BLASTX 2.2.24 [Aug-08-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MLTL1_0024_C11
(2001 letters)
Database: RefSeq49_BP.fasta
33,088 sequences; 17,681,374 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|XP_002685306.1| PREDICTED: titin [Bos taurus]. 1240 0.0
Alignment gi|XP_002703630.1| PREDICTED: titin [Bos taurus]. 1240 0.0
Alignment gi|NP_001179466.1| hemicentin-1 [Bos taurus]. 191 2e-48
Alignment gi|XP_002694295.1| PREDICTED: hemicentin 1 [Bos taurus]. 191 2e-48
Alignment gi|XP_002685157.1| PREDICTED: Down syndrome cell adhesion molec... 156 7e-38
Alignment gi|NP_001179817.2| roundabout homolog 1 [Bos taurus]. 155 1e-37
Alignment gi|XP_002684697.1| PREDICTED: roundabout, axon guidance recepto... 155 1e-37
Alignment gi|XP_614756.4| PREDICTED: roundabout 1 [Bos taurus]. 154 4e-37
Alignment gi|XP_002699249.1| PREDICTED: roundabout 1-like [Bos taurus]. 150 4e-36
Alignment gi|XP_002693048.1| PREDICTED: Down syndrome cell adhesion molec... 146 6e-35
>ref|XP_002685306.1| PREDICTED: titin [Bos taurus].
Length = 33452
Score = 1240 bits (3208), Expect = 0.0
Identities = 614/656 (93%), Positives = 629/656 (95%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PVKVTVGDSASLQCQL GTPEI VSW+KGDTKLRPTATYKMHFRNN+ATLVFNQVDSNDS
Sbjct: 7952 PVKVTVGDSASLQCQLGGTPEIAVSWFKGDTKLRPTATYKMHFRNNIATLVFNQVDSNDS 8011
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV
Sbjct: 8012 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 8071
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SWFKDGRP+KD PNIQ SFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE
Sbjct: 8072 SWFKDGRPVKDSPNIQASFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 8131
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
G+NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA
Sbjct: 8132 GKNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 8191
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
HLTILKVDKGD+GQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF+
Sbjct: 8192 HLTILKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFK 8251
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LEGRVAGSQPISVAWYKNN+EIHPT+NCEITFKNN LLLQ+K+A M DAGLYTCKVSNDA
Sbjct: 8252 LEGRVAGSQPISVAWYKNNIEIHPTSNCEITFKNNTLLLQIKRAGMDDAGLYTCKVSNDA 8311
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GSALCTSSIVIKEPKKPPVFDQHLTPVT SEGEF+QLSCHV GSEPIRIQWLKAGREIKP
Sbjct: 8312 GSALCTSSIVIKEPKKPPVFDQHLTPVTASEGEFVQLSCHVWGSEPIRIQWLKAGREIKP 8371
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
SDRCSFSFANGTAVLE KDVTKADAGDYVCKASNVAGSDTSKSKVT
Sbjct: 8372 SDRCSFSFANGTAVLELKDVTKADAGDYVCKASNVAGSDTSKSKVTIKDKPAAVPAAKKA 8431
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRI IHQKGD
Sbjct: 8432 AVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRILIHQKGD 8491
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLK 1802
EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV+ERKKQEKIEGDLRAMLKKTPVLK
Sbjct: 8492 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPVLK 8551
Query: 1803 KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEEETHRL 1970
KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFE+LKQ++ EETHRL
Sbjct: 8552 KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQTEGEETHRL 8607
Score = 506 bits (1304), Expect = e-143
Identities = 259/578 (44%), Positives = 359/578 (62%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++ +VGDS SLQCQ+AG+PEI VSWYKGDTKLRPT Y+ +F NNVATLVFN+V+ NDS
Sbjct: 6070 PLEASVGDSVSLQCQVAGSPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDS 6129
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+AENS+G SS T +QE++LPPSF+RQL+D+++TVGLPV C ++GS PI V
Sbjct: 6130 GEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQV 6189
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SW++DG L+D N+QTSF+DNVATL I QTD S +GQYSC+A+NP+G+ASSSARL E
Sbjct: 6190 SWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTARE 6249
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ PFFDI +D + GESADFECHVTG QP+++ W+KDN+EIR GGNY I+ + N+
Sbjct: 6250 PKKSPFFDIKPVSIDIIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTP 6309
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
HL ILKV KGD+GQYTC A N+VGKD C+AQL++KE PP F KKL + +G S
Sbjct: 6310 HLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE---PPKFVKKLEASKVAKQGESIH 6366
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE +++GS I V+W++N+ E+H + ++F ++ +L + +AS D+G Y C+ N
Sbjct: 6367 LECKISGSPEIKVSWFRNDSELHESWKYNMSFVDSVAVLTINEASAEDSGDYICEAHNGV 6426
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G A C++++ I K PPVF Q +P+ +G + C + G+ P + W+K ++++
Sbjct: 6427 GDASCSTALTI---KAPPVFTQKPSPIGALKGSDVVFQCEISGTPPFEVVWVKDRKQVRS 6483
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + N A L ++ AD G+Y CKA+N GSDT +
Sbjct: 6484 SKKFKITSKNFDASLHILNLEAADVGEYYCKATNEVGSDTCVCTLKFKEPPR-------- 6535
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
FV + + A V G +V W K K + + I +
Sbjct: 6536 -------FVKKLSDTSTLVGDAVELRAVVEGFQPISVVWLKDKGDVIRESENTRISFVDN 6588
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L++ +DSG Y C N G E + L V E
Sbjct: 6589 VATLQLGSPEASDSGKYVCQIKNDAGMRECSAILTVLE 6626
Score = 493 bits (1268), Expect = e-139
Identities = 252/577 (43%), Positives = 351/577 (60%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ +G+ +LQC++ GTPEI +SWYK TKLR YKM F+NNVA+LV N+VD +D G
Sbjct: 7012 VEAVIGEPITLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVG 7071
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY C+AEN VG V+SS+ L ++E+KLPPSF+R+L+DVQET+G PV FEC ++GSEP+ VS
Sbjct: 7072 EYTCKAENIVGAVASSSVLVIKERKLPPSFARKLKDVQETLGFPVAFECRINGSEPLQVS 7131
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+KDG LKD N+QTSF+ NVATL I QTD+S GQY+C+A+NP+G+ASSSA+L+L E
Sbjct: 7132 WYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLVLLEH 7191
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PPFFD+ VD +GES F+CHVTGT P+K+ WAKDNREIR GGNY+++ +EN+A
Sbjct: 7192 EVPPFFDLKPVSVDLALGESGSFKCHVTGTAPMKITWAKDNREIRPGGNYKMTLVENTAT 7251
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
LT+LK+ KGD GQYTCYA N GKDSC+A L ++E PP F KKL + + S R
Sbjct: 7252 LTVLKIGKGDAGQYTCYASNVAGKDSCSAHLGVQE---PPRFIKKLEPSRIVKQDESTRY 7308
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ GS I V WYK EI ++ ++F ++ +L++ S+ D+G YTC+ N AG
Sbjct: 7309 ECKIGGSPEIKVLWYKGETEIQESSKFRMSFVDSVAVLEMHGLSVEDSGDYTCEACNAAG 7368
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
SA T+S+ +KE PP+F + PV +G + L C ++G+ P ++ W K RE++
Sbjct: 7369 SASSTTSLKVKE---PPIFRKKPHPVETLKGADVHLECELQGTPPFQVSWHKDKRELRSG 7425
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ N + V AD G+Y CKA+N GSDT +T
Sbjct: 7426 KKYKIMSENFLTSIHILSVDAADVGEYQCKATNDVGSDTCVGSITLKAPPR--------- 7476
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FV +P + + A V G +V W K K + + I+I +
Sbjct: 7477 ------FVKKPSDVSTIVGEEVQLQATVEGAEPISVVWFKDKGEIVRESDNIWISYSENT 7530
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L+ ++G Y C N G E + + + E
Sbjct: 7531 ATLQFSRAETANAGKYTCQIKNDAGMQECSATVSILE 7567
Score = 326 bits (835), Expect = 5e-89
Identities = 195/582 (33%), Positives = 286/582 (49%), Gaps = 3/582 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ VT GD+ +L+C + GTPE+ W+K +L YK+ F N V+ L V +DSG
Sbjct: 7578 ITVTTGDTCTLECSVTGTPELTTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSG 7637
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y +N VG+ S + + V ++ +PPSF+R+L++ G VV EC V GS PISVS
Sbjct: 7638 VYSFEVQNPVGKDSCTASVQVSDRIVPPSFTRRLKETNGLSGSSVVMECKVYGSPPISVS 7697
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WF + + G QT+ DN L + + S AG Y+C ATN GS SA L +
Sbjct: 7698 WFHERNEISSGRKYQTTLTDNTCALTVNMLEESDAGNYTCIATNVAGSDECSAPLTV--- 7754
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
R PP F P+D + G + F V GT P V+W K + E+ G +S ++ A
Sbjct: 7755 REPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSTELVPGDTCNVSLEDSVAE 7814
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + VD +G+YTC NE GK SCT L +K P F KKL++ E +G L
Sbjct: 7815 LELFDVDTSQSGEYTCIVTNEAGKVSCTTHLYVK---APARFVKKLNDYSIE-KGKPLIL 7870
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
EG G+ PISV W KN + + P+ C IT + +L++ +++ DAG Y C + N +G
Sbjct: 7871 EGTYTGTPPISVTWKKNGINVTPSQRCNITTTERSAILEIPSSTVEDAGQYNCYIENTSG 7930
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
C++ I+I E PP F + L PV V+ G+ L C + G+ I + W K +++P+
Sbjct: 7931 KDSCSAQILILE---PPYFVRQLEPVKVTVGDSASLQCQLGGTPEIAVSWFKGDTKLRPT 7987
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
F N A L F V D+G+Y+C+A N G +S + +T
Sbjct: 7988 ATYKMHFRNNIATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLT--------------- 8032
Query: 1446 VDGKLFFVSEPQSIRVVEKTT---ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
V + S + +R V++T F V G +V W K R + I
Sbjct: 8033 VQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFK-DGRPVKDSPNIQASFL 8091
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
+ A L I T ++ +G Y C A N G S+ L + E K
Sbjct: 8092 DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGK 8133
Score = 319 bits (818), Expect = 5e-87
Identities = 189/573 (32%), Positives = 286/573 (49%), Gaps = 1/573 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G+S L+C+++G+PEI VSW++ D++L + Y M F ++VA L N+ + DSG+YIC
Sbjct: 6362 GESIHLECKISGSPEIKVSWFRNDSELHESWKYNMSFVDSVAVLTINEASAEDSGDYICE 6421
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A N VG+ S ST LT+ K PP F+++ + G VVF+C +SG+ P V W KD
Sbjct: 6422 AHNGVGDASCSTALTI---KAPPVFTQKPSPIGALKGSDVVFQCEISGTPPFEVVWVKDR 6478
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ ++ + + + A+L+I + + G+Y C ATN +GS + L E PP
Sbjct: 6479 KQVRSSKKFKITSKNFDASLHILNLEAADVGEYYCKATNEVGSDTCVCTLKFKE---PPR 6535
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE-IRSGGNYQISYLENSAHLTIL 737
F L+ +VG++ + V G QPI V W KD + IR N +IS+++N A L +
Sbjct: 6536 FVKKLSDTSTLVGDAVELRAVVEGFQPISVVWLKDKGDVIRESENTRISFVDNVATLQLG 6595
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+ D+G+Y C N+ G C+A L + E P+ + E + T GN+F LE V
Sbjct: 6596 SPEASDSGKYVCQIKNDAGMRECSAILTVLE----PARIIEKPEPMTVTTGNAFALECVV 6651
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
G+ +S W+K+ EI + ITF N L++ A M D GLY+ +V N G + C
Sbjct: 6652 TGTPELSAKWFKDGREIAADSKHHITFVNKVASLKIPCAEMSDKGLYSFEVKNSVGKSTC 6711
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
T S+ + + P F + L + G + L C V GS PI + W + G EI +C
Sbjct: 6712 TVSVHVSDRIVAPSFIRKLKDINAIVGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQ 6771
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF+ L + +D G Y C A+NVAGSD + +T +
Sbjct: 6772 SSFSENVCTLNLSFLEPSDTGTYTCVAANVAGSDECSAVLT---------------IQEP 6816
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F P S+ V+ T+ TF + + G P VKW KG R+L G I + +LE
Sbjct: 6817 PSFEQTPDSVEVLPGTSLTFTSVIRGTPPFKVKWFKGS-RELVSGESCSISLEDFVTELE 6875
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ + SG Y C+ N G +L V E
Sbjct: 6876 LFEVEPLQSGDYSCLVTNDAGSASCTAHLFVKE 6908
Score = 319 bits (817), Expect = 7e-87
Identities = 190/581 (32%), Positives = 285/581 (49%), Gaps = 3/581 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VTVG++ +L+C++AGTPE+ V WYK L + +K F N +++L V+ D+G Y
Sbjct: 5698 VTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVEKQDAGTY 5757
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
+ +N+VG+ S + + V ++ +PPSF+R+L+D +G + EC V+GS PISV+WF
Sbjct: 5758 TFQVQNNVGKSSCTAVVDVSDRMVPPSFTRRLKDTIGVLGTSCILECKVAGSSPISVAWF 5817
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
+ G QT+F DNV TL + D S G Y+C A N GS A L + E
Sbjct: 5818 HGKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANVAGSDECRAVLAVQE--- 5874
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP F P++ + G++ F + GT P KV W + RE+ G I + + A L
Sbjct: 5875 PPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGARELVKGDRCNIYFEDTVAELE 5934
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
+ VD +G+YTC N G+ SCT +L +KE P F KKLS+ E G S LE
Sbjct: 5935 LFNVDISQSGEYTCVVSNNAGQTSCTTRLFVKE---PAVFVKKLSDHSVE-PGKSIILES 5990
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
G+ PISV W K+ I P+ C I +L++ ++ DAG Y+C++ N+AG
Sbjct: 5991 TYKGTLPISVTWKKDGFNITPSEKCSIVTTEKTCILEILNSTKRDAGRYSCEIENEAGRD 6050
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
+C + + E PP F L P+ S G+ + L C V GS I + W K +++P+
Sbjct: 6051 VCEALVSTLE---PPYFVTELEPLEASVGDSVSLQCQVAGSPEITVSWYKGDTKLRPTPE 6107
Query: 1272 CSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVD 1451
F N A L F V D+G+Y CKA N G+ +SK+ +
Sbjct: 6108 YRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKT---------------VFRIQ 6152
Query: 1452 GKLFFVSEPQSIRVVEKTT---ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+ S + ++ +E+T T ++ G V W + L + +
Sbjct: 6153 ERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVSWYR-DGVLLRDDENLQTSFVDN 6211
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
A L+I T + SG Y C A N G S+ L E KK
Sbjct: 6212 VATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKK 6252
Score = 310 bits (793), Expect = 4e-84
Identities = 197/585 (33%), Positives = 278/585 (47%), Gaps = 12/585 (2%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G L+ GTP I V+W K + P+ + A L D+G+Y C
Sbjct: 7865 GKPLILEGTYTGTPPISVTWKKNGINVTPSQRCNITTTERSAILEIPSSTVEDAGQYNCY 7924
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
EN+ G+ S S + + E PP F RQL V+ TVG +C + G+ I+VSWFK
Sbjct: 7925 IENTSGKDSCSAQILILE---PPYFVRQLEPVKVTVGDSASLQCQLGGTPEIAVSWFKGD 7981
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
L+ + F +N+ATL Q D + +G+Y C A N +G SSS L + E + PP
Sbjct: 7982 TKLRPTATYKMHFRNNIATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPS 8041
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L V VG FEC V+G++PI V+W KD R ++ N Q S+L+N A L I +
Sbjct: 8042 FSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPVKDSPNIQASFLDNVATLNIFQ 8101
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
D+ GQY+C A N +G S +A+L + E PP F L+ V+ G S E V
Sbjct: 8102 TDRSFAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIPLA-PVDAVVGESADFECHVT 8160
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+QPI VAW K+N EI N +I++ N+ L + K GD+G YTC N+ G CT
Sbjct: 8161 GTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDSGQYTCYAVNEVGKDSCT 8220
Query: 1101 SSIVIKEPKKPPVFDQHLT-PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ + IKE PP F + L+ V +EG +L V GS+PI + W K EI P+ C
Sbjct: 8221 AQLNIKERLIPPSFTKKLSETVEETEGNSFKLEGRVAGSQPISVAWYKNNIEIHPTSNCE 8280
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
+F N T +L+ K DAG Y CK SN AGS S +
Sbjct: 8281 ITFKNNTLLLQIKRAGMDDAGLYTCKVSNDAGSALCTSSIV------------------- 8321
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKV-----------GGDPIPNVKWTKGKWRQLNQGGRIF 1604
+ EP+ V ++ A G +PI ++W K R++ R
Sbjct: 8322 ---IKEPKKPPVFDQHLTPVTASEGEFVQLSCHVWGSEPI-RIQWLKA-GREIKPSDRCS 8376
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
A LE++D TK D+G Y C A N G S + + ++
Sbjct: 8377 FSFANGTAVLELKDVTKADAGDYVCKASNVAGSDTSKSKVTIKDK 8421
Score = 309 bits (792), Expect = 5e-84
Identities = 189/585 (32%), Positives = 292/585 (49%), Gaps = 5/585 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ VT G++ +L+C + GTPE+ W+K ++ + + + F N VA+L + +D
Sbjct: 6636 PMTVTTGNAFALECVVTGTPELSAKWFKDGREIAADSKHHITFVNKVASLKIPCAEMSDK 6695
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y +NSVG+ + + + V ++ + PSF R+L+D+ VG VV EC VSGS PISV
Sbjct: 6696 GLYSFEVKNSVGKSTCTVSVHVSDRIVAPSFIRKLKDINAIVGASVVLECRVSGSAPISV 6755
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WF+DG + GP Q+SF +NV TLN+ + S G Y+C A N GS SA L + E
Sbjct: 6756 GWFQDGNEIVSGPKCQSSFSENVCTLNLSFLEPSDTGTYTCVAANVAGSDECSAVLTIQE 6815
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F+ V+ + G S F + GT P KV W K +RE+ SG + IS +
Sbjct: 6816 ---PPSFEQTPDSVEVLPGTSLTFTSVIRGTPPFKVKWFKGSRELVSGESCSISLEDFVT 6872
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + +V+ +G Y+C N+ G SCTA L +KE P +F K+L++ ET G+
Sbjct: 6873 ELELFEVEPLQSGDYSCLVTNDAGSASCTAHLFVKE---PATFVKRLADFSVET-GSPIV 6928
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE G+ PISV+W KN + + NC IT + +L++ +++ D Y+C + N+A
Sbjct: 6929 LEATFTGTPPISVSWMKNEFALTQSQNCSITMTEKSTILEILDSTIEDYAQYSCLIENEA 6988
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G +C + + + E PP F + L V GE + L C V G+ IRI W K +++
Sbjct: 6989 GQDICDAVVSVLE---PPYFIEPLEHVEAVIGEPITLQCKVDGTPEIRISWYKEHTKLRS 7045
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ F N A L V +D G+Y CKA N+ G+ S S +
Sbjct: 7046 APAYKMQFKNNVASLVINKVDHSDVGEYTCKAENIVGAVASSSVLV-------------- 7091
Query: 1443 XVDGKLFFVSEPQSIRVVEKT---TATFIAKVGGDPIPNVKWTKGKWRQLNQGG--RIFI 1607
+ + S + ++ V++T F ++ G V W K + F+
Sbjct: 7092 -IKERKLPPSFARKLKDVQETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFV 7150
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
H + A L+I T ++ G Y C A N G S+ L + E +
Sbjct: 7151 H---NVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLVLLEHE 7192
Score = 309 bits (792), Expect = 5e-84
Identities = 184/581 (31%), Positives = 286/581 (49%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ V G + + + GTP VSW+KG T+L P T + ++VA L VD++ S
Sbjct: 7766 PMDVLTGTNVTFTSIVKGTPPFSVSWFKGSTELVPGDTCNVSLEDSVAELELFDVDTSQS 7825
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C N G+VS +T L V K P F ++L D G P++ E +G+ PISV
Sbjct: 7826 GEYTCIVTNEAGKVSCTTHLYV---KAPARFVKKLNDYSIEKGKPLILEGTYTGTPPISV 7882
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+G + + + A L I + AGQY+C N G S SA++++ E
Sbjct: 7883 TWKKNGINVTPSQRCNITTTERSAILEIPSSTVEDAGQYNCYIENTSGKDSCSAQILILE 7942
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP+F L PV VG+SA +C + GT I V+W K + ++R Y++ + N A
Sbjct: 7943 ---PPYFVRQLEPVKVTVGDSASLQCQLGGTPEIAVSWFKGDTKLRPTATYKMHFRNNIA 7999
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L +VD D+G+Y C A N VG+ S + L ++E+ +PPSF+++L + V+ET G
Sbjct: 8000 TLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRD-VQETVGLPVV 8058
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
E V+GS+PISV+W+K+ + + N + +F +N L + + AG Y+C +N
Sbjct: 8059 FECAVSGSEPISVSWFKDGRPVKDSPNIQASFLDNVATLNIFQTDRSFAGQYSCTATNPI 8118
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GSA ++ +++ E K PP FD L PV GE CHV G++PI++ W K REI+
Sbjct: 8119 GSASSSARLILTEGKNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRS 8178
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S+ +A L V K D+G Y C A N G D+ +++
Sbjct: 8179 GGNYQISYLENSAHLTILKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPS----- 8233
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
F +++ E + +V G +V W K +++ I K +
Sbjct: 8234 ------FTKKLSETVEETEGNSFKLEGRVAGSQPISVAWYKNN-IEIHPTSNCEITFKNN 8286
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
L+I+ D+GLY C N G ++ + E KK
Sbjct: 8287 TLLLQIKRAGMDDAGLYTCKVSNDAGSALCTSSIVIKEPKK 8327
Score = 307 bits (787), Expect = 2e-83
Identities = 191/607 (31%), Positives = 287/607 (47%), Gaps = 1/607 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT D +L+C +AGTPE+ V W K ++ P+ + M F NNVA+ V DSG
Sbjct: 5133 VDVTERDPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSG 5192
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY + EN G S +L V +Q +PPSF+++L + + +G + EC VSGS PIS
Sbjct: 5193 EYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQ 5252
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKDG+ + + +N +L++ + Y+C +N G A+ S L + E
Sbjct: 5253 WFKDGKEISTSAKYRLVCHENTVSLDVNNLELEDTANYTCRVSNVAGDAACSGILTVKE- 5311
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F + A+ + +F+ + GT P K+ W KD+ E+ SG I +++
Sbjct: 5312 --PPSFLVKPERQQAIPDSTVEFKAVLKGTPPFKIKWFKDDVELASGPKCFIGLEGSTSF 5369
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + VD TGQYTC N+VG DSCT L + E PP F KKL T G+S RL
Sbjct: 5370 LNLYSVDASKTGQYTCQVTNDVGSDSCTTTLLVTE---PPKFVKKLEATKIVKAGDSARL 5426
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ GS I V WY+N E+ + + F ++ +LQ+ D G + C+ N AG
Sbjct: 5427 ECKITGSPDIRVVWYRNEHELPASDKYRMAFIDSVAVLQMNYLGTEDTGDFICEAQNPAG 5486
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
S C++ +++KE PPVF V + + + C + G+ P + W K R+++ S
Sbjct: 5487 STSCSTKVIVKE---PPVFSSFPPVVETLKNAEVSIECELSGTPPFEVVWYKDKRQLRSS 5543
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + N A + +V D G+Y CKA N GSDT V
Sbjct: 5544 KKYKIASKNFHASIHILNVDTLDIGEYHCKAQNEVGSDTCICIVKLKEPPR--------- 5594
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FVS+ S+ VV A A + G +V+W K K + + I I +
Sbjct: 5595 ------FVSKLNSLTVVAGEPAELQASIEGTQPISVQWLKEKEEVVRESENIRITFVENV 5648
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLK- 1802
A L+ ++G Y C N G E+ L V E + G + + +T L+
Sbjct: 5649 ATLQFSKAEPANAGKYICQIKNDGGMRENMATLTVLEPAVIVEKAGSMTVTVGETCTLEC 5708
Query: 1803 KGAGEEE 1823
K AG E
Sbjct: 5709 KVAGTPE 5715
Score = 302 bits (774), Expect = 6e-82
Identities = 183/574 (31%), Positives = 281/574 (48%), Gaps = 2/574 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G + +LQ + G+ I V+W KG ++ KM F N VA L+ V + +Y C
Sbjct: 3921 GQTVTLQAAVRGSEPISVTWMKGQEIIKEDGKIKMSFANGVAVLIIPDVQISFGDKYTCL 3980
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
AEN G +S L V+E P + +Q T G P E V+G+ + W+KDG
Sbjct: 3981 AENEAGSQTSVGELIVKE---PAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDG 4037
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
RPL + SF +NVA L + + +GQY+ +N +GS+S + + PF
Sbjct: 4038 RPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPF 4097
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F PL VD+VV + +C + G+ P++V+W KD +E+ S Y+I+++E +A L I +
Sbjct: 4098 FTKPLRNVDSVVSGTCRLDCKIAGSLPMRVSWFKDGKEVTSSDRYRIAFVEGTASLEISR 4157
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF-TKKLSETVEETEGNSFRLEGRV 917
VD D G +TC A N VG C+ L ++E PPSF TK S+ + G++ L+
Sbjct: 4158 VDMSDAGNFTCRATNSVGSKDCSGALIVQE---PPSFVTKPASKDI--LPGSAVFLKSTF 4212
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
GS P ++ W+K + E+ NC I + L++ D+G YTCKVSN AG+ C
Sbjct: 4213 QGSTPFTIRWFKGDKELVSGGNCYINKEALESSLELYSVKTTDSGTYTCKVSNVAGAVEC 4272
Query: 1098 TSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRC 1274
++++ +KE P F + L + +G+ QL+C V G+ PI+I W REIK S +
Sbjct: 4273 SANLFVKE---PATFVERLELSQLLKKGDTTQLACKVTGTPPIKITWFANDREIKESSKH 4329
Query: 1275 SFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDG 1454
SF TAVL D+ D+G+Y+C+A N AGSD S V
Sbjct: 4330 KMSFVESTAVLRLTDIAVEDSGEYMCEAQNEAGSDHCSS---------------ILIVKE 4374
Query: 1455 KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKL 1634
+F E + I V+++ +A+V G P + W K L G + + L
Sbjct: 4375 SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDN-TTLRSGRKYKTFIQDRLVSL 4433
Query: 1635 EIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+I D G Y+C N+ G + + + E
Sbjct: 4434 QILKFVAADVGKYQCRVTNEVGSSTCSARVTLRE 4467
Score = 301 bits (772), Expect = 1e-81
Identities = 188/576 (32%), Positives = 274/576 (47%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
+G S L+C++AG+ I V+W+ G TK+ A Y+ F +NV TL N +DS+D G Y C
Sbjct: 5796 LGTSCILECKVAGSSPISVAWFHGKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGSYTC 5855
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKD 377
A N G L VQE PPSF ++ ++ G + F + G+ P V WF+
Sbjct: 5856 VAANVAGSDECRAVLAVQE---PPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRG 5912
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
R L G F D VA L +F D S +G+Y+C +N G S + RL + E P
Sbjct: 5913 ARELVKGDRCNIYFEDTVAELELFNVDISQSGEYTCVVSNNAGQTSCTTRLFVKE---PA 5969
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F L+ G+S E GT PI V W KD I I E + L IL
Sbjct: 5970 VFVKKLSDHSVEPGKSIILESTYKGTLPISVTWKKDGFNITPSEKCSIVTTEKTCILEIL 6029
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
K D G+Y+C NE G+D C A ++ E PP F +L E +E + G+S L+ +V
Sbjct: 6030 NSTKRDAGRYSCEIENEAGRDVCEALVSTLE---PPYFVTEL-EPLEASVGDSVSLQCQV 6085
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
AGS I+V+WYK + ++ PT F NN L K ++ D+G YTCK N G+A
Sbjct: 6086 AGSPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASS 6145
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ I+E + PP F + L + + G + L+C + GS PI++ W + G ++ +
Sbjct: 6146 KTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVSWYRDGVLLRDDENLQ 6205
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF + A L+ + +G Y C ASN G+ +S +++T
Sbjct: 6206 TSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSP----------- 6254
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
FF +P SI ++ +A F V G + W+K +++ GG I G+ L
Sbjct: 6255 -FFDIKPVSIDIIAGESADFECHVTGAQPMRITWSKDN-KEIRPGGNYTITCVGNTPHLR 6312
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
I K DSG Y C A N G+ + L V E K
Sbjct: 6313 ILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPK 6348
Score = 297 bits (761), Expect = 2e-80
Identities = 186/579 (32%), Positives = 275/579 (47%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+ G L+C+L GTP VSW+K +LR YK+ N + ++ VD+ D
Sbjct: 7390 PVETLKGADVHLECELQGTPPFQVSWHKDKRELRSGKKYKIMSENFLTSIHILSVDAADV 7449
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+A N VG + +T+ K PP F ++ DV VG V + V G+EPISV
Sbjct: 7450 GEYQCKATNDVGSDTCVGSITL---KAPPRFVKKPSDVSTIVGEEVQLQATVEGAEPISV 7506
Query: 363 SWFKD-GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
WFKD G +++ NI S+ +N ATL + + + AG+Y+C N G SA + +
Sbjct: 7507 VWFKDKGEIVRESDNIWISYSENTATLQFSRAETANAGKYTCQIKNDAGMQECSATVSIL 7566
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E P + G++ EC VTGT + W KD +E+ S Y+IS+
Sbjct: 7567 E---PAAIVEKPESITVTTGDTCTLECSVTGTPELTTKWFKDGKELTSDNKYKISFFNKV 7623
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
+ L I+ V D+G Y+ N VGKDSCTA + + +R++PPSFT++L ET G+S
Sbjct: 7624 SGLKIINVAPSDSGVYSFEVQNPVGKDSCTASVQVSDRIVPPSFTRRLKET-NGLSGSSV 7682
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
+E +V GS PISV+W+ EI + T +N L V DAG YTC +N
Sbjct: 7683 VMECKVYGSPPISVSWFHERNEISSGRKYQTTLTDNTCALTVNMLEESDAGNYTCIATNV 7742
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS C++ + ++E PP F Q P+ V G + + V+G+ P + W K E+
Sbjct: 7743 AGSDECSAPLTVRE---PPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSTELV 7799
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
P D C+ S + A LE DV + +G+Y C +N AG + + +
Sbjct: 7800 PGDTCNVSLEDSVAELELFDVDTSQSGEYTCIVTNEAGKVSCTTHL-------------- 7845
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V FV + + + G P +V W K + R I
Sbjct: 7846 -YVKAPARFVKKLNDYSIEKGKPLILEGTYTGTPPISVTWKK-NGINVTPSQRCNITTTE 7903
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A LEI +T D+G Y C N G+ + + + E
Sbjct: 7904 RSAILEIPSSTVEDAGQYNCYIENTSGKDSCSAQILILE 7942
Score = 295 bits (754), Expect = 1e-79
Identities = 172/572 (30%), Positives = 285/572 (49%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
GD+ L C++ GTP I ++W+ D +++ ++ +KM F + A L + DSGEY+C
Sbjct: 4297 GDTTQLACKVTGTPPIKITWFANDREIKESSKHKMSFVESTAVLRLTDIAVEDSGEYMCE 4356
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A+N G S+ L V+E P F+++ + ++ V+ V+G+ P ++WFKD
Sbjct: 4357 AQNEAGSDHCSSILIVKES---PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDN 4413
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
L+ G +T D + +L I + + G+Y C TN +GS++ SAR+ L R PP
Sbjct: 4414 TTLRSGRKYKTFIQDRLVSLQILKFVAADVGKYQCRVTNEVGSSTCSARVTL---REPPT 4470
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F + ++ G +A F+ + G+ PI V W KDN EI N ++++ N A L +
Sbjct: 4471 FVKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDNEEITEDDNIRMTFENNVASLYLSG 4530
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
++ G+Y C A N+ G C A L++KE P+ + + +++ T+G+ L+ + +
Sbjct: 4531 IEVKHDGKYVCQAKNDAGIQRCFAVLSVKE----PATIIEEAVSIDVTQGDPATLQVKFS 4586
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G++ I+ W+K+ E+ +I+ + +L++ D+G YT +V ND G + C
Sbjct: 4587 GTKEITAKWFKDGQELTLGQKYKISVTDTVSILKIISTEKRDSGEYTFEVQNDVGRSSCK 4646
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSF 1280
+SI + + PP F + L + +G + L C V GS PI IQW K +EI S++ F
Sbjct: 4647 ASINVLDLIIPPSFTKKLKKMDSIKGSSIDLECIVAGSHPISIQWFKDDQEITASEKYKF 4706
Query: 1281 SFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKL 1460
SF + TA LE + +D+G Y C A+N AG + +T V
Sbjct: 4707 SFHDNTAFLEISQLEGSDSGTYTCSATNKAGHNQCSGHLT---------------VKEPP 4751
Query: 1461 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEI 1640
+F+ +PQS V T A VGG +KW K ++L+ G + + LE+
Sbjct: 4752 YFLEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDN-KELHSGAARSVWKDDTSTILEL 4810
Query: 1641 RDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
DSG Y C N G + +L V E
Sbjct: 4811 FSAKAADSGTYICQLSNDVGTATTKASLFVKE 4842
Score = 294 bits (752), Expect = 2e-79
Identities = 173/590 (29%), Positives = 284/590 (48%), Gaps = 1/590 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKL-RPTATYKMHFRNNVATLVFNQVDSNDS 182
V VG+ LQ + G I V W+K ++ R + + + N ATL F++ ++ ++
Sbjct: 7484 VSTIVGEEVQLQATVEGAEPISVVWFKDKGEIVRESDNIWISYSENTATLQFSRAETANA 7543
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y C+ +N G S +++ E P + + + T G EC+V+G+ ++
Sbjct: 7544 GKYTCQIKNDAGMQECSATVSILE---PAAIVEKPESITVTTGDTCTLECSVTGTPELTT 7600
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WFKDG+ L + SF + V+ L I S +G YS NP+G S +A + +++
Sbjct: 7601 KWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASVQVSD 7660
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F L + + G S EC V G+ PI V+W + EI SG YQ + +N+
Sbjct: 7661 RIVPPSFTRRLKETNGLSGSSVVMECKVYGSPPISVSWFHERNEISSGRKYQTTLTDNTC 7720
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
LT+ +++ D G YTC A N G D C+A L ++E PPSF +K + ++ G +
Sbjct: 7721 ALTVNMLEESDAGNYTCIATNVAGSDECSAPLTVRE---PPSFVQK-PDPMDVLTGTNVT 7776
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
V G+ P SV+W+K + E+ P C ++ +++ L++ +G YTC V+N+A
Sbjct: 7777 FTSIVKGTPPFSVSWFKGSTELVPGDTCNVSLEDSVAELELFDVDTSQSGEYTCIVTNEA 7836
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G CT+ + +K P + F + L ++ +G+ L L G+ PI + W K G + P
Sbjct: 7837 GKVSCTTHLYVKAPAR---FVKKLNDYSIEKGKPLILEGTYTGTPPISVTWKKNGINVTP 7893
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S RC+ + +A+LE T DAG Y C N +G D+ +++
Sbjct: 7894 SQRCNITTTERSAILEIPSSTVEDAGQYNCYIENTSGKDSCSAQILILEPP--------- 7944
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+FV + + ++V +A+ ++GG P V W KG +L +H + +
Sbjct: 7945 ------YFVRQLEPVKVTVGDSASLQCQLGGTPEIAVSWFKGD-TKLRPTATYKMHFRNN 7997
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLR 1772
A L DSG Y C A N GE+ S+ L V E+K LR
Sbjct: 7998 IATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR 8047
Score = 293 bits (750), Expect = 4e-79
Identities = 179/564 (31%), Positives = 268/564 (47%), Gaps = 1/564 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G L+ GTP I VSW K + L + + L D +Y
Sbjct: 6921 VETGSPIVLEATFTGTPPISVSWMKNEFALTQSQNCSITMTEKSTILEILDSTIEDYAQY 6980
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C EN G+ ++V E PP F L V+ +G P+ +C V G+ I +SW+
Sbjct: 6981 SCLIENEAGQDICDAVVSVLE---PPYFIEPLEHVEAVIGEPITLQCKVDGTPEIRISWY 7037
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K+ L+ P + F +NVA+L I + D S G+Y+C A N +G+ +SS+ L++ E +
Sbjct: 7038 KEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCKAENIVGAVASSSVLVIKERKL 7097
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP F L V +G FEC + G++P++V+W KD ++ N Q S++ N A L
Sbjct: 7098 PPSFARKLKDVQETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQ 7157
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
IL+ D+ GQY C A N +G S +A+L + E +PP F K +V+ G S +
Sbjct: 7158 ILQTDQSHVGQYNCSASNPLGTASSSAKLVLLEHEVPPFFDLK-PVSVDLALGESGSFKC 7216
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
V G+ P+ + W K+N EI P N ++T N L V K GDAG YTC SN AG
Sbjct: 7217 HVTGTAPMKITWAKDNREIRPGGNYKMTLVENTATLTVLKIGKGDAGQYTCYASNVAGKD 7276
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPV-TVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
C++ + ++E PP F + L P V + E + C + GS I++ W K EI+ S
Sbjct: 7277 SCSAHLGVQE---PPRFIKKLEPSRIVKQDESTRYECKIGGSPEIKVLWYKGETEIQESS 7333
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ SF + AVLE ++ D+GDY C+A N AGS +S + + V
Sbjct: 7334 KFRMSFVDSVAVLEMHGLSVEDSGDYTCEACNAAGSASSTTSL---------------KV 7378
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F +P + ++ ++ G P V W K K R+L G + I +
Sbjct: 7379 KEPPIFRKKPHPVETLKGADVHLECELQGTPPFQVSWHKDK-RELRSGKKYKIMSENFLT 7437
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHG 1700
+ I D G Y+C A N G
Sbjct: 7438 SIHILSVDAADVGEYQCKATNDVG 7461
Score = 291 bits (745), Expect = 1e-78
Identities = 198/665 (29%), Positives = 307/665 (46%), Gaps = 10/665 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ VT GD A+LQ + +GT EI W+K +L YK+ + V+ L + DSG
Sbjct: 4571 IDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGQKYKISVTDTVSILKIISTEKRDSG 4630
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY +N VG S + V + +PPSF+++L+ + G + EC V+GS PIS+
Sbjct: 4631 EYTFEVQNDVGRSSCKASINVLDLIIPPSFTKKLKKMDSIKGSSIDLECIVAGSHPISIQ 4690
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKD + + + SF DN A L I Q + S +G Y+C+ATN G S L + E
Sbjct: 4691 WFKDDQEITASEKYKFSFHDNTAFLEISQLEGSDSGTYTCSATNKAGHNQCSGHLTVKE- 4749
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP+F D + V GT P+ + W KDN+E+ SG + + S
Sbjct: 4750 --PPYFLEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTI 4807
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + D+G Y C N+VG + A L +KE PP F KK S + G S
Sbjct: 4808 LELFSAKAADSGTYICQLSNDVGTATTKASLFVKE---PPQFIKKPSPVLVLRNGQSTTF 4864
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ G+ I V+WY + EI I+F + Q+ A + ++G Y C+ NDAG
Sbjct: 4865 ECQITGTPEIRVSWYLDGNEITAVEKHGISFIDGLATFQISGARVENSGTYVCEAQNDAG 4924
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
+A C+ + +KE PP F + L PV V + ++L C V G+ P ++ WL+ +EI+ S
Sbjct: 4925 TASCSIELKVKE---PPTFIRELKPVEVVKDSDVELECEVMGTSPFQVTWLRNNKEIRSS 4981
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + + L +D GDY C SN GS + ++V+
Sbjct: 4982 KKYTLTDRVSVFNLNINRCDPSDTGDYQCIVSNEGGSCSCSARVSLKEPPS--------- 5032
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
F+ + ++I V K++ATF + V G P ++ W K + L++ + I +
Sbjct: 5033 ------FIKKIENITTVLKSSATFQSTVAGSPPISITWLKDD-QILDEDDNVHISFVNNV 5085
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE-------RKKQEKIEGD---LRA 1775
A L+IR SG Y C A N+ G L V E K + E D L
Sbjct: 5086 ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIIEKAKSVDVTERDPVTLEC 5145
Query: 1776 MLKKTPVLKKGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEE 1955
++ TP LK + ++ K + P Y + + FR +Q+ ++KQ E
Sbjct: 5146 VVAGTPELK--------VKWLKDGKQIVPSRYFSMSFENNVASFR--IQS--VMKQDSGE 5193
Query: 1956 ETHRL 1970
T ++
Sbjct: 5194 YTFKV 5198
Score = 290 bits (741), Expect = 4e-78
Identities = 177/576 (30%), Positives = 282/576 (48%), Gaps = 1/576 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V GDSA L+C++ G+P+I V WY+ + +L + Y+M F ++VA L N + + D+G++
Sbjct: 5418 VKAGDSARLECKITGSPDIRVVWYRNEHELPASDKYRMAFIDSVAVLQMNYLGTEDTGDF 5477
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
IC A+N G S ST + V+E PP FS V+ V EC +SG+ P V W+
Sbjct: 5478 ICEAQNPAGSTSCSTKVIVKE---PPVFSSFPPVVETLKNAEVSIECELSGTPPFEVVWY 5534
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KD R L+ + + + A+++I D G+Y C A N +GS + + + + +
Sbjct: 5535 KDKRQLRSSKKYKIASKNFHASIHILNVDTLDIGEYHCKAQNEVGSDTC---ICIVKLKE 5591
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI-RSGGNYQISYLENSAHL 728
PP F L + V GE A+ + + GTQPI V W K+ E+ R N +I+++EN A L
Sbjct: 5592 PPRFVSKLNSLTVVAGEPAELQASIEGTQPISVQWLKEKEEVVRESENIRITFVENVATL 5651
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
K + + G+Y C N+ G A L + E P+ + + ++ T G + LE
Sbjct: 5652 QFSKAEPANAGKYICQIKNDGGMRENMATLTVLE----PAVIVEKAGSMTVTVGETCTLE 5707
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+VAG+ +SV WYK+ + + + +F N L++ DAG YT +V N+ G
Sbjct: 5708 CKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVEKQDAGTYTFQVQNNVGK 5767
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
+ CT+ + + + PP F + L G L C V GS PI + W +I
Sbjct: 5768 SSCTAVVDVSDRMVPPSFTRRLKDTIGVLGTSCILECKVAGSSPISVAWFHGKTKIVSGA 5827
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ +F++ L+ + +D G Y C A+NVAGSD ++ + V
Sbjct: 5828 KYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANVAGSDECRAVLA---------------V 5872
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
FV EP+ + V+ TF + + G P V W +G R+L +G R I+ + A
Sbjct: 5873 QEPPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGA-RELVKGDRCNIYFEDTVA 5931
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+LE+ + + SG Y CV N G+ L V E
Sbjct: 5932 ELELFNVDISQSGEYTCVVSNNAGQTSCTTRLFVKE 5967
Score = 289 bits (740), Expect = 6e-78
Identities = 173/577 (29%), Positives = 278/577 (48%), Gaps = 1/577 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++V G + + + GTP V W++G +L ++F + VA L VD + S
Sbjct: 5884 PLEVLPGKNITFTSVIRGTPPFKVGWFRGARELVKGDRCNIYFEDTVAELELFNVDISQS 5943
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C N+ G+ S +T L V+E P F ++L D G ++ E G+ PISV
Sbjct: 5944 GEYTCVVSNNAGQTSCTTRLFVKE---PAVFVKKLSDHSVEPGKSIILESTYKGTLPISV 6000
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KDG + + L I + + AG+YSC N G A L
Sbjct: 6001 TWKKDGFNITPSEKCSIVTTEKTCILEILNSTKRDAGRYSCEIENEAGRDVCEA---LVS 6057
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP+F L P++A VG+S +C V G+ I V+W K + ++R Y+ + N A
Sbjct: 6058 TLEPPYFVTELEPLEASVGDSVSLQCQVAGSPEITVSWYKGDTKLRPTPEYRTYFTNNVA 6117
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L KV+ D+G+YTC A N +G S I+ER +PPSF ++L + +E+T G
Sbjct: 6118 TLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKD-IEQTVGLPVT 6176
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L R+ GS PI V+WY++ V + N + +F +N L++ + + +G Y+C SN
Sbjct: 6177 LTCRLNGSAPIQVSWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPL 6236
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G+A ++ + +EPKK P FD + + GE CHV G++P+RI W K +EI+P
Sbjct: 6237 GTASSSARLTAREPKKSPFFDIKPVSIDIIAGESADFECHVTGAQPMRITWSKDNKEIRP 6296
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ + T L V K D+G Y C+A+N G D ++++
Sbjct: 6297 GGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLS-------------- 6342
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFI-AKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V FV + ++ +V ++ + + K+ G P V W + +L++ + +
Sbjct: 6343 -VKEPPKFVKKLEASKVAKQGESIHLECKISGSPEIKVSWFRND-SELHESWKYNMSFVD 6400
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
A L I + + DSG Y C A N G+ + L +
Sbjct: 6401 SVAVLTINEASAEDSGDYICEAHNGVGDASCSTALTI 6437
Score = 286 bits (733), Expect = 4e-77
Identities = 179/578 (30%), Positives = 274/578 (47%), Gaps = 1/578 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKL-RPTATYKMHFRNNVATLVFNQVDSNDSGE 188
V G+ A LQ + GT I V W K ++ R + ++ F NVATL F++ + ++G+
Sbjct: 5604 VVAGEPAELQASIEGTQPISVQWLKEKEEVVRESENIRITFVENVATLQFSKAEPANAGK 5663
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
YIC+ +N G + LTV E P + + TVG EC V+G+ +SV W
Sbjct: 5664 YICQIKNDGGMRENMATLTVLE---PAVIVEKAGSMTVTVGETCTLECKVAGTPELSVEW 5720
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+KDG+ L + SF + +++L I ++ AG Y+ N +G +S +A + +++
Sbjct: 5721 YKDGKLLTSSQKHKFSFYNKISSLKILSVEKQDAGTY
Search to RefSeqHP_Rel49
BLASTX 2.2.24 [Aug-08-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MLTL1_0024_C11
(2001 letters)
Database: RefSeq49_HP.fasta
32,964 sequences; 18,297,164 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_596869.4| titin isoform N2-A [Homo sapiens]. 1215 0.0
Alignment gi|NP_114141.2| hemicentin-1 precursor [Homo sapiens]. 186 9e-47
Alignment gi|XP_001726994.1| PREDICTED: LOW QUALITY PROTEIN: hemicentin-2... 167 3e-41
Alignment gi|XP_001715206.1| PREDICTED: LOW QUALITY PROTEIN: hemicentin-2... 167 3e-41
Alignment gi|NP_005520.4| basement membrane-specific heparan sulfate prot... 157 4e-38
Alignment gi|NP_001139317.1| roundabout homolog 1 isoform d [Homo sapiens]. 156 8e-38
Alignment gi|NP_002932.1| roundabout homolog 1 isoform a precursor [Homo ... 156 8e-38
Alignment gi|NP_598334.2| roundabout homolog 1 isoform b [Homo sapiens]. 156 8e-38
Alignment gi|XP_003403872.1| PREDICTED: hemicentin-2-like [Homo sapiens]. 154 4e-37
Alignment gi|NP_001380.2| Down syndrome cell adhesion molecule isoform CH... 154 4e-37
>ref|NP_596869.4| titin isoform N2-A [Homo sapiens].
Length = 33423
Score = 1215 bits (3143), Expect = 0.0
Identities = 594/656 (90%), Positives = 628/656 (95%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PVKV+VGDSASLQCQLAGTPEIGVSWYKGDTKLRPT TYKMHFRNNVATLVFNQVD NDS
Sbjct: 7969 PVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDS 8028
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEYIC+AENSVGEVS+STFLTVQEQKLPPSFSRQLRDVQETVGLPVVF+CA+SGSEPISV
Sbjct: 8029 GEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISV 8088
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SW+KDG+PLKD PN+QTSFLDN ATLNIF+TDRS AGQYSCTATNPIGSASSSARLILTE
Sbjct: 8089 SWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTE 8148
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
G+NPPFFDI LAPVDAVVGESADFECHVTGTQPIKV+WAKD+REIRSGG YQISYLENSA
Sbjct: 8149 GKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSA 8208
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
HLT+LKVDKGD+GQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK+LSETVEETEGNSF+
Sbjct: 8209 HLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFK 8268
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LEGRVAGSQPI+VAWYKNN+EI PT+NCEITFKNN L+LQV+KA M DAGLYTCKVSNDA
Sbjct: 8269 LEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDA 8328
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGE++QLSCHV+GSEPIRIQWLKAGREIKP
Sbjct: 8329 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKP 8388
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
SDRCSFSFA+GTAVLE +DV KAD+GDYVCKASNVAGSDT+KSKVT
Sbjct: 8389 SDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKA 8448
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
VDG+LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR+FIHQKGD
Sbjct: 8449 AVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGD 8508
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLK 1802
EAKLEIRDTTKTDSGLYRCVAFN+HGEIESNVNLQV+ERKKQEKIEGDLRAMLKKTP+LK
Sbjct: 8509 EAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPILK 8568
Query: 1803 KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEEETHRL 1970
KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFE+LKQSQEEETHRL
Sbjct: 8569 KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRL 8624
Score = 504 bits (1297), Expect = e-142
Identities = 260/585 (44%), Positives = 363/585 (62%), Gaps = 7/585 (1%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++ VGDS SLQCQ+AGTPEI VSWYKGDTKLRPT Y+ +F NNVATLVFN+V+ NDS
Sbjct: 6087 PLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDS 6146
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+AENS+G SS T +QE++LPPSF+RQL+D+++TVGLPV C ++GS PI V
Sbjct: 6147 GEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQV 6206
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W++DG L+D N+QTSF+DNVATL I QTD S +GQYSC+A+NP+G+ASSSARL E
Sbjct: 6207 CWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTARE 6266
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ PFFDI +D + GESADFECHVTG QP+++ W+KDN+EIR GGNY I+ + N+
Sbjct: 6267 PKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTP 6326
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
HL ILKV KGD+GQYTC A N+VGKD C+AQL++KE PP F KKL + +G S +
Sbjct: 6327 HLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE---PPKFVKKLEASKVAKQGESIQ 6383
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE +++GS I V+W++N+ E+H + ++F N+ LL + +AS D+G Y C+ N
Sbjct: 6384 LECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGV 6443
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G A C++++ + K PPVF Q +PV +G + L C + G+ P + W+K ++++
Sbjct: 6444 GDASCSTALTV---KAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRN 6500
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + + L ++ +D G+Y CKA+N GSDT V
Sbjct: 6501 SKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVK-------------- 6546
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKV-------GGDPIPNVKWTKGKWRQLNQGGRI 1601
F P+ ++ + T+ V G PI +V W K + + +
Sbjct: 6547 -------FKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPI-SVVWLKDRGEVIRESENT 6598
Query: 1602 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
I + A L++ ++SG Y C N G E + L V E
Sbjct: 6599 RISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLE 6643
Score = 483 bits (1242), Expect = e-136
Identities = 255/578 (44%), Positives = 351/578 (60%), Gaps = 1/578 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ +G+ A+LQC++ GTPEI +SWYK TKLR YKM F+NNVA+LV N+VD +D G
Sbjct: 7029 VEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVG 7088
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY C+A+NSVG V+SS L ++ +KLPP F+R+L+DV ET+G PV FEC ++GSEP+ VS
Sbjct: 7089 EYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVS 7148
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+KDG LKD N+QTSF+ NVATL I QTD+S GQY+C+A+NP+G+ASSSA+LIL+E
Sbjct: 7149 WYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEH 7208
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PPFFD+ VD +GES F+CHVTGT PIK+ WAKDNREIR GGNY+++ +EN+A
Sbjct: 7209 EVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTAT 7268
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
LT+LKV KGD GQYTCYA N GKDSC+AQL ++E PP F KKL + + R
Sbjct: 7269 LTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE---PPRFIKKLEPSRIVKQDEFTRY 7325
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ GS I V WYK+ EI ++ ++F ++ +L++ S+ D+G YTC+ N AG
Sbjct: 7326 ECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAG 7385
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
SA ++S+ +KE PP+F + P+ +G + L C ++G+ P + W K RE++
Sbjct: 7386 SASSSTSLKVKE---PPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSG 7442
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ N + +V AD G+Y CKA+N GSDT +
Sbjct: 7443 KKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPR--------- 7493
Query: 1446 VDGKLFFVSEPQSI-RVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
FV + I VV K G +PI +V W K K + + I+I +
Sbjct: 7494 ------FVKKLSDISTVVGKEVQLQTTIEGAEPI-SVVWFKDKGEIVRESDNIWISYSEN 7546
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L+ ++G Y C N G E L V E
Sbjct: 7547 IATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE 7584
Score = 332 bits (851), Expect = 8e-91
Identities = 197/582 (33%), Positives = 289/582 (49%), Gaps = 3/582 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+KVT GD+ +L+C +AGTPE+ W+K +L YK+ F N V+ L V +DSG
Sbjct: 7595 IKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSG 7654
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y +N VG+ S + L V ++ +PPSF+R+L++ G VV EC V GS PISVS
Sbjct: 7655 VYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVS 7714
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WF +G + G QT+ DN L + + S +G Y+C ATN GS SA L +
Sbjct: 7715 WFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTV--- 7771
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
R PP F P+D + G + F V GT P V+W K + E+ G +S ++ A
Sbjct: 7772 REPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAE 7831
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + VD +G+YTC NE GK SCT L IK P F K+L++ E +G L
Sbjct: 7832 LELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK---APAKFVKRLNDYSIE-KGKPLIL 7887
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
EG G+ PISV W KN + + P+ C IT + +L++ +++ DAG Y C + N +G
Sbjct: 7888 EGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASG 7947
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
C++ I+I E PP F + L PV VS G+ L C + G+ I + W K +++P+
Sbjct: 7948 KDSCSAQILILE---PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPT 8004
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
F N A L F V D+G+Y+CKA N G ++ + +T
Sbjct: 8005 TTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLT--------------- 8049
Query: 1446 VDGKLFFVSEPQSIRVVEKTT---ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
V + S + +R V++T F + G +V W K + L +
Sbjct: 8050 VQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYK-DGKPLKDSPNVQTSFL 8108
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
+ A L I T ++ +G Y C A N G S+ L + E K
Sbjct: 8109 DNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGK 8150
Score = 317 bits (812), Expect = 3e-86
Identities = 190/573 (33%), Positives = 285/573 (49%), Gaps = 1/573 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G+S L+C+++G+PEI VSW++ D++L + Y M F N+VA L N+ + DSG+YIC
Sbjct: 6379 GESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICE 6438
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A N VG+ S ST LTV K PP F+++ V G V+ +C +SG+ P V W KD
Sbjct: 6439 AHNGVGDASCSTALTV---KAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDR 6495
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ +++ + + +L+I + S G+Y C ATN +GS + S + E PP
Sbjct: 6496 KQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKE---PPR 6552
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE-IRSGGNYQISYLENSAHLTIL 737
F L+ ++G++ + V G QPI V W KD E IR N +IS+++N A L +
Sbjct: 6553 FVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLG 6612
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+ ++G+Y C N+ G C+A L + E P+ + E + T GN F LE V
Sbjct: 6613 SPEASNSGKYICQIKNDAGMRECSAVLTVLE----PARIIEKPEPMTVTTGNPFALECVV 6668
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
G+ +S W+K+ E+ + ITF N L++ A M D GLY+ +V N G + C
Sbjct: 6669 TGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNC 6728
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
T S+ + + PP F + L V G + L C V GS PI + W + G EI +C
Sbjct: 6729 TVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQ 6788
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF+ L + +D G Y C A+NVAGSD + +T V
Sbjct: 6789 SSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLT---------------VQEP 6833
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F P S+ V+ + TF + + G P VKW KG R+L G I + +LE
Sbjct: 6834 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGS-RELVPGESCNISLEDFVTELE 6892
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ + +SG Y C+ N G +L V E
Sbjct: 6893 LFEVQPLESGDYSCLVTNDAGSASCTTHLFVKE 6925
Score = 312 bits (800), Expect = 6e-85
Identities = 185/584 (31%), Positives = 288/584 (49%), Gaps = 3/584 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ VTVG++ +L+C++AGTPE+ V WYK L + +K F N +++L V+ D+
Sbjct: 5712 PMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDA 5771
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y + +N+VG+ S + + V ++ +PPSF+R+L++ +G + EC V+GS PISV
Sbjct: 5772 GTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISV 5831
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+WF + + G QT+F DNV TL + D S G Y+C A N GS A L + E
Sbjct: 5832 AWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE 5891
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F P++ + G++ F + GT P KV W + RE+ G I + + A
Sbjct: 5892 ---PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVA 5948
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + +D +G+YTC N G+ SCT +L +KE P +F K+LS+ E G S
Sbjct: 5949 ELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE---PAAFLKRLSDHSVE-PGKSII 6004
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE G+ PISV W K+ I + C I +L++ ++ DAG Y+C++ N+A
Sbjct: 6005 LESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEA 6064
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G +C + + E PP F L P+ + G+ + L C V G+ I + W K +++P
Sbjct: 6065 GRDVCGALVSTLE---PPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRP 6121
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ F N A L F V D+G+Y CKA N G+ +SK+
Sbjct: 6122 TPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKT---------------VF 6166
Query: 1443 XVDGKLFFVSEPQSIRVVEKTT---ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
+ + S + ++ +E+T T ++ G V W + L +
Sbjct: 6167 RIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYR-DGVLLRDDENLQTSF 6225
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
+ A L+I T + SG Y C A N G S+ L E KK
Sbjct: 6226 VDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKK 6269
Score = 307 bits (787), Expect = 2e-83
Identities = 186/573 (32%), Positives = 284/573 (49%), Gaps = 1/573 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G + +LQ + G+ I V+W KG +R KM F N VA L+ V + G+Y C
Sbjct: 3938 GQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCL 3997
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
AEN G +S L V+E P + +Q T G P E V+G+ + W+KDG
Sbjct: 3998 AENEAGSQTSVGELIVKE---PAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDG 4054
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
RPL + SF +NVA L + + +GQY+ +N +GS+S + + PF
Sbjct: 4055 RPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPF 4114
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F PL VD+VV + +C + G+ P++V+W KD +EI + Y+I+++E +A L I++
Sbjct: 4115 FTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIR 4174
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
VD D G +TC A N VG + L ++E PPSF K + + G++ L+
Sbjct: 4175 VDMNDAGNFTCRATNSVGSKDSSGALIVQE---PPSFVTK-PGSKDVLPGSAVCLKSTFQ 4230
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
GS P+++ W+K N E+ +C IT + L++ D+G YTCKVSN AG C+
Sbjct: 4231 GSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECS 4290
Query: 1101 SSIVIKEPKKPPVFDQHLTP-VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+++ +KE P F + L P + +G+ QL+C V G+ PI+I W REIK S +
Sbjct: 4291 ANLFVKE---PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHR 4347
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF TAVL DV D+G+Y+C+A N AGSD S V V
Sbjct: 4348 MSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIV---------------IVKES 4392
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
+F E + I V+++ +A+V G P + W K L G + + L+
Sbjct: 4393 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDN-TILRSGRKYKTFIQDHLVSLQ 4451
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
I D+G Y+C N+ G + + + E
Sbjct: 4452 ILKFVAADAGEYQCRVTNEVGSSICSARVTLRE 4484
Score = 303 bits (775), Expect = 5e-82
Identities = 188/607 (30%), Positives = 288/607 (47%), Gaps = 1/607 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT D +L+C +AGTPE+ V W K ++ P+ + M F NNVA+ V DSG
Sbjct: 5150 VDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSG 5209
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y + EN G S +L V +Q +PPSF+++L + + +G + EC VSGS PIS
Sbjct: 5210 QYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQ 5269
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKDG+ + + + +L + + Y+C +N G + S L + E
Sbjct: 5270 WFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE- 5328
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F + A+ + +F+ + GT P K+ W KD+ E+ SG I +++
Sbjct: 5329 --PPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSF 5386
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + VD TGQYTC+ N+VG DSCT L + E PP F KKL + G+S RL
Sbjct: 5387 LNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTE---PPKFVKKLEASKIVKAGDSSRL 5443
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++AGS I V W++N E+ + +TF ++ ++Q+ S D+G + C+ N AG
Sbjct: 5444 ECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAG 5503
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
S C++ +++KE PPVF V + + L C + G+ P + W K R+++ S
Sbjct: 5504 STSCSTKVIVKE---PPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSS 5560
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + N + +V +D G+Y CKA N GSDT V
Sbjct: 5561 KKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPR--------- 5611
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FVS+ S+ VV A A + G V+W K K + + I I +
Sbjct: 5612 ------FVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENV 5665
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLK- 1802
A L+ ++G Y C N G E+ L V E + G + + +T L+
Sbjct: 5666 ATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLEC 5725
Query: 1803 KGAGEEE 1823
K AG E
Sbjct: 5726 KVAGTPE 5732
Score = 302 bits (773), Expect = 9e-82
Identities = 186/582 (31%), Positives = 284/582 (48%), Gaps = 2/582 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ VT G+ +L+C + GTPE+ W+K +L + + + F N VA+L + +D
Sbjct: 6653 PMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDK 6712
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y +NSVG+ + + + V ++ +PPSF R+L+DV +G VV EC VSGS PISV
Sbjct: 6713 GLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISV 6772
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WF+DG + GP Q+SF +NV TLN+ + S G Y+C A N GS SA L + E
Sbjct: 6773 GWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQE 6832
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F+ V+ + G S F + GT P KV W K +RE+ G + IS +
Sbjct: 6833 ---PPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVT 6889
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + +V ++G Y+C N+ G SCT L +KE P +F K+L++ ET G+
Sbjct: 6890 ELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKE---PATFVKRLADFSVET-GSPIV 6945
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE G+ PISV+W K+ I + C IT + +L++ ++++ D Y+C + N+A
Sbjct: 6946 LEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEA 7005
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G +C + + + E PP F + L V GE L C V G+ IRI W K +++
Sbjct: 7006 GQDICEALVSVLE---PPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRS 7062
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ F N A L V +D G+Y CKA N G+ S + +
Sbjct: 7063 APAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPP------ 7116
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGG--RIFIHQK 1616
FF + + + F ++ G V W K + F+H
Sbjct: 7117 ------FFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVH-- 7168
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
+ A L+I T ++ G Y C A N G S+ L ++E +
Sbjct: 7169 -NVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE 7209
Score = 301 bits (771), Expect = 1e-81
Identities = 183/564 (32%), Positives = 272/564 (48%), Gaps = 1/564 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G L+ GTP I VSW K + + + + L + D +Y
Sbjct: 6938 VETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQY 6997
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C EN G+ ++V E PP F L V+ +G P +C V G+ I +SW+
Sbjct: 6998 SCLIENEAGQDICEALVSVLE---PPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWY 7054
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K+ L+ P + F +NVA+L I + D S G+YSC A N +G+ +SSA L++ +
Sbjct: 7055 KEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKL 7114
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PPFF L V +G FEC + G++P++V+W KD ++ N Q S++ N A L
Sbjct: 7115 PPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQ 7174
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
IL+ D+ GQY C A N +G S +A+L + E +PP F K +V+ G S +
Sbjct: 7175 ILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLK-PVSVDLALGESGTFKC 7233
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
V G+ PI + W K+N EI P N ++T N L V K GDAG YTC SN AG
Sbjct: 7234 HVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKD 7293
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPV-TVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
C++ + ++E PP F + L P V + EF + C + GS I++ W K EI+ S
Sbjct: 7294 SCSAQLGVQE---PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESS 7350
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ SF + AVLE +++ D+GDY C+A N AGS +S + + V
Sbjct: 7351 KFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSL---------------KV 7395
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F +P I ++ ++ G P +V W K K R+L G + I +
Sbjct: 7396 KEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDK-RELRSGKKYKIMSENFLT 7454
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHG 1700
+ I + D G Y+C A N G
Sbjct: 7455 SIHILNVDAADIGEYQCKATNDVG 7478
Score = 301 bits (771), Expect = 1e-81
Identities = 187/579 (32%), Positives = 273/579 (47%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++ G L+C+L GTP VSWYK +LR YK+ N + ++ VD+ D
Sbjct: 7407 PIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADI 7466
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+A N VG S T + K PP F ++L D+ VG V + + G+EPISV
Sbjct: 7467 GEYQCKATNDVG---SDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISV 7523
Query: 363 SWFKD-GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
WFKD G +++ NI S+ +N+ATL + + + AG+Y+C N G A L +
Sbjct: 7524 VWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVL 7583
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E P + G++ EC V GT + W KD +E+ S Y+IS+
Sbjct: 7584 E---PATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKV 7640
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
+ L I+ V D+G Y+ N VGKDSCTA L + +R +PPSFT+KL ET G+S
Sbjct: 7641 SGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKET-NGLSGSSV 7699
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
+E +V GS PISV+W+ EI + T +N L V D+G YTC +N
Sbjct: 7700 VMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNM 7759
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS C++ + ++E PP F Q P+ V G + + V+G+ P + W K E+
Sbjct: 7760 AGSDECSAPLTVRE---PPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELV 7816
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
P DRC+ S + A LE DV + +G+Y C SN AG + + +
Sbjct: 7817 PGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHL-------------- 7862
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
+ FV + + G P +V W K + R I
Sbjct: 7863 -YIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKK-NGINVTPSQRCNITTTE 7920
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A LEI +T D+G Y C N G+ + + + E
Sbjct: 7921 KSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILE 7959
Score = 301 bits (771), Expect = 1e-81
Identities = 188/574 (32%), Positives = 273/574 (47%), Gaps = 1/574 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G L+ GTP I V+W K + P+ + A L D+G+Y C
Sbjct: 7882 GKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCY 7941
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
EN+ G+ S S + + E PP F +QL V+ +VG +C ++G+ I VSW+K
Sbjct: 7942 IENASGKDSCSAQILILE---PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGD 7998
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
L+ + F +NVATL Q D + +G+Y C A N +G S+S L + E + PP
Sbjct: 7999 TKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPS 8058
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L V VG F+C ++G++PI V+W KD + ++ N Q S+L+N+A L I K
Sbjct: 8059 FSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFK 8118
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
D+ GQY+C A N +G S +A+L + E PP F +L+ V+ G S E V
Sbjct: 8119 TDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLA-PVDAVVGESADFECHVT 8177
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+QPI V+W K++ EI +I++ N+ L V K GD+G YTC N+ G CT
Sbjct: 8178 GTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCT 8237
Query: 1101 SSIVIKEPKKPPVFDQHLT-PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ + IKE PP F + L+ V +EG +L V GS+PI + W K EI+P+ C
Sbjct: 8238 AQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCE 8297
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
+F N T VL+ + DAG Y CK SN AGS S +
Sbjct: 8298 ITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP----------- 8346
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F + V E V G ++W K R++ R A LE
Sbjct: 8347 -VFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKA-GREIKPSDRCSFSFASGTAVLE 8404
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
+RD K DSG Y C A N G + + + ++
Sbjct: 8405 LRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDK 8438
Score = 298 bits (762), Expect = 2e-80
Identities = 178/590 (30%), Positives = 284/590 (48%), Gaps = 1/590 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKL-RPTATYKMHFRNNVATLVFNQVDSNDS 182
+ VG LQ + G I V W+K ++ R + + + N+ATL F++V+ ++
Sbjct: 7501 ISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANA 7560
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y C+ +N G L+V E P + + ++ T G EC V+G+ +S
Sbjct: 7561 GKYTCQIKNDAGMQECFATLSVLE---PATIVEKPESIKVTTGDTCTLECTVAGTPELST 7617
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WFKDG+ L + SF + V+ L I S +G YS NP+G S +A L +++
Sbjct: 7618 KWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSD 7677
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F L + + G S EC V G+ PI V+W + EI SG YQ + +N+
Sbjct: 7678 RTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTC 7737
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
LT+ +++ D+G YTC A N G D C+A L ++E PPSF +K + ++ G +
Sbjct: 7738 ALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVRE---PPSFVQK-PDPMDVLTGTNVT 7793
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
V G+ P SV+W+K + E+ P C ++ +++ L++ +G YTC VSN+A
Sbjct: 7794 FTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEA 7853
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G A CT+ + IK P K F + L ++ +G+ L L G+ PI + W K G + P
Sbjct: 7854 GKASCTTHLYIKAPAK---FVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTP 7910
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S RC+ + +A+LE T DAG Y C N +G D+ +++
Sbjct: 7911 SQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPP--------- 7961
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+FV + + ++V +A+ ++ G P V W KG +L +H + +
Sbjct: 7962 ------YFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGD-TKLRPTTTYKMHFRNN 8014
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLR 1772
A L DSG Y C A N GE+ ++ L V E+K LR
Sbjct: 8015 VATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLR 8064
Score = 290 bits (742), Expect = 3e-78
Identities = 180/576 (31%), Positives = 282/576 (48%), Gaps = 1/576 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V GDS+ L+C++AG+PEI V W++ + +L + Y+M F ++VA + N + + DSG++
Sbjct: 5435 VKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDF 5494
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
IC A+N G S ST + V+E PP FS V+ V EC +SG+ P V W+
Sbjct: 5495 ICEAQNPAGSTSCSTKVIVKE---PPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWY 5551
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KD R L+ + + + +++I D S G+Y C A N +GS + + L E
Sbjct: 5552 KDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKE--- 5608
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE-IRSGGNYQISYLENSAHL 728
PP F L + V GE A+ + + G QPI V W K+ E IR N +I+++EN A L
Sbjct: 5609 PPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATL 5668
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
K + + G+Y C N+ G A L + E P+ + + + T G + LE
Sbjct: 5669 QFAKAEPANAGKYICQIKNDGGMRENMATLMVLE----PAVIVEKAGPMTVTVGETCTLE 5724
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+VAG+ +SV WYK+ + + + +F N L++ DAG YT +V N+ G
Sbjct: 5725 CKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGK 5784
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
+ CT+ + + + PP F + L G L C V GS PI + W +I
Sbjct: 5785 SSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGA 5844
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ +F++ L+ + +D G+Y C A+NVAGSD ++ +T V
Sbjct: 5845 KYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLT---------------V 5889
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
FV EP+ + V+ TF + + G P V W +G R+L +G R I+ + A
Sbjct: 5890 QEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGA-RELVKGDRCNIYFEDTVA 5948
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+LE+ + + SG Y CV N G+ L V E
Sbjct: 5949 ELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE 5984
Score = 286 bits (732), Expect = 5e-77
Identities = 187/609 (30%), Positives = 284/609 (46%), Gaps = 10/609 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ VT GD A+LQ + +GT EI W+K +L + YK+ + V+ L + DSG
Sbjct: 4588 IDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSG 4647
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY +N VG S + V + +PPSF+++L+ + G + EC V+GS PIS+
Sbjct: 4648 EYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQ 4707
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKD + + + SF DN A L I Q + + +G Y+C+ATN G S L + E
Sbjct: 4708 WFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE- 4766
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP+F D + V GT P+ + W KDN+E+ SG + + S
Sbjct: 4767 --PPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTS 4824
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + D+G Y C N+VG + A L +KE PP F KK S + G S
Sbjct: 4825 LELFAAKATDSGTYICQLSNDVGTATSKATLFVKE---PPQFIKKPSPVLVLRNGQSTTF 4881
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ G+ I V+WY + EI I+F + Q+ A + ++G Y C+ NDAG
Sbjct: 4882 ECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAG 4941
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
+A C+ + +KE PP F + L PV V + ++L C V G+ P + WLK REI+ S
Sbjct: 4942 TASCSIELKVKE---PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSS 4998
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + + L +D G+Y C SN GS + ++V
Sbjct: 4999 KKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPS--------- 5049
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
F+ + ++ V K++ATF + V G P ++ W K + L++ ++I
Sbjct: 5050 ------FIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDD-QILDEDDNVYISFVDSV 5102
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNL------QVNERKKQ----EKIEGDLRA 1775
A L+IR SG Y C A N+ G L Q+ E+ K EK L
Sbjct: 5103 ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLEC 5162
Query: 1776 MLKKTPVLK 1802
++ TP LK
Sbjct: 5163 VVAGTPELK 5171
Score = 283 bits (725), Expect = 3e-76
Identities = 178/593 (30%), Positives = 286/593 (48%), Gaps = 3/593 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSN--DSG 185
V G S L+ GT I V+W K + T + K + T + ++S D+G
Sbjct: 5997 VEPGKSIILESTYTGTLPISVTWKKDGFNI--TTSEKCNIVTTEKTCILEILNSTKRDAG 6054
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y C EN G ++ E PP F +L ++ VG V +C V+G+ I+VS
Sbjct: 6055 QYSCEIENEAGRDVCGALVSTLE---PPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVS 6111
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+K L+ P +T F +NVATL + + + +G+Y+C A N IG+ASS + E
Sbjct: 6112 WYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER 6171
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
+ PP F L ++ VG C + G+ PI+V W +D +R N Q S+++N A
Sbjct: 6172 QLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVAT 6231
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L IL+ D +GQY+C A N +G S +A+L +E P F K +++ G S
Sbjct: 6232 LKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIK-PVSIDVIAGESADF 6290
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E V G+QP+ + W K+N EI P N IT N L++ K GD+G YTC+ +ND G
Sbjct: 6291 ECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVG 6350
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVS-EGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
+C++ + +KE PP F + L V+ +GE +QL C + GS I++ W + E+
Sbjct: 6351 KDMCSAQLSVKE---PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHE 6407
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + SF N A+L + + D+GDY+C+A N G + + +T
Sbjct: 6408 SWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALT-------------- 6453
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
V F +P + ++ + ++ G P V W K + +Q+ + I K
Sbjct: 6454 -VKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDR-KQVRNSKKFKITSKHF 6511
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAML 1781
+ L I + +D G Y C A N+ G + +++ E + K D ++
Sbjct: 6512 DTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLI 6564
Score = 282 bits (722), Expect = 7e-76
Identities = 164/573 (28%), Positives = 283/573 (49%), Gaps = 1/573 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G +A+ Q L G+ I V+W K ++ +M F NNVA+L + ++ G+Y+C+
Sbjct: 4500 GGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQ 4559
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A+N G S L+V+E P + + + + T G P + SG++ I+ WFKDG
Sbjct: 4560 AKNDAGIQRCSALLSVKE---PATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDG 4616
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ L G + S D V+ L I T++ +G+Y+ N +G +S AR+ + + PP
Sbjct: 4617 QELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPS 4676
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L +D++ G D EC V G+ PI + W KD++EI + Y+ S+ +N+A L I +
Sbjct: 4677 FTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQ 4736
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
++ D+G YTC A N+ G + C+ L +KE PP F +K ++ + +L+ V
Sbjct: 4737 LEGTDSGTYTCSATNKAGHNQCSGHLTVKE---PPYFVEK-PQSQDVNPNTRVQLKALVG 4792
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+ P+++ W+K+N E+H A + + + L++ A D+G Y C++SND G+A
Sbjct: 4793 GTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSK 4852
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTV-SEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+++ +KE PP F + +PV V G+ C + G+ IR+ W G EI +
Sbjct: 4853 ATLFVKE---PPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHG 4909
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF +G A + ++G YVC+A N AG+ + ++ V
Sbjct: 4910 ISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIEL---------------KVKEP 4954
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F+ E + + VV+ + +V G P V W K R++ + + + L
Sbjct: 4955 PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNN-REIRSSKKYTLTDRVSVFNLH 5013
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
I +D+G Y+C+ N+ G + + + E
Sbjct: 5014 ITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE 5046
Score = 281 bits (718), Expect = 2e-75
Identities = 171/577 (29%), Positives = 278/577 (48%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++VT GD A+L+ +AGTPE+ WYK L + Y++ F+NNVA L F + +DSG
Sbjct: 4026 IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSG 4085
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y N VG S T TV ++ + P F++ LR+V V +C ++GS P+ VS
Sbjct: 4086 QYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVS 4145
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKDG+ + + +F++ A+L I + D + AG ++C ATN +GS SS LI+ E
Sbjct: 4146 WFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQE- 4204
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F D + G + + G+ P+ + W K N+E+ SGG+ I+ +
Sbjct: 4205 --PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESS 4262
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + V D+G YTC N G C+A L +KE P +F +KL + +G++ +L
Sbjct: 4263 LELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE---PATFVEKLEPSQLLKKGDATQL 4319
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+V G+ PI + W+ N+ EI ++ ++F + +L++ + D+G Y C+ N+AG
Sbjct: 4320 ACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAG 4379
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
S C+S +++KE P F + P+ V + + L V G+ P I W K ++
Sbjct: 4380 SDHCSSIVIVKE---SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSG 4436
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + L+ ADAG+Y C+ +N GS ++VT
Sbjct: 4437 RKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPS--------- 4487
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
F+ + +S + TA F A + G V W K ++ + I + + +
Sbjct: 4488 ------FIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDS-DEITEDDNIRMTFENNV 4540
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L + G Y C A N G + L V E
Sbjct: 4541 ASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE 4577
Score = 281 bits (718), Expect = 2e-75
Identities = 172/559 (30%), Positives = 264/559 (47%), Gaps = 1/559 (0%)
Frame = +3
Query: 27 SASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAE 206
SA+ Q +AG+P I ++W K D L + F ++VATL VD+ SG Y C+A+
Sbjct: 5064 SATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAK 5123
Query: 207 NSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRP 386
N G FL VQE P + + V T P+ EC V+G+ + V W KDG+
Sbjct: 5124 NESGVERCYAFLLVQE---PAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQ 5180
Query: 387 LKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFD 566
+ SF +NVA+ I + +GQY+ N GS+S A L + + PP F
Sbjct: 5181 IVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFT 5240
Query: 567 IPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVD 746
L +D V+G S EC V+G+ PI W KD +EI + Y++ E S L + ++
Sbjct: 5241 KKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLE 5300
Query: 747 KGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGS 926
DT YTC N G D+C+ L +KE PPSF K + ++ + + G+
Sbjct: 5301 LEDTANYTCKVSNVAGDDACSGILTVKE---PPSFLVKPGRQ-QAIPDSTVEFKAILKGT 5356
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS 1106
P + W+K++VE+ C I + + L + G YTC V+ND GS CT+
Sbjct: 5357 PPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTM 5416
Query: 1107 IVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFS 1283
+++ E PP F + L V G+ +L C + GS IR+ W + E+ SD+ +
Sbjct: 5417 LLVTE---PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMT 5473
Query: 1284 FANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLF 1463
F + AV++ +++ D+GD++C+A N AGS + +KV V
Sbjct: 5474 FIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKV---------------IVKEPPV 5518
Query: 1464 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIR 1643
F S P + ++ + ++ G P V W K K RQL + I K + I
Sbjct: 5519 FSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDK-RQLRSSKKYKIASKNFHTSIHIL 5577
Query: 1644 DTTKTDSGLYRCVAFNKHG 1700
+ +D G Y C A N+ G
Sbjct: 5578 NVDTSDIGEYHCKAQNEVG 5596
Score = 276 bits (707), Expect = 4e-74
Identities = 176/578 (30%), Positives = 269/578 (46%), Gaps = 1/578 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTK-LRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
V G+ A LQ + G I V W K + +R + ++ F NVATL F + + ++G+
Sbjct: 5621 VVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGK 5680
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
YIC+ +N G + L V E P + + TVG EC V+G+ +SV W
Sbjct: 5681 YICQIKNDGGMRENMATLMVLE---PAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEW 5737
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+KDG+ L + SF + +++L I +R AG Y+ N +G +S +A + +++
Sbjct: 5738 YKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRA 5797
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP F L V+G S EC V G+ PI VAW + +I SG YQ ++ +N L
Sbjct: 5798 VPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTL 5857
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPTFQVQNNVGKSSCTAVVDVSDRM 5780
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP F L V+G S EC V G+ PI VAW +I SG YQ ++ +N L
Sbjct: 5781 VPPSFTRRLKDTIGVLGTSCILECKVAGSSPISVAWFHGKTKIVSGAKYQTTFSDNVCTL 5840
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
+ +D D G YTC A N G D C A L ++E PPSF K+ E +E G +
Sbjct: 5841 QLNSLDSSDMGSYTCVAANVAGSDECRAVLAVQE---PPSFVKE-PEPLEVLPGKNITFT 5896
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+ G+ P V W++ E+ C I F++ L++ + +G YTC VSN+AG
Sbjct: 5897 SVIRGTPPFKVGWFRGARELVKGDRCNIYFEDTVAELELFNVDISQSGEYTCVVSNNAGQ 5956
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
CT+ + +KEP VF + L+ +V G+ + L +G+ PI + W K G I PS+
Sbjct: 5957 TSCTTRLFVKEPA---VFVKKLSDHSVEPGKSIILESTYKGTLPISVTWKKDGFNITPSE 6013
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+CS T +LE + TK DAG Y C+ N AG D ++ V+
Sbjct: 6014 KCSIVTTEKTCILEILNSTKRDAGRYSCEIENEAGRDVCEALVSTLEPP----------- 6062
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
+FV+E + + + + +V G P V W KG +L + + A
Sbjct: 6063 ----YFVTELEPLEASVGDSVSLQCQVAGSPEITVSWYKGD-TKLRPTPEYRTYFTNNVA 6117
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
L DSG Y C A N G S ++ ER+
Sbjct: 6118 TLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQ 6155
Score = 286 bits (733), Expect = 4e-77
Identities = 175/564 (31%), Positives = 272/564 (48%), Gaps = 1/564 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G S L+ GT I V+W K + P+ + L D+G Y
Sbjct: 5980 VEPGKSIILESTYKGTLPISVTWKKDGFNITPSEKCSIVTTEKTCILEILNSTKRDAGRY 6039
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C EN G ++ E PP F +L ++ +VG V +C V+GS I+VSW+
Sbjct: 6040 SCEIENEAGRDVCEALVSTLE---PPYFVTELEPLEASVGDSVSLQCQVAGSPEITVSWY 6096
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K L+ P +T F +NVATL + + + +G+Y+C A N IG+ASS + E +
Sbjct: 6097 KGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQL 6156
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP F L ++ VG C + G+ PI+V+W +D +R N Q S+++N A L
Sbjct: 6157 PPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVSWYRDGVLLRDDENLQTSFVDNVATLK 6216
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
IL+ D +GQY+C A N +G S +A+L +E P F K +++ G S E
Sbjct: 6217 ILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIK-PVSIDIIAGESADFEC 6275
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
V G+QP+ + W K+N EI P N IT N L++ K GD+G YTC+ +ND G
Sbjct: 6276 HVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKD 6335
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVS-EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
+C++ + +KE PP F + L V+ +GE + L C + GS I++ W + E+ S
Sbjct: 6336 MCSAQLSVKE---PPKFVKKLEASKVAKQGESIHLECKISGSPEIKVSWFRNDSELHESW 6392
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ + SF + AVL + + D+GDY+C+A N G + + +T +
Sbjct: 6393 KYNMSFVDSVAVLTINEASAEDSGDYICEAHNGVGDASCSTALT---------------I 6437
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F +P I ++ + F ++ G P V W K + +Q+ + I K +A
Sbjct: 6438 KAPPVFTQKPSPIGALKGSDVVFQCEISGTPPFEVVWVKDR-KQVRSSKKFKITSKNFDA 6496
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHG 1700
L I + D G Y C A N+ G
Sbjct: 6497 SLHILNLEAADVGEYYCKATNEVG 6520
Score = 286 bits (732), Expect = 5e-77
Identities = 176/566 (31%), Positives = 266/566 (46%), Gaps = 1/566 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ + SA+ Q +AG+P I ++W K D L + F NNVATL VD+ SG
Sbjct: 5040 ITTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVHISFVNNVATLQIRSVDNGHSG 5099
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C+A+N G FL VQE P + + V T PV EC V+G+ + V
Sbjct: 5100 RYTCQAKNESGVERCYAFLLVQE---PAQIIEKAKSVDVTERDPVTLECVVAGTPELKVK 5156
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W KDG+ + SF +NVA+ I + +G+Y+ N GS+S A L + +
Sbjct: 5157 WLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGEYTFKVENDFGSSSCDAYLRVLDQ 5216
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F L +D V+G S EC V+G+ PI W KD +EI + Y++ EN+
Sbjct: 5217 NIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHENTVS 5276
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + ++ DT YTC N G +C+ L +KE PPSF K E + ++
Sbjct: 5277 LDVNNLELEDTANYTCRVSNVAGDAACSGILTVKE---PPSFLVK-PERQQAIPDSTVEF 5332
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+ + G+ P + W+K++VE+ C I + + L + G YTC+V+ND G
Sbjct: 5333 KAVLKGTPPFKIKWFKDDVELASGPKCFIGLEGSTSFLNLYSVDASKTGQYTCQVTNDVG 5392
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPV-TVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
S CT+++++ E PP F + L V G+ +L C + GS IR+ W + E+
Sbjct: 5393 SDSCTTTLLVTE---PPKFVKKLEATKIVKAGDSARLECKITGSPDIRVVWYRNEHELPA 5449
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
SD+ +F + AVL+ + D GD++C+A N AGS + +KV
Sbjct: 5450 SDKYRMAFIDSVAVLQMNYLGTEDTGDFICEAQNPAGSTSCSTKV--------------- 5494
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
V F S P + ++ + ++ G P V W K K RQL + I K
Sbjct: 5495 IVKEPPVFSSFPPVVETLKNAEVSIECELSGTPPFEVVWYKDK-RQLRSSKKYKIASKNF 5553
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHG 1700
A + I + D G Y C A N+ G
Sbjct: 5554 HASIHILNVDTLDIGEYHCKAQNEVG 5579
Score = 280 bits (715), Expect = 4e-75
Identities = 166/606 (27%), Positives = 293/606 (48%), Gaps = 1/606 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G +A+ Q L G+ I V+W K + ++ +M F NNVA+L + ++ G+Y+C+
Sbjct: 4483 GGTAAFQATLKGSLPITVTWLKDNEEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQ 4542
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A+N G L+V+E P + + + T G P + SG++ I+ WFKDG
Sbjct: 4543 AKNDAGIQRCFAVLSVKE---PATIIEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDG 4599
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ L G + S D V+ L I T++ +G+Y+ N +G +S A + + + PP
Sbjct: 4600 QELTLGQKYKISVTDTVSILKIISTEKRDSGEYTFEVQNDVGRSSCKASINVLDLIIPPS 4659
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L +D++ G S D EC V G+ PI + W KD++EI + Y+ S+ +N+A L I +
Sbjct: 4660 FTKKLKKMDSIKGSSIDLECIVAGSHPISIQWFKDDQEITASEKYKFSFHDNTAFLEISQ 4719
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
++ D+G YTC A N+ G + C+ L +KE PP F +K ++ + +L+ V
Sbjct: 4720 LEGSDSGTYTCSATNKAGHNQCSGHLTVKE---PPYFLEK-PQSQDVNPNTRVQLKALVG 4775
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+ P+++ W+K+N E+H A + + + +L++ A D+G Y C++SND G+A
Sbjct: 4776 GTAPMTIKWFKDNKELHSGAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGTATTK 4835
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTV-SEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+S+ +KE PP F + +PV V G+ C + G+ IR+ W G EI ++
Sbjct: 4836 ASLFVKE---PPQFIKKPSPVLVLRNGQSTTFECQITGTPEIRVSWYLDGNEITAVEKHG 4892
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF +G A + ++G YVC+A N AG+ + ++ V
Sbjct: 4893 ISFIDGLATFQISGARVENSGTYVCEAQNDAGTASCSIEL---------------KVKEP 4937
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F+ E + + VV+ + +V G V W + +++ + + + L
Sbjct: 4938 PTFIRELKPVEVVKDSDVELECEVMGTSPFQVTWLRNN-KEIRSSKKYTLTDRVSVFNLN 4996
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAGE 1817
I +D+G Y+C+ N+ G + + + E K ++ +LK + +
Sbjct: 4997 INRCDPSDTGDYQCIVSNEGGSCSCSARVSLKEPPSFIKKIENITTVLKSSATFQSTVAG 5056
Query: 1818 EEEIDI 1835
I I
Sbjct: 5057 SPPISI 5062
Score = 278 bits (712), Expect = 1e-74
Identities = 169/565 (29%), Positives = 274/565 (48%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++VT GD A+L+ +AGTPE+ WYK L + Y++ F+NNVA L F + +DSG
Sbjct: 4009 IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSG 4068
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y N VG S T TV ++ + P F++ LR+V V +C ++GS P+ VS
Sbjct: 4069 QYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVSGTCRLDCKIAGSLPMRVS 4128
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKDG+ + + +F++ A+L I + D S AG ++C ATN +GS S LI+ E
Sbjct: 4129 WFKDGKEVTSSDRYRIAFVEGTASLEISRVDMSDAGNFTCRATNSVGSKDCSGALIVQE- 4187
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F A D + G + + G+ P + W K ++E+ SGGN I+ +
Sbjct: 4188 --PPSFVTKPASKDILPGSAVFLKSTFQGSTPFTIRWFKGDKELVSGGNCYINKEALESS 4245
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + V D+G YTC N G C+A L +KE P +F ++L + +G++ +L
Sbjct: 4246 LELYSVKTTDSGTYTCKVSNVAGAVECSANLFVKE---PATFVERLELSQLLKKGDTTQL 4302
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+V G+ PI + W+ N+ EI ++ +++F + +L++ ++ D+G Y C+ N+AG
Sbjct: 4303 ACKVTGTPPIKITWFANDREIKESSKHKMSFVESTAVLRLTDIAVEDSGEYMCEAQNEAG 4362
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
S C+S +++KE P F + P+ V + + L V G+ P I W K ++
Sbjct: 4363 SDHCSSILIVKE---SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSG 4419
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + L+ AD G Y C+ +N GS T ++VT
Sbjct: 4420 RKYKTFIQDRLVSLQILKFVAADVGKYQCRVTNEVGSSTCSARVTLREPPT--------- 4470
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FV + +S + TA F A + G V W K ++ + I + + +
Sbjct: 4471 ------FVKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDN-EEITEDDNIRMTFENNV 4523
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHG 1700
A L + G Y C A N G
Sbjct: 4524 ASLYLSGIEVKHDGKYVCQAKNDAG 4548
Score = 275 bits (704), Expect = 8e-74
Identities = 173/581 (29%), Positives = 284/581 (48%), Gaps = 3/581 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++V L ++AGTP ++W+K +T LR YK ++ + +L + + D
Sbjct: 4384 PIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFIQDRLVSLQILKFVAADV 4443
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y CR N VG + S +T++E PP+F +++ G F+ + GS PI+V
Sbjct: 4444 GKYQCRVTNEVGSSTCSARVTLRE---PPTFVKKIESTSSLRGGTAAFQATLKGSLPITV 4500
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD + + NI+ +F +NVA+L + + G+Y C A N G A L + E
Sbjct: 4501 TWLKDNEEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCFAVLSVKE 4560
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P +D G+ A + +GT+ I W KD +E+ G Y+IS + +
Sbjct: 4561 ---PATIIEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGQKYKISVTDTVS 4617
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I+ +K D+G+YT N+VG+ SC A +N+ + +IPPSFTKKL + ++ +G+S
Sbjct: 4618 ILKIISTEKRDSGEYTFEVQNDVGRSSCKASINVLDLIIPPSFTKKLKK-MDSIKGSSID 4676
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE VAGS PIS+ W+K++ EI + + +F +N L++ + D+G YTC +N A
Sbjct: 4677 LECIVAGSHPISIQWFKDDQEITASEKYKFSFHDNTAFLEISQLEGSDSGTYTCSATNKA 4736
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G C+ + +KE PP F + V+ +QL V G+ P+ I+W K +E+
Sbjct: 4737 GHNQCSGHLTVKE---PPYFLEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHS 4793
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + +LE AD+G Y+C+ SN G+ T+K+ +
Sbjct: 4794 GAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGTATTKASL--------------- 4838
Query: 1443 XVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDPIPNVKW--TKGKWRQLNQGGRIFIHQ 1613
V F+ +P + V+ + TF ++ G P V W + + + G FI
Sbjct: 4839 FVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPEIRVSWYLDGNEITAVEKHGISFI-- 4896
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A +I +SG Y C A N G ++ L+V E
Sbjct: 4897 -DGLATFQISGARVENSGTYVCEAQNDAGTASCSIELKVKE 4936
Score = 273 bits (698), Expect = 4e-73
Identities = 171/579 (29%), Positives = 279/579 (48%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+V L+C++ GT V+W + + ++R + Y + R +V L N+ D +D+
Sbjct: 4946 PVEVVKDSDVELECEVMGTSPFQVTWLRNNKEIRSSKKYTLTDRVSVFNLNINRCDPSDT 5005
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y C N G S S ++++E PPSF +++ ++ + F+ V+GS PIS+
Sbjct: 5006 GDYQCIVSNEGGSCSCSARVSLKE---PPSFIKKIENITTVLKSSATFQSTVAGSPPISI 5062
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD + L + N+ SF++NVATL I D +G+Y+C A N G A L++ E
Sbjct: 5063 TWLKDDQILDEDDNVHISFVNNVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQE 5122
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P VD + EC V GT +KV W KD ++I + +S+ N A
Sbjct: 5123 ---PAQIIEKAKSVDVTERDPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVA 5179
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
I V K D+G+YT N+ G SC A L + ++ IPPSFTKKL++ +++ G+S
Sbjct: 5180 SFRIQSVMKQDSGEYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTK-MDKVLGSSIH 5238
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
+E +V+GS PIS W+K+ EI +A + N + L V + D YTC+VSN A
Sbjct: 5239 MECKVSGSLPISAQWFKDGKEISTSAKYRLVCHENTVSLDVNNLELEDTANYTCRVSNVA 5298
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G A C+ + +KEP V + + S EF + ++G+ P +I+W K E+
Sbjct: 5299 GDAACSGILTVKEPPSFLVKPERQQAIPDSTVEFKAV---LKGTPPFKIKWFKDDVELAS 5355
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+C T+ L V + G Y C+ +N GSD+ + +
Sbjct: 5356 GPKCFIGLEGSTSFLNLYSVDASKTGQYTCQVTNDVGSDSCTTTL--------------- 5400
Query: 1443 XVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V FV + ++ ++V+ +A K+ G P V W + + +L + +
Sbjct: 5401 LVTEPPKFVKKLEATKIVKAGDSARLECKITGSPDIRVVWYRNE-HELPASDKYRMAFID 5459
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L++ D+G + C A N G + + V E
Sbjct: 5460 SVAVLQMNYLGTEDTGDFICEAQNPAGSTSCSTKVIVKE 5498
Score = 273 bits (698), Expect = 4e-73
Identities = 178/577 (30%), Positives = 271/577 (46%), Gaps = 2/577 (0%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWY--KGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VGD+ L+ + G I V W KGD +R + ++ F +NVATL +++DSG+Y
Sbjct: 6547 VGDAVELRAVVEGFQPISVVWLKDKGDV-IRESENTRISFVDNVATLQLGSPEASDSGKY 6605
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
+C+ +N G S LTV E P + + T G EC V+G+ +S WF
Sbjct: 6606 VCQIKNDAGMRECSAILTVLE---PARIIEKPEPMTVTTGNAFALECVVTGTPELSAKWF 6662
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDGR + +F++ VA+L I + S G YS N +G ++ + + +++
Sbjct: 6663 KDGREIAADSKHHITFVNKVASLKIPCAEMSDKGLYSFEVKNSVGKSTCTVSVHVSDRIV 6722
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
P F L ++A+VG S EC V+G+ PI V W +D EI SG Q S+ EN L
Sbjct: 6723 APSFIRKLKDINAIVGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLN 6782
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
+ ++ DTG YTC A N G D C+A L I+E PPSF ++ ++VE G S
Sbjct: 6783 LSFLEPSDTGTYTCVAANVAGSDECSAVLTIQE---PPSF-EQTPDSVEVLPGTSLTFTS 6838
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
+ G+ P V W+K + E+ +C I+ ++ L++ + +G Y+C V+NDAGSA
Sbjct: 6839 VIRGTPPFKVKWFKGSRELVSGESCSISLEDFVTELELFEVEPLQSGDYSCLVTNDAGSA 6898
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
CT+ + +KE P F + L +V G + L G+ PI + W+K + S
Sbjct: 6899 SCTAHLFVKE---PATFVKRLADFSVETGSPIVLEATFTGTPPISVSWMKNEFALTQSQN 6955
Query: 1272 CSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVD 1451
CS + + +LE D T D Y C N AG D + V+
Sbjct: 6956 CSITMTEKSTILEILDSTIEDYAQYSCLIENEAGQDICDAVVSVLEPP------------ 7003
Query: 1452 GKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAK 1631
+F+ + + V T KV G P + W K + +L + K + A
Sbjct: 7004 ---YFIEPLEHVEAVIGEPITLQCKVDGTPEIRISWYK-EHTKLRSAPAYKMQFKNNVAS 7059
Query: 1632 LEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
L I +D G Y C A N G + S+ L + ERK
Sbjct: 7060 LVINKVDHSDVGEYTCKAENIVGAVASSSVLVIKERK 7096
Score = 267 bits (683), Expect = 2e-71
Identities = 173/579 (29%), Positives = 269/579 (46%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+ + L+ Q+ ++ ++W K KL P YK++F + +A+L DS
Sbjct: 3635 PVQSAINKKIHLEGQVDEDRKVTITWSKNGQKLPPGKDYKIYFEDKIASLEIPLAKLKDS 3694
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-GLPVVFECAVSGSEPIS 359
G Y+C A N G S+S +T++E PPSF +++ + G C + GS I
Sbjct: 3695 GTYVCTASNEAGSSSTSATVTIRE---PPSFVKKVDPSYLMLPGESARLHCRLKGSPVIQ 3751
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V+WFK+ + L + I+ SF+++ A L+I +G YSC A N +GS S SA +++
Sbjct: 3752 VTWFKNNKELTESNTIRMSFVNSEAVLDITDVKVEDSGTYSCEAVNDVGSDSCSAEIVVK 3811
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E PP F L P D V G +A +C + GT P +++W KD ++IRS Y++ +++
Sbjct: 3812 E---PPSFIKTLEPADIVRGTNALLQCEIAGTGPFEISWFKDKKQIRSSKKYRLFSQKST 3868
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I + D G Y C NEVGK C A +KE PP+F KK+ + G +
Sbjct: 3869 VSLEIFSFNSADVGDYECVVANEVGKCGCVATHLLKE---PPTFVKKVDD-FTALAGQTV 3924
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L+ V GS+PISV W K I +++F N +L + + YTC N+
Sbjct: 3925 TLQAAVRGSEPISVTWMKGQEIIKEDGKIKMSFANGVAVLIIPDVQISFGDKYTCLAENE 3984
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS +++KEP K + + V+ G+ L V G+ ++ +W K GR +
Sbjct: 3985 AGSQTSVGELIVKEPAK---IIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLV 4041
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
S + SF N A L+F D+G Y + SN GS + ++ T
Sbjct: 4042 ASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDR--------- 4092
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
D FF +++ V T K+ G V W K +++ R I
Sbjct: 4093 ---DIAPFFTKPLRNVDSVVSGTCRLDCKIAGSLPMRVSWFK-DGKEVTSSDRYRIAFVE 4148
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A LEI +D+G + C A N G + + L V E
Sbjct: 4149 GTASLEISRVDMSDAGNFTCRATNSVGSKDCSGALIVQE 4187
Score = 259 bits (662), Expect = 6e-69
Identities = 172/581 (29%), Positives = 257/581 (44%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++V +G A C++ P + W+K ++ + + N V TL + D
Sbjct: 3447 PLEVALGHLAKFTCEIHSAPNVRFQWFKAGREIYESDKCSIRSANYVTTLEILRTQVVDC 3506
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+A N G VS + LTV E PP+F + + V VG F C V+G+ I
Sbjct: 3507 GEYTCKASNEYGSVSCTATLTVTEA-YPPTFFSRPKSVTTFVGKAAKFLCTVTGTPVIET 3565
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W KDG L P + S +DN L + G YSC A+N G+ + A L + +
Sbjct: 3566 IWQKDGMALSPSPTCKISDVDNKHILELSNLTVHDKGVYSCKASNKFGADTCQAELDIID 3625
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L PV + + + E V + + + W+K+ +++ G +Y+I + + A
Sbjct: 3626 ---KPHFIKELEPVQSAINKKIHLEGQVDEDRKVTITWSKNGQKLPPGKDYKIYFEDKIA 3682
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I D+G Y C A NE G S +A + I+E PPSF KK+ + G S R
Sbjct: 3683 SLEIPLAKLKDSGTYVCTASNEAGSSSTSATVTIRE---PPSFVKKVDPSYLMLPGESAR 3739
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L R+ GS I V W+KNN E+ + ++F N+ +L + + D+G Y+C+ ND
Sbjct: 3740 LHCRLKGSPVIQVTWFKNNKELTESNTIRMSFVNSEAVLDITDVKVEDSGTYSCEAVNDV 3799
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GS C++ IV+KE PP F + L P + G L C + G+ P I W K ++I+
Sbjct: 3800 GSDSCSAEIVVKE---PPSFIKTLEPADIVRGTNALLQCEIAGTGPFEISWFKDKKQIRS 3856
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + T LE AD GDY C +N G
Sbjct: 3857 SKKYRLFSQKSTVSLEIFSFNSADVGDYECVVANEVGK---------------CGCVATH 3901
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+ FV + + T T A V G +V W KG+ + + G+I +
Sbjct: 3902 LLKEPPTFVKKVDDFTALAGQTVTLQAAVRGSEPISVTWMKGQ-EIIKEDGKIKMSFANG 3960
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
A L I D + Y C+A N+ G S L V E K
Sbjct: 3961 VAVLIIPDVQISFGDKYTCLAENEAGSQTSVGELIVKEPAK 4001
Score = 220 bits (560), Expect = 4e-57
Identities = 159/600 (26%), Positives = 255/600 (42%), Gaps = 22/600 (3%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ V G A ++G P+ +SWYK + L K TL+ + D+
Sbjct: 3234 PITVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDA 3293
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKL----------PPSFSRQLRDVQETVGLPVVFEC 332
Y C A N G ++S L+V+ ++ PP+ L+D + G P F+C
Sbjct: 3294 AVYTCEARNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIVSPLQDAVTSEGRPAHFQC 3353
Query: 333 AVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSA 512
VSG++ + VSW+ + +K + + ++ L + + G Y+ A+N +G
Sbjct: 3354 RVSGTD-LKVSWYSKDKKIKPSRFFKMTQFEDTYQLEVAEAFPEDEGIYTFVASNAVGQV 3412
Query: 513 SSSARLILT------------EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAW 656
SS+A L L E + P + P++ +G A F C + ++ W
Sbjct: 3413 SSTATLRLEAPEAMLHEQIEMEMKAAPVIRRRIEPLEVALGHLAKFTCEIHSAPNVRFQW 3472
Query: 657 AKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERL 836
K REI I L IL+ D G+YTC A NE G SCTA L + E
Sbjct: 3473 FKAGREIYESDKCSIRSANYVTTLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAY 3532
Query: 837 IPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALL 1016
P F++ S T G + + V G+ I W K+ + + P+ C+I+ +N +
Sbjct: 3533 PPTFFSRPKSVTT--FVGKAAKFLCTVTGTPVIETIWQKDGMALSPSPTCKISDVDNKHI 3590
Query: 1017 LQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLS 1196
L++ ++ D G+Y+CK SN G+ C + + I + P F + L PV + + + L
Sbjct: 3591 LELSNLTVHDKGVYSCKASNKFGADTCQAELDIIDK---PHFIKELEPVQSAINKKIHLE 3647
Query: 1197 CHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGS 1376
V + I W K G+++ P F + A LE D+G YVC ASN AGS
Sbjct: 3648 GQVDEDRKVTITWSKNGQKLPPGKDYKIYFEDKIASLEIPLAKLKDSGTYVCTASNEAGS 3707
Query: 1377 DTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVK 1556
++ + VT + F S ++ +A ++ G P+ V
Sbjct: 3708 SSTSATVTIR--------------EPPSFVKKVDPSYLMLPGESARLHCRLKGSPVIQVT 3753
Query: 1557 WTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
W K ++L + I + EA L+I D DSG Y C A N G + + V E
Sbjct: 3754 WFKNN-KELTESNTIRMSFVNSEAVLDITDVKVEDSGTYSCEAVNDVGSDSCSAEIVVKE 3812
Score = 181 bits (459), Expect = 2e-45
Identities = 156/636 (24%), Positives = 272/636 (42%), Gaps = 26/636 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+KV A +C+++ P+I V W K +L+ K+ V L+ +D+G
Sbjct: 3054 IKVLEKKRAMFECEVS-EPDITVQWMKDGQELQLVDRIKIQKEKYVHRLLIPSTRMSDAG 3112
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y A G +SS+ S R+++ +++ + V FE + +
Sbjct: 3113 KYTVVAG---GNMSSANLFVEGRDVRIRSIKREVQVIEKQRAV-VEFEV---NEDDVDAH 3165
Query: 366 WFKDGRPLKDGPNIQTSFL--DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
W+KDG + + ++ + + I +T S AG+Y+ A G SS L +
Sbjct: 3166 WYKDGIEINFQVQERHQYVVERRIHRMFISETRHSDAGEYTFVA----GRNRSSVTLYVN 3221
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
PP L P+ G+ A F ++G K++W K+ + + +G ++ +L +
Sbjct: 3222 -APEPPQILQELQPITVQSGKPARFCAVISGRPQPKISWYKEEQLLSTG--FKCKFLHDG 3278
Query: 720 AHLTILKVDK--GDTGQYTCYAVNEVGKDSCTAQLNIKERLI----------PPSFTKKL 863
T+L ++ D YTC A N+ G + +A L+++ + PP+ L
Sbjct: 3279 QEYTLLLIEAFPEDAAVYTCEARNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIVSPL 3338
Query: 864 SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMG 1043
+ V +EG + RV+G+ + V+WY + +I P+ ++T + L+V +A
Sbjct: 3339 QDAVT-SEGRPAHFQCRVSGTD-LKVSWYSKDKKIKPSRFFKMTQFEDTYQLEVAEAFPE 3396
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEP------------KKPPVFDQHLTPVTVSEGEFL 1187
D G+YT SN G T+++ ++ P K PV + + P+ V+ G
Sbjct: 3397 DEGIYTFVASNAVGQVSSTATLRLEAPEAMLHEQIEMEMKAAPVIRRRIEPLEVALGHLA 3456
Query: 1188 QLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNV 1367
+ +C + + +R QW KAGREI SD+CS AN LE D G+Y CKASN
Sbjct: 3457 KFTCEIHSAPNVRFQWFKAGREIYESDKCSIRSANYVTTLEILRTQVVDCGEYTCKASNE 3516
Query: 1368 AGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIP 1547
GS + + +T F S P+S+ A F+ V G P+
Sbjct: 3517 YGSVSCTATLTVTEAYPPT-------------FFSRPKSVTTFVGKAAKFLCTVTGTPVI 3563
Query: 1548 NVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
W K L+ I ++ LE+ + T D G+Y C A NK G L
Sbjct: 3564 ETIWQK-DGMALSPSPTCKISDVDNKHILELSNLTVHDKGVYSCKASNKFGADTCQAELD 3622
Query: 1728 VNERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEIDI 1835
+ ++ K +++ + K L+ E+ ++ I
Sbjct: 3623 IIDKPHFIKELEPVQSAINKKIHLEGQVDEDRKVTI 3658
Score = 129 bits (325), Expect = 7e-30
Identities = 128/463 (27%), Positives = 202/463 (43%), Gaps = 4/463 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKL-RPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
G A + ++ G P+ WYK K+ R Y +NV LV V + DS +
Sbjct: 2079 GSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMV 2138
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRD-VQETVGLPVVFECAVSGSEP-ISVSWF 371
+A N GE SS FL VQ ++L +F+++L+D V + FEC SEP + V W+
Sbjct: 2139 KAINIAGETSSHAFLLVQAKQL-ITFTQELQDVVAKEKDTMATFECET--SEPFVKVKWY 2195
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDG + G + V L++ D S A YSC + ++A+LI+ EG
Sbjct: 2196 KDGVEIHTGDKYRMHSDRKVHFLSVLMIDTSDAEDYSCVLVED-ENVKTTAKLIV-EGAV 2253
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
F L ++ S + EC +T + I+ W E++S G Y I+ +LT
Sbjct: 2254 VEFVK-ELQDIEVPESFSGELECIIT-PENIEGKWYHKGVELKSNGKYTITSRRGRQNLT 2311
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
+ V K D G+Y+ + V+ GK + T +L +K R P + + LS+ + EG+ +LE
Sbjct: 2312 VKDVTKEDQGEYS-FVVD--GKKT-TCKLKMKPR--PIAILQGLSDQ-KVCEGDIVQLEV 2364
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
+V+ + + W K+ E+ P I + +L ++ + DAG Y+ + + S
Sbjct: 2365 KVS-LENVEGVWMKDGEEVQPGDRVHIVIDKQSHMLLIEDMTKEDAGHYSFTIPSLGLST 2423
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
S+ + P L V V EG L C V + ++W +IKP DR
Sbjct: 2424 HGRVSVYSVDVITP------LKDVNVLEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR 2477
Query: 1272 CSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGS-DTSKSKV 1397
L +D G Y V S D S K+
Sbjct: 2478 VHAIVKGTKQRLVINRTHASDEGPYKLVVGRVETSCDLSVEKI 2520
Score = 127 bits (318), Expect = 5e-29
Identities = 155/637 (24%), Positives = 259/637 (40%), Gaps = 28/637 (4%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV + G+ L C + G+ I + W K +++P+ F N A L V D+
Sbjct: 8337 PVTASEGEFVQLSCHVWGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLELKDVTKADA 8396
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLP-PSFSRQLRD-----VQETVGLPVVFECAVS- 341
G+Y+C+A N G +S + +T++++ P+ + D V E + VV + +
Sbjct: 8397 GDYVCKASNVAGSDTSKSKVTIKDKPAAVPAAKKAAVDGKLFFVSEPQSIRVVEKTTATF 8456
Query: 342 ----GSEPI-SVSWFKDG-RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPI 503
G +PI +V W K R L G I + A L I T ++ +G Y C A N
Sbjct: 8457 IAKVGGDPIPNVKWTKGKWRQLNQGGRILIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKH 8516
Query: 504 GSASSSARLILTEGRNPPFFDIPLAPV---DAVVGESADFECHVTGTQPIKVAWAKD-NR 671
G S+ L + E + + L + V+ + A E + + +K K+ +
Sbjct: 8517 GEIESNVNLQVDERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEIDIMELLKNVDPKEYEK 8576
Query: 672 EIRSGGNYQISYLENSAHLTILKVDKGD-TGQYTCYAVNEVGKDSCTAQ---LNIKERLI 839
R G L + L LK +G+ T + + + KD + I++RL
Sbjct: 8577 YARMYGITDFRGLLQAFEL--LKQTEGEETHRLEIEEIEKSEKDEKEFEELVSFIQQRLS 8634
Query: 840 ---PPSFTKKL-SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNN 1007
P + K + ++TV + F ++ ++ + I ++WYK ++ P+ EI+ +
Sbjct: 8635 QTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPE-IKLSWYKGTEKLEPSDKFEISIDGD 8693
Query: 1008 ALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFL 1187
L+VK + D G Y SA T VI+ P +++HL VT+ EG+
Sbjct: 8694 RHTLRVKNCQLKDQGNYRLVCGPHIASAKLT---VIE-----PAWERHLQDVTLKEGQTC 8745
Query: 1188 QLSCHVRGSEP-IRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASN 1364
++C S P +R +W + GR +KP R + L DV D G Y CK +
Sbjct: 8746 TMTCQF--SVPNVRSEWFRNGRILKPQGRYKTEVEHKVHKLTIADVRAEDQGRYTCKHED 8803
Query: 1365 VAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPI 1544
+ S + + + F Q+I V E +ATF +V D
Sbjct: 8804 LETSAELRIEAE------------------PIQFTKRIQNIVVSEHQSATFECEVSFDD- 8844
Query: 1545 PNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVA-FNKHGEIESNVN 1721
V W KG +L + + G + I + T D G+Y +A GE S
Sbjct: 8845 AIVTWYKGP-TELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAE 8903
Query: 1722 LQVNERK-KQEKIEGDLRAMLKKTPVLKKGAGEEEEI 1829
L + ++ K E D+ P + A EEI
Sbjct: 8904 LYLTTKEIKLEMKPPDIPDSRVPIPTMPIRAIPPEEI 8940
Score = 122 bits (305), Expect = 2e-27
Identities = 150/600 (25%), Positives = 239/600 (39%), Gaps = 14/600 (2%)
Frame = +3
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-------GLPVVFECAVSGSEPISV 362
+ ++ E T T + K+ S S + + E + G F V G
Sbjct: 2037 KKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC 2096
Query: 363 SWFKDGRPLKDGPNIQTSFL-DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
W+K+G ++ I + DNV L I + A N G SS A +L
Sbjct: 2097 EWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHA-FLLV 2155
Query: 540 EGRNPPFFDIPLAPVDAVVGES-ADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
+ + F L V A ++ A FEC T +KV W KD EI +G Y++
Sbjct: 2156 QAKQLITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGVEIHTGDKYRMHSDRK 2214
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
L++L +D D Y+C V + + TA+L ++ ++ F K+L + +E E S
Sbjct: 2215 VHFLSVLMIDTSDAEDYSCVLVEDENVKT-TAKLIVEGAVV--EFVKELQD-IEVPESFS 2270
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
LE + + I WY VE+ IT + L VK + D G Y+ V
Sbjct: 2271 GELE-CIITPENIEGKWYHKGVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVV-- 2327
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
D C +K +P Q L+ V EG+ +QL V E + W+K G E+
Sbjct: 2328 DGKKTTCK----LKMKPRPIAILQGLSDQKVCEGDIVQLEVKV-SLENVEGVWMKDGEEV 2382
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
+P DR + +L +D+TK DAG Y ++ S + V
Sbjct: 2383 QPGDRVHIVIDKQSHMLLIEDMTKEDAGHYSFTIPSLGLSTHGRVSV------------- 2429
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
VD ++ + + V+E T A KV + +VKW Q+ R+ K
Sbjct: 2430 -YSVD----VITPLKDVNVLEGTKAVLECKVSVPDVTSVKWYLND-EQIKPDDRVHAIVK 2483
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPV 1796
G + +L I T +D G Y+ V G +E++ +L V + K + DL + V
Sbjct: 2484 GTKQRLVINRTHASDEGPYKLVV----GRVETSCDLSVEKIKIIRGLR-DLTCTETQNVV 2538
Query: 1797 LKKGAGEEEEIDIMELLKNVDPKEYEKY-----ARMYGITDFRGLLQAFEMLKQSQEEET 1961
L+ ID++ K+ + K KY ++Y +T M+K + E T
Sbjct: 2539 LEVEL-SHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLT-------VLNMMKDDEGEYT 2590
Score = 112 bits (280), Expect = 1e-24
Identities = 112/507 (22%), Positives = 184/507 (36%), Gaps = 48/507 (9%)
Frame = +3
Query: 24 DSASLQCQLAGTPEIG--VSWYKGDTKLRPTATYKMHFR-NNVATLVFNQVDSNDSGEYI 194
D A L C + + V+WYK +L+ ++ H+ + L + +D GEY+
Sbjct: 32757 DIAKLTCVVESSALCAKEVTWYKDGRRLKENGHFQFHYSADGTYELKILNLAESDRGEYV 32816
Query: 195 CRAENSVGEVSSS------TFLTVQEQ---------------------------KLPPSF 275
C G ++ F ++ EQ K P
Sbjct: 32817 CEVSGEGGTSKTNFQFVGQAFKSIHEQVSSISETKKAKAAPKTAEPTETKKTEPKAPAPI 32876
Query: 276 SRQ------LRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVAT 437
S + L+D + F V+G +V W KDG+ + G + S
Sbjct: 32877 STKPVIVTGLQDTTVSSDSVAKFAVKVTGEPQPTVIWTKDGKAISQGGKYKLSEDKGAFF 32936
Query: 438 LNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGE----- 602
L I +TD S +G Y+CT TN GS SSS +L + + + + +
Sbjct: 32937 LEIHKTDTSDSGLYTCTITNSAGSVSSSCKLTIKVVEDTEIQKVSAQKTSEITSQKKASV 32996
Query: 603 SADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAV 782
+ ++ IK + K + ++ E S L KV K + V
Sbjct: 32997 QEEISKKALISEEIKTSEVKSHEKLALKE-------EASTVLISEKVKKSEAASLEKSVV 33049
Query: 783 NEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNV 962
+E T E + + K S + T G L+ +AG+ V W N V
Sbjct: 33050 HE----EITKTSQASEEIRTHAEIKAFSTQMSITAGQKVTLKANIAGA--TDVKWVLNGV 33103
Query: 963 EIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVI-KEPKKPPV 1139
E+ + + L +++A D G+ TC G C + + KE P
Sbjct: 33104 ELSNSDEYRYGISGSDQTLTIRQAGHKDEGILTCIGKTSQGIIKCQYDLTLSKELSDAPA 33163
Query: 1140 FDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKD 1319
F V+EG+ + SC + G I+W K I S S S + LE ++
Sbjct: 33164 FISQPRSQNVNEGQNVLFSCEISGEPSPEIEWFKNNLPISISSNISVSRSRNVYSLEIRN 33223
Query: 1320 VTKADAGDYVCKASNVAGSDTSKSKVT 1400
+ +D+G Y KA N G ++ + +T
Sbjct: 33224 ASVSDSGKYTIKAKNFHGQCSATASLT 33250
Score = 111 bits (277), Expect = 3e-24
Identities = 114/502 (22%), Positives = 197/502 (39%), Gaps = 45/502 (8%)
Frame = +3
Query: 360 VSWFKDGRPLKDGPNIQTSF-LDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI- 533
V+W+KDGR LK+ + Q + D L I S G+Y C + G++ ++ + +
Sbjct: 32775 VTWYKDGRRLKENGHFQFHYSADGTYELKILNLAESDRGEYVCEVSGEGGTSKTNFQFVG 32834
Query: 534 --------------------------------LTEGRNPPFFDIPLAPV------DAVVG 599
TE + P I PV D V
Sbjct: 32835 QAFKSIHEQVSSISETKKAKAAPKTAEPTETKKTEPKAPA--PISTKPVIVTGLQDTTVS 32892
Query: 600 ES--ADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTC 773
A F VTG V W KD + I GG Y++S + + L I K D D+G YTC
Sbjct: 32893 SDSVAKFAVKVTGEPQPTVIWTKDGKAISQGGKYKLSEDKGAFFLEIHKTDTSDSGLYTC 32952
Query: 774 YAVNEVGKDSCTAQLNIKERLIPPSFTKKLS--ETVEETEGNSFRLEGRVAGSQPISVAW 947
N G S + +L IK ++ + +K+S +T E T ++ ++ IS
Sbjct: 32953 TITNSAGSVSSSCKLTIK--VVEDTEIQKVSAQKTSEITSQKKASVQEEISKKALISEEI 33010
Query: 948 YKNNVEIHPTANCEITFKNNA-LLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEP 1124
+ V+ H ++ K A +L +K +A V ++ + +S I+
Sbjct: 33011 KTSEVKSHE----KLALKEEASTVLISEKVKKSEAASLEKSVVHEEITKTSQASEEIRTH 33066
Query: 1125 KKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAV 1304
+ F T ++++ G+ + L ++ G+ ++ W+ G E+ SD + +
Sbjct: 33067 AEIKAFS---TQMSITAGQKVTLKANIAGATDVK--WVLNGVELSNSDEYRYGISGSDQT 33121
Query: 1305 LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS 1484
L + D G C G + +T + F+S+P+S
Sbjct: 33122 LTIRQAGHKDEGILTCIGKTSQGIIKCQYDLT-----------LSKELSDAPAFISQPRS 33170
Query: 1485 IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDS 1664
V E F ++ G+P P ++W K ++ I + + + LEIR+ + +DS
Sbjct: 33171 QNVNEGQNVLFSCEISGEPSPEIEWFKNN-LPISISSNISVSRSRNVYSLEIRNASVSDS 33229
Query: 1665 GLYRCVAFNKHGEIESNVNLQV 1730
G Y A N HG+ + +L V
Sbjct: 33230 GKYTIKAKNFHGQCSATASLTV 33251
Score = 110 bits (276), Expect = 4e-24
Identities = 136/560 (24%), Positives = 225/560 (40%), Gaps = 4/560 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+V ++A + +++ +I +W L T ++ L+ + + +G
Sbjct: 12133 VEVMETETARFETEIS-EDDIHANWKLKGEALLQTPECEIKEEGKTHFLILHNCRLDQTG 12191
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+A N V SS L V+ + + R L+D+ T G F+C +S E I V
Sbjct: 12192 GVDFQAAN----VKSSAHLRVKPRVI--GLLRPLKDITVTAGETATFDCELS-YEDIPVE 12244
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+ G+ L+ + V TL + AG+ A + + A+L + E
Sbjct: 12245 WYLRGKKLEPSDKVVMRSEGRVHTLTLRDVKLEDAGEVQLVAKD----FKTQAKLFVKEP 12300
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P F PL +A EC V+ + KV W K+ EI Y+I
Sbjct: 12301 --PVEFTKPLEDQTVEEEATAVLECEVS-RENAKVKWFKNGTEILKSKKYEIVADGRVRK 12357
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPP--SFTKKLSET-VEETEGNS 896
L I D YTC A + K SC LN+ +PP F + L++ V+E E
Sbjct: 12358 LIIHGCTPEDIKTYTCDAKDF--KTSCN--LNV----VPPHVEFLRPLTDLRVKEKEMAR 12409
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
F E + V W+K+ EI +I K +L + K + D Y+C+V
Sbjct: 12410 FECE---ISRENAKVHWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRT 12466
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEP-IRIQWLKAGRE 1253
S + T V++E VF ++L + VSE + ++L C V S+P + W K E
Sbjct: 12467 ARTSGMLT---VLEE---EAVFTKNLANIEVSETDTVKLVCEV--SKPGAEVTWYKGDEE 12518
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
I + R +L ++ DAG+Y C+ S + KV
Sbjct: 12519 IIETGRYEILTDGRKRILIIQNAHLEDAGNYNCRLP----SSRTDGKVKVHELAAE---- 12570
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
F+S+PQ++ ++E A F+ + + V+W + + L G + +
Sbjct: 12571 ----------FISKPQNLEILEGEKAEFVCSISKENF-EVQWKRDD-KTLESGDKYDVIA 12618
Query: 1614 KGDEAKLEIRDTTKTDSGLY 1673
G + L ++D T D G Y
Sbjct: 12619 DGKKRVLVVKDATLQDMGTY 12638
Score = 110 bits (274), Expect = 6e-24
Identities = 147/679 (21%), Positives = 251/679 (36%), Gaps = 54/679 (7%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSN--DS 182
+V G + + P V WY +L+ ++ K+H+ N L +D + DS
Sbjct: 32408 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTLEILDCHIDDS 32465
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y N GE S L V +++ Q RD Q +P ++ +E +V
Sbjct: 32466 GTYRAVCTNYKGEASDYATLDVTGGDYT-TYASQRRDEQ----VPRSVFPELTRTEAYAV 32520
Query: 363 SWFKDGRPLKDGPNIQ---TSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL- 530
S FK ++ +++ + + +L+ ++ S + + + S+ ++
Sbjct: 32521 SSFKKTSEMEASSSVREMKSLMTETRESLSSYEHHASAEMKSAAIEEKSLEEKSTHRKIK 32580
Query: 531 ------ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
ILT+ R+ ++ GESA F C G V W + + I +
Sbjct: 32581 TTLAARILTKPRSITVYE----------GESARFSCDTDGEPVPTVTWLRGGQVISTSAR 32630
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLI------PPSFT 854
+Q++ + + I V D G Y+ N G+ L +++ + P
Sbjct: 32631 HQVTTSKYKSTFEISSVQASDEGNYSVVVENSDGRQEAQFTLTVQKARVTEKAVTSPPRV 32690
Query: 855 KKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKA 1034
K V+ EG + RV +P++ HP A
Sbjct: 32691 KSPEPRVKSPEG--AKSPKRVKSPEPVTP---------HPKA------------------ 32721
Query: 1035 SMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGS 1214
V T + K PP Q L + + +L+C V S
Sbjct: 32722 -----------VPPTETKPTPTEKVQQKPVAAPPKIIQSLK--AEASKDIAKLTCVVESS 32768
Query: 1215 E--PIRIQWLKAGREIKPSDRCSFSF-ANGTAVLEFKDVTKADAGDYVCKASNVAG---- 1373
+ W K GR +K + F + A+GT L+ ++ ++D G+YVC+ S G
Sbjct: 32769 ALCAKEVTWYKDGRRLKENGHFQFHYSADGTYELKILNLAESDRGEYVCEVSGEGGTSKT 32828
Query: 1374 -------------------SDTSKS----KVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS 1484
S+T K+ K + K V+ Q
Sbjct: 32829 NFQFVGQAFKSIHEQVSSISETKKAKAAPKTAEPTETKKTEPKAPAPISTKPVIVTGLQD 32888
Query: 1485 IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDS 1664
V + A F KV G+P P V WTK + ++QGG+ + + LEI T +DS
Sbjct: 32889 TTVSSDSVAKFAVKVTGEPQPTVIWTK-DGKAISQGGKYKLSEDKGAFFLEIHKTDTSDS 32947
Query: 1665 GLYRCVAFNKHGEIESN--VNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEID-- 1832
GLY C N G + S+ + ++V E + +K+ + + +K A +EEI
Sbjct: 32948 GLYTCTITNSAGSVSSSCKLTIKVVEDTEIQKVSAQKTSEITS----QKKASVQEEISKK 33003
Query: 1833 --IMELLKNVDPKEYEKYA 1883
I E +K + K +EK A
Sbjct: 33004 ALISEEIKTSEVKSHEKLA 33022
Score = 109 bits (273), Expect = 8e-24
Identities = 71/220 (32%), Positives = 111/220 (50%), Gaps = 3/220 (1%)
Frame = +3
Query: 267 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDG--PNIQTSFLDNVATL 440
P+F++ L+ V G FE +SG VSWF+DG+ + P +Q SF D A L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 441 NIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFEC 620
I ++ +G+YS ATN G A+S+A L++T PP F L + G +
Sbjct: 66 TIPAVTKANSGRYSLRATNGSGQATSTAELLVTAETAPPNFTQRLQSMTVRQGSQVRLQV 125
Query: 621 HVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKD 800
VTG V + +D EI+S ++QIS L I + D+G Y+ A N VG+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQISQEGELYSLLIAEAYPEDSGTYSVNATNSVGRA 185
Query: 801 SCTAQLNIK-ERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+ TA+L ++ E ++P TK + T + +E R+E ++
Sbjct: 186 TSTAELLVQGEEVVPAKRTKTIVSTAQISETRQTRIEKKI 225
Score = 109 bits (273), Expect = 8e-24
Identities = 136/592 (22%), Positives = 224/592 (37%), Gaps = 4/592 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++V+ D+ L C+++ P V+WYKGD ++ T Y++ L+ D+G
Sbjct: 12489 IEVSETDTVKLVCEVS-KPGAEVTWYKGDEEIIETGRYEILTDGRKRILIIQNAHLEDAG 12547
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y CR SS T V+ +L F + ++++ G F C++S E V
Sbjct: 12548 NYNCRLP------SSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSIS-KENFEVQ 12600
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W +D + L+ G L + G Y +G+A ++A L + E
Sbjct: 12601 WKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTVIEK 12656
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
+PL + F C V T+ K W +++ I Y I +
Sbjct: 12657 LR---IIVPLKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNDEAIFDSSKYIILQKDLVYT 12712
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKD-SCTAQLNIKE---RLIPPSFTKKLSETVEETEGN 893
L I D Y N G++ A L ++E R+I P K ET+E+
Sbjct: 12713 LRIRNAQLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIIEP---LKDIETMEKKSVT 12769
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
+ R+ +++ W KN E+ L +K D G Y
Sbjct: 12770 FWCKVNRL----NVTLKWTKNGEEVAFDNRVLYRIDKYKHSLIIKDCGFPDEGEYVVTAG 12825
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
D A ++I+ P + F +HL TV+E + SC + E ++W + GRE
Sbjct: 12826 QDKSVA---ELLIIEAPTE---FVEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGRE 12878
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
IK + F L KD D +Y C G D KS+
Sbjct: 12879 IKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC------GVDDRKSRARLFVE------- 12925
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
+ + + PQ I F+A++ D + V+W K + QG + +
Sbjct: 12926 -----EIPVEIIRPPQDILEAPGADVVFLAELNKDKV-EVQWLKNN-MIIVQGDKHQMMS 12978
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDL 1769
+G +L+I D D G YR +A +K E+ L++ K + + DL
Sbjct: 12979 EGKIHRLQICDIKPRDQGEYRFIAKDK----EARAKLELAAAPKIKTADQDL 13026
Score = 107 bits (267), Expect = 4e-23
Identities = 165/757 (21%), Positives = 279/757 (36%), Gaps = 138/757 (18%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G+S +L+C ++G P V+WY+ D ++ + +++ F++ +A L+ + + DSG
Sbjct: 949 VTVIEGESVTLECHISGYPSPKVTWYREDYQIESSIDFQITFQSGIARLLIREAFAEDSG 1008
Query: 186 EYICRAENSVGEVSSSTFLTVQ------------EQKLPPSFSR--QLRDVQET------ 305
+ C A N G VS+S +L VQ +K+ R + RDV T
Sbjct: 1009 RFTCTAVNEAGTVSTSCYLAVQVSEEFEKETTAVAEKITTEEKRFVESRDVVMTDTSITE 1068
Query: 306 -----------------------VGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTS 416
G +VFEC V G+ V W K G PL G + S
Sbjct: 1069 EHAGPGEPAAPFFITKPVVQKLVEGGSIVFECQVGGNPKPHVYWKKSGVPLTSGYRYKVS 1128
Query: 417 FLDNV--ATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI-------LTEGRNPPFFDI 569
+ L I T AG+Y+ N G S+SA L+ L + + +
Sbjct: 1129 YNKQTGECRLVISMTFADDAGEYTIVIRNKHGETSASASLLEEADYESLMKSQQEMLYQT 1188
Query: 570 PLAPV--DAVVGESA------DFECHVTGTQP-IKVAWAKDNREIRSGGNYQISYLENSA 722
+ + VGE A ++E Q I+ AKD +R+ Q ++ +
Sbjct: 1189 QVTAFVQEPKVGEIAPGYVYSEYEKEYEKEQALIRKKMAKDTVMVRTFVEDQEFHISSFE 1248
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
I +++ + E G++ ++ E I F ++ + EG
Sbjct: 1249 ERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESE-AIEAGFDLRV-KNYRILEGMGVT 1306
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITF-KNNALLLQVK
Search to RefSeqMP_Rel49
BLASTX 2.2.24 [Aug-08-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MLTL1_0024_C11
(2001 letters)
Database: RefSeq49_MP.fasta
30,036 sequences; 15,617,559 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|NP_035782.3| titin isoform N2-A [Mus musculus]. 1207 0.0
Alignment gi|NP_001019891.2| hemicentin 1 [Mus musculus]. 195 1e-49
Alignment gi|XP_003084534.1| PREDICTED: hemicentin-2 [Mus musculus]. 174 2e-43
Alignment gi|XP_003086264.1| PREDICTED: hemicentin-2 [Mus musculus]. 173 4e-43
Alignment gi|NP_954603.2| obscurin isoform 2 [Mus musculus]. 167 3e-41
Alignment gi|NP_001164983.1| obscurin isoform 1 [Mus musculus]. 160 3e-39
Alignment gi|NP_062286.2| roundabout homolog 1 precursor [Mus musculus]. 157 4e-38
Alignment gi|NP_001074739.1| Down syndrome cell adhesion molecule-like pr... 153 5e-37
Alignment gi|NP_112451.1| Down syndrome cell adhesion molecule homolog [M... 152 9e-37
Alignment gi|NP_780758.3| roundabout homolog 2 [Mus musculus]. 151 2e-36
>ref|NP_035782.3| titin isoform N2-A [Mus musculus].
Length = 33467
Score = 1207 bits (3124), Expect = 0.0
Identities = 594/656 (90%), Positives = 622/656 (94%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTAT KMHF+NNVATLVF QVDS+DS
Sbjct: 7963 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATCKMHFKNNVATLVFTQVDSSDS 8022
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV
Sbjct: 8023 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 8082
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SW+KDG+PLKD PNIQTSFLDN+ATLNIF+TDRS +GQYSCTATNPIGSASS A+LILTE
Sbjct: 8083 SWYKDGKPLKDSPNIQTSFLDNIATLNIFKTDRSLSGQYSCTATNPIGSASSGAKLILTE 8142
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
G+NPPFFDIPLAP+DAVVGESAD ECHVTGTQPIKV WAKDNREIRSGGNYQISYLENSA
Sbjct: 8143 GKNPPFFDIPLAPMDAVVGESADLECHVTGTQPIKVTWAKDNREIRSGGNYQISYLENSA 8202
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
HLTI+KVDKGD+GQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF+
Sbjct: 8203 HLTIVKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFK 8262
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LEGRVAGSQPI+VAWYKNNVEIHPT+NCEI FKNNALLLQVK+ASM DAGLYTCK +NDA
Sbjct: 8263 LEGRVAGSQPITVAWYKNNVEIHPTSNCEIMFKNNALLLQVKRASMADAGLYTCKATNDA 8322
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GSALCTSSIVIKEPKKPPVFDQHL PVT SEG+ +QLSCHV+GSEPIRIQWLKAGRE+KP
Sbjct: 8323 GSALCTSSIVIKEPKKPPVFDQHLAPVTASEGDSVQLSCHVQGSEPIRIQWLKAGREVKP 8382
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
SDRCSFSFA+GTA+LE K+ KAD+GDYVCKASNVAGSDTSK KVT
Sbjct: 8383 SDRCSFSFASGTAMLELKETAKADSGDYVCKASNVAGSDTSKCKVTIKEKPAAAPAAKKA 8442
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRI IHQKGD
Sbjct: 8443 AVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRILIHQKGD 8502
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLK 1802
EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV+ERKKQEKIEGDLRAMLKKTP LK
Sbjct: 8503 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPALK 8562
Query: 1803 KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEEETHRL 1970
KG+GEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFE+LKQSQEEETHRL
Sbjct: 8563 KGSGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRL 8618
Score = 495 bits (1274), Expect = e-140
Identities = 256/578 (44%), Positives = 355/578 (61%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++ +VGDS SLQCQ+AGTPEI VSW+KGDTKLR T Y+ +F NNVATLVFN+V NDS
Sbjct: 6081 PLEASVGDSVSLQCQVAGTPEITVSWFKGDTKLRSTPEYRTYFTNNVATLVFNKVSINDS 6140
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C AENS+G +S T +QE++LPPSF+RQL+D+++TVGLPV C ++GS PI V
Sbjct: 6141 GEYTCMAENSIGTAASKTIFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQV 6200
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W++DG L+D N+Q SF+DNVATL I QTD S +GQYSC+A+NP+G+ASS+ARL E
Sbjct: 6201 CWYRDGVLLRDDENLQMSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSTARLTARE 6260
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ PFFDI +D + GESADFECHVTG QP++V W+KDN+EIR GGNY I+ + N+
Sbjct: 6261 PKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTP 6320
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
HL ILKV KGD+GQYTC A N+VGKD C+AQL++KE PP F KKL + +G S +
Sbjct: 6321 HLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE---PPKFIKKLDASKVAKQGESIQ 6377
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE +++GS I V W++N+ E+H + ++F N+ LL + +AS D G Y C+ N
Sbjct: 6378 LECKISGSPEIKVVWFRNDSELHESWKYNMSFVNSVALLTINEASAEDTGDYICEAHNGV 6437
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G A C++++ + K PPVF Q PV +G + L C + G+ P + W+K ++++
Sbjct: 6438 GDASCSTALKV---KAPPVFTQKPPPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRS 6494
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + N L ++ D G+Y CKA+N GSDT V
Sbjct: 6495 SKKFKITSKNFDTSLHIFNLEAPDIGEYHCKATNEVGSDTCACTV-----KFKEPPRFVK 6549
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+ + +P ++ V + G PI +V W K K + + + I +
Sbjct: 6550 KLSDASTLIGDPVELQAVVE---------GFQPI-SVVWLKDKGEVIRESENVRISFVDN 6599
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L++ + SG Y C N G E + L V E
Sbjct: 6600 IATLQLGSPEASQSGKYVCQIKNDAGMRECSAVLTVLE 6637
Score = 491 bits (1264), Expect = e-139
Identities = 260/577 (45%), Positives = 357/577 (61%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ +G+ +LQC++ GTPEI +SWYK TKLR YKM F+NNVA+LV N+VD +D G
Sbjct: 7023 VEAAIGEPITLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVG 7082
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY C+AENSVG V+SS L ++E+KLPPSF+R+L+DV ET+G PV FEC ++GSEP+ VS
Sbjct: 7083 EYTCKAENSVGAVASSAVLVIKERKLPPSFARKLKDVHETLGFPVAFECRINGSEPLQVS 7142
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+KDG LKD N+Q SF+ +VATL I QTD+S GQY+C+A+NP+G+ASSSA+LIL+E
Sbjct: 7143 WYKDGELLKDDANLQMSFVHHVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLILSEH 7202
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PPFFD+ VD +GES F+CHVTGT PIK+ WAKDNREIR GGNY+++ +EN+A
Sbjct: 7203 EVPPFFDLKPVSVDLALGESGSFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTAT 7262
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
LT+LKV KGD GQYTCYA N GKDSC+AQL ++E PP F KKL ++ + R
Sbjct: 7263 LTVLKVAKGDAGQYTCYASNVAGKDSCSAQLGVQE---PPRFIKKLDQSRIVKQDEYTRY 7319
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ GS I V WYK+ VEI ++ ++F+++ +L++ S+ D+G YTC+ N AG
Sbjct: 7320 ECKIGGSPEIKVLWYKDEVEIQESSKFRMSFEDSVAILEMHSLSVEDSGDYTCEARNAAG 7379
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
SA ++S+ +KE PPVF + PV +G + L C ++G+ P ++ W K RE++
Sbjct: 7380 SASSSTSLKVKE---PPVFRKKPFPVETLKGADVHLECELQGTPPFQVSWHKDKRELRSG 7436
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ N + +V AD G+Y CKA+N GSDT VT
Sbjct: 7437 KKYKIMSENLLTSIHILNVDTADIGEYQCKATNDVGSDTCVGSVTMKAPPQFVK------ 7490
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
KL +S V +TT G +PI +V W K K + + I+I +
Sbjct: 7491 ---KLTDISTIIGKEVQLQTTIE-----GAEPI-SVAWFKDKGEIVRESDNIWISYSENI 7541
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L+ ++G Y C N G E L V E
Sbjct: 7542 ATLQFSRAEPANAGKYTCQIKNDAGMQECYATLSVLE 7578
Score = 324 bits (830), Expect = 2e-88
Identities = 192/582 (32%), Positives = 287/582 (49%), Gaps = 3/582 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+KVT GD+ +L+C ++GTPE+ W+K +L YK+ F N V+ L V DSG
Sbjct: 7589 IKVTTGDTCTLECTVSGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVVPGDSG 7648
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y +N VG+ S + V ++ +PPSF+R+L++ G VV EC V GS PISV
Sbjct: 7649 VYSFEVQNPVGKDSCKVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVL 7708
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WF DG + G QT+ DN L + + + AG Y+C ATN GS SA L +
Sbjct: 7709 WFHDGNEISSGRKYQTTLTDNTCALTVNMLEEADAGDYTCIATNVAGSDECSAPLTV--- 7765
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
R PP F P+D + G + F V G+ P V+W K + E+ G +S ++
Sbjct: 7766 REPPSFVQKPDPMDVLTGSNVTFTSIVKGSPPFTVSWFKGSTELVPGARCNVSLQDSVGE 7825
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + VD +G+YTC NE G+ SCT +L +K P F K+L++ E +G L
Sbjct: 7826 LELFDVDTSQSGEYTCIVSNEAGRASCTTRLFVK---APAIFVKRLNDYSIE-KGKPLIL 7881
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
EG +G+ PISV W KN + + + C IT + +L++ +++ D+G Y C + N +G
Sbjct: 7882 EGTFSGTPPISVTWKKNGINVIASQRCNITTTEKSAILEILSSTVEDSGQYNCYIENASG 7941
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
C++ I+I E PP F + L PV V+ G+ L C + G+ I + W K +++P+
Sbjct: 7942 KDSCSAQILILE---PPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPT 7998
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
C F N A L F V +D+G+Y+C+A N G +S + +T
Sbjct: 7999 ATCKMHFKNNVATLVFTQVDSSDSGEYICRAENSVGEVSSSTFLT--------------- 8043
Query: 1446 VDGKLFFVSEPQSIRVVEKTT---ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
V + S + +R V++T F V G +V W K + L I
Sbjct: 8044 VQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWYK-DGKPLKDSPNIQTSFL 8102
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
+ A L I T ++ SG Y C A N G S L + E K
Sbjct: 8103 DNIATLNIFKTDRSLSGQYSCTATNPIGSASSGAKLILTEGK 8144
Score = 321 bits (822), Expect = 2e-87
Identities = 188/581 (32%), Positives = 287/581 (49%), Gaps = 3/581 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VTVG++ +L+C++AGTPE+ V WYK L + +K F N +++L V+ D+G Y
Sbjct: 5709 VTVGETCALECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVEKEDAGTY 5768
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
+ +N+VG+ S + + V ++ +PPSF+R+L+D +G + EC V+GS PIS++WF
Sbjct: 5769 TFQVQNNVGKSSCTAVVDVSDRMVPPSFTRRLKDTGGVLGTSCILECKVAGSSPISIAWF 5828
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
+ + G QT+F DNV TL + D S G Y+C A N GS A L + E
Sbjct: 5829 HEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANVAGSDECRALLTVQE--- 5885
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP F P++ + G++ F + GT P KV W + RE+ G I + + A L
Sbjct: 5886 PPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGARELVKGNRCNIYFEDTVAELE 5945
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
+ +D +G+YTC N G+ SCT +L +KE P +F KKLS+ E G S LEG
Sbjct: 5946 LFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE---PATFVKKLSDHSVE-PGKSIILEG 6001
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
G+ PISV W K+ V I P+ C I +L++ ++ GDAG Y+C++ N+AG
Sbjct: 6002 TYTGTLPISVTWKKDGVSITPSERCNIVTTEKTCILEILSSTKGDAGHYSCEIENEAGRD 6061
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
C + + E PP F L P+ S G+ + L C V G+ I + W K +++ +
Sbjct: 6062 ACDALVSTLE---PPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWFKGDTKLRSTPE 6118
Query: 1272 CSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVD 1451
F N A L F V+ D+G+Y C A N G+ SK+ +
Sbjct: 6119 YRTYFTNNVATLVFNKVSINDSGEYTCMAENSIGTAASKT---------------IFRIQ 6163
Query: 1452 GKLFFVSEPQSIRVVEKTT---ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+ S + ++ +E+T T ++ G V W + L + + +
Sbjct: 6164 ERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYR-DGVLLRDDENLQMSFVDN 6222
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
A L+I T + SG Y C A N G S L E KK
Sbjct: 6223 VATLKILQTDLSHSGQYSCSASNPLGTASSTARLTAREPKK 6263
Score = 318 bits (816), Expect = 8e-87
Identities = 189/573 (32%), Positives = 284/573 (49%), Gaps = 1/573 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G+S L+C+++G+PEI V W++ D++L + Y M F N+VA L N+ + D+G+YIC
Sbjct: 6373 GESIQLECKISGSPEIKVVWFRNDSELHESWKYNMSFVNSVALLTINEASAEDTGDYICE 6432
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A N VG+ S ST L V K PP F+++ V G V+ +C +SG+ P V W KD
Sbjct: 6433 AHNGVGDASCSTALKV---KAPPVFTQKPPPVGALKGSDVILQCEISGTPPFEVVWVKDR 6489
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ ++ + + + +L+IF + G+Y C ATN +GS + + + E PP
Sbjct: 6490 KQVRSSKKFKITSKNFDTSLHIFNLEAPDIGEYHCKATNEVGSDTCACTVKFKE---PPR 6546
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE-IRSGGNYQISYLENSAHLTIL 737
F L+ ++G+ + + V G QPI V W KD E IR N +IS+++N A L +
Sbjct: 6547 FVKKLSDASTLIGDPVELQAVVEGFQPISVVWLKDKGEVIRESENVRISFVDNIATLQLG 6606
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+ +G+Y C N+ G C+A L + E P+ + E + T GN F LE V
Sbjct: 6607 SPEASQSGKYVCQIKNDAGMRECSAVLTVLE----PATIVEKPEPMTVTTGNPFTLECVV 6662
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
AG+ +S W+K+ E+ + ITF N L++ A M D GLYT +V N G + C
Sbjct: 6663 AGTPELSAKWFKDGRELSSGSRHHITFVRNLASLKIPSAEMNDKGLYTFEVENRVGKSSC 6722
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
T S+ + + PP F + L + + G + L C V GS PI + W G EI S +C
Sbjct: 6723 TVSVHVSDRVVPPSFVRRLKDTSATLGASVVLECRVSGSAPISVGWFLDGNEIISSPKCQ 6782
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SFA+ L + +D G Y C A+NVAG D S + +T V
Sbjct: 6783 SSFADNVCTLTLSSLEPSDTGAYTCVAANVAGQDESSAVLT---------------VQEP 6827
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F P S+ V+ + TF + + G P VKW KG R+L G I + +LE
Sbjct: 6828 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGS-RELVSGEACTISLEDFVTELE 6886
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ + SG Y C+ N G +L V E
Sbjct: 6887 LLEVEPGQSGDYSCLVTNDAGSASCTTHLFVKE 6919
Score = 316 bits (810), Expect = 4e-86
Identities = 190/580 (32%), Positives = 284/580 (48%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ VT G+ +L+C +AGTPE+ W+K +L + + + F N+A+L + ND
Sbjct: 6647 PMTVTTGNPFTLECVVAGTPELSAKWFKDGRELSSGSRHHITFVRNLASLKIPSAEMNDK 6706
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y EN VG+ S + + V ++ +PPSF R+L+D T+G VV EC VSGS PISV
Sbjct: 6707 GLYTFEVENRVGKSSCTVSVHVSDRVVPPSFVRRLKDTSATLGASVVLECRVSGSAPISV 6766
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WF DG + P Q+SF DNV TL + + S G Y+C A N G SSA L + E
Sbjct: 6767 GWFLDGNEIISSPKCQSSFADNVCTLTLSSLEPSDTGAYTCVAANVAGQDESSAVLTVQE 6826
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F+ V+ + G S F + GT P KV W K +RE+ SG IS +
Sbjct: 6827 ---PPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVSGEACTISLEDFVT 6883
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L +L+V+ G +G Y+C N+ G SCT L +KE P +F K+L++T ET G+
Sbjct: 6884 ELELLEVEPGQSGDYSCLVTNDAGSASCTTHLFVKE---PATFVKRLADTSVET-GSPIV 6939
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE +G+ PISV+W KN + + NC IT + +L++ ++++ D Y C + N+A
Sbjct: 6940 LEATYSGTPPISVSWMKNEYPLSQSPNCGITTTEKSSILEILESTIEDYAQYACLIENEA 6999
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G +C + + + E PP F + L V + GE + L C V G+ IRI W K +++
Sbjct: 7000 GQDICEALVSVLE---PPYFIEPLEHVEAAIGEPITLQCKVDGTPEIRISWYKEHTKLRS 7056
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ F N A L V +D G+Y CKA N G+ S + +
Sbjct: 7057 APAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPPS----- 7111
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
F + + + F ++ G V W K L + +
Sbjct: 7112 -------FARKLKDVHETLGFPVAFECRINGSEPLQVSWYK-DGELLKDDANLQMSFVHH 7163
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
A L+I T ++ G Y C A N G S+ L ++E +
Sbjct: 7164 VATLQILQTDQSHVGQYNCSASNPLGTASSSAKLILSEHE 7203
Score = 308 bits (789), Expect = 1e-83
Identities = 183/573 (31%), Positives = 282/573 (49%), Gaps = 1/573 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G + +LQ + G+ I V W KG ++ KM F N VA L V + G+Y C
Sbjct: 3944 GQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSNGVAVLTIPDVQISLGGKYTCL 4003
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
AEN G +S L V+E P + +Q T G P E VSG+ + W+KDG
Sbjct: 4004 AENEAGSQTSVGELIVKE---PAKIIERAELIQVTAGDPATLEYTVSGTPELKPKWYKDG 4060
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
RPL + SF +N+A L + + +GQY+ +N +GS+S + + P
Sbjct: 4061 RPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPL 4120
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F PL VD+VVG + +C + G+ P++V+W KD +E+ + YQI+++E +A L I +
Sbjct: 4121 FTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKDGKELTASDRYQIAFVEGTASLEISR 4180
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
VD D G +TC A N VG + L ++E PPSF K + G++ L+
Sbjct: 4181 VDMNDAGNFTCRATNSVGSKDSSGALIVQE---PPSFVTKPGSR-DVLPGSAVCLKSAFQ 4236
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
GS P+++ W+K + E+ +C IT + + L++ D+G YTCKVSN AGS C+
Sbjct: 4237 GSAPLTIKWFKGDKELVSGGSCYITKETSESSLELYAVKTSDSGTYTCKVSNVAGSVECS 4296
Query: 1101 SSIVIKEPKKPPVFDQHLTP-VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ + +KE P F + L P + +G+ QL+C V G+ PI+I W RE++ S +
Sbjct: 4297 ADLFVKE---PATFIEKLEPSQLLKKGDGTQLACKVTGTPPIKITWFANDRELRESSKHK 4353
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SFA TAVL DV D+G+Y+C+A N AGSD V V
Sbjct: 4354 MSFAESTAVLRLTDVAIEDSGEYMCEAQNEAGSDHCTGIV---------------IVKES 4398
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
+F E +SI V+++ +A+V G P + W K L G + + L+
Sbjct: 4399 PYFTKEFKSIEVLKEYDVMLLAEVAGTPPFEITWFKDN-TTLRSGRKYKTFLQDQLVSLQ 4457
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ D+G Y+C N+ G + + + E
Sbjct: 4458 VLKFVAADAGEYQCRVTNEVGSSTCSARVTLRE 4490
Score = 308 bits (789), Expect = 1e-83
Identities = 198/585 (33%), Positives = 280/585 (47%), Gaps = 12/585 (2%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G L+ +GTP I V+W K + + + A L DSG+Y C
Sbjct: 7876 GKPLILEGTFSGTPPISVTWKKNGINVIASQRCNITTTEKSAILEILSSTVEDSGQYNCY 7935
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
EN+ G+ S S + + E PP F +QL V+ TVG +C ++G+ I VSW+K
Sbjct: 7936 IENASGKDSCSAQILILE---PPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGD 7992
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
L+ + F +NVATL Q D S +G+Y C A N +G SSS L + E + PP
Sbjct: 7993 TKLRPTATCKMHFKNNVATLVFTQVDSSDSGEYICRAENSVGEVSSSTFLTVQEQKLPPS 8052
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L V VG FEC V+G++PI V+W KD + ++ N Q S+L+N A L I K
Sbjct: 8053 FSRQLRDVQETVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPNIQTSFLDNIATLNIFK 8112
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
D+ +GQY+C A N +G S A+L + E PP F L+ ++ G S LE V
Sbjct: 8113 TDRSLSGQYSCTATNPIGSASSGAKLILTEGKNPPFFDIPLA-PMDAVVGESADLECHVT 8171
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+QPI V W K+N EI N +I++ N+ L + K GD+G YTC N+ G CT
Sbjct: 8172 GTQPIKVTWAKDNREIRSGGNYQISYLENSAHLTIVKVDKGDSGQYTCYAVNEVGKDSCT 8231
Query: 1101 SSIVIKEPKKPPVFDQHLT-PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ + IKE PP F + L+ V +EG +L V GS+PI + W K EI P+ C
Sbjct: 8232 AQLNIKERLIPPSFTKKLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNVEIHPTSNCE 8291
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
F N +L+ K + ADAG Y CKA+N AGS S +
Sbjct: 8292 IMFKNNALLLQVKRASMADAGLYTCKATNDAGSALCTSSIV------------------- 8332
Query: 1458 LFFVSEPQSIRVVEKTTATFIAK-----------VGGDPIPNVKWTKGKWRQLNQGGRIF 1604
+ EP+ V ++ A A G +PI ++W K R++ R
Sbjct: 8333 ---IKEPKKPPVFDQHLAPVTASEGDSVQLSCHVQGSEPI-RIQWLKA-GREVKPSDRCS 8387
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
A LE+++T K DSG Y C A N G S + + E+
Sbjct: 8388 FSFASGTAMLELKETAKADSGDYVCKASNVAGSDTSKCKVTIKEK 8432
Score = 302 bits (774), Expect = 6e-82
Identities = 187/579 (32%), Positives = 274/579 (47%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+ G L+C+L GTP VSW+K +LR YK+ N + ++ VD+ D
Sbjct: 7401 PVETLKGADVHLECELQGTPPFQVSWHKDKRELRSGKKYKIMSENLLTSIHILNVDTADI 7460
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+A N VG S T + K PP F ++L D+ +G V + + G+EPISV
Sbjct: 7461 GEYQCKATNDVG---SDTCVGSVTMKAPPQFVKKLTDISTIIGKEVQLQTTIEGAEPISV 7517
Query: 363 SWFKD-GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
+WFKD G +++ NI S+ +N+ATL + + + AG+Y+C N G A L +
Sbjct: 7518 AWFKDKGEIVRESDNIWISYSENIATLQFSRAEPANAGKYTCQIKNDAGMQECYATLSVL 7577
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E P + G++ EC V+GT + W KD +E+ S Y+IS+
Sbjct: 7578 E---PAAIVEKPESIKVTTGDTCTLECTVSGTPELSTKWFKDGKELTSDNKYKISFFNKV 7634
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
+ L I+ V GD+G Y+ N VGKDSC + + +R+IPPSFT+KL ET G+S
Sbjct: 7635 SGLKIINVVPGDSGVYSFEVQNPVGKDSCKVSIQVSDRIIPPSFTRKLKET-NGLSGSSV 7693
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
+E +V GS PISV W+ + EI + T +N L V DAG YTC +N
Sbjct: 7694 VMECKVYGSPPISVLWFHDGNEISSGRKYQTTLTDNTCALTVNMLEEADAGDYTCIATNV 7753
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS C++ + ++E PP F Q P+ V G + + V+GS P + W K E+
Sbjct: 7754 AGSDECSAPLTVRE---PPSFVQKPDPMDVLTGSNVTFTSIVKGSPPFTVSWFKGSTELV 7810
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
P RC+ S + LE DV + +G+Y C SN AG + +++
Sbjct: 7811 PGARCNVSLQDSVGELELFDVDTSQSGEYTCIVSNEAGRASCTTRL-------------- 7856
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V FV + + G P +V W K + R I
Sbjct: 7857 -FVKAPAIFVKRLNDYSIEKGKPLILEGTFSGTPPISVTWKKNGINVI-ASQRCNITTTE 7914
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A LEI +T DSG Y C N G+ + + + E
Sbjct: 7915 KSAILEILSSTVEDSGQYNCYIENASGKDSCSAQILILE 7953
Score = 300 bits (767), Expect = 4e-81
Identities = 189/576 (32%), Positives = 275/576 (47%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
+G S L+C++AG+ I ++W+ TK+ A Y+ F +NV TL N +DS+D G Y C
Sbjct: 5807 LGTSCILECKVAGSSPISIAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGSYTC 5866
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKD 377
A N G LTVQE PPSF ++ ++ G + F + G+ P V WF+
Sbjct: 5867 VAANVAGSDECRALLTVQE---PPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRG 5923
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
R L G F D VA L +F D S +G+Y+C +N G AS + RL + E P
Sbjct: 5924 ARELVKGNRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE---PA 5980
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F L+ G+S E TGT PI V W KD I I E + L IL
Sbjct: 5981 TFVKKLSDHSVEPGKSIILEGTYTGTLPISVTWKKDGVSITPSERCNIVTTEKTCILEIL 6040
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
KGD G Y+C NE G+D+C A ++ E PP F +L E +E + G+S L+ +V
Sbjct: 6041 SSTKGDAGHYSCEIENEAGRDACDALVSTLE---PPYFVTEL-EPLEASVGDSVSLQCQV 6096
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
AG+ I+V+W+K + ++ T F NN L K S+ D+G YTC N G+A
Sbjct: 6097 AGTPEITVSWFKGDTKLRSTPEYRTYFTNNVATLVFNKVSINDSGEYTCMAENSIGTAAS 6156
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ I+E + PP F + L + + G + L+C + GS PI++ W + G ++ +
Sbjct: 6157 KTIFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQ 6216
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF + A L+ + +G Y C ASN G+ +S +++T
Sbjct: 6217 MSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSTARLTAREPKKSP----------- 6265
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
FF +P SI V+ +A F V G V W+K +++ GG I G+ L
Sbjct: 6266 -FFDIKPVSIDVIAGESADFECHVTGAQPMRVTWSKDN-KEIRPGGNYTITCVGNTPHLR 6323
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
I K DSG Y C A N G+ + L V E K
Sbjct: 6324 ILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPK 6359
Score = 294 bits (752), Expect = 2e-79
Identities = 178/564 (31%), Positives = 274/564 (48%), Gaps = 1/564 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G L+ +GTP I VSW K + L + + + L + D +Y
Sbjct: 6932 VETGSPIVLEATYSGTPPISVSWMKNEYPLSQSPNCGITTTEKSSILEILESTIEDYAQY 6991
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C EN G+ ++V E PP F L V+ +G P+ +C V G+ I +SW+
Sbjct: 6992 ACLIENEAGQDICEALVSVLE---PPYFIEPLEHVEAAIGEPITLQCKVDGTPEIRISWY 7048
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K+ L+ P + F +NVA+L I + D S G+Y+C A N +G+ +SSA L++ E +
Sbjct: 7049 KEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKL 7108
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP F L V +G FEC + G++P++V+W KD ++ N Q+S++ + A L
Sbjct: 7109 PPSFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGELLKDDANLQMSFVHHVATLQ 7168
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
IL+ D+ GQY C A N +G S +A+L + E +PP F K +V+ G S +
Sbjct: 7169 ILQTDQSHVGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLK-PVSVDLALGESGSFKC 7227
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
V G+ PI + W K+N EI P N ++T N L V K + GDAG YTC SN AG
Sbjct: 7228 HVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVAKGDAGQYTCYASNVAGKD 7287
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPV-TVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
C++ + ++E PP F + L V + E+ + C + GS I++ W K EI+ S
Sbjct: 7288 SCSAQLGVQE---PPRFIKKLDQSRIVKQDEYTRYECKIGGSPEIKVLWYKDEVEIQESS 7344
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ SF + A+LE ++ D+GDY C+A N AGS +S + + V
Sbjct: 7345 KFRMSFEDSVAILEMHSLSVEDSGDYTCEARNAAGSASSSTSL---------------KV 7389
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F +P + ++ ++ G P V W K K R+L G + I +
Sbjct: 7390 KEPPVFRKKPFPVETLKGADVHLECELQGTPPFQVSWHKDK-RELRSGKKYKIMSENLLT 7448
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHG 1700
+ I + D G Y+C A N G
Sbjct: 7449 SIHILNVDTADIGEYQCKATNDVG 7472
Score = 293 bits (749), Expect = 4e-79
Identities = 173/577 (29%), Positives = 280/577 (48%), Gaps = 1/577 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++V G + + + GTP V W++G +L ++F + VA L +D + S
Sbjct: 5895 PLEVLPGKNITFTSVIRGTPPFKVGWFRGARELVKGNRCNIYFEDTVAELELFNIDISQS 5954
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C N+ G+ S +T L V+E P +F ++L D G ++ E +G+ PISV
Sbjct: 5955 GEYTCVVSNNAGQASCTTRLFVKE---PATFVKKLSDHSVEPGKSIILEGTYTGTLPISV 6011
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KDG + + L I + + AG YSC N G + A L
Sbjct: 6012 TWKKDGVSITPSERCNIVTTEKTCILEILSSTKGDAGHYSCEIENEAGRDACDA---LVS 6068
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP+F L P++A VG+S +C V GT I V+W K + ++RS Y+ + N A
Sbjct: 6069 TLEPPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWFKGDTKLRSTPEYRTYFTNNVA 6128
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L KV D+G+YTC A N +G + I+ER +PPSF ++L + +E+T G
Sbjct: 6129 TLVFNKVSINDSGEYTCMAENSIGTAASKTIFRIQERQLPPSFARQLKD-IEQTVGLPVT 6187
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L R+ GS PI V WY++ V + N +++F +N L++ + + +G Y+C SN
Sbjct: 6188 LTCRLNGSAPIQVCWYRDGVLLRDDENLQMSFVDNVATLKILQTDLSHSGQYSCSASNPL 6247
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G+A T+ + +EPKK P FD + V GE CHV G++P+R+ W K +EI+P
Sbjct: 6248 GTASSTARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRVTWSKDNKEIRP 6307
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ + T L V K D+G Y C+A+N G D ++++
Sbjct: 6308 GGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLS-------------- 6353
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFI-AKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V F+ + + +V ++ + + K+ G P V W + +L++ + +
Sbjct: 6354 -VKEPPKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWFRND-SELHESWKYNMSFVN 6411
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
A L I + + D+G Y C A N G+ + L+V
Sbjct: 6412 SVALLTINEASAEDTGDYICEAHNGVGDASCSTALKV 6448
Score = 293 bits (749), Expect = 4e-79
Identities = 174/590 (29%), Positives = 281/590 (47%), Gaps = 1/590 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKL-RPTATYKMHFRNNVATLVFNQVDSNDS 182
+ +G LQ + G I V+W+K ++ R + + + N+ATL F++ + ++
Sbjct: 7495 ISTIIGKEVQLQTTIEGAEPISVAWFKDKGEIVRESDNIWISYSENIATLQFSRAEPANA 7554
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y C+ +N G L+V E P + + ++ T G EC VSG+ +S
Sbjct: 7555 GKYTCQIKNDAGMQECYATLSVLE---PAAIVEKPESIKVTTGDTCTLECTVSGTPELST 7611
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WFKDG+ L + SF + V+ L I +G YS NP+G S + +++
Sbjct: 7612 KWFKDGKELTSDNKYKISFFNKVSGLKIINVVPGDSGVYSFEVQNPVGKDSCKVSIQVSD 7671
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F L + + G S EC V G+ PI V W D EI SG YQ + +N+
Sbjct: 7672 RIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGNEISSGRKYQTTLTDNTC 7731
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
LT+ +++ D G YTC A N G D C+A L ++E PPSF +K + ++ G++
Sbjct: 7732 ALTVNMLEEADAGDYTCIATNVAGSDECSAPLTVRE---PPSFVQK-PDPMDVLTGSNVT 7787
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
V GS P +V+W+K + E+ P A C ++ +++ L++ +G YTC VSN+A
Sbjct: 7788 FTSIVKGSPPFTVSWFKGSTELVPGARCNVSLQDSVGELELFDVDTSQSGEYTCIVSNEA 7847
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G A CT+ + + K P +F + L ++ +G+ L L G+ PI + W K G +
Sbjct: 7848 GRASCTTRLFV---KAPAIFVKRLNDYSIEKGKPLILEGTFSGTPPISVTWKKNGINVIA 7904
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S RC+ + +A+LE T D+G Y C N +G D+ +++
Sbjct: 7905 SQRCNITTTEKSAILEILSSTVEDSGQYNCYIENASGKDSCSAQILILEPP--------- 7955
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+FV + + ++V +A+ ++ G P V W KG +L +H K +
Sbjct: 7956 ------YFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGD-TKLRPTATCKMHFKNN 8008
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLR 1772
A L +DSG Y C A N GE+ S+ L V E+K LR
Sbjct: 8009 VATLVFTQVDSSDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR 8058
Score = 292 bits (748), Expect = 6e-79
Identities = 181/576 (31%), Positives = 282/576 (48%), Gaps = 1/576 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
+ GDSA L+C++ G+PEI V WY+ + +L + Y+M F ++VA + N + + DSG++
Sbjct: 5429 IKAGDSARLECKITGSPEIQVVWYRNEHELTASDKYQMTFIDSVAVIQMNSLGTEDSGDF 5488
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
IC A+N G S ST + V+E PP FS V+ V EC +SG+ P V W+
Sbjct: 5489 ICEAQNPAGSTSCSTKVIVKE---PPVFSSFPPIVETLKNTEVSLECELSGTPPFEVVWY 5545
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KD R L+ + + + A+++I + + G+Y C A N +GS + + L E
Sbjct: 5546 KDKRQLRSSKKYKVASKNFHASIHILNVESTDIGEYHCKAQNEVGSDACVCAVKLKE--- 5602
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE-IRSGGNYQISYLENSAHL 728
PP F L + V GE A+ + + G QPI V W K+ E IR N +IS++ N A L
Sbjct: 5603 PPKFISKLNSLTVVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRISFVNNVATL 5662
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
KV+ + G+Y C N+ G A L + E P+ + + ++ T G + LE
Sbjct: 5663 QFAKVEPANAGKYICQVKNDGGVRENMATLTVLE----PAVIIEKAGSMTVTVGETCALE 5718
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+VAG+ +SV WYK+ + + + +F N L++ DAG YT +V N+ G
Sbjct: 5719 CKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVEKEDAGTYTFQVQNNVGK 5778
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
+ CT+ + + + PP F + L G L C V GS PI I W +I
Sbjct: 5779 SSCTAVVDVSDRMVPPSFTRRLKDTGGVLGTSCILECKVAGSSPISIAWFHEKTKIVSGA 5838
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ +F++ L+ + +D G Y C A+NVAGSD ++ +T V
Sbjct: 5839 KYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANVAGSDECRALLT---------------V 5883
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
FV EP+ + V+ TF + + G P V W +G R+L +G R I+ + A
Sbjct: 5884 QEPPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGA-RELVKGNRCNIYFEDTVA 5942
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+LE+ + + SG Y CV N G+ L V E
Sbjct: 5943 ELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE 5978
Score = 291 bits (746), Expect = 1e-78
Identities = 175/565 (30%), Positives = 268/565 (47%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ VT GD A+LQ + +GT EI W+K +L YK+ + V+ L + DSG
Sbjct: 4594 IDVTQGDPATLQVKFSGTKEISAKWFKDGQELTLGPKYKISVTDTVSILKIISTEKKDSG 4653
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY +N VG S + V + +PPSF+++LR + G + EC V+GS PIS+
Sbjct: 4654 EYTFEVQNDVGRSSCKASINVLDLIIPPSFTKKLRKMDSIKGSFIDLECIVAGSHPISIQ 4713
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKD + + + SF DN A L I Q + + +G Y+C+ATN G + S L + E
Sbjct: 4714 WFKDDQEISASDKHKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHSQCSGHLTVKE- 4772
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP+F D G + V GT P+ + W KDN+E+ G + + S
Sbjct: 4773 --PPYFVEKPQSQDVNPGTRVQLKALVGGTAPMTIKWFKDNKELHPGAARSVWKDDTSTI 4830
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + D+G Y C N+VG S A + +KE PP F KK S + G S
Sbjct: 4831 LELFSAKAADSGTYICQLSNDVGTTSSKATIFVKE---PPQFIKKPSPVLVLRNGQSTTF 4887
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E +V G+ I V+WY + EI I+F + Q+ A + ++G Y C+ NDAG
Sbjct: 4888 ECQVTGTPEIRVSWYLDGNEITDLRKYGISFVDGLATFQISNARVENSGTYVCEARNDAG 4947
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
+A C+ + +KE PP+F + L PV V + ++L C V G+ P + WLK +EI+
Sbjct: 4948 TASCSIELKVKE---PPIFIRELEPVEVVKDSDVELECEVMGTTPFEVTWLKNNKEIRSG 5004
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + S L +D G+Y C +N GS ++V
Sbjct: 5005 KKYTMSEKMSVFYLHITKCDPSDVGEYQCIIANEGGSCACSARVALKEPPS--------- 5055
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
F+ + +++ V K++ATF + V G P ++ W K + L + + I +
Sbjct: 5056 ------FIKKIENVTTVLKSSATFQSTVAGSPPISITWLKDD-QILEENDNVHISFEDSV 5108
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHG 1700
A L++R SG Y C A N+ G
Sbjct: 5109 ATLQVRSVDNGHSGRYTCQAKNESG 5133
Score = 289 bits (740), Expect = 5e-78
Identities = 172/606 (28%), Positives = 295/606 (48%), Gaps = 1/606 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G +A+ Q L G+ I V+W K + ++ +M F NNVA+L + ++ G+Y+C+
Sbjct: 4506 GGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQ 4565
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A+N G S L+V+E P + + + T G P + SG++ IS WFKDG
Sbjct: 4566 AKNDAGIQRCSALLSVKE---PATIMEEAVSIDVTQGDPATLQVKFSGTKEISAKWFKDG 4622
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ L GP + S D V+ L I T++ +G+Y+ N +G +S A + + + PP
Sbjct: 4623 QELTLGPKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKASINVLDLIIPPS 4682
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L +D++ G D EC V G+ PI + W KD++EI + ++ S+ +N+A L I +
Sbjct: 4683 FTKKLRKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASDKHKFSFHDNTAFLEISQ 4742
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
++ D+G YTC A N+ G C+ L +KE PP F +K ++ + G +L+ V
Sbjct: 4743 LEGTDSGTYTCSATNKAGHSQCSGHLTVKE---PPYFVEK-PQSQDVNPGTRVQLKALVG 4798
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+ P+++ W+K+N E+HP A + + + +L++ A D+G Y C++SND G+
Sbjct: 4799 GTAPMTIKWFKDNKELHPGAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGTTSSK 4858
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTV-SEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
++I +KE PP F + +PV V G+ C V G+ IR+ W G EI +
Sbjct: 4859 ATIFVKE---PPQFIKKPSPVLVLRNGQSTTFECQVTGTPEIRVSWYLDGNEITDLRKYG 4915
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF +G A + + ++G YVC+A N AG+ + ++ V
Sbjct: 4916 ISFVDGLATFQISNARVENSGTYVCEARNDAGTASCSIEL---------------KVKEP 4960
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F+ E + + VV+ + +V G V W K +++ G + + +K L
Sbjct: 4961 PIFIRELEPVEVVKDSDVELECEVMGTTPFEVTWLKNN-KEIRSGKKYTMSEKMSVFYLH 5019
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAGE 1817
I +D G Y+C+ N+ G + + + E K ++ +LK + +
Sbjct: 5020 ITKCDPSDVGEYQCIIANEGGSCACSARVALKEPPSFIKKIENVTTVLKSSATFQSTVAG 5079
Query: 1818 EEEIDI 1835
I I
Sbjct: 5080 SPPISI 5085
Score = 289 bits (740), Expect = 5e-78
Identities = 179/578 (30%), Positives = 274/578 (47%), Gaps = 1/578 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTK-LRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
V G+ A LQ + G I V W K + +R + ++ F NNVATL F +V+ ++G+
Sbjct: 5615 VVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRISFVNNVATLQFAKVEPANAGK 5674
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
YIC+ +N G + LTV E P + + TVG EC V+G+ +SV W
Sbjct: 5675 YICQVKNDGGVRENMATLTVLE---PAVIIEKAGSMTVTVGETCALECKVAGTPELSVEW 5731
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+KDG+ L + SF + +++L I ++ AG Y+ N +G +S +A + +++
Sbjct: 5732 YKDGKLLTSSQKHKFSFYNKISSLKILSVEKEDAGTYTFQVQNNVGKSSCTAVVDVSDRM 5791
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP F L V+G S EC V G+ PI +AW + +I SG YQ ++ +N L
Sbjct: 5792 VPPSFTRRLKDTGGVLGTSCILECKVAGSSPISIAWFHEKTKIVSGAKYQTTFSDNVCTL 5851
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
+ +D D G YTC A N G D C A L ++E PPSF K+ E +E G +
Sbjct: 5852 QLNSLDSSDMGSYTCVAANVAGSDECRALLTVQE---PPSFVKE-PEPLEVLPGKNITFT 5907
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+ G+ P V W++ E+ C I F++ L++ + +G YTC VSN+AG
Sbjct: 5908 SVIRGTPPFKVGWFRGARELVKGNRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQ 5967
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
A CT+ + +KEP F + L+ +V G+ + L G+ PI + W K G I PS+
Sbjct: 5968 ASCTTRLFVKEPA---TFVKKLSDHSVEPGKSIILEGTYTGTLPISVTWKKDGVSITPSE 6024
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
RC+ T +LE TK DAG Y C+ N AG D + V+
Sbjct: 6025 RCNIVTTEKTCILEILSSTKGDAGHYSCEIENEAGRDACDALVSTLEPP----------- 6073
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
+FV+E + + + + +V G P V W KG +L + + A
Sbjct: 6074 ----YFVTELEPLEASVGDSVSLQCQVAGTPEITVSWFKGD-TKLRSTPEYRTYFTNNVA 6128
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
L + DSG Y C+A N G S ++ ER+
Sbjct: 6129 TLVFNKVSINDSGEYTCMAENSIGTAASKTIFRIQERQ 6166
Score = 286 bits (732), Expect = 4e-77
Identities = 180/607 (29%), Positives = 279/607 (45%), Gaps = 1/607 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT D +L+C +AGTPE+ V W K ++ P+ + M F NNVA+ V DSG
Sbjct: 5156 VDVTEKDPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSG 5215
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y + EN G S +L V +Q +PPSF+++L + + +G + EC VSGS PIS
Sbjct: 5216 QYTFKVENDFGSSSCDAYLRVLDQDIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQ 5275
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKDG+ + + +N +L + + Y+C +N G + S L + E
Sbjct: 5276 WFKDGKEISTSAKYRLVCHENTVSLEVSNLELEDTANYTCKVSNVAGDNACSGILTVKE- 5334
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F + A+ + +F+ + GT P K+ W KD+ E+ SG I +++
Sbjct: 5335 --PPSFLVKPERQQAIPDSTVEFKAVLKGTPPFKIKWLKDDVELVSGPKCFIGLEGSTSF 5392
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + VD TGQYTC N+V PP F KKL + G+S RL
Sbjct: 5393 LNLYSVDSSKTGQYTCQVTNDVE---------------PPKFVKKLEASKIIKAGDSARL 5437
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ GS I V WY+N E+ + ++TF ++ ++Q+ D+G + C+ N AG
Sbjct: 5438 ECKITGSPEIQVVWYRNEHELTASDKYQMTFIDSVAVIQMNSLGTEDSGDFICEAQNPAG 5497
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
S C++ +++KE PPVF V + + L C + G+ P + W K R+++ S
Sbjct: 5498 STSCSTKVIVKE---PPVFSSFPPIVETLKNTEVSLECELSGTPPFEVVWYKDKRQLRSS 5554
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + N A + +V D G+Y CKA N GSD V
Sbjct: 5555 KKYKVASKNFHASIHILNVESTDIGEYHCKAQNEVGSDACVCAVKLKEPPK--------- 5605
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
F+S+ S+ VV A A + G +V+W K K + + I I +
Sbjct: 5606 ------FISKLNSLTVVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRISFVNNV 5659
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLK- 1802
A L+ ++G Y C N G E+ L V E + G + + +T L+
Sbjct: 5660 ATLQFAKVEPANAGKYICQVKNDGGVRENMATLTVLEPAVIIEKAGSMTVTVGETCALEC 5719
Query: 1803 KGAGEEE 1823
K AG E
Sbjct: 5720 KVAGTPE 5726
Score = 284 bits (727), Expect = 2e-76
Identities = 174/564 (30%), Positives = 269/564 (47%), Gaps = 1/564 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G S L+ GT I V+W K + P+ + L D+G Y
Sbjct: 5991 VEPGKSIILEGTYTGTLPISVTWKKDGVSITPSERCNIVTTEKTCILEILSSTKGDAGHY 6050
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C EN G + ++ E PP F +L ++ +VG V +C V+G+ I+VSWF
Sbjct: 6051 SCEIENEAGRDACDALVSTLE---PPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWF 6107
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K L+ P +T F +NVATL + + +G+Y+C A N IG+A+S + E +
Sbjct: 6108 KGDTKLRSTPEYRTYFTNNVATLVFNKVSINDSGEYTCMAENSIGTAASKTIFRIQERQL 6167
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP F L ++ VG C + G+ PI+V W +D +R N Q+S+++N A L
Sbjct: 6168 PPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQMSFVDNVATLK 6227
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
IL+ D +GQY+C A N +G S TA+L +E P F K +++ G S E
Sbjct: 6228 ILQTDLSHSGQYSCSASNPLGTASSTARLTAREPKKSPFFDIK-PVSIDVIAGESADFEC 6286
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
V G+QP+ V W K+N EI P N IT N L++ K GD+G YTC+ +ND G
Sbjct: 6287 HVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKD 6346
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVS-EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
+C++ + +KE PP F + L V+ +GE +QL C + GS I++ W + E+ S
Sbjct: 6347 MCSAQLSVKE---PPKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWFRNDSELHESW 6403
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ + SF N A+L + + D GDY+C+A N G + + + V
Sbjct: 6404 KYNMSFVNSVALLTINEASAEDTGDYICEAHNGVGDASCSTAL---------------KV 6448
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F +P + ++ + ++ G P V W K + +Q+ + I K +
Sbjct: 6449 KAPPVFTQKPPPVGALKGSDVILQCEISGTPPFEVVWVKDR-KQVRSSKKFKITSKNFDT 6507
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHG 1700
L I + D G Y C A N+ G
Sbjct: 6508 SLHIFNLEAPDIGEYHCKATNEVG 6531
Score = 282 bits (721), Expect = 8e-76
Identities = 169/577 (29%), Positives = 280/577 (48%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++VT GD A+L+ ++GTPE+ WYK L + Y++ F+NN+A L F + +DSG
Sbjct: 4032 IQVTAGDPATLEYTVSGTPELKPKWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSG 4091
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y N VG S T TV ++ + P F++ LR+V VG +C ++GS P+ VS
Sbjct: 4092 QYTFEISNEVGSSSCETTFTVLDRDIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVS 4151
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKDG+ L Q +F++ A+L I + D + AG ++C ATN +GS SS LI+ E
Sbjct: 4152 WFKDGKELTASDRYQIAFVEGTASLEISRVDMNDAGNFTCRATNSVGSKDSSGALIVQE- 4210
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F D + G + + G+ P+ + W K ++E+ SGG+ I+ + +
Sbjct: 4211 --PPSFVTKPGSRDVLPGSAVCLKSAFQGSAPLTIKWFKGDKELVSGGSCYITKETSESS 4268
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + V D+G YTC N G C+A L +KE P +F +KL + +G+ +L
Sbjct: 4269 LELYAVKTSDSGTYTCKVSNVAGSVECSADLFVKE---PATFIEKLEPSQLLKKGDGTQL 4325
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+V G+ PI + W+ N+ E+ ++ +++F + +L++ ++ D+G Y C+ N+AG
Sbjct: 4326 ACKVTGTPPIKITWFANDRELRESSKHKMSFAESTAVLRLTDVAIEDSGEYMCEAQNEAG 4385
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
S CT +++KE P F + + V + + L V G+ P I W K ++
Sbjct: 4386 SDHCTGIVIVKE---SPYFTKEFKSIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSG 4442
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + L+ ADAG+Y C+ +N GS T ++VT
Sbjct: 4443 RKYKTFLQDQLVSLQVLKFVAADAGEYQCRVTNEVGSSTCSARVTLREPPS--------- 4493
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
F+ + ++ + TA F A + G V W K ++ + I + + +
Sbjct: 4494 ------FIKKIEATSSLRGGTAAFQATLKGSLPITVTWLKDN-DEITEDDNIRMTFENNV 4546
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L + G Y C A N G + L V E
Sbjct: 4547 ASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE 4583
Score = 271 bits (692), Expect = 2e-72
Identities = 169/566 (29%), Positives = 260/566 (45%), Gaps = 1/566 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V + SA+ Q +AG+P I ++W K D L + F ++VATL VD+ SG
Sbjct: 5063 VTTVLKSSATFQSTVAGSPPISITWLKDDQILEENDNVHISFEDSVATLQVRSVDNGHSG 5122
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C+A+N G FL VQE P + + V T PV EC V+G+ + V
Sbjct: 5123 RYTCQAKNESGIERCYAFLLVQE---PAQIIEKAKSVDVTEKDPVTLECVVAGTPELKVK 5179
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W KDG+ + SF +NVA+ I + +GQY+ N GS+S A L + +
Sbjct: 5180 WLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQ 5239
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F L +D V+G S EC V+G+ PI W KD +EI + Y++ EN+
Sbjct: 5240 DIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHENTVS 5299
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + ++ DT YTC N G ++C+ L +KE PPSF K E + ++
Sbjct: 5300 LEVSNLELEDTANYTCKVSNVAGDNACSGILTVKE---PPSFLVK-PERQQAIPDSTVEF 5355
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+ + G+ P + W K++VE+ C I + + L + G YTC+V+ND
Sbjct: 5356 KAVLKGTPPFKIKWLKDDVELVSGPKCFIGLEGSTSFLNLYSVDSSKTGQYTCQVTNDV- 5414
Query: 1086 SALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
+PP F + L + G+ +L C + GS I++ W + E+
Sbjct: 5415 --------------EPPKFVKKLEASKIIKAGDSARLECKITGSPEIQVVWYRNEHELTA 5460
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
SD+ +F + AV++ + D+GD++C+A N AGS + +KV
Sbjct: 5461 SDKYQMTFIDSVAVIQMNSLGTEDSGDFICEAQNPAGSTSCSTKV--------------- 5505
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
V F S P + ++ T + ++ G P V W K K RQL + + K
Sbjct: 5506 IVKEPPVFSSFPPIVETLKNTEVSLECELSGTPPFEVVWYKDK-RQLRSSKKYKVASKNF 5564
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHG 1700
A + I + TD G Y C A N+ G
Sbjct: 5565 HASIHILNVESTDIGEYHCKAQNEVG 5590
Score = 269 bits (688), Expect = 5e-72
Identities = 173/567 (30%), Positives = 267/567 (47%), Gaps = 1/567 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P + G +A LQC++AGT V+W+K ++R + Y++ + L + +S D
Sbjct: 3845 PADIVRGANALLQCEIAGTGPFEVNWFKDKKQIRSSKKYRLFTQKTFVYLEISSFNSADV 3904
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y C N VG+ ++E PP+F +++ D G V + AV GSEPISV
Sbjct: 3905 GDYECVVANEVGKCGCVATHLLKE---PPTFVKKVDDFTALAGQTVTLQAAVRGSEPISV 3961
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W K +K+ I+ SF + VA L I S G+Y+C A N GS +S LI+ E
Sbjct: 3962 MWMKGQEVIKEDGKIKMSFSNGVAVLTIPDVQISLGGKYTCLAENEAGSQTSVGELIVKE 4021
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P + G+ A E V+GT +K W KD R + + Y+IS+ N A
Sbjct: 4022 ---PAKIIERAELIQVTAGDPATLEYTVSGTPELKPKWYKDGRPLVASKKYRISFKNNIA 4078
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + D+GQYT NEVG SC + +R I P FTK L V+ G + R
Sbjct: 4079 QLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPLFTKPL-RNVDSVVGGACR 4137
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L+ ++AGS P+ V+W+K+ E+ + +I F L++ + M DAG +TC+ +N
Sbjct: 4138 LDCKIAGSLPMRVSWFKDGKELTASDRYQIAFVEGTASLEISRVDMNDAGNFTCRATNSV 4197
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GS + +++++E PP F V G + L +GS P+ I+W K +E+
Sbjct: 4198 GSKDSSGALIVQE---PPSFVTKPGSRDVLPGSAVCLKSAFQGSAPLTIKWFKGDKELVS 4254
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
C + + LE V +D+G Y CK SNVAGS + +
Sbjct: 4255 GGSCYITKETSESSLELYAVKTSDSGTYTCKVSNVAGSVECSADL--------------- 4299
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIA-KVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V F+ + + ++++K T +A KV G P + W R+L + + +
Sbjct: 4300 FVKEPATFIEKLEPSQLLKKGDGTQLACKVTGTPPIKITWFAND-RELRESSKHKMSFAE 4358
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHG 1700
A L + D DSG Y C A N+ G
Sbjct: 4359 STAVLRLTDVAIEDSGEYMCEAQNEAG 4385
Score = 268 bits (685), Expect = 1e-71
Identities = 170/581 (29%), Positives = 263/581 (45%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++V +G A C++ G P + W+K ++ + + N V++L + D
Sbjct: 3470 PLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIYESDKCSIRSSNYVSSLEILRTQVVDC 3529
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+A N G VS + LTV E PP+F + + + VG F C VSG+ I +
Sbjct: 3530 GEYTCKASNEYGSVSCTATLTVTEA-YPPTFLSRPKALTTFVGKAAKFLCTVSGTPVIEI 3588
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W KDG L P+ + + DN +L + G YSC A+N G+ A L + +
Sbjct: 3589 IWQKDGAALSPSPDCRVTDADNKHSLELSNLTVQDRGIYSCKASNKFGADICQAELTIID 3648
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L V + + + EC V + + + W+KD +++ +G +Y+I + + A
Sbjct: 3649 ---KPHFIKELEAVQSAINKKIHLECQVDEDRKVTITWSKDGQKLPAGKDYKIYFEDKIA 3705
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I D+G YTC A NE G S +A + ++E PPSF KK+ + G S R
Sbjct: 3706 SLEIPLAKLKDSGTYTCTASNEAGSSSSSAAVAVRE---PPSFVKKVDPSYLMLPGESAR 3762
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L ++ GS I V W+KNN E+ + ++F N+ +L + + D+G Y+C+ +ND
Sbjct: 3763 LHCKLKGSPVIQVTWFKNNKELSESNTVRMSFVNSEAILDITDVKVDDSGTYSCEATNDV 3822
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GS C++ +VIKE PP F + L P + G L C + G+ P + W K ++I+
Sbjct: 3823 GSDSCSTEVVIKE---PPSFIKTLEPADIVRGANALLQCEIAGTGPFEVNWFKDKKQIRS 3879
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + LE AD GDY C +N G
Sbjct: 3880 SKKYRLFTQKTFVYLEISSFNSADVGDYECVVANEVGK---------------CGCVATH 3924
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+ FV + + T T A V G +V W KG+ + + G+I +
Sbjct: 3925 LLKEPPTFVKKVDDFTALAGQTVTLQAAVRGSEPISVMWMKGQ-EVIKEDGKIKMSFSNG 3983
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
A L I D + G Y C+A N+ G S L V E K
Sbjct: 3984 VAVLTIPDVQISLGGKYTCLAENEAGSQTSVGELIVKEPAK 4024
Score = 264 bits (674), Expect = 2e-70
Identities = 170/579 (29%), Positives = 271/579 (46%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+V L+C++ GT V+W K + ++R Y M + +V L + D +D
Sbjct: 4969 PVEVVKDSDVELECEVMGTTPFEVTWLKNNKEIRSGKKYTMSEKMSVFYLHITKCDPSDV 5028
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C N G + S + ++E PPSF +++ +V + F+ V+GS PIS+
Sbjct: 5029 GEYQCIIANEGGSCACSARVALKE---PPSFIKKIENVTTVLKSSATFQSTVAGSPPISI 5085
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD + L++ N+ SF D+VATL + D +G+Y+C A N G A L++ E
Sbjct: 5086 TWLKDDQILEENDNVHISFEDSVATLQVRSVDNGHSGRYTCQAKNESGIERCYAFLLVQE 5145
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P VD + EC V GT +KV W KD ++I + +S+ N A
Sbjct: 5146 ---PAQIIEKAKSVDVTEKDPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVA 5202
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
I V K D+GQYT N+ G SC A L + ++ IPPSFTKKL++ +++ G+S
Sbjct: 5203 SFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQDIPPSFTKKLTK-MDKVLGSSIH 5261
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
+E +V+GS PIS W+K+ EI +A + N + L+V + D YTCKVSN A
Sbjct: 5262 MECKVSGSLPISAQWFKDGKEISTSAKYRLVCHENTVSLEVSNLELEDTANYTCKVSNVA 5321
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G C+ + +KEP V + + S EF + ++G+ P +I+WLK E+
Sbjct: 5322 GDNACSGILTVKEPPSFLVKPERQQAIPDSTVEFKAV---LKGTPPFKIKWLKDDVELVS 5378
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+C T+ L V + G Y C+ +N D K
Sbjct: 5379 GPKCFIGLEGSTSFLNLYSVDSSKTGQYTCQVTN----DVEPPK---------------- 5418
Query: 1443 XVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
FV + ++ ++++ +A K+ G P V W + + +L + +
Sbjct: 5419 -------FVKKLEASKIIKAGDSARLECKITGSPEIQVVWYRNE-HELTASDKYQMTFID 5470
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A +++ DSG + C A N G + + V E
Sbjct: 5471 SVAVIQMNSLGTEDSGDFICEAQNPAGSTSCSTKVIVKE 5509
Score = 262 bits (670), Expect = 6e-70
Identities = 174/578 (30%), Positives = 263/578 (45%), Gaps = 1/578 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ + L+CQ+ ++ ++W K KL YK++F + +A+L DSG
Sbjct: 3659 VQSAINKKIHLECQVDEDRKVTITWSKDGQKLPAGKDYKIYFEDKIASLEIPLAKLKDSG 3718
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-GLPVVFECAVSGSEPISV 362
Y C A N G SSS + V+E PPSF +++ + G C + GS I V
Sbjct: 3719 TYTCTASNEAGSSSSSAAVAVRE---PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQV 3775
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+WFK+ + L + ++ SF+++ A L+I +G YSC ATN +GS S S +++ E
Sbjct: 3776 TWFKNNKELSESNTVRMSFVNSEAILDITDVKVDDSGTYSCEATNDVGSDSCSTEVVIKE 3835
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F L P D V G +A +C + GT P +V W KD ++IRS Y++ +
Sbjct: 3836 ---PPSFIKTLEPADIVRGANALLQCEIAGTGPFEVNWFKDKKQIRSSKKYRLFTQKTFV 3892
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
+L I + D G Y C NEVGK C A +KE PP+F KK+ + G +
Sbjct: 3893 YLEISSFNSADVGDYECVVANEVGKCGCVATHLLKE---PPTFVKKVDD-FTALAGQTVT 3948
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L+ V GS+PISV W K I +++F N +L + + G YTC N+A
Sbjct: 3949 LQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSNGVAVLTIPDVQISLGGKYTCLAENEA 4008
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GS +++KEP K + + V+ G+ L V G+ ++ +W K GR +
Sbjct: 4009 GSQTSVGELIVKEPAK---IIERAELIQVTAGDPATLEYTVSGTPELKPKWYKDGRPLVA 4065
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + SF N A L+F D+G Y + SN GS + ++ T
Sbjct: 4066 SKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDR---------- 4115
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
D F +++ V K+ G V W K ++L R I
Sbjct: 4116 --DIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFK-DGKELTASDRYQIAFVEG 4172
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A LEI D+G + C A N G +S+ L V E
Sbjct: 4173 TASLEISRVDMNDAGNFTCRATNSVGSKDSSGALIVQE 4210
Score = 238 bits (606), Expect = 2e-62
Identities = 158/580 (27%), Positives = 263/580 (45%), Gaps = 5/580 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G + L+ G+ + + W+KGD +L + + + ++L V ++DSG Y
Sbjct: 4223 VLPGSAVCLKSAFQGSAPLTIKWFKGDKELVSGGSCYITKETSESSLELYAVKTSDSGTY 4282
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-GLPVVFECAVSGSEPISVSW 368
C+ N G V S L V+E P +F +L Q G C V+G+ PI ++W
Sbjct: 4283 TCKVSNVAGSVECSADLFVKE---PATFIEKLEPSQLLKKGDGTQLACKVTGTPPIKITW 4339
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
F + R L++ + SF ++ A L + +G+Y C A N GS + +I+ E
Sbjct: 4340 FANDRELRESSKHKMSFAESTAVLRLTDVAIEDSGEYMCEAQNEAGSDHCTGIVIVKES- 4398
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
P+F ++ + V GT P ++ W KDN +RSG Y+ + L
Sbjct: 4399 --PYFTKEFKSIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFLQDQLVSL 4456
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
+LK D G+Y C NEVG +C+A++ ++E PPSF KK+ E G + +
Sbjct: 4457 QVLKFVSFTKKLSETVEETEGNSFRLE 908
+ +D D G YTC A N G D C A L ++E PPSF K+ E +E G +
Sbjct: 5858 QLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE---PPSFVKE-PEPLEVLPGKNVTFT 5913
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+ G+ P V W++ E+ C I F++ L++ + +G YTC VSN+AG
Sbjct: 5914 SVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQ 5973
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
A CT+ + +KEP F + L+ +V G+ + L G+ PI + W K G I S+
Sbjct: 5974 ASCTTRLFVKEPA---AFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSE 6030
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+C+ T +LE + TK DAG Y C+ N AG D + V+
Sbjct: 6031 KCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPP----------- 6079
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
+FV+E + + + + +V G P V W KG +L + + A
Sbjct: 6080 ----YFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGD-TKLRPTPEYRTYFTNNVA 6134
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
L DSG Y C A N G S ++ ER+
Sbjct: 6135 TLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQ 6172
Score = 276 bits (706), Expect = 5e-74
Identities = 175/581 (30%), Positives = 284/581 (48%), Gaps = 3/581 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++V L ++AGTP ++W+K +T LR YK ++++ +L + + D+
Sbjct: 4401 PIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADA 4460
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY CR N VG S +T++E PPSF +++ G F+ + GS PI+V
Sbjct: 4461 GEYQCRVTNEVGSSICSARVTLRE---PPSFIKKIESTSSLRGGTAAFQATLKGSLPITV 4517
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD + + NI+ +F +NVA+L + + G+Y C A N G SA L + E
Sbjct: 4518 TWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE 4577
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P +D G+ A + +GT+ I W KD +E+ G Y+IS + +
Sbjct: 4578 ---PATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVS 4634
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I+ +K D+G+YT N+VG+ SC A++N+ + +IPPSFTKKL + ++ +G+
Sbjct: 4635 ILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKK-MDSIKGSFID 4693
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE VAGS PIS+ W+K++ EI + + +F +N L++ + D+G YTC +N A
Sbjct: 4694 LECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKA 4753
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G C+ + +KE PP F + V+ +QL V G+ P+ I+W K +E+
Sbjct: 4754 GHNQCSGHLTVKE---PPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHS 4810
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + LE D+G Y+C+ SN G+ TSK+ +
Sbjct: 4811 GAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATL--------------- 4855
Query: 1443 XVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDPIPNVKW--TKGKWRQLNQGGRIFIHQ 1613
V F+ +P + V+ + TF ++ G P V W + + + G FI
Sbjct: 4856 FVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFI-- 4913
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A +I +SG Y C A N G ++ L+V E
Sbjct: 4914 -DGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKE 4953
Score = 275 bits (702), Expect = 1e-73
Identities = 173/579 (29%), Positives = 279/579 (48%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+V L+C++ GTP V+W K + ++R + Y + R +V L + D +D+
Sbjct: 4963 PVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDT 5022
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C N G S ST + ++E PPSF +++ + + F+ V+GS PIS+
Sbjct: 5023 GEYQCIVSNEGGSCSCSTRVALKE---PPSFIKKIENTTTVLKSSATFQSTVAGSPPISI 5079
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD + L + N+ SF+D+VATL I D +G+Y+C A N G A L++ E
Sbjct: 5080 TWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQE 5139
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P VD + EC V GT +KV W KD ++I + +S+ N A
Sbjct: 5140 ---PAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVA 5196
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
I V K D+GQYT N+ G SC A L + ++ IPPSFTKKL++ +++ G+S
Sbjct: 5197 SFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTK-MDKVLGSSIH 5255
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
+E +V+GS PIS W+K+ EI +A + ++ L+V + D YTCKVSN A
Sbjct: 5256 MECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVA 5315
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G C+ + +KEP V + S EF + ++G+ P +I+W K E+
Sbjct: 5316 GDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAI---LKGTPPFKIKWFKDDVELVS 5372
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+C T+ L V + G Y C +N GSD+ + +
Sbjct: 5373 GPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTML--------------- 5417
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFI-AKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V FV + ++ ++V+ ++ + K+ G P V W + + +L + +
Sbjct: 5418 LVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNE-HELPASDKYRMTFID 5476
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A +++ + + DSG + C A N G + + V E
Sbjct: 5477 SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKE 5515
Score = 272 bits (696), Expect = 7e-73
Identities = 177/579 (30%), Positives = 269/579 (46%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+ + L+CQ+ ++ V+W K KL P YK+ F + +ATL DS
Sbjct: 3652 PVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDS 3711
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-GLPVVFECAVSGSEPIS 359
G Y+C A N G S S +TV+E PPSF +++ + G C + GS I
Sbjct: 3712 GTYVCTASNEAGSSSCSATVTVRE---PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQ 3768
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V+WFK+ + L + ++ F+++ A L+I +G YSC A N +GS S S +++
Sbjct: 3769 VTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIK 3828
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E PP F L P D V G +A +C V+GT P +++W KD ++IRS Y++ ++
Sbjct: 3829 E---PPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSL 3885
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I + D G+Y C NEVGK C A +KE PP+F KK+ + + G +
Sbjct: 3886 VCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKE---PPTFVKKVDDLI-ALGGQTV 3941
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L+ V GS+PISV W K I +++F N +L + + G YTC N+
Sbjct: 3942 TLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENE 4001
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS +++KEP K + + V+ G+ L V G+ ++ +W K GR +
Sbjct: 4002 AGSQTSVGELIVKEPAK---IIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLV 4058
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
S + SF N A L+F D+G Y + SN GS + ++ T
Sbjct: 4059 ASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDR--------- 4109
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
D FF +++ V T K+ G V W K +++ R I
Sbjct: 4110 ---DIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFK-DGKEIAASDRYRIAFVE 4165
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A LEI D+G + C A N G +S+ L V E
Sbjct: 4166 GTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQE 4204
Score = 265 bits (677), Expect = 1e-70
Identities = 172/581 (29%), Positives = 259/581 (44%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++V +G A C++ P + W+K ++ + + +++L + D
Sbjct: 3464 PLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDC 3523
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+A N G VS + LTV E PP+F + + + VG F C V+G+ I
Sbjct: 3524 GEYTCKASNEYGSVSCTATLTVTEA-YPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIET 3582
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W KDG L PN + S +N L + G YSC A+N G+ A LI+ +
Sbjct: 3583 IWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIID 3642
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L PV + + + EC V + + V W+KD +++ G +Y+I + + A
Sbjct: 3643 ---KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIA 3699
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I D+G Y C A NE G SC+A + ++E PPSF KK+ + G S R
Sbjct: 3700 TLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE---PPSFVKKVDPSYLMLPGESAR 3756
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L ++ GS I V W+KNN E+ + + F N+ +L + + D+G Y+C+ ND
Sbjct: 3757 LHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDV 3816
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GS C++ IVIKEP P F + L P + G L C V G+ P I W K ++I+
Sbjct: 3817 GSDSCSTEIVIKEP---PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRS 3873
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + LE AD G+Y C +N G
Sbjct: 3874 SKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGK---------------CGCMATH 3918
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+ FV + + + T T A V G +V W KG+ + + G+I +
Sbjct: 3919 LLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQ-EVIREDGKIKMSFSNG 3977
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
A L I D + G Y C+A N+ G S L V E K
Sbjct: 3978 VAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAK 4018
Score = 261 bits (668), Expect = 1e-69
Identities = 177/631 (28%), Positives = 292/631 (46%), Gaps = 20/631 (3%)
Frame = +3
Query: 3 PVKVTV---GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDS 173
P++ TV G A QC+++GT ++ VSWY D K++P+ ++M + L +
Sbjct: 3350 PLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYP 3408
Query: 174 NDSGEYICRAENSVGEVSSSTFLTVQ----------------EQKLPPSFSRQLRDVQET 305
D G Y A N+VG+VSS+ L+++ E K P R++ ++
Sbjct: 3409 EDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVA 3468
Query: 306 VGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSC 485
+G F C + + + WFK GR + + +++L I +T G+Y+C
Sbjct: 3469 LGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTC 3528
Query: 486 TATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKD 665
A+N GS S +A L +TE P F P + + VG++A F C VTGT I+ W KD
Sbjct: 3529 KASNEYGSVSCTATLTVTEAYPPTFLSRPKS-LTTFVGKAAKFICTVTGTPVIETIWQKD 3587
Query: 666 NREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPP 845
+ N++IS EN L + + D G Y+C A N+ G D C A+L I ++ P
Sbjct: 3588 GAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK---P 3644
Query: 846 SFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQV 1025
F K+L E V+ LE +V + ++V W K+ ++ P + +I F++ L++
Sbjct: 3645 HFIKEL-EPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEI 3703
Query: 1026 KKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP-VTVSEGEFLQLSCH 1202
A + D+G Y C SN+AGS+ C++++ ++EP P F + + P + GE +L C
Sbjct: 3704 PLAKLKDSGTYVCTASNEAGSSSCSATVTVREP---PSFVKKVDPSYLMLPGESARLHCK 3760
Query: 1203 VRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
++GS I++ W K +E+ S+ F N A+L+ DV D+G Y C+A N GSD+
Sbjct: 3761 LKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDS 3820
Query: 1383 SKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWT 1562
+++ F+ + +V T A +V G + W
Sbjct: 3821 CSTEIVIKEPPS---------------FIKTLEPADIVRGTNALLQCEVSGTGPFEISWF 3865
Query: 1563 KGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
K K +Q+ + + + LEI D G Y CV N+ G+ + E
Sbjct: 3866 KDK-KQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPP 3924
Query: 1743 KQEKIEGDLRAMLKKTPVLKKGAGEEEEIDI 1835
K DL A+ +T L+ E I +
Sbjct: 3925 TFVKKVDDLIALGGQTVTLQAAVRGSEPISV 3955
Score = 237 bits (604), Expect = 3e-62
Identities = 161/602 (26%), Positives = 275/602 (45%), Gaps = 11/602 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G + L+ G+ + + W+KG+ +L + + ++L V ++DSG Y
Sbjct: 4217 VLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTY 4276
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-GLPVVFECAVSGSEPISVSW 368
C+ N G V S L V+E P +F +L Q G C V+G+ PI ++W
Sbjct: 4277 TCKVSNVAGGVECSANLFVKE---PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITW 4333
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
F + R +K+ + SF+++ A L + +G+Y C A N GS S+ +I+ E
Sbjct: 4334 FANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKES- 4392
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
P+F P++ + V GT P ++ W KDN +RSG Y+ ++ L
Sbjct: 4393 --PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSL 4450
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
ILK D G+Y C NEVG C+A++ ++E PPSF KK+ E+ G + +
Sbjct: 4451 QILKFVAADAGEYQCRVTNEVGSSICSARVTLRE---PPSFIKKI-ESTSSLRGGTAAFQ 4506
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+ GS PI+V W K++ EI N +TF+NN L + + G Y C+ NDAG
Sbjct: 4507 ATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGI 4566
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
C++ + +KE P + + V++G+ L G++ I +W K G+E+
Sbjct: 4567 QRCSALLSVKE---PATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGS 4623
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ S + ++L+ K D+G+Y + N G + K+++ V
Sbjct: 4624 KYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARIN---------------V 4668
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFI----AKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
+ S + ++ ++ +FI G PI +++W K ++++ +
Sbjct: 4669 LDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPI-SIQWFKDD-QEISASEKYKFSFH 4726
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN------ERKKQEKIEGDLRAM 1778
+ A LEI TDSG Y C A NK G + + +L V E+ + + + + R
Sbjct: 4727 DNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQ 4786
Query: 1779 LK 1784
LK
Sbjct: 4787 LK 4788
Score = 228 bits (581), Expect = 2e-59
Identities = 159/604 (26%), Positives = 261/604 (43%), Gaps = 26/604 (4%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV V G A ++G P+ +SWYK + L K TL+ + D+
Sbjct: 3247 PVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDA 3306
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKL----------PPSFSRQLRDVQETVGLPVVFEC 332
Y C A+N G ++S L+V+ ++ PP+ L+D + G P F+C
Sbjct: 3307 AVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQC 3366
Query: 333 AVSGSEPISVSWFKDGRPLKDGPNIQTSF
Search to RefSeqCP_Rel49
BLASTX 2.2.24 [Aug-08-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MLTL1_0024_C11
(2001 letters)
Database: RefSeq49_CP.fasta
33,336 sequences; 18,874,504 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|XP_535982.2| PREDICTED: similar to titin isoform N2-B [Canis... 1237 0.0
Alignment gi|XP_547438.2| PREDICTED: similar to High Incidence of Males (... 191 2e-48
Alignment gi|XP_548414.2| PREDICTED: similar to hemicentin 1 [Canis famil... 170 4e-42
Alignment gi|XP_544815.2| PREDICTED: similar to Roundabout homolog 2 prec... 155 1e-37
Alignment gi|XP_544814.2| PREDICTED: similar to roundabout 1 isoform a [C... 154 2e-37
Alignment gi|XP_544893.2| PREDICTED: similar to Down syndrome cell adhesi... 154 3e-37
Alignment gi|XP_855194.1| PREDICTED: similar to Basement membrane-specifi... 150 4e-36
Alignment gi|XP_546425.2| PREDICTED: similar to roundabout, axon guidance... 147 5e-35
Alignment gi|XP_546506.2| PREDICTED: similar to Down syndrome cell adhesi... 144 2e-34
Alignment gi|XP_539325.2| PREDICTED: similar to obscurin, cytoskeletal ca... 144 4e-34
>ref|XP_535982.2| PREDICTED: similar to titin isoform N2-B [Canis familiaris].
Length = 12085
Score = 1237 bits (3201), Expect = 0.0
Identities = 610/656 (92%), Positives = 629/656 (95%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PVKVTVGDSASLQCQ+AGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS
Sbjct: 5505 PVKVTVGDSASLQCQIAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 5564
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEYICRAENSVGEVSSSTFL+VQEQKLPPSFSRQLRDVQETVGLPVVFEC ++GSEPISV
Sbjct: 5565 GEYICRAENSVGEVSSSTFLSVQEQKLPPSFSRQLRDVQETVGLPVVFECTINGSEPISV 5624
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SW+KDG+PLKDGPN+QTSFLDNVATLNIF+TDRS AGQYSCTATNPIGSASSSARLILTE
Sbjct: 5625 SWYKDGKPLKDGPNVQTSFLDNVATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTE 5684
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
G+NPPFFDIP+APVDAVVGESADFECHVTGTQPIKV WAKDNREIRSGGNYQISYLENSA
Sbjct: 5685 GKNPPFFDIPVAPVDAVVGESADFECHVTGTQPIKVTWAKDNREIRSGGNYQISYLENSA 5744
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
HLTILKVDKGD+GQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR
Sbjct: 5745 HLTILKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 5804
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LEGRVAGSQPI+VAWYKNN+EIHPT+NCEITFKNN LLL VKKA MGDAGLYTCKVSNDA
Sbjct: 5805 LEGRVAGSQPITVAWYKNNIEIHPTSNCEITFKNNTLLLHVKKAGMGDAGLYTCKVSNDA 5864
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GSALCTSSIVIKEPKK PVFDQHLTPVTVSEGEF+QLSCHV+GSEPIRIQWLKAGREIKP
Sbjct: 5865 GSALCTSSIVIKEPKKAPVFDQHLTPVTVSEGEFVQLSCHVQGSEPIRIQWLKAGREIKP 5924
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
SDRCSFSFANGTAVLE KDV KAD+GDYVCKASN AGSDTSKSKVT
Sbjct: 5925 SDRCSFSFANGTAVLELKDVAKADSGDYVCKASNAAGSDTSKSKVTIKDKPAAVPAAKKA 5984
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
VDG+LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRI IHQKGD
Sbjct: 5985 AVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIHIHQKGD 6044
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLK 1802
EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV+ERKKQEKIEGDLRAMLKKTPVLK
Sbjct: 6045 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPVLK 6104
Query: 1803 KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEEETHRL 1970
KG GEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEEETHRL
Sbjct: 6105 KGTGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEEETHRL 6160
Score = 503 bits (1296), Expect = e-142
Identities = 258/578 (44%), Positives = 356/578 (61%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++ +VGDS SLQCQ+AGTPEI VSWYKGDTKLRPT Y+ +F NNVATLVFN+V+ NDS
Sbjct: 3600 PLEASVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDS 3659
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+AENS+G +S T +QE++LPPSF+RQL+D+++TVGLPV C ++GS PI V
Sbjct: 3660 GEYTCKAENSIGTAASKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQV 3719
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W++DG L+D N+Q SF+DNVATL I QTD S +GQYSC+A+NP+G+ASSSARL + E
Sbjct: 3720 CWYRDGVLLRDDENLQMSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLAVRE 3779
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ PFFDI +D + GESADFECHVTG QP+++ W+KDN+EIR GGNY I+ + N+
Sbjct: 3780 PKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTP 3839
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
HL ILKV KGD+GQYTC A N+VGKD C+AQL++KE PP F KKL + G S +
Sbjct: 3840 HLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE---PPKFVKKLEASQVAKHGESIQ 3896
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE +++GS I V W++N+ E+H + ++F N+ LL + +AS D+G Y C+ N
Sbjct: 3897 LECKISGSPEIKVQWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGV 3956
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G A C++++ + K PPVF Q +PV +G + C + G+ P + W+K ++++
Sbjct: 3957 GDASCSTALTV---KAPPVFTQKPSPVGALKGSDVIFQCEISGTPPFEVVWVKDRKQVRS 4013
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + N L ++ +D G+Y CKA+N GSDT V
Sbjct: 4014 SKKFKITSKNFDTSLHILNLEASDVGEYHCKATNEVGSDTCVCSVKFKEPPR-------- 4065
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
FV + + A V G +V W K K + + I +
Sbjct: 4066 -------FVKKLSDTSTLVGDAVELRAVVEGFQPISVVWLKDKGEVIRESENTRISFIDN 4118
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L++ +DSG Y C N G E + L V E
Sbjct: 4119 IATLQLGSPKASDSGKYVCQIKNDAGTRECSAVLTVLE 4156
Score = 483 bits (1244), Expect = e-136
Identities = 250/577 (43%), Positives = 348/577 (60%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ +G+ +LQC++ GTPEI ++WYK TKLR YKM F+NNVA+LV N+VD +D G
Sbjct: 4565 VEAVIGEPTTLQCKVDGTPEIRIAWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDIG 4624
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY C+AENSVG V+SS L ++E+KLPPSF+R+L+DV ET+G PV FEC ++GSEP+ VS
Sbjct: 4625 EYTCKAENSVGAVASSAVLIIKERKLPPSFARKLKDVHETLGFPVAFECRINGSEPLQVS 4684
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+KDG LKD N+QTSF+ NVATL I QTD+S GQY+C+A+NP+G+ASSSA+LIL+E
Sbjct: 4685 WYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLILSEH 4744
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PPFFD+ VD +GES +CHVTGT PIK+ WAKDNREIR GGNY+++ +EN+A
Sbjct: 4745 EVPPFFDLKPVSVDLALGESGSLKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTAT 4804
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
LT+LKV KGD GQYTCYA N GKDSC+A L ++E PP F KKL + + R
Sbjct: 4805 LTVLKVSKGDAGQYTCYASNVAGKDSCSAHLGVQE---PPRFIKKLEPSRIVKQDEYTRY 4861
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ GS I V WYK+ EI ++ ++F ++ +L++ S+ D+G YTC+ N AG
Sbjct: 4862 ECKIGGSPEIKVLWYKDETEIQESSKFRMSFLDSVAVLEMHNLSVEDSGDYTCEARNAAG 4921
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
SA ++S+ +KE PP+F + PV +G + L C ++G+ P ++ W K RE++
Sbjct: 4922 SASSSTSLKVKE---PPIFRKKPHPVETLKGADVHLECELQGTPPFQVSWHKDKRELRSG 4978
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ N + V AD G+Y CKA+N GSDT + +T
Sbjct: 4979 KKYKIMSENFLTSIHILGVDAADIGEYQCKATNDVGSDTCVASITLKAPPR--------- 5029
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FV + I + + G +V W K K + + I++ +
Sbjct: 5030 ------FVKKLSDISTIVGEEVQLQTTIEGPEPISVVWFKDKGEIVRESDNIWVSYSENV 5083
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L+ ++G Y C N G E L V E
Sbjct: 5084 ATLQFARAETANAGKYTCQIKNDAGMQECFATLSVLE 5120
Score = 324 bits (830), Expect = 2e-88
Identities = 192/582 (32%), Positives = 287/582 (49%), Gaps = 3/582 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++VT GD+ +L+C + GTPE+ W+K +L + YK+ F N V+ L V +DSG
Sbjct: 5131 IRVTTGDTCTLECTVTGTPELSTKWFKDGKELTSDSKYKISFFNKVSGLKIINVAPSDSG 5190
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y +N VG+ S + + V ++ +PPSF+R+L++ G VV EC V GS PISVS
Sbjct: 5191 VYSFEVQNPVGKDSCTASVQVSDRIVPPSFTRKLKETHGLSGSSVVMECKVYGSPPISVS 5250
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WF +G + G QT+ DN L + + S AG Y+C ATN GS SA L +
Sbjct: 5251 WFHEGNEVSSGRKYQTTLTDNTCALTVNMLEESDAGDYTCIATNVAGSDECSAPLTV--- 5307
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
R PP F +D + G + F + GT P V+W K + E+ G +S + A
Sbjct: 5308 REPPSFVQKPEAMDVLTGANVTFTSIIKGTPPFTVSWFKGSSELAPGDRCNVSLEDCVAE 5367
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + VD +G YTC NE GK SCT L +K P F K+L++ E +G L
Sbjct: 5368 LELFGVDTTQSGDYTCIVSNEAGKASCTTHLYVK---APAKFVKRLNDYSIE-KGKPLIL 5423
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
EG G+ PISV W KN + I P+ C IT + +L++ +++ DAG Y C + N +G
Sbjct: 5424 EGTYTGTPPISVTWKKNGINITPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASG 5483
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
C++ I+I E PP F + L PV V+ G+ L C + G+ I + W K +++P+
Sbjct: 5484 KDSCSAQILILE---PPYFVKQLEPVKVTVGDSASLQCQIAGTPEIGVSWYKGDTKLRPT 5540
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
F N A L F V D+G+Y+C+A N G +S + ++
Sbjct: 5541 ATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLS--------------- 5585
Query: 1446 VDGKLFFVSEPQSIRVVEKTT---ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
V + S + +R V++T F + G +V W K + L G +
Sbjct: 5586 VQEQKLPPSFSRQLRDVQETVGLPVVFECTINGSEPISVSWYK-DGKPLKDGPNVQTSFL 5644
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
+ A L I T ++ +G Y C A N G S+ L + E K
Sbjct: 5645 DNVATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGK 5686
Score = 315 bits (806), Expect = 1e-85
Identities = 189/583 (32%), Positives = 284/583 (48%), Gaps = 11/583 (1%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G+S L+C+++G+PEI V W++ D++L + Y M F N+VA L N+ + DSG+YIC
Sbjct: 3892 GESIQLECKISGSPEIKVQWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICE 3951
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A N VG+ S ST LTV K PP F+++ V G V+F+C +SG+ P V W KD
Sbjct: 3952 AHNGVGDASCSTALTV---KAPPVFTQKPSPVGALKGSDVIFQCEISGTPPFEVVWVKDR 4008
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ ++ + + + +L+I + S G+Y C ATN +GS + + E PP
Sbjct: 4009 KQVRSSKKFKITSKNFDTSLHILNLEASDVGEYHCKATNEVGSDTCVCSVKFKE---PPR 4065
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE-IRSGGNYQISYLENSAHLTIL 737
F L+ +VG++ + V G QPI V W KD E IR N +IS+++N A L +
Sbjct: 4066 FVKKLSDTSTLVGDAVELRAVVEGFQPISVVWLKDKGEVIRESENTRISFIDNIATLQLG 4125
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
D+G+Y C N+ G C+A L + E P+ + E + T GN F LE V
Sbjct: 4126 SPKASDSGKYVCQIKNDAGTRECSAVLTVLE----PARIVEKPEPMTVTTGNPFALECVV 4181
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
AG+ +SV W+K+ E+ + ITF N +++ A M D GLY+ +V N G + C
Sbjct: 4182 AGTPELSVKWFKDGRELSADSKHHITFINKVASVKIPCAEMSDKGLYSFEVKNSVGKSTC 4241
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ S+ + + PP F + L G L C V GS PI + W + G E+ +C
Sbjct: 4242 SVSVHVSDRVVPPSFIRKLKDTNAILGASAVLECRVSGSAPISVGWFQDGNEVVSGPKCQ 4301
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF+ L + +D G Y C A+NVAGSD + +T V +
Sbjct: 4302 SSFSENVCTLSLSLLEPSDTGTYTCVAANVAGSDECSALLT--VQGPKSASHLDLFVSSR 4359
Query: 1458 LF----------FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
F P S+ V+ + F + G P VKW KG R+L G I
Sbjct: 4360 SLPPLRYPEPPSFEQVPDSVEVLPGISLIFTCVIRGTPPFKVKWFKGS-RELVSGESCTI 4418
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ D +LE+ + + SG Y C+ N+ G +L V E
Sbjct: 4419 SLEDDVTELELLEVEPSQSGDYSCLVTNEAGSASCTAHLFVKE 4461
Score = 313 bits (803), Expect = 3e-85
Identities = 192/614 (31%), Positives = 291/614 (47%), Gaps = 33/614 (5%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ VTVG++ +L+C++AGTPE+ V WYK L + +K F N ++TL V+ D+
Sbjct: 3189 PMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISTLKILSVERQDA 3248
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y + +N+VG+ S + + V ++ +PPSF+R+LRD +G + EC V+GS PISV
Sbjct: 3249 GTYTFQVQNNVGKSSCTAVVDVSDRMVPPSFTRRLRDTVGVLGTSCILECKVAGSSPISV 3308
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+WF + + G QT+F DNV TL + D S G Y+C A N GS A L + E
Sbjct: 3309 AWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANAAGSDECRAALAVQE 3368
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F P++ + G++ F + GT P KV W + RE+ G I + + A
Sbjct: 3369 ---PPSFVKEPEPLEILPGKNVTFTSVIRGTPPFKVGWFRGARELVRGDQCNIYFEDTVA 3425
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLI--------------------- 839
L + VD +G+YTC N G+ SCT +L +K L
Sbjct: 3426 ELELFNVDISQSGEYTCVVSNNAGQTSCTTRLFVKGLLACICSSDFLYAAIYVLFLGLIA 3485
Query: 840 -------PPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITF 998
P +F KKLS+ E G S LE G+ PI+V W K+ I + C I
Sbjct: 3486 VLCHSPEPATFVKKLSDHSVE-PGKSIILESTYTGTLPIAVTWKKDGFNISQSERCSIVT 3544
Query: 999 KNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSI--VIKEPKKPPVFDQHLTPVTVS 1172
+L++ ++ DAG Y+C++ N+AG +C + + VI +PP F L P+ S
Sbjct: 3545 TEKTCILEILNSTKKDAGQYSCEIENEAGKDVCKALLLNVILSSLEPPYFVTELEPLEAS 3604
Query: 1173 EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVC 1352
G+ + L C V G+ I + W K +++P+ F N A L F V D+G+Y C
Sbjct: 3605 VGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTC 3664
Query: 1353 KASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTT---ATFIA 1523
KA N G+ SK+ + + S + ++ +E+T T
Sbjct: 3665 KAENSIGTAASKT---------------VFRIQERQLPPSFARQLKDIEQTVGLPVTLTC 3709
Query: 1524 KVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
++ G V W + L + + + A L+I T + SG Y C A N G
Sbjct: 3710 RLNGSAPIQVCWYR-DGVLLRDDENLQMSFVDNVATLKILQTDLSHSGQYSCSASNPLGT 3768
Query: 1704 IESNVNLQVNERKK 1745
S+ L V E KK
Sbjct: 3769 ASSSARLAVREPKK 3782
Score = 307 bits (787), Expect = 2e-83
Identities = 192/574 (33%), Positives = 269/574 (46%), Gaps = 1/574 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G L+ GTP I V+W K + P+ + A L D+G+Y C
Sbjct: 5418 GKPLILEGTYTGTPPISVTWKKNGINITPSQRCNITTTEKSAILEIPSSTVEDAGQYNCY 5477
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
EN+ G+ S S + + E PP F +QL V+ TVG +C ++G+ I VSW+K
Sbjct: 5478 IENASGKDSCSAQILILE---PPYFVKQLEPVKVTVGDSASLQCQIAGTPEIGVSWYKGD 5534
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
L+ + F +NVATL Q D + +G+Y C A N +G SSS L + E + PP
Sbjct: 5535 TKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLSVQEQKLPPS 5594
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L V VG FEC + G++PI V+W KD + ++ G N Q S+L+N A L I K
Sbjct: 5595 FSRQLRDVQETVGLPVVFECTINGSEPISVSWYKDGKPLKDGPNVQTSFLDNVATLNIFK 5654
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
D+ GQY+C A N +G S +A+L + E PP F ++ V+ G S E V
Sbjct: 5655 TDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIPVA-PVDAVVGESADFECHVT 5713
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+QPI V W K+N EI N +I++ N+ L + K GD+G YTC N+ G CT
Sbjct: 5714 GTQPIKVTWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDSGQYTCYAVNEVGKDSCT 5773
Query: 1101 SSIVIKEPKKPPVFDQHLT-PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ + IKE PP F + L+ V +EG +L V GS+PI + W K EI P+ C
Sbjct: 5774 AQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPITVAWYKNNIEIHPTSNCE 5833
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
+F N T +L K DAG Y CK SN AGS S +
Sbjct: 5834 ITFKNNTLLLHVKKAGMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKAP----------- 5882
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F + V E V G ++W K R++ R A LE
Sbjct: 5883 -VFDQHLTPVTVSEGEFVQLSCHVQGSEPIRIQWLKA-GREIKPSDRCSFSFANGTAVLE 5940
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
++D K DSG Y C A N G S + + ++
Sbjct: 5941 LKDVAKADSGDYVCKASNAAGSDTSKSKVTIKDK 5974
Score = 304 bits (779), Expect = 2e-82
Identities = 190/607 (31%), Positives = 287/607 (47%), Gaps = 1/607 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT D +L+C +AGTPE+ V W K ++ P+ + M F NNVA+ V DSG
Sbjct: 2627 VDVTEKDPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSG 2686
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y + EN G S +L V +Q +PPSF+++L + + +G + EC VSGS PIS
Sbjct: 2687 QYTFKVENDFGSSSCDAYLRVLDQDIPPSFTKKLTKMDKILGSSIRMECKVSGSLPISAQ 2746
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKDG+ + + +N +L + + Y+C +N G + S L + E
Sbjct: 2747 WFKDGKEVSTSAKYRLVCHENTVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE- 2805
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F + A+ + +F+ + GT P K+ W KD+ E+ SG I +++
Sbjct: 2806 --PPSFLVKPERQQAIPDSTVEFKAVLKGTPPFKIKWFKDDVELASGPTCFIGLEGSTSF 2863
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + VD TGQYTC N+VG DSCT L + E PP F KKL + G+S RL
Sbjct: 2864 LNLYSVDASKTGQYTCQVTNDVGSDSCTTMLLVTE---PPKFVKKLEASKIVKAGDSARL 2920
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ GS I V WY+N E+ + +TF ++ +LQ+ D+G + C+ N AG
Sbjct: 2921 ECKITGSPEIRVVWYRNEHELQASDKYRMTFIDSVAVLQMNNLGTEDSGDFICEAQNPAG 2980
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
S C++ +++KE PPVF V + + L C + G+ P + W K R+++ S
Sbjct: 2981 STSCSTKVIVKE---PPVFSSFPPVVETLKNTEVSLECELSGTPPFEVIWYKDKRQLRSS 3037
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + N A + +V +D G+Y CKA N GSDT V
Sbjct: 3038 KKYKIASKNFHASIHILNVETSDIGEYHCKAQNEVGSDTCICTVKLKEPPR--------- 3088
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FVS+ S+ VV A A + G V+W K K + + I I +
Sbjct: 3089 ------FVSKLNSLTVVAGEPAELQAYIEGAQPIFVQWLKEKEEVIRESENIRITFVENV 3142
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLK- 1802
A L+ ++G Y C N G E+ L V E + G + + +T L+
Sbjct: 3143 ATLQFAKAEPANAGKYICQIKNDGGMRENMATLTVLEPAVIVEKAGPMTVTVGETCTLEC 3202
Query: 1803 KGAGEEE 1823
K AG E
Sbjct: 3203 KVAGTPE 3209
Score = 304 bits (779), Expect = 2e-82
Identities = 189/602 (31%), Positives = 291/602 (48%), Gaps = 22/602 (3%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ VT G+ +L+C +AGTPE+ V W+K +L + + + F N VA++ + +D
Sbjct: 4166 PMTVTTGNPFALECVVAGTPELSVKWFKDGRELSADSKHHITFINKVASVKIPCAEMSDK 4225
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y +NSVG+ + S + V ++ +PPSF R+L+D +G V EC VSGS PISV
Sbjct: 4226 GLYSFEVKNSVGKSTCSVSVHVSDRVVPPSFIRKLKDTNAILGASAVLECRVSGSAPISV 4285
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WF+DG + GP Q+SF +NV TL++ + S G Y+C A N GS SA L +
Sbjct: 4286 GWFQDGNEVVSGPKCQSSFSENVCTLSLSLLEPSDTGTYTCVAANVAGSDECSALLTVQG 4345
Query: 543 GRN--------------------PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAK 662
++ PP F+ V+ + G S F C + GT P KV W K
Sbjct: 4346 PKSASHLDLFVSSRSLPPLRYPEPPSFEQVPDSVEVLPGISLIFTCVIRGTPPFKVKWFK 4405
Query: 663 DNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP 842
+RE+ SG + IS ++ L +L+V+ +G Y+C NE G SCTA L +KE P
Sbjct: 4406 GSRELVSGESCTISLEDDVTELELLEVEPSQSGDYSCLVTNEAGSASCTAHLFVKE---P 4462
Query: 843 PSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQ 1022
+F K+L++ ET G+ LE +G+ PISV+W KN + + NC IT + +L+
Sbjct: 4463 ATFVKRLADFSVET-GSPIVLEATYSGTPPISVSWMKNESPLSQSQNCSITTTEKSTILE 4521
Query: 1023 VKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCH 1202
+ ++++ D Y+C + N+AG +C + + + E PP F + L V GE L C
Sbjct: 4522 ITESTIEDYAQYSCLIENEAGQDICDALVSVLE---PPYFIEPLQHVEAVIGEPTTLQCK 4578
Query: 1203 VRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
V G+ IRI W K +++ + F N A L V +D G+Y CKA N G+
Sbjct: 4579 VDGTPEIRIAWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDIGEYTCKAENSVGAVA 4638
Query: 1383 SKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWT 1562
S + + F + + + F ++ G V W
Sbjct: 4639 SSAVLIIKERKLPPS------------FARKLKDVHETLGFPVAFECRINGSEPLQVSWY 4686
Query: 1563 KGKWRQLNQGG--RIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
K + F+H + A L+I T ++ G Y C A N G S+ L ++E
Sbjct: 4687 KDGVLLKDDANLQTSFVH---NVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLILSE 4743
Query: 1737 RK 1742
+
Sbjct: 4744 HE 4745
Score = 303 bits (776), Expect = 4e-82
Identities = 188/574 (32%), Positives = 282/574 (49%), Gaps = 2/574 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G + +LQ + G+ I V+W KG L+ K F N VATL+ V + +Y C
Sbjct: 1415 GQTVTLQAAVRGSEPISVTWMKGQEILKEDGKIKTSFSNGVATLIIPDVQISHGDKYTCL 1474
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
AEN G +S L V+E P + VQ T G P E V+G+ + W+KDG
Sbjct: 1475 AENEAGSQTSVGELIVKE---PAKIVERAELVQVTAGDPATLEYTVTGTPELKPKWYKDG 1531
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
RPL + SF +NVA L + + +GQY+ +N +GS+S + + PF
Sbjct: 1532 RPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEVSNEVGSSSCETTFTVLDRDIAPF 1591
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F PL V +VVG + +C + G+ P++VAW KD RE+ SG Y+ +++E +A L I
Sbjct: 1592 FTKPLRNVASVVGSACRLDCRIAGSLPMRVAWFKDGRELASGDKYRAAFVEGTASLEIHG 1651
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF-TKKLSETVEETEGNSFRLEGRV 917
VD D G +TC A N VG + L ++E PPSF TK S+ V G++ L+
Sbjct: 1652 VDLSDAGTFTCRATNSVGSKDSSGALVVQE---PPSFVTKPASKDV--LPGSAVCLKSTF 1706
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
GS P +V W K E+ +C IT + + L++ D+G YTC+V N AGS C
Sbjct: 1707 RGSGPFTVRWLKGGRELVSGGSCYITKEASESSLELYVVKTSDSGTYTCQVGNAAGSVEC 1766
Query: 1098 TSSIVIKEPKKPPVFDQHLTP-VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRC 1274
++++ +KE P F + L P + +G+ QL+C V G+ PI+I W RE+K R
Sbjct: 1767 SANLFVKE---PATFIEKLEPSQLLKKGDSTQLACKVAGTPPIKITWFANDRELKEGGRH 1823
Query: 1275 SFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDG 1454
SF TAVL +VT D+G+Y+C+A N AGSD S V
Sbjct: 1824 RMSFVESTAVLSLTEVTTEDSGEYMCEAQNEAGSDHCGS---------------ILIVKE 1868
Query: 1455 KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKL 1634
+F E + + V+++ +A+V G P ++ W K L G + + L
Sbjct: 1869 SPYFTKEFKPVEVLKEYDVMLLAEVAGTPPFDITWFKDN-TTLRSGRKYKTFIQDQLVSL 1927
Query: 1635 EIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+I TD+G Y+C N+ G + + + E
Sbjct: 1928 QILKFVATDAGEYQCRVTNEVGSSTCSARVTLRE 1961
Score = 302 bits (774), Expect = 7e-82
Identities = 183/564 (32%), Positives = 275/564 (48%), Gaps = 1/564 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G L+ +GTP I VSW K ++ L + + L + D +Y
Sbjct: 4474 VETGSPIVLEATYSGTPPISVSWMKNESPLSQSQNCSITTTEKSTILEITESTIEDYAQY 4533
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C EN G+ ++V E PP F L+ V+ +G P +C V G+ I ++W+
Sbjct: 4534 SCLIENEAGQDICDALVSVLE---PPYFIEPLQHVEAVIGEPTTLQCKVDGTPEIRIAWY 4590
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K+ L+ P + F +NVA+L I + D S G+Y+C A N +G+ +SSA LI+ E +
Sbjct: 4591 KEHTKLRSAPAYKMQFKNNVASLVINKVDHSDIGEYTCKAENSVGAVASSAVLIIKERKL 4650
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP F L V +G FEC + G++P++V+W KD ++ N Q S++ N A L
Sbjct: 4651 PPSFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQ 4710
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
IL+ D+ GQY C A N +G S +A+L + E +PP F K +V+ G S L+
Sbjct: 4711 ILQTDQSHVGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLK-PVSVDLALGESGSLKC 4769
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
V G+ PI + W K+N EI P N ++T N L V K S GDAG YTC SN AG
Sbjct: 4770 HVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVSKGDAGQYTCYASNVAGKD 4829
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPV-TVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
C++ + ++E PP F + L P V + E+ + C + GS I++ W K EI+ S
Sbjct: 4830 SCSAHLGVQE---PPRFIKKLEPSRIVKQDEYTRYECKIGGSPEIKVLWYKDETEIQESS 4886
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ SF + AVLE +++ D+GDY C+A N AGS +S + + V
Sbjct: 4887 KFRMSFLDSVAVLEMHNLSVEDSGDYTCEARNAAGSASSSTSL---------------KV 4931
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F +P + ++ ++ G P V W K K R+L G + I +
Sbjct: 4932 KEPPIFRKKPHPVETLKGADVHLECELQGTPPFQVSWHKDK-RELRSGKKYKIMSENFLT 4990
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHG 1700
+ I D G Y+C A N G
Sbjct: 4991 SIHILGVDAADIGEYQCKATNDVG 5014
Score = 297 bits (760), Expect = 3e-80
Identities = 186/579 (32%), Positives = 272/579 (46%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+ G L+C+L GTP VSW+K +LR YK+ N + ++ VD+ D
Sbjct: 4943 PVETLKGADVHLECELQGTPPFQVSWHKDKRELRSGKKYKIMSENFLTSIHILGVDAADI 5002
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+A N VG + +T+ K PP F ++L D+ VG V + + G EPISV
Sbjct: 5003 GEYQCKATNDVGSDTCVASITL---KAPPRFVKKLSDISTIVGEEVQLQTTIEGPEPISV 5059
Query: 363 SWFKD-GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
WFKD G +++ NI S+ +NVATL + + + AG+Y+C N G A L +
Sbjct: 5060 VWFKDKGEIVRESDNIWVSYSENVATLQFARAETANAGKYTCQIKNDAGMQECFATLSVL 5119
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E P + G++ EC VTGT + W KD +E+ S Y+IS+
Sbjct: 5120 E---PAAIVEKPESIRVTTGDTCTLECTVTGTPELSTKWFKDGKELTSDSKYKISFFNKV 5176
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
+ L I+ V D+G Y+ N VGKDSCTA + + +R++PPSFT+KL ET G+S
Sbjct: 5177 SGLKIINVAPSDSGVYSFEVQNPVGKDSCTASVQVSDRIVPPSFTRKLKET-HGLSGSSV 5235
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
+E +V GS PISV+W+ E+ + T +N L V DAG YTC +N
Sbjct: 5236 VMECKVYGSPPISVSWFHEGNEVSSGRKYQTTLTDNTCALTVNMLEESDAGDYTCIATNV 5295
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS C++ + ++E PP F Q + V G + + ++G+ P + W K E+
Sbjct: 5296 AGSDECSAPLTVRE---PPSFVQKPEAMDVLTGANVTFTSIIKGTPPFTVSWFKGSSELA 5352
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
P DRC+ S + A LE V +GDY C SN AG + + +
Sbjct: 5353 PGDRCNVSLEDCVAELELFGVDTTQSGDYTCIVSNEAGKASCTTHL-------------- 5398
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V FV + + G P +V W K + R I
Sbjct: 5399 -YVKAPAKFVKRLNDYSIEKGKPLILEGTYTGTPPISVTWKK-NGINITPSQRCNITTTE 5456
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A LEI +T D+G Y C N G+ + + + E
Sbjct: 5457 KSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILE 5495
Score = 295 bits (754), Expect = 1e-79
Identities = 176/590 (29%), Positives = 281/590 (47%), Gaps = 1/590 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKL-RPTATYKMHFRNNVATLVFNQVDSNDS 182
+ VG+ LQ + G I V W+K ++ R + + + NVATL F + ++ ++
Sbjct: 5037 ISTIVGEEVQLQTTIEGPEPISVVWFKDKGEIVRESDNIWVSYSENVATLQFARAETANA 5096
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y C+ +N G L+V E P + + ++ T G EC V+G+ +S
Sbjct: 5097 GKYTCQIKNDAGMQECFATLSVLE---PAAIVEKPESIRVTTGDTCTLECTVTGTPELST 5153
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WFKDG+ L + SF + V+ L I S +G YS NP+G S +A + +++
Sbjct: 5154 KWFKDGKELTSDSKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASVQVSD 5213
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F L + G S EC V G+ PI V+W + E+ SG YQ + +N+
Sbjct: 5214 RIVPPSFTRKLKETHGLSGSSVVMECKVYGSPPISVSWFHEGNEVSSGRKYQTTLTDNTC 5273
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
LT+ +++ D G YTC A N G D C+A L ++E PPSF +K E ++ G +
Sbjct: 5274 ALTVNMLEESDAGDYTCIATNVAGSDECSAPLTVRE---PPSFVQK-PEAMDVLTGANVT 5329
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
+ G+ P +V+W+K + E+ P C ++ ++ L++ +G YTC VSN+A
Sbjct: 5330 FTSIIKGTPPFTVSWFKGSSELAPGDRCNVSLEDCVAELELFGVDTTQSGDYTCIVSNEA 5389
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G A CT+ + +K P K F + L ++ +G+ L L G+ PI + W K G I P
Sbjct: 5390 GKASCTTHLYVKAPAK---FVKRLNDYSIEKGKPLILEGTYTGTPPISVTWKKNGINITP 5446
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S RC+ + +A+LE T DAG Y C N +G D+ +++
Sbjct: 5447 SQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPP--------- 5497
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+FV + + ++V +A+ ++ G P V W KG +L +H + +
Sbjct: 5498 ------YFVKQLEPVKVTVGDSASLQCQIAGTPEIGVSWYKGD-TKLRPTATYKMHFRNN 5550
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLR 1772
A L DSG Y C A N GE+ S+ L V E+K LR
Sbjct: 5551 VATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLSVQEQKLPPSFSRQLR 5600
Score = 291 bits (745), Expect = 2e-78
Identities = 177/566 (31%), Positives = 270/566 (47%), Gaps = 1/566 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V + S + Q +AG+P I ++W K D L + F NNVATL VD+ SG
Sbjct: 2534 VTTVLKSSGTFQSTVAGSPPISITWLKDDHILEEDDNVHISFVNNVATLQIRAVDNGHSG 2593
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C+A+N G FL VQE P + + V T PV EC V+G+ + V
Sbjct: 2594 RYTCQAKNESGVERCYAFLLVQE---PAQILEKAKSVDVTEKDPVTLECVVAGTPELKVK 2650
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W KDG+ + SF +NVA+ I + +GQY+ N GS+S A L + +
Sbjct: 2651 WLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQ 2710
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F L +D ++G S EC V+G+ PI W KD +E+ + Y++ EN+
Sbjct: 2711 DIPPSFTKKLTKMDKILGSSIRMECKVSGSLPISAQWFKDGKEVSTSAKYRLVCHENTVS 2770
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + ++ DT YTC N G D+C+ L +KE PPSF K E + ++
Sbjct: 2771 LEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE---PPSFLVK-PERQQAIPDSTVEF 2826
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+ + G+ P + W+K++VE+ C I + + L + G YTC+V+ND G
Sbjct: 2827 KAVLKGTPPFKIKWFKDDVELASGPTCFIGLEGSTSFLNLYSVDASKTGQYTCQVTNDVG 2886
Query: 1086 SALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
S CT+ +++ E PP F + L V G+ +L C + GS IR+ W + E++
Sbjct: 2887 SDSCTTMLLVTE---PPKFVKKLEASKIVKAGDSARLECKITGSPEIRVVWYRNEHELQA 2943
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
SD+ +F + AVL+ ++ D+GD++C+A N AGS + +KV
Sbjct: 2944 SDKYRMTFIDSVAVLQMNNLGTEDSGDFICEAQNPAGSTSCSTKV--------------- 2988
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
V F S P + ++ T + ++ G P V W K K RQL + I K
Sbjct: 2989 IVKEPPVFSSFPPVVETLKNTEVSLECELSGTPPFEVIWYKDK-RQLRSSKKYKIASKNF 3047
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHG 1700
A + I + +D G Y C A N+ G
Sbjct: 3048 HASIHILNVETSDIGEYHCKAQNEVG 3073
Score = 291 bits (744), Expect = 2e-78
Identities = 192/606 (31%), Positives = 274/606 (45%), Gaps = 30/606 (4%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
+G S L+C++AG+ I V+W+ TK+ A Y+ F +NV TL N +DS+D G Y C
Sbjct: 3290 LGTSCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGSYTC 3349
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKD 377
A N+ G L VQE PPSF ++ ++ G V F + G+ P V WF+
Sbjct: 3350 VAANAAGSDECRAALAVQE---PPSFVKEPEPLEILPGKNVTFTSVIRGTPPFKVGWFRG 3406
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL--------- 530
R L G F D VA L +F D S +G+Y+C +N G S + RL
Sbjct: 3407 ARELVRGDQCNIYFEDTVAELELFNVDISQSGEYTCVVSNNAGQTSCTTRLFVKGLLACI 3466
Query: 531 -------------------ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVA 653
+L P F L+ G+S E TGT PI V
Sbjct: 3467 CSSDFLYAAIYVLFLGLIAVLCHSPEPATFVKKLSDHSVEPGKSIILESTYTGTLPIAVT 3526
Query: 654 WAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLN--IK 827
W KD I I E + L IL K D GQY+C NE GKD C A L I
Sbjct: 3527 WKKDGFNISQSERCSIVTTEKTCILEILNSTKKDAGQYSCEIENEAGKDVCKALLLNVIL 3586
Query: 828 ERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNN 1007
L PP F +L E +E + G+S L+ +VAG+ I+V+WYK + ++ PT F NN
Sbjct: 3587 SSLEPPYFVTEL-EPLEASVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNN 3645
Query: 1008 ALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFL 1187
L K ++ D+G YTCK N G+A + I+E + PP F + L + + G +
Sbjct: 3646 VATLVFNKVNINDSGEYTCKAENSIGTAASKTVFRIQERQLPPSFARQLKDIEQTVGLPV 3705
Query: 1188 QLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNV 1367
L+C + GS PI++ W + G ++ + SF + A L+ + +G Y C ASN
Sbjct: 3706 TLTCRLNGSAPIQVCWYRDGVLLRDDENLQMSFVDNVATLKILQTDLSHSGQYSCSASNP 3765
Query: 1368 AGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIP 1547
G+ +S +++ FF +P SI V+ +A F V G
Sbjct: 3766 LGTASSSARLAVREPKKSP------------FFDIKPVSIDVIAGESADFECHVTGAQPM 3813
Query: 1548 NVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
+ W+K +++ GG I G+ L I K DSG Y C A N G+ + L
Sbjct: 3814 RITWSKDN-KEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLS 3872
Query: 1728 VNERKK 1745
V E K
Sbjct: 3873 VKEPPK 3878
Score = 289 bits (740), Expect = 6e-78
Identities = 188/609 (30%), Positives = 282/609 (46%), Gaps = 10/609 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ VT GD A+LQ + +GT EI W+K +L YK+ + V+ L + DSG
Sbjct: 2065 IDVTQGDPATLQVKFSGTKEITARWFKDGQELTLGQKYKISVTDTVSILKIISTEKRDSG 2124
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY +N VG S + V + +PPSF+++L+ + G + EC V+GS PIS+
Sbjct: 2125 EYTFEVQNDVGRSSCKASINVLDLIIPPSFTKRLKKMDSIKGSSIDLECIVAGSHPISIQ 2184
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKD + + + SF DN A L I + S +G Y+C+ATN G S L + E
Sbjct: 2185 WFKDDQEISASEKYKFSFHDNTAFLEISHLEGSDSGTYTCSATNKAGHNQCSGHLTVKE- 2243
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP+F D + V GT P+ + W KDN+E+ SG + + S
Sbjct: 2244 --PPYFVEKPQSQDVNPSTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTI 2301
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + D+G Y C N+VG + A L +KE PP F KK S + G S
Sbjct: 2302 LELFSAKSADSGTYICQLSNDVGTATSKATLFVKE---PPQFIKKPSPVLVLRNGQSTTF 2358
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ G+ I V+WY + EI I+F + Q+ A + ++G Y C+ NDAG
Sbjct: 2359 ECQITGTPEIRVSWYLDGNEITAIKKHGISFIDGLATFQISGARVENSGTYVCEARNDAG 2418
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
+A C+ + +KE PP F + L PV V + +QL C V G+ P + WL+ +EI+ S
Sbjct: 2419 TASCSIELKVKE---PPTFIRELKPVEVVKDSDVQLECEVAGTAPFEVTWLRNNKEIRSS 2475
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + + L +D GDY C SN GS +S +KV+
Sbjct: 2476 KKYTLTDRVSVFSLHITKCDPSDTGDYQCIVSNEGGSCSSSTKVSLKEPPS--------- 2526
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
F+ + +++ V K++ TF + V G P ++ W K L + + I +
Sbjct: 2527 ------FIKKIENVTTVLKSSGTFQSTVAGSPPISITWLKDD-HILEEDDNVHISFVNNV 2579
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNL------QVNERKKQ----EKIEGDLRA 1775
A L+IR SG Y C A N+ G L Q+ E+ K EK L
Sbjct: 2580 ATLQIRAVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQILEKAKSVDVTEKDPVTLEC 2639
Query: 1776 MLKKTPVLK 1802
++ TP LK
Sbjct: 2640 VVAGTPELK 2648
Score = 288 bits (738), Expect = 1e-77
Identities = 177/574 (30%), Positives = 280/574 (48%), Gaps = 1/574 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V GDSA L+C++ G+PEI V WY+ + +L+ + Y+M F ++VA L N + + DSG++
Sbjct: 2912 VKAGDSARLECKITGSPEIRVVWYRNEHELQASDKYRMTFIDSVAVLQMNNLGTEDSGDF 2971
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
IC A+N G S ST + V+E PP FS V+ V EC +SG+ P V W+
Sbjct: 2972 ICEAQNPAGSTSCSTKVIVKE---PPVFSSFPPVVETLKNTEVSLECELSGTPPFEVIWY 3028
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KD R L+ + + + A+++I + S G+Y C A N +GS + + L E
Sbjct: 3029 KDKRQLRSSKKYKIASKNFHASIHILNVETSDIGEYHCKAQNEVGSDTCICTVKLKE--- 3085
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE-IRSGGNYQISYLENSAHL 728
PP F L + V GE A+ + ++ G QPI V W K+ E IR N +I+++EN A L
Sbjct: 3086 PPRFVSKLNSLTVVAGEPAELQAYIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATL 3145
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
K + + G+Y C N+ G A L + E P+ + + + T G + LE
Sbjct: 3146 QFAKAEPANAGKYICQIKNDGGMRENMATLTVLE----PAVIVEKAGPMTVTVGETCTLE 3201
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+VAG+ +SV WYK+ + + + +F N L++ DAG YT +V N+ G
Sbjct: 3202 CKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISTLKILSVERQDAGTYTFQVQNNVGK 3261
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
+ CT+ + + + PP F + L G L C V GS PI + W +I
Sbjct: 3262 SSCTAVVDVSDRMVPPSFTRRLRDTVGVLGTSCILECKVAGSSPISVAWFHEKTKIVSGA 3321
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ +F++ L+ + +D G Y C A+N AGSD ++ + V
Sbjct: 3322 KYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANAAGSDECRAALA---------------V 3366
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
FV EP+ + ++ TF + + G P V W +G R+L +G + I+ + A
Sbjct: 3367 QEPPSFVKEPEPLEILPGKNVTFTSVIRGTPPFKVGWFRGA-RELVRGDQCNIYFEDTVA 3425
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+LE+ + + SG Y CV N G+ L V
Sbjct: 3426 ELELFNVDISQSGEYTCVVSNNAGQTSCTTRLFV 3459
Score = 288 bits (737), Expect = 1e-77
Identities = 179/577 (31%), Positives = 276/577 (47%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+VT GD A+L+ + GTPE+ WYK L + Y++ F+NNVA L F + +DSG
Sbjct: 1503 VQVTAGDPATLEYTVTGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSG 1562
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y N VG S T TV ++ + P F++ LR+V VG +C ++GS P+ V+
Sbjct: 1563 QYTFEVSNEVGSSSCETTFTVLDRDIAPFFTKPLRNVASVVGSACRLDCRIAGSLPMRVA 1622
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKDGR L G + +F++ A+L I D S AG ++C ATN +GS SS L++ E
Sbjct: 1623 WFKDGRELASGDKYRAAFVEGTASLEIHGVDLSDAGTFTCRATNSVGSKDSSGALVVQE- 1681
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F A D + G + + G+ P V W K RE+ SGG+ I+ + +
Sbjct: 1682 --PPSFVTKPASKDVLPGSAVCLKSTFRGSGPFTVRWLKGGRELVSGGSCYITKEASESS 1739
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + V D+G YTC N G C+A L +KE P +F +KL + +G+S +L
Sbjct: 1740 LELYVVKTSDSGTYTCQVGNAAGSVECSANLFVKE---PATFIEKLEPSQLLKKGDSTQL 1796
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+VAG+ PI + W+ N+ E+ ++F + +L + + + D+G Y C+ N+AG
Sbjct: 1797 ACKVAGTPPIKITWFANDRELKEGGRHRMSFVESTAVLSLTEVTTEDSGEYMCEAQNEAG 1856
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
S C S +++KE P F + PV V + + L V G+ P I W K ++
Sbjct: 1857 SDHCGSILIVKE---SPYFTKEFKPVEVLKEYDVMLLAEVAGTPPFDITWFKDNTTLRSG 1913
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + L+ DAG+Y C+ +N GS T ++VT
Sbjct: 1914 RKYKTFIQDQLVSLQILKFVATDAGEYQCRVTNEVGSSTCSARVTLREPPS--------- 1964
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FV + +S + TA F A + G V W K ++ + I + + +
Sbjct: 1965 ------FVKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDN-DEITEDDNIRMTFENNV 2017
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L + G Y C A N G + L V E
Sbjct: 2018 ASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE 2054
Score = 288 bits (736), Expect = 2e-77
Identities = 176/566 (31%), Positives = 278/566 (49%), Gaps = 3/566 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G S L+ GT I V+W K + + + L D+G+Y
Sbjct: 3505 VEPGKSIILESTYTGTLPIAVTWKKDGFNISQSERCSIVTTEKTCILEILNSTKKDAGQY 3564
Query: 192 ICRAENSVG-EVSSSTFLTVQEQKL-PPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
C EN G +V + L V L PP F +L ++ +VG V +C V+G+ I+VS
Sbjct: 3565 SCEIENEAGKDVCKALLLNVILSSLEPPYFVTELEPLEASVGDSVSLQCQVAGTPEITVS 3624
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+K L+ P +T F +NVATL + + + +G+Y+C A N IG+A+S + E
Sbjct: 3625 WYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTAASKTVFRIQER 3684
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
+ PP F L ++ VG C + G+ PI+V W +D +R N Q+S+++N A
Sbjct: 3685 QLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQMSFVDNVAT 3744
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L IL+ D +GQY+C A N +G S +A+L ++E P F K +++ G S
Sbjct: 3745 LKILQTDLSHSGQYSCSASNPLGTASSSARLAVREPKKSPFFDIK-PVSIDVIAGESADF 3803
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E V G+QP+ + W K+N EI P N IT N L++ K GD+G YTC+ +ND G
Sbjct: 3804 ECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVG 3863
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSE-GEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
+C++ + +KE PP F + L V++ GE +QL C + GS I++QW + E+
Sbjct: 3864 KDMCSAQLSVKE---PPKFVKKLEASQVAKHGESIQLECKISGSPEIKVQWFRNDSELHE 3920
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + SF N A+L + + D+GDY+C+A N G + + +T
Sbjct: 3921 SWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALT-------------- 3966
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
V F +P + ++ + F ++ G P V W K + +Q+ + I K
Sbjct: 3967 -VKAPPVFTQKPSPVGALKGSDVIFQCEISGTPPFEVVWVKDR-KQVRSSKKFKITSKNF 4024
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHG 1700
+ L I + +D G Y C A N+ G
Sbjct: 4025 DTSLHILNLEASDVGEYHCKATNEVG 4050
Score = 284 bits (726), Expect = 3e-76
Identities = 177/581 (30%), Positives = 285/581 (49%), Gaps = 3/581 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+V L ++AGTP ++W+K +T LR YK ++ + +L + + D+
Sbjct: 1878 PVEVLKEYDVMLLAEVAGTPPFDITWFKDNTTLRSGRKYKTFIQDQLVSLQILKFVATDA 1937
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY CR N VG + S +T++E PPSF +++ G F+ + GS PI+V
Sbjct: 1938 GEYQCRVTNEVGSSTCSARVTLRE---PPSFVKKIESTSSLRGGTAAFQATLKGSLPITV 1994
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD + + NI+ +F +NVA+L + + G+Y C A N G SA L + E
Sbjct: 1995 TWLKDNDEITEDDNIRMTFENNVASLKASMGDAGLYTCKVSND 1079
+++G +AWYK+ I + F ++ L++ D G+YT SN
Sbjct: 1307 FHCKMSGYPLPKIAWYKDGKRIKHGERYHMDFLQDGRASLRIPVVLPEDEGIYTAFASNM 1366
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQ-------W 1235
G+A+C+ + + EP P ++ TP VS +S PIR+
Sbjct: 1367 KGNAICSGKLYV-EPAAPLSAPTYIPTPEPVS--RIRSISPRSVSRSPIRMSPARMSPAR 1423
Query: 1236 LKAGREIKPSDR---------------CSFSFANG-TAVLEFKDV--------------- 1322
+ GR ++ +D SF G TA + K V
Sbjct: 1424 MSPGRRLEETDESQLERLYKPVFVLKPTSFKCVEGQTARFDLKVVGRPMPETFWFHDGQQ 1483
Query: 1323 ------------------------TKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
T +D+G++ A N AG + +T
Sbjct: 1484 IVNDYTHKVVVKEDGTQSLLIVPATPSDSGEWTVVAQNRAGKSSISVILTVEAVEHQV-- 1541
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQL-NQGGRIFI 1607
K FV + +++ + E + + G+P P++ W K + ++ +I I
Sbjct: 1542 --------KPVFVEKLRNLNIKEGSRLEMKVRATGNPNPDIVWLKNSEIIVPHKYPKIRI 1593
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG----EIESNVNLQVNERKKQEKI---EGD 1766
EA L+I T DS Y A NK G + NV ++ E + + ++ G
Sbjct: 1594 EGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERRLIIPRGT 1653
Query: 1767 LRAMLKKTPV-----LKKGAGEEEEIDIMELLKNVDP 1862
RA P L+ G + EE D+ + K P
Sbjct: 1654 YRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1690
Score = 104 bits (260), Expect = 3e-22
Identities = 134/565 (23%), Positives = 224/565 (39%), Gaps = 3/565 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G A L+C+++ V WY D +++P + LV N+ ++D G
Sbjct: 2441 VNVLEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVHAIVKGTKQRLVINRTHASDEG 2500
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y + VG V +S L+V++ K+ R LRD+ T VV E +S S I V
Sbjct: 2501 PY----KLVVGRVETSCDLSVEKIKI----IRGLRDLTCTETQNVVLEVELSHS-GIDVL 2551
Query: 366 W-FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W FKD + +K + + L + + G+Y+ A G +S +L +
Sbjct: 2552 WNFKD-KEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGEYTFYA----GENRTSGKLTVAG 2606
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
G PL + A FEC V + W KD + + +
Sbjct: 2607 GA----ISKPLTDQTVAESQEAVFECEVANPDS-EGEWLKDGKHLPLSKTIRSESDGRKR 2661
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I D G+YT +V +A+L ++ I + K L TV ET+ F
Sbjct: 2662 RLIIAATKLDDIGEYT----YKVATSKTSAKLKVEAVKIKKTL-KNL--TVTETQDAVFT 2714
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
+E + V W +N V + + ++ K L++K ++ D +Y K+
Sbjct: 2715 VE--LTHPNVKGVQWIRNGVVLESSDKYTVSVKGTVYSLRIKNCAVADESVYGFKLGKLG 2772
Query: 1083 GSA-LCTSSI-VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
SA L ++ +IK+PK VT E + V + + ++W EI
Sbjct: 2773 ASARLHVETVKIIKKPK----------DVTALENATVSFEVSV-SHDTVPVKWFHKNVEI 2821
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
KPSD+ L + ++ +DAG+Y V G K+K+
Sbjct: 2822 KPSDKHRLVSERKVHKLMLQHISPSDAGEYTA----VVGQLECKAKLFVE---------- 2867
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
L ++I V E TA+F +V +P++ G ++++ +I + +
Sbjct: 2868 ------TLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVV--Q 2919
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFN 1691
G +L I +T+ DS Y V N
Sbjct: 2920 GKLHQLIIMNTSTEDSAEYTFVCGN 2944
Score = 99.8 bits (247), Expect = 8e-21
Identities = 140/563 (24%), Positives = 229/563 (40%), Gaps = 5/563 (0%)
Frame = +3
Query: 24 DSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRA 203
+SAS +++ G KG+ LRP+ T ++ + L + V + +GE + +A
Sbjct: 11429 ESASFDAEISEVDVPGQWKLKGEL-LRPSPTCEIKAEDGKRFLTLHNVKLDQAGEVLYQA 11487
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGR 383
N+V ++ LTV+E +L F+ L+DV FEC ++ +V W K
Sbjct: 11488 LNAV----TTAILTVKEIEL--DFAVPLKDVTVPEKRQARFECVLT--REANVIWSKGPD 11539
Query: 384 PLK--DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
+K D +I T ++ +N Q D G Y T + +SARL +T R
Sbjct: 11540 IIKSSDKFDIITDGKKHILVINNSQFDDE--GVY----TAEVEGKKTSARLFVTGIRLK- 11592
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F PL GE+A F C ++ + + V W K++ ++ + IS + L +
Sbjct: 11593 -FISPLEDQTVKEGETATFVCELSH-EKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMR 11650
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET--VEETEGNSFRLEG 911
+V D Q +V S TA L + E P FT KL + VE+ E +
Sbjct: 11651 EVTMDDISQIKA----QVKDLSSTANLKVIEA--DPYFTVKLHDKTGVEKDE-----IVL 11699
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
R S+ + V W+K+ E+ P+ I +L++KKA + D G Y C D A
Sbjct: 11700 RCEVSKDVPVKWFKDGEELLPSPKHSIKADGLRRILKIKKADLKDKGEYVCDCGTDTTKA 11759
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEP-IRIQWLKAGREIKPSD 1268
T + + +KP L V V GE + + SEP + QW G + S
Sbjct: 11760 NVTVEARLIKVEKP------LYGVEVFVGETARFEIEL--SEPDVHGQWKLKGEPLTASP 11811
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
C +L + G +A+N + K K
Sbjct: 11812 DCEIIEDGKKHILVLYNCRLDMTGKVSFQAANAKSAANLKVK------------------ 11853
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
+ L F++ ++V EK A F +V +P +W KG +++ RI + + G +
Sbjct: 11854 ELPLIFITPLSDVKVFEKDEAKFECEVSREP-KTYRWLKGT-QEITGDDRIELIKDGTKH 11911
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKH 1697
L I+ D Y A ++H
Sbjct: 11912 SLVIKSAAFEDEAKYIFEAEDQH 11934
Score = 99.4 bits (246), Expect = 1e-20
Identities = 151/611 (24%), Positives = 242/611 (39%), Gaps = 8/611 (1%)
Frame = +3
Query: 15 TVGDS--ASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
TV +S A +C++A P+ W K L + T + L+ +D GE
Sbjct: 2617 TVAESQEAVFECEVAN-PDSEGEWLKDGKHLPLSKTIRSESDGRKRRLIIAATKLDDIGE 2675
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y + S +S L V+ K+ + L+++ T VF ++ V W
Sbjct: 2676 YTYKVATS----KTSAKLKVEAVKI----KKTLKNLTVTETQDAVFTVELTHPNVKGVQW 2727
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
++G L+ S V +L I + Y +G +SARL + +
Sbjct: 2728 IRNGVVLESSDKYTVSVKGTVYSLRIKNCAVADESVYGFK----LGKLGASARLHVETVK 2783
Query: 549 NPPFFDIPLAPVDAVVGESA--DFECHVT-GTQPIKVAWAKDNREIRSGGNYQISYLENS 719
I P D E+A FE V+ T P+K W N EI+ +++
Sbjct: 2784 ------IIKKPKDVTALENATVSFEVSVSHDTVPVK--WFHKNVEIKPSDKHRLVSERKV 2835
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET-VEETEGNS 896
L + + D G+YT VG+ C A+L ++ I TK + V ET+ S
Sbjct: 2836 HKLMLQHISPSDAGEYTAV----VGQLECKAKLFVETLHI----TKTMKNIEVPETKTAS 2887
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
F E + W KN VEI + +I + L + S D+ YT N
Sbjct: 2888 FECE---VSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 2944
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
D SA + P + L + E + + V E I +WLK G EI
Sbjct: 2945 DQVSATLKVT--------PIMITSMLKDINAEEKDTITFEVTVN-YEGISYKWLKNGVEI 2995
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
K +DRC T L ++V DA +Y + VAG TS + +
Sbjct: 2996 KSTDRCQMRTKKLTHSLNIRNVHFGDAAEY----TFVAGKATSTATL------------- 3038
Query: 1437 XXXVDGK-LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
V+ + + F + I+V+EK A F +V +P V+W K ++L RI I +
Sbjct: 3039 --YVEARHIEFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMK-DGQELQLVDRIKIQK 3094
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK-KQEKIEGDLRAMLKKT 1790
+ +L I T +D+G Y VA G S+ NL V R + I+ +++ + K+
Sbjct: 3095 EKYVHRLLIPSTRMSDAGKYTVVA----GGNMSSANLFVEGRDVRIRSIKREVQVIEKQR 3150
Query: 1791 PVLKKGAGEEE 1823
V++ E++
Sbjct: 3151 AVVEFEVNEDD 3161
Score = 98.2 bits (243), Expect = 2e-20
Identities = 81/303 (26%), Positives = 126/303 (41%), Gaps = 36/303 (11%)
Frame = +3
Query: 318 VVFECAVSG-SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTAT 494
V + C + + V+W+ R L++ + ++ D VAT+ + + G Y C
Sbjct: 31602 VKYVCRIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVATMYVKDITKFDDGTYRCKVV 31661
Query: 495 NPIGSASSSARLILTEGRN-------------------------PPFFDIPLAPVDAVVG 599
N G SS A L + R PP F +PL A VG
Sbjct: 31662 NDYGEDSSYAELFVKGVREVYDYYCRRTVKKLKRRTDAMRLLERPPEFTLPLYNKTAYVG 31721
Query: 600 ESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA---HLTILKVDKGDTGQYT 770
E+ F +T +V W K ++I+ G + + E+ LTI V D +YT
Sbjct: 31722 ENVRFGVTITVHPEPRVTWYKSGQKIKPGDDDRKYIFESDKGLYQLTINSVTMDDDAEYT 31781
Query: 771 CYAVNEVGKDSCTAQLNIKERLIPPSFT------KKLSETVEETEGNSFRLEGRVAGSQP 932
A N+ G+DSC A+L + PPS T K+L E EG S E RV+G P
Sbjct: 31782 VVARNKYGEDSCKAKLTVTPHP-PPSDTTLRPMFKRLLANAECQEGQSVCFEIRVSGIPP 31840
Query: 933 ISVAWYKNNVEIHPTANCEITFKN-NALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSI 1109
++ W K+ + N EI + + L ++ D G Y +N AGS+ C + +
Sbjct: 31841 PTLKWEKDGRPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSSSCQAHL 31900
Query: 1110 VIK 1118
++
Sbjct: 31901 QVE 31903
Score = 97.4 bits (241), Expect = 4e-20
Identities = 134/575 (23%), Positives = 217/575 (37%), Gaps = 3/575 (0%)
Frame = +3
Query: 3 PVK-VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSND 179
P+K VTV + + + T E V W KG ++ + + + LV N +D
Sbjct: 11508 PLKDVTVPEKRQARFECVLTREANVIWSKGPDIIKSSDKFDIITDGKKHILVINNSQFDD 11567
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
G Y E + S+ F+T K F L D G F C +S E +
Sbjct: 11568 EGVYTAEVEGK--KTSARLFVTGIRLK----FISPLEDQTVKEGETATFVCELS-HEKMH 11620
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V WFK+ L + S L + + Q + SS+A L +
Sbjct: 11621 VVWFKNDAKLHTSRTVLISSEGKTHKLEMREVTMDDISQIKA----QVKDLSSTANLKVI 11676
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E P+F + L V + C V+ P+K W KD E+ + I
Sbjct: 11677 EA--DPYFTVKLHDKTGVEKDEIVLRCEVSKDVPVK--WFKDGEELLPSPKHSIKADGLR 11732
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I K D D G+Y C + G D+ A + ++ RLI +K VE G +
Sbjct: 11733 RILKIKKADLKDKGEYVC----DCGTDTTKANVTVEARLIK---VEKPLYGVEVFVGETA 11785
Query: 900 RLEGRVAGSQP-ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
R E + S+P + W + + +CEI +L + + G KVS
Sbjct: 11786 RFE--IELSEPDVHGQWKLKGEPLTASPDCEIIEDGKKHILVLYNCRLDMTG----KVSF 11839
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
A +A +++ +KE P +F L+ V V E + + C V EP +WLK +EI
Sbjct: 11840 QAANAKSAANLKVKE--LPLIFITPLSDVKVFEKDEAKFECEV-SREPKTYRWLKGTQEI 11896
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
DR L K D Y+ +A + TS +
Sbjct: 11897 TGDDRIELIKDGTKHSLVIKSAAFEDEAKYIFEAED---QHTSGKLI------------- 11940
Query: 1437 XXXVDG-KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
++G +L F++ + + E+ +A F ++ D I V+W K R L+ + +
Sbjct: 11941 ---IEGIRLKFLTPLKDVTAKERESAVFTVELSHDNI-RVRWFKNDQR-LHTSKFVSMDD 11995
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNV 1718
+G + R+ + D+ + A E + V
Sbjct: 11996 EGKTHSITFRNLSIDDTSQIKVEAMGLSSEAKLTV 12030
Score = 96.7 bits (239), Expect = 7e-20
Identities = 88/308 (28%), Positives = 129/308 (41%), Gaps = 36/308 (11%)
Frame = +3
Query: 72 VSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVSSSTFL--- 242
V+WY G +L + Y++ + + VAT+ + D G Y C+ N GE SS L
Sbjct: 31617 VTWYFGVRQLENSEKYEITYEDGVATMYVKDITKFDDGTYRCKVVNDYGEDSSYAELFVK 31676
Query: 243 ------------TVQEQK----------LPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
TV++ K PP F+ L + VG V F ++
Sbjct: 31677 GVREVYDYYCRRTVKKLKRRTDAMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEP 31736
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDN---VATLNIFQTDRSFAGQYSCTATNPIGSASSSAR 527
V+W+K G+ +K G + + ++ + L I +Y+ A N G S A+
Sbjct: 31737 RVTWYKSGQKIKPGDDDRKYIFESDKGLYQLTINSVTMDDDAEYTVVARNKYGEDSCKAK 31796
Query: 528 LILTEGRNP------PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGG 689
L +T P P F LA + G+S FE V+G P + W KD R + G
Sbjct: 31797 LTVTPHPPPSDTTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGRPLSLGP 31856
Query: 690 NYQISY--LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKL 863
N +I + L+ A L I DTG Y A N G SC A L + ERL + K+
Sbjct: 31857 NIEIIHEGLDYYA-LHIRDTLPEDTGYYRVTATNTAGSSSCQAHLQV-ERL---RYVKQE 31911
Query: 864 SETVEETE 887
+T EE E
Sbjct: 31912 FKTKEEHE 31919
Score = 95.5 bits (236), Expect = 2e-19
Identities = 140/580 (24%), Positives = 225/580 (38%), Gaps = 6/580 (1%)
Frame = +3
Query: 15 TVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYI 194
+VG SA +C ++ + + SW K + +R + ++ L V +D+GEY
Sbjct: 11148 SVGSSAIFECLVSPSTAV-TSWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYT 11206
Query: 195 CRAENSVGEVSSSTFLTVQEQKLPPSFSRQL-RDVQETVGLPVVFECAVSGSEPISVSWF 371
C E +S+ L V+E LP F + L +V G P+ C ++ V W
Sbjct: 11207 CVLRLGNKEKTSTAKLIVEE--LPVRFVKTLEEEVTVVKGQPLYLSCELNKER--DVVWR 11262
Query: 372 KDGRPLKDGP-NIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
KDG+ + + P I + + L I D S AG Y+ T N SS ++ R
Sbjct: 11263 KDGKIVVEKPGKIVPGVIGLLRALTINDADDSDAGTYTVTVENANNLECSSCVKVVEVIR 11322
Query: 549 N---PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
+ P D + P V F C + P + W K EI + + +
Sbjct: 11323 DWLVKPIRDQHVKPKGTAV-----FTCVIAKDTP-NIKWYKGYDEIPWEPTDKTEIIRDG 11376
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE-TVEETEGNS 896
H+ LKV YAV GK A+L + ER + K + + T+ E E S
Sbjct: 11377 NHIH-LKVKNAMPEDIDEYAVEIEGK-RYPAKLTLGEREV--ELLKPIEDVTIYEKESAS 11432
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
F E + W + P+ CEI ++ L + + AG +V
Sbjct: 11433 FDAE---ISEVDVPGQWKLKGELLRPSPTCEIKAEDGKRFLTLHNVKLDQAG----EVLY 11485
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
A +A+ T+ + +KE + F L VTV E + C + + + W K I
Sbjct: 11486 QALNAVTTAILTVKEIELD--FAVPLKDVTVPEKRQARFECVL--TREANVIWSKGPDII 11541
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
K SD+ +L + D G Y + V G TS
Sbjct: 11542 KSSDKFDIITDGKKHILVINNSQFDDEGVY---TAEVEGKKTSARLFVTGI--------- 11589
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
+L F+S + V E TATF+ ++ + + +V W K +L+ + I +
Sbjct: 11590 ------RLKFISPLEDQTVKEGETATFVCELSHEKM-HVVWFKND-AKLHTSRTVLISSE 11641
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
G KLE+R+ T D + + ++ S NL+V E
Sbjct: 11642 GKTHKLEMREVTMDDISQIKA----QVKDLSSTANLKVIE 11677
Score = 95.1 bits (235), Expect = 2e-19
Identities = 88/324 (27%), Positives = 127/324 (39%), Gaps = 36/324 (11%)
Frame = +3
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS 1106
Q V WY ++ + EIT+++ + VK + D G Y CKV ND G +
Sbjct: 31613 QSTQVTWYFGVRQLENSEKYEITYEDGVATMYVKDITKFDDGTYRCKVVNDYGEDSSYAE 31672
Query: 1107 IVIKEPK-------------------------KPPVFDQHLTPVTVSEGEFLQLSCHVRG 1211
+ +K + +PP F L T GE ++ +
Sbjct: 31673 LFVKGVREVYDYYCRRTVKKLKRRTDAMRLLERPPEFTLPLYNKTAYVGENVRFGVTITV 31732
Query: 1212 SEPIRIQWLKAGREIKPSD---RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
R+ W K+G++IKP D + F G L VT D +Y A N G D+
Sbjct: 31733 HPEPRVTWYKSGQKIKPGDDDRKYIFESDKGLYQLTINSVTMDDDAEYTVVARNKYGEDS 31792
Query: 1383 SKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWT 1562
K+K+T +L +E Q E + F +V G P P +KW
Sbjct: 31793 CKAKLTVTPHPPPSDTTLRPMFK-RLLANAECQ-----EGQSVCFEIRVSGIPPPTLKWE 31846
Query: 1563 KGKWRQLNQGGRI-FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV--- 1730
K R L+ G I IH+ D L IRDT D+G YR A N G +LQV
Sbjct: 31847 KDG-RPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSSSCQAHLQVERL 31905
Query: 1731 ----NERKKQEKIEGDLRAMLKKT 1790
E K +E+ E ++ + KT
Sbjct: 31906 RYVKQEFKTKEEHERHVQRQIDKT 31929
Score = 89.7 bits (221), Expect = 8e-18
Identities = 115/484 (23%), Positives = 185/484 (38%), Gaps = 7/484 (1%)
Frame = +3
Query: 243 TVQEQKLPPSFSRQLRDV----QETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQ 410
T Q + +P F ++++D+ E+VG +FEC VS S ++ SW KDG +++ P +
Sbjct: 11124 TYQLKAVPLKFVKEIKDIVLTEAESVGSSAIFECLVSPSTAVT-SWMKDGSNIRESPKHR 11182
Query: 411 TSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDA 590
L+I S AG+Y+C +S+A+LI+ E F V
Sbjct: 11183 FIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEE-LPVRFVKTLEEEVTV 11241
Query: 591 VVGESADFECHVTGTQPIKVAWAKDNR-EIRSGGNYQISYLENSAHLTILKVDKGDTGQY 767
V G+ C + + V W KD + + G + LTI D D G Y
Sbjct: 11242 VKGQPLYLSCELNKER--DVVWRKDGKIVVEKPGKIVPGVIGLLRALTINDADDSDAGTY 11299
Query: 768 TCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAW 947
T V C++ + + E +I K + + + +G + + V ++ W
Sbjct: 11300 T-VTVENANNLECSSCVKVVE-VIRDWLVKPIRDQHVKPKGTA--VFTCVIAKDTPNIKW 11355
Query: 948 YKNNVEI--HPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKE 1121
YK EI PT EI N + L+VK A D Y ++ A T E
Sbjct: 11356 YKGYDEIPWEPTDKTEIIRDGNHIHLKVKNAMPEDIDEYAVEIEGKRYPAKLTLGEREVE 11415
Query: 1122 PKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTA 1301
KP + VT+ E E + + QW G ++PS C +G
Sbjct: 11416 LLKP------IEDVTIYEKESASFDAEI-SEVDVPGQWKLKGELLRPSPTCEIKAEDGKR 11468
Query: 1302 VLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQ 1481
L +V AG+ + +A N + K + +L F +
Sbjct: 11469 FLTLHNVKLDQAGEVLYQALNAVTTAILTVK------------------EIELDFAVPLK 11510
Query: 1482 SIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTD 1661
+ V EK A F + + NV W+KG + + I G + L I ++ D
Sbjct: 11511 DVTVPEKRQARFECVLTRE--ANVIWSKGP-DIIKSSDKFDIITDGKKHILVINNSQFDD 11567
Query: 1662 SGLY 1673
G+Y
Sbjct: 11568 EGVY 11571
Score = 88.6 bits (218), Expect = 2e-17
Identities = 66/182 (36%), Positives = 82/182 (45%), Gaps = 11/182 (6%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRP---TATYKMHFRNNVATLVFNQVDSNDSGE 188
VG++ + PE V+WYK K++P Y + L N V +D E
Sbjct: 31720 VGENVRFGVTITVHPEPRVTWYKSGQKIKPGDDDRKYIFESDKGLYQLTINSVTMDDDAE 31779
Query: 189 YICRAENSVGEVSSSTFLTV------QEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
Y A N GE S LTV + L P F R L + + G V FE VSG
Sbjct: 31780 YTVVARNKYGEDSCKAKLTVTPHPPPSDTTLRPMFKRLLANAECQEGQSVCFEIRVSGIP 31839
Query: 351 PISVSWFKDGRPLKDGPNIQT--SFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
P ++ W KDGRPL GPNI+ LD A L+I T G Y TATN GS+S A
Sbjct: 31840 PPTLKWEKDGRPLSLGPNIEIIHEGLDYYA-LHIRDTLPEDTGYYRVTATNTAGSSSCQA 31898
Query: 525 RL 530
L
Sbjct: 31899 HL 31900
Score = 88.2 bits (217), Expect = 2e-17
Identities = 99/440 (22%), Positives = 165/440 (37%), Gaps = 62/440 (14%)
Frame = +3
Query: 264 PPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLN 443
PP+ L++V G V EC +SG V+W+++ ++ + Q +F +A L
Sbjct: 939 PPTLVSGLKNVTVIEGESVTLECHISGYPSPKVTWYREDYQIESSIDFQITFQSGIARLL 998
Query: 444 IFQTDRSFAGQYSCTATNPIGSASSS------------------ARLILTEGRN------ 551
I + +G+++CTA N G+ S+S A I TE +
Sbjct: 999 IREAFAEDSGRFTCTAVNEAGTVSTSCYLAVQVSEEFEKETTAVAEKITTEEKRFVESRD 1058
Query: 552 -------------------PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE 674
PFF V G S FEC V G V W K
Sbjct: 1059 VVMTDTSITEEHAGPGEPAAPFFITKPVVQKLVEGGSIVFECQVGGNPKPHVYWKKSGVP 1118
Query: 675 IRSGGNYQISYLENS--AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPS 848
+ SG Y++SY + + L I D G+YT N+ G+ S +A L E S
Sbjct: 1119 LTSGYRYKVSYNKQTGECRLVISMTFADDAGEYTIVIRNKHGETSASASL--LEEADYES 1176
Query: 849 FTKKLSETVEETEGNSFRLEGRVAGSQPISV-AWYKNNVEIHPTANCEITFKNNALLLQV 1025
K E + +T+ +F E +V P V + Y+ E + K+ ++
Sbjct: 1177 LMKSQQEMLYQTQVTAFVQEPKVGEIAPGYVYSEYEKEYEKEQALIRKKMAKDTVMVRTF 1236
Query: 1026 KKASMGDAGLYTCKVSNDAGSALCTSSI--VIKEPKKPPV-------------FDQHLTP 1160
+ + ++ + + +++ +++E + + FD +
Sbjct: 1237 VEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAIEAGFDLRVKN 1296
Query: 1161 VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSF-ANGTAVLEFKDVTKADA 1337
+ EG + C + G +I W K G+ IK +R F +G A L V D
Sbjct: 1297 YRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYHMDFLQDGRASLRIPVVLPEDE 1356
Query: 1338 GDYVCKASNVAGSDTSKSKV 1397
G Y ASN+ G+ K+
Sbjct: 1357 GIYTAFASNMKGNAICSGKL 1376
Score = 88.2 bits (217), Expect = 2e-17
Identities = 90/388 (23%), Positives = 150/388 (38%), Gaps = 17/388 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ +T G +L+ +AG + V W +L + Y+ + TL Q D G
Sbjct: 33076 MSITAGQKVTLKANIAGATD--VKWVLNGVELSNSDEYRYGISGSDQTLTIRQAGHKDEG 33133
Query: 186 EYICRAENSVGEVSSSTFLTV-QEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
C + S G + LT+ +E P+F Q R G V+F C +SG +
Sbjct: 33134 ILTCIGKTSQGIIKCQYDLTLSKELSDAPAFISQPRSQNVNEGQNVLFSCEISGEPSPEI 33193
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WFK+ P+ NI S NV +L I S +G+Y+ A N G S++A L +
Sbjct: 33194 EWFKNNLPISISSNISVSRSRNVYSLEIRNASVSDSGKYTIKAKNFHGQCSATASLTVL- 33252
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVT-GTQPIKVAWAKDNREIRSGGNYQISYLENS 719
P + P P + V+ S D + +Q ++++ +K S + S +
Sbjct: 33253 ----PLVEEP--PREVVLRTSGDTSLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEM 33306
Query: 720 --AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERL-------IPPSFTKKLSET 872
A ++ + + + +GK S T + R+ IPP + L
Sbjct: 33307 KFASMSAQSMSSMQESFVEMSSSSFMGKSSMTQLESSTSRMLKAGLRGIPPKI-EALPSD 33365
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNA------LLLQVKKA 1034
+ EG + G + W + IH N +++ V+K
Sbjct: 33366 ISIDEGKVLTVACAFTGEPTPEITWSRGGRTIHDQEQRGRFLMENTDDLTTLIIMDVRKQ 33425
Query: 1035 SMGDAGLYTCKVSNDAGSALCTSSIVIK 1118
D GLYT + N+ GS T +I I+
Sbjct: 33426 ---DGGLYTLSLGNEFGSDSATVNINIR 33450
Score = 79.3 bits (194), Expect = 1e-14
Identities = 52/180 (28%), Positives = 93/180 (51%), Gaps = 3/180 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATY---KMHFRNNVATLVFNQVDSN 176
V V G +A+ + ++G P VSW++ D ++ T+T ++ F + A L V
Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSWFR-DGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
+SG Y RA N G+ +S+ L V + PP+F+++L+ + G V + V+G
Sbjct: 74 NSGRYSLRATNGSGQATSTAELLVTAETAPPNFTQRLQSMTVRQGSQVRLQVRVTGIPTP 133
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
V +++DG ++ + Q S + +L I + +G YS ATN +G A+S+A L++
Sbjct: 134 VVKFYRDGAEIQSSLDFQISQEGELYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 79.3 bits (194), Expect = 1e-14
Identities = 73/288 (25%), Positives = 117/288 (40%), Gaps = 33/288 (11%)
Frame = +3
Query: 1113 IKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFAN 1292
++ P PP L VTV EGE + L CH+ G ++ W + +I+ S +F +
Sbjct: 933 VEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPKVTWYREDYQIESSIDFQITFQS 992
Query: 1293 GTAVLEFKDVTKADAGDYVCKASNVAGS------------------DTSKSKVTXXXXXX 1418
G A L ++ D+G + C A N AG+ T+ ++
Sbjct: 993 GIARLLIREAFAEDSGRFTCTAVNEAGTVSTSCYLAVQVSEEFEKETTAVAEKITTEEKR 1052
Query: 1419 XXXXXXXXXVDGKL-------------FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW 1559
D + FF+++P ++VE + F +VGG+P P+V W
Sbjct: 1053 FVESRDVVMTDTSITEEHAGPGEPAAPFFITKPVVQKLVEGGSIVFECQVGGNPKPHVYW 1112
Query: 1560 TKGKWRQLNQGGR--IFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
K L G R + +++ E +L I T D+G Y V NKHGE ++ +L
Sbjct: 1113 KK-SGVPLTSGYRYKVSYNKQTGECRLVISMTFADDAGEYTIVIRNKHGETSASASLL-- 1169
Query: 1734 ERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEIDIMELLKNVDPKEYEK 1877
E E + + ML +T V +E + E+ EYEK
Sbjct: 1170 EEADYESLMKSQQEMLYQTQV----TAFVQEPKVGEIAPGYVYSEYEK 1213
Score = 79.3 bits (194), Expect = 1e-14
Identities = 87/380 (22%), Positives = 147/380 (38%), Gaps = 19/380 (5%)
Frame = +3
Query: 303 TVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYS 482
T G V + ++G+ V W +G L + + + TL I Q G +
Sbjct: 33079 TAGQKVTLKANIAGAT--DVKWVLNGVELSNSDEYRYGISGSDQTLTIRQAGHKDEGILT 33136
Query: 483 CTATNPIGSASSSARLILTEGRN--PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAW 656
C G L L++ + P F P + + G++ F C ++G ++ W
Sbjct: 33137 CIGKTSQGIIKCQYDLTLSKELSDAPAFISQPRSQ-NVNEGQNVLFSCEISGEPSPEIEW 33195
Query: 657 AKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERL 836
K+N I N +S N L I D+G+YT A N G+ S TA L + +
Sbjct: 33196 FKNNLPISISSNISVSRSRNVYSLEIRNASVSDSGKYTIKAKNFHGQCSATASLTVLPLV 33255
Query: 837 IPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALL 1016
P E V T G++ L+G + SQ + ++ K ++ + + +
Sbjct: 33256 EEPP-----REVVLRTSGDT-SLQGSFS-SQSVQMSASKQEASFSSFSS-----SSASSM 33303
Query: 1017 LQVKKASMGDAGLYTCK---VSNDAGSALCTSSIVIKEPKK-----------PPVFDQHL 1154
++K ASM + + + V + S + SS+ E PP +
Sbjct: 33304 TEMKFASMSAQSMSSMQESFVEMSSSSFMGKSSMTQLESSTSRMLKAGLRGIPPKIEALP 33363
Query: 1155 TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD---RCSFSFANGTAVLEFKDVT 1325
+ +++ EG+ L ++C G I W + GR I + R + L DV
Sbjct: 33364 SDISIDEGKVLTVACAFTGEPTPEITWSRGGRTIHDQEQRGRFLMENTDDLTTLIIMDVR 33423
Query: 1326 KADAGDYVCKASNVAGSDTS 1385
K D G Y N GSD++
Sbjct: 33424 KQDGGLYTLSLGNEFGSDSA 33443
Score = 79.0 bits (193), Expect = 1e-14
Identities = 97/457 (21%), Positives = 175/457 (38%)
Frame = +3
Query: 30 ASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAEN 209
A+ +C+ + P + V WYK ++ Y+MH V L +D++D+ +Y C
Sbjct: 2179 ATFECETS-EPFVKVKWYKDGVEIHTGDKYRMHSDRKVHFLSVLMIDTSDAEDYSCVL-- 2235
Query: 210 SVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPL 389
V + + T + + F ++L+D++ EC ++ E I W+ G L
Sbjct: 2236 -VEDENVKTTAKLIVEGAVVEFVKELQDIEVPESFSGELECIIT-PENIEGKWYHKGVEL 2293
Query: 390 KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDI 569
K + L + + G+YS + ++ +L + P
Sbjct: 2294 KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFV----VDGKKTTCKLKMKP--RPIAILQ 2347
Query: 570 PLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDK 749
L+ G+ E V+ + ++ W KD E++ G I + S L I + K
Sbjct: 2348 GLSDQKVCEGDIVQLEVKVS-LENVEGVWMKDGEEVQPGDRVHIVIDKQSHMLLIEDMTK 2406
Query: 750 GDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQ 929
D G Y+ + + +G + +I P + V EG LE +V+
Sbjct: 2407 EDAGHYS-FTIPSLGLSTHGRVSVYSVDVITP------LKDVNVLEGTKAVLECKVSVPD 2459
Query: 930 PISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSI 1109
SV WY N+ +I P K L + + D G Y V G + +
Sbjct: 2460 VTSVKWYLNDEQIKPDDRVHAIVKGTKQRLVINRTHASDEGPYKLVV----GRVETSCDL 2515
Query: 1110 VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFA 1289
+++ K + L +T +E + + L + S I + W +EIKPS +
Sbjct: 2516 SVEKIK----IIRGLRDLTCTETQNVVLEVELSHS-GIDVLWNFKDKEIKPSSKYKIEAH 2570
Query: 1290 NGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
L ++ K D G+Y + AG + + K+T
Sbjct: 2571 GKIYKLTVLNMMKDDEGEY----TFYAGENRTSGKLT 2603
Score = 78.2 bits (191), Expect = 3e-14
Identities = 126/563 (22%), Positives = 206/563 (36%), Gaps = 48/563 (8%)
Frame = +3
Query: 186 EYICRAENSVG-------EVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSG 344
E+ AEN G +S T LT E P ++++DV +G C + G
Sbjct: 30519 EFRVFAENETGLSRPRRTAMSVKTKLTSGEA---PGVRKEMKDVTTKLGEAAQLSCQIVG 30575
Query: 345 SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
+ WF+ G+ L + S TL + ++ G Y+C ATN +G SS+
Sbjct: 30576 RPLPDIKWFRFGKELVQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCVATNEVGEVESSS 30635
Query: 525 RLILTEGRNPPFFDIPLAPVD----AVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
+L+L P F P P+ VG + G + W + + +++ N
Sbjct: 30636 KLLLQ--ATPQFH--PGYPLKEKYYGAVGSTLRIHVMYIGRPVPAITWFRGQKLLQNSEN 30691
Query: 693 YQISYLENSAHLTILKVD-KGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE 869
I E+ HL + V K G+Y N +G + I+++ P+ +
Sbjct: 30692 ITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVLGTVDTMLDVEIQDKPDKPTGPIVIEA 30751
Query: 870 TVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDA 1049
++ + S++ GS W N V CE K A V A
Sbjct: 30752 LLKNSVVISWKPPADDGGS------WITNYV----VEKCEA--KEGAEWQLVSSA----I 30795
Query: 1050 GLYTCKVSNDAGSA------------------LCTSSIVIKEPKKPPVFDQHLTPVTVSE 1175
+ TC++ N +A +S ++IK P + P T V++
Sbjct: 30796 SVTTCRIVNLTENAGYYFRVSAQNMFGISEPLEVSSVVIIKSPFEKPGAPGKPTITAVTK 30855
Query: 1176 GEFLQLSCHVR-------GSEPIRIQWLKAGREIKPSD----------RCSFSFANGTAV 1304
SC V G IR +L+ RE K + FS N
Sbjct: 30856 D-----SCVVAWKPPASDGGAKIRNYYLEK-REKKQNKWIAVTTDEIRETVFSVQNLIEG 30909
Query: 1305 LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS 1484
LE++ K + + S ++ T KS V F E ++
Sbjct: 30910 LEYEFRVKCENLGGESEWSEISEPVTPKSDVPIQAP----------------HFKEELRN 30953
Query: 1485 IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ-KGDEAKLEIRDTTKTD 1661
+ V ++ AT + KV G P P VKW + + G + I + KG +L I T D
Sbjct: 30954 LNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDD 31013
Query: 1662 SGLYRCVAFNKHGEIESNVNLQV 1730
+ +Y+ A N+ G + +L+V
Sbjct: 31014 ATVYQVRATNQGGSVSGTASLEV 31036
Score = 76.3 bits (186), Expect = 1e-13
Identities = 69/287 (24%), Positives = 110/287 (38%), Gaps = 35/287 (12%)
Frame = +3
Query: 636 QPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQ 815
Q +V W R++ + Y+I+Y + A + + + K D G Y C VN+ G+DS A+
Sbjct: 31613 QSTQVTWYFGVRQLENSEKYEITYEDGVATMYVKDITKFDDGTYRCKVVNDYGEDSSYAE 31672
Query: 816 LNIK-----------------------ERLI--PPSFTKKLSETVEETEGNSFRLEGRVA 920
L +K RL+ PP FT L G + R +
Sbjct: 31673 LFVKGVREVYDYYCRRTVKKLKRRTDAMRLLERPPEFTLPLYNKTAYV-GENVRFGVTIT 31731
Query: 921 GSQPISVAWYKNNVEIHP-TANCEITFKNNALLLQ--VKKASMGDAGLYTCKVSNDAGSA 1091
V WYK+ +I P + + F+++ L Q + +M D YT N G
Sbjct: 3YLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE 2054
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P +D G+ A + +GT+ I W KD +E+ G Y+IS + +
Sbjct: 2055 ---PATITEEAVSIDVTQGDPATLQVKFSGTKEITARWFKDGQELTLGQKYKISVTDTVS 2111
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I+ +K D+G+YT N+VG+ SC A +N+ + +IPPSFTK+L + ++ +G+S
Sbjct: 2112 ILKIISTEKRDSGEYTFEVQNDVGRSSCKASINVLDLIIPPSFTKRLKK-MDSIKGSSID 2170
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE VAGS PIS+ W+K++ EI + + +F +N L++ D+G YTC +N A
Sbjct: 2171 LECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISHLEGSDSGTYTCSATNKA 2230
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G C+ + +KE PP F + V+ +QL V G+ P+ I+W K +E+
Sbjct: 2231 GHNQCSGHLTVKE---PPYFVEKPQSQDVNPSTRVQLKALVGGTAPMTIKWFKDNKELHS 2287
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + +LE AD+G Y+C+ SN G+ TSK+ +
Sbjct: 2288 GAARSVWKDDTSTILELFSAKSADSGTYICQLSNDVGTATSKATL--------------- 2332
Query: 1443 XVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDPIPNVKW--TKGKWRQLNQGGRIFIHQ 1613
V F+ +P + V+ + TF ++ G P V W + + + G FI
Sbjct: 2333 FVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPEIRVSWYLDGNEITAIKKHGISFI-- 2390
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A +I +SG Y C A N G ++ L+V E
Sbjct: 2391 -DGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKE 2430
Score = 282 bits (721), Expect = 1e-75
Identities = 167/606 (27%), Positives = 294/606 (48%), Gaps = 1/606 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G +A+ Q L G+ I V+W K + ++ +M F NNVA+L + ++ G+Y+C+
Sbjct: 1977 GGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQ 2036
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A+N G S L+V+E P + + + + T G P + SG++ I+ WFKDG
Sbjct: 2037 AKNDAGIQRCSALLSVKE---PATITEEAVSIDVTQGDPATLQVKFSGTKEITARWFKDG 2093
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ L G + S D V+ L I T++ +G+Y+ N +G +S A + + + PP
Sbjct: 2094 QELTLGQKYKISVTDTVSILKIISTEKRDSGEYTFEVQNDVGRSSCKASINVLDLIIPPS 2153
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L +D++ G S D EC V G+ PI + W KD++EI + Y+ S+ +N+A L I
Sbjct: 2154 FTKRLKKMDSIKGSSIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISH 2213
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
++ D+G YTC A N+ G + C+ L +KE PP F +K ++ + +L+ V
Sbjct: 2214 LEGSDSGTYTCSATNKAGHNQCSGHLTVKE---PPYFVEK-PQSQDVNPSTRVQLKALVG 2269
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+ P+++ W+K+N E+H A + + + +L++ A D+G Y C++SND G+A
Sbjct: 2270 GTAPMTIKWFKDNKELHSGAARSVWKDDTSTILELFSAKSADSGTYICQLSNDVGTATSK 2329
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTV-SEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+++ +KE PP F + +PV V G+ C + G+ IR+ W G EI +
Sbjct: 2330 ATLFVKE---PPQFIKKPSPVLVLRNGQSTTFECQITGTPEIRVSWYLDGNEITAIKKHG 2386
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF +G A + ++G YVC+A N AG+ + ++ V
Sbjct: 2387 ISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIEL---------------KVKEP 2431
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F+ E + + VV+ + +V G V W + +++ + + + L
Sbjct: 2432 PTFIRELKPVEVVKDSDVQLECEVAGTAPFEVTWLRNN-KEIRSSKKYTLTDRVSVFSLH 2490
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAGE 1817
I +D+G Y+C+ N+ G S+ + + E K ++ +LK + +
Sbjct: 2491 ITKCDPSDTGDYQCIVSNEGGSCSSSTKVSLKEPPSFIKKIENVTTVLKSSGTFQSTVAG 2550
Query: 1818 EEEIDI 1835
I I
Sbjct: 2551 SPPISI 2556
Score = 279 bits (714), Expect = 6e-75
Identities = 176/579 (30%), Positives = 283/579 (48%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+V L+C++AGT V+W + + ++R + Y + R +V +L + D +D+
Sbjct: 2440 PVEVVKDSDVQLECEVAGTAPFEVTWLRNNKEIRSSKKYTLTDRVSVFSLHITKCDPSDT 2499
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y C N G SSST ++++E PPSF +++ +V + F+ V+GS PIS+
Sbjct: 2500 GDYQCIVSNEGGSCSSSTKVSLKE---PPSFIKKIENVTTVLKSSGTFQSTVAGSPPISI 2556
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD L++ N+ SF++NVATL I D +G+Y+C A N G A L++ E
Sbjct: 2557 TWLKDDHILEEDDNVHISFVNNVATLQIRAVDNGHSGRYTCQAKNESGVERCYAFLLVQE 2616
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P VD + EC V GT +KV W KD ++I + +S+ N A
Sbjct: 2617 ---PAQILEKAKSVDVTEKDPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVA 2673
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
I V K D+GQYT N+ G SC A L + ++ IPPSFTKKL++ +++ G+S R
Sbjct: 2674 SFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQDIPPSFTKKLTK-MDKILGSSIR 2732
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
+E +V+GS PIS W+K+ E+ +A + N + L+V + D YTCKVSN A
Sbjct: 2733 MECKVSGSLPISAQWFKDGKEVSTSAKYRLVCHENTVSLEVNNLELEDTANYTCKVSNVA 2792
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G C+ + +KEP V + + S EF + ++G+ P +I+W K E+
Sbjct: 2793 GDDACSGILTVKEPPSFLVKPERQQAIPDSTVEFKAV---LKGTPPFKIKWFKDDVELAS 2849
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
C T+ L V + G Y C+ +N GSD+ + +
Sbjct: 2850 GPTCFIGLEGSTSFLNLYSVDASKTGQYTCQVTNDVGSDSCTTML--------------- 2894
Query: 1443 XVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V FV + ++ ++V+ +A K+ G P V W + + +L + +
Sbjct: 2895 LVTEPPKFVKKLEASKIVKAGDSARLECKITGSPEIRVVWYRNE-HELQASDKYRMTFID 2953
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L++ + DSG + C A N G + + V E
Sbjct: 2954 SVAVLQMNNLGTEDSGDFICEAQNPAGSTSCSTKVIVKE 2992
Score = 277 bits (708), Expect = 3e-74
Identities = 183/621 (29%), Positives = 287/621 (46%), Gaps = 4/621 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ V G+SA +C + G + ++W K + ++RP Y + N L +V DSG
Sbjct: 3793 IDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSG 3852
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-GLPVVFECAVSGSEPISV 362
+Y C+A N VG+ S L+V+E PP F ++L Q G + EC +SGS I V
Sbjct: 3853 QYTCQATNDVGKDMCSAQLSVKE---PPKFVKKLEASQVAKHGESIQLECKISGSPEIKV 3909
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WF++ L + SF+++VA L I + +G Y C A N +G AS S L +
Sbjct: 3910 QWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTV-- 3967
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ PP F +PV A+ G F+C ++GT P +V W KD +++RS ++I+
Sbjct: 3968 -KAPPVFTQKPSPVGALKGSDVIFQCEISGTPPFEVVWVKDRKQVRSSKKFKITSKNFDT 4026
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L IL ++ D G+Y C A NEVG D+C + KE PP F KKLS+T G++
Sbjct: 4027 SLHILNLEASDVGEYHCKATNEVGSDTCVCSVKFKE---PPRFVKKLSDT-STLVGDAVE 4082
Query: 903 LEGRVAGSQPISVAWYKNNVE-IHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L V G QPISV W K+ E I + N I+F +N LQ+ D+G Y C++ ND
Sbjct: 4083 LRAVVEGFQPISVVWLKDKGEVIRESENTRISFIDNIATLQLGSPKASDSGKYVCQIKND 4142
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AG+ C++ + + EP + + P+TV+ G L C V G+ + ++W K GRE+
Sbjct: 4143 AGTRECSAVLTVLEPAR---IVEKPEPMTVTTGNPFALECVVAGTPELSVKWFKDGRELS 4199
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
+ +F N A ++ +D G Y + N G T V
Sbjct: 4200 ADSKHHITFINKVASVKIPCAEMSDKGLYSFEVKNSVGKSTCSVSVHVSDRVVPPS---- 4255
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
F+ + + + +A +V G +V W + ++ G +
Sbjct: 4256 --------FIRKLKDTNAILGASAVLECRVSGSAPISVGWFQDG-NEVVSGPKCQSSFSE 4306
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVL 1799
+ L + +D+G Y CVA N G E + L V K + DL + P L
Sbjct: 4307 NVCTLSLSLLEPSDTGTYTCVAANVAGSDECSALLTVQGPKSASHL--DLFVSSRSLPPL 4364
Query: 1800 K--KGAGEEEEIDIMELLKNV 1856
+ + E+ D +E+L +
Sbjct: 4365 RYPEPPSFEQVPDSVEVLPGI 4385
Score = 274 bits (700), Expect = 3e-73
Identities = 174/579 (30%), Positives = 272/579 (46%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+ + L+CQ+ ++ V+W K KL P +K++F + +A+L DS
Sbjct: 1129 PVQSAINKKIRLECQVDEDRKVTVTWNKDGQKLPPGKDHKIYFEDKIASLEIPLAKLKDS 1188
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-GLPVVFECAVSGSEPIS 359
G Y+C A N G SSS +T++E PPSF +++ + G C + GS I
Sbjct: 1189 GTYVCTASNEAGSSSSSATVTIRE---PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQ 1245
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V+WFKD + L + I+ SF+++ A L++ + +G YSC A N +GS + SA +++
Sbjct: 1246 VTWFKDNKELNESNTIRMSFVNSEAVLDLTDVKVTDSGSYSCEAVNDVGSDTCSAEIVVK 1305
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E PP F L P D V G +A +C ++GT P +++W KD ++IRS Y++ ++
Sbjct: 1306 E---PPSFIKTLEPADIVRGTNALLQCEISGTGPFEISWFKDKKQIRSSKKYRLFSQKSL 1362
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I + D G+Y C NEVGK C+A +KE PP+F KK+ + G +
Sbjct: 1363 VSLEIFSFNSADVGEYECVVANEVGKCGCSATHLLKE---PPTFVKKVDD-FTALAGQTV 1418
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L+ V GS+PISV W K + + +F N L + + YTC N+
Sbjct: 1419 TLQAAVRGSEPISVTWMKGQEILKEDGKIKTSFSNGVATLIIPDVQISHGDKYTCLAENE 1478
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS +++KEP K + V V+ G+ L V G+ ++ +W K GR +
Sbjct: 1479 AGSQTSVGELIVKEPAK---IVERAELVQVTAGDPATLEYTVTGTPELKPKWYKDGRPLV 1535
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
S + SF N A L+F D+G Y + SN GS + ++ T
Sbjct: 1536 ASKKYRISFKNNVAQLKFYSAELHDSGQYTFEVSNEVGSSSCETTFTVLDR--------- 1586
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
D FF +++ V + ++ G V W K R+L G +
Sbjct: 1587 ---DIAPFFTKPLRNVASVVGSACRLDCRIAGSLPMRVAWFK-DGRELASGDKYRAAFVE 1642
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A LEI +D+G + C A N G +S+ L V E
Sbjct: 1643 GTASLEIHGVDLSDAGTFTCRATNSVGSKDSSGALVVQE 1681
Score = 270 bits (689), Expect = 5e-72
Identities = 176/596 (29%), Positives = 276/596 (46%), Gaps = 21/596 (3%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTK-LRPTATYKMHFRNNVATLVFNQVDSNDSGEYI 194
VGD+ L+ + G I V W K + +R + ++ F +N+ATL ++DSG+Y+
Sbjct: 4077 VGDAVELRAVVEGFQPISVVWLKDKGEVIRESENTRISFIDNIATLQLGSPKASDSGKYV 4136
Query: 195 CRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFK 374
C+ +N G S LTV E P + + T G P EC V+G+ +SV WFK
Sbjct: 4137 CQIKNDAGTRECSAVLTVLE---PARIVEKPEPMTVTTGNPFALECVVAGTPELSVKWFK 4193
Query: 375 DGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNP 554
DGR L +F++ VA++ I + S G YS N +G ++ S + +++ P
Sbjct: 4194 DGRELSADSKHHITFINKVASVKIPCAEMSDKGLYSFEVKNSVGKSTCSVSVHVSDRVVP 4253
Query: 555 PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTI 734
P F L +A++G SA EC V+G+ PI V W +D E+ SG Q S+ EN L++
Sbjct: 4254 PSFIRKLKDTNAILGASAVLECRVSGSAPISVGWFQDGNEVVSGPKCQSSFSENVCTLSL 4313
Query: 735 LKVDKGDTGQYTCYAVNEVGKDSCTAQLNIK-------------ERLIPP-------SFT 854
++ DTG YTC A N G D C+A L ++ R +PP SF
Sbjct: 4314 SLLEPSDTGTYTCVAANVAGSDECSALLTVQGPKSASHLDLFVSSRSLPPLRYPEPPSF- 4372
Query: 855 KKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKA 1034
+++ ++VE G S + G+ P V W+K + E+ +C I+ +++ L++ +
Sbjct: 4373 EQVPDSVEVLPGISLIFTCVIRGTPPFKVKWFKGSRELVSGESCTISLEDDVTELELLEV 4432
Query: 1035 SMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGS 1214
+G Y+C V+N+AGSA CT+ + +KEP F + L +V G + L G+
Sbjct: 4433 EPSQSGDYSCLVTNEAGSASCTAHLFVKEPA---TFVKRLADFSVETGSPIVLEATYSGT 4489
Query: 1215 EPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSK 1394
PI + W+K + S CS + + +LE + T D Y C N AG D +
Sbjct: 4490 PPISVSWMKNESPLSQSQNCSITTTEKSTILEITESTIEDYAQYSCLIENEAGQDICDAL 4549
Query: 1395 VTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKW 1574
V+ +F+ Q + V T KV G P + W K +
Sbjct: 4550 VSVLEPP---------------YFIEPLQHVEAVIGEPTTLQCKVDGTPEIRIAWYK-EH 4593
Query: 1575 RQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
+L + K + A L I +D G Y C A N G + S+ L + ERK
Sbjct: 4594 TKLRSAPAYKMQFKNNVASLVINKVDHSDIGEYTCKAENSVGAVASSAVLIIKERK 4649
Score = 269 bits (688), Expect = 6e-72
Identities = 178/606 (29%), Positives = 269/606 (44%), Gaps = 29/606 (4%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTK-LRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
V G+ A LQ + G I V W K + +R + ++ F NVATL F + + ++G+
Sbjct: 3098 VVAGEPAELQAYIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGK 3157
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
YIC+ +N G + LTV E P + + TVG EC V+G+ +SV W
Sbjct: 3158 YICQIKNDGGMRENMATLTVLE---PAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEW 3214
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+KDG+ L + SF + ++TL I +R AG Y+ N +G +S +A + +++
Sbjct: 3215 YKDGKLLTSSQKHKFSFYNKISTLKILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRM 3274
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP F L V+G S EC V G+ PI VAW + +I SG YQ ++ +N L
Sbjct: 3275 VPPSFTRRLRDTVGVLGTSCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTL 3334
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
+ +D D G YTC A N G D C A L ++E PPSF K+ E +E G +
Sbjct: 3335 QLNSLDSSDMGSYTCVAANAAGSDECRAALAVQE---PPSFVKE-PEPLEILPGKNVTFT 3390
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+ G+ P V W++ E+ C I F++ L++ + +G YTC VSN+AG
Sbjct: 3391 SVIRGTPPFKVGWFRGARELVRGDQCNIYFEDTVAELELFNVDISQSGEYTCVVSNNAGQ 3450
Query: 1089 ALCTSSIVIK----------------------------EPKKPPVFDQHLTPVTVSEGEF 1184
CT+ + +K +P F + L+ +V G+
Sbjct: 3451 TSCTTRLFVKGLLACICSSDFLYAAIYVLFLGLIAVLCHSPEPATFVKKLSDHSVEPGKS 3510
Query: 1185 LQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASN 1364
+ L G+ PI + W K G I S+RCS T +LE + TK DAG Y C+ N
Sbjct: 3511 IILESTYTGTLPIAVTWKKDGFNISQSERCSIVTTEKTCILEILNSTKKDAGQYSCEIEN 3570
Query: 1365 VAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPI 1544
AG D K+ + +FV+E + + + + +V G P
Sbjct: 3571 EAGKDVCKALLLNVILSSLEPP----------YFVTELEPLEASVGDSVSLQCQVAGTPE 3620
Query: 1545 PNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNL 1724
V W KG +L + + A L DSG Y C A N G S
Sbjct: 3621 ITVSWYKGD-TKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTAASKTVF 3679
Query: 1725 QVNERK 1742
++ ER+
Sbjct: 3680 RIQERQ 3685
Score = 255 bits (651), Expect = 1e-67
Identities = 171/581 (29%), Positives = 256/581 (44%)
Frame = +3
Query: 3 PVKVTV1732 VHPEPRVTWYKSGQKIKPGDDDRKYIFESDKGLYQLTINSVTMDDDAEYTVVARNKYGED 31791
Query: 1092 LCTSSIVIKEPKKP------PVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
C + + + P P+F + L EG+ + V G P ++W K GR
Sbjct: 31792 SCKAKLTVTPHPPPSDTTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGRP 31851
Query: 1254 IKPSDRCSFSFAN-GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS 1391
+ L +D D G Y A+N AGS + ++
Sbjct: 31852 LSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSSSCQA 31898
Score = 74.7 bits (182), Expect = 3e-13
Identities = 154/769 (20%), Positives = 254/769 (33%), Gaps = 158/769 (20%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHF-RNNVATLVFNQVDSNDSG 185
++ G + C+++G P ++WYK +++ Y M F ++ A+L V D G
Sbjct: 1298 RILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYHMDFLQDGRASLRIPVVLPEDEG 1357
Query: 186 EYICRAENSVGE--------------VSSSTFLTVQEQ---------------------- 257
Y A N G +S+ T++ E
Sbjct: 1358 IYTAFASNMKGNAICSGKLYVEPAAPLSAPTYIPTPEPVSRIRSISPRSVSRSPIRMSPA 1417
Query: 258 KLPPSFSRQLRDVQET-------------VGLPVVFECA----------VSGSEPISVSW 368
++ P+ R ++ET V P F+C V G W
Sbjct: 1418 RMSPARMSPGRRLEETDESQLERLYKPVFVLKPTSFKCVEGQTARFDLKVVGRPMPETFW 1477
Query: 369 FKDGRPL-KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL--T 539
F DG+ + D + D +L I S +G+++ A N G +S S L +
Sbjct: 1478 FHDGQQIVNDYTHKVVVKEDGTQSLLIVPATPSDSGEWTVVAQNRAGKSSISVILTVEAV 1537
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E + P F L ++ G + + TG + W K N EI Y +E +
Sbjct: 1538 EHQVKPVFVEKLRNLNIKEGSRLEMKVRATGNPNPDIVWLK-NSEIIVPHKYPKIRIEGT 1596
Query: 720 AHLTILKVDKG---DTGQYTCYAVNEVGKDSCTAQLNI---------------------- 824
LK+D D+ YT A+N+ G+D+ ++N+
Sbjct: 1597 KGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERRLIIPRGTYRA 1656
Query: 825 ---------------------------KERLIPPSFTKKLSETVEETEGNS-FRLEGRVA 920
KE+ P F KKL+ + G + F
Sbjct: 1657 KEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPI 1716
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G + V W + + + + L A D+G+ TC+ +N G+ +
Sbjct: 1717 GDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYAVAYSRDSGVITCRATNKYGTDHTS 1776
Query: 1101 SSIVIKEPK----------------------------------------KPPVFDQHLTP 1160
+++++K+ K + P P
Sbjct: 1777 ATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLFPEP 1836
Query: 1161 VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAG 1340
V V EGE + C V G ++ W G+ I+ S R + +G L+ D D G
Sbjct: 1837 VRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY-DGIHYLDIVDCKSYDTG 1895
Query: 1341 DYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFI 1520
+ A N G K K+ F V EP ++ F
Sbjct: 1896 EVKVTAENPEGVIDHKVKLEIQQREDFRSVLRRAPEPKPEFHVHEPGKLQ--------FE 1947
Query: 1521 AKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTK--TDSGLYRCVAFNK 1694
+ P+ + TK R L + RI H+K E E+R K T+ G Y
Sbjct: 1948 VQKVDRPVDTTE-TKEIVR-LKRAERI-THEKVSEESEELRSKFKRRTEEGYY------- 1997
Query: 1695 HGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEIDIME 1841
E+ +++ RKK E E LR ++ K EEE+ + E
Sbjct: 1998 ----EAITAVELKSRKKDESYEELLRKTKEELLHWTKELTEEEKKALAE 2042
Score = 72.8 bits (177), Expect = 1e-12
Identities = 131/561 (23%), Positives = 215/561 (38%), Gaps = 1/561 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+V VG++A + +L+ P++ W L + ++ LV + +G
Sbjct: 11777 VEVFVGETARFEIELS-EPDVHGQWKLKGEPLTASPDCEIIEDGKKHILVLYNCRLDMTG 11835
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+ +A N+ S+ L V+E LP F L DV+ FEC VS EP LDNVATLNIFQTDRSFAGQYSCTATNPIGSA 512
VSG++ + VSW+ + +K + + ++ L I + G Y+ A+N +G
Sbjct: 3367 RVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQV 3425
Query: 513 SSSARLILT----------------EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPI 644
SS+A L L E + P + P++ +G A F C + +
Sbjct: 3426 SSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNV 3485
Query: 645 KVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI 824
+ W K REI I + + L IL+ D G+YTC A NE G SCTA L +
Sbjct: 3486 RFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 3545
Query: 825 KERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKN 1004
E PP+F + +++ G + + V G+ I W K+ + P+ N I+
Sbjct: 3546 TEAY-PPTFLSR-PKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAE 3603
Query: 1005 NALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEF 1184
N +L++ ++ D G+Y+CK SN G+ +C + ++I + P F + L PV + +
Sbjct: 3604 NKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK---PHFIKELEPVQSAINKK 3660
Query: 1185 LQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASN 1364
+ L C V + + W K G+++ P F + A LE D+G YVC ASN
Sbjct: 3661 VHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASN 3720
Query: 1365 VAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPI 1544
AGS + + VT + F S ++ +A K+ G P+
Sbjct: 3721 EAGSSSCSATVTVR--------------EPPSFVKKVDPSYLMLPGESARLHCKLKGSPV 3766
Query: 1545 PNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNL 1724
V W K ++L++ + ++ EA L+I D DSG Y C A N G + +
Sbjct: 3767 IQVTWFKNN-KELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEI 3825
Query: 1725 QVNE 1736
+ E
Sbjct: 3826 VIKE 3829
Score = 179 bits (454), Expect = 8e-45
Identities = 152/595 (25%), Positives = 260/595 (43%), Gaps = 30/595 (5%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+KV A +C+++ P+I V W K D +L+ T K+ V L+ +D+G
Sbjct: 3067 IKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAG 3125
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y A G VS++ S ++++ +++ + V FE + +
Sbjct: 3126 KYTVVAG---GNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAV-VEFEV---NEDDVDAH 3178
Query: 366 WFKDGRPLKDGPNIQTSFL--DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
W+KDG + + ++ + + I +T +S AG+Y+ A G SS L +
Sbjct: 3179 WYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA----GRNRSSVTLYVN 3234
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
PP L PV G+ A F ++G K++W K+ + + +G ++ +L +
Sbjct: 3235 -APEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTG--FKCKFLHDG 3291
Query: 720 AHLTILKVDK--GDTGQYTCYAVNEVGKDSCTAQLNIKERLI----------PPSFTKKL 863
T+L ++ D YTC A N+ G + +A L+++ + PP+ L
Sbjct: 3292 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPL 3351
Query: 864 SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMG 1043
+TV +EG R + RV+G+ + V+WY + +I P+ +T + L++ +A
Sbjct: 3352 QDTVT-SEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPE 3409
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEP----------------KKPPVFDQHLTPVTVSE 1175
D G YT SN G T+++ ++ P K PV + + P+ V+
Sbjct: 3410 DEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVAL 3469
Query: 1176 GEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCK 1355
G + +C ++ + +R QW KAGREI SD+CS + + LE D G+Y CK
Sbjct: 3470 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCK 3529
Query: 1356 ASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGG 1535
ASN GS + + +T F+S P+S+ A FI V G
Sbjct: 3530 ASNEYGSVSCTATLTVTEAYPPT-------------FLSRPKSLTTFVGKAAKFICTVTG 3576
Query: 1536 DPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG 1700
P+ W K L+ I ++ LE+ + T D G+Y C A NK G
Sbjct: 3577 TPVIETIWQK-DGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFG 3630
Score = 132 bits (331), Expect = 2e-30
Identities = 136/522 (26%), Positives = 215/522 (41%), Gaps = 9/522 (1%)
Frame = +3
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-------GLPVVFECAVSGSEPISV 362
+ ++ E T T + K+ S S + + E + G F V G
Sbjct: 2050 KKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC 2109
Query: 363 SWFKDGRPLKDGPNIQTSFL-DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
W+K+G ++ I + DNV L I + A N G SS A +L
Sbjct: 2110 EWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHA-FLLV 2168
Query: 540 EGRNPPFFDIPLAPVDAVVGES-ADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
+ + F L V A ++ A FEC T +KV W KD E+ G Y++
Sbjct: 2169 QAKQLITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGMEVHEGDKYRMHSDRK 2227
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
L+IL +D D Y+C V + + TA+L ++ ++ F K+L + +E E S
Sbjct: 2228 VHFLSILTIDTSDAEDYSCVLVEDENVKT-TAKLIVEGAVV--EFVKELQD-IEVPESYS 2283
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
LE + + I WY N+VE+ IT + L VK + D G Y+ +
Sbjct: 2284 GELEC-IVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVI-- 2340
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
D C +K +P Q L+ V EG+ +QL V E + W+K G+E+
Sbjct: 2341 DGKKTTCK----LKMKPRPIAILQGLSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQEV 2395
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
+PSDR + +L +D+TK DAG+Y + S + + V
Sbjct: 2396 QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSV------------- 2442
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
VD ++ + + V+E T A KV + +VKW Q+ R+ K
Sbjct: 2443 -YSVD----VITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLND-EQIKPDDRVQAIVK 2496
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
G + +L I T +D G Y+ + G +E+N NL V + K
Sbjct: 2497 GTKQRLVINRTHASDEGPYKLIV----GRVETNCNLSVEKIK 2534
Score = 131 bits (330), Expect = 2e-30
Identities = 122/445 (27%), Positives = 198/445 (44%), Gaps = 3/445 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKL-RPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
G A + ++ G P+ WYK K+ R Y +NV LV V + DS +
Sbjct: 2092 GSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMV 2151
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRD-VQETVGLPVVFECAVSGSEP-ISVSWF 371
+A N GE SS FL VQ ++L +F+++L+D V + FEC SEP + V W+
Sbjct: 2152 KAINIAGETSSHAFLLVQAKQL-ITFTQELQDVVAKEKDTMATFECET--SEPFVKVKWY 2208
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDG + +G + V L+I D S A YSC + ++A+LI+ EG
Sbjct: 2209 KDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVED-ENVKTTAKLIV-EGAV 2266
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
F L ++ S + EC + + I+ W ++ E++S G Y I+ +LT
Sbjct: 2267 VEFVK-ELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2324
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
+ V K D G+Y+ + ++ GK + T +L +K R P + + LS+ + EG+ +LE
Sbjct: 2325 VKDVTKEDQGEYS-FVID--GKKT-TCKLKMKPR--PIAILQGLSDQ-KVCEGDIVQLEV 2377
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
+V+ + + W K+ E+ P+ I + +L ++ + DAG Y+ + S
Sbjct: 2378 KVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLST 2436
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
S+ + P L V V EG L C V + ++W +IKP DR
Sbjct: 2437 SGRVSVYSVDVITP------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR 2490
Query: 1272 CSFSFANGTAVLEFKDVTKADAGDY 1346
L +D G Y
Sbjct: 2491 VQAIVKGTKQRLVINRTHASDEGPY 2515
Score = 123 bits (309), Expect = 6e-28
Identities = 148/636 (23%), Positives = 259/636 (40%), Gaps = 27/636 (4%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV V+ G+ L C + G+ I + W K +++P+ F + A L V DS
Sbjct: 8354 PVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADS 8413
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQK-LPPSFSRQLRD-----VQETVGLPVVFECAVS- 341
G+Y+C+A N G ++ + +T++++ + P+ + D V E + VV + +
Sbjct: 8414 GDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATF 8473
Query: 342 ----GSEPI-SVSWFKDG-RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPI 503
G +PI +V W K R L G + + A L I T ++ +G Y C A N
Sbjct: 8474 IAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEH 8533
Query: 504 GSASSSARLILTEGRNPPFFDIPLAPV---DAVVGESADFECHVTGTQPIKVAWAKD-NR 671
G S+ L + E + + L + ++ + A E + + +K K+ +
Sbjct: 8534 GEIESNVNLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEEEEIDIMELLKNVDPKEYEK 8593
Query: 672 EIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQ---LNIKERLI- 839
R G L + L + + + +T + + +D + I++RL
Sbjct: 8594 YARMYGITDFRGLLQAFEL-LKQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQ 8652
Query: 840 --PPSFTKKL-SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNA 1010
P + K + ++TV + F ++ ++ + I ++WYK ++ P+ EI+ +
Sbjct: 8653 TEPVTLIKDIENQTVLKDNDAVFEIDIKINYPE-IKLSWYKGTEKLEPSDKFEISIDGDR 8711
Query: 1011 LLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQ 1190
L+VK + D G Y SA T VI+ P +++HL VT+ EG+
Sbjct: 8712 HTLRVKNCQLKDQGNYRLVCGPHIASAKLT---VIE-----PAWERHLQDVTLKEGQTCT 8763
Query: 1191 LSCHVRGSEP-IRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNV 1367
++C S P ++ +W + GR +KP R + L DV D G Y CK ++
Sbjct: 8764 MTCQF--SVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDL 8821
Query: 1368 AGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIP 1547
S + + + F Q+I V E +ATF +V D
Sbjct: 8822 ETSAELRIEAE------------------PIQFTKRIQNIVVSEHQSATFECEVSFDD-A 8862
Query: 1548 NVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVA-FNKHGEIESNVNL 1724
V W KG +L + + G + I + T D G+Y +A GE S L
Sbjct: 8863 IVTWYKGP-TELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAEL 8921
Query: 1725 QVNERK-KQEKIEGDLRAMLKKTPVLKKGAGEEEEI 1829
+ ++ K E D+ P + A EEI
Sbjct: 8922 YLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEI 8957
Score = 122 bits (306), Expect = 1e-27
Identities = 141/560 (25%), Positives = 228/560 (40%), Gaps = 4/560 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+V ++A + +++ +I +W L T ++ + +LV + + +G
Sbjct: 12116 VEVMETETARFETEIS-EDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTG 12174
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+A N V SS L V+ + + R L+DV T G F+C +S E I V
Sbjct: 12175 GVDFQAAN----VKSSAHLRVKPRVI--GLLRPLKDVTVTAGETATFDCELS-YEDIPVE 12227
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+ G+ L+ + V TL + AG+ TA + + A L + E
Sbjct: 12228 WYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD----FKTHANLFVKEP 12283
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P F PL G +A EC V+ + KV W K+ EI Y+I
Sbjct: 12284 --PVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEIVADGRVRK 12340
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPP--SFTKKLSET-VEETEGNS 896
L I D YTC A + K SC LN+ +PP F + L++ V E E
Sbjct: 12341 LVIHDCTPEDIKTYTCDAKDF--KTSCN--LNV----VPPHVEFLRPLTDLQVREKEMAR 12392
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
F E + V W+K+ EI +I K +L + K + D Y+C+V
Sbjct: 12393 FECE---LSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRT 12449
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEP-IRIQWLKAGRE 1253
S + T V++E VF ++L + VSE + ++L C V S+P + W K E
Sbjct: 12450 ARTSGMLT---VLEE---EAVFTKNLANIEVSETDTIKLVCEV--SKPGAEVIWYKGDEE 12501
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
I + R +L ++ DAG+Y C+ S + KV
Sbjct: 12502 IIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLP----SSRTDGKVKVHELAAE---- 12553
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
F+S+PQ++ ++E A F+ + + P V+W + + L G + +
Sbjct: 12554 ----------FISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDD-KTLESGDKYDVIA 12601
Query: 1614 KGDEAKLEIRDTTKTDSGLY 1673
G + L ++D T D G Y
Sbjct: 12602 DGKKRVLVVKDATLQDMGTY 12621
Score = 118 bits (295), Expect = 2e-26
Identities = 151/669 (22%), Positives = 250/669 (37%), Gaps = 44/669 (6%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVD--SNDS 182
+V G + + P V WY +L+ ++ K+H+ N L +D ++DS
Sbjct: 32384 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTLEILDCHTDDS 32441
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y N GE S L V +++ Q RD E V V E ++ +E +V
Sbjct: 32442 GTYRAVCTNYKGEASDYATLDVTGGDYT-TYASQRRD--EEVPRSVFPE--LTRTEAYAV 32496
Query: 363 SWFKDGRPLKDGPNIQ---TSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL- 530
S FK ++ +++ + + +L+ ++ S + + + S++ ++
Sbjct: 32497 SSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIK 32556
Query: 531 ------ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
ILT+ R+ ++ GESA F C G V W + + + +
Sbjct: 32557 TTLAARILTKPRSMTVYE----------GESARFSCDTDGEPVPTVTWLRKGQVLSTSAR 32606
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET 872
+Q++ + + I V D G Y+ N GK L I++ + T+K +
Sbjct: 32607 HQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARV----TEKAVTS 32662
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAG 1052
+ R++ A P V K+ HP A
Sbjct: 32663 PPRVKSPEPRVKSPEAVKSPKRV---KSPEPSHPKA------------------------ 32695
Query: 1053 LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGS--EPIR 1226
VS T + PP Q L + E +L+C V S
Sbjct: 32696 -----VSPTETKPTPTEKVQHLPVSAPPKITQFLK--AEASKEIAKLTCVVESSVLRAKE 32748
Query: 1227 IQWLKAGREIKPSDRCSFSF-ANGTAVLEFKDVTKADAGDYVCKASNVAG---------- 1373
+ W K G+++K + F + A+GT L+ ++T++D G+YVC+ S G
Sbjct: 32749 VTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMG 32808
Query: 1374 -------------SDTSKS--KVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTT 1508
S+T KS K T + K V+ Q V +
Sbjct: 32809 QAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSV 32868
Query: 1509 ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAF 1688
A F K G+P P WTK + + QGG+ + + LEI T +DSGLY C
Sbjct: 32869 AKFAVKATGEPRPTAIWTKDG-KAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK 32927
Query: 1689 NKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEIDIMEL----LKNV 1856
N G + S+ L + K E + + + TP +K A +EEI L +K
Sbjct: 32928 NSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITP--QKKAVVQEEISQKALRSEEIKMS 32985
Query: 1857 DPKEYEKYA 1883
+ K EK A
Sbjct: 32986 EAKSQEKLA 32994
Score = 111 bits (278), Expect = 2e-24
Identities = 147/648 (22%), Positives = 247/648 (38%), Gaps = 65/648 (10%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G+S +L+C ++G P V+WY+ D ++ + +++ F++ +A L+ + + DSG
Sbjct: 952 VTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSG 1011
Query: 186 EYICRAENSVGEVSSSTFLTVQ-------------------EQKLPPSFSRQLRD----- 293
+ C A N G VS+S +L VQ E++ S + D
Sbjct: 1012 RFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTE 1071
Query: 294 ------------------VQETV-GLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTS 416
VQ+ V G VVF C V G+ V W K G PL G + S
Sbjct: 1072 EQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVS 1131
Query: 417 FLDNV--ATLNIFQTDRSFAGQYSCTATNPIGSASSSARL-------ILTEGRNPPFFDI 569
+ L I T AG+Y+ N G S+SA L +L + + +
Sbjct: 1132 YNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQT 1191
Query: 570 PLAPV--DAVVGESA------DFECHVTGTQP-IKVAWAKDNREIRSGGNYQISYLENSA 722
+ + VGE+A ++E Q I+ AKD +R+ Q ++ +
Sbjct: 1192 QVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFE 1251
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
I +++ + E G++ ++ E + F ++ + EG
Sbjct: 1252 ERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESE-AVESGFDSRI-KNYRILEGMGVT 1309
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITF-KNNALLLQVKKASMGDAGLYTCKVSND 1079
+++G +AWYK+ I ++ F ++ L++ D G+YT SN
Sbjct: 1310 FHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNI 1369
Query: 1080 AGSALCTSSIVIKEPKKP---PVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
G+A+C+ + + EP P P + L PV+ LS PIR+ +
Sbjct: 1370 KGNAICSGKLYV-EPAAPLGAPTYIPTLEPVS----RIRSLSPRSVSRSPIRMSPARMSP 1424
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
R S + + LE +T +S++
Sbjct: 1425 ARMSPARMSPARMSPGRRLE----------------------ETDESQLERLY------- 1455
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
K FV +P S + +E TA F KV G P+P W + +N +
Sbjct: 1456 --------KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVI 1507
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEK 1754
++ L I T +DSG + VA N+ G +V L V + Q K
Sbjct: 1508 KEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVK 1555
Score = 108 bits (270), Expect = 2e-23
Identities = 136/565 (24%), Positives = 228/565 (40%), Gaps = 3/565 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G A L+C+++ V WY D +++P + + LV N+ ++D G
Sbjct: 2454 VNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEG 2513
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y + VG V ++ L+V++ K+ R LRD+ T VVFE +S S I V
Sbjct: 2514 PY----KLIVGRVETNCNLSVEKIKI----IRGLRDLTCTETQNVVFEVELSHS-GIDVL 2564
Query: 366 W-FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W FKD + +K + + L + + G+Y+ A G +S +L +
Sbjct: 2565 WNFKD-KEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYA----GENMTSGKLTVAG 2619
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
G PL + A FEC V K W +D + + N + +
Sbjct: 2620 GA----ISKPLTDQTVAESQEAVFECEVANPDS-KGEWLRDGKHLPLTNNIRSESDGHKR 2674
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I D G+YT +V +A+L ++ I + K L TV ET+ F
Sbjct: 2675 RLIIAATKLDDIGEYT----YKVATSKTSAKLKVEAVKIKKTL-KNL--TVTETQDAVFT 2727
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
+E + V W KN V + I+ K L++K ++ D +Y ++
Sbjct: 2728 VE--LTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2785
Query: 1083 GSA-LCTSSI-VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
SA L ++ +IK+PK VT E + V + + ++W EI
Sbjct: 2786 ASARLHVETVKIIKKPK----------DVTALENATVAFEVSV-SHDTVPVKWFHKSVEI 2834
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
KPSD+ L ++++ +DAG+Y V G K+K+
Sbjct: 2835 KPSDKHRLVSERKVHKLMLQNISPSDAGEYTA----VVGQLECKAKLFVE---------- 2880
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
L ++I V E TA+F +V +P++ G ++++ +I + +
Sbjct: 2881 ------TLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVV--Q 2932
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFN 1691
G +L I +T+ DS Y V N
Sbjct: 2933 GKLHQLIIMNTSTEDSAEYTFVCGN 2957
Score = 107 bits (268), Expect = 3e-23
Identities = 134/592 (22%), Positives = 223/592 (37%), Gaps = 4/592 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++V+ D+ L C+++ P V WYKGD ++ T Y++ LV D+G
Sbjct: 12472 IEVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAG 12530
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y CR SS T V+ +L F + ++++ G F C++S E V
Sbjct: 12531 NYNCRLP------SSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQ 12583
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W +D + L+ G L + G Y +G+A ++A L + E
Sbjct: 12584 WKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTVIEK 12639
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
+PL + F C V T+ K W ++ I Y I +
Sbjct: 12640 LR---IVVPLKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVYT 12695
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKD-SCTAQLNIKE---RLIPPSFTKKLSETVEETEGN 893
L I D Y N G++ A L ++E R++ P K ET+E+
Sbjct: 12696 LRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEP---LKDIETMEKKSVT 12752
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
+ R+ +++ W KN E+ +L +K D G Y
Sbjct: 12753 FWCKVNRL----NVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAG 12808
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
D A ++I+ P + F +HL TV+E + SC + E ++W + GRE
Sbjct: 12809 QDKSVA---ELLIIEAPTE---FVEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGRE 12861
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
IK + F L KD D +Y C G + KS+
Sbjct: 12862 IKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC------GVEDRKSRARLFVE------- 12908
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
+ + + PQ I F+A++ D + V+W + + QG + +
Sbjct: 12909 -----EIPVEIIRPPQDILEAPGADVVFLAELNKDKV-EVQWLRNN-MVVVQGDKHQMMS 12961
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDL 1769
+G +L+I D D G YR +A +K E+ L++ K + + DL
Sbjct: 12962 EGKIHRLQICDIKPRDQGEYRFIAKDK----EARAKLELAAAPKIKTADQDL 13009
Score = 106 bits (264), Expect = 9e-23
Identities = 70/220 (31%), Positives = 110/220 (50%), Gaps = 3/220 (1%)
Frame = +3
Query: 267 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDG--PNIQTSFLDNVATL 440
P+F++ L+ V G FE +SG VSWF+DG+ + P +Q SF D A L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 441 NIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFEC 620
I ++ +G+YS ATN G A+S+A L++ PP F L + G +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQV 125
Query: 621 HVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKD 800
VTG V + +D EI+S ++QIS + L I + D+G Y+ A N VG+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRA 185
Query: 801 SCTAQLNIK-ERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+ TA+L ++ E +P TK + T + +E R+E ++
Sbjct: 186 TSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKI 225
Score = 105 bits (261), Expect = 2e-22
Identities = 138/575 (24%), Positives = 219/575 (38%), Gaps = 3/575 (0%)
Frame = +3
Query: 3 PVK-VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSND 179
P+K VTV + + + T E V W KG ++ + + + LV N +D
Sbjct: 11491 PLKDVTVPERRQARFECVLTREANVIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDD 11550
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
G Y E + S+ F+T K F L D G F C +S E +
Sbjct: 11551 EGVYTAEVEGK--KTSARLFVTGIRLK----FMSPLEDQTVKEGETATFVCELS-HEKMH 11603
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V WFK+ L + S L + + Q + SS+A+L +
Sbjct: 11604 VVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKA----QVKELSSTAQLKVL 11659
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E P+F + L AV + +C V+ P+K W KD EI Y I
Sbjct: 11660 EA--DPYFTVKLHDKTAVEKDEITLKCEVSKDVPVK--WFKDGEEIVPSPKYSIKADGLR 11715
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I K D D G+Y C + G D A + ++ RLI +K VE G +
Sbjct: 11716 RILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARLIK---VEKPLYGVEVFVGETA 11768
Query: 900 RLEGRVAGSQP-ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
E + S+P + W + + +CEI +L + +G G +VS
Sbjct: 11769 HFE--IELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTG----EVSF 11822
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
A +A +++ +KE P +F L+ V V E + + C V EP +WLK +EI
Sbjct: 11823 QAANAKSAANLKVKE--LPLIFITPLSDVKVFEKDEAKFECEV-SREPKTFRWLKGTQEI 11879
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
DR + K D Y+ +A + TS +
Sbjct: 11880 TGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAED---KHTSGKLI------------- 11923
Query: 1437 XXXVDG-KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
++G +L F++ + + EK +A F ++ D I VKW K R L+ + +
Sbjct: 11924 ---IEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQR-LHTTRSVSMQD 11978
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNV 1718
+G + +D + D+ R A E + V
Sbjct: 11979 EGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTV 12013
Score = 103 bits (256), Expect = 8e-22
Identities = 138/561 (24%), Positives = 229/561 (40%), Gaps = 3/561 (0%)
Frame = +3
Query: 24 DSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRA 203
+SAS +++ G KG+ LRP+ T ++ L ++V + +GE + +A
Sbjct: 11412 ESASFDAEISEADIPGQWKLKGEL-LRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQA 11470
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGR 383
N++ ++ LTV+E +L F+ L+DV FEC ++ +V W K
Sbjct: 11471 LNAI----TTAILTVKEIEL--DFAVPLKDVTVPERRQARFECVLT--REANVIWSKGPD 11522
Query: 384 PLK--DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
+K D +I ++ +N Q D G Y T + +SARL +T R
Sbjct: 11523 IIKSSDKFDIIADGKKHILVINDSQFDDE--GVY----TAEVEGKKTSARLFVTGIRLK- 11575
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F PL GE+A F C ++ + + V W K++ ++ + IS + L +
Sbjct: 11576 -FMSPLEDQTVKEGETATFVCELSH-EKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMK 11633
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+V D Q +V + S TAQL + E P FT KL + E + L+ V
Sbjct: 11634 EVTLDDISQIKA----QVKELSSTAQLKVLEA--DPYFTVKLHDKTA-VEKDEITLKCEV 11686
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
S+ + V W+K+ EI P+ I +L++KKA + D G Y C D A
Sbjct: 11687 --SKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANV 11744
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEP-IRIQWLKAGREIKPSDRC 1274
T + + +KP L V V GE + SEP + QW G+ + S C
Sbjct: 11745 TVEARLIKVEKP------LYGVEVFVGETAHFEIEL--SEPDVHGQWKLKGQPLTASPDC 11796
Query: 1275 SFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDG 1454
+L + G+ +A+N + K K +
Sbjct: 11797 EIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVK------------------EL 11838
Query: 1455 KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKL 1634
L F++ ++V EK A F +V +P +W KG +++ R + + G + +
Sbjct: 11839 PLIFITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGT-QEITGDDRFELIKDGTKHSM 11896
Query: 1635 EIRDTTKTDSGLYRCVAFNKH 1697
I+ D Y A +KH
Sbjct: 11897 VIKSAAFEDEAKYMFEAEDKH 11917
Score = 101 bits (252), Expect = 2e-21
Identities = 120/541 (22%), Positives = 207/541 (38%), Gaps = 52/541 (9%)
Frame = +3
Query: 264 PPSFSRQLRDV--QETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSF-LDNVA 434
PP ++ L+ +E L V E +V ++ V+W+KDG+ LK+ + Q + D
Sbjct: 32717 PPKITQFLKAEASKEIAKLTCVVESSVLRAK--EVTWYKDGKKLKENGHFQFHYSADGTY 32774
Query: 435 TLNIFQTDRSFAGQYSCTATNPIGSASSSARLI--------------------------- 533
L I S G+Y C + G++ ++ + +
Sbjct: 32775 ELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTES 32834
Query: 534 ----LTEGRNP-PFFDIPLAPV---DAVVGES--ADFECHVTGTQPIKVAWAKDNREIRS 683
TE + P P P+ D V A F TG W KD + I
Sbjct: 32835 TVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQ 32894
Query: 684 GGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKL 863
GG Y++S + L I K D D+G YTC N G S + +L IK
Sbjct: 32895 GGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK------------ 32942
Query: 864 SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMG 1043
+++TE + + + P A + + + EI K + Q K A
Sbjct: 32943 --AIKDTEAQKVSTQ-KTSEITPQKKAVVQEEISQKALRSEEI--KMSEAKSQEKLALKE 32997
Query: 1044 DAG--LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHL----------TPVTVSEGEFL 1187
+A L + +V A ++L SIV +E K + + T ++++EG+ L
Sbjct: 32998 EASKVLISEEVKKSAATSL-EKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRL 33056
Query: 1188 QLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNV 1367
L ++ G+ ++ W+ G E+ S+ + + L K + D G C +
Sbjct: 33057 VLKANIAGATDVK--WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTK 33114
Query: 1368 AGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIP 1547
G + +T F+S+P+S + E F ++ G+P P
Sbjct: 33115 EGIVKCQYDLTLSKELSDAPA-----------FISQPRSQNINEGQNVLFTCEISGEPSP 33163
Query: 1548 NVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
++W K ++ + I + + LEIR+ + +DSG Y A N G+ + +L
Sbjct: 33164 EIEWFKNN-LPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLM 33222
Query: 1728 V 1730
V
Sbjct: 33223 V 33223
Score = 101 bits (251), Expect = 3e-21
Identities = 150/615 (24%), Positives = 239/615 (38%), Gaps = 14/615 (2%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
VG SA +C ++ + I +W K + +R + ++ L V +D+GEY C
Sbjct: 11132 VGSSAIFECLVSPSTAI-TTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTC 11190
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQL-RDVQETVGLPVVFECAVSGSEPISVSWFK 374
E +S+ L V+E LP F + L +V G P+ C ++ V W K
Sbjct: 11191 VLRLGNKEKTSTAKLVVEE--LPVRFVKTLEEEVTVVKGQPLYLSCELNKER--DVVWRK 11246
Query: 375 DGRPLKDGP-NIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
DG+ + + P I + + L I D + AG Y+ T N SS ++ R+
Sbjct: 11247 DGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRD 11306
Query: 552 ---PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P D + P + F C + P + W K EI + N + L +
Sbjct: 11307 WLVKPIRDQHVKPKGTAI-----FACDIAKDTP-NIKWFKGYDEIPAEPNDKTEILRDGN 11360
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE-TVEETEGNSF 899
HL LK+ YAV GK A+L + ER + K + + T+ E E SF
Sbjct: 11361 HL-YLKIKNAMPEDIAEYAVEIEGK-RYPAKLTLGEREV--ELLKPIEDVTIYEKESASF 11416
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
E I W + P+ CEI + L + K + AG +V
Sbjct: 11417 DAE---ISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAG----EVLYQ 11469
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
A +A+ T+ + +KE + F L VTV E + C + + + W K IK
Sbjct: 11470 ALNAITTAILTVKEIELD--FAVPLKDVTVPERRQARFECVL--TREANVIWSKGPDIIK 11525
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
SD+ +L D D G Y + V G TS
Sbjct: 11526 SSDKFDIIADGKKHILVINDSQFDDEGVY---TAEVEGKKTSARLFVTGI---------- 11572
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
+L F+S + V E TATF+ ++ + + +V W K +L+ + I +G
Sbjct: 11573 -----RLKFMSPLEDQTVKEGETATFVCELSHEKM-HVVWFKND-AKLHTSRTVLISSEG 11625
Query: 1620 DEAKLEIRDTTKTDSGLYRC-------VAFNKHGEIESNVNLQVNERKKQEKIEGDLRAM 1778
KLE+++ T D + A K E + ++++++ EK E L+
Sbjct: 11626 KTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCE 11685
Query: 1779 LKK-TPVLKKGAGEE 1820
+ K PV GEE
Sbjct: 11686 VSKDVPVKWFKDGEE 11700
Score = 96.3 bits (238), Expect = 9e-20
Identities = 80/302 (26%), Positives = 120/302 (39%), Gaps = 35/302 (11%)
Frame = +3
Query: 318 VVFECAVSG-SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTAT 494
V + C + + V+W+ R L++ + ++ D VA L + + G Y C
Sbjct: 31585 VKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVV 31644
Query: 495 NPIGSASSSARLILTEGRN-------------------------PPFFDIPLAPVDAVVG 599
N G SS A L + R PP F +PL A VG
Sbjct: 31645 NDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVG 31704
Query: 600 ESADFECHVTGTQPIKVAWAKDNREIRSGGN---YQISYLENSAHLTILKVDKGDTGQYT 770
E+ F +T V W K ++I+ G N Y + LTI V D +YT
Sbjct: 31705 ENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYT 31764
Query: 771 CYAVNEVGKDSCTAQLNIKERLIPPSFT-----KKLSETVEETEGNSFRLEGRVAGSQPI 935
A N+ G+DSC A+L + P T K+L E EG S E RV+G P
Sbjct: 31765 VVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPP 31824
Query: 936 SVAWYKNNVEIHPTANCEITFKN-NALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIV 1112
++ W K+ + N EI + + L ++ D G Y +N AGS C + +
Sbjct: 31825 TLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQ 31884
Query: 1113 IK 1118
++
Sbjct: 31885 VE 31886
Score = 96.3 bits (238), Expect = 9e-20
Identities = 89/344 (25%), Positives = 136/344 (39%), Gaps = 36/344 (10%)
Frame = +3
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS 1106
Q V WY ++ + EIT+++ +L VK + D G Y CKV ND G +
Sbjct: 31596 QSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAE 31655
Query: 1107 IVIKEPK-------------------------KPPVFDQHLTPVTVSEGEFLQLSCHVRG 1211
+ +K + +PP F L T GE ++ +
Sbjct: 31656 LFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITV 31715
Query: 1212 SEPIRIQWLKAGREIKPSD---RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
+ W K+G++IKP D + +F G L VT D +Y A N G D+
Sbjct: 31716 HPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS 31775
Query: 1383 SKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWT 1562
K+K+T +L +E Q E + F +V G P P +KW
Sbjct: 31776 CKAKLTVTLHPPPTDSTLRPMFK-RLLANAECQ-----EGQSVCFEIRVSGIPPPTLKWE 31829
Query: 1563 KGKWRQLNQGGRI-FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV--- 1730
K + L+ G I IH+ D L IRDT D+G YR A N G +LQV
Sbjct: 31830 KDG-QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERL 31888
Query: 1731 ----NERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEIDIMELLK 1850
E K +E+ E ++ + KT + + E + + ++ K
Sbjct: 31889 RYKKQEFKSKEEHERHVQKQIDKTLRMAEILSGTESVPLTQVAK 31932
Score = 95.5 bits (236), Expect = 2e-19
Identities = 151/607 (24%), Positives = 238/607 (39%), Gaps = 10/607 (1%)
Frame = +3
Query: 15 TVGDS--ASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
TV +S A +C++A P+ W + L T + + L+ +D GE
Sbjct: 2630 TVAESQEAVFECEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGE 2688
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y + S +S L V+ K+ + L+++ T VF ++ V W
Sbjct: 2689 YTYKVATS----KTSAKLKVEAVKI----KKTLKNLTVTETQDAVFTVELTHPNVKGVQW 2740
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQ---TDRSFAGQYSCTATNPIGSASSSARLILT 539
K+G L+ S + +L I D S G +G +SARL +
Sbjct: 2741 IKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFR-------LGRLGASARLHVE 2793
Query: 540 EGRNPPFFDIPLAPVDAVVGESAD--FECHVT-GTQPIKVAWAKDNREIRSGGNYQISYL 710
+ I P D E+A FE V+ T P+K W + EI+ +++
Sbjct: 2794 TVK------IIKKPKDVTALENATVAFEVSVSHDTVPVK--WFHKSVEIKPSDKHRLVSE 2845
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET-VEETE 887
L + + D G+YT VG+ C A+L ++ I TK + V ET+
Sbjct: 2846 RKVHKLMLQNISPSDAGEYTAV----VGQLECKAKLFVETLHI----TKTMKNIEVPETK 2897
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
SF E + W KN VEI + +I + L + S D+ YT
Sbjct: 2898 TASFECE---VSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV 2954
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
ND SA T + P + L + E + + V E I +WLK G
Sbjct: 2955 CGNDQVSATLTVT--------PIMITSMLKDINAEEKDTITFEVTVN-YEGISYKWLKNG 3005
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
EIK +D+C T L ++V DA DY + VAG TS + +
Sbjct: 3006 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADY----TFVAGKATSTATL---------- 3051
Query: 1428 XXXXXXVDGK-LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIF 1604
V+ + + F + I+V+EK A F +V +P V+W K ++L RI
Sbjct: 3052 -----YVEARHIEFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDD-QELQITDRIK 3104
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLK 1784
I ++ +L I T +D+G Y VA G S L V R + +R++ K
Sbjct: 3105 IQKEKYVHRLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVEGRDVR------IRSIKK 3154
Query: 1785 KTPVLKK 1805
+ V++K
Sbjct: 3155 EVQVIEK 3161
Score = 93.2 bits (230), Expect = 8e-19
Identities = 87/310 (28%), Positives = 129/310 (41%), Gaps = 38/310 (12%)
Frame = +3
Query: 72 VSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVSSSTFL--- 242
V+WY G +L + Y++ + + VA L + D G Y C+ N GE SS L
Sbjct: 31600 VTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVK 31659
Query: 243 ----------------------TVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
T++ + PP F+ L + VG V F ++
Sbjct: 31660 GVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEP 31719
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDN-----VATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
V+W+K G+ +K G N + ++ T+N TD +Y+ A N G S
Sbjct: 31720 HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDD--AEYTVVARNKYGEDSCK 31777
Query: 522 ARLILTEGRNP------PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRS 683
A+L +T P P F LA + G+S FE V+G P + W KD + +
Sbjct: 31778 AKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSL 31837
Query: 684 GGNYQISY--LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK 857
G N +I + L+ A L I DTG Y A N G SC A L + ERL + K
Sbjct: 31838 GPNIEIIHEGLDYYA-LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV-ERL---RYKK 31892
Query: 858 KLSETVEETE 887
+ ++ EE E
Sbjct: 31893 QEFKSKEEHE 31902
Score = 88.2 bits (217), Expect = 3e-17
Identities = 65/182 (35%), Positives = 82/182 (45%), Gaps = 11/182 (6%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRP---TATYKMHFRNNVATLVFNQVDSNDSGE 188
VG++ + PE V+WYK K++P Y + L N V ++D E
Sbjct: 31703 VGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAE 31762
Query: 189 YICRAENSVGEVSSSTFLTVQ------EQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
Y A N GE S LTV + L P F R L + + G V FE VSG
Sbjct: 31763 YTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIP 31822
Query: 351 PISVSWFKDGRPLKDGPNIQT--SFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
P ++ W KDG+PL GPNI+ LD A L+I T G Y TATN GS S A
Sbjct: 31823 PPTLKWEKDGQPLSLGPNIEIIHEGLDYYA-LHIRDTLPEDTGYYRVTATNTAGSTSCQA 31881
Query: 525 RL 530
L
Sbjct: 31882 HL 31883
Score = 87.0 bits (214), Expect = 6e-17
Identities = 115/545 (21%), Positives = 200/545 (36%), Gaps = 47/545 (8%)
Frame = +3
Query: 249 QEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFL-D 425
+ + + F ++++ + G+ V F C +SG ++W+KDG+ +K G Q FL D
Sbjct: 1285 ESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1344
Query: 426 NVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR--NPPFFDIPLAPVDAVVG 599
A+L I G Y+ A+N G+A S +L + P + L PV +
Sbjct: 1345 GRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRS 1404
Query: 600 ESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYA 779
S PI+++ A+ + S + + L
Sbjct: 1405 LSP----RSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRL----------------- 1443
Query: 780 VNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNN 959
+++ +QL ERL P F K + + EG + R + +V G W+ +
Sbjct: 1444 -----EETDESQL---ERLYKPVFVLK-PVSFKCLEGQTARFDLKVVGRPMPETFWFHDG 1494
Query: 960 VEIHPTANCEITFKNNALL-LQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIK--EPKK 1130
+I ++ K + L + A+ D+G +T N AG + + + ++ E +
Sbjct: 1495 QQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQV 1554
Query: 1131 PPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS--DRCSFSFANGTAV 1304
P+F + L V + EG L++ G+ I WLK I P + G A
Sbjct: 1555 KPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAA 1614
Query: 1305 LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV------------ 1448
L+ D+ Y A N AG DT++ KV +
Sbjct: 1615 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAA 1674
Query: 1449 ----------------DGKLFFVSEPQSIRVVEKTTATFIAKVG-----------GDPIP 1547
+G L+ + Q +K T+ + + G GDP
Sbjct: 1675 PELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTM 1734
Query: 1548 NVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
V+W + L R+ + + L+ DSG+ C A NK+G ++ L
Sbjct: 1735 VVEWLH-DGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1793
Query: 1728 VNERK 1742
V + K
Sbjct: 1794 VKDEK 1798
Score = 87.0 bits (214), Expect = 6e-17
Identities = 114/484 (23%), Positives = 184/484 (38%), Gaps = 7/484 (1%)
Frame = +3
Query: 243 TVQEQKLPPSFSRQLRDV----QETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQ 410
T Q + +P F ++++D+ E VG +FEC VS S I+ +W KDG +++ P +
Sbjct: 11107 TYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAIT-TWMKDGSNIRESPKHR 11165
Query: 411 TSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDA 590
L+I S AG+Y+C +S+A+L++ E F V
Sbjct: 11166 FIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEE-LPVRFVKTLEEEVTV 11224
Query: 591 VVGESADFECHVTGTQPIKVAWAKDNR-EIRSGGNYQISYLENSAHLTILKVDKGDTGQY 767
V G+ C + + V W KD + + G + LTI D D G Y
Sbjct: 11225 VKGQPLYLSCELNKER--DVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTY 11282
Query: 768 TCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAW 947
T V C++ + + E +I K + + + +G + +A P ++ W
Sbjct: 11283 T-VTVENANNLECSSCVKVVE-VIRDWLVKPIRDQHVKPKGTAI-FACDIAKDTP-NIKW 11338
Query: 948 YKNNVEI--HPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKE 1121
+K EI P EI N L L++K A D Y ++ A T E
Sbjct: 11339 FKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVE 11398
Query: 1122 PKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTA 1301
KP + VT+ E E + ++ I QW G ++PS C G
Sbjct: 11399 LLKP------IEDVTIYEKESASFDAEISEAD-IPGQWKLKGELLRPSPTCEIKAEGGKR 11451
Query: 1302 VLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQ 1481
L V AG+ + +A N + K + +L F +
Sbjct: 11452 FLTLHKVKLDQAGEVLYQALNAITTAILTVK------------------EIELDFAVPLK 11493
Query: 1482 SIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTD 1661
+ V E+ A F + + NV W+KG + + I G + L I D+ D
Sbjct: 11494 DVTVPERRQARFECVLTRE--ANVIWSKGP-DIIKSSDKFDIIADGKKHILVINDSQFDD 11550
Query: 1662 SGLY 1673
G+Y
Sbjct: 11551 EGVY 11554
Score = 84.7 bits (208), Expect = 3e-16
Identities = 97/450 (21%), Positives = 162/450 (36%), Gaps = 72/450 (16%)
Frame = +3
Query: 264 PPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLN 443
PP+ L++V G V EC +SG +V+W+++ ++ + Q +F +A L
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001
Query: 444 IFQTDRSFAGQYSCTATNPIGSASSSARLIL------------------------TEGRN 551
I + +G+++C+A N G+ S+S L + E R+
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRD 1061
Query: 552 PPFFDIPLAPVDA-------------------VVGESADFECHVTGTQPIKVAWAKDNRE 674
D L A V G S F C V G V W K
Sbjct: 1062 VVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVP 1121
Query: 675 IRSGGNYQISYLENSAH--LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPS 848
+ +G Y++SY + + L I D G+YT N+ G+ S +A L E
Sbjct: 1122 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL--LEEADYEL 1179
Query: 849 FTKKLSETVEETEGNSFRLEGRVAGSQP--------------------------ISVAWY 950
K E + +T+ +F E +V + P + V Y
Sbjct: 1180 LMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTY 1239
Query: 951 KNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKK 1130
+ E H ++ E K + ++ K ++ + + D + + +
Sbjct: 1240 VEDQEFHISSFEERLIKE--IEYRIIKTTLEEL------LEEDGEEKMAVD--ISESEAV 1289
Query: 1131 PPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSF-ANGTAVL 1307
FD + + EG + C + G +I W K G+ IK +R F +G A L
Sbjct: 1290 ESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASL 1349
Query: 1308 EFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
V D G Y ASN+ G+ K+
Sbjct: 1350 RIPVVLPEDEGIYTAFASNIKGNAICSGKL 1379
Score = 80.1 bits (196), Expect = 7e-15
Identities = 83/372 (22%), Positives = 143/372 (38%), Gaps = 13/372 (3%)
Frame = +3
Query: 309 GLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCT 488
G +V + ++G+ V W +G L + + + TL I Q G +C
Sbjct: 33053 GQRLVLKANIAGAT--DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCI 33110
Query: 489 ATNPIGSASSSARLILTEGRN--PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAK 662
+ G L L++ + P F P + + G++ F C ++G ++ W K
Sbjct: 33111 SKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQ-NINEGQNVLFTCEISGEPSPEIEWFK 33169
Query: 663 DNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP 842
+N I N IS N L I D+G+YT A N G+ S TA L + +
Sbjct: 33170 NNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEE 33229
Query: 843 PSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQ 1022
PS E V T G++ L+G + SQ + ++ K ++ +
Sbjct: 33230 PS-----REVVLRTSGDT-SLQGSFS-SQSVQMSASKQEASFSSFSSSSASSMTEMKFAS 33282
Query: 1023 VKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKK---------PPVFDQHLTPVTVSE 1175
+ SM ++S+ + + + + K PP + + +++ E
Sbjct: 33283 MSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDE 33342
Query: 1176 GEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFAN--GTAVLEFKDVTKADAGDYV 1349
G+ L ++C G + W GR+I ++ F N L DV K D G Y
Sbjct: 33343 GKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYT 33402
Query: 1350 CKASNVAGSDTS 1385
N GSD++
Sbjct: 33403 LSLGNEFGSDSA 33414
Score = 78.6 bits (192), Expect = 2e-14
Identities = 85/384 (22%), Positives = 148/384 (38%), Gaps = 13/384 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ + G L+ +AG + V W +L + Y+ + TL Q D G
Sbjct: 33048 MSINEGQRLVLKANIAGATD--VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 33105
Query: 186 EYICRAENSVGEVSSSTFLTV-QEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
C ++ G V LT+ +E P+F Q R G V+F C +SG +
Sbjct: 33106 ILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEI 33165
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WFK+ P+ N+ S NV +L I S +G+Y+ A N G S++A L++
Sbjct: 33166 EWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL- 33224
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVT-GTQPIKVAWAKDNREIRSGGNYQISYLE-- 713
P + P V V+ S D + +Q ++++ +K S + S +
Sbjct: 33225 ----PLVEEPSREV--VLRTSGDTSLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEM 33278
Query: 714 -----NSAHLTILKVDKGDTGQYTCYAVNEVG--KDSCTAQLNIKERLIPPSFTKKLSET 872
++ ++ ++ + + ++ + + S + L R IPP + L
Sbjct: 33279 KFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRGIPPKI-EALPSD 33337
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKN--NALLLQVKKASMGD 1046
+ EG + G V W +IH +N + L + D
Sbjct: 33338 ISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQD 33397
Query: 1047 AGLYTCKVSNDAGSALCTSSIVIK 1118
GLYT + N+ GS T +I I+
Sbjct: 33398 GGLYTLSLGNEFGSDSATVNIHIR 33421
Score = 78.2 bits (191), Expect = 3e-14
Identities = 51/180 (28%), Positives = 94/180 (52%), Gaps = 3/180 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATY---KMHFRNNVATLVFNQVDSN 176
V V G +A+ + ++G P VSW++ D ++ T+T ++ F + A L V
Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSWFR-DGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
+SG Y +A N G+ +S+ L V+ + PP+F ++L+ + G V + V+G
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTP 133
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
V +++DG ++ + Q S ++ +L I + +G YS ATN +G A+S+A L++
Sbjct: 134 VVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 77.8 bits (190), Expect = 3e-14
Identities = 68/260 (26%), Positives = 107/260 (41%), Gaps = 32/260 (12%)
Frame = +3
Query: 1113 IKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFAN 1292
++ P PP L VTV EGE + L CH+ G + W + +I+ S +F +
Sbjct: 936 VEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQS 995
Query: 1293 GTAVLEFKDVTKADAGDYVCKASNVAGS---------------DTSKSKVTXXXXXXXXX 1427
G A L ++ D+G + C A N AG+ + + VT
Sbjct: 996 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1055
Query: 1428 XXXXXXV---DGKL-------------FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW 1559
V D L +F+++P ++VE + F +VGG+P P+V W
Sbjct: 1056 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1115
Query: 1560 TK-GKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
K G ++ +++ E KL I T D+G Y V NKHGE ++ +L E
Sbjct: 1116 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLL--E 1173
Query: 1737 RKKQEKIEGDLRAMLKKTPV 1796
E + + ML +T V
Sbjct: 1174 EADYELLMKSQQEMLYQTQV 1193
Score = 77.4 bits (189), Expect = 5e-14
Identities = 123/532 (23%), Positives = 204/532 (38%), Gaps = 34/532 (6%)
Frame = +3
Query: 246 VQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLD 425
V E + P+FS VQ VG + E +SG +++W KDG PLK I +
Sbjct: 23227 VIEPDVKPAFSSY--SVQ--VGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSL 23282
Query: 426 NVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGES 605
++ TL+I +T + GQY T N +G ++S ++ + +PP + V A
Sbjct: 23283 DLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSA----- 23337
Query: 606 ADFECHVTGTQPIKVAWAKDNREIRSGG----NYQISYLENSAHL----------TILKV 743
+ I ++W N + +GG NY + + + + T LKV
Sbjct: 23338 ----------ESITLSW---NPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKV 23384
Query: 744 DKGDTG---QYTCYAVNEVGK------DSCTAQLNIKERLIP----PSFTKKLSETVEET 884
K TG Q+ +A N G+ D AQ KE P + K S ++
Sbjct: 23385 TKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWH 23444
Query: 885 E----GNSFRLEGRVAGSQPISVAWYK-NNVEIHPTANCEITFKNNALLLQVKKASMGDA 1049
E G S + + + S+ W K N IH T FK L ++ +
Sbjct: 23445 EPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDT-----QFKAQNL----EEGIEYEF 23495
Query: 1050 GLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEF-LQLSCHVRGSEPIR 1226
+Y + ++ + V ++P PP + P+ V E LQ + V +
Sbjct: 23496 RVYAENIVGVGKASKNSECYVARDPCDPPGTPE---PIMVKRNEITLQWTKPVYDGGSMI 23552
Query: 1227 IQWLKAGREIKPSDRCSFSFANGTAV-LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTX 1403
++ R++ SF N +T+ ++ A N AG+ + S T
Sbjct: 23553 TGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTG 23612
Query: 1404 XXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQL 1583
+D K +I V T A V G P+P ++W +G +++
Sbjct: 23613 PITAKDEVELPRISMDPKF-----RDTIVVNAGETFRLEADVHGKPLPTIEWLRGD-KEI 23666
Query: 1584 NQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
+ R I +A L ++D + D G Y A N G VN++V +R
Sbjct: 23667 EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR 23718
Score = 75.1 bits (183), Expect = 2e-13
Identities = 129/563 (22%), Positives = 208/563 (36%), Gaps = 48/563 (8%)
Frame = +3
Query: 186 EYICRAENSVG-------EVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSG 344
E+ AEN G +S T LT E P ++++DV +G C + G
Sbjct: 30502 EFRVFAENETGLSRPRRTAMSIKTKLTSGEA---PGIRKEMKDVTTKLGEAAQLSCQIVG 30558
Query: 345 SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
+ W++ G+ L + S TL + ++ G Y+C ATN +G +S+
Sbjct: 30559 RPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSS 30618
Query: 525 RLILTEGRNPPFFDIPLAPVD----AVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
+L+L P F P P+ VG + G + W + +++ N
Sbjct: 30619 KLLLQ--ATPQFH--PGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSEN 30674
Query: 693 YQISYLENSAHLTILKVD-KGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE 869
I E+ HL + V K G+Y N G + I+++ P+ +
Sbjct: 30675 ITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEA 30734
Query: 870 TVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDA 1049
++ + S++ GS W N V CE K A V A
Sbjct: 30735 LLKNSAVISWKPPADDGGS------WITNYV----VEKCEA--KEGAEWQLVSSA----I 30778
Query: 1050 GLYTCKVSN---DAG-----SALCT----------SSIVIKEPKKPPVFDQHLTPVTVSE 1175
+ TC++ N +AG SA T S ++IK P + P T V++
Sbjct: 30779 SVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTK 30838
Query: 1176 GEFLQLSCHVR-------GSEPIRIQWLKAGREIKPSDRCS----------FSFANGTAV 1304
SC V G IR +L+ RE K + S FS N
Sbjct: 30839 D-----SCVVAWKPPASDGGAKIRNYYLEK-REKKQNKWISVTTEEIRETVFSVKNLIEG 30892
Query: 1305 LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS 1484
LE++ K + + S ++ T KS V F E ++
Sbjct: 30893 LEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAP----------------HFKEELRN 30936
Query: 1485 IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ-KGDEAKLEIRDTTKTD 1661
+ V ++ AT + KV G P P VKW + + G + I + KG +L I T D
Sbjct: 30937 LNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDD 30996
Query: 1662 SGLYRCVAFNKHGEIESNVNLQV 1730
+ +Y+ A N+ G + +L+V
Sbjct: 30997 ATVYQVRATNQGGSVSGTASLEV 31019
Score = 75.1 bits (183), Expect = 2e-13
Identities = 70/287 (24%), Positives = 110/287 (38%), Gaps = 35/287 (12%)
Frame = +3
Query: 636 QPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQ 815
Q +V W R++ + Y+I+Y + A L + + K D G Y C VN+ G+DS A+
Sbjct: 31596 QSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAE 31655
Query: 816 LNIK-----------------------ERLI--PPSFTKKLSETVEETEGNSFRLEGRVA 920
L +K RL+ PP FT L G + R +
Sbjct: 31656 LFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYV-GENVRFGVTIT 31714
Query: 921 GSQPISVAWYKNNVEIHPTAN-CEITFKNNALLLQ--VKKASMGDAGLYTCKVSNDAGSA 1091
V WYK+ +I P N + TF+++ L Q + + D YT N G
Sbjct: 31715 VHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGED 31774
Query: 1092 LCTSSIVIKEPKKP------PVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
C + + + P P+F + L EG+ + V G P ++W K G+
Sbjct: 31775 SCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQP 31834
Query: 1254 IKPSDRCSFSFAN-GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS 1391
+ L +D D G Y A+N AGS + ++
Sbjct: 31835 LSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQA 31881
Score = 74.3 bits (181), Expect = 4e-13
Identities = 97/457 (21%), Positives = 174/457 (38%)
Frame = +3
Query: 30 ASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAEN 209
A+ +C+ + P + V WYK ++ Y+MH V L +D++D+ +Y C
Sbjct: 2192 ATFECETS-EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVL-- 2248
Query: 210 SVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPL 389
V + + T + + F ++L+D++ EC VS E I W+ + L
Sbjct: 2249 -VEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVS-PENIEGKWYHNDVEL 2306
Query: 390 KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDI 569
K + L + + G+YS I ++ +L + P
Sbjct: 2307 KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFV----IDGKKTTCKLKMKP--RPIAILQ 2360
Query: 570 PLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDK 749
L+ G+ E V+ + ++ W KD +E++ I + S L I + K
Sbjct: 2361 GLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTK 2419
Query: 750 GDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQ 929
D G Y+ + + +G + +I P + V EG LE +V+
Sbjct: 2420 EDAGNYS-FTIPALGLSTSGRVSVYSVDVITP------LKDVNVIEGTKAVLECKVSVPD 2472
Query: 930 PISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSI 1109
SV WY N+ +I P + K L + + D G Y V G ++
Sbjct: 2473 VTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIV----GRVETNCNL 2528
Query: 1110 VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFA 1289
+++ K + L +T +E + + + S I + W +EIKPS +
Sbjct: 2529 SVEKIK----IIRGLRDLTCTETQNVVFEVELSHS-GIDVLWNFKDKEIKPSSKYKIEAH 2583
Query: 1290 NGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
L ++ K D G Y + AG + + K+T
Sbjct: 2584 GKIYKLTVLNMMKDDEGKY----TFYAGENMTSGKLT 2616
Score = 72.8 bits (177), Expect = 1e-12
Identities = 129/577 (22%), Positives = 220/577 (38%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+V VG++A + +L+ P++ W L + ++ L+ + +G
Sbjct: 11760 VEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTG 11818
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
E +A N+ S+ L V+E LP F L DV+ FEC VS EP +
Sbjct: 11819 EVSFQAANA----KSAANLKVKE--LPLIFITPLSDVKVFEKDEAKFECEVS-REPKTFR 11871
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W K + + + ++ I +Y A + +S +LI+ EG
Sbjct: 11872 WLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDK----HTSGKLII-EG 11926
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
F PL V A ESA F ++ I+V W K+++ + + + + +
Sbjct: 11927 IRLKFLT-PLKDVTAKEKESAVFTVELSHDN-IRVKWFKNDQRLHTTRSVSMQDEGKTHS 11984
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
+T + DT Q A+ S A+L + E P FT KL + E + L
Sbjct: 11985 ITFKDLSIDDTSQIRVEAMGM----SSEAKLTVLEG--DPYFTGKLQDYTG-VEKDEVIL 12037
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+ ++ + V W+K+ EI P+ N I +L +KKA D G YTC D G
Sbjct: 12038 QCEISKADA-PVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCG 12092
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
+ + + I++ + V H V V E E + + + I W G + +
Sbjct: 12093 TDKTSGKLDIEDREIKLVRPLH--SVEVMETETARFETEI-SEDDIHANWKLKGEALLQT 12149
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
C L + G +A+NV S + K
Sbjct: 12150 PDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRV-------------- 12195
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
+ + + + V TATF ++ + IP + KGK +L ++ +G
Sbjct: 12196 ----IGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGK--KLEPSDKVVPRSEGKV 12249
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
L +RD D+G + A + +++ NL V E
Sbjct: 12250 HTLTLRDVKLEDAGEVQLTA----KDFKTHANLFVKE 12282
Score = 72.0 bits (175), Expect = 2e-12
Identities = 138/669 (20%), Positives = 222/669 (33%), Gaps = 58/669 (8%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNN-VATLVFNQVDSNDSG 185
K G +A ++ G P W+ ++ T+K+ + + +L+ +DSG
Sbjct: 1467 KCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSG 1526
Query: 186 EYICRAENSVGEVSSSTFLTVQ--EQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
E+ A+N G S S LTV+ E ++ P F +L++V G + + +G+
Sbjct: 1527 EWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPD 1586
Query: 360 VSWFKDGRPL--KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASS----- 518
+ W K+ + P I+ A L I T + Y+ TA N G ++
Sbjct: 1587 IVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVN 1646
Query: 519 ----------SARLILTEG----------------------------------RNPPFFD 566
+LI+ G + PFF
Sbjct: 1647 VEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFK 1706
Query: 567 IPLAPVDAVVGESADFECHVT--GTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
L + A FEC +T G + V W D + + + ++ L
Sbjct: 1707 KKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGV 1766
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
D+G TC A N+ G D +A L +K+ K L E + EG
Sbjct: 1767 AYSRDSGIITCRATNKYGTDHTSATLIVKDE-------KSLVEESQLPEGRK-------- 1811
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G Q I ++ A T
Sbjct: 1812 GLQRIE------------------------------------------ELERMAHEGALT 1829
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSF 1280
++ K+ P + PV V EGE + C V G ++ W G+ I+ S R
Sbjct: 1830 GVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV 1889
Query: 1281 SFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKL 1460
+ +G L+ D D G+ A N G K K+
Sbjct: 1890 RY-DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPE 1948
Query: 1461 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEI 1640
F V EP ++ F + P+ + TK + +L + RI H+K E E+
Sbjct: 1949 FHVHEPGKLQ--------FEVQKVDRPVDTTE-TK-EVVKLKRAERI-THEKVPEESEEL 1997
Query: 1641 RDTTK--TDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAG 1814
R K T+ G Y E+ +++ RKK E E LR + K
Sbjct: 1998 RSKFKRRTEEGYY-----------EAITAVELKSRKKDESYEELLRKTKDELLHWTKELT 2046
Query: 1815 EEEEIDIME 1841
EEE+ + E
Sbjct: 2047 EEEKKALAE 2055
Score = 70.9 bits (172), Expect = 4e-12
Identities = 108/437 (24%), Positives = 163/437 (37%), Gaps = 26/437 (5%)
Frame = +3
Query: 165 VDSNDSGEYICRAENSVG---------EVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLP 317
+D N E+ A+N VG + L E L S R+L V+ G P
Sbjct: 18567 LDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASM-RKLVIVR--AGCP 18623
Query: 318 VVFECAVSGSEPISVSWFKDG--RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTA 491
+ V G V+W K G ++ G Q +D +A L I + R +G+YS T
Sbjct: 18624 IRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDLVDTMAFLVIPNSTRDDSGKYSLTL 18680
Query: 492 TNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVT--------GTQPIK 647
NP G + N D P D V + CHV+ G+Q
Sbjct: 18681 VNPAGEKAVFV--------NVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTH 18732
Query: 648 VAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCT---AQL 818
K + ++ + S H+T L G+ + AVNE G T +
Sbjct: 18733 YIVEKREADRKTWSTVTPEVKKTSFHVTNLV--PGNEYYFRVTAVNEYGPGVPTDVPKPV 18790
Query: 819 NIKERLIPPSFTKKLSETVEETEGNSFR--LEGRVAGSQPISVAWYKNNVEIHPTANCEI 992
+ L P +KL E E T+ ++ L G I E P
Sbjct: 18791 LASDPLSEPDPPRKL-EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTE 18849
Query: 993 TFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP--VT 1166
L L V G + N G +L + + E K+ + + L P +T
Sbjct: 18850 YSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQIT 18909
Query: 1167 VSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDY 1346
+ G+ L++ HV G +W K E+ S + A+ +++L KDVT+ D+G Y
Sbjct: 18910 IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYY 18969
Query: 1347 VCKASNVAGSDTSKSKV 1397
A N +G+DT K KV
Sbjct: 18970 SLTAENSSGTDTQKIKV 18986
Score = 67.8 bits (164), Expect = 4e-11
Identities = 90/409 (22%), Positives = 150/409 (36%), Gaps = 31/409 (7%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ V G + ++G P V+W + L AT + ++ ++V + G
Sbjct: 16534 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQG 16591
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y A+N GE + + V DV VG P + + E ++
Sbjct: 16592 VYSLLAKNEAGERKKTIIVDVL-------------DVPGPVGTPFLAHNLTN--ESCKLT 16636
Query: 366 WFKD----GRPLKD-------------GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTAT 494
WF G P+ + P T N + Q F + A
Sbjct: 16637 WFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYF---FRIAAE 16693
Query: 495 NPIGSA---SSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIK------ 647
N IG +S L++ E +P P D V E +T P
Sbjct: 16694 NSIGMGPFVETSEALVIREP-----ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEI 16748
Query: 648 VAWAKDNREIRSGGNYQISYLEN--SAHLTILKVDKGDTGQYTCYAVNEVGKDS---CTA 812
+ + ++R I + ++++ +N S T+ + +GDT +Y AVN VG+ CT
Sbjct: 16749 INYVLESRLIGTEKFHKVTN-DNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTK 16807
Query: 813 QLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEI 992
+ K+ L PP+ + + G +F L GR +G V+W+K+ ++ I
Sbjct: 16808 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 16867
Query: 993 TFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPV 1139
L L+ KA D+G Y V N GS + + + PPV
Sbjct: 16868 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPV 16916
Score = 67.4 bits (163), Expect = 5e-11
Identities = 58/201 (28%), Positives = 81/201 (40%), Gaps = 2/201 (0%)
Frame = +3
Query: 1134 PVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS--DRCSFSFANGTAVL 1307
P FAADAGEYQCRVTNEVGSSTCSARVTLRE---PPSFIKKI-EATSSLRGGTAAFQ 4512
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+ GS PI+V W K+N EI N +TF+NN L + + G Y C+ NDAG
Sbjct: 4513 ATLKGSLPITVTWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGI 4572
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
C++ + +KE P + + V++G+ L G++ I +W K G+E+
Sbjct: 4573 QRCSALLSVKE---PATIMEEAVSIDVTQGDPATLQVKFSGTKEISAKWFKDGQELTLGP 4629
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ S + ++L+ K D+G+Y + N G + K+ + V
Sbjct: 4630 KYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKASIN---------------V 4674
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFI----AKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
+ S + +R ++ +FI G PI +++W K ++++ +
Sbjct: 4675 LDLIIPPSFTKKLRKMDSIKGSFIDLECIVAGSHPI-SIQWFKDD-QEISASDKHKFSFH 4732
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ A LEI TDSG Y C A NK G + + +L V E
Sbjct: 4733 DNTAFLEISQLEGTDSGTYTCSATNKAGHSQCSGHLTVKE 4772
Score = 220 bits (561), Expect = 3e-57
Identities = 158/604 (26%), Positives = 257/604 (42%), Gaps = 26/604 (4%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV V G A ++G P+ +SWYK + L K TL+ + D+
Sbjct: 3253 PVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDA 3312
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKL----------PPSFSRQLRDVQETVGLPVVFEC 332
Y C A+N G ++S L+V+ ++ PP+ L+D + G P F+C
Sbjct: 3313 AVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIVTPLQDTVTSEGRPARFQC 3372
Query: 333 AVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSA 512
VSG++ + VSW+ + +K + + ++ L I + G Y+ A N +G
Sbjct: 3373 QVSGTD-LKVSWYCKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYAFVANNAVGQV 3431
Query: 513 SSSARLILT----------------EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPI 644
SS+A L L E + P + P++ +G A F C + G +
Sbjct: 3432 SSTATLRLEAPESILHERIGQQIEMEMKAAPVIKRRIEPLEVALGHLAKFTCEIQGAPNV 3491
Query: 645 KVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI 824
+ W K REI I + L IL+ D G+YTC A NE G SCTA L +
Sbjct: 3492 RFQWFKAGREIYESDKCSIRSSNYVSSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 3551
Query: 825 KERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKN 1004
E PP+F + + + G + + V+G+ I + W K+ + P+ +C +T +
Sbjct: 3552 TEAY-PPTFLSR-PKALTTFVGKAAKFLCTVSGTPVIEIIWQKDGAALSPSPDCRVTDAD 3609
Query: 1005 NALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEF 1184
N L++ ++ D G+Y+CK SN G+ +C + + I + P F + L V + +
Sbjct: 3610 NKHSLELSNLTVQDRGIYSCKASNKFGADICQAELTIIDK---PHFIKELEAVQSAINKK 3666
Query: 1185 LQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASN 1364
+ L C V + I W K G+++ F + A LE D+G Y C ASN
Sbjct: 3667 IHLECQVDEDRKVTITWSKDGQKLPAGKDYKIYFEDKIASLEIPLAKLKDSGTYTCTASN 3726
Query: 1365 VAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPI 1544
AGS +S + V + F S ++ +A K+ G P+
Sbjct: 3727 EAGSSSSSAAVAVR--------------EPPSFVKKVDPSYLMLPGESARLHCKLKGSPV 3772
Query: 1545 PNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNL 1724
V W K ++L++ + + EA L+I D DSG Y C A N G + +
Sbjct: 3773 IQVTWFKNN-KELSESNTVRMSFVNSEAILDITDVKVDDSGTYSCEATNDVGSDSCSTEV 3831
Query: 1725 QVNE 1736
+ E
Sbjct: 3832 VIKE 3835
Score = 175 bits (443), Expect = 1e-43
Identities = 151/640 (23%), Positives = 276/640 (43%), Gaps = 30/640 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+KV A +C+++ P+I V W K +L+ K+ V L+ +D+G
Sbjct: 3073 IKVLEKKRAMFECEVS-EPDITVQWMKDGQELQIADRIKIQKEKYVHRLLIPSTRMSDAG 3131
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y A G +S++ S ++++ +++ + V FE + +
Sbjct: 3132 KYTVVAG---GNMSTANLFVEGRDVRIRSIKKEVQVIEKQRAV-VEFEV---NEDDVDAH 3184
Query: 366 WFKDGRPLKDGPNIQTSFL--DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
W+KDG + + ++ + + I +T S AG+Y+ A G SS L +
Sbjct: 3185 WYKDGIEINFQVQERHQYVVERRIHRMFISETRHSDAGEYTFVA----GRNRSSVTLYVN 3240
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
PP L PV G+ A F ++G K++W K+ + + +G ++ +L +
Sbjct: 3241 -APEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTG--FKCKFLHDG 3297
Query: 720 AHLTILKVDK--GDTGQYTCYAVNEVGKDSCTAQLNIKERLI----------PPSFTKKL 863
T+L ++ D YTC A N+ G + +A L+++ + PP+ L
Sbjct: 3298 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIVTPL 3357
Query: 864 SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMG 1043
+TV +EG R + +V+G+ + V+WY + +I P+ +T + L++ +A
Sbjct: 3358 QDTVT-SEGRPARFQCQVSGTD-LKVSWYCKDKKIKPSRFFRMTQFEDTYQLEIAEAYPE 3415
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEP----------------KKPPVFDQHLTPVTVSE 1175
D G Y +N G T+++ ++ P K PV + + P+ V+
Sbjct: 3416 DEGTYAFVANNAVGQVSSTATLRLEAPESILHERIGQQIEMEMKAAPVIKRRIEPLEVAL 3475
Query: 1176 GEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCK 1355
G + +C ++G+ +R QW KAGREI SD+CS +N + LE D G+Y CK
Sbjct: 3476 GHLAKFTCEIQGAPNVRFQWFKAGREIYESDKCSIRSSNYVSSLEILRTQVVDCGEYTCK 3535
Query: 1356 ASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGG 1535
ASN GS + + +T F+S P+++ A F+ V G
Sbjct: 3536 ASNEYGSVSCTATLTVTEAYPPT-------------FLSRPKALTTFVGKAAKFLCTVSG 3582
Query: 1536 DPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESN 1715
P+ + W K L+ + ++ LE+ + T D G+Y C A NK G
Sbjct: 3583 TPVIEIIWQK-DGAALSPSPDCRVTDADNKHSLELSNLTVQDRGIYSCKASNKFGADICQ 3641
Query: 1716 VNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEIDI 1835
L + ++ K +++ + K L+ E+ ++ I
Sbjct: 3642 AELTIIDKPHFIKELEAVQSAINKKIHLECQVDEDRKVTI 3681
Score = 132 bits (331), Expect = 1e-30
Identities = 161/606 (26%), Positives = 240/606 (39%), Gaps = 11/606 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT G++A+ C+L+ +I V WY KL P V TL V D+G
Sbjct: 12248 VTVTAGETATFDCELS-YEDIPVEWYLKGKKLEPNDKVVTRSEGRVHTLTLRDVKLEDAG 12306
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
E A+ + + L V+E P F++ L D V EC VS E V
Sbjct: 12307 EVQLTAK----DFKTQANLFVKEP--PVEFTKPLEDQTVEEEATAVLECEVS-RENAKVK 12359
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFK+G + + V L I Y+C A + +S L +
Sbjct: 12360 WFKNGTEILKSKKYEIVADGRVRKLIIHGCTPEDIKTYTCDAKD----FKTSCNLNVV-- 12413
Query: 546 RNPPFFDI--PLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
PP + PL + E+A FEC ++ KV W KD EI+ G Y I
Sbjct: 12414 --PPHVEFLRPLTDLQVKEKETARFECEISKENE-KVQWFKDGAEIKKGKKYDIISKGAV 12470
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I K D +Y+C EV + L + E FTK L+ +E +EG++
Sbjct: 12471 RILVINKCLLNDEAEYSC----EVRTARTSGMLTVLEE--EAVFTKNLAN-LEVSEGDTI 12523
Query: 900 RLEGRVAGSQP-ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV-S 1073
+L V S+P V WYK + EI T EI +L ++ A + DAG Y C++ S
Sbjct: 12524 KLVCEV--SKPGAEVIWYKGDEEIIETGRFEILTDGRKRILIIQNAQLEDAGSYNCRLPS 12581
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
+ S + + + KP Q+L + EGE + C + E +QW + +
Sbjct: 12582 SRTDSKVKVHELAAEFISKP----QNL---EILEGEKAEFVCTI-SKESFEVQWKRDDQT 12633
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
++ D+ VL KD T D G YV + G+ + + +T
Sbjct: 12634 LESGDKYDIIADGKKRVLVVKDATLQDMGTYVV----MVGAARAAAHLT----------- 12678
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKW----RQLNQGGRI 1601
V KL + + +V E+ F +V N + K KW + +
Sbjct: 12679 ----VIEKLRIIVPLKDTKVKEQQEVVFNCEV------NTEGAKAKWFRNEEAIFDSSKY 12728
Query: 1602 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGE-IESNVNLQVNERKKQ--EKIEGDLR 1772
I QK L IRD D + N GE ++S NL V E + E ++ D+
Sbjct: 12729 IILQKDLVYTLRIRDARLDDQANFNVSLTNHRGENVKSAANLIVEEEDLRIVEPLK-DIE 12787
Query: 1773 AMLKKT 1790
M KK+
Sbjct: 12788 TMEKKS 12793
Score = 126 bits (317), Expect = 5e-29
Identities = 127/456 (27%), Positives = 201/456 (44%), Gaps = 4/456 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKL-RPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
G A + ++ G P+ WYK K+ R Y +NV LV V + DS +
Sbjct: 2098 GSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMV 2157
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRD-VQETVGLPVVFECAVSGSEP-ISVSWF 371
+A N GE SS FL VQ ++L +F+++L+D V + FEC SEP I V W+
Sbjct: 2158 KAINIAGETSSHAFLLVQAKQL-ITFTQELQDVVAKEKDTMATFECET--SEPFIKVKWY 2214
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDG + G + V L++ D S A YSC + ++A+LI+ EG
Sbjct: 2215 KDGIEVHAGDKYRMHSDRKVHFLSVLTIDTSDAEDYSCVLVED-ENIKTTAKLIV-EGAV 2272
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
F L ++ S + EC + + I+ W ++ E++S G Y I+ +LT
Sbjct: 2273 VEFVK-ELQDIEVPESYSGELEC-IISPENIEGKWYHNDVELKSNGKYSITSRRGRQNLT 2330
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
+ V K D G+Y+ + V+ GK + T +L +K R P + + LS+ + EG+ +LE
Sbjct: 2331 VKDVTKEDQGEYS-FVVD--GKKT-TCKLKMKPR--PIAILQGLSDQ-KVCEGDIVQLEV 2383
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
+V+ + + W K+ E+ + I + +L ++ + DAG Y+ + S
Sbjct: 2384 KVS-LENVEGVWMKDGQEVQHSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLST 2442
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
S+ + P L V V EG L C V + ++W +IKP DR
Sbjct: 2443 SGNVSVYSVDVITP------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR 2496
Query: 1272 CSFSFANGTAV-LEFKDVTKADAGDYVCKASNVAGS 1376
S GT L +D G Y V S
Sbjct: 2497 VQ-SIVKGTKQRLVINRTHASDEGPYKLMVGRVETS 2531
Score = 124 bits (311), Expect = 3e-28
Identities = 151/645 (23%), Positives = 250/645 (38%), Gaps = 36/645 (5%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV + GDS L C + G+ I + W K +++P+ F + A L + DS
Sbjct: 8348 PVTASEGDSVQLSCHVQGSEPIRIQWLKAGREVKPSDRCSFSFASGTAMLELKETAKADS 8407
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQ------LRDVQETVGLPVVFECAVS- 341
G+Y+C+A N G +S +T++E+ +++ L V E + VV + +
Sbjct: 8408 GDYVCKASNVAGSDTSKCKVTIKEKPAAAPAAKKAAVDGKLFFVSEPQSIRVVEKTTATF 8467
Query: 342 ----GSEPI-SVSWFKDG-RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPI 503
G +PI +V W K R L G I + A L I T ++ +G Y C A N
Sbjct: 8468 IAKVGGDPIPNVKWTKGKWRQLNQGGRILIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKH 8527
Query: 504 GSASSSARLILTEGRNPPFFD---------IPLAPVDAVVGESADFECHVTGTQP----- 641
G S+ L + E + + P + E D + P
Sbjct: 8528 GEIESNVNLQVDERKKQEKIEGDLRAMLKKTPALKKGSGEEEEIDIMELLKNVDPKEYEK 8587
Query: 642 -IKVAWAKDNREIRSGGNYQISYLENSAH-LTILKVDKGDTGQYTCYAVNEVGKDSCTAQ 815
++ D R + E H L I +++K + + K+
Sbjct: 8588 YARMYGITDFRGLLQAFELLKQSQEEETHRLEIEELEKSERDE----------KEFEELV 8637
Query: 816 LNIKERLI---PPSFTKKL-SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTAN 983
I++RL P + K + ++TV + F ++ ++ + I ++WYK ++ P+
Sbjct: 8638 AFIQQRLTQTEPVTLIKDIENQTVLKDNDAIFEIDIKINYPE-IKLSWYKGTEKLEPSNK 8696
Query: 984 CEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPV 1163
EI+ + L+VK D G Y SA T VI+ P +++HL V
Sbjct: 8697 YEISIDGDRHTLRVKNCQPKDQGNYRLVCGPHIASAKLT---VIE-----PAWERHLQDV 8748
Query: 1164 TVSEGEFLQLSCHVRGSEP-IRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAG 1340
T+ EG+ ++C S P ++ +W + GR +KP R + L DV D G
Sbjct: 8749 TLKEGQTCTMTCQF--SVPNVKSEWFRNGRVLKPQGRVKTEVEHKVHKLTIADVRAEDQG 8806
Query: 1341 DYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFI 1520
Y CK ++ S + + + F Q+I V E +ATF
Sbjct: 8807 QYTCKHEDLETSAELRIEAE------------------PIQFTKRIQNIVVSEHQSATFE 8848
Query: 1521 AKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVA-FNKH 1697
+V D V W KG +L + + G + I + T D G+Y +A
Sbjct: 8849 CEVSFDD-AIVTWYKGP-TELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPR 8906
Query: 1698 GEIESNVNLQVNERK-KQEKIEGDLRAMLKKTPVLKKGAGEEEEI 1829
GE S L + ++ K E D+ P + A EEI
Sbjct: 8907 GEARSTAELYLTTKEIKLEMKPPDIPDSRVPIPTMPIRAVPPEEI 8951
Score = 123 bits (309), Expect = 5e-28
Identities = 133/515 (25%), Positives = 212/515 (41%), Gaps = 6/515 (1%)
Frame = +3
Query: 216 GEVSSSTFLTVQEQKLP----PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGR 383
G+++ TF + + P P +++ G F V G W+K+G
Sbjct: 2063 GKITIPTFKPERIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGV 2122
Query: 384 PLKDGPNIQTSFL-DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
++ I + DNV L I + A N G SS A +L + +
Sbjct: 2123 KIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHA-FLLVQAKQLIT 2181
Query: 561 FDIPLAPVDAVVGES-ADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F L V A ++ A FEC T IKV W KD E+ +G Y++ L++L
Sbjct: 2182 FTQELQDVVAKEKDTMATFECE-TSEPFIKVKWYKDGIEVHAGDKYRMHSDRKVHFLSVL 2240
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+D D Y+C V + + TA+L ++ ++ F K+L + +E E S LE +
Sbjct: 2241 TIDTSDAEDYSCVLVEDENIKT-TAKLIVEGAVV--EFVKELQD-IEVPESYSGELE-CI 2295
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
+ I WY N+VE+ IT + L VK + D G Y+ V D C
Sbjct: 2296 ISPENIEGKWYHNDVELKSNGKYSITSRRGRQNLTVKDVTKEDQGEYSFVV--DGKKTTC 2353
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+K +P Q L+ V EG+ +QL V E + W+K G+E++ SDR
Sbjct: 2354 K----LKMKPRPIAILQGLSDQKVCEGDIVQLEVKV-SLENVEGVWMKDGQEVQHSDRVH 2408
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
+ +L +D+TK DAG+Y + S + V VD
Sbjct: 2409 IVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGNVSV--------------YSVD-- 2452
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
++ + + V+E T A KV + +VKW Q+ R+ KG + +L
Sbjct: 2453 --VITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLND-EQIKPDDRVQSIVKGTKQRLV 2509
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
I T +D G Y+ + G +E++ NL V + K
Sbjct: 2510 INRTHASDEGPYKLMV----GRVETSCNLSVEKIK 2540
Score = 120 bits (300), Expect = 5e-27
Identities = 135/564 (23%), Positives = 227/564 (40%), Gaps = 2/564 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G A L+C+++ V WY D +++P + + LV N+ ++D G
Sbjct: 2460 VNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQSIVKGTKQRLVINRTHASDEG 2519
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y + VG V +S L+V++ K+ R LRD+ T VVFE +S S I V
Sbjct: 2520 PY----KLMVGRVETSCNLSVEKIKI----IRGLRDLTCTETQNVVFEVELSHS-GIDVV 2570
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W G+ +K + + L + + G+Y+ A G ++S +L + G
Sbjct: 2571 WNFKGKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGEYAFYA----GENTTSGKLTVAGG 2626
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PL + A FEC V + + W KD + + N++ +
Sbjct: 2627 A----ISTPLTDQTVAESQEAVFECEVANPES-EGEWLKDGKHLALSNNFRGESDGHKRR 2681
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L I D G+YT +V +A+L ++ I + + TV ET+ F +
Sbjct: 2682 LVIAAAKLDDAGEYT----YKVATSKTSAKLKVEAVKIKKTLR---NLTVTETQDAVFSV 2734
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E + V W KN V + EI+ K L++K +M D +Y K+
Sbjct: 2735 E--LTHPDVKGVQWIKNGVVLDSNDKYEISVKGTLYSLKIKNCAMADESVYGFKLGRLGA 2792
Query: 1086 SA-LCTSSI-VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
SA L ++ +IK+PK VT E + V + + ++W EIK
Sbjct: 2793 SARLHVETVKIIKKPK----------DVTALENATVTFEVSV-SHDTVPVKWFHKNVEIK 2841
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
PSD+ L + ++ +DAG+Y + G K+K+
Sbjct: 2842 PSDKHRLVSERKVHKLMLQSISPSDAGEYTA----MVGQLECKAKLFVE----------- 2886
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
L +SI V E A+F +V +P++ G ++++ +I + +G
Sbjct: 2887 -----TLHITKTMKSIEVPETKAASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVV--QG 2939
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFN 1691
+L I +T+ DS Y V N
Sbjct: 2940 KLHQLIIMNTSTEDSAEYTFVCGN 2963
Score = 112 bits (280), Expect = 1e-24
Identities = 146/645 (22%), Positives = 251/645 (38%), Gaps = 62/645 (9%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G+S +L+C ++G P V+WY+ D ++ + +++ F+ +A L+ + + DSG
Sbjct: 955 VTVIEGESVTLECHISGYPSPKVTWYREDYQIESSIDFQITFQGGIARLMIREAFAEDSG 1014
Query: 186 EYICRAENSVGEVSSSTFLTVQ-------EQKLPPSFSR------QLRDVQET------- 305
+ C A N G VS+S +L VQ E L F+ + RDV T
Sbjct: 1015 RFTCSAVNEAGTVSTSCYLAVQVSEEFDKETTLTEKFATEEKRFVESRDVVMTDTSITEE 1074
Query: 306 ----------------------VGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSF 419
G VVFEC + G+ V W K G PL G + S+
Sbjct: 1075 QAGPGEPAAPFFISKPVVQKLVEGGSVVFECQIGGNPKPHVYWKKSGVPLTTGYRYKVSY 1134
Query: 420 LDNV--ATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI-------LTEGRNPPFFDIP 572
L I T AG+Y+ N G S+SA L+ L + + +
Sbjct: 1135 NKQTGECRLVISMTFADDAGEYTIVIRNKHGETSASASLLEEADYEALVKTQQEMLYQTQ 1194
Query: 573 LAPV--DAVVGESA------DFECHVTGTQP-IKVAWAKDNREIRSGGNYQISYLENSAH 725
++ + VGE A ++E Q I+ AKD +R+ Q ++ +
Sbjct: 1195 MSTFIQEPKVGEIAPGFAYSEYEKEYEKEQALIRKKMAKDTVMVRTFVEDQEFHISSFEE 1254
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
I +++ + E G++ ++ E I F ++ + EG
Sbjct: 1255 RLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESE-AIESGFDIRI-KNYRILEGMGVTF 1312
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITF-KNNALLLQVKKASMGDAGLYTCKVSNDA 1082
+++G +AWYK+ I ++ F ++ L++ D G+YT SN
Sbjct: 1313 HCKMSGYPLPKIAWYKDGKRIRHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIK 1372
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
G+A+C+ + + EP P ++ TP VS +S PIR+ + +
Sbjct: 1373 GNAICSGKLYV-EPAAPFSAPTYMPTPEAVS--RIRSVSPRSLSRSPIRMSPAMSPARMS 1429
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
P+ R S + + + + + +T +S++
Sbjct: 1430 PA-RMSPARMSPARMSPGRRL-----------------EETDESQLERLY---------- 1461
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
K FV +P S + +E TA F KV G P+P W + +N + ++
Sbjct: 1462 -----KPVFVLKPASFKCLEGQTARFDLKVVGRPMPETFWFHNGQQIVNDYTHKVVIKED 1516
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEK 1754
L I + +DSG + VA N+ G+ +V L V + Q K
Sbjct: 1517 GTQSLIIVPASPSDSGEWTVVAQNRAGKSTISVTLTVEAVEHQIK 1561
Score = 112 bits (279), Expect = 1e-24
Identities = 148/673 (21%), Positives = 245/673 (36%), Gaps = 48/673 (7%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVD--SNDS 182
+V G + + P V WY +L+ ++ K+H+ N L +D + D
Sbjct: 32427 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTLEILDCQTEDG 32484
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y N GE S L V +++ Q RD + +P ++ +E +V
Sbjct: 32485 GTYRAVCTNYKGEASDYATLDVTGGAYT-TYASQRRDEE----VPKSVFPELTKTEAYAV 32539
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL---- 530
S FK L+ +++ T T +A +AT+ S A +
Sbjct: 32540 SSFKRTSELEAASSVREVKSQMTETRESLSTYEHYASAEMKSATSEEKSLEEKATVRKIK 32599
Query: 531 ------ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
ILT+ R+ + GESA F C G V W ++ + + +
Sbjct: 32600 TTLAARILTKPRS----------ITVHEGESARFSCDTDGEPVPTVTWLREGQVVSTSAR 32649
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI-KERLIPPSFT----- 854
+Q++ + + I V D G Y+ N GK L + K R+I + T
Sbjct: 32650 HQVTTTKYKSTFEISSVQASDEGNYSVVVENSDGKQEAQFTLTVQKARVIEKAVTSPPRV 32709
Query: 855 KKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKA 1034
K V+ E + + RV +P++ HP A K
Sbjct: 32710 KSPEPRVKSPE--TVKSPKRVKSPEPVT---------SHPKAVSPTETK----------- 32747
Query: 1035 SMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGS 1214
+ G L S+ PP Q L + + +L+C V S
Sbjct: 32748 ------------PTEKGQHLPVSA--------PPKITQSLK--AEASKDIAKLTCAVESS 32785
Query: 1215 E--PIRIQWLKAGREIKPSDRCSFSF-ANGTAVLEFKDVTKADAGDYVCKASNVAG---- 1373
+ W K G+++K + F + A+GT L+ +++++D G+YVC+ S G
Sbjct: 32786 ALCAKEVAWYKDGKKLKENGHFQFHYSADGTYELKIHNLSESDCGEYVCEVSGEGGTSKT 32845
Query: 1374 -------------------SDTSKS--KVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIR 1490
S+T+KS K + K V+ +
Sbjct: 32846 SFQFTGQSFKSIHEQVSSISETTKSVQKTAESAEAKKSEPIAPESISSKPVIVTGLRDTT 32905
Query: 1491 VVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGL 1670
V + A F KV G+P P + WTK + + QG + + +E LEI T +D GL
Sbjct: 32906 VSSDSVAKFTIKVTGEPQPTITWTK-DGKAIAQGSKYKLSSNKEEFILEILKTETSDGGL 32964
Query: 1671 YRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAGEE--EEIDIMEL 1844
Y C N G + S+ L + K E + + + T K A EE ++ E
Sbjct: 32965 YACTVTNSAGSVSSSCKLTIKAVKDTEAQKVSTQKTSEVTSQKKASAQEEISQKALTSEE 33024
Query: 1845 LKNVDPKEYEKYA 1883
+K + K +E A
Sbjct: 33025 IKMSEVKSHETLA 33037
Score = 111 bits (278), Expect = 2e-24
Identities = 73/220 (33%), Positives = 112/220 (50%), Gaps = 3/220 (1%)
Frame = +3
Query: 267 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDG--PNIQTSFLDNVATL 440
P F++ L+ V G FE VSGS VSWF+DG+ + P +Q SF D A L
Sbjct: 6 PMFTQPLQSVVVLEGSTATFEAHVSGSPVPEVSWFRDGQVISTSTLPGVQISFSDGRARL 65
Query: 441 NIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFEC 620
I ++ +G+YS ATN G A+S+A L++T PP F L + G +
Sbjct: 66 MIPAVTKANSGRYSLRATNGSGQATSTAELLVTAETAPPNFSQRLQSMTVRQGSQVRLQV 125
Query: 621 HVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKD 800
VTG V + +D EI+S ++QIS + L I + D+G Y+ A N VG+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRA 185
Query: 801 SCTAQLNIK-ERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+ TA+L ++ E ++P TK + T + +E R+E ++
Sbjct: 186 TSTAELVVQGEEVVPAKKTKTIVSTAQISETRQTRIEKKI 225
Score = 109 bits (272), Expect = 9e-24
Identities = 154/603 (25%), Positives = 240/603 (39%), Gaps = 6/603 (0%)
Frame = +3
Query: 15 TVGDS--ASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
TV +S A +C++A PE W K L + ++ + LV +D+GE
Sbjct: 2636 TVAESQEAVFECEVAN-PESEGEWLKDGKHLALSNNFRGESDGHKRRLVIAAAKLDDAGE 2694
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y + S +S L V+ K+ + LR++ T VF ++ + V W
Sbjct: 2695 YTYKVATS----KTSAKLKVEAVKI----KKTLRNLTVTETQDAVFSVELTHPDVKGVQW 2746
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K+G L + S + +L I + Y +G +SARL + +
Sbjct: 2747 IKNGVVLDSNDKYEISVKGTLYSLKIKNCAMADESVYGFK----LGRLGASARLHVETVK 2802
Query: 549 NPPFFDIPLAPVDAVVGESAD--FECHVT-GTQPIKVAWAKDNREIRSGGNYQISYLENS 719
I P D E+A FE V+ T P+K W N EI+ +++
Sbjct: 2803 ------IIKKPKDVTALENATVTFEVSVSHDTVPVK--WFHKNVEIKPSDKHRLVSERKV 2854
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L + + D G+YT VG+ C A+L ++ I + S V ET+ SF
Sbjct: 2855 HKLMLQSISPSDAGEYTAM----VGQLECKAKLFVETLHITKTMK---SIEVPETKAASF 2907
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
E + W KN VEI + +I + L + S D+ YT ND
Sbjct: 2908 ECE---VSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGND 2964
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
SA T + P + L + E + + V E I +WLK G EIK
Sbjct: 2965 QVSATLTVT--------PIMITSMLKDINAEEKDTITFEVTVN-YEGISYKWLKNGVEIK 3015
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
+DRC T L ++V DA DY + VAG TS + +
Sbjct: 3016 STDRCQMRTKKLTHSLNIRNVHFGDAADY----TFVAGKATSTATL-------------- 3057
Query: 1440 XXVDGK-LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
V+ + + F + I+V+EK A F +V +P V+W K ++L RI I ++
Sbjct: 3058 -YVEARHIEFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMK-DGQELQIADRIKIQKE 3114
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPV 1796
+L I T +D+G Y VA G S NL V R + +R++ K+ V
Sbjct: 3115 KYVHRLLIPSTRMSDAGKYTVVA----GGNMSTANLFVEGRDVR------IRSIKKEVQV 3164
Query: 1797 LKK 1805
++K
Sbjct: 3165 IEK 3167
Score = 107 bits (267), Expect = 3e-23
Identities = 148/580 (25%), Positives = 226/580 (38%), Gaps = 6/580 (1%)
Frame = +3
Query: 15 TVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYI 194
+VG SA +C ++ + I +W K + +R + ++ L V +D+GEY
Sbjct: 11174 SVGSSAIFECLVSPSTAI-TTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYT 11232
Query: 195 CRAENSVGEVSSSTFLTVQEQKLPPSFSRQL-RDVQETVGLPVVFECAVSGSEPISVSWF 371
C E +S+ L V+E LP F + L +V G P+ C ++ V W
Sbjct: 11233 CVLRLGNKEKTSTAKLIVEE--LPVRFVKTLEEEVTVVKGQPLYLSCELNKER--DVVWR 11288
Query: 372 KDGRPLKDGP-NIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL---ILT 539
KDG+ + + P I + + L I D + AG Y+ T N SS I+
Sbjct: 11289 KDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEIIR 11348
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E P D + P V F C + P + W K EI N + L+
Sbjct: 11349 EWLVKPIRDQHVKPKGTAV-----FTCDIAKDTP-NIKWFKGYDEIPLEPNDKTEILKEG 11402
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE-TVEETEGNS 896
HL LKV YAV GK A+L + ER + K + + T+ E E S
Sbjct: 11403 NHL-FLKVKNAMPEDIDEYAVEIEGK-RYPAKLTLGEREV--ELLKPIEDVTIYEKESAS 11458
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
F E + I W + P+ CEI + L + K + AG +V
Sbjct: 11459 FDAE---ISEEDIPGEWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAG----EVLY 11511
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
A +A+ T+ + +KE + F L VTV E + C + + + W K I
Sbjct: 11512 QACNAITTAILTVKEIELD--FAVPLKDVTVPEKRQARFECVL--TREANVIWSKGPDII 11567
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
K SD+ +L D D G Y + V G TS
Sbjct: 11568 KASDKFDIIADGKKHILVINDSQFDDEGVY---TAEVEGKKTSAQLFVTGI--------- 11615
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
+L F+S + V E TATF+ ++ + + +V W K + L+ + + +
Sbjct: 11616 ------RLKFISPLEDQTVKEGQTATFVCELSHEKM-HVVWFKNDVK-LHTTRTVLMSSE 11667
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
G KLEIR+TT D + N + S NL+V E
Sbjct: 11668 GKTYKLEIRETTLDDISQIKAQVKN----LSSTANLKVLE 11703
Score = 106 bits (264), Expect = 8e-23
Identities = 137/575 (23%), Positives = 218/575 (37%), Gaps = 3/575 (0%)
Frame = +3
Query: 3 PVK-VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSND 179
P+K VTV + + + T E V W KG ++ + + + LV N +D
Sbjct: 11534 PLKDVTVPEKRQARFECVLTREANVIWSKGPDIIKASDKFDIIADGKKHILVINDSQFDD 11593
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
G Y E + S+ F+T K F L D G F C +S E +
Sbjct: 11594 EGVYTAEVEGK--KTSAQLFVTGIRLK----FISPLEDQTVKEGQTATFVCELS-HEKMH 11646
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V WFK+ L + S L I +T Q N SS+A L +
Sbjct: 11647 VVWFKNDVKLHTTRTVLMSSEGKTYKLEIRETTLDDISQIKAQVKN----LSSTANLKVL 11702
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E P+F + L V + +C V+ P+K W KD EI + +
Sbjct: 11703 EA--DPYFTVKLHDKTGVEKDEIILKCEVSKDVPVK--WFKDGEEIVPSPKHSVKTDGLR 11758
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I K + D G+Y C + G D+ A + ++ RLI +K VE G +
Sbjct: 11759 RILKIKKAELKDKGEYVC----DCGTDTTKANVTVEARLIK---VEKPLYGVEVFVGETA 11811
Query: 900 RLEGRVAGSQP-ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
R E + S+P + W + + +CEI +L + + G ++S
Sbjct: 11812 RFE--IELSEPDVHGQWKLKGEPLTASPDCEIIEDGKKHVLVLYNCQLDMTG----EISF 11865
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
A +A +++ +KE P +F L+ V V E + + C V EP +WLK +EI
Sbjct: 11866 QAANAKSAANLKVKE--LPLIFITPLSDVKVFEKDEAKFECEV-SREPKTFRWLKGTQEI 11922
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
DR L K D Y+ +A + S
Sbjct: 11923 TGDDRFELIKDGTRHSLVIKSAAFEDEAKYMFEAEDKRTS-------------------G 11963
Query: 1437 XXXVDG-KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
++G +L F++ + + E+ A F ++ D IP V W K R L+ R+ +H
Sbjct: 11964 KLIIEGIRLKFLTPLKDVTAKERENAVFTVELSHDNIP-VSWFKNDQR-LHTSKRVSMHD 12021
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNV 1718
+G + +D + D+ R A E + V
Sbjct: 12022 EGKTHSITFKDLSIDDTSQIRVEAMGISSEAKLTV 12056
Score = 104 bits (260), Expect = 2e-22
Identities = 132/592 (22%), Positives = 222/592 (37%), Gaps = 4/592 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++V+ GD+ L C+++ P V WYKGD ++ T +++ L+ D+G
Sbjct: 12515 LEVSEGDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRFEILTDGRKRILIIQNAQLEDAG 12573
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y CR SS T V+ +L F + ++++ G F C +S E V
Sbjct: 12574 SYNCRLP------SSRTDSKVKVHELAAEFISKPQNLEILEGEKAEFVCTIS-KESFEVQ 12626
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W +D + L+ G L + G Y +G+A ++A L + E
Sbjct: 12627 WKRDDQTLESGDKYDIIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTVIEK 12682
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
+PL + F C V T+ K W ++ I Y I +
Sbjct: 12683 LR---IIVPLKDTKVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDLVYT 12738
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKD-SCTAQLNIKE---RLIPPSFTKKLSETVEETEGN 893
L I D + N G++ A L ++E R++ P K ET+E+
Sbjct: 12739 LRIRDARLDDQANFNVSLTNHRGENVKSAANLIVEEEDLRIVEPL---KDIETMEKKSVT 12795
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
+ R+ +++ W KN E+ L +K D G Y
Sbjct: 12796 FWCKVNRLN----VTLKWTKNGEEVAFDNRISYRIDKYKHSLIIKDCGFPDEGEYVVTAG 12851
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
D A ++I+ P + F +HL TV+E + SC + E ++W + GRE
Sbjct: 12852 QDKSVA---ELLIIEAPTE---FVEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGRE 12904
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
IK + F L KD D +Y C G + KS+
Sbjct: 12905 IKEGKKYKFEKDGSIHRLIIKDCRLEDECEYAC------GVEDRKSRARLFVE------- 12951
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
+ + + PQ I F+A++ D + V+W + + QG + +
Sbjct: 12952 -----EIPVEIIRPPQDILEAPGADVIFLAELNKDKV-EVQWLRNNMIVV-QGDKHQMMS 13004
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDL 1769
+G +L+I D D G YR +A +K E+ L++ K + + DL
Sbjct: 13005 EGKIHRLQICDIKPRDQGEYRFIAKDK----EARAKLELAAAPKIKTADQDL 13052
Score = 100 bits (250), Expect = 3e-21
Identities = 108/507 (21%), Positives = 186/507 (36%), Gaps = 40/507 (7%)
Frame = +3
Query: 330 CAVSGSEPIS--VSWFKDGRPLKDGPNIQTSF-LDNVATLNIFQTDRSFAGQYSCTATNP 500
CAV S + V+W+KDG+ LK+ + Q + D L I S G+Y C +
Sbjct: 32780 CAVESSALCAKEVAWYKDGKKLKENGHFQFHYSADGTYELKIHNLSESDCGEYVCEVSGE 32839
Query: 501 IGSASSSARLI----------------------LTEGRNPPFFDIPLAPV---------- 584
G++ +S + T P+AP
Sbjct: 32840 GGTSKTSFQFTGQSFKSIHEQVSSISETTKSVQKTAESAEAKKSEPIAPESISSKPVIVT 32899
Query: 585 ---DAVVGES--ADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDK 749
D V A F VTG + W KD + I G Y++S + L ILK +
Sbjct: 32900 GLRDTTVSSDSVAKFTIKVTGEPQPTITWTKDGKAIAQGSKYKLSSNKEEFILEILKTET 32959
Query: 750 GDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQ 929
D G Y C N G S + +L IK + +T E T + ++
Sbjct: 32960 SDGGLYACTVTNSAGSVSSSCKLTIKAVKDTEAQKVSTQKTSEVTSQKKASAQEEISQKA 33019
Query: 930 PISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSI 1109
S + V+ H T + + +VK+++ A L V + + +S
Sbjct: 33020 LTSEEIKMSEVKSHETLAIKEEASKVLIAEEVKRSAA--ASLEKSIVHEE----VTKTSQ 33073
Query: 1110 VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFA 1289
+E K T + +++G+ L ++ G+ ++ W+ G E+ S+ + +
Sbjct: 33074 ASEEVKTHAEIKTLSTQMNITKGQRATLKANIAGATDVK--WVLNGTELPNSEEYRYGVS 33131
Query: 1290 NGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFV 1469
L K + + G C G + +T + F+
Sbjct: 33132 GSDQTLTIKQASHREEGILSCIGKTSQGVVKCQFDLT-----------LSEELSDAPSFI 33180
Query: 1470 SEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDT 1649
++P+S + E F +V G+P P ++W K ++ I + + + LEIR+
Sbjct: 33181 TQPRSQNINEGQNVLFSCEVSGEPSPEIEWFKNN-LPISISSNISVSRSRNVYTLEIRNA 33239
Query: 1650 TKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+DSG Y A N HG+ + +L V
Sbjct: 33240 AVSDSGKYTIKAKNFHGQCSATASLTV 33266
Score = 94.0 bits (232), Expect = 4e-19
Identities = 124/575 (21%), Positives = 210/575 (36%), Gaps = 45/575 (7%)
Frame = +3
Query: 249 QEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFL-D 425
+ + + F ++++ + G+ V F C +SG ++W+KDG+ ++ G Q FL D
Sbjct: 1287 ESEAIESGFDIRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIRHGERYQMDFLQD 1346
Query: 426 NVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGES 605
A+L I G Y+ A+N G+A S +L + PF P V
Sbjct: 1347 GRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAA--PFSAPTYMPTPEAVSRI 1404
Query: 606 ADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVN 785
PI+++ A + S + + + ++++ D Q
Sbjct: 1405 RSVSPRSLSRSPIRMSPAMSPARM-SPARMSPARMSPARMSPGRRLEETDESQL------ 1457
Query: 786 EVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVE 965
ERL P F K + + + EG + R + +V G W+ N +
Sbjct: 1458 --------------ERLYKPVFVLKPA-SFKCLEGQTARFDLKVVGRPMPETFWFHNGQQ 1502
Query: 966 IHPTANCEITFKNNALL-LQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIK--EPKKPP 1136
I ++ K + L + AS D+G +T N AG + + ++ ++ E + P
Sbjct: 1503 IVNDYTHKVVIKEDGTQSLIIVPASPSDSGEWTVVAQNRAGKSTISVTLTVEAVEHQIKP 1562
Query: 1137 VFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS--DRCSFSFANGTAVLE 1310
F + L V + EG L++ G+ I WLK I P R G A L+
Sbjct: 1563 AFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPRIRIEGTRGEAALK 1622
Query: 1311 FKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV-------------- 1448
+ D+ Y A N AG DT++ KV +
Sbjct: 1623 IDSIISQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPE 1682
Query: 1449 --------------DGKLFFVSEPQSIRVVEKTTATFIAKVG-----------GDPIPNV 1553
+G L+ + Q +K T+ + + G GDP V
Sbjct: 1683 LEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVV 1742
Query: 1554 KWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
+W + L R+ + + L+ DSG+ C A NK+G ++ L V
Sbjct: 1743 EWLH-DGKPLEAANRLRMINEFGYCSLDYGAAYSRDSGVITCRATNKYGTDHTSATLIVK 1801
Query: 1734 ERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEIDIM 1838
+ K + E L P KKG EE++ M
Sbjct: 1802 DEKSLVE-ESQL-------PDGKKGLQRIEELERM 1828
Score = 94.0 bits (232), Expect = 4e-19
Identities = 83/323 (25%), Positives = 126/323 (39%), Gaps = 35/323 (10%)
Frame = +3
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS 1106
Q V WY ++ + EIT+++ + VK + D G Y CKV ND G +
Sbjct: 31639 QSTQVTWYFGVRQLENSEKYEITYEDGVATMYVKDITKFDDGTYRCKVVNDYGEDSSYAE 31698
Query: 1107 IVIKEPK------------------------KPPVFDQHLTPVTVSEGEFLQLSCHVRGS 1214
+ +K + +PP F L T GE ++ +
Sbjct: 31699 LFVKGVREVYDYYCRRTKKVKRRTDAMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVH 31758
Query: 1215 EPIRIQWLKAGREIKPSD---RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTS 1385
R+ W K+G++IKP D + +F G L VT D +Y A N G D+
Sbjct: 31759 PEPRVTWYKSGQKIKPGDDEKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKHGEDSC 31818
Query: 1386 KSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK 1565
K+K+T + F + E + F +V G P P +KW K
Sbjct: 31819 KAKLTVTLHPPPTETTL------RPMFKRLLANAECHEGQSVCFEIRVSGIPAPTLKWEK 31872
Query: 1566 GKWRQLNQGGRI-FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV---- 1730
+ L+ G I +H+ D L IRDT D+G YR A N G +LQV
Sbjct: 31873 DG-QPLSLGPHIEIVHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLR 31931
Query: 1731 ---NERKKQEKIEGDLRAMLKKT 1790
E + +E+ E ++ + KT
Sbjct: 31932 YVKQEFQSKEERERHVQKQIDKT 31954
Score = 92.8 bits (229), Expect = 9e-19
Identities = 95/385 (24%), Positives = 149/385 (38%), Gaps = 14/385 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ +T G A+L+ +AG + V W T+L + Y+ + TL Q + G
Sbjct: 33091 MNITKGQRATLKANIAGATD--VKWVLNGTELPNSEEYRYGVSGSDQTLTIKQASHREEG 33148
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLP-PSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
C + S G V LT+ E+ PSF Q R G V+F C VSG +
Sbjct: 33149 ILSCIGKTSQGVVKCQFDLTLSEELSDAPSFITQPRSQNINEGQNVLFSCEVSGEPSPEI 33208
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WFK+ P+ NI S NV TL I S +G+Y+ A N G S++A L +
Sbjct: 33209 EWFKNNLPISISSNISVSRSRNVYTLEIRNAAVSDSGKYTIKAKNFHGQCSATASLTVL- 33267
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECH-VTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
P + P P + V+ S+D H +Q ++++ +K S + S +
Sbjct: 33268 ----PLVEEP--PREVVLKTSSDVSLHGSVSSQSVQMSASKQEASFSSFSSSSASSMTEM 33321
Query: 720 --AHLTILKVDKGDTGQYTCYAVNEVGKDSCT-------AQLNIKERLIPPSFTKKLSET 872
A ++ + + + +GK S T L R IPP + L
Sbjct: 33322 KFASMSAQSMSSMQESFVEMSSSSFMGKSSMTQLESSTSRMLKAGGRGIPPKI-EALPSD 33380
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEI---HPTANCEITFKNNALLLQVKKASMG 1043
+ EG + G + W +I I ++ L +
Sbjct: 33381 ISIDEGKVLTVACAFTGEPTPEITWSCGGRKIQNQEQQGRFHIENTDDLTTLIIMDVQKQ 33440
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIK 1118
D GLYT + N+ GS T +I I+
Sbjct: 33441 DGGLYTLSLGNEFGSDSATVNINIR 33465
Score = 91.3 bits (225), Expect = 3e-18
Identities = 115/484 (23%), Positives = 186/484 (38%), Gaps = 7/484 (1%)
Frame = +3
Query: 243 TVQEQKLPPSFSRQLRDV----QETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQ 410
T Q + +P F ++++D+ E+VG +FEC VS S I+ +W KDG +++ P +
Sbjct: 11150 TYQLKAVPLKFVKEIKDIVLTEAESVGSSAIFECLVSPSTAIT-TWMKDGSNIRESPKHR 11208
Query: 411 TSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDA 590
L+I S AG+Y+C +S+A+LI+ E F V
Sbjct: 11209 FIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEE-LPVRFVKTLEEEVTV 11267
Query: 591 VVGESADFECHVTGTQPIKVAWAKDNR-EIRSGGNYQISYLENSAHLTILKVDKGDTGQY 767
V G+ C + + V W KD + + G + LTI D D G Y
Sbjct: 11268 VKGQPLYLSCELNKER--DVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTY 11325
Query: 768 TCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAW 947
T V C++ + + E +I K + + + +G + +A P ++ W
Sbjct: 11326 T-VTVENANNLECSSCVKVVE-IIREWLVKPIRDQHVKPKGTAV-FTCDIAKDTP-NIKW 11381
Query: 948 YK--NNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKE 1121
+K + + + P EI + N L L+VK A D Y ++ A T E
Sbjct: 11382 FKGYDEIPLEPNDKTEILKEGNHLFLKVKNAMPEDIDEYAVEIEGKRYPAKLTLGEREVE 11441
Query: 1122 PKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTA 1301
KP + VT+ E E + E I +W G ++PS C G
Sbjct: 11442 LLKP------IEDVTIYEKESASFDAEI-SEEDIPGEWKLKGELLRPSPTCEIKAEGGKR 11494
Query: 1302 VLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQ 1481
L V AG+ + +A N + K + +L F +
Sbjct: 11495 FLTLHKVKLDQAGEVLYQACNAITTAILTVK------------------EIELDFAVPLK 11536
Query: 1482 SIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTD 1661
+ V EK A F + + NV W+KG + + I G + L I D+ D
Sbjct: 11537 DVTVPEKRQARFECVLTRE--ANVIWSKGP-DIIKASDKFDIIADGKKHILVINDSQFDD 11593
Query: 1662 SGLY 1673
G+Y
Sbjct: 11594 EGVY 11597
Score = 90.5 bits (223), Expect = 4e-18
Identities = 123/575 (21%), Positives = 217/575 (37%), Gaps = 1/575 (0%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
KV GD L+ +++ GV W K +++ + + L+ + D+G
Sbjct: 2372 KVCEGDIVQLEVKVSLENVEGV-WMKDGQEVQHSDRVHIVIDKQSHMLLIEDMTKEDAGN 2430
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y ++G +S + P L+DV G V EC VS + SV W
Sbjct: 2431 YSFTIP-ALGLSTSGNVSVYSVDVITP-----LKDVNVIEGTKAVLECKVSVPDVTSVKW 2484
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+ + +K +Q+ L I +T S G Y +G +S L + + +
Sbjct: 2485 YLNDEQIKPDDRVQSIVKGTKQRLVINRTHASDEGPYKLM----VGRVETSCNLSVEKIK 2540
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
L + ++ FE ++ + I V W +EI+ Y+I L
Sbjct: 2541 ----IIRGLRDLTCTETQNVVFEVELSHS-GIDVVWNFKGKEIKPSSKYKIEAHGKIYKL 2595
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
T+L + K D G+Y YA G+++ + +L + I T +TV E++ F E
Sbjct: 2596 TVLNMMKDDEGEYAFYA----GENTTSGKLTVAGGAISTPLT---DQTVAESQEAVFECE 2648
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+ W K+ + + N + L + A + DAG YT KV+ S
Sbjct: 2649 ---VANPESEGEWLKDGKHLALSNNFRGESDGHKRRLVIAAAKLDDAGEYTYKVATSKTS 2705
Query: 1089 A-LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
A L ++ IK+ L +TV+E + S + + +QW+K G + +
Sbjct: 2706 AKLKVEAVKIKKT---------LRNLTVTETQDAVFSVELTHPDVKGVQWIKNGVVLDSN 2756
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
D+ S L+ K+ AD Y K + S +
Sbjct: 2757 DKYEISVKGTLYSLKIKNCAMADESVYGFKLGRLGASARLHVETVK-------------- 2802
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
+ +P+ + +E T TF V D +P VKW K ++ + + +
Sbjct: 2803 ------IIKKPKDVTALENATVTFEVSVSHDTVP-VKWFH-KNVEIKPSDKHRLVSERKV 2854
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
KL ++ + +D+G Y + G++E L V
Sbjct: 2855 HKLMLQSISPSDAGEYTAMV----GQLECKAKLFV 2885
Score = 90.1 bits (222), Expect = 6e-18
Identities = 133/560 (23%), Positives = 222/560 (39%), Gaps = 3/560 (0%)
Frame = +3
Query: 24 DSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRA 203
+SAS +++ +I W LRP+ T ++ L ++V + +GE + +A
Sbjct: 11455 ESASFDAEIS-EEDIPGEWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQA 11513
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGR 383
N++ ++ LTV+E +L F+ L+DV FEC ++ +V W K
Sbjct: 11514 CNAI----TTAILTVKEIEL--DFAVPLKDVTVPEKRQARFECVLT--REANVIWSKGPD 11565
Query: 384 PLK--DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
+K D +I ++ +N Q D G Y T + +SA+L +T R
Sbjct: 11566 IIKASDKFDIIADGKKHILVINDSQFDDE--GVY----TAEVEGKKTSAQLFVTGIRLK- 11618
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F PL G++A F C ++ + + V W K++ ++ + +S + L I
Sbjct: 11619 -FISPLEDQTVKEGQTATFVCELSH-EKMHVVWFKNDVKLHTTRTVLMSSEGKTYKLEIR 11676
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+ D Q N S TA L + E P FT KL + E + L+ V
Sbjct: 11677 ETTLDDISQIKAQVKNL----SSTANLKVLEA--DPYFTVKLHDKTG-VEKDEIILKCEV 11729
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
S+ + V W+K+ EI P+ + +L++KKA + D G Y C D A
Sbjct: 11730 --SKDVPVKWFKDGEEIVPSPKHSVKTDGLRRILKIKKAELKDKGEYVCDCGTDTTKANV 11787
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEP-IRIQWLKAGREIKPSDRC 1274
T + + +KP L V V GE + + SEP + QW G + S C
Sbjct: 11788 TVEARLIKVEKP------LYGVEVFVGETARFEIEL--SEPDVHGQWKLKGEPLTASPDC 11839
Query: 1275 SFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDG 1454
VL + G+ +A+N + K K +
Sbjct: 11840 EIIEDGKKHVLVLYNCQLDMTGEISFQAANAKSAANLKVK------------------EL 11881
Query: 1455 KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKL 1634
L F++ ++V EK A F +V +P +W KG +++ R + + G L
Sbjct: 11882 PLIFITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGT-QEITGDDRFELIKDGTRHSL 11939
Query: 1635 EIRDTTKTDSGLYRCVAFNK 1694
I+ D Y A +K
Sbjct: 11940 VIKSAAFEDEAKYMFEAEDK 11959
Score = 87.4 bits (215), Expect = 4e-17
Identities = 84/309 (27%), Positives = 128/309 (41%), Gaps = 37/309 (11%)
Frame = +3
Query: 72 VSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQ 251
V+WY G +L + Y++ + + VAT+ + D G Y C+ N GE SS L V+
Sbjct: 31643 VTWYFGVRQLENSEKYEITYEDGVATMYVKDITKFDDGTYRCKVVNDYGEDSSYAELFVK 31702
Query: 252 EQK------------------------LPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
+ PP F+ L + VG V F ++
Sbjct: 31703 GVREVYDYYCRRTKKVKRRTDAMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPR 31762
Query: 360 VSWFKDGRPLKDGPNIQTSFLDN-----VATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
V+W+K G+ +K G + + ++ T+N TD +Y+ A N G S A
Sbjct: 31763 VTWYKSGQKIKPGDDEKKYTFESDKGLYQLTINSVTTDDD--AEYTVVARNKHGEDSCKA 31820
Query: 525 RLILTEGRNP------PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSG 686
+L +T P P F LA + G+S FE V+G + W KD + + G
Sbjct: 31821 KLTVTLHPPPTETTLRPMFKRLLANAECHEGQSVCFEIRVSGIPAPTLKWEKDGQPLSLG 31880
Query: 687 GNYQISY--LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKK 860
+ +I + L+ A L I DTG Y A N G SC A L + ERL + K+
Sbjct: 31881 PHIEIVHEGLDYYA-LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV-ERL---RYVKQ 31935
Query: 861 LSETVEETE 887
++ EE E
Sbjct: 31936 EFQSKEERE 31944
Score = 85.1 bits (209), Expect = 2e-16
Identities = 93/439 (21%), Positives = 165/439 (37%), Gaps = 61/439 (13%)
Frame = +3
Query: 264 PPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLN 443
PP+ L++V G V EC +SG V+W+++ ++ + Q +F +A L
Sbjct: 945 PPTLVSGLKNVTVIEGESVTLECHISGYPSPKVTWYREDYQIESSIDFQITFQGGIARLM 1004
Query: 444 IFQTDRSFAGQYSCTATNPIGSASSSARL------------------------------- 530
I + +G+++C+A N G+ S+S L
Sbjct: 1005 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFDKETTLTEKFATEEKRFVESRDV 1064
Query: 531 ------ILTEGRNP-----PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI 677
I E P PFF V G S FEC + G V W K +
Sbjct: 1065 VMTDTSITEEQAGPGEPAAPFFISKPVVQKLVEGGSVVFECQIGGNPKPHVYWKKSGVPL 1124
Query: 678 RSGGNYQISYLENS--AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF 851
+G Y++SY + + L I D G+YT N+ G+ S +A L E +
Sbjct: 1125 TTGYRYKVSYNKQTGECRLVISMTFADDAGEYTIVIRNKHGETSASASL--LEEADYEAL 1182
Query: 852 TKKLSETVEETEGNSFRLEGRVAGSQP-ISVAWYKNNVEIHPTANCEITFKNNALLLQVK 1028
K E + +T+ ++F E +V P + + Y+ E + K+ ++
Sbjct: 1183 VKTQQEMLYQTQMSTFIQEPKVGEIAPGFAYSEYEKEYEKEQALIRKKMAKDTVMVRTFV 1242
Query: 1029 KASMGDAGLYTCKVSNDAGSALCTSSI--VIKEPKKPPV-------------FDQHLTPV 1163
+ + ++ + + +++ +++E + + FD +
Sbjct: 1243 EDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAIESGFDIRIKNY 1302
Query: 1164 TVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSF-ANGTAVLEFKDVTKADAG 1340
+ EG + C + G +I W K G+ I+ +R F +G A L V D G
Sbjct: 1303 RILEGMGVTFHCKMSGYPLPKIAWYKDGKRIRHGERYQMDFLQDGRASLRIPVVLPEDEG 1362
Query: 1341 DYVCKASNVAGSDTSKSKV 1397
Y ASN+ G+ K+
Sbjct: 1363 IYTAFASNIKGNAICSGKL 1381
Score = 82.8 bits (203), Expect = 9e-16
Identities = 64/182 (35%), Positives = 81/182 (44%), Gaps = 11/182 (6%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRP---TATYKMHFRNNVATLVFNQVDSNDSGE 188
VG++ + PE V+WYK K++P Y + L N V ++D E
Sbjct: 31745 VGENVRFGVTITVHPEPRVTWYKSGQKIKPGDDEKKYTFESDKGLYQLTINSVTTDDDAE 31804
Query: 189 YICRAENSVGEVSSSTFLTVQ------EQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
Y A N GE S LTV E L P F R L + + G V FE VSG
Sbjct: 31805 YTVVARNKHGEDSCKAKLTVTLHPPPTETTLRPMFKRLLANAECHEGQSVCFEIRVSGIP 31864
Query: 351 PISVSWFKDGRPLKDGPNIQT--SFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
++ W KDG+PL GP+I+ LD A L+I T G Y TATN GS S A
Sbjct: 31865 APTLKWEKDGQPLSLGPHIEIVHEGLDYYA-LHIRDTLPEDTGYYRVTATNTAGSTSCQA 31923
Query: 525 RL 530
L
Sbjct: 31924 HL 31925
Score = 82.4 bits (202), Expect = 1e-15
Identities = 53/180 (29%), Positives = 96/180 (53%), Gaps = 3/180 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATY---KMHFRNNVATLVFNQVDSN 176
V V G +A+ + ++G+P VSW++ D ++ T+T ++ F + A L+ V
Sbjct: 15 VVVLEGSTATFEAHVSGSPVPEVSWFR-DGQVISTSTLPGVQISFSDGRARLMIPAVTKA 73
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
+SG Y RA N G+ +S+ L V + PP+FS++L+ + G V + V+G
Sbjct: 74 NSGRYSLRATNGSGQATSTAELLVTAETAPPNFSQRLQSMTVRQGSQVRLQVRVTGIPTP 133
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
V +++DG ++ + Q S ++ +L I + +G YS ATN +G A+S+A L++
Sbjct: 134 VVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELVV 193
Score = 80.1 bits (196), Expect = 6e-15
Identities = 98/457 (21%), Positives = 178/457 (38%)
Frame = +3
Query: 30 ASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAEN 209
A+ +C+ + P I V WYK ++ Y+MH V L +D++D+ +Y C
Sbjct: 2198 ATFECETS-EPFIKVKWYKDGIEVHAGDKYRMHSDRKVHFLSVLTIDTSDAEDYSCVL-- 2254
Query: 210 SVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPL 389
V + + T + + F ++L+D++ EC +S E I W+ + L
Sbjct: 2255 -VEDENIKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIIS-PENIEGKWYHNDVEL 2312
Query: 390 KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDI 569
K + L + + G+YS + ++ +L + P
Sbjct: 2313 KSNGKYSITSRRGRQNLTVKDVTKEDQGEYSFV----VDGKKTTCKLKMKP--RPIAILQ 2366
Query: 570 PLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDK 749
L+ G+ E V+ + ++ W KD +E++ I + S L I + K
Sbjct: 2367 GLSDQKVCEGDIVQLEVKVS-LENVEGVWMKDGQEVQHSDRVHIVIDKQSHMLLIEDMTK 2425
Query: 750 GDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQ 929
D G Y+ + + +G + +I P + V EG LE +V+
Sbjct: 2426 EDAGNYS-FTIPALGLSTSGNVSVYSVDVITP------LKDVNVIEGTKAVLECKVSVPD 2478
Query: 930 PISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSI 1109
SV WY N+ +I P + K L + + D G Y V G + ++
Sbjct: 2479 VTSVKWYLNDEQIKPDDRVQSIVKGTKQRLVINRTHASDEGPYKLMV----GRVETSCNL 2534
Query: 1110 VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFA 1289
+++ K + L +T +E + + + S I + W G+EIKPS +
Sbjct: 2535 SVEKIK----IIRGLRDLTCTETQNVVFEVELSHS-GIDVVWNFKGKEIKPSSKYKIEAH 2589
Query: 1290 NGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
L ++ K D G+Y + AG +T+ K+T
Sbjct: 2590 GKIYKLTVLNMMKDDEGEY----AFYAGENTTSGKLT 2622
Score = 79.0 bits (193), Expect = 1e-14
Identities = 70/283 (24%), Positives = 115/283 (40%), Gaps = 31/283 (10%)
Frame = +3
Query: 1122 PKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTA 1301
P PP L VTV EGE + L CH+ G ++ W + +I+ S +F G A
Sbjct: 942 PVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPKVTWYREDYQIESSIDFQITFQGGIA 1001
Query: 1302 VLEFKDVTKADAGDYVCKASNVAGS-----------------DTSKSKVTXXXXXXXXXX 1430
L ++ D+G + C A N AG+ +T+ ++
Sbjct: 1002 RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFDKETTLTEKFATEEKRFVES 1061
Query: 1431 XXXXXVDGKL-------------FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-G 1568
D + FF+S+P ++VE + F ++GG+P P+V W K G
Sbjct: 1062 RDVVMTDTSITEEQAGPGEPAAPFFISKPVVQKLVEGGSVVFECQIGGNPKPHVYWKKSG 1121
Query: 1569 KWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQ 1748
++ +++ E +L I T D+G Y V NKHGE ++ +L E
Sbjct: 1122 VPLTTGYRYKVSYNKQTGECRLVISMTFADDAGEYTIVIRNKHGETSASASLL--EEADY 1179
Query: 1749 EKIEGDLRAMLKKTPVLKKGAGEEEEIDIMELLKNVDPKEYEK 1877
E + + ML +T + + +E + E+ EYEK
Sbjct: 1180 EALVKTQQEMLYQTQM----STFIQEPKVGEIAPGFAYSEYEK 1218
Score = 77.8 bits (190), Expect = 3e-14
Identities = 134/649 (20%), Positives = 226/649 (34%), Gaps = 94/649 (14%)
Frame = +3
Query: 30 ASLQCQLA--GTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRA 203
A +C+L G P + V W L +M +L + S DSG CRA
Sbjct: 1726 AHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGAAYSRDSGVITCRA 1785
Query: 204 ENSVGEVSSSTFLTVQEQKLP------PSFSRQLRDVQETV------------------- 308
N G +S L V+++K P + L+ ++E
Sbjct: 1786 TNKYGTDHTSATLIVKDEKSLVEESQLPDGKKGLQRIEELERMAHEGALTGVTTDQKEKQ 1845
Query: 309 ---------------GLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLN 443
G F C V+G V+W+ +G+ ++ + + D + L+
Sbjct: 1846 KPDIVLFPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY-DGIHYLD 1904
Query: 444 IFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN------------PPF--------- 560
I G+ TA NP G +L + + + P F
Sbjct: 1905 IVDCKSYDTGEVKVTAENPEGVTEHKVKLEIQQREDFRSVLRRAPEPKPEFHVHEPGKLQ 1964
Query: 561 FDIPLA--PVD------AVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE- 713
F++ PVD V + A+ H ++ + +K R G I+ +E
Sbjct: 1965 FEVQKVDRPVDTSETKEVVKLKRAERITHEKVSEESEELRSKFKRRTEEGYYEAITAVEL 2024
Query: 714 -----NSAHLTILKVDKGDTGQYT-------CYAVNEVGKDSCTAQLNIKERLIPPSFTK 857
+ ++ +LK K + +T A+ E GK + + L P
Sbjct: 2025 KSRKKDESYEELLKKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPERIELSPSMEAP 2084
Query: 858 KLSETVEET---EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITF-KNNALLLQV 1025
K+ E ++ +G+ RV G WYKN V+I + + ++N L +
Sbjct: 2085 KIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVI 2144
Query: 1026 KKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHV 1205
+ + D+ K N AG + + ++ + K+ F Q L V E + + +
Sbjct: 2145 RDVTAEDSASIMVKAINIAGET-SSHAFLLVQAKQLITFTQELQDVVAKEKDTM-ATFEC 2202
Query: 1206 RGSEP-IRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
SEP I+++W K G E+ D+ L + +DA DY C T
Sbjct: 2203 ETSEPFIKVKWYKDGIEVHAGDKYRMHSDRKVHFLSVLTIDTSDAEDYSCVLVEDENIKT 2262
Query: 1383 SKSKVTXXXXXXXXXXXXXXXVDGKLF-FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW 1559
+ + V+G + FV E Q I V E + + + I
Sbjct: 2263 TAKLI----------------VEGAVVEFVKELQDIEVPESYSGELECIISPENI----- 2301
Query: 1560 TKGKWR----QLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNK 1694
+GKW +L G+ I + L ++D TK D G Y V K
Sbjct: 2302 -EGKWYHNDVELKSNGKYSITSRRGRQNLTVKDVTKEDQGEYSFVVDGK 2349
Score = 77.0 bits (188), Expect = 5e-14
Identities = 125/532 (23%), Positives = 206/532 (38%), Gaps = 34/532 (6%)
Frame = +3
Query: 246 VQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLD 425
V E + P+FS VQ VG + E +SG S+SW KDG PLK I +
Sbjct: 23270 VIEPDVRPAFSSY--SVQ--VGQDLKIEVPISGRPKPSISWTKDGMPLKQTTRINVTDSL 23325
Query: 426 NVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGES 605
++ TL+I +T + GQY T +N +G +++ +I + +PP + + A
Sbjct: 23326 DLTTLSIKETHKDDGGQYGITVSNVVGQKTAAIEIITLDKPDPPKGPVKFDEISA----- 23380
Query: 606 ADFECHVTGTQPIKVAWAKDNREIRSGG----NYQISYLENSAHL----------TILKV 743
+ I ++W N + +GG NY + + + + T LKV
Sbjct: 23381 ----------ESITLSW---NPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKV 23427
Query: 744 DKGDTG---QYTCYAVNEVGK------DSCTAQLNIKERLIP--PSFT--KKLSETVEET 884
K TG Q+ +A N G+ + AQ KE P P T K S V+
Sbjct: 23428 TKLKTGTEYQFRIFAENRYGQSFALESEPVVAQYPYKEPGPPGTPFVTAISKESMVVQWH 23487
Query: 885 E----GNSFRLEGRVAGSQPISVAWYK-NNVEIHPTANCEITFKNNALLLQVKKASMGDA 1049
E G S + + + S+ W K N IH T FK L +++ +
Sbjct: 23488 EPINNGGSPVIGYHLERKERNSILWTKVNKTIIHDT-----QFK----ALNLEEGIEYEF 23538
Query: 1050 GLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEF-LQLSCHVRGSEPIR 1226
+Y + ++ + V ++P PP + + V E LQ + V +
Sbjct: 23539 RVYAENIVGVGKASKNSECYVARDPCDPPGTPE---AIIVKRNEITLQWTKPVYDGGSMI 23595
Query: 1227 IQWLKAGREIKPSDRCSFSFANGTAV-LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTX 1403
++ R++ SF N +T+ ++ A N AG+ + S T
Sbjct: 23596 TGYIVEKRDLPEGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTG 23655
Query: 1404 XXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQL 1583
+D K +I V T A V G P+P ++W +G +++
Sbjct: 23656 PITAKDEVELPRISMDPKF-----RDTIVVNAGETFRLEADVHGKPLPTIEWLRGD-KEI 23709
Query: 1584 NQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
+ R I +A L ++D + D G Y A N G VN++V +R
Sbjct: 23710 EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR 23761
Score = 76.6 bits (187), Expect = 7e-14
Identities = 94/410 (22%), Positives = 154/410 (37%), Gaps = 19/410 (4%)
Frame = +3
Query: 213 VGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLK 392
V E + T +E K + T G + ++G+ V W +G L
Sbjct: 33064 VHEEVTKTSQASEEVKTHAEIKTLSTQMNITKGQRATLKANIAGAT--DVKWVLNGTELP 33121
Query: 393 DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN--PPFFD 566
+ + + TL I Q G SC G L L+E + P F
Sbjct: 33122 NSEEYRYGVSGSDQTLTIKQASHREEGILSCIGKTSQGVVKCQFDLTLSEELSDAPSFIT 33181
Query: 567 IPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVD 746
P + + G++ F C V+G ++ W K+N I N +S N L I
Sbjct: 33182 QPRSQ-NINEGQNVLFSCEVSGEPSPEIEWFKNNLPISISSNISVSRSRNVYTLEIRNAA 33240
Query: 747 KGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGS 926
D+G+YT A N G+ S TA L + + P E V +T + L G V+ S
Sbjct: 33241 VSDSGKYTIKAKNFHGQCSATASLTVLPLVEEPP-----REVVLKTSSD-VSLHGSVS-S 33293
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK---VSNDAGSALC 1097
Q + ++ K ++ + + + ++K ASM + + + V + S +
Sbjct: 33294 QSVQMSASKQEASFSSFSS-----SSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMG 33348
Query: 1098 TSSIVIKEPKK-----------PPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKA 1244
SS+ E PP + + +++ EG+ L ++C G I W
Sbjct: 33349 KSSMTQLESSTSRMLKAGGRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEITWSCG 33408
Query: 1245 GREIKPSD---RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTS 1385
GR+I+ + R + L DV K D G Y N GSD++
Sbjct: 33409 GRKIQNQEQQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSA 33458
Score = 75.5 bits (184), Expect = 1e-13
Identities = 56/230 (24%), Positives = 102/230 (44%), Gaps = 2/230 (0%)
Frame = +3
Query: 843 PSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTA--NCEITFKNNALL 1016
P FT+ L ++V EG++ E V+GS V+W+++ I + +I+F +
Sbjct: 6 PMFTQPL-QSVVVLEGSTATFEAHVSGSPVPEVSWFRDGQVISTSTLPGVQISFSDGRAR 64
Query: 1017 LQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLS 1196
L + + ++G Y+ + +N +G A T+ +++ PP F Q L +TV +G ++L
Sbjct: 65 LMIPAVTKANSGRYSLRATNGSGQATSTAELLVTAETAPPNFSQRLQSMTVRQGSQVRLQ 124
Query: 1197 CHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGS 1376
V G +++ + G EI+ S S L + D+G Y A+N G
Sbjct: 125 VRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 1377 DTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAK 1526
TS +++ V +SE + R+ +K A F A+
Sbjct: 185 ATSTAELVVQGEEVVPAKKTKTIVSTAQ--ISETRQTRIEKKIEAHFDAR 232
Score = 75.1 bits (183), Expect = 2e-13
Identities = 127/559 (22%), Positives = 208/559 (37%), Gaps = 44/559 (7%)
Frame = +3
Query: 186 EYICRAENSVG-------EVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSG 344
E+ AEN G +S T LT E P +++ DV +G C + G
Sbjct: 30545 EFRVFAENETGLSRPRRTAMSVKTKLTSGEA---PGVRKEMADVTTKLGEAAQLSCQIVG 30601
Query: 345 SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
+ W++ G+ L + S TL + ++ G Y+C ATN +G SS+
Sbjct: 30602 RPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTDEQEDEGVYTCVATNEVGEVESSS 30661
Query: 525 RLILTEGRNPPFFDIPLAPVD----AVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
+L+L P F P P+ VG + G + W + +++
Sbjct: 30662 KLLLQAA--PQFH--PGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSEK 30717
Query: 693 YQISYLENSAHLTILKVD-KGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE 869
I E+ HL + V K G+Y N G T + I+++ P+ +
Sbjct: 30718 ITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNAFGTVDATLDVEIQDKPDKPTGPIVIEA 30777
Query: 870 TVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDA 1049
++ + S++ GS W N V CE K A V A
Sbjct: 30778 LLKNSVVISWKPPADDGGS------WITNYV----VEKCEA--KEGAEWQLVSSA----I 30821
Query: 1050 GLYTCKVSN---DAG-----SALCT----------SSIVIKEP-KKPPVFDQ-HLTPVT- 1166
+ TC++ N +AG SA T S ++IK P +KP V + +T VT
Sbjct: 30822 SVTTCRIVNLTENAGYYFRVSAQNTFGISEPLEVASIVIIKSPFEKPGVPGKPTITAVTK 30881
Query: 1167 ----------VSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFK 1316
S+G + ++ E + +W+ E FS N LE++
Sbjct: 30882 DSCVVAWKPPASDGGAKIRNYYLERREKKQNKWIAVTTE--EIRETVFSVQNLIEGLEYE 30939
Query: 1317 DVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVV 1496
K + + S ++ T KS V F E +++ V
Sbjct: 30940 FRVKCENLGGESEWSEISEPVTPKSDVPIQAP----------------HFKEELRNLNVR 30983
Query: 1497 EKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ-KGDEAKLEIRDTTKTDSGLY 1673
++ AT + KV G P P VKW + + G + I + KG +L I T D+ +Y
Sbjct: 30984 YQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVY 31043
Query: 1674 RCVAFNKHGEIESNVNLQV 1730
+ A N+ G + +L+V
Sbjct: 31044 QVRATNQGGSVSGTASLEV 31062
Score = 74.7 bits (182), Expect = 2e-13
Identities = 108/435 (24%), Positives = 163/435 (37%), Gaps = 23/435 (5%)
Frame = +3
Query: 165 VDSNDSGEYICRAENSVG---EVSSSTFLTVQEQKLPPSF---SRQLRDVQETVGLPVVF 326
+D N E+ A+N VG + +E PP + + V G P+
Sbjct: 18610 LDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVVVRAGCPIRL 18669
Query: 327 ECAVSGSEPISVSWFKDG--RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNP 500
V G V+W K G ++ G Q +D +A L I + R +G+YS T NP
Sbjct: 18670 FAIVRGRPAPKVTWRKVGIDNVVRKG---QVDLVDTMAFLVIPNSTRDDSGKYSLTLVNP 18726
Query: 501 IGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVT--------GTQPIKVAW 656
G + N D P D V + CHV+ G+Q
Sbjct: 18727 AGEKAVFV--------NVKVLDTPGPVADLKVSDVTKTSCHVSWAPPENDGGSQVTHYIV 18778
Query: 657 AKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCT---AQLNIK 827
K E ++ + S ++T L G+ + AVNE G T +
Sbjct: 18779 EKREAERKTWSTVTPEVKKTSFNVTNLV--PGNEYFFRVTAVNEYGPGVPTDIPKPVLAS 18836
Query: 828 ERLIPPSFTKKLSETVEETEGNSFR--LEGRVAGSQPISVAWYKNNVEIHPTANCEITFK 1001
+ L P +KL E E T+ ++ L G I E P
Sbjct: 18837 DPLSEPDPPRKL-EVTEMTKNSATLAWLPPLRDGGAKIDGYIISYREEDQPADRWTEYSV 18895
Query: 1002 NNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP--VTVSE 1175
L L V G + N G ++ + + E K+ + + L P +T+
Sbjct: 18896 VKDLSLIVTGLKEGKKYKFRVAARNAVGVSMPREAEGVYEAKEQLLPPKILMPEQITIKA 18955
Query: 1176 GEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCK 1355
G+ L++ HV G +W K E+ S + A+G++VL KDVT+ D+G Y
Sbjct: 18956 GKKLRVEAHVYGKPNPICKWKKGDDEVVTSSHLAIHKADGSSVLIIKDVTRKDSGYYSLT 19015
Query: 1356 ASNVAGSDTSKSKVT 1400
A N +GSDT K KVT
Sbjct: 19016 AENSSGSDTQKIKVT 19030
Score = 73.2 bits (178), Expect = 7e-13
Identities = 131/577 (22%), Positives = 220/577 (38%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+V VG++A + +L+ P++ W L + ++ LV + +G
Sbjct: 11803 VEVFVGETARFEIELS-EPDVHGQWKLKGEPLTASPDCEIIEDGKKHVLVLYNCQLDMTG 11861
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
E +A N+ S+ L V+E LP F L DV+ FEC VS EP +
Sbjct: 11862 EISFQAANA----KSAANLKVKE--LPLIFITPLSDVKVFEKDEAKFECEVS-REPKTFR 11914
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W K + + + +L I +Y A + +S +LI+ EG
Sbjct: 11915 WLKGTQEITGDDRFELIKDGTRHSLVIKSAAFEDEAKYMFEAEDK----RTSGKLII-EG 11969
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
F PL V A E+A F ++ I V+W K+++ + + + +
Sbjct: 11970 IRLKFLT-PLKDVTAKERENAVFTVELSHDN-IPVSWFKNDQRLHTSKRVSMHDEGKTHS 12027
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
+T + DT Q A+ S A+L + E P FT KL + E + L
Sbjct: 12028 ITFKDLSIDDTSQIRVEAMGI----SSEAKLTVLEG--DPYFTGKLQDYTG-VEKDEVIL 12080
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+ ++ + V W+K+ EI P+ N I +L +KKA D G YTC D G
Sbjct: 12081 QCEISKADA-PVKWFKDGKEIKPSKNVVIKADGKKRMLILKKALKSDIGQYTC----DCG 12135
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
+ + + I++ + V + L V V E E + + + I W G + +
S Q L V V EG H+ G + W + G+ I S SF++G A L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 1308 EFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSI 1487
VTKA++G Y KA+N +G TS +++ FV QS+
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPN------------FVQRLQSM 113
Query: 1488 RVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSG 1667
V + + +V G P P VK+ + ++ I Q+GD L I + DSG
Sbjct: 114 TVRQGSQVRLQVRVTGIPTPVVKFYR-DGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSG 172
Query: 1668 LYRCVAFNKHGEIESNVNLQV 1730
Y A N G S L V
Sbjct: 173 TYSVNATNSVGRATSTAELLV 193
Score = 65.9 bits (159), Expect = 1e-10
Identities = 93/410 (22%), Positives = 162/410 (39%), Gaps = 37/410 (9%)
Frame = +3
Query: 48 LAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVS 227
+ G P V W + + A+ + ++ L+ V+ DSG+YI ENS G S
Sbjct: 21884 IKGRPAPEVKWARDHGESLDKASIES--TSSYTLLIVGNVNRFDSGKYILTVENSSG--S 21939
Query: 228 SSTFLTVQEQKLP-PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPN 404
S F+ V+ P P ++++V +T ++++W PL DG +
Sbjct: 21940 KSAFVNVRVLDTPGPPQDLKVKEVTKT---------------SVTLTW---DPPLLDGGS 21981
Query: 405 IQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPV 584
++ I + S YS ATN ++ +L EG + ++ LA
Sbjct: 21982 KIKNY--------IVEKRESTRKAYSTVATNCHKTSWKVDQL--QEGCS--YYFRVLAEN 22029
Query: 585 DAVVGESADFECHVTGTQ----------------PIKVAWAKDNREIRSGGNYQISYLEN 716
+ +G A+ V ++ + ++W K + GG+ + Y+
Sbjct: 22030 EYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHD---GGSRILGYIVE 22086
Query: 717 S----------------AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI----KERL 836
TI + +G+ + A NE G S QL++ K+ +
Sbjct: 22087 MQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGI-SDPRQLSVPVIAKDLV 22145
Query: 837 IPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALL 1016
IPP+F K L T G +++ G +V W+K+NV + T N L
Sbjct: 22146 IPPAF-KLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSL 22204
Query: 1017 LQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVT 1166
L +K A D G Y K++N AG A+ T ++++ + PP + VT
Sbjct: 22205 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVT 22254
Score = 65.1 bits (157), Expect = 2e-10
Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 4/205 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V +G++A L CQ+ G P + WY+ +L + YKM TL + D G
Sbjct: 30542 VTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEG 30601
Query: 186 EYICRAENSVGEVSSSTFLTVQ-EQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
Y C A N VGEV +S+ L +Q + P + + VG + G ++
Sbjct: 30602 VYTCIATNEVGEVETSSKLLLQATPQFHPGYPLK-EKYYGAVGSTLRLHVMYIGRPVPAM 30660
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDR-SFAGQYSCTATNPIGSASSSARLILT 539
+WF + L++ NI ++ L + R + AG+Y +N G+ + ++
Sbjct: 30661 TWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDA---ILDV 30717
Query: 540 EGRNPPFFDIPLAP--VDAVVGESA 608
E ++ P D P P ++A++ SA
Sbjct: 30718 EIQDKP--DKPTGPIVIEALLKNSA 30740
Score = 64.7 bits (156), Expect = 3e-10
Identities = 129/624 (20%), Positives = 229/624 (36%), Gaps = 45/624 (7%)
Frame = +3
Query: 3 PVKVTVGD----SASLQCQL----AGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVF 158
P KVT+ D SASL + G+ +G Y + + + T + + + V V
Sbjct: 24216 PGKVTLTDVSQTSASLMWEKPEHDGGSRVLG---YVVEMQPKGTEKWSIVAESKVCNAVV 24272
Query: 159 NQVDSNDSGEYICRAENSVGEVSSSTF---LTVQEQKLPPSFSRQLRDVQETVGLPVVFE 329
+ S ++ +A N G+ + ++ + PS G + E
Sbjct: 24273 TGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIE 24332
Query: 330 CAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGS 509
V G ++SW KDG PLK + L+I + ++ G+Y+ TATN G+
Sbjct: 24333 IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGT 24392
Query: 510 ASSSARLILTEGRNPPFFDIPLAPVDA-VVGESADFECHVTGTQPIKVAWAKDNREIRSG 686
A+ + +I+ E PP + V A V S + + G Q + + R+ +
Sbjct: 24393 ATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISN--YIVEKRDTTTT 24450
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLI--------P 842
+ +S + I K+ G Q+ +A N GK +A L+ K ++ P
Sbjct: 24451 TWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGK---SAPLDSKAVIVQYPFKEPGP 24507
Query: 843 P--------SFTKKLSETVEETEGNSFRLEG-RVAGSQPISVAWYKNNVEIHPTANCEIT 995
P S + L + E ++ G + + S+ W V+++ T +
Sbjct: 24508 PGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILW----VKLNKTPIQDTK 24563
Query: 996 FKNNALLLQVKKASMGDAGL-YTCKVSND-----AGSALCTSSIVIKEPKKPPVFDQHL- 1154
FK L D GL Y KVS + + + V ++P PP + +
Sbjct: 24564 FKTTGL----------DEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV 24613
Query: 1155 ---TPVTVS------EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVL 1307
VT+ +G V + +W+KA + S
Sbjct: 24614 ITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRY 24673
Query: 1308 EFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSI 1487
EF+ + + AG++ + S+ +G+ T++ ++ V FV E
Sbjct: 24674 EFRVIARNAAGNF-SEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLE---- 24728
Query: 1488 RVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSG 1667
A + G PIP+V W+K R+ I + L ++D +TD G
Sbjct: 24729 -----------ADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGG 24777
Query: 1668 LYRCVAFNKHGEIESNVNLQVNER 1739
Y N G + ++V +R
Sbjct: 24778 QYILKLSNVGGTKSIPITVKVLDR 24801
Score = 61.6 bits (148), Expect = 3e-09
Identities = 93/416 (22%), Positives = 158/416 (37%), Gaps = 22/416 (5%)
Frame = +3
Query: 201 AENSVGEVSSSTF---LTVQEQKLPPSF---SRQLRDVQETVGLPVVFECAVSGSEPISV 362
A N+ GE + + V+++ PP + R+ VG + + G V
Sbjct: 17191 AVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKV 17250
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+ R I + + + L I G YS T NP GS + S ++++
Sbjct: 17251 TWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLV-- 17306
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIK------VAWAKDNREIRSGGNYQIS 704
D P P D V E C++T +P+ + + R++ S +S
Sbjct: 17307 ------LDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLS 17360
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKD---SCTAQLNIKERLIPPSFTKKLSET- 872
+++G+ + A N+ G+ + + L PP K L
Sbjct: 17361 ATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVD 17420
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKN-NALLLQVKKASMGDA 1049
V++TE + + G PI+ Y + T + I FK L V G
Sbjct: 17421 VDKTEVSLVWNKPDRDGGSPIT--GYLVEYQEEGTQDW-IKFKTVTNLECVVTGLQQGKT 17477
Query: 1050 GLYTCKVSNDAGSALCTSSIVIKEPKK--PPVFD---QHLTPVTVSEGEFLQLSCHVRGS 1214
+ K N G L ++I I+ +K PP + + + + V G ++ +RG
Sbjct: 17478 YRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGV 17537
Query: 1215 EPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
+W G EIK + + N ++VL K+ + D G+Y SN AGS T
Sbjct: 17538 PVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 17593
Score = 58.5 bits (140), Expect = 2e-08
Identities = 100/486 (20%), Positives = 186/486 (38%), Gaps = 20/486 (4%)
Frame = +3
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
G +V+W KDG+ LK+ + S V +L+I + + G Y +N GS +
Sbjct: 25420 GRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVP 25479
Query: 522 ARLILTEGRNPPF-FDIPLAPVDAVV----GESADFECHVTGTQPIKVAWAKDNREIRSG 686
+I+ + PP I D++ D C ++ + + +E S
Sbjct: 25480 ITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISN-------YIVEKKETTST 25532
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI--KERLIPPS--FT 854
+ +S + I+++ G Q+ A N GK S + + + PP T
Sbjct: 25533 TWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGT 25592
Query: 855 KKLSETVEETEGNSFRLEGRVAGSQPISV-AWYKNNVEIHPTANCEITFKNNALLL---Q 1022
K+ + T ++++ GS+ I YK I + K N +L+ Q
Sbjct: 25593 PKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSI-------LWSKANKILIADTQ 25645
Query: 1023 VKKASMGDAGLYTCKV--SNDAGSALCTSS---IVIKEPKKPPVFDQHLTPVTVSEGEFL 1187
+K + + + +Y +V N AG C+ S + ++P PP +T +T
Sbjct: 25646 MKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPP-GQPEVTNITRKSVSLK 25704
Query: 1188 QLSCHVRGSEPIRIQWLKAGREIKPSD--RCSFSFANGTAVLEFKDVTKADAGDYVCKAS 1361
H G I ++ RE+ +C+++ T E ++T+ ++ A
Sbjct: 25705 WSKPHYDGGAKI-TGYIVERRELPDGRWLKCNYTNIQET-YFEVTELTEDQRYEFRVFAR 25762
Query: 1362 NVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDP 1541
N A S + S+ T +D K V ++ V++ A + G P
Sbjct: 25763 NAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLK-----INADIAGRP 25817
Query: 1542 IPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVN 1721
+P + W K ++ + R I + L ++D + D+G Y N G VN
Sbjct: 25818 LPVISWAK-DGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 25876
Query: 1722 LQVNER 1739
+V ++
Sbjct: 25877 CKVLDK 25882
Score = 57.0 bits (136), Expect = 6e-08
Identities = 70/292 (23%), Positives = 108/292 (36%), Gaps = 3/292 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VT D A CQL+ + V WY+ +++ YK ++ L+ +D EY
Sbjct: 12834 VTEFDDAVFSCQLS-REKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEY 12892
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C E+ S L V+E +P R +D+ E G VVF A + + V W
Sbjct: 12893 ACGVEDR----KSRARLFVEE--IPVEIIRPPQDILEAPGADVVF-LAELNKDKVEVQWL 12945
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
++ + G Q + L I G+Y A + AR L
Sbjct: 12946 RNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKD------KEARAKLELAAA 12999
Query: 552 PPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P I A D VV G+ + W K+N + + I
Sbjct: 13000 PK---IKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK---TIDTTAEQTS 13053
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP-PSFTKKLSETVE 878
IL+ KGD G+Y N+ GK +N+K +P P +++ET +
Sbjct: 13054 FRILEAKKGDKGRYKIVLQNKHGK--AEGFINLKVIDVPGPVRNLEVTETFD 13103
Score = 57.0 bits (136), Expect = 6e-08
Identities = 85/367 (23%), Positives = 136/367 (37%), Gaps = 21/367 (5%)
Frame = +3
Query: 336 VSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
+ G V W +D D +I+++ + L + +R +G+Y T N GS S
Sbjct: 21884 IKGRPAPEVKWARDHGESLDKASIEST--SSYTLLIVGNVNRFDSGKYILTVENSSGSKS 21941
Query: 516 SSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI---RSG 686
+ N D P P D V E +T P+ +K I R
Sbjct: 21942 AFV--------NVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRES 21993
Query: 687 GNYQISYLENSAHLTILKVDKGDTG---QYTCYAVNE--VGKDSCTAQ-LNIKERLIPPS 848
S + + H T KVD+ G + A NE +G + TA+ + ER +PP
Sbjct: 21994 TRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPG 22053
Query: 849 F---------TKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFK 1001
+ LS E +G S R+ G + Q K + + A ++T
Sbjct: 22054 KITLMDVTRNSVSLSWEKPEHDGGS-RILGYIVEMQT------KGSDKWATCATVKVTEA 22106
Query: 1002 NNALLLQVKKASMGDAGLYTCKVSNDAGSA---LCTSSIVIKEPKKPPVFDQHLTPVTVS 1172
L+Q G+ + N+ G + + ++ K+ PP F TV
Sbjct: 22107 TITGLIQ------GEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVL 22160
Query: 1173 EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVC 1352
GE L++ G + W K +K + R + ++L KD + D G YV
Sbjct: 22161 AGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVV 22220
Query: 1353 KASNVAG 1373
K +N AG
Sbjct: 22221 KLTNSAG 22227
Score = 57.0 bits (136), Expect = 6e-08
Identities = 77/356 (21%), Positives = 127/356 (35%), Gaps = 10/356 (2%)
Frame = +3
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W ++ D I+ N L+I DR+ AG+Y N GS S+ + +
Sbjct: 24056 ITWSREEGEFTDKVQIEKGV--NYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV- 24112
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAK------DNREIRSGGNYQI 701
D P P + V E + PI AK D RE +
Sbjct: 24113 -------LDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANV 24165
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET-VE 878
S + + + +G + A NE G ++ + PPS K++ T V
Sbjct: 24166 SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVS 24225
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
+T + + G V Y ++ T I ++ V S G +
Sbjct: 24226 QTSASLMWEKPEHDGGS--RVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQF 24283
Query: 1059 TCKVSNDAGSA---LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRI 1229
K N+ G + + ++ K+ P ++ GE L++ V G I
Sbjct: 24284 RVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNI 24343
Query: 1230 QWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
W+K G +K + R + + VL K+ K D G Y A+N AG+ T V
Sbjct: 24344 SWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 24399
Score = 56.6 bits (135), Expect = 8e-08
Identities = 61/240 (25%), Positives = 91/240 (37%), Gaps = 16/240 (6%)
Frame = +3
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLP--------PSFSRQLRDVQETVGLPVVFECAVS 341
E+ + EN GE S + + E P P F +LR++ C V+
Sbjct: 30896 EFRVKCENLGGE---SEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVT 30952
Query: 342 GSEPISVSWFKDGRPL-KDGPNIQTS-FLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
G V W++ G+ + DG + F L I A Y ATN GS S
Sbjct: 30953 GHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVS 31012
Query: 516 SSARLILTEGRNPPFFDIP-----LAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIR 680
+A L E P +P + V A+ GE + +G + W K I
Sbjct: 31013 GTASL---EVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLID 31069
Query: 681 SGGNYQISYLENSAHLTILK-VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK 857
+ G+YQ+ + L V++ D G Y A N G D T +L++ + PP K
Sbjct: 31070 NNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVK 31129
Score = 56.2 bits (134), Expect = 1e-07
Identities = 32/87 (36%), Positives = 44/87 (50%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G + L + G P VSW K T L+P KM + N+ TL V+ DSG+Y
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 19366
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPS 272
AENS G S++ L V ++ PP+
Sbjct: 19367 TITAENSSGSKSATIKLKVLDKPGPPA 19393
Score = 56.2 bits (134), Expect = 1e-07
Identities = 41/133 (30%), Positives = 60/133 (45%), Gaps = 3/133 (2%)
Frame = +3
Query: 777 AVNEVGKDS-CTAQLNIKERLIPP--SFTKKLSETVEETEGNSFRLEGRVAGSQPISVAW 947
A + K S T + K+ + P S K +T+ G +FRLE V G ++ W
Sbjct: 23600 AAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW 23659
Query: 948 YKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPK 1127
+ + EI +A CEI + LL VK A D G Y + SN AGS ++ + +
Sbjct: 23660 LRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP 23719
Query: 1128 KPPVFDQHLTPVT 1166
PP +T VT
Sbjct: 23720 GPPEGPVQVTGVT 23732
Score = 54.7 bits (130), Expect = 3e-07
Identities = 83/369 (22%), Positives = 131/369 (35%), Gaps = 22/369 (5%)
Frame = +3
Query: 336 VSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
VSG P +V+W + R L I+T+ + + ++ I RS G YS A N G
Sbjct: 16548 VSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVYSLLAKNEAGERK 16605
Query: 516 SSARLILTEGRNP---PFFDIPLAPVDAVVGESAD---FECHVTGTQPIKVAWAKDNREI 677
+ + + + P PF + ES F G PI + + RE
Sbjct: 16606 KTIIVDVLDVPGPVGTPFL------AHNLTNESCKLTWFSPEDDGGSPI-TNYVIEKRES 16658
Query: 678 RSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKD---SCTAQLNIKERLIPPS 848
++Y + T+ + +G + A N +G + L I+E + P
Sbjct: 16659 DRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPE 16718
Query: 849 FTKKLSETVEETEGNSFRLEGRV----AGSQPISVAWYKNNV---EIHPTANCEITFKNN 1007
+ L V+E N+ L GS+ I+ + + H N + +
Sbjct: 16719 RPEDLE--VKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKY 16776
Query: 1008 ALLLQVKKASMGDAGLYTCKVSNDAGS---ALCTSSIVIKEPKKPPVFDQHLT---PVTV 1169
VK GD Y N G + CT I K+ PP HL +T+
Sbjct: 16777 T----VKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTL--HLDFRDKLTI 16830
Query: 1170 SEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYV 1349
GE L+ G ++ W K ++ DR T LE ++D+G Y
Sbjct: 16831 RVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYC 16890
Query: 1350 CKASNVAGS 1376
N GS
Sbjct: 16891 VVVENSTGS 16899
Score = 54.7 bits (130), Expect = 3e-07
Identities = 34/111 (30%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Frame = +3
Query: 240 LTVQEQKLPPSFS-----RQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPN 404
+T+ + +PP + L V+ G V + V G +VSW KDG LK
Sbjct: 19284 VTILAENVPPRIDLSVAMKSLLTVK--AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEG 19341
Query: 405 IQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
I+ + N+ TL +F +R +G Y+ TA N GS S++ +L + + PP
Sbjct: 19342 IKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPP 19392
Score = 54.3 bits (129), Expect = 4e-07
Identities = 49/225 (21%), Positives = 93/225 (41%), Gaps = 9/225 (4%)
Frame = +3
Query: 147 TLVFNQVDSNDSGE---YICRAENSVGEVS---SSTFLTVQEQKLPPSFSRQL---RDVQ 299
T++ + V S + GE + RA+N G + T +TVQ+ ++ P+ + +
Sbjct: 29690 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIH 29749
Query: 300 ETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQY 479
G PV ++G P + SWF G L++ + VA L I +T G+Y
Sbjct: 29750 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEY 29809
Query: 480 SCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWA 659
+ N G+ S + ++I+ + PP I + +DA + + G P+ +
Sbjct: 29810 TLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLS-GYV 29868
Query: 660 KDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVG 794
+ R+ G +S + ++ +G+ + A N G
Sbjct: 29869 VEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFG 29913
Score = 53.5 bits (127), Expect = 7e-07
Identities = 32/100 (32%), Positives = 46/100 (46%)
Frame = +3
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ ++V K+P P D + V EGE L + R + W K G+E+K SDR +
Sbjct: 14375 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 14434
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
+ +A LE +ADAG Y N GS T+ V
Sbjct: 14435 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINV 14474
Score = 53.5 bits (127), Expect = 7e-07
Identities = 61/254 (24%), Positives = 102/254 (40%), Gaps = 23/254 (9%)
Frame = +3
Query: 474 QYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVA 653
Q+ A N G +S S +P F + ++PVD + D+ VT + I +
Sbjct: 27828 QFRVYAENSAGLSSPS---------DPSKFTLAVSPVDPP--GTPDY-IDVT-RETITLK 27874
Query: 654 WAKDNREIRSGGNYQISYL-----------------ENSAHLTILKVDKGDTGQYTCYAV 782
W N +R GG+ + Y + T+ + GD ++ A
Sbjct: 27875 W---NPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIAR 27931
Query: 783 NEVGKDSCTAQ----LNIKERLIPP--SFTKKLSETVEETEGNSFRLEGRVAGSQPISVA 944
N VG S +Q + ++ +PP F + + + G S R++ V G V
Sbjct: 27932 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 27991
Query: 945 WYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEP 1124
W+K+ VEI N EIT + L V+ A+ G+YT + N +GSA + +++
Sbjct: 27992 WFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDT 28051
Query: 1125 KKPPVFDQHLTPVT 1166
V T +T
Sbjct: 28052 PGKVVGPIRFTNIT 28065
Score = 52.8 bits (125), Expect = 1e-06
Identities = 91/418 (21%), Positives = 149/418 (35%), Gaps = 41/418 (9%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVAT---LVFNQVDSN 176
+++ G + + + G P W K + +L +NV T L+
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVI----DNVGTKSELIIKDALRK 15169
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
D G Y+ A NS G F+ +V + G + + V+ +
Sbjct: 15170 DHGRYVITATNSCGS----------------KFAAARVEVFDVPGPVLDLKPVVTNRKMC 15213
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNI------FQTDRSFAGQYSCTATNPIGSASS 518
++W P DG + T F+ + +T+RS C T +
Sbjct: 15214 LLNW---SDPEDDGGSEITGFIIERKDAKMHTWRQPIETERS-----KCDITGLLEGQEY 15265
Query: 519 SARLILTE--GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
R+I G PP P+ VD + G E +T T+ K D +E RS G
Sbjct: 15266 KFRVIAKNKFGCGPPVEIGPILAVDPL-GPPTSPE-RLTYTERTKSTITLDWKEPRSNGG 15323
Query: 693 YQIS--YLENSAH-----------------LTILKVDKGDTGQYTCYAVNEVGKDSCTAQ 815
I +E H + +D+ ++ AVNE+G+ +
Sbjct: 15324 SPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLP 15383
Query: 816 LN--IKERLIPPSFTKKLS---ETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIH-PT 977
LN I++ +PP+ +LS +T++ G + V G + W KN I PT
Sbjct: 15384 LNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPT 15443
Query: 978 ANCEITFKNNALL-----LQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 1136
+IT + + L + KA D G YT SN GS + + + PP
Sbjct: 15444 DALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPP 15501
Score = 52.8 bits (125), Expect = 1e-06
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
Frame = +3
Query: 807 TAQLNIKERLIPP--SFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTA 980
T + ++ + PP S K +T+ G SF+++ + G ++ W K + E+ TA
Sbjct: 22529 TGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTA 22588
Query: 981 NCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 1136
EI + A L VK A D+G Y K N AG T ++ + + PP
Sbjct: 22589 RLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPP 22640
Score = 52.0 bits (123), Expect = 2e-06
Identities = 32/103 (31%), Positives = 50/103 (48%)
Frame = +3
Query: 858 KLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKAS 1037
K +TV G +FRLE V+G P ++ W K+ E+ TA EI + + L K ++
Sbjct: 21466 KFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDST 21525
Query: 1038 MGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVT 1166
D+G YT +N G A ++ + + PP +T VT
Sbjct: 21526 RRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVT 21568
Score = 50.4 bits (119), Expect = 6e-06
Identities = 112/537 (20%), Positives = 185/537 (34%), Gaps = 46/537 (8%)
Frame = +3
Query: 201 AENSVGEVSSSTF-LTVQEQKLPPSFSRQL--RDVQET-VGLPVVFECAVSGSEPISVSW 368
A +SV E S ST + V++ PP + RDV G + ++G +SW
Sbjct: 25764 AADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISW 25823
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
KDG +++ + DN L + R GQY T N G+ S + + +
Sbjct: 25824 AKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKP 25883
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP + E + + ++W + + + +Y I ++HL
Sbjct: 25884 GPP---------------AGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHL 25928
Query: 729 T--------------ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKER-----LIPPSF 851
+ K+ KG+ + VN+ G + IK PP+
Sbjct: 25929 AWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTS 25988
Query: 852 TKKLSETVE---------ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKN 1004
+ S T E E++G S + + S+ W + N K
Sbjct: 25989 LEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVN-------------KK 26035
Query: 1005 NALLLQVKKASMGDAGLYTCKV--SNDAGSALC--TSSIVIKE--------PKKPPVFDQ 1148
L+VK + + Y +V N AG +L TS ++ E P KP + D
Sbjct: 26036 PVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDS 26095
Query: 1149 HLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTK 1328
T +T++ + L G PI ++ + + S GT T
Sbjct: 26096 GKTTITIAWVKPL-----FDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTG 26150
Query: 1329 ADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTT 1508
A+ V + V SD S S + LF + ++ K
Sbjct: 26151 AEYVFRVKSVNKVGASDPSDSS---------DPQIAKEREEEPLFDIDSEMRKTLIVKAG 26201
Query: 1509 ATFIAKV--GGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLY 1673
A+F V G P+PNV W+K + R ++ L I + + DSG Y
Sbjct: 26202 ASFTMTVPFRGRPVPNVLWSK---PDTDLRTRAYVDTTDSRTSLTIENANRNDSGKY 26255
Score = 50.1 bits (118), Expect = 8e-06
Identities = 78/375 (20%), Positives = 137/375 (36%), Gaps = 21/375 (5%)
Frame = +3
Query: 336 VSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
+ G V W K ++D I + + +L + +R +G+Y+ T N G+ S
Sbjct: 22966 IKGRPTPEVKWGKVDGEIRDAAIIDVT--SSFTSLVLDNVNRYDSGKYTLTLENSSGTKS 23023
Query: 516 SSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI---RSG 686
+ + + D P PV+ V E +T P+ +K I R
Sbjct: 23024 AFVTVRV--------LDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREA 23075
Query: 687 GNYQISYLENSAHLTILKVDKGDTG---QYTCYAVNE--VGKDSCTAQ-LNIKERLIPPS 848
+ + + H K+D+ G + A NE +G + TA + + E PP
Sbjct: 23076 TRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPG 23135
Query: 849 FTKKLSETVEETEGNSFRLEGRV----AGSQPISVAWYKNNVEIHPTANCEITFKNNALL 1016
TV++ NS L GS+ I + C + +L
Sbjct: 23136 -----KITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA---RVKSLQ 23187
Query: 1017 LQVKKASMGDAGLYTCKVSNDAGSA--------LCTSSIVIKEPKKPPVFDQHLTPVTVS 1172
+ + G+ L+ N+ G + + +VI EP P F + +V
Sbjct: 23188 AVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVI-EPDVKPAFSSY----SVQ 23242
Query: 1173 EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVC 1352
G+ L++ + G I W K G +K + R + + + L K+ K D G Y
Sbjct: 23243 VGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGI 23302
Query: 1353 KASNVAGSDTSKSKV 1397
+NV G T+ ++
Sbjct: 23303 TVANVVGQKTASIEI 23317
>ref|NP_114141.2| hemicentin-1 precursor [Homo sapiens].
Length = 5635
Score = 186 bits (471), Expect = 9e-47
Identities = 156/576 (27%), Positives = 236/576 (40%), Gaps = 3/576 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V V + L+C+ AG P ++WYK D +L +T M F N + +D+G Y
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWYK-DNRLLSGST-SMTFLNRGQIIDIESAQISDAGIY 1989
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A NS G ++ F ++Q + PS S V V PV EC G S++W
Sbjct: 1990 KCVAINSAG--ATELFYSLQVH-VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWL 2046
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDG P+ N L L + S G+Y+C A N G L +
Sbjct: 2047 KDGSPVSSFSN-GLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV--- 2102
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP V ++ ++ + C P + W KD + IS EN + L
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSIS--ENRSVLK 2160
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF--TKKLSETVEETEGNSFRL 905
I DTG+YTC A N GK +NI +PP+ + +L++ + EGN L
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNI---WVPPNIGGSDELTQ-LTVIEGNLISL 2216
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+G P ++ W K + + + + LQ+ A DA LY+C SN AG
Sbjct: 2217 LCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
+A ++ + H T + V+ G+ + L C V+G P + W+K G + +
Sbjct: 2277 TAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKA 2336
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ +L+ K++ +D G YVC A NVAG K ++
Sbjct: 2337 K--GVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNH---- 2390
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWR-QLNQGGRIFIHQKGD 1622
P++I VVEK + + + G P+P++ W K W L+ RI
Sbjct: 2391 --------RSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRIL----SG 2438
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
L + TT D+G Y CV N GE L V
Sbjct: 2439 GRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSV 2474
Score = 178 bits (451), Expect = 2e-44
Identities = 144/581 (24%), Positives = 249/581 (42%), Gaps = 5/581 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G S SL+C+ P ++WYK + T + + + L + + +D+G
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMI--TESTHVEILADGQMLHIKKAEVSDTG 3126
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDV-QETVGLPVVFECAVSGSEPISV 362
+Y+CRA N G + L V +PPS R+V ET+ PV C +G P ++
Sbjct: 3127 QYVCRAINVAGRDDKNFHLNVY---VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTI 3183
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+ + +++ +++ L + L I ++ S +G Y+C A+N G A L +
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQV 3243
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ +IP + V ++GE+ + C+ G + W KD + I SG +I N +
Sbjct: 3244 PPSVAGAEIP-SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS 3302
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF--TKKLSETVEETEGNS 896
L I DTG+YTC A N G++ LN+ + P+ K +E + S
Sbjct: 3303 TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNV---YVTPTIRGNKDEAEKLMTLVDTS 3359
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
+E R G+ P + W KN + + +++ + ++++ +A + D +YTC SN
Sbjct: 3360 INIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASN 3417
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHL--TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
AG + + PP D + +TV +G ++C G+ + WL+ G+
Sbjct: 3418 RAG---VDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQ 3474
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
+ + S VL+ D+G Y C ASN AG + SK +
Sbjct: 3475 PLGLDAHLTVS--THGMVLQLLKAETEDSGKYTCIASNEAG-EVSKHFI--------LKV 3523
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
++G E + I V+ G P P + W K R L Q + +
Sbjct: 3524 LEPPHINGS----EEHEEISVIVNNPLELTCIASGIPAPKMTWMK-DGRPLPQTDQ--VQ 3576
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
G L I D+G Y C+A + G+ + ++V+
Sbjct: 3577 TLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVH 3617
Score = 174 bits (440), Expect = 4e-43
Identities = 157/606 (25%), Positives = 248/606 (40%), Gaps = 11/606 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + +L C++ GTP + WYK + ++ ++T + NN L + D+G
Sbjct: 1370 VSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTV--NNGKILKLFRATPEDAG 1427
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C+A N G +S + + + +PP+ + +V + V EC V G+
Sbjct: 1428 RYSCKAINIAG--TSQKYFNI-DVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD 1484
Query: 360 VSWFKDGRPLKDG-PNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
+ WFKDG+PL G PN++ LD L++ R+ G+Y CT +N G + +L +
Sbjct: 1485 IHWFKDGKPLFLGDPNVE--LLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Query: 537 -----TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
+G N + ++ EC G + W KD + I S Q
Sbjct: 1543 YIPPSIKGGNVT------TDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS--QA 1594
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
Y++ +L I + D+ YTC+ N G + +++ +PP L+ + +
Sbjct: 1595 LYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV---YVPPMIEGNLATPLNK 1651
Query: 882 TE--GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGL 1055
+S LE + AG+ + W K+ V + AN I + L++ A D G
Sbjct: 1652 QVVIAHSLTLECKAAGNPSPILTWLKDGVPVK--ANDNIRIEAGGKKLEIMSAQEIDRGQ 1709
Query: 1056 YTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQW 1235
Y C ++ AG + + P D+ + V L+L CHV GS P I W
Sbjct: 1710 YICVATSVAGEKEIKYEVDVLVPPAIEGGDE-TSYFIVMVNNLLELDCHVTGSPPPTIMW 1768
Query: 1236 LKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXX 1415
LK G+ I +R F L ++ G Y C A+N AG + +VT
Sbjct: 1769 LKDGQLI--DERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVT----- 1821
Query: 1416 XXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKV-GGDPIPNVKWTKGKWRQLNQG 1592
V S S RVV K + + G P P++ W K
Sbjct: 1822 ----------VHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQ 1871
Query: 1593 GRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLR 1772
G + I G L+I T D+G Y CVA N GE + ++ L V+E E D
Sbjct: 1872 GNLKIQSSG--RVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLE----DAG 1925
Query: 1773 AMLKKT 1790
ML +T
Sbjct: 1926 KMLNET 1931
Score = 167 bits (423), Expect = 3e-41
Identities = 158/604 (26%), Positives = 252/604 (41%), Gaps = 5/604 (0%)
Frame = +3
Query: 3 PVKVTV--GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSN 176
PV+++V G+ +L C++ P ++W K + P + H ++ + ++
Sbjct: 1086 PVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSP--RHTFLPSGSMKITETRTS 1143
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
DSG Y+C A N G V+ + L V +PP R + ++ VG V C G+
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVH---VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
++W K G + S D TL+I Q S AG Y+C ATN G+ + L +
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITLHV 1258
Query: 537 TEGRNPPFFDIPLAPV--DAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
E + P + V + +F C GT + W + RE+ +G IS L
Sbjct: 1259 QEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISIL 1317
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEG 890
E+ L I V D G+Y C AVNE G + + N+K + P K+ V
Sbjct: 1318 EDGTLLVIASVTPYDNGEYICVAVNEAG--TTERKYNLKVHVPPVIKDKEQVTNVSVLLN 1375
Query: 891 NSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
L V G+ + WYK+NV++ T + I NN +L++ +A+ DAG Y+CK
Sbjct: 1376 QLTNLFCEVEGTPSPIIMWYKDNVQV--TESSTIQTVNNGKILKLFRATPEDAGRYSCKA 1433
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
N AG++ +I + P P + + V+V + L C V+G+ I W K G
Sbjct: 1434 INIAGTSQKYFNIDVLVP--PTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDG 1491
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
+ + D + + VL K+ + D G Y C SN AG K+T
Sbjct: 1492 KPLFLGDP-NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT--------- 1541
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
+ + + I V+ + + G P+P + W K ++ ++I
Sbjct: 1542 ----IYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYI 1597
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKK 1787
KG L I +DS Y C N G E + ++ V IEG+L L K
Sbjct: 1598 -DKGQ--YLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV---YVPPMIEGNLATPLNK 1651
Query: 1788 TPVL 1799
V+
Sbjct: 1652 QVVI 1655
Score = 167 bits (423), Expect = 3e-41
Identities = 153/575 (26%), Positives = 230/575 (40%), Gaps = 8/575 (1%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENS 212
+LQC G P ++W K D + TA + +++ L + D+G Y C A N+
Sbjct: 1845 ALQCIANGIPNPSITWLKDDQPVN-TAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNA 1903
Query: 213 VGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGL--PVVFECAVSGSEPISVSWFKDGRP 386
GE L V E PPS + + ETV + PV EC +G+ ++W+KD R
Sbjct: 1904 AGETQQHIQLHVHE---PPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRL 1960
Query: 387 LKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFD 566
L ++ +FL+ ++I S AG Y C A N SA ++ + P
Sbjct: 1961 LSGSTSM--TFLNRGQIIDIESAQISDAGIYKCVAIN---SAGATELFYSLQVHVAPSIS 2015
Query: 567 IPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVD 746
V VV EC G + W KD + S N + L L +
Sbjct: 2016 GSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSGGRILALTSAQ 2074
Query: 747 KGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGS 926
DTG+YTC AVN G+ L + +PP+ + + V + L +
Sbjct: 2075 ISDTGRYTCVAVNAAGEKQRDIDLRV---YVPPNIMGE-EQNVSVLISQAVELLCQSDAI 2130
Query: 927 QPISVAWYKNNVEIHPTANCE-ITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTS 1103
P ++ W K+ HP ++ N +L+++ A + D G YTC+ +N AG
Sbjct: 2131 PPPTLTWLKDG---HPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNY 2187
Query: 1104 SIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFS 1283
++ I P D+ LT +TV EG + L C G P + W K G +
Sbjct: 2188 NVNIWVPPNIGGSDE-LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVR 2246
Query: 1284 FANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLF 1463
+G L+ K+DA Y C ASNVAG T+K +
Sbjct: 2247 ILSGGRQLQISIAEKSDAALYSCVASNVAG--TAKKEYNLQVYIRPTITNSG-------- 2296
Query: 1464 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAK---- 1631
S P I V + + +V G P P V W K G I KG E
Sbjct: 2297 --SHPTEIIVTRGKSISLECEVQGIPPPTVTWMK--------DGHPLIKAKGVEILDEGH 2346
Query: 1632 -LEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
L++++ +D+G Y CVA N G + +L V+
Sbjct: 2347 ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVH 2381
Score = 166 bits (419), Expect = 1e-40
Identities = 155/601 (25%), Positives = 239/601 (39%), Gaps = 26/601 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VKV S +L C++ G P ++W+K L+ + H + L V +G
Sbjct: 2489 VKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAH--HIISGGRFLQITNVQVPHTG 2546
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFS-----RQLRDVQETVGLPVVFECAVSGSE 350
Y C A + G S S L V + P+ + DV + P C
Sbjct: 2547 RYTCLASSPAGHKSRSFSLNV---FVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYP 2603
Query: 351 PISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
P +++WFKDG PL+ NI+ L TL I AG+YSC ATN G +
Sbjct: 2604 PATITWFKDGTPLESNRNIR--ILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEV 2661
Query: 531 ------ILTEGRNPPFFDIPLAP--VDAVVGESADFECHVTGTQPIKVAWAKDNREIRSG 686
I+ +G + L+P V V + EC ++W KD + ++S
Sbjct: 2662 KVYIPPIINKG---DLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD 2718
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK--- 857
+ I+ N L I + DTG+YTC A N G+D +NI+ +PPSF K
Sbjct: 2719 DHVNIA--ANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ---VPPSFQKLWE 2773
Query: 858 --------KLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHP-TANCEITFKNNA 1010
+ E + N L + P ++ WYK+ HP T++ ++
Sbjct: 2774 IGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDG---HPLTSSDKVLILPGG 2830
Query: 1011 LLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFL 1187
+LQ+ +A + DAG YTC N+AG + + P + L VTV +
Sbjct: 2831 RVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSA 2890
Query: 1188 QLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNV 1367
+ C GS R W K G+ + D F +NG +L+ + D G YVC A N
Sbjct: 2891 LIECLSSGSPAPRNSWQKDGQPLLEDDHHKF-LSNG-RILQILNTQITDIGRYVCVAENT 2948
Query: 1368 AGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIP 1547
AGS + + +++ VV + +V G P P
Sbjct: 2949 AGSAKKYFNLNVHVPPSVIG--------------PKSENLTVVVNNFISLTCEVSGFPPP 2994
Query: 1548 NVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
++ W K + + + I G L+I +D G Y C+A N+ GE + +L
Sbjct: 2995 DLSWLKNE-QPIKLNTNTLIVPGG--RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLT 3051
Query: 1728 V 1730
V
Sbjct: 3052 V 3052
Score = 163 bits (412), Expect = 6e-40
Identities = 142/583 (24%), Positives = 226/583 (38%), Gaps = 8/583 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYK--MHFRNNVATLVFNQVDSND 179
V V V + L+C+ G P ++W K + P +++ + + L +D
Sbjct: 2021 VAVVVNNPVRLECEARGIPAPSLTWLKDGS---PVSSFSNGLQVLSGGRILALTSAQISD 2077
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
+G Y C A N+ GE L V +PP+ + ++V + V C P +
Sbjct: 2078 TGRYTCVAVNAAGEKQRDIDLRVY---VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPT 2134
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W KDG PL P + S +N + L I G+Y+C ATN G + + +
Sbjct: 2135 LTWLKDGHPLLKKPGLSIS--ENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
N D L + + G C +G P + W K + + ++ L
Sbjct: 2193 VPPNIGGSD-ELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGG 2251
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE--ETEGN 893
L I +K D Y+C A N G L + I P+ T S E T G
Sbjct: 2252 RQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV---YIRPTITNSGSHPTEIIVTRGK 2308
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCE-ITFKNNALLLQVKKASMGDAGLYTCKV 1070
S LE V G P +V W K+ HP + + + +LQ+K + D G Y C
Sbjct: 2309 SISLECEVQGIPPPTVTWMKDG---HPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2365
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFDQHLTP--VTVSEGEFLQLSCHVRGSEPIRIQWLKA 1244
N AG + + P P + H +P ++V E + L+C G I W K
Sbjct: 2366 VNVAGMTDKKYDLSVHAP--PSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKD 2423
Query: 1245 GREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXX 1424
G + S+ S +G +L T DAG Y C N AG +
Sbjct: 2424 GWPVSLSN--SVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERK------------- 2468
Query: 1425 XXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQLNQGGRI 1601
V + + + ++V EK + T +V G+P+P + W K G+ Q ++ I
Sbjct: 2469 IFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHI 2528
Query: 1602 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
L+I + +G Y C+A + G + +L V
Sbjct: 2529 I----SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 160 bits (405), Expect = 4e-39
Identities = 155/598 (25%), Positives = 252/598 (42%), Gaps = 15/598 (2%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V +GD ++C+ +G P V W+KGD +LRP+ + + L + D+G+Y
Sbjct: 713 VALGDITVMECKTSGIPPPQVKWFKGDLELRPSTF--LIIDPLLGLLKIQETQDLDAGDY 770
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A N G + L V PP F ++ DV +G V C V G ++ W
Sbjct: 771 TCVAINEAGRATGKITLDVGS---PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWR 827
Query: 372 K-DGRPLKDGPNIQTSFLDNVAT-----LNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
+ D P+ P S + + T LN++ +D+ G Y C A N G S +
Sbjct: 828 RLDNMPIFSRP-FSVSSISQLRTGALFILNLWASDK---GTYICEAENQFGKIQSETTVT 883
Query: 534 LTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPI-KVAWAKDNREIRSGGNYQISYL 710
+T G P I + + + G+ C + PI + W K++ + N I+ +
Sbjct: 884 VT-GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ--NPYIT-V 939
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEG 890
+ L I +V D G+YTC A N G ++ T + + ++P + + + EG
Sbjct: 940 RSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV--HVLPT--IQHGQQILSTIEG 995
Query: 891 NSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
L + +G+ SV W K E+ T++ + + + L V ++G Y C
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADGSLYVVSPGG-EESGEYVCTA 1053
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVF-DQH------LTPVTVSEGEFLQLSCHVRGSEPIRI 1229
+N AG A + + +P VF DQ ++V GE + L C V+ P I
Sbjct: 1054 TNTAGYA--KRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPII 1111
Query: 1230 QWLKAGREIKP-SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXX 1406
W K + I P S R +F + + E + +D+G Y+C A+N+AG+ T K+
Sbjct: 1112 TWAKETQLISPFSPRHTFLPSGSMKITETR---TSDSGMYLCVATNIAGNVTQAVKLN-- 1166
Query: 1407 XXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLN 1586
V K+ P+ ++V G P+P + W+KG L
Sbjct: 1167 -----------VHVPPKI--QRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLV 1213
Query: 1587 QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIE 1760
G H + L I T +D+G+Y CVA N G E+ + L V E E +E
Sbjct: 1214 DGEH---HVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLE 1268
Score = 160 bits (404), Expect = 5e-39
Identities = 160/603 (26%), Positives = 239/603 (39%), Gaps = 17/603 (2%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDS---NDS 182
+ + S L+C G P ++W K L H R ++ F + S D+
Sbjct: 3724 ILLNKSTVLECIAEGVPTPRITWRKDGAVLAGN-----HARYSILENGFLHIQSAHVTDT 3778
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y+C A N+ G L V +PPS + ++ V + C +G S+
Sbjct: 3779 GRYLCMATNAAGTDRRRIDLQVH---VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSI 3835
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+G L N + L + +L I Y CT TN G + L +
Sbjct: 3836 NWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTV-- 3893
Query: 543 GRNPPFFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDN-REIRSGGNYQISYLE 713
+ PP I P D +V + A C +G + W K+ R + G Y+I
Sbjct: 3894 -QVPP--SIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRIL--- 3947
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN 893
+S + IL G+YTC A N G L++ E PP + SE + N
Sbjct: 3948 SSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE---PPVIQPQPSE-LHVILNN 4003
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALL----LQVKKASMGDAGLYT 1061
L G+ + W K + ++ + +N+A+L LQ+ +A DAG Y
Sbjct: 4004 PILLPCEATGTPSPFITWQKEGINVNTSG------RNHAVLPSGGLQISRAVREDAGTYM 4057
Query: 1062 CKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLK 1241
C N AG+AL + ++ P PV HL ++ + + LSC G P I W K
Sbjct: 4058 CVAQNPAGTALGKIKLNVQVP---PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHK 4114
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
GR I S R ++G+ + F V DAG Y C A+NVAGS ++ +K+T
Sbjct: 4115 DGRAIVESIRQRV-LSSGSLQIAF--VQPGDAGHYTCMAANVAGSSSTSTKLT------- 4164
Query: 1422 XXXXXXXXVDGKLFFVSEPQSIR-------VVEKTTATFIAKVGGDPIPNVKWTKGKWRQ 1580
V P IR V E + A G P P + W K
Sbjct: 4165 ---------------VHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL 4209
Query: 1581 LNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIE 1760
N G+ G+ L + + DSG Y CVA N GE V+L V+ ++
Sbjct: 4210 ANLLGKYTAEPYGE---LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELP 4266
Query: 1761 GDL 1769
GD+
Sbjct: 4267 GDV 4269
Score = 155 bits (393), Expect = 1e-37
Identities = 157/622 (25%), Positives = 241/622 (38%), Gaps = 27/622 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + SL C+ P ++W+K T L ++ TL +++G
Sbjct: 2585 VTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI--LPGGRTLQILNAQEDNAG 2642
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSR--------QLRDVQETVGLPVVFECAVS 341
Y C A N GE+ + V +PP ++ ++V+ V + EC
Sbjct: 2643 RYSCVATNEAGEMIKHYEVKVY---IPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAY 2699
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS-- 515
S+SW+KDG+PLK ++ + N TL I + S G+Y+C A+N G
Sbjct: 2700 AIPSASLSWYKDGQPLKSDDHVNIAA--NGHTLQIKEAQISDTGRYTCVASNIAGEDELD 2757
Query: 516 ---------SSARL-----ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVA 653
S +L +L GRN D+ ++ C P +
Sbjct: 2758 FDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDV-------IINNPISLYCETNAAPPPTLT 2810
Query: 654 WAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKER 833
W KD + S I L L I + D G+YTC AVNE G+DS + +
Sbjct: 2811 WYKDGHPLTSSDKVLI--LPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV--- 2865
Query: 834 LIPPSFTKKLSETVEETE---GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKN 1004
L+PP S+ EE S +E +GS +W K+ + + F +
Sbjct: 2866 LVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL--LEDDHHKFLS 2923
Query: 1005 NALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEF 1184
N +LQ+ + D G Y C N AGSA ++ + P P V +TV F
Sbjct: 2924 NGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVP--PSVIGPKSENLTVVVNNF 2981
Query: 1185 LQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASN 1364
+ L+C V G P + WLK + IK + + G L+ +D G+Y C A N
Sbjct: 2982 ISLTCEVSGFPPPDLSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Query: 1365 VAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPI 1544
AG K +T D + V + V E T+ + + P
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKDH------DSESLSV-----VNVREGTSVSLECESNAVPP 3088
Query: 1545 PNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNL 1724
P + W K R + + + I D L I+ +D+G Y C A N G + N +L
Sbjct: 3089 PVITWYK-NGRMITESTHVEI--LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHL 3145
Query: 1725 QVNERKKQEKIEGDLRAMLKKT 1790
V IEG R ++ +T
Sbjct: 3146 NV---YVPPSIEGPEREVIVET 3164
Score = 154 bits (390), Expect = 2e-37
Identities = 144/571 (25%), Positives = 219/571 (38%), Gaps = 4/571 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V V +L C+ G P+ ++W K L + + +LV +D+ Y
Sbjct: 3815 VIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATY 3874
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C N G+ + LTVQ +PPS + + D T P V C SG S+ W
Sbjct: 3875 ECTVTNGAGDDKRTVDLTVQ---VPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT 3931
Query: 372 KDG---RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
K+G P DG I +S + I T + AG+Y+C A N GSA L + E
Sbjct: 3932 KNGIRLLPRGDGYRILSS-----GAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE 3986
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIR-SGGNYQISYLENS 719
PP + + ++ C TGT + W K+ + SG N+ + S
Sbjct: 3987 ---PPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVL---PS 4040
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I + + D G Y C A N G +LN++ +PP + L E V +
Sbjct: 4041 GGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ---VPPVISPHLKEYVIAVD-KPI 4096
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L G P + W+K+ I + + + LQ+ GDAG YTC +N
Sbjct: 4097 TLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANV 4153
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS+ ++ + + P + + H TV+E L C G I W K +
Sbjct: 4154 AGSSSTSTKLTVHVPPRIRSTEGH---YTVNENSQAILPCVADGIPTPAINWKK--DNVL 4208
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
++ A L ++V D+G Y C A+N AG DT +T
Sbjct: 4209 LANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPT------- 4261
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
F P + + + K G P+P + WT N
Sbjct: 4262 --------FTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN-----NNIIPAHFDSVN 4308
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIES 1712
++L I +K DSG Y C A N G +++
Sbjct: 4309 GHSELVIERVSKEDSGTYVCTAENSVGFVKA 4339
Score = 153 bits (386), Expect = 6e-37
Identities = 144/582 (24%), Positives = 232/582 (39%), Gaps = 7/582 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V V + SL C+++G P +SW K + ++ + ++ +V +D GEY
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKV--SDGGEY 3033
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSF----SRQLRDVQETVGLPVVFECAVSGSEPIS 359
C A N GE LTV +PPS S L V G V EC + P
Sbjct: 3034 TCIAINQAGESKKKFSLTVY---VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W+K+GR + + +++ L + L+I + + S GQY C A N G + L +
Sbjct: 3091 ITWYKNGRMITESTHVE--ILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY 3148
Query: 540 EGRNPPFFDIPLAPVDA-VVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
PP + P V + C TG P +AW K+++ I + + ++ L
Sbjct: 3149 V---PPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG 3205
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKLSETVEETEGN 893
+ L I + D+G YTC A N GK L+I+ +PPS ++ V G
Sbjct: 3206 GSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQ---VPPSVAGAEIPSDVSVLLGE 3262
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
+ L G + W K+ I I N L + A D G YTC +
Sbjct: 3263 NVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVAT 3322
Query: 1074 NDAGSALCTSSI-VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
N AG ++ V P D+ +T+ + + + C G+ P +I WLK G
Sbjct: 3323 NPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTS-INIECRATGTPPPQINWLKNGL 3381
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
+ S A V+ +D Y C ASN AG D +
Sbjct: 3382 PLPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPN---- 3435
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
+D + + I V++ ++ + G P P++ W + + L + +
Sbjct: 3436 -----MDNSM----GTEEITVLKGSSTSMACITDGTPAPSMAWLRDG-QPLGLDAHLTVS 3485
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
G L++ DSG Y C+A N+ GE+ + L+V E
Sbjct: 3486 THG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLE 3525
Score = 152 bits (383), Expect = 1e-36
Identities = 149/600 (24%), Positives = 232/600 (38%), Gaps = 24/600 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ V +S SL C+ +G P ++W+K + + + ++ + L+ Q D+G
Sbjct: 2396 ISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLM--QTTMEDAG 2453
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPIS 359
+Y C N+ GE L+V +PP L DV+ V C V+G+
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSV---LVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPE 2510
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIG--SASSSARLI 533
++W KDG+PL++ + + L I G+Y+C A++P G S S S +
Sbjct: 2511 ITWHKDGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVF 2568
Query: 534 LTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
++ D V ++ C P + W KD + S N +I L
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI--LP 2626
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK-------KLSET 872
L IL + + G+Y+C A NE G+ ++ + IPP K +
Sbjct: 2627 GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKV---YIPPIINKGDLWGPGLSPKE 2683
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAG 1052
V+ N+ LE S++WYK+ + ++ + N LQ+K+A + D G
Sbjct: 2684 VKIKVNNTLTLECEAYAIPSASLSWYKDGQPL--KSDDHVNIAANGHTLQIKEAQISDTG 2741
Query: 1053 LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPV-----TVSEGEF--------LQL 1193
YTC SN AG + I + PP F Q L + T GE + L
Sbjct: 2742 RYTCVASNIAGEDELDFDVNI---QVPPSF-QKLWEIGNMLDTGRNGEAKDVIINNPISL 2797
Query: 1194 SCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAG 1373
C + P + W K G + SD+ G VL+ DAG Y C A N AG
Sbjct: 2798 YCETNAAPPPTLTWYKDGHPLTSSDK--VLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Query: 1374 SDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNV 1553
D+ + V P+ + V+ +A G P P
Sbjct: 2856 EDSLQYDVRVLVPPIIKGANSDL-----------PEEVTVLVNKSALIECLSSGSPAPRN 2904
Query: 1554 KWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
W K L F+ + L+I +T TD G Y CVA N G + NL V+
Sbjct: 2905 SWQKDGQPLLEDDHHKFL---SNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVH 2961
Score = 150 bits (380), Expect = 3e-36
Identities = 139/579 (24%), Positives = 224/579 (38%), Gaps = 3/579 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V +G++ L C G P + W K + T ++ N +TL ++D+G
Sbjct: 3256 VSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTG 3315
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y C A N GE L V + + V + EC +G+ P ++
Sbjct: 3316 KYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQIN 3375
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W K+G PL +I+ V + I + S Y+C A+N G + L +
Sbjct: 3376 WLKNGLPLPLSSHIRLLAAGQV--IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA- 3432
Query: 546 RNPPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
PP D + + V G S C GT +AW +D + + + +S +
Sbjct: 3433 --PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVS--THG 3488
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKLSETVEETEGNS 896
L +LK + D+G+YTC A NE G+ S L + E PP + E + N
Sbjct: 3489 MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLE---PPHINGSEEHEEISVIVNNP 3545
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
L +G + W K+ + T ++ +L++ A + D G YTC S+
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYTCLASS 3603
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
AG + + P D+ +TV + L C P I WL+ G +
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDEP-RDITVLRNRQVTLECKSDAVPPPVITWLRNGERL 3662
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
+ + R +G L+ + D +Y C ASN+AG T + +T
Sbjct: 3663 QATPRVRI--LSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILT------------ 3708
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
V+ PQS+ ++ + G P P + W K R I +
Sbjct: 3709 ---VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILEN 3765
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
G L I+ TD+G Y C+A N G ++LQV+
Sbjct: 3766 G---FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH 3801
Score = 150 bits (378), Expect = 5e-36
Identities = 146/567 (25%), Positives = 220/567 (38%), Gaps = 2/567 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V + + L C+ GTP ++W K + + + H L ++ D+G Y
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINVNTSG--RNHAVLPSGGLQISRAVREDAGTY 4056
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
+C A+N G L VQ +PP S L++ V P+ C G P ++W
Sbjct: 4057 MCVAQNPAGTALGKIKLNVQ---VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWH 4113
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDGR + + +I+ L + +L I AG Y+C A N GS+S+S +L +
Sbjct: 4114 KDGRAIVE--SIRQRVLSS-GSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV---HV 4167
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRS-GGNYQISYLENSAHL 728
PP A C G + W KDN + + G Y E L
Sbjct: 4168 PPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYT---AEPYGEL 4224
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
+ V D+G YTC A N G+D+ T L + + P+FT +L V +G RL
Sbjct: 4225 ILENVVLEDSGFYTCVANNAAGEDTHTVSLTVH---VLPTFT-ELPGDVSLNKGEQLRLS 4280
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+ G + W NN I P N L +++ S D+G Y C N G
Sbjct: 4281 CKATGIPLPKLTWTFNN-NIIP---AHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGF 4336
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSE-GEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
+ +KE PPVF + G L+C V+G IQW + G +I+ S
Sbjct: 4337 VKAIGFVYVKE---PPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
R NG+ L DAGDY C A+N AG +T
Sbjct: 4394 HRIR-QLGNGS--LAIYGTVNEDAGDYTCVATNEAGVVERSMSLT--------------- 4435
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
+ EP + + G+P P + W++ + ++ R+ +
Sbjct: 4436 LQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSR-QGHSISWDDRVNVLSNN-- 4492
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEI 1706
L I D K D+ + CVA N G +
Sbjct: 4493 -SLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 147 bits (371), Expect = 4e-35
Identities = 157/623 (25%), Positives = 255/623 (40%), Gaps = 18/623 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT G+ A L C + + ++W + D +R ++ N++ L V ND+G
Sbjct: 529 VTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAG 587
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY C + G ++S FLTVQE PP + ++ T G V C+ +G ++
Sbjct: 588 EYHCMVSSEGGSSAASVFLTVQE---PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA 644
Query: 366 WFKDG---------RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASS 518
W + R DG T F+ N A + AG Y C A+N G+
Sbjct: 645 WTVNDMFIVGSHRYRMTSDG----TLFIKNAAPKD--------AGIYGCLASNSAGTDKQ 692
Query: 519 SARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQ 698
++ L E P + + + +G+ EC +G P +V W K + E+R
Sbjct: 693 NSTLRYIEA---PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPS---- 745
Query: 699 ISYLENSAHLTILKVDKG---DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE 869
++L L +LK+ + D G YTC A+NE G+ + L++ PP F ++ ++
Sbjct: 746 -TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS---PPVFIQEPAD 801
Query: 870 TVEETEGNSFRLEGRVAGSQPISVAWYK-NNVEI--HPTANCEIT-FKNNALLLQVKKAS 1037
E G++ L V G ++ W + +N+ I P + I+ + AL + AS
Sbjct: 802 VSMEI-GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWAS 860
Query: 1038 MGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSE 1217
D G Y C+ N G +++ + P+ + V EG+ L L C +
Sbjct: 861 --DKGTYICEAENQFGKIQSETTVTV-TGLVAPLIGISPSVANVIEGQQLTLPCTLLAGN 917
Query: 1218 PI-RIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSK 1394
PI +W+K + + + L + V D G+Y C ASNVAG++ +
Sbjct: 918 PIPERRWIKNSAMLLQN---PYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTS 974
Query: 1395 VTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKW 1574
V Q + +E T K G+P P+V W+K K
Sbjct: 975 VVVHVLPTIQHG---------------QQILSTIEGIPVTLPCKASGNPKPSVIWSK-KG 1018
Query: 1575 RQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEK 1754
++ F G + L + +SG Y C A N G + V L V R +
Sbjct: 1019 ELISTSSAKF--SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVR---PR 1073
Query: 1755 IEGDLRAMLKKTPV-LKKGAGEE 1820
+ GD R + + PV + AGEE
Sbjct: 1074 VFGDQRGLSQDKPVEISVLAGEE 1096
Score = 143 bits (361), Expect = 5e-34
Identities = 139/577 (24%), Positives = 226/577 (39%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENS 212
+L+C+ P ++W + +L+ AT ++ + L N D D+ Y C A N
Sbjct: 3640 TLECKSDAVPPPVITWLRNGERLQ--ATPRVRILSGGRYLQINNADLGDTANYTCVASNI 3697
Query: 213 VGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLK 392
G+ + LTV +PP+ + + + V EC G ++W KDG L
Sbjct: 3698 AGKTTREFILTVN---VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLA 3754
Query: 393 DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIP 572
G + + S L+N L+I + G+Y C ATN +A + R I + PP
Sbjct: 3755 -GNHARYSILEN-GFLHIQSAHVTDTGRYLCMATN---AAGTDRRRIDLQVHVPPSIAPG 3809
Query: 573 LAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKG 752
+ +V C TG + W K+ + N L +S L I+
Sbjct: 3810 PTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVD 3869
Query: 753 DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQP 932
DT Y C N G D T L ++ +PPS + ++ + T+ + +G
Sbjct: 3870 DTATYECTVTNGAGDDKRTVDLTVQ---VPPSIADEPTDFL-VTKHAPAVITCTASGVPF 3925
Query: 933 ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIV 1112
S+ W KN + + P + + A +++ + AG YTC N AGSA ++
Sbjct: 3926 PSIHWTKNGIRLLPRGDGYRILSSGA--IEILATQLNHAGRYTCVARNAAGSAHRHVTLH 3983
Query: 1113 IKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFAN 1292
+ E PPV + + V + L C G+ I W K G + S R +
Sbjct: 3984 VHE---PPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPS 4040
Query: 1293 GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVS 1472
G L+ + DAG Y+C A N AG+ K K+ K + ++
Sbjct: 4041 GG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHL-------KEYVIA 4091
Query: 1473 EPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTT 1652
+ I T + G P P++ W K R + + R + G L+I
Sbjct: 4092 VDKPI--------TLSCEADGLPPPDITWHK-DGRAIVESIRQRVLSSG---SLQIAFVQ 4139
Query: 1653 KTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEG 1763
D+G Y C+A N G ++ L V+ + EG
Sbjct: 4140 PGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG 4176
Score = 135 bits (340), Expect = 1e-31
Identities = 141/586 (24%), Positives = 225/586 (38%), Gaps = 13/586 (2%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G+ SL C+ +G P + W K + + + ++ + L + + +D+ Y
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALY 2267
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A N G L V + + ++ T G + EC V G P +V+W
Sbjct: 2268 SCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWM 2327
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL------- 530
KDG PL ++ LD L + S G+Y C A N G L
Sbjct: 2328 KDGHPLIKAKGVE--ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPS 2385
Query: 531 ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
I+ R+P + V S C +G + W KD + + +I L
Sbjct: 2386 IIGNHRSP-------ENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI--L 2436
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKLSETVEETE 887
L +++ D GQYTC N G++ L++ L+PP + E V+ E
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSV---LVPPHIVGENTLEDVKVKE 2493
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
S L V G+ + W+K+ + I + LQ+ + G YTC
Sbjct: 2494 KQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII--SGGRFLQITNVQVPHTGRYTCL 2551
Query: 1068 VSNDAGSALCTSSI-VIKEPKKPPV-FDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLK 1241
S+ AG + S+ V P V D + VTV L C P I W K
Sbjct: 2552 ASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFK 2611
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
G ++ S+R + G L+ + + +AG Y C A+N AG +V
Sbjct: 2612 DGTPLE-SNR-NIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPII 2669
Query: 1422 XXXXXXXXVDGKLFFVS-EPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR 1598
G L+ P+ +++ T T + P ++ W K + L
Sbjct: 2670 N--------KGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK-DGQPLKSDDH 2720
Query: 1599 IFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG--EIESNVNLQV 1730
+ I G L+I++ +D+G Y CVA N G E++ +VN+QV
Sbjct: 2721 VNIAANGH--TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQV 2764
Score = 132 bits (332), Expect = 1e-30
Identities = 137/529 (25%), Positives = 218/529 (41%), Gaps = 5/529 (0%)
Frame = +3
Query: 162 QVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVS 341
+V +D G Y C A +S G + TF V E PP + +V T G V C +
Sbjct: 488 KVTLSDEGFYECIAVSSAGTGRAQTFFDVSE---PPPVIQVPNNVTVTPGERAVLTCLII 544
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
+ +++W ++ R ++ + L N+ +L + + AG+Y C ++ GS+++S
Sbjct: 545 SAVDYNLTWQRNDRDVRLAEPARIRTLANL-SLELKSVKFNDAGEYHCMVSSEGGSSAAS 603
Query: 522 ARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
L + E PP + G C TG K+AW ++ I Y++
Sbjct: 604 VFLTVQE---PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM 660
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
+ + L I D G Y C A N G D + L E P SE +
Sbjct: 661 T---SDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE---APKLMVVQSELLVA 714
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
G+ +E + +G P V W+K ++E+ P+ + LL++++ DAG YT
Sbjct: 715 L-GDITVMECKTSGIPPPQVKWFKGDLELRPST--FLIIDPLLGLLKIQETQDLDAGDYT 771
Query: 1062 CKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLK 1241
C N+AG A T I + + PPVF Q V++ G + L C+V+G I+W +
Sbjct: 772 CVAINEAGRA--TGKITL-DVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRR 828
Query: 1242 AGREIKPSDRCSFSFAN----GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXX 1409
+ P FS ++ T L ++ +D G Y+C+A N G S++ VT
Sbjct: 829 L--DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVT--- 883
Query: 1410 XXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATF-IAKVGGDPIPNVKWTKGKWRQLN 1586
+ L +S P V+E T + G+PIP +W K L
Sbjct: 884 ---------VTGLVAPLIGIS-PSVANVIEGQQLTLPCTLLAGNPIPERRWIKNS-AMLL 932
Query: 1587 QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
Q I + G L I D G Y CVA N G ++ V+
Sbjct: 933 QNPYITVRSDG---SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH 978
Score = 98.6 bits (244), Expect = 2e-20
Identities = 94/344 (27%), Positives = 141/344 (40%), Gaps = 2/344 (0%)
Frame = +3
Query: 705 YLENSA--HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE 878
YL+ SA +L I KV D G Y C AV+ G ++ E PP + + V
Sbjct: 475 YLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE---PPPVIQ-VPNNVT 530
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
T G L + + ++ W +N+ ++ I N L L++K DAG Y
Sbjct: 531 VTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLELKSVKFNDAGEY 589
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWL 1238
C VS++ GS+ + + ++EP K V ++ + + G + + C G +I W
Sbjct: 590 HCMVSSEGGSSAASVFLTVQEPPKVTVMPKN---QSFTGGSEVSIMCSATGYPKPKIAWT 646
Query: 1239 KAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXX 1418
I S R + ++GT L K+ DAG Y C ASN AG+D S +
Sbjct: 647 VNDMFIVGSHRYRMT-SDGT--LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP- 702
Query: 1419 XXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR 1598
KL V + + + T K G P P VKW KG L
Sbjct: 703 ------------KLMVVQSELLVALGDITVME--CKTSGIPPPQVKWFKG---DLELRPS 745
Query: 1599 IFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
F+ L+I++T D+G Y CVA N+ G + L V
Sbjct: 746 TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDV 789
Score = 94.4 bits (233), Expect = 4e-19
Identities = 79/268 (29%), Positives = 120/268 (44%), Gaps = 5/268 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFR--NNVATLVFNQVDSND 179
V + G+ L C+ G P ++W + + HF N + LV +V D
Sbjct: 4269 VSLNKGEQLRLSCKATGIPLPKLTWTFNNNII------PAHFDSVNGHSELVIERVSKED 4322
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQL-RDVQETVGLPVVFECAVSGSEPI 356
SG Y+C AENSVG V + F+ V+E PP F + E +G + C V G
Sbjct: 4323 SGTYVCTAENSVGFVKAIGFVYVKE---PPVFKGDYPSNWIEPLGGNAILNCEVKGDPTP 4379
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
++ W + G ++ I+ L N +L I+ T AG Y+C ATN G S L L
Sbjct: 4380 TIQWNRKGVDIEISHRIRQ--LGN-GSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTL 4436
Query: 537 TEGRNPPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
++PP I L PV+ V+ G C TG + W++ I + +++ L
Sbjct: 4437 ---QSPPI--ITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSI--SWDDRVNVL 4489
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVG 794
N++ L I K DT ++ C A N +G
Sbjct: 4490 SNNS-LYIADAQKEDTSEFECVARNLMG 4516
>ref|XP_001726994.1| PREDICTED: LOW QUALITY PROTEIN: hemicentin-2 [Homo sapiens].
Length = 3783
Score = 167 bits (423), Expect = 3e-41
Identities = 155/592 (26%), Positives = 225/592 (38%), Gaps = 7/592 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + SLQC G P +SW + P+ ++ + L + + D+
Sbjct: 1573 VTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSP--RLQVLEDGQVLQVSTAEVADAA 1630
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y+C AEN G S+ T++ Q P L V + V C V V+
Sbjct: 1631 SYMCVAENQAG--SAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVT 1688
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+KD + L G + L TL + + S +G Y+C A N G +L +
Sbjct: 1689 WYKDSQALSLGEEV--FLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVP 1746
Query: 546 RNPPFFDIPLAPVDAV---VGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
P F P P DAV VG+ A C V W KD + + Q L
Sbjct: 1747 --PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQA--LRG 1802
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
L I + D G Y+C N G+ T L ++ +PP+F +ETV + G+
Sbjct: 1803 GQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ---VPPTFENPKTETVSQVAGSP 1859
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
L V+G +V W K+ + + +A + + L Q+ + AG YTC N
Sbjct: 1860 LVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRL--QLSRLQPAQAGTYTCVAEN 1917
Query: 1077 DAGSA---LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
A + +V + V +H V EG+ ++L C G P + WLK G
Sbjct: 1918 TQAEARKDFVVAVLVAPRIRSSGVAREH----HVLEGQEVRLDCEADGQPPPDVAWLKDG 1973
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
+ F L K + +DAG Y C A N AG D V
Sbjct: 1974 SPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQ 2033
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQLNQGGRIF 1604
DG VS P + T + V G P +V W K G L+Q R
Sbjct: 2034 G-----ADGSGTLVSRPGEL-------VTMVCPVRGSPPIHVSWLKDGLPLPLSQ--RTL 2079
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIE 1760
+H G L I D+G++ CVA + G + N LQV E +E
Sbjct: 2080 LHGSGHT--LRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVE 2129
Score = 162 bits (410), Expect = 1e-39
Identities = 161/590 (27%), Positives = 229/590 (38%), Gaps = 13/590 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V + S SL C + P V+WYK L + ++ TL + +DSG
Sbjct: 1665 VTAILNSSVSLPCDVHAHPNPEVTWYKDSQAL--SLGEEVFLLPGTHTLQLGRARLSDSG 1722
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV----GLPVVFECAVSGSEP 353
Y C A N+ G L+V +PP+F + R Q+ V G V C
Sbjct: 1723 MYTCEALNAAGRDQKLVQLSVL---VPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPE 1779
Query: 354 ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
+V+W+KDG+PL Q L L I + S G YSC +N G A + L
Sbjct: 1780 PTVTWYKDGQPLVLAQRTQA--LRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLT 1837
Query: 534 LTEGRNPPFFDIPLAP-VDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
+ + PP F+ P V V G C V+G V W KD + S + + +
Sbjct: 1838 V---QVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGV--V 1892
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVN---EVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
L + ++ G YTC A N E KD A L + P + ++
Sbjct: 1893 SRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVL-----VAPRIRSSGVAREHHV 1947
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
EG RL+ G P VAW K+ + + F + L +K DAG YT
Sbjct: 1948 LEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYT 2007
Query: 1062 CKVSNDAG--SALCTSSIVIKEPKKPPVFDQHLT---PVTVSEGEFLQLSCHVRGSEPIR 1226
C N AG + L T ++++ PP Q + GE + + C VRGS PI
Sbjct: 2008 CVAHNPAGEDARLHTVNVLV-----PPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIH 2062
Query: 1227 IQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXX 1406
+ WLK G + S R + T L V ADAG + C A++ AG +
Sbjct: 2063 VSWLKDGLPLPLSQRTLLHGSGHT--LRISKVQLADAGIFTCVAASPAGVADRNFTLQVQ 2120
Query: 1407 XXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLN 1586
V L V + VV + + G P+P V W K L+
Sbjct: 2121 -------------VPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLS 2167
Query: 1587 QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
Q ++G +LE DSG Y CVA ++ GE + L V E
Sbjct: 2168 QS-----LEQGPSLQLEA--VGAGDSGTYSCVAVSEAGEARRHFQLTVME 2210
Score = 162 bits (410), Expect = 1e-39
Identities = 145/581 (24%), Positives = 233/581 (40%), Gaps = 6/581 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V VGD A L C+ PE V+WYK L + L + +D G
Sbjct: 1760 VLVRVGDKAVLSCETDALPEPTVTWYKDGQPL--VLAQRTQALRGGQRLEIQEAQVSDKG 1817
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSR-QLRDVQETVGLPVVFECAVSGSEPISV 362
Y C+ N GE + LTVQ +PP+F + V + G P+V C VSG +V
Sbjct: 1818 LYSCKVSNVAGEAVRTFTLTVQ---VPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTV 1874
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD P++ + + L + + + AG Y+C A N A + ++
Sbjct: 1875 TWLKDRMPVES--SAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENT--QAEARKDFVVAV 1930
Query: 543 GRNPPFFDIPLAPVDAVV-GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
P +A V+ G+ +C G P VAW KD + + + +
Sbjct: 1931 LVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDG 1990
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKL--SETVEETEGN 893
L + + D G YTC A N G+D A+L+ L+PP+ + S T+ G
Sbjct: 1991 GSLVLKGLRASDAGAYTCVAHNPAGED---ARLHTVNVLVPPTIKQGADGSGTLVSRPGE 2047
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
+ V GS PI V+W K+ + + + + L++ K + DAG++TC +
Sbjct: 2048 LVTMVCPVRGSPPIHVSWLKDGLPL--PLSQRTLLHGSGHTLRISKVQLADAGIFTCVAA 2105
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFD--QHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
+ AG A ++ + + PPV + + V V G ++L C RG + W+K G
Sbjct: 2106 SPAGVADRNFTLQV---QVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDG 2162
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
+ S S G + L+ + V D+G Y C A + AG ++T
Sbjct: 2163 EPL-----LSQSLEQGPS-LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIED 2216
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
+P + + + G P PN+ W K G +
Sbjct: 2217 S-------------GQPTELSLTPGAPMELLCDAQGTPQPNITWHK-------DGQALTR 2256
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ A +R D+GLY C+A + G IE + ++V
Sbjct: 2257 LENNSRATRVLR---VRDAGLYTCLAESPAGAIEKSFRVRV 2294
Score = 159 bits (401), Expect = 1e-38
Identities = 140/530 (26%), Positives = 207/530 (39%), Gaps = 3/530 (0%)
Frame = +3
Query: 150 LVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFE 329
L +VD D G Y C A N GE L V +PP+ + V E
Sbjct: 568 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVL---VPPNIEPGPVNKAVLENASVTLE 624
Query: 330 CAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGS 509
C SG P VSWFK +P+ + S V L I Q S AG Y C A+N GS
Sbjct: 625 CLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRV--LRIEQAQLSDAGSYRCVASNVAGS 682
Query: 510 ASSSARLILTEGRNPPFFDIPLA-PVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSG 686
L + PP +P + P +V C+ TG + W KD +
Sbjct: 683 TELRYGLRVNV---PPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPA 739
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKL 863
G + LT+ D+G+Y+C AV+ VG+D L + +PPS ++L
Sbjct: 740 GTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVH---MPPSILGEEL 796
Query: 864 SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMG 1043
+ +V E S LE + P ++W+K+ + P ++ + LLQV +A +
Sbjct: 797 NVSVVANE--SVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLS--ADKALLQVDRADVW 852
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
DAG YTC+ N AG + ++ + P+ + H +TV EG +LSC RG
Sbjct: 853 DAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESH--TLTVREGHPTRLSCECRGVPFP 910
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTA-VLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
+I W K G+ + P + + +L A G Y C+ SNV G+ + ++
Sbjct: 911 KISWRKDGQPL-PGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLE 969
Query: 1401 XXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQ 1580
P + VV+ AT G P P V W +
Sbjct: 970 VHVPPQIAGPR------------EPPTQVSVVQDGVATLECNATGKPPPTVTWERD---G 1014
Query: 1581 LNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
G + + + L + +G Y CVA N G E L V
Sbjct: 1015 QPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSV 1064
Score = 157 bits (397), Expect = 3e-38
Identities = 130/500 (26%), Positives = 208/500 (41%), Gaps = 11/500 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQV------ 167
V+ + L C+ +G P ++W K NVAT V QV
Sbjct: 2675 VRAVAEEEVLLPCEASGIPRPTITWQKEGL--------------NVATGVSTQVLPGGQL 2720
Query: 168 -----DSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFEC 332
D+G Y+C A+NS G T L VQ +PP L D+ T G C
Sbjct: 2721 RIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ---VPPVIENGLPDLSTTEGSHAFLPC 2777
Query: 333 AVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSA 512
GS +++W KDG+P+ T + L + + AG Y+CTA N +G A
Sbjct: 2778 KARGSPEPNITWDKDGQPVSGAEGKFT--IQPSGELLVKNLEGQDAGTYTCTAENAVGRA 2835
Query: 513 SSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
R+ LT P F +P +G+ C G+ ++ W ++R + G
Sbjct: 2836 RR--RVHLTILVLPVFTTLP-GDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG-- 2890
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET 872
+S + + L V + D+G Y C+A N VG+ + +++KE P +
Sbjct: 2891 --VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEA---PVLQGEAFSY 2945
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAG 1052
+ E G S +L+ V G + W K+ + P + + L +++ DAG
Sbjct: 2946 LVEPVGGSIQLDCVVRGDPVPDIHWIKDGL---PLRGSHLRHQLQNGSLTIRRTERDDAG 3002
Query: 1053 LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQ 1232
Y C N+ G A +VI + PVF +TV G+ + L C G I+
Sbjct: 3003 RYQCLAENEMGVA---KKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIE 3059
Query: 1233 WLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXX 1412
WL+AG+ ++ S R + +G+ LE +V DAG Y C A N+ GS T+++ +
Sbjct: 3060 WLQAGQPLRASRRLR-TLPDGSLWLE--NVETGDAGTYDCVAHNLLGSATARAFLVVRGE 3116
Query: 1413 XXXXXXXXXXXVDGKLFFVS 1472
++G+ F V+
Sbjct: 3117 PQGSWGSMTGVINGRKFGVA 3136
Score = 156 bits (394), Expect = 8e-38
Identities = 155/612 (25%), Positives = 242/612 (39%), Gaps = 46/612 (7%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTA-TYKMHFRNNVATLVFNQVDSNDSGEYICRAEN 209
+L C+ G P + W++G+ + P TY + L Q DSG Y C A N
Sbjct: 1089 TLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLA---GGWMLKMTQTQEQDSGLYSCLASN 1145
Query: 210 SVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV----GLPVVFECAVSGSEPISVSWFKD 377
GE + + V +PPS + D++E + G C V+G ++WFKD
Sbjct: 1146 EAGEARRNFSVEVL---VPPSIENE--DLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKD 1200
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
GRPL G S + L + Q + S AG YSC A N +G + +L
Sbjct: 1201 GRPLARGDAHHIS--PDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQL--------- 1249
Query: 558 FFDIPLAPVDAVVG---ESADFECHVTGTQPIK------------VAWAKDNREIRSGGN 692
+ LAP ++G +SAD E VT PI + W KD + N
Sbjct: 1250 --SVLLAPT--ILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRN 1305
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK--KLS 866
Q+ L + L IL K D GQYTC NE+G+ + + LIPPS +K L+
Sbjct: 1306 IQL--LPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEV---LIPPSISKDDPLA 1360
Query: 867 ET----VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKA 1034
E V+ ++ LE P ++ WYK+ + P++ ++ LLQ++
Sbjct: 1361 EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVL--GEGRLLQIQPT 1418
Query: 1035 SMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVF----------------DQHLTPVT 1166
+ D+G Y C +N AG +++I + PP+F ++ VT
Sbjct: 1419 QVSDSGRYLCVATNVAGEDDQDFNVLI---QVPPMFQKVGDFSAAFEILSREEEARGGVT 1475
Query: 1167 ----VSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKAD 1334
+ E L C P + W + + + D S G VL+ V +
Sbjct: 1476 EYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGD--EVSVLQGGRVLQIPLVRAEN 1533
Query: 1335 AGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTAT 1514
AG Y CKASN G D ++ + + V +T +
Sbjct: 1534 AGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELV-----------EEVTVNASSTVS 1582
Query: 1515 FIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNK 1694
G+P+P + W + + R+ + + G L++ D+ Y CVA N+
Sbjct: 1583 LQCPALGNPVPTISWLQ-NGLPFSPSPRLQVLEDGQ--VLQVSTAEVADAASYMCVAENQ 1639
Query: 1695 HGEIESNVNLQV 1730
G E L+V
Sbjct: 1640 AGSAEKLFTLRV 1651
Score = 155 bits (393), Expect = 1e-37
Identities = 143/582 (24%), Positives = 228/582 (39%), Gaps = 6/582 (1%)
Frame = +3
Query: 3 PVKVTVGDSAS--LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSN 176
PV V ++AS L+C +G P VSW+KG + + V L Q +
Sbjct: 610 PVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRV--LRIEQAQLS 667
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQ---EQKLPPSFSRQLRDVQETVGLPVVFECAVSGS 347
D+G Y C A N G L V LPPS + V PV C +G+
Sbjct: 668 DAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPV-----LVNTPVRLTCNATGA 722
Query: 348 EPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSAR 527
++ W KDG P+ L + S +G+YSC A + +G
Sbjct: 723 PSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQD-- 780
Query: 528 LILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISY 707
++ + PP V V ES EC P ++W KD R + +S
Sbjct: 781 -VVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLS- 838
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
+ A L + + D D G YTC A+N+ G LN+ + P F + S T+ E
Sbjct: 839 -ADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNV---WVAPVFPLRESHTLTVRE 894
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
G+ RL G ++W K+ + LL + +A + G YTC+
Sbjct: 895 GHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCE 954
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
SN G++ + + P + + T V+V + L C+ G P + W + G
Sbjct: 955 CSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDG 1014
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
+ + N L + A G Y C A N+AG K +++
Sbjct: 1015 QPV--GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELS--------- 1063
Query: 1428 XXXXXXVDGKLFFVSEP-QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIF 1604
V +L +P +I + T + + G P P ++W +G+ ++ G +
Sbjct: 1064 ----VLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGE-EPVSPGEDTY 1118
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ G L++ T + DSGLY C+A N+ GE N +++V
Sbjct: 1119 LLAGG--WMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEV 1158
Score = 154 bits (389), Expect = 3e-37
Identities = 147/580 (25%), Positives = 220/580 (37%), Gaps = 4/580 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P V V L C G P + W K + P T + L ++DS
Sbjct: 704 PGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDS 763
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y C A ++VGE L V +PPS + +V V EC P +
Sbjct: 764 GRYSCVAVSAVGEDRQDVVLQVH---MPPSILGEELNVSVVANESVALECQSHAMPPPVL 820
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SW+KDGRPL+ P + S + A L + + D AG Y+C A N G + L +
Sbjct: 821 SWWKDGRPLEPRPGVHLS--ADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWV 878
Query: 543 GRNPPFFDIPLAPVDAV-VGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
P F + + V G C G K++W KD + + G + ++
Sbjct: 879 A---PVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPL-PGEGAGLQHVSAV 934
Query: 720 AHLTIL-KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT--KKLSETVEETEG 890
L L + G YTC N VG S QL + +PP ++ V +
Sbjct: 935 GRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVH---VPPQIAGPREPPTQVSVVQD 991
Query: 891 NSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
LE G P +V W ++ + A + +N L V++A G Y+C
Sbjct: 992 GVATLECNATGKPPPTVTWERDGQPV--GAELGLQLQNQGQSLHVERAQAAHTGRYSCVA 1049
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
N AG A + + P + LT +T + L L C G P I+W +
Sbjct: 1050 ENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEE 1109
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
+ P + ++ A G +L+ + D+G Y C ASN AG V
Sbjct: 1110 PVSPGED-TYLLAGGW-MLKMTQTQEQDSGLYSCLASNEAGEARRNFSV----------- 1156
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
V + + I+V++ TA + V G P P + W K R L +G H
Sbjct: 1157 --EVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFK-DGRPLARGDA--HH 1211
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
D L++ + +G Y C+A N GE + L V
Sbjct: 1212 ISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV 1251
Score = 151 bits (382), Expect = 2e-36
Identities = 145/573 (25%), Positives = 236/573 (41%), Gaps = 8/573 (1%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
++ + A L C P ++WY+ D L +A ++ L V + ++G
Sbjct: 1479 EIVENNPAYLYCDTNAIPPPDLTWYREDQPL--SAGDEVSVLQGGRVLQIPLVRAENAGR 1536
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQL-RDVQETVGLPVVFECAVSGSEPISVS 365
Y C+A N VGE L V + + +L +V V +C G+ ++S
Sbjct: 1537 YSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTIS 1596
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W ++G P P +Q L++ L + + + A Y C A N GSA +L
Sbjct: 1597 WLQNGLPFSPSPRLQV--LEDGQVLQVSTAEVADAASYMCVAENQAGSAE---KLFTLRV 1651
Query: 546 RNPP-FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ PP + L V A++ S C V +V W KD++ + G ++ L +
Sbjct: 1652 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGE--EVFLLPGTH 1709
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF---TKKLSETVEETEGN 893
L + + D+G YTC A+N G+D QL++ L+PP+F + + V G+
Sbjct: 1710 TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSV---LVPPAFRQAPRGPQDAVLVRVGD 1766
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
L +V WYK+ + + L++++A + D GLY+CKVS
Sbjct: 1767 KAVLSCETDALPEPTVTWYKDGQPLVLAQRTQAL--RGGQRLEIQEAQVSDKGLYSCKVS 1824
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSE--GEFLQLSCHVRGSEPIRIQWLKAG 1247
N AG A+ T ++ + + PP F+ T TVS+ G L L+C V G + WLK
Sbjct: 1825 NVAGEAVRTFTLTV---QVPPTFENPKTE-TVSQVAGSPLVLTCDVSGVPAPTVTWLKDR 1880
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
++ S G L+ + A AG Y C A N ++ K V
Sbjct: 1881 MPVESSAVHGVVSRGGR--LQLSRLQPAQAGTYTCVAENTQ-AEARKDFVV--------- 1928
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQLNQGGRIF 1604
V ++ + V+E + G P P+V W K G + G +
Sbjct: 1929 ---AVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLR 1985
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
+ G L ++ +D+G Y CVA N GE
Sbjct: 1986 FYLDG--GSLVLKGLRASDAGAYTCVAHNPAGE 2016
Score = 150 bits (379), Expect = 4e-36
Identities = 155/625 (24%), Positives = 241/625 (38%), Gaps = 19/625 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G L C+ G P +SW K L H L Q G Y
Sbjct: 892 VREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTY 951
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFS------RQLRDVQETVGLPVVFECAVSGSEP 353
C N VG S L V +PP + Q+ VQ+ V EC +G P
Sbjct: 952 TCECSNVVGNSSQDLQLEVH---VPPQIAGPREPPTQVSVVQDGVA---TLECNATGKPP 1005
Query: 354 ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
+V+W +DG+P+ G + + +L++ + + G+YSC A N G A L
Sbjct: 1006 PTVTWERDGQPV--GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELS 1063
Query: 534 LTEGRNPPFF--DI-PLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
+ PP D+ PL + A + C G P + W + + G + +
Sbjct: 1064 VLV---PPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYL- 1119
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIK-ERLIPPSFTKK-LSETVE 878
L L + + + D+G Y+C A NE G+ A+ N E L+PPS + L E ++
Sbjct: 1120 -LAGGWMLKMTQTQEQDSGLYSCLASNEAGE----ARRNFSVEVLVPPSIENEDLEEVIK 1174
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEIT-FKNNALLLQVKKASMGDAGL 1055
+G + L V G + W+K+ P A + + +LLQV +A++ AG
Sbjct: 1175 VLDGQTAHLMCNVTGHPQPKLTWFKDG---RPLARGDAHHISPDGVLLQVLQANLSSAGH 1231
Query: 1056 YTCKVSNDAGSALCTSSIVIKEPKKPPVF----DQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
Y+C +N G T + P + D VTV+ + L C
Sbjct: 1232 YSCIAANAVGEK--TKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSP 1289
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTX 1403
I W+K G + S + GT L+ + K DAG Y C +N G V
Sbjct: 1290 NITWMKDGAPFEASR--NIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEV 1347
Query: 1404 XXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQL 1583
V K ++ +T T + P P ++W K + +
Sbjct: 1348 LIPPSISKDDPLAEVGVK--------EVKTKVNSTLTLECESWAVPPPTIRWYKDG-QPV 1398
Query: 1584 NQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEG 1763
R+ + G+ L+I+ T +DSG Y CVA N GE + + N+ + +K+ G
Sbjct: 1399 TPSSRLQV--LGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKV-G 1455
Query: 1764 DLRA---MLKKTPVLKKGAGEEEEI 1829
D A +L + + G E EI
Sbjct: 1456 DFSAAFEILSREEEARGGVTEYREI 1480
Score = 147 bits (370), Expect = 5e-35
Identities = 145/609 (23%), Positives = 235/609 (38%), Gaps = 34/609 (5%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VTV + SL C+ P ++W K A+ + L D+G
Sbjct: 1269 VTVTVNNPISLICEALAFPSPNITWMKDGAPFE--ASRNIQLLPGTHGLQILNAQKEDAG 1326
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQ-------LRDVQETVGLPVVFECAVSG 344
+Y C N +GE + + V +PPS S+ +++V+ V + EC
Sbjct: 1327 QYTCVVTNELGEAVKNYHVEVL---IPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWA 1383
Query: 345 SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
P ++ W+KDG+P+ +Q L L I T S +G+Y C ATN G
Sbjct: 1384 VPPPTIRWYKDGQPVTPSSRLQV--LGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDF 1441
Query: 525 RLILTEGRNPPFF----------DIPLAPVDA----------VVGESADFECHVTGTQPI 644
+++ + PP F +I +A V A C P
Sbjct: 1442 NVLI---QVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPP 1498
Query: 645 KVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI 824
+ W ++++ + +G ++S L+ L I V + G+Y+C A NEVG+D +L +
Sbjct: 1499 DLTWYREDQPLSAGD--EVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLV 1556
Query: 825 KERLIPPSFTKKLSETVEETEGNS---FRLEGRVAGSQPISVAWYKNNVEIHPTANCEIT 995
L PP E VEE N+ L+ G+ +++W +N + P+ ++
Sbjct: 1557 ---LTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVL 1613
Query: 996 FKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSE 1175
+ +LQV A + DA Y C N AGSA ++ ++ P P + L VT
Sbjct: 1614 --EDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVP--PRIAGLDLEQVTAIL 1669
Query: 1176 GEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCK 1355
+ L C V + W K + + + GT L+ +D+G Y C+
Sbjct: 1670 NSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFL--LPGTHTLQLGRARLSDSGMYTCE 1727
Query: 1356 ASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGG 1535
A N AG D +++ + +RV +K A +
Sbjct: 1728 ALNAAGRDQKLVQLSVLVPPAFRQAPRGP---------QDAVLVRVGDK--AVLSCETDA 1776
Query: 1536 DPIPNVKWTKGKWRQLNQGGRIFIHQKGDE----AKLEIRDTTKTDSGLYRCVAFNKHGE 1703
GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++V +G A C++ P + W+K ++ + + V+TL + D
Sbjct: 941 PLEVALGHLAKFTCEVQIAPNVRFQWFKAGREIYESDKCSIRSSKYVSTLEILRTQVVDC 1000
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+A N G VS + LTV E PP+F + + V VG F C V G+ I
Sbjct: 1001 GEYTCKASNEYGSVSCTATLTVTEA-YPPTFYSRPKSVTTFVGKTAKFLCTVLGTPVIET 1059
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W KDG L PN + S +N +L + G YSC A+N G+ A LI+ +
Sbjct: 1060 IWQKDGAALSPSPNRKISEAENKHSLELSNLTIQDRGVYSCKASNKFGADICQAELIIID 1119
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L PV + + + EC V + + V W KD +++ G +++I + + A
Sbjct: 1120 ---KPHFIKELEPVQSAINKKIRLECQVDEDRKVTVTWNKDGQKLPPGKDHKIYFEDKIA 1176
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I D+G Y C A NE G S +A + I+E PPSF KK+ + G S R
Sbjct: 1177 SLEIPLAKLKDSGTYVCTASNEAGSSSSSATVTIRE---PPSFVKKVDPSYLMLPGESAR 1233
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L ++ GS I V W+K+N E++ + ++F N+ +L + + D+G Y+C+ ND
Sbjct: 1234 LHCKLKGSPVIQVTWFKDNKELNESNTIRMSFVNSEAVLDLTDVKVTDSGSYSCEAVNDV 1293
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GS C++ IV+KEP P F + L P + G L C + G+ P I W K ++I+
Sbjct: 1294 GSDTCSAEIVVKEP---PSFIKTLEPADIVRGTNALLQCEISGTGPFEISWFKDKKQIRS 1350
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + LE AD G+Y C +N G +
Sbjct: 1351 SKKYRLFSQKSLVSLEIFSFNSADVGEYECVVANEVGKCGCSATHLLKEPPT-------- 1402
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
FV + + T T A V G +V W KG+ L + G+I
Sbjct: 1403 -------FVKKVDDFTALAGQTVTLQAAVRGSEPISVTWMKGQ-EILKEDGKIKTSFSNG 1454
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
A L I D + Y C+A N+ G S L V E K
Sbjct: 1455 VATLIIPDVQISHGDKYTCLAENEAGSQTSVGELIVKEPAK 1495
Score = 253 bits (646), Expect = 5e-67
Identities = 176/607 (28%), Positives = 279/607 (45%), Gaps = 2/607 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSND-SGEYIC 197
GD +L + E V+WY + +K N TLV + V++ + G Y C
Sbjct: 853 GDVVNLTSSITNAKE--VNWYFEGKLVHSDEKFKCLQDQNTYTLVIHGVNTEEHQGAYTC 910
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKD 377
A N+ G S+S LTV ++ P R++ ++ +G F C V + + WFK
Sbjct: 911 EALNAKGNASTSAKLTV-VKRAAPVIKRRIEPLEVALGHLAKFTCEVQIAPNVRFQWFKA 969
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
GR + + V+TL I +T G+Y+C A+N GS S +A L +TE P
Sbjct: 970 GREIYESDKCSIRSSKYVSTLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPT 1029
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F+ P + V VG++A F C V GT I+ W KD + N +IS EN L +
Sbjct: 1030 FYSRPKS-VTTFVGKTAKFLCTVLGTPVIETIWQKDGAALSPSPNRKISEAENKHSLELS 1088
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+ D G Y+C A N+ G D C A+L I ++ P F K+L E V+ RLE +V
Sbjct: 1089 NLTIQDRGVYSCKASNKFGADICQAELIIIDK---PHFIKEL-EPVQSAINKKIRLECQV 1144
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
+ ++V W K+ ++ P + +I F++ L++ A + D+G Y C SN+AGS+
Sbjct: 1145 DEDRKVTVTWNKDGQKLPPGKDHKIYFEDKIASLEIPLAKLKDSGTYVCTASNEAGSSSS 1204
Query: 1098 TSSIVIKEPKKPPVFDQHLTP-VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRC 1274
++++ I+E PP F + + P + GE +L C ++GS I++ W K +E+ S+
Sbjct: 1205 SATVTIRE---PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKDNKELNESNTI 1261
Query: 1275 SFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDG 1454
SF N AVL+ DV D+G Y C+A N GSDT +++ V
Sbjct: 1262 RMSFVNSEAVLDLTDVKVTDSGSYSCEAVNDVGSDTCSAEIV---------------VKE 1306
Query: 1455 KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKL 1634
F+ + +V T A ++ G + W K K +Q+ + + + L
Sbjct: 1307 PPSFIKTLEPADIVRGTNALLQCEISGTGPFEISWFKDK-KQIRSSKKYRLFSQKSLVSL 1365
Query: 1635 EIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAG 1814
EI D G Y CV N+ G+ + + E K D A+ +T L+
Sbjct: 1366 EIFSFNSADVGEYECVVANEVGKCGCSATHLLKEPPTFVKKVDDFTALAGQTVTLQAAVR 1425
Query: 1815 EEEEIDI 1835
E I +
Sbjct: 1426 GSEPISV 1432
Score = 239 bits (611), Expect = 5e-63
Identities = 158/576 (27%), Positives = 261/576 (45%), Gaps = 1/576 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G + L+ G+ V W KG +L + + + ++L V ++DSG Y
Sbjct: 1694 VLPGSAVCLKSTFRGSGPFTVRWLKGGRELVSGGSCYITKEASESSLELYVVKTSDSGTY 1753
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-GLPVVFECAVSGSEPISVSW 368
C+ N+ G V S L V+E P +F +L Q G C V+G+ PI ++W
Sbjct: 1754 TCQVGNAAGSVECSANLFVKE---PATFIEKLEPSQLLKKGDSTQLACKVAGTPPIKITW 1810
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
F + R LK+G + SF+++ A L++ + +G+Y C A N GS + LI+ E
Sbjct: 1811 FANDRELKEGGRHRMSFVESTAVLSLTEVTTEDSGEYMCEAQNEAGSDHCGSILIVKES- 1869
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
P+F PV+ + V GT P + W KDN +RSG Y+ + L
Sbjct: 1870 --PYFTKEFKPVEVLKEYDVMLLAEVAGTPPFDITWFKDNTTLRSGRKYKTFIQDQLVSL 1927
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
ILK D G+Y C NEVG +C+A++ ++E PPSF KK+ E+ G + +
Sbjct: 1928 QILKFVATDAGEYQCRVTNEVGSSTCSARVTLRE---PPSFVKKI-ESTSSLRGGTAAFQ 1983
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+ GS PI+V W K+N EI N +TF+NN L + + G Y C+ NDAG
Sbjct: 1984 ATLKGSLPITVTWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGI 2043
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
C++ + +KE P + + V++G+ L G++ I +W K G+E+
Sbjct: 2044 QRCSALLSVKE---PATITEEAVSIDVTQGDPATLQVKFSGTKEITARWFKDGQELTLGQ 2100
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ S + ++L+ K D+G+Y + N G + K+ +
Sbjct: 2101 KYKISVTDTVSILKIISTEKRDSGEYTFEVQNDVGRSSCKASINVLDLIIPPS------- 2153
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F + + ++ ++ V G +++W K ++++ + + A
Sbjct: 2154 -----FTKRLKKMDSIKGSSIDLECIVAGSHPISIQWFKDD-QEISASEKYKFSFHDNTA 2207
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
LEI +DSG Y C A NK G + + +L V E
Sbjct: 2208 FLEISHLEGSDSGTYTCSATNKAGHNQCSGHLTVKE 2243
Score = 188 bits (478), Expect = 1e-47
Identities = 143/512 (27%), Positives = 225/512 (43%), Gaps = 1/512 (0%)
Frame = +3
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGR 383
E VGE + V E P L D G V +++ ++ V+W+ +G+
Sbjct: 820 EGGVGEAQEAEGSAVGEDG--PVMLTPLVDTTAEEGDVVNLTSSITNAK--EVNWYFEGK 875
Query: 384 PLKDGPNIQTSFLDNVATLNIFQTD-RSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ + N TL I + G Y+C A N G+AS+SA+L + + R P
Sbjct: 876 LVHSDEKFKCLQDQNTYTLVIHGVNTEEHQGAYTCEALNAKGNASTSAKLTVVK-RAAPV 934
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
+ P++ +G A F C V ++ W K REI I + + L IL+
Sbjct: 935 IKRRIEPLEVALGHLAKFTCEVQIAPNVRFQWFKAGREIYESDKCSIRSSKYVSTLEILR 994
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
D G+YTC A NE G SCTA L + E PP+F + ++V G + + V
Sbjct: 995 TQVVDCGEYTCKASNEYGSVSCTATLTVTE-AYPPTFYSR-PKSVTTFVGKTAKFLCTVL 1052
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+ I W K+ + P+ N +I+ N L++ ++ D G+Y+CK SN G+ +C
Sbjct: 1053 GTPVIETIWQKDGAALSPSPNRKISEAENKHSLELSNLTIQDRGVYSCKASNKFGADICQ 1112
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSF 1280
+ ++I + P F + L PV + + ++L C V + + W K G+++ P
Sbjct: 1113 AELIIID---KPHFIKELEPVQSAINKKIRLECQVDEDRKVTVTWNKDGQKLPPGKDHKI 1169
Query: 1281 SFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKL 1460
F + A LE D+G YVC ASN AGS +S + VT +
Sbjct: 1170 YFEDKIASLEIPLAKLKDSGTYVCTASNEAGSSSSSATVTIR--------------EPPS 1215
Query: 1461 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEI 1640
F S ++ +A K+ G P+ V W K ++LN+ I + EA L++
Sbjct: 1216 FVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKDN-KELNESNTIRMSFVNSEAVLDL 1274
Query: 1641 RDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
D TDSG Y C A N G + + V E
Sbjct: 1275 TDVKVTDSGSYSCEAVNDVGSDTCSAEIVVKE 1306
Score = 116 bits (291), Expect = 7e-26
Identities = 131/556 (23%), Positives = 229/556 (41%), Gaps = 34/556 (6%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV V+ G+ L C + G+ I + W K +++P+ F N A L V DS
Sbjct: 5890 PVTVSEGEFVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLELKDVAKADS 5949
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLP-PSFSRQLRD-----VQETVGLPVVFECAVS- 341
G+Y+C+A N+ G +S + +T++++ P+ + D V E + VV + +
Sbjct: 5950 GDYVCKASNAAGSDTSKSKVTIKDKPAAVPAAKKAAVDGRLFFVSEPQSIRVVEKTTATF 6009
Query: 342 ----GSEPI-SVSWFKDG-RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPI 503
G +PI +V W K R L G I + A L I T ++ +G Y C A N
Sbjct: 6010 IAKVGGDPIPNVKWTKGKWRQLNQGGRIHIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKH 6069
Query: 504 GSASSSARLILTEGRNPPFFDIPLAPV---DAVVGESADFECHVTGTQPIKVAWAKDNRE 674
G S+ L + E + + L + V+ + E + + +K K+ +
Sbjct: 6070 GEIESNVNLQVDERKKQEKIEGDLRAMLKKTPVLKKGTGEEEEIDIMELLKNVDPKEYEK 6129
Query: 675 -------------IRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQ 815
+++ + S E + L I +++K + + K+
Sbjct: 6130 YARMYGITDFRGLLQAFEMLKQSQEEETHRLEIEEIEKSEKDE----------KEFEELV 6179
Query: 816 LNIKERLI---PPSFTKKL-SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTAN 983
I++RL P + K + ++TV + + F ++ ++ + I ++WYK ++ P+
Sbjct: 6180 SFIQQRLSQTEPVTLIKDIENQTVLKDDEAVFEIDIKINYPE-IKLSWYKGTEKLEPSDK 6238
Query: 984 CEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPV 1163
EI+ + L+VK + D G Y SA T VI+ P +++HL V
Sbjct: 6239 FEISIDGDRHTLRVKDCQLKDQGNYRLVCGPHIASAKLT---VIE-----PAWERHLQDV 6290
Query: 1164 TVSEGEFLQLSCHVRGSEP-IRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAG 1340
T+ EG+ ++C S P ++ W + GR +KP R + + L DV D G
Sbjct: 6291 TLKEGQTCTMTCQF--SVPNVKSSWFRNGRLLKPQGRHQTAVEHKVHKLTIADVRAEDQG 6348
Query: 1341 DYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFI 1520
Y CK ++ S + + + F Q+I V E +ATF
Sbjct: 6349 RYTCKYEDLETSAELRIEAE------------------PIQFTKRIQNIVVSEHQSATFE 6390
Query: 1521 AKVGGDPIPNVKWTKG 1568
+V D V W KG
Sbjct: 6391 CEVSFDD-AIVTWYKG 6405
Score = 105 bits (262), Expect = 2e-22
Identities = 134/592 (22%), Positives = 226/592 (38%), Gaps = 4/592 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++V+ D+ L C+++ P V+WYKGD ++ T Y++ L+ D+G
Sbjct: 9367 IEVSETDTIKLVCEVS-KPGAEVTWYKGDEEIIETGRYEILTDGRKRILIIQNAHLEDAG 9425
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y CR SS T V+ +L F + ++++ G F C++S E V
Sbjct: 9426 NYNCRLP------SSRTDGKVKVHELAAEFISKPQNLEVLEGEKAEFVCSIS-KENFEVQ 9478
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W +D + L+ G L + G Y +G+A ++A L + E
Sbjct: 9479 WKRDDKTLEPGDKYDIIADGKKRILVVKDATLQDMGTYVVM----VGAARAAAHLTVIEK 9534
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
+PL + F C V T+ K W ++ I Y I +
Sbjct: 9535 LR---IIVPLKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVYT 9590
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKD-SCTAQLNIKE---RLIPPSFTKKLSETVEETEGN 893
L I D Y+ N G++ A L ++E R+I P K ET+E+
Sbjct: 9591 LRIRDARLDDQANYSVSLTNHRGENVKSAANLIVEEEDLRIIEP---LKDIETMEKKTVT 9647
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
+ R+ +++ W +N E+ L +K D G Y
Sbjct: 9648 FWCKVNRL----NVTLKWTRNGEEVAFDNRVTYRIDKYKHSLIIKDCGFPDEGEYVVTAG 9703
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
D A ++I+ P + F +HL TV+E + SC + E ++W + GRE
Sbjct: 9704 QDKSVA---ELLIIEAPTE---FIEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGRE 9756
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
IK + F T L KD D +Y C G + KS+
Sbjct: 9757 IKEGKKYKFEKEGSTHRLIIKDCRLDDECEYAC------GVEDRKSRARLFVE------- 9803
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
+ + + PQ I T F+A++ D + V+W + + QG + +
Sbjct: 9804 -----EIPVEIIRPPQDILEAPGTDVVFLAELNKDKV-EVQWLRNN-MVVVQGDKHQMMS 9856
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDL 1769
+G +L+I + D G YR +A +K E+ L++ K + + DL
Sbjct: 9857 EGKIHRLQICNIQPRDQGEYRFIAKDK----EARAKLELAAAPKIKTGDQDL 9904
Score = 103 bits (258), Expect = 5e-22
Identities = 139/583 (23%), Positives = 223/583 (38%), Gaps = 33/583 (5%)
Frame = +3
Query: 24 DSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRA 203
D LQC+++ + V W+K +++P+ + L+ + +D G+Y C
Sbjct: 8982 DEVILQCEISKA-DAPVKWFKDGEEIKPSKNVVIKADGKKRILILKKALKSDIGQYTC-- 9038
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGR 383
G +S L ++++++ R L V+ FE +S E I +W G
Sbjct: 9039 --DCGTDKTSGKLNIEDREI--KLVRPLHSVEVMETETARFETEIS-EEDIHANWKLKGE 9093
Query: 384 PLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSAR------------ 527
L P+ + + L + G A N SA +
Sbjct: 9094 ALLQTPDCEIKEEGKMHFLILHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKD 9153
Query: 528 LILTEGRNPPFF------DIP---------LAPVDAVVGESAD--FECHVTGTQPIKVAW 656
+ +T G F DIP L P + V E A EC V+ + KV W
Sbjct: 9154 VTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSEKTVEEEATAVLECEVS-RENAKVKW 9212
Query: 657 AKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERL 836
K+ EI Y+I L I D YTC A + K SC LN+
Sbjct: 9213 FKNGTEILKSKKYEIVADGRVRKLIIHGCTPEDIKTYTCDAKDF--KTSCN--LNV---- 9264
Query: 837 IPP--SFTKKLSET-VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNN 1007
+PP F + L++ V+E E F E + V W+K+ EI +I K
Sbjct: 9265 VPPHVEFLRPLTDLQVKEKEMARFECE---ISRENAKVQWFKDGAEIKKGKKYDIISKGA 9321
Query: 1008 ALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFL 1187
+L + K + D Y+C+V S + T V+ E VF ++L + VSE + +
Sbjct: 9322 VRILVINKCLLDDEAEYSCEVKTARTSGMLT---VLAE---EAVFTKNLGNIEVSETDTI 9375
Query: 1188 QLSCHVRGSEP-IRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASN 1364
+L C V S+P + W K EI + R +L ++ DAG+Y C+
Sbjct: 9376 KLVCEV--SKPGAEVTWYKGDEEIIETGRYEILTDGRKRILIIQNAHLEDAGNYNCRLP- 9432
Query: 1365 VAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPI 1544
S + KV F+S+PQ++ V+E A F+ + +
Sbjct: 9433 ---SSRTDGKVKVHELAAE--------------FISKPQNLEVLEGEKAEFVCSISKENF 9475
Query: 1545 PNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLY 1673
V+W + + L G + I G + L ++D T D G Y
Sbjct: 9476 -EVQWKRDD-KTLEPGDKYDIIADGKKRILVVKDATLQDMGTY 9516
Score = 103 bits (257), Expect = 6e-22
Identities = 146/580 (25%), Positives = 224/580 (38%), Gaps = 6/580 (1%)
Frame = +3
Query: 15 TVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYI 194
+VG SA +C ++ + I SW K + +R + ++ L V +D+GEY
Sbjct: 8080 SVGSSAIFECLVSPSTAI-TSWMKDGSNIRESPKHRFIADGKDRKLHIMDVQLSDAGEYT 8138
Query: 195 CRAENSVGEVSSSTFLTVQEQKLPPSFSRQL-RDVQETVGLPVVFECAVSGSEPISVSWF 371
C E +S+ L V+E LP F + L +V G P+ C ++ V W
Sbjct: 8139 CVLRLGNKEKTSTAKLVVEE--LPVRFVKTLEEEVTVVKGQPLYLSCELNKER--DVVWR 8194
Query: 372 KDGRPLKDGP-NIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
KDG+ + + P I + + L I D AG Y+ T N SS ++ R
Sbjct: 8195 KDGKIVVEKPGKIVPGVIGLLRALTINDADDQDAGTYTVTVENANNLECSSCVKVVEVIR 8254
Query: 549 N---PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
+ P D + P V F C + P + W K EI N + +
Sbjct: 8255 DWLVKPIRDQHVKPKGTAV-----FTCVIAKDTP-NIKWFKGYDEIPLEPNDKTEIVREG 8308
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE-TVEETEGNS 896
HL LKV YAV GK A+L + ER + K + + T+ E E S
Sbjct: 8309 NHL-FLKVKNATPEDIDEYAVEIEGK-RYPAKLTLGEREV--ELLKPIEDVTIYEKESAS 8364
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
F E I W + P+ CEI + L + K + AG +V
Sbjct: 8365 FDAE---ISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAG----EVLY 8417
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
A +A T+ + +KE + F L VTV E + C + + + W K I
Sbjct: 8418 QALNAFTTAILTVKEIELD--FAVPLKDVTVPERRQARFECVL--TREANVIWSKGPDII 8473
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
K SD+ +L D D G Y + S ++ VT
Sbjct: 8474 KASDKFDIIADGKKHILVINDSHFDDEGVYTAEVEGKKSS--ARLFVTGI---------- 8521
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
+L F+S + V E TATF+ ++ + + +V W K +L+ + I +
Sbjct: 8522 ------RLKFISPLEDQTVKEGQTATFVCELSHEKM-HVVWFKND-AKLHTSRTVLISSE 8573
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
G KLEIR+ T D R + ++ S NL+V E
Sbjct: 8574 GKTHKLEIREVTLDDISQIRA----QVKDLSSTANLKVLE 8609
Score = 102 bits (255), Expect = 1e-21
Identities = 138/575 (24%), Positives = 218/575 (37%), Gaps = 3/575 (0%)
Frame = +3
Query: 3 PVK-VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSND 179
P+K VTV + + + T E V W KG ++ + + + LV N +D
Sbjct: 8440 PLKDVTVPERRQARFECVLTREANVIWSKGPDIIKASDKFDIIADGKKHILVINDSHFDD 8499
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
G Y E SS L V +L F L D G F C +S E +
Sbjct: 8500 EGVYTAEVEGK----KSSARLFVTGIRL--KFISPLEDQTVKEGQTATFVCELS-HEKMH 8552
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V WFK+ L + S L I + Q + SS+A L +
Sbjct: 8553 VVWFKNDAKLHTSRTVLISSEGKTHKLEIREVTLDDISQIRA----QVKDLSSTANLKVL 8608
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E P+F + L V + +C V+ P+K W KD EI Y I
Sbjct: 8609 EA--DPYFTVKLHDKTGVEKDEIILKCEVSKDVPVK--WFKDGEEIVPSAKYSIKTDGLR 8664
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I K + D G+Y C + G D A + ++ RLI +K VE G +
Sbjct: 8665 RILKIKKAELKDKGEYMC----DCGTDQTKANVTVEARLIK---VEKPLYGVELFVGETA 8717
Query: 900 RLEGRVAGSQP-ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
R E + S+P + W + + +CEI +L + + G +VS
Sbjct: 8718 RFE--IELSEPDVHGQWKLKGEPLTASPDCEIIEDGKKHILVLYNCQLDMTG----EVSF 8771
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
A +A +++ +KE P +F L+ V V E + + C V EP +WLK +EI
Sbjct: 8772 QAANAKSAANLKVKE--LPLIFITPLSDVKVFEKDEAKFECEV-SREPKTFRWLKGTQEI 8828
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
D+ L K D G Y+ +A + TS +
Sbjct: 8829 TGDDKVELIKDGTKHSLVIKSAAFEDEGKYIFEAED---KHTSGKLI------------- 8872
Query: 1437 XXXVDG-KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
++G +L F++ + + E+ +A F ++ D I VKW K R L+ +++
Sbjct: 8873 ---IEGIRLKFLTPLKDVTAKERESAVFTVELSHDNI-RVKWFKNDQR-LHTSRSVWMDD 8927
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNV 1718
+G + RD + D+ + A E + V
Sbjct: 8928 EGKTHSITFRDLSIDDTSQIKVEAMGLSSEAKLTV 8962
Score = 99.0 bits (245), Expect = 2e-20
Identities = 138/561 (24%), Positives = 228/561 (40%), Gaps = 3/561 (0%)
Frame = +3
Query: 24 DSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRA 203
+SAS +++ G KG+ LRP+ T ++ L ++V + +GE + +A
Sbjct: 8361 ESASFDAEISEADIPGQWKLKGEL-LRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQA 8419
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGR 383
N+ ++ LTV+E +L F+ L+DV FEC ++ +V W K
Sbjct: 8420 LNAF----TTAILTVKEIEL--DFAVPLKDVTVPERRQARFECVLT--REANVIWSKGPD 8471
Query: 384 PLK--DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
+K D +I ++ +N D G Y T + SSARL +T R
Sbjct: 8472 IIKASDKFDIIADGKKHILVINDSHFDDE--GVY----TAEVEGKKSSARLFVTGIRLK- 8524
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F PL G++A F C ++ + + V W K++ ++ + IS + L I
Sbjct: 8525 -FISPLEDQTVKEGQTATFVCELSH-EKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEIR 8582
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+V D Q +V S TA L + E P FT KL + E + L+ V
Sbjct: 8583 EVTLDDISQIRA----QVKDLSSTANLKVLEA--DPYFTVKLHDKTG-VEKDEIILKCEV 8635
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
S+ + V W+K+ EI P+A I +L++KKA + D G Y C D A
Sbjct: 8636 --SKDVPVKWFKDGEEIVPSAKYSIKTDGLRRILKIKKAELKDKGEYMCDCGTDQTKANV 8693
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEP-IRIQWLKAGREIKPSDRC 1274
T + + +KP L V + GE + + SEP + QW G + S C
Sbjct: 8694 TVEARLIKVEKP------LYGVELFVGETARFEIEL--SEPDVHGQWKLKGEPLTASPDC 8745
Query: 1275 SFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDG 1454
+L + G+ +A+N + K K +
Sbjct: 8746 EIIEDGKKHILVLYNCQLDMTGEVSFQAANAKSAANLKVK------------------EL 8787
Query: 1455 KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKL 1634
L F++ ++V EK A F +V +P +W KG +++ ++ + + G + L
Sbjct: 8788 PLIFITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGT-QEITGDDKVELIKDGTKHSL 8845
Query: 1635 EIRDTTKTDSGLYRCVAFNKH 1697
I+ D G Y A +KH
Sbjct: 8846 VIKSAAFEDEGKYIFEAEDKH 8866
Score = 89.4 bits (220), Expect = 1e-17
Identities = 113/484 (23%), Positives = 187/484 (38%), Gaps = 7/484 (1%)
Frame = +3
Query: 243 TVQEQKLPPSFSRQLRDV----QETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQ 410
T Q + +P F ++++D+ E+VG +FEC VS S I+ SW KDG +++ P +
Sbjct: 8056 TYQLKAVPLKFVKEIKDIVLTEAESVGSSAIFECLVSPSTAIT-SWMKDGSNIRESPKHR 8114
Query: 411 TSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDA 590
L+I S AG+Y+C +S+A+L++ E F V
Sbjct: 8115 FIADGKDRKLHIMDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEE-LPVRFVKTLEEEVTV 8173
Query: 591 VVGESADFECHVTGTQPIKVAWAKDNR-EIRSGGNYQISYLENSAHLTILKVDKGDTGQY 767
V G+ C + + V W KD + + G + LTI D D G Y
Sbjct: 8174 VKGQPLYLSCELNKER--DVVWRKDGKIVVEKPGKIVPGVIGLLRALTINDADDQDAGTY 8231
Query: 768 TCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAW 947
T V C++ + + E +I K + + + +G + + V ++ W
Sbjct: 8232 T-VTVENANNLECSSCVKVVE-VIRDWLVKPIRDQHVKPKGTA--VFTCVIAKDTPNIKW 8287
Query: 948 YK--NNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKE 1121
+K + + + P EI + N L L+VK A+ D Y ++ A T E
Sbjct: 8288 FKGYDEIPLEPNDKTEIVREGNHLFLKVKNATPEDIDEYAVEIEGKRYPAKLTLGEREVE 8347
Query: 1122 PKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTA 1301
KP + VT+ E E + ++ I QW G ++PS C G
Sbjct: 8348 LLKP------IEDVTIYEKESASFDAEISEAD-IPGQWKLKGELLRPSPTCEIKAEGGKR 8400
Query: 1302 VLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQ 1481
L V AG+ + +A N + K + +L F +
Sbjct: 8401 FLTLHKVKLDQAGEVLYQALNAFTTAILTVK------------------EIELDFAVPLK 8442
Query: 1482 SIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTD 1661
+ V E+ A F + + NV W+KG + + I G + L I D+ D
Sbjct: 8443 DVTVPERRQARFECVLTRE--ANVIWSKGP-DIIKASDKFDIIADGKKHILVINDSHFDD 8499
Query: 1662 SGLY 1673
G+Y
Sbjct: 8500 EGVY 8503
Score = 84.0 bits (206), Expect = 5e-16
Identities = 56/200 (28%), Positives = 86/200 (43%), Gaps = 24/200 (12%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
++++GD A L + G P+ + W+ L P+A YK F N +L+ D GE
Sbjct: 63 EISIGDVAKLSVTVTGIPKPKIQWFFKGVMLTPSADYKFVFDGNDHSLIILFTKFEDEGE 122
Query: 189 YICRAENSVGEVSSS---------------------TFLTVQEQKLPPSFSRQLRDVQET 305
Y C A N G+ S TFL E PP F ++ + +
Sbjct: 123 YTCVASNEYGQAVCSASLKISSKGEGQKETEAEPVETFLEKFEGPCPPYFLKEFKPIHCA 182
Query: 306 VGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFL---DNVATLNIFQTDRSFAGQ 476
GLP VFE V G +V+WFK+ + L N+ + + D T + R +G
Sbjct: 183 RGLPAVFEYVVLGEPAPTVTWFKESKQL--CTNVYHTIIHNPDGSGTFIVNDPQREDSGL 240
Query: 477 YSCTATNPIGSASSSARLIL 536
Y C A N G ++ +A L++
Sbjct: 241 YVCRAENMWGESTCTAELLV 260
Score = 70.1 bits (170), Expect = 7e-12
Identities = 57/225 (25%), Positives = 96/225 (42%), Gaps = 22/225 (9%)
Frame = +3
Query: 210 SVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPL 389
S + S+TF + +E +P F +++ + + ++G V+G + WF G L
Sbjct: 35 SAPSIHSTTFESKKEGHVPV-FIKEVSNAEISIGDVAKLSVTVTGIPKPKIQWFFKGVML 93
Query: 390 KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT---------- 539
+ + F N +L I T G+Y+C A+N G A SA L ++
Sbjct: 94 TPSADYKFVFDGNDHSLIILFTKFEDEGEYTCVASNEYGQAVCSASLKISSKGEGQKETE 153
Query: 540 -----------EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSG 686
EG PP+F P+ G A FE V G V W K+++++ +
Sbjct: 154 AEPVETFLEKFEGPCPPYFLKEFKPIHCARGLPAVFEYVVLGEPAPTVTWFKESKQLCTN 213
Query: 687 GNYQISY-LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQL 818
+ I + + S + + D+G Y C A N G+ +CTA+L
Sbjct: 214 VYHTIIHNPDGSGTFIVNDPQREDSGLYVCRAENMWGESTCTAEL 258
Score = 69.3 bits (168), Expect = 1e-11
Identities = 67/234 (28%), Positives = 94/234 (40%), Gaps = 2/234 (0%)
Frame = +3
Query: 60 PEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY--ICRAENSVGEVSSS 233
PEI +SWYKG KL P+ +++ + TL D G Y +C G +S
Sbjct: 6220 PEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKDCQLKDQGNYRLVC------GPHIAS 6273
Query: 234 TFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQT 413
LTV E P++ R L+DV G C S + SWF++GR LK QT
Sbjct: 6274 AKLTVIE----PAWERHLQDVTLKEGQTCTMTCQFSVPN-VKSSWFRNGRLLKPQGRHQT 6328
Query: 414 SFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAV 593
+ V L I G+Y+C + +SA L + P F + +
Sbjct: 6329 AVEHKVHKLTIADVRAEDQGRYTCKYED----LETSAELRIE--AEPIQFTKRIQNIVVS 6382
Query: 594 VGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGD 755
+SA FEC V+ I V W K E+ Y ++TI V D
Sbjct: 6383 EHQSATFECEVSFDDAI-VTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDD 6435
Score = 68.6 bits (166), Expect = 2e-11
Identities = 146/634 (23%), Positives = 231/634 (36%), Gaps = 32/634 (5%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V++ VG++A + +L+ P++ W L + ++ LV + +G
Sbjct: 8709 VELFVGETARFEIELS-EPDVHGQWKLKGEPLTASPDCEIIEDGKKHILVLYNCQLDMTG 8767
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
E +A N+ S+ L V+E LP F L DV+ FEC VS EP +
Sbjct: 8768 EVSFQAANA----KSAANLKVKE--LPLIFITPLSDVKVFEKDEAKFECEVS-REPKTFR 8820
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W K + + ++ +L I G+Y A + +S +LI+ EG
Sbjct: 8821 WLKGTQEITGDDKVELIKDGTKHSLVIKSAAFEDEGKYIFEAEDK----HTSGKLII-EG 8875
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
F PL V A ESA F ++ I+V W K+++ + + + + +
Sbjct: 8876 IRLKFLT-PLKDVTAKERESAVFTVELSHDN-IRVKWFKNDQRLHTSRSVWMDDEGKTHS 8933
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
+T + DT Q A+ S A+L + E P FT KL + E + L
Sbjct: 8934 ITFRDLSIDDTSQIKVEAMGL----SSEAKLTVLEG--DPYFTGKLQDYTG-VEKDEVIL 8986
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+ ++ + V W+K+ EI P+ N I +L +KKA D G YTC D G
Sbjct: 8987 QCEISKADA-PVKWFKDGEEIKPSKNVVIKADGKKRILILKKALKSDIGQYTC----DCG 9041
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
+ + + I++ + V H V V E E + + E I W G + +
Sbjct: 9042 TDKTSGKLNIEDREIKLVRPLH--SVEVMETETARFETEI-SEEDIHANWKLKGEALLQT 9098
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSD--------------------TS 1385
C L + G +A+NV S T+
Sbjct: 9099 PDCEIKEEGKMHFLILHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTA 9158
Query: 1386 KSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK 1565
T + GK EP V E+ TA +V + VKW K
Sbjct: 9159 GETATFDCELSYEDIPVEWYLKGKKL---EPSEKTVEEEATAVLECEVSREN-AKVKWFK 9214
Query: 1566 GKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNV--------- 1718
++ + + I G KL I T D Y C A + NV
Sbjct: 9215 -NGTEILKSKKYEIVADGRVRKLIIHGCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLR 9273
Query: 1719 ---NLQVNERKKQEKIEGDLRAMLKKTPVLKKGA 1811
+LQV E K+ + E ++ K K GA
Sbjct: 9274 PLTDLQVKE-KEMARFECEISRENAKVQWFKDGA 9306
Score = 65.9 bits (159), Expect = 1e-10
Identities = 55/208 (26%), Positives = 74/208 (35%), Gaps = 9/208 (4%)
Frame = +3
Query: 1134 PVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEF 1313
PVF + ++ +S G+ +LS V G +IQW G + PS F F L
Sbjct: 53 PVFIKEVSNAEISIGDVAKLSVTVTGIPKPKIQWFFKGVMLTPSADYKFVFDGNDHSLII 112
Query: 1314 KDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKL---------FF 1466
D G+Y C ASN G + + V+ L +F
Sbjct: 113 LFTKFEDEGEYTCVASNEYGQAVCSASLKISSKGEGQKETEAEPVETFLEKFEGPCPPYF 172
Query: 1467 VSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRD 1646
+ E + I A F V G+P P V W K + IH + D
Sbjct: 173 LKEFKPIHCARGLPAVFEYVVLGEPAPTVTWFKESKQLCTNVYHTIIHNPDGSGTFIVND 232
Query: 1647 TTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ DSGLY C A N GE L V
Sbjct: 233 PQREDSGLYVCRAENMWGESTCTAELLV 260
Score = 61.2 bits (147), Expect = 3e-09
Identities = 50/209 (23%), Positives = 80/209 (38%), Gaps = 22/209 (10%)
Frame = +3
Query: 555 PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTI 734
P F ++ + +G+ A VTG K+ W + +Y+ + N L I
Sbjct: 53 PVFIKEVSNAEISIGDVAKLSVTVTGIPKPKIQWFFKGVMLTPSADYKFVFDGNDHSLII 112
Query: 735 LKVDKGDTGQYTCYAVNEVGKDSCTAQLNIK---------------------ERLIPPSF 851
L D G+YTC A NE G+ C+A L I E PP F
Sbjct: 113 LFTKFEDEGEYTCVASNEYGQAVCSASLKISSKGEGQKETEAEPVETFLEKFEGPCPPYF 172
Query: 852 TKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFK-NNALLLQVK 1028
K+ + + G E V G +V W+K + ++ I + + V
Sbjct: 173 LKEF-KPIHCARGLPAVFEYVVLGEPAPTVTWFKESKQLCTNVYHTIIHNPDGSGTFIVN 231
Query: 1029 KASMGDAGLYTCKVSNDAGSALCTSSIVI 1115
D+GLY C+ N G + CT+ +++
Sbjct: 232 DPQREDSGLYVCRAENMWGESTCTAELLV 260
Score = 57.8 bits (138), Expect = 4e-08
Identities = 64/271 (23%), Positives = 97/271 (35%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VT D A CQL+ + V WY+ +++ YK + L+ +D EY
Sbjct: 9729 VTEFDDAVFSCQLS-REKANVKWYRNGREIKEGKKYKFEKEGSTHRLIIKDCRLDDECEY 9787
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C E+ S L V+E +P R +D+ E G VVF A + + V W
Sbjct: 9788 ACGVEDR----KSRARLFVEE--IPVEIIRPPQDILEAPGTDVVF-LAELNKDKVEVQWL 9840
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
++ + G Q + L I G+Y A + + A+L L
Sbjct: 9841 RNNMVVVQGDKHQMMSEGKIHRLQICNIQPRDQGEYRFIAKDK----EARAKLELAAAPK 9896
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
D L VD VG+ + W K+N + S +
Sbjct: 9897 IKTGDQDLV-VD--VGQPLTMVVPYDAYPKAEAEWFKENEPLSSK---TVDTTAEQTSFR 9950
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI 824
IL+ KGD G+Y N+ GK L +
Sbjct: 9951 ILEAKKGDKGRYKIVLQNKHGKAEAFINLRV 9981
Score = 55.5 bits (132), Expect = 2e-07
Identities = 58/230 (25%), Positives = 98/230 (42%), Gaps = 1/230 (0%)
Frame = +3
Query: 321 VFECAVSGSEP-ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATN 497
VFE + + P I +SW+K L+ + S + TL + G Y
Sbjct: 6210 VFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKDCQLKDQGNYRLVC-- 6267
Query: 498 PIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI 677
G +SA+L + E P ++ L V G++ C + +K +W ++ R +
Sbjct: 6268 --GPHIASAKLTVIE----PAWERHLQDVTLKEGQTCTMTCQFS-VPNVKSSWFRNGRLL 6320
Query: 678 RSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK 857
+ G +Q + LTI V D G+YTC + +A+L I+ P FTK
Sbjct: 6321 KPQGRHQTAVEHKVHKLTIADVRAEDQGRYTC----KYEDLETSAELRIEAE--PIQFTK 6374
Query: 858 KLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNN 1007
++ + + +E S E V+ I V WYK E+ T + + F+N+
Sbjct: 6375 RI-QNIVVSEHQSATFECEVSFDDAI-VTWYKGPTEL--TESQKYNFRND 6420
Score = 53.1 bits (126), Expect = 9e-07
Identities = 32/100 (32%), Positives = 44/100 (44%)
Frame = +3
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ ++V K+P P D + V EGE L + R + W K G+E+K SDR +
Sbjct: 11262 SENVVAKDPDCQPTIDMETHDIVVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 11321
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
+ +A LE ADAG Y N GS T V
Sbjct: 11322 MKNDHISAHLEVPKSVHADAGIYTITLENKLGSATGSINV 11361
>ref|XP_547438.2| PREDICTED: similar to High Incidence of Males (increased X chromosome
loss) family member (him-4) [Canis familiaris].
Length = 5637
Score = 191 bits (485), Expect = 2e-48
Identities = 146/581 (25%), Positives = 255/581 (43%), Gaps = 5/581 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G SASL+C+ P ++WYK + T + + + L + + +D+G
Sbjct: 3071 VNVREGTSASLECESNAVPPPVITWYKNGQMI--TESTHLEILADGQMLHIKKAEVSDTG 3128
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSR-QLRDVQETVGLPVVFECAVSGSEPISV 362
+Y+CRA N G + L V +PPS + + V ET+ PV C +G P +
Sbjct: 3129 QYVCRAINVAGRDDKNFHLNVY---VPPSIEGPENKVVVETISNPVTLTCDATGIPPPMI 3185
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+ +P+++ +++ L + L I ++ S +G Y+C A+N G A + L +
Sbjct: 3186 AWLKNHKPIENSDSLEVHILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKNYILSIQV 3245
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ +IP + V + GE+ + C+ G + W +D + I + +I + +
Sbjct: 3246 PPSIAGAEIP-SEVSVLQGENVELACNANGIPTPLIQWLRDGKPINTSETERIRVTADGS 3304
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF--TKKLSETVEETEGNS 896
LTI + G+YTC A N G++ LN+ +PP+ KK +E + S
Sbjct: 3305 TLTIYGALPSNMGKYTCVATNSAGEEDRIFNLNV---YVPPAIRGNKKEAEKLMALVDTS 3361
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
+E R G+ P + W KN + + + I + ++++ +A + D +YTC SN
Sbjct: 3362 INIECRATGTPPPQINWLKNGLPL--PLSSHIRLLSGGQVIRIVRAQVSDVAMYTCVASN 3419
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHL--TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
AG S+ + PP D + +T+ +G + C G+ R+ WLK G+
Sbjct: 3420 RAGVDNKHYSLQV---FVPPNLDNSMGTEEITIVKGSSTSMRCFTDGTPTPRMSWLKDGQ 3476
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
+ + R + S VL+ + D+G Y+C ASN AG + +K +
Sbjct: 3477 PLGLNTRLTISTQG--MVLQLLNAETEDSGRYICIASNEAG-EVNKHFI--------LKV 3525
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
++G EP I V+ G P P + W K R L Q + I
Sbjct: 3526 LEPPHINGS----EEPVEISVIVNNPLELTCLASGIPTPKITWMK-DGRPLPQTDQ--IQ 3578
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
G L + D+G Y C+A + G+ + ++V+
Sbjct: 3579 TLGGGEVLRLSSAQVEDTGRYTCLASSTAGDDDKEYLVRVH 3619
Score = 188 bits (477), Expect = 2e-47
Identities = 158/576 (27%), Positives = 231/576 (40%), Gaps = 3/576 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V V + L+C+ AG P + W K + L +A+ + F N + D+G Y
Sbjct: 1934 VVVNNPIQLECKAAGNPLPAIKWDKDNRPL--SASTGVTFLNRGQIIDIESAQITDAGIY 1991
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A NS G ++ F ++Q +PPS S V V V EC G S++W
Sbjct: 1992 KCMAINSAG--ATELFYSLQVH-VPPSISGSNSMVAVVVNNLVRLECEARGIPAPSLTWL 2048
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDG P+ N L L + S G+Y+C A N G L +
Sbjct: 2049 KDGSPVSSFAN-GIQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRIYV--- 2104
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP + ++ +S + C P + W KD R + IS EN + L
Sbjct: 2105 PPNIMGEEQNISVLISQSVELLCQSDAIPPPTLTWLKDGRPLLKKPGLSIS--ENGSVLK 2162
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET--EGNSFRL 905
I DTG+YTC A N GK +NI +PPS E + T EGN L
Sbjct: 2163 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNI---WVPPSIYGS-DEPAQLTVIEGNLISL 2218
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+G P ++ W K + P + + + LQ+ A DAGLYTC SN AG
Sbjct: 2219 LCESSGIPPPNLIWKKRGSPVLPDSAGRVRTFSGGRQLQISVAEKSDAGLYTCVASNVAG 2278
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
+A + + H T + V+ G+ + L C V+G ++ W+K GR +
Sbjct: 2279 TAKKDYGLQVYIRPTISNSGNHPTEIIVTRGKSISLECEVQGIPQPKVTWMKDGRPLTKG 2338
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ +L+ K++ +D G YVC A NVAG K ++
Sbjct: 2339 R--GMEILDEGRILQLKNIHISDTGRYVCVAVNVAGMTDRKYDLSVHTPPSIIGNHGI-- 2394
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWR-QLNQGGRIFIHQKGD 1622
P++I VVEK + + + G P+P++ W K W L+ RI
Sbjct: 2395 ----------PENISVVEKNSVSLTCEASGIPLPSITWLKDGWPVSLSSSVRIL----SG 2440
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
L + T D+G Y CV N GE L V
Sbjct: 2441 GRTLRLMQTRLEDAGQYTCVVRNAAGEERKIFGLSV 2476
Score = 172 bits (437), Expect = 8e-43
Identities = 154/608 (25%), Positives = 242/608 (39%), Gaps = 10/608 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + +L C++ GTP + WYK D ++ ++T + NN L +V D G
Sbjct: 1372 VSVLINQLTNLFCEVEGTPSPIIMWYKDDVQVSESST--IQIVNNGKILKLFKVTPEDVG 1429
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C+A N G +S + + + +PP+ + +V + EC V G+ +
Sbjct: 1430 RYSCKAVNIAG--TSQKYFNI-DVLVPPTIIGANSPNEVSVVLNHDTTLECQVKGTPFPA 1486
Query: 360 VSWFKDGRPL-KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
+ WFKDG+PL + PNI+ LD L++ RS G+Y C +N G + RL +
Sbjct: 1487 IHWFKDGKPLFLEDPNIE--LLDKGQVLHLKNARRSDKGRYQCAVSNAAGKQTKDIRLTV 1544
Query: 537 -----TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
+G N + A++ EC G V W KD + + S Q
Sbjct: 1545 YIPPSIKGGN------VTTEISALINSIIKLECETRGLPMPAVTWYKDGQPVISSS--QA 1596
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
Y++ L I + D+ Y+C N G + Q+++ +PP L + +
Sbjct: 1597 LYVDKGQFLHIPRAQVSDSATYSCRVTNVAGTAEKSFQVDV---YVPPMIEGDLGAPLNK 1653
Query: 882 --TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGL 1055
+S LE + G+ P + W K+ + + + N I + L++ A D G
Sbjct: 1654 QVVIAHSLTLECKATGNPPPVLTWLKDGIPVKASDN--IRTEGGGKKLEIMSALEADRGQ 1711
Query: 1056 YTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQW 1235
Y C ++ AG + + P D+ + V L+L C V GS I W
Sbjct: 1712 YVCVATSVAGEKEIKYKVDVLVPPAIEGGDE-TSYFIVMVNNLLELDCQVTGSPTPTIMW 1770
Query: 1236 LKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXX 1415
LK G+ I +R F L +D G Y C A+N+AG + +VT
Sbjct: 1771 LKDGQLI--DERDGFKVLLNGRKLVIAQAQVSDTGLYRCVATNIAGDRKKEFEVTVHVPP 1828
Query: 1416 XXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGG 1595
S P +V+ T G P P++ W K G
Sbjct: 1829 TIKS--------------SGPSERAIVKYKPITLQCIANGIPNPSITWLKDGQPVNTAQG 1874
Query: 1596 RIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRA 1775
+ I G L+I D+G Y CVA N GE ++ L V+E E D
Sbjct: 1875 NLKIQSSG--RVLQIAKALMEDAGRYTCVATNAAGETRQHLQLHVHEPPSLE----DAGK 1928
Query: 1776 MLKKTPVL 1799
ML +T V+
Sbjct: 1929 MLNETVVV 1936
Score = 170 bits (431), Expect = 4e-42
Identities = 152/577 (26%), Positives = 232/577 (40%), Gaps = 10/577 (1%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENS 212
+LQC G P ++W K + TA + +++ L + D+G Y C A N+
Sbjct: 1847 TLQCIANGIPNPSITWLKDGQPVN-TAQGNLKIQSSGRVLQIAKALMEDAGRYTCVATNA 1905
Query: 213 VGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGL--PVVFECAVSGSEPISVSWFKDGRP 386
GE L V E PPS + + ETV + P+ EC +G+ ++ W KD RP
Sbjct: 1906 AGETRQHLQLHVHE---PPSLEDAGKMLNETVVVNNPIQLECKAAGNPLPAIKWDKDNRP 1962
Query: 387 LKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFD 566
L + +FL+ ++I + AG Y C A N SA ++ + PP
Sbjct: 1963 LSASTGV--TFLNRGQIIDIESAQITDAGIYKCMAIN---SAGATELFYSLQVHVPPSIS 2017
Query: 567 IPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVD 746
+ V VV EC G + W KD + S N I L L +
Sbjct: 2018 GSNSMVAVVVNNLVRLECEARGIPAPSLTWLKDGSPVSSFAN-GIQVLSGGRILALTSAQ 2076
Query: 747 KGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGS 926
DTG+YTC AVN G+ L I +PP+ + + + S L +
Sbjct: 2077 ISDTGRYTCVAVNAAGEKQRDIDLRI---YVPPNIMGE-EQNISVLISQSVELLCQSDAI 2132
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS 1106
P ++ W K+ + I+ N +L+++ A + D G YTC+ +N AG +
Sbjct: 2133 PPPTLTWLKDGRPLLKKPGLSIS--ENGSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYN 2190
Query: 1107 IVIKEPKKPPVF-DQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFS 1283
+ I P P ++ +TV EG + L C G P + W K G + P
Sbjct: 2191 VNIWVP--PSIYGSDEPAQLTVIEGNLISLLCESSGIPPPNLIWKKRGSPVLPDSAGRVR 2248
Query: 1284 FANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLF 1463
+G L+ K+DAG Y C ASNVAG T+K
Sbjct: 2249 TFSGGRQLQISVAEKSDAGLYTCVASNVAG--TAKKDYGLQVYIRPTISNSG-------- 2298
Query: 1464 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW-------TKGKWRQLNQGGRIFIHQKGD 1622
+ P I V + + +V G P P V W TKG+ ++ GRI
Sbjct: 2299 --NHPTEIIVTRGKSISLECEVQGIPQPKVTWMKDGRPLTKGRGMEILDEGRI------- 2349
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
L++++ +D+G Y CVA N G + +L V+
Sbjct: 2350 ---LQLKNIHISDTGRYVCVAVNVAGMTDRKYDLSVH 2383
Score = 167 bits (423), Expect = 3e-41
Identities = 146/596 (24%), Positives = 241/596 (40%), Gaps = 20/596 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + +L+CQ+ GTP + W+K D K + + L +D G
Sbjct: 1465 VSVVLNHDTTLECQVKGTPFPAIHWFK-DGKPLFLEDPNIELLDKGQVLHLKNARRSDKG 1523
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFS--RQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C N+ G+ + LTV +PPS ++ + + EC G +
Sbjct: 1524 RYQCAVSNAAGKQTKDIRLTVY---IPPSIKGGNVTTEISALINSIIKLECETRGLPMPA 1580
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V+W+KDG+P+ Q ++D L+I + S + YSC TN G+A S ++ +
Sbjct: 1581 VTWYKDGQPVISSS--QALYVDKGQFLHIPRAQVSDSATYSCRVTNVAGTAEKSFQVDVY 1638
Query: 540 EGRNPPFFDIPL-APVD--AVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
PP + L AP++ V+ S EC TG P + W KD +++ N +
Sbjct: 1639 V---PPMIEGDLGAPLNKQVVIAHSLTLECKATGNPPPVLTWLKDGIPVKASDNIRTE-- 1693
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE- 887
L I+ + D GQY C A + G+ ++++ L+PP+ E +ET
Sbjct: 1694 GGGKKLEIMSALEADRGQYVCVATSVAGEKEIKYKVDV---LVPPAI-----EGGDETSY 1745
Query: 888 -----GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAG 1052
N L+ +V GS ++ W K+ I ++ L+ + +A + D G
Sbjct: 1746 FIVMVNNLLELDCQVTGSPTPTIMWLKDGQLIDERDGFKVLLNGRKLV--IAQAQVSDTG 1803
Query: 1053 LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQ 1232
LY C +N AG + + P P + + + + + + L C G I
Sbjct: 1804 LYRCVATNIAGDRKKEFEVTVHVP--PTIKSSGPSERAIVKYKPITLQCIANGIPNPSIT 1861
Query: 1233 WLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXX 1412
WLK G+ + + + + VL+ DAG Y C A+N AG ++
Sbjct: 1862 WLKDGQPVNTAQG-NLKIQSSGRVLQIAKALMEDAGRYTCVATNAAGETRQHLQL----- 1915
Query: 1413 XXXXXXXXXXXVDGKLFFVSEPQSIR---------VVEKTTATFIAKVGGDPIPNVKWTK 1565
V EP S+ VV K G+P+P +KW K
Sbjct: 1916 -----------------HVHEPPSLEDAGKMLNETVVVNNPIQLECKAAGNPLPAIKWDK 1958
Query: 1566 GKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
R L+ + +G ++I TD+G+Y+C+A N G E +LQV+
Sbjct: 1959 DN-RPLSASTGVTFLNRGQI--IDIESAQITDAGIYKCMAINSAGATELFYSLQVH 2011
Score = 167 bits (422), Expect = 5e-41
Identities = 151/578 (26%), Positives = 224/578 (38%), Gaps = 9/578 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ VTV +L C+ AG P+ + W K L + + +LV +D+
Sbjct: 3815 ITVTVNVQTTLACEAAGIPKPSIKWKKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 3874
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C N GE + LTVQ +PPS + + D+ T P + C SG S+
Sbjct: 3875 TYECTVTNDAGEDQRTVDLTVQ---VPPSIADEPTDLLVTKHAPTIITCTASGVPFPSIH 3931
Query: 366 WFKDG---RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
W K+G P +DG I +S + IF T + AG+Y+C A N GSA L +
Sbjct: 3932 WTKNGIRLLPREDGYRILSS-----GAIEIFATQLNHAGRYTCIARNAAGSAHRHVTLYV 3986
Query: 537 TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
E PP + +D +V C TGT + W K+ + + G + L N
Sbjct: 3987 QE---PPVIQPQPSELDVIVNNPILLPCEATGTPSPFITWQKEGINVITSGKSH-AVLPN 4042
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
L I + + D G Y C A N G +LN++ +PP + E + +
Sbjct: 4043 GG-LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ---VPPVISPHPKEYITAVD-KP 4097
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
L G + W+K+ I + I ++ LQ+ A GDAG YTC +N
Sbjct: 4098 ISLPCEADGLPAPDITWHKDGHAIVESIRQRIL---SSGALQIAFAQPGDAGQYTCMAAN 4154
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
AGS+ ++ + + P + D H TVSE L C G I W K
Sbjct: 4155 VAGSSSMSTKLTVHVPPRIQSTDVH---YTVSENSQALLPCMADGIPTPVINWKK----- 4206
Query: 1257 KPSDRCSFSFANGTAVLE------FKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXX 1418
D + G +E ++V DAG Y C A+N AG DT +T
Sbjct: 4207 ---DNVLLANLLGKYTIEPYGELILENVVLEDAGTYTCVANNAAGEDTHMVSLTVHVLPT 4263
Query: 1419 XXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR 1598
F P + + + K G P+P + WT N
Sbjct: 4264 ---------------FTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN-----NNIIP 4303
Query: 1599 IFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIES 1712
++L I +K DSG Y C A N G +++
Sbjct: 4304 AHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKA 4341
Score = 159 bits (401), Expect = 1e-38
Identities = 145/583 (24%), Positives = 232/583 (39%), Gaps = 8/583 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDT--KLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + SL C+++G P +SW K + KL A R TL + +D G
Sbjct: 2978 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNALIVPGGR----TLQIIRAKVSDGG 3033
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF----SRQLRDVQETVGLPVVFECAVSGSEP 353
EY C A N GE LTV +PPS S L V G EC + P
Sbjct: 3034 EYTCIAINQAGESKKKVSLTVY---VPPSIKDHGSESLSVVNVREGTSASLECESNAVPP 3090
Query: 354 ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
++W+K+G+ + + +++ L + L+I + + S GQY C A N G + L
Sbjct: 3091 PVITWYKNGQMITESTHLE--ILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLN 3148
Query: 534 LTEGRNPPFFDIPLAPVDA-VVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
+ PP + P V + C TG P +AW K+++ I + + ++ L
Sbjct: 3149 VYV---PPSIEGPENKVVVETISNPVTLTCDATGIPPPMIAWLKNHKPIENSDSLEVHIL 3205
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKLSETVEETE 887
+ L I + D+G YTC A N GK L+I+ +PPS ++ V +
Sbjct: 3206 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKNYILSIQ---VPPSIAGAEIPSEVSVLQ 3262
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
G + L G + W ++ I+ + I + L + A + G YTC
Sbjct: 3263 GENVELACNANGIPTPLIQWLRDGKPINTSETERIRVTADGSTLTIYGALPSNMGKYTCV 3322
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
+N AG ++ + P + + + + C G+ P +I WLK G
Sbjct: 3323 ATNSAGEEDRIFNLNVYVPPAIRGNKKEAEKLMALVDTSINIECRATGTPPPQINWLKNG 3382
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
+ S +G V+ +D Y C ASN AG D +
Sbjct: 3383 LPLPLSSH--IRLLSGGQVIRIVRAQVSDVAMYTCVASNRAGVDNKHYSLQVF------- 3433
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
V L + I +V+ ++ + G P P + W K + L R+ I
Sbjct: 3434 ------VPPNLDNSMGTEEITIVKGSSTSMRCFTDGTPTPRMSWLKDG-QPLGLNTRLTI 3486
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+G L++ + DSG Y C+A N+ GE+ + L+V E
Sbjct: 3487 STQG--MVLQLLNAETEDSGRYICIASNEAGEVNKHFILKVLE 3527
Score = 158 bits (399), Expect = 2e-38
Identities = 141/579 (24%), Positives = 222/579 (38%), Gaps = 4/579 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V V + L+C+ G P ++W K + + A + + L +D+G
Sbjct: 2023 VAVVVNNLVRLECEARGIPAPSLTWLKDGSPVSSFAN-GIQVLSGGRILALTSAQISDTG 2081
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C A N+ GE L + +PP+ + +++ + V C P +++
Sbjct: 2082 RYTCVAVNAAGEKQRDIDLRIY---VPPNIMGEEQNISVLISQSVELLCQSDAIPPPTLT 2138
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W KDGRPL P + S +N + L I G+Y+C ATN G + + +
Sbjct: 2139 WLKDGRPLLKKPGLSIS--ENGSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVP 2196
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
+ D P A + + G C +G P + W K + ++
Sbjct: 2197 PSIYGSDEP-AQLTVIEGNLISLLCESSGIPPPNLIWKKRGSPVLPDSAGRVRTFSGGRQ 2255
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE--ETEGNSF 899
L I +K D G YTC A N G L + I P+ + + E T G S
Sbjct: 2256 LQISVAEKSDAGLYTCVASNVAGTAKKDYGLQV---YIRPTISNSGNHPTEIIVTRGKSI 2312
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
LE V G V W K+ + EI + +LQ+K + D G Y C N
Sbjct: 2313 SLECEVQGIPQPKVTWMKDGRPLTKGRGMEIL--DEGRILQLKNIHISDTGRYVCVAVNV 2370
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTP--VTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
AG + + P P + H P ++V E + L+C G I WLK G
Sbjct: 2371 AGMTDRKYDLSVHTP--PSIIGNHGIPENISVVEKNSVSLTCEASGIPLPSITWLKDGWP 2428
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
+ S S +G L DAG Y C N AG + ++
Sbjct: 2429 VSLSS--SVRILSGGRTLRLMQTRLEDAGQYTCVVRNAAGEERKIFGLSVL--------- 2477
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
V ++ + + ++V EK + T +V G+P+P + W K QL Q
Sbjct: 2478 ----VPPRIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKD--GQLLQEDDTHHIM 2531
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
G L+I + + +G Y C+A N G+ + +L V
Sbjct: 2532 SGGHF-LKITNAQVSHTGRYACLASNTAGDKSKSFSLNV 2569
Score = 154 bits (389), Expect = 3e-37
Identities = 150/600 (25%), Positives = 236/600 (39%), Gaps = 25/600 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + SL C+ P ++W+K T L ++ TL +++G
Sbjct: 2587 VTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI--LPGGRTLQILNAQEDNAG 2644
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSR--------QLRDVQETVGLPVVFECAVS 341
Y C A N GE+ + V +PP ++ ++V+ V + EC
Sbjct: 2645 RYSCIATNEAGEMIKHYEVKVY---IPPIINKGDLLGPGLSPKEVKIKVNNTLTLECEAY 2701
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
S+SW+KDG+PLK ++ + + TL I + S G+Y+C A+N G
Sbjct: 2702 AIPSASLSWYKDGQPLKSDDHVNIAASGH--TLQIKEAQISDTGRYTCVASNIAGEDELD 2759
Query: 522 ARLILTEGRNPPFFDIPLAPV-------------DAVVGESADFECHVTGTQPIKVAWAK 662
+ + + PP F L + D ++ C P + W K
Sbjct: 2760 FDVNI---QVPPSFQ-KLWEIGNMLDTGRSGEAKDVIINNPISLYCETNAAPPPTLTWYK 2815
Query: 663 DNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP 842
D R + S ++ L L I + D G+YTC AVNE G+DS + + L+P
Sbjct: 2816 DGRPLTSSD--RVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV---LLP 2870
Query: 843 PSFTKKLSETVEETE---GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNAL 1013
P S+ EE S +E +GS +W K+ + + + F +N
Sbjct: 2871 PVIKGANSDLPEEVTVLVNKSTLMECLSSGSPAPRNSWQKDGQPLLEDEHHK--FVSNGR 2928
Query: 1014 LLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQL 1193
+LQ+ + D G Y C N AGSA ++ + P P V + +TV F+ L
Sbjct: 2929 ILQILNTQITDIGRYVCIAENTAGSAKKYFNLNVHVP--PSVIGPNPENLTVVVNNFISL 2986
Query: 1194 SCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAG 1373
+C V G P + WLK + IK + G L+ +D G+Y C A N AG
Sbjct: 2987 TCEVSGFPPPDLSWLKNEQPIKLNTNA--LIVPGGRTLQIIRAKVSDGGEYTCIAINQAG 3044
Query: 1374 SDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS-IRVVEKTTATFIAKVGGDPIPN 1550
K +T SE S + V E T+A+ + P P
Sbjct: 3045 ESKKKVSLTVYVPPSIKDHG------------SESLSVVNVREGTSASLECESNAVPPPV 3092
Query: 1551 VKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ W K + + + + I D L I+ +D+G Y C A N G + N +L V
Sbjct: 3093 ITWYK-NGQMITESTHLEI--LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV 3149
Score = 152 bits (383), Expect = 1e-36
Identities = 151/595 (25%), Positives = 250/595 (42%), Gaps = 12/595 (2%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V +GD+ ++C+ +GTP V W+KGD +LRP+ + + L + D+G+Y
Sbjct: 715 VALGDTTVMECKSSGTPLPQVKWFKGDLELRPSPF--LIIDPLLGLLKIQETQDLDAGDY 772
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A N G + L V PP F ++ DV +G V C V G + W
Sbjct: 773 TCVAVNDAGRAAGKITLDVGS---PPVFIQEPADVSVEIGSNVTLPCYVQGYPEPKIKWR 829
Query: 372 K-DGRPLKDGPNIQTSFLDNVATLNIFQTD--RSFAGQYSCTATNPIGSASSSARLILTE 542
+ D P+ P S + + T +F ++ + G Y C A N G S + +T
Sbjct: 830 RSDNMPIFSRP-FSVSSISQLRTGALFISNLWANDKGTYICEAENQFGKIQSQTTVTVT- 887
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPI-KVAWAKDNREIRSGGNYQISYLENS 719
G P I + + G+ C + PI + W K N + Y + S
Sbjct: 888 GLVAPLIGISPSVTSVIEGQQLTLPCALLAGNPIPERRWIK-NSAMLVQNPYITVRSDGS 946
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
H+ +++ G G+YTC A N G + T +++ ++P + + + EG
Sbjct: 947 LHIERVRLQDG--GKYTCVASNVAGTVNKTTTVDV--HVLPT--IQHGQQVLSTIEGIPV 1000
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L + +G S+ W K E+ T++ + + + L V ++G Y C +N
Sbjct: 1001 TLPCKASGIPKPSIIWSKKG-ELISTSSAKFSAGADG-SLYVASPGGEESGEYVCTATNA 1058
Query: 1080 AGSALCTSSIVIKEPKKPPVF-DQH------LTPVTVSEGEFLQLSCHVRGSEPIRIQWL 1238
AG A + + +P VF DQ ++V GE + L C V+ P I W
Sbjct: 1059 AGYA--KRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSIPPPIITWA 1116
Query: 1239 KAGREIKP-SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXX 1415
K + I P S R +F + ++E + +D+G Y+C A+N+AG+ T K+
Sbjct: 1117 KETQLISPFSPRHTFLPSGSMKIIETR---ISDSGMYLCVATNIAGNVTQSVKLN----- 1168
Query: 1416 XXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGG 1595
V K+ + ++V ++ A+ G P+P + W KG L G
Sbjct: 1169 --------VHVPPKIQRGPKLMKVQVGQRVDIPCTAQ--GMPLPVITWFKGGSAMLVDGV 1218
Query: 1596 RIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIE 1760
+ H + L I +D+G+Y CVA N G E+ + L V E E +E
Sbjct: 1219 Q---HISNSDGTLSIDQAMLSDAGIYTCVATNIAGSDETEITLHVQEPPTLEDLE 1270
Score = 149 bits (375), Expect = 1e-35
Identities = 136/567 (23%), Positives = 220/567 (38%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENS 212
+L+C+ P ++W K +L+ AT ++ + L N D ND+ Y C A N
Sbjct: 3642 TLECKSDAVPPPVITWLKNGERLQ--ATPRVRILSGGRYLQVNNADLNDTANYTCVASNI 3699
Query: 213 VGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLK 392
G+ + LTV +PP+ + V + + V EC G ++W KDG L
Sbjct: 3700 AGKTTREFILTVN---VPPNIKSGPQSVVIHLNMSAVLECLAEGVPAPRITWRKDGAVLS 3756
Query: 393 DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIP 572
+ + S L+N L+I + G+Y C ATN +A + R I + PP +
Sbjct: 3757 -ASHARYSILEN-GFLHIQSAHVTDTGRYLCMATN---AAGTDRRRIDLQVHVPPSIALG 3811
Query: 573 LAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKG 752
+ V C G + W K+ + N L +S L I+
Sbjct: 3812 PTNITVTVNVQTTLACEAAGIPKPSIKWKKNGHLLNVDQNQNSYRLLSSGSLVIISPSVD 3871
Query: 753 DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQP 932
DT Y C N+ G+D T L ++ +PPS + ++ + + + +G
Sbjct: 3872 DTATYECTVTNDAGEDQRTVDLTVQ---VPPSIADEPTDLLVTKHAPTI-ITCTASGVPF 3927
Query: 933 ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIV 1112
S+ W KN + + P + + A +++ + AG YTC N AGSA ++
Sbjct: 3928 PSIHWTKNGIRLLPREDGYRILSSGA--IEIFATQLNHAGRYTCIARNAAGSAHRHVTLY 3985
Query: 1113 IKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFAN 1292
++E PPV + + V + L C G+ I W K G + S + N
Sbjct: 3986 VQE---PPVIQPQPSELDVIVNNPILLPCEATGTPSPFITWQKEGINVITSGKSHAVLPN 4042
Query: 1293 GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVS 1472
G L+ + DAG Y+C A N AG+ K K+ V
Sbjct: 4043 GG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLN---------------VQVPPVISP 4085
Query: 1473 EPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTT 1652
P+ + + G P P++ W K + + R I G L+I
Sbjct: 4086 HPKEYITAVDKPISLPCEADGLPAPDITWHK-DGHAIVESIRQRILSSG---ALQIAFAQ 4141
Query: 1653 KTDSGLYRCVAFNKHGEIESNVNLQVN 1733
D+G Y C+A N G + L V+
Sbjct: 4142 PGDAGQYTCMAANVAGSSSMSTKLTVH 4168
Score = 149 bits (375), Expect = 1e-35
Identities = 150/594 (25%), Positives = 223/594 (37%), Gaps = 6/594 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDS---N 176
V + + SA L+C G P ++W K L + H R ++ F + S
Sbjct: 3724 VVIHLNMSAVLECLAEGVPAPRITWRKDGAVLSAS-----HARYSILENGFLHIQSAHVT 3778
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
D+G Y+C A N+ G L V +PPS + ++ TV + C +G
Sbjct: 3779 DTGRYLCMATNAAGTDRRRIDLQVH---VPPSIALGPTNITVTVNVQTTLACEAAGIPKP 3835
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
S+ W K+G L N + L + +L I Y CT TN G + L +
Sbjct: 3836 SIKWKKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNDAGEDQRTVDLTV 3895
Query: 537 TEGRNPPFFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDN-REIRSGGNYQISY 707
+ PP I P D +V + A C +G + W K+ R + Y+I
Sbjct: 3896 ---QVPP--SIADEPTDLLVTKHAPTIITCTASGVPFPSIHWTKNGIRLLPREDGYRIL- 3949
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
+S + I G+YTC A N G L ++E PP + SE ++
Sbjct: 3950 --SSGAIEIFATQLNHAGRYTCIARNAAGSAHRHVTLYVQE---PPVIQPQPSE-LDVIV 4003
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
N L G+ + W K + + + N L Q+ +A DAG Y C
Sbjct: 4004 NNPILLPCEATGTPSPFITWQKEGINVITSGKSHAVLPNGGL--QISRAVREDAGTYMCV 4061
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
N AG+AL + ++ P PV H + + + L C G I W K G
Sbjct: 4062 AQNPAGTALGKIKLNVQVP---PVISPHPKEYITAVDKPISLPCEADGLPAPDITWHKDG 4118
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
I S R + L+ DAG Y C A+NVAGS + +K+T
Sbjct: 4119 HAIVESIRQRIL---SSGALQIAFAQPGDAGQYTCMAANVAGSSSMSTKLTVHVPPRIQ- 4174
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
S V E + A G P P + W K N G+ I
Sbjct: 4175 --------------STDVHYTVSENSQALLPCMADGIPTPVINWKKDNVLLANLLGKYTI 4220
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDL 1769
G+ L + + D+G Y CVA N GE V+L V+ ++ GD+
Sbjct: 4221 EPYGE---LILENVVLEDAGTYTCVANNAAGEDTHMVSLTVHVLPTFTELPGDV 4271
Score = 144 bits (364), Expect = 2e-34
Identities = 151/577 (26%), Positives = 223/577 (38%), Gaps = 4/577 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V V + L C+ GTP ++W K + + K H L ++ D+G Y
Sbjct: 4001 VIVNNPILLPCEATGTPSPFITWQKEGINVITSG--KSHAVLPNGGLQISRAVREDAGTY 4058
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
+C A+N G L VQ +PP S ++ V P+ C G ++W
Sbjct: 4059 MCVAQNPAGTALGKIKLNVQ---VPPVISPHPKEYITAVDKPISLPCEADGLPAPDITWH 4115
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDG + + +I+ L + A L I AGQY+C A N GS+S S +L +
Sbjct: 4116 KDGHAIVE--SIRQRILSSGA-LQIAFAQPGDAGQYTCMAANVAGSSSMSTKLTV---HV 4169
Query: 552 PPFFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDNREIRSG-GNYQISYLENSA 722
PP I V V E++ C G + W KDN + + G Y I E
Sbjct: 4170 PP--RIQSTDVHYTVSENSQALLPCMADGIPTPVINWKKDNVLLANLLGKYTI---EPYG 4224
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + V D G YTC A N G+D+ L + + P+FT+ L V +G R
Sbjct: 4225 ELILENVVLEDAGTYTCVANNAAGEDTHMVSLTVH---VLPTFTE-LPGDVSLNKGEQLR 4280
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L + G + W NN I P + N L +++ S D+G Y C N
Sbjct: 4281 LSCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVIERVSKEDSGTYVCTAENSV 4336
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSE-GEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
G + +KE PPVF + G L+C V+G IQW + G +I+
Sbjct: 4337 GFVKAIGFVYVKE---PPVFKGDYPSNWIEPLGGNAILNCEVKGDPAPTIQWSRKGMDIE 4393
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
+ R NG+ L DAGDY C A+N AG +T
Sbjct: 4394 INHRIR-QLVNGS--LAIYGTVNEDAGDYTCVATNDAGVVERSMSLT------------- 4437
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
+ EP + + G+P P + W++ + + R+ +
Sbjct: 4438 --LQSPPIITLEPVETVINAGGKVILNCQATGEPYPTITWSR-QGHSIPWDDRVNVLSNN 4494
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
L I K D+ Y CVA N G + V + V
Sbjct: 4495 ---SLHIAAAQKEDTSEYECVARNLMGSVLVRVPVTV 4528
Score = 143 bits (361), Expect = 5e-34
Identities = 143/585 (24%), Positives = 233/585 (39%), Gaps = 15/585 (2%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G +L C+ +G P+ + W K +L T++ K + +L +SGEY+C
Sbjct: 997 GIPVTLPCKASGIPKPSIIWSKKG-ELISTSSAKFSAGAD-GSLYVASPGGEESGEYVCT 1054
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLR-----DVQETVGLPVVFECAVSGSEPISVS 365
A N+ G LTV + R L ++ G V C V P ++
Sbjct: 1055 ATNAAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSIPPPIIT 1114
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W K+ + + T FL + ++ I +T S +G Y C ATN G+ + S +L +
Sbjct: 1115 WAKETQLISPFSPRHT-FLPS-GSMKIIETRISDSGMYLCVATNIAGNVTQSVKLNV--- 1169
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP + VG+ D C G + W K + G IS + +
Sbjct: 1170 HVPPKIQRGPKLMKVQVGQRVDIPCTAQGMPLPVITWFKGGSAMLVDGVQHISNSDGT-- 1227
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR- 902
L+I + D G YTC A N G D L+++E PP+ E +E F+
Sbjct: 1228 LSIDQAMLSDAGIYTCVATNIAGSDETEITLHVQE---PPTL-----EDLEPPYNTPFQE 1279
Query: 903 --LEGRVA------GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
R+A G+ ++ W N E+ I+ + LL + + D G Y
Sbjct: 1280 RVANQRIAFPCPAKGTPKPTIKWIWNGREL-TGREPGISILEDGTLLVIASVTPYDNGEY 1338
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFD-QHLTPVTVSEGEFLQLSCHVRGSEPIRIQW 1235
C N+AG+ ++ + P P + D +H+T V+V + L C V G+ I W
Sbjct: 1339 ICVAVNEAGTTEKKYNLKVHVP--PVIKDKEHITNVSVLINQLTNLFCEVEGTPSPIIMW 1396
Query: 1236 LKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXX 1415
K +++ S+ + N +L+ VT D G Y CKA N+AG+ +
Sbjct: 1397 YKD--DVQVSESSTIQIVNNGKILKLFKVTPEDVGRYSCKAVNIAGTSQKYFNI------ 1448
Query: 1416 XXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGG 1595
V + + P + VV T +V G P P + W K +
Sbjct: 1449 -------DVLVPPTIIGANSPNEVSVVLNHDTTLECQVKGTPFPAIHWFKDGKPLFLEDP 1501
Query: 1596 RIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
I + KG L +++ ++D G Y+C N G+ ++ L V
Sbjct: 1502 NIELLDKGQ--VLHLKNARRSDKGRYQCAVSNAAGKQTKDIRLTV 1544
Score = 143 bits (360), Expect = 7e-34
Identities = 147/588 (25%), Positives = 230/588 (39%), Gaps = 12/588 (2%)
Frame = +3
Query: 3 PVKVTV--GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSN 176
P ++TV G+ SL C+ +G P + W K + + P + ++ + L + + +
Sbjct: 2205 PAQLTVIEGNLISLLCESSGIPPPNLIWKKRGSPVLPDSAGRVRTFSGGRQLQISVAEKS 2264
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
D+G Y C A N G L +
Sbjct: 11836 KVSFQAANA----KSAANLKVKE--LPLIFITPLSDVKVFEKDEAKFECEVS-REPKTYR 11888
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W K + + I+ +L I +Y A + +S +LI+ EG
Sbjct: 11889 WLKGTQEITGDDRIELIKDGTKHSLVIKSAAFEDEAKYIFEAEDQ----HTSGKLII-EG 11943
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
F PL V A ESA F ++ I+V W K+++ + + + +
Sbjct: 11944 IRLKFLT-PLKDVTAKERESAVFTVELSHDN-IRVRWFKNDQRLHTSKFVSMDDEGKTHS 12001
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE-TVEETEGNSFR 902
+T + DT Q A+ S A+L + E P FT KL + T E E +
Sbjct: 12002 ITFRNLSIDDTSQIKVEAMGL----SSEAKLTVLEG--DPYFTGKLQDYTGVEKEEVILQ 12055
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
E A + V W+K+ EI P+ N I +L +KK D G YTC D
Sbjct: 12056 CEISKADAP---VKWFKDGQEIKPSKNAVIKADGKKRMLILKKPLKSDIGQYTC----DC 12108
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G+ + + I++ + V + L V V E E + + + I W G +
Sbjct: 12109 GTDKTSGKLNIEDREIKLV--RPLYSVEVMETETARFETEI-SEDDIHANWKLKGEALLQ 12165
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ C T L + G +A+NV S + K
Sbjct: 12166 TPECEIKEEGKTHFLILHNCRLDQTGGVDFQAANVKSSAHLRVKPRV------------- 12212
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+ + + I V TATF ++ + IP + +GK +L ++ + +G
Sbjct: 12213 -----IGLLRPLKDITVTAGETATFDCELSYEDIPVEWYLRGK--KLEPSDKVVMRSEGR 12265
Query: 1623 EAKLEIRDTTKTDSGLYRCVA 1685
L +RD D+G + VA
Sbjct: 12266 VHTLTLRDVKLEDAGEVQLVA 12286
Score = 72.0 bits (175), Expect = 2e-12
Identities = 92/413 (22%), Positives = 156/413 (37%), Gaps = 32/413 (7%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ V G + ++G P V+W + L AT + ++ ++V + G
Sbjct: 16551 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERALPQEATIETTAISS--SMVIKNCQRSHQG 16608
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y A+N+ GE + + V DV VG+P + + S ++
Sbjct: 16609 VYSLLAKNAAGERKKTIIVDVL-------------DVPGPVGIPFLAHNLTNDS--CKLT 16653
Query: 366 WFKD----GRPLKD-------------GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTAT 494
WF G P+ + P T N + Q F + A
Sbjct: 16654 WFSPEDDGGSPITNYVIEKREADHRAWTPVTYTVTRHNATVQGLIQGKAYF---FRIAAE 16710
Query: 495 NPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIK------VAW 656
N IG R+P +P P D V E +T P + +
Sbjct: 16711 NSIGMGPFVETTDALVIRDP--ITVPERPEDLEVKEVTKESVTLTWNPPKYDGGSDIINY 16768
Query: 657 AKDNREIRSGGNYQISYLEN--SAHLTILKVDKGDTGQYTCYAVNEVGKDS---CTAQLN 821
++R I + ++++ +N S T+ + +GDT +Y AVN VG+ CT +
Sbjct: 16769 VLESRLIGTEKFHKVTS-DNLMSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPIT 16827
Query: 822 IKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFK 1001
K+ L PP+ + + G +F L GR +G V+W+K+ ++ I
Sbjct: 16828 CKDELAPPTLDLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTT 16887
Query: 1002 NNALLLQVKKASMGDAGLYTCKVSNDAGS--ALCTSSIVIK--EPKKPPVFDQ 1148
L L+ KA D+G Y+ V N GS +C ++V + P P +FD+
Sbjct: 16888 PTTLALEKLKAKRSDSGKYSVVVENSTGSRKGVCQVNVVDRPGPPVGPVIFDE 16940
Score = 69.3 bits (168), Expect = 1e-11
Identities = 108/437 (24%), Positives = 161/437 (36%), Gaps = 26/437 (5%)
Frame = +3
Query: 165 VDSNDSGEYICRAENSVG---------EVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLP 317
+D N E+ A+N VG + L E L S R+L V+ G P
Sbjct: 18584 LDENQEYEFRVCAQNQVGIGRPAELKDAIKPKEILEPPEIDLDASM-RKLVTVR--AGCP 18640
Query: 318 VVFECAVSGSEPISVSWFKDG--RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTA 491
+ V G V+W K G ++ G Q +D +A L I + R +G+YS T
Sbjct: 18641 IRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDLVDTMAFLVIPNSTRDDSGKYSLTL 18697
Query: 492 TNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVT--------GTQPIK 647
NP G + N D P D V + CH++ G+Q
Sbjct: 18698 VNPAGEKAVFV--------NVRVLDTPGPVSDLKVSDVTKTSCHISWAPPENDGGSQVTH 18749
Query: 648 VAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCT---AQL 818
K E ++ + S H+T L G + AVNE G T +
Sbjct: 18750 YIVEKREAERKTWATVTPEVKKTSFHVTNLV--PGTEYFFRVTAVNEYGPGVPTDVPKPV 18807
Query: 819 NIKERLIPPSFTKKLSETVEETEGNSFR--LEGRVAGSQPISVAWYKNNVEIHPTANCEI 992
+ L P +KL E E T+ ++ L G I E P
Sbjct: 18808 LATDPLSEPDPPRKL-EVTEMTKNSAVLAWLPPLRDGGAKIDGYIVSYREEEQPADRWTE 18866
Query: 993 TFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP--VT 1166
L L V G + N G +L + + E K+ + + L P +T
Sbjct: 18867 YSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQIT 18926
Query: 1167 VSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDY 1346
+ G+ L++ HV G +W K ++ S + A ++VL KDVT+ D+G Y
Sbjct: 18927 IKAGKKLRIEAHVYGKPNPVCKWKKGEDDVVTSSHLAVHKAENSSVLIIKDVTRKDSGYY 18986
Query: 1347 VCKASNVAGSDTSKSKV 1397
A N +G+DT K KV
Sbjct: 18987 SLTAENSSGTDTQKIKV 19003
Score = 67.4 bits (163), Expect = 4e-11
Identities = 111/498 (22%), Positives = 185/498 (37%), Gaps = 43/498 (8%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V VG ++ ++G P+ ++W K D L+ T + ++ L + +D G Y
Sbjct: 23258 VQVGQDLKIEVPISGRPKPTITWTKDDLPLKQTTRINVTDSLDLTVLSIKETHKDDGGHY 23317
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
N VG+ ++S + ++ PP PV F+ +E I++SW
Sbjct: 23318 GITVANVVGQKTASIEIITLDKPDPPKG-------------PVKFDEV--SAESITLSWE 23362
Query: 372 KDGRPLKDGPNIQTSFL--DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
PL G T+++ T +++ + + + T + + + I E
Sbjct: 23363 P---PLYTGGCQITNYVVQKRDTTTTVWEVVSATVARTTLKVTK-LKTGTEYQFRIFAEN 23418
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDN------REIRSGGNYQISY 707
R F + P+ V + E GT P A +KD+ I +GG+ I Y
Sbjct: 23419 RYGQSFALESEPI---VAQYPYKEPGPPGT-PFVTAVSKDSMVVQWHEPINNGGSPVIGY 23474
Query: 708 -LENSAHLTIL-----------------KVDKGDTGQYTCYAVNEVG------------- 794
LE +IL +++G ++ YA N VG
Sbjct: 23475 HLEKKERNSILWTKVNKTIIHDTQFKAVNLEEGIEYEFRVYAENIVGIGKASKNSECYVA 23534
Query: 795 KDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS----FRLEGRVAGSQPISVAWYKNNV 962
+D C E +I L T +G S + +E R A + N +
Sbjct: 23535 RDPCDPP-GTPEAIIVKRHEITLQWTKPAYDGGSVITGYIVEKRDLPEGRWMKASFTNVI 23593
Query: 963 EIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVF 1142
E T + + + K A AG + K S+ G + + P F
Sbjct: 23594 ETQFTVSGLTEDQRYEFRVIAKNA----AGAVS-KPSDSTGPITARDEVELPRISMDPKF 23648
Query: 1143 DQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDV 1322
+ V+ GE +L V G I+WL+ +EI+ S R + A+L KD
Sbjct: 23649 RD---TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARYEIKNTDFKALLIVKDA 23705
Query: 1323 TKADAGDYVCKASNVAGS 1376
+ D G Y+ +ASNVAGS
Sbjct: 23706 IRIDGGQYILRASNVAGS 23723
Score = 67.0 bits (162), Expect = 6e-11
Identities = 50/195 (25%), Positives = 87/195 (44%), Gaps = 2/195 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V +G++A L CQ+ G P + W++ +L + YKM TL + D G
Sbjct: 30559 VTTKLGEAAQLSCQIVGRPLPDIKWFRFGKELVQSRKYKMSSDGRTHTLTVMTEEQEDEG 30618
Query: 186 EYICRAENSVGEVSSSTFLTVQ-EQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
Y C A N VGEV SS+ L +Q + P + + VG + G ++
Sbjct: 30619 VYTCVATNEVGEVESSSKLLLQATPQFHPGYPLK-EKYYGAVGSTLRIHVMYIGRPVPAI 30677
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDR-SFAGQYSCTATNPIGSASSSARLILT 539
+WF+ + L++ NI ++ L + R + AG+Y +N +G+ + ++
Sbjct: 30678 TWFRGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVLGTVDT---MLDV 30734
Query: 540 EGRNPPFFDIPLAPV 584
E ++ P D P P+
Sbjct: 30735 EIQDKP--DKPTGPI 30747
Score = 66.6 bits (161), Expect = 8e-11
Identities = 126/618 (20%), Positives = 228/618 (36%), Gaps = 39/618 (6%)
Frame = +3
Query: 3 PVKVTVGD----SASLQCQL----AGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVF 158
P KVT+ D SASL + G+ +G Y + + + T + + + V + V
Sbjct: 24233 PGKVTLTDVSQTSASLMWEKPEHDGGSRILG---YVVEMQPKGTEKWSVVAESKVCSAVV 24289
Query: 159 NQVDSNDSGEYICRAENSVGEVSSSTF---LTVQEQKLPPSFSRQLRDVQETVGLPVVFE 329
+ S + +A N G+ + ++ + PSF G + E
Sbjct: 24290 TGLSSGQEYHFRVKAYNEKGQSDPRVLGVPVIAKDLTIQPSFKLPFNTYSVQAGEDLKIE 24349
Query: 330 CAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGS 509
V G +SW KDG PLK + L+I ++++ G+Y+ TATN G+
Sbjct: 24350 IPVIGRPRPEISWVKDGEPLKQTTRVNVEKTATSTILHIKESNKDDFGKYTVTATNSAGT 24409
Query: 510 ASSSARLILTEGRNPPFFDIPLAPVDA-VVGESADFECHVTGTQPIKVAWAKDNREIRSG 686
A+ + +I+ E PP + V A V S + + G Q + + R+ +
Sbjct: 24410 ATENLSIIILEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISN--YIVEKRDTTTT 24467
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLI--------P 842
+ +S + I K+ G Q+ +A N GK +A L+ K ++ P
Sbjct: 24468 TWHMVSATVARTTIKITKLKMGSEYQFRIFAENRYGK---SAPLDSKPVIVQYPFKEPGP 24524
Query: 843 PSFTKKLSETVEE---------TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEIT 995
P S + ++ +G S + + + S+ W V+++ T +
Sbjct: 24525 PGTPFVTSVSKDQMLVQWHEPVNDGGSKVIGYHLEQKEKNSILW----VKLNKTPIQDTK 24580
Query: 996 FKNNALLLQVKKASMGDAGL-YTCKVSND-----AGSALCTSSIVIKEPKKPPVFDQHLT 1157
FK L D GL Y +VS + ++ + V ++P PP + +
Sbjct: 24581 FKTTGL----------DEGLEYEFRVSAENIVGIGKASKVSECFVARDPCDPPGRPEAIV 24630
Query: 1158 PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEF--KDVTKA 1331
+ + + GS +I ++ P R + EF + +
Sbjct: 24631 ITRNNVTLKWKKPAYDGGS---KITGYIVEKKDLPDGRWMKASFTNVLDTEFTVSGLVED 24687
Query: 1332 DAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTA 1511
++ A N AG+ + S+ T +D K V +V
Sbjct: 24688 QRYEFRVIARNAAGNFSEPSESTGAITARDEIDAPNASLDPKYKDV-------IVVHAGE 24740
Query: 1512 TFI--AKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVA 1685
TF+ A + G PIP++ W+K R+ I L ++D ++D G Y
Sbjct: 24741 TFVLEADIRGKPIPDIVWSKDGRELEETAARMEIKSTIQRTTLVVKDCIRSDGGQYILKL 24800
Query: 1686 FNKHGEIESNVNLQVNER 1739
N G + ++V +R
Sbjct: 24801 SNVGGTKTIPITVKVLDR 24818
Score = 63.2 bits (152), Expect = 8e-10
Identities = 55/201 (27%), Positives = 80/201 (39%), Gaps = 2/201 (0%)
Frame = +3
Query: 1134 PVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS--DRCSFSFANGTAVL 1307
P F Q L V V EG H+ G + W + G+ I S SF++G A L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 1308 EFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSI 1487
VTKA++G Y +A+N +G TS +++ F QS+
Sbjct: 66 TIPAVTKANSGRYSLRATNGSGQATSTAELLVTAETAPPN------------FTQRLQSM 113
Query: 1488 RVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSG 1667
V + + +V G P P VK+ + ++ I Q+G+ L I + DSG
Sbjct: 114 TVRQGSQVRLQVRVTGIPTPVVKFYR-DGAEIQSSLDFQISQEGELYSLLIAEAYPEDSG 172
Query: 1668 LYRCVAFNKHGEIESNVNLQV 1730
Y A N G S L V
Sbjct: 173 TYSVNATNSVGRATSTAELLV 193
Score = 63.2 bits (152), Expect = 8e-10
Identities = 110/511 (21%), Positives = 193/511 (37%), Gaps = 56/511 (10%)
Frame = +3
Query: 36 LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSV 215
L+ + G P VSW KG+ L + TLV +D+G+Y +N
Sbjct: 20019 LKIPIKGKPVPSVSWKKGEDPLATDTRVSVESSAVNTTLVVYDCRKSDAGKYTITLKNVA 20078
Query: 216 GEVSSS-TFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLK 392
G + T V + +P P+ FE + E +++ W G P
Sbjct: 20079 GTKEGTLTIKVVGKPGIPTG--------------PIKFEEVTA--EAVTLKW---GPPKD 20119
Query: 393 DGPNIQTSFL----DNV-------------ATLNIFQTDRSFAGQYSCTATNP--IGSAS 515
DG + T+++ D+V T + + + +A N +G
Sbjct: 20120 DGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVMRLHEGMEYTFRVSAENKYGVGEGL 20179
Query: 516 SSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNY 695
S ++ R+P FD+P AP + + +T T P K + Y
Sbjct: 20180 KSEPIV---ARHP--FDVPDAPPPPNIVDVRHDSVSLTWTDPRKTGGSPIT-------GY 20227
Query: 696 QISYLENSAHL--------------TILKVDKGDTGQYTCYAVN--EVGKDSCTAQLNIK 827
I + E ++ L + + +G ++ A+N VGK S ++ +
Sbjct: 20228 HIEFKERNSLLWKRANKTPIRMKDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVA 20287
Query: 828 -ERLIPPSFTKKLSET--------VEETEGNSFRLEGRVAGSQPI-SVAWYKNNVEIHPT 977
+ + PP + +S T E +L G + + + S +W K N P
Sbjct: 20288 LDPIDPPGKPEVISVTRNSVTLVWTEPKYDGGHKLTGYIVEKRELPSKSWTKANHVNVPD 20347
Query: 978 ANCEITFKNNALLLQVKKASMGDAGLYTCKV--SNDAGSALC----TSSIVIKEPKKPP- 1136
+T + + G Y +V N AG+ T +I+ K+ + P
Sbjct: 20348 CAFTVT-------------DLVEGGKYEFRVRAKNTAGAISAPSESTDTIICKDEYEAPT 20394
Query: 1137 -VFDQHLTP-VTVSEGEFLQLSC-HVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVL 1307
V D + +TV G+ + LS + G + W KAG++I+PSD + ++++
Sbjct: 20395 IVLDPTIKDGLTVKAGDTIILSAISILGKPLPKSSWSKAGKDIRPSDIVQITSTPTSSMI 20454
Query: 1308 EFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
K T+ DAG+Y A+N G+ + KVT
Sbjct: 20455 AVKYATRKDAGEYTITATNPFGTKSEHVKVT 20485
Score = 63.2 bits (152), Expect = 8e-10
Identities = 86/399 (21%), Positives = 147/399 (36%), Gaps = 20/399 (5%)
Frame = +3
Query: 48 LAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVS 227
+ G P V W + + A+ + ++ L+ V+ DSG+YI ENS G S
Sbjct: 21901 IKGRPAPEVKWTREHGESLDKASIES--TSSYTLLIIGNVNRFDSGKYILTIENSSGSKS 21958
Query: 228 SSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNI 407
+ + V + PP + + +V L GS+ + K K +
Sbjct: 21959 AFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWEPPLIDGGSKINNYIVEKRESTRKAYSTV 22018
Query: 408 QTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVD 587
T+ ++ Q S+ + IG + +A + R P I L V
Sbjct: 22019 TTNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLVDVT 22078
Query: 588 AVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS---------------- 719
+ ++W K + GG+ + Y+
Sbjct: 22079 R---------------NSVSLSWEKPEHD---GGSRILGYIVEMQSKGSDKWVTCATVKV 22120
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI----KERLIPPSFTKKLSETVEETE 887
TI + +G+ + A NE G S QL++ K+ +IPP+F K L T
Sbjct: 22121 TEATITGLIQGEEYSFRVSAQNEKGI-SDPRQLSVPVIAKDLVIPPAF-KLLFTTFTVLA 22178
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
G +++ G +V W+K++V + T N LL +K+A D G Y K
Sbjct: 22179 GEDLKVDVPFTGRPTPAVTWHKDDVPLKQTTRVNAESTENNSLLTIKEACREDVGHYIVK 22238
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEF 1184
++N AG A T ++++ + PP + VT F
Sbjct: 22239 LTNSAGEATETLNVIVLDKPGPPTGPVKMEEVTADSVTF 22277
Score = 61.2 bits (147), Expect = 3e-09
Identities = 91/416 (21%), Positives = 157/416 (37%), Gaps = 22/416 (5%)
Frame = +3
Query: 201 AENSVGEVSSSTF---LTVQEQKLPPSF---SRQLRDVQETVGLPVVFECAVSGSEPISV 362
A N+ GE + + V+++ PP + R+ VG + + G V
Sbjct: 17208 AVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIRVGDTLRLSAIIKGVPFPKV 17267
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+ R I + + + L I G YS T NP GS + S ++++
Sbjct: 17268 TWKKEDRAAPTKARIDVTPVGS--KLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLV-- 17323
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIK------VAWAKDNREIRSGGNYQIS 704
D P P D V E C++T +P+ + + +++ S +S
Sbjct: 17324 ------LDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERKDVASTEWSPLS 17377
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKD---SCTAQLNIKERLIPPSFTKKLSET- 872
+++G+ + A N+ G+ + + L PP K L
Sbjct: 17378 TTSKKKSHLAKHLNEGNQYVFRVAAENQYGRGPFVETPKPIKAVDPLHPPGPPKNLHHVD 17437
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKN-NALLLQVKKASMGDA 1049
V++TE + + G PI+ + E P I FK L V G
Sbjct: 17438 VDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTPDW---IKFKTVTNLACVVTGLQQGKT 17494
Query: 1050 GLYTCKVSNDAGSALCTSSIVIKEPKK--PPVFD---QHLTPVTVSEGEFLQLSCHVRGS 1214
+ K N G L ++I I+ +K PP + + + + V G ++ +RG
Sbjct: 17495 YRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGV 17554
Query: 1215 EPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
+W G EIK + + N ++VL K+ + D G+Y SN AG+ T
Sbjct: 17555 PIPTAKWTTDGNEIKTDEHYTVETDNFSSVLTIKNCLRKDTGEYQITVSNAAGTKT 17610
Score = 60.1 bits (144), Expect = 7e-09
Identities = 101/489 (20%), Positives = 171/489 (34%), Gaps = 23/489 (4%)
Frame = +3
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
G +VSW KDG+ LK+ + S V +L I + R G Y +N GS +
Sbjct: 25437 GRPQATVSWKKDGQTLKETTRVNVSSSKTVTSLIIKEASREDVGTYELCVSNSAGSVTVP 25496
Query: 522 ARLILTEGRNPPF-FDIPLAPVDAVV----GESADFECHVTGTQPIKVAWAKDNREIRSG 686
+I+ + PP I D + D C ++ + + RE S
Sbjct: 25497 ITVIVLDKPGPPGPIHIDEVSCDNITISWNPPEYDGGCQISN-------YIVEKRETTST 25549
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLI-----PPSF 851
+ +S + I+++ G Q+ A N GK S + + PP
Sbjct: 25550 TWHVVSQAVARTSIKIVRLVTGSEYQFRVCAENRFGKSSYSESSAVVAEYPFSPPGPPGT 25609
Query: 852 TKKLSET---------VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKN 1004
K + T V +G S L + + S+ W K N + +++ +
Sbjct: 25610 PKVVHATKSTMLVTWQVPVNDGGSRVLGYHLEYKERSSILWSKANKTLIADTQMKVSGLD 25669
Query: 1005 NALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS---IVIKEPKKPPVFDQHLTPVTVSE 1175
L+ + Y N AG C+ S + ++P PP +T +T
Sbjct: 25670 EGLMYE-----------YHVYAENIAGIGKCSKSCEPVPARDPCDPP-GQPEVTNITRKS 25717
Query: 1176 GEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFAN-GTAVLEFKDVTKADAGDYVC 1352
H G I ++ RE+ +F N E ++T+ ++
Sbjct: 25718 VSLKWSKPHYDGGAKI-TGYIIERRELPDGRWLKCNFTNVPETYFEVTELTEDQRYEFRV 25776
Query: 1353 KASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVG 1532
A N A S + S+ T +D K V ++ V++ A V
Sbjct: 25777 FARNAADSISEPSESTGPITVKDDVEAPRIMMDVKFRDVIVVKAGEVLK-----INADVA 25831
Query: 1533 GDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIES 1712
G P+P + W K ++ + R I L ++D + DSG Y N G
Sbjct: 25832 GRPLPIISWAK-DGVEIEERARTEIVSTDYTTLLTVKDCVRRDSGQYVLTVKNVAGTRSM 25890
Query: 1713 NVNLQVNER 1739
VN +V ++
Sbjct: 25891 AVNCKVLDK 25899
Score = 58.9 bits (141), Expect = 2e-08
Identities = 87/375 (23%), Positives = 140/375 (37%), Gaps = 21/375 (5%)
Frame = +3
Query: 336 VSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
+ G V W ++ D +I+++ + L I +R +G+Y T N GS S
Sbjct: 21901 IKGRPAPEVKWTREHGESLDKASIEST--SSYTLLIIGNVNRFDSGKYILTIENSSGSKS 21958
Query: 516 SSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI---RSG 686
+ N D P P D V E +T P+ +K N I R
Sbjct: 21959 AFV--------NVRVLDTPGPPQDLKVKEVTKTSVTLTWEPPLIDGGSKINNYIVEKRES 22010
Query: 687 GNYQISYLENSAHLTILKVDKGDTG---QYTCYAVNE--VGKDSCTAQ-LNIKERLIPPS 848
S + + H T KVD+ G + A NE +G + TA+ + ER +PP
Sbjct: 22011 TRKAYSTVTTNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPG 22070
Query: 849 F---------TKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFK 1001
+ LS E +G S R+ G + Q K + + A ++T
Sbjct: 22071 KITLVDVTRNSVSLSWEKPEHDGGS-RILGYIVEMQS------KGSDKWVTCATVKVTEA 22123
Query: 1002 NNALLLQVKKASMGDAGLYTCKVSNDAGSA---LCTSSIVIKEPKKPPVFDQHLTPVTVS 1172
L+Q G+ + N+ G + + ++ K+ PP F T TV
Sbjct: 22124 TITGLIQ------GEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFTTFTVL 22177
Query: 1173 EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVC 1352
GE L++ G + W K +K + R + ++L K+ + D G Y+
Sbjct: 22178 AGEDLKVDVPFTGRPTPAVTWHKDDVPLKQTTRVNAESTENNSLLTIKEACREDVGHYIV 22237
Query: 1353 KASNVAGSDTSKSKV 1397
K +N AG T V
Sbjct: 22238 KLTNSAGEATETLNV 22252
Score = 58.2 bits (139), Expect = 3e-08
Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Frame = +3
Query: 240 LTVQEQKLPPSFS-----RQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPN 404
+T+ + +PP + L V+ G V + V G +VSW KDG LK
Sbjct: 19301 VTIMAESVPPRIELSVAMKSLLTVK--AGTNVCLDATVFGKPKPTVSWKKDGTLLKPSEG 19358
Query: 405 IQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
I+ + N+ TL +F R +G Y+ TA NP GS S++ +L + + PP
Sbjct: 19359 IKMAMKRNLCTLELFSVTRKDSGDYTITAENPSGSKSATIKLKVLDKPGPP 19409
Score = 57.8 bits (138), Expect = 4e-08
Identities = 76/356 (21%), Positives = 129/356 (36%), Gaps = 10/356 (2%)
Frame = +3
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W ++ D +Q N L+I DR+ AG+Y N GS S+ + +
Sbjct: 24073 ITWSREEGEFTD--KVQIEKAANYTQLSIDNCDRNDAGKYVLKLENSSGSKSAFVTVKV- 24129
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAK------DNREIRSGGNYQI 701
D P P + V E + P+ AK D RE +
Sbjct: 24130 -------LDTPGPPQNLAVKEVRKDSVLLVWDPPLIDGGAKVKNYVIDKRESTRKAYANV 24182
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET-VE 878
S + L + + +G + A NE G ++ + PPS K++ T V
Sbjct: 24183 SNKCSKTSLKVENLTEGAIYYFRVMAENEFGIGVPVETVDAVKASEPPSPPGKVTLTDVS 24242
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
+T + + G I Y ++ T + ++ V S G +
Sbjct: 24243 QTSASLMWEKPEHDGGSRI--LGYVVEMQPKGTEKWSVVAESKVCSAVVTGLSSGQEYHF 24300
Query: 1059 TCKVSNDAGSA---LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRI 1229
K N+ G + + ++ K+ P F +V GE L++ V G I
Sbjct: 24301 RVKAYNEKGQSDPRVLGVPVIAKDLTIQPSFKLPFNTYSVQAGEDLKIEIPVIGRPRPEI 24360
Query: 1230 QWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
W+K G +K + R + + +L K+ K D G Y A+N AG+ T +
Sbjct: 24361 SWVKDGEPLKQTTRVNVEKTATSTILHIKESNKDDFGKYTVTATNSAGTATENLSI 24416
Score = 57.4 bits (137), Expect = 5e-08
Identities = 71/292 (24%), Positives = 107/292 (36%), Gaps = 3/292 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VT D A CQL+ + V WY+ +++ YK ++ L+ +D EY
Sbjct: 12851 VTEFDDAVFSCQLS-REKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEY 12909
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C V + S L V+E +P R +D+ E G VVF A + + V W
Sbjct: 12910 AC----GVDDRKSRARLFVEE--IPVEIIRPPQDILEAPGADVVF-LAELNKDKVEVQWL 12962
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K+ + G Q + L I G+Y A + AR L
Sbjct: 12963 KNNMIIVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKD------KEARAKLELAAA 13016
Query: 552 PPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P I A D VV G+ + W K+N + S +
Sbjct: 13017 PK---IKTADQDLVVDVGQPLTMVVPYDAFPKAEAEWFKENEPLSSK---TVDTTAEQTS 13070
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP-PSFTKKLSETVE 878
ILK K D G+Y N+ GK +N+K +P P +++ET +
Sbjct: 13071 FRILKAKKEDKGRYKVVLQNKHGK--AEGFINLKVIDVPGPVRNLEVTETFD 13120
Score = 56.6 bits (135), Expect = 8e-08
Identities = 61/240 (25%), Positives = 91/240 (37%), Gaps = 16/240 (6%)
Frame = +3
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLP--------PSFSRQLRDVQETVGLPVVFECAVS 341
E+ + EN GE S + + E P P F +LR++ C V+
Sbjct: 30913 EFRVKCENLGGE---SEWSEISEPVTPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVT 30969
Query: 342 GSEPISVSWFKDGRPL-KDGPNIQTS-FLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
G V W++ G+ + DG + F L I A Y ATN GS S
Sbjct: 30970 GHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVS 31029
Query: 516 SSARLILTEGRNPPFFDIP-----LAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIR 680
+A L E P +P + V A+ GE + +G + W K I
Sbjct: 31030 GTASL---EVEVPAKIHLPKNLEGMGAVHALRGEVISIKIPFSGKPDPVITWQKGQDLID 31086
Query: 681 SGGNYQISYLENSAHLTILK-VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK 857
+ G+YQ+ + L V++ D G Y A N G D T +L++ + PP K
Sbjct: 31087 NNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVK 31146
Score = 55.5 bits (132), Expect = 2e-07
Identities = 31/87 (35%), Positives = 44/87 (50%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G + L + G P+ VSW K T L+P+ KM + N+ TL V DSG+Y
Sbjct: 19324 VKAGTNVCLDATVFGKPKPTVSWKKDGTLLKPSEGIKMAMKRNLCTLELFSVTRKDSGDY 19383
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPS 272
AEN G S++ L V ++ PP+
Sbjct: 19384 TITAENPSGSKSATIKLKVLDKPGPPA 19410
Score = 54.3 bits (129), Expect = 4e-07
Identities = 98/467 (20%), Positives = 180/467 (38%), Gaps = 40/467 (8%)
Frame = +3
Query: 117 YKMHFRNNVATLVFNQVDSNDSGEYICRAE----NSVGEVSSSTFLTVQEQKLPPSFSRQ 284
Y++H + F D +Y R + E S ST ++L
Sbjct: 29406 YRVHTNATIRNNEFTVTDLKMGQKYSFRVAAVNVKGMSEYSESTAEIEPVERLEIPDLEL 29465
Query: 285 LRDVQETV----GLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQ 452
D+++TV G + +VSG P ++W K G L I T+ ++ + L + +
Sbjct: 29466 ADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKKGIDLASRAIIDTT--ESYSLLIVDK 29523
Query: 453 TDRSFAGQYSCTATNPIG--SASSSARLILTEGRNPPF-------------FDIPL---- 575
+R AG+Y+ A N G SA+ ++ T G P +++P
Sbjct: 29524 VNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEVPTIDGG 29583
Query: 576 APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA--HLTILKVDK 749
APV+ + E + + K K ++ + Y+IS L A + +L +
Sbjct: 29584 APVNNYIIEKRE-----AAMRAFKTVTTKCSKTL-----YRISGLIEGAMYYFRVLPENI 29633
Query: 750 GDTGQ----YTCYAVNEVGKDSCTAQL-NIKERLIPPSFTKKLSETVEETEGNSFRLEGR 914
G+ V+EV ++ ++ + + ++ K L + G + LE
Sbjct: 29634 YGIGEPCETSDAVLVSEVPLVPTKLEVVDVTKSTVTLAWEKPLYDGGSRLTG--YVLEAC 29691
Query: 915 VAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSAL 1094
AG++ W K +T K L V + G+ L+ + N+ G +
Sbjct: 29692 RAGTE----RWMK-----------VVTLKPTVLEHTVISLNEGEQYLFRVRAQNEKGVSE 29736
Query: 1095 ---CTSSIVIKEPKKPPVFDQHLTP---VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
+++ +++ + P D P + V G ++L + G P W AG ++
Sbjct: 29737 PREIVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKL 29796
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
+ S+R + A L ++ T D GDYV + NV G+ + KV
Sbjct: 29797 RESERVTVETHTKVAKLTIRETTIKDTGDYVLELKNVTGTTSETIKV 29843
Score = 53.9 bits (128), Expect = 5e-07
Identities = 61/288 (21%), Positives = 103/288 (35%), Gaps = 1/288 (0%)
Frame = +3
Query: 267 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNI 446
P + ++R + G F V V W+ +G L++ I + V TL I
Sbjct: 32398 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 32457
Query: 447 FQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHV 626
+G Y TN G AS A L +T G + D V S E +
Sbjct: 32458 LDCHIDDSGTYRAVCTNYKGEASDYATLDVTGG---DYTTYASQRRDEQVPRSVFPE--L 32512
Query: 627 TGTQPIKVAWAKDNREIRSGGNY-QISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDS 803
T T+ V+ K E+ + + ++ L ++ + + + A+ E +
Sbjct: 32513 TRTEAYAVSSFKKTSEMEASSSVREMKSLMTETRESLSSYEHHASAEMKSAAIEEKSLEE 32572
Query: 804 CTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTAN 983
+ IK L TK S TV EG S R G +V W + I +A
Sbjct: 32573 KSTHRKIKTTLAARILTKPRSITV--YEGESARFSCDTDGEPVPTVTWLRGGQVISTSAR 32630
Query: 984 CEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPK 1127
++T ++ D G Y+ V N G ++ +++ +
Sbjct: 32631 HQVTTSKYKSTFEISSVQASDEGNYSVVVENSDGRQEAQFTLTVQKAR 32678
Score = 53.5 bits (127), Expect = 7e-07
Identities = 32/100 (32%), Positives = 46/100 (46%)
Frame = +3
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ ++V K+P P D + V EGE L + R + W K G+E+K SDR +
Sbjct: 14392 SENVVAKDPDCRPTIDLETHDIVVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 14451
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
+ +A LE +ADAG Y N GS T+ V
Sbjct: 14452 MKNDHISAHLEVPKSVRADAGIYTVTLENKLGSATASINV 14491
Score = 52.8 bits (125), Expect = 1e-06
Identities = 62/273 (22%), Positives = 109/273 (39%), Gaps = 23/273 (8%)
Frame = +3
Query: 474 QYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVA 653
Q+ A N G +S S +P F + ++PVD + D+ VT + I +
Sbjct: 27845 QFRVFAENSAGLSSPS---------DPSKFTLAVSPVDPP--GTPDY-IDVT-RETITLK 27891
Query: 654 WAKDNREIRSGGNYQISYL-----------------ENSAHLTILKVDKGDTGQYTCYAV 782
W N +R GG+ ++Y + T+ + GD ++ A
Sbjct: 27892 W---NPPLRDGGSKIVAYSIEKRQGSDRWTRCNFTDVSECQYTVTGLSPGDRYEFRIIAR 27948
Query: 783 NEVGKDSCTAQ----LNIKERLIPPS--FTKKLSETVEETEGNSFRLEGRVAGSQPISVA 944
N VG S +Q + ++ + P+ F + + + G S R++ V G V
Sbjct: 27949 NAVGTISPPSQSSGVIMTRDENVAPTVEFGPEYFDGITIKSGESLRIKALVQGRPVPRVT 28008
Query: 945 WYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEP 1124
W+K+ VEI N EIT + L V+ A+ G+Y + N +GS ++ +++
Sbjct: 28009 WFKDGVEIEKKMNMEITDVLGSTSLFVRDATRDHRGVYRVEAKNASGSTKAEITVRVQDT 28068
Query: 1125 KKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
PV T +T + + H G P+
Sbjct: 28069 PGKPVGPIRFTNITGEKMTLWWDAPHNDGCAPV 28101
Score = 51.6 bits (122), Expect = 3e-06
Identities = 34/110 (30%), Positives = 50/110 (45%)
Frame = +3
Query: 846 SFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQV 1025
S K +T+ G +FRLE V G ++ W + + EI +A EI + LL V
Sbjct: 23643 SMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARYEIKNTDFKALLIV 23702
Query: 1026 KKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSE 1175
K A D G Y + SN AGS ++ + + PP +T VT +
Sbjct: 23703 KDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTAEK 23752
Score = 51.6 bits (122), Expect = 3e-06
Identities = 50/236 (21%), Positives = 92/236 (38%), Gaps = 16/236 (6%)
Frame = +3
Query: 165 VDSNDSGEYI--CRAENSVGEVSSS---TFLTVQEQKLPPSFSRQL---RDVQETVGLPV 320
+ N+ +Y+ RA+N G T +TVQ+ ++ P+ + + G PV
Sbjct: 29714 ISLNEGEQYLFRVRAQNEKGVSEPREIVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPV 29773
Query: 321 VFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNP 500
++G P + SWF G L++ + VA L I +T G Y N
Sbjct: 29774 ELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIKDTGDYVLELKNV 29833
Query: 501 IGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIR 680
G+ S + ++I+ + PP I + +DA + + G P+ + + R+
Sbjct: 29834 TGTTSETIKVIVLDKPGPPSGPIKVDEIDATSVTISWGPPELDGGAPLS-GYVVEQRDAH 29892
Query: 681 SGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDS--------CTAQLNI 824
G +S + ++ +G+ + A N G S C + +NI
Sbjct: 29893 RPGWLPVSESVTRSTFKFTRLIEGNEYVFRVAATNRFGIGSYLQSEVIECRSSINI 29948
Score = 50.8 bits (120), Expect = 4e-06
Identities = 82/374 (21%), Positives = 132/374 (35%), Gaps = 41/374 (10%)
Frame = +3
Query: 138 NVAT---LVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV 308
NV T L+ D G Y+ A NS G F+ +V +
Sbjct: 15171 NVGTKSELIIKNALRKDHGRYVITATNSCGS----------------KFAAARVEVFDVP 15214
Query: 309 GLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNI------FQTDRSFA 470
G + + V+ + ++W P DG + T F+ + +T+RS
Sbjct: 15215 GPVLDLKPVVTNRKMCLLNW---SDPEDDGGSEITGFIIERKDAKMHTWRQPIETERS-- 15269
Query: 471 GQYSCTATNPIGSASSSARLILTE--GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPI 644
C T + R+I G PP P+ VD + G E +T T+
Sbjct: 15270 ---KCDITGLLEGQEYMFRVIAKNKFGCGPPVEIGPILAVDPL-GPPTSPE-RLTYTERT 15324
Query: 645 KVAWAKDNREIRSGGNYQIS--YLENSAH-----------------LTILKVDKGDTGQY 767
K D +E RS G I +E H + +D+ ++
Sbjct: 15325 KSTITLDWKEPRSNGGCPIQGYIIEKRRHDKPDFERVNKHLCPTTSFLVEDLDEHQMYEF 15384
Query: 768 TCYAVNEVGKDSCTAQLN--IKERLIPPSFTKKLS---ETVEETEGNSFRLEGRVAGSQP 932
AVNE+G+ + LN I++ +PP+ +LS +T++ G + V G
Sbjct: 15385 RVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVNIPADVTGLPM 15444
Query: 933 ISVAWYKNNVEIHPTANC------EITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSAL 1094
+ W KN I + E++ L + KA+ D G YT SN GS
Sbjct: 15445 PKIEWSKNETVIEKPTDALKITKEEVSRSEAKTELSIPKATREDKGTYTVTASNRLGSVF 15504
Query: 1095 CTSSIVIKEPKKPP 1136
+ + + PP
Sbjct: 15505 RNVHVEVYDRPSPP 15518
Score = 50.8 bits (120), Expect = 4e-06
Identities = 75/378 (19%), Positives = 128/378 (33%), Gaps = 31/378 (8%)
Frame = +3
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
G P +V+W KD + L D+ + L I Q R G+Y T N +G SS
Sbjct: 27314 GRPPPTVTWRKDEKNLGSDARYSIQNTDSSSILTIPQVTRHDTGKYILTIENGVGQPKSS 27373
Query: 522 ARLI----------------LTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVA 653
+ +++G F+D PL + G PI +
Sbjct: 27374 TVSVKVLDTPAACQNLQVKHVSQGTVTLFWDPPL----------------IDGGSPI-IN 27416
Query: 654 WAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVG-KDSCTAQLNIKE 830
+ + ++ +S+ +S + + + + +AVNE+G + C +K
Sbjct: 27417 YIIEKKDATKRTWSSVSHKCSSTSFKVTDLSEKTPFFFRVFAVNEIGIGEPCETTEPVKA 27476
Query: 831 RLIPPSF-----------TKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPT 977
+P + LS T + +G S + V W ++ I T
Sbjct: 27477 AEVPAPIRDLSVKDSTKTSVTLSWTKPDFDGGSVITDYIVERKGKGEQTW--SHAGISKT 27534
Query: 978 ANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT 1157
E+ L+ + ++ + GL ++ + +KE PP D
Sbjct: 27535 CEIEVGKLKELSELEFRVSARNEKGL---------SDSVSIGPVTVKELVIPPEVDLSEI 27585
Query: 1158 P---VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTK 1328
P V V G + L +G I WLK G +K S+ L K+ K
Sbjct: 27586 PGAQVAVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESELVRLGKTENKLTLSIKNAKK 27645
Query: 1329 ADAGDYVCKASNVAGSDT 1382
+ G Y N +T
Sbjct: 27646 ENGGKYTIILDNAVCRNT 27663
>ref|XP_002703630.1| PREDICTED: titin [Bos taurus].
Length = 33452
Score = 1240 bits (3208), Expect = 0.0
Identities = 614/656 (93%), Positives = 629/656 (95%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PVKVTVGDSASLQCQL GTPEI VSW+KGDTKLRPTATYKMHFRNN+ATLVFNQVDSNDS
Sbjct: 7952 PVKVTVGDSASLQCQLGGTPEIAVSWFKGDTKLRPTATYKMHFRNNIATLVFNQVDSNDS 8011
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV
Sbjct: 8012 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 8071
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SWFKDGRP+KD PNIQ SFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE
Sbjct: 8072 SWFKDGRPVKDSPNIQASFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 8131
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
G+NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA
Sbjct: 8132 GKNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 8191
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
HLTILKVDKGD+GQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF+
Sbjct: 8192 HLTILKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFK 8251
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LEGRVAGSQPISVAWYKNN+EIHPT+NCEITFKNN LLLQ+K+A M DAGLYTCKVSNDA
Sbjct: 8252 LEGRVAGSQPISVAWYKNNIEIHPTSNCEITFKNNTLLLQIKRAGMDDAGLYTCKVSNDA 8311
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GSALCTSSIVIKEPKKPPVFDQHLTPVT SEGEF+QLSCHV GSEPIRIQWLKAGREIKP
Sbjct: 8312 GSALCTSSIVIKEPKKPPVFDQHLTPVTASEGEFVQLSCHVWGSEPIRIQWLKAGREIKP 8371
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
SDRCSFSFANGTAVLE KDVTKADAGDYVCKASNVAGSDTSKSKVT
Sbjct: 8372 SDRCSFSFANGTAVLELKDVTKADAGDYVCKASNVAGSDTSKSKVTIKDKPAAVPAAKKA 8431
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRI IHQKGD
Sbjct: 8432 AVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRILIHQKGD 8491
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLK 1802
EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV+ERKKQEKIEGDLRAMLKKTPVLK
Sbjct: 8492 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPVLK 8551
Query: 1803 KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEEETHRL 1970
KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFE+LKQ++ EETHRL
Sbjct: 8552 KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQTEGEETHRL 8607
Score = 506 bits (1304), Expect = e-143
Identities = 259/578 (44%), Positives = 359/578 (62%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++ +VGDS SLQCQ+AG+PEI VSWYKGDTKLRPT Y+ +F NNVATLVFN+V+ NDS
Sbjct: 6070 PLEASVGDSVSLQCQVAGSPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDS 6129
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+AENS+G SS T +QE++LPPSF+RQL+D+++TVGLPV C ++GS PI V
Sbjct: 6130 GEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQV 6189
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SW++DG L+D N+QTSF+DNVATL I QTD S +GQYSC+A+NP+G+ASSSARL E
Sbjct: 6190 SWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTARE 6249
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ PFFDI +D + GESADFECHVTG QP+++ W+KDN+EIR GGNY I+ + N+
Sbjct: 6250 PKKSPFFDIKPVSIDIIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTP 6309
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
HL ILKV KGD+GQYTC A N+VGKD C+AQL++KE PP F KKL + +G S
Sbjct: 6310 HLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE---PPKFVKKLEASKVAKQGESIH 6366
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE +++GS I V+W++N+ E+H + ++F ++ +L + +AS D+G Y C+ N
Sbjct: 6367 LECKISGSPEIKVSWFRNDSELHESWKYNMSFVDSVAVLTINEASAEDSGDYICEAHNGV 6426
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G A C++++ I K PPVF Q +P+ +G + C + G+ P + W+K ++++
Sbjct: 6427 GDASCSTALTI---KAPPVFTQKPSPIGALKGSDVVFQCEISGTPPFEVVWVKDRKQVRS 6483
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + N A L ++ AD G+Y CKA+N GSDT +
Sbjct: 6484 SKKFKITSKNFDASLHILNLEAADVGEYYCKATNEVGSDTCVCTLKFKEPPR-------- 6535
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
FV + + A V G +V W K K + + I +
Sbjct: 6536 -------FVKKLSDTSTLVGDAVELRAVVEGFQPISVVWLKDKGDVIRESENTRISFVDN 6588
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L++ +DSG Y C N G E + L V E
Sbjct: 6589 VATLQLGSPEASDSGKYVCQIKNDAGMRECSAILTVLE 6626
Score = 493 bits (1268), Expect = e-139
Identities = 252/577 (43%), Positives = 351/577 (60%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ +G+ +LQC++ GTPEI +SWYK TKLR YKM F+NNVA+LV N+VD +D G
Sbjct: 7012 VEAVIGEPITLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVG 7071
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY C+AEN VG V+SS+ L ++E+KLPPSF+R+L+DVQET+G PV FEC ++GSEP+ VS
Sbjct: 7072 EYTCKAENIVGAVASSSVLVIKERKLPPSFARKLKDVQETLGFPVAFECRINGSEPLQVS 7131
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+KDG LKD N+QTSF+ NVATL I QTD+S GQY+C+A+NP+G+ASSSA+L+L E
Sbjct: 7132 WYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLVLLEH 7191
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PPFFD+ VD +GES F+CHVTGT P+K+ WAKDNREIR GGNY+++ +EN+A
Sbjct: 7192 EVPPFFDLKPVSVDLALGESGSFKCHVTGTAPMKITWAKDNREIRPGGNYKMTLVENTAT 7251
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
LT+LK+ KGD GQYTCYA N GKDSC+A L ++E PP F KKL + + S R
Sbjct: 7252 LTVLKIGKGDAGQYTCYASNVAGKDSCSAHLGVQE---PPRFIKKLEPSRIVKQDESTRY 7308
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ GS I V WYK EI ++ ++F ++ +L++ S+ D+G YTC+ N AG
Sbjct: 7309 ECKIGGSPEIKVLWYKGETEIQESSKFRMSFVDSVAVLEMHGLSVEDSGDYTCEACNAAG 7368
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
SA T+S+ +KE PP+F + PV +G + L C ++G+ P ++ W K RE++
Sbjct: 7369 SASSTTSLKVKE---PPIFRKKPHPVETLKGADVHLECELQGTPPFQVSWHKDKRELRSG 7425
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ N + V AD G+Y CKA+N GSDT +T
Sbjct: 7426 KKYKIMSENFLTSIHILSVDAADVGEYQCKATNDVGSDTCVGSITLKAPPR--------- 7476
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FV +P + + A V G +V W K K + + I+I +
Sbjct: 7477 ------FVKKPSDVSTIVGEEVQLQATVEGAEPISVVWFKDKGEIVRESDNIWISYSENT 7530
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L+ ++G Y C N G E + + + E
Sbjct: 7531 ATLQFSRAETANAGKYTCQIKNDAGMQECSATVSILE 7567
Score = 326 bits (835), Expect = 5e-89
Identities = 195/582 (33%), Positives = 286/582 (49%), Gaps = 3/582 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ VT GD+ +L+C + GTPE+ W+K +L YK+ F N V+ L V +DSG
Sbjct: 7578 ITVTTGDTCTLECSVTGTPELTTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSG 7637
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y +N VG+ S + + V ++ +PPSF+R+L++ G VV EC V GS PISVS
Sbjct: 7638 VYSFEVQNPVGKDSCTASVQVSDRIVPPSFTRRLKETNGLSGSSVVMECKVYGSPPISVS 7697
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WF + + G QT+ DN L + + S AG Y+C ATN GS SA L +
Sbjct: 7698 WFHERNEISSGRKYQTTLTDNTCALTVNMLEESDAGNYTCIATNVAGSDECSAPLTV--- 7754
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
R PP F P+D + G + F V GT P V+W K + E+ G +S ++ A
Sbjct: 7755 REPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSTELVPGDTCNVSLEDSVAE 7814
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + VD +G+YTC NE GK SCT L +K P F KKL++ E +G L
Sbjct: 7815 LELFDVDTSQSGEYTCIVTNEAGKVSCTTHLYVK---APARFVKKLNDYSIE-KGKPLIL 7870
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
EG G+ PISV W KN + + P+ C IT + +L++ +++ DAG Y C + N +G
Sbjct: 7871 EGTYTGTPPISVTWKKNGINVTPSQRCNITTTERSAILEIPSSTVEDAGQYNCYIENTSG 7930
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
C++ I+I E PP F + L PV V+ G+ L C + G+ I + W K +++P+
Sbjct: 7931 KDSCSAQILILE---PPYFVRQLEPVKVTVGDSASLQCQLGGTPEIAVSWFKGDTKLRPT 7987
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
F N A L F V D+G+Y+C+A N G +S + +T
Sbjct: 7988 ATYKMHFRNNIATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLT--------------- 8032
Query: 1446 VDGKLFFVSEPQSIRVVEKTT---ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
V + S + +R V++T F V G +V W K R + I
Sbjct: 8033 VQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFK-DGRPVKDSPNIQASFL 8091
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
+ A L I T ++ +G Y C A N G S+ L + E K
Sbjct: 8092 DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGK 8133
Score = 319 bits (818), Expect = 5e-87
Identities = 189/573 (32%), Positives = 286/573 (49%), Gaps = 1/573 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G+S L+C+++G+PEI VSW++ D++L + Y M F ++VA L N+ + DSG+YIC
Sbjct: 6362 GESIHLECKISGSPEIKVSWFRNDSELHESWKYNMSFVDSVAVLTINEASAEDSGDYICE 6421
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A N VG+ S ST LT+ K PP F+++ + G VVF+C +SG+ P V W KD
Sbjct: 6422 AHNGVGDASCSTALTI---KAPPVFTQKPSPIGALKGSDVVFQCEISGTPPFEVVWVKDR 6478
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ ++ + + + A+L+I + + G+Y C ATN +GS + L E PP
Sbjct: 6479 KQVRSSKKFKITSKNFDASLHILNLEAADVGEYYCKATNEVGSDTCVCTLKFKE---PPR 6535
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE-IRSGGNYQISYLENSAHLTIL 737
F L+ +VG++ + V G QPI V W KD + IR N +IS+++N A L +
Sbjct: 6536 FVKKLSDTSTLVGDAVELRAVVEGFQPISVVWLKDKGDVIRESENTRISFVDNVATLQLG 6595
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+ D+G+Y C N+ G C+A L + E P+ + E + T GN+F LE V
Sbjct: 6596 SPEASDSGKYVCQIKNDAGMRECSAILTVLE----PARIIEKPEPMTVTTGNAFALECVV 6651
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
G+ +S W+K+ EI + ITF N L++ A M D GLY+ +V N G + C
Sbjct: 6652 TGTPELSAKWFKDGREIAADSKHHITFVNKVASLKIPCAEMSDKGLYSFEVKNSVGKSTC 6711
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
T S+ + + P F + L + G + L C V GS PI + W + G EI +C
Sbjct: 6712 TVSVHVSDRIVAPSFIRKLKDINAIVGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQ 6771
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF+ L + +D G Y C A+NVAGSD + +T +
Sbjct: 6772 SSFSENVCTLNLSFLEPSDTGTYTCVAANVAGSDECSAVLT---------------IQEP 6816
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F P S+ V+ T+ TF + + G P VKW KG R+L G I + +LE
Sbjct: 6817 PSFEQTPDSVEVLPGTSLTFTSVIRGTPPFKVKWFKGS-RELVSGESCSISLEDFVTELE 6875
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ + SG Y C+ N G +L V E
Sbjct: 6876 LFEVEPLQSGDYSCLVTNDAGSASCTAHLFVKE 6908
Score = 319 bits (817), Expect = 7e-87
Identities = 190/581 (32%), Positives = 285/581 (49%), Gaps = 3/581 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VTVG++ +L+C++AGTPE+ V WYK L + +K F N +++L V+ D+G Y
Sbjct: 5698 VTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVEKQDAGTY 5757
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
+ +N+VG+ S + + V ++ +PPSF+R+L+D +G + EC V+GS PISV+WF
Sbjct: 5758 TFQVQNNVGKSSCTAVVDVSDRMVPPSFTRRLKDTIGVLGTSCILECKVAGSSPISVAWF 5817
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
+ G QT+F DNV TL + D S G Y+C A N GS A L + E
Sbjct: 5818 HGKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANVAGSDECRAVLAVQE--- 5874
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP F P++ + G++ F + GT P KV W + RE+ G I + + A L
Sbjct: 5875 PPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGARELVKGDRCNIYFEDTVAELE 5934
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
+ VD +G+YTC N G+ SCT +L +KE P F KKLS+ E G S LE
Sbjct: 5935 LFNVDISQSGEYTCVVSNNAGQTSCTTRLFVKE---PAVFVKKLSDHSVE-PGKSIILES 5990
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
G+ PISV W K+ I P+ C I +L++ ++ DAG Y+C++ N+AG
Sbjct: 5991 TYKGTLPISVTWKKDGFNITPSEKCSIVTTEKTCILEILNSTKRDAGRYSCEIENEAGRD 6050
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
+C + + E PP F L P+ S G+ + L C V GS I + W K +++P+
Sbjct: 6051 VCEALVSTLE---PPYFVTELEPLEASVGDSVSLQCQVAGSPEITVSWYKGDTKLRPTPE 6107
Query: 1272 CSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVD 1451
F N A L F V D+G+Y CKA N G+ +SK+ +
Sbjct: 6108 YRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKT---------------VFRIQ 6152
Query: 1452 GKLFFVSEPQSIRVVEKTT---ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+ S + ++ +E+T T ++ G V W + L + +
Sbjct: 6153 ERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVSWYR-DGVLLRDDENLQTSFVDN 6211
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
A L+I T + SG Y C A N G S+ L E KK
Sbjct: 6212 VATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKK 6252
Score = 310 bits (793), Expect = 4e-84
Identities = 197/585 (33%), Positives = 278/585 (47%), Gaps = 12/585 (2%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G L+ GTP I V+W K + P+ + A L D+G+Y C
Sbjct: 7865 GKPLILEGTYTGTPPISVTWKKNGINVTPSQRCNITTTERSAILEIPSSTVEDAGQYNCY 7924
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
EN+ G+ S S + + E PP F RQL V+ TVG +C + G+ I+VSWFK
Sbjct: 7925 IENTSGKDSCSAQILILE---PPYFVRQLEPVKVTVGDSASLQCQLGGTPEIAVSWFKGD 7981
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
L+ + F +N+ATL Q D + +G+Y C A N +G SSS L + E + PP
Sbjct: 7982 TKLRPTATYKMHFRNNIATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPS 8041
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L V VG FEC V+G++PI V+W KD R ++ N Q S+L+N A L I +
Sbjct: 8042 FSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPVKDSPNIQASFLDNVATLNIFQ 8101
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
D+ GQY+C A N +G S +A+L + E PP F L+ V+ G S E V
Sbjct: 8102 TDRSFAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIPLA-PVDAVVGESADFECHVT 8160
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+QPI VAW K+N EI N +I++ N+ L + K GD+G YTC N+ G CT
Sbjct: 8161 GTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDSGQYTCYAVNEVGKDSCT 8220
Query: 1101 SSIVIKEPKKPPVFDQHLT-PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ + IKE PP F + L+ V +EG +L V GS+PI + W K EI P+ C
Sbjct: 8221 AQLNIKERLIPPSFTKKLSETVEETEGNSFKLEGRVAGSQPISVAWYKNNIEIHPTSNCE 8280
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
+F N T +L+ K DAG Y CK SN AGS S +
Sbjct: 8281 ITFKNNTLLLQIKRAGMDDAGLYTCKVSNDAGSALCTSSIV------------------- 8321
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKV-----------GGDPIPNVKWTKGKWRQLNQGGRIF 1604
+ EP+ V ++ A G +PI ++W K R++ R
Sbjct: 8322 ---IKEPKKPPVFDQHLTPVTASEGEFVQLSCHVWGSEPI-RIQWLKA-GREIKPSDRCS 8376
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
A LE++D TK D+G Y C A N G S + + ++
Sbjct: 8377 FSFANGTAVLELKDVTKADAGDYVCKASNVAGSDTSKSKVTIKDK 8421
Score = 309 bits (792), Expect = 5e-84
Identities = 189/585 (32%), Positives = 292/585 (49%), Gaps = 5/585 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ VT G++ +L+C + GTPE+ W+K ++ + + + F N VA+L + +D
Sbjct: 6636 PMTVTTGNAFALECVVTGTPELSAKWFKDGREIAADSKHHITFVNKVASLKIPCAEMSDK 6695
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y +NSVG+ + + + V ++ + PSF R+L+D+ VG VV EC VSGS PISV
Sbjct: 6696 GLYSFEVKNSVGKSTCTVSVHVSDRIVAPSFIRKLKDINAIVGASVVLECRVSGSAPISV 6755
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WF+DG + GP Q+SF +NV TLN+ + S G Y+C A N GS SA L + E
Sbjct: 6756 GWFQDGNEIVSGPKCQSSFSENVCTLNLSFLEPSDTGTYTCVAANVAGSDECSAVLTIQE 6815
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F+ V+ + G S F + GT P KV W K +RE+ SG + IS +
Sbjct: 6816 ---PPSFEQTPDSVEVLPGTSLTFTSVIRGTPPFKVKWFKGSRELVSGESCSISLEDFVT 6872
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + +V+ +G Y+C N+ G SCTA L +KE P +F K+L++ ET G+
Sbjct: 6873 ELELFEVEPLQSGDYSCLVTNDAGSASCTAHLFVKE---PATFVKRLADFSVET-GSPIV 6928
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE G+ PISV+W KN + + NC IT + +L++ +++ D Y+C + N+A
Sbjct: 6929 LEATFTGTPPISVSWMKNEFALTQSQNCSITMTEKSTILEILDSTIEDYAQYSCLIENEA 6988
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G +C + + + E PP F + L V GE + L C V G+ IRI W K +++
Sbjct: 6989 GQDICDAVVSVLE---PPYFIEPLEHVEAVIGEPITLQCKVDGTPEIRISWYKEHTKLRS 7045
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ F N A L V +D G+Y CKA N+ G+ S S +
Sbjct: 7046 APAYKMQFKNNVASLVINKVDHSDVGEYTCKAENIVGAVASSSVLV-------------- 7091
Query: 1443 XVDGKLFFVSEPQSIRVVEKT---TATFIAKVGGDPIPNVKWTKGKWRQLNQGG--RIFI 1607
+ + S + ++ V++T F ++ G V W K + F+
Sbjct: 7092 -IKERKLPPSFARKLKDVQETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFV 7150
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
H + A L+I T ++ G Y C A N G S+ L + E +
Sbjct: 7151 H---NVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLVLLEHE 7192
Score = 309 bits (792), Expect = 5e-84
Identities = 184/581 (31%), Positives = 286/581 (49%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ V G + + + GTP VSW+KG T+L P T + ++VA L VD++ S
Sbjct: 7766 PMDVLTGTNVTFTSIVKGTPPFSVSWFKGSTELVPGDTCNVSLEDSVAELELFDVDTSQS 7825
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C N G+VS +T L V K P F ++L D G P++ E +G+ PISV
Sbjct: 7826 GEYTCIVTNEAGKVSCTTHLYV---KAPARFVKKLNDYSIEKGKPLILEGTYTGTPPISV 7882
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+G + + + A L I + AGQY+C N G S SA++++ E
Sbjct: 7883 TWKKNGINVTPSQRCNITTTERSAILEIPSSTVEDAGQYNCYIENTSGKDSCSAQILILE 7942
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP+F L PV VG+SA +C + GT I V+W K + ++R Y++ + N A
Sbjct: 7943 ---PPYFVRQLEPVKVTVGDSASLQCQLGGTPEIAVSWFKGDTKLRPTATYKMHFRNNIA 7999
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L +VD D+G+Y C A N VG+ S + L ++E+ +PPSF+++L + V+ET G
Sbjct: 8000 TLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRD-VQETVGLPVV 8058
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
E V+GS+PISV+W+K+ + + N + +F +N L + + AG Y+C +N
Sbjct: 8059 FECAVSGSEPISVSWFKDGRPVKDSPNIQASFLDNVATLNIFQTDRSFAGQYSCTATNPI 8118
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GSA ++ +++ E K PP FD L PV GE CHV G++PI++ W K REI+
Sbjct: 8119 GSASSSARLILTEGKNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRS 8178
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S+ +A L V K D+G Y C A N G D+ +++
Sbjct: 8179 GGNYQISYLENSAHLTILKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPS----- 8233
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
F +++ E + +V G +V W K +++ I K +
Sbjct: 8234 ------FTKKLSETVEETEGNSFKLEGRVAGSQPISVAWYKNN-IEIHPTSNCEITFKNN 8286
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
L+I+ D+GLY C N G ++ + E KK
Sbjct: 8287 TLLLQIKRAGMDDAGLYTCKVSNDAGSALCTSSIVIKEPKK 8327
Score = 307 bits (787), Expect = 2e-83
Identities = 191/607 (31%), Positives = 287/607 (47%), Gaps = 1/607 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT D +L+C +AGTPE+ V W K ++ P+ + M F NNVA+ V DSG
Sbjct: 5133 VDVTERDPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSG 5192
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY + EN G S +L V +Q +PPSF+++L + + +G + EC VSGS PIS
Sbjct: 5193 EYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQ 5252
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKDG+ + + +N +L++ + Y+C +N G A+ S L + E
Sbjct: 5253 WFKDGKEISTSAKYRLVCHENTVSLDVNNLELEDTANYTCRVSNVAGDAACSGILTVKE- 5311
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F + A+ + +F+ + GT P K+ W KD+ E+ SG I +++
Sbjct: 5312 --PPSFLVKPERQQAIPDSTVEFKAVLKGTPPFKIKWFKDDVELASGPKCFIGLEGSTSF 5369
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + VD TGQYTC N+VG DSCT L + E PP F KKL T G+S RL
Sbjct: 5370 LNLYSVDASKTGQYTCQVTNDVGSDSCTTTLLVTE---PPKFVKKLEATKIVKAGDSARL 5426
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ GS I V WY+N E+ + + F ++ +LQ+ D G + C+ N AG
Sbjct: 5427 ECKITGSPDIRVVWYRNEHELPASDKYRMAFIDSVAVLQMNYLGTEDTGDFICEAQNPAG 5486
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
S C++ +++KE PPVF V + + + C + G+ P + W K R+++ S
Sbjct: 5487 STSCSTKVIVKE---PPVFSSFPPVVETLKNAEVSIECELSGTPPFEVVWYKDKRQLRSS 5543
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + N A + +V D G+Y CKA N GSDT V
Sbjct: 5544 KKYKIASKNFHASIHILNVDTLDIGEYHCKAQNEVGSDTCICIVKLKEPPR--------- 5594
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FVS+ S+ VV A A + G +V+W K K + + I I +
Sbjct: 5595 ------FVSKLNSLTVVAGEPAELQASIEGTQPISVQWLKEKEEVVRESENIRITFVENV 5648
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLK- 1802
A L+ ++G Y C N G E+ L V E + G + + +T L+
Sbjct: 5649 ATLQFSKAEPANAGKYICQIKNDGGMRENMATLTVLEPAVIVEKAGSMTVTVGETCTLEC 5708
Query: 1803 KGAGEEE 1823
K AG E
Sbjct: 5709 KVAGTPE 5715
Score = 302 bits (774), Expect = 6e-82
Identities = 183/574 (31%), Positives = 281/574 (48%), Gaps = 2/574 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G + +LQ + G+ I V+W KG ++ KM F N VA L+ V + +Y C
Sbjct: 3921 GQTVTLQAAVRGSEPISVTWMKGQEIIKEDGKIKMSFANGVAVLIIPDVQISFGDKYTCL 3980
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
AEN G +S L V+E P + +Q T G P E V+G+ + W+KDG
Sbjct: 3981 AENEAGSQTSVGELIVKE---PAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDG 4037
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
RPL + SF +NVA L + + +GQY+ +N +GS+S + + PF
Sbjct: 4038 RPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPF 4097
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F PL VD+VV + +C + G+ P++V+W KD +E+ S Y+I+++E +A L I +
Sbjct: 4098 FTKPLRNVDSVVSGTCRLDCKIAGSLPMRVSWFKDGKEVTSSDRYRIAFVEGTASLEISR 4157
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF-TKKLSETVEETEGNSFRLEGRV 917
VD D G +TC A N VG C+ L ++E PPSF TK S+ + G++ L+
Sbjct: 4158 VDMSDAGNFTCRATNSVGSKDCSGALIVQE---PPSFVTKPASKDI--LPGSAVFLKSTF 4212
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
GS P ++ W+K + E+ NC I + L++ D+G YTCKVSN AG+ C
Sbjct: 4213 QGSTPFTIRWFKGDKELVSGGNCYINKEALESSLELYSVKTTDSGTYTCKVSNVAGAVEC 4272
Query: 1098 TSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRC 1274
++++ +KE P F + L + +G+ QL+C V G+ PI+I W REIK S +
Sbjct: 4273 SANLFVKE---PATFVERLELSQXLKKGDTTQLACKVTGTPPIKITWFANDREIKESSKH 4329
Query: 1275 SFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDG 1454
SF TAVL D+ D+G+Y+C+A N AGSD S V
Sbjct: 4330 KMSFVESTAVLRLTDIAVEDSGEYMCEAQNEAGSDHCSS---------------ILIVKE 4374
Query: 1455 KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKL 1634
+F E + I V+++ +A+V G P + W K L G + + L
Sbjct: 4375 SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDN-TTLRSGRKYKTFIQDRLVSL 4433
Query: 1635 EIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+I D G Y+C N+ G + + + E
Sbjct: 4434 QILKFVAADVGKYQCRVTNEVGSSTCSARVTLRE 4467
Score = 301 bits (772), Expect = 1e-81
Identities = 188/576 (32%), Positives = 274/576 (47%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
+G S L+C++AG+ I V+W+ G TK+ A Y+ F +NV TL N +DS+D G Y C
Sbjct: 5796 LGTSCILECKVAGSSPISVAWFHGKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGSYTC 5855
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKD 377
A N G L VQE PPSF ++ ++ G + F + G+ P V WF+
Sbjct: 5856 VAANVAGSDECRAVLAVQE---PPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRG 5912
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
R L G F D VA L +F D S +G+Y+C +N G S + RL + E P
Sbjct: 5913 ARELVKGDRCNIYFEDTVAELELFNVDISQSGEYTCVVSNNAGQTSCTTRLFVKE---PA 5969
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F L+ G+S E GT PI V W KD I I E + L IL
Sbjct: 5970 VFVKKLSDHSVEPGKSIILESTYKGTLPISVTWKKDGFNITPSEKCSIVTTEKTCILEIL 6029
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
K D G+Y+C NE G+D C A ++ E PP F +L E +E + G+S L+ +V
Sbjct: 6030 NSTKRDAGRYSCEIENEAGRDVCEALVSTLE---PPYFVTEL-EPLEASVGDSVSLQCQV 6085
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
AGS I+V+WYK + ++ PT F NN L K ++ D+G YTCK N G+A
Sbjct: 6086 AGSPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASS 6145
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ I+E + PP F + L + + G + L+C + GS PI++ W + G ++ +
Sbjct: 6146 KTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVSWYRDGVLLRDDENLQ 6205
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF + A L+ + +G Y C ASN G+ +S +++T
Sbjct: 6206 TSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSP----------- 6254
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
FF +P SI ++ +A F V G + W+K +++ GG I G+ L
Sbjct: 6255 -FFDIKPVSIDIIAGESADFECHVTGAQPMRITWSKDN-KEIRPGGNYTITCVGNTPHLR 6312
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
I K DSG Y C A N G+ + L V E K
Sbjct: 6313 ILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPK 6348
Score = 297 bits (761), Expect = 2e-80
Identities = 186/579 (32%), Positives = 275/579 (47%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+ G L+C+L GTP VSW+K +LR YK+ N + ++ VD+ D
Sbjct: 7390 PVETLKGADVHLECELQGTPPFQVSWHKDKRELRSGKKYKIMSENFLTSIHILSVDAADV 7449
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+A N VG + +T+ K PP F ++ DV VG V + V G+EPISV
Sbjct: 7450 GEYQCKATNDVGSDTCVGSITL---KAPPRFVKKPSDVSTIVGEEVQLQATVEGAEPISV 7506
Query: 363 SWFKD-GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
WFKD G +++ NI S+ +N ATL + + + AG+Y+C N G SA + +
Sbjct: 7507 VWFKDKGEIVRESDNIWISYSENTATLQFSRAETANAGKYTCQIKNDAGMQECSATVSIL 7566
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E P + G++ EC VTGT + W KD +E+ S Y+IS+
Sbjct: 7567 E---PAAIVEKPESITVTTGDTCTLECSVTGTPELTTKWFKDGKELTSDNKYKISFFNKV 7623
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
+ L I+ V D+G Y+ N VGKDSCTA + + +R++PPSFT++L ET G+S
Sbjct: 7624 SGLKIINVAPSDSGVYSFEVQNPVGKDSCTASVQVSDRIVPPSFTRRLKET-NGLSGSSV 7682
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
+E +V GS PISV+W+ EI + T +N L V DAG YTC +N
Sbjct: 7683 VMECKVYGSPPISVSWFHERNEISSGRKYQTTLTDNTCALTVNMLEESDAGNYTCIATNV 7742
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS C++ + ++E PP F Q P+ V G + + V+G+ P + W K E+
Sbjct: 7743 AGSDECSAPLTVRE---PPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSTELV 7799
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
P D C+ S + A LE DV + +G+Y C +N AG + + +
Sbjct: 7800 PGDTCNVSLEDSVAELELFDVDTSQSGEYTCIVTNEAGKVSCTTHL-------------- 7845
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V FV + + + G P +V W K + R I
Sbjct: 7846 -YVKAPARFVKKLNDYSIEKGKPLILEGTYTGTPPISVTWKK-NGINVTPSQRCNITTTE 7903
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A LEI +T D+G Y C N G+ + + + E
Sbjct: 7904 RSAILEIPSSTVEDAGQYNCYIENTSGKDSCSAQILILE 7942
Score = 295 bits (754), Expect = 1e-79
Identities = 172/572 (30%), Positives = 285/572 (49%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
GD+ L C++ GTP I ++W+ D +++ ++ +KM F + A L + DSGEY+C
Sbjct: 4297 GDTTQLACKVTGTPPIKITWFANDREIKESSKHKMSFVESTAVLRLTDIAVEDSGEYMCE 4356
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A+N G S+ L V+E P F+++ + ++ V+ V+G+ P ++WFKD
Sbjct: 4357 AQNEAGSDHCSSILIVKES---PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDN 4413
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
L+ G +T D + +L I + + G+Y C TN +GS++ SAR+ L R PP
Sbjct: 4414 TTLRSGRKYKTFIQDRLVSLQILKFVAADVGKYQCRVTNEVGSSTCSARVTL---REPPT 4470
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F + ++ G +A F+ + G+ PI V W KDN EI N ++++ N A L +
Sbjct: 4471 FVKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDNEEITEDDNIRMTFENNVASLYLSG 4530
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
++ G+Y C A N+ G C A L++KE P+ + + +++ T+G+ L+ + +
Sbjct: 4531 IEVKHDGKYVCQAKNDAGIQRCFAVLSVKE----PATIIEEAVSIDVTQGDPATLQVKFS 4586
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G++ I+ W+K+ E+ +I+ + +L++ D+G YT +V ND G + C
Sbjct: 4587 GTKEITAKWFKDGQELTLGQKYKISVTDTVSILKIISTEKRDSGEYTFEVQNDVGRSSCK 4646
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSF 1280
+SI + + PP F + L + +G + L C V GS PI IQW K +EI S++ F
Sbjct: 4647 ASINVLDLIIPPSFTKKLKKMDSIKGSSIDLECIVAGSHPISIQWFKDDQEITASEKYKF 4706
Query: 1281 SFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKL 1460
SF + TA LE + +D+G Y C A+N AG + +T V
Sbjct: 4707 SFHDNTAFLEISQLEGSDSGTYTCSATNKAGHNQCSGHLT---------------VKEPP 4751
Query: 1461 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEI 1640
+F+ +PQS V T A VGG +KW K ++L+ G + + LE+
Sbjct: 4752 YFLEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDN-KELHSGAARSVWKDDTSTILEL 4810
Query: 1641 RDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
DSG Y C N G + +L V E
Sbjct: 4811 FSAKAADSGTYICQLSNDVGTATTKASLFVKE 4842
Score = 294 bits (752), Expect = 2e-79
Identities = 173/590 (29%), Positives = 284/590 (48%), Gaps = 1/590 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKL-RPTATYKMHFRNNVATLVFNQVDSNDS 182
V VG+ LQ + G I V W+K ++ R + + + N ATL F++ ++ ++
Sbjct: 7484 VSTIVGEEVQLQATVEGAEPISVVWFKDKGEIVRESDNIWISYSENTATLQFSRAETANA 7543
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y C+ +N G S +++ E P + + + T G EC+V+G+ ++
Sbjct: 7544 GKYTCQIKNDAGMQECSATVSILE---PAAIVEKPESITVTTGDTCTLECSVTGTPELTT 7600
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WFKDG+ L + SF + V+ L I S +G YS NP+G S +A + +++
Sbjct: 7601 KWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASVQVSD 7660
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F L + + G S EC V G+ PI V+W + EI SG YQ + +N+
Sbjct: 7661 RIVPPSFTRRLKETNGLSGSSVVMECKVYGSPPISVSWFHERNEISSGRKYQTTLTDNTC 7720
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
LT+ +++ D G YTC A N G D C+A L ++E PPSF +K + ++ G +
Sbjct: 7721 ALTVNMLEESDAGNYTCIATNVAGSDECSAPLTVRE---PPSFVQK-PDPMDVLTGTNVT 7776
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
V G+ P SV+W+K + E+ P C ++ +++ L++ +G YTC V+N+A
Sbjct: 7777 FTSIVKGTPPFSVSWFKGSTELVPGDTCNVSLEDSVAELELFDVDTSQSGEYTCIVTNEA 7836
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G CT+ + +K P + F + L ++ +G+ L L G+ PI + W K G + P
Sbjct: 7837 GKVSCTTHLYVKAPAR---FVKKLNDYSIEKGKPLILEGTYTGTPPISVTWKKNGINVTP 7893
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S RC+ + +A+LE T DAG Y C N +G D+ +++
Sbjct: 7894 SQRCNITTTERSAILEIPSSTVEDAGQYNCYIENTSGKDSCSAQILILEPP--------- 7944
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+FV + + ++V +A+ ++GG P V W KG +L +H + +
Sbjct: 7945 ------YFVRQLEPVKVTVGDSASLQCQLGGTPEIAVSWFKGD-TKLRPTATYKMHFRNN 7997
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLR 1772
A L DSG Y C A N GE+ S+ L V E+K LR
Sbjct: 7998 IATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR 8047
Score = 293 bits (750), Expect = 4e-79
Identities = 179/564 (31%), Positives = 268/564 (47%), Gaps = 1/564 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G L+ GTP I VSW K + L + + L D +Y
Sbjct: 6921 VETGSPIVLEATFTGTPPISVSWMKNEFALTQSQNCSITMTEKSTILEILDSTIEDYAQY 6980
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C EN G+ ++V E PP F L V+ +G P+ +C V G+ I +SW+
Sbjct: 6981 SCLIENEAGQDICDAVVSVLE---PPYFIEPLEHVEAVIGEPITLQCKVDGTPEIRISWY 7037
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K+ L+ P + F +NVA+L I + D S G+Y+C A N +G+ +SS+ L++ E +
Sbjct: 7038 KEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCKAENIVGAVASSSVLVIKERKL 7097
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP F L V +G FEC + G++P++V+W KD ++ N Q S++ N A L
Sbjct: 7098 PPSFARKLKDVQETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQ 7157
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
IL+ D+ GQY C A N +G S +A+L + E +PP F K +V+ G S +
Sbjct: 7158 ILQTDQSHVGQYNCSASNPLGTASSSAKLVLLEHEVPPFFDLK-PVSVDLALGESGSFKC 7216
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
V G+ P+ + W K+N EI P N ++T N L V K GDAG YTC SN AG
Sbjct: 7217 HVTGTAPMKITWAKDNREIRPGGNYKMTLVENTATLTVLKIGKGDAGQYTCYASNVAGKD 7276
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPV-TVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
C++ + ++E PP F + L P V + E + C + GS I++ W K EI+ S
Sbjct: 7277 SCSAHLGVQE---PPRFIKKLEPSRIVKQDESTRYECKIGGSPEIKVLWYKGETEIQESS 7333
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ SF + AVLE ++ D+GDY C+A N AGS +S + + V
Sbjct: 7334 KFRMSFVDSVAVLEMHGLSVEDSGDYTCEACNAAGSASSTTSL---------------KV 7378
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F +P + ++ ++ G P V W K K R+L G + I +
Sbjct: 7379 KEPPIFRKKPHPVETLKGADVHLECELQGTPPFQVSWHKDK-RELRSGKKYKIMSENFLT 7437
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHG 1700
+ I D G Y+C A N G
Sbjct: 7438 SIHILSVDAADVGEYQCKATNDVG 7461
Score = 291 bits (745), Expect = 1e-78
Identities = 198/665 (29%), Positives = 307/665 (46%), Gaps = 10/665 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ VT GD A+LQ + +GT EI W+K +L YK+ + V+ L + DSG
Sbjct: 4571 IDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGQKYKISVTDTVSILKIISTEKRDSG 4630
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY +N VG S + V + +PPSF+++L+ + G + EC V+GS PIS+
Sbjct: 4631 EYTFEVQNDVGRSSCKASINVLDLIIPPSFTKKLKKMDSIKGSSIDLECIVAGSHPISIQ 4690
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKD + + + SF DN A L I Q + S +G Y+C+ATN G S L + E
Sbjct: 4691 WFKDDQEITASEKYKFSFHDNTAFLEISQLEGSDSGTYTCSATNKAGHNQCSGHLTVKE- 4749
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP+F D + V GT P+ + W KDN+E+ SG + + S
Sbjct: 4750 --PPYFLEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTI 4807
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + D+G Y C N+VG + A L +KE PP F KK S + G S
Sbjct: 4808 LELFSAKAADSGTYICQLSNDVGTATTKASLFVKE---PPQFIKKPSPVLVLRNGQSTTF 4864
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ G+ I V+WY + EI I+F + Q+ A + ++G Y C+ NDAG
Sbjct: 4865 ECQITGTPEIRVSWYLDGNEITAVEKHGISFIDGLATFQISGARVENSGTYVCEAQNDAG 4924
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
+A C+ + +KE PP F + L PV V + ++L C V G+ P ++ WL+ +EI+ S
Sbjct: 4925 TASCSIELKVKE---PPTFIRELKPVEVVKDSDVELECEVMGTSPFQVTWLRNNKEIRSS 4981
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + + L +D GDY C SN GS + ++V+
Sbjct: 4982 KKYTLTDRVSVFNLNINRCDPSDTGDYQCIVSNEGGSCSCSARVSLKEPPS--------- 5032
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
F+ + ++I V K++ATF + V G P ++ W K + L++ + I +
Sbjct: 5033 ------FIKKIENITTVLKSSATFQSTVAGSPPISITWLKDD-QILDEDDNVHISFVNNV 5085
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE-------RKKQEKIEGD---LRA 1775
A L+IR SG Y C A N+ G L V E K + E D L
Sbjct: 5086 ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIIEKAKSVDVTERDPVTLEC 5145
Query: 1776 MLKKTPVLKKGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEE 1955
++ TP LK + ++ K + P Y + + FR +Q+ ++KQ E
Sbjct: 5146 VVAGTPELK--------VKWLKDGKQIVPSRYFSMSFENNVASFR--IQS--VMKQDSGE 5193
Query: 1956 ETHRL 1970
T ++
Sbjct: 5194 YTFKV 5198
Score = 290 bits (741), Expect = 4e-78
Identities = 177/576 (30%), Positives = 282/576 (48%), Gaps = 1/576 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V GDSA L+C++ G+P+I V WY+ + +L + Y+M F ++VA L N + + D+G++
Sbjct: 5418 VKAGDSARLECKITGSPDIRVVWYRNEHELPASDKYRMAFIDSVAVLQMNYLGTEDTGDF 5477
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
IC A+N G S ST + V+E PP FS V+ V EC +SG+ P V W+
Sbjct: 5478 ICEAQNPAGSTSCSTKVIVKE---PPVFSSFPPVVETLKNAEVSIECELSGTPPFEVVWY 5534
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KD R L+ + + + A+++I D G+Y C A N +GS + + + + +
Sbjct: 5535 KDKRQLRSSKKYKIASKNFHASIHILNVDTLDIGEYHCKAQNEVGSDTC---ICIVKLKE 5591
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI-RSGGNYQISYLENSAHL 728
PP F L + V GE A+ + + GTQPI V W K+ E+ R N +I+++EN A L
Sbjct: 5592 PPRFVSKLNSLTVVAGEPAELQASIEGTQPISVQWLKEKEEVVRESENIRITFVENVATL 5651
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
K + + G+Y C N+ G A L + E P+ + + ++ T G + LE
Sbjct: 5652 QFSKAEPANAGKYICQIKNDGGMRENMATLTVLE----PAVIVEKAGSMTVTVGETCTLE 5707
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+VAG+ +SV WYK+ + + + +F N L++ DAG YT +V N+ G
Sbjct: 5708 CKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVEKQDAGTYTFQVQNNVGK 5767
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
+ CT+ + + + PP F + L G L C V GS PI + W +I
Sbjct: 5768 SSCTAVVDVSDRMVPPSFTRRLKDTIGVLGTSCILECKVAGSSPISVAWFHGKTKIVSGA 5827
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ +F++ L+ + +D G Y C A+NVAGSD ++ + V
Sbjct: 5828 KYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANVAGSDECRAVLA---------------V 5872
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
FV EP+ + V+ TF + + G P V W +G R+L +G R I+ + A
Sbjct: 5873 QEPPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGA-RELVKGDRCNIYFEDTVA 5931
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+LE+ + + SG Y CV N G+ L V E
Sbjct: 5932 ELELFNVDISQSGEYTCVVSNNAGQTSCTTRLFVKE 5967
Score = 289 bits (740), Expect = 6e-78
Identities = 173/577 (29%), Positives = 278/577 (48%), Gaps = 1/577 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++V G + + + GTP V W++G +L ++F + VA L VD + S
Sbjct: 5884 PLEVLPGKNITFTSVIRGTPPFKVGWFRGARELVKGDRCNIYFEDTVAELELFNVDISQS 5943
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C N+ G+ S +T L V+E P F ++L D G ++ E G+ PISV
Sbjct: 5944 GEYTCVVSNNAGQTSCTTRLFVKE---PAVFVKKLSDHSVEPGKSIILESTYKGTLPISV 6000
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KDG + + L I + + AG+YSC N G A L
Sbjct: 6001 TWKKDGFNITPSEKCSIVTTEKTCILEILNSTKRDAGRYSCEIENEAGRDVCEA---LVS 6057
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP+F L P++A VG+S +C V G+ I V+W K + ++R Y+ + N A
Sbjct: 6058 TLEPPYFVTELEPLEASVGDSVSLQCQVAGSPEITVSWYKGDTKLRPTPEYRTYFTNNVA 6117
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L KV+ D+G+YTC A N +G S I+ER +PPSF ++L + +E+T G
Sbjct: 6118 TLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKD-IEQTVGLPVT 6176
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L R+ GS PI V+WY++ V + N + +F +N L++ + + +G Y+C SN
Sbjct: 6177 LTCRLNGSAPIQVSWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPL 6236
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G+A ++ + +EPKK P FD + + GE CHV G++P+RI W K +EI+P
Sbjct: 6237 GTASSSARLTAREPKKSPFFDIKPVSIDIIAGESADFECHVTGAQPMRITWSKDNKEIRP 6296
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ + T L V K D+G Y C+A+N G D ++++
Sbjct: 6297 GGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLS-------------- 6342
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFI-AKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V FV + ++ +V ++ + + K+ G P V W + +L++ + +
Sbjct: 6343 -VKEPPKFVKKLEASKVAKQGESIHLECKISGSPEIKVSWFRND-SELHESWKYNMSFVD 6400
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
A L I + + DSG Y C A N G+ + L +
Sbjct: 6401 SVAVLTINEASAEDSGDYICEAHNGVGDASCSTALTI 6437
Score = 286 bits (733), Expect = 4e-77
Identities = 179/578 (30%), Positives = 274/578 (47%), Gaps = 1/578 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKL-RPTATYKMHFRNNVATLVFNQVDSNDSGE 188
V G+ A LQ + GT I V W K ++ R + ++ F NVATL F++ + ++G+
Sbjct: 5604 VVAGEPAELQASIEGTQPISVQWLKEKEEVVRESENIRITFVENVATLQFSKAEPANAGK 5663
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
YIC+ +N G + LTV E P + + TVG EC V+G+ +SV W
Sbjct: 5664 YICQIKNDGGMRENMATLTVLE---PAVIVEKAGSMTVTVGETCTLECKVAGTPELSVEW 5720
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+KDG+ L + SF + +++L I ++ AG Y+ N +G +S +A + +++
Sbjct: 5721 YKDGKLLTSSQKHKFSFYNKISSLKILSVEKQDAGTYTFQVQNNVGKSSCTAVVDVSDRM 5780
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP F L V+G S EC V G+ PI VAW +I SG YQ ++ +N L
Sbjct: 5781 VPPSFTRRLKDTIGVLGTSCILECKVAGSSPISVAWFHGKTKIVSGAKYQTTFSDNVCTL 5840
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
+ +D D G YTC A N G D C A L ++E PPSF K+ E +E G +
Sbjct: 5841 QLNSLDSSDMGSYTCVAANVAGSDECRAVLAVQE---PPSFVKE-PEPLEVLPGKNITFT 5896
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+ G+ P V W++ E+ C I F++ L++ + +G YTC VSN+AG
Sbjct: 5897 SVIRGTPPFKVGWFRGARELVKGDRCNIYFEDTVAELELFNVDISQSGEYTCVVSNNAGQ 5956
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
CT+ + +KEP VF + L+ +V G+ + L +G+ PI + W K G I PS+
Sbjct: 5957 TSCTTRLFVKEPA---VFVKKLSDHSVEPGKSIILESTYKGTLPISVTWKKDGFNITPSE 6013
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+CS T +LE + TK DAG Y C+ N AG D ++ V+
Sbjct: 6014 KCSIVTTEKTCILEILNSTKRDAGRYSCEIENEAGRDVCEALVSTLEPP----------- 6062
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
+FV+E + + + + +V G P V W KG +L + + A
Sbjct: 6063 ----YFVTELEPLEASVGDSVSLQCQVAGSPEITVSWYKGD-TKLRPTPEYRTYFTNNVA 6117
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
L DSG Y C A N G S ++ ER+
Sbjct: 6118 TLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQ 6155
Score = 286 bits (733), Expect = 4e-77
Identities = 175/564 (31%), Positives = 272/564 (48%), Gaps = 1/564 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G S L+ GT I V+W K + P+ + L D+G Y
Sbjct: 5980 VEPGKSIILESTYKGTLPISVTWKKDGFNITPSEKCSIVTTEKTCILEILNSTKRDAGRY 6039
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C EN G ++ E PP F +L ++ +VG V +C V+GS I+VSW+
Sbjct: 6040 SCEIENEAGRDVCEALVSTLE---PPYFVTELEPLEASVGDSVSLQCQVAGSPEITVSWY 6096
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K L+ P +T F +NVATL + + + +G+Y+C A N IG+ASS + E +
Sbjct: 6097 KGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQL 6156
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP F L ++ VG C + G+ PI+V+W +D +R N Q S+++N A L
Sbjct: 6157 PPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVSWYRDGVLLRDDENLQTSFVDNVATLK 6216
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
IL+ D +GQY+C A N +G S +A+L +E P F K +++ G S E
Sbjct: 6217 ILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIK-PVSIDIIAGESADFEC 6275
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
V G+QP+ + W K+N EI P N IT N L++ K GD+G YTC+ +ND G
Sbjct: 6276 HVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKD 6335
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVS-EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
+C++ + +KE PP F + L V+ +GE + L C + GS I++ W + E+ S
Sbjct: 6336 MCSAQLSVKE---PPKFVKKLEASKVAKQGESIHLECKISGSPEIKVSWFRNDSELHESW 6392
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ + SF + AVL + + D+GDY+C+A N G + + +T +
Sbjct: 6393 KYNMSFVDSVAVLTINEASAEDSGDYICEAHNGVGDASCSTALT---------------I 6437
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F +P I ++ + F ++ G P V W K + +Q+ + I K +A
Sbjct: 6438 KAPPVFTQKPSPIGALKGSDVVFQCEISGTPPFEVVWVKDR-KQVRSSKKFKITSKNFDA 6496
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHG 1700
L I + D G Y C A N+ G
Sbjct: 6497 SLHILNLEAADVGEYYCKATNEVG 6520
Score = 286 bits (732), Expect = 5e-77
Identities = 176/566 (31%), Positives = 266/566 (46%), Gaps = 1/566 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ + SA+ Q +AG+P I ++W K D L + F NNVATL VD+ SG
Sbjct: 5040 ITTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVHISFVNNVATLQIRSVDNGHSG 5099
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C+A+N G FL VQE P + + V T PV EC V+G+ + V
Sbjct: 5100 RYTCQAKNESGVERCYAFLLVQE---PAQIIEKAKSVDVTERDPVTLECVVAGTPELKVK 5156
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W KDG+ + SF +NVA+ I + +G+Y+ N GS+S A L + +
Sbjct: 5157 WLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGEYTFKVENDFGSSSCDAYLRVLDQ 5216
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F L +D V+G S EC V+G+ PI W KD +EI + Y++ EN+
Sbjct: 5217 NIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHENTVS 5276
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + ++ DT YTC N G +C+ L +KE PPSF K E + ++
Sbjct: 5277 LDVNNLELEDTANYTCRVSNVAGDAACSGILTVKE---PPSFLVK-PERQQAIPDSTVEF 5332
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+ + G+ P + W+K++VE+ C I + + L + G YTC+V+ND G
Sbjct: 5333 KAVLKGTPPFKIKWFKDDVELASGPKCFIGLEGSTSFLNLYSVDASKTGQYTCQVTNDVG 5392
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPV-TVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
S CT+++++ E PP F + L V G+ +L C + GS IR+ W + E+
Sbjct: 5393 SDSCTTTLLVTE---PPKFVKKLEATKIVKAGDSARLECKITGSPDIRVVWYRNEHELPA 5449
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
SD+ +F + AVL+ + D GD++C+A N AGS + +KV
Sbjct: 5450 SDKYRMAFIDSVAVLQMNYLGTEDTGDFICEAQNPAGSTSCSTKV--------------- 5494
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
V F S P + ++ + ++ G P V W K K RQL + I K
Sbjct: 5495 IVKEPPVFSSFPPVVETLKNAEVSIECELSGTPPFEVVWYKDK-RQLRSSKKYKIASKNF 5553
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHG 1700
A + I + D G Y C A N+ G
Sbjct: 5554 HASIHILNVDTLDIGEYHCKAQNEVG 5579
Score = 280 bits (715), Expect = 4e-75
Identities = 166/606 (27%), Positives = 293/606 (48%), Gaps = 1/606 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G +A+ Q L G+ I V+W K + ++ +M F NNVA+L + ++ G+Y+C+
Sbjct: 4483 GGTAAFQATLKGSLPITVTWLKDNEEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQ 4542
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A+N G L+V+E P + + + T G P + SG++ I+ WFKDG
Sbjct: 4543 AKNDAGIQRCFAVLSVKE---PATIIEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDG 4599
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ L G + S D V+ L I T++ +G+Y+ N +G +S A + + + PP
Sbjct: 4600 QELTLGQKYKISVTDTVSILKIISTEKRDSGEYTFEVQNDVGRSSCKASINVLDLIIPPS 4659
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L +D++ G S D EC V G+ PI + W KD++EI + Y+ S+ +N+A L I +
Sbjct: 4660 FTKKLKKMDSIKGSSIDLECIVAGSHPISIQWFKDDQEITASEKYKFSFHDNTAFLEISQ 4719
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
++ D+G YTC A N+ G + C+ L +KE PP F +K ++ + +L+ V
Sbjct: 4720 LEGSDSGTYTCSATNKAGHNQCSGHLTVKE---PPYFLEK-PQSQDVNPNTRVQLKALVG 4775
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+ P+++ W+K+N E+H A + + + +L++ A D+G Y C++SND G+A
Sbjct: 4776 GTAPMTIKWFKDNKELHSGAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGTATTK 4835
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTV-SEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+S+ +KE PP F + +PV V G+ C + G+ IR+ W G EI ++
Sbjct: 4836 ASLFVKE---PPQFIKKPSPVLVLRNGQSTTFECQITGTPEIRVSWYLDGNEITAVEKHG 4892
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF +G A + ++G YVC+A N AG+ + ++ V
Sbjct: 4893 ISFIDGLATFQISGARVENSGTYVCEAQNDAGTASCSIEL---------------KVKEP 4937
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F+ E + + VV+ + +V G V W + +++ + + + L
Sbjct: 4938 PTFIRELKPVEVVKDSDVELECEVMGTSPFQVTWLRNN-KEIRSSKKYTLTDRVSVFNLN 4996
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAGE 1817
I +D+G Y+C+ N+ G + + + E K ++ +LK + +
Sbjct: 4997 INRCDPSDTGDYQCIVSNEGGSCSCSARVSLKEPPSFIKKIENITTVLKSSATFQSTVAG 5056
Query: 1818 EEEIDI 1835
I I
Sbjct: 5057 SPPISI 5062
Score = 279 bits (714), Expect = 6e-75
Identities = 169/565 (29%), Positives = 274/565 (48%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++VT GD A+L+ +AGTPE+ WYK L + Y++ F+NNVA L F + +DSG
Sbjct: 4009 IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSG 4068
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y N VG S T TV ++ + P F++ LR+V V +C ++GS P+ VS
Sbjct: 4069 QYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVSGTCRLDCKIAGSLPMRVS 4128
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKDG+ + + +F++ A+L I + D S AG ++C ATN +GS S LI+ E
Sbjct: 4129 WFKDGKEVTSSDRYRIAFVEGTASLEISRVDMSDAGNFTCRATNSVGSKDCSGALIVQE- 4187
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F A D + G + + G+ P + W K ++E+ SGGN I+ +
Sbjct: 4188 --PPSFVTKPASKDILPGSAVFLKSTFQGSTPFTIRWFKGDKELVSGGNCYINKEALESS 4245
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + V D+G YTC N G C+A L +KE P +F ++L + +G++ +L
Sbjct: 4246 LELYSVKTTDSGTYTCKVSNVAGAVECSANLFVKE---PATFVERLELSQXLKKGDTTQL 4302
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+V G+ PI + W+ N+ EI ++ +++F + +L++ ++ D+G Y C+ N+AG
Sbjct: 4303 ACKVTGTPPIKITWFANDREIKESSKHKMSFVESTAVLRLTDIAVEDSGEYMCEAQNEAG 4362
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
S C+S +++KE P F + P+ V + + L V G+ P I W K ++
Sbjct: 4363 SDHCSSILIVKE---SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSG 4419
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + L+ AD G Y C+ +N GS T ++VT
Sbjct: 4420 RKYKTFIQDRLVSLQILKFVAADVGKYQCRVTNEVGSSTCSARVTLREPPT--------- 4470
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FV + +S + TA F A + G V W K ++ + I + + +
Sbjct: 4471 ------FVKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDN-EEITEDDNIRMTFENNV 4523
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHG 1700
A L + G Y C A N G
Sbjct: 4524 ASLYLSGIEVKHDGKYVCQAKNDAG 4548
Score = 275 bits (704), Expect = 8e-74
Identities = 173/581 (29%), Positives = 284/581 (48%), Gaps = 3/581 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++V L ++AGTP ++W+K +T LR YK ++ + +L + + D
Sbjct: 4384 PIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFIQDRLVSLQILKFVAADV 4443
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y CR N VG + S +T++E PP+F +++ G F+ + GS PI+V
Sbjct: 4444 GKYQCRVTNEVGSSTCSARVTLRE---PPTFVKKIESTSSLRGGTAAFQATLKGSLPITV 4500
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD + + NI+ +F +NVA+L + + G+Y C A N G A L + E
Sbjct: 4501 TWLKDNEEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCFAVLSVKE 4560
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P +D G+ A + +GT+ I W KD +E+ G Y+IS + +
Sbjct: 4561 ---PATIIEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGQKYKISVTDTVS 4617
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I+ +K D+G+YT N+VG+ SC A +N+ + +IPPSFTKKL + ++ +G+S
Sbjct: 4618 ILKIISTEKRDSGEYTFEVQNDVGRSSCKASINVLDLIIPPSFTKKLKK-MDSIKGSSID 4676
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE VAGS PIS+ W+K++ EI + + +F +N L++ + D+G YTC +N A
Sbjct: 4677 LECIVAGSHPISIQWFKDDQEITASEKYKFSFHDNTAFLEISQLEGSDSGTYTCSATNKA 4736
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G C+ + +KE PP F + V+ +QL V G+ P+ I+W K +E+
Sbjct: 4737 GHNQCSGHLTVKE---PPYFLEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHS 4793
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + +LE AD+G Y+C+ SN G+ T+K+ +
Sbjct: 4794 GAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGTATTKASL--------------- 4838
Query: 1443 XVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDPIPNVKW--TKGKWRQLNQGGRIFIHQ 1613
V F+ +P + V+ + TF ++ G P V W + + + G FI
Sbjct: 4839 FVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPEIRVSWYLDGNEITAVEKHGISFI-- 4896
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A +I +SG Y C A N G ++ L+V E
Sbjct: 4897 -DGLATFQISGARVENSGTYVCEAQNDAGTASCSIELKVKE 4936
Score = 273 bits (698), Expect = 4e-73
Identities = 171/579 (29%), Positives = 279/579 (48%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+V L+C++ GT V+W + + ++R + Y + R +V L N+ D +D+
Sbjct: 4946 PVEVVKDSDVELECEVMGTSPFQVTWLRNNKEIRSSKKYTLTDRVSVFNLNINRCDPSDT 5005
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y C N G S S ++++E PPSF +++ ++ + F+ V+GS PIS+
Sbjct: 5006 GDYQCIVSNEGGSCSCSARVSLKE---PPSFIKKIENITTVLKSSATFQSTVAGSPPISI 5062
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD + L + N+ SF++NVATL I D +G+Y+C A N G A L++ E
Sbjct: 5063 TWLKDDQILDEDDNVHISFVNNVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQE 5122
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P VD + EC V GT +KV W KD ++I + +S+ N A
Sbjct: 5123 ---PAQIIEKAKSVDVTERDPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVA 5179
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
I V K D+G+YT N+ G SC A L + ++ IPPSFTKKL++ +++ G+S
Sbjct: 5180 SFRIQSVMKQDSGEYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTK-MDKVLGSSIH 5238
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
+E +V+GS PIS W+K+ EI +A + N + L V + D YTC+VSN A
Sbjct: 5239 MECKVSGSLPISAQWFKDGKEISTSAKYRLVCHENTVSLDVNNLELEDTANYTCRVSNVA 5298
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G A C+ + +KEP V + + S EF + ++G+ P +I+W K E+
Sbjct: 5299 GDAACSGILTVKEPPSFLVKPERQQAIPDSTVEFKAV---LKGTPPFKIKWFKDDVELAS 5355
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+C T+ L V + G Y C+ +N GSD+ + +
Sbjct: 5356 GPKCFIGLEGSTSFLNLYSVDASKTGQYTCQVTNDVGSDSCTTTL--------------- 5400
Query: 1443 XVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V FV + ++ ++V+ +A K+ G P V W + + +L + +
Sbjct: 5401 LVTEPPKFVKKLEATKIVKAGDSARLECKITGSPDIRVVWYRNE-HELPASDKYRMAFID 5459
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L++ D+G + C A N G + + V E
Sbjct: 5460 SVAVLQMNYLGTEDTGDFICEAQNPAGSTSCSTKVIVKE 5498
Score = 273 bits (698), Expect = 4e-73
Identities = 178/577 (30%), Positives = 271/577 (46%), Gaps = 2/577 (0%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWY--KGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VGD+ L+ + G I V W KGD +R + ++ F +NVATL +++DSG+Y
Sbjct: 6547 VGDAVELRAVVEGFQPISVVWLKDKGDV-IRESENTRISFVDNVATLQLGSPEASDSGKY 6605
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
+C+ +N G S LTV E P + + T G EC V+G+ +S WF
Sbjct: 6606 VCQIKNDAGMRECSAILTVLE---PARIIEKPEPMTVTTGNAFALECVVTGTPELSAKWF 6662
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDGR + +F++ VA+L I + S G YS N +G ++ + + +++
Sbjct: 6663 KDGREIAADSKHHITFVNKVASLKIPCAEMSDKGLYSFEVKNSVGKSTCTVSVHVSDRIV 6722
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
P F L ++A+VG S EC V+G+ PI V W +D EI SG Q S+ EN L
Sbjct: 6723 APSFIRKLKDINAIVGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLN 6782
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
+ ++ DTG YTC A N G D C+A L I+E PPSF ++ ++VE G S
Sbjct: 6783 LSFLEPSDTGTYTCVAANVAGSDECSAVLTIQE---PPSF-EQTPDSVEVLPGTSLTFTS 6838
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
+ G+ P V W+K + E+ +C I+ ++ L++ + +G Y+C V+NDAGSA
Sbjct: 6839 VIRGTPPFKVKWFKGSRELVSGESCSISLEDFVTELELFEVEPLQSGDYSCLVTNDAGSA 6898
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
CT+ + +KE P F + L +V G + L G+ PI + W+K + S
Sbjct: 6899 SCTAHLFVKE---PATFVKRLADFSVETGSPIVLEATFTGTPPISVSWMKNEFALTQSQN 6955
Query: 1272 CSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVD 1451
CS + + +LE D T D Y C N AG D + V+
Sbjct: 6956 CSITMTEKSTILEILDSTIEDYAQYSCLIENEAGQDICDAVVSVLEPP------------ 7003
Query: 1452 GKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAK 1631
+F+ + + V T KV G P + W K + +L + K + A
Sbjct: 7004 ---YFIEPLEHVEAVIGEPITLQCKVDGTPEIRISWYK-EHTKLRSAPAYKMQFKNNVAS 7059
Query: 1632 LEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
L I +D G Y C A N G + S+ L + ERK
Sbjct: 7060 LVINKVDHSDVGEYTCKAENIVGAVASSSVLVIKERK 7096
Score = 267 bits (683), Expect = 2e-71
Identities = 173/579 (29%), Positives = 269/579 (46%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+ + L+ Q+ ++ ++W K KL P YK++F + +A+L DS
Sbjct: 3635 PVQSAINKKIHLEGQVDEDRKVTITWSKNGQKLPPGKDYKIYFEDKIASLEIPLAKLKDS 3694
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-GLPVVFECAVSGSEPIS 359
G Y+C A N G S+S +T++E PPSF +++ + G C + GS I
Sbjct: 3695 GTYVCTASNEAGSSSTSATVTIRE---PPSFVKKVDPSYLMLPGESARLHCRLKGSPVIQ 3751
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V+WFK+ + L + I+ SF+++ A L+I +G YSC A N +GS S SA +++
Sbjct: 3752 VTWFKNNKELTESNTIRMSFVNSEAVLDITDVKVEDSGTYSCEAVNDVGSDSCSAEIVVK 3811
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E PP F L P D V G +A +C + GT P +++W KD ++IRS Y++ +++
Sbjct: 3812 E---PPSFIKTLEPADIVRGTNALLQCEIAGTGPFEISWFKDKKQIRSSKKYRLFSQKST 3868
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I + D G Y C NEVGK C A +KE PP+F KK+ + G +
Sbjct: 3869 VSLEIFSFNSADVGDYECVVANEVGKCGCVATHLLKE---PPTFVKKVDD-FTALAGQTV 3924
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L+ V GS+PISV W K I +++F N +L + + YTC N+
Sbjct: 3925 TLQAAVRGSEPISVTWMKGQEIIKEDGKIKMSFANGVAVLIIPDVQISFGDKYTCLAENE 3984
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS +++KEP K + + V+ G+ L V G+ ++ +W K GR +
Sbjct: 3985 AGSQTSVGELIVKEPAK---IIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLV 4041
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
S + SF N A L+F D+G Y + SN GS + ++P P V W K G + + Q+ +LEI++ +D GLY C N GE
Sbjct: 1777 LPEPTVTWYK-------DGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGE 1829
Query: 1704 IESNVNLQV 1730
L V
Sbjct: 1830 AVRTFTLTV 1838
Score = 146 bits (369), Expect = 6e-35
Identities = 139/589 (23%), Positives = 230/589 (39%), Gaps = 14/589 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK G +L+C G P +SW+ + + ++ +V L SG
Sbjct: 324 VKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRL--ESPGEASSG 381
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C A + GE + VQ +PP + L V VG P+ C SGS +
Sbjct: 382 LYSCVASSPAGEAVLQYSVEVQ---VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT 438
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
+ W ++GRP ++ +Q + TL+I + +G ++C ATN G+A + + +
Sbjct: 439 IQWLQNGRPAEELAGVQVA--SQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVH 496
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFEC----------HVTGTQPIKVAWAKDNREIRSGG 689
P ++P+ + F P+ W
Sbjct: 497 GEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPT 556
Query: 690 NYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK-KLS 866
++Y L I KVD D G YTC A N G+ L + L+PP+ ++
Sbjct: 557 GIPVAY-SLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKV---LVPPNIEPGPVN 612
Query: 867 ETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGD 1046
+ V E S LE +G P V+W+K + + ++ +T + +L++++A + D
Sbjct: 613 KAV--LENASVTLECLASGVPPPDVSWFKGHQPV--SSWMGVTVSVDGRVLRIEQAQLSD 668
Query: 1047 AGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIR 1226
AG Y C SN AGS + + P + + PV V+ ++L+C+ G+
Sbjct: 669 AGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTP--VRLTCNATGAPSPT 726
Query: 1227 IQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXX 1406
+ WLK G + P+ G VL +D+G Y C A + G D
Sbjct: 727 LMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQ------- 779
Query: 1407 XXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQL 1583
V + E ++ VV + + P P + W K G+ +
Sbjct: 780 --------DVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEP 831
Query: 1584 NQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
G +H D+A L++ D+G Y C A N+ G E + NL V
Sbjct: 832 RPG----VHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNV 876
Score = 142 bits (359), Expect = 9e-34
Identities = 147/574 (25%), Positives = 220/574 (38%), Gaps = 1/574 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTAT-YKMHFRNNVATLVFNQVDSNDSGE 188
VT+ L C G P VSW K +L + Y++ + L Q +G
Sbjct: 2586 VTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRV---SPSGALEIGQALPIHAGR 2642
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y C A NS G FLTVQ + +R V E V+ C SG +++W
Sbjct: 2643 YTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEE---EVLLPCEASGIPRPTITW 2699
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K+G + G + T L L I AG Y C A N GSA RL++ +
Sbjct: 2700 QKEGLNVATG--VSTQVLPG-GQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVV---Q 2753
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP + L + G A C G+ + W KD + + SG + + ++ S L
Sbjct: 2754 VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPV-SGAEGKFT-IQPSGEL 2811
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
+ ++ D G YTC A N VG+ L I L+ P FT + G+ L
Sbjct: 2812 LVKNLEGQDAGTYTCTAENAVGRARRRVHLTI---LVLPVFTTLPGDRSLRL-GDRLWLR 2867
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
GS + W N+ + ++ ++ LQ S D+G Y C N G
Sbjct: 2868 CAARGSPTPRIGWTVNDRPVTEG----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGR 2923
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
S + +KE P + + + + G +QL C VRG I W+K G ++ S
Sbjct: 2924 TQAVSFVHVKEA--PVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGS- 2980
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
NG+ L + + DAG Y C A N G +K V +
Sbjct: 2981 HLRHQLQNGS--LTIRRTERDDAGRYQCLAENEMG--VAKKVVILV-------------L 3023
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F EPQ + V + G+P P ++W + + L R+ + +
Sbjct: 3024 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQA-GQPLRASRRL---RTLPDG 3079
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
L + + D+G Y CVA N G + L V
Sbjct: 3080 SLWLENVETGDAGTYDCVAHNLLGSATARAFLVV 3113
Score = 141 bits (356), Expect = 2e-33
Identities = 145/580 (25%), Positives = 227/580 (39%), Gaps = 3/580 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V+V +A L CQ G P VSW K L P + +L V + D+G
Sbjct: 2400 VNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPE--GSLRIQPVLAQDAG 2457
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y+C A NS G L V E PP+ + ++ T P + C SGS V
Sbjct: 2458 HYLCLASNSAGSDRQGRDLRVLE---PPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVV 2514
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+KDG+ L L L + + Q+ C +N +G A RL
Sbjct: 2515 WWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAH---RLYQVTV 2571
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRS-GGNYQISYLENSA 722
PP + CH TG V+W+K ++ + G Y++S S
Sbjct: 2572 HVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVS---PSG 2628
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I + G+YTC A N G A ++ + K L V
Sbjct: 2629 ALEIGQALPIHAGRYTCSARNSAG----VAHKHVFLTVQASPVVKPLPSVVRAVAEEEVL 2684
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L +G ++ W K + + + ++ L++ AS DAG Y C N A
Sbjct: 2685 LPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQ---LRIAHASPEDAGNYLCIAKNSA 2741
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GSA+ + +V+ + PPV + L ++ +EG L C RGS I W K G+ +
Sbjct: 2742 GSAMGKTRLVV---QVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG 2798
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
++ F+ +L K++ DAG Y C A N G + +T
Sbjct: 2799 AEG-KFTIQPSGELL-VKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLP--------- 2847
Query: 1443 XVDGKLFFVSEP--QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
F + P +S+R+ ++ A+ G P P + WT R + +G + ++
Sbjct: 2848 ------VFTTLPGDRSLRLGDRLWLRCAAR--GSPTPRIGWTVND-RPVTEG----VSEQ 2894
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ L+ ++ DSG Y C A N+ G ++ + V E
Sbjct: 2895 DGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKE 2934
Score = 137 bits (346), Expect = 3e-32
Identities = 138/601 (22%), Positives = 228/601 (37%), Gaps = 35/601 (5%)
Frame = +3
Query: 36 LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSV 215
L C+ G P ++W+K D L PT+T ++ R L + S+D+G Y C+A N+V
Sbjct: 240 LLCEARGVPTPNITWFK-DGALLPTSTKVVYTRGG-RQLQLGRAQSSDAGVYTCKASNAV 297
Query: 216 GEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKD 395
G +T L V + V+ G PV EC G ++SW +G P+ +
Sbjct: 298 GAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAE 357
Query: 396 GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSA--------SSSARLILTEGRN 551
+ ++ + + L + + +G YSC A++P G A +L++ EG
Sbjct: 358 --SNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEG-- 413
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
L V +VG+ + C +G+ + W ++ R Q++ + H+
Sbjct: 414 -------LGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHID 466
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
+++D +G + C A NE G ++++ P + + E +S
Sbjct: 467 HVELD--HSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHS---SF 521
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALL----------------LQVKKASMG 1043
A P+ W HP + + L LQ++K +
Sbjct: 522 PAACDPPVHRGW-----GAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLR 576
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
D G+YTC +N AG + V + PP + V E + L C G P
Sbjct: 577 DEGIYTCAATNLAGE---SKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPP 633
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTX 1403
+ W K + + S + + VL + +DAG Y C ASNVAGS + +
Sbjct: 634 DVSWFKGHQPV--SSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRV 691
Query: 1404 XXXXXXXXXXXXXXVDGKLFFVSEPQSI--RVVEKTTATFIAKVGGDPIPNVKWTKG--- 1568
++ P S+ V+ T G P P + W K
Sbjct: 692 NVPPR----------------ITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNP 735
Query: 1569 ------KWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
Q+ GGR+ L + +DSG Y CVA + GE +V LQV
Sbjct: 736 VSPAGTPGLQVFPGGRV----------LTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 785
Query: 1731 N 1733
+
Sbjct: 786 H 786
Score = 127 bits (318), Expect = 5e-29
Identities = 147/583 (25%), Positives = 219/583 (37%), Gaps = 7/583 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V G L C ++G P V+W K + +A + + R L +++ +G
Sbjct: 1852 VSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGG--RLQLSRLQPAQAG 1909
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C AEN+ E + V S S R+ G V +C G P V+
Sbjct: 1910 TYTCVAENTQAEARKDFVVAVLVAPRIRS-SGVAREHHVLEGQEVRLDCEADGQPPPDVA 1968
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W KDG PL F + +L + S AG Y+C A NP G ARL
Sbjct: 1969 WLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGE---DARLHTVNV 2025
Query: 546 RNPPFFDIPLAPVDAVV---GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
PP +V GE C V G+ PI V+W KD + Q + L
Sbjct: 2026 LVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLS---QRTLLHG 2082
Query: 717 SAH-LTILKVDKGDTGQYTCYAVNEVG--KDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
S H L I KV D G +TC A + G + T Q+ + L P F V
Sbjct: 2083 SGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEF----QNDVVVVR 2138
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
G+ L G V+W K+ P + + LQ++ GD+G Y+C
Sbjct: 2139 GSLVELPCEARGVPLPLVSWMKDG---EPLLSQSL---EQGPSLQLEAVGAGDSGTYSCV 2192
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQ-HLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKA 1244
++AG A + + EP P + D T ++++ G ++L C +G+ I W K
Sbjct: 2193 AVSEAGEARRHFQLTVMEP--PHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKD 2250
Query: 1245 GREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXX 1424
G+ + + S T VL +D AG Y C A + AG+ +V
Sbjct: 2251 GQALTRLENNS----RATRVLRVRD-----AGLYTCLAESPAGAIEKSFRVRVQAPPNIV 2301
Query: 1425 XXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIF 1604
G F V V+E V +P P + W + L +
Sbjct: 2302 GPR------GPRFVVGLAPGQLVLE-------CSVEAEPAPKITWHRDGI-VLQEDAHTQ 2347
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
++G +L+ T DSG Y C A N G ++++
Sbjct: 2348 FPERGRFLQLQALSTA--DSGDYSCTARNAAGSTSVAFRVEIH 2388
Score = 124 bits (312), Expect = 2e-28
Identities = 140/568 (24%), Positives = 211/568 (37%), Gaps = 7/568 (1%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G+ ++ C + G+P I VSW K L + +H + TL ++V D+G + C
Sbjct: 2046 GELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGH--TLRISKVQLADAGIFTCV 2103
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A + G + L VQ + Q DV G V C G VSW KDG
Sbjct: 2104 AASPAGVADRNFTLQVQVPPVLEPVEFQ-NDVVVVRGSLVELPCEARGVPLPLVSWMKDG 2162
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
PL + L+ +L + +G YSC A + G A +L + E PP
Sbjct: 2163 EPLL------SQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVME---PPH 2213
Query: 561 FDIPLAPVDAVVGESADFE--CHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT- 731
+ P + + A E C GT + W KD + + + LEN++ T
Sbjct: 2214 IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL--------TRLENNSRATR 2265
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKLSETVEETEGNSFRLE 908
+L+V D G YTC A + G + ++ ++ PP+ + V LE
Sbjct: 2266 VLRVR--DAGLYTCLAESPAGAIEKSFRVRVQA---PPNIVGPRGPRFVVGLAPGQLVLE 2320
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
V + W+++ + + A+ + F LQ++ S D+G Y+C N AGS
Sbjct: 2321 CSVEAEPAPKITWHRDGIVLQEDAHTQ--FPERGRFLQLQALSTADSGDYSCTARNAAGS 2378
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
TS E P V VS + L C G + W K + P
Sbjct: 2379 ---TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRS 2435
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
G+ L + V DAG Y+C ASN AGSD +
Sbjct: 2436 PRFEILPEGS--LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPA---------- 2483
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWR---QLNQGGRIFIHQKG 1619
P ++ + T A + G P P V W K + +L QG +
Sbjct: 2484 -----IAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNA 2538
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
L + DS + CV N+ GE
Sbjct: 2539 ----LLLTAPGPQDSAQFECVVSNEVGE 2562
Score = 120 bits (302), Expect = 4e-27
Identities = 114/459 (24%), Positives = 191/459 (41%), Gaps = 7/459 (1%)
Frame = +3
Query: 45 QLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEV 224
QL G P +G + Y D +++ + +L F ++ DSG Y CRAEN G
Sbjct: 57 QLVGVP-LGWAGYGWDLGWGQVGGHRL--LDEGQSLHFPRIQEGDSGLYSCRAENQAGTA 113
Query: 225 SSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRP-LKD 395
L V PPS + ++V G V +C SG V W KD +P L
Sbjct: 114 QRDFHLLV---LTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPG 170
Query: 396 GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP--FFDI 569
GP++Q ++ L I + G+Y C A +P G + +L + PP +
Sbjct: 171 GPHLQVQ--EDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRV---HAPPTIWGSN 225
Query: 570 PLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDK 749
V + C G + W KD + + + ++ Y L + +
Sbjct: 226 ETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPT--STKVVYTRGGRQLQLGRAQS 283
Query: 750 GDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE--TVEETEGNSFRLEGRVAG 923
D G YTC A N VG +L++ +PP+ V+ G LE G
Sbjct: 284 SDAGVYTCKASNAVGAAEKATRLDV---YVPPTIEGAGGRPYVVKAVAGRPVALECVARG 340
Query: 924 SQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTS 1103
+++W+ + + + E + + +L+++ +GLY+C S+ AG A+
Sbjct: 341 HPSPTLSWHHEGLPV--AESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQY 398
Query: 1104 SIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFS 1283
S+ ++ P + V + L VT G+ L+L C GS IQWL+ GR + +
Sbjct: 399 SVEVQVPPQLLV-AEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAE--ELAGVQ 455
Query: 1284 FANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
A+ L V +G + C+A+N AG+ ++ +V+
Sbjct: 456 VASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVS 494
Score = 107 bits (266), Expect = 5e-23
Identities = 133/592 (22%), Positives = 215/592 (36%), Gaps = 21/592 (3%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G LQC +G P V W K + P + + + + L D G Y C
Sbjct: 141 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPH-LQVQEDGQVLRITGSHVGDEGRYQCV 199
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPISVSWFK 374
A + G+ + L V PP+ S + +V V C G +++WFK
Sbjct: 200 AFSPAGQQARDFQLRVH---APPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFK 256
Query: 375 DGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNP 554
DG L + + L + + S AG Y+C A+N +G+A + RL + P
Sbjct: 257 DGALLPTSTKV--VYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRL---DVYVP 311
Query: 555 PFFD----IPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P + P V AV G EC G ++W + + ++ + +
Sbjct: 312 PTIEGAGGRPYV-VKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLE--TDGS 368
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + + +G Y+C A + G+ Q +++ ++ P + V G
Sbjct: 369 VLRLESPGEASSGLYSCVASSPAGE--AVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLE 426
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L + +GS ++ W +N A ++ + L + + +GL+ C+ +N+A
Sbjct: 427 LPCQASGSPVPTIQWLQNGRPAEELAGVQVA--SQGTTLHIDHVELDHSGLFACQATNEA 484
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPV-TVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
G+A + + P V + P+ G S P+ W G K
Sbjct: 485 GTAGAEVEVSVHGEWAPGVLE---VPIGQYHWGXEHHSSFPAACDPPVHRGW---GAHPK 538
Query: 1260 P-------SDRCSFSFANGTAV-------LEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
P S + G V L+ + V D G Y C A+N+AG SK +V
Sbjct: 539 PPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGE--SKREV 596
Query: 1398 TXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWR 1577
P + V+E + T G P P+V W KG
Sbjct: 597 ALKVLVPPNIEPG-------------PVNKAVLENASVTLECLASGVPPPDVSWFKGHQP 643
Query: 1578 QLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
+ G + D L I +D+G YRCVA N G E L+VN
Sbjct: 644 VSSWMG---VTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVN 692
Score = 106 bits (265), Expect = 7e-23
Identities = 116/509 (22%), Positives = 191/509 (37%), Gaps = 18/509 (3%)
Frame = +3
Query: 261 LPPSFSRQLR--DVQETVGLPVVFECAVSGSEPISVSWFKD-------------GRPLKD 395
+PPS R +V G + EC +G + W KD G L
Sbjct: 15 VPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGW 74
Query: 396 GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPL 575
G LD +L+ + +G YSC A N G+A L++ P
Sbjct: 75 GQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTP--PSVLGAGA 132
Query: 576 AP-VDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKG 752
A V + G + +C +G +V W KD + + GG + + E+ L I G
Sbjct: 133 AQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPH-LQVQEDGQVLRITGSHVG 191
Query: 753 DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQP 932
D G+Y C A + G+ + QL + P + + V E + +L G
Sbjct: 192 DEGRYQCVAFSPAGQQARDFQLRVHAP--PTIWGSNETGEVAVMEDHLVQLLCEARGVPT 249
Query: 933 ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIV 1112
++ W+K+ + PT+ ++ + LQ+ +A DAG+YTCK SN G+A + +
Sbjct: 250 PNITWFKDGALL-PTST-KVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLD 307
Query: 1113 IKEPKKPPVFDQHLTPVTVS--EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSF 1286
+ P P + P V G + L C RG + W G + S+
Sbjct: 308 VYVP--PTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLE- 364
Query: 1287 ANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFF 1466
+VL + +A +G Y C AS+ AG + V V +L
Sbjct: 365 -TDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSV-------------EVQVPPQLLV 410
Query: 1467 VSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRD 1646
+ + + G P+P ++W + R + + + +G L I
Sbjct: 411 AEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQ-NGRPAEELAGVQVASQG--TTLHIDH 467
Query: 1647 TTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
SGL+ C A N+ G + V + V+
Sbjct: 468 VELDHSGLFACQATNEAGTAGAEVEVSVH 496
>ref|XP_001715206.1| PREDICTED: LOW QUALITY PROTEIN: hemicentin-2 [Homo sapiens].
Length = 3874
Score = 167 bits (423), Expect = 3e-41
Identities = 155/592 (26%), Positives = 225/592 (38%), Gaps = 7/592 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + SLQC G P +SW + P+ ++ + L + + D+
Sbjct: 1664 VTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSP--RLQVLEDGQVLQVSTAEVADAA 1721
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y+C AEN G S+ T++ Q P L V + V C V V+
Sbjct: 1722 SYMCVAENQAG--SAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVT 1779
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+KD + L G + L TL + + S +G Y+C A N G +L +
Sbjct: 1780 WYKDSQALSLGEEV--FLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVP 1837
Query: 546 RNPPFFDIPLAPVDAV---VGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
P F P P DAV VG+ A C V W KD + + Q L
Sbjct: 1838 --PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQA--LRG 1893
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
L I + D G Y+C N G+ T L ++ +PP+F +ETV + G+
Sbjct: 1894 GQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ---VPPTFENPKTETVSQVAGSP 1950
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
L V+G +V W K+ + + +A + + L Q+ + AG YTC N
Sbjct: 1951 LVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRL--QLSRLQPAQAGTYTCVAEN 2008
Query: 1077 DAGSA---LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
A + +V + V +H V EG+ ++L C G P + WLK G
Sbjct: 2009 TQAEARKDFVVAVLVAPRIRSSGVAREH----HVLEGQEVRLDCEADGQPPPDVAWLKDG 2064
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
+ F L K + +DAG Y C A N AG D V
Sbjct: 2065 SPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQ 2124
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQLNQGGRIF 1604
DG VS P + T + V G P +V W K G L+Q R
Sbjct: 2125 G-----ADGSGTLVSRPGEL-------VTMVCPVRGSPPIHVSWLKDGLPLPLSQ--RTL 2170
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIE 1760
+H G L I D+G++ CVA + G + N LQV E +E
Sbjct: 2171 LHGSGHT--LRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVE 2220
Score = 162 bits (410), Expect = 1e-39
Identities = 161/590 (27%), Positives = 229/590 (38%), Gaps = 13/590 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V + S SL C + P V+WYK L + ++ TL + +DSG
Sbjct: 1756 VTAILNSSVSLPCDVHAHPNPEVTWYKDSQAL--SLGEEVFLLPGTHTLQLGRARLSDSG 1813
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV----GLPVVFECAVSGSEP 353
Y C A N+ G L+V +PP+F + R Q+ V G V C
Sbjct: 1814 MYTCEALNAAGRDQKLVQLSVL---VPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPE 1870
Query: 354 ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
+V+W+KDG+PL Q L L I + S G YSC +N G A + L
Sbjct: 1871 PTVTWYKDGQPLVLAQRTQA--LRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLT 1928
Query: 534 LTEGRNPPFFDIPLAP-VDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
+ + PP F+ P V V G C V+G V W KD + S + + +
Sbjct: 1929 V---QVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGV--V 1983
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVN---EVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
L + ++ G YTC A N E KD A L + P + ++
Sbjct: 1984 SRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVL-----VAPRIRSSGVAREHHV 2038
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
EG RL+ G P VAW K+ + + F + L +K DAG YT
Sbjct: 2039 LEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYT 2098
Query: 1062 CKVSNDAG--SALCTSSIVIKEPKKPPVFDQHLT---PVTVSEGEFLQLSCHVRGSEPIR 1226
C N AG + L T ++++ PP Q + GE + + C VRGS PI
Sbjct: 2099 CVAHNPAGEDARLHTVNVLV-----PPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIH 2153
Query: 1227 IQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXX 1406
+ WLK G + S R + T L V ADAG + C A++ AG +
Sbjct: 2154 VSWLKDGLPLPLSQRTLLHGSGHT--LRISKVQLADAGIFTCVAASPAGVADRNFTLQVQ 2211
Query: 1407 XXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLN 1586
V L V + VV + + G P+P V W K L+
Sbjct: 2212 -------------VPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLS 2258
Query: 1587 QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
Q ++G +LE DSG Y CVA ++ GE + L V E
Sbjct: 2259 QS-----LEQGPSLQLEA--VGAGDSGTYSCVAVSEAGEARRHFQLTVME 2301
Score = 162 bits (410), Expect = 1e-39
Identities = 145/581 (24%), Positives = 233/581 (40%), Gaps = 6/581 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V VGD A L C+ PE V+WYK L + L + +D G
Sbjct: 1851 VLVRVGDKAVLSCETDALPEPTVTWYKDGQPL--VLAQRTQALRGGQRLEIQEAQVSDKG 1908
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSR-QLRDVQETVGLPVVFECAVSGSEPISV 362
Y C+ N GE + LTVQ +PP+F + V + G P+V C VSG +V
Sbjct: 1909 LYSCKVSNVAGEAVRTFTLTVQ---VPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTV 1965
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD P++ + + L + + + AG Y+C A N A + ++
Sbjct: 1966 TWLKDRMPVES--SAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENT--QAEARKDFVVAV 2021
Query: 543 GRNPPFFDIPLAPVDAVV-GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
P +A V+ G+ +C G P VAW KD + + + +
Sbjct: 2022 LVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDG 2081
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKL--SETVEETEGN 893
L + + D G YTC A N G+D A+L+ L+PP+ + S T+ G
Sbjct: 2082 GSLVLKGLRASDAGAYTCVAHNPAGED---ARLHTVNVLVPPTIKQGADGSGTLVSRPGE 2138
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
+ V GS PI V+W K+ + + + + L++ K + DAG++TC +
Sbjct: 2139 LVTMVCPVRGSPPIHVSWLKDGLPL--PLSQRTLLHGSGHTLRISKVQLADAGIFTCVAA 2196
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFD--QHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
+ AG A ++ + + PPV + + V V G ++L C RG + W+K G
Sbjct: 2197 SPAGVADRNFTLQV---QVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDG 2253
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
+ S S G + L+ + V D+G Y C A + AG ++T
Sbjct: 2254 EPL-----LSQSLEQGPS-LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIED 2307
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
+P + + + G P PN+ W K G +
Sbjct: 2308 S-------------GQPTELSLTPGAPMELLCDAQGTPQPNITWHK-------DGQALTR 2347
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ A +R D+GLY C+A + G IE + ++V
Sbjct: 2348 LENNSRATRVLR---VRDAGLYTCLAESPAGAIEKSFRVRV 2385
Score = 158 bits (400), Expect = 2e-38
Identities = 140/530 (26%), Positives = 206/530 (38%), Gaps = 3/530 (0%)
Frame = +3
Query: 150 LVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFE 329
L +VD D G Y C A N GE L V +PP+ + V E
Sbjct: 659 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVL---VPPNIEPGPVNKAVLENASVTLE 715
Query: 330 CAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGS 509
C SG P VSWFK +P+ + S V L I Q S AG Y C A+N GS
Sbjct: 716 CLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRV--LRIEQAQLSDAGSYRCVASNVAGS 773
Query: 510 ASSSARLILTEGRNPPFFDIPLA-PVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSG 686
L + PP +P + P +V C+ TG + W KD +
Sbjct: 774 TELRYGLRVNV---PPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPA 830
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKL 863
G + LT+ D+G+Y+C AV+ VG+D L + +PPS ++L
Sbjct: 831 GTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVH---MPPSILGEEL 887
Query: 864 SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMG 1043
+ +V E S LE + P ++W+K+ + P ++ + LLQV +A +
Sbjct: 888 NVSVVANE--SVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLS--ADKALLQVDRADVW 943
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
DAG YTC+ N AG + ++ + P+ + H +TV EG LSC RG
Sbjct: 944 DAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESH--TLTVREGHPTSLSCECRGVPFP 1001
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTA-VLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
+I W K G+ + P + + +L A G Y C+ SNV G+ + ++
Sbjct: 1002 KISWRKDGQPL-PGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLE 1060
Query: 1401 XXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQ 1580
P + VV+ AT G P P V W +
Sbjct: 1061 VHVPPQIAGPR------------EPPTQVSVVQDGVATLECNATGKPPPTVTWERD---G 1105
Query: 1581 LNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
G + + + L + +G Y CVA N G E L V
Sbjct: 1106 QPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSV 1155
Score = 156 bits (394), Expect = 8e-38
Identities = 130/500 (26%), Positives = 207/500 (41%), Gaps = 11/500 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQV------ 167
V+ + L C+ +G P ++W K NVAT V QV
Sbjct: 2766 VRAVAEEEVLLPCEASGIPRPTITWQKEGL--------------NVATGVSTQVLPGGQL 2811
Query: 168 -----DSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFEC 332
D+G Y+C A+NS G T L VQ +PP L D+ T G C
Sbjct: 2812 RIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ---VPPVIENGLPDLSTTEGSHAFLPC 2868
Query: 333 AVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSA 512
GS +++W KDG+P+ T + L + + AG Y+CTA N +G A
Sbjct: 2869 KARGSPEPNITWDKDGQPVSGAEGKFT--IQPSGELLVKNLEGQDAGTYTCTAENAVGRA 2926
Query: 513 SSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
R+ LT P F +P +G+ C G+ ++ W ++R + G
Sbjct: 2927 RR--RVHLTILVLPVFTTLP-GDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG-- 2981
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET 872
+S + + L V + D+G Y C+A N VG+ + +++KE P +
Sbjct: 2982 --VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEA---PVLQGEAFSY 3036
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAG 1052
+ E G S +L+ V G + W K+ + P + + L + + DAG
Sbjct: 3037 LVEPVGGSIQLDCVVRGDPVPDIHWIKDGL---PLRGSHLRHQLQNGSLTIHRTERDDAG 3093
Query: 1053 LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQ 1232
Y C N+ G A +VI + PVF +TV G+ + L C G I+
Sbjct: 3094 RYQCLAENEMGVA---KKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIE 3150
Query: 1233 WLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXX 1412
WL+AG+ ++ S R + +G+ LE +V DAG Y C A N+ GS T+++ +
Sbjct: 3151 WLQAGQPLRASRRLR-TLPDGSLWLE--NVETGDAGTYDCVAHNLLGSATARAFLVVRGE 3207
Query: 1413 XXXXXXXXXXXVDGKLFFVS 1472
++G+ F V+
Sbjct: 3208 PQGSWGSMTGVINGRKFGVA 3227
Score = 155 bits (393), Expect = 1e-37
Identities = 155/612 (25%), Positives = 241/612 (39%), Gaps = 46/612 (7%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTA-TYKMHFRNNVATLVFNQVDSNDSGEYICRAEN 209
+L C+ G P + W++G+ + P TY + L Q DSG Y C A N
Sbjct: 1180 TLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLA---GGWMLKMTQTQEQDSGLYSCLASN 1236
Query: 210 SVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV----GLPVVFECAVSGSEPISVSWFKD 377
GE + + V +PPS + D++E + G C V+G ++WFKD
Sbjct: 1237 EAGEARRNFSVEVL---VPPSIENE--DLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKD 1291
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
GRPL G S + L + Q + S AG YSC A N +G + +L
Sbjct: 1292 GRPLARGDAHHIS--PDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQL--------- 1340
Query: 558 FFDIPLAPVDAVVG---ESADFECHVTGTQPIK------------VAWAKDNREIRSGGN 692
+ LAP ++G +SAD E VT PI + W KD + N
Sbjct: 1341 --SVLLAPT--ILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRN 1396
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK--KLS 866
Q+ L + L IL K D GQYTC NE+G+ + + LIPPS +K L
Sbjct: 1397 IQL--LPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEV---LIPPSISKDDPLG 1451
Query: 867 ET----VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKA 1034
E V+ ++ LE P ++ WYK+ + P++ ++ LLQ++
Sbjct: 1452 EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVL--GEGRLLQIQPT 1509
Query: 1035 SMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVF----------------DQHLTPVT 1166
+ D+G Y C +N AG +++I + PP+F ++ VT
Sbjct: 1510 QVSDSGRYLCVATNVAGEDDQDFNVLI---QVPPMFQKVGDFSAAFEILSREEEARGGVT 1566
Query: 1167 ----VSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKAD 1334
+ E L C P + W + + + D S G VL+ V +
Sbjct: 1567 EYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGD--EVSVLQGGRVLQIPLVRAEN 1624
Query: 1335 AGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTAT 1514
AG Y CKASN G D ++ + + V +T +
Sbjct: 1625 AGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELV-----------EEVTVNASSTVS 1673
Query: 1515 FIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNK 1694
G+P+P + W + + R+ + + G L++ D+ Y CVA N+
Sbjct: 1674 LQCPALGNPVPTISWLQ-NGLPFSPSPRLQVLEDGQ--VLQVSTAEVADAASYMCVAENQ 1730
Query: 1695 HGEIESNVNLQV 1730
G E L+V
Sbjct: 1731 AGSAEKLFTLRV 1742
Score = 155 bits (391), Expect = 2e-37
Identities = 147/580 (25%), Positives = 220/580 (37%), Gaps = 4/580 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P V V L C G P + W K + P T + L ++DS
Sbjct: 795 PGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDS 854
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y C A ++VGE L V +PPS + +V V EC P +
Sbjct: 855 GRYSCVAVSAVGEDRQDVVLQVH---MPPSILGEELNVSVVANESVALECQSHAMPPPVL 911
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SW+KDGRPL+ P + S + A L + + D AG Y+C A N G + L +
Sbjct: 912 SWWKDGRPLEPRPGVHLS--ADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWV 969
Query: 543 GRNPPFFDIPLAPVDAV-VGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
P F + + V G C G K++W KD + + G + ++
Sbjct: 970 A---PVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPL-PGEGAGLQHVSAV 1025
Query: 720 AHLTIL-KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT--KKLSETVEETEG 890
L L + G YTC N VG S QL + +PP ++ V +
Sbjct: 1026 GRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVH---VPPQIAGPREPPTQVSVVQD 1082
Query: 891 NSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
LE G P +V W ++ + A + +N L V++A G Y+C
Sbjct: 1083 GVATLECNATGKPPPTVTWERDGQPV--GAELGLQLQNQGQSLHVERAQAAHTGRYSCVA 1140
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
N AG A + + P + LT +T + L L C G P I+W +
Sbjct: 1141 ENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEE 1200
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
+ P + ++ A G +L+ + D+G Y C ASN AG V
Sbjct: 1201 PVSPGED-TYLLAGGW-MLKMTQTQEQDSGLYSCLASNEAGEARRNFSV----------- 1247
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
V + + I+V++ TA + V G P P + W K R L +G H
Sbjct: 1248 --EVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFK-DGRPLARGDA--HH 1302
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
D L++ + +G Y C+A N GE + L V
Sbjct: 1303 ISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV 1342
Score = 154 bits (390), Expect = 2e-37
Identities = 142/582 (24%), Positives = 228/582 (39%), Gaps = 6/582 (1%)
Frame = +3
Query: 3 PVKVTVGDSAS--LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSN 176
PV V ++AS L+C +G P VSW+KG + + V L Q +
Sbjct: 701 PVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRV--LRIEQAQLS 758
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQ---EQKLPPSFSRQLRDVQETVGLPVVFECAVSGS 347
D+G Y C A N G L V LPPS + V PV C +G+
Sbjct: 759 DAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPV-----LVNTPVRLTCNATGA 813
Query: 348 EPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSAR 527
++ W KDG P+ L + S +G+YSC A + +G
Sbjct: 814 PSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQD-- 871
Query: 528 LILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISY 707
++ + PP V V ES EC P ++W KD R + +S
Sbjct: 872 -VVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLS- 929
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
+ A L + + D D G YTC A+N+ G+ LN+ + P F + S T+ E
Sbjct: 930 -ADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNV---WVAPVFPLRESHTLTVRE 985
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
G+ L G ++W K+ + LL + +A + G YTC+
Sbjct: 986 GHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCE 1045
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
SN G++ + + P + + T V+V + L C+ G P + W + G
Sbjct: 1046 CSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDG 1105
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
+ + N L + A G Y C A N+AG K +++
Sbjct: 1106 QPV--GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELS--------- 1154
Query: 1428 XXXXXXVDGKLFFVSEP-QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIF 1604
V +L +P +I + T + + G P P ++W +G+ ++ G +
Sbjct: 1155 ----VLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGE-EPVSPGEDTY 1209
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ G L++ T + DSGLY C+A N+ GE N +++V
Sbjct: 1210 LLAGG--WMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEV 1249
Score = 152 bits (384), Expect = 1e-36
Identities = 156/625 (24%), Positives = 242/625 (38%), Gaps = 19/625 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G SL C+ G P +SW K L H L Q G Y
Sbjct: 983 VREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTY 1042
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFS------RQLRDVQETVGLPVVFECAVSGSEP 353
C N VG S L V +PP + Q+ VQ+ V EC +G P
Sbjct: 1043 TCECSNVVGNSSQDLQLEVH---VPPQIAGPREPPTQVSVVQDGVA---TLECNATGKPP 1096
Query: 354 ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
+V+W +DG+P+ G + + +L++ + + G+YSC A N G A L
Sbjct: 1097 PTVTWERDGQPV--GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELS 1154
Query: 534 LTEGRNPPFF--DI-PLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
+ PP D+ PL + A + C G P + W + + G + +
Sbjct: 1155 VLV---PPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYL- 1210
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIK-ERLIPPSFTKK-LSETVE 878
L L + + + D+G Y+C A NE G+ A+ N E L+PPS + L E ++
Sbjct: 1211 -LAGGWMLKMTQTQEQDSGLYSCLASNEAGE----ARRNFSVEVLVPPSIENEDLEEVIK 1265
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEIT-FKNNALLLQVKKASMGDAGL 1055
+G + L V G + W+K+ P A + + +LLQV +A++ AG
Sbjct: 1266 VLDGQTAHLMCNVTGHPQPKLTWFKDG---RPLARGDAHHISPDGVLLQVLQANLSSAGH 1322
Query: 1056 YTCKVSNDAGSALCTSSIVIKEPKKPPVF----DQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
Y+C +N G T + P + D VTV+ + L C
Sbjct: 1323 YSCIAANAVGEK--TKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSP 1380
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTX 1403
I W+K G + S + GT L+ + K DAG Y C +N G V
Sbjct: 1381 NITWMKDGAPFEASR--NIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEV 1438
Query: 1404 XXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQL 1583
V K ++ +T T + P P ++W K + +
Sbjct: 1439 LIPPSISKDDPLGEVGVK--------EVKTKVNSTLTLECESWAVPPPTIRWYKDG-QPV 1489
Query: 1584 NQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEG 1763
R+ + G+ L+I+ T +DSG Y CVA N GE + + N+ + +K+ G
Sbjct: 1490 TPSSRLQV--LGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKV-G 1546
Query: 1764 DLRA---MLKKTPVLKKGAGEEEEI 1829
D A +L + + G E EI
Sbjct: 1547 DFSAAFEILSREEEARGGVTEYREI 1571
Score = 151 bits (382), Expect = 2e-36
Identities = 145/573 (25%), Positives = 236/573 (41%), Gaps = 8/573 (1%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
++ + A L C P ++WY+ D L +A ++ L V + ++G
Sbjct: 1570 EIVENNPAYLYCDTNAIPPPDLTWYREDQPL--SAGDEVSVLQGGRVLQIPLVRAENAGR 1627
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQL-RDVQETVGLPVVFECAVSGSEPISVS 365
Y C+A N VGE L V + + +L +V V +C G+ ++S
Sbjct: 1628 YSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTIS 1687
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W ++G P P +Q L++ L + + + A Y C A N GSA +L
Sbjct: 1688 WLQNGLPFSPSPRLQV--LEDGQVLQVSTAEVADAASYMCVAENQAGSAE---KLFTLRV 1742
Query: 546 RNPP-FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ PP + L V A++ S C V +V W KD++ + G ++ L +
Sbjct: 1743 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGE--EVFLLPGTH 1800
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF---TKKLSETVEETEGN 893
L + + D+G YTC A+N G+D QL++ L+PP+F + + V G+
Sbjct: 1801 TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSV---LVPPAFRQAPRGPQDAVLVRVGD 1857
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
L +V WYK+ + + L++++A + D GLY+CKVS
Sbjct: 1858 KAVLSCETDALPEPTVTWYKDGQPLVLAQRTQAL--RGGQRLEIQEAQVSDKGLYSCKVS 1915
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSE--GEFLQLSCHVRGSEPIRIQWLKAG 1247
N AG A+ T ++ + + PP F+ T TVS+ G L L+C V G + WLK
Sbjct: 1916 NVAGEAVRTFTLTV---QVPPTFENPKTE-TVSQVAGSPLVLTCDVSGVPAPTVTWLKDR 1971
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
++ S G L+ + A AG Y C A N ++ K V
Sbjct: 1972 MPVESSAVHGVVSRGGR--LQLSRLQPAQAGTYTCVAENTQ-AEARKDFVV--------- 2019
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQLNQGGRIF 1604
V ++ + V+E + G P P+V W K G + G +
Sbjct: 2020 ---AVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLR 2076
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
+ G L ++ +D+G Y CVA N GE
Sbjct: 2077 FYLDG--GSLVLKGLRASDAGAYTCVAHNPAGE 2107
Score = 147 bits (370), Expect = 5e-35
Identities = 145/609 (23%), Positives = 235/609 (38%), Gaps = 34/609 (5%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VTV + SL C+ P ++W K A+ + L D+G
Sbjct: 1360 VTVTVNNPISLICEALAFPSPNITWMKDGAPFE--ASRNIQLLPGTHGLQILNAQKEDAG 1417
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQ-------LRDVQETVGLPVVFECAVSG 344
+Y C N +GE + + V +PPS S+ +++V+ V + EC
Sbjct: 1418 QYTCVVTNELGEAVKNYHVEVL---IPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWA 1474
Query: 345 SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
P ++ W+KDG+P+ +Q L L I T S +G+Y C ATN G
Sbjct: 1475 VPPPTIRWYKDGQPVTPSSRLQV--LGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDF 1532
Query: 525 RLILTEGRNPPFF----------DIPLAPVDA----------VVGESADFECHVTGTQPI 644
+++ + PP F +I +A V A C P
Sbjct: 1533 NVLI---QVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPP 1589
Query: 645 KVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI 824
+ W ++++ + +G ++S L+ L I V + G+Y+C A NEVG+D +L +
Sbjct: 1590 DLTWYREDQPLSAGD--EVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLV 1647
Query: 825 KERLIPPSFTKKLSETVEETEGNS---FRLEGRVAGSQPISVAWYKNNVEIHPTANCEIT 995
L PP E VEE N+ L+ G+ +++W +N + P+ ++
Sbjct: 1648 ---LTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVL 1704
Query: 996 FKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSE 1175
+ +LQV A + DA Y C N AGSA ++ ++ P P + L VT
Sbjct: 1705 --EDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVP--PRIAGLDLEQVTAIL 1760
Query: 1176 GEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCK 1355
+ L C V + W K + + + GT L+ +D+G Y C+
Sbjct: 1761 NSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFL--LPGTHTLQLGRARLSDSGMYTCE 1818
Query: 1356 ASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGG 1535
A N AG D +++ + +RV +K A +
Sbjct: 1819 ALNAAGRDQKLVQLSVLVPPAFRQAPRGP---------QDAVLVRVGDK--AVLSCETDA 1867
Query: 1536 DPIPNVKWTKGKWRQLNQGGRIFIHQKGDE----AKLEIRDTTKTDSGLYRCVAFNKHGE 1703
P P V W K G + + Q+ +LEI++ +D GLY C N GE
Sbjct: 1868 LPEPTVTWYK-------DGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGE 1920
Query: 1704 IESNVNLQV 1730
L V
Sbjct: 1921 AVRTFTLTV 1929
Score = 146 bits (369), Expect = 6e-35
Identities = 139/589 (23%), Positives = 230/589 (39%), Gaps = 14/589 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK G +L+C G P +SW+ + + ++ +V L SG
Sbjct: 415 VKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRL--ESPGEASSG 472
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C A + GE + VQ +PP + L V VG P+ C SGS +
Sbjct: 473 LYSCVASSPAGEAVLQYSVEVQ---VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT 529
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
+ W ++GRP ++ +Q + TL+I + +G ++C ATN G+A + + +
Sbjct: 530 IQWLQNGRPAEELAGVQVA--SQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVH 587
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFEC----------HVTGTQPIKVAWAKDNREIRSGG 689
P ++P+ + F P+ W
Sbjct: 588 GEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPT 647
Query: 690 NYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK-KLS 866
++Y L I KVD D G YTC A N G+ L + L+PP+ ++
Sbjct: 648 GIPVAY-SLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKV---LVPPNIEPGPVN 703
Query: 867 ETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGD 1046
+ V E S LE +G P V+W+K + + ++ +T + +L++++A + D
Sbjct: 704 KAV--LENASVTLECLASGVPPPDVSWFKGHQPV--SSWMGVTVSVDGRVLRIEQAQLSD 759
Query: 1047 AGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIR 1226
AG Y C SN AGS + + P + + PV V+ ++L+C+ G+
Sbjct: 760 AGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTP--VRLTCNATGAPSPT 817
Query: 1227 IQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXX 1406
+ WLK G + P+ G VL +D+G Y C A + G D
Sbjct: 818 LMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQ------- 870
Query: 1407 XXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQL 1583
V + E ++ VV + + P P + W K G+ +
Sbjct: 871 --------DVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEP 922
Query: 1584 NQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
G +H D+A L++ D+G Y C A N+ G E + NL V
Sbjct: 923 RPG----VHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNV 967
Score = 141 bits (356), Expect = 2e-33
Identities = 145/580 (25%), Positives = 227/580 (39%), Gaps = 3/580 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V+V +A L CQ G P VSW K L P + +L V + D+G
Sbjct: 2491 VNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPE--GSLRIQPVLAQDAG 2548
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y+C A NS G L V E PP+ + ++ T P + C SGS V
Sbjct: 2549 HYLCLASNSAGSDRQGRDLRVLE---PPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVV 2605
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+KDG+ L L L + + Q+ C +N +G A RL
Sbjct: 2606 WWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAH---RLYQVTV 2662
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRS-GGNYQISYLENSA 722
PP + CH TG V+W+K ++ + G Y++S S
Sbjct: 2663 HVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVS---PSG 2719
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I + G+YTC A N G A ++ + K L V
Sbjct: 2720 ALEIGQALPIHAGRYTCSARNSAG----VAHKHVFLTVQASPVVKPLPSVVRAVAEEEVL 2775
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L +G ++ W K + + + ++ L++ AS DAG Y C N A
Sbjct: 2776 LPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQ---LRIAHASPEDAGNYLCIAKNSA 2832
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GSA+ + +V+ + PPV + L ++ +EG L C RGS I W K G+ +
Sbjct: 2833 GSAMGKTRLVV---QVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG 2889
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
++ F+ +L K++ DAG Y C A N G + +T
Sbjct: 2890 AEG-KFTIQPSGELL-VKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLP--------- 2938
Query: 1443 XVDGKLFFVSEP--QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
F + P +S+R+ ++ A+ G P P + WT R + +G + ++
Sbjct: 2939 ------VFTTLPGDRSLRLGDRLWLRCAAR--GSPTPRIGWTVND-RPVTEG----VSEQ 2985
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ L+ ++ DSG Y C A N+ G ++ + V E
Sbjct: 2986 DGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKE 3025
Score = 141 bits (356), Expect = 2e-33
Identities = 146/574 (25%), Positives = 220/574 (38%), Gaps = 1/574 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTAT-YKMHFRNNVATLVFNQVDSNDSGE 188
VT+ L C G P VSW K +L + Y++ + L Q +G
Sbjct: 2677 VTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRV---SPSGALEIGQALPIHAGR 2733
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y C A NS G FLTVQ + +R V E V+ C SG +++W
Sbjct: 2734 YTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEE---EVLLPCEASGIPRPTITW 2790
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K+G + G + T L L I AG Y C A N GSA RL++ +
Sbjct: 2791 QKEGLNVATG--VSTQVLPG-GQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVV---Q 2844
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP + L + G A C G+ + W KD + + SG + + ++ S L
Sbjct: 2845 VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPV-SGAEGKFT-IQPSGEL 2902
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
+ ++ D G YTC A N VG+ L I L+ P FT + G+ L
Sbjct: 2903 LVKNLEGQDAGTYTCTAENAVGRARRRVHLTI---LVLPVFTTLPGDRSLRL-GDRLWLR 2958
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
GS + W N+ + ++ ++ LQ S D+G Y C N G
Sbjct: 2959 CAARGSPTPRIGWTVNDRPVTEG----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGR 3014
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
S + +KE P + + + + G +QL C VRG I W+K G ++ S
Sbjct: 3015 TQAVSFVHVKEA--PVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGS- 3071
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
NG+ + + + DAG Y C A N G +K V +
Sbjct: 3072 HLRHQLQNGSLTIHRTE--RDDAGRYQCLAENEMG--VAKKVVILV-------------L 3114
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F EPQ + V + G+P P ++W + + L R+ + +
Sbjct: 3115 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQA-GQPLRASRRL---RTLPDG 3170
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
L + + D+G Y CVA N G + L V
Sbjct: 3171 SLWLENVETGDAGTYDCVAHNLLGSATARAFLVV 3204
Score = 137 bits (346), Expect = 3e-32
Identities = 138/601 (22%), Positives = 228/601 (37%), Gaps = 35/601 (5%)
Frame = +3
Query: 36 LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSV 215
L C+ G P ++W+K D L PT+T ++ R L + S+D+G Y C+A N+V
Sbjct: 331 LLCEARGVPTPNITWFK-DGALLPTSTKVVYTRGG-RQLQLGRAQSSDAGVYTCKASNAV 388
Query: 216 GEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKD 395
G +T L V + V+ G PV EC G ++SW +G P+ +
Sbjct: 389 GAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAE 448
Query: 396 GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSA--------SSSARLILTEGRN 551
+ ++ + + L + + +G YSC A++P G A +L++ EG
Sbjct: 449 --SNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEG-- 504
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
L V +VG+ + C +G+ + W ++ R Q++ + H+
Sbjct: 505 -------LGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHID 557
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
+++D +G + C A NE G ++++ P + + E +S
Sbjct: 558 HVELD--HSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHS---SF 612
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALL----------------LQVKKASMG 1043
A P+ W HP + + L LQ++K +
Sbjct: 613 PAACDPPVHRGW-----GAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLR 667
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
D G+YTC +N AG + V + PP + V E + L C G P
Sbjct: 668 DEGIYTCAATNLAGE---SKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPP 724
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTX 1403
+ W K + + S + + VL + +DAG Y C ASNVAGS + +
Sbjct: 725 DVSWFKGHQPV--SSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRV 782
Query: 1404 XXXXXXXXXXXXXXVDGKLFFVSEPQSI--RVVEKTTATFIAKVGGDPIPNVKWTKG--- 1568
++ P S+ V+ T G P P + W K
Sbjct: 783 NVPPR----------------ITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNP 826
Query: 1569 ------KWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
Q+ GGR+ L + +DSG Y CVA + GE +V LQV
Sbjct: 827 VSPAGTPGLQVFPGGRV----------LTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 876
Query: 1731 N 1733
+
Sbjct: 877 H 877
Score = 127 bits (318), Expect = 5e-29
Identities = 147/583 (25%), Positives = 219/583 (37%), Gaps = 7/583 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V G L C ++G P V+W K + +A + + R L +++ +G
Sbjct: 1943 VSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGG--RLQLSRLQPAQAG 2000
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C AEN+ E + V S S R+ G V +C G P V+
Sbjct: 2001 TYTCVAENTQAEARKDFVVAVLVAPRIRS-SGVAREHHVLEGQEVRLDCEADGQPPPDVA 2059
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W KDG PL F + +L + S AG Y+C A NP G ARL
Sbjct: 2060 WLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGE---DARLHTVNV 2116
Query: 546 RNPPFFDIPLAPVDAVV---GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
PP +V GE C V G+ PI V+W KD + Q + L
Sbjct: 2117 LVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLS---QRTLLHG 2173
Query: 717 SAH-LTILKVDKGDTGQYTCYAVNEVG--KDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
S H L I KV D G +TC A + G + T Q+ + L P F V
Sbjct: 2174 SGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEF----QNDVVVVR 2229
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
G+ L G V+W K+ P + + LQ++ GD+G Y+C
Sbjct: 2230 GSLVELPCEARGVPLPLVSWMKDG---EPLLSQSL---EQGPSLQLEAVGAGDSGTYSCV 2283
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQ-HLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKA 1244
++AG A + + EP P + D T ++++ G ++L C +G+ I W K
Sbjct: 2284 AVSEAGEARRHFQLTVMEP--PHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKD 2341
Query: 1245 GREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXX 1424
G+ + + S T VL +D AG Y C A + AG+ +V
Sbjct: 2342 GQALTRLENNS----RATRVLRVRD-----AGLYTCLAESPAGAIEKSFRVRVQAPPNIV 2392
Query: 1425 XXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIF 1604
G F V V+E V +P P + W + L +
Sbjct: 2393 GPR------GPRFVVGLAPGQLVLE-------CSVEAEPAPKITWHRDGI-VLQEDAHTQ 2438
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
++G +L+ T DSG Y C A N G ++++
Sbjct: 2439 FPERGRFLQLQALSTA--DSGDYSCTARNAAGSTSVAFRVEIH 2479
Score = 124 bits (312), Expect = 2e-28
Identities = 140/568 (24%), Positives = 211/568 (37%), Gaps = 7/568 (1%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G+ ++ C + G+P I VSW K L + +H + TL ++V D+G + C
Sbjct: 2137 GELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGH--TLRISKVQLADAGIFTCV 2194
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A + G + L VQ + Q DV G V C G VSW KDG
Sbjct: 2195 AASPAGVADRNFTLQVQVPPVLEPVEFQ-NDVVVVRGSLVELPCEARGVPLPLVSWMKDG 2253
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
PL + L+ +L + +G YSC A + G A +L + E PP
Sbjct: 2254 EPLL------SQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVME---PPH 2304
Query: 561 FDIPLAPVDAVVGESADFE--CHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT- 731
+ P + + A E C GT + W KD + + + LEN++ T
Sbjct: 2305 IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL--------TRLENNSRATR 2356
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKLSETVEETEGNSFRLE 908
+L+V D G YTC A + G + ++ ++ PP+ + V LE
Sbjct: 2357 VLRVR--DAGLYTCLAESPAGAIEKSFRVRVQA---PPNIVGPRGPRFVVGLAPGQLVLE 2411
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
V + W+++ + + A+ + F LQ++ S D+G Y+C N AGS
Sbjct: 2412 CSVEAEPAPKITWHRDGIVLQEDAHTQ--FPERGRFLQLQALSTADSGDYSCTARNAAGS 2469
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
TS E P V VS + L C G + W K + P
Sbjct: 2470 ---TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRS 2526
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
G+ L + V DAG Y+C ASN AGSD +
Sbjct: 2527 PRFEILPEGS--LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPA---------- 2574
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWR---QLNQGGRIFIHQKG 1619
P ++ + T A + G P P V W K + +L QG +
Sbjct: 2575 -----IAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNA 2629
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
L + DS + CV N+ GE
Sbjct: 2630 ----LLLTAPGPQDSAQFECVVSNEVGE 2653
Score = 120 bits (300), Expect = 6e-27
Identities = 145/613 (23%), Positives = 230/613 (37%), Gaps = 37/613 (6%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVA-----TLVFNQVD 170
V +TVG A C GTP+ V+W KG + + +H + VA +L V
Sbjct: 13 VALTVGLEAG-GCGTHGTPKPQVTWRKGPS------SEPLHGQPGVAVLEEGSLFLASVS 65
Query: 171 SNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR--DVQETVGLPVVFECAVSG 344
DSG+Y C+A N VG S L V +PPS R +V G + EC +G
Sbjct: 66 PADSGDYECQATNEVGSTSRRAKLVVY---VPPSIREDGRKANVSGMAGQSLTLECDANG 122
Query: 345 SEPISVSWFKD-------------GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSC 485
+ W KD G L G LD +L+ + +G+
Sbjct: 123 FPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQPGRSGRRGA 182
Query: 486 TATNPIGSASSSARLI-----LTEGRNPPFFDIPLAP----------VDAVVGESADFEC 620
A GSA + A + P F P P V + G + +C
Sbjct: 183 QAG---GSAQTKAPWXAGLAGFEQFPTPHAFSPPAPPSVLGAGAAQEVLGLAGADVELQC 239
Query: 621 HVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKD 800
+G +V W KD + + GG + + E+ L I GD G+Y C A + G+
Sbjct: 240 WTSGVPTPQVEWTKDRQPVLPGGPH-LQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQ 298
Query: 801 SCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTA 980
+ QL + P + + V E + +L G ++ W+K+ + PT+
Sbjct: 299 ARDFQLRVHAP--PTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL-PTS 355
Query: 981 NCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP 1160
++ + LQ+ +A DAG+YTCK SN G+A + + + P P + P
Sbjct: 356 T-KVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVP--PTIEGAGGRP 412
Query: 1161 VTVS--EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKAD 1334
V G + L C RG + W G + S+ +VL + +A
Sbjct: 413 YVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLE--TDGSVLRLESPGEAS 470
Query: 1335 AGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTAT 1514
+G Y C AS+ AG + V V +L + +
Sbjct: 471 SGLYSCVASSPAGEAVLQYSV-------------EVQVPPQLLVAEGLGQVTTIVGQPLE 517
Query: 1515 FIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNK 1694
+ G P+P ++W + R + + + +G L I SGL+ C A N+
Sbjct: 518 LPCQASGSPVPTIQWLQ-NGRPAEELAGVQVASQG--TTLHIDHVELDHSGLFACQATNE 574
Query: 1695 HGEIESNVNLQVN 1733
G + V + V+
Sbjct: 575 AGTAGAEVEVSVH 587
Score = 95.5 bits (236), Expect = 2e-19
Identities = 117/517 (22%), Positives = 194/517 (37%), Gaps = 35/517 (6%)
Frame = +3
Query: 285 LRDVQETVGLPVVFECAVSGSEPISVSWFK--DGRPLKDGPNIQTSFLDNVATLNIFQTD 458
L DV TVGL C G+ V+W K PL P + ++ ++ D
Sbjct: 10 LGDVALTVGLEAG-GCGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPAD 68
Query: 459 RSFAGQYSCTATNPIGSASSSARLILTEGRNPPFF--DIPLAPVDAVVGESADFECHVTG 632
+G Y C ATN +GS S A+L++ PP D A V + G+S EC G
Sbjct: 69 ---SGDYECQATNEVGSTSRRAKLVVYV---PPSIREDGRKANVSGMAGQSLTLECDANG 122
Query: 633 TQPIKVAWAKDNREIR-----SGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGK 797
++ W KD + + +G + + + + H + D+G + + G+
Sbjct: 123 FPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLL---DEGQSLHFPRIQPGRSGR 179
Query: 798 DSCTA------------------QLNIKERLIPPSFTKKL----SETVEETEGNSFRLEG 911
A Q PP+ L ++ V G L+
Sbjct: 180 RGAQAGGSAQTKAPWXAGLAGFEQFPTPHAFSPPAPPSVLGAGAAQEVLGLAGADVELQC 239
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
+G V W K+ + P + + + +L++ + +GD G Y C + AG
Sbjct: 240 WTSGVPTPQVEWTKDRQPVLP-GGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQ 298
Query: 1092 LCTSSIVIKEPKKPPVFDQHLT-PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
+ + P P ++ + T V V E +QL C RG I W K G + S
Sbjct: 299 ARDFQLRVHAP--PTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTST 356
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ ++ G L+ +DAG Y CKASN G+ +++ +
Sbjct: 357 KVVYT--RGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRL---------DVYVPPTI 405
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW-TKGKWRQLNQGGRIFIHQKGDE 1625
+G P ++ V G P P + W +G + R+ + D
Sbjct: 406 EGA---GGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRL----ETDG 458
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGE--IESNVNLQV 1730
+ L + + SGLY CVA + GE ++ +V +QV
Sbjct: 459 SVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQV 495
>ref|NP_005520.4| basement membrane-specific heparan sulfate proteoglycan core protein
precursor [Homo sapiens].
Length = 4391
Score = 157 bits (396), Expect = 4e-38
Identities = 142/595 (23%), Positives = 238/595 (40%), Gaps = 16/595 (2%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV V VG + +L+C AG P W + + ++ A L + +D+
Sbjct: 3121 PVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDA 3180
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSR-QLRDVQETV--GLPVVFECAVSGSEP 353
G Y+C A+N++G + V + P + Q + + TV G C+ +GS
Sbjct: 3181 GTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPA 3240
Query: 354 ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
++ W K PL ++ TL I + + +GQY C AT+P G A ++ I
Sbjct: 3241 PTIHWSKLRSPLPWQHRLEGD------TLIIPRVAQQDSGQYICNATSPAGHAEAT---I 3291
Query: 534 LTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI--RSGGNYQISY 707
+ +PP+ GE+ +C GT P+ W++ + R+ ++ +
Sbjct: 3292 ILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNELLH 3351
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQL-------NIKERLIPPSFTKKLS 866
E +A D+G+Y C N+VG AQL ++ IP T +
Sbjct: 3352 FERAA--------PEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ 3403
Query: 867 ETVE-ETE--GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKAS 1037
T + ET+ G S V + + W+K ++ P + + +L+++
Sbjct: 3404 VTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDG------VLRIQNLD 3457
Query: 1038 MGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPV-TVSEGEFLQLSCHVRGS 1214
G Y C+ G A ++ +VI+ P V T V TV G ++ C G
Sbjct: 3458 QSCQGTYICQAHGPWGKAQASAQLVIQA--LPSVLINIRTSVQTVVVGHAVEFECLALGD 3515
Query: 1215 EPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSK 1394
++ W K G ++P V+ V ADAG Y C A+N AG T++S
Sbjct: 3516 PKPQVTWSKVGGHLRPG------IVQSGGVVRIAHVELADAGQYRCTATNAAG--TTQSH 3567
Query: 1395 VTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKW 1574
V +S PQ +RV + A F G P P++ W+K
Sbjct: 3568 VLLLVQALPQ--------------ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSK--- 3610
Query: 1575 RQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
G + + + L + D+G Y C A N+ G++++ +LQV ER
Sbjct: 3611 ----LDGSLPPDSRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER 3661
Score = 152 bits (385), Expect = 8e-37
Identities = 150/578 (25%), Positives = 228/578 (39%), Gaps = 9/578 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G S SL+CQ++G+P W + D + P+ T + H + L F V +D+G Y
Sbjct: 1688 VPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRH---QGSELHFPSVQPSDAGVY 1744
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV--GLPVVFECAVSGSEPI-SV 362
IC N +S L V E P ++V G V F C P ++
Sbjct: 1745 ICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTL 1804
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL-ILT 539
W + L +G + T +D L I S AG Y CT +N +A L +
Sbjct: 1805 VWTR----LHNG-KLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQA 1859
Query: 540 EGR-NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
G + P I + G+ A+F C TG+ + W GG +
Sbjct: 1860 SGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGG-----PGGQLPAKAQIH 1914
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
L + V+ D QY C A + G+ A L++ P + E + G +
Sbjct: 1915 GGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPR--VQVSPERTQVHAGRT 1972
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
RL R AG ++ W K + P A E T + L + + DAG Y C ++
Sbjct: 1973 VRLYCRAAGVPSATITWRKEGGSLPPQARSERT---DIATLLIPAITTADAGFYLCVATS 2029
Query: 1077 DAGSALCTSSIVI---KEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
AG+A +V+ + PPV + +P +V+EG+ L L+C V GS ++ W + G
Sbjct: 2030 PAGTAQARIQVVVLSASDASPPPVKIESSSP-SVTEGQTLDLNCVVAGSAHAQVTWYRRG 2088
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
+ P + S L V+ AD+G+YVC+ N GS ++ +T
Sbjct: 2089 GSLPPHTQVHGS------RLRLPQVSPADSGEYVCRVEN--GSGPKEASITVSVLHGTHS 2140
Query: 1428 XXXXXXVDGKLFFVS-EPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIF 1604
V G + EP S V E T V G V W K +GG +
Sbjct: 2141 GPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHK-------RGGSLP 2193
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNV 1718
+ + L + T DSG Y C G +E++V
Sbjct: 2194 ARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASV 2231
Score = 142 bits (357), Expect = 1e-33
Identities = 142/611 (23%), Positives = 236/611 (38%), Gaps = 26/611 (4%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+V G + L C+ AG P ++W K L P A + R ++ATL+ + + D+G
Sbjct: 1966 QVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSE---RTDIATLLIPAITTADAGF 2022
Query: 189 YICRAENSVGEVSSSTFLTV--QEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
Y+C A + G + + V PP + T G + C V+GS V
Sbjct: 2023 YLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQV 2082
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W++ G L + S L + Q + +G+Y C N G +S + +
Sbjct: 2083 TWYRRGGSLPPHTQVHGS------RLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLH 2136
Query: 543 GRN--PPFFDIP-------LAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGG 689
G + P + +P + P + V G++ D C V G +V W K GG
Sbjct: 2137 GTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHK------RGG 2190
Query: 690 NYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERL----IPPSFTK 857
+ + + + L + +V D+G+Y C+ V G + + I+ + IPP +
Sbjct: 2191 SLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIE 2250
Query: 858 KLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKAS 1037
S TV EG + L VAG V WYK + + L + +AS
Sbjct: 2251 SSSSTV--AEGQTLDLSCVVAGQAHAQVTWYKRG------GSLPARHQVRGSRLYIFQAS 2302
Query: 1038 MGDAGLYTCKVSNDAGSALCT-------SSIVIKEPKKPPVFDQHLTPVT--VSEGEFLQ 1190
DAG Y C+ SN +++ +++ P+ + P + V+EG+ L
Sbjct: 2303 PADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPI---RIEPSSSQVAEGQTLD 2359
Query: 1191 LSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVA 1370
L+C V G ++ W K G + + S +L + AD+G+YVC+ +
Sbjct: 2360 LNCVVPGQSHAQVTWHKRGGSLPVRHQTHGS------LLRLYQASPADSGEYVCRVLGSS 2413
Query: 1371 GSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPN 1550
+ VT V E S +V E T V G
Sbjct: 2414 VPLEASVLVTIEPAGSVPALGVTPTVR------IESSSSQVAEGQTLDLNCLVAGQAHAQ 2467
Query: 1551 VKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
V W K +GG + + ++L + T DSG Y C G E++V + +
Sbjct: 2468 VTWHK-------RGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTI 2520
Query: 1731 NERKKQEKIEG 1763
+R +G
Sbjct: 2521 QQRLSGSHSQG 2531
Score = 135 bits (341), Expect = 1e-31
Identities = 158/669 (23%), Positives = 256/669 (38%), Gaps = 35/669 (5%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G + L C +A ++WYK L P+ + R + QV DSGEY+C
Sbjct: 2548 GHTLDLNCLVASQAPHTITWYKRGGSL-PSRHQIVGSRLRIP-----QVTPADSGEYVCH 2601
Query: 201 AENSVGEVSSSTFLTVQEQKLP--PSFSRQLR--DVQETV--GLPVVFECAVSGSEPISV 362
N G +S +T+Q PS S +R TV G + C V+ +
Sbjct: 2602 VSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAII 2661
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W+K G L S L + Q + +G+Y C A N I + +S + ++
Sbjct: 2662 TWYKRGGSLPSRHQTHGSHL------RLHQMSVADSGEYVCRANNNIDALEASIVISVSP 2715
Query: 543 GRNPPFFDIPLAPV-------DAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
P P+ GE+ D C V G +V W K GG+
Sbjct: 2716 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHK------RGGSLPS 2769
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERL-----------IPPS 848
+ + L + V D+G+Y C + G + + I+ PP
Sbjct: 2770 HHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPI 2829
Query: 849 FTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVK 1028
+ S V EG + L+ V G V W+K N + + LL++
Sbjct: 2830 RIEPSSSRV--AEGQTLDLKCVVPGQAHAQVTWHKRG------GNLPARHQVHGPLLRLN 2881
Query: 1029 KASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKP----------PVFDQHLTPVTVSEG 1178
+ S D+G Y+C+V+ +G+ L S +V EP P P++ + + V+EG
Sbjct: 2882 QVSPADSGEYSCQVTGSSGT-LEASVLVTIEPSSPGPIPAPGLAQPIYIE-ASSSHVTEG 2939
Query: 1179 EFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKA 1358
+ L L+C V G ++ W K G + + S L V+ AD+G+YVC+A
Sbjct: 2940 QTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGS------QLRLHLVSPADSGEYVCRA 2993
Query: 1359 SNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGD 1538
++ G + S V +P S V + A+F +
Sbjct: 2994 ASGPGPEQEASFTVTVPPSEGSSYRLRSPV-----ISIDPPSSTVQQGQDASFKCLIHDG 3048
Query: 1539 PIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNV 1718
P +W+ NQ +H + + + I T ++ G YRCVA N +G +S V
Sbjct: 3049 AAP----ISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVV 3104
Query: 1719 NLQVNERKKQEKI-EGDLRAMLKKTPVLKKGAGEEEEIDIMELLKNVDPKEYEKYARMYG 1895
NL V+ + EG + + K L+ + E + P + E+ R YG
Sbjct: 3105 NLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQ--RTYG 3162
Query: 1896 ITDFRGLLQ 1922
+ D +LQ
Sbjct: 3163 LMDSHAVLQ 3171
Score = 135 bits (340), Expect = 1e-31
Identities = 138/594 (23%), Positives = 233/594 (39%), Gaps = 21/594 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VT G + L C + G V+WYK L A ++ H + L + V DSGEY
Sbjct: 2936 VTEGQTLDLNCVVPGQAHAQVTWYKRGGSL--PARHQTHG----SQLRLHLVSPADSGEY 2989
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPS--FSRQLRDVQETVGLP---------VVFECAV 338
+CRA + G ++F +PPS S +LR ++ P F+C +
Sbjct: 2990 VCRAASGPGPEQEASFTVT----VPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLI 3045
Query: 339 -SGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
G+ PIS+ W + L+D +I N + + I T S G Y C A+N G A
Sbjct: 3046 HDGAAPISLEWKTRNQELEDNVHISP----NGSIITIVGTRPSNHGTYRCVASNAYGVAQ 3101
Query: 516 SSARLILTEGRNPPFFDI-PLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
S L + PP + P PV VG++ EC G W + +
Sbjct: 3102 SVVNLSV---HGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQ 3158
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET 872
+++ A L I D G Y C A N +G ++ + + P + +E
Sbjct: 3159 RTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEE 3218
Query: 873 VEET--EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGD 1046
E T G++ L GS ++ W K + + + + L+ + + + D
Sbjct: 3219 AELTVEAGHTATLRCSATGSPAPTIHWSK----LRSPLPWQHRLEGDTLI--IPRVAQQD 3272
Query: 1047 AGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIR 1226
+G Y C ++ AG A T + ++ P +H +V GE +QL C G+ P+
Sbjct: 3273 SGQYICNATSPAGHAEATIILHVESPPYATTVPEH---ASVQAGETVQLQCLAHGTPPLT 3329
Query: 1227 IQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXX 1406
QW + G + +L F+ D+G Y C+ +N GS + +++
Sbjct: 3330 FQWSRVGSSLPGRATAR------NELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQ 3383
Query: 1407 XXXXXXXXXXXXXVDGKLFFVSEPQ-SIRVVEKTTATFIAKVGGD-----PIPNVKWTKG 1568
G L S P S V+ T +G +P+ + T+
Sbjct: 3384 GP------------PGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQL 3431
Query: 1569 KWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+W +GG++ + L I++ ++ G Y C A G+ +++ L +
Sbjct: 3432 RW--FKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVI 3483
Score = 134 bits (337), Expect = 3e-31
Identities = 141/626 (22%), Positives = 226/626 (36%), Gaps = 53/626 (8%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G++ L C + G V+W+K L H + + L + V DSGEY
Sbjct: 2738 VAEGETLDLNCVVPGQAHAQVTWHKRGGSL------PSHHQTRGSRLRLHHVSPADSGEY 2791
Query: 192 ICRAENSVGEVSSSTFLTVQEQ----------------KLPPSFSRQLRDVQETVGLPVV 323
+CR S G + +S +T++ ++ PS SR G +
Sbjct: 2792 VCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAE------GQTLD 2845
Query: 324 FECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPI 503
+C V G V+W K G N+ + L + Q + +G+YSC T
Sbjct: 2846 LKCVVPGQAHAQVTWHKRGG------NLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSS 2899
Query: 504 GSASSSARLILTEGRNP----------PFFDIPLAPVDAVVGESADFECHVTGTQPIKVA 653
G+ +S L+ E +P P + I + G++ D C V G +V
Sbjct: 2900 GTLEASV-LVTIEPSSPGPIPAPGLAQPIY-IEASSSHVTEGQTLDLNCVVPGQAHAQVT 2957
Query: 654 WAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKER 833
W K GG+ + + + L + V D+G+Y C A + G +
Sbjct: 2958 WYK------RGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQ---------- 3001
Query: 834 LIPPSFTKKLSETVEETEGNSFRLEGRVA-----------------------GSQPISVA 944
SFT TV +EG+S+RL V G+ PIS+
Sbjct: 3002 --EASFTV----TVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLE 3055
Query: 945 WYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEP 1124
W N E+ + N ++ + + G Y C SN G A ++ + P
Sbjct: 3056 WKTRNQELEDNVH----ISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGP 3111
Query: 1125 KKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAV 1304
V + PV V G+ + L C G +W + ++ ++ + AV
Sbjct: 3112 PTVSVLPEG--PVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAV 3169
Query: 1305 LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS 1484
L+ +DAG YVC A N G+ + +V G +E
Sbjct: 3170 LQISSAKPSDAGTYVCLAQNALGTAQKQVEV---------IVDTGAMAPGAPQVQAEEAE 3220
Query: 1485 IRVVEKTTATFIAKVGGDPIPNVKWTKGK----WRQLNQGGRIFIHQKGDEAKLEIRDTT 1652
+ V TAT G P P + W+K + W+ +G + I +
Sbjct: 3221 LTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLEGDTLIIPR-----------VA 3269
Query: 1653 KTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ DSG Y C A + G E+ + L V
Sbjct: 3270 QQDSGQYICNATSPAGHAEATIILHV 3295
Score = 123 bits (309), Expect = 6e-28
Identities = 139/597 (23%), Positives = 214/597 (35%), Gaps = 28/597 (4%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VT G + L C +AG+ V+WY+ L P H + + + L QV DSGEY
Sbjct: 2062 VTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPP------HTQVHGSRLRLPQVSPADSGEY 2115
Query: 192 ICRAENSVGEVSSSTFLTV-------QEQKLPPSFSRQLR----DVQETVGLPVVFECAV 338
+CR EN G +S ++V P +R +R G + C V
Sbjct: 2116 VCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVV 2175
Query: 339 SGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASS 518
G V+W K G L S L + Q + +G+Y C G +
Sbjct: 2176 PGQAHAQVTWHKRGGSLPARHQTHGSL------LRLHQVTPADSGEYVCHVVGTSGPLEA 2229
Query: 519 SARLILTEGRNP---PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGG 689
S + + P P I + G++ D C V G +V W K GG
Sbjct: 2230 SVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYK------RGG 2283
Query: 690 NYQISYLENSAHLTILKVDKGDTGQYTCYAVN--EVGKDSCTAQLNIKERLIPPSFTKKL 863
+ + + L I + D GQY C A N E P T+ +
Sbjct: 2284 SLPARHQVRGSRLYIFQASPADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPI 2343
Query: 864 ---SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKA 1034
+ + EG + L V G V W+K + + + + LL++ +A
Sbjct: 2344 RIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRG------GSLPVRHQTHGSLLRLYQA 2397
Query: 1035 SMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVT--------VSEGEFLQ 1190
S D+G Y C+V + + + I+ P +TP V+EG+ L
Sbjct: 2398 SPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALG--VTPTVRIESSSSQVAEGQTLD 2455
Query: 1191 LSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVA 1370
L+C V G ++ W K G + + S L VT AD+G+YVC+ +
Sbjct: 2456 LNCLVAGQAHAQVTWHKRGGSLPARHQVHGS------RLRLLQVTPADSGEYVCRVVGSS 2509
Query: 1371 GSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVS-EPQSIRVVEKTTATFIAKVGGDPIP 1547
G+ + VT G + V E S + T V
Sbjct: 2510 GTQEASVLVTIQQRLSGSHS------QGVAYPVRIESSSASLANGHTLDLNCLVASQAPH 2563
Query: 1548 NVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNV 1718
+ W K +GG + + ++L I T DSG Y C N G E+++
Sbjct: 2564 TITWYK-------RGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSL 2613
Score = 123 bits (309), Expect = 6e-28
Identities = 138/595 (23%), Positives = 229/595 (38%), Gaps = 31/595 (5%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+V G + L C +AG V+W+K L A +++H + L QV DSGE
Sbjct: 2447 QVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQVHG----SRLRLLQVTPADSGE 2500
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSR--------QLRDVQETVGLPVVFECAVSG 344
Y+CR S G +S +T+Q Q+L S S+ + G + C V+
Sbjct: 2501 YVCRVVGSSGTQEASVLVTIQ-QRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVAS 2559
Query: 345 SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
P +++W+K G L I S L I Q + +G+Y C +N GS +S
Sbjct: 2560 QAPHTITWYKRGGSLPSRHQIVGS------RLRIPQVTPADSGEYVCHVSNGAGSRETSL 2613
Query: 525 RLILTEGRN-------PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRS 683
++ +G P I + V G++ D C V + W K
Sbjct: 2614 -IVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYK------R 2666
Query: 684 GGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF---- 851
GG+ + + +HL + ++ D+G+Y C A N + + +++ PS
Sbjct: 2667 GGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSS 2726
Query: 852 --TKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQV 1025
+ S + EG + L V G V W+K + P+ + + L++
Sbjct: 2727 MPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSL-PSHH-----QTRGSRLRL 2780
Query: 1026 KKASMGDAGLYTCKVSNDAG----SALCT------SSIVIKEPKKPPVFDQHLTPVTVSE 1175
S D+G Y C+V +G S L T S++ + P P + V+E
Sbjct: 2781 HHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAE 2840
Query: 1176 GEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCK 1355
G+ L L C V G ++ W K G + + +L V+ AD+G+Y C+
Sbjct: 2841 GQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVH------GPLLRLNQVSPADSGEYSCQ 2894
Query: 1356 ASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGG 1535
+ +G T ++ V + ++ E S V E T V G
Sbjct: 2895 VTGSSG--TLEASVLVTIEPSSPGPIPAPGLAQPIYI--EASSSHVTEGQTLDLNCVVPG 2950
Query: 1536 DPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG 1700
V W K +GG + + ++L + + DSG Y C A + G
Sbjct: 2951 QAHAQVTWYK-------RGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPG bjct: 12136 TDQTSGKLDIEDREIKLV--RPLYSVEVMETETARFETEI-SEDDIHANWKLKGEALLQT 12192
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
C VL + G +A+NV S + K
Sbjct: 12193 PECEIKEEGKIHVLILHNCRLDQTGGVDFQAANVKSSAHLRVKPRV-------------- 12238
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
+ + + + V TATF ++ + IP + KGK +L ++ +G
Sbjct: 12239 ----IGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGK--KLEPNDKVVTRSEGRV 12292
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
L +RD D+G + A + ++ NL V E
Sbjct: 12293 HTLTLRDVKLEDAGEVQLTA----KDFKTQANLFVKE 12325
Score = 70.1 bits (170), Expect = 6e-12
Identities = 67/286 (23%), Positives = 108/286 (37%), Gaps = 34/286 (11%)
Frame = +3
Query: 636 QPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQ 815
Q +V W R++ + Y+I+Y + A + + + K D G Y C VN+ G+DS A+
Sbjct: 31639 QSTQVTWYFGVRQLENSEKYEITYEDGVATMYVKDITKFDDGTYRCKVVNDYGEDSSYAE 31698
Query: 816 LNIK----------------------ERLI--PPSFTKKLSETVEETEGNSFRLEGRVAG 923
L +K RL+ PP FT L G + R +
Sbjct: 31699 LFVKGVREVYDYYCRRTKKVKRRTDAMRLLERPPEFTLPLYNKTAYV-GENVRFGVTITV 31757
Query: 924 SQPISVAWYKNNVEIHP-TANCEITFKNNALLLQ--VKKASMGDAGLYTCKVSNDAGSAL 1094
V WYK+ +I P + TF+++ L Q + + D YT N G
Sbjct: 31758 HPEPRVTWYKSGQKIKPGDDEKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKHGEDS 31817
Query: 1095 CTSSIVIKEPKKP------PVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
C + + + P P+F + L EG+ + V G ++W K G+ +
Sbjct: 31818 CKAKLTVTLHPPPTETTLRPMFKRLLANAECHEGQSVCFEIRVSGIPAPTLKWEKDGQPL 31877
Query: 1257 KPSDRCSFSFAN-GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS 1391
L +D D G Y A+N AGS + ++
Sbjct: 31878 SLGPHIEIVHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQA 31923
Score = 69.3 bits (168), Expect = 1e-11
Identities = 92/423 (21%), Positives = 154/423 (36%), Gaps = 42/423 (9%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ V G + ++G P V+W + L A + ++ ++V + G
Sbjct: 16577 IVVHAGGVIRIIAYVSGKPPPTVTWSMNERALPQEAAIETTAISS--SMVIKNCQRSHQG 16634
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y A+N GE + + V DV VG+P + + + S ++
Sbjct: 16635 VYSLLAKNEGGERKKTIIVDVL-------------DVPGPVGIPFLSDNLTNDS--CKLT 16679
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WF P DG + T+++ + + DR + T T + L +G
Sbjct: 16680 WFS---PEDDGGSPITNYV-----IQKREADRRAWTPVTYTVTRQNATVQG-----LIQG 16726
Query: 546 RN-------------PPFFDIPLAPVD----AVVGESADFECHVTGTQPIKVAWAKDNRE 674
++ PF + P A V V D E + + W N
Sbjct: 16727 KSYFFRIAAENSIGMGPFVETPNALVIRDPITVPERPEDLEVKEVTKNTVSLTW---NPP 16783
Query: 675 IRSGGNYQISYLENSAHL------------------TILKVDKGDTGQYTCYAVNEVGKD 800
GG+ I+Y+ S + T+ + +GDT +Y AVN VG+
Sbjct: 16784 KYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQG 16843
Query: 801 S---CTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIH 971
CT + K+ L PP+ + + G SF L GR +G + W+K+ ++
Sbjct: 16844 KPSFCTKPITCKDELAPPTLDLDFRDKLTVRVGESFALTGRYSGKPKPKIDWFKDEADVL 16903
Query: 972 PTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS--ALCTSSIVIK--EPKKPPV 1139
I L L+ KA D+G Y V N GS C ++V + P P +
Sbjct: 16904 EDDRTHIKTTPTTLALEKTKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVI 16963
Query: 1140 FDQ 1148
FD+
Sbjct: 16964 FDE 16966
Score = 69.3 bits (168), Expect = 1e-11
Identities = 94/408 (23%), Positives = 160/408 (39%), Gaps = 35/408 (8%)
Frame = +3
Query: 48 LAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVS 227
+ G P V W + + A+ + ++ LV V+ DSG+YI ENS G S
Sbjct: 21927 IKGRPAPEVKWAREHGESLDKASIES--TSSYTLLVVGNVNRFDSGKYILTVENSSG--S 21982
Query: 228 SSTFLTVQEQKLP-PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPN 404
S F+ V+ P P + ++++V +T ++++W PL DG +
Sbjct: 21983 KSAFVNVRVLDTPGPPQNLKIKEVTKT---------------SVTLTWEP---PLLDGGS 22024
Query: 405 IQTSFLDNVATLNIFQTDRSFAGQYSCTATN---------PIGSASSSARLILTEGRNPP 557
++ I + S YS ATN + S +L E N
Sbjct: 22025 KIKNY--------IVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAE--NEY 22074
Query: 558 FFDIPLAPVDAVVGESADFEC-HVTGTQ----PIKVAWAKDNREIRSGGNYQISYLENS- 719
+P ++V +T T + ++W K + GG+ + Y+
Sbjct: 22075 GIGLPAETAESVKASERPLPPGKITLTDVTRNSVSLSWEKPEHD---GGSRILGYIVEMQ 22131
Query: 720 ---------------AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI----KERLIP 842
TI + +G+ + A NE G S QL++ K+ +IP
Sbjct: 22132 SKGSDRWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGI-SDPRQLSVPVIAKDLVIP 22190
Query: 843 PSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQ 1022
P+F K L T G +++ G P +V W+K+++ + T N LL
Sbjct: 22191 PAF-KLLFNTFTVLAGEDLKIDVPFIGRPPPAVTWHKDDIPLKQTTRVNAESTENNSLLT 22249
Query: 1023 VKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVT 1166
+K+A D G YT K++N AG A T ++++ + PP + VT
Sbjct: 22250 IKEACREDVGHYTVKLTNSAGEATETLNVIVLDKPGPPTGPVKMDEVT 22297
Score = 67.0 bits (162), Expect = 5e-11
Identities = 150/767 (19%), Positives = 253/767 (32%), Gaps = 173/767 (22%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHF-RNNVATL----------- 152
++ G + C+++G P ++WYK ++R Y+M F ++ A+L
Sbjct: 1303 RILEGMGVTFHCKMSGYPLPKIAWYKDGKRIRHGERYQMDFLQDGRASLRIPVVLPEDEG 1362
Query: 153 VFNQVDSNDSGEYICRAENSV---GEVSSSTFLTVQEQ-----------------KLPPS 272
++ SN G IC + V S+ T++ E ++ P+
Sbjct: 1363 IYTAFASNIKGNAICSGKLYVEPAAPFSAPTYMPTPEAVSRIRSVSPRSLSRSPIRMSPA 1422
Query: 273 FS----------------------RQLRDVQET----------VGLPVVFECA------- 335
S R+L + E+ V P F+C
Sbjct: 1423 MSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPASFKCLEGQTARF 1482
Query: 336 ---VSGSEPISVSWFKDGRPL-KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPI 503
V G WF +G+ + D + D +L I S +G+++ A N
Sbjct: 1483 DLKVVGRPMPETFWFHNGQQIVNDYTHKVVIKEDGTQSLIIVPASPSDSGEWTVVAQNRA 1542
Query: 504 GSASSSARLIL--TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI 677
G ++ S L + E + P F L V+ G + + TG + W K N +I
Sbjct: 1543 GKSTISVTLTVEAVEHQIKPAFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLK-NSDI 1601
Query: 678 RSGGNYQISYLENSAHLTILKVDK---GDTGQYTCYAVNEVGKDSCTAQLNI-------- 824
Y +E + LK+D D+ YT A+N+ G+D+ ++N+
Sbjct: 1602 IVPHKYPRIRIEGTRGEAALKIDSIISQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPE 1661
Query: 825 -----------------------------------------KERLIPPSFTKKLSETVEE 881
KE+ P F KKL+ +
Sbjct: 1662 PERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLK 1721
Query: 882 TEGNS-FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
G + F G + V W + + + + L A D+G+
Sbjct: 1722 RFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGAAYSRDSGVI 1781
Query: 1059 TCKVSNDAGSALCTSSIVIKEPK------------------------------------- 1127
TC+ +N G+ ++++++K+ K
Sbjct: 1782 TCRATNKYGTDHTSATLIVKDEKSLVEESQLPDGKKGLQRIEELERMAHEGALTGVTTDQ 1841
Query: 1128 ---KPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGT 1298
+ P PV V EGE + C V G ++ W G+ I+ S R + +G
Sbjct: 1842 KEKQKPDIVLFPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY-DGI 1900
Query: 1299 AVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEP 1478
L+ D D G+ A N G K K+ F V EP
Sbjct: 1901 HYLDIVDCKSYDTGEVKVTAENPEGVTEHKVKLEIQQREDFRSVLRRAPEPKPEFHVHEP 1960
Query: 1479 QSIRV-VEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTK 1655
++ V+K D + TK + +L + RI H+K E E+R K
Sbjct: 1961 GKLQFEVQKV----------DRPVDTSETK-EVVKLKRAERI-THEKVSEESEELRSKFK 2008
Query: 1656 --TDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKT 1790
T+ G Y E+ +++ RKK E E +LKKT
Sbjct: 2009 RRTEEGYY-----------EAITAVELKSRKKDESYE----ELLKKT 2040
Score = 66.2 bits (160), Expect = 9e-11
Identities = 58/201 (28%), Positives = 82/201 (40%), Gaps = 2/201 (0%)
Frame = +3
Query: 1134 PVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS--DRCSFSFANGTAVL 1307
P+F Q L V V EG HV GS + W + G+ I S SF++G A L
Sbjct: 6 PMFTQPLQSVVVLEGSTATFEAHVSGSPVPEVSWFRDGQVISTSTLPGVQISFSDGRARL 65
Query: 1308 EFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSI 1487
VTKA++G Y +A+N +G TS +++ F QS+
Sbjct: 66 MIPAVTKANSGRYSLRATNGSGQATSTAELLVTAETAPPN------------FSQRLQSM 113
Query: 1488 RVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSG 1667
V + + +V G P P VK+ + ++ I Q+GD L I + DSG
Sbjct: 114 TVRQGSQVRLQVRVTGIPTPVVKFYR-DGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSG 172
Query: 1668 LYRCVAFNKHGEIESNVNLQV 1730
Y A N G S L V
Sbjct: 173 TYSVNATNSVGRATSTAELVV 193
Score = 65.1 bits (157), Expect = 2e-10
Identities = 126/622 (20%), Positives = 224/622 (36%), Gaps = 43/622 (6%)
Frame = +3
Query: 3 PVKVTVGD----SASLQCQL----AGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVF 158
P KVT+ D SASL + G+ +G Y + + + T + + + V V
Sbjct: 24259 PGKVTLTDVSQTSASLMWEKPEHDGGSRILG---YVVEMQPKGTEKWSVVAESKVCNAVV 24315
Query: 159 NQVDSNDSGEYICRAENSVGEVSSSTF---LTVQEQKLPPSFSRQLRDVQETVGLPVVFE 329
+ + S ++ +A N G+ + ++ + PSF G + E
Sbjct: 24316 SGLSSGQEYQFRVKAYNEKGKSDPRVLGIPVIAKDLTIQPSFKLPFNTYSVQAGEDLKIE 24375
Query: 330 CAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGS 509
V G +SW KDG PLK + L+I ++ + G+YS TATN G+
Sbjct: 24376 IPVIGRPRPKISWVKDGEPLKQTTRVNVEETATSTILHIKESSKDDFGKYSVTATNSAGT 24435
Query: 510 ASSSARLILTEGRNPPFFDIPLAPVDA-VVGESADFECHVTGTQPIKVAWAKDNREIRSG 686
A+ + +I+ E PP + V A V S + + G Q + + R+ +
Sbjct: 24436 ATENLSVIVLEKPGPPVGPVKFDEVSADFVVISWEPPAYTGGCQISN--YIVEKRDTTTT 24493
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDS------CTAQLNIKERLIPP- 845
+S + I K+ G Q+ +A N GK + Q KE P
Sbjct: 24494 NWQMVSATVARTTIKISKLKTGTEYQFRIFAENRYGKSTPLDSKPVVVQYPFKEPGPPGT 24553
Query: 846 ------SFTKKLSETVEETEGNSFRLEG-RVAGSQPISVAWYK-NNVEIHPTANCEITFK 1001
S + L + E ++ G + + S+ W K N + I T + T
Sbjct: 24554 PFVTSISKDQMLVQWHEPVNDGGSKVTGYHLEQKEKNSILWVKLNKIPIQDT-KFKTTGL 24612
Query: 1002 NNALLLQVKKASMGDAGL------YTCKVSND--------AGSALCTSSIVIKEPKKPPV 1139
+ L + + ++ G+ C V+ D + +S+ +K K PV
Sbjct: 24613 DEGLEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIVITRNSVTLK--WKKPV 24670
Query: 1140 FD--QHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEF 1313
+D +T V + + +W+KA + + EF
Sbjct: 24671 YDGGSKITGYIVEKKDLPD------------GRWMKASFTNVVETEFTVTGLVEDQRYEF 24718
Query: 1314 KDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRV 1493
+ + + +A D + S +G+ T++ ++ V FV E
Sbjct: 24719 RVIAR-NAADNFSEPSESSGAITARDEIDAPNASLDPKYRDVIIVHAGETFVLE------ 24771
Query: 1494 VEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLY 1673
A + G PIP++ W+K R+ I + L ++D +TD G Y
Sbjct: 24772 ---------ADIRGKPIPDIIWSKDGNELEETAARMEIKSTLQKTTLIVKDCIRTDGGQY 24822
Query: 1674 RCVAFNKHGEIESNVNLQVNER 1739
N G + ++V +R
Sbjct: 24823 TLKLSNVGGTKTIPITVKVLDR 24844
Score = 63.9 bits (154), Expect = 4e-10
Identities = 46/186 (24%), Positives = 80/186 (43%), Gaps = 2/186 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V +G++A L CQ+ G P + WY+ +L + YKM TL + D G
Sbjct: 30585 VTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTDEQEDEG 30644
Query: 186 EYICRAENSVGEVSSSTFLTVQ-EQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
Y C A N VGEV SS+ L +Q + P + + VG + G ++
Sbjct: 30645 VYTCVATNEVGEVESSSKLLLQAAPQFHPGYPLK-EKYYGAVGSTLRLHVMYIGRPVPAM 30703
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDR-SFAGQYSCTATNPIGSASSSARLILT 539
+WF + L++ I ++ L + R + AG+Y +N G+ ++ + +
Sbjct: 30704 TWFHGQKLLQNSEKITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNAFGTVDATLDVEIQ 30763
Query: 540 EGRNPP 557
+ + P
Sbjct: 30764 DKPDKP 30769
Score = 62.4 bits (150), Expect = 1e-09
Identities = 80/356 (22%), Positives = 130/356 (36%), Gaps = 10/356 (2%)
Frame = +3
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W K+ D I+ N L+I DR+ AG+Y N GS S+ + +
Sbjct: 24099 ITWSKEEGEFTDKVQIEKGI--NFTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV- 24155
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAK------DNREIRSGGNYQI 701
D P P + V E + PI AK D RE +
Sbjct: 24156 -------LDTPGPPQNLAVKEVRKDSVLLVWEPPIIDGGAKVKNYVIDKRESTRKAYANV 24208
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET-VE 878
S N + + +G + A NE G T + + PPS K++ T V
Sbjct: 24209 SSKCNKTSFRVENLTEGAIYYFRVMAENEFGVGVPTETSDAVKASEPPSPPGKVTLTDVS 24268
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
+T + + G I Y ++ T + ++ V S G +
Sbjct: 24269 QTSASLMWEKPEHDGGSRI--LGYVVEMQPKGTEKWSVVAESKVCNAVVSGLSSGQEYQF 24326
Query: 1059 TCKVSNDAGSA---LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRI 1229
K N+ G + + ++ K+ P F +V GE L++ V G +I
Sbjct: 24327 RVKAYNEKGKSDPRVLGIPVIAKDLTIQPSFKLPFNTYSVQAGEDLKIEIPVIGRPRPKI 24386
Query: 1230 QWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
W+K G +K + R + + +L K+ +K D G Y A+N AG+ T V
Sbjct: 24387 SWVKDGEPLKQTTRVNVEETATSTILHIKESSKDDFGKYSVTATNSAGTATENLSV 24442
Score = 57.4 bits (137), Expect = 4e-08
Identities = 106/509 (20%), Positives = 194/509 (38%), Gaps = 54/509 (10%)
Frame = +3
Query: 36 LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSV 215
L+ + G P VSW KG+ L + TLV +D+G+Y +N
Sbjct: 20045 LKIPIKGKPAPSVSWKKGEDPLATDTRVSVESTAVNTTLVVYDCQKSDAGKYTITLKNVA 20104
Query: 216 GEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKD 395
G + + V + P+ P+ F+ +E +++ W G P D
Sbjct: 20105 GTKEGTLSIKVVGKPGIPTG-------------PIKFDEVT--AEAMTLKW---GPPKDD 20146
Query: 396 GPNIQTSFL----DNV-------------ATLNIFQTDRSFAGQYSCTATNP--IGSASS 518
G + T+++ D+V T + + + +A N +G
Sbjct: 20147 GGSEITNYVLEKRDSVNNKWVTCASAVQKTTFRVTRLHEGIEYTFRVSAENKYGVGEGLK 20206
Query: 519 SARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQ 698
S ++ ++P FD+P AP + + +T T P K + Y
Sbjct: 20207 SEPIV---AKHP--FDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPIT-------GYH 20254
Query: 699 ISYLENSAHL--------------TILKVDKGDTGQYTCYAVN--EVGKDSCTAQLNIK- 827
I + E ++ L + + +G ++ A+N VGK S ++ +
Sbjct: 20255 IEFKERNSLLWKRANKTPIRMKDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVAL 20314
Query: 828 ERLIPPSFTKKLSET--------VEETEGNSFRLEGRVAGSQPI-SVAWYK-NNVEIHPT 977
+ + PP + +S T E +L G + + + S +W K N+V +
Sbjct: 20315 DPIDPPGKPEVISVTRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNV--- 20371
Query: 978 ANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS----ALCTSSIVIKEPKKPP--V 1139
+C T V G + + N AG+ + T +I+ K+ + P V
Sbjct: 20372 PDCAFT---------VTDLVEGGKYEFRIRAKNTAGAISAPSESTGTIICKDEYEAPTIV 20422
Query: 1140 FDQHLTP-VTVSEGEFLQLSC-HVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEF 1313
D + +TV G+ + LS + G + W +AG++I+PSD + +++L
Sbjct: 20423 LDPTIKDGLTVKAGDSIVLSAISILGKPLPKSSWSRAGKDIRPSDIAQITSTPTSSMLTV 20482
Query: 1314 KDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
K T+ DAG+Y A+N G+ KV+
Sbjct: 20483 KYATRKDAGEYTITATNPFGTKEEHVKVS 20511
Score = 57.4 bits (137), Expect = 4e-08
Identities = 61/240 (25%), Positives = 91/240 (37%), Gaps = 16/240 (6%)
Frame = +3
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLP--------PSFSRQLRDVQETVGLPVVFECAVS 341
E+ + EN GE S + + E P P F +LR++ C V+
Sbjct: 30939 EFRVKCENLGGE---SEWSEISEPVTPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVT 30995
Query: 342 GSEPISVSWFKDGRPL-KDGPNIQTS-FLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
G V W++ G+ + DG + F L I A Y ATN GS S
Sbjct: 30996 GHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVS 31055
Query: 516 SSARLILTEGRNPPFFDIP-----LAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIR 680
+A L E P +P + V A+ GE + +G + W K I
Sbjct: 31056 GTASL---EVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLID 31112
Query: 681 SGGNYQISYLENSAHLTILK-VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK 857
+ G+YQ+ + L V++ D G Y A N G D T +L++ + PP K
Sbjct: 31113 NNGHYQVIVTRSFTSLVFSNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVK 31172
Score = 56.6 bits (135), Expect = 7e-08
Identities = 81/362 (22%), Positives = 129/362 (35%), Gaps = 15/362 (4%)
Frame = +3
Query: 336 VSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
VSG P +V+W + R L I+T+ + + ++ I RS G YS A N G
Sbjct: 16591 VSGKPPPTVTWSMNERALPQEAAIETTAISS--SMVIKNCQRSHQGVYSLLAKNEGGERK 16648
Query: 516 SSARLILTEGRNPPFFDIPLAPVDAVVGESAD---FECHVTGTQPIKVAWAKDNREIRSG 686
+ + + + P IP D + +S F G PI + RE
Sbjct: 16649 KTIIVDVLDVPGP--VGIPFLS-DNLTNDSCKLTWFSPEDDGGSPI-TNYVIQKREADRR 16704
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLN---IKERLIPPSFTK 857
++Y + T+ + +G + + A N +G N I++ + P +
Sbjct: 16705 AWTPVTYTVTRQNATVQGLIQGKSYFFRIAAENSIGMGPFVETPNALVIRDPITVPERPE 16764
Query: 858 KLS--ETVEETEGNSFRLEGRVAGSQPISVAWYKNNV---EIHPTANCEITFKNNALLLQ 1022
L E + T ++ GS+ I+ + + H N + +
Sbjct: 16765 DLEVKEVTKNTVSLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYT---- 16820
Query: 1023 VKKASMGDAGLYTCKVSNDAGS---ALCTSSIVIKEPKKPPVFDQHLTP-VTVSEGEFLQ 1190
VK GD Y N G + CT I K+ PP D +TV GE
Sbjct: 16821 VKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLDLDFRDKLTVRVGESFA 16880
Query: 1191 LSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVA 1370
L+ G +I W K ++ DR T LE ++D+G Y N
Sbjct: 16881 LTGRYSGKPKPKIDWFKDEADVLEDDRTHIKTTPTTLALEKTKAKRSDSGKYCVVVENST 16940
Query: 1371 GS 1376
GS
Sbjct: 16941 GS 16942
Score = 56.6 bits (135), Expect = 7e-08
Identities = 41/136 (30%), Positives = 61/136 (44%), Gaps = 3/136 (2%)
Frame = +3
Query: 777 AVNEVGKDS-CTAQLNIKERLIPP--SFTKKLSETVEETEGNSFRLEGRVAGSQPISVAW 947
A + K S T + K+ + P S K +T+ G +FRLE V G ++ W
Sbjct: 23643 AAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW 23702
Query: 948 YKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPK 1127
+ + EI +A CEI + LL VK A D G Y + SN AGS ++ + +
Sbjct: 23703 LRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP 23762
Query: 1128 KPPVFDQHLTPVTVSE 1175
PP +T VT +
Sbjct: 23763 GPPEGPVQVTGVTAEK 23778
Score = 56.2 bits (134), Expect = 9e-08
Identities = 102/497 (20%), Positives = 183/497 (36%), Gaps = 31/497 (6%)
Frame = +3
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
G +V+W KDG+ L++ + + V TL+I + R G Y +N GS +
Sbjct: 25463 GRPQATVAWKKDGQVLRETTRVNVASSKTVTTLSIKEASREDVGTYELCVSNTAGSITVP 25522
Query: 522 ARLILTEGRNPPFFDIPLAPVDAVVGESA---------DFECHVTGTQPIKVAWAKDNRE 674
+I+ + PP P+ +D V ++ D C ++ + + RE
Sbjct: 25523 ITVIVLDRPGPPG---PIR-IDEVSCDNVSISWNPPEYDGGCQISN-------YIVEKRE 25571
Query: 675 IRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI--KERLIPPS 848
S +S + I+++ G Q+ A N GK S + + + PP
Sbjct: 25572 TTSTTWQVVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPG 25631
Query: 849 --FTKKLSETVEETEGNSFRLEGRVAGSQPI----------SVAWYKNNVEIHPTANCEI 992
T K+ + T S+++ GSQ I S+ W K N + ++
Sbjct: 25632 PPGTPKVVHATKSTMVVSWQVPVNDGGSQVIGYHLEYKERSSILWSKANKVLIADTQMKV 25691
Query: 993 TFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVS 1172
+ + L+ + + + AG+ C S C + ++P PP +T +T
Sbjct: 25692 SGLDEGLMYEYRVYAENIAGIGKC-------SKAC-EPVPARDPCDPP-GQPEVTNIT-- 25740
Query: 1173 EGEFLQLSCHVRGSEP-----IRIQWLKAGREIKPSDR---CSFSFANGTAVLEFKDVTK 1328
+ S ++ S+P +I R P R C+F+ T E ++T+
Sbjct: 25741 -----RKSVSLKWSKPRYDGGAKITGYIVERRELPDGRWLKCNFTNVQET-YFEVTELTE 25794
Query: 1329 ADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTT 1508
++ A N A S + S+ T +D K V I V
Sbjct: 25795 DQRYEFRVFARNAADSVSEPSESTGPITVKDDVEAPRIMMDVKFRDV-----IIVKAGEV 25849
Query: 1509 ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAF 1688
A + G P+P + W K ++ + + I L ++D + D+G Y
Sbjct: 25850 LKINADIAGRPLPVISWAK-DGVEIEERAKTEIVSTDYTTTLTVKDCVRRDTGQYVLTLK 25908
Query: 1689 NKHGEIESNVNLQVNER 1739
N G VN +V ++
Sbjct: 25909 NVAGTRTMAVNCKVLDK 25925
Score = 55.8 bits (133), Expect = 1e-07
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 3/109 (2%)
Frame = +3
Query: 240 LTVQEQKLPP--SFSRQLRDVQET-VGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQ 410
+T+ + +PP S +++ + G V + V G +VSW KD P+K I+
Sbjct: 19327 VTILAENVPPRIELSVEMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDTTPIKQAEGIK 19386
Query: 411 TSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
+ N+ TL +F +R +G Y+ TA N GS S++ +L + + PP
Sbjct: 19387 MAMKRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPP 19435
Score = 55.1 bits (131), Expect = 2e-07
Identities = 84/397 (21%), Positives = 148/397 (37%), Gaps = 18/397 (4%)
Frame = +3
Query: 246 VQEQKLPPSF---SRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTS 416
V+++ PP + R+ VG + + G V+W K+ R I +
Sbjct: 17252 VKDRLEPPELILDANMAREQHIRVGDTLRLSAIIKGVPFPKVTWKKEDREAPTKAQIDVT 17311
Query: 417 FLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVV 596
+ + L I G YS T NP G+ + S ++++ D P P D V
Sbjct: 17312 PVGS--KLEIRNAAHEDGGIYSLTVENPAGTKTVSVKVLV--------LDKPGPPRDLEV 17361
Query: 597 GESADFECHVTGTQPIK------VAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDT 758
E C++T +P+ + + +++ + +S + +G+
Sbjct: 17362 SEIRKDSCYLTWKEPLDDGGSVVTNYVVERKDVATAQWSPLSTTSKKKSHMAKHLTEGNQ 17421
Query: 759 GQYTCYAVNEVGKD---SCTAQLNIKERLIPPSFTKKLSET-VEETEGNSFRLEGRVAGS 926
+ A N+ G+ + + L PP K L V++TE + + G
Sbjct: 17422 YLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGG 17481
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS 1106
PI+ + E T KN L V G + K N G L ++
Sbjct: 17482 SPITGYLVEYQEEGDKDWIKFKTVKN--LDCVVTGLQQGKTYRFRVKAENIIGLGLPDTT 17539
Query: 1107 IVIKEPKK--PPVFD---QHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
I I+ +K PP + + + + V G ++ +RG +W G EIK D
Sbjct: 17540 IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGTEIKTDDH 17599
Query: 1272 CSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
+ + ++VL K+ + D G+Y SN AG+ T
Sbjct: 17600 YTVETDSFSSVLTIKNCLRKDTGEYQLTVSNAAGTKT 17636
Score = 55.1 bits (131), Expect = 2e-07
Identities = 77/366 (21%), Positives = 133/366 (36%), Gaps = 12/366 (3%)
Frame = +3
Query: 336 VSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
+ G V W ++ D +I+++ + L + +R +G+Y T N GS S
Sbjct: 21927 IKGRPAPEVKWAREHGESLDKASIEST--SSYTLLVVGNVNRFDSGKYILTVENSSGSKS 21984
Query: 516 SSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI---RSG 686
+ N D P P + + E +T P+ +K I R
Sbjct: 21985 AFV--------NVRVLDTPGPPQNLKIKEVTKTSVTLTWEPPLLDGGSKIKNYIVEKRES 22036
Query: 687 GNYQISYLENSAHLTILKVDKGDTG---QYTCYAVNE--VGKDSCTAQ-LNIKERLIPPS 848
S + + H T KVD+ G + A NE +G + TA+ + ER +PP
Sbjct: 22037 TRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPG 22096
Query: 849 FTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVK 1028
L++ + S+ GS+ + + A C A + +
Sbjct: 22097 KIT-LTDVTRNSVSLSWEKPEHDGGSRILGYIVEMQSKGSDRWATCATVKVTEATITGLI 22155
Query: 1029 KASMGDAGLYTCKVSNDAGSA---LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSC 1199
+ G+ + N+ G + + ++ K+ PP F TV GE L++
Sbjct: 22156 Q---GEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKIDV 22212
Query: 1200 HVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSD 1379
G P + W K +K + R + ++L K+ + D G Y K +N AG
Sbjct: 22213 PFIGRPPPAVTWHKDDIPLKQTTRVNAESTENNSLLTIKEACREDVGHYTVKLTNSAGEA 22272
Query: 1380 TSKSKV 1397
T V
Sbjct: 22273 TETLNV 22278
Score = 54.3 bits (129), Expect = 3e-07
Identities = 91/426 (21%), Positives = 154/426 (36%), Gaps = 41/426 (9%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
+ VGD+ L + G P V+W K D + A ++ + L D G Y
Sbjct: 17273 IRVGDTLRLSAIIKGVPFPKVTWKKEDREAPTKA--QIDVTPVGSKLEIRNAAHEDGGIY 17330
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
EN G + S + V ++ PP RD+ E + + ++W
Sbjct: 17331 SLTVENPAGTKTVSVKVLVLDKPGPP------RDL----------EVSEIRKDSCYLTWK 17374
Query: 372 KDGRPLKDGPNIQTSFL---DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+ PL DG ++ T+++ +VAT Q+S +T S LTE
Sbjct: 17375 E---PLDDGGSVVTNYVVERKDVAT-----------AQWSPLSTT--SKKKSHMAKHLTE 17418
Query: 543 GRN-------------PPFFDIPLAPVDAV-----VGESADFECHVTGTQPIKVAWAKDN 668
G PF + P P+ A+ G D + + W K +
Sbjct: 17419 GNQYLFRVAAENQYGRGPFVETP-KPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPD 17477
Query: 669 REIRSGGN----YQISYLEN------------SAHLTILKVDKGDTGQYTCYAVNEVGKD 800
R+ GG+ Y + Y E + + + +G T ++ A N +G
Sbjct: 17478 RD---GGSPITGYLVEYQEEGDKDWIKFKTVKNLDCVVTGLQQGKTYRFRVKAENIIGLG 17534
Query: 801 --SCTAQLNIKERLIPPS--FTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEI 968
T + +E+L+PPS KL E + G + R + G + W + EI
Sbjct: 17535 LPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGTEI 17594
Query: 969 HPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQ 1148
+ + + + +L +K D G Y VSN AG+ + + + PP
Sbjct: 17595 KTDDHYTVETDSFSSVLTIKNCLRKDTGEYQLTVSNAAGTKTVAVHLTVLDVPGPPTGPI 17654
Query: 1149 HLTPVT 1166
++ VT
Sbjct: 17655 NILDVT 17660
Score = 53.5 bits (127), Expect = 6e-07
Identities = 110/562 (19%), Positives = 206/562 (36%), Gaps = 34/562 (6%)
Frame = +3
Query: 147 TLVFNQVDSNDSGEYICRAENSVG-----EVSSSTFLTVQEQKLPPS-----FSRQLRDV 296
T ++ N E+ +A+N G E SS ++E ++ P+ + QL +
Sbjct: 28645 TFTVERLVENTEYEFRVKAKNDAGYSEPREAFSSVI--IKEPQIEPTADLTGITNQL--I 28700
Query: 297 QETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQ 476
G + +SG V+W + LK+ + + + TL + + R +G+
Sbjct: 28701 TCKAGSTFTIDVPISGRPAPKVTWKLEEMRLKETDRMSIATTKDRTTLTVKDSMRGDSGR 28760
Query: 477 YSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAW 656
Y T N G + + +++ P I ++ V A C ++ T+P
Sbjct: 28761 YFLTLENTAGVKTFTITVVVIGRPGPVTGPIEVSSVSAE-------SCVLSWTEPKDDGG 28813
Query: 657 AKDNR---EIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNE-----VGKDSCTA 812
+ E R G + +S T +KV + C+ V+ V K +
Sbjct: 28814 TEITNYIVEKRESGTTAWQLINSSVKRTQIKVTHLTKYKEYCFRVSSENRFGVSKPLESV 28873
Query: 813 QLNIKERLIPPSFTKKLSETVEETEGNSFRLE-------GRVAG-----SQPISVAWYKN 956
+ + +PPS + S R E ++ G + ++ W K
Sbjct: 28874 PIVAEHPFVPPSAPTRPEVYYVSANAMSIRWEEPYHDGGSKIVGYWVEKKERNTILWVKE 28933
Query: 957 NVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 1136
N N ++T L Q + ++ AG+ + ++ + I+ + P PP
Sbjct: 28934 NKVPCLECNYKVTGLVEGLEYQFRTYALNAAGV--------SKASEASRPIMAQNPVDPP 28985
Query: 1137 VFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLE-F 1313
+ +T VT S + + G + + ++ + + + N T V + F
Sbjct: 28986 GRPE-VTDVTRSTVSLIWSAPVYDGGSKV-VGYIIERKPVSEVGDGRWLKCNYTIVSDNF 29043
Query: 1314 KDVTKADAGD---YVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS 1484
VT GD + A N AG + S+ T +D +L +
Sbjct: 29044 FTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARL----QGDL 29099
Query: 1485 IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDS 1664
+ + + A VGG P P + WTKG ++L+ +I + G A I+ ++DS
Sbjct: 29100 VTIRAGSDLVLDAAVGGKPEPKIIWTKGD-KELDLCEKISLQYTGKRATAVIKYCDRSDS 29158
Query: 1665 GLYRCVAFNKHGEIESNVNLQV 1730
G Y N G +V ++V
Sbjct: 29159 GKYTLTVKNASGTKSVSVMVKV 29180
Score = 53.1 bits (126), Expect = 8e-07
Identities = 30/87 (34%), Positives = 43/87 (49%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G + L + G P VSW K T ++ KM + N+ TL V+ DSG+Y
Sbjct: 19350 VKAGTNVCLDATVFGKPMPTVSWKKDTTPIKQAEGIKMAMKRNLCTLELFSVNRKDSGDY 19409
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPS 272
AENS G S++ L V ++ PP+
Sbjct: 19410 TITAENSSGSKSATIKLKVLDKPGPPA 19436
Score = 53.1 bits (126), Expect = 8e-07
Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 2/125 (1%)
Frame = +3
Query: 807 TAQLNIKERLIPP--SFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTA 980
T + ++ + PP S K +TV G SF+++ + G + W K + E+ TA
Sbjct: 22572 TGAITARDEVEPPRISMDPKYRDTVVVQAGESFKIDADIYGKPIPTTQWVKGDQELSSTA 22631
Query: 981 NCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP 1160
EI + A L VK A D+G Y K N AG T ++ + + PP ++
Sbjct: 22632 RLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGEKSVTINVKVLDRPGPPEGPVAISG 22691
Query: 1161 VTVSE 1175
VT +
Sbjct: 22692 VTAEK 22696
Score = 53.1 bits (126), Expect = 8e-07
Identities = 60/254 (23%), Positives = 105/254 (41%), Gaps = 23/254 (9%)
Frame = +3
Query: 474 QYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVA 653
Q+ A N G +S S +P F + ++PVD + D+ VT + I +
Sbjct: 27871 QFRVYAENSAGLSSPS---------DPSKFTLAVSPVDPP--GTPDY-IDVT-RETITLK 27917
Query: 654 WAKDNREIRSGGNYQISYL-----------------ENSAHLTILKVDKGDTGQYTCYAV 782
W N +R GG+ ++Y + T+ + GD ++ A
Sbjct: 27918 W---NPPLRDGGSKIVAYSIEKRQGSDRWVRCNFTDVSECQYTVTGLSPGDRYEFRIIAR 27974
Query: 783 NEVGKDSCTAQ----LNIKERLIPPS--FTKKLSETVEETEGNSFRLEGRVAGSQPISVA 944
N VG S +Q + ++ +PP+ F + + + G+S R++ V G V
Sbjct: 27975 NAVGTISPPSQSSGLIMTRDENVPPTVEFGPEYFDGLVIKSGDSLRIKALVQGRPVPRVT 28034
Query: 945 WYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEP 1124
W+K+ VEI N EIT + L V+ A+ G+YT + N +GS ++ +++
Sbjct: 28035 WFKDGVEIERRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNVSGSTKAEVTVKVQDT 28094
Query: 1125 KKPPVFDQHLTPVT 1166
V T +T
Sbjct: 28095 PGKVVGPIRFTNIT 28108
Score = 52.8 bits (125), Expect = 1e-06
Identities = 32/100 (32%), Positives = 45/100 (45%)
Frame = +3
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ ++V K+P P D + V EGE L + R + W K G+E+K SDR +
Sbjct: 14418 SENVVAKDPDCKPTIDLETHDIVVIEGEKLNIPVPFRAVPVPTVSWHKDGKEVKASDRLT 14477
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
+ +A LE ADAG Y N GS T+ V
Sbjct: 14478 MKNDHISAHLEVPKSVHADAGVYTITLENKLGSATASINV 14517
Score = 51.2 bits (121), Expect = 3e-06
Identities = 80/375 (21%), Positives = 139/375 (37%), Gaps = 21/375 (5%)
Frame = +3
Query: 336 VSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
+ G V W K ++D I + + +L + +R +G+Y+ T N G+ S
Sbjct: 23009 IKGRPTPEVKWGKVDGDIRDAAIIDVT--SSFTSLVLDNVNRYDSGKYTLTLENSSGTKS 23066
Query: 516 SSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI---RSG 686
+ + + D P PV+ V E +T P+ +K I R
Sbjct: 23067 AFVTVRV--------LDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREA 23118
Query: 687 GNYQISYLENSAHLTILKVDKGDTG---QYTCYAVNE--VGKDSCTAQ-LNIKERLIPPS 848
+ + + H K+D+ G + A NE +G + TA + + E PP
Sbjct: 23119 TRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPARTADPIKVAEVPQPPG 23178
Query: 849 FTKKLSETVEETEGNSFRLEGRV----AGSQPISVAWYKNNVEIHPTANCEITFKNNALL 1016
TV++ NS L GS+ I Y ++ T + +L
Sbjct: 23179 -----KITVDDVTRNSVSLSWTKPEHDGGSKIIQ---YIVEMQAKNTDKWSECARVKSLD 23230
Query: 1017 LQVKKASMGDAGLYTCKVSNDAGSA--------LCTSSIVIKEPKKPPVFDQHLTPVTVS 1172
+ + G+ L+ N+ G + + +VI EP P F + +V
Sbjct: 23231 AVITNLTQGEEYLFRVIAVNEKGRSDPRSLAVPIIAKDLVI-EPDVRPAFSSY----SVQ 23285
Query: 1173 EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVC 1352
G+ L++ + G I W K G +K + R + + + L K+ K D G Y
Sbjct: 23286 VGQDLKIEVPISGRPKPSISWTKDGMPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGI 23345
Query: 1353 KASNVAGSDTSKSKV 1397
SNV G T+ ++
Sbjct: 23346 TVSNVVGQKTAAIEI 23360
Score = 50.4 bits (119), Expect = 5e-06
Identities = 92/418 (22%), Positives = 150/418 (35%), Gaps = 41/418 (9%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVAT---LVFNQVDSN 176
+++ G + + ++ G P W + +L NV T L+
Sbjct: 15157 IQIMAGKTLRIPAEVTGRPVPTKVWTIEEGELDKERV----IIENVGTKSELIIKNALRK 15212
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
D G Y+ A NS G S F V+ + V + G + + V+ +
Sbjct: 15213 DHGRYVITATNSCG----SKFAAVRVE------------VFDVPGPVLDLKPVVTNRKMC 15256
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNI------FQTDRSFAGQYSCTATNPIGSASS 518
++W P DG + T F+ + +T+RS C T I
Sbjct: 15257 LLNW---SDPADDGGSDITGFIIERKDAKMHTWRQPIETERS-----KCDITGLIEGQEY 15308
Query: 519 SARLILTE--GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
R+I G PP P+ VD + G E +T T+ K D +E RS G
Sbjct: 15309 KFRVIAKNKFGCGPPVEIGPILAVDPL-GPPTSPE-RLTYTERTKSTITLDWKEPRSDGG 15366
Query: 693 YQIS--YLENSAH-----------------LTILKVDKGDTGQYTCYAVNEVGKDSCTAQ 815
I +E H + +D+ ++ AVN+VG+ +
Sbjct: 15367 SPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNDVGESEPSLP 15426
Query: 816 LN--IKERLIPPSFTKKLS---ETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIH-PT 977
LN I++ +PP+ +L+ +T++ G + V G + W KN I PT
Sbjct: 15427 LNVVIQDDEVPPTIKLRLAVRGDTIKVKAGEPVNIPADVTGLPMPKIEWSKNEKVIDKPT 15486
Query: 978 ANCEITFKNNALL-----LQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 1136
IT + + L + KA+ D G YT SN GS + + + PP
Sbjct: 15487 DTLNITKEEVSRSEAKTELSIPKAAREDKGTYTITASNRLGSVFRNVHVEVYDRPSPP 15544
Score = 50.4 bits (119), Expect = 5e-06
Identities = 35/150 (23%), Positives = 65/150 (43%), Gaps = 8/150 (5%)
Frame = +3
Query: 165 VDSNDSGEYI--CRAENSVGEVSSS---TFLTVQEQKLPPSFSRQL---RDVQETVGLPV 320
+ N+ +Y+ RA+N G T +TVQ+ ++ P+ + + G P+
Sbjct: 29740 ISLNEGEQYLFRVRAQNEKGVSEPREIVTPVTVQDLRVLPTIDLSTMPQKTIHVPAGRPI 29799
Query: 321 VFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNP 500
++G P + SWF G L++ + V L I +T G+Y+ N
Sbjct: 29800 ELVIPITGRPPPTASWFFAGSKLRESERVTVETHTKVTKLTIRETTIRDTGEYTLELKNV 29859
Query: 501 IGSASSSARLILTEGRNPPFFDIPLAPVDA 590
G+ S + ++I+ + PP I + +DA
Sbjct: 29860 TGTTSETIKVIILDKPGPPTGPIKIDEIDA 29889
>ref|NP_001019891.2| hemicentin 1 [Mus musculus].
Length = 5634
Score = 195 bits (495), Expect = 1e-49
Identities = 159/575 (27%), Positives = 236/575 (41%), Gaps = 2/575 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V V + L+C+ G P ++WYK L +A+ R V + Q+ +D+G Y
Sbjct: 1931 VVVNNPIQLECKATGKPLPVITWYKDSHPLSGSASAAFLKRGQVLEIGSAQI--SDAGIY 1988
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A NS G ++ F ++Q +PPS S V+ V EC G S++W
Sbjct: 1989 KCVAINSAG--ATELFYSLQVH-VPPSISGSSSMVEVVVNNLARLECEARGIPAPSLTWL 2045
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDG P+ N L L + S AG+Y+C A N G L +
Sbjct: 2046 KDGSPVSSFSN-GIQILSGGRILALTSAQMSDAGRYTCVAVNAAGEKQRDIDLRVYA--- 2101
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP V ++G++ + C P + W KD R + IS EN + L
Sbjct: 2102 PPNIMGEEQNVSVLIGQAVELFCQSDAVPPPTLMWLKDGRPLLKRPGLSIS--ENGSVLK 2159
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET--EGNSFRL 905
I GDTG+YTC A N GK +N+ +PPS E V+ T EGN L
Sbjct: 2160 IEDAQAGDTGRYTCEATNVAGKTEKNYNVNV---WVPPSIYGS-DELVQLTAIEGNLITL 2215
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+G P + W K + + + + LQ+ A DAGLYTC SN AG
Sbjct: 2216 LCESSGIPPPDLTWKKKGSLVLADSAGRVHILSGGRRLQISIAEKADAGLYTCVASNVAG 2275
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
A ++ + H +TV G+ + L C V+G + W+K GR +
Sbjct: 2276 VAKKEYNLQVYIRPSITNSGGHRPEITVIRGKSISLECEVQGIPQPTVTWMKDGRPLTKG 2335
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ +L+ K+V +D G YVC A NVAG + ++
Sbjct: 2336 K--GVEILDEGRILQLKNVHVSDTGRYVCVAVNVAGMTDKRYDLSVHAPPSIIGNH---- 2389
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
P+++ VVEK++ + + G P+P++ W K W +N G + I G
Sbjct: 2390 --------GVPENVSVVEKSSVSLTCEASGIPLPSITWLKDGW-PVNLGSSVKILSGG-- 2438
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
L + T D+G Y C+ N GE L V
Sbjct: 2439 RMLRLMQTRPEDAGQYTCIVRNAAGEDRKMFGLSV 2473
Score = 181 bits (459), Expect = 2e-45
Identities = 165/606 (27%), Positives = 256/606 (42%), Gaps = 7/606 (1%)
Frame = +3
Query: 3 PVKVTV--GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSN 176
PV+++V G+ A L C+ P ++W K + P + + + +V +
Sbjct: 1086 PVEISVLAGEEAILPCEAKSLPPPIITWAKDSQLISPFSPRHTFLPSGSMKITETRV--S 1143
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
DSG Y+C A N G V+ S L+V +PP R ++ VG V C GS P
Sbjct: 1144 DSGMYLCVATNIAGNVTQSVKLSVH---VPPKIQHGNRHIKVQVGQRVDILCNAHGSPPP 1200
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
++WFK GRP DG S TL+I Q S AG Y+C ATN GS + L +
Sbjct: 1201 VITWFKSGRPFLDGAQHPGS---PDGTLSIEQAVISDAGVYTCAATNIAGSDEAEVTLHV 1257
Query: 537 TEGRN----PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
E + P F+ P + + + +F C GT + W + RE+ +G +S
Sbjct: 1258 QEPPSVEDLQPPFNTPFQ--ERLANQRIEFPCPAKGTPKPTIKWLHNGREV-TGQEPGVS 1314
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
LE+ A L I V + G+Y C AVNE G + + N+K + P K+ V
Sbjct: 1315 ILEDGALLVIASVTPHNNGEYICVAVNEAG--TTERKYNLKVHVPPVIRDKEHVTNVSVL 1372
Query: 885 EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTC 1064
L V G+ + WYK+++++ ++ +I NN +L++ K S DAG Y+C
Sbjct: 1373 TSQLASLYCEVEGTPSPVITWYKDDIQVTESSTVQIV--NNGKILKLFKVSAEDAGRYSC 1430
Query: 1065 KVSNDAGSALCTSSIVIKEPKKPPVFD-QHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLK 1241
K N AG++ S+ + P P + + V+V + L C G I W K
Sbjct: 1431 KAINIAGTSQKDFSVNVLVP--PSILGASSPSEVSVVLNHNVTLQCPGTGVPFPAIHWFK 1488
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
G+ + D + ++ L ++ ++D G Y C SN AG K+T
Sbjct: 1489 DGKPLFLGDP-NIELSDRGQSLHLRNARRSDKGRYQCTVSNAAGKQAKDIKLTVYVPPSI 1547
Query: 1422 XXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRI 1601
+ L SI +E T G P+P + W K + +
Sbjct: 1548 KGGNITTEISALL------NSIVKLECETR-------GLPVPAITWYKDGQVVTSSSQAL 1594
Query: 1602 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAML 1781
+I KG L I+ +DS Y C A N G E + ++ + IEGDL A
Sbjct: 1595 YI-DKGQ--LLHIQRAQVSDSATYTCHAANVAGTAEKSFHVDI---YVPPTIEGDLTAPS 1648
Query: 1782 KKTPVL 1799
K ++
Sbjct: 1649 NKQVII 1654
Score = 179 bits (454), Expect = 7e-45
Identities = 155/584 (26%), Positives = 240/584 (41%), Gaps = 7/584 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V ASL C++ GTP ++WYK D ++ ++T ++ NN L +V + D+G
Sbjct: 1369 VSVLTSQLASLYCEVEGTPSPVITWYKDDIQVTESSTVQIV--NNGKILKLFKVSAEDAG 1426
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C+A N G + V +PPS + +V + V +C +G +
Sbjct: 1427 RYSCKAINIAGTSQKDFSVNVL---VPPSILGASSPSEVSVVLNHNVTLQCPGTGVPFPA 1483
Query: 360 VSWFKDGRPLKDG-PNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
+ WFKDG+PL G PNI+ S D +L++ RS G+Y CT +N G + +L +
Sbjct: 1484 IHWFKDGKPLFLGDPNIELS--DRGQSLHLRNARRSDKGRYQCTVSNAAGKQAKDIKLTV 1541
Query: 537 TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
+ +I + A++ EC G + W KD + + S Q Y++
Sbjct: 1542 YVPPSIKGGNIT-TEISALLNSIVKLECETRGLPVPAITWYKDGQVVTSSS--QALYIDK 1598
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE--G 890
L I + D+ YTC+A N G + ++I +PP+ L+ + G
Sbjct: 1599 GQLLHIQRAQVSDSATYTCHAANVAGTAEKSFHVDI---YVPPTIEGDLTAPSNKQVIIG 1655
Query: 891 NSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
S LE + AG+ P + W K+ V + + N I + L++ A D G Y C
Sbjct: 1656 QSLILECKAAGNPPPILTWLKDGVPVKASDNIHI--EAGGKKLEILSALEVDRGQYICVA 1713
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFD--QHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKA 1244
++ AG + + P P + + + V L+L C V GS P I WLK
Sbjct: 1714 TSVAGEREIKYEVDVLVP---PAVEGGEETSYFIVLANNLLELDCQVSGSPPPTIMWLKG 1770
Query: 1245 GREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXX 1424
G+ I +R F L +D G Y C A+N+AG + +VT
Sbjct: 1771 GQLI--DERDGFKILLNGRKLVIAQAQVSDTGLYQCVATNIAGDHRKEFEVTVHVPPTIK 1828
Query: 1425 XXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIF 1604
S+ VV T G P P++ W K G +
Sbjct: 1829 S--------------SDLPEKTVVRYKPVTLQCIANGIPNPSITWLKDDQPVNTAHGNLK 1874
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
I G L+I D+G Y CVA N GE + L V+E
Sbjct: 1875 IQSSG--RVLQIAKALLEDAGRYTCVATNAAGEAHQHTQLHVHE 1916
Score = 178 bits (451), Expect = 2e-44
Identities = 139/581 (23%), Positives = 250/581 (43%), Gaps = 5/581 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G S SL+C+ P ++W K ++ P +T + TL + + +D+G
Sbjct: 3068 VNVREGTSVSLECESNAVPPPVITWSKNG-RMIPDST-NVEILTGGQTLHIRRAEVSDTG 3125
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDV-QETVGLPVVFECAVSGSEPISV 362
+Y+CRA N G + L V +PP+ +V ET+ PV C +G P ++
Sbjct: 3126 QYVCRAINVAGRDDKNFHLNVY---VPPTIEGPETEVIVETISNPVTLTCDATGIPPPTI 3182
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+ +P+++ ++ L + L I + RS +G Y+C A+N G A + L +
Sbjct: 3183 TWLKNHKPIENSDPLEVHILSGGSKLQIARPQRSNSGNYTCVASNMEGKAQKNFILFIQV 3242
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ ++P + V ++GE+ + C+ G + W +D + I +G ++ + +
Sbjct: 3243 PPSVAGAEVP-SEVSVLLGENVELVCNADGIPTPHLQWLRDGKPIVNGETERVRVTTDGS 3301
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF--TKKLSETVEETEGNS 896
L I + D G+YTC A N G++ LN+ +PP K+ +E + S
Sbjct: 3302 TLNIYRALTSDMGKYTCVATNPAGEEDRIFNLNV---YVPPKIRGNKEEAEKLMALVDTS 3358
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
+E + G+ P + W KN + + + I + ++++ +A + D +YTC SN
Sbjct: 3359 INIECKATGTPPPQINWLKNGLPL--PISSHIRLLSAGQVVRIVRAQVSDIAVYTCVASN 3416
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHL--TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
AG S + PP D + +T+ +G ++C G+ + WL+ G+
Sbjct: 3417 RAG---VDSKHYSLQVFVPPNMDNAMGTEEITIVKGSSTSMTCFTDGTPAPSMSWLRDGQ 3473
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
+ P + S VL+ D G Y C A+N AG + SK V
Sbjct: 3474 PLAPDAHLTVSTQG--MVLQLIKAETEDTGKYTCVATNEAG-EVSKHFV--------LKV 3522
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
++G P + V+ G P P + W K R Q ++
Sbjct: 3523 LEPPHINGS----EGPGEVSVIVNNPLELSCIASGIPAPKISWMK-DGRPFLQTEQVQTL 3577
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
+ G A L + D+G Y C+A + G+ + ++V+
Sbjct: 3578 EGG--AILRVSSAQVEDTGRYTCLASSPAGDDDKEYLVRVH 3616
Score = 177 bits (450), Expect = 2e-44
Identities = 153/580 (26%), Positives = 230/580 (39%), Gaps = 5/580 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V V S ++C +G P W K L +K F+++ +L D+G
Sbjct: 2881 VTVLVNKSTQMECSSSGNPAPRNYWQKDGQILLEDEHHK--FQSDGRSLQILNAQITDTG 2938
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPS-FSRQLRDVQETVGLPVVFECAVSGSEPISV 362
Y+C AEN+ G L V +PPS + V + C VSG P +
Sbjct: 2939 RYVCVAENTAGSAKKYFNLNVH---VPPSVIGPNHEHLSVVVNHFISLNCEVSGFPPPDL 2995
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SW K+ P+K N+ T + TL I + S G Y+C A N G S ++ LT
Sbjct: 2996 SWLKNEEPIKPNTNVLT--VPGGRTLQIIRAKISDGGDYTCIAINQAG--ESKKKVSLTV 3051
Query: 543 GRNPPFFD---IPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
P D L+ V+ G S EC P + W+K+ R I N +I L
Sbjct: 3052 HVPPSIKDHGSQSLSIVNVREGTSVSLECESNAVPPPVITWSKNGRMIPDSTNVEI--LT 3109
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN 893
L I + + DTGQY C A+N G+D LN+ +PP+ +E + ET N
Sbjct: 3110 GGQTLHIRRAEVSDTGQYVCRAINVAGRDDKNFHLNV---YVPPTIEGPETEVIVETISN 3166
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
L G P ++ W KN+ I + E+ + LQ+ + ++G YTC S
Sbjct: 3167 PVTLTCDATGIPPPTITWLKNHKPIENSDPLEVHILSGGSKLQIARPQRSNSGNYTCVAS 3226
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
N G A + I+ P P V + + V+V GE ++L C+ G +QWL+ G+
Sbjct: 3227 NMEGKAQKNFILFIQVP--PSVAGAEVPSEVSVLLGENVELVCNADGIPTPHLQWLRDGK 3284
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
I + + L +D G Y C A+N AG + +
Sbjct: 3285 PIVNGETERVRVTTDGSTLNIYRALTSDMGKYTCVATNPAGEEDRIFNLNVYVPPKIRGN 3344
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
E + + + T+ K G P P + W K L I +
Sbjct: 3345 K------------EEAEKLMALVDTSINIECKATGTPPPQINWLK-NGLPLPISSHIRLL 3391
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
G + I +D +Y CVA N+ G + +LQV
Sbjct: 3392 SAGQVVR--IVRAQVSDIAVYTCVASNRAGVDSKHYSLQV 3429
Score = 177 bits (449), Expect = 3e-44
Identities = 152/570 (26%), Positives = 229/570 (40%), Gaps = 3/570 (0%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENS 212
+LQC G P ++W K D + TA + +++ L + D+G Y C A N+
Sbjct: 1844 TLQCIANGIPNPSITWLKDDQPVN-TAHGNLKIQSSGRVLQIAKALLEDAGRYTCVATNA 1902
Query: 213 VGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRP 386
GE T L V E PPS + ++R+ V P+ EC +G ++W+KD P
Sbjct: 1903 AGEAHQHTQLHVHE---PPSLDDAGKMRNETVVVNNPIQLECKATGKPLPVITWYKDSHP 1959
Query: 387 LKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFD 566
L + +FL L I S AG Y C A N SA ++ + PP
Sbjct: 1960 LSGSAS--AAFLKRGQVLEIGSAQISDAGIYKCVAIN---SAGATELFYSLQVHVPPSIS 2014
Query: 567 IPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVD 746
+ V+ VV A EC G + W KD + S N I L L +
Sbjct: 2015 GSSSMVEVVVNNLARLECEARGIPAPSLTWLKDGSPVSSFSN-GIQILSGGRILALTSAQ 2073
Query: 747 KGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGS 926
D G+YTC AVN G+ Q +I R+ P + V G + L +
Sbjct: 2074 MSDAGRYTCVAVNAAGEK----QRDIDLRVYAPPNIMGEEQNVSVLIGQAVELFCQSDAV 2129
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS 1106
P ++ W K+ + I+ N +L+++ A GD G YTC+ +N AG +
Sbjct: 2130 PPPTLMWLKDGRPLLKRPGLSIS--ENGSVLKIEDAQAGDTGRYTCEATNVAGKTEKNYN 2187
Query: 1107 IVIKEPKKPPVF-DQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFS 1283
+ + P P ++ L +T EG + L C G P + W K G +
Sbjct: 2188 VNVWVP--PSIYGSDELVQLTAIEGNLITLLCESSGIPPPDLTWKKKGSLVLADSAGRVH 2245
Query: 1284 FANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLF 1463
+G L+ KADAG Y C ASNVAG + +
Sbjct: 2246 ILSGGRRLQISIAEKADAGLYTCVASNVAGVAKKEYNLQVYIRPSITNSG---------- 2295
Query: 1464 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIR 1643
I V+ + + +V G P P V W K R L +G + I +G L+++
Sbjct: 2296 --GHRPEITVIRGKSISLECEVQGIPQPTVTWMK-DGRPLTKGKGVEILDEG--RILQLK 2350
Query: 1644 DTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
+ +D+G Y CVA N G + +L V+
Sbjct: 2351 NVHVSDTGRYVCVAVNVAGMTDKRYDLSVH 2380
Score = 170 bits (430), Expect = 4e-42
Identities = 148/584 (25%), Positives = 228/584 (39%), Gaps = 9/584 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYK--MHFRNNVATLVFNQVDSND 179
V+V V + A L+C+ G P ++W K + P +++ + + L +D
Sbjct: 2020 VEVVVNNLARLECEARGIPAPSLTWLKDGS---PVSSFSNGIQILSGGRILALTSAQMSD 2076
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
+G Y C A N+ GE L V PP+ + ++V +G V C P +
Sbjct: 2077 AGRYTCVAVNAAGEKQRDIDLRVYA---PPNIMGEEQNVSVLIGQAVELFCQSDAVPPPT 2133
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
+ W KDGRPL P + S +N + L I G+Y+C ATN G + + +
Sbjct: 2134 LMWLKDGRPLLKRPGLSIS--ENGSVLKIEDAQAGDTGRYTCEATNVAGKTEKNYNVNVW 2191
Query: 540 EGRNPP--FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
PP + L + A+ G C +G P + W K + + ++ L
Sbjct: 2192 V---PPSIYGSDELVQLTAIEGNLITLLCESSGIPPPDLTWKKKGSLVLADSAGRVHILS 2248
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET--E 887
L I +K D G YTC A N G L + I PS T E T
Sbjct: 2249 GGRRLQISIAEKADAGLYTCVASNVAGVAKKEYNLQV---YIRPSITNSGGHRPEITVIR 2305
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
G S LE V G +V W K+ + EI + +LQ+K + D G Y C
Sbjct: 2306 GKSISLECEVQGIPQPTVTWMKDGRPLTKGKGVEIL--DEGRILQLKNVHVSDTGRYVCV 2363
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTP--VTVSEGEFLQLSCHVRGSEPIRIQWLK 1241
N AG + + P P + H P V+V E + L+C G I WLK
Sbjct: 2364 AVNVAGMTDKRYDLSVHAP--PSIIGNHGVPENVSVVEKSSVSLTCEASGIPLPSITWLK 2421
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
G + S +G +L DAG Y C N AG D ++
Sbjct: 2422 DGWPVNLGS--SVKILSGGRMLRLMQTRPEDAGQYTCIVRNAAGEDRKMFGLSVL----- 2474
Query: 1422 XXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQLNQGGR 1598
V + + + +++ EK + T +V G+P+P + W K G+ Q ++
Sbjct: 2475 --------VPPHIVGENTLEDVKIKEKQSVTLTCEVRGNPVPQITWHKDGQLLQEDEAH- 2525
Query: 1599 IFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
H L+I + + +G Y C+A N G+ + L V
Sbjct: 2526 ---HMMSGGRFLQITNAQVSHTGRYTCLASNIAGDKSKSFRLNV 2566
Score = 162 bits (409), Expect = 1e-39
Identities = 152/572 (26%), Positives = 225/572 (39%), Gaps = 3/572 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VTV +L C+ G P+ V+W K L + + +LV +D+
Sbjct: 3812 VTVTVNVQTTLACEATGIPKPSVTWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 3871
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C + GE + LTVQ +PP+ + + D T P V C+ SG S+
Sbjct: 3872 SYECTVTSDAGEDKRAVDLTVQ---VPPTIADEPMDFLVTRQAPAVMTCSASGVPVPSIH 3928
Query: 366 WFKDG---RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
W K+G P DG I +S + I T + AG+Y+C A N GSA L +
Sbjct: 3929 WTKNGLRLLPRGDGYRILSS-----GAIEIPTTQLNHAGRYTCVARNAAGSAHRHVTLRV 3983
Query: 537 TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
E PP + +D ++ C TG + W K+ + + G ++ L
Sbjct: 3984 QE---PPVIQPQPSELDVILNNPILLPCEATGIPTPFITWQKEGINVITSGK-SLAILP- 4038
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
S L I + +GD G Y C A N G +LN++ +PP + E V T
Sbjct: 4039 SGSLQISRAVRGDAGTYMCVAQNPAGTALGKVKLNVQ---VPPVISSHQKEYV-VTMDKP 4094
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
L GS P + W+K+ + + I N+ LQ+ A DAG YTC +N
Sbjct: 4095 VSLLCETEGSPPPDITWHKDGHALTESIRQRIL---NSGALQIAFAQPDDAGQYTCMAAN 4151
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
AGS+ +S++ + P + + H TV+E L C G I W K G I
Sbjct: 4152 MAGSSSVSSTLTVHVPPRIQSTEVHF---TVNENSQAVLPCVADGIPTPAIHWEKDGVLI 4208
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
+ G +LE +V D+G Y C A+N AG DT
Sbjct: 4209 ANLLGKYTAQPYGELILE--NVVLEDSGTYTCVANNAAGEDT---------------RIV 4251
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
V F P + + + K G P+P + WT N
Sbjct: 4252 TLAVHTLPTFTELPGDLSLNKGEQLRLSCKAVGIPLPKLTWTFN-----NNIIPAHFDSI 4306
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIES 1712
++L I +K DSG Y C A N G +++
Sbjct: 4307 NGHSELVIEKVSKEDSGTYVCTAENSVGFVKA 4338
Score = 158 bits (400), Expect = 1e-38
Identities = 151/599 (25%), Positives = 233/599 (38%), Gaps = 23/599 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK+ S +L C++ G P ++W+K L+ + H + L + +G
Sbjct: 2488 VKIKEKQSVTLTCEVRGNPVPQITWHKDGQLLQEDEAH--HMMSGGRFLQITNAQVSHTG 2545
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQ--LRDVQETVGLPVVFECAVSGSEPIS 359
Y C A N G+ S S L V DV + P C P +
Sbjct: 2546 RYTCLASNIAGDKSKSFRLNVFVSPTIAGVDSDGSPEDVIVILNSPTSLVCEAYSYPPAT 2605
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL--- 530
++WFKDG PL+ NI+ L TL I AG+YSC ATN G +
Sbjct: 2606 ITWFKDGTPLESNRNIR--ILPGGRTLQILNAQEDNAGRYSCVATNEAGEKIKHYEVKVY 2663
Query: 531 ---ILTEGRNPPFFDIPLAP--VDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNY 695
I+ +G L+P V V S EC + W KD + ++S +
Sbjct: 2664 IPPIIKKG---DLLGPGLSPKEVKIRVNSSLTLECEAYAIPSASLRWYKDGQPLKSDDHV 2720
Query: 696 QISYLENSAH-LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK----- 857
I+ S H L I + DTG+YTC A N G+D +NI+ +PPSF K
Sbjct: 2721 TIAA---SGHTLQIKEAQISDTGRYTCVASNLAGEDELDFDVNIQ---VPPSFQKLWEIG 2774
Query: 858 ------KLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLL 1019
+ E + N L + P ++ WYK+ + T++ + +L
Sbjct: 2775 NMLDTGRSGEAKDVIINNPLSLHCETNAAPPPTLTWYKDGRPL--TSSDRVLILPGGRVL 2832
Query: 1020 QVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP-VTVSEGEFLQLS 1196
Q+ +A + DAG YTC N+AG + + P + L VTV + Q+
Sbjct: 2833 QIPRAKVEDAGRYTCVAVNEAGEDSLRYDVHVLLPPVIKGANSDLPEEVTVLVNKSTQME 2892
Query: 1197 CHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGS 1376
C G+ R W K G+ + + F ++G + L+ + D G YVC A N AGS
Sbjct: 2893 CSSSGNPAPRNYWQKDGQILLEDEHHKFQ-SDGRS-LQILNAQITDTGRYVCVAENTAGS 2950
Query: 1377 DTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVK 1556
+ + + VV + +V G P P++
Sbjct: 2951 AKKYFNLNVHVPPSVIGPNH--------------EHLSVVVNHFISLNCEVSGFPPPDLS 2996
Query: 1557 WTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
W K + + + G L+I +D G Y C+A N+ GE + V+L V+
Sbjct: 2997 WLKNE-EPIKPNTNVLTVPGG--RTLQIIRAKISDGGDYTCIAINQAGESKKKVSLTVH 3052
Score = 158 bits (399), Expect = 2e-38
Identities = 149/596 (25%), Positives = 236/596 (39%), Gaps = 20/596 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + + +LQC G P + W+K D K + + +L +D G
Sbjct: 1462 VSVVLNHNVTLQCPGTGVPFPAIHWFK-DGKPLFLGDPNIELSDRGQSLHLRNARRSDKG 1520
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFS--RQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C N+ G+ + LTV +PPS ++ + V EC G +
Sbjct: 1521 RYQCTVSNAAGKQAKDIKLTVY---VPPSIKGGNITTEISALLNSIVKLECETRGLPVPA 1577
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W+KDG+ + Q ++D L+I + S + Y+C A N G+A S + +
Sbjct: 1578 ITWYKDGQVVTSSS--QALYIDKGQLLHIQRAQVSDSATYTCHAANVAGTAEKSFHVDIY 1635
Query: 540 EGRNPPFFDIPL-APVD--AVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
PP + L AP + ++G+S EC G P + W KD +++ N I
Sbjct: 1636 V---PPTIEGDLTAPSNKQVIIGQSLILECKAAGNPPPILTWLKDGVPVKASDNIHIE-- 1690
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE- 887
L IL + D GQY C A + G+ ++++ L+PP+ E EET
Sbjct: 1691 AGGKKLEILSALEVDRGQYICVATSVAGEREIKYEVDV---LVPPAV-----EGGEETSY 1742
Query: 888 -----GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAG 1052
N L+ +V+GS P ++ W K I +I L+ + +A + D G
Sbjct: 1743 FIVLANNLLELDCQVSGSPPPTIMWLKGGQLIDERDGFKILLNGRKLV--IAQAQVSDTG 1800
Query: 1053 LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQ 1232
LY C +N AG + + P P + L TV + + L C G I
Sbjct: 1801 LYQCVATNIAGDHRKEFEVTVHVP--PTIKSSDLPEKTVVRYKPVTLQCIANGIPNPSIT 1858
Query: 1233 WLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXX 1412
WLK + + + + + VL+ DAG Y C A+N AG +++
Sbjct: 1859 WLKDDQPVNTAHG-NLKIQSSGRVLQIAKALLEDAGRYTCVATNAAGEAHQHTQL----- 1912
Query: 1413 XXXXXXXXXXXVDGKLFFVSEPQSI---------RVVEKTTATFIAKVGGDPIPNVKWTK 1565
V EP S+ VV K G P+P + W K
Sbjct: 1913 -----------------HVHEPPSLDDAGKMRNETVVVNNPIQLECKATGKPLPVITWYK 1955
Query: 1566 GKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
F+ ++G LEI +D+G+Y+CVA N G E +LQV+
Sbjct: 1956 DSHPLSGSASAAFL-KRGQV--LEIGSAQISDAGIYKCVAINSAGATELFYSLQVH 2008
Score = 158 bits (399), Expect = 2e-38
Identities = 140/583 (24%), Positives = 230/583 (39%), Gaps = 6/583 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ V V SL C+++G P +SW K + ++P ++ ++ +D G
Sbjct: 2973 LSVVVNHFISLNCEVSGFPPPDLSWLKNEEPIKPNTNV2998
Score = 120 bits (300), Expect = 6e-27
Identities = 108/390 (27%), Positives = 163/390 (41%), Gaps = 11/390 (2%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G++ LQC GTP + W + + L AT RN + L F + DSG Y
Sbjct: 3310 VQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATA----RNEL--LHFERAAPEDSGRY 3363
Query: 192 ICRAENSVGEVSSSTFLTVQEQ--KLP----PSFSRQLRDVQ-----ETVGLPVVFECAV 338
CR N VG + L VQ LP P+ S V +++G V F CAV
Sbjct: 3364 RCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAV 3423
Query: 339 SGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASS 518
+ WFK+G L G ++Q L I D+S G Y C A P G A +
Sbjct: 3424 PSDRGTQLRWFKEGGQLPPGHSVQD------GVLRIQNLDQSCQGTYICQAHGPWGKAQA 3477
Query: 519 SARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQ 698
SA+L++ + +I + VVG + +FEC G +V W+K GG+ +
Sbjct: 3478 SAQLVI-QALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSK------VGGHLR 3530
Query: 699 ISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE 878
+++ + I V+ D GQY C A N G T Q ++ L+ + + V
Sbjct: 3531 PGIVQSGGVVRIAHVELADAGQYRCTATNAAG----TTQSHVL-LLVQALPQISMPQEVR 3585
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
G++ +G ++W K + + P + E NN L+L + DAG Y
Sbjct: 3586 VPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRLE----NNMLMLPSVRPQ--DAGTY 3639
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFDQ 1148
C +N G + + + E + P F Q
Sbjct: 3640 VCTATNRQGKVKAFAHLQVPE-RVVPYFTQ 3668
Score = 66.2 bits (160), Expect = 1e-10
Identities = 61/208 (29%), Positives = 83/208 (39%), Gaps = 2/208 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V VG + +C G P+ V+W K LRP + + V+ D+G+Y
Sbjct: 3500 VVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIV------QSGGVVRIAHVELADAGQY 3553
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A N+ G S L VQ P S ++V+ G VF C SG +SW
Sbjct: 3554 RCTATNAAGTTQSHVLLLVQAL---PQISMP-QEVRVPAGSAAVFPCIASGYPTPDISWS 3609
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K DG S L+N L + AG Y CTATN G + A L + E
Sbjct: 3610 K-----LDGSLPPDSRLEN-NMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPERVV 3663
Query: 552 PPFFDIPLA--PVDAVVGESADFECHVT 629
P F P + P+ + FE +T
Sbjct: 3664 PYFTQTPYSFLPLPTIKDAYRKFEIKIT 3691
>ref|NP_001139317.1| roundabout homolog 1 isoform d [Homo sapiens].
Length = 1551
Score = 156 bits (394), Expect = 8e-38
Identities = 136/473 (28%), Positives = 194/473 (41%), Gaps = 16/473 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKG----DTKLRPTATYKMHFRNN---VATLVFNQVD 170
V+ G+ A+L C+ G P + WYKG +T +++M + +V +
Sbjct: 40 VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 99
Query: 171 SNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
D G Y+C A N +GE S +++ L F + DV VG P V EC
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHN-ASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGH 158
Query: 351 P-ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSAR 527
P ++SW KDG PL D T L I T +S AG+Y C TN +G S
Sbjct: 159 PEPTISWKKDGSPLDDKDERITI---RGGKLMITYTRKSDAGKYVCVGTNMVGERESEV- 214
Query: 528 LILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISY 707
LT P F P + + V +SA+F+C G V W KD+ E+ Y+I
Sbjct: 215 AELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRYEI-- 270
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
+ L I KV GD G YTC A N VGK +A L ++ PP F K + V
Sbjct: 271 -RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVAL- 328
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVE-----LTVPGGRTLQIIRAKI--SDGG 3030
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF----SRQLRDVQETVGLPVVFECAVSGSEP 353
+Y C A N GE LTV +PPS S+ L V G V EC + P
Sbjct: 3031 DYTCIAINQAGESKKKVSLTVH---VPPSIKDHGSQSLSIVNVREGTSVSLECESNAVPP 3087
Query: 354 ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
++W K+GR + D N++ L TL+I + + S GQY C A N G + L
Sbjct: 3088 PVITWSKNGRMIPDSTNVE--ILTGGQTLHIRRAEVSDTGQYVCRAINVAGRDDKNFHLN 3145
Query: 534 LTEGRNPPFFDIPLAPVDA-VVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
+ PP + P V + C TG P + W K+++ I + ++ L
Sbjct: 3146 VYV---PPTIEGPETEVIVETISNPVTLTCDATGIPPPTITWLKNHKPIENSDPLEVHIL 3202
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKLSETVEETE 887
+ L I + + ++G YTC A N GK L I+ +PPS ++ V
Sbjct: 3203 SGGSKLQIARPQRSNSGNYTCVASNMEGKAQKNFILFIQ---VPPSVAGAEVPSEVSVLL 3259
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
G + L G + W ++ I + + L + +A D G YTC
Sbjct: 3260 GENVELVCNADGIPTPHLQWLRDGKPIVNGETERVRVTTDGSTLNIYRALTSDMGKYTCV 3319
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
+N AG ++ + P K + + + + C G+ P +I WLK G
Sbjct: 3320 ATNPAGEEDRIFNLNVYVPPKIRGNKEEAEKLMALVDTSINIECKATGTPPPQINWLKNG 3379
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
+ S A V+ +D Y C ASN AG D+ +
Sbjct: 3380 LPLPISSHIRLLSAG--QVVRIVRAQVSDIAVYTCVASNRAGVDSKHYSLQVF------- 3430
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
V + + I +V+ ++ + G P P++ W + + L + +
Sbjct: 3431 ------VPPNMDNAMGTEEITIVKGSSTSMTCFTDGTPAPSMSWLRDG-QPLAPDAHLTV 3483
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+G +L +T D+G Y CVA N+ GE+ + L+V E
Sbjct: 3484 STQGMVLQLIKAETE--DTGKYTCVATNEAGEVSKHFVLKVLE 3524
Score = 157 bits (398), Expect = 2e-38
Identities = 156/600 (26%), Positives = 230/600 (38%), Gaps = 24/600 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V S SL C+ +G P ++W K + ++ K+ + L+ Q D+G
Sbjct: 2395 VSVVEKSSVSLTCEASGIPLPSITWLKDGWPVNLGSSVKILSGGRMLRLM--QTRPEDAG 2452
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPIS 359
+Y C N+ GE L+V +PP L DV+ V C V G+
Sbjct: 2453 QYTCIVRNAAGEDRKMFGLSVL---VPPHIVGENTLEDVKIKEKQSVTLTCEVRGNPVPQ 2509
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W KDG+ L++ + L I S G+Y+C A+N G S S RL +
Sbjct: 2510 ITWHKDGQLLQEDE--AHHMMSGGRFLQITNAQVSHTGRYTCLASNIAGDKSKSFRLNVF 2567
Query: 540 EGRNPPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
D +P D +V C P + W KD + S N +I L
Sbjct: 2568 VSPTIAGVDSDGSPEDVIVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI--LP 2625
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI-------KERLIPPSFTKKLSET 872
L IL + + G+Y+C A NE G+ ++ + K L+ P + K
Sbjct: 2626 GGRTLQILNAQEDNAGRYSCVATNEAGEKIKHYEVKVYIPPIIKKGDLLGPGLSPK---E 2682
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAG 1052
V+ +S LE S+ WYK+ + ++ +T + LQ+K+A + D G
Sbjct: 2683 VKIRVNSSLTLECEAYAIPSASLRWYKDGQPLK--SDDHVTIAASGHTLQIKEAQISDTG 2740
Query: 1053 LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPV-----TVSEGEF--------LQL 1193
YTC SN AG + I+ P P F Q L + T GE L L
Sbjct: 2741 RYTCVASNLAGEDELDFDVNIQVP---PSF-QKLWEIGNMLDTGRSGEAKDVIINNPLSL 2796
Query: 1194 SCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAG 1373
C + P + W K GR + SDR G VL+ DAG Y C A N AG
Sbjct: 2797 HCETNAAPPPTLTWYKDGRPLTSSDRVLI--LPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2854
Query: 1374 SDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNV 1553
IHPTANCEITFKNNALLLQVKKASMGDAG 1052
G + + G+ ++ W + + P + + L + D G
Sbjct: 329 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVG 388
Query: 1053 LYTCKVSNDAGSALCTSSIVIKE---PKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
Y C+ N AGS + + + + + + PPV Q TV+ LSC GS
Sbjct: 389 YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVP 448
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
I W K G + D NG VL+ + D G Y C AS +G T
Sbjct: 449 TILWRKDGVLVSTQDSRIKQLENG--VLQIRYAKLGDTGRYTCIASTPSGEAT 499
Score = 134 bits (336), Expect = 4e-31
Identities = 132/522 (25%), Positives = 209/522 (40%), Gaps = 25/522 (4%)
Frame = +3
Query: 246 VQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPL---KDGPNIQTS 416
++++ PP D+ + G P C G ++ W+K G + KD P
Sbjct: 22 LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81
Query: 417 FLDNVATLNIF----QTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPV 584
L + + + + R G Y C A N +G A S + F P + V
Sbjct: 82 LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNP-SDV 140
Query: 585 DAVVGESADFECHVTGTQPIK-VAWAKDNREIRS--------GGNYQISYLENSAHLTIL 737
VGE A EC P ++W KD + GG I+Y
Sbjct: 141 MVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTR-------- 192
Query: 738 KVDKGDTGQYTCYAVNEVG-KDSCTAQLNIKERLIPPSFTKKLSE-TVEETEGNSFRLEG 911
K D G+Y C N VG ++S A+L + ER PSF K+ S V + F+ E
Sbjct: 193 ---KSDAGKYVCVGTNMVGERESEVAELTVLER---PSFVKRPSNLAVTVDDSAEFKCEA 246
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
R G +V W K++ E+ P + EI + L+++K + GD G YTC N G A
Sbjct: 247 R--GDPVPTVRWRKDDGEL-PKSRYEIRDDHT---LKIRKVTAGDMGSYTCVAENMVGKA 300
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE-----I 1256
++++ ++ +PP F V+ G + C G+ I W + G +
Sbjct: 301 EASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSY 360
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS--KVTXXXXXXXXXX 1430
+P S + T L +V ++D G Y+C+ NVAGS +K+ +VT
Sbjct: 361 QPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPV 420
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
V+ Q++ V + +A G P+P + W K Q RI
Sbjct: 421 IRQGPVN---------QTVAVDGTFVLSCVAT--GSPVPTILWRKDGVLVSTQDSRI--- 466
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
++ + L+IR D+G Y C+A GE + ++V E
Sbjct: 467 KQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQE 508
Score = 119 bits (299), Expect = 8e-27
Identities = 93/287 (32%), Positives = 132/287 (45%), Gaps = 10/287 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VTV DSA +C+ G P V W K D +L P + Y++ + TL +V + D G Y
Sbjct: 234 VTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDDH---TLKIRKVTAGDMGSY 289
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C AEN VG+ +S LTVQ PP F + RD +G V F+C +G+ ++ W
Sbjct: 290 TCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR 349
Query: 372 KDGRP----LKDGPNIQTSF-LDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
++G P + F + L I RS G Y C N GS + A L +
Sbjct: 350 REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV 409
Query: 537 TE---GRNPPFFDIPLAPVDAVVGESADF--ECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
T+ R PP I PV+ V F C TG+ + W KD + S + +I
Sbjct: 410 TDVIADRPPPV--IRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDG-VLVSTQDSRI 466
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP 842
LEN L I GDTG+YTC A G+ + +A + ++E +P
Sbjct: 467 KQLENGV-LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVP 512
>ref|NP_002932.1| ro D+ + V P+ + V+ + G+P P
Sbjct: 2855 EDSLRYDVHVLLPPVIKGANSDL-----------PEEVTVLVNKSTQMECSSSGNPAPRN 2903
Query: 1554 KWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
W K L F + D L+I + TD+G Y CVA N G + NL V+
Sbjct: 2904 YWQKDGQILLEDEHHKF---QSDGRSLQILNAQITDTGRYVCVAENTAGSAKKYFNLNVH 2960
Score = 153 bits (387), Expect = 4e-37
Identities = 152/587 (25%), Positives = 224/587 (38%), Gaps = 6/587 (1%)
Frame = +3
Query: 27 SASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDS---NDSGEYIC 197
S +L+C+ G P ++W K L + H R ++ F ++S D+G Y+C
Sbjct: 3728 SIALECRAEGVPAPRITWRKDGVVLAES-----HARYSILENGFLHIESAHVTDTGRYLC 3782
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKD 377
A N G L V +PPS + +V TV + C +G SV+W K+
Sbjct: 3783 MATNVAGTDRRRIDLQVH---VPPSIAMGPTNVTVTVNVQTTLACEATGIPKPSVTWRKN 3839
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
G L N + L + +L I Y CT T+ G + L + + PP
Sbjct: 3840 GHLLNVDQNQNSYRLLSSGSLVIISPSVDDTASYECTVTSDAGEDKRAVDLTV---QVPP 3896
Query: 558 FFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDN-REIRSGGNYQISYLENSAHL 728
I P+D +V A C +G + W K+ R + G Y+I +S +
Sbjct: 3897 --TIADEPMDFLVTRQAPAVMTCSASGVPVPSIHWTKNGLRLLPRGDGYRIL---SSGAI 3951
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
I G+YTC A N G L ++E PP + SE ++ N L
Sbjct: 3952 EIPTTQLNHAGRYTCVARNAAGSAHRHVTLRVQE---PPVIQPQPSE-LDVILNNPILLP 4007
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
G + W K + + + + +L Q+ +A GDAG Y C N AG+
Sbjct: 4008 CEATGIPTPFITWQKEGINVITSGKSLAILPSGSL--QISRAVRGDAGTYMCVAQNPAGT 4065
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
AL + ++ P PV H V+ + + L C GS P I W K G + S
Sbjct: 4066 ALGKVKLNVQVP---PVISSHQKEYVVTMDKPVSLLCETEGSPPPDITWHKDGHALTESI 4122
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
R + L+ DAG Y C A+N+AGS + S +T
Sbjct: 4123 RQRIL---NSGALQIAFAQPDDAGQYTCMAANMAGSSSVSSTLTVHVPPRIQ-------- 4171
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
S V E + A G P P + W K N G+ G+
Sbjct: 4172 -------STEVHFTVNENSQAVLPCVADGIPTPAIHWEKDGVLIANLLGKYTAQPYGE-- 4222
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDL 1769
L + + DSG Y CVA N GE V L V+ ++ GDL
Sbjct: 4223 -LILENVVLEDSGTYTCVANNAAGEDTRIVTLAVHTLPTFTELPGDL 4268
Score = 151 bits (382), Expect = 2e-36
Identities = 151/600 (25%), Positives = 234/600 (39%), Gaps = 25/600 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + SL C+ P ++W+K T L ++ TL +++G
Sbjct: 2584 VIVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI--LPGGRTLQILNAQEDNAG 2641
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSR--------QLRDVQETVGLPVVFECAVS 341
Y C A N GE + V +PP + ++V+ V + EC
Sbjct: 2642 RYSCVATNEAGEKIKHYEVKVY---IPPIIKKGDLLGPGLSPKEVKIRVNSSLTLECEAY 2698
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
S+ W+KDG+PLK ++ + + TL I + S G+Y+C A+N G
Sbjct: 2699 AIPSASLRWYKDGQPLKSDDHVTIAASGH--TLQIKEAQISDTGRYTCVASNLAGEDELD 2756
Query: 522 ARLILTEGRNPPFFDIPLAPV-------------DAVVGESADFECHVTGTQPIKVAWAK 662
+ + + PP F L + D ++ C P + W K
Sbjct: 2757 FDVNI---QVPPSFQ-KLWEIGNMLDTGRSGEAKDVIINNPLSLHCETNAAPPPTLTWYK 2812
Query: 663 DNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP 842
D R + S I L L I + D G+YTC AVNE G+DS +++ L+P
Sbjct: 2813 DGRPLTSSDRVLI--LPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLRYDVHV---LLP 2867
Query: 843 PSFTKKLSETVEETE---GNSFRLEGRVAGSQPISVAWYKNNVEIHPTundabout homolog 1 isoform a precursor [Homo sapiens].
Length = 1651
Score = 156 bits (394), Expect = 8e-38
Identities = 137/473 (28%), Positives = 195/473 (41%), Gaps = 16/473 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKG----DTKLRPTATYKMHFRNN---VATLVFNQVD 170
V+ G+ A+L C+ G P + WYKG +T +++M + +V +
Sbjct: 79 VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 138
Query: 171 SNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
D G Y+C A N +GE S +++ L F + DV VG P V EC
Sbjct: 139 RPDEGVYVCVARNYLGEAVSHN-ASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGH 197
Query: 351 P-ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSAR 527
P ++SW KDG PL D T L I T +S AG+Y C TN +G S
Sbjct: 198 PEPTISWKKDGSPLDDKDERITI---RGGKLMITYTRKSDAGKYVCVGTNMVGERESEV- 253
Query: 528 LILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISY 707
LT P F P + + V +SA+F+C G V W KD+ E+ Y+I
Sbjct: 254 AELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRYEI-- 309
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
+ L I KV GD G YTC A N VGK +A L ++E PP F K + V
Sbjct: 310 -RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQE---PPHFVVKPRDQVVAL- 364
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVE-----IHPTANCEITFKNNALLLQVKKASMGDAG 1052
G + + G+ ++ W + + P + + L + D G
Sbjct: 365 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVG 424
Query: 1053 LYTCKVSNDAGSALCTSSIVIKE---PKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
Y C+ N AGS + + + + + + PPV Q TV+ LSC GS
Sbjct: 425 YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVP 484
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
I W K G + D NG VL+ + D G Y C AS +G T
Sbjct: 485 TILWRKDGVLVSTQDSRIKQLENG--VLQIRYAKLGDTGRYTCIASTPSGEAT 535
Score = 133 bits (335), Expect = 5e-31
Identities = 137/536 (25%), Positives = 215/536 (40%), Gaps = 25/536 (4%)
Frame = +3
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGR 383
+NS+G S ++++ PP D+ + G P C G ++ W+K G
Sbjct: 51 DNSLGYTGSR----LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGE 106
Query: 384 PL---KDGPNIQTSFLDNVATLNIF----QTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+ KD P L + + + + R G Y C A N +G A S +
Sbjct: 107 RVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVA 166
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIK-VAWAKDNREIRS--------GGNY 695
F P + V VGE A EC P ++W KD + GG
Sbjct: 167 ILRDDFRQNP-SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKL 225
Query: 696 QISYLENSAHLTILKVDKGDTGQYTCYAVNEVG-KDSCTAQLNIKERLIPPSFTKKLSE- 869
I+Y K D G+Y C N VG ++S A+L + ER PSF K+ S
Sbjct: 226 MITYTR-----------KSDAGKYVCVGTNMVGERESEVAELTVLER---PSFVKRPSNL 271
Query: 870 TVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDA 1049
V + F+ E R G +V W K++ E+ P + EI + L+++K + GD
Sbjct: 272 AVTVDDSAEFKCEAR--GDPVPTVRWRKDDGEL-PKSRYEIRDDHT---LKIRKVTAGDM 325
Query: 1050 GLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRI 1229
G YTC N G A ++++ ++E PP F V+ G + C G+ I
Sbjct: 326 GSYTCVAENMVGKAEASATLTVQE---PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAI 382
Query: 1230 QWLKAGRE-----IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS- 1391
W + G + +P S + T L +V ++D G Y+C+ NVAGS +K+
Sbjct: 383 FWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAY 442
Query: 1392 -KVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG 1568
+VT V+ Q++ V + +A G P+P + W K
Sbjct: 443 LEVTDVIADRPPPVIRQGPVN---------QTVAVDGTFVLSCVAT--GSPVPTILWRKD 491
Query: 1569 KWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
Q RI ++ + L+IR D+G Y ANCEITFKNNAL 1013
P S+ EE S ++E +G+ W K+ + + + F+++
Sbjct: 2868 PVIKGANSDLPEEVTVLVNKSTQMECSSSGNPAPRNYWQKDGQILLEDEHHK--FQSDGR 2925
Query: 1014 LLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQL 1193
LQ+ A + D G Y C N AGSA ++ + P P V + ++V F+ L
Sbjct: 2926 SLQILNAQITDTGRYVCVAENTAGSAKKYFNLNVHVP--PSVIGPNHEHLSVVVNHFISL 2983
Query: 1194 SCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAG 1373
+C V G P + WLK IKP+ + G L+ +D GDY C A N AG
Sbjct: 2984 NCEVSGFPPPDLSWLKNEEPIKPN--TNVLTVPGGRTLQIIRAKISDGGDYTCIAINQAG 3041
Query: 1374 SDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSI-RVVEKTTATFIAKVGGDPIPN 1550
K +T S+ SI V E T+ + + P P
Sbjct: 3042 ESKKKVSLTVHVPPSIKDHG------------SQSLSIVNVREGTSVSLECESNAVPPPV 3089
Query: 1551 VKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ W+K R + + I G L IR +D+G Y C A N G + N +L V
Sbjct: 3090 ITWSK-NGRMIPDSTNVEILTGGQ--TLHIRRAEVSDTGQYVCRAINVAGRDDKNFHLNV 3146
Score = 151 bits (381), Expect = 2e-36
Identities = 151/598 (25%), Positives = 243/598 (40%), Gaps = 15/598 (2%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V +GD+ ++C+ +G P V W+KGD +LRP+ + V L + D+G+Y
Sbjct: 713 VALGDTTVMECKTSGIPPPQVKWFKGDLELRPSTF--LSIDPLVGLLKIQETQDLDAGDY 770
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A N G + L V PP F ++ DV +G V C V G + W
Sbjct: 771 TCVAINEAGRATGRLTLDVGS---PPVFIQEPSDVAVEIGSNVTLPCYVQGYPEPKIKWR 827
Query: 372 K-DGRPLKDGPNIQTSFLDNVATLNIFQTD--RSFAGQYSCTATNPIGSASSSARLILTE 542
+ D P+ P SF+ + T +F ++ S G Y C A N G S + +T
Sbjct: 828 RLDNMPVFSRP-FSVSFISQLRTGALFISNLWASDKGTYICEAENQFGKIQSQTTVTVT- 885
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
G P I + + G+ C + PI N + Y + S
Sbjct: 886 GLVAPLIGISPSMASVIEGQPLTLPCTLLAGNPIPERRWMKNSAMLVQNPYITVRSDGSL 945
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
H+ +++ G G+YTC A N G ++ T + + + PS + + + EG
Sbjct: 946 HIERVRLQDG--GKYTCVASNVAGTNNKTTSVAVH---VLPSI-QHGQQILSTIEGVPVT 999
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L R +G S+ W K E+ T++ + + + L V S ++G Y C +N A
Sbjct: 1000 LPCRASGIPKPSITWSKKG-ELISTSSAKFSAGADGSLYVVSPGS-EESGEYICTATNAA 1057
Query: 1083 GSALCTSSIVIKEPKKPPVF-DQH------LTPVTVSEGEFLQLSCHVRGSEPIRIQWLK 1241
G A + + +P VF DQ ++V GE L C + P I W K
Sbjct: 1058 GYA--KRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEAILPCEAKSLPPPIITWAK 1115
Query: 1242 AGREIKP-SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXX 1418
+ I P S R +F + + E + +D+G Y+C A+N+AG+ T K++
Sbjct: 1116 DSQLISPFSPRHTFLPSGSMKITETR---VSDSGMYLCVATNIAGNVTQSVKLS------ 1166
Query: 1419 XXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR 1598
V K+ + ++V ++ + G P P + W K GR
Sbjct: 1167 -------VHVPPKIQHGNRHIKVQVGQR--VDILCNAHGSPPPVITWFK--------SGR 1209
Query: 1599 IFI----HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIE 1760
F+ H + L I +D+G+Y C A N G E+ V L V E E ++
Sbjct: 1210 PFLDGAQHPGSPDGTLSIEQAVISDAGVYTCAATNIAGSDEAEVTLHVQEPPSVEDLQ 1267
Score = 148 bits (374), Expect = 1e-35
Identities = 141/529 (26%), Positives = 220/529 (41%), Gaps = 3/529 (0%)
Frame = +3
Query: 156 FNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECA 335
F +V +D G Y C A +S G + TF V E PP + +V T G V C
Sbjct: 486 FTKVTLSDEGFYDCIAVSSAGTGRAQTFFDVSE---PPPIIQLPNNVTVTPGERAVLACL 542
Query: 336 VSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
V + +++W + GR ++ + + L N+ +L + AG+Y C ++ GSA+
Sbjct: 543 VISAVDYNLTWQRSGRDIRLADSARIRTLANL-SLELRSVKIGDAGEYRCVVSSEGGSAA 601
QueryC+A GE + ++V E
Sbjct: 492 GVLVSTQDSRI---KQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQE 544
Score = 119 bits (297), Expect = 1e-26
Identities = 94/287 (32%), Positives = 133/287 (46%), Gaps = 10/287 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VTV DSA +C+ G P V W K D +L P + Y++ + TL +V + D G Y
Sbjct: 273 VTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDDH---TLKIRKVTAGDMGSY 328
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C AEN VG+ +S LTVQE PP F + RD +G V F+C +G+ ++ W
Sbjct: 329 TCVAENMVGKAEASATLTVQE---PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR 385
Query: 372 KDGRP----LKDGPNIQTSF-LDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
++G P + F + L I RS G Y C N GS + A L +
Sbjct: 386 REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV 445
Query: 537 TE---GRNPPFFDIPLAPVDAVVGESADF--ECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
T+ R PP I PV+ V F C TG+ + W KD + S + +I
Sbjct: 446 TDVIADRPPPV--IRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDG-VLVSTQDSRI 502
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP 842
LEN L I GDTG+YTC A G+ + +A + ++E +P
Sbjct: 503 KQLENGV-LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVP 548
>ref|NP_598334.2| roundabout homolog 1 isoform b [Homo sapiens].
Length = 1606
Score = 156 bits (394), Expect = 8e-38
Identities = 136/473 (28%), Positives = 194/473 (41%), Gaps = 16/473 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKG----DTKLRPTATYKMHFRNN---VATLVFNQVD 170
V+ G+ A+L C+ G P + WYKG +T +++M + +V +
Sbjct: 40 VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 99
Query: 171 SNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
D G Y+C A N +GE S +++ L F + DV VG P V EC
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHN-ASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGH 158
Query: 351 P-ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSAR 527
P ++SW KDG PL D T L I T +S AG+Y C TN +G S
Sbjct: 159 PEPTISWKKDGSPLDDKDERITI---RGGKLMITYTRKSDAGKYVCVGTNMVGERESEV- 214
Query: 528 LILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISY 707
LT P F P + + V +SA+F+C G V W KD+ E+ Y+I
Sbjct: 215 AELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRYEI-- 270
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
+ L I KV GD G YTC A N VGK +A L ++ PP F K + V
Sbjct: 271 -RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVAL- 328
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVE-----IHPTANCEITFKNNALLLQVKKASMGDAG 1052
G + + G+ ++ W + + P + + L + D G
Sbjct: 329 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVG 388
Query: 1053 LYTCKVSNDAGSALCTSSIVIKE---PKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
Y C+ N AGS + + + + + + PPV Q TV+ LSC GS
Sbjct: 389 YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVP 448
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
I W K G + D NG VL+ + D G Y C AS +G T
Sbjct: 449 TILWRKDGVLVSTQDSRIKQLENG--VLQIRYAKLGDTGRYTCIASTPSGEAT 499
Score = 134 bits (336), Expect = 4e-31
Identities = 132/522 (25%), Positives = 209/522 (40%), Gaps = 25/522 (4%)
Frame = +3
Query: 246 VQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPL---KDGPNIQTS 416
++++ PP D+ + G P C G ++ W+K G + KD P
Sbjct: 22 LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81
Query: 417 FLDNVATLNIF----QTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPV 584
L + + + + R G Y C A N +G A S + F P + V
Sbjct: 82 LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNP-SDV 140
Query: 585 DAVVGESADFECHVTGTQPIK-VAWAKDNREIRS--------GGNYQISYLENSAHLTI: 516 SSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNY 695
+S L + E P + G C TG K+ W + I Y
Sbjct: 602 ASVFLTVQE---KPKVTVMPKNQSFTGGSEISIMCSATGYPKPKIVWTMNEMFIMGSHRY 658
Query: 696 QISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETV 875
+++ + L I D G Y C A N G D T+ L E P + SE +
Sbjct: 659 RMT---SEGTLFIKNAVPKDAGTYACLASNAAGTDKQTSTLRYIE---APKLVVEQSELL 712
Query: 876 EETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGL 1055
G++ +E + +G P V W+K ++E+ P+ ++ LL++++ DAG
Sbjct: 713 VAL-GDTTVMECKTSGIPPPQVKWFKGDLELRPST--FLSIDPLVGLLKIQETQDLDAGD 769
Query: 1056 YTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQW 1235
YTC N+AG A T + + + PPVF Q + V V G + L C+V+G +I+W
Sbjct: 770 YTCVAINEAGRA--TGRLTL-DVGSPPVFIQEPSDVAVEIGSNVTLPCYVQGYPEPKIKW 826
Query: 1236 LKAGREIKPSDRCSFSFAN--GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXX 1409
+ S S SF + T L ++ +D G Y+C+A N G S++ VT
Sbjct: 827 RRLDNMPVFSRPFSVSFISQLRTGALFISNLWASDKGTYICEAENQFGKIQSQTTVT--- 883
Query: 1410 XXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATF-IAKVGGDPIPNVKWTKGKWRQLN 1586
+ L +S P V+E T + G+PIP +W K L
Sbjct: 884 ---------VTGLVAPLIGIS-PSMASVIEGQPLTLPCTLLAGNPIPERRWMKNS-AMLV 932
Query: 1587 QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
Q I + G L I D G Y CVA N G ++ V+
Sbjct: 933 QNPYITVRSDG---SLHIERVRLQDGGKYTCVASNVAGTNNKTTSVAVH 978
Score = 147 bits (372), Expect = 2e-35
Identities = 146/581 (25%), Positives = 224/581 (38%), Gaps = 15/581 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ V G S SL+C++ G P+ V+W K L T + + L V +D+G
Sbjct: 2301 ITVIRGKSISLECEVQGIPQPTVTWMKDGRPL--TKGKGVEILDEGRILQLKNVHVSDTG 2358
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGL----PVVFECAVSGSEP 353
Y+C A N G L+V PPS V E V + V C SG
Sbjct: 2359 RYVCVAVNVAGMTDKRYDLSVHA---PPSIIGN-HGVPENVSVVEKSSVSLTCEASGIPL 2414
Query: 354 ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
S++W KDG P+ G +++ L L + QT AGQY+C N G L
Sbjct: 2415 PSITWLKDGWPVNLGSSVK--ILSGGRMLRLMQTRPEDAGQYTCIVRNAAGEDRKMFGLS 2472
Query: 534 LTEGRNPPFF--DIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISY 707
+ PP + L V +S C V G ++ W KD + ++ + +
Sbjct: 2473 VLV---PPHIVGENTLEDVKIKEKQSVTLTCEVRGNPVPQITWHKDGQLLQEDEAHHM-- 2527
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
+ L I TG+YTC A N G S + +LN+ + P+ S+ E
Sbjct: 2528 MSGGRFLQITNAQVSHTGRYTCLASNIAGDKSKSFRLNV---FVSPTIAGVDSDGSPEDV 2584
Query: 888 ----GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGL 1055
+ L P ++ W+K+ + N I LQ+ A +AG
Sbjct: 2585 IVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGR 2642
Query: 1056 YTCKVSNDAGSALCTSSIVIKEP---KKPPVFDQHLTP--VTVSEGEFLQLSCHVRGSEP 1220
Y+C +N+AG + + + P KK + L+P V + L L C
Sbjct: 2643 YSCVATNEAGEKIKHYEVKVYIPPIIKKGDLLGPGLSPKEVKIRVNSSLTLECEAYAIPS 2702
Query: 1221 IRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
++W K G+ +K D + + + T L+ K+ +D G Y C ASN+AG D V
Sbjct: 2703 ASLRWYKDGQPLKSDDHVTIAASGHT--LQIKEAQISDTGRYTCVASNLAGEDELDFDVN 2760
Query: 1401 XXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQ 1580
+ L ++ V+ + + P P + W K R
Sbjct: 2761 ---IQVPPSFQKLWEIGNMLDTGRSGEAKDVIINNPLSLHCETNAAPPPTLTWYK-DGRP 2816
Query: 1581 LNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
L R+ I G L+I D+G Y CVA N+ GE
Sbjct: 2817 LTSSDRVLILPGG--RVLQIPRAKVEDAGRYTCVAVNEAGE 2855
Score = 142 bits (359), Expect = 7e-34
Identities = 135/567 (23%), Positives = 219/567 (38%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVL 737
VGE A EC P ++W KD + GG I+Y
Sbjct: 141 MVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTR-------- 192
Query: 738 KVDKGDTGQYTCYAVNEVG-KDSCTAQLNIKERLIPPSFTKKLSE-TVEETEGNSFRLEG 911
K D G+Y C N VG ++S A+L + ER PSF K+ S V + F+ E
Sbjct: 193 ---KSDAGKYVCVGTNMVGERESEVAELTVLER---PSFVKRPSNLAVTVDDSAEFKCEA 246
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
R G +V W K++ E+ P + EI + L+++K + GD G YTC N G A
Sbjct: 247 R--GDPVPTVRWRKDDGEL-PKSRYEIRDDHT---LKIRKVTAGDMGSYTCVAENMVGKA 300
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE-----I 1256
++++ ++ +PP F V+ G + C G+ I W + G +
Sbjct: 301 EASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSY 360
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS--KVTXXXXXXXXXX 1430
+P S + T L +V ++D G Y+C+ NVAGS +K+ +VT
Sbjct: 361 QPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPV 420
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
V+ Q++ V + +A G P+P + W K Q RI
Sbjct: 421 IRQGPVN---------QTVAVDGTFVLSCVAT--GSPVPTILWRKDGVLVSTQDSRI--- 466
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
++ + L+IR D+G Y C+A GE + ++V E
Sbjct: 467 KQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQE 508
Score = 119 bits (299), Expect = 8e-27
Identities = 93/287 (32%), Positives = 132/287 (45%), Gaps = 10/287 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VTV DSA +C+ G P V W K D +L P + Y++ + TL +V + D G Y
Sbjct: 234 VTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDDH---TLKIRKVTAGDMGSY 289
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C AEN VG+ +S LTVQ PP F + RD +G V F+C +G+ ++ W
Sbjct: 290 TCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR 349
Query: 372 KDGRP----LKDGPNIQTSF-LDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
++G P + F + L I RS G Y C N GS + A L +
Sbjct: 350 REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV 409
Query: 537 TE---GRNPPFFDIPLAPVDAVVGESADF--ECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
T+ R PP I PV+ V F C TG+ + W KD + S + +I
Sbjct: 410 TDVIADRPPPV--IRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDG-VLVSTQDSRI 466
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP 842
LEN L I GDTG+YTC A G+ + +A + ++E +P
Sbjct: 467 KQLENGV-LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVP 512
>ref|XP_003403872.1| PREDICTED: hemicentin-2-like [Homo sapiens].
Length = 1215
Score = 154 bits (388), Expect = 4e-37
Identities = 161/617 (26%), Positives = 245/617 (39%), Gaps = 8/617 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V+ G++A L C++ G ++W + D ++ P +T ++ +++ L + + D G
Sbjct: 409 VTVSPGETAVLSCRVLGEAPYNLTWVR-DWRVLPASTGRVAQLADLS-LEISGIIPTDGG 466
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C A N+ G +S +L V+E P S + G+ V C+ SG +S
Sbjct: 467 RYQCVASNANGVTRASVWLLVREA---PQVSIHTSSQHFSQGVEVKVSCSASGYPTPHIS 523
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W ++ + L++ I +D TL I AG YSC ATN +G+ + L T+
Sbjct: 524 WSRESQALQEDSRIH---VDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTD- 579
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP A V VGE A C +G P +V W + GG I E S+
Sbjct: 580 --PPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYR-------GGLEMILAPEGSSS 630
Query: 726 --LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I + D G YTC AVNE+G S QL + P T +L V G S
Sbjct: 631 GKLRFNQVDSNDSGEYICRAENS 212
+L+C+ P + W K +L+ AT ++ + L N D D+ Y C A N
Sbjct: 3639 TLECKSDAVPPPVIMWLKNREQLQ--ATPRVRILSGGRYLQINNADLGDTANYTCVASNI 3696
Query: 213 VGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLK 392
G+ + LTV +PPS + + + + EC G ++W KDG L
Sbjct: 3697 AGKTTREFNLTVN---VPPSIGGGPQSLVTLLNKSIALECRAEGVPAPRITWRKDGVVLA 3753
Query: 393 DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIP 572
+ + + S L+N L+I + G+Y C ATN G+ R I + PP +
Sbjct: 3754 ES-HARYSILEN-GFLHIESAHVTDTGRYLCMATNVAGT---DRRRIDLQVHVPPSIAMG 3808
Query: 573 LAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKG 752
V V C TG V W K+ + N L +S L I+
Sbjct: 3809 PTNVTVTVNVQTTLACEATGIPKPSVTWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVD 3868
Query: 753 DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQP 932
DT Y C ++ G+D L ++ +PP+ + + + + + + +G
Sbjct: 3869 DTASYECTVTSDAGEDKRAVDLTVQ---VPPTIADEPMDFLVTRQAPAV-MTCSASGVPV 3924
Query: 933 ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIV 1112
S+ W KN + + P + + A +++ + AG YTC N AGSA ++
Sbjct: 3925 PSIHWTKNGLRLLPRGDGYRILSSGA--IEIPTTQLNHAGRYTCVARNAAGSAHRHVTLR 3982
Query: 1113 IKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFAN 1292
++E PPV + + V + L C G I W K G + S + +
Sbjct: 3983 VQE---PPVIQPQPSELDVILNNPILLPCEATGIPTPFITWQKEGINVITSGKSLAILPS 4039
Query: 1293 GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVS 1472
G+ L+ + DAG Y+C A N AG+ K K+ V S
Sbjct: 4040 GS--LQISRAVRGDAGTYMCVAQNPAGTALGKVKLN---------------VQVPPVISS 4082
Query: 1473 EPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTT 1652
+ V + + + G P P++ W K L + R I G L+I
Sbjct: 4083 HQKEYVVTMDKPVSLLCETEGSPPPDITWHK-DGHALTESIRQRILNSG---ALQIAFAQ 4138
Query: 1653 KTDSGLYRCVAFNKHGEIESNVNLQVN 1733
D+G Y C+A N G + L V+
Sbjct: 4139 PDDAGQYTCMAANMAGSSSVSSTLTVH 4165
Score = 142 bits (358), Expect = 1e-33
Identities = 150/569 (26%), Positives = 222/569 (39%), Gaps = 4/569 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V + + L C+ G P ++W K + + + +L ++ D+G Y
Sbjct: 3998 VILNNPILLPCEATGIPTPFITWQKEGINVITSGKSLAILPSG--SLQISRAVRGDAGTY 4055
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
+C A+N G L VQ +PP S ++ T+ PV C GS P ++W
Sbjct: 4056 MCVAQNPAGTALGKVKLNVQ---VPPVISSHQKEYVVTMDKPVSLLCETEGSPPPDITWH 4112
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDG L + +I+ L N L I AGQY+C A N GS+S S+ L +
Sbjct: 4113 KDGHALTE--SIRQRIL-NSGALQIAFAQPDDAGQYTCMAANMAGSSSVSSTLTV---HV 4166
Query: 552 PPFFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDNREIRSG-GNYQISYLENSA 722
PP I V V E++ C G + W KD I + G Y +
Sbjct: 4167 PP--RIQSTEVHFTVNENSQAVLPCVADGIPTPAIHWEKDGVLIANLLGKYTA---QPYG 4221
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + V D+G YTC A N G+D+ L + P+FT+ L + +G R
Sbjct: 4222 ELILENVVLEDSGTYTCVANNAAGEDTRIVTLAVHTL---PTFTE-LPGDLSLNKGEQLR 4277
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L + G + W NN I P I N L ++K S D+G Y C N
Sbjct: 4278 LSCKAVGIPLPKLTWTFNN-NIIPAHFDSI---NGHSELVIEKVSKEDSGTYVCTAENSV 4333
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSE-GEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
G + +KE PPVF + G L+C V+G IQW + G +I+
Sbjct: 4334 GFVKAIGFVYVKE---PPVFKGDYPSNWIEPLGGNAILNCEVKGDPAPTIQWSRKGADIE 4390
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
S R NG+ L DAGDY C A+N AG +T
Sbjct: 4391 ISHRIR-QLGNGS--LAIYGTVNEDAGDYTCVAANEAGMVERSMSLT--------IPAAQERDAGTYTCRAVNELGDASAEIQLAVGH---APQLT-ELPRDVTVELGRSA 686
Query: 900 RLEGRVAGSQPISVAWYKNN-----VEIHPTANCEITFKNNALLLQVKKASMGDAGLYTC 1064
L R G P +V W + + + + ++ +L + + D Y C
Sbjct: 687 LLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLF-FESVAPEDQAPYVC 745
Query: 1065 KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI-RIQWLK 1241
+ N G + +++ PP V V EG+ + L C V P+ WLK
Sbjct: 746 EARNVFGKVQAEARLIV-TGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLK 804
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
GR + P R S A+G+ L + AG Y C A+N AGS ++
Sbjct: 805 DGRPLPPGSRHSIR-ADGS--LHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRI 861
Query: 1422 XXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRI 1601
+ E A+ G P P + WTK ++G
Sbjct: 862 HPTATHHITN---------------EGVPASLPCVASGVPAPTITWTKETNALTSRGPHY 906
Query: 1602 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAML 1781
+ ++G L I + D+G Y C A N G + L VN K + + G A +
Sbjct: 907 NVSKEG---TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVN-TKPRIHMNGSRNANV 962
Query: 1782 KKTPVLKKGAGEEEEID 1832
K AGEE +D
Sbjct: 963 PLQVTAK--AGEEVTLD 977
Score = 135 bits (339), Expect = 2e-31
Identities = 128/481 (26%), Positives = 189/481 (39%), Gaps = 24/481 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTK--LRPTATYKMHFRNNVATLVFNQVDSND 179
V V VG+ A L C+ +G P V WY+G + L P + R A D
Sbjct: 590 VLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSSGKLRIPAA-------QERD 642
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
+G Y CRA N +G+ S+ L V P + RDV +G + C +G P +
Sbjct: 643 AGTYTCRAVNELGDASAEIQLAVGHA---PQLTELPRDVTVELGRSALLACRATGRPPPT 699
Query: 360 VSWFK-DGRPL-----------KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPI 503
V+W + DG+PL P+ F ++VA + Y C A N
Sbjct: 700 VTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPED--------QAPYVCEARNVF 751
Query: 504 GSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVA-WAKDNREIR 680
G + ARLI+T G PP V + G+ C V +P+ W KD R +
Sbjct: 752 GKVQAEARLIVT-GHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLP 810
Query: 681 SGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKK 860
G + I + S HL + + G+Y+C A N G +L ++ +PP
Sbjct: 811 PGSRHSIR-ADGSLHLD--RALQEHAGRYSCVATNTAGSQHRDVELVVQ---VPPRIHPT 864
Query: 861 LSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASM 1040
+ + EG L +G ++ W K + K LL + + S
Sbjct: 865 ATHHITN-EGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLL--IAQPSA 921
Query: 1041 GDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT---------PVTVSEGEFLQL 1193
DAG Y C +N G + + + + KP + H+ VT GE + L
Sbjct: 922 QDAGAYVCTATNTVGFS--SQEMRLSVNTKPRI---HMNGSRNANVPLQVTAKAGEEVTL 976
Query: 1194 SCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAG 1373
C +GS P + W K R + P +G+ L V D+G Y C ASN AG
Sbjct: 977 DCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGS--LRLAQVQVGDSGHYECTASNPAG 1034
Query: 1374 S 1376
S
Sbjct: 1035 S 1035
Score = 134 bits (337), Expect = 3e-31
Identities = 147/579 (25%), Positives = 211/579 (36%), Gaps = 6/579 (1%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G + C +G P +SW + L+ + + + TL+ V D+G Y C+
Sbjct: 505 GVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQG---TLIIQGVAPEDAGNYSCQ 561
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A N VG + L + PPS S V VG V C SG P V W++ G
Sbjct: 562 ATNEVGTDQETVTLYYTD---PPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGG 618
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ P +S L I AG Y+C A N +G AS+ +L + G P
Sbjct: 619 LEMILAPEGSSS-----GKLRIPAAQERD----- 4434
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
+ EP V + G+P P + W++ + + ++ R+ +
Sbjct: 4435 --LQSSPIITLEPVETVVDAGGRVILDCQAAGEPQPTITWSR-QGQPISWDNRLSML--- 4488
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEI 1706
+ L I K D+ Y CVA N G +
Sbjct: 4489 PNSSLYIAAARKEDTSEYECVARNLMGSV 4517
Score = 141 bits (355), Expect = 2e-33
Identities = 140/578 (24%), Positives = 225/578 (38%), Gaps = 8/578 (1%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G+ +L C+ +G P ++W K + + + ++H + L + + D+G Y C
Sbjct: 2210 GNLITLLCESSGIPPPDLTWKKKGSLVLADSAGRVHILSGGRRLQISIAEKADAGLYTCV 2269
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A N G L V + + ++ G + EC V G +V+W KDG
Sbjct: 2270 ASNVAGVAKKEYNLQVYIRPSITNSGGHRPEITVIRGKSISLECEVQGIPQPTVTWMKDG 2329
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
RPL G ++ LD L + S G+Y C A N G R L+ P
Sbjct: 2330 RPLTKGKGVE--ILDEGRILQLKNVHVSDTGRYVCVAVNVAGMTDK--RYDLSVHAPPSI 2385
Query: 561 FDIPLAP--VDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTI 734
P V V S C +G + W KD + G + +I L L +
Sbjct: 2386 IGNHGVPENVSVVEKSSVSLTCEASGIPLPSITWLKDGWPVNLGSSVKI--LSGGRMLRL 2443
Query: 735 LKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKLSETVEETEGNSFRLEG 911
++ D GQYTC N G+D L++ L+PP + E V+ E S L
Sbjct: 2444 MQTRPEDAGQYTCIVRNAAGEDRKMFGLSV---LVPPHIVGENTLEDVKIKEKQSVTLTC 2500
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
V G+ + W+K+ + + + LQ+ A + G YTC SN AG
Sbjct: 2501 EVRGNPVPQITWHKDGQLLQEDEAHHMM--SGGRFLQITNAQVSHTGRYTCLASNIAGDK 2558
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTP--VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
+ + + D +P V V L C P I W K G ++ S
Sbjct: 2559 SKSFRLNVFVSPTIAGVDSDGSPEDVIVILNSPTSLVCEAYSYPPATITWFKDGTPLE-S 2617
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+R + G L+ + + +AG Y C A+N AG +V
Sbjct: 2618 NR-NIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEKIKHYEVKVYIPPIIKK------ 2670
Query: 1446 VDGKLFFVS-EPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
G L P+ +++ ++ T + P +++W K + L + I G
Sbjct: 2671 --GDLLGPGLSPKEVKIRVNSSLTLECEAYAIPSASLRWYKDG-QPLKSDDHVTIAASGH 2727
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHG--EIESNVNLQV 1730
L+I++ +D+G Y CVA N G E++ +VN+QV
Sbjct: 2728 T--LQIKEAQISDTGRYTCVASNLAGEDELDFDVNIQV 2763
Score = 140 bits (352), Expect = 5e-33
Identities = 147/611 (24%), Positives = 247/611 (40%), Gaps = 6/611 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT G+ A L C + + ++W + +R + ++ N++ L V D+G
Sbjct: 529 VTVTPGERAVLACLVISAVDYNLTWQRSGRDIRLADSARIRTLANLS-LELRSVKIGDAG 587
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY C + G ++S FLTVQE+ P + ++ T G + C+ +G +
Sbjct: 588 EYRCVVSSEGGSAAASVFLTVQEK---PKVTVMPKNQSFTGGSEISIMCSATGYPKPKIV 644
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W + + + + + TL I AG Y+C A+N G+ ++ L E
Sbjct: 645 WTMNEMFIMGSHRYR---MTSEGTLFIKNAVPKDAGTYACLASNAAGTDKQTSTLRYIEA 701
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P + + + +G++ EC +G P +V W K + E+R I L
Sbjct: 702 ---PKLVVEQSELLVALGDTTVMECKTSGIPPPQVKWFKGDLELRPSTFLSIDPLVGL-- 756
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L I + D G YTC A+NE G+ + L++ PP F ++ S+ E G++ L
Sbjct: 757 LKIQETQDLDAGDYTCVAINEAGRATGRLTLDVGS---PPVFIQEPSDVAVEI-GSNVTL 812
Query: 906 EGRVAGSQPISVAWYK-NNVEI--HPTANCEIT-FKNNALLLQVKKASMGDAGLYTCKVS 1073
AGTYTCRAVNELGDASAEIQLAV--GHAPQL 671
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE---IRSG-GNYQISYLENSAHL 728
++P V +G SA C TG P V W + + + +R G G S +S L
Sbjct: 672 TELP-RDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVL 730
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
V D Y C A N GK A+L + PP + TV EG L
Sbjct: 731 FFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHA-PPQIASS-APTVRVLEGQPVSLP 788
Query: 909 GRVAGSQPISVA-WYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
V +P+ W K+ + P + I + L + +A AG Y+C +N AG
Sbjct: 789 CIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGS---LHLDRALQEHAGRYSCVATNTAG 845
Query: 1086 SALCTSSIVIKEPKK-PPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
S +V++ P + P H+T +EG L C G I W K +
Sbjct: 846 SQHRDVELVVQVPPRIHPTATHHIT----NEGVPASLPCVASGVPAPTITWTKETNAL-- 899
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ R + L + DAG YVC A+N G + + +++
Sbjct: 900 TSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRN 959
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+ P + T + G P P V WTK R + G
Sbjct: 960 --------ANVPLQVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSG- 1010
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
L + DSG Y C A N G L V R
Sbjct: 1011 --SLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQGR 1047
Score = 125 bits (315), Expect = 1e-28
Identities = 110/371 (29%), Positives = 152/371 (40%), Gaps = 9/371 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTK---LRPTATYKMHFRN-NVATLVFNQVDS 173
V V +G SA L C+ G P V+W +GD + LR A R + L F V
Sbjct: 678 VTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAP 737
Query: 174 NDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEP 353
D Y+C A N G+V + L V PP + V+ G PV C V P
Sbjct: 738 EDQAPYVCEARNVFGKVQAEARLIVTGHA-PPQIASSAPTVRVLEGQPVSLPCIVLAGRP 796
Query: 354 ISVS-WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
+ W KDGRPL G + +L++ + + AG+YSC ATN GS L
Sbjct: 797 LPERHWLKDGRPLPPGSRHS---IRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVEL 853
Query: 531 ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGG-NYQISY 707
++ + PP G A C +G + W K+ + S G +Y +S
Sbjct: 854 VV---QVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVS- 909
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQL--NIKERL-IPPSFTKKLSETVE 878
L I + D G Y C A N VG S +L N K R+ + S + V
Sbjct: 910 --KEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVT 967
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
G L+ GS P V W K++ + P N + +L L + +GD+G Y
Sbjct: 968 AKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGSLRLA--QVQVGDSGHY 1025
Query: 1059 TCKVSNDAGSA 1091
C SN AGSA
Sbjct: 1026 ECTASNPAGSA 1036
Score = 125 bits (313), Expect = 2e-28
Identities = 131/525 (24%), Positives = 204/525 (38%), Gaps = 7/525 (1%)
Frame = +3
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
+ G Y C A + G + + V + PP +V + G V C V G P
Sbjct: 373 EEGTYECTAVSRAGTGRAKAQIVVTD---PPPQLVPAPNVTVSPGETAVLSCRVLGEAPY 429
Query: 357 SVSWFKDGR--PLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
+++W +D R P G Q + L ++ I TD G+Y C A+N G +S L
Sbjct: 430 NLTWVRDWRVLPASTGRVAQLADL-SLEISGIIPTD---GGRYQCVASNANGVTRASVWL 485
Query: 531 ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
++ R P I + G C +G ++W+++++ ++ ++
Sbjct: 486 LV---REAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRI---HV 539
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEG 890
+ L I V D G Y+C A NEVG D T V G + W + +N+ + P + I+ + AL + AS D G Y C+
Sbjct: 813 PCYVQGYPEPKIKWRRLDNMPVFSRPFSVSFISQLRTGALFISNLWAS--DKGTYICEAE 870
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI-RIQWLKAGR 1250
N G +++ + P+ + +V EG+ L L C + PI +W+K
Sbjct: 871 NQFGKIQSQTTVTV-TGLVAPLIGISPSMASVIEGQPLTLPCTLLAGNPIPERRWMKNSA 929
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
+ + + L + V D G Y C ASNVAG++ + V
Sbjct: 930 MLVQN---PYITVRSDGSLHIERVRLQDGGKYTCVASNVAGTNNKTTSVAVHVLPSIQHG 986
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
Q + +E T + G P P++ W+K K ++ F
Sbjct: 987 ---------------QQILSTIEGVPVTLPCRASGIPKPSITWSK-KGELISTSSAKF-- 1028
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKT 1790
G + L + +SG Y C A N G + V L V R ++ GD R + +
Sbjct: 1029 SAGADGSLYVVSPGSEESGEYICTATNAAGYAKRKVQLTVYVR---PRVFGDQRGLSQDK 1085
Query: 1791 PV-LKKGAGEE 1820
PV + AGEE
Sbjct: 1086 PVEISVLAGEE 1096
Score = 124 bits (312), Expect = 2e-28
Identities = 139/584 (23%), Positives = 211/584 (36%), Gaps = 9/584 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRP-TATYKMHFRNNVATLVFNQVDSNDS 182
V V V + L C +G P +SW K RP T ++ A L + D+
Sbjct: 3537 VSVIVNNPLELSCIASGIPAPKISWMKDG---RPFLQTEQVQTLEGGAILRVSSAQVEDT 3593
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSR--QLRDVQETVGLPVVFECAVSGSEPI 356
G Y C A + G+ + V +PP+ + + +D V EC P
Sbjct: 3594 GRYTCLASSPAGDDDKEYLVRVH---VPPNIAGMDEAQDFTVLRNRQVTLECKSDAVPPP 3650
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
+ W K+ L+ P ++ L L I D Y+C A+N G + L +
Sbjct: 3651 VIMWLKNREQLQATPRVR--ILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFNLTV 3708
Query: 537 TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
PP + ++ +S EC G ++ W KD + + + + S LEN
Sbjct: 3709 NV---PPSIGGGPQSLVTLLNKSIALECRAEGVPAPRITWRKDG-VVLAESHARYSILEN 3764
Query: 717 ------SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE 878
SAH+T DTG+Y C A N G D L + +PPS V
Sbjct: 3765 GFLHIESAHVT-------DTGRYLCMATNVAGTDRRRIDLQVH---VPPSIAMG-PTNVT 3813
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
T L G SV W KN ++ N ++ L + S+ D Y
Sbjct: 3814 VTVNVQTTLACEATGIPKPSVTWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTASY 3873
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWL 1238
C V++DAG + ++ P P + D+ + + + + ++C G I W
Sbjct: 3874 ECTVTSDAGEDKRAVDLTVQVP--PTIADEPMDFLVTRQAPAV-MTCSASGVPVPSIHWT 3930
Query: 1239 KAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXX 1418
K G + P ++G +E AG Y C A N AGS + VT
Sbjct: 3931 KNGLRLLPRGDGYRILSSG--AIEIPTTQLNHAGRYTCVARNAAGS--AHRHVT------ 3980
Query: 1419 XXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR 1598
V +P + V+ + G P P + W K + G
Sbjct: 3981 -------LRVQEPPVIQPQPSELDVILNNPILLPCEATGIPTPFITWQKEGINVITSGKS 4033
Query: 1599 IFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ I G L+I + D+G Y CVA N G V L V
Sbjct: 4034 LAILPSG---SLQISRAVRGDAGTYMCVAQNPAGTALGKVKLNV 4074
Score = 101 bits (251), Expect = 2e-21
Identities = 100/373 (26%), Positives = 147/373 (39%), Gaps = 2/373 (0%)
Frame = +3
Query: 618 CHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT--ILKVDKGDTGQYTCYAVNEV 791
C V P +++ +D I G + YL SA + KV D G Y C AV+
Sbjct: 451 CSVESFLPFTLSFMRDG--IALGVD---QYLRESASVNWDFTKVTLSDEGFYDCIAVSSA 505
Query: 792 GKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIH 971
G ++ E PP + L V T G L V + ++ W ++ +I
Sbjct: 506 GTGRAQTFFDVSE---PPPIIQ-LPNNVTVTPGERAVLACLVISAVDYNLTWQRSGR L + PPS ++ V G
Sbjct: 540 DAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTD---PPS-VSAVNAVVLVAVG 595
Query: 891 NSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
L +G P V WY+ +E+ + K L++ A DAG YTC+
Sbjct: 596 EEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSSGK-----LRIPAAQERDAGTYTCRA 650
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKA-G 1247
N+ G A + + P + VTV G L+C G P + W + G
Sbjct: 651 VNELGDASAEIQLAVGH---APQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDG 707
Query: 1248 REI---KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXX 1418
+ + + R S S + VL F+ V D YVC+A NV G +++++
Sbjct: 708 QPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAP 767
Query: 1419 XXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKV-GGDPIPNVKWTKGKWRQLNQGG 1595
S ++RV+E + V G P+P W K R L G
Sbjct: 768 PQ-------------IASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLK-DGRPLPPGS 813
Query: 1596 RIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
R H + L + + +G Y CVA N G +V L V
Sbjct: 814 R---HSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVV 855
Score = 105 bits (261), Expect = 2e-22
Identities = 106/477 (22%), Positives = 190/477 (39%), Gaps = 5/477 (1%)
Frame = +3
Query: 315 PVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTAT 494
P++ C+V + P + + L + + Q S ++ I + ++ G Y CTA
Sbjct: 326 PLLVSCSVHSALPFRLQLRRGEARLGEERHFQES---GNSSWEILRASKAEEGTYECTAV 382
Query: 495 NPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE 674
+ G+ + A++++T+ PP +P V GE+A C V G P + W +D R
Sbjct: 383 SRAGTGRAKAQIVVTD---PPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRV 439
Query: 675 I--RSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPS 848
+ +G Q++ L L I + D G+Y C A N G + L ++E P
Sbjct: 440 LPASTGRVAQLADLS----LEISGIIPTDGGRYQCVASNANGVTRASVWLLVRE---APQ 492
Query: 849 FTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVK 1028
+ S + ++G ++ +G ++W + + + + + + L ++
Sbjct: 493 VSIHTS-SQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGT---LIIQ 548
Query: 1029 KASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVR 1208
+ DAG Y+C+ +N+ G+ T ++ + PP V V+ GE L C
Sbjct: 549 GVAPEDAGNYSCQATNEVGTDQETVTLYYTD---PPSVSAVNAVVLVAVGEEAVLVCEAS 605
Query: 1209 GSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSK 1388
G P R+ W + G E+ + S S L + DAG Y C+A N G +++
Sbjct: 606 GVPPPRVIWYRGGLEMILAPEGSSS-----GKLRIPAAQERDAGTYTCRAVNELGDASAE 660
Query: 1389 SKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG 1568
++ V P+ + V +A + G P P V W +G
Sbjct: 661 IQLA---------------VGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRG 705
Query: 1569 KWRQLN---QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ L GR ++ D L D Y C A N G++++ L V
Sbjct: 706 DGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIV 762
Score = 94.7 bits (234), Expect = 3e-19
Identities = 89/401 (22%), Positives = 159/401 (39%), Gaps = 7/401 (1%)
Frame = +3
Query: 618 CHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGK 797
C V P ++ + + ++Q S ++ IL+ K + G Y C AV+ G
Sbjct: 331 CSVHSALPFRLQLRRGEARLGEERHFQES---GNSSWEILRASKAEEGTYECTAVSRAGT 387
Query: 798 DSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPT 977
AQ+ + + PP + TV + G + L RV G P ++ W ++ + P
Sbjct: 388 GRAKAQIVVTDP--PPQLVPAPNVTV--SPGETAVLSCRVLGEAPYNLTWVRD-WRVLPA 442
Query: 978 ANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT 1157
+ + + L L++ D G Y C SN G + ++++E P H +
Sbjct: 443 STGRVAQLAD-LSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREA---PQVSIHTS 498
Query: 1158 PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADA 1337
S+G +++SC G I W + + ++ DIR 561
Query: 972 PTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQH 1151
+ I N L L+++ +GDAG Y C VS++ GSA + + ++E K V ++
Sbjct: 562 LADSARIRTLAN-LSLELRSVKIGDAGEYRCVVSSEGGSAAASVFLTVQEKPKVTVMPKN 620
Query: 1152 LTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKA 1331
+ + G + + C G +I W I S R + + GT L K+
Sbjct: 621 ---QSFTGGSEISIMCSATGYPKPKIVWTMNEMFIMGSHRYRMT-SEGT--LFIKNAVPK 674
Query: 1332 DAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTA 1511
DAG Y C ASN AG+D S + V E + V T
Sbjct: 675 DAGTYACLASNAAGTDKQTSTLRYIEAPK---------------LVVEQSELLVALGDTT 719
Query: 1512 TFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFN 1691
K G P P VKW KG L F+ L+I++T D+G Y CVA N
Sbjct: 720 VMECKTSGIPPPQVKWFKG---DLELRPSTFLSIDPLVGLLKIQETQDLDAGDYTCVAIN 776
Query: 1692 KHGEIESNVNLQV 1730
+ G + L V
Sbjct: 777 EAGRATGRLTLDV 789
>ref|XP_003084534.1| PREDICTED: hemicentin-2 [Mus musculus].
Length = 5042
Score = 174 bits (441), Expect = 2e-43
Identities = 160/592 (27%), Positives = 246/592 (41%), Gaps = 10/592 (1%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVA-----TLVFNQVDSNDSG 185
G++ASL C GTP+ ++W +G + + ++ R +VA +L + V DSG
Sbjct: 1270 GENASLPCPAQGTPKPRITWRRGPS------SEPLNGRPDVAVLDEGSLFLSSVSLADSG 1323
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQ--LRDVQETVGLPVVFECAVSGSEPIS 359
EY C+A N VG S L V +PPS + + +V G P+ EC ++G
Sbjct: 1324 EYECQATNEVGSASRRAKLVVY---VPPSIREEGHITNVSGLAGQPLTLECDINGFPAPE 1380
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V+W KDG+ + D + T I S +G YSC A N GSA L +
Sbjct: 1381 VAWLKDGQLVGDSGG---GWDGEGGTFGI---QESHSGLYSCQAENQAGSAQRDFNLAVF 1434
Query: 540 EGRNPPFFDIPLAP-VDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
P A V + G EC +G +V W KD + I G + I E+
Sbjct: 1435 IP--PSLLGAGAAQEVLGLAGADVTLECQTSGVPTPQVEWTKDGQPILPGDPH-ILLQED 1491
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET--EG 890
L I+ GD GQY C A + G+ + QL+I PP+ +ET E T EG
Sbjct: 1492 GQVLRIISSHLGDEGQYQCVAFSPAGQQAKDFQLSIHS---PPTIWGS-NETGEVTVLEG 1547
Query: 891 NSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
++ +L G ++ WYK+ + P++ E+ + LQ+ KA DAGLYTC+
Sbjct: 1548 HTAQLLCEARGMPSPAITWYKDGTLLAPSS--EVVYSKGGRQLQLVKAQPSDAGLYTCQA 1605
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
SN AG ++S+ + P D V G + L C RG P I W G
Sbjct: 1606 SNPAGITKKSTSLEVYVPPTIEGADGGPYLVQAVAGRPVALECVARGHPPPTISWQHEGL 1665
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
+ S+ ++ L+ ++ +A G Y C AS+ AG + V
Sbjct: 1666 PVVDSNG---TWLEAGGALQLENPGEASGGLYSCVASSPAGEAVLQYSV----------- 1711
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
V +L + + + G P+P ++W + R + + +
Sbjct: 1712 --EMQVPPQLLVAEGMGQVTATVGQSLDLPCQASGSPVPTIQWLQ-NGRPAEELAGVQLA 1768
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGD 1766
+G L I SGL+ C A N+ G + V + V+E I G+
Sbjct: 1769 SQG--TILHISHVELNHSGLFACQATNEAGTAGAEVEVSVHELPSVHIIGGE 1818
Score = 173 bits (439), Expect = 4e-43
Identities = 148/594 (24%), Positives = 241/594 (40%), Gaps = 28/594 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT+ + SL C+ P ++W K + A+ + L D+G
Sbjct: 2522 VTVTINNPISLICEALAFPSPNITWMKDGSPFE--ASKNIQLLPGTHGLQILNAQKEDAG 2579
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQ-------LRDVQETVGLPVVFECAVSG 344
+Y C N +GE + + + V +PPS S+ +++V+ V + EC R A GT +++ V DA
Sbjct: 499 SQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVD-AQGTLIIQ--GVAPEDA 555
Query: 1338 GDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTT--- 1508
G+Y C+A+N G+D + VT + ++P S+ V
Sbjct: 556 GNYSCQATNEVGTD--QETVT--------------------LYYTDPPSVSAVNAVVLVA 593
Query: 1509 ----ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYR 1676
A + + G P P V W +G I + KL I + D+G Y
Sbjct: 594 VGEEAVLVCEASGVPPPRVIWYRGGLEM------ILAPEGSSSGKLRIPAAQERDAGTYT 647
Query: 1677 CVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVL 1799
C A N+ G+ + + L V + ++ D+ L ++ +L
Sbjct: 648 CRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALL 688
Score = 94.0 bits (232), Expect = 5e-19
Identities = 84/286 (29%), Positives = 116/286 (40%), Gaps = 10/286 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQC-QLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
V+V G SL C LAG P W K L P + + + + L ++ +
Sbjct: 777 VRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGS---LHLDRALQEHA 833
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y C A N+ G L VQ +PP G+P C SG ++
Sbjct: 834 GRYSCVATNTAGSQHRDVELVVQ---VPPRIHPTATHHITNEGVPASLPCVASGVPAPTI 890
Query: 363 SWFKDGRPLKD-GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIG--------SAS 515
+W K+ L GP+ S TL I Q AG Y CTATN +G S +
Sbjct: 891 TWTKETNALTSRGPHYNVS---KEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVN 947
Query: 516 SSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNY 695
+ R+ + RN ++PL V A GE +C G+ P V W KD+R + N
Sbjct: 948 TKPRIHMNGSRNA---NVPL-QVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNR 1003
Query: 696 QISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKER 833
L S L + +V GD+G Y C A N G S L ++ R
Sbjct: 1004 Y--GLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQGR 1047
Score = 51.6 bits (122), Expect = 3e-06
Identities = 55/185 (29%), Positives = 82/185 (44%), Gaps = 1/185 (0%)
Frame = +3
Query: 1185 LQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASN 1364
L +SC V + P R+Q L+ G E + + F +G + E +KA+ G Y C A +
Sbjct: 327 LLVSCSVHSALPFRLQ-LRRG-EARLGEERHFQ-ESGNSSWEILRASKAEEGTYECTAVS 383
Query: 1365 VAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPI 1544
AG+ +K+++ D V P ++ V TA +V G+
Sbjct: 384 RAGTGRAKAQIVV--------------TDPPPQLVPAP-NVTVSPGETAVLSCRVLGEAP 428
Query: 1545 PNVKWTKGKWRQLNQG-GRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVN 1721
N+ W + WR L GR+ Q D LEI TD G Y+CVA N +G ++V
Sbjct: 429 YNLTWVRD-WRVLPASTGRVA--QLAD-LSLEISGIIPTDGGRYQCVASNANGVTRASVW 484
Query: 1722 LQVNE 1736
L V E
Sbjct: 485 LLVRE 489
>ref|NP_001380.2| Down syndrome cell adhesion molecule isoform CHD2-42 precursor [Homo
sapiens].
Length = 2012
Score = 154 bits (388), Expect = 4e-37
Identities = 150/579 (25%), Positives = 235/579 (40%), Gaps = 15/579 (2%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
K G L C+ G PE W K + L + F+ V L+ + +DSG
Sbjct: 235 KAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSG----RFQKTVTGLLIENIRPSDSGS 290
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y+C N G L V++ P + R V+ +VG V C+V+G+E +SW
Sbjct: 291 YVCEVSNRYGTAKVIGRLYVKQ---PLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSW 347
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+++G L G N++ + + N L + +S G Y C SA +++L +G
Sbjct: 348 YRNGEILNPGKNVRITGI-NHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGT 406
Query: 549 N---PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
F + ++P + V C+V GT + W D+ I GG+++IS + S
Sbjct: 407 PKIISAFSEKVVSPAEPV-----SLMCNVKGTPLPTITWTLDDDPILKGGSHRISQ
Sbjct: 2580 QYTCVVTNELGEATKNYHVEVL---IPPSISKDDPLGEVSVKEVKTKVNSSLTLECECWA 2636
Query: 345 SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
+ P S+SW+KDGRP+ P+ + S L L I T S +G+Y C ATN G
Sbjct: 2637 TPPPSISWYKDGRPVT--PSHRLSVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDF 2694
Query: 525 RLILTEGRNPPFFDIPLAPVDA---------------------VVGESADFECHVTGTQP 641
+++ + PP F + VDA V A C P
Sbjct: 2695 NVLI---QVPPMFQ-KMGDVDAGFEPLPHEEEAQGRVTEYREIVENNPAYLYCDTNAIPP 2750
Query: 642 IKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLN 821
++ W ++ + + + +S L+ L + V D G+Y+C A NEVG+D +L
Sbjct: 2751 PELTWYREGQPLSAADG--VSVLQGGRILQLPLVQAEDAGRYSCKAANEVGEDWLHYELL 2808
Query: 822 IKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFK 1001
+ + P T++L E V ++ LE G+ +V+W++N + + P+ ++
Sbjct: 2809 VLTPPVIPGDTQELVEEVTVNASSAVSLECPALGNPAPAVSWFQNGLPVSPSPRLQVL-- 2866
Query: 1002 NNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGE 1181
+L+V A + DA Y C N AGSA ++ ++ P P + D + +T +
Sbjct: 2867 EEGQVLKVATAEVADAASYMCVAENQAGSAEKLFTLKVQVP--PQISDWTTSQLTATLNS 2924
Query: 1182 FLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKAS 1361
+ L C V + W K G+ + GT L AD+G Y+C+A
Sbjct: 2925 SVSLPCEVYAHPNPEVTWYKDGQPLSLGQEA--FLLPGTHTLRLARAQPADSGTYLCEAL 2982
Query: 1362 NVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDP 1541
N AG D ++ ++I+V A + P
Sbjct: 2983 NAAGRDQKMVQLNVLVPPSFKQAPG-----------GPQEAIQVRAGDKAILSCETDSLP 3031
Query: 1542 IPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
P V W K + + L G RI Q G LEI D+ +D G+Y C N GE
Sbjct: 3032 EPAVTWFKDQ-QPLALGQRIQGLQGGQ--TLEILDSQASDKGVYSCKVSNTAGE 3082
Score = 171 bits (433), Expect = 2e-42
Identities = 168/620 (27%), Positives = 255/620 (41%), Gaps = 11/620 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V+ G++A L CQ+ G ++W + D + P T ++ ++++ L + D G
Sbjct: 541 VTVSPGETAILSCQVLGETPYNLTWVR-DWRALPATTGRISQLSDLS-LEVRSIIPTDGG 598
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y C A N G ++T+L V+E P S R + + G+ V C+ SG +S
Sbjct: 599 QYQCVASNPNGVTRATTWLLVRE---APQVSINARSQRFSQGVEVRVSCSASGYPTPHIS 655
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W ++G L + I +D TL I AG YSC ATN +G+ + L T+
Sbjct: 656 WSREGLALPEDSRIH---VDAQGTLIIQGLAPEDAGNYSCQATNEVGTDEETVTLYYTD- 711
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE-IRSGGNYQISYLENSA 722
PP A V VGE A C +G P +V W + E I + G+ S
Sbjct: 712 --PPSVSAVNAVVLTAVGEEAVLLCAASGVPPPRVIWYRGGLEVILAPGD------SRSG 763
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I + + D G YTC AVNE+G S QL + P T + E G S
Sbjct: 764 TLRIPEAQERDAGLYTCKAVNELGDASAEIQLVVGN---APRLTDPPQDVTVEL-GKSVF 819
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L R G P V W + + + T + ++ +L ++ S+ D Y C+ N
Sbjct: 820 LTCRATGRPPPIVTWRRGDGQALEPGRGSRTGQRDSGVLVFERVSLEDQAPYVCEARNVF 879
Query: 1083 GSALCTSSIVI---------KEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI-RIQ 1232
G A + +V+ + PP + V V EG+ + L+C + P+ +
Sbjct: 880 GKAQAEARLVVTGHGLWVNLEAVGTPPQIANSASVVRVLEGQPVSLTCVILAGRPLPERR 939
Query: 1233 WLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXX 1412
WLKAG + P +R + A+G+ L + DAG Y C A+NVAGS ++
Sbjct: 940 WLKAGSPLPPGNRHAVR-ADGS--LHLDRALQEDAGRYSCVATNVAGSQHRDVEL----- 991
Query: 1413 XXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQG 1592
VV+ A+ G P P + WTK + L
Sbjct: 992 --------------------------VVQGVPASLPCIASGVPTPKITWTK-ETNALTTS 1024
QueryMITS 461
Query: 720 -----AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
++L I D G Y C A N G A++N++ P S + + +
Sbjct: 462 EGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG---PASI--RPMKNITAI 516
Query: 885 EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTC 1064
G + RV G S+ WYKN+ + P + ++ F+NN L D G YTC
Sbjct: 517 AGRDTYIHCRVIGYPYYSIKWYKNS-NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC 575
Query: 1065 KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSC-HVRGSEPIRIQWLK 1241
V L TS V K PP F Q S G+ + + C V G PI I W K
Sbjct: 576 NVL--VQPQLSTSQSVHVTVKVPP-FIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQK 632
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
GR I S + + T+ L +++ G+Y C A N A + +S++
Sbjct: 633 DGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPK- 691
Query: 1422 XXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW--TKG----KWRQL 1583
FV +P+ + G P+P + W +KG +++ +
Sbjct: 692 --------------FVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPI 737
Query: 1584 NQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG 1700
GRI + G L I+ + DSG Y C N G
Sbjct: 738 ALNGRIQVLSNG---SLLIKHVVEEDSGYYLCKVSNDVG 773
Score = 135 bits (341), Expect = 1e-31
Identities = 146/608 (24%), Positives = 243/608 (39%), Gaps = 23/608 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK +VG SL C + GT + +SWY+ L P ++ N+ L+ + + +D G
Sbjct: 323 VKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINH-ENLIMDHMVKSDGG 381
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C ++S+ ++ V + P + + PV C V G+ +++
Sbjct: 382 AYQCFVRKD--KLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTIT 439
Query: 366 WFKDGRPLKDG-----PNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
W D P+ G + TS + V+ LNI + G Y CTA N G AR+
Sbjct: 440 WTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARI 499
Query: 531 ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
+ R P P+ + A+ G C V G + W K N + + Q+++
Sbjct: 500 NV---RGPASIR-PMKNITAIAGRDTYIHCRVIGYPYYSIKWYK-NSNLLPFNHRQVAF- 553
Query: 711 ENSAHLTILKVDKG-DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
EN+ L + V K D G+YTC + + QL+ + + T K+ ++ E
Sbjct: 554 ENNGTLKLSDVQKEVDEGEYTCNVLVQ-------PQLSTSQSV---HVTVKVPPFIQPFE 603
Query: 888 GNSFRLEGR-------VAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGD 1046
F + R V+G PI++ W K+ I + I + L++ S+
Sbjct: 604 FPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMH 663
Query: 1047 AGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIR 1226
G YTC N+A + S ++++ P K V + + G+ + L+C G
Sbjct: 664 NGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGI---YGKAVILNCSAEGYPVPT 720
Query: 1227 IQW-LKAGREIKPSDRCSFS-----FANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSK 1388
I W G + + + +NG+ ++ K V + D+G Y+CK SN G+D SK
Sbjct: 721 IVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLI--KHVVEEDSGYYLCKVSNDVGADVSK 778
Query: 1389 SKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG 1568
S V S P + + G+ V+W K
Sbjct: 779 S--------------MYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKE 824
Query: 1569 KWRQLNQGGRIFIHQK--GDE--AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ R + K G+E + L+I T + DSG + C A N +GE + L V E
Sbjct: 825 DRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQE 884
Query: 1737 RKKQEKIE 1760
+IE
Sbjct: 885 PPDPPEIE 892
Score = 79.0 bits (193), Expect = 2e-14
Identities = 72/297 (24%), Positives = 123/297 (41%), Gaps = 13/297 (4%)
Frame = +3
Query: 9 KVTVGDSASLQCQL-AGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ ++G + C + +G I ++W K + + + + ++L + + +G
Sbjct: : 1593 GRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLR 1772
G + + G L I + D+G Y C A N G + L VN K K+ G
Sbjct: 1025 GHYSVSRNG---TLVIVQPSPQDAGAYVCTATNSVGFSSQEMWLSVN-TKPMIKMNGSQA 1080
Query: 1773 AMLKKTPVLKKGAGEEEEID 1832
+ +K AGEE +D
Sbjct: 1081 VDVPLRVTVK--AGEEVTLD 1098
Score = 162 bits (410), Expect = 9e-40
Identities = 150/580 (25%), Positives = 231/580 (39%), Gaps = 6/580 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G ASL C +G P ++W K L + Y + RN TLV Q D+G Y
Sbjct: 992 VVQGVPASLPCIASGVPTPKITWTKETNALTTSGHYSVS-RNG--TLVIVQPSPQDAGAY 1048
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV----GLPVVFECAVSGSEPIS 359
+C A NSVG S +L+V + + Q DV V G V +C GS
Sbjct: 1049 VCTATNSVGFSSQEMWLSVNTKPMIKMNGSQAVDVPLRVTVKAGEEVTLDCEAQGSPTPL 1108
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W KD PL P L +L + Q G Y CTA+NP G+ S R +
Sbjct: 1109 LTWTKDANPLL--PVTNRYELLPSGSLRLAQAQVGDNGLYGCTASNPAGATS---RRYVL 1163
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
+ PP + + GE+ D C G ++ W KD + G + S
Sbjct: 1164 RVQVPPQVQPGPRVLKVLAGEALDLNCVAEGNPQPQLNWFKDGMALMGEG------AQGS 1217
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF-TKKLSETVEETEGNS 896
H +K D G Y C A N G D+ +L + E PP + T + +E G +
Sbjct: 1218 VHFAAVKT--SDAGLYRCEASNSAGTDTWKLELLVLE---PPHWGTDETKSLLERVAGEN 1272
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
L G+ + W + ++ + L + S+ D+G Y C+ +N
Sbjct: 1273 ASLPCPAQGTPKPRITWRRGPSSEPLNGRPDVAVLDEGSLF-LSSVSLADSGEYECQATN 1331
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQ-HLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
+ GSA + +V+ P P + ++ H+T V+ G+ L L C + G + WLK G+
Sbjct: 1332 EVGSASRRAKLVVYVP--PSIREEGHITNVSGLAGQPLTLECDINGFPAPEVAWLKDGQL 1389
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
+ S + GT + ++ +G Y C+A N AGS +
Sbjct: 1390 VGDSGG-GWDGEGGTF-----GIQESHSGLYSCQAENQAGSAQRDFNLA----------- 1432
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
+ L Q + + T + G P P V+WTK L I + +
Sbjct: 1433 --VFIPPSLLGAGAAQEVLGLAGADVTLECQTSGVPTPQVEWTKDGQPILPGDPHILLQE 1490
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
G L I + D G Y+CVAF+ G+ + L ++
Sbjct: 1491 DGQ--VLRIISSHLGDEGQYQCVAFSPAGQQAKDFQLSIH 1528
Score = 161 bits (408), Expect = 2e-39
Identities = 158/604 (26%), Positives = 245/604 (40%), Gaps = 10/604 (1%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
++ + A L C P ++WY+ L +A + L V + D+G
Sbjct: 2732 EIVENNPAYLYCDTNAIPPPELTWYREGQPL--SAADGVSVLQGGRILQLPLVQAEDAGR 2789
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQL-RDVQETVGLPVVFECAVSGSEPISVS 365
Y C+A N VGE L V + P +++L +V V EC G+ +VS
Sbjct: 2790 YSCKAANEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPALGNPAPAVS 2849
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WF++G P+ P +Q L+ L + + + A Y C A N GSA +L +
Sbjct: 2850 WFQNGLPVSPSPRLQV--LEEGQVLKVATAEVADAASYMCVAENQAGSAE---KLFTLKV 2904
Query: 546 RNPP-FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ PP D + + A + S C V +V W KD + + G Q ++L
Sbjct: 2905 QVPPQISDWTTSQLTATLNSSVSLPCEVYAHPNPEVTWYKDGQPLSLG---QEAFLLPGT 2961
Query: 723 H-LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLS---ETVEETEG 890
H L + + D+G Y C A+N G+D QLN+ L+PPSF + E ++ G
Sbjct: 2962 HTLRLARAQPADSGTYLCEALNAAGRDQKMVQLNV---LVPPSFKQAPGGPQEAIQVRAG 3018
Query: 891 NSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
+ L +V W+K+ + 606 RFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNG 665
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C A N V + L V ++PP F Q RD G V+ C+ G ++
Sbjct: 666 NYTCIARNEAAAVEHQSQLIV---RVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIV 722
Query: 366 W-FKDG------RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
W F G +P+ IQ ++ ++ + D +G Y C +N +G A S
Sbjct: 723 WKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEED---SGYYLCKVSNDVG-ADVSK 778
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSG-GNYQI 701
+ LT P + A G+ + C G +PI V W K++R I Y +
Sbjct: 779 SMYLTVKIPAMITSYPNTTL-ATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLV 837
Query: 702 SYLENSAH----LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKK 860
S E L IL + D+G ++C+A+N G+D QL ++E PP K
Sbjct: 838 STKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIK 894
Database: RefSeq49_HP.fasta
Posted date: Oct 17, 2011 1:42 PM
Number of letters in database: 18,297,164
Number of sequences in database: 32,964
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 32964
Number of Hits to DB: 74,156,423
Number of extensions: 1861615
Number of successful extensions: 15103
Number of sequences better than 1.0e-05: 251
Number of HSP's gapped: 9336
Number of HSP's successfully gapped: 1405
Length of query: 667
Length of database: 18,297,164
Length adjustment: 109
Effective length of query: 558
Effective length of database: 14,704,088
Effective search space: 8204881104
Effective search space used: 8204881104
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)
I L++ + D G+Y+CKV
Sbjct: 3019 DKAILSCETDSLPEPAVTWFKDQQPL--ALGQRIQGLQGGQTLEILDSQASDKGVYSCKV 3076
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFDQ-HLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
SN AG A+ T + I + PP F++ V G L L+C V G + WLK
Sbjct: 3077 SNTAGEAIRTFVLAI---QVPPTFEKPERETVNQVAGRTLVLACDVSGIPAPTVTWLKDR 3133
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
++ S G L+ + A AG Y C A N A ++ K V
Sbjct: 3134 LPVESSVVHGVVSRGGR--LQLSHLQPAQAGTYTCVAEN-AQAEARKDFVV--------- 3181
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQLNQGGRIF 1604
V ++ Q V+EK + G P P++ W K G + G +
Sbjct: 3182 ---SVLVPPQIQDSGMAQEHNVLEKQEIRLHCEAEGQPPPDITWLKDGGLLDQHVGPHLR 3238
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIE--SNVNLQVNERKKQEKIEGDLRAM 1778
+ G + L ++ DSG Y CVA N GE VN+ V KQ+ GD +
Sbjct: 3239 FYLDG--STLVLKGLRTADSGAYTCVAHNPAGEDARLHTVNVLVPPTIKQQ--AGDTGTL 3294
Query: 1779 LKKT 1790
+ +T
Sbjct: 3295 VSRT 3298
Score = 158 bits (400), Expect = 1e-38
Identities = 149/583 (25%), Positives = 233/583 (39%), Gaps = 17/583 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + +L C G P V+W + + ++ +N+ +L + ++ +G
Sbjct: 2239 VSVIQDGNTTLACNATGKPLPVVTWQRDGQPVSVEPGLRLQNQNH--SLHVERAQASHAG 2296
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C AEN+ G L+V S L +V T+ C +G +V
Sbjct: 2297 GYSCVAENTAGRAERRFALSVLAPPHLTGDSDSLTNVTATLHGSFTLLCEAAGVPAPTVQ 2356
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WF++G+P+ P T L L + Q G YSC A+N G A R E
Sbjct: 2357 WFQEGQPI--SPREGTYLLAGGWMLKMTQAQEQDRGLYSCLASNEAGEA---RRNFSVEV 2411
Query: 546 RNPPFFDIPLAPVDAVV----GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
PP I ++ V+ G++A EC+ TG P KV W KD + + Y++S
Sbjct: 2412 LVPP--SIENEDLEEVIKVPEGQTAQLECNATGHPPPKVTWFKDGQSLTVEDPYEMS--P 2467
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF----TKKLSETVEE 881
+ A L I + + + G Y+C A N VG+ + QL++ L+ P+ K +E V
Sbjct: 2468 DGAFLWIPQANLSNAGHYSCIASNAVGEKTKHTQLSV---LVVPTILGVPEKNANEEVTV 2524
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
T N L ++ W K+ + N ++ + LQ+ A DAG YT
Sbjct: 2525 TINNPISLICEALAFPSPNITWMKDGSPFEASKNIQLLPGTHG--LQILNAQKEDAGQYT 2582
Query: 1062 CKVSNDAGSALCTSSIVIKEP----KKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRI 1229
C V+N+ G A + + P K P+ + + V L L C + P I
Sbjct: 2583 CVVTNELGEATKNYHVEVLIPPSISKDDPLGEVSVKEVKTKVNSSLTLECECWATPPPSI 2642
Query: 1230 QWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXX 1409
W K GR + PS R S +L+ + +D+G Y+C A+NVAG D V
Sbjct: 2643 SWYKDGRPVTPSHR--LSVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQV 2700
Query: 1410 XXXXXXXXXXXXVDGKLFFVSEPQS-----IRVVEKTTATFIAKVGGDPIPNVKWTKGKW 1574
L E Q +VE A P P + W + +
Sbjct: 2701 PPMFQKMGDVDAGFEPLPHEEEAQGRVTEYREIVENNPAYLYCDTNAIPPPELTWYR-EG 2759
Query: 1575 RQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
+ L+ + + Q G +L + D+G Y C A N+ GE
Sbjct: 2760 QPLSAADGVSVLQGGRILQLPL--VQAEDAGRYSCKAANEVGE 2800
Score = 156 bits (395), Expect = 5e-38
Identities = 153/579 (26%), Positives = 229/579 (39%), Gaps = 12/579 (2%)
Frame = +3
Query: 36 LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSV 215
L C+ G P ++W K L + F + +TLV + + DSG Y C A N
Sbjct: 3208 LHCEAEGQPPPDITWLKDGGLLDQHVGPHLRFYLDGSTLVLKGLRTADSGAYTCVAHNPA 3267
Query: 216 GEVSSSTFLTVQEQKLPPSFSRQLRDVQETV---GLPVVFECAVSGSEPISVSWFKDGRP 386
GE + + V +PP+ +Q D V G V C V GS PI VSW KDG P
Sbjct: 3268 GEDARLHTVNV---LVPPTIKQQAGDTGTLVSRTGELVTMVCPVQGSPPIHVSWLKDGLP 3324
Query: 387 LKDGPNIQTSFLDNVA-TLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFF 563
L P Q + L + TL I Q + +G ++C A +P G A + L++ PP
Sbjct: 3325 L---PLSQRTLLHSSGRTLRISQVQLADSGVFTCVAASPAGVADRNFTLLVLV---PPI- 3377
Query: 564 DIPLAPVD------AVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
L PV+ A G C G+ V+W KD + LE
Sbjct: 3378 ---LEPVEFQNNVMAAQGSEVVLPCEARGSPLPLVSWMKDGEPLLP------QSLEQGPG 3428
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE--ETEGNSF 899
L + V GD G Y+C A +E G+ QL + + P ++ ET E T G
Sbjct: 3429 LKLESVSVGDAGTYSCTAASEAGEARRHFQLTVMD----PPHIEESGETSELSLTPGAHL 3484
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L G P ++ W+K+ + T N +L+V+ + +AGLYTC +
Sbjct: 3485 ELLCEARGIPPPNITWHKDGQALRRTEN----DSQAGRVLRVRDVQVDNAGLYTCLAESP 3540
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AG + + ++ P + V ++ G+ + L C V I+W + G ++
Sbjct: 3541 AGEVEKSFRVRVQAPPNVVGPRGPRSVVGLAPGQLI-LECSVEAEPAPEIEWHRGGVLLQ 3599
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
F L+ + ++ AD GDY C A N AGS + +V
Sbjct: 3600 AD--AHTHFPEQGRFLKLQALSTADGGDYSCTARNRAGSTSVAFRV-------------- 3643
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
+ S P ++ V T + G P P V W K R+ +G
Sbjct: 3644 -EIHTAPTIQSGPNTVNVSVNRTTLLPCQTHGVPTPLVSWRKDGIPLHPGSPRLEFLPEG 3702
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
L I D+G Y C+A N G ++L+V E
Sbjct: 3703 ---SLRIHPVLAQDAGHYLCLASNSAGSDRKGLDLRVFE 3738
Score = 156 bits (394), Expect = 6e-38
Identities = 151/589 (25%), Positives = 234/589 (39%), Gaps = 13/589 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G +A L C+ G P ++WYK T L P++ ++ + L + +D+G
Sbjct: 1542 VTVLEGHTAQLLCEARGMPSPAITWYKDGTLLAPSS--EVVYSKGGRQLQLVKAQPSDAG 1599
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRD---VQETVGLPVVFECAVSGSEPI 356
Y C+A N G ST L V +PP+ VQ G PV EC G P
Sbjct: 1600 LYTCQASNPAGITKKSTSLEVY---VPPTIEGADGGPYLVQAVAGRPVALECVARGHPPP 1656
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSA-------- 512
++SW +G P+ D ++L+ L + + G YSC A++P G A
Sbjct: 1657 TISWQHEGLPVVDS---NGTWLEAGGALQLENPGEASGGLYSCVASSPAGEAVLQYSVEM 1713
Query: 513 SSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
+L++ EG + V A VG+S D C +G+ + W ++ R
Sbjct: 1714 QVPPQLLVAEG---------MGQVTATVGQSLDLPCQASGSPVPTIQWLQNGRPAEELAG 1764
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET 872
Q++ H++ V+ +G + C A NE G ++++ E PS E
Sbjct: 1765 VQLASQGTILHIS--HVELNHSGLFACQATNEAGTAGAEVEVSVHEL---PSVHIIGGEN 1819
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAG 1052
+ L+ G S+ W+K+ V + + LQ++KA + D G
Sbjct: 1820 LTAPFLQPVTLQCVGIGVPTPSLRWWKDGVAVATSGG----------NLQIEKADLRDEG 1869
Query: 1053 LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQ 1232
+YTC +N AG + V + PP + V E + L C G P +
Sbjct: 1870 VYTCSATNLAGE---SKKDVTLKVLVPPNIEPGPVNKVVLENASVTLECLASGVPPPDVS 1926
Query: 1233 WLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSK--SKVTXX 1406
W K + I R S A+G VL + V +DAG Y C A+NVAGS K +V
Sbjct: 1927 WFKGRQPISTQRRVIVS-ADG-RVLHIERVQLSDAGSYRCVATNVAGSAGLKYGLRVNVP 1984
Query: 1407 XXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLN 1586
+ G F + + T I G+P+ Q+
Sbjct: 1985 PRITLPPNLPGPVLLGTPFRL----TCNATGTPRPTLIWLKDGNPVAVFNADLPLGLQVF 2040
Query: 1587 QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
GG++ L + +DSG Y CVA + GE +V LQV+
Sbjct: 2041 PGGQV----------LTVASARASDSGSYSCVAVSAVGEDRRDVILQVH 2079
Score = 151 bits (382), Expect = 2e-36
Identities = 124/462 (26%), Positives = 200/462 (43%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+V + L C+ +G P+ V W K + A ++ + + D+G
Sbjct: 3933 VQVVASEEVLLPCEASGIPQPMVIWQKEGLSIPEGAHMQVLPSGQLRIM---HASPEDAG 3989
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C A+NSVG + T L VQ +PP L D+ G + C GS +++
Sbjct: 3990 NYFCIAQNSVGSAMAKTRLVVQ---VPPVIENGLPDLSTIEGSHALLPCTAKGSPEPAIT 4046
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W KDG + T L L + ++ AG Y CTA N +G A R+ LT
Sbjct: 4047 WEKDGHLVSGAEGKFT--LQPSGELLVKNSEGQDAGTYICTAENAVGRARR--RVHLTIL 4102
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P +P +G+ C G+ ++ W +++ + G +S + +
Sbjct: 4103 TLPVLTTLP-GDRSLRLGDRLWLRCVARGSPTPRIGWTINDQPVTEG----VSEQDGGST 4157
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L V + D+G YTC+A N VG+ + +++KE P + + E G S +L
Sbjct: 4158 LQRAAVTREDSGTYTCWAENRVGRVQAVSFVHVKEA---PVLQGEAFSYLVEPVGGSIQL 4214
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
V G + W K+ + + P + +N +L + + M DAG Y C N+ G
Sbjct: 4215 HCVVRGDPAPDIHWTKDGLPL-PISRLHFQLQNGSLT--ILRTKMDDAGRYQCLAVNEMG 4271
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
+ ++V++ PVF VTV G ++L C G I+WL+AGR ++ +
Sbjct: 4272 TVKKVVTVVLQSA---PVFQVEPQDVTVRSGVDVELRCRATGEPVPTIEWLRAGRPLQ-A 4327
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS 1391
R + +G+ LE V DAG Y C A N GS T+K+
Sbjct: 4328 GRKLRALPDGSLWLE--HVEAGDAGVYECVAHNHLGSVTAKA 4367
Score = 145 bits (367), Expect = 9e-35
Identities = 147/565 (26%), Positives = 213/565 (37%)
Frame = +3
Query: 36 LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSV 215
L C G+P VSW K T+L + + L + +G Y C A NS
Sbjct: 3852 LTCHSTGSPTPAVSWSKAGTQLGARGSGYRILPSGA--LEIERALPLHAGRYTCTARNSA 3909
Query: 216 GEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKD 395
G LTVQ P VQ V+ C SG V W K+G + +
Sbjct: 3910 GVARKHMVLTVQAS---PVVKPLPSVVQVVASEEVLLPCEASGIPQPMVIWQKEGLSIPE 3966
Query: 396 GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPL 575
G ++Q L I AG Y C A N +GSA + RL++ + PP + L
Sbjct: 3967 GAHMQVL---PSGQLRIMHASPEDAGNYFCIAQNSVGSAMAKTRLVV---QVPPVIENGL 4020
Query: 576 APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGD 755
+ + G A C G+ + W KD + SG + + L+ S L + + D
Sbjct: 4021 PDLSTIEGSHALLPCTAKGSPEPAITWEKDGHLV-SGAEGKFT-LQPSGELLVKNSEGQD 4078
Query: 756 TGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPI 935
G Y C A N VG+ L I L P T + G+ L GS
Sbjct: 4079 AGTYICTAENAVGRARRRVHLTI---LTLPVLTTLPGDRSLRL-GDRLWLRCVARGSPTP 4134
Query: 936 SVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVI 1115
+ W N+ + ++ ++ LQ + D+G YTC N G S + +
Sbjct: 4135 RIGWTINDQPVTEG----VSEQDGGSTLQRAAVTREDSGTYTCWAENRVGRVQAVSFVHV 4190
Query: 1116 KEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANG 1295
KE P + + + + G +QL C VRG I W K G + P R F NG
Sbjct: 4191 KEA--PVLQGEAFSYLVEPVGGSIQLHCVVRGDPAPDIHWTKDGLPL-PISRLHFQLQNG 4247
Query: 1296 TAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSE 1475
+ L DAG Y C A N G T K VT + F E
Sbjct: 4248 S--LTILRTKMDDAGRYQCLAVNEMG--TVKKVVTVV-------------LQSAPVFQVE 4290
Query: 1476 PQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTK 1655
PQ + V + G+P+P ++W + R L G ++ + + L +
Sbjct: 4291 PQDVTVRSGVDVELRCRATGEPVPTIEWLRA-GRPLQAGRKL---RALPDGSLWLEHVEA 4346
Query: 1656 TDSGLYRCVAFNKHGEIESNVNLQV 1730
D+G+Y CVA N G + + L V
Sbjct: 4347 GDAGVYECVAHNHLGSVTAKALLAV 4371
Score = 139 bits (349), Expect = 1e-32
Identities = 145/585 (24%), Positives = 239/585 (40%), Gaps = 8/585 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V+V + L CQ G P VSW K L P + ++ F +L + V + D+G
Sbjct: 3658 VNVSVNRTTLLPCQTHGVPTPLVSWRKDGIPLHPGSP-RLEFLPE-GSLRIHPVLAQDAG 3715
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y+C A NS G L V E PP+ + ++ T P C GS V+
Sbjct: 3716 HYLCLASNSAGSDRKGLDLRVFE---PPAIAPGPSNLTLTAYSPASLPCEARGSPKPLVT 3772
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRS--FAGQYSCTATNPIGSASSSARLIL- 536
W+KDG+ L +Q + + +F T S + Q+ C +N +G + ++ +
Sbjct: 3773 WWKDGQKLD--LRLQQGAYRLLPSNALFLTAPSPQDSAQFECVVSNEVGESRRRYQVTVH 3830
Query: 537 ---TEGRNPPFFDIP-LAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRS-GGNYQI 701
T + F + +APV CH TG+ V+W+K ++ + G Y+I
Sbjct: 3831 VPPTIADDQTHFTVTRMAPVILT--------CHSTGSPTPAVSWSKAGTQLGARGSGYRI 3882
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
S L I + G+YTC A N G L ++ + K L V+
Sbjct: 3883 L---PSGALEIERALPLHAGRYTCTARNSAGVARKHMVLTVQASPV----VKPLPSVVQV 3935
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
L +G V W K + I A+ ++ L++ AS DAG Y
Sbjct: 3936 VASEEVLLPCEASGIPQPMVIWQKEGLSIPEGAHMQVLPSGQ---LRIMHASPEDAGNYF 3992
Query: 1062 CKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLK 1241
C N GSA+ + +V++ P PV + L ++ EG L C +GS I W K
Sbjct: 3993 CIAQNSVGSAMAKTRLVVQVP---PVIENGLPDLSTIEGSHALLPCTAKGSPEPAITWEK 4049
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
G + ++ +G ++ K+ DAG Y+C A N G + +T
Sbjct: 4050 DGHLVSGAEGKFTLQPSGELLV--KNSEGQDAGTYICTAENAVGRARRRVHLTILTLPV- 4106
Query: 1422 XXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRI 1601
L + +S+R+ ++ +A+ G P P + WT + + +G
Sbjct: 4107 ------------LTTLPGDRSLRLGDRLWLRCVAR--GSPTPRIGWTIND-QPVTEG--- 4148
Query: 1602 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ ++ + L+ T+ DSG Y C A N+ G +++ + V E
Sbjct: 4149 -VSEQDGGSTLQRAAVTREDSGTYTCWAENRVGRVQAVSFVHVKE 4192
Score = 138 bits (348), Expect = 1e-32
Identities = 139/564 (24%), Positives = 219/564 (38%), Gaps = 5/564 (0%)
Frame = +3
Query: 150 LVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFE 329
L Q S G Y C N+ G S L V L V
Sbjct: 2191 LYLGQAQSAQEGTYTCECSNAAGTSSQEQSLEVLVPPQVTGLWEPLTTVSVIQDGNTTLA 2250
Query: 330 CAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGS 509
C +G V+W +DG+P+ P ++ ++ +L++ + S AG YSC A N G
Sbjct: 2251 CNATGKPLPVVTWQRDGQPVSVEPGLRLQNQNH--SLHVERAQASHAGGYSCVAENTAGR 2308
Query: 510 ASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSG- 686
A L + + L V A + S C G V W ++ + I
Sbjct: 2309 AERRFALSVLAPPHLTGDSDSLTNVTATLHGSFTLLCEAAGVPAPTVQWFQEGQPISPRE 2368
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIK-ERLIPPSFTKK- 860
G Y L L + + + D G Y+C A NE G+ A+ N E L+PPS +
Sbjct: 2369 GTY---LLAGGWMLKMTQAQEQDRGLYSCLASNEAGE----ARRNFSVEVLVPPSIENED 2421
Query: 861 LSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASM 1040
L E ++ EG + +LE G P V W+K+ + T + L + +A++
Sbjct: 2422 LEEVIKVPEGQTAQLECNATGHPPPKVTWFKDGQSL--TVEDPYEMSPDGAFLWIPQANL 2479
Query: 1041 GDAGLYTCKVSNDAGSALCTSSI-VIKEPKKPPVFDQHLTP-VTVSEGEFLQLSCHVRGS 1214
+AG Y+C SN G + + V+ P V +++ VTV+ + L C
Sbjct: 2480 SNAGHYSCIASNAVGEKTKHTQLSVLVVPTILGVPEKNANEEVTVTINNPISLICEALAF 2539
Query: 1215 EPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSK 1394
I W+K G + S + GT L+ + K DAG Y C +N G T
Sbjct: 2540 PSPNITWMKDGSPFEASK--NIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEATKNYH 2597
Query: 1395 VTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKW 1574
V V K ++ ++ T + P P++ W K
Sbjct: 2598 VEVLIPPSISKDDPLGEVSVK--------EVKTKVNSSLTLECECWATPPPSISWYKDG- 2648
Query: 1575 RQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEK 1754
R + R+ + G+ L+I+ T +DSG Y CVA N GE + + N+ + +K
Sbjct: 2649 RPVTPSHRLSV--LGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQK 2706
Query: 1755 IEGDLRAMLKKTPVLKKGAGEEEE 1826
+ GD+ A + P ++ G E
Sbjct: 2707 M-GDVDAGFEPLPHEEEAQGRVTE 2729
Score = 137 bits (344), Expect = 4e-32
Identities = 136/577 (23%), Positives = 225/577 (38%), Gaps = 6/577 (1%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G +L+CQ +G P V W K + P + + + + + D G+Y C
Sbjct: 1453 GADVTLECQTSGVPTPQVEWTKDGQPILPGDPHILLQEDGQVLRIISS-HLGDEGQYQCV 1511
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPISVSWFK 374
A + G+ + L++ PP+ S + +V G C G +++W+K
Sbjct: 1512 AFSPAGQQAKDFQLSIHS---PPTIWGSNETGEVTVLEGHTAQLLCEARGMPSPAITWYK 1568
Query: 375 DGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNP 554
DG L P+ + + L + + S AG Y+C A+NP G S L +
Sbjct: 1569 DGTLL--APSSEVVYSKGGRQLQLVKAQPSDAGLYTCQASNPAGITKKSTSLEVYVPPTI 1626
Query: 555 PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTI 734
D V AV G EC G P ++W + + ++LE L +
Sbjct: 1627 EGADGGPYLVQAVAGRPVALECVARGHPPPTISWQHEGLPVVDSNG---TWLEAGGALQL 1683
Query: 735 LKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGR 914
+ G Y+C A + G+ Q +++ ++ P + V T G S L +
Sbjct: 1684 ENPGEASGGLYSCVASSPAGE--AVLQYSVEMQVPPQLLVAEGMGQVTATVGQSLDLPCQ 1741
Query: 915 VAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSAL 1094
+GS ++ W +N A ++ + +L + + +GL+ C+ +N+AG+A
Sbjct: 1742 ASGSPVPTIQWLQNGRPAEELAGVQLA--SQGTILHISHVELNHSGLFACQATNEAGTAG 1799
Query: 1095 CTSSIVIKE-PKKPPVFDQHLTPVTVSEGEFLQ---LSCHVRGSEPIRIQWLKAGREIKP 1262
+ + E P + ++LT FLQ L C G ++W K G +
Sbjct: 1800 AEVEVSVHELPSVHIIGGENLT------APFLQPVTLQCVGIGVPTPSLRWWKDGVAVAT 1853
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S G +E D+ D G Y C A+N+AG SK VT
Sbjct: 1854 S--------GGNLQIEKADLR--DEGVYTCSATNLAGE--SKKDVTLKVLVPPNIEPG-- 1899
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
P + V+E + T G P P+V W KG+ + ++ R+ + D
Sbjct: 1900 -----------PVNKVVLENASVTLECLASGVPPPDVSWFKGR-QPISTQRRVIV--SAD 1945
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
L I +D+G YRCVA N G L+VN
Sbjct: 1946 GRVLHIERVQLSDAGSYRCVATNVAGSAGLKYGLRVN 1982
Score = 136 bits (343), Expect = 5e-32
Identities = 143/608 (23%), Positives = 239/608 (39%), Gaps = 10/608 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V G + L C ++G P V+W K + + + + R L + + +G
Sbjct: 3105 VNQVAGRTLVLACDVSGIPAPTVTWLKDRLPVESSVVHGVVSRG--GRLQLSHLQPAQAG 3162
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C AEN+ E ++V +PP S ++ + C G P
Sbjct: 3163 TYTCVAENAQAEARKDFVVSV---LVPPQIQDSGMAQEHNVLEKQEIRLHCEAEGQPPPD 3219
Query: 360 VSWFKDGRPLKD--GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
++W KDG L GP+++ +LD +TL + + +G Y+C A NP G ARL
Sbjct: 3220 ITWLKDGGLLDQHVGPHLR-FYLDG-STLVLKGLRTADSGAYTCVAHNPAG---EDARLH 3274
Query: 534 LTEGRNPPFFDIPLAPVDAVV---GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
PP +V GE C V G+ PI V+W KD + Q +
Sbjct: 3275 TVNVLVPPTIKQQAGDTGTLVSRTGELVTMVCPVQGSPPIHVSWLKDGLPLPLS---QRT 3331
Query: 705 YLENSAH-LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK-KLSETVE 878
L +S L I +V D+G +TC A + G L + L+PP + V
Sbjct: 3332 LLHSSGRTLRISQVQLADSGVFTCVAASPAGVADRNFTLLV---LVPPILEPVEFQNNVM 3388
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
+G+ L GS V+W K+ + P + L+++ S+GDAG Y
Sbjct: 3389 AAQGSEVVLPCEARGSPLPLVSWMKDGEPLLPQS------LEQGPGLKLESVSVGDAGTY 3442
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFDQ-HLTPVTVSEGEFLQLSCHVRGSEPIRIQW 1235
+C +++AG A + + +P P + + + ++++ G L+L C RG P I W
Sbjct: 3443 SCTAASEAGEARRHFQLTVMDP--PHIEESGETSELSLTPGAHLELLCEARGIPPPNITW 3500
Query: 1236 LKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXX 1415
K G+ ++ ++ S VL +DV +AG Y C A + AG +V
Sbjct: 3501 HKDGQALRRTENDS----QAGRVLRVRDVQVDNAGLYTCLAESPAGEVEKSFRVRVQAPP 3556
Query: 1416 XXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGG 1595
P+S+ + V +P P ++W +G L
Sbjct: 3557 NVVGPRG-------------PRSVVGLAPGQLILECSVEAEPAPEIEWHRG-GVLLQADA 3602
Query: 1596 RIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRA 1775
++G KL+ T D G Y C A N+ G ++++ + +
Sbjct: 3603 HTHFPEQGRFLKLQALST--ADGGDYSCTARNRAGSTSVAFRVEIHTAPTIQSGPNTVNV 3660
Query: 1776 MLKKTPVL 1799
+ +T +L
Sbjct: 3661 SVNRTTLL 3668
Score = 136 bits (342), Expect = 7e-32
Identities = 142/585 (24%), Positives = 223/585 (38%), Gaps = 10/585 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ G +L+C G P +SW P + L G
Sbjct: 1636 VQAVAGRPVALECVARGHPPPTISWQHEGL---PVVDSNGTWLEAGGALQLENPGEASGG 1692
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C A + GE + E ++PP + + V TVG + C SGS +
Sbjct: 1693 LYSCVASSPAGEAVLQYSV---EMQVPPQLLVAEGMGQVTATVGQSLDLPCQASGSPVPT 1749
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
+ W ++GRP ++ +Q + + L+I + + +G ++C ATN G+A + + +
Sbjct: 1750 IQWLQNGRPAEELAGVQLASQGTI--LHISHVELNHSGLFACQATNEAGTAGAEVEVSVH 1807
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIR-SGGNYQISYLEN 716
E P I + A + +C G + W KD + SGGN QI
Sbjct: 1808 E--LPSVHIIGGENLTAPFLQPVTLQCVGIGVPTPSLRWWKDGVAVATSGGNLQIE---- 1861
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
K D D G YTC A N G+ L + L+PP+ V E S
Sbjct: 1862 -------KADLRDEGVYTCSATNLAGESKKDVTLKV---LVPPNIEPGPVNKVV-LENAS 1910
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
LE +G P V+W+K I + + + +L +++ + DAG Y C +N
Sbjct: 1911 VTLECLASGVPPPDVSWFKGRQPI--STQRRVIVSADGRVLHIERVQLSDAGSYRCVATN 1968
Query: 1077 DAGSALCTSSIVIKEPKK---PPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
AGSA + + P + PP P V G +L+C+ G+ + WLK G
Sbjct: 1969 VAGSAGLKYGLRVNVPPRITLPPNL-----PGPVLLGTPFRLTCNATGTPRPTLIWLKDG 2023
Query: 1248 REIKPSDR---CSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXX 1418
+ + G VL +D+G Y C A + G D
Sbjct: 2024 NPVAVFNADLPLGLQVFPGGQVLTVASARASDSGSYSCVAVSAVGEDRRD---------- 2073
Query: 1419 XXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQLNQGG 1595
V + E ++ VV + T + P P ++W K G+ + + G
Sbjct: 2074 -----VILQVHMPPSILGEELNMSVVVNESVTLECQSHAVPPPVLRWQKDGRPLEPHPGI 2128
Query: 1596 RIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
R+ D+A LE+ D+G Y C A N+ G E + NL V
Sbjct: 2129 RL----SADKALLEVDRAAVWDAGHYTCEAINQAGRSEKHFNLHV 2169
Score = 134 bits (336), Expect = 3e-31
Identities = 131/524 (25%), Positives = 208/524 (39%), Gaps = 6/524 (1%)
Frame = +3
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
+ G Y C A + G +S + + + PP +V + G + C V G P
Sbjct: 505 EEGTYQCIAVSRAGSGRASAQIVITD---PPPQLVPGPNVTVSPGETAILSCQVLGETPY 561
Query: 357 SVSWFKDGR--PLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
+++W +D R P G Q S L ++ +I TD GQY C A+NP G ++ L
Sbjct: 562 NLTWVRDWRALPATTGRISQLSDL-SLEVRSIIPTD---GGQYQCVASNPNGVTRATTWL 617
Query: 531 ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
++ E P I G C +G ++W+++ + +
Sbjct: 618 LVREA---PQVSINARSQRFSQGVEVRVSCSASGYPTPHISWSREGLALPEDSRIHV--- 671
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEG 890
+ L I + D G Y+C A NEVG D T L + PPS + ++ V G
Sbjct: 672 DAQGTLIIQGLAPEDAGNYSCQATNEVGTDEETVTLYYTD---PPSVSA-VNAVVLTAVG 727
Query: 891 NSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
L +G P V WY+ +E+ + + L++ +A DAGLYTCK
Sbjct: 728 EEAVLLCAASGVPPPRVIWYRGGLEVILAPG-----DSRSGTLRIPEAQERDAGLYTCKA 782
Query: 1071 SNDAGSALCTSSIVIKEPKK---PPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLK 1241
N+ G A +V+ + PP VTV G+ + L+C G P + W +
Sbjct: 783 VNELGDASAEIQLVVGNAPRLTDPP------QDVTVELGKSVFLTCRATGRPPPIVTWRR 836
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
+ R S + + VL F+ V+ D YVC+A NV G +++++
Sbjct: 837 GDGQALEPGRGSRTGQRDSGVLVFERVSLEDQAPYVCEARNVFGKAQAEARLV---VTGH 893
Query: 1422 XXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKV-GGDPIPNVKWTKGKWRQLNQGGR 1598
V + +RV+E + + G P+P +W K L G R
Sbjct: 894 GLWVNLEAVGTPPQIANSASVVRVLEGQPVSLTCVILAGRPLPERRWLKA-GSPLPPGNR 952
Query: 1599 IFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
H + L + + D+G Y CVA N G +V L V
Sbjct: 953 ---HAVRADGSLHLDRALQEDAGRYSCVATNVAGSQHRDVELVV 993
Score = 132 bits (331), Expect = 1e-30
Identities = 149/581 (25%), Positives = 219/581 (37%), Gaps = 6/581 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ +T G L C+ G P ++W+K LR T R L V +++G
Sbjct: 3476 LSLTPGAHLELLCEARGIPPPNITWHKDGQALRRTENDSQAGR----VLRVRDVQVDNAG 3531
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLP---VVFECAVSGSEPI 356
Y C AE+ GEV S + VQ PP+ R + VGL ++ EC+V
Sbjct: 3532 LYTCLAESPAGEVEKSFRVRVQA---PPNVVGP-RGPRSVVGLAPGQLILECSVEAEPAP 3587
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
+ W + G L+ + T F + L + + G YSCTA N GS S + R+
Sbjct: 3588 EIEWHRGGVLLQ--ADAHTHFPEQGRFLKLQALSTADGGDYSCTARNRAGSTSVAFRV-- 3643
Query: 537 TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
E P V+ V + C G V+W KD + G ++ +L
Sbjct: 3644 -EIHTAPTIQSGPNTVNVSVNRTTLLPCQTHGVPTPLVSWRKDGIPLHPGSP-RLEFLPE 3701
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE-TVEETEGN 893
+ L I V D G Y C A N G D L + E PP+ S T+
Sbjct: 3702 GS-LRIHPVLAQDAGHYLCLASNSAGSDRKGLDLRVFE---PPAIAPGPSNLTLTAYSPA 3757
Query: 894 SFRLEGRVAGSQPISVAWYKNN--VEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
S E R GS V W+K+ +++ +NAL L S D+ + C
Sbjct: 3758 SLPCEAR--GSPKPLVTWWKDGQKLDLRLQQGAYRLLPSNALFLTAP--SPQDSAQFECV 3813
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
VSN+ G + + + P P T TV+ + L+CH GS + W KAG
Sbjct: 3814 VSNEVGESRRRYQVTVHVP---PTIADDQTHFTVTRMAPVILTCHSTGSPTPAVSWSKAG 3870
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
++ R S + LE + AG Y C A N AG +T
Sbjct: 3871 TQL--GARGSGYRILPSGALEIERALPLHAGRYTCTARNSAGVARKHMVLT--------- 3919
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
V P ++VV + G P P V W K + + +G + +
Sbjct: 3920 ------VQASPVVKPLPSVVQVVASEEVLLPCEASGIPQPMVIWQK-EGLSIPEGAHMQV 3972
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
G +L I + D+G Y C+A N G + L V
Sbjct: 3973 LPSG---QLRIMHASPEDAGNYFCIAQNSVGSAMAKTRLVV 4010
Score = 131 bits (329), Expect = 2e-30
Identities = 147/589 (24%), Positives = 223/589 (37%), Gaps = 18/589 (3%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G+ ++ C + G+P I VSW K L + +H ++ TL +QV DSG + C
Sbjct: 3299 GELVTMVCPVQGSPPIHVSWLKDGLPLPLSQRTLLH--SSGRTLRISQVQLADSGVFTCV 3356
Query: 201 AENSVGEVSSSTFLTVQEQKL--PPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFK 374
A + G + L V + P F + Q G VV C GS VSW K
Sbjct: 3357 AASPAGVADRNFTLLVLVPPILEPVEFQNNVMAAQ---GSEVVLPCEARGSPLPLVSWMK 3413
Query: 375 DGRP-----LKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
DG P L+ GP ++ L++V+ AG YSCTA + G A +L +
Sbjct: 3414 DGEPLLPQSLEQGPGLK---LESVSV--------GDAGTYSCTAASEAGEARRHFQLTVM 3462
Query: 540 EGRNPPFFDI--PLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
+ PP + + + G + C G P + W KD + +R N +
Sbjct: 3463 D---PPHIEESGETSELSLTPGAHLELLCEARGIPPPNITWHKDGQALRRTENDS----Q 3515
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKLSETVEETEG 890
L + V + G YTC A + G+ + ++ ++ PP+ + +V
Sbjct: 3516 AGRVLRVRDVQVDNAGLYTCLAESPAGEVEKSFRVRVQ---APPNVVGPRGPRSVVGLAP 3572
Query: 891 NSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
LE V + W++ V + A+ F L+++ S D G Y+C
Sbjct: 3573 GQLILECSVEAEPAPEIEWHRGGVLLQ--ADAHTHFPEQGRFLKLQALSTADGGDYSCTA 3630
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
N AGS TS E P V VS L C G + W K G
Sbjct: 3631 RNRAGS---TSVAFRVEIHTAPTIQSGPNTVNVSVNRTTLLPCQTHGVPTPLVSWRKDGI 3687
Query: 1251 EIKP-SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
+ P S R F G+ L V DAG Y+C ASN AGSD
Sbjct: 3688 PLHPGSPRLEF-LPEGS--LRIHPVLAQDAGHYLCLASNSAGSDRK-------------- 3730
Query: 1428 XXXXXXVDGKLF----FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWR---QLN 1586
+D ++F P ++ + + A+ + G P P V W K + +L
Sbjct: 3731 -----GLDLRVFEPPAIAPGPSNLTLTAYSPASLPCEARGSPKPLVTWWKDGQKLDLRLQ 3785
Query: 1587 QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
QG + L + + DS + CV N+ GE + V+
Sbjct: 3786 QGAYRLLPSNA----LFLTAPSPQDSAQFECVVSNEVGESRRRYQVTVH 3830
Score = 125 bits (313), Expect = 2e-28
Identities = 152/646 (23%), Positives = 231/646 (35%), Gaps = 70/646 (10%)
Frame = +3
Query: 3 PVKVTVGDSAS--LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRN-NVATLVFNQVDS 173
PV V ++AS L+C +G P VSW+KG +P +T + + + L +V
Sbjct: 1900 PVNKVVLENASVTLECLASGVPPPDVSWFKGR---QPISTQRRVIVSADGRVLHIERVQL 1956
Query: 174 NDSGEYICRAENSVGEVSSSTFLTVQEQK---LPPSFSRQLRDVQETVGLPVVFECAVSG 344
+D+G Y C A N G L V LPP+ + +G P C +G
Sbjct: 1957 SDAGSYRCVATNVAGSAGLKYGLRVNVPPRITLPPNLPGPV-----LLGTPFRLTCNATG 2011
Query: 345 SEPISVSWFKDGRPLK----DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSA 512
+ ++ W KDG P+ D P + L + S +G YSC A + +G
Sbjct: 2012 TPRPTLIWLKDGNPVAVFNADLP-LGLQVFPGGQVLTVASARASDSGSYSCVAVSAVGE- 2069
Query: 513 SSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
R ++ + PP + VV ES EC P + W KD R +
Sbjct: 2070 --DRRDVILQVHMPPSILGEELNMSVVVNESVTLECQSHAVPPPVLRWQKDGRPLEPHPG 2127
Query: 693 YQISYLENSAHLTILKVDKG---DTGQYTCYAVNEVGKD--------------------- 800
++S A +L+VD+ D G YTC A+N+ G+
Sbjct: 2128 IRLS-----ADKALLEVDRAAVWDAGHYTCEAINQAGRSEKHFNLHVWGQPLPGEGDSLE 2182
Query: 801 ------------------------------SCTAQLNIKERLIPPSFTK--KLSETVEET 884
++Q E L+PP T + TV
Sbjct: 2183 QVLAVGRLLYLGQAQSAQEGTYTCECSNAAGTSSQEQSLEVLVPPQVTGLWEPLTTVSVI 2242
Query: 885 EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTC 1064
+ + L G V W ++ + + +N++ L V++A AG Y+C
Sbjct: 2243 QDGNTTLACNATGKPLPVVTWQRDGQPVSVEPGLRLQNQNHS--LHVERAQASHAGGYSC 2300
Query: 1065 KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKA 1244
N AG A ++ + P LT VT + L C G +QW +
Sbjct: 2301 VAENTAGRAERRFALSVLAPPHLTGDSDSLTNVTATLHGSFTLLCEAAGVPAPTVQWFQE 2360
Query: 1245 GREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXX 1424
G+ I P + ++ A G +L+ + D G Y C ASN AG V
Sbjct: 2361 GQPISPREG-TYLLAGGW-MLKMTQAQEQDRGLYSCLASNEAGEARRNFSV--------- 2409
Query: 1425 XXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIF 1604
V + + I+V E TA G P P V W K G +
Sbjct: 2410 ----EVLVPPSIENEDLEEVIKVPEGQTAQLECNATGHPPPKVTWFK-------DGQSLT 2458
Query: 1605 I----HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ D A L I +++G Y C+A N GE + L V
Sbjct: 2459 VEDPYEMSPDGAFLWIPQANLSNAGHYSCIASNAVGEKTKHTQLSV 2504
Score = 119 bits (298), Expect = 9e-27
Identities = 138/597 (23%), Positives = 217/597 (36%), Gaps = 20/597 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKG--DTKLRPTATYKMHFRNNVATLVFNQVDSND 179
V VG+ A L C +G P V WY+G + L P + TL + D
Sbjct: 722 VLTAVGEEAVLLCAASGVPPPRVIWYRGGLEVILAPG-------DSRSGTLRIPEAQERD 774
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
+G Y C+A N +G+ S+ L V P + +DV +G V C +G P
Sbjct: 775 AGLYTCKAVNELGDASAEIQLVVGN---APRLTDPPQDVTVELGKSVFLTCRATGRPPPI 831
Query: 360 VSWFK-DGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
V+W + DG+ L+ G +T D+ L + Y C A N G A + ARL++
Sbjct: 832 VTWRRGDGQALEPGRGSRTGQRDS-GVLVFERVSLEDQAPYVCEARNVFGKAQAEARLVV 890
Query: 537 T---------EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPI-KVAWAKDNREIRSG 686
T PP + V + G+ C + +P+ + W K + G
Sbjct: 891 TGHGLWVNLEAVGTPPQIANSASVVRVLEGQPVSLTCVILAGRPLPERRWLKAGSPLPPG 950
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLS 866
+ + + S HL + + D G+Y+C A N G +L +
Sbjct: 951 NRHAVR-ADGSLHLD--RALQEDAGRYSCVATNVAGSQHRDVELVV-------------- 993
Query: 867 ETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGD 1046
+G L +G + W K + + + ++ +++Q S D
Sbjct: 994 ------QGVPASLPCIASGVPTPKITWTKETNALTTSGHYSVSRNGTLVIVQ---PSPQD 1044
Query: 1047 AGLYTCKVSNDAGSALCTSSIVIKEPKKPPV-------FDQHLTPVTVSEGEFLQLSCHV 1205
AG Y C +N G + + + KP + D L VTV GE + L C
Sbjct: 1045 AGAYVCTATNSVG--FSSQEMWLSVNTKPMIKMNGSQAVDVPLR-VTVKAGEEVTLDCEA 1101
Query: 1206 RGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTS 1385
+GS + W K + P +G+ L D G Y C ASN AG+ TS
Sbjct: 1102 QGSPTPLLTWTKDANPLLPVTNRYELLPSGS--LRLAQAQVGDNGLYGCTASNPAGA-TS 1158
Query: 1386 KSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK 1565
+ V P+ ++V+ G+P P + W K
Sbjct: 1159 RRYVLRVQVPPQVQPG--------------PRVLKVLAGEALDLNCVAEGNPQPQLNWFK 1204
Query: 1566 GKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ +G + +H +D+GLYRC A N G + L V E
Sbjct: 1205 DGMALMGEGAQGSVH---------FAAVKTSDAGLYRCEASNSAGTDTWKLELLVLE 1252
Score = 112 bits (281), Expect = 8e-25
Identities = 137/580 (23%), Positives = 209/580 (36%), Gaps = 5/580 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V G L C+ G+P VSW K L P + L V D+G
Sbjct: 3387 VMAAQGSEVVLPCEARGSPLPLVSWMKDGEPLLPQSL------EQGPGLKLESVSVGDAG 3440
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C A + GE LTV + PP S + ++ T G + C G P +
Sbjct: 3441 TYSCTAASEAGEARRHFQLTVMD---PPHIEESGETSELSLTPGAHLELLCEARGIPPPN 3497
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W KDG+ L+ N S V + Q D AG Y+C A +P G S R+ +
Sbjct: 3498 ITWHKDGQALRRTEN--DSQAGRVLRVRDVQVDN--AGLYTCLAESPAGEVEKSFRVRV- 3552
Query: 540 EGRNPPFFDIPLAPVDAVVGESAD---FECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
+ PP P P +VVG + EC V ++ W + +++ + +
Sbjct: 3553 --QAPPNVVGPRGP-RSVVGLAPGQLILECSVEAEPAPEIEWHRGGVLLQADAH--THFP 3607
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEG 890
E L + + D G Y+C A N G S ++ I S ++ +V T
Sbjct: 3608 EQGRFLKLQALSTADGGDYSCTARNRAGSTSVAFRVEIHTAPTIQSGPNTVNVSVNRTT- 3666
Query: 891 NSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
L + G V+W K+ + +HP + + F L++ DAG Y C
Sbjct: 3667 ---LLPCQTHGVPTPLVSWRKDGIPLHP-GSPRLEFLPEG-SLRIHPVLAQDAGHYLCLA 3721
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
SN AGS + + E PP + +T++ L C RGS + W K G+
Sbjct: 3722 SNSAGSDRKGLDLRVFE---PPAIAPGPSNLTLTAYSPASLPCEARGSPKPLVTWWKDGQ 3778
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
++ + + L + D+ + C SN G + +VT
Sbjct: 3779 KLDLRLQQGAYRLLPSNALFLTAPSPQDSAQFECVVSNEVGESRRRYQVT---------- 3828
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
V + V G P P V W+K + +G I
Sbjct: 3829 -----VHVPPTIADDQTHFTVTRMAPVILTCHSTGSPTPAVSWSKAGTQLGARGSGYRIL 3883
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
G LEI +G Y C A N G ++ L V
Sbjct: 3884 PSG---ALEIERALPLHAGRYTCTARNSAGVARKHMVLTV 3920
Score = 98.6 bits (244), Expect = 2e-20
Identities = 94/370 (25%), Positives = 150/370 (40%), Gaps = 1/370 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G A L C G+PE ++W K D L A K + + LV N + D+G YIC
Sbjct: 4028 GSHALLPCTAKGSPEPAITWEK-DGHLVSGAEGKFTLQPSGELLVKNS-EGQDAGTYICT 4085
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
AEN+VG LT+ P + D +G + C GS + W +
Sbjct: 4086 AENAVGRARRRVHLTILTL---PVLTTLPGDRSLRLGDRLWLRCVARGSPTPRIGWTIND 4142
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+P+ +G + Q D +TL R +G Y+C A N +G + + + + E P
Sbjct: 4143 QPVTEGVSEQ----DGGSTLQRAAVTREDSGTYTCWAENRVGRVQAVSFVHVKEA--PVL 4196
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
+ + VG S C V G + W KD + ++ + + LTIL+
Sbjct: 4197 QGEAFSYLVEPVGGSIQLHCVVRGDPAPDIHWTKDGLPLPIS---RLHFQLQNGSLTILR 4253
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
D G+Y C AVNE+G + ++ P F + + V G L R
Sbjct: 4254 TKMDDAGRYQCLAVNEMGTVKKVVTVVLQSA---PVFQVE-PQDVTVRSGVDVELRCRAT 4309
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G ++ W + + + +L L+ +A GDAG+Y C N GS
Sbjct: 4310 GEPVPTIEWLRAGRPLQAGRKLR-ALPDGSLWLEHVEA--GDAGVYECVAHNHLGSVTAK 4366
Query: 1101 SSIVIK-EPK 1127
+ + ++ EP+
Sbjct: 4367 ALLAVRGEPR 4376
Score = 95.1 bits (235), Expect = 2e-19
Identities = 97/403 (24%), Positives = 162/403 (40%), Gaps = 9/403 (2%)
Frame = +3
Query: 618 CHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGK 797
C V T P ++ +D + +Q S ++ I + K + G Y C AV+ G
Sbjct: 463 CSVYSTLPFQLQLQRDGERLGEERYFQES---GNSSWEIPRASKAEEGTYQCIAVSRAGS 519
Query: 798 DSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPT 977
+AQ+ I + PP + TV + G + L +V G P ++ W ++ + P
Sbjct: 520 GRASAQIVITDP--PPQLVPGPNVTV--SPGETAILSCQVLGETPYNLTWVRDWRAL-PA 574
Query: 978 ANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT 1157
I+ ++ L L+V+ D G Y C SN G T+ ++++E P +
Sbjct: 575 TTGRISQLSD-LSLEVRSIIPTDGGQYQCVASNPNGVTRATTWLLVREA---PQVSINAR 630
Query: 1158 PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADA 1337
S+G +++SC G I W + G + P D A GT +++ + DA
Sbjct: 631 SQRFSQGVEVRVSCSASGYPTPHISWSREGLAL-PEDSRIHVDAQGTLIIQ--GLAPEDA 687
Query: 1338 GDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATF 1517
G+Y C+A+N G+D + VT + ++P S+ V T
Sbjct: 688 GNYSCQATNEVGTD--EETVT--------------------LYYTDPPSVSAVNAVVLTA 725
Query: 1518 IAK-------VGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAK--LEIRDTTKTDSGL 1670
+ + G P P V W +G G I GD L I + + D+GL
Sbjct: 726 VGEEAVLLCAASGVPPPRVIWYRG--------GLEVILAPGDSRSGTLRIPEAQERDAGL 777
Query: 1671 YRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVL 1799
Y C A N+ G+ + + L V + D+ L K+ L
Sbjct: 778 YTCKAVNELGDASAEIQLVVGNAPRLTDPPQDVTVELGKSVFL 820
>ref|XP_003086264.1| PREDICTED: hemicentin-2 [Mus musculus].
Length = 4154
Score = 173 bits (439), Expect = 4e-43
Identities = 148/594 (24%), Positives = 241/594 (40%), Gaps = 28/594 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT+ + SL C+ P ++W K + A+ + L D+G
Sbjct: 1395 VTVTINNPISLICEALAFPSPNITWMKDGSPFE--ASKNIQLLPGTHGLQILNAQKEDAG 1452
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQ-------LRDVQETVGLPVVFECAVSG 344
+Y C N +GE + + + V +PPS S+ +++V+ V + EC
Sbjct: 1453 QYTCVVTNELGEATKNYHVEVL---IPPSISKDDPLGEVSVKEVKTKVNSSLTLECECWA 1509
Query: 345 SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
+ P S+SW+KDGRP+ P+ + S L L I T S +G+Y C ATN G
Sbjct: 1510 TPPPSISWYKDGRPVT--PSHRLSVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDF 1567
Query: 525 RLILTEGRNPPFFDIPLAPVDA---------------------VVGESADFECHVTGTQP 641
+++ + PP F + VDA V A C P
Sbjct: 1568 NVLI---QVPPMFQ-KMGDVDAGFEPLPHEEEAQGRVTEYREIVENNPAYLYCDTNAIPP 1623
Query: 642 IKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLN 821
++ W ++ + + + +S L+ L + V D G+Y+C A NEVG+D +L
Sbjct: 1624 PELTWYREGQPLSAADG--VSVLQGGRILQLPLVQAEDAGRYSCKAANEVGEDWLHYELL 1681
Query: 822 IKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFK 1001
+ + P T++L E V ++ LE G+ +V+W++N + + P+ ++
Sbjct: 1682 VLTPPVIPGDTQELVEEVTVNASSAVSLECPALGNPAPAVSWFQNGLPVSPSPRLQVL-- 1739
Query: 1002 NNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGE 1181
+L+V A + DA Y C N AGSA ++ ++ P P + D + +T +
Sbjct: 1740 EEGQVLKVATAEVADAASYMCVAENQAGSAEKLFTLKVQVP--PQISDWTTSQLTATLNS 1797
Query: 1182 FLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKAS 1361
+ L C V + W K G+ + GT L AD+G Y+C+A
Sbjct: 1798 SVSLPCEVYAHPNPEVTWYKDGQPLSLGQEA--FLLPGTHTLRLARAQPADSGTYLCEAL 1855
Query: 1362 NVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDP 1541
N AG D ++ ++I+V A + P
Sbjct: 1856 NAAGRDQKMVQLNVLVPPSFKQAPG-----------GPQEAIQVRAGDKAILSCETDSLP 1904
Query: 1542 IPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
P V W K + + L G RI Q G LEI D+ +D G+Y C N GE
Sbjct: 1905 EPAVTWFKDