++ +D T+KLW
Sbjct: 540 TGQCLQTLQGPNKHQSAV--TCLQFNKNFVITSS--DDGTVKLW 579
Score = 92.4 bits (228), Expect = 1e-18
Identities = 50/131 (38%), Positives = 79/131 (60%), Gaps = 3/131 (2%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 498
TL GHT V S++F +G + S S D I++W G T++GH+ S +
Sbjct: 466 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD-- 521
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKG---HSNYVFCCNFNPQSNLIVSGSFDESVRIW 669
N+LVS + D T+KIWD+ +G+CL+TL+G H + V C FN N +++ S D +V++W
Sbjct: 522 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFN--KNFVITSSDDGTVKLW 579
Query: 670 DVKTGKCLKTL 702
D+KTG+ ++ L
Sbjct: 580 DLKTGEFIRNL 590
>ref|XP_853624.1| PREDICTED: similar to F-box protein FBW7 isoform 2 isoform 2 [Canis
familiaris]
Length = 627
Score = 169 bits (429), Expect = 5e-42
Identities = 98/284 (34%), Positives = 162/284 (57%), Gaps = 10/284 (3%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIW 543
G + S S D +K+W A GK +T+ GH G+ WSS N+++S S D+TLK+W
Sbjct: 311 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVW 366
Query: 544 DVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPV 723
+ +G+C+ TL GH++ V C + + + +VSGS D ++R+WD++TG+CL L H V
Sbjct: 367 NAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAV 424
Query: 724 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATL 903
V + DG +VS +YD + ++WD + CL TL N S ++F +G ++++ +L
Sbjct: 425 RCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYS-LQF--DGIHVVSGSL 479
Query: 904 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG-----KWIVSGSEDNLVYIWNLQ 1068
D ++++WD G C+ T TGH+ S+T G +VSG+ D+ V IW+++
Sbjct: 480 DTSIRVWDVETGNCIHTLTGHQ----------SLTSGMELKDNILVSGNADSTVKIWDIK 529
Query: 1069 TKEIVQKLQG---HTDVVISTACHPTENIIASAALENDKTIKLW 1191
T + +Q LQG H V T +N + +++ +D T+KLW
Sbjct: 530 TGQCLQTLQGPNKHQSAV--TCLQFNKNFVITSS--DDGTVKLW 569
Score = 92.4 bits (228), Expect = 1e-18
Identities = 50/131 (38%), Positives = 79/131 (60%), Gaps = 3/131 (2%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 498
TL GHT V S++F +G + S S D I++W G T++GH+ S +
Sbjct: 456 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD-- 511
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKG---HSNYVFCCNFNPQSNLIVSGSFDESVRIW 669
N+LVS + D T+KIWD+ +G+CL+TL+G H + V C FN N +++ S D +V++W
Sbjct: 512 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFN--KNFVITSSDDGTVKLW 569
Query: 670 DVKTGKCLKTL 702
D+KTG+ ++ L
Sbjct: 570 DLKTGEFIRNL 580
>ref|XP_854730.1| PREDICTED: similar to WD-repeat protein 57 [Canis familiaris]
Length = 358
Score = 169 bits (429), Expect = 5e-42
Identities = 100/290 (34%), Positives = 160/290 (55%), Gaps = 10/290 (3%)
Frame = +1
Query: 322 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAY-DGKFEKTISGHKLGISDVAWSSDS 498
L+GH V KF PNG LAS+ D+LI +W Y D T+ GH + ++ +++D
Sbjct: 63 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 122
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCC---NFNPQSNLIVSGSFDESVRIW 669
++L SAS DKT+ +WD +G+ +K LKGH+++V C PQ L+ +GS D +V++W
Sbjct: 123 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQ--LVCTGSDDGTVKLW 180
Query: 670 DVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 849
D++ ++T ++ V AV FN I+S D ++WD + T+ +
Sbjct: 181 DIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADS- 238
Query: 850 VSFVKFSPNGKYILAATLDNTLKLWDYS----KGKCLKTYTG--HKNEKYCIFANFSVTG 1011
V+ + S G Y+L+ +DNT+++WD K +C+K + G H EK + ++S G
Sbjct: 239 VTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDG 298
Query: 1012 GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAA 1161
K I +GS D VY+W+ ++ I+ KL GH + A HP E II SA+
Sbjct: 299 SK-IAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIILSAS 347
Score = 109 bits (273), Expect = 6e-24
Identities = 61/208 (29%), Positives = 107/208 (51%), Gaps = 2/208 (0%)
Frame = +1
Query: 574 LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKC--LKTLPAHSDPVSAVHFNRD 747
L GH V+CC F+P + + S FD + +W+V G C TL HS V +H+N D
Sbjct: 63 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVY-GDCDNYATLKGHSGAVMELHYNTD 121
Query: 748 GSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWD 927
GS++ S+S D +WD+ +G+ +K L + S + + + D T+KLWD
Sbjct: 122 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 181
Query: 928 YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTD 1107
K ++T+ +N + F+ T + I+SG DN + +W+L+ ++ ++GH D
Sbjct: 182 IRKKAAIQTF---QNTYQVLAVTFNDTSDQ-IISGGIDNDIKVWDLRQNKLTYTMRGHAD 237
Query: 1108 VVISTACHPTENIIASAALENDKTIKLW 1191
V + + + S A++N T+++W
Sbjct: 238 SVTGLSLSSEGSYLLSNAMDN--TVRVW 263
Score = 84.3 bits (207), Expect = 3e-16
Identities = 45/157 (28%), Positives = 83/157 (52%), Gaps = 8/157 (5%)
Frame = +1
Query: 331 HTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLV 510
+T V +V F+ + + S D IK+W K T+ GH ++ ++ SS+ + L+
Sbjct: 193 NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLL 252
Query: 511 SASDDKTLKIWDVS----SGKCLKTLKGH----SNYVFCCNFNPQSNLIVSGSFDESVRI 666
S + D T+++WDV +C+K +G+ + C+++P + I +GS D V +
Sbjct: 253 SNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYV 312
Query: 667 WDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYD 777
WD + + L LP H+ ++ V F+ D +I+S+S D
Sbjct: 313 WDTTSRRILYKLPGHAGSINEVAFHPDEPIILSASSD 349
Score = 62.4 bits (150), Expect = 1e-09
Identities = 30/131 (22%), Positives = 65/131 (49%), Gaps = 8/131 (6%)
Frame = +1
Query: 310 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGK--------FEKTISGHKL 465
L +T+ GH +V+ + S G +L S++ D +++W F+ + +
Sbjct: 228 LTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEK 287
Query: 466 GISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGS 645
+ +WS D + + + S D+ + +WD +S + L L GH+ + F+P +I+S S
Sbjct: 288 NLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIILSAS 347
Query: 646 FDESVRIWDVK 678
D+ + + +++
Sbjct: 348 SDKRLYMGEIQ 358
Database: RefSeqCP
Posted date: Aug 1, 2006 9:25 PM
Number of letters in database: 19,266,565
Number of sequences in database: 33,732
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,890,052
Number of Sequences: 33732
Number of extensions: 1311017
Number of successful extensions: 10556
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 4765
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7430
length of database: 19,266,565
effective HSP length: 107
effective length of database: 15,657,241
effective search space used: 6121981231
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqHP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= OVR01_0046_B07
(1498 letters)
Database: RefSeqHP
39,411 sequences; 17,774,539 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_438172.1| WD repeat domain 5 [Homo sapiens] 632 0.0
Alignment gi|NP_060058.1| WD repeat domain 5 [Homo sapiens] 632 0.0
Alignment gi|NP_061942.2| WD repeat domain 5B [Homo sapiens] 568 e-162
Alignment gi|NP_000421.1| platelet-activating factor acetylhydrolase, iso... 187 3e-47
Alignment gi|NP_849143.1| hypothetical protein LOC164781 [Homo sapiens] 186 3e-47
Alignment gi|NP_004805.1| WD repeat domain 57 (U5 snRNP specific) [Homo s... 170 3e-42
Alignment gi|NP_060785.2| F-box protein FBW7 isoform 2 [Homo sapiens] 169 4e-42
Alignment gi|NP_001013433.1| F-box protein FBW7 isoform 3 [Homo sapiens] 169 4e-42
Alignment gi|NP_361014.1| F-box protein FBW7 isoform 1 [Homo sapiens] 169 4e-42
Alignment gi|NP_115708.1| mitogen-activated protein kinase organizer 1 [H... 154 2e-37
>ref|NP_438172.1| WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 632 bits (1629), Expect = 0.0
Identities = 304/304 (100%), Positives = 304/304 (100%)
Frame = +1
Query: 292 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI 471
VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI
Sbjct: 31 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI 90
Query: 472 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 651
SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD
Sbjct: 91 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 150
Query: 652 ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLI 831
ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLI
Sbjct: 151 ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLI 210
Query: 832 DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG 1011
DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG
Sbjct: 211 DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG 270
Query: 1012 GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 1191
GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW
Sbjct: 271 GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Query: 1192 KSDC 1203
KSDC
Sbjct: 331 KSDC 334
>ref|NP_060058.1| WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 632 bits (1629), Expect = 0.0
Identities = 304/304 (100%), Positives = 304/304 (100%)
Frame = +1
Query: 292 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI 471
VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI
Sbjct: 31 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI 90
Query: 472 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 651
SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD
Sbjct: 91 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 150
Query: 652 ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLI 831
ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLI
Sbjct: 151 ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLI 210
Query: 832 DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG 1011
DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG
Sbjct: 211 DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG 270
Query: 1012 GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 1191
GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW
Sbjct: 271 GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Query: 1192 KSDC 1203
KSDC
Sbjct: 331 KSDC 334
>ref|NP_061942.2| WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 568 bits (1465), Expect = e-162
Identities = 269/301 (89%), Positives = 284/301 (94%)
Frame = +1
Query: 298 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISD 477
PNYALK TL GHT+AVSSVKFSPNGEWLASSSAD+LI IWGAYDGK+EKT+ GH L ISD
Sbjct: 29 PNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISD 88
Query: 478 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDES 657
VAWSSDS+ LVSASDDKTLK+WDV SGKCLKTLKGHSNYVFCCNFNP SNLI+SGSFDE+
Sbjct: 89 VAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDET 148
Query: 658 VRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDD 837
V+IW+VKTGKCLKTL AHSDPVSAVHFN GSLIVS SYDGLCRIWD ASGQCLKTL+DD
Sbjct: 149 VKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDD 208
Query: 838 DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK 1017
DNPPVSFVKFSPNGKYIL ATLDNTLKLWDYS+G+CLKTYTGHKNEKYCIFANFSVTGGK
Sbjct: 209 DNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGK 268
Query: 1018 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS 1197
WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVIS ACHPTEN+IASAALENDKTIKLW S
Sbjct: 269 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLWMS 328
Query: 1198 D 1200
+
Sbjct: 329 N 329
Score = 121 bits (303), Expect = 2e-27
Identities = 77/233 (33%), Positives = 120/233 (51%), Gaps = 1/233 (0%)
Frame = +1
Query: 496 SNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 675
+ L +S+S +++ ++ + + TL GH+ V F+P + S S D + IW
Sbjct: 11 AQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGA 70
Query: 676 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVS 855
GK KTL H+ +S V ++ D S +VS+S D ++WD SG+CLKTL N V
Sbjct: 71 YDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSN-YVF 129
Query: 856 FVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGS 1035
F+P I++ + D T+K+W+ GKCLKT + H + + N S G IVSGS
Sbjct: 130 CCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCS---GSLIVSGS 186
Query: 1036 EDNLVYIWNLQTKEIVQKLQGHTDVVIS-TACHPTENIIASAALENDKTIKLW 1191
D L IW+ + + ++ L + +S P I +A L+N T+KLW
Sbjct: 187 YDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDN--TLKLW 237
>ref|NP_000421.1| platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit
(45kD) [Homo sapiens]
Length = 410
Score = 187 bits (474), Expect = 3e-47
Identities = 100/313 (31%), Positives = 165/313 (52%), Gaps = 19/313 (6%)
Frame = +1
Query: 313 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS 492
K+ L+GH V+ V F P + S+S D IK+W G FE+T+ GH + D+++
Sbjct: 101 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 160
Query: 493 DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 672
LL S S D T+K+WD +C++T+ GH + V P + IVS S D+++++W+
Sbjct: 161 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
Query: 673 VKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDN--- 843
V+TG C+KT H + V V N+DG+LI S S D R+W A+ +C L + ++
Sbjct: 221 VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 280
Query: 844 -----PPVSFVKFS-----------PNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNE 975
P S+ S G ++L+ + D T+K+WD S G CL T GH N
Sbjct: 281 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 340
Query: 976 KYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIAS 1155
+ + +GGK+I+S ++D + +W+ + K ++ L H V S H T + +
Sbjct: 341 VRGVLFH---SGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 397
Query: 1156 AALENDKTIKLWK 1194
++ D+T+K+W+
Sbjct: 398 GSV--DQTVKVWE 408
Score = 84.7 bits (208), Expect = 2e-16
Identities = 36/103 (34%), Positives = 62/103 (60%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV 549
G +L S S DK IK+W G T+ GH + V + S ++S +DDKTL++WD
Sbjct: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
Query: 550 SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 678
+ +C+KTL H ++V +F+ + +V+GS D++V++W+ +
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
>ref|NP_849143.1| hypothetical protein LOC164781 [Homo sapiens]
Length = 415
Score = 186 bits (473), Expect = 3e-47
Identities = 100/293 (34%), Positives = 161/293 (54%), Gaps = 1/293 (0%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFS-PNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD 495
TL GH V ++ F+ P G+ +A+ S DK K+W GK T GH I ++++
Sbjct: 129 TLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQ 188
Query: 496 SNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 675
S L+ + S D T K+WD+ +G+ + TL+GHS + +FN + I++GSFD +V +WD
Sbjct: 189 STLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDA 248
Query: 676 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVS 855
TG+ + L H +S+ FN D SLI++ S D C++WD +G+C+ TL D+ +
Sbjct: 249 DTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILD 308
Query: 856 FVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGS 1035
F GK I A+ D T +++ + KC+ GH+ E I N G +++GS
Sbjct: 309 SC-FDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFN---PQGNHLLTGS 364
Query: 1036 EDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 1194
D IW+ QT + +Q L+GHTD + S A + NI+ + + D T ++W+
Sbjct: 365 SDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGS--KDNTCRIWR 415
Score = 175 bits (443), Expect = 1e-43
Identities = 91/291 (31%), Positives = 161/291 (55%), Gaps = 1/291 (0%)
Frame = +1
Query: 322 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD-S 498
L H +++V + +G + S D+ K+W G+ T+ GH+ + +A+++
Sbjct: 88 LKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYG 147
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 678
+ + + S DKT K+W V +GKC T +GH+ + C +FNPQS L+ +GS D + ++WD++
Sbjct: 148 DKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQ 207
Query: 679 TGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSF 858
G+ + TL HS + ++ FN G I++ S+D +WD +G+ + LI +S
Sbjct: 208 NGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILI-GHCAEISS 266
Query: 859 VKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE 1038
F+ + IL ++D T KLWD + GKC+ T TGH +E + + F T GK I + S
Sbjct: 267 ASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDE--ILDSCFDYT-GKLIATASA 323
Query: 1039 DNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 1191
D I++ T++ + KL+GH + + +P N + + + +DKT ++W
Sbjct: 324 DGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGS--SDKTARIW 372
Score = 136 bits (342), Expect = 5e-32
Identities = 65/203 (32%), Positives = 112/203 (55%)
Frame = +1
Query: 316 FTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD 495
+TL GH+ + S+ F+ +G+ + + S D + +W A G+ + GH IS +++ D
Sbjct: 213 YTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWD 272
Query: 496 SNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 675
+L+++ S DKT K+WD ++GKC+ TL GH + + F+ LI + S D + RI+
Sbjct: 273 CSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSA 332
Query: 676 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVS 855
T KC+ L H +S + FN G+ +++ S D RIWD +GQCL+ L + +
Sbjct: 333 ATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVL-EGHTDEIF 391
Query: 856 FVKFSPNGKYILAATLDNTLKLW 924
F+ G ++ + DNT ++W
Sbjct: 392 SCAFNYKGNIVITGSKDNTCRIW 414
Score = 105 bits (262), Expect = 1e-22
Identities = 58/169 (34%), Positives = 88/169 (52%)
Frame = +1
Query: 694 KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSP 873
K L AH P++ V N+ GS ++ SYD C++WDTASG+ L TL N + +P
Sbjct: 86 KVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNP 145
Query: 874 NGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVY 1053
G I + D T KLW GKC T+ GH E C+ N T + +GS D
Sbjct: 146 YGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQST---LVATGSMDTTAK 202
Query: 1054 IWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSD 1200
+W++Q E V L+GH+ +IS + + + + I + + D T+ +W +D
Sbjct: 203 LWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSF--DHTVVVWDAD 249
>ref|NP_004805.1| WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 170 bits (430), Expect = 3e-42
Identities = 99/288 (34%), Positives = 160/288 (55%), Gaps = 8/288 (2%)
Frame = +1
Query: 322 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAY-DGKFEKTISGHKLGISDVAWSSDS 498
L+GH V KF PNG LAS+ D+LI +W Y D T+ GH + ++ +++D
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQS-NLIVSGSFDESVRIWDV 675
++L SAS DKT+ +WD +G+ +K LKGH+++V C +S L+ +GS D +V++WD+
Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWDI 181
Query: 676 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVS 855
+ ++T ++ V AV FN I+S D ++WD + T+ + V+
Sbjct: 182 RKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADS-VT 239
Query: 856 FVKFSPNGKYILAATLDNTLKLWDYS----KGKCLKTYTG--HKNEKYCIFANFSVTGGK 1017
+ S G Y+L+ +DNT+++WD K +C+K + G H EK + ++S G K
Sbjct: 240 GLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSK 299
Query: 1018 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAA 1161
I +GS D VY+W+ ++ I+ KL GH + A HP E II SA+
Sbjct: 300 -IAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISAS 346
Score = 110 bits (275), Expect = 3e-24
Identities = 61/208 (29%), Positives = 108/208 (51%), Gaps = 2/208 (0%)
Frame = +1
Query: 574 LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKC--LKTLPAHSDPVSAVHFNRD 747
L GH V+CC F+P + + S FD + +W+V G C TL HS V +H+N D
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVY-GDCDNYATLKGHSGAVMELHYNTD 120
Query: 748 GSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWD 927
GS++ S+S D +WD+ +G+ +K L + S + + + + D T+KLWD
Sbjct: 121 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWD 180
Query: 928 YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTD 1107
K ++T+ +N + F+ T + I+SG DN + +W+L+ ++ ++GH D
Sbjct: 181 IRKKAAIQTF---QNTYQVLAVTFNDTSDQ-IISGGIDNDIKVWDLRQNKLTYTMRGHAD 236
Query: 1108 VVISTACHPTENIIASAALENDKTIKLW 1191
V + + + S A++N T+++W
Sbjct: 237 SVTGLSLSSEGSYLLSNAMDN--TVRVW 262
>ref|NP_060785.2| F-box protein FBW7 isoform 2 [Homo sapiens]
Length = 627
Score = 169 bits (429), Expect = 4e-42
Identities = 98/284 (34%), Positives = 162/284 (57%), Gaps = 10/284 (3%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIW 543
G + S S D +K+W A GK +T+ GH G+ WSS N+++S S D+TLK+W
Sbjct: 311 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVW 366
Query: 544 DVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPV 723
+ +G+C+ TL GH++ V C + + + +VSGS D ++R+WD++TG+CL L H V
Sbjct: 367 NAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAV 424
Query: 724 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATL 903
V + DG +VS +YD + ++WD + CL TL N S ++F +G ++++ +L
Sbjct: 425 RCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYS-LQF--DGIHVVSGSL 479
Query: 904 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG-----KWIVSGSEDNLVYIWNLQ 1068
D ++++WD G C+ T TGH+ S+T G +VSG+ D+ V IW+++
Sbjct: 480 DTSIRVWDVETGNCIHTLTGHQ----------SLTSGMELKDNILVSGNADSTVKIWDIK 529
Query: 1069 TKEIVQKLQG---HTDVVISTACHPTENIIASAALENDKTIKLW 1191
T + +Q LQG H V T +N + +++ +D T+KLW
Sbjct: 530 TGQCLQTLQGPNKHQSAV--TCLQFNKNFVITSS--DDGTVKLW 569
Score = 92.4 bits (228), Expect = 9e-19
Identities = 50/131 (38%), Positives = 79/131 (60%), Gaps = 3/131 (2%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 498
TL GHT V S++F +G + S S D I++W G T++GH+ S +
Sbjct: 456 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD-- 511
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKG---HSNYVFCCNFNPQSNLIVSGSFDESVRIW 669
N+LVS + D T+KIWD+ +G+CL+TL+G H + V C FN N +++ S D +V++W
Sbjct: 512 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFN--KNFVITSSDDGTVKLW 569
Query: 670 DVKTGKCLKTL 702
D+KTG+ ++ L
Sbjct: 570 DLKTGEFIRNL 580
>ref|NP_001013433.1| F-box protein FBW7 isoform 3 [Homo sapiens]
Length = 589
Score = 169 bits (429), Expect = 4e-42
Identities = 98/284 (34%), Positives = 162/284 (57%), Gaps = 10/284 (3%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIW 543
G + S S D +K+W A GK +T+ GH G+ WSS N+++S S D+TLK+W
Sbjct: 273 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVW 328
Query: 544 DVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPV 723
+ +G+C+ TL GH++ V C + + + +VSGS D ++R+WD++TG+CL L H V
Sbjct: 329 NAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAV 386
Query: 724 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATL 903
V + DG +VS +YD + ++WD + CL TL N S ++F +G ++++ +L
Sbjct: 387 RCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYS-LQF--DGIHVVSGSL 441
Query: 904 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG-----KWIVSGSEDNLVYIWNLQ 1068
D ++++WD G C+ T TGH+ S+T G +VSG+ D+ V IW+++
Sbjct: 442 DTSIRVWDVETGNCIHTLTGHQ----------SLTSGMELKDNILVSGNADSTVKIWDIK 491
Query: 1069 TKEIVQKLQG---HTDVVISTACHPTENIIASAALENDKTIKLW 1191
T + +Q LQG H V T +N + +++ +D T+KLW
Sbjct: 492 TGQCLQTLQGPNKHQSAV--TCLQFNKNFVITSS--DDGTVKLW 531
Score = 92.4 bits (228), Expect = 9e-19
Identities = 50/131 (38%), Positives = 79/131 (60%), Gaps = 3/131 (2%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 498
TL GHT V S++F +G + S S D I++W G T++GH+ S +
Sbjct: 418 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD-- 473
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKG---HSNYVFCCNFNPQSNLIVSGSFDESVRIW 669
N+LVS + D T+KIWD+ +G+CL+TL+G H + V C FN N +++ S D +V++W
Sbjct: 474 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFN--KNFVITSSDDGTVKLW 531
Query: 670 DVKTGKCLKTL 702
D+KTG+ ++ L
Sbjct: 532 DLKTGEFIRNL 542
>ref|NP_361014.1| F-box protein FBW7 isoform 1 [Homo sapiens]
Length = 707
Score = 169 bits (429), Expect = 4e-42
Identities = 98/284 (34%), Positives = 162/284 (57%), Gaps = 10/284 (3%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIW 543
G + S S D +K+W A GK +T+ GH G+ WSS N+++S S D+TLK+W
Sbjct: 391 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVW 446
Query: 544 DVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPV 723
+ +G+C+ TL GH++ V C + + + +VSGS D ++R+WD++TG+CL L H V
Sbjct: 447 NAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAV 504
Query: 724 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATL 903
V + DG +VS +YD + ++WD + CL TL N S ++F +G ++++ +L
Sbjct: 505 RCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYS-LQF--DGIHVVSGSL 559
