Animal-Genome cDNA BFLT1_0085_G08

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BFLT1_0085_G08
         (3148 letters)

Database: RefSeq49_BP.fasta 
           33,088 sequences; 17,681,374 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_001070264.1| amyloid beta A4 protein [Bos taurus].             769   0.0  
Alignment   gi|XP_002699281.1| PREDICTED: amyloid beta (A4) precursor-like ...   445   e-124
Alignment   gi|XP_001251235.1| PREDICTED: amyloid beta (A4) precursor-like ...   445   e-124
Alignment   gi|NP_001033184.1| amyloid-like protein 1 [Bos taurus].              243   8e-64
Alignment   gi|NP_001039436.1| kunitz-type protease inhibitor 2 [Bos taurus].     69   3e-11
Alignment   gi|NP_001070530.1| eppin [Bos taurus].                                67   1e-10
Alignment   gi|NP_001001554.2| pancreatic trypsin inhibitor precursor [Bos ...    65   3e-10
Alignment   gi|XP_002692379.1| PREDICTED: tissue factor pathway inhibitor-l...    62   2e-09
Alignment   gi|XP_002701177.1| PREDICTED: tissue factor pathway inhibitor-l...    62   2e-09
Alignment   gi|XP_002685288.1| PREDICTED: tissue factor pathway inhibitor (...    62   4e-09

>ref|NP_001070264.1| amyloid beta A4 protein [Bos taurus].
          Length = 695

 Score =  770 bits (1987), Expect = 0.0
 Identities = 387/407 (95%), Positives = 389/407 (95%)
 Frame = +2

Query: 1229 IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 1408
            +PTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL
Sbjct: 289  VPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 348

Query: 1409 PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 1588
            PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
Sbjct: 349  PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 408

Query: 1589 PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 1768
            PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ
Sbjct: 409  PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 468

Query: 1769 SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 1948
            SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLAN+ISEPRISYGNDALMPSLTETKTT
Sbjct: 469  SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANIISEPRISYGNDALMPSLTETKTT 528

Query: 1949 VELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT 2128
            VELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
Sbjct: 529  VELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT 588

Query: 2129 EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXX 2308
            EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGL                  
Sbjct: 589  EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVML 648

Query: 2309 KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
            KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 649  KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 695



 Score =  437 bits (1123), Expect = e-122
 Identities = 211/268 (78%), Positives = 213/268 (79%)
 Frame = +2

Query: 197  MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 376
            MLP LALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK
Sbjct: 1    MLPALALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 60

Query: 377  TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 556
            TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR RKQCKTH H+VIPYRCLVG
Sbjct: 61   TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHAHMVIPYRCLVG 120

Query: 557  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 736
            EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
Sbjct: 121  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 180

Query: 737  GVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXX 916
            GVEFVCCPL                  VWWGGADTDYADGSEDKV+              
Sbjct: 181  GVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVIEVAEEEEVADVEEE 240

Query: 917  XXXXXXXXXXXXXXXXXXXXPYEEATER 1000
                                PYEEATER
Sbjct: 241  EADDEEDDEDGEELEEEAEEPYEEATER 268


>ref|XP_002699281.1| PREDICTED: amyloid beta (A4) precursor-like protein 2 [Bos taurus].
          Length = 767

 Score =  445 bits (1145), Expect = e-124
 Identities = 245/479 (51%), Positives = 316/479 (65%), Gaps = 19/479 (3%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAA 1246
            CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC ++IP T  
Sbjct: 314  CSQEALTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPTPL 373

Query: 1247 STPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKK 1426
             T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNLPKA+++
Sbjct: 374  PTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQ 432

Query: 1427 AVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRH 1606
             +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ PPRP  
Sbjct: 433  TLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRVALENYLAALQSDPPRPHR 492

Query: 1607 VFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLY 1786
            +   L++YVRAE KDR HTL+H++HV  VDP+KAAQ+RSQVMTHL VI ER NQSLSLLY
Sbjct: 493  ILQALRRYVRAENKDRLHTLRHYQHVLAVDPEKAAQMRSQVMTHLHVIEERRNQSLSLLY 552

Query: 1787 NVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPV 1966
             VP VA+EIQ+E+DELLQ+++       A+M          D    S +ET   V    V
Sbjct: 553  KVPYVAQEIQEEIDELLQEQR-------ADM----------DQFSSSFSETPVDVR---V 592

Query: 1967 NGEFSLDDLQPWHPFGVDSVPANTENE-VEPVDARPAADRGLTTRPGSGLTNIKTEEI-S 2140
            + E S D++ P+H   +   P+  ENE  +P    P            GL   + + I S
Sbjct: 593  SSEES-DEIPPFH--SLHPFPSLPENEDSQPELFHPMKKGSALGEQDGGLIGAEEKVINS 649

Query: 2141 EVKMDAEFRHDSGYEVHHQKLVFFAEDVGS-----------------NKGAIIGLXXXXX 2269
            + K+D     D   +V  ++++F AE VG                  +  A+IGL     
Sbjct: 650  KKKVDENMVIDETLDV--KEMIFNAERVGGLEEEPESVGPLREDFSLSSSALIGLLVVAV 707

Query: 2270 XXXXXXXXXXXXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 2446
                         +++QY SI HG+VEVD  +TPEERHLSKMQ +GYENPTYK+ EQMQ
Sbjct: 708  AIATIIVISLVMLRRRQYGSISHGIVEVDPMLTPEERHLSKMQNHGYENPTYKYLEQMQ 766



 Score =  265 bits (676), Expect = 2e-70
 Identities = 120/201 (59%), Positives = 152/201 (75%), Gaps = 2/201 (0%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEV--PTDGNAGLLAEPQVAMFCGKLNMHMNV 337
           ++A  A  ++ +L  L L   AA  A  +E    + G    +AEPQ+AMFCGKLNMH+N+
Sbjct: 6   TAATAATGKLLVLLLLGLTAPAAALAGYIEALAASAGTGFAVAEPQIAMFCGKLNMHVNI 65

Query: 338 QNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKT 517
           Q G+WE DPSGT++C GTKE +LQYCQE+YPELQITNV+EANQPV++ NWC+R +KQCK 
Sbjct: 66  QTGRWEPDPSGTQSCFGTKEEVLQYCQEMYPELQITNVMEANQPVSVDNWCRRDKKQCK- 124

Query: 518 HTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHD 697
            +HIVIP++CLVGEFVSD LLVP+KC F H+ERM+VCE H  WHTV KE C  +   L+ 
Sbjct: 125 -SHIVIPFKCLVGEFVSDVLLVPEKCLFFHKERMEVCENHQRWHTVVKEACLTQEMTLYS 183

Query: 698 YGMLLPCGIDKFRGVEFVCCP 760
           Y MLLPCG+D+F G E+VCCP
Sbjct: 184 YSMLLPCGVDQFHGTEYVCCP 204


>ref|XP_001251235.1| PREDICTED: amyloid beta (A4) precursor-like protein 2 [Bos taurus].
          Length = 767

 Score =  445 bits (1145), Expect = e-124
 Identities = 245/479 (51%), Positives = 316/479 (65%), Gaps = 19/479 (3%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAA 1246
            CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC ++IP T  
Sbjct: 314  CSQEALTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPTPL 373

Query: 1247 STPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKK 1426
             T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNLPKA+++
Sbjct: 374  PTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQ 432

Query: 1427 AVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRH 1606
             +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ PPRP  
Sbjct: 433  TLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRVALENYLAALQSDPPRPHR 492

Query: 1607 VFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLY 1786
            +   L++YVRAE KDR HTL+H++HV  VDP+KAAQ+RSQVMTHL VI ER NQSLSLLY
Sbjct: 493  ILQALRRYVRAENKDRLHTLRHYQHVLAVDPEKAAQMRSQVMTHLHVIEERRNQSLSLLY 552

Query: 1787 NVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPV 1966
             VP VA+EIQ+E+DELLQ+++       A+M          D    S +ET   V    V
Sbjct: 553  KVPYVAQEIQEEIDELLQEQR-------ADM----------DQFSSSFSETPVDVR---V 592

Query: 1967 NGEFSLDDLQPWHPFGVDSVPANTENE-VEPVDARPAADRGLTTRPGSGLTNIKTEEI-S 2140
            + E S D++ P+H   +   P+  ENE  +P    P            GL   + + I S
Sbjct: 593  SSEES-DEIPPFH--SLHPFPSLPENEDSQPELFHPMKKGSALGEQDGGLIGAEEKVINS 649

Query: 2141 EVKMDAEFRHDSGYEVHHQKLVFFAEDVGS-----------------NKGAIIGLXXXXX 2269
            + K+D     D   +V  ++++F AE VG                  +  A+IGL     
Sbjct: 650  KKKVDENMVIDETLDV--KEMIFNAERVGGLEEEPESVGPLREDFSLSSSALIGLLVVAV 707

Query: 2270 XXXXXXXXXXXXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 2446
                         +++QY SI HG+VEVD  +TPEERHLSKMQ +GYENPTYK+ EQMQ
Sbjct: 708  AIATIIVISLVMLRRRQYGSISHGIVEVDPMLTPEERHLSKMQNHGYENPTYKYLEQMQ 766



 Score =  265 bits (676), Expect = 2e-70
 Identities = 120/201 (59%), Positives = 152/201 (75%), Gaps = 2/201 (0%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEV--PTDGNAGLLAEPQVAMFCGKLNMHMNV 337
           ++A  A  ++ +L  L L   AA  A  +E    + G    +AEPQ+AMFCGKLNMH+N+
Sbjct: 6   TAATAATGKLLVLLLLGLTAPAAALAGYIEALAASAGTGFAVAEPQIAMFCGKLNMHVNI 65

Query: 338 QNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKT 517
           Q G+WE DPSGT++C GTKE +LQYCQE+YPELQITNV+EANQPV++ NWC+R +KQCK 
Sbjct: 66  QTGRWEPDPSGTQSCFGTKEEVLQYCQEMYPELQITNVMEANQPVSVDNWCRRDKKQCK- 124

Query: 518 HTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHD 697
            +HIVIP++CLVGEFVSD LLVP+KC F H+ERM+VCE H  WHTV KE C  +   L+ 
Sbjct: 125 -SHIVIPFKCLVGEFVSDVLLVPEKCLFFHKERMEVCENHQRWHTVVKEACLTQEMTLYS 183

Query: 698 YGMLLPCGIDKFRGVEFVCCP 760
           Y MLLPCG+D+F G E+VCCP
Sbjct: 184 YSMLLPCGVDQFHGTEYVCCP 204


>ref|NP_001033184.1| amyloid-like protein 1 [Bos taurus].
          Length = 642

 Score =  243 bits (620), Expect = 8e-64
 Identities = 151/401 (37%), Positives = 218/401 (54%), Gaps = 6/401 (1%)
 Frame = +2

Query: 1256 DAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVI 1435
            D VD Y   PG+ +EH  F +AK  LE +   ++++VMREW  A+ Q+KNLPKAD++A+ 
Sbjct: 287  DGVDVYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALN 346

Query: 1436 QHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN 1615
            +HFQ  +++LE++ + ERQ+LVETH  RV A++ND+RR ALE ++ ALQ  PP+P  V  
Sbjct: 347  EHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQGDPPQPERVLL 406

Query: 1616 MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVP 1795
             L++Y+RAEQK+++HTL+H++HV  VDP+KA Q+R QV THL+VI ERMNQSL LL   P
Sbjct: 407  ALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVQTHLQVIEERMNQSLGLLDQNP 466

Query: 1796 AVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGE 1975
             +A+E++ ++ ELL  E                       L P+  E        P +G 
Sbjct: 467  RLAQELRPQIQELLHSEH----------------------LGPNELEA-------PASGG 497

Query: 1976 FSLD--DLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVK 2149
             S D   LQP  P G   +    E +                   SG   +   E  E K
Sbjct: 498  SSEDKSGLQPLDPKGDTPMALPKEQDA----------------TSSGKDKMTPLEQYERK 541

Query: 2150 MDAEFRHDSGYEVHH---QKLVFFAEDVGSNKGAIIG-LXXXXXXXXXXXXXXXXXXKKK 2317
            ++       G+  H    Q+        G ++ A+ G L                  +KK
Sbjct: 542  VNMSI--PRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSLLLLRRKK 599

Query: 2318 QYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQ 2440
             Y +I HGVVEVD  +T EE+ L ++Q++GYENPTY+F E+
Sbjct: 600  PYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEE 640



 Score =  177 bits (448), Expect = 7e-44
 Identities = 86/202 (42%), Positives = 122/202 (60%), Gaps = 1/202 (0%)
 Frame = +2

Query: 158 ANSSALGAPRRVAMLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNV 337
           A+ +  G    + +LP L L+L        L   +   A      QVA  CG+  +H ++
Sbjct: 4   ASPATRGLGPLLRLLPLLMLLLRMQLAEGNLAGGSPSAAEAPGSAQVAGLCGRPTLHRDL 63

Query: 338 QNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRK-QCK 514
           + G+WE DP  ++ C+   + +L+YC+++YPELQI  V +A Q + ++ WC  +R   C 
Sbjct: 64  RTGRWEPDPQLSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMEQWCGGTRGGHCA 123

Query: 515 THTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLH 694
              H V+P+ CL GEFVS+ALLVP+ C+FLHQERMD CE+       A+E CS +   LH
Sbjct: 124 HPHHQVVPFHCLPGEFVSEALLVPEGCRFLHQERMDQCESSARRQQEAQEACSSQGLILH 183

Query: 695 DYGMLLPCGIDKFRGVEFVCCP 760
             GMLLPCG D+FRGVE+VCCP
Sbjct: 184 GSGMLLPCGADRFRGVEYVCCP 205


>ref|NP_001039436.1| kunitz-type protease inhibitor 2 [Bos taurus].
          Length = 250

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 27/51 (52%), Positives = 33/51 (64%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 1219
            C  +A TGPCRA   RWYF+  E  C  F YGGC GN+NN+ ++E CM  C
Sbjct: 131  CIAKAVTGPCRAAFPRWYFNAEENSCDNFIYGGCRGNKNNYRSKEECMQQC 181



 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 26/58 (44%), Positives = 34/58 (58%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTT 1240
            C    + G CRA   RW+++VT+G C  F YGGC  N NN+ T+E C+A C  V   T
Sbjct: 38   CHLPKKVGRCRASFPRWWYNVTDGSCQQFVYGGCDRNDNNYMTKEECLAKCAGVTENT 95


>ref|NP_001070530.1| eppin [Bos taurus].
          Length = 134

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 24/53 (45%), Positives = 32/53 (60%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 1225
            CS   E GPC A+  RW++D T   C+ F YGGC GN NNF ++  C + C +
Sbjct: 77   CSMPKEAGPCMALFHRWWYDKTNNSCSSFIYGGCRGNNNNFQSQAVCQSACSA 129


>ref|NP_001001554.2| pancreatic trypsin inhibitor precursor [Bos taurus].
          Length = 100

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 26/55 (47%), Positives = 33/55 (60%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVI 1231
            C E   TGPC+A + R++++   G C PF YGGC   RNNF + E CM  CG  I
Sbjct: 40   CLEPPYTGPCKARMIRYFYNAKAGLCQPFVYGGCRAKRNNFKSSEDCMRTCGGAI 94


>ref|XP_002692379.1| PREDICTED: tissue factor pathway inhibitor-like [Bos taurus].
          Length = 158

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 23/51 (45%), Positives = 32/51 (62%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 1219
            C      GPC+A + R++++ T   C PF YGGC GN NNF+T E C+ +C
Sbjct: 44   CQLPQARGPCKAALLRYFYNSTSNACEPFTYGGCQGNDNNFETTEMCLRIC 94


>ref|XP_002701177.1| PREDICTED: tissue factor pathway inhibitor-like [Bos taurus].
          Length = 158

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 23/51 (45%), Positives = 32/51 (62%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 1219
            C      GPC+A + R++++ T   C PF YGGC GN NNF+T E C+ +C
Sbjct: 44   CQLPQARGPCKAALLRYFYNSTSNACEPFTYGGCQGNDNNFETTEMCLRIC 94


>ref|XP_002685288.1| PREDICTED: tissue factor pathway inhibitor (lipoprotein-associated
            coagulation inhibitor) isoform 2 [Bos taurus].
          Length = 304

 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 25/68 (36%), Positives = 37/68 (54%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAA 1246
            C+ + + GPC+AMI R++F++   +C  F YGGC GN+N F+T E C   C    P    
Sbjct: 50   CAMRVDDGPCKAMIKRFFFNIHTQQCEEFIYGGCKGNQNRFETLEECKQKCTRDYPKNTR 109

Query: 1247 STPDAVDK 1270
                 + K
Sbjct: 110  KMKTTLQK 117



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 22/51 (43%), Positives = 32/51 (62%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 1219
            C   A+ G C+A ++R+Y++   G C PF Y GCGGN NNF + + C+  C
Sbjct: 216  CLTPADRGLCQANVTRFYYNSVIGNCLPFKYSGCGGNENNFTSRKACVRAC 266



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 21/51 (41%), Positives = 30/51 (58%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 1219
            C  + +TG CR  I R++++    +C  F YGGC GN NNF++ E C   C
Sbjct: 123  CFLEEDTGICRGYIIRYFYNNQSKQCERFTYGGCLGNLNNFESLEECKNTC 173


  Database: RefSeq49_BP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 17,681,374
  Number of sequences in database:  33,088
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33088
Number of Hits to DB: 115,068,660
Number of extensions: 3157665
Number of successful extensions: 11846
Number of sequences better than 1.0e-05: 43
Number of HSP's gapped: 11726
Number of HSP's successfully gapped: 61
Length of query: 1049
Length of database: 17,681,374
Length adjustment: 113
Effective length of query: 936
Effective length of database: 13,942,430
Effective search space: 13050114480
Effective search space used: 13050114480
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BFLT1_0085_G08
         (3148 letters)

Database: RefSeq49_CP.fasta 
           33,336 sequences; 18,874,504 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_001006601.1| amyloid beta A4 protein [Canis lupus familia...  1292   0.0  
Alignment   gi|XP_856859.1| PREDICTED: similar to Amyloid-like protein 2 pr...   448   e-125
Alignment   gi|XP_856781.1| PREDICTED: similar to Amyloid-like protein 2 pr...   448   e-125
Alignment   gi|XP_855958.1| PREDICTED: similar to Amyloid-like protein 2 pr...   448   e-125
Alignment   gi|XP_536530.2| PREDICTED: similar to Amyloid-like protein 2 pr...   448   e-125
Alignment   gi|XP_856696.1| PREDICTED: similar to Amyloid-like protein 2 pr...   448   e-125
Alignment   gi|XP_856617.1| PREDICTED: similar to Amyloid-like protein 2 pr...   448   e-125
Alignment   gi|XP_856451.1| PREDICTED: similar to Amyloid-like protein 2 pr...   443   e-124
Alignment   gi|XP_856494.1| PREDICTED: similar to Amyloid-like protein 2 pr...   439   e-123
Alignment   gi|XP_856283.1| PREDICTED: similar to Amyloid-like protein 2 pr...   439   e-123

>ref|NP_001006601.1| amyloid beta A4 protein [Canis lupus familiaris].
          Length = 770

 Score = 1292 bits (3344), Expect = 0.0
 Identities = 647/770 (84%), Positives = 652/770 (84%), Gaps = 19/770 (2%)
 Frame = +2

Query: 197  MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 376
            MLP LALVLLA+WTARALEVPTDGNAGLLAEPQVAM CGKL MHMNVQNGKWESDP GTK
Sbjct: 1    MLPALALVLLASWTARALEVPTDGNAGLLAEPQVAMLCGKLRMHMNVQNGKWESDPLGTK 60

Query: 377  TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 556
            TCIG+KE ILQYCQEVYPELQITNVVEANQPVTIQNWCK+ RKQCKTH HIVIPYRCLVG
Sbjct: 61   TCIGSKEDILQYCQEVYPELQITNVVEANQPVTIQNWCKKGRKQCKTHAHIVIPYRCLVG 120

Query: 557  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 736
            EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
Sbjct: 121  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 180

Query: 737  GVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXX 916
            GVEFVCCPL                  VWWGGADTDYADGSEDKVV              
Sbjct: 181  GVEFVCCPLAEESDNIDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVADVEEE 240

Query: 917  XXXXXXXXXXXXXXXXXXXXPYEEATERXXXXXXXXXXXXXXXXXXXXXXCSEQAETGPC 1096
                                PYEEATER                      CSEQAETGPC
Sbjct: 241  EAEDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPC 300

Query: 1097 RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSV---------------- 1228
            RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSV                
Sbjct: 301  RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVMSQSLLKTTQEPLPQD 360

Query: 1229 ---IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA 1399
               +PTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA
Sbjct: 361  AVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA 420

Query: 1400 KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL 1579
            KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL
Sbjct: 421  KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL 480

Query: 1580 QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER 1759
            QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER
Sbjct: 481  QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER 540

Query: 1760 MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET 1939
            MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDD+LANMISEPRISYGNDALMPSLTET
Sbjct: 541  MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDILANMISEPRISYGNDALMPSLTET 600

Query: 1940 KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTN 2119
            KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTN
Sbjct: 601  KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTN 660

Query: 2120 IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXX 2299
            IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGL               
Sbjct: 661  IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITL 720

Query: 2300 XXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
               KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 721  VMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 770


>ref|XP_856859.1| PREDICTED: similar to Amyloid-like protein 2 precursor (Amyloid
            protein homolog) (APPH) (CDEI-box binding protein)
            (CDEBP) isoform 26 [Canis familiaris].
          Length = 755

 Score =  448 bits (1153), Expect = e-125
 Identities = 239/465 (51%), Positives = 311/465 (66%), Gaps = 5/465 (1%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAA 1246
            CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC ++IP T  
Sbjct: 314  CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTMIPPTPL 373

Query: 1247 STPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKK 1426
             T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNLPKA+++
Sbjct: 374  PTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQ 432

Query: 1427 AVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRH 1606
             +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ PPRP  
Sbjct: 433  TLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHR 492

Query: 1607 VFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLY 1786
            +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI ER NQSLSLLY
Sbjct: 493  ILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLY 552

Query: 1787 NVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPV 1966
             VP VA+EIQ+E+DELLQ+++       A+M          D    S++ET   V    V
Sbjct: 553  KVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVDVR---V 592

Query: 1967 NGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARP----AADRGLTTRPGSGLTNIKTEE 2134
            + E S D++ P+HPF     P+  ENE      +      A+  +         N+  +E
Sbjct: 593  SSEES-DEIPPFHPF--HPFPSLPENEGSGAGEQDGGLIGAEEKVINSKNKVDENMVIDE 649

Query: 2135 ISEVK-MDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXXK 2311
              +VK M        G E   + +    ED   +  A+IGL                  +
Sbjct: 650  TLDVKEMIFNAERVGGLEAEPESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLR 709

Query: 2312 KKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 2446
            K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 710  KRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 754



 Score =  267 bits (682), Expect = 5e-71
 Identities = 121/202 (59%), Positives = 155/202 (76%), Gaps = 3/202 (1%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEVPTDGNAGL---LAEPQVAMFCGKLNMHMN 334
           ++A  A  ++ +L  L L   AA  A  +E     NAG    +AEPQ+A+FCGKLNMH+N
Sbjct: 6   TAAASATGKLLVLLLLGLTAPAAALAGYIEALA-ANAGTGFAVAEPQIAVFCGKLNMHVN 64

Query: 335 VQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCK 514
           +Q GKWE DP+GTK C GTKE +LQYCQE+YPELQITNV+EAN+PV++ NWC+R +KQCK
Sbjct: 65  IQTGKWEPDPTGTKKCFGTKEEVLQYCQEMYPELQITNVMEANEPVSVDNWCRRDKKQCK 124

Query: 515 THTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLH 694
             TH+V+P++CLVGEFVSD LLVP+KC+F H+E+M+VCE H HWHTV KE C  +   L+
Sbjct: 125 --THVVVPFKCLVGEFVSDVLLVPEKCQFSHKEQMEVCENHQHWHTVVKEACLAQGMTLY 182

Query: 695 DYGMLLPCGIDKFRGVEFVCCP 760
            YGMLLPCG+D+F G E+VCCP
Sbjct: 183 RYGMLLPCGVDRFHGTEYVCCP 204


>ref|XP_856781.1| PREDICTED: similar to Amyloid-like protein 2 precursor (Amyloid
            protein homolog) (APPH) (CDEI-box binding protein)
            (CDEBP) isoform 24 [Canis familiaris].
          Length = 732

 Score =  448 bits (1153), Expect = e-125
 Identities = 239/465 (51%), Positives = 311/465 (66%), Gaps = 5/465 (1%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAA 1246
            CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC ++IP T  
Sbjct: 291  CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTMIPPTPL 350

Query: 1247 STPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKK 1426
             T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNLPKA+++
Sbjct: 351  PTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQ 409

Query: 1427 AVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRH 1606
             +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ PPRP  
Sbjct: 410  TLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHR 469

Query: 1607 VFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLY 1786
            +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI ER NQSLSLLY
Sbjct: 470  ILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLY 529

Query: 1787 NVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPV 1966
             VP VA+EIQ+E+DELLQ+++       A+M          D    S++ET   V    V
Sbjct: 530  KVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVDVR---V 569

Query: 1967 NGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARP----AADRGLTTRPGSGLTNIKTEE 2134
            + E S D++ P+HPF     P+  ENE      +      A+  +         N+  +E
Sbjct: 570  SSEES-DEIPPFHPF--HPFPSLPENEGSGAGEQDGGLIGAEEKVINSKNKVDENMVIDE 626

Query: 2135 ISEVK-MDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXXK 2311
              +VK M        G E   + +    ED   +  A+IGL                  +
Sbjct: 627  TLDVKEMIFNAERVGGLEAEPESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLR 686

Query: 2312 KKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 2446
            K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 687  KRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 731



 Score =  267 bits (682), Expect = 5e-71
 Identities = 121/202 (59%), Positives = 155/202 (76%), Gaps = 3/202 (1%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEVPTDGNAGL---LAEPQVAMFCGKLNMHMN 334
           ++A  A  ++ +L  L L   AA  A  +E     NAG    +AEPQ+A+FCGKLNMH+N
Sbjct: 6   TAAASATGKLLVLLLLGLTAPAAALAGYIEALA-ANAGTGFAVAEPQIAVFCGKLNMHVN 64

Query: 335 VQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCK 514
           +Q GKWE DP+GTK C GTKE +LQYCQE+YPELQITNV+EAN+PV++ NWC+R +KQCK
Sbjct: 65  IQTGKWEPDPTGTKKCFGTKEEVLQYCQEMYPELQITNVMEANEPVSVDNWCRRDKKQCK 124

Query: 515 THTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLH 694
             TH+V+P++CLVGEFVSD LLVP+KC+F H+E+M+VCE H HWHTV KE C  +   L+
Sbjct: 125 --THVVVPFKCLVGEFVSDVLLVPEKCQFSHKEQMEVCENHQHWHTVVKEACLAQGMTLY 182

Query: 695 DYGMLLPCGIDKFRGVEFVCCP 760
            YGMLLPCG+D+F G E+VCCP
Sbjct: 183 RYGMLLPCGVDRFHGTEYVCCP 204


>ref|XP_855958.1| PREDICTED: similar to Amyloid-like protein 2 precursor (Amyloid
            protein homolog) (APPH) (CDEI-box binding protein)
            (CDEBP) isoform 4 [Canis familiaris].
          Length = 751

 Score =  448 bits (1153), Expect = e-125
 Identities = 239/465 (51%), Positives = 311/465 (66%), Gaps = 5/465 (1%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAA 1246
            CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC ++IP T  
Sbjct: 310  CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTMIPPTPL 369

Query: 1247 STPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKK 1426
             T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNLPKA+++
Sbjct: 370  PTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQ 428

Query: 1427 AVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRH 1606
             +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ PPRP  
Sbjct: 429  TLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHR 488

Query: 1607 VFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLY 1786
            +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI ER NQSLSLLY
Sbjct: 489  ILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLY 548

Query: 1787 NVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPV 1966
             VP VA+EIQ+E+DELLQ+++       A+M          D    S++ET   V    V
Sbjct: 549  KVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVDVR---V 588

Query: 1967 NGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARP----AADRGLTTRPGSGLTNIKTEE 2134
            + E S D++ P+HPF     P+  ENE      +      A+  +         N+  +E
Sbjct: 589  SSEES-DEIPPFHPF--HPFPSLPENEGSGAGEQDGGLIGAEEKVINSKNKVDENMVIDE 645

Query: 2135 ISEVK-MDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXXK 2311
              +VK M        G E   + +    ED   +  A+IGL                  +
Sbjct: 646  TLDVKEMIFNAERVGGLEAEPESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLR 705

Query: 2312 KKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 2446
            K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 706  KRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 750



 Score =  267 bits (682), Expect = 5e-71
 Identities = 121/202 (59%), Positives = 155/202 (76%), Gaps = 3/202 (1%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEVPTDGNAGL---LAEPQVAMFCGKLNMHMN 334
           ++A  A  ++ +L  L L   AA  A  +E     NAG    +AEPQ+A+FCGKLNMH+N
Sbjct: 6   TAAASATGKLLVLLLLGLTAPAAALAGYIEALA-ANAGTGFAVAEPQIAVFCGKLNMHVN 64

Query: 335 VQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCK 514
           +Q GKWE DP+GTK C GTKE +LQYCQE+YPELQITNV+EAN+PV++ NWC+R +KQCK
Sbjct: 65  IQTGKWEPDPTGTKKCFGTKEEVLQYCQEMYPELQITNVMEANEPVSVDNWCRRDKKQCK 124

Query: 515 THTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLH 694
             TH+V+P++CLVGEFVSD LLVP+KC+F H+E+M+VCE H HWHTV KE C  +   L+
Sbjct: 125 --THVVVPFKCLVGEFVSDVLLVPEKCQFSHKEQMEVCENHQHWHTVVKEACLAQGMTLY 182

Query: 695 DYGMLLPCGIDKFRGVEFVCCP 760
            YGMLLPCG+D+F G E+VCCP
Sbjct: 183 RYGMLLPCGVDRFHGTEYVCCP 204


>ref|XP_536530.2| PREDICTED: similar to Amyloid-like protein 2 precursor (Amyloid
            protein homolog) (APPH) (CDEI-box binding protein)
            (CDEBP) isoform 1 [Canis familiaris].
          Length = 763

 Score =  448 bits (1152), Expect = e-125
 Identities = 242/477 (50%), Positives = 318/477 (66%), Gaps = 17/477 (3%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAA 1246
            CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC ++IP T  
Sbjct: 310  CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTMIPPTPL 369

Query: 1247 STPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKK 1426
             T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNLPKA+++
Sbjct: 370  PTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQ 428

Query: 1427 AVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRH 1606
             +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ PPRP  
Sbjct: 429  TLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHR 488

Query: 1607 VFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLY 1786
            +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI ER NQSLSLLY
Sbjct: 489  ILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLY 548

Query: 1787 NVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPV 1966
             VP VA+EIQ+E+DELLQ+++       A+M          D    S++ET   V    V
Sbjct: 549  KVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVDVR---V 588

Query: 1967 NGEFSLDDLQPWHPF-GVDSVPANTENEVE---PVDARPAA---DRGL----------TT 2095
            + E S D++ P+HPF    S+P N + + E   P+     A   D GL            
Sbjct: 589  SSEES-DEIPPFHPFHPFPSLPENEDTQRELYHPMKKGSGAGEQDGGLIGAEEKVINSKN 647

Query: 2096 RPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXX 2275
            +    +   +T ++ E+  +AE     G E   + +    ED   +  A+IGL       
Sbjct: 648  KVDENMVIDETLDVKEMIFNAE--RVGGLEAEPESVGPLREDFSLSSSALIGLLVIAVAI 705

Query: 2276 XXXXXXXXXXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 2446
                       +K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 706  ATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 762



 Score =  267 bits (682), Expect = 5e-71
 Identities = 121/202 (59%), Positives = 155/202 (76%), Gaps = 3/202 (1%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEVPTDGNAGL---LAEPQVAMFCGKLNMHMN 334
           ++A  A  ++ +L  L L   AA  A  +E     NAG    +AEPQ+A+FCGKLNMH+N
Sbjct: 6   TAAASATGKLLVLLLLGLTAPAAALAGYIEALA-ANAGTGFAVAEPQIAVFCGKLNMHVN 64

Query: 335 VQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCK 514
           +Q GKWE DP+GTK C GTKE +LQYCQE+YPELQITNV+EAN+PV++ NWC+R +KQCK
Sbjct: 65  IQTGKWEPDPTGTKKCFGTKEEVLQYCQEMYPELQITNVMEANEPVSVDNWCRRDKKQCK 124

Query: 515 THTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLH 694
             TH+V+P++CLVGEFVSD LLVP+KC+F H+E+M+VCE H HWHTV KE C  +   L+
Sbjct: 125 --THVVVPFKCLVGEFVSDVLLVPEKCQFSHKEQMEVCENHQHWHTVVKEACLAQGMTLY 182

Query: 695 DYGMLLPCGIDKFRGVEFVCCP 760
            YGMLLPCG+D+F G E+VCCP
Sbjct: 183 RYGMLLPCGVDRFHGTEYVCCP 204


>ref|XP_856696.1| PREDICTED: similar to Amyloid-like protein 2 precursor (Amyloid
            protein homolog) (APPH) (CDEI-box binding protein)
            (CDEBP) isoform 22 [Canis familiaris].
          Length = 767

 Score =  448 bits (1152), Expect = e-125
 Identities = 242/477 (50%), Positives = 318/477 (66%), Gaps = 17/477 (3%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAA 1246
            CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC ++IP T  
Sbjct: 314  CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTMIPPTPL 373

Query: 1247 STPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKK 1426
             T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNLPKA+++
Sbjct: 374  PTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQ 432

Query: 1427 AVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRH 1606
             +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ PPRP  
Sbjct: 433  TLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHR 492

Query: 1607 VFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLY 1786
            +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI ER NQSLSLLY
Sbjct: 493  ILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLY 552

Query: 1787 NVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPV 1966
             VP VA+EIQ+E+DELLQ+++       A+M          D    S++ET   V    V
Sbjct: 553  KVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVDVR---V 592

Query: 1967 NGEFSLDDLQPWHPF-GVDSVPANTENEVE---PVDARPAA---DRGL----------TT 2095
            + E S D++ P+HPF    S+P N + + E   P+     A   D GL            
Sbjct: 593  SSEES-DEIPPFHPFHPFPSLPENEDTQRELYHPMKKGSGAGEQDGGLIGAEEKVINSKN 651

Query: 2096 RPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXX 2275
            +    +   +T ++ E+  +AE     G E   + +    ED   +  A+IGL       
Sbjct: 652  KVDENMVIDETLDVKEMIFNAE--RVGGLEAEPESVGPLREDFSLSSSALIGLLVIAVAI 709

Query: 2276 XXXXXXXXXXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 2446
                       +K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 710  ATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 766



 Score =  267 bits (682), Expect = 5e-71
 Identities = 121/202 (59%), Positives = 155/202 (76%), Gaps = 3/202 (1%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEVPTDGNAGL---LAEPQVAMFCGKLNMHMN 334
           ++A  A  ++ +L  L L   AA  A  +E     NAG    +AEPQ+A+FCGKLNMH+N
Sbjct: 6   TAAASATGKLLVLLLLGLTAPAAALAGYIEALA-ANAGTGFAVAEPQIAVFCGKLNMHVN 64

Query: 335 VQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCK 514
           +Q GKWE DP+GTK C GTKE +LQYCQE+YPELQITNV+EAN+PV++ NWC+R +KQCK
Sbjct: 65  IQTGKWEPDPTGTKKCFGTKEEVLQYCQEMYPELQITNVMEANEPVSVDNWCRRDKKQCK 124

Query: 515 THTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLH 694
             TH+V+P++CLVGEFVSD LLVP+KC+F H+E+M+VCE H HWHTV KE C  +   L+
Sbjct: 125 --THVVVPFKCLVGEFVSDVLLVPEKCQFSHKEQMEVCENHQHWHTVVKEACLAQGMTLY 182

Query: 695 DYGMLLPCGIDKFRGVEFVCCP 760
            YGMLLPCG+D+F G E+VCCP
Sbjct: 183 RYGMLLPCGVDRFHGTEYVCCP 204


>ref|XP_856617.1| PREDICTED: similar to Amyloid-like protein 2 precursor (Amyloid
            protein homolog) (APPH) (CDEI-box binding protein)
            (CDEBP) isoform 20 [Canis familiaris].
          Length = 768

 Score =  448 bits (1152), Expect = e-125
 Identities = 242/477 (50%), Positives = 318/477 (66%), Gaps = 17/477 (3%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAA 1246
            CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC ++IP T  
Sbjct: 315  CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTMIPPTPL 374

Query: 1247 STPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKK 1426
             T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNLPKA+++
Sbjct: 375  PTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQ 433

Query: 1427 AVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRH 1606
             +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ PPRP  
Sbjct: 434  TLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHR 493

Query: 1607 VFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLY 1786
            +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI ER NQSLSLLY
Sbjct: 494  ILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLY 553

Query: 1787 NVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPV 1966
             VP VA+EIQ+E+DELLQ+++       A+M          D    S++ET   V    V
Sbjct: 554  KVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVDVR---V 593

Query: 1967 NGEFSLDDLQPWHPF-GVDSVPANTENEVE---PVDARPAA---DRGL----------TT 2095
            + E S D++ P+HPF    S+P N + + E   P+     A   D GL            
Sbjct: 594  SSEES-DEIPPFHPFHPFPSLPENEDTQRELYHPMKKGSGAGEQDGGLIGAEEKVINSKN 652

Query: 2096 RPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXX 2275
            +    +   +T ++ E+  +AE     G E   + +    ED   +  A+IGL       
Sbjct: 653  KVDENMVIDETLDVKEMIFNAE--RVGGLEAEPESVGPLREDFSLSSSALIGLLVIAVAI 710

Query: 2276 XXXXXXXXXXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 2446
                       +K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 711  ATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 767



 Score =  267 bits (682), Expect = 5e-71
 Identities = 121/202 (59%), Positives = 155/202 (76%), Gaps = 3/202 (1%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEVPTDGNAGL---LAEPQVAMFCGKLNMHMN 334
           ++A  A  ++ +L  L L   AA  A  +E     NAG    +AEPQ+A+FCGKLNMH+N
Sbjct: 6   TAAASATGKLLVLLLLGLTAPAAALAGYIEALA-ANAGTGFAVAEPQIAVFCGKLNMHVN 64

Query: 335 VQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCK 514
           +Q GKWE DP+GTK C GTKE +LQYCQE+YPELQITNV+EAN+PV++ NWC+R +KQCK
Sbjct: 65  IQTGKWEPDPTGTKKCFGTKEEVLQYCQEMYPELQITNVMEANEPVSVDNWCRRDKKQCK 124

Query: 515 THTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLH 694
             TH+V+P++CLVGEFVSD LLVP+KC+F H+E+M+VCE H HWHTV KE C  +   L+
Sbjct: 125 --THVVVPFKCLVGEFVSDVLLVPEKCQFSHKEQMEVCENHQHWHTVVKEACLAQGMTLY 182

Query: 695 DYGMLLPCGIDKFRGVEFVCCP 760
            YGMLLPCG+D+F G E+VCCP
Sbjct: 183 RYGMLLPCGVDRFHGTEYVCCP 204


>ref|XP_856451.1| PREDICTED: similar to Amyloid-like protein 2 precursor (Amyloid
            protein homolog) (APPH) (CDEI-box binding protein)
            (CDEBP) isoform 16 [Canis familiaris].
          Length = 764

 Score =  443 bits (1139), Expect = e-124
 Identities = 241/478 (50%), Positives = 318/478 (66%), Gaps = 18/478 (3%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSV-IPTTA 1243
            CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC ++ +P T 
Sbjct: 310  CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTMTVPPTP 369

Query: 1244 ASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADK 1423
              T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNLPKA++
Sbjct: 370  LPTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAER 428

Query: 1424 KAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPR 1603
            + +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ PPRP 
Sbjct: 429  QTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPH 488

Query: 1604 HVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLL 1783
             +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI ER NQSLSLL
Sbjct: 489  RILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLL 548

Query: 1784 YNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLP 1963
            Y VP VA+EIQ+E+DELLQ+++       A+M          D    S++ET   V    
Sbjct: 549  YKVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVDVR--- 588

Query: 1964 VNGEFSLDDLQPWHPF-GVDSVPANTENEVE---PVDARPAA---DRGL----------T 2092
            V+ E S D++ P+HPF    S+P N + + E   P+     A   D GL           
Sbjct: 589  VSSEES-DEIPPFHPFHPFPSLPENEDTQRELYHPMKKGSGAGEQDGGLIGAEEKVINSK 647

Query: 2093 TRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXX 2272
             +    +   +T ++ E+  +AE     G E   + +    ED   +  A+IGL      
Sbjct: 648  NKVDENMVIDETLDVKEMIFNAE--RVGGLEAEPESVGPLREDFSLSSSALIGLLVIAVA 705

Query: 2273 XXXXXXXXXXXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 2446
                        +K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 706  IATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 763



 Score =  267 bits (682), Expect = 5e-71
 Identities = 121/202 (59%), Positives = 155/202 (76%), Gaps = 3/202 (1%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEVPTDGNAGL---LAEPQVAMFCGKLNMHMN 334
           ++A  A  ++ +L  L L   AA  A  +E     NAG    +AEPQ+A+FCGKLNMH+N
Sbjct: 6   TAAASATGKLLVLLLLGLTAPAAALAGYIEALA-ANAGTGFAVAEPQIAVFCGKLNMHVN 64

Query: 335 VQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCK 514
           +Q GKWE DP+GTK C GTKE +LQYCQE+YPELQITNV+EAN+PV++ NWC+R +KQCK
Sbjct: 65  IQTGKWEPDPTGTKKCFGTKEEVLQYCQEMYPELQITNVMEANEPVSVDNWCRRDKKQCK 124

Query: 515 THTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLH 694
             TH+V+P++CLVGEFVSD LLVP+KC+F H+E+M+VCE H HWHTV KE C  +   L+
Sbjct: 125 --THVVVPFKCLVGEFVSDVLLVPEKCQFSHKEQMEVCENHQHWHTVVKEACLAQGMTLY 182

Query: 695 DYGMLLPCGIDKFRGVEFVCCP 760
            YGMLLPCG+D+F G E+VCCP
Sbjct: 183 RYGMLLPCGVDRFHGTEYVCCP 204


>ref|XP_856494.1| PREDICTED: similar to Amyloid-like protein 2 precursor (Amyloid
            protein homolog) (APPH) (CDEI-box binding protein)
            (CDEBP) isoform 17 [Canis familiaris].
          Length = 773

 Score =  439 bits (1130), Expect = e-123
 Identities = 241/487 (49%), Positives = 318/487 (65%), Gaps = 27/487 (5%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSV------ 1228
            CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC ++      
Sbjct: 310  CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTMSKEPLL 369

Query: 1229 ----IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQ 1396
                +P T   T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE Q
Sbjct: 370  SFVSVPPTPLPTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQ 428

Query: 1397 AKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITA 1576
            AKNLPKA+++ +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ A
Sbjct: 429  AKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAA 488

Query: 1577 LQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE 1756
            LQ+ PPRP  +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI E
Sbjct: 489  LQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEE 548

Query: 1757 RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTE 1936
            R NQSLSLLY VP VA+EIQ+E+DELLQ+++       A+M          D    S++E
Sbjct: 549  RRNQSLSLLYKVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISE 591

Query: 1937 TKTTVELLPVNGEFSLDDLQPWHPF-GVDSVPANTENEVE---PVDARPAA---DRGL-- 2089
            T   V    V+ E S D++ P+HPF    S+P N + + E   P+     A   D GL  
Sbjct: 592  TPVDVR---VSSEES-DEIPPFHPFHPFPSLPENEDTQRELYHPMKKGSGAGEQDGGLIG 647

Query: 2090 --------TTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAI 2245
                      +    +   +T ++ E+  +AE     G E   + +    ED   +  A+
Sbjct: 648  AEEKVINSKNKVDENMVIDETLDVKEMIFNAE--RVGGLEAEPESVGPLREDFSLSSSAL 705

Query: 2246 IGLXXXXXXXXXXXXXXXXXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTY 2425
            IGL                  +K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTY
Sbjct: 706  IGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTY 765

Query: 2426 KFFEQMQ 2446
            K+ EQMQ
Sbjct: 766  KYLEQMQ 772



 Score =  267 bits (682), Expect = 5e-71
 Identities = 121/202 (59%), Positives = 155/202 (76%), Gaps = 3/202 (1%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEVPTDGNAGL---LAEPQVAMFCGKLNMHMN 334
           ++A  A  ++ +L  L L   AA  A  +E     NAG    +AEPQ+A+FCGKLNMH+N
Sbjct: 6   TAAASATGKLLVLLLLGLTAPAAALAGYIEALA-ANAGTGFAVAEPQIAVFCGKLNMHVN 64

Query: 335 VQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCK 514
           +Q GKWE DP+GTK C GTKE +LQYCQE+YPELQITNV+EAN+PV++ NWC+R +KQCK
Sbjct: 65  IQTGKWEPDPTGTKKCFGTKEEVLQYCQEMYPELQITNVMEANEPVSVDNWCRRDKKQCK 124

Query: 515 THTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLH 694
             TH+V+P++CLVGEFVSD LLVP+KC+F H+E+M+VCE H HWHTV KE C  +   L+
Sbjct: 125 --THVVVPFKCLVGEFVSDVLLVPEKCQFSHKEQMEVCENHQHWHTVVKEACLAQGMTLY 182

Query: 695 DYGMLLPCGIDKFRGVEFVCCP 760
            YGMLLPCG+D+F G E+VCCP
Sbjct: 183 RYGMLLPCGVDRFHGTEYVCCP 204


>ref|XP_856283.1| PREDICTED: similar to Amyloid-like protein 2 precursor (Amyloid
            protein homolog) (APPH) (CDEI-box binding protein)
            (CDEBP) isoform 12 [Canis familiaris].
          Length = 777

 Score =  439 bits (1130), Expect = e-123
 Identities = 241/487 (49%), Positives = 318/487 (65%), Gaps = 27/487 (5%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSV------ 1228
            CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC ++      
Sbjct: 314  CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTMSKEPLL 373

Query: 1229 ----IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQ 1396
                +P T   T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE Q
Sbjct: 374  SFVSVPPTPLPTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQ 432

Query: 1397 AKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITA 1576
            AKNLPKA+++ +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ A
Sbjct: 433  AKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAA 492

Query: 1577 LQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE 1756
            LQ+ PPRP  +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI E
Sbjct: 493  LQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEE 552

Query: 1757 RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTE 1936
            R NQSLSLLY VP VA+EIQ+E+DELLQ+++       A+M          D    S++E
Sbjct: 553  RRNQSLSLLYKVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISE 595

Query: 1937 TKTTVELLPVNGEFSLDDLQPWHPF-GVDSVPANTENEVE---PVDARPAA---DRGL-- 2089
            T   V    V+ E S D++ P+HPF    S+P N + + E   P+     A   D GL  
Sbjct: 596  TPVDVR---VSSEES-DEIPPFHPFHPFPSLPENEDTQRELYHPMKKGSGAGEQDGGLIG 651

Query: 2090 --------TTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAI 2245
                      +    +   +T ++ E+  +AE     G E   + +    ED   +  A+
Sbjct: 652  AEEKVINSKNKVDENMVIDETLDVKEMIFNAE--RVGGLEAEPESVGPLREDFSLSSSAL 709

Query: 2246 IGLXXXXXXXXXXXXXXXXXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTY 2425
            IGL                  +K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTY
Sbjct: 710  IGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTY 769

Query: 2426 KFFEQMQ 2446
            K+ EQMQ
Sbjct: 770  KYLEQMQ 776



 Score =  267 bits (682), Expect = 5e-71
 Identities = 121/202 (59%), Positives = 155/202 (76%), Gaps = 3/202 (1%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEVPTDGNAGL---LAEPQVAMFCGKLNMHMN 334
           ++A  A  ++ +L  L L   AA  A  +E     NAG    +AEPQ+A+FCGKLNMH+N
Sbjct: 6   TAAASATGKLLVLLLLGLTAPAAALAGYIEALA-ANAGTGFAVAEPQIAVFCGKLNMHVN 64

Query: 335 VQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCK 514
           +Q GKWE DP+GTK C GTKE +LQYCQE+YPELQITNV+EAN+PV++ NWC+R +KQCK
Sbjct: 65  IQTGKWEPDPTGTKKCFGTKEEVLQYCQEMYPELQITNVMEANEPVSVDNWCRRDKKQCK 124

Query: 515 THTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLH 694
             TH+V+P++CLVGEFVSD LLVP+KC+F H+E+M+VCE H HWHTV KE C  +   L+
Sbjct: 125 --THVVVPFKCLVGEFVSDVLLVPEKCQFSHKEQMEVCENHQHWHTVVKEACLAQGMTLY 182

Query: 695 DYGMLLPCGIDKFRGVEFVCCP 760
            YGMLLPCG+D+F G E+VCCP
Sbjct: 183 RYGMLLPCGVDRFHGTEYVCCP 204


  Database: RefSeq49_CP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,874,504
  Number of sequences in database:  33,336
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33336
Number of Hits to DB: 118,978,207
Number of extensions: 3106046
Number of successful extensions: 12616
Number of sequences better than 1.0e-05: 41
Number of HSP's gapped: 12439
Number of HSP's successfully gapped: 76
Length of query: 1049
Length of database: 18,874,504
Length adjustment: 113
Effective length of query: 936
Effective length of database: 15,107,536
Effective search space: 14140653696
Effective search space used: 14140653696
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BFLT1_0085_G08
         (3148 letters)

Database: RefSeq49_HP.fasta 
           32,964 sequences; 18,297,164 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_958816.1| amyloid beta A4 protein isoform b precursor [Ho...  1306   0.0  
Alignment   gi|NP_000475.1| amyloid beta A4 protein isoform a precursor [Ho...  1294   0.0  
Alignment   gi|NP_001129488.1| amyloid beta A4 protein isoform d [Homo sapi...  1272   0.0  
Alignment   gi|NP_001191231.1| amyloid beta A4 protein isoform i precursor ...  1259   0.0  
Alignment   gi|NP_001191230.1| amyloid beta A4 protein isoform h precursor ...  1247   0.0  
Alignment   gi|NP_001129602.1| amyloid beta A4 protein isoform f precursor ...  1148   0.0  
Alignment   gi|NP_001129603.1| amyloid beta A4 protein isoform g [Homo sapi...   766   0.0  
Alignment   gi|NP_958817.1| amyloid beta A4 protein isoform c precursor [Ho...   766   0.0  
Alignment   gi|NP_001129601.1| amyloid beta A4 protein isoform e precursor ...   766   0.0  
Alignment   gi|NP_001191232.1| amyloid beta A4 protein isoform j precursor ...   719   0.0  

>ref|NP_958816.1| amyloid beta A4 protein isoform b precursor [Homo sapiens].
          Length = 751

 Score = 1306 bits (3380), Expect = 0.0
 Identities = 648/751 (86%), Positives = 652/751 (86%)
 Frame = +2

Query: 197  MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 376
            MLPGLAL+LLAAWTARALEVPTDGNAGLLAEPQ+AMFCG+LNMHMNVQNGKW+SDPSGTK
Sbjct: 1    MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTK 60

Query: 377  TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 556
            TCI TKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR RKQCKTH H VIPYRCLVG
Sbjct: 61   TCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVG 120

Query: 557  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 736
            EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
Sbjct: 121  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 180

Query: 737  GVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXX 916
            GVEFVCCPL                  VWWGGADTDYADGSEDKVV              
Sbjct: 181  GVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEE 240

Query: 917  XXXXXXXXXXXXXXXXXXXXPYEEATERXXXXXXXXXXXXXXXXXXXXXXCSEQAETGPC 1096
                                PYEEATER                      CSEQAETGPC
Sbjct: 241  EADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPC 300

Query: 1097 RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAASTPDAVDKYL 1276
            RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS IPTTAASTPDAVDKYL
Sbjct: 301  RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYL 360

Query: 1277 ETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKV 1456
            ETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKV
Sbjct: 361  ETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKV 420

Query: 1457 ESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVR 1636
            ESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVR
Sbjct: 421  ESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVR 480

Query: 1637 AEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQ 1816
            AEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQ
Sbjct: 481  AEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQ 540

Query: 1817 DEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQ 1996
            DEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQ
Sbjct: 541  DEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQ 600

Query: 1997 PWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDS 2176
            PWH FG DSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDS
Sbjct: 601  PWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDS 660

Query: 2177 GYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXXKKKQYTSIHHGVVEVD 2356
            GYEVHHQKLVFFAEDVGSNKGAIIGL                  KKKQYTSIHHGVVEVD
Sbjct: 661  GYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVD 720

Query: 2357 AAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
            AAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 721  AAVTPEERHLSKMQQNGYENPTYKFFEQMQN 751


>ref|NP_000475.1| amyloid beta A4 protein isoform a precursor [Homo sapiens].
          Length = 770

 Score = 1294 bits (3348), Expect = 0.0
 Identities = 647/770 (84%), Positives = 652/770 (84%), Gaps = 19/770 (2%)
 Frame = +2

Query: 197  MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 376
            MLPGLAL+LLAAWTARALEVPTDGNAGLLAEPQ+AMFCG+LNMHMNVQNGKW+SDPSGTK
Sbjct: 1    MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTK 60

Query: 377  TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 556
            TCI TKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR RKQCKTH H VIPYRCLVG
Sbjct: 61   TCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVG 120

Query: 557  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 736
            EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
Sbjct: 121  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 180

Query: 737  GVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXX 916
            GVEFVCCPL                  VWWGGADTDYADGSEDKVV              
Sbjct: 181  GVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEE 240

Query: 917  XXXXXXXXXXXXXXXXXXXXPYEEATERXXXXXXXXXXXXXXXXXXXXXXCSEQAETGPC 1096
                                PYEEATER                      CSEQAETGPC
Sbjct: 241  EADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPC 300

Query: 1097 RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSV---------------- 1228
            RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS                 
Sbjct: 301  RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARD 360

Query: 1229 ---IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA 1399
               +PTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA
Sbjct: 361  PVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA 420

Query: 1400 KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL 1579
            KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL
Sbjct: 421  KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL 480

Query: 1580 QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER 1759
            QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER
Sbjct: 481  QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER 540

Query: 1760 MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET 1939
            MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET
Sbjct: 541  MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET 600

Query: 1940 KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTN 2119
            KTTVELLPVNGEFSLDDLQPWH FG DSVPANTENEVEPVDARPAADRGLTTRPGSGLTN
Sbjct: 601  KTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTN 660

Query: 2120 IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXX 2299
            IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGL               
Sbjct: 661  IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITL 720

Query: 2300 XXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
               KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 721  VMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 770


>ref|NP_001129488.1| amyloid beta A4 protein isoform d [Homo sapiens].
          Length = 746

 Score = 1272 bits (3291), Expect = 0.0
 Identities = 630/732 (86%), Positives = 633/732 (86%)
 Frame = +2

Query: 254  VPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTKTCIGTKEGILQYCQEVYPE 433
            VPTDGNAGLLAEPQ+AMFCG+LNMHMNVQNGKW+SDPSGTKTCI TKEGILQYCQEVYPE
Sbjct: 15   VPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPE 74

Query: 434  LQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVGEFVSDALLVPDKCKFLHQE 613
            LQITNVVEANQPVTIQNWCKR RKQCKTH H VIPYRCLVGEFVSDALLVPDKCKFLHQE
Sbjct: 75   LQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQE 134

Query: 614  RMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLXXXXXXXXXX 793
            RMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPL          
Sbjct: 135  RMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSA 194

Query: 794  XXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 973
                    VWWGGADTDYADGSEDKVV                                 
Sbjct: 195  DAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAE 254

Query: 974  XPYEEATERXXXXXXXXXXXXXXXXXXXXXXCSEQAETGPCRAMISRWYFDVTEGKCAPF 1153
             PYEEATER                      CSEQAETGPCRAMISRWYFDVTEGKCAPF
Sbjct: 255  EPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPF 314

Query: 1154 FYGGCGGNRNNFDTEEYCMAVCGSVIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERL 1333
            FYGGCGGNRNNFDTEEYCMAVCGS IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERL
Sbjct: 315  FYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERL 374

Query: 1334 EAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHM 1513
            EAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHM
Sbjct: 375  EAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHM 434

Query: 1514 ARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMV 1693
            ARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMV
Sbjct: 435  ARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMV 494

Query: 1694 DPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLA 1873
            DPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLA
Sbjct: 495  DPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLA 554

Query: 1874 NMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVE 2053
            NMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWH FG DSVPANTENEVE
Sbjct: 555  NMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVE 614

Query: 2054 PVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSN 2233
            PVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSN
Sbjct: 615  PVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSN 674

Query: 2234 KGAIIGLXXXXXXXXXXXXXXXXXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYE 2413
            KGAIIGL                  KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYE
Sbjct: 675  KGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYE 734

Query: 2414 NPTYKFFEQMQN 2449
            NPTYKFFEQMQN
Sbjct: 735  NPTYKFFEQMQN 746


>ref|NP_001191231.1| amyloid beta A4 protein isoform i precursor [Homo sapiens].
          Length = 733

 Score = 1259 bits (3258), Expect = 0.0
 Identities = 630/751 (83%), Positives = 634/751 (84%)
 Frame = +2

Query: 197  MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 376
            MLPGLAL+LLAAWTARALEVPTDGNAGLLAEPQ+AMFCG+LNMHMNVQNGKW+SDPSGTK
Sbjct: 1    MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTK 60

Query: 377  TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 556
            TCI TKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR RKQCKTH H VIPYRCLVG
Sbjct: 61   TCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVG 120

Query: 557  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 736
            EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
Sbjct: 121  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 180

Query: 737  GVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXX 916
            GVEFVCCPL                  VWWGGADTDYADGSEDKVV              
Sbjct: 181  GVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEE 240

Query: 917  XXXXXXXXXXXXXXXXXXXXPYEEATERXXXXXXXXXXXXXXXXXXXXXXCSEQAETGPC 1096
                                PYEEATER                      CSEQAETGPC
Sbjct: 241  EADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPC 300

Query: 1097 RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAASTPDAVDKYL 1276
            RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS IPTTAASTPDAVDKYL
Sbjct: 301  RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYL 360

Query: 1277 ETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKV 1456
            ETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKV
Sbjct: 361  ETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKV 420

Query: 1457 ESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVR 1636
            ESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVR
Sbjct: 421  ESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVR 480

Query: 1637 AEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQ 1816
            AEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQ
Sbjct: 481  AEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQ 540

Query: 1817 DEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQ 1996
            DEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQ
Sbjct: 541  DEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQ 600

Query: 1997 PWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDS 2176
            PWH FG DSVPANTENE                  GSGLTNIKTEEISEVKMDAEFRHDS
Sbjct: 601  PWHSFGADSVPANTENE------------------GSGLTNIKTEEISEVKMDAEFRHDS 642

Query: 2177 GYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXXKKKQYTSIHHGVVEVD 2356
            GYEVHHQKLVFFAEDVGSNKGAIIGL                  KKKQYTSIHHGVVEVD
Sbjct: 643  GYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVD 702

Query: 2357 AAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
            AAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 703  AAVTPEERHLSKMQQNGYENPTYKFFEQMQN 733


>ref|NP_001191230.1| amyloid beta A4 protein isoform h precursor [Homo sapiens].
          Length = 752

 Score = 1247 bits (3226), Expect = 0.0
 Identities = 629/770 (81%), Positives = 634/770 (82%), Gaps = 19/770 (2%)
 Frame = +2

Query: 197  MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 376
            MLPGLAL+LLAAWTARALEVPTDGNAGLLAEPQ+AMFCG+LNMHMNVQNGKW+SDPSGTK
Sbjct: 1    MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTK 60

Query: 377  TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 556
            TCI TKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR RKQCKTH H VIPYRCLVG
Sbjct: 61   TCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVG 120

Query: 557  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 736
            EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
Sbjct: 121  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 180

Query: 737  GVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXX 916
            GVEFVCCPL                  VWWGGADTDYADGSEDKVV              
Sbjct: 181  GVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEE 240

Query: 917  XXXXXXXXXXXXXXXXXXXXPYEEATERXXXXXXXXXXXXXXXXXXXXXXCSEQAETGPC 1096
                                PYEEATER                      CSEQAETGPC
Sbjct: 241  EADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPC 300

Query: 1097 RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSV---------------- 1228
            RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS                 
Sbjct: 301  RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARD 360

Query: 1229 ---IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA 1399
               +PTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA
Sbjct: 361  PVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA 420

Query: 1400 KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL 1579
            KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL
Sbjct: 421  KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL 480

Query: 1580 QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER 1759
            QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER
Sbjct: 481  QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER 540

Query: 1760 MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET 1939
            MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET
Sbjct: 541  MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET 600

Query: 1940 KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTN 2119
            KTTVELLPVNGEFSLDDLQPWH FG DSVPANTENE                  GSGLTN
Sbjct: 601  KTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENE------------------GSGLTN 642

Query: 2120 IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXX 2299
            IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGL               
Sbjct: 643  IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITL 702

Query: 2300 XXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
               KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 703  VMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 752


>ref|NP_001129602.1| amyloid beta A4 protein isoform f precursor [Homo sapiens].
          Length = 714

 Score = 1148 bits (2969), Expect = 0.0
 Identities = 578/696 (83%), Positives = 579/696 (83%), Gaps = 19/696 (2%)
 Frame = +2

Query: 419  EVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVGEFVSDALLVPDKCK 598
            EVYPELQITNVVEANQPVTIQNWCKR RKQCKTH H VIPYRCLVGEFVSDALLVPDKCK
Sbjct: 19   EVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCK 78

Query: 599  FLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLXXXXX 778
            FLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPL     
Sbjct: 79   FLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD 138

Query: 779  XXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXXXXXXXXXXXXXXXX 958
                         VWWGGADTDYADGSEDKVV                            
Sbjct: 139  NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEV 198

Query: 959  XXXXXXPYEEATERXXXXXXXXXXXXXXXXXXXXXXCSEQAETGPCRAMISRWYFDVTEG 1138
                  PYEEATER                      CSEQAETGPCRAMISRWYFDVTEG
Sbjct: 199  EEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEG 258

Query: 1139 KCAPFFYGGCGGNRNNFDTEEYCMAVCGSV-------------------IPTTAASTPDA 1261
            KCAPFFYGGCGGNRNNFDTEEYCMAVCGS                    +PTTAASTPDA
Sbjct: 259  KCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA 318

Query: 1262 VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQH 1441
            VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQH
Sbjct: 319  VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQH 378

Query: 1442 FQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNML 1621
            FQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNML
Sbjct: 379  FQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNML 438

Query: 1622 KKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV 1801
            KKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
Sbjct: 439  KKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV 498

Query: 1802 AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFS 1981
            AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFS
Sbjct: 499  AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFS 558

Query: 1982 LDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAE 2161
            LDDLQPWH FG DSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAE
Sbjct: 559  LDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAE 618

Query: 2162 FRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXXKKKQYTSIHHG 2341
            FRHDSGYEVHHQKLVFFAEDVGSNKGAIIGL                  KKKQYTSIHHG
Sbjct: 619  FRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG 678

Query: 2342 VVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
            VVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 679  VVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 714


>ref|NP_001129603.1| amyloid beta A4 protein isoform g [Homo sapiens].
          Length = 660

 Score =  766 bits (1979), Expect = 0.0
 Identities = 386/407 (94%), Positives = 387/407 (95%)
 Frame = +2

Query: 1229 IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 1408
            +PTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL
Sbjct: 254  VPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 313

Query: 1409 PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 1588
            PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
Sbjct: 314  PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 373

Query: 1589 PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 1768
            PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ
Sbjct: 374  PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 433

Query: 1769 SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 1948
            SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT
Sbjct: 434  SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 493

Query: 1949 VELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT 2128
            VELLPVNGEFSLDDLQPWH FG DSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
Sbjct: 494  VELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT 553

Query: 2129 EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXX 2308
            EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGL                  
Sbjct: 554  EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVML 613

Query: 2309 KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
            KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 614  KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 660



 Score =  367 bits (942), Expect = e-101
 Identities = 175/233 (75%), Positives = 177/233 (75%)
 Frame = +2

Query: 302  MFCGKLNMHMNVQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQ 481
            MFCG+LNMHMNVQNGKW+SDPSGTKTCI TKEGILQYCQEVYPELQITNVVEANQPVTIQ
Sbjct: 1    MFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQ 60

Query: 482  NWCKRSRKQCKTHTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAK 661
            NWCKR RKQCKTH H VIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAK
Sbjct: 61   NWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAK 120

Query: 662  ETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADT 841
            ETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPL                  VWWGGADT
Sbjct: 121  ETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADT 180

Query: 842  DYADGSEDKVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPYEEATER 1000
            DYADGSEDKVV                                  PYEEATER
Sbjct: 181  DYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATER 233


>ref|NP_958817.1| amyloid beta A4 protein isoform c precursor [Homo sapiens].
          Length = 695

 Score =  766 bits (1979), Expect = 0.0
 Identities = 386/407 (94%), Positives = 387/407 (95%)
 Frame = +2

Query: 1229 IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 1408
            +PTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL
Sbjct: 289  VPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 348

Query: 1409 PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 1588
            PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
Sbjct: 349  PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 408

Query: 1589 PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 1768
            PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ
Sbjct: 409  PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 468

Query: 1769 SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 1948
            SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT
Sbjct: 469  SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 528

Query: 1949 VELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT 2128
            VELLPVNGEFSLDDLQPWH FG DSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
Sbjct: 529  VELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT 588

Query: 2129 EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXX 2308
            EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGL                  
Sbjct: 589  EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVML 648

Query: 2309 KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
            KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 649  KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 695



 Score =  432 bits (1111), Expect = e-121
 Identities = 208/268 (77%), Positives = 212/268 (79%)
 Frame = +2

Query: 197  MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 376
            MLPGLAL+LLAAWTARALEVPTDGNAGLLAEPQ+AMFCG+LNMHMNVQNGKW+SDPSGTK
Sbjct: 1    MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTK 60

Query: 377  TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 556
            TCI TKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR RKQCKTH H VIPYRCLVG
Sbjct: 61   TCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVG 120

Query: 557  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 736
            EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
Sbjct: 121  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 180

Query: 737  GVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXX 916
            GVEFVCCPL                  VWWGGADTDYADGSEDKVV              
Sbjct: 181  GVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEE 240

Query: 917  XXXXXXXXXXXXXXXXXXXXPYEEATER 1000
                                PYEEATER
Sbjct: 241  EADDDEDDEDGDEVEEEAEEPYEEATER 268


>ref|NP_001129601.1| amyloid beta A4 protein isoform e precursor [Homo sapiens].
          Length = 639

 Score =  766 bits (1979), Expect = 0.0
 Identities = 386/407 (94%), Positives = 387/407 (95%)
 Frame = +2

Query: 1229 IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 1408
            +PTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL
Sbjct: 233  VPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 292

Query: 1409 PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 1588
            PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
Sbjct: 293  PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 352

Query: 1589 PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 1768
            PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ
Sbjct: 353  PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 412

Query: 1769 SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 1948
            SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT
Sbjct: 413  SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 472

Query: 1949 VELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT 2128
            VELLPVNGEFSLDDLQPWH FG DSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
Sbjct: 473  VELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT 532

Query: 2129 EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXX 2308
            EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGL                  
Sbjct: 533  EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVML 592

Query: 2309 KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
            KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 593  KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 639



 Score =  286 bits (732), Expect = 8e-77
 Identities = 139/194 (71%), Positives = 139/194 (71%)
 Frame = +2

Query: 419  EVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVGEFVSDALLVPDKCK 598
            EVYPELQITNVVEANQPVTIQNWCKR RKQCKTH H VIPYRCLVGEFVSDALLVPDKCK
Sbjct: 19   EVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCK 78

Query: 599  FLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLXXXXX 778
            FLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPL     
Sbjct: 79   FLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD 138

Query: 779  XXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXXXXXXXXXXXXXXXX 958
                         VWWGGADTDYADGSEDKVV                            
Sbjct: 139  NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEV 198

Query: 959  XXXXXXPYEEATER 1000
                  PYEEATER
Sbjct: 199  EEEAEEPYEEATER 212


>ref|NP_001191232.1| amyloid beta A4 protein isoform j precursor [Homo sapiens].
          Length = 677

 Score =  719 bits (1857), Expect = 0.0
 Identities = 368/407 (90%), Positives = 369/407 (90%)
 Frame = +2

Query: 1229 IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 1408
            +PTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL
Sbjct: 289  VPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 348

Query: 1409 PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 1588
            PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
Sbjct: 349  PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 408

Query: 1589 PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 1768
            PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ
Sbjct: 409  PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 468

Query: 1769 SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 1948
            SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT
Sbjct: 469  SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 528

Query: 1949 VELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT 2128
            VELLPVNGEFSLDDLQPWH FG DSVPANTENE                  GSGLTNIKT
Sbjct: 529  VELLPVNGEFSLDDLQPWHSFGADSVPANTENE------------------GSGLTNIKT 570

Query: 2129 EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXX 2308
            EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGL                  
Sbjct: 571  EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVML 630

Query: 2309 KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
            KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 631  KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 677



 Score =  432 bits (1111), Expect = e-121
 Identities = 208/268 (77%), Positives = 212/268 (79%)
 Frame = +2

Query: 197  MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 376
            MLPGLAL+LLAAWTARALEVPTDGNAGLLAEPQ+AMFCG+LNMHMNVQNGKW+SDPSGTK
Sbjct: 1    MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTK 60

Query: 377  TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 556
            TCI TKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR RKQCKTH H VIPYRCLVG
Sbjct: 61   TCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVG 120

Query: 557  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 736
            EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
Sbjct: 121  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 180

Query: 737  GVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXX 916
            GVEFVCCPL                  VWWGGADTDYADGSEDKVV              
Sbjct: 181  GVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEE 240

Query: 917  XXXXXXXXXXXXXXXXXXXXPYEEATER 1000
                                PYEEATER
Sbjct: 241  EADDDEDDEDGDEVEEEAEEPYEEATER 268


  Database: RefSeq49_HP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 18,297,164
  Number of sequences in database:  32,964
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 32964
Number of Hits to DB: 117,144,184
Number of extensions: 3072018
Number of successful extensions: 11927
Number of sequences better than 1.0e-05: 39
Number of HSP's gapped: 11756
Number of HSP's successfully gapped: 58
Length of query: 1049
Length of database: 18,297,164
Length adjustment: 113
Effective length of query: 936
Effective length of database: 14,572,232
Effective search space: 13639609152
Effective search space used: 13639609152
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BFLT1_0085_G08
         (3148 letters)

Database: RefSeq49_MP.fasta 
           30,036 sequences; 15,617,559 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_001185753.1| amyloid beta A4 protein isoform 3 precursor ...  1303   0.0  
Alignment   gi|NP_001185752.1| amyloid beta A4 protein isoform 1 precursor ...  1293   0.0  
Alignment   gi|NP_001185754.1| amyloid beta A4 protein isoform 5 precursor ...  1256   0.0  
Alignment   gi|NP_001185755.1| amyloid beta A4 protein isoform 6 precursor ...  1246   0.0  
Alignment   gi|NP_031497.2| amyloid beta A4 protein isoform 2 precursor [Mu...   762   0.0  
Alignment   gi|NP_001095925.1| amyloid-like protein 2 isoform a [Mus muscul...   442   e-124
Alignment   gi|NP_001095926.1| amyloid-like protein 2 isoform b [Mus muscul...   353   5e-97
Alignment   gi|NP_033821.1| amyloid-like protein 2 isoform c [Mus musculus].     352   1e-96
Alignment   gi|NP_031493.2| amyloid-like protein 1 [Mus musculus].               241   2e-63
Alignment   gi|NP_035594.1| kunitz-type protease inhibitor 2 isoform a [Mus...    69   3e-11

>ref|NP_001185753.1| amyloid beta A4 protein isoform 3 precursor [Mus musculus].
          Length = 751

 Score = 1303 bits (3373), Expect = 0.0
 Identities = 647/751 (86%), Positives = 650/751 (86%)
 Frame = +2

Query: 197  MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 376
            MLP LAL+LLAAWT RALEVPTDGNAGLLAEPQ+AMFCGKLNMHMNVQNGKWESDPSGTK
Sbjct: 1    MLPSLALLLLAAWTVRALEVPTDGNAGLLAEPQIAMFCGKLNMHMNVQNGKWESDPSGTK 60

Query: 377  TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 556
            TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR RKQCKTHTHIVIPYRCLVG
Sbjct: 61   TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHTHIVIPYRCLVG 120

Query: 557  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 736
            EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
Sbjct: 121  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 180

Query: 737  GVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXX 916
            GVEFVCCPL                  VWWGGADTDYADG EDKVV              
Sbjct: 181  GVEFVCCPLAEESDSVDSADAEEDDSDVWWGGADTDYADGGEDKVVEVAEEEEVADVEEE 240

Query: 917  XXXXXXXXXXXXXXXXXXXXPYEEATERXXXXXXXXXXXXXXXXXXXXXXCSEQAETGPC 1096
                                PYEEATER                      CSEQAETGPC
Sbjct: 241  EADDDEDVEDGDEVEEEAEEPYEEATERTTSTATTTTTTTESVEEVVREVCSEQAETGPC 300

Query: 1097 RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAASTPDAVDKYL 1276
            RAMISRWYFDVTEGKC PFFYGGCGGNRNNFDTEEYCMAVCGSV PTTAASTPDAVDKYL
Sbjct: 301  RAMISRWYFDVTEGKCVPFFYGGCGGNRNNFDTEEYCMAVCGSVFPTTAASTPDAVDKYL 360

Query: 1277 ETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKV 1456
            ETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKV
Sbjct: 361  ETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKV 420

Query: 1457 ESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVR 1636
            ESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRP HVFNMLKKYVR
Sbjct: 421  ESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPHHVFNMLKKYVR 480

Query: 1637 AEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQ 1816
            AEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQ
Sbjct: 481  AEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQ 540

Query: 1817 DEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQ 1996
            DEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQ
Sbjct: 541  DEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQ 600

Query: 1997 PWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDS 2176
            PWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEF HDS
Sbjct: 601  PWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFGHDS 660

Query: 2177 GYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXXKKKQYTSIHHGVVEVD 2356
            G+EV HQKLVFFAEDVGSNKGAIIGL                  KKKQYTSIHHGVVEVD
Sbjct: 661  GFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVD 720

Query: 2357 AAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
            AAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 721  AAVTPEERHLSKMQQNGYENPTYKFFEQMQN 751


>ref|NP_001185752.1| amyloid beta A4 protein isoform 1 precursor [Mus musculus].
          Length = 770

 Score = 1293 bits (3345), Expect = 0.0
 Identities = 647/770 (84%), Positives = 651/770 (84%), Gaps = 19/770 (2%)
 Frame = +2

Query: 197  MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 376
            MLP LAL+LLAAWT RALEVPTDGNAGLLAEPQ+AMFCGKLNMHMNVQNGKWESDPSGTK
Sbjct: 1    MLPSLALLLLAAWTVRALEVPTDGNAGLLAEPQIAMFCGKLNMHMNVQNGKWESDPSGTK 60

Query: 377  TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 556
            TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR RKQCKTHTHIVIPYRCLVG
Sbjct: 61   TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHTHIVIPYRCLVG 120

Query: 557  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 736
            EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
Sbjct: 121  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 180

Query: 737  GVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXX 916
            GVEFVCCPL                  VWWGGADTDYADG EDKVV              
Sbjct: 181  GVEFVCCPLAEESDSVDSADAEEDDSDVWWGGADTDYADGGEDKVVEVAEEEEVADVEEE 240

Query: 917  XXXXXXXXXXXXXXXXXXXXPYEEATERXXXXXXXXXXXXXXXXXXXXXXCSEQAETGPC 1096
                                PYEEATER                      CSEQAETGPC
Sbjct: 241  EADDDEDVEDGDEVEEEAEEPYEEATERTTSTATTTTTTTESVEEVVREVCSEQAETGPC 300

Query: 1097 RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSV---------------- 1228
            RAMISRWYFDVTEGKC PFFYGGCGGNRNNFDTEEYCMAVCGSV                
Sbjct: 301  RAMISRWYFDVTEGKCVPFFYGGCGGNRNNFDTEEYCMAVCGSVSTQSLLKTTSEPLPQD 360

Query: 1229 ---IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA 1399
               +PTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA
Sbjct: 361  PDKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA 420

Query: 1400 KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL 1579
            KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL
Sbjct: 421  KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL 480

Query: 1580 QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER 1759
            QAVPPRP HVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER
Sbjct: 481  QAVPPRPHHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER 540

Query: 1760 MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET 1939
            MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET
Sbjct: 541  MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET 600

Query: 1940 KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTN 2119
            KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTN
Sbjct: 601  KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTN 660

Query: 2120 IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXX 2299
            IKTEEISEVKMDAEF HDSG+EV HQKLVFFAEDVGSNKGAIIGL               
Sbjct: 661  IKTEEISEVKMDAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITL 720

Query: 2300 XXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
               KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 721  VMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 770


>ref|NP_001185754.1| amyloid beta A4 protein isoform 5 precursor [Mus musculus].
          Length = 733

 Score = 1256 bits (3251), Expect = 0.0
 Identities = 629/751 (83%), Positives = 632/751 (84%)
 Frame = +2

Query: 197  MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 376
            MLP LAL+LLAAWT RALEVPTDGNAGLLAEPQ+AMFCGKLNMHMNVQNGKWESDPSGTK
Sbjct: 1    MLPSLALLLLAAWTVRALEVPTDGNAGLLAEPQIAMFCGKLNMHMNVQNGKWESDPSGTK 60

Query: 377  TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 556
            TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR RKQCKTHTHIVIPYRCLVG
Sbjct: 61   TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHTHIVIPYRCLVG 120

Query: 557  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 736
            EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
Sbjct: 121  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 180

Query: 737  GVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXX 916
            GVEFVCCPL                  VWWGGADTDYADG EDKVV              
Sbjct: 181  GVEFVCCPLAEESDSVDSADAEEDDSDVWWGGADTDYADGGEDKVVEVAEEEEVADVEEE 240

Query: 917  XXXXXXXXXXXXXXXXXXXXPYEEATERXXXXXXXXXXXXXXXXXXXXXXCSEQAETGPC 1096
                                PYEEATER                      CSEQAETGPC
Sbjct: 241  EADDDEDVEDGDEVEEEAEEPYEEATERTTSTATTTTTTTESVEEVVREVCSEQAETGPC 300

Query: 1097 RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAASTPDAVDKYL 1276
            RAMISRWYFDVTEGKC PFFYGGCGGNRNNFDTEEYCMAVCGSV PTTAASTPDAVDKYL
Sbjct: 301  RAMISRWYFDVTEGKCVPFFYGGCGGNRNNFDTEEYCMAVCGSVFPTTAASTPDAVDKYL 360

Query: 1277 ETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKV 1456
            ETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKV
Sbjct: 361  ETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKV 420

Query: 1457 ESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVR 1636
            ESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRP HVFNMLKKYVR
Sbjct: 421  ESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPHHVFNMLKKYVR 480

Query: 1637 AEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQ 1816
            AEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQ
Sbjct: 481  AEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQ 540

Query: 1817 DEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQ 1996
            DEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQ
Sbjct: 541  DEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQ 600

Query: 1997 PWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDS 2176
            PWHPFGVDSVPANTENE                  GSGLTNIKTEEISEVKMDAEF HDS
Sbjct: 601  PWHPFGVDSVPANTENE------------------GSGLTNIKTEEISEVKMDAEFGHDS 642

Query: 2177 GYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXXKKKQYTSIHHGVVEVD 2356
            G+EV HQKLVFFAEDVGSNKGAIIGL                  KKKQYTSIHHGVVEVD
Sbjct: 643  GFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVD 702

Query: 2357 AAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
            AAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 703  AAVTPEERHLSKMQQNGYENPTYKFFEQMQN 733


>ref|NP_001185755.1| amyloid beta A4 protein isoform 6 precursor [Mus musculus].
          Length = 752

 Score = 1246 bits (3223), Expect = 0.0
 Identities = 629/770 (81%), Positives = 633/770 (82%), Gaps = 19/770 (2%)
 Frame = +2

Query: 197  MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 376
            MLP LAL+LLAAWT RALEVPTDGNAGLLAEPQ+AMFCGKLNMHMNVQNGKWESDPSGTK
Sbjct: 1    MLPSLALLLLAAWTVRALEVPTDGNAGLLAEPQIAMFCGKLNMHMNVQNGKWESDPSGTK 60

Query: 377  TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 556
            TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR RKQCKTHTHIVIPYRCLVG
Sbjct: 61   TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHTHIVIPYRCLVG 120

Query: 557  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 736
            EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
Sbjct: 121  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 180

Query: 737  GVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXX 916
            GVEFVCCPL                  VWWGGADTDYADG EDKVV              
Sbjct: 181  GVEFVCCPLAEESDSVDSADAEEDDSDVWWGGADTDYADGGEDKVVEVAEEEEVADVEEE 240

Query: 917  XXXXXXXXXXXXXXXXXXXXPYEEATERXXXXXXXXXXXXXXXXXXXXXXCSEQAETGPC 1096
                                PYEEATER                      CSEQAETGPC
Sbjct: 241  EADDDEDVEDGDEVEEEAEEPYEEATERTTSTATTTTTTTESVEEVVREVCSEQAETGPC 300

Query: 1097 RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSV---------------- 1228
            RAMISRWYFDVTEGKC PFFYGGCGGNRNNFDTEEYCMAVCGSV                
Sbjct: 301  RAMISRWYFDVTEGKCVPFFYGGCGGNRNNFDTEEYCMAVCGSVSTQSLLKTTSEPLPQD 360

Query: 1229 ---IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA 1399
               +PTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA
Sbjct: 361  PDKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA 420

Query: 1400 KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL 1579
            KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL
Sbjct: 421  KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL 480

Query: 1580 QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER 1759
            QAVPPRP HVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER
Sbjct: 481  QAVPPRPHHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER 540

Query: 1760 MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET 1939
            MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET
Sbjct: 541  MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET 600

Query: 1940 KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTN 2119
            KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENE                  GSGLTN
Sbjct: 601  KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENE------------------GSGLTN 642

Query: 2120 IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXX 2299
            IKTEEISEVKMDAEF HDSG+EV HQKLVFFAEDVGSNKGAIIGL               
Sbjct: 643  IKTEEISEVKMDAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITL 702

Query: 2300 XXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
               KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 703  VMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 752


>ref|NP_031497.2| amyloid beta A4 protein isoform 2 precursor [Mus musculus].
          Length = 695

 Score =  762 bits (1967), Expect = 0.0
 Identities = 384/407 (94%), Positives = 386/407 (94%)
 Frame = +2

Query: 1229 IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 1408
            +PTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL
Sbjct: 289  VPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 348

Query: 1409 PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 1588
            PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
Sbjct: 349  PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 408

Query: 1589 PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 1768
            PPRP HVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ
Sbjct: 409  PPRPHHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 468

Query: 1769 SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 1948
            SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT
Sbjct: 469  SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 528

Query: 1949 VELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT 2128
            VELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
Sbjct: 529  VELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT 588

Query: 2129 EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXX 2308
            EEISEVKMDAEF HDSG+EV HQKLVFFAEDVGSNKGAIIGL                  
Sbjct: 589  EEISEVKMDAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVML 648

Query: 2309 KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
            KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 649  KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 695



 Score =  436 bits (1120), Expect = e-122
 Identities = 210/268 (78%), Positives = 212/268 (79%)
 Frame = +2

Query: 197  MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 376
            MLP LAL+LLAAWT RALEVPTDGNAGLLAEPQ+AMFCGKLNMHMNVQNGKWESDPSGTK
Sbjct: 1    MLPSLALLLLAAWTVRALEVPTDGNAGLLAEPQIAMFCGKLNMHMNVQNGKWESDPSGTK 60

Query: 377  TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 556
            TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR RKQCKTHTHIVIPYRCLVG
Sbjct: 61   TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHTHIVIPYRCLVG 120

Query: 557  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 736
            EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
Sbjct: 121  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 180

Query: 737  GVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXX 916
            GVEFVCCPL                  VWWGGADTDYADG EDKVV              
Sbjct: 181  GVEFVCCPLAEESDSVDSADAEEDDSDVWWGGADTDYADGGEDKVVEVAEEEEVADVEEE 240

Query: 917  XXXXXXXXXXXXXXXXXXXXPYEEATER 1000
                                PYEEATER
Sbjct: 241  EADDDEDVEDGDEVEEEAEEPYEEATER 268


>ref|NP_001095925.1| amyloid-like protein 2 isoform a [Mus musculus].
          Length = 751

 Score =  442 bits (1138), Expect = e-124
 Identities = 235/465 (50%), Positives = 305/465 (65%), Gaps = 5/465 (1%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAA 1246
            CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC ++IP T  
Sbjct: 310  CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPTPL 369

Query: 1247 STPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKK 1426
             T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNLPK +++
Sbjct: 370  PTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKTERQ 428

Query: 1427 AVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRH 1606
             +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ PPRP  
Sbjct: 429  TLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRIALENYLAALQSDPPRPHR 488

Query: 1607 VFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLY 1786
            +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI ER NQSLSLLY
Sbjct: 489  ILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLY 548

Query: 1787 NVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPV 1966
             VP VA+EIQ+E+DELLQ+++       A+M          D    S++E    V +   
Sbjct: 549  KVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTSSISENPVDVRVSSE 591

Query: 1967 NGEFSLDDLQPWHPFGVDSVPANTENE----VEPVDARPAADRGLTTRPGSGLTNIKTEE 2134
              E  +    P HPF     P+ +ENE     E       A+  +         N+  +E
Sbjct: 592  ESE-EIPPFHPLHPF-----PSLSENEGSGMAEQDGGLIGAEEKVINSKNKMDENMVIDE 645

Query: 2135 ISEVK-MDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXXXXXK 2311
              +VK M        G E   + +    ED   +  A+IGL                  +
Sbjct: 646  TLDVKEMIFNAERVGGLEEEPESVGPLREDFSLSSNALIGLLVIAVAIATVIVISLVMLR 705

Query: 2312 KKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 2446
            K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 706  KRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 750



 Score =  267 bits (683), Expect = 3e-71
 Identities = 123/202 (60%), Positives = 154/202 (76%), Gaps = 3/202 (1%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEVPTDGNAGL---LAEPQVAMFCGKLNMHMN 334
           ++A  A  ++ +L  L L   AA  A  +E     NAG    +AEPQ+AMFCGKLNMH+N
Sbjct: 6   TAAAAATGKLLVLLLLGLTAPAAALAGYIEALA-ANAGTGFAVAEPQIAMFCGKLNMHVN 64

Query: 335 VQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCK 514
           +Q GKWE DP+GTK+C+GTKE +LQYCQE+YPELQITNV+EANQPV I +WC+R ++QCK
Sbjct: 65  IQTGKWEPDPTGTKSCLGTKEEVLQYCQEIYPELQITNVMEANQPVNIDSWCRRDKRQCK 124

Query: 515 THTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLH 694
             +HIVIP++CLVGEFVSD LLVPD C+F HQERM+VCE H  WHT+ KE C  +   L+
Sbjct: 125 --SHIVIPFKCLVGEFVSDVLLVPDNCQFFHQERMEVCEKHQRWHTLVKEACLTEGLTLY 182

Query: 695 DYGMLLPCGIDKFRGVEFVCCP 760
            YGMLLPCG+D+F G E+VCCP
Sbjct: 183 SYGMLLPCGVDQFHGTEYVCCP 204


>ref|NP_001095926.1| amyloid-like protein 2 isoform b [Mus musculus].
          Length = 707

 Score =  353 bits (906), Expect = 5e-97
 Identities = 203/425 (47%), Positives = 264/425 (62%), Gaps = 19/425 (4%)
 Frame = +2

Query: 1229 IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 1408
            +P T   T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNL
Sbjct: 308  VPPTPLPTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNL 366

Query: 1409 PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 1588
            PK +++ +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ 
Sbjct: 367  PKTERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRIALENYLAALQSD 426

Query: 1589 PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 1768
            PPRP  +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI ER NQ
Sbjct: 427  PPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQ 486

Query: 1769 SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 1948
            SLSLLY VP VA+EIQ+E+DELLQ+++       A+M          D    S++E    
Sbjct: 487  SLSLLYKVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTSSISENPVD 529

Query: 1949 VELLPVNGEFSLDDLQPWHPFGVDSVPANTENE-VEPVDARPAADRGLTTRPGSGLTNIK 2125
            V +     E  +    P HPF     P+ +ENE  +P    P            GL   +
Sbjct: 530  VRVSSEESE-EIPPFHPLHPF-----PSLSENEDTQPELYHPMKKGSGMAEQDGGLIGAE 583

Query: 2126 TEEI-SEVKMDAEFRHDSGYEVHHQKLVFFAEDVGS-----------------NKGAIIG 2251
             + I S+ KMD     D   +V  ++++F AE VG                  +  A+IG
Sbjct: 584  EKVINSKNKMDENMVIDETLDV--KEMIFNAERVGGLEEEPESVGPLREDFSLSSNALIG 641

Query: 2252 LXXXXXXXXXXXXXXXXXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKF 2431
            L                  +K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTYK+
Sbjct: 642  LLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKY 701

Query: 2432 FEQMQ 2446
             EQMQ
Sbjct: 702  LEQMQ 706



 Score =  267 bits (683), Expect = 3e-71
 Identities = 123/202 (60%), Positives = 154/202 (76%), Gaps = 3/202 (1%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEVPTDGNAGL---LAEPQVAMFCGKLNMHMN 334
           ++A  A  ++ +L  L L   AA  A  +E     NAG    +AEPQ+AMFCGKLNMH+N
Sbjct: 6   TAAAAATGKLLVLLLLGLTAPAAALAGYIEALA-ANAGTGFAVAEPQIAMFCGKLNMHVN 64

Query: 335 VQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCK 514
           +Q GKWE DP+GTK+C+GTKE +LQYCQE+YPELQITNV+EANQPV I +WC+R ++QCK
Sbjct: 65  IQTGKWEPDPTGTKSCLGTKEEVLQYCQEIYPELQITNVMEANQPVNIDSWCRRDKRQCK 124

Query: 515 THTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLH 694
             +HIVIP++CLVGEFVSD LLVPD C+F HQERM+VCE H  WHT+ KE C  +   L+
Sbjct: 125 --SHIVIPFKCLVGEFVSDVLLVPDNCQFFHQERMEVCEKHQRWHTLVKEACLTEGLTLY 182

Query: 695 DYGMLLPCGIDKFRGVEFVCCP 760
            YGMLLPCG+D+F G E+VCCP
Sbjct: 183 SYGMLLPCGVDQFHGTEYVCCP 204


>ref|NP_033821.1| amyloid-like protein 2 isoform c [Mus musculus].
          Length = 695

 Score =  352 bits (902), Expect = 1e-96
 Identities = 198/411 (48%), Positives = 257/411 (62%), Gaps = 5/411 (1%)
 Frame = +2

Query: 1229 IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 1408
            +P T   T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNL
Sbjct: 308  VPPTPLPTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNL 366

Query: 1409 PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 1588
            PK +++ +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ 
Sbjct: 367  PKTERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRIALENYLAALQSD 426

Query: 1589 PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 1768
            PPRP  +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI ER NQ
Sbjct: 427  PPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQ 486

Query: 1769 SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 1948
            SLSLLY VP VA+EIQ+E+DELLQ+++       A+M          D    S++E    
Sbjct: 487  SLSLLYKVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTSSISENPVD 529

Query: 1949 VELLPVNGEFSLDDLQPWHPFGVDSVPANTENE----VEPVDARPAADRGLTTRPGSGLT 2116
            V +     E  +    P HPF     P+ +ENE     E       A+  +         
Sbjct: 530  VRVSSEESE-EIPPFHPLHPF-----PSLSENEGSGMAEQDGGLIGAEEKVINSKNKMDE 583

Query: 2117 NIKTEEISEVK-MDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXX 2293
            N+  +E  +VK M        G E   + +    ED   +  A+IGL             
Sbjct: 584  NMVIDETLDVKEMIFNAERVGGLEEEPESVGPLREDFSLSSNALIGLLVIAVAIATVIVI 643

Query: 2294 XXXXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 2446
                 +K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 644  SLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 694



 Score =  267 bits (683), Expect = 3e-71
 Identities = 123/202 (60%), Positives = 154/202 (76%), Gaps = 3/202 (1%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEVPTDGNAGL---LAEPQVAMFCGKLNMHMN 334
           ++A  A  ++ +L  L L   AA  A  +E     NAG    +AEPQ+AMFCGKLNMH+N
Sbjct: 6   TAAAAATGKLLVLLLLGLTAPAAALAGYIEALA-ANAGTGFAVAEPQIAMFCGKLNMHVN 64

Query: 335 VQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCK 514
           +Q GKWE DP+GTK+C+GTKE +LQYCQE+YPELQITNV+EANQPV I +WC+R ++QCK
Sbjct: 65  IQTGKWEPDPTGTKSCLGTKEEVLQYCQEIYPELQITNVMEANQPVNIDSWCRRDKRQCK 124

Query: 515 THTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLH 694
             +HIVIP++CLVGEFVSD LLVPD C+F HQERM+VCE H  WHT+ KE C  +   L+
Sbjct: 125 --SHIVIPFKCLVGEFVSDVLLVPDNCQFFHQERMEVCEKHQRWHTLVKEACLTEGLTLY 182

Query: 695 DYGMLLPCGIDKFRGVEFVCCP 760
            YGMLLPCG+D+F G E+VCCP
Sbjct: 183 SYGMLLPCGVDQFHGTEYVCCP 204


>ref|NP_031493.2| amyloid-like protein 1 [Mus musculus].
          Length = 654

 Score =  241 bits (616), Expect = 2e-63
 Identities = 147/399 (36%), Positives = 216/399 (54%), Gaps = 4/399 (1%)
 Frame = +2

Query: 1256 DAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVI 1435
            D VD Y   PG+  EH  F +AK  LE +   ++++VMREW  A+ Q+KNLPKAD++A+ 
Sbjct: 296  DGVDVYFGMPGEIGEHEGFLRAKMDLEERRMRQINEVMREWAMADSQSKNLPKADRQALN 355

Query: 1436 QHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN 1615
            +HFQ  +++LE++ + ERQ+LVETH  RV A++ND+RR ALE ++ ALQ  PP+   V  
Sbjct: 356  EHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQGDPPQAERVLM 415

Query: 1616 MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVP 1795
             L++Y+RAEQK+++HTL+H++HV  VDP+KA Q+R QV THL+VI ERMNQSL LL   P
Sbjct: 416  ALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVQTHLQVIEERMNQSLGLLDQNP 475

Query: 1796 AVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGE 1975
             +A+E++ ++ ELL  E                       L PS  +       +P +  
Sbjct: 476  HLAQELRPQIQELLLAEH----------------------LGPSELDAS-----VPGSSS 508

Query: 1976 FSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMD 2155
                 LQP             E++ +P    P   +G T +  S     K   + + +  
Sbjct: 509  EDKGSLQP------------PESKDDPPVTLP---KGSTDQESSSSGREKLTPLEQYEQK 553

Query: 2156 AEFRHDSGYEVHH---QKLVFFAEDVGSNKGAIIG-LXXXXXXXXXXXXXXXXXXKKKQY 2323
                   G+  H    Q+        G ++ A+ G L                  KKK Y
Sbjct: 554  VNASAPRGFPFHSSDIQRDELAPSGTGVSREALSGLLIMGAGGGSLIVLSLLLLRKKKPY 613

Query: 2324 TSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQ 2440
             +I HGVVEVD  +T EE+ L ++Q++GYENPTY+F E+
Sbjct: 614  GTISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEE 652



 Score =  183 bits (464), Expect = 8e-46
 Identities = 89/195 (45%), Positives = 125/195 (64%), Gaps = 2/195 (1%)
 Frame = +2

Query: 182 PRRVAMLPGLALVLLAAWTARA-LEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWES 358
           P  + +L  L+L+LL A  A   L V +   A      QVA  CG+L +H +++ G+WE 
Sbjct: 17  PPPLPLLLPLSLLLLRAQLAVGNLAVGSPSAAEAPGSAQVAGLCGRLTLHRDLRTGRWEP 76

Query: 359 DPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRK-QCKTHTHIVI 535
           DP  ++ C+   + +L+YC+++YPEL I  V +A Q + ++ WC  +R  +C    H V+
Sbjct: 77  DPQRSRRCLLDPQRVLEYCRQMYPELHIARVEQAAQAIPMERWCGGTRSGRCAHPHHEVV 136

Query: 536 PYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLP 715
           P+ CL GEFVS+ALLVP+ C+FLHQERMD CE+    H  A+E CS +   LH  GMLLP
Sbjct: 137 PFHCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLP 196

Query: 716 CGIDKFRGVEFVCCP 760
           CG D+FRGVE+VCCP
Sbjct: 197 CGSDRFRGVEYVCCP 211


>ref|NP_035594.1| kunitz-type protease inhibitor 2 isoform a [Mus musculus].
          Length = 252

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 26/58 (44%), Positives = 35/58 (60%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTT 1240
            C      G CRA I RW++++T+G C PF YGGC GN NN+ ++E C+  C  V   T
Sbjct: 38   CGVSKVVGKCRASIPRWWYNITDGSCQPFVYGGCEGNGNNYQSKEECLDKCAGVTENT 95



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 25/51 (49%), Positives = 33/51 (64%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 1219
            C  +A TGPCRA   RWY+D  +  C  F YGGC GN+N++ ++E CM  C
Sbjct: 133  CVPKAVTGPCRAAFPRWYYDTEKNSCISFIYGGCRGNKNSYLSQEACMQHC 183


  Database: RefSeq49_MP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 15,617,559
  Number of sequences in database:  30,036
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 30036
Number of Hits to DB: 100,032,402
Number of extensions: 2625599
Number of successful extensions: 10224
Number of sequences better than 1.0e-05: 31
Number of HSP's gapped: 10109
Number of HSP's successfully gapped: 43
Length of query: 1049
Length of database: 15,617,559
Length adjustment: 112
Effective length of query: 937
Effective length of database: 12,253,527
Effective search space: 11481554799
Effective search space used: 11481554799
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)

BLASTX 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BFLT1_0085_G08
         (3148 letters)

Database: RefSeq49_SP.fasta 
           24,897 sequences; 11,343,932 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Alignment   gi|NP_999537.1| amyloid beta A4 protein [Sus scrofa].               1312   0.0  
Alignment   gi|XP_003358940.1| PREDICTED: amyloid beta A4 protein-like [Sus...   640   0.0  
Alignment   gi|XP_003357409.1| PREDICTED: amyloid-like protein 2, partial [...   395   e-110
Alignment   gi|XP_003127129.1| PREDICTED: amyloid-like protein 1-like [Sus ...   142   1e-33
Alignment   gi|XP_003359739.1| PREDICTED: collagen alpha-3(VI) chain [Sus s...    69   2e-11
Alignment   gi|XP_001928130.2| PREDICTED: collagen alpha-3(VI) chain isofor...    69   2e-11
Alignment   gi|XP_001928122.2| PREDICTED: collagen alpha-3(VI) chain isofor...    69   2e-11
Alignment   gi|XP_003127156.1| PREDICTED: kunitz-type protease inhibitor 2-...    67   8e-11
Alignment   gi|NP_001157478.1| protein AMBP precursor [Sus scrofa].               61   4e-09
Alignment   gi|NP_001128730.1| hypothetical protein LOC100155068 [Sus scrof...    61   4e-09

>ref|NP_999537.1| amyloid beta A4 protein [Sus scrofa].
          Length = 770

 Score = 1312 bits (3395), Expect = 0.0
 Identities = 658/770 (85%), Positives = 659/770 (85%), Gaps = 19/770 (2%)
 Frame = +2

Query: 197  MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 376
            MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK
Sbjct: 1    MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTK 60

Query: 377  TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 556
            TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG
Sbjct: 61   TCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVG 120

Query: 557  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 736
            EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
Sbjct: 121  EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR 180

Query: 737  GVEFVCCPLXXXXXXXXXXXXXXXXXXVWWGGADTDYADGSEDKVVXXXXXXXXXXXXXX 916
            GVEFVCCPL                  VWWGGADTDYADGSEDKVV              
Sbjct: 181  GVEFVCCPLAEESDNIDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVADVEEE 240

Query: 917  XXXXXXXXXXXXXXXXXXXXPYEEATERXXXXXXXXXXXXXXXXXXXXXXCSEQAETGPC 1096
                                PYEEATER                      CSEQAETGPC
Sbjct: 241  EAEDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPC 300

Query: 1097 RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSV---------------- 1228
            RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSV                
Sbjct: 301  RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVMSQSLLKTTQEHLPQD 360

Query: 1229 ---IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA 1399
               +PTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA
Sbjct: 361  PVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA 420

Query: 1400 KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL 1579
            KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL
Sbjct: 421  KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL 480

Query: 1580 QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER 1759
            QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER
Sbjct: 481  QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER 540

Query: 1760 MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET 1939
            MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET
Sbjct: 541  MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET 600

Query: 1940 KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTN 2119
            KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTN
Sbjct: 601  KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTN 660

Query: 2120 IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXXX 2299
            IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGL               
Sbjct: 661  IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITL 720

Query: 2300 XXXKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 2449
               KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Sbjct: 721  VMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 770


>ref|XP_003358940.1| PREDICTED: amyloid beta A4 protein-like [Sus scrofa].
          Length = 422

 Score =  640 bits (1651), Expect = 0.0
 Identities = 323/347 (93%), Positives = 324/347 (93%), Gaps = 19/347 (5%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSV------ 1228
            CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSV      
Sbjct: 6    CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVMSQSLL 65

Query: 1229 -------------IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVM 1369
                         +PTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVM
Sbjct: 66   KTTQEHLPQDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVM 125

Query: 1370 REWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRR 1549
            REWEEAERQAKNLPKADKKAVIQ    KVESLEQEAANERQQLVETHMARVEAMLNDRRR
Sbjct: 126  REWEEAERQAKNLPKADKKAVIQ----KVESLEQEAANERQQLVETHMARVEAMLNDRRR 181

Query: 1550 LALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQV 1729
            LALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQV
Sbjct: 182  LALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQV 241

Query: 1730 MTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGN 1909
            MTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGN
Sbjct: 242  MTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGN 301

Query: 1910 DALMPSLTETKTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEV 2050
            DALMPSLTETKTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEV
Sbjct: 302  DALMPSLTETKTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEV 348


>ref|XP_003357409.1| PREDICTED: amyloid-like protein 2, partial [Sus scrofa].
          Length = 744

 Score =  395 bits (1016), Expect = e-110
 Identities = 216/439 (49%), Positives = 285/439 (64%), Gaps = 10/439 (2%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTTAA 1246
            CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC ++IP T  
Sbjct: 317  CSQEALTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPTPL 376

Query: 1247 STPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKK 1426
             T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNLPKA+++
Sbjct: 377  PTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQ 435

Query: 1427 AVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRH 1606
             +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQA PPRP  
Sbjct: 436  TLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRVALENYLAALQADPPRPHR 495

Query: 1607 VFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLY 1786
            +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI ER NQSLSLLY
Sbjct: 496  ILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLY 555

Query: 1787 NVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEP---RISYGNDALMPSLTETKTTVEL 1957
             VP VA+EIQ+E+DELLQ+++   D   A++   P   R+S      MP L         
Sbjct: 556  KVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESDEMPPLYPLH-PFPS 614

Query: 1958 LPVNGEFSLDDLQP--WHPFGVDSVPANTEN-----EVEPVDARPAADRGLTTRPGSGLT 2116
            LP N     +D QP  +HP    S     +      E + ++++   D  +         
Sbjct: 615  LPEN-----EDPQPELYHPVKKGSALGEQDGGLIGAEEKVINSKKKVDENMVID------ 663

Query: 2117 NIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLXXXXXXXXXXXXXX 2296
              +T ++ E+  +AE     G E   +      ED G +  A+IGL              
Sbjct: 664  --ETLDVKEMIFNAE--RVGGLEEAPESTGPLREDFGLSSSALIGLLVIAVAIATVIVIS 719

Query: 2297 XXXXKKKQYTSIHHGVVEV 2353
                +K+QY +I HG+VEV
Sbjct: 720  LVMLRKRQYGTISHGIVEV 738



 Score =  268 bits (685), Expect = 1e-71
 Identities = 124/202 (61%), Positives = 153/202 (75%), Gaps = 3/202 (1%)
 Frame = +2

Query: 164 SSALGAPRRVAMLPGLALVLLAAWTARALEVPTDGNAGL---LAEPQVAMFCGKLNMHMN 334
           ++A  A  +  +L  L L   AA  A  +E     NAG    +AEPQ+AMFCGKLNMH+N
Sbjct: 6   TAAAAATGKFLLLLLLGLSAPAAALAGYIEALA-ANAGTGFAVAEPQIAMFCGKLNMHVN 64

Query: 335 VQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCK 514
           +Q GKWE DP+GTK+C GTKE +LQYCQE+YPELQITNV+EANQPV + NWC+R +KQCK
Sbjct: 65  IQTGKWEPDPTGTKSCFGTKEEVLQYCQEMYPELQITNVMEANQPVRVDNWCRRDKKQCK 124

Query: 515 THTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLH 694
             +H+VIP +CLVGEFVSD LLVP+KC+F H+ERM+VCE H HWHTV KE C  +   L+
Sbjct: 125 --SHVVIPSKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMTLY 182

Query: 695 DYGMLLPCGIDKFRGVEFVCCP 760
            YGMLLPCG+D+F G E+VCCP
Sbjct: 183 SYGMLLPCGVDQFHGTEYVCCP 204


>ref|XP_003127129.1| PREDICTED: amyloid-like protein 1-like [Sus scrofa].
          Length = 181

 Score =  142 bits (357), Expect = 1e-33
 Identities = 66/127 (51%), Positives = 86/127 (67%), Gaps = 1/127 (0%)
 Frame = +2

Query: 383 IGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRK-QCKTHTHIVIPYRCLVGE 559
           +G+  G      E+YPELQI  V +A Q + ++ WC  +R  +C    H V+P+RCL GE
Sbjct: 31  VGSLAGGSPSAAEMYPELQIARVEQATQAIPMEQWCGDARGGRCAHPHHQVVPFRCLPGE 90

Query: 560 FVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRG 739
           FVS+ALLVP+ C+FLHQERMD CE+    H  A+E C+ +   LH  GMLLPCG D+FRG
Sbjct: 91  FVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACNSQGLILHGSGMLLPCGADRFRG 150

Query: 740 VEFVCCP 760
           VE+VCCP
Sbjct: 151 VEYVCCP 157


>ref|XP_003359739.1| PREDICTED: collagen alpha-3(VI) chain [Sus scrofa].
          Length = 2571

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 27/55 (49%), Positives = 33/55 (60%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVI 1231
            C    + G CR  I +WY D   G CA F+YGGCGGN N FD++E C  VC  V+
Sbjct: 2506 CKLPKDGGTCRKFIIKWYHDAVTGNCARFWYGGCGGNENRFDSQEECEKVCSPVL 2560


>ref|XP_001928130.2| PREDICTED: collagen alpha-3(VI) chain isoform 2 [Sus scrofa].
          Length = 2972

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 27/55 (49%), Positives = 33/55 (60%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVI 1231
            C    + G CR  I +WY D   G CA F+YGGCGGN N FD++E C  VC  V+
Sbjct: 2907 CKLPKDGGTCRKFIIKWYHDAVTGNCARFWYGGCGGNENRFDSQEECEKVCSPVL 2961


>ref|XP_001928122.2| PREDICTED: collagen alpha-3(VI) chain isoform 1 [Sus scrofa].
          Length = 3178

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 27/55 (49%), Positives = 33/55 (60%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVI 1231
            C    + G CR  I +WY D   G CA F+YGGCGGN N FD++E C  VC  V+
Sbjct: 3113 CKLPKDGGTCRKFIIKWYHDAVTGNCARFWYGGCGGNENRFDSQEECEKVCSPVL 3167


>ref|XP_003127156.1| PREDICTED: kunitz-type protease inhibitor 2-like isoform 1 [Sus
            scrofa].
          Length = 252

 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 28/58 (48%), Positives = 35/58 (60%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVIPTT 1240
            C      G CRA I RW+++VT G C  F YGGC GN NN+ T+E C+A C  V  +T
Sbjct: 38   CQVPKVVGRCRASIPRWWYNVTGGSCQQFVYGGCEGNDNNYMTKEECLAKCAGVTEST 95



 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 25/51 (49%), Positives = 34/51 (66%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 1219
            C+ +A TGPCRA   RWYF+  +  C  F YGGC GN+N++ ++E CM  C
Sbjct: 133  CTAKAVTGPCRAAFPRWYFNAEKNSCDKFIYGGCRGNKNSYHSKEECMQRC 183


>ref|NP_001157478.1| protein AMBP precursor [Sus scrofa].
          Length = 352

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 25/52 (48%), Positives = 29/52 (55%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCG 1222
            CS    +GPCR     W FD  +GKC  F YGGC GN N F +E+ C   CG
Sbjct: 287  CSLPIVSGPCRGFFQLWAFDAVQGKCVLFNYGGCQGNGNQFYSEKECKEYCG 338



 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 22/54 (40%), Positives = 31/54 (57%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSV 1228
            C      GPC  MI R++++ +   C  F YGGC GN NNF +E+ C+  C +V
Sbjct: 231  CQLGYSQGPCLGMIKRYFYNGSSMACETFHYGGCMGNGNNFVSEKECLQTCRTV 284


>ref|NP_001128730.1| hypothetical protein LOC100155068 [Sus scrofa].
          Length = 303

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 22/51 (43%), Positives = 35/51 (68%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 1219
            C+ +A+ GPC+AM+ R++F++   +C  F YGGC GN+N F++ E C   C
Sbjct: 50   CAMKADDGPCKAMMKRFFFNINTQQCEEFIYGGCEGNQNRFESLEECKEKC 100



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 23/51 (45%), Positives = 32/51 (62%)
 Frame = +2

Query: 1067 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 1219
            C   A+ G C+A   R+Y++   GKC PF Y GCGGN NNF +++ C+  C
Sbjct: 216  CLTPADRGLCQANERRFYYNSVIGKCRPFKYSGCGGNENNFTSKKACLKTC 266


  Database: RefSeq49_SP.fasta
    Posted date:  Oct 17, 2011  1:42 PM
  Number of letters in database: 11,343,932
  Number of sequences in database:  24,897
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 24897
Number of Hits to DB: 75,085,779
Number of extensions: 2200284
Number of successful extensions: 7608
Number of sequences better than 1.0e-05: 20
Number of HSP's gapped: 7545
Number of HSP's successfully gapped: 24
Length of query: 1049
Length of database: 11,343,932
Length adjustment: 109
Effective length of query: 940
Effective length of database: 8,630,159
Effective search space: 8112349460
Effective search space used: 8112349460
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)

BLASTN 2.2.24 [Aug-08-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BFLT1_0085_G08
         (3148 letters)

Database: Sscrofa_10.2.fasta 
           4582 sequences; 2,808,509,378 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Sscrofa_Chr13                                                        1552   0.0  
gb|GL895340.2| Sus scrofa unplaced genomic scaffold ChrUScaf3224      170   3e-39
Sscrofa_Chr09                                                          74   5e-10

>Sscrofa_Chr13 
||          Length = 218635234

 Score = 1552 bits (783), Expect = 0.0
 Identities = 783/783 (100%)
 Strand = Plus / Minus

                                                                             
Query: 2349      aggttgacgcagctgtgaccccggaggagcgccacctctccaagatgcagcagaatggct 2408
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199291816 aggttgacgcagctgtgaccccggaggagcgccacctctccaagatgcagcagaatggct 199291757

                                                                             
Query: 2409      atgaaaacccaacttacaagttctttgagcagatgcagaactagaccgccgccacagcag 2468
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199291756 atgaaaacccaacttacaagttctttgagcagatgcagaactagaccgccgccacagcag 199291697

                                                                             
Query: 2469      cctctgaagttggacagcaaaaccattgcttcactacccattggtgttcatttatagaat 2528
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199291696 cctctgaagttggacagcaaaaccattgcttcactacccattggtgttcatttatagaat 199291637

                                                                             
Query: 2529      aatggggaaagacacaaacccttctgttttattatttactcatgatcgcctttcagcagc 2588
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199291636 aatggggaaagacacaaacccttctgttttattatttactcatgatcgcctttcagcagc 199291577

                                                                             
Query: 2589      tgtgctgtaacacaagtagatgcctgaacttgaattaatattacgaatcagtaatgtatt 2648
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199291576 tgtgctgtaacacaagtagatgcctgaacttgaattaatattacgaatcagtaatgtatt 199291517

                                                                             
Query: 2649      ctctctctttacatttccggtctctacactacattattaatgggttttgtgtactgtaaa 2708
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199291516 ctctctctttacatttccggtctctacactacattattaatgggttttgtgtactgtaaa 199291457

                                                                             
Query: 2709      gaatgaagctgtatcaaactagtgcatgaatagattccctcctgattatttatcatgtag 2768
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199291456 gaatgaagctgtatcaaactagtgcatgaatagattccctcctgattatttatcatgtag 199291397

                                                                             
Query: 2769      ccccttagccagttgtatattattcttgtggttttgtgatccaattaagtcctactttga 2828
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199291396 ccccttagccagttgtatattattcttgtggttttgtgatccaattaagtcctactttga 199291337

                                                                             
Query: 2829      aatatgctttaagaatcgatgggggatgcttcatgtgaacgtgggagtttagctgcttct 2888
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199291336 aatatgctttaagaatcgatgggggatgcttcatgtgaacgtgggagtttagctgcttct 199291277

                                                                             
Query: 2889      cttgcctaagtattcttttcctgatcactatgcattttaaaggtaaacatttttatgtat 2948
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199291276 cttgcctaagtattcttttcctgatcactatgcattttaaaggtaaacatttttatgtat 199291217

                                                                             
Query: 2949      tccaaatgagttagagaagttttttccacgattgcatttgactgtacagattgctgcttc 3008
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199291216 tccaaatgagttagagaagttttttccacgattgcatttgactgtacagattgctgcttc 199291157

                                                                             
Query: 3009      tgctatatttgtgatataggaattatgaggatacacgtttatttctttgtgcctgtttta 3068
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199291156 tgctatatttgtgatataggaattatgaggatacacgtttatttctttgtgcctgtttta 199291097

                                                                             
Query: 3069      tgtgcacacattaggcattgagaattaaaacttcttttgtccgtgtaccttcggatcttt 3128
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199291096 tgtgcacacattaggcattgagaattaaaacttcttttgtccgtgtaccttcggatcttt 199291037

                    
Query: 3129      gat 3131
                 |||
Sbjct: 199291036 gat 199291034



 Score =  466 bits (235), Expect = e-128
 Identities = 235/235 (100%)
 Strand = Plus / Minus

                                                                             
Query: 22        cgagccccgccgccgcgctgctgttcggtcagtttcctcggcagcggtaggagagagcac 81
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199568764 cgagccccgccgccgcgctgctgttcggtcagtttcctcggcagcggtaggagagagcac 199568705

                                                                             
Query: 82        ccggggcagcgcgagcgcggggccaccgtagacagcggcagcgacaccggcagagcaagg 141
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199568704 ccggggcagcgcgagcgcggggccaccgtagacagcggcagcgacaccggcagagcaagg 199568645

                                                                             
Query: 142       gcgcggcggatcccacgcgaacagcagcgcactcggtgccccgcgcagggtcgcgatgct 201
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199568644 gcgcggcggatcccacgcgaacagcagcgcactcggtgccccgcgcagggtcgcgatgct 199568585

                                                                        
Query: 202       gcccggtttggcactggtcctgctggccgcctggacggctcgggcgctggaggtg 256
                 |||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199568584 gcccggtttggcactggtcctgctggccgcctggacggctcgggcgctggaggtg 199568530



 Score =  442 bits (223), Expect = e-121
 Identities = 223/223 (100%)
 Strand = Plus / Minus

                                                                             
Query: 1826      gatgagctgctgcagaaagagcaaaactactcggatgatgtcttggccaacatgatcagc 1885
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199323023 gatgagctgctgcagaaagagcaaaactactcggatgatgtcttggccaacatgatcagc 199322964

                                                                             
Query: 1886      gaaccgaggatcagttatggaaacgatgctctcatgccgtctctgactgaaaccaaaacc 1945
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199322963 gaaccgaggatcagttatggaaacgatgctctcatgccgtctctgactgaaaccaaaacc 199322904

                                                                             
Query: 1946      accgtggagcttcttcctgtgaatggagagttcagcctggatgatctccagccctggcat 2005
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199322903 accgtggagcttcttcctgtgaatggagagttcagcctggatgatctccagccctggcat 199322844

                                                            
Query: 2006      ccttttggggtagactctgtgcctgccaacacagaaaatgaag 2048
                 |||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199322843 ccttttggggtagactctgtgcctgccaacacagaaaatgaag 199322801



 Score =  389 bits (196), Expect = e-105
 Identities = 196/196 (100%)
 Strand = Plus / Minus

                                                                             
Query: 663       agacctgtagtgagaagagtacgaacttgcatgactatggcatgttgctgccctgtggaa 722
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199474141 agacctgtagtgagaagagtacgaacttgcatgactatggcatgttgctgccctgtggaa 199474082

                                                                             
Query: 723       ttgacaagttccgaggggtggagtttgtgtgttgcccactggccgaggaaagtgacaata 782
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199474081 ttgacaagttccgaggggtggagtttgtgtgttgcccactggccgaggaaagtgacaata 199474022

                                                                             
Query: 783       tcgactcagcagatgcagaagaggatgactcggacgtctggtggggtggagcagatacag 842
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199474021 tcgactcagcagatgcagaagaggatgactcggacgtctggtggggtggagcagatacag 199473962

                                 
Query: 843       actatgcagatggcag 858
                 ||||||||||||||||
Sbjct: 199473961 actatgcagatggcag 199473946



 Score =  341 bits (172), Expect = 1e-90
 Identities = 172/172 (100%)
 Strand = Plus / Minus

                                                                             
Query: 252       aggtgcccactgatggcaatgccggcctgcttgcagaaccccaggttgccatgttctgtg 311
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199507331 aggtgcccactgatggcaatgccggcctgcttgcagaaccccaggttgccatgttctgtg 199507272

                                                                             
Query: 312       gcaaactcaacatgcacatgaatgtgcagaatgggaagtgggagtcagatccgtcgggga 371
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199507271 gcaaactcaacatgcacatgaatgtgcagaatgggaagtgggagtcagatccgtcgggga 199507212

                                                                     
Query: 372       ccaaaacctgcattggcaccaaggaaggcatcttgcagtactgccaagaagt 423
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199507211 ccaaaacctgcattggcaccaaggaaggcatcttgcagtactgccaagaagt 199507160



 Score =  337 bits (170), Expect = 2e-89
 Identities = 170/170 (100%)
 Strand = Plus / Minus

                                                                             
Query: 1060      agaggtgtgctctgaacaagccgagacggggccgtgccgagcaatgatctcccgctggta 1119
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199420005 agaggtgtgctctgaacaagccgagacggggccgtgccgagcaatgatctcccgctggta 199419946

                                                                             
Query: 1120      ctttgatgtgactgaagggaagtgcgccccgttcttttacggcggatgtggcggcaaccg 1179
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199419945 ctttgatgtgactgaagggaagtgcgccccgttcttttacggcggatgtggcggcaaccg 199419886

                                                                   
Query: 1180      aaacaactttgacacagaggaatactgcatggccgtgtgtggcagcgtca 1229
                 ||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199419885 aaacaactttgacacagaggaatactgcatggccgtgtgtggcagcgtca 199419836



 Score =  325 bits (164), Expect = 8e-86
 Identities = 167/168 (99%)
 Strand = Plus / Minus

                                                                             
Query: 1430      gtgatccagcatttccaggagaaagtggagtctctggagcaggaagcagccaacgagagg 1489
                 ||||| ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199380167 gtgatgcagcatttccaggagaaagtggagtctctggagcaggaagcagccaacgagagg 199380108

                                                                             
Query: 1490      cagcagttggtggagacgcacatggccagagtggaggccatgcttaacgaccgccggcgc 1549
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199380107 cagcagttggtggagacgcacatggccagagtggaggccatgcttaacgaccgccggcgc 199380048

                                                                 
Query: 1550      ctggccctggagaattacatcacggctcttcaggctgttcctcctcgg 1597
                 ||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199380047 ctggccctggagaattacatcacggctcttcaggctgttcctcctcgg 199380000



 Score =  289 bits (146), Expect = 5e-75
 Identities = 149/150 (99%)
 Strand = Plus / Minus

                                                                             
Query: 2203      ggtgttcttcgcagaagatgtgggttcaaacaaaggtgccatcattggactcatggtggg 2262
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199302682 ggtgttcttcgcagaagatgtgggttcaaacaaaggtgccatcattggactcatggtggg 199302623

                                                                             
Query: 2263      tggtgttgtcatagcaaccgtgattgtcatcaccttagtgatgctgaagaagaaacagta 2322
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199302622 tggtgttgtcatagcaaccgtgattgtcatcaccttagtgatgctgaagaagaaacagta 199302563

                                               
Query: 2323      cacatctatccatcacggtgtggtggaggt 2352
                 |||||| |||||||||||||||||||||||
Sbjct: 199302562 cacatccatccatcacggtgtggtggaggt 199302533



 Score =  262 bits (132), Expect = 1e-66
 Identities = 135/136 (99%)
 Strand = Plus / Minus

                                                                             
Query: 1230      ttcctacaacagcagccagcaccccggatgccgttgacaagtatcttgagacacctggag 1289
                 ||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||
Sbjct: 199385121 ttcctacaacagcagccagcaccccagatgccgttgacaagtatcttgagacacctggag 199385062

                                                                             
Query: 1290      atgagaacgaacatgcgcatttccagaaagccaaagagaggctggaggccaagcaccgcg 1349
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199385061 atgagaacgaacatgcgcatttccagaaagccaaagagaggctggaggccaagcaccgcg 199385002

                                 
Query: 1350      agagaatgtcccaggt 1365
                 ||||||||||||||||
Sbjct: 199385001 agagaatgtcccaggt 199384986



 Score =  258 bits (130), Expect = 2e-65
 Identities = 130/130 (100%)
 Strand = Plus / Minus

                                                                             
Query: 422       gtctaccctgaactgcagatcaccaatgtggtagaagccaaccaaccagtgaccatccag 481
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199484787 gtctaccctgaactgcagatcaccaatgtggtagaagccaaccaaccagtgaccatccag 199484728

                                                                             
Query: 482       aactggtgcaagaggagccggaagcagtgcaagacccacactcacattgtgattccgtac 541
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199484727 aactggtgcaagaggagccggaagcagtgcaagacccacactcacattgtgattccgtac 199484668

                           
Query: 542       cgctgcttag 551
                 ||||||||||
Sbjct: 199484667 cgctgcttag 199484658



 Score =  254 bits (128), Expect = 3e-64
 Identities = 131/132 (99%)
 Strand = Plus / Minus

                                                                             
Query: 1597      gcctcgtcatgtgttcaacatgctcaagaagtatgtccgtgctgaacagaaagacagaca 1656
                 |||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Sbjct: 199362640 gcctcgtcatgtgttcaacatgctcaagaagtatgtccgtgccgaacagaaagacagaca 199362581

                                                                             
Query: 1657      gcacaccctaaagcattttgaacacgttcgcatggtagatccaaagaaagctgctcagat 1716
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199362580 gcacaccctaaagcattttgaacacgttcgcatggtagatccaaagaaagctgctcagat 199362521

                             
Query: 1717      ccgatcccaggt 1728
                 ||||||||||||
Sbjct: 199362520 ccgatcccaggt 199362509



 Score =  230 bits (116), Expect = 4e-57
 Identities = 116/116 (100%)
 Strand = Plus / Minus

                                                                             
Query: 549       tagttggcgagtttgtaagcgatgccctccttgttccggacaagtgcaagttcttacacc 608
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199476108 tagttggcgagtttgtaagcgatgccctccttgttccggacaagtgcaagttcttacacc 199476049

                                                                         
Query: 609       aggagaggatggatgtttgcgaaacccaccttcactggcacactgtggccaaagag 664
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199476048 aggagaggatggatgtttgcgaaacccaccttcactggcacactgtggccaaagag 199475993



 Score =  202 bits (102), Expect = 8e-49
 Identities = 105/106 (99%)
 Strand = Plus / Minus

                                                                             
Query: 2100      caggttccgggttgaccaacatcaagacggaagagatctctgaagtgaagatggatgcgg 2159
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199306512 caggttccgggttgaccaacatcaagacggaagagatctctgaagtgaagatggatgcgg 199306453

                                                               
Query: 2160      agttccgacacgattcgggctatgaggttcatcaccaaaaactggt 2205
                 |||||||||||||||| |||||||||||||||||||||||||||||
Sbjct: 199306452 agttccgacacgattcaggctatgaggttcatcaccaaaaactggt 199306407



 Score =  198 bits (100), Expect = 1e-47
 Identities = 106/108 (98%)
 Strand = Plus / Minus

                                                                             
Query: 1724      caggttatgacacacctccgtgtgatttacgagcgcatgaaccagtctctctccctgctc 1783
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199361680 caggttatgacacacctccgtgtgatttacgagcgcatgaaccagtctctctccctgctc 199361621

                                                                 
Query: 1784      tacaacgttcctgctgtggccgaggaaattcaggatgaagttgatgag 1831
                 |||||||||||||||||||| |||||||||||||||||||||| ||||
Sbjct: 199361620 tacaacgttcctgctgtggctgaggaaattcaggatgaagttggtgag 199361573



 Score =  155 bits (78), Expect = 2e-34
 Identities = 78/78 (100%)
 Strand = Plus / Minus

                                                                             
Query: 1361      caggtcatgagagagtgggaagaggcagaacgtcaagcaaagaacttgcctaaagctgat 1420
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199380932 caggtcatgagagagtgggaagaggcagaacgtcaagcaaagaacttgcctaaagctgat 199380873

                                   
Query: 1421      aagaaagcagtgatccag 1438
                 ||||||||||||||||||
Sbjct: 199380872 aagaaagcagtgatccag 199380855



 Score =  115 bits (58), Expect = 2e-22
 Identities = 58/58 (100%)
 Strand = Plus / Minus

                                                                           
Query: 2047      agtcgagcctgttgacgcccgccctgcagccgaccgaggactgaccactcgaccaggt 2104
                 ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 199313986 agtcgagcctgttgacgcccgccctgcagccgaccgaggactgaccactcgaccaggt 199313929


>gb|GL895340.2| Sus scrofa unplaced genomic scaffold ChrUScaf3224
          Length = 24765

 Score =  170 bits (86), Expect = 3e-39
 Identities = 86/86 (100%)
 Strand = Plus / Plus

                                                                         
Query: 1280  acacctggagatgagaacgaacatgcgcatttccagaaagccaaagagaggctggaggcc 1339
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 10648 acacctggagatgagaacgaacatgcgcatttccagaaagccaaagagaggctggaggcc 10707

                                       
Query: 1340  aagcaccgcgagagaatgtcccaggt 1365
             ||||||||||||||||||||||||||
Sbjct: 10708 aagcaccgcgagagaatgtcccaggt 10733



 Score = 67.9 bits (34), Expect = 3e-08
 Identities = 34/34 (100%)
 Strand = Plus / Plus

                                               
Query: 1230  ttcctacaacagcagccagcaccccggatgccgt 1263
             ||||||||||||||||||||||||||||||||||
Sbjct: 10514 ttcctacaacagcagccagcaccccggatgccgt 10547


>Sscrofa_Chr09 
||          Length = 153670197

 Score = 73.8 bits (37), Expect = 5e-10
 Identities = 85/101 (84%)
 Strand = Plus / Plus

                                                                            
Query: 1463     ctggagcaggaagcagccaacgagaggcagcagttggtggagacgcacatggccagagtg 1522
                |||||| |||||||||||| ||||| ||||||| ||||||| || ||| | ||  | |||
Sbjct: 63020480 ctggagaaggaagcagccagcgagaagcagcagctggtggaaacccacctcgcgcgggtg 63020539

                                                         
Query: 1523     gaggccatgcttaacgaccgccggcgcctggccctggagaa 1563
                ||||||||||| ||||||||||| ||  |||| ||||||||
Sbjct: 63020540 gaggccatgctcaacgaccgccgccgggtggcgctggagaa 63020580


  Database: Sscrofa_10.2.fasta
    Posted date:  Nov 16, 2011 10:34 AM
  Number of letters in database: 2,808,509,378
  Number of sequences in database:  4582
  
Lambda     K      H
    1.37    0.711     1.31 

Gapped
Lambda     K      H
    1.37    0.711     1.31 


Matrix: blastn matrix:1 -3
Gap Penalties: Existence: 5, Extension: 2
Number of Sequences: 4582
Number of Hits to DB: 83,791,340
Number of extensions: 480
Number of successful extensions: 480
Number of sequences better than 1.0e-05: 3
Number of HSP's gapped: 479
Number of HSP's successfully gapped: 19
Length of query: 3148
Length of database: 2,808,509,378
Length adjustment: 22
Effective length of query: 3126
Effective length of database: 2,808,408,574
Effective search space: 8779085202324
Effective search space used: 8779085202324
X1: 11 (21.8 bits)
X2: 15 (29.7 bits)
X3: 50 (99.1 bits)
S1: 18 (36.2 bits)
S2: 30 (60.0 bits)