Search to RefSeqBP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= OVRM1_0206_H07
(1544 letters)
Database: RefSeqBP
33,508 sequences; 16,112,626 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|XP_582319.2| PREDICTED: similar to retinol dehydrogenase 14 ... 563 e-160
Alignment gi|NP_899207.1| double substrate-specificity short chain dehydr... 245 8e-65
Alignment gi|XP_592820.2| PREDICTED: similar to retinol dehydrogenase 11 ... 213 3e-55
Alignment gi|XP_870721.1| PREDICTED: similar to Retinol dehydrogenase 11 ... 183 3e-46
Alignment gi|XP_582373.2| PREDICTED: similar to Retinol dehydrogenase 11 ... 179 4e-45
Alignment gi|XP_584642.2| PREDICTED: similar to retinol dehydrogenase 11 ... 157 2e-38
Alignment gi|XP_584810.2| PREDICTED: similar to retinol dehydrogenase 13 ... 141 2e-33
Alignment gi|XP_591168.2| PREDICTED: similar to dehydrogenase/reductase (... 139 5e-33
Alignment gi|XP_584629.2| PREDICTED: similar to Retinol dehydrogenase 13,... 104 2e-22
Alignment gi|XP_583859.2| PREDICTED: similar to short chain dehydrogenase... 98 2e-20
>ref|XP_582319.2| PREDICTED: similar to retinol dehydrogenase 14 (all-trans and 9-cis)
[Bos taurus]
Length = 420
Score = 563 bits (1452), Expect = e-160
Identities = 291/364 (79%), Positives = 302/364 (82%)
Frame = +1
Query: 1 VQVAALAPGARRLRKSCEGDGGPSXXXXXXXXXXXXXXXXXXXXXXXXXRRFVGPSVQRL 180
VQVA PG R RKS G GGPS RRFVG SVQRL
Sbjct: 57 VQVAGFGPGKPRPRKSRAGAGGPSAPVAMAVGTAAALLAALGGILWLAARRFVGSSVQRL 116
Query: 181 HRGGDSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELR 360
H+G DSGLM GKTVLITGANSGLGRATAAELLRLGARVIMGCRDR RAEEAAGQLRRE+
Sbjct: 117 HQGRDSGLMRGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRERAEEAAGQLRREVC 176
Query: 361 QTEGPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMK 540
GP+ GPNSGGAGELVV+ELDLASL SVR+FCQEMLQEEPRLDVLINNAG+FQCPYMK
Sbjct: 177 PAGGPDSGPNSGGAGELVVKELDLASLSSVRSFCQEMLQEEPRLDVLINNAGVFQCPYMK 236
Query: 541 TEDGFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYN 720
TEDGFEMQF V KSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYN
Sbjct: 237 TEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYN 296
Query: 721 KSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVS 900
KSFCYSRSKLANILFTRELARRLEGT+VTVNVLHPGIVRTNLGRHIHIPLLV+PLFNLVS
Sbjct: 297 KSFCYSRSKLANILFTRELARRLEGTSVTVNVLHPGIVRTNLGRHIHIPLLVRPLFNLVS 356
Query: 901 WAFFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMV 1080
WAFFKTP EGAQT+VYLASSPEVEGVSG+YFGDCKEEELLPKAMD+SVARKLWDISEVMV
Sbjct: 357 WAFFKTPEEGAQTAVYLASSPEVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMV 416
Query: 1081 GILK 1092
GILK
Sbjct: 417 GILK 420
>ref|NP_899207.1| double substrate-specificity short chain dehydrogenase/reductase 2
[Bos taurus]
Length = 316
Score = 245 bits (625), Expect = 8e-65
Identities = 133/313 (42%), Positives = 190/313 (60%), Gaps = 3/313 (0%)
Frame = +1
Query: 157 VGPSVQRLHRGG---DSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAE 327
+ PS+++ GG + GK V+ITGAN+G+G+ TA EL R GARV + CRD + E
Sbjct: 18 IAPSIRKFFAGGVCRTDVQLFGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGE 77
Query: 328 EAAGQLRRELRQTEGPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLIN 507
AA +++ + + ++ ++VR+LDL+ +S+RAF + L EE +L +LIN
Sbjct: 78 SAASEIQADTKNSQ-------------VLVRKLDLSDTKSIRAFAEGFLAEEKQLHILIN 124
Query: 508 NAGIFQCPYMKTEDGFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDIN 687
NAG+ CPY KT DGFE AV K SAP+R+V +SS + G I
Sbjct: 125 NAGVMLCPYSKTADGFETHLAVNHLGHFLLTHLLLGRLKESAPARVVNLSSVAHHLGKIR 184
Query: 688 FEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIP 867
F DL ++ YN F Y SKLAN+LFTRELA+RL+GT VT +HPGIVR+ L RH +
Sbjct: 185 FHDLQGDKYYNLGFAYCHSKLANVLFTRELAKRLKGTGVTTYAVHPGIVRSKLVRHSFLL 244
Query: 868 LLVKPLFNLVSWAFFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVA 1047
L+ LF+ F KT EGAQTS++ A + +E +SGKYF DCK+ + P+A ++ A
Sbjct: 245 CLLWRLFS----PFLKTTWEGAQTSLHCALAEGLEPLSGKYFSDCKKTWVSPRARNNKTA 300
Query: 1048 RKLWDISEVMVGI 1086
+LW++S ++GI
Sbjct: 301 ERLWNVSCELLGI 313
>ref|XP_592820.2| PREDICTED: similar to retinol dehydrogenase 11 (predicted) [Bos
taurus]
Length = 377
Score = 213 bits (542), Expect = 3e-55
Identities = 123/296 (41%), Positives = 167/296 (56%), Gaps = 2/296 (0%)
Frame = +1
Query: 205 MHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEG 384
+ G+T ++TGANSG+G+ TA EL R GARV++ CR R R E AA LR+E
Sbjct: 34 LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQE---------- 83
Query: 385 PNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQ 564
G E++ LDLASL SVRAF L EPRLD+LI+NAGI C +T + F +
Sbjct: 84 ---SGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCG--RTREPFNLL 138
Query: 565 FAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLNSEQS--YNKSFCYS 738
V K+SAPSR+VVVSS ++ G ++F L+ + Y+
Sbjct: 139 LRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRRGRLDFTRLDHPVVGWQQELRAYA 198
Query: 739 RSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKT 918
SKLAN+LF RELA +LEGT VT HPG V + L H+P ++PL ++W +
Sbjct: 199 NSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLR-HVPGWLRPLLRPLAWLVLRA 257
Query: 919 PAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGI 1086
P GAQT +Y A +E +SG+YF +C EE+ P A DD A +LW+ S + G+
Sbjct: 258 PRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGL 313
>ref|XP_870721.1| PREDICTED: similar to Retinol dehydrogenase 11 (Retinal reductase 1)
(RalR1) (Prostate short-chain dehydrogenase/reductase 1)
(Androgen-regulated short-chain dehydrogenase/reductase
1) (HCV core-binding protein HCBP12) isoform 2 [Bos
taurus]
Length = 314
Score = 183 bits (465), Expect = 3e-46
Identities = 108/292 (36%), Positives = 164/292 (56%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
GK ++TGAN+G+G+ TA EL R GARV + CRD E A RE++ G ++
Sbjct: 15 GKVAVVTGANAGIGKETAKELARRGARVYLACRDVQNGELVA----REIQMMTGNQQ--- 67
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
++VR+LDLA +S+RAF + L++ + ++ ++ C + + G +
Sbjct: 68 ------VLVRKLDLADTKSIRAFAKRFLEDHKYIHLINSSPHFLICGFPGSSAGKDSACN 121
Query: 571 VXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSRSKL 750
+ SAPSR+V VSS + G I+F +L E+ Y Y SKL
Sbjct: 122 TGYLGHFLLTHLLLEKLEESAPSRVVNVSSLAHLLGRIHFHNLQGEKFYQSGLAYCHSKL 181
Query: 751 ANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPAEG 930
ANILFT+ELARRL+G+ VTV +HPG V + L RH + + +F+ F KTP +G
Sbjct: 182 ANILFTQELARRLKGSGVTVYSVHPGTVNSELVRHSALMRWIWWIFSF----FIKTPQQG 237
Query: 931 AQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGI 1086
AQTS+Y A + +E +SG +F DC + +A +++VAR+LWD+S ++GI
Sbjct: 238 AQTSLYCALTEGLEVLSGNHFSDCHVAWVSAQARNETVARRLWDVSCDLLGI 289
>ref|XP_582373.2| PREDICTED: similar to Retinol dehydrogenase 11 (Retinal reductase 1)
(RalR1) (Prostate short-chain dehydrogenase/reductase 1)
(Androgen-regulated short-chain dehydrogenase/reductase
1) (HCV core-binding protein HCBP12) isoform 1 [Bos
taurus]
Length = 308
Score = 179 bits (455), Expect = 4e-45
Identities = 111/292 (38%), Positives = 164/292 (56%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
GK ++TGAN+G+G+ TA EL R GARV + CRD E A RE++ G ++
Sbjct: 15 GKVAVVTGANAGIGKETAKELARRGARVYLACRDVQNGELVA----REIQMMTGNQQ--- 67
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
++VR+LDLA +S+RAF + L++ + LIN+ G + + G +
Sbjct: 68 ------VLVRKLDLADTKSIRAFAKRFLEDHKYIH-LINSVG-----FPGSSAGKDSACN 115
Query: 571 VXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSRSKL 750
+ SAPSR+V VSS + G I+F +L E+ Y Y SKL
Sbjct: 116 TGYLGHFLLTHLLLEKLEESAPSRVVNVSSLAHLLGRIHFHNLQGEKFYQSGLAYCHSKL 175
Query: 751 ANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPAEG 930
ANILFT+ELARRL+G+ VTV +HPG V + L RH + + +F+ F KTP +G
Sbjct: 176 ANILFTQELARRLKGSGVTVYSVHPGTVNSELVRHSALMRWIWWIFSF----FIKTPQQG 231
Query: 931 AQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGI 1086
AQTS+Y A + +E +SG +F DC + +A +++VAR+LWD+S ++GI
Sbjct: 232 AQTSLYCALTEGLEVLSGNHFSDCHVAWVSAQARNETVARRLWDVSCDLLGI 283
>ref|XP_584642.2| PREDICTED: similar to retinol dehydrogenase 11 (predicted) [Bos
taurus]
Length = 330
Score = 157 bits (397), Expect = 2e-38
Identities = 101/290 (34%), Positives = 161/290 (55%), Gaps = 4/290 (1%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
GKT ++TGANSG+G+A + EL GARVI+ CR R R ++A +++ +
Sbjct: 49 GKTAVVTGANSGIGKAVSQELAHRGARVILACRSRERGQQALAEIQATSK---------- 98
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
+ L++ E+DL+S+ S+R+F Q +LQE P + +L+NNA + P T +G ++ FA
Sbjct: 99 ---SNRLLLGEVDLSSMASIRSFAQRLLQECPEIHLLVNNAAVCGFPTTLTPEGLDLTFA 155
Query: 571 VXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDL---NSEQSYNKSFCYSR 741
+ + +R+V VSS +G I+ + L ++N++ Y
Sbjct: 156 TNYTGPFLLTNLLQGALQRAGSARVVNVSSFRQSHGYIDEDHLIGAGRPLTFNQN--YDC 213
Query: 742 SKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTP 921
SKL FT +LA+RL+GT VTVN + PG+V T + + H + LF L+S+ FFK
Sbjct: 214 SKLLLASFTGKLAQRLQGTGVTVNSVDPGVVYTKIMK--HFSWSYRFLFWLLSF-FFKDS 270
Query: 922 AEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPK-AMDDSVARKLWDIS 1068
+GA +YL+ + E++G+SGK+F L P+ A D VA+ LW+ S
Sbjct: 271 KQGAVPVLYLSLAKELDGISGKHFSSSCVITLPPEAAQDPHVAQSLWNTS 320
>ref|XP_584810.2| PREDICTED: similar to retinol dehydrogenase 13 (all-trans and 9-cis)
[Bos taurus]
Length = 223
Score = 141 bits (355), Expect = 2e-33
Identities = 79/158 (50%), Positives = 104/158 (65%), Gaps = 3/158 (1%)
Frame = +1
Query: 622 KSSAPSRIVVVSSKLYKYGDINFEDLNSEQ-SYNKSFCYSRSKLANILFTRELARRLEGT 798
K+SAPSRI+ VSS + G I+FEDLN E+ Y+ Y +SKLA ++ T+EL+RRL+GT
Sbjct: 50 KASAPSRIINVSSLAHVAGHIDFEDLNWEKRKYDTKAAYCQSKLAVVVSTKELSRRLQGT 109
Query: 799 NVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNL--VSWAFFKTPAEGAQTSVYLASSPEVE 972
VTVN LHPG+ RT LGRH + F L + W K+P AQ SVYLA + E+E
Sbjct: 110 GVTVNALHPGVARTELGRHTGMHSSAFSSFTLGPIFWLLVKSPELAAQPSVYLAVAEELE 169
Query: 973 GVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGI 1086
GVSGKYF KE+ P+A D+ VA++LW S +VG+
Sbjct: 170 GVSGKYFDVLKEKPPAPEAEDEEVAKRLWAESVRLVGL 207
>ref|XP_591168.2| PREDICTED: similar to dehydrogenase/reductase (SDR family) X-linked
[Bos taurus]
Length = 251
Score = 139 bits (351), Expect = 5e-33
Identities = 91/227 (40%), Positives = 123/227 (54%), Gaps = 7/227 (3%)
Frame = +1
Query: 427 DLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFAVXXXXXXXXXXX 606
DLAS+RS+R F Q ++ L VL+NNAG+ P TEDGFE F V
Sbjct: 11 DLASMRSIREFVQTFKMKKLPLHVLVNNAGVMMVPQRTTEDGFEEHFGVNYLGHFLLTNL 70
Query: 607 XXXXXKSS-AP---SRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSRSKLANILFTRE 774
+ S AP +R+V VSS + G++N +DL S Y+ Y++SKLA +LFT
Sbjct: 71 LLDTLQESGAPGHSARVVTVSSATHYVGELNLDDLQSSTYYSAHAAYAQSKLALVLFTYH 130
Query: 775 LARRL--EGTNVTVNVLHPGIVRTNLGRHIHIPL-LVKPLFNLVSWAFFKTPAEGAQTSV 945
L L +G VT +V PG+V T+L R++ LVK L+ W FKTP EGA TSV
Sbjct: 131 LQALLTAQGMPVTASVADPGVVDTDLYRYVFWGTRLVK---KLLGWWVFKTPDEGAWTSV 187
Query: 946 YLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGI 1086
Y A +P +EG+ G+Y + KE L D + R+LW S + GI
Sbjct: 188 YAAVTPALEGLGGRYLYNEKETRSLEATYDPELQRQLWARSCQLTGI 234
>ref|XP_584629.2| PREDICTED: similar to Retinol dehydrogenase 13, partial [Bos
taurus]
Length = 148
Score = 104 bits (259), Expect = 2e-22
Identities = 52/121 (42%), Positives = 74/121 (61%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
GKTV++TGAN+G+G+ TA EL + G +I+ CRD + E AA ++R E
Sbjct: 38 GKTVIVTGANTGIGKQTALELAKRGGNIILACRDMEKCEAAAKEIRGETLNHR------- 90
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
+ R LDLASL+S+R F ++ +EE + +LINNA + +CP+ TEDGFEMQ
Sbjct: 91 ------VNARHLDLASLKSIREFAAKVTEEEEHVHILINNAAVMRCPHWTTEDGFEMQLG 144
Query: 571 V 573
V
Sbjct: 145 V 145
>ref|XP_583859.2| PREDICTED: similar to short chain dehydrogenase/reductase [Bos
taurus]
Length = 317
Score = 98.2 bits (243), Expect = 2e-20
Identities = 80/267 (29%), Positives = 124/267 (46%), Gaps = 2/267 (0%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
G+ ++TG NSG+G+ATA E+ + G V + CRD +RAE A ++ RE
Sbjct: 40 GRAFMVTGGNSGIGKATAMEIAKRGGTVHLVCRDHSRAEGAKAEIIRE------------ 87
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
G + + +DL+ +SV F + QE L+VLINNAG TEDG E FA
Sbjct: 88 -SGNQNIFLHIVDLSLPKSVWKFVENFKQEH-TLNVLINNAGCMVNKRELTEDGLEKNFA 145
Query: 571 VXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLNSEQ-SYNKSFCYSRSK 747
+ R++ VSS +N +D SE+ +++ + Y+++K
Sbjct: 146 TNTLGVYVLTTALIPVLEKEHDPRVITVSSGGMLVQKLNTDDPQSERTAFDGTMVYAQNK 205
Query: 748 LANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPAE 927
++ T AR + + +HPG V T R L P F+ A ++ A+
Sbjct: 206 RQQVVLTERWARAHPA--IHFSCMHPGWVDTPGVR------LSMPGFHARLGARLRSEAQ 257
Query: 928 GAQTSVYLASSPEVEG-VSGKYFGDCK 1005
GA T ++LA +P SG +F D K
Sbjct: 258 GADTVLWLALAPAATAQPSGCFFQDRK 284
Database: RefSeqBP
Posted date: Aug 1, 2006 7:14 PM
Number of letters in database: 16,112,626
Number of sequences in database: 33,508
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,156,077
Number of Sequences: 33508
Number of extensions: 1057341
Number of successful extensions: 3622
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 3170
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3556
length of database: 16,112,626
effective HSP length: 106
effective length of database: 12,560,778
effective search space used: 5124797424
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqCP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= OVRM1_0206_H07
(1544 letters)
Database: RefSeqCP
33,732 sequences; 19,266,565 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|XP_540096.2| PREDICTED: similar to retinol dehydrogenase 14 ... 550 e-156
Alignment gi|XP_857582.1| PREDICTED: similar to retinol dehydrogenase 14 ... 474 e-133
Alignment gi|XP_547866.2| PREDICTED: similar to retinol dehydrogenase 12 ... 239 7e-63
Alignment gi|XP_854127.1| PREDICTED: similar to Retinol dehydrogenase 13 ... 237 3e-62
Alignment gi|XP_854354.1| PREDICTED: similar to Retinol dehydrogenase 11 ... 227 3e-59
Alignment gi|XP_548293.2| PREDICTED: similar to retinol dehydrogenase 11 ... 207 2e-53
Alignment gi|XP_857503.1| PREDICTED: similar to retinol dehydrogenase 14 ... 187 2e-47
Alignment gi|XP_852222.1| PREDICTED: similar to dehydrogenase/reductase (... 168 2e-41
Alignment gi|XP_533000.2| PREDICTED: similar to Retinol dehydrogenase 12 ... 153 4e-37
Alignment gi|XP_852623.1| PREDICTED: similar to WW domain-containing oxid... 125 9e-29
>ref|XP_540096.2| PREDICTED: similar to retinol dehydrogenase 14 (all-trans and 9-cis)
isoform 1 [Canis familiaris]
Length = 336
Score = 550 bits (1417), Expect = e-156
Identities = 281/315 (89%), Positives = 287/315 (91%)
Frame = +1
Query: 148 RRFVGPSVQRLHRGGDSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAE 327
RRFVGP VQ+LH GGDSGLMHGKTVLITGANSGLGRATAA LLRLGARVIMGCRDRARAE
Sbjct: 22 RRFVGPGVQQLHGGGDSGLMHGKTVLITGANSGLGRATAAALLRLGARVIMGCRDRARAE 81
Query: 328 EAAGQLRRELRQTEGPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLIN 507
EAAGQLRRELRQ G E G + G AGELVVRELDLASLRSVRAFCQE+LQEEPRLDVLIN
Sbjct: 82 EAAGQLRRELRQAGGREPGSDVGAAGELVVRELDLASLRSVRAFCQEVLQEEPRLDVLIN 141
Query: 508 NAGIFQCPYMKTEDGFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDIN 687
NAGIFQCPYMKTEDGFEMQF V K+SAPSRIVVVSSKLYKYGDIN
Sbjct: 142 NAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKNSAPSRIVVVSSKLYKYGDIN 201
Query: 688 FEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIP 867
FEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIP
Sbjct: 202 FEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIP 261
Query: 868 LLVKPLFNLVSWAFFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVA 1047
LLV+PLFNLVSWAFFKTP EGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMD+SVA
Sbjct: 262 LLVRPLFNLVSWAFFKTPVEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDESVA 321
Query: 1048 RKLWDISEVMVGILK 1092
RKLWDISEVMVGILK
Sbjct: 322 RKLWDISEVMVGILK 336
>ref|XP_857582.1| PREDICTED: similar to retinol dehydrogenase 14 (all-trans and 9-cis)
isoform 4 [Canis familiaris]
Length = 307
Score = 474 bits (1220), Expect = e-133
Identities = 252/315 (80%), Positives = 258/315 (81%)
Frame = +1
Query: 148 RRFVGPSVQRLHRGGDSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAE 327
RRFVGP VQ+LH GGDSGLMHGKTVLITGANSGLGRATAA LLRLGARVIMGCRDRARAE
Sbjct: 22 RRFVGPGVQQLHGGGDSGLMHGKTVLITGANSGLGRATAAALLRLGARVIMGCRDRARAE 81
Query: 328 EAAGQLRRELRQTEGPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLIN 507
EAAGQLRRELRQ G E G + G AGELVVRELDLASLRSVRAFCQE+LQ
Sbjct: 82 EAAGQLRRELRQAGGREPGSDVGAAGELVVRELDLASLRSVRAFCQEVLQ---------- 131
Query: 508 NAGIFQCPYMKTEDGFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDIN 687
F V K+SAPSRIVVVSSKLYKYGDIN
Sbjct: 132 -------------------FGVNHLGHFLLTNLLLGLLKNSAPSRIVVVSSKLYKYGDIN 172
Query: 688 FEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIP 867
FEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIP
Sbjct: 173 FEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIP 232
Query: 868 LLVKPLFNLVSWAFFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVA 1047
LLV+PLFNLVSWAFFKTP EGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMD+SVA
Sbjct: 233 LLVRPLFNLVSWAFFKTPVEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDESVA 292
Query: 1048 RKLWDISEVMVGILK 1092
RKLWDISEVMVGILK
Sbjct: 293 RKLWDISEVMVGILK 307
>ref|XP_547866.2| PREDICTED: similar to retinol dehydrogenase 12 (all-trans and 9-cis)
[Canis familiaris]
Length = 303
Score = 239 bits (609), Expect = 7e-63
Identities = 129/314 (41%), Positives = 188/314 (59%), Gaps = 3/314 (0%)
Frame = +1
Query: 154 FVGPSVQRLHRGG---DSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARA 324
FV + ++ GG + + GK V+ITGAN+G+G+ TA EL R GARV + CRD +
Sbjct: 4 FVSLAYRKFFAGGVCRSNVQLPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKG 63
Query: 325 EEAAGQLRRELRQTEGPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLI 504
E AA ++R + + ++ ++VR+LDL+ +S+RAF + L EE +L +LI
Sbjct: 64 ESAASEIRADTKNSQ-------------VLVRKLDLSDTKSIRAFAEGFLAEEKQLHILI 110
Query: 505 NNAGIFQCPYMKTEDGFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDI 684
NNAG+ CPY KT DGFE V K S P+R+V +SS + G I
Sbjct: 111 NNAGVMMCPYSKTADGFETHLGVNHLGHFLLTHLLLERLKESTPARVVNLSSVAHHIGKI 170
Query: 685 NFEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHI 864
+F DL E+ Y++ F Y SKLAN+LFTRELA+RL+GT VT +HPG+V + L RH +
Sbjct: 171 HFHDLQGEKRYSRGFAYCHSKLANMLFTRELAKRLQGTGVTTYAVHPGVVSSELVRHSFL 230
Query: 865 PLLVKPLFNLVSWAFFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSV 1044
L+ +F+ F K+ EGAQTS++ A + +E +SGKYF DCK + P+A D+
Sbjct: 231 LCLLWRIFS----PFVKSAREGAQTSLHCALAEGLEPLSGKYFSDCKRAWVSPRARDNKT 286
Query: 1045 ARKLWDISEVMVGI 1086
A +LW++S ++GI
Sbjct: 287 AERLWNVSCELLGI 300
>ref|XP_854127.1| PREDICTED: similar to Retinol dehydrogenase 13 [Canis familiaris]
Length = 334
Score = 237 bits (604), Expect = 3e-62
Identities = 130/295 (44%), Positives = 180/295 (61%), Gaps = 3/295 (1%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
GKTV++TGAN+G+G+ TA EL R G +I+ CRD + E AA ++R E
Sbjct: 38 GKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKEIRGETLNHR------- 90
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
+ LDLASL+S+R F ++++EE ++ +L+NNA + +CP+ T+DGFEMQF
Sbjct: 91 ------VSAWHLDLASLKSIREFAAKIIEEEEQVHILVNNAAVMRCPHWTTKDGFEMQFG 144
Query: 571 VXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLNSE-QSYNKSFCYSRSK 747
V K+SAPSRI+ +SS + G I+F+DLN E + Y+ Y +SK
Sbjct: 145 VNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWEKRKYDTKAAYCQSK 204
Query: 748 LANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNL--VSWAFFKTP 921
LA ILFT+EL+RRL+GT VTVN LHPG+ RT LGRH + F L + W K+P
Sbjct: 205 LAVILFTKELSRRLQGTGVTVNALHPGVARTELGRHTGMHSSAFSSFTLGPIFWLLVKSP 264
Query: 922 AEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGI 1086
AQ S YLA + E+EGVSGKYF KE+ P+A D+ VA++LW S +VG+
Sbjct: 265 QLAAQPSTYLAVAEELEGVSGKYFDGLKEKAPAPEAEDEEVAQRLWAESARLVGL 319
>ref|XP_854354.1| PREDICTED: similar to Retinol dehydrogenase 11 (Retinal reductase 1)
(RalR1) (Prostate short-chain dehydrogenase/reductase 1)
(Androgen-regulated short-chain dehydrogenase/reductase
1) (HCV core-binding protein HCBP12) [Canis familiaris]
Length = 337
Score = 227 bits (578), Expect = 3e-59
Identities = 127/295 (43%), Positives = 174/295 (58%), Gaps = 3/295 (1%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
GK ++TGAN+G+G+ TA EL + GARV + CRD + E A RE++ G ++
Sbjct: 60 GKVAVVTGANTGIGKETAKELAQRGARVYLACRDVLKGELVA----REIQTMTGNKQ--- 112
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
++VR+LDLA +S+RAF + L EE L +LINNAG+ CPY KT DGFEM
Sbjct: 113 ------VLVRKLDLADTKSIRAFAKGFLAEEKHLHILINNAGVMMCPYTKTVDGFEMHMG 166
Query: 571 VXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSRSKL 750
V K SAPSRIV VSS + G I+F DL E+ YN Y SKL
Sbjct: 167 VNHLGHFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHDLQGEKFYNSGLAYCHSKL 226
Query: 751 ANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWA---FFKTP 921
ANILFT+ELARRL+G+ +T +HPG V++ L RH P + W F KTP
Sbjct: 227 ANILFTQELARRLKGSGITAYSVHPGTVKSELVRH-------SPFMKWMWWLFSFFIKTP 279
Query: 922 AEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGI 1086
+GAQTS+Y A + +E +SG +F DC + +A ++++AR+LWD+S ++GI
Sbjct: 280 QQGAQTSLYCAITEGLEVLSGHHFSDCSVAWVSAQARNETIARRLWDVSCDLLGI 334
>ref|XP_548293.2| PREDICTED: similar to retinol dehydrogenase 11 (predicted) [Canis
familiaris]
Length = 377
Score = 207 bits (528), Expect = 2e-53
Identities = 123/301 (40%), Positives = 166/301 (55%), Gaps = 2/301 (0%)
Frame = +1
Query: 190 GDSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTE 369
G + G+T ++TGANSG+G+ TA EL R GARV++ CR R R E AA LR+E
Sbjct: 29 GGIASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQE----- 83
Query: 370 GPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED 549
G E++ LDLASL SVRAF L EPRLD+LI+NAGI C +T
Sbjct: 84 --------SGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCG--RTHK 133
Query: 550 GFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLNSEQS--YNK 723
F + V K+ APSR+VVVSS ++ G ++F L+ +
Sbjct: 134 PFNLLLRVNHIGPFLLTHLLLPRLKTCAPSRVVVVSSAAHRRGRLDFTRLDRPVVGWQQE 193
Query: 724 SFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSW 903
Y+ SKLAN+LF RELA +LEGT VT HPG V + L H+P + PL ++W
Sbjct: 194 LRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLR-HVPGWLCPLLRPLAW 252
Query: 904 AFFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVG 1083
+ P GAQT +Y A +E +SG+YF +C EE+ P A DD A +LW+ S+ + G
Sbjct: 253 LMLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHQLWEASKRLAG 312
Query: 1084 I 1086
+
Sbjct: 313 L 313
>ref|XP_857503.1| PREDICTED: similar to retinol dehydrogenase 14 (all-trans and
9-cis) isoform 3 [Canis familiaris]
Length = 153
Score = 187 bits (475), Expect = 2e-47
Identities = 97/110 (88%), Positives = 100/110 (90%)
Frame = +1
Query: 148 RRFVGPSVQRLHRGGDSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAE 327
RRFVGP VQ+LH GGDSGLMHGKTVLITGANSGLGRATAA LLRLGARVIMGCRDRARAE
Sbjct: 22 RRFVGPGVQQLHGGGDSGLMHGKTVLITGANSGLGRATAAALLRLGARVIMGCRDRARAE 81
Query: 328 EAAGQLRRELRQTEGPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQ 477
EAAGQLRRELRQ G E G + G AGELVVRELDLASLRSVRAFCQE+LQ
Sbjct: 82 EAAGQLRRELRQAGGREPGSDVGAAGELVVRELDLASLRSVRAFCQEVLQ 131
>ref|XP_852222.1| PREDICTED: similar to dehydrogenase/reductase (SDR family) X-linked
[Canis familiaris]
Length = 387
Score = 168 bits (425), Expect = 2e-41
Identities = 109/298 (36%), Positives = 158/298 (53%), Gaps = 7/298 (2%)
Frame = +1
Query: 214 KTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPNS 393
+ ++TG G+G +TA L RLG VI+ + + A + +++ E +
Sbjct: 96 RVAIVTGGTDGIGYSTAKHLARLGMHVILAGNNDSSAPDVVRKIQEETLNDK-------- 147
Query: 394 GGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFAV 573
+ DLASLRS+R F Q+ +++ L VL+NNAG+ P TEDGFE F +
Sbjct: 148 -----VEFLYCDLASLRSIRQFVQKFKKKKIPLHVLVNNAGVMMVPERTTEDGFEEHFGL 202
Query: 574 XXXXXXXXXXXXXXXXKSS-AP---SRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSR 741
K S AP +R+V VSS + G+++ +DL + Y+ Y++
Sbjct: 203 NYLGHFLLTNLLLDTLKESGAPGRCARVVTVSSATHYIGELDMDDLQGSRCYSPHAAYAQ 262
Query: 742 SKLANILFTRELARRL--EGTNVTVNVLHPGIVRTNLGRHIHIPL-LVKPLFNLVSWAFF 912
SKLA +LFT L R L +G+ VT NV+ PG+V TNL RH+ L+K LF W FF
Sbjct: 263 SKLALVLFTYHLQRLLAAQGSPVTANVVDPGVVNTNLYRHVFWGTRLIKKLFG---WWFF 319
Query: 913 KTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGI 1086
KTP EGA TSVY A +P++EG+ G+Y + KE + L D + +LW S M GI
Sbjct: 320 KTPDEGAWTSVYAAVTPDLEGLGGRYLYNEKETKSLAVTYDLDLQTELWARSCQMTGI 377
>ref|XP_533000.2| PREDICTED: similar to Retinol dehydrogenase 12 [Canis familiaris]
Length = 596
Score = 153 bits (387), Expect = 4e-37
Identities = 104/296 (35%), Positives = 160/296 (54%), Gaps = 2/296 (0%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
GKT ++TGANSG+G+A EL R GARVI+ CR+ R ++A +++ + T
Sbjct: 315 GKTAVVTGANSGIGKAVCQELARRGARVILACRNWERGQKALAEIQVASKGT-------- 366
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
L++ ++DL+S+ S+R+F + +LQE P + +L+NNA I P T +G ++ FA
Sbjct: 367 -----CLLLGQVDLSSMASIRSFARWLLQEYPEIHLLVNNAAISGFPKTLTPEGLDLTFA 421
Query: 571 VXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDL-NSEQSYNKSFCYSRSK 747
+ + +R+V VSS + +G ++ + L + + N Y SK
Sbjct: 422 TNYVGPFLLTNLLQGALQRAGSARVVNVSSFRHAHGYVDEKHLTGAGKPLNLIQSYDCSK 481
Query: 748 LANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPAE 927
L FT ELARRL+GT VTVN + PG+V T + + P L + LF L S+ F K +
Sbjct: 482 LLLTSFTGELARRLQGTGVTVNSVDPGVVYTEIMK--PYPWLYRFLFWLFSF-FCKDVKQ 538
Query: 928 GAQTSVYLASSPEVEGVSGKYF-GDCKEEELLPKAMDDSVARKLWDISEVMVGILK 1092
GA +YL+ + E++GVSGKYF C A D VA+ LW+ S + + K
Sbjct: 539 GAIPVLYLSLAKELDGVSGKYFSSSCMITLPTEAAQDPQVAQSLWNASVQLTNLDK 594
>ref|XP_852623.1| PREDICTED: similar to WW domain-containing oxidoreductase isoform 1
[Canis familiaris]
Length = 383
Score = 125 bits (315), Expect = 9e-29
Identities = 83/214 (38%), Positives = 108/214 (50%), Gaps = 8/214 (3%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
GK V++TGANSG+G TA GA VI+ CR+ RA EA Q+ E +
Sbjct: 124 GKVVVVTGANSGIGFETAKSFALHGAHVILACRNMTRANEAVSQILGEWHK--------- 174
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
++ LDLA LRSV+ F Q + L VL+ NA F P+ T+DG E F
Sbjct: 175 ----AKVEAMTLDLALLRSVQHFAQAFKAKNVSLHVLVCNAAAFALPWSLTKDGLETTFQ 230
Query: 571 VXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDIN-------FEDLN-SEQSYNKS 726
V SAP+R+VVVSS+ +++ DIN F L+ S+ Y
Sbjct: 231 VNHLGHFYLVQLLQDVLCRSAPARVVVVSSESHRFTDINDSSGKLDFSRLSPSKSDYWAM 290
Query: 727 FCYSRSKLANILFTRELARRLEGTNVTVNVLHPG 828
Y+RSKL NILF+ EL RRL VT N +HPG
Sbjct: 291 LAYNRSKLCNILFSNELHRRLSPRGVTSNAVHPG 324
Database: RefSeqCP
Posted date: Aug 1, 2006 9:25 PM
Number of letters in database: 19,266,565
Number of sequences in database: 33,732
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,056,216
Number of Sequences: 33732
Number of extensions: 1233805
Number of successful extensions: 4497
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 3812
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4438
length of database: 19,266,565
effective HSP length: 107
effective length of database: 15,657,241
effective search space used: 6372497087
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqHP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= OVRM1_0206_H07
(1544 letters)
Database: RefSeqHP
39,411 sequences; 17,774,539 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_065956.1| retinol dehydrogenase 14 (all-trans and 9-cis) ... 544 e-155
Alignment gi|NP_689656.1| retinol dehydrogenase 12 (all-trans and 9-cis) ... 245 7e-65
Alignment gi|NP_057110.2| androgen-regulated short-chain dehydrogenase/re... 224 2e-58
Alignment gi|NP_612421.1| retinol dehydrogenase 13 (all-trans and 9-cis) ... 202 6e-52
Alignment gi|NP_653284.1| hypothetical protein LOC147015 [Homo sapiens] 181 2e-45
Alignment gi|NP_660160.1| dehydrogenase/reductase (SDR family) X-linked [... 168 1e-41
Alignment gi|NP_057457.1| WW domain-containing oxidoreductase isoform 1 [... 166 7e-41
Alignment gi|XP_371503.3| PREDICTED: similar to short-chain dehydrogenase... 79 1e-14
Alignment gi|XP_947127.1| PREDICTED: similar to short-chain dehydrogenase... 79 1e-14
Alignment gi|NP_001748.1| carbonyl reductase 1 [Homo sapiens] 58 3e-08
>ref|NP_065956.1| retinol dehydrogenase 14 (all-trans and 9-cis) [Homo sapiens]
Length = 336
Score = 544 bits (1402), Expect = e-155
Identities = 280/317 (88%), Positives = 286/317 (90%), Gaps = 2/317 (0%)
Frame = +1
Query: 148 RRFVGPSVQRLHRGGDSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAE 327
RRFVGP VQRL RGGD GLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAE
Sbjct: 22 RRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAE 81
Query: 328 EAAGQLRRELRQTE--GPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVL 501
EAAGQLRRELRQ GPE P G GEL+VRELDLASLRSVRAFCQEMLQEEPRLDVL
Sbjct: 82 EAAGQLRRELRQAAECGPE--PGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVL 139
Query: 502 INNAGIFQCPYMKTEDGFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGD 681
INNAGIFQCPYMKTEDGFEMQF V KSSAPSRIVVVSSKLYKYGD
Sbjct: 140 INNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGD 199
Query: 682 INFEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIH 861
INF+DLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIH
Sbjct: 200 INFDDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIH 259
Query: 862 IPLLVKPLFNLVSWAFFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDS 1041
IPLLVKPLFNLVSWAFFKTP EGAQTS+YLASSPEVEGVSG+YFGDCKEEELLPKAMD+S
Sbjct: 260 IPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSGRYFGDCKEEELLPKAMDES 319
Query: 1042 VARKLWDISEVMVGILK 1092
VARKLWDISEVMVG+LK
Sbjct: 320 VARKLWDISEVMVGLLK 336
>ref|NP_689656.1| retinol dehydrogenase 12 (all-trans and 9-cis) [Homo sapiens]
Length = 316
Score = 245 bits (626), Expect = 7e-65
Identities = 134/313 (42%), Positives = 190/313 (60%), Gaps = 3/313 (0%)
Frame = +1
Query: 157 VGPSVQRLHRGG---DSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAE 327
V PS+++ GG + + GK V+ITGAN+G+G+ TA EL GARV + CRD + E
Sbjct: 18 VAPSIRKFFAGGVCRTNVQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGE 77
Query: 328 EAAGQLRRELRQTEGPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLIN 507
AA ++R + + ++ ++VR+LDL+ +S+RAF + L EE +L +LIN
Sbjct: 78 SAASEIRVDTKNSQ-------------VLVRKLDLSDTKSIRAFAEGFLAEEKQLHILIN 124
Query: 508 NAGIFQCPYMKTEDGFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDIN 687
NAG+ CPY KT DGFE V K SAP+R+V VSS + G I
Sbjct: 125 NAGVMMCPYSKTADGFETHLGVNHLGHFLLTYLLLEQLKVSAPARVVNVSSVAHHIGKIP 184
Query: 688 FEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIP 867
F DL SE+ Y++ F Y SKLAN+LFTRELA+RL+GT VT +HPG+VR+ L RH +
Sbjct: 185 FHDLQSEKRYSRGFAYCHSKLANVLFTRELAKRLQGTGVTTYAVHPGVVRSELVRHSSLL 244
Query: 868 LLVKPLFNLVSWAFFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVA 1047
L+ LF+ F KT EGAQTS++ A + +E +SGKYF DCK + P+A ++ A
Sbjct: 245 CLLWRLFS----PFVKTAREGAQTSLHCALAEGLEPLSGKYFSDCKRTWVSPRARNNKTA 300
Query: 1048 RKLWDISEVMVGI 1086
+LW++S ++GI
Sbjct: 301 ERLWNVSCELLGI 313
>ref|NP_057110.2| androgen-regulated short-chain dehydrogenase/reductase 1 [Homo
sapiens]
Length = 318
Score = 224 bits (570), Expect = 2e-58
Identities = 126/292 (43%), Positives = 177/292 (60%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
GK V++TGAN+G+G+ TA EL + GARV + CRD + E A +E++ T G ++
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVA----KEIQTTTGNQQ--- 93
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
++VR+LDL+ +S+RAF + L EE L VLINNAG+ CPY KT DGFEM
Sbjct: 94 ------VLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIG 147
Query: 571 VXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSRSKL 750
V K SAPSRIV VSS + G I+F +L E+ YN Y SKL
Sbjct: 148 VNHLGHFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKL 207
Query: 751 ANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPAEG 930
ANILFT+ELARRL+G+ VT +HPG V++ L RH + LF+ F KTP +G
Sbjct: 208 ANILFTQELARRLKGSGVTTYSVHPGTVQSELVRHSSFMRWMWWLFSF----FIKTPQQG 263
Query: 931 AQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGI 1086
AQTS++ A + +E +SG +F DC + +A ++++AR+LWD+S ++G+
Sbjct: 264 AQTSLHCALTEGLEILSGNHFSDCHVAWVSVQARNETIARRLWDVSCDLLGL 315
>ref|NP_612421.1| retinol dehydrogenase 13 (all-trans and 9-cis) [Homo sapiens]
Length = 260
Score = 202 bits (514), Expect = 6e-52
Identities = 107/226 (47%), Positives = 143/226 (63%), Gaps = 3/226 (1%)
Frame = +1
Query: 418 RELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFAVXXXXXXXX 597
R LDLASL+S+R F ++++EE R+D+LINNAG+ +CP+ TEDGFEMQF V
Sbjct: 23 RHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLL 82
Query: 598 XXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLN-SEQSYNKSFCYSRSKLANILFTRE 774
K+SAPSRI+ +SS + G I+F+DLN + YN Y +SKLA +LFT+E
Sbjct: 83 TNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKE 142
Query: 775 LARRLEGTNVTVNVLHPGIVRTNLGRH--IHIPLLVKPLFNLVSWAFFKTPAEGAQTSVY 948
L+RRL+G+ VTVN LHPG+ RT LGRH IH + W K+P AQ S Y
Sbjct: 143 LSRRLQGSGVTVNALHPGVARTELGRHTGIHGSTFSSTTLGPIFWLLVKSPELAAQPSTY 202
Query: 949 LASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGI 1086
LA + E+ VSGKYF K++ P+A D+ VAR+LW S +VG+
Sbjct: 203 LAVAEELADVSGKYFDGLKQKAPAPEAEDEEVARRLWAESARLVGL 248
>ref|NP_653284.1| hypothetical protein LOC147015 [Homo sapiens]
Length = 327
Score = 181 bits (458), Expect = 2e-45
Identities = 109/278 (39%), Positives = 151/278 (54%), Gaps = 2/278 (0%)
Frame = +1
Query: 259 TAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPNSGGAGELVVRELDLAS 438
TA EL R GARV++ CR + R E AA LR+E G E++ LDLAS
Sbjct: 2 TALELARRGARVVLACRSQERGEAAAFDLRQE-------------SGNNEVIFMALDLAS 48
Query: 439 LRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFAVXXXXXXXXXXXXXXX 618
L SVRAF L EPRLD+LI+NAGI C +T + F + V
Sbjct: 49 LASVRAFATAFLSSEPRLDILIHNAGISSCG--RTREAFNLLLRVNHIGPFLLTHLLLPC 106
Query: 619 XKSSAPSRIVVVSSKLYKYGDINFEDLNSEQS--YNKSFCYSRSKLANILFTRELARRLE 792
K+ APSR+VVV+S + G ++F+ L+ + Y+ +KLAN+LF RELA +LE
Sbjct: 107 LKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARELANQLE 166
Query: 793 GTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPAEGAQTSVYLASSPEVE 972
T VT HPG V + L H+P ++PL ++W + P GAQT +Y A +E
Sbjct: 167 ATGVTCYAAHPGPVNSELFLR-HVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIE 225
Query: 973 GVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGI 1086
+SG+YF +C EE+ P A DD A +LW+ S+ + G+
Sbjct: 226 PLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGL 263
>ref|NP_660160.1| dehydrogenase/reductase (SDR family) X-linked [Homo sapiens]
Length = 330
Score = 168 bits (425), Expect = 1e-41
Identities = 102/298 (34%), Positives = 155/298 (52%), Gaps = 6/298 (2%)
Frame = +1
Query: 214 KTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPNS 393
+ ++TG G+G +TA L RLG VI+ + ++A++ +++ E +
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDK-------- 95
Query: 394 GGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFAV 573
+ DLAS+ S+R F Q+ ++ L VLINNAG+ P KT DGFE F +
Sbjct: 96 -----VEFLYCDLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGL 150
Query: 574 XXXXXXXXXXXXXXXXKSSAP----SRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSR 741
K S +R+V VSS + ++N +DL S Y+ Y++
Sbjct: 151 NYLGHFLLTNLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQ 210
Query: 742 SKLANILFTRELARRL--EGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFK 915
SKLA +LFT L R L EG++VT NV+ PG+V T+L +H+ + L+ W FK
Sbjct: 211 SKLALVLFTYHLQRLLAAEGSHVTANVVDPGVVNTDLYKHVFWATRLAK--KLLGWLLFK 268
Query: 916 TPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGIL 1089
TP EGA TS+Y A +PE+EGV G+Y + KE + L + + ++LW S M G+L
Sbjct: 269 TPDEGAWTSIYAAVTPELEGVGGRYLYNEKETKSLHVTYNQKLQQQLWSKSCEMTGVL 326
>ref|NP_057457.1| WW domain-containing oxidoreductase isoform 1 [Homo sapiens]
Length = 414
Score = 166 bits (419), Expect = 7e-41
Identities = 108/298 (36%), Positives = 154/298 (51%), Gaps = 8/298 (2%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
GK V++TGANSG+G TA GA VI+ CR+ ARA EA ++ E + +
Sbjct: 124 GKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAK------- 176
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
+ LDLA LRSV+ F + + L VL+ NA F P+ T+DG E F
Sbjct: 177 ------VEAMTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQ 230
Query: 571 VXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDIN-------FEDLN-SEQSYNKS 726
V SAP+R++VVSS+ +++ DIN F L+ ++ Y
Sbjct: 231 VNHLGHFYLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAM 290
Query: 727 FCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWA 906
Y+RSKL NILF+ EL RRL VT N +HPG + + +IH V L ++
Sbjct: 291 LAYNRSKLCNILFSNELHRRLSPRGVTSNAVHPGNMMYS---NIHRSWWVYTLLFTLARP 347
Query: 907 FFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMV 1080
F K+ +GA T+VY A+ PE+EG+ G YF +C P+A + AR LW +SE ++
Sbjct: 348 FTKSMQQGAATTVYCAAVPELEGLGGMYFNNCCRCMPSPEAQSEETARTLWALSERLI 405
>ref|XP_371503.3| PREDICTED: similar to short-chain dehydrogenase/reductase 1 [Homo
sapiens]
Length = 891
Score = 78.6 bits (192), Expect = 1e-14
Identities = 39/120 (32%), Positives = 70/120 (58%), Gaps = 1/120 (0%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
GK ++TGANSG+G+ + +L R GA+VI+ C+ R ++A +++
Sbjct: 602 GKIAIVTGANSGIGKVVSQDLARCGAQVILTCQSRECGQQALAEIQA------------- 648
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIF-QCPYMKTEDGFEMQF 567
+ + L++ E+DL+S+ S+R+F + +LQE P + +L+NNAG+ P T G ++ F
Sbjct: 649 ASNSNRLLLGEVDLSSMTSIRSFARRLLQENPEIHLLVNNAGVSGMIPKTLTPGGLDLTF 708
>ref|XP_947127.1| PREDICTED: similar to short-chain dehydrogenase/reductase 1 [Homo
sapiens]
Length = 916
Score = 78.6 bits (192), Expect = 1e-14
Identities = 39/120 (32%), Positives = 70/120 (58%), Gaps = 1/120 (0%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
GK ++TGANSG+G+ + +L R GA+VI+ C+ R ++A +++
Sbjct: 627 GKIAIVTGANSGIGKVVSQDLARCGAQVILTCQSRECGQQALAEIQA------------- 673
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIF-QCPYMKTEDGFEMQF 567
+ + L++ E+DL+S+ S+R+F + +LQE P + +L+NNAG+ P T G ++ F
Sbjct: 674 ASNSNRLLLGEVDLSSMTSIRSFARRLLQENPEIHLLVNNAGVSGMIPKTLTPGGLDLTF 733
>ref|NP_001748.1| carbonyl reductase 1 [Homo sapiens]
Length = 277
Score = 57.8 bits (138), Expect = 3e-08
Identities = 74/299 (24%), Positives = 119/299 (39%), Gaps = 35/299 (11%)
Frame = +1
Query: 223 LITGANSGLGRATAAELLRL-GARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPNSGG 399
L+TG N G+G A +L RL V++ RD R + A QL Q EG
Sbjct: 9 LVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQL-----QAEGLSPR----- 58
Query: 400 AGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFAVXX 579
+LD+ L+S+RA + +E LDVL+NNAGI T + + +
Sbjct: 59 -----FHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKT 113
Query: 580 XXXXXXXXXXXXXXKSSAPSRIVVVSS---------------KLYKYGDINFEDL----- 699
R+V VSS + ++ I E+L
Sbjct: 114 NFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMN 173
Query: 700 ----NSEQSYNK-----SFCYSRSKLANILFTRELARRL----EGTNVTVNVLHPGIVRT 840
++++ ++ S Y +K+ + +R AR+L +G + +N PG VRT
Sbjct: 174 KFVEDTKKGVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRT 233
Query: 841 NLGRHIHIPLLVKPLFNLVSWAFFKTPAEGAQTSVYLA-SSPEVEGVSGKYFGDCKEEE 1014
++ K+P EGA+T VYLA P+ EG G++ + + E+
Sbjct: 234 ----------------DMAGPKATKSPEEGAETPVYLALLPPDAEGPHGQFVSEKRVEQ 276
Database: RefSeqHP
Posted date: Aug 2, 2006 12:57 AM
Number of letters in database: 17,774,539
Number of sequences in database: 39,411
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,940,738
Number of Sequences: 39411
Number of extensions: 1219058
Number of successful extensions: 4277
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 3592
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4221
length of database: 17,774,539
effective HSP length: 106
effective length of database: 13,596,973
effective search space used: 5547564984
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqSP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= OVRM1_0206_H07
(1544 letters)
Database: RefSeqSP
1040 sequences; 434,620 total letters
Searching...done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_999238.1| 20-beta-hydroxysteroid dehydrogenase [Sus scrofa] 62 3e-11
Alignment gi|NP_999471.1| 17beta-estradiol dehydrogenase [Sus scrofa] 47 9e-07
>ref|NP_999238.1| 20-beta-hydroxysteroid dehydrogenase [Sus scrofa]
Length = 289
Score = 62.4 bits (150), Expect = 3e-11
Identities = 79/303 (26%), Positives = 119/303 (39%), Gaps = 36/303 (11%)
Frame = +1
Query: 214 KTVLITGANSGLGRATAAELLR-LGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
+ L+TGAN G+G A +L R V++ RD AR + A QL Q EG
Sbjct: 6 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQL-----QAEGLSPR-- 58
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
+LD+ L+S+RA C + +E LDVL+NNA I T + +
Sbjct: 59 --------FHQLDIIDLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQAELT 110
Query: 571 VXXXXXXXXXXXXXXXXKSSAPSRIVVVSS---------------KLYKYGDINFEDL-- 699
+ R+V VSS + +K I E+L
Sbjct: 111 MKTNFMGTRNVCTELLPLIKPQGRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVG 170
Query: 700 -------------NSEQSYNKSFCYSRSKLANILFTRELARRLE----GTNVTVNVLHPG 828
+ ++ ++ S Y +K+ + +R AR+L G + +N PG
Sbjct: 171 LMNKFVEDTKNGVHRKEGWSDS-TYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPG 229
Query: 829 IVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPAEGAQTSVYLASSP-EVEGVSGKYFGDCK 1005
VRT++G P K+P GA+T VYLA P + EG G++ D K
Sbjct: 230 WVRTDMGGP-KAP---------------KSPEVGAETPVYLALLPSDAEGPHGQFVTDKK 273
Query: 1006 EEE 1014
E
Sbjct: 274 VVE 276
>ref|NP_999471.1| 17beta-estradiol dehydrogenase [Sus scrofa]
Length = 737
Score = 47.4 bits (111), Expect = 9e-07
Identities = 54/214 (25%), Positives = 85/214 (39%), Gaps = 8/214 (3%)
Frame = +1
Query: 208 HGKTVLITGANSGLGRATAAELLRLGARVIMG-----CRDRARAEEAAGQLRRELRQTEG 372
+G+ VL+TGA GLGR A GA V++ + + AA ++ E+R+ G
Sbjct: 8 YGRVVLVTGAGGGLGRTYALAFAERGASVVVNDLGGDMKGVGKGSLAADKVVEEIRRKGG 67
Query: 373 PE-EGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMK--T 543
+S AGE +V+ L R+DV++NNAGI + +
Sbjct: 68 KAVANYDSVEAGEKIVK---------------AALDAFGRIDVVVNNAGILRDRSFSRIS 112
Query: 544 EDGFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNK 723
++ ++M V K RI++ SS YG NF N
Sbjct: 113 DEDWDMIQRVHLRGSFMVTRAAWDHMKKQNFGRIIMTSSAAGIYG--NFGQAN------- 163
Query: 724 SFCYSRSKLANILFTRELARRLEGTNVTVNVLHP 825
YS +KL + + LA + N+ N + P
Sbjct: 164 ---YSAAKLGLLGLSNSLAVEGKKNNIHCNTVAP 194
Database: RefSeqSP
Posted date: Aug 1, 2006 7:14 PM
Number of letters in database: 434,620
Number of sequences in database: 1040
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,231,276
Number of Sequences: 1040
Number of extensions: 28327
Number of successful extensions: 93
Number of sequences better than 1.0e-05: 2
Number of HSP's better than 0.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 91
length of database: 434,620
effective HSP length: 81
effective length of database: 350,380
effective search space used: 151714540
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Search to RefSeqMP
BLASTX 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= OVRM1_0206_H07
(1544 letters)
Database: RefSeqMP
45,328 sequences; 21,768,885 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_076186.1| alcohol dehydrogenase PAN2 [Mus musculus] 513 e-145
Alignment gi|NP_084293.1| retinol dehydrogenase 12 [Mus musculus] 238 1e-62
Alignment gi|NP_780581.1| retinol dehydrogenase 13 (all-trans and 9-cis) ... 238 1e-62
Alignment gi|NP_067532.2| short-chain dehydrogenase/reductase 1 [Mus musc... 220 4e-57
Alignment gi|NP_001028498.1| dehydrogenase/reductase (SDR family) X chrom... 162 7e-40
Alignment gi|NP_062519.2| WW-domain oxidoreductase [Mus musculus] 161 2e-39
Alignment gi|NP_899109.1| hypothetical protein LOC70451 [Mus musculus] 158 1e-38
Alignment gi|NP_663403.1| hypothetical protein LOC216820 [Mus musculus] 58 3e-08
Alignment gi|NP_598593.1| retinol dehydrogenase 10 [Mus musculus] 53 8e-07
Alignment gi|NP_871789.1| epidermal retinal dehydrogenase 2 [Mus musculus] 50 8e-06
>ref|NP_076186.1| alcohol dehydrogenase PAN2 [Mus musculus]
Length = 334
Score = 513 bits (1321), Expect = e-145
Identities = 265/315 (84%), Positives = 277/315 (87%)
Frame = +1
Query: 148 RRFVGPSVQRLHRGGDSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAE 327
RRF GP QR GGD GLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAE
Sbjct: 23 RRFSGPRNQRQQGGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAE 82
Query: 328 EAAGQLRRELRQTEGPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLIN 507
EAAGQLR+EL Q G GP+ G G+LVV+ELDLASLRSVRAFCQE+LQEEPRLDVLIN
Sbjct: 83 EAAGQLRQELCQAGGA--GPD-GTDGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLIN 139
Query: 508 NAGIFQCPYMKTEDGFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDIN 687
NAG+F CPY KTEDGFEMQF V KSSAPSRIVVVSSKLYKYG+IN
Sbjct: 140 NAGVFHCPYTKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGEIN 199
Query: 688 FEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIP 867
FEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIP
Sbjct: 200 FEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIP 259
Query: 868 LLVKPLFNLVSWAFFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVA 1047
LL +PLFNLVSWAFFKTP EGAQTS+YLA SP+VEGVSG+YFGDCKEEELLPKAMD+SVA
Sbjct: 260 LLARPLFNLVSWAFFKTPLEGAQTSIYLACSPDVEGVSGRYFGDCKEEELLPKAMDESVA 319
Query: 1048 RKLWDISEVMVGILK 1092
RKLWDISEVMVGILK
Sbjct: 320 RKLWDISEVMVGILK 334
>ref|NP_084293.1| retinol dehydrogenase 12 [Mus musculus]
Length = 316
Score = 238 bits (608), Expect = 1e-62
Identities = 127/311 (40%), Positives = 190/311 (61%), Gaps = 3/311 (0%)
Frame = +1
Query: 163 PSVQRLHRGG---DSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEA 333
PS+++ GG + + GK V+ITGAN+G+G+ TA EL R GARV + CRD + E A
Sbjct: 20 PSIRKFFAGGVCTTNVQIPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESA 79
Query: 334 AGQLRRELRQTEGPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNA 513
A ++R + + ++ ++VR+LDL+ +S+RAF + L EE +L +LINNA
Sbjct: 80 ASEIRADTKNSQ-------------VLVRKLDLSDTKSIRAFAERFLAEEKKLHILINNA 126
Query: 514 GIFQCPYMKTEDGFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFE 693
G+ CPY KT DGFE F V K SAP+R+V +SS + G I F
Sbjct: 127 GVMMCPYSKTTDGFETHFGVNHLGHFLLTYLLLERLKESAPARVVNLSSIAHLIGKIRFH 186
Query: 694 DLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLL 873
DL ++ Y +F Y SKLAN+LFTRELA+RL+GT VT +HPG+V + + R+ ++ L
Sbjct: 187 DLQGQKRYCSAFAYGHSKLANLLFTRELAKRLQGTGVTAYAVHPGVVLSEITRNSYLLCL 246
Query: 874 VKPLFNLVSWAFFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARK 1053
+ LF+ FFK+ ++GAQTS++ A + ++E +SGKYF DCK + +A + A +
Sbjct: 247 LWRLFS----PFFKSTSQGAQTSLHCALAEDLEPLSGKYFSDCKRMWVSSRARNKKTAER 302
Query: 1054 LWDISEVMVGI 1086
LW++S ++GI
Sbjct: 303 LWNVSCELLGI 313
>ref|NP_780581.1| retinol dehydrogenase 13 (all-trans and 9-cis) [Mus musculus]
Length = 334
Score = 238 bits (607), Expect = 1e-62
Identities = 131/295 (44%), Positives = 181/295 (61%), Gaps = 3/295 (1%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
GKTV++TGAN+G+G+ TA EL + G VI+ CRD + E AA +R E T P
Sbjct: 38 GKTVIVTGANTGIGKQTALELAKRGGNVILACRDMEKCEVAAKDIRGE---TLNPR---- 90
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
+ LDLASL+S+R F +++++EE R+D+L+NNA + +CP+ TEDGFEMQF
Sbjct: 91 ------VRAERLDLASLKSIREFARKVIKEEERVDILVNNAAVMRCPHWTTEDGFEMQFG 144
Query: 571 VXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLNSE-QSYNKSFCYSRSK 747
V K+SAPSRI+ +SS + G I+FEDLN + + Y+ Y +SK
Sbjct: 145 VNYLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFEDLNWQMKKYDTKAAYCQSK 204
Query: 748 LANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRH--IHIPLLVKPLFNLVSWAFFKTP 921
LA +LFT+EL+ RL+G+ VTVN LHPG+ RT LGRH +H + W FK+P
Sbjct: 205 LAVVLFTKELSHRLQGSGVTVNALHPGVARTELGRHTGMHNSAFSGFMLGPFFWLLFKSP 264
Query: 922 AEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGI 1086
AQ S YLA + E+E VSGKYF +E+ P+A D+ VAR+LW S +VG+
Sbjct: 265 QLAAQPSTYLAVAEELENVSGKYFDGLREKAPSPEAEDEEVARRLWTESARLVGL 319
>ref|NP_067532.2| short-chain dehydrogenase/reductase 1 [Mus musculus]
Length = 316
Score = 220 bits (560), Expect = 4e-57
Identities = 128/313 (40%), Positives = 185/313 (59%), Gaps = 3/313 (0%)
Frame = +1
Query: 157 VGPSVQRLHRGG---DSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAE 327
V P ++++ G + + GK ++TGAN+G+G+ TA +L + GARV + CRD + E
Sbjct: 17 VTPKIRKMLSSGVCTSNVQLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGE 76
Query: 328 EAAGQLRRELRQTEGPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLIN 507
AA RE++ G NS ++ VR+LDLA +S+RAF ++ L EE L +LIN
Sbjct: 77 LAA----REIQAVTG-----NS----QVFVRKLDLADTKSIRAFAKDFLAEEKHLHLLIN 123
Query: 508 NAGIFQCPYMKTEDGFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDIN 687
NAG+ CPY KT DGFEM V K SAPSRIV +SS + G I+
Sbjct: 124 NAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIVNLSSLGHHLGRIH 183
Query: 688 FEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIP 867
F +L E+ Y+ Y SKLANILFT+ELA+RL+G+ VT +HPG V + L R+ I
Sbjct: 184 FHNLQGEKFYSAGLAYCHSKLANILFTKELAKRLKGSGVTTYSVHPGTVHSELTRYSSIM 243
Query: 868 LLVKPLFNLVSWAFFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVA 1047
+ LF + F KTP EGAQTS+Y A + +E +SG +F DC+ + + ++ +A
Sbjct: 244 RWLWQLF----FVFIKTPQEGAQTSLYCALTEGLESLSGSHFSDCQLAWVSYQGRNEIIA 299
Query: 1048 RKLWDISEVMVGI 1086
R+LWD+S ++G+
Sbjct: 300 RRLWDVSCDLLGL 312
>ref|NP_001028498.1| dehydrogenase/reductase (SDR family) X chromosome [Mus musculus]
Length = 335
Score = 162 bits (411), Expect = 7e-40
Identities = 104/289 (35%), Positives = 146/289 (50%), Gaps = 6/289 (2%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
G+ ++TGA +G+GR+TA +L RLG V++ D R +E +R E+
Sbjct: 43 GRVAIVTGATAGIGRSTARQLARLGMCVVVAGNDEHRGQEVVSSIRAEM----------- 91
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
G+ LDLASL SVR F ++ L +L+NNAG+ P +TEDGFE
Sbjct: 92 --GSDRAHFLPLDLASLASVRGFARDFQALGLPLHLLVNNAGVMLEPRAETEDGFERHLG 149
Query: 571 VXXXXXXXXXXXXXXXXKSSAP----SRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYS 738
V ++S SR+V V S + G ++ DL+ +Y+ Y+
Sbjct: 150 VNFLGHFLLTLLLLPALRASGAEGRGSRVVTVGSATHYVGTVDMADLHGRHAYSPYAAYA 209
Query: 739 RSKLANILFTRELARRLE--GTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFF 912
+SKLA LF +L R L+ G VT N+ PG+V T L RH L F + W F
Sbjct: 210 QSKLALALFALQLQRILDARGDPVTSNMADPGVVDTELYRHAGWVLRTAKRF--LGWLVF 267
Query: 913 KTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLW 1059
K+P EGA T VY A++PE+EGV G+Y D E E L A D + R+LW
Sbjct: 268 KSPEEGAWTLVYAAAAPELEGVGGRYLRDEAEAEPLGTARDQELQRRLW 316
>ref|NP_062519.2| WW-domain oxidoreductase [Mus musculus]
Length = 414
Score = 161 bits (408), Expect = 2e-39
Identities = 107/298 (35%), Positives = 152/298 (51%), Gaps = 8/298 (2%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
GK VL+TGANSG+G TA GA VI+ CR+ +RA EA ++ E +
Sbjct: 124 GKVVLVTGANSGIGFETAKSFALHGAHVILACRNLSRASEAVSRILEEWHK--------- 174
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFA 570
++ LDLA LRSV+ F + + L VL+ NAG F P+ T+DG E F
Sbjct: 175 ----AKVEAMTLDLAVLRSVQHFAEAFKAKNVSLHVLVCNAGTFALPWGLTKDGLETTFQ 230
Query: 571 VXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFE----DLN----SEQSYNKS 726
V S+P+R++VVSS+ +++ DIN DL+ Y
Sbjct: 231 VNHLGHFYLVQLLQDVLCRSSPARVIVVSSESHRFTDINDSSGKLDLSRLSPPRSDYWAM 290
Query: 727 FCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWA 906
Y+RSKL NILF+ EL RRL VT N +HPG + + IH V L ++
Sbjct: 291 LAYNRSKLCNILFSNELHRRLSPRGVTSNAVHPGNMMYSA---IHRNSWVYKLLFTLARP 347
Query: 907 FFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMV 1080
F K+ +GA T+VY A +PE+EG+ G YF +C +A + AR LW++SE ++
Sbjct: 348 FTKSMQQGAATTVYCAVAPELEGLGGMYFNNCCRCLPSEEAQSEETARALWELSERLI 405
>ref|NP_899109.1| hypothetical protein LOC70451 [Mus musculus]
Length = 260
Score = 158 bits (400), Expect = 1e-38
Identities = 98/240 (40%), Positives = 133/240 (55%), Gaps = 2/240 (0%)
Frame = +1
Query: 190 GDSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTE 369
G G + G+TV++TGANSG+G+ TA EL R GARV++ CR R R E AA LR+E
Sbjct: 29 GGIGSLRGRTVVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQE----- 83
Query: 370 GPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED 549
G E++ LDLASL SV+AF L EPRLDVLI+NAGI C +T +
Sbjct: 84 --------SGNNEVIFMALDLASLASVQAFATAFLSSEPRLDVLIHNAGISSCG--RTRE 133
Query: 550 GFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLNSEQS--YNK 723
F + V +S APSR+V+VSS ++ G ++F L+ +
Sbjct: 134 TFNLLLRVNHVGPFLLTHLLLPRLRSCAPSRVVIVSSAAHRRGRLDFTRLDCPVVGWQQE 193
Query: 724 SFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSW 903
Y+ SKLAN+LF RELA +LEGT VT HPG V + L H+ ++P+ ++W
Sbjct: 194 LRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLR-HLRGWLRPILRPLAW 252
>ref|NP_663403.1| hypothetical protein LOC216820 [Mus musculus]
Length = 323
Score = 57.8 bits (138), Expect = 3e-08
Identities = 63/223 (28%), Positives = 89/223 (39%)
Frame = +1
Query: 178 LHRGGDSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRREL 357
L R + V++TGA SGLGR A GA++++ C +A E +L REL
Sbjct: 41 LQRIRSKAYLRNAVVVVTGATSGLGRECAKVFHAAGAKLVL-CGRNVKALE---ELSREL 96
Query: 358 RQTEGPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYM 537
G + G + V DLA ++ A E+LQ +DVLINNAGI Y
Sbjct: 97 -------AGSSQGQTHQPFVVTFDLADPGTIAAAAAEILQCFGYVDVLINNAGI---SYR 146
Query: 538 KTEDGFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSY 717
T + V K+ PS + + + + + S
Sbjct: 147 GTIS--DTIVDVDRKVMEINYFGPVALTKALLPSMVERKQGHI-----VAISSIQGKISI 199
Query: 718 NKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNL 846
YS SK A F L +E N+ V V+ PG + TNL
Sbjct: 200 PFRSAYSASKHATQAFFDCLRAEMEEANIKVTVISPGYIHTNL 242
>ref|NP_598593.1| retinol dehydrogenase 10 [Mus musculus]
Length = 341
Score = 53.1 bits (126), Expect = 8e-07
Identities = 58/243 (23%), Positives = 88/243 (36%), Gaps = 19/243 (7%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
G+ LITGA SGLGR A E R A +++ + EE AG +R R E +
Sbjct: 36 GQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAAL 95
Query: 391 SGGAGE----------LVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGI------F 522
G GE + D+ +V + + +E + VL+NNAG+
Sbjct: 96 QAGKGEEEILPPCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLL 155
Query: 523 QCPYMKTEDGFEMQFAVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGDINFEDLN 702
+CP ++ E V IV V+S L + ED
Sbjct: 156 ECP----DELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVED-- 209
Query: 703 SEQSYNKSFCYSRSKLANILFTRELARRL---EGTNVTVNVLHPGIVRTNLGRHIHIPLL 873
Y SK + F L+ L E + ++ P +V T + R I
Sbjct: 210 ----------YCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKE 259
Query: 874 VKP 882
++P
Sbjct: 260 IEP 262
>ref|NP_871789.1| epidermal retinal dehydrogenase 2 [Mus musculus]
Length = 309
Score = 49.7 bits (117), Expect = 8e-06
Identities = 39/125 (31%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Frame = +1
Query: 211 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPN 390
G+ VLITGA SGLGR A + RLGA +++ ++ A + QL RE
Sbjct: 40 GEIVLITGAGSGLGRLLALQFARLGAVLVLWDVNK-EANDETHQLARE------------ 86
Query: 391 SGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGI------FQCPYMKTEDG 552
GA + D + V ++ +E + +LINNAGI CP E
Sbjct: 87 -AGAARVHAYTCDCSRREEVYRVADQVKKEVGDVSILINNAGIVTGRNFLDCPDDLMEKS 145
Query: 553 FEMQF 567
F++ F
Sbjct: 146 FDVNF 150
Database: RefSeqMP
Posted date: Aug 2, 2006 12:58 AM
Number of letters in database: 21,768,885
Number of sequences in database: 45,328
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,972,055
Number of Sequences: 45328
Number of extensions: 1424821
Number of successful extensions: 4842
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 4173
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4784
length of database: 21,768,885
effective HSP length: 108
effective length of database: 16,873,461
effective search space used: 6850625166
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)