Query: 904 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG-----KWIVSGSEDNLVYIWNLQ 1068
D ++++WD G C+ T TGH+ S+T G +VSG+ D+ V IW+++
Sbjct: 560 DTSIRVWDVETGNCIHTLTGHQ----------SLTSGMELKDNILVSGNADSTVKIWDIK 609
Query: 1069 TKEIVQKLQG---HTDVVISTACHPTENIIASAALENDKTIKLW 1191
T + +Q LQG H V T +N + +++ +D T+KLW
Sbjct: 610 TGQCLQTLQGPNKHQSAV--TCLQFNKNFVITSS--DDGTVKLW 649
Score = 92.4 bits (228), Expect = 9e-19
Identities = 50/131 (38%), Positives = 79/131 (60%), Gaps = 3/131 (2%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 498
TL GHT V S++F +G + S S D I++W G T++GH+ S +
Sbjct: 536 TLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD-- 591
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKG---HSNYVFCCNFNPQSNLIVSGSFDESVRIW 669
N+LVS + D T+KIWD+ +G+CL+TL+G H + V C FN N +++ S D +V++W
Sbjct: 592 NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFN--KNFVITSSDDGTVKLW 649
Query: 670 DVKTGKCLKTL 702
D+KTG+ ++ L
Sbjct: 650 DLKTGEFIRNL 660
>ref|NP_115708.1| mitogen-activated protein kinase organizer 1 [Homo sapiens]
Length = 315
Score = 154 bits (388), Expect = 2e-37
Identities = 94/289 (32%), Positives = 155/289 (53%), Gaps = 2/289 (0%)
Frame = +1
Query: 340 AVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSAS 519
AV +V+F+ +G + + +DK +K+W G +T SGH + D A S D++ L S
Sbjct: 27 AVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGG 86
Query: 520 DDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK--CL 693
DK + +WDV+SG+ ++ +GH+ V FN ++ +I+SGS D S+R WD ++ + +
Sbjct: 87 GDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPV 146
Query: 694 KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSP 873
+TL D VS+V + I++ S DG R +D GQ + P++ FS
Sbjct: 147 QTLDEARDGVSSVKVS--DHEILAGSVDGRVRRYDLRMGQLFSDYV---GSPITCTCFSR 201
Query: 874 NGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVY 1053
+G+ L ++LD+TL+L D G+ L Y GHKN++Y + S +VS SED V+
Sbjct: 202 DGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLS-ERDTHVVSCSEDGKVF 260
Query: 1054 IWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSD 1200
W+L + L + VV S A HPTE + +A +++ W+ +
Sbjct: 261 FWDLVEGALALALPVGSGVVQSLAYHPTEPCLLTAM---GGSVQCWREE 306
Score = 55.8 bits (133), Expect = 9e-08
Identities = 34/123 (27%), Positives = 58/123 (47%)
Frame = +1
Query: 559 KCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 738
K LKTL V FN N ++ D+++++W+ G L+T H V
Sbjct: 16 KRLKTLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAG 75
Query: 739 NRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLK 918
+ D S + S D +WD ASGQ ++ V+ V+F+ IL+ ++D++++
Sbjct: 76 SFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAG-KVNTVQFNEEATVILSGSIDSSIR 134
Query: 919 LWD 927
WD
Sbjct: 135 CWD 137
Database: RefSeqHP
Posted date: Aug 2, 2006 12:57 AM
Number of letters in database: 17,774,539
Number of sequences in database: 39,411
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,020,392
Number of Sequences: 39411
Number of extensions: 1299425
Number of successful extensions: 9795
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 5105
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7443
length of database: 17,774,539
effective HSP length: 106
effective length of database: 13,596,973
effective search space used: 5330013416
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqSP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= OVR01_0046_B07
(1498 letters)
Database: RefSeqSP
1040 sequences; 434,620 total letters
Searching...done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_999415.1| platelet-activating factor acetylhydrolase Ib-a... 186 2e-48
Alignment gi|NP_999497.1| G-beta like protein [Sus scrofa] 122 2e-29
Alignment gi|NP_001012296.1| fizzy/cell division cycle 20 related 1 [Sus ... 76 2e-15
>ref|NP_999415.1| platelet-activating factor acetylhydrolase Ib-alpha subunit [Sus
scrofa]
Length = 410
Score = 186 bits (471), Expect = 2e-48
Identities = 99/313 (31%), Positives = 165/313 (52%), Gaps = 19/313 (6%)
Frame = +1
Query: 313 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS 492
K+ L+GH V+ V F P + S+S D IK+W G FE+T+ GH + D+++
Sbjct: 101 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 160
Query: 493 DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 672
LL S S D T+K+WD +C++T+ GH + V P + IVS + D+++++W+
Sbjct: 161 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSAARDKTIKMWE 220
Query: 673 VKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDN--- 843
V+TG C+KT H + V V N+DG+LI S S D R+W A+ +C L + ++
Sbjct: 221 VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 280
Query: 844 -----PPVSFVKFS-----------PNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNE 975
P S+ S G ++L+ + D T+K+WD S G CL T GH N
Sbjct: 281 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 340
Query: 976 KYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIAS 1155
+ + +GGK+I+S ++D + +W+ + K ++ L H V S H T + +
Sbjct: 341 VRGVLFH---SGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 397
Query: 1156 AALENDKTIKLWK 1194
++ D+T+K+W+
Sbjct: 398 GSV--DQTVKVWE 408
Score = 84.7 bits (208), Expect = 5e-18
Identities = 36/103 (34%), Positives = 62/103 (60%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV 549
G +L S S DK IK+W G T+ GH + V + S ++S +DDKTL++WD
Sbjct: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
Query: 550 SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 678
+ +C+KTL H ++V +F+ + +V+GS D++V++W+ +
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
>ref|NP_999497.1| G-beta like protein [Sus scrofa]
Length = 317
Score = 122 bits (307), Expect = 2e-29
Identities = 87/268 (32%), Positives = 138/268 (51%), Gaps = 13/268 (4%)
Frame = +1
Query: 301 NYAL-KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISD 477
NY + + L GH+ VS V S +G++ S S D +++W G + GH +
Sbjct: 51 NYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS 110
Query: 478 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK--GHSNYVFCCNFNPQSN--LIVSGS 645
VA+SSD+ +VS S DKT+K+W+ + G C T++ HS +V C F+P S+ +IVS
Sbjct: 111 VAFSSDNRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCG 169
Query: 646 FDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKT 825
+D+ V++W++ K H+ ++ V + DGSL S DG +WD G+ L T
Sbjct: 170 WDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT 229
Query: 826 LIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTY-------TGHKNEK-Y 981
L D ++ + FSPN +Y L A ++K+WD +GK + T K E
Sbjct: 230 L--DGGDIINALCFSPN-RYWLCAATGPSIKIWDL-EGKIIVDELKQEVISTSSKAEPPQ 285
Query: 982 CIFANFSVTGGKWIVSGSEDNLVYIWNL 1065
C +S G + + +G DNLV +W +
Sbjct: 286 CTSLAWSADG-QTLFAGYTDNLVRVWQV 312
Score = 112 bits (281), Expect = 2e-26
Identities = 86/282 (30%), Positives = 141/282 (50%), Gaps = 10/282 (3%)
Frame = +1
Query: 310 LKFTLAGHTKAVSSVKFSPN-GEWLASSSADKLIKIWGAYD-----GKFEKTISGHKLGI 471
L+ TL GH V+ + +P + + S+S DK I +W G ++ + GH +
Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
Query: 472 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 651
SDV SSD +S S D TL++WD+++G + GH+ V F+ + IVSGS D
Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
Query: 652 ESVRIWDVKTGKCLKTL--PAHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDTASGQCL 819
+++++W+ G C T+ +HS+ VS V F N +IVS +D L ++W+ A+ + L
Sbjct: 127 KTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCK-L 184
Query: 820 KTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANF 999
KT ++ V SP+G + D LWD ++GK L T G I
Sbjct: 185 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD-----IINAL 239
Query: 1000 SVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTA 1125
+ ++ + + + IW+L+ K IV +L+ VIST+
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELK---QEVISTS 278
Score = 86.7 bits (213), Expect = 1e-18
Identities = 63/214 (29%), Positives = 100/214 (46%), Gaps = 7/214 (3%)
Frame = +1
Query: 571 TLKGHSNYVFCCNFNPQ-SNLIVSGSFDESVRIW-----DVKTGKCLKTLPAHSDPVSAV 732
TLKGH+ +V PQ ++I+S S D+++ +W + G + L HS VS V
Sbjct: 10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
Query: 733 HFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNT 912
+ DG +S S+DG R+WD +G + + +S V FS + + I++ + D T
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDKT 128
Query: 913 LKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK-WIVSGSEDNLVYIWNLQTKEIVQK 1089
+KLW+ + G C T + ++ FS IVS D LV +WNL ++
Sbjct: 129 IKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTN 187
Query: 1090 LQGHTDVVISTACHPTENIIASAALENDKTIKLW 1191
GHT + + P ++ AS D LW
Sbjct: 188 HIGHTGYLNTVTVSPDGSLCASGG--KDGQAMLW 219
Score = 68.6 bits (166), Expect = 4e-13
Identities = 48/172 (27%), Positives = 80/172 (46%), Gaps = 12/172 (6%)
Frame = +1
Query: 331 HTKAVSSVKFSPNGE--WLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNL 504
H++ VS V+FSPN + S DKL+K+W + K + GH ++ V S D +L
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSL 206
Query: 505 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTG 684
S D +WD++ GK L TL G C F+P + + + S++IWD++ G
Sbjct: 207 CASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC-FSPNRYWLCAAT-GPSIKIWDLE-G 263
Query: 685 KCL----------KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG 810
K + + A +++ ++ DG + + D L R+W G
Sbjct: 264 KIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 315
Score = 47.4 bits (111), Expect = 9e-07
Identities = 32/109 (29%), Positives = 54/109 (49%), Gaps = 5/109 (4%)
Frame = +1
Query: 886 ILAATLDNTLKLWDYSK-----GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLV 1050
IL+A+ D T+ +W ++ G + GH + + + + G++ +SGS D +
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS---SDGQFALSGSWDGTL 87
Query: 1051 YIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS 1197
+W+L T ++ GHT V+S A I S + DKTIKLW +
Sbjct: 88 RLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGS--RDKTIKLWNT 134
Score = 44.7 bits (104), Expect = 6e-06
Identities = 36/137 (26%), Positives = 61/137 (44%), Gaps = 9/137 (6%)
Frame = +1
Query: 301 NYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 480
N LK GHT +++V SP+G AS D +W +GK T+ G + I+ +
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INAL 239
Query: 481 AWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK-------GHSNYVFCCN--FNPQSNLI 633
+S + L +A+ ++KIWD+ + LK + C + ++ +
Sbjct: 240 CFSPNRYWLCAAT-GPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTL 298
Query: 634 VSGSFDESVRIWDVKTG 684
+G D VR+W V G
Sbjct: 299 FAGYTDNLVRVWQVTIG 315
>ref|NP_001012296.1| fizzy/cell division cycle 20 related 1 [Sus scrofa]
Length = 493
Score = 75.9 bits (185), Expect = 2e-15
Identities = 62/249 (24%), Positives = 113/249 (45%), Gaps = 8/249 (3%)
Frame = +1
Query: 469 ISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSF 648
++ V WS NL+ + ++IWD ++GK L L+GH+ V +N ++ + SGS
Sbjct: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN--ADQLSSGSR 289
Query: 649 DESVRIWDVKTG--KCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLK 822
D + D++T + + L H V + ++ D L+ S D +W+ +S ++
Sbjct: 290 DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQ 349
Query: 823 TLIDDDNPPVSFVKFSPNGKYILAA---TLDNTLKLWDYSKG---KCLKTYTGHKNEKYC 984
+ V + +SP+ +LA+ T D ++ W+ G +C+ T + N +
Sbjct: 350 Q-YTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWS 408
Query: 985 IFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAAL 1164
AN V+ G N + +W + V KL GH+ V+ A P I + A
Sbjct: 409 KHANELVS-----THGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGA- 462
Query: 1165 ENDKTIKLW 1191
D+T++ W
Sbjct: 463 -GDETLRFW 470
Score = 71.2 bits (173), Expect = 6e-14
Identities = 64/269 (23%), Positives = 119/269 (44%), Gaps = 12/269 (4%)
Frame = +1
Query: 340 AVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSAS 519
+V+SV +S G +A + ++IW A GK + GH + +AW++D L S S
Sbjct: 231 SVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNADQ--LSSGS 288
Query: 520 DDKTLKIWDVSSG--KCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCL 693
D+ + D+ + + + L+GH V ++ L+ SG D + +W+ + +
Sbjct: 289 RDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPV 348
Query: 694 KTLPAHSDPVSAVHFNRDGSLIVSS---SYDGLCRIWDTASGQCLKTLIDDDNPPVSFVK 864
+ H V A+ ++ +++S + D R W+T +GQ L+ + D V +
Sbjct: 349 QQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCI--DTGSQVCNLA 406
Query: 865 FSPNGKYILA--ATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE 1038
+S + +++ N + +W Y + TGH Y + G+ IV+G+
Sbjct: 407 WSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGH---SYRVLYLAMSPDGEAIVTGAG 463
Query: 1039 DNLVYIWNL-----QTKEIVQKLQGHTDV 1110
D + WN+ TKE V L T +
Sbjct: 464 DETLRFWNVFSKTRSTKESVSVLNLFTRI 492
Score = 67.0 bits (162), Expect = 1e-12
Identities = 57/218 (26%), Positives = 101/218 (46%), Gaps = 8/218 (3%)
Frame = +1
Query: 322 LAGHTKAVSSVKFSPNGEWLASSSADKLI--KIWGAYDGKFEKTISGHKLGISDVAWSSD 495
L GHT V ++ + N + L+S S D++I + + E+ + GH+ + + WS+D
Sbjct: 267 LEGHTARVGALAW--NADQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTD 324
Query: 496 SNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNP-QSNLIVS--GSFDESVRI 666
LL S +D L +W+ SS ++ H V ++P Q L+ S G+ D +R
Sbjct: 325 HQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRF 384
Query: 667 WDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSY-DGLCRIWDTAS-GQCLKTLIDDD 840
W+ TG+ L+ + S + L+ + Y +W S Q K +
Sbjct: 385 WNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAK--LTGH 442
Query: 841 NPPVSFVKFSPNGKYILAATLDNTLKLWD-YSKGKCLK 951
+ V ++ SP+G+ I+ D TL+ W+ +SK + K
Sbjct: 443 SYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK 480
Database: RefSeqSP
Posted date: Aug 1, 2006 7:14 PM
Number of letters in database: 434,620
Number of sequences in database: 1040
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,175,905
Number of Sequences: 1040
Number of extensions: 27847
Number of successful extensions: 158
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 105
length of database: 434,620
effective HSP length: 81
effective length of database: 350,380
effective search space used: 146108460
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqMP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= OVR01_0046_B07
(1498 letters)
Database: RefSeqMP
45,328 sequences; 21,768,885 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_543124.1| WD repeat domain 5 [Mus musculus] 632 0.0
Alignment gi|NP_081389.1| WD repeat domain 5B [Mus musculus] 543 e-154
Alignment gi|NP_038653.1| platelet-activating factor acetylhydrolase, iso... 187 3e-47
Alignment gi|NP_536353.2| F-box and WD-40 domain protein 7, archipelago h... 170 4e-42
Alignment gi|XP_987745.1| PREDICTED: similar to platelet-activating facto... 166 8e-41
Alignment gi|NP_080675.2| mitogen-activated protein kinase organizer 1 [M... 155 8e-38
Alignment gi|NP_081630.1| WD repeat domain 51A [Mus musculus] 154 2e-37
Alignment gi|NP_079921.1| U5 snRNP-specific protein (Prp8-binding) [Mus m... 147 3e-35
Alignment gi|NP_796316.1| TAF5 RNA polymerase II, TATA box binding protei... 146 6e-35
Alignment gi|NP_082016.1| WD repeat domain 51B [Mus musculus] 145 8e-35
>ref|NP_543124.1| WD repeat domain 5 [Mus musculus]
Length = 334
Score = 632 bits (1629), Expect = 0.0
Identities = 304/304 (100%), Positives = 304/304 (100%)
Frame = +1
Query: 292 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI 471
VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI
Sbjct: 31 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI 90
Query: 472 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 651
SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD
Sbjct: 91 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 150
Query: 652 ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLI 831
ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLI
Sbjct: 151 ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLI 210
Query: 832 DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG 1011
DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG
Sbjct: 211 DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG 270
Query: 1012 GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 1191
GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW
Sbjct: 271 GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Query: 1192 KSDC 1203
KSDC
Sbjct: 331 KSDC 334
>ref|NP_081389.1| WD repeat domain 5B [Mus musculus]
Length = 328
Score = 543 bits (1398), Expect = e-154
Identities = 253/303 (83%), Positives = 281/303 (92%)
Frame = +1
Query: 295 KPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGIS 474
KPNYAL+ TLAGH+ A+SSVKFSPNGEWLASS+AD LI IWGAYDG +KT+ GH L IS
Sbjct: 26 KPNYALRLTLAGHSAAISSVKFSPNGEWLASSAADALIIIWGAYDGNCKKTLYGHSLEIS 85
Query: 475 DVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDE 654
DVAWSSDS+ LVSASDDKTLK+WD+ SGKCLKTLKGHS++VFCC+FNP SNLIVSGSFDE
Sbjct: 86 DVAWSSDSSRLVSASDDKTLKVWDMRSGKCLKTLKGHSDFVFCCDFNPPSNLIVSGSFDE 145
Query: 655 SVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID 834
SV+IW+VKTGKCLKTL AHSDP+SAV+FN +GSLIVS SYDGLCRIWD ASGQCL+TL D
Sbjct: 146 SVKIWEVKTGKCLKTLSAHSDPISAVNFNCNGSLIVSGSYDGLCRIWDAASGQCLRTLAD 205
Query: 835 DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG 1014
+ NPPVSFVKFSPNGKYIL ATLDNTLKLWDYS+G+CLKTYTGHKNEKYC+FA+FSVTG
Sbjct: 206 EGNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCLFASFSVTGR 265
Query: 1015 KWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 1194
KW+VSGSEDN+VYIWNLQTKEIVQ+LQGHTDVVIS ACHPT+NIIASAALENDKTIK+W
Sbjct: 266 KWVVSGSEDNMVYIWNLQTKEIVQRLQGHTDVVISAACHPTKNIIASAALENDKTIKVWS 325
Query: 1195 SDC 1203
SDC
Sbjct: 326 SDC 328
>ref|NP_038653.1| platelet-activating factor acetylhydrolase, isoform 1b, beta1 subunit
[Mus musculus]
Length = 410
Score = 187 bits (474), Expect = 3e-47
Identities = 100/313 (31%), Positives = 165/313 (52%), Gaps = 19/313 (6%)
Frame = +1
Query: 313 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS 492
K+ L+GH V+ V F P + S+S D IK+W G FE+T+ GH + D+++
Sbjct: 101 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 160
Query: 493 DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 672
LL S S D T+K+WD +C++T+ GH + V P + IVS S D+++++W+
Sbjct: 161 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
Query: 673 VKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDN--- 843
V+TG C+KT H + V V N+DG+LI S S D R+W A+ +C L + ++
Sbjct: 221 VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 280
Query: 844 -----PPVSFVKFS-----------PNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNE 975
P S+ S G ++L+ + D T+K+WD S G CL T GH N
Sbjct: 281 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW 340
Query: 976 KYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIAS 1155
+ + +GGK+I+S ++D + +W+ + K ++ L H V S H T + +
Sbjct: 341 VRGVLFH---SGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 397
Query: 1156 AALENDKTIKLWK 1194
++ D+T+K+W+
Sbjct: 398 GSV--DQTVKVWE 408
Score = 84.7 bits (208), Expect = 2e-16
Identities = 36/103 (34%), Positives = 62/103 (60%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV 549
G +L S S DK IK+W G T+ GH + V + S ++S +DDKTL++WD
Sbjct: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
Query: 550 SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 678
+ +C+KTL H ++V +F+ + +V+GS D++V++W+ +
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
>ref|NP_536353.2| F-box and WD-40 domain protein 7, archipelago homolog [Mus musculus]
Length = 629
Score = 170 bits (430), Expect = 4e-42
Identities = 96/282 (34%), Positives = 162/282 (57%), Gaps = 8/282 (2%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIW 543
G + S S D +K+W A GK +T+ GH G+ WSS N+++S S D+TLK+W
Sbjct: 313 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVW 368
Query: 544 DVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPV 723
+ +G+C+ TL GH++ V C + + + +VSGS D ++R+WD++TG+CL L H V
Sbjct: 369 NAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAV 426
Query: 724 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATL 903
V + DG +VS +YD + ++WD + CL TL N S ++F +G ++++ +L
Sbjct: 427 RCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYS-LQF--DGIHVVSGSL 481
Query: 904 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG-----KWIVSGSEDNLVYIWNLQ 1068
D ++++WD G C+ T TGH+ S+T G +VSG+ D+ V IW+++
Sbjct: 482 DTSIRVWDVETGNCIHTLTGHQ----------SLTSGMELKDNILVSGNADSTVKIWDIK 531
Query: 1069 TKEIVQKLQGHTDVVISTAC-HPTENIIASAALENDKTIKLW 1191
T + +Q LQG + + C +N + +++ +D T+KLW
Sbjct: 532 TGQCLQTLQGPSKHQSAVTCLQFNKNFVITSS--DDGTVKLW 571
Score = 107 bits (267), Expect = 3e-23
Identities = 56/173 (32%), Positives = 99/173 (57%), Gaps = 3/173 (1%)
Frame = +1
Query: 322 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSN 501
L GH AV V++ +G + S + D ++K+W T+ GH + + + D
Sbjct: 419 LMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGI 474
Query: 502 LLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT 681
+VS S D ++++WDV +G C+ TL GH + + N++VSG+ D +V+IWD+KT
Sbjct: 475 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLT--SGMELKDNILVSGNADSTVKIWDIKT 532
Query: 682 GKCLKTLPA---HSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLI 831
G+CL+TL H V+ + FN+ + +++SS DG ++WD +G+ ++ L+
Sbjct: 533 GQCLQTLQGPSKHQSAVTCLQFNK--NFVITSSDDGTVKLWDLKTGEFIRNLV 583
>ref|XP_987745.1| PREDICTED: similar to platelet-activating factor acetylhydrolase beta
subunit [Mus musculus]
Length = 312
Score = 166 bits (419), Expect = 8e-41
Identities = 88/283 (31%), Positives = 148/283 (52%), Gaps = 19/283 (6%)
Frame = +1
Query: 403 LIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKG 582
L +W G FE+T+ GH + D+++ LL S S D T+K+WD +C++T+ G
Sbjct: 33 LHSVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHG 92
Query: 583 HSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIV 762
H + V P + IVS S D+++++W+V+TG C+KT H + V V N+DG+LI
Sbjct: 93 HDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIA 152
Query: 763 SSSYDGLCRIWDTASGQCLKTLIDDDN--------PPVSFVKFS-----------PNGKY 885
S S D R+W A+ +C L + ++ P S+ S G +
Sbjct: 153 SCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPF 212
Query: 886 ILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNL 1065
+L+ + D T+K+WD S G CL T GH N + + +GGK+I+S ++D + +W+
Sbjct: 213 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFH---SGGKFILSCADDKTLRVWDY 269
Query: 1066 QTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 1194
+ K ++ L H V S H T + + ++ D+T+K+W+
Sbjct: 270 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSV--DQTVKVWE 310
Score = 164 bits (414), Expect = 3e-40
Identities = 94/267 (35%), Positives = 138/267 (51%), Gaps = 20/267 (7%)
Frame = +1
Query: 319 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 498
TL GHT +V + F +G+ LAS SAD IK+W + +T+ GH +S VA +
Sbjct: 47 TLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNG 106
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 678
+ +VSAS DKT+K+W+V +G C+KT GH +V N LI S S D++VR+W V
Sbjct: 107 DHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVA 166
Query: 679 TGKCLKTLPAHSDPVSAVHF--------------------NRDGSLIVSSSYDGLCRIWD 798
T +C L H V + + + G ++S S D ++WD
Sbjct: 167 TKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWD 226
Query: 799 TASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEK 978
++G CL TL+ DN V V F GK+IL+ D TL++WDY +C+KT H E
Sbjct: 227 VSTGMCLMTLVGHDN-WVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAH--EH 283
Query: 979 YCIFANFSVTGGKWIVSGSEDNLVYIW 1059
+ +F T ++V+GS D V +W
Sbjct: 284 FVTSLDFHKT-APYVVTGSVDQTVKVW 309
Score = 84.7 bits (208), Expect = 2e-16
Identities = 36/103 (34%), Positives = 62/103 (60%)
Frame = +1
Query: 370 GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV 549
G +L S S DK IK+W G T+ GH + V + S ++S +DDKTL++WD
Sbjct: 210 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 269
Query: 550 SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 678
+ +C+KTL H ++V +F+ + +V+GS D++V++W+ +
Sbjct: 270 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 312
>ref|NP_080675.2| mitogen-activated protein kinase organizer 1 [Mus musculus]
Length = 315
Score = 155 bits (393), Expect = 8e-38
Identities = 96/289 (33%), Positives = 157/289 (54%), Gaps = 2/289 (0%)
Frame = +1
Query: 340 AVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSAS 519
AV +V+F+ +G + + +DK +K+W G +T SGH + D A S D++ L S
Sbjct: 27 AVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSHLCSGG 86
Query: 520 DDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK--CL 693
DKT+ +WDV++G+ ++ +GH+ V FN ++ +I+SGS D SVR WD ++ K +
Sbjct: 87 GDKTVVLWDVATGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSVRCWDCRSRKPEPV 146
Query: 694 KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSP 873
+TL D +S+V + I++ S DG R +D GQ + P++ FS
Sbjct: 147 QTLDEARDGISSVKVS--DHEILAGSVDGRVRRYDLRMGQVSSDYV---GSPITCTCFSR 201
Query: 874 NGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVY 1053
+G+ L ++LD+TL+L D G+ L Y GHKN++Y + S +VS SED V+
Sbjct: 202 DGQCTLISSLDSTLRLLDKDTGELLGEYVGHKNQQYKLDCCLS-ERDTHVVSCSEDGKVF 260
Query: 1054 IWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSD 1200
W+L + L ++VV S A HPTE + +A +I+ W+ +
Sbjct: 261 FWDLVEGALALALPVGSNVVQSLAYHPTEPCLLTAM---GGSIQYWREE 306
Score = 53.5 bits (127), Expect = 6e-07
Identities = 32/123 (26%), Positives = 58/123 (47%)
Frame = +1
Query: 559 KCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 738
K +KTL V FN N ++ D+++++W+ G L+T H V
Sbjct: 16 KRMKTLDCSQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAG 75
Query: 739 NRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLK 918
+ D S + S D +WD A+GQ ++ V+ V+F+ IL+ ++D++++
Sbjct: 76 SFDNSHLCSGGGDKTVVLWDVATGQVVRKFRGHAG-KVNTVQFNEEATVILSGSIDSSVR 134
Query: 919 LWD 927
WD
Sbjct: 135 CWD 137
>ref|NP_081630.1| WD repeat domain 51A [Mus musculus]
Length = 405
Score = 154 bits (389), Expect = 2e-37
Identities = 90/252 (35%), Positives = 140/252 (55%), Gaps = 1/252 (0%)
Frame = +1
Query: 307 ALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTI-SGHKLGISDVA 483
A +FT GH AV+ V FSP+G LAS S DK ++IW + K E T+ H + V
Sbjct: 54 AYRFT--GHKDAVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVH 110
Query: 484 WSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVR 663
+ SD LV+ASDDKT+K+W + L +L H N+V C F+P LIVS S D++V+
Sbjct: 111 FCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVK 170
Query: 664 IWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDN 843
+WD + +C+ + H V+ V F+ G+ I ++ D ++WD + + L+ +
Sbjct: 171 LWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQH-YQLHS 229
Query: 844 PPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWI 1023
V+ + F P+G Y++ A+ D+TLK+ D +G+ L T GH+ + FS T G++
Sbjct: 230 AAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTV--AFSRT-GEYF 286
Query: 1024 VSGSEDNLVYIW 1059
SG D V +W
Sbjct: 287 ASGGSDEQVMVW 298
Score = 140 bits (353), Expect = 4e-33
Identities = 83/254 (32%), Positives = 135/254 (53%)
Frame = +1
Query: 427 DGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCC 606
D E+ GH+ ++ V +S ++ L S S D TL IW + S GH + V C
Sbjct: 8 DPSLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCV 67
Query: 607 NFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC 786
NF+P +L+ SGS D++VRIW AH+ V +VHF DG +V++S D
Sbjct: 68 NFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTV 127
Query: 787 RIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGH 966
++W T + L +L N V KFSP+G+ I++A+ D T+KLWD + +C+ +Y H
Sbjct: 128 KVWSTHRQRFLFSLTQHIN-WVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEH 186
Query: 967 KNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENI 1146
+ + +F G I + DN V +W+ +T ++Q Q H+ V + + HP+ N
Sbjct: 187 GG--FVTYVDFH-PSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNY 243
Query: 1147 IASAALENDKTIKL 1188
+ +A+ +D T+K+
Sbjct: 244 LITAS--SDSTLKI 255
Score = 137 bits (345), Expect = 3e-32
Identities = 88/291 (30%), Positives = 144/291 (49%)
Frame = +1
Query: 328 GHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLL 507
GH AV+ V FS N + LAS S D + IW +GHK ++ V +S +LL
Sbjct: 17 GHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLL 76
Query: 508 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 687
S S DKT++IW + + H+ V +F +V+ S D++V++W +
Sbjct: 77 ASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQR 136
Query: 688 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKF 867
L +L H + V F+ DG LIVS+S D ++WD S +C+ + + V++V F
Sbjct: 137 FLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGG-FVTYVDF 195
Query: 868 SPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNL 1047
P+G I AA +DNT+K+WD + L+ Y H + + S G ++++ S D+
Sbjct: 196 HPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPS---GNYLITASSDST 252
Query: 1048 VYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSD 1200
+ I +L ++ L GH + A T AS +D+ + +WKS+
Sbjct: 253 LKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGG--SDEQVMVWKSN 301
>ref|NP_079921.1| U5 snRNP-specific protein (Prp8-binding) [Mus musculus]
Length = 370
Score = 147 bits (371), Expect = 3e-35
Identities = 88/261 (33%), Positives = 143/261 (54%), Gaps = 10/261 (3%)
Frame = +1
Query: 322 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAY-DGKFEKTISGHKLGISDVAWSSDS 498
L+GH V KF PNG LAS+ D+LI +W Y D T+ GH + ++ +++D
Sbjct: 63 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 122
Query: 499 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCC---NFNPQSNLIVSGSFDESVRIW 669
++L SAS DKT+ +WD +G+ +K LKGH+++V C PQ L+ +GS D +V++W
Sbjct: 123 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQ--LVCTGSDDGTVKLW 180
Query: 670 DVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 849
D++ ++T ++ V AV FN I+S D ++WD + T+ +
Sbjct: 181 DIRKRAAVQTF-QNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD-S 238
Query: 850 VSFVKFSPNGKYILAATLDNTLKLWDY----SKGKCLKTYTG--HKNEKYCIFANFSVTG 1011
V+ + S G Y+L+ +DNT+++WD K +C+K + G H EK + ++S G
Sbjct: 239 VTDLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDG 298
Query: 1012 GKWIVSGSEDNLVYIWNLQTK 1074
K I +GS D VY+W Q +
Sbjct: 299 SK-IAAGSADRFVYVWTPQAE 318
Score = 109 bits (272), Expect = 9e-24
Identities = 61/208 (29%), Positives = 107/208 (51%), Gaps = 2/208 (0%)
Frame = +1
Query: 574 LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKC--LKTLPAHSDPVSAVHFNRD 747
L GH V+CC F+P + + S FD + +W+V G C TL HS V +H+N D
Sbjct: 63 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNV-YGDCDNYATLKGHSGAVMELHYNTD 121
Query: 748 GSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWD 927
GS++ S+S D +WD+ +G+ +K L + S + + + D T+KLWD
Sbjct: 122 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 181
Query: 928 YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTD 1107
K ++T+ +N + F+ T + I+SG DN + +W+L+ ++ ++GH D
Sbjct: 182 IRKRAAVQTF---QNTYQVLAVTFNDTSDQ-IISGGIDNDIKVWDLRQNKLTYTMRGHAD 237
Query: 1108 VVISTACHPTENIIASAALENDKTIKLW 1191
V + + + S A++N T+++W
Sbjct: 238 SVTDLSLSSEGSYLLSNAMDN--TVRVW 263
>ref|NP_796316.1| TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated
factor, 100kDa [Mus musculus]
Length = 801
Score = 146 bits (368), Expect = 6e-35
Identities = 86/292 (29%), Positives = 147/292 (50%)
Frame = +1
Query: 316 FTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD 495
+T + +++V + + +A AD +++W K + V +SD
Sbjct: 465 YTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKK-----------LRSVKQASD 513
Query: 496 SNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 675
+L+ SDD +I D + LK L GHS V+ +F+P N ++S S D +VR+W +
Sbjct: 514 LSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL 573
Query: 676 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVS 855
+T CL H+ PV F+ G VS +D + R+W T Q L+ + V+
Sbjct: 574 QTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLR-IFAGHLADVN 632
Query: 856 FVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGS 1035
+F PN Y+ + D T++LWD G C++ +TGHK + + FS G+++ +G+
Sbjct: 633 CTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSL--TFS-PNGRFLATGA 689
Query: 1036 EDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 1191
D V +W++ +V +L+GHTD V S I+AS +++N T++LW
Sbjct: 690 TDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDN--TVRLW 739
Score = 122 bits (305), Expect = 1e-27
Identities = 66/223 (29%), Positives = 106/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 322 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSN 501
L GH+ V FSP+ +L SSS D +++W GH + D +S
Sbjct: 540 LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 599
Query: 502 LLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT 681
VS D+ ++W + L+ GH V C F+P SN + +GS D +VR+WDV
Sbjct: 600 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 659
Query: 682 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFV 861
G C++ H P+ ++ F+ +G + + + DG +WD G + L V +
Sbjct: 660 GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGEL-KGHTDTVCSL 718
Query: 862 KFSPNGKYILAATLDNTLKLWDYSKG------KCLKTYTGHKN 972
+FS +G+ + + ++DNT++LWD K T TGH N
Sbjct: 719 RFSRDGEILASGSMDNTVRLWDAVKAFEDLETDDFTTATGHIN 761
Score = 115 bits (289), Expect = 9e-26
Identities = 68/242 (28%), Positives = 115/242 (47%)
Frame = +1
Query: 337 KAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSA 516
K + SVK + + + S D L +I K + GH + ++S D N L+S+
Sbjct: 503 KKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSS 562
Query: 517 SDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLK 696
S+D T+++W + + CL KGH+ V+ F+P VSG D R+W + L+
Sbjct: 563 SEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLR 622
Query: 697 TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 876
H V+ F+ + + + + S D R+WD +G C++ + P+ + FSPN
Sbjct: 623 IFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVR-IFTGHKGPIHSLTFSPN 681
Query: 877 GKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYI 1056
G+++ D + LWD G + GH + + FS G+ + SGS DN V +
Sbjct: 682 GRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSL--RFS-RDGEILASGSMDNTVRL 738
Query: 1057 WN 1062
W+
Sbjct: 739 WD 740
Score = 109 bits (273), Expect = 7e-24
Identities = 53/192 (27%), Positives = 95/192 (49%), Gaps = 1/192 (0%)
Frame = +1
Query: 328 GHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLL 507
GH V +FSP G + S D++ ++W + + +GH ++ + +SN +
Sbjct: 584 GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYV 643
Query: 508 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 687
+ S D+T+++WDV +G C++ GH + F+P + +G+ D V +WD+ G
Sbjct: 644 ATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGL 703
Query: 688 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG-QCLKTLIDDDNPPVSFVK 864
+ L H+D V ++ F+RDG ++ S S D R+WD + L+T DD +
Sbjct: 704 MVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAVKAFEDLET--DDFTTATGHIN 761
Query: 865 FSPNGKYILAAT 900
N + +L T
Sbjct: 762 LPENSQELLLGT 773
Score = 89.7 bits (221), Expect = 7e-18
Identities = 50/174 (28%), Positives = 86/174 (49%), Gaps = 24/174 (13%)
Frame = +1
Query: 325 AGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNL 504
AGH V+ +F PN ++A+ SAD+ +++W +G + +GHK I + +S +
Sbjct: 625 AGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRF 684
Query: 505 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD-VKT 681
L + + D + +WD+ G + LKGH++ V F+ ++ SGS D +VR+WD VK
Sbjct: 685 LATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAVKA 744
Query: 682 GKCLKT-----------LPAHSD------------PVSAVHFNRDGSLIVSSSY 774
+ L+T LP +S PV +HF R ++ + +Y
Sbjct: 745 FEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAY 798
Score = 68.2 bits (165), Expect = 2e-11
Identities = 50/198 (25%), Positives = 79/198 (39%), Gaps = 30/198 (15%)
Frame = +1
Query: 688 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW-------------------DTASG 810
C T ++AV D SLI D R+W D S
Sbjct: 463 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESD 522
Query: 811 QCLKTLIDD-----------DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTY 957
L+ ++D+ + PV FSP+ Y+L+++ D T++LW CL Y
Sbjct: 523 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGY 582
Query: 958 TGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPT 1137
GH Y ++ G + VSG D + +W + ++ GH V T HP
Sbjct: 583 KGH---NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPN 639
Query: 1138 ENIIASAALENDKTIKLW 1191
N +A+ + D+T++LW
Sbjct: 640 SNYVATGSA--DRTVRLW 655
>ref|NP_082016.1| WD repeat domain 51B [Mus musculus]
Length = 476
Score = 145 bits (367), Expect = 8e-35
Identities = 89/297 (29%), Positives = 149/297 (50%)
Frame = +1
Query: 310 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWS 489
L+ + GH A++S FSPN + +A++S D + +W GHK ++ + +S
Sbjct: 10 LERSFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFS 69
Query: 490 SDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 669
NLL SAS D+T+++W + K H+ V +F+ L+V+ S D+S+++W
Sbjct: 70 PQGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVW 129
Query: 670 DVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 849
+ + L +L H+ V F+ DG LIVS S D +IWDT + QC+ D
Sbjct: 130 SMFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNN-FSDSVGF 188
Query: 850 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVS 1029
+FV F+PNG I +A D+ +K+WD K L+ Y H C+ +F G +V+
Sbjct: 189 ANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCL--SFHPLGNS-LVT 245
Query: 1030 GSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSD 1200
S D V + +L ++ LQGHT V + + ++ S D + +W+++
Sbjct: 246 ASSDGTVKMLDLIEGRLIYTLQGHTGPVFTVSFSKDGELLTSGGA--DAQVLIWRTN 300
Score = 138 bits (348), Expect = 1e-32
Identities = 80/256 (31%), Positives = 135/256 (52%)
Frame = +1
Query: 292 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI 471
+KP +A + GH V+S++FSP G LAS+S D+ +++W H +
Sbjct: 47 LKP-HARAYRYVGHKDVVTSLQFSPQGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPV 105
Query: 472 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 651
V +S+D LLV+AS+DK++K+W + + L +L H+++V C F+P LIVS S D
Sbjct: 106 RSVDFSADGQLLVTASEDKSIKVWSMFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSED 165
Query: 652 ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLI 831
++++IWD +C+ + V FN +G+ I S+ D +IWD + L+
Sbjct: 166 KTIKIWDTTNKQCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQH-Y 224
Query: 832 DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG 1011
+ V+ + F P G ++ A+ D T+K+ D +G+ + T GH + + +FS
Sbjct: 225 QVHSCGVNCLSFHPLGNSLVTASSDGTVKMLDLIEGRLIYTLQGHTGPVFTV--SFS-KD 281
Query: 1012 GKWIVSGSEDNLVYIW 1059
G+ + SG D V IW
Sbjct: 282 GELLTSGGADAQVLIW 297
Score = 124 bits (312), Expect = 2e-28
Identities = 75/257 (29%), Positives = 132/257 (51%)
Frame = +1
Query: 418 GAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYV 597
G D E++ GHK I+ +S + + +AS D L +W + GH + V
Sbjct: 4 GLEDPILERSFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVV 63
Query: 598 FCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYD 777
F+PQ NL+ S S D +VR+W + AH+ PV +V F+ DG L+V++S D
Sbjct: 64 TSLQFSPQGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASED 123
Query: 778 GLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTY 957
++W + L +L + V KFSP+G+ I++ + D T+K+WD + +C+ +
Sbjct: 124 KSIKVWSMFRQRFLYSLYRHTH-WVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNF 182
Query: 958 TGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPT 1137
+ + + F +F+ G I S D+ V IW+++ +++Q Q H+ V + HP
Sbjct: 183 S--DSVGFANFVDFN-PNGTCIASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSFHPL 239
Query: 1138 ENIIASAALENDKTIKL 1188
N + +A+ +D T+K+
Sbjct: 240 GNSLVTAS--SDGTVKM 254
Database: RefSeqMP
Posted date: Aug 2, 2006 12:58 AM
Number of letters in database: 21,768,885
Number of sequences in database: 45,328
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,072,696
Number of Sequences: 45328
Number of extensions: 1466399
Number of successful extensions: 10633
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 5357
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8102
length of database: 21,768,885
effective HSP length: 108
effective length of database: 16,873,461
effective search space used: 6580649790
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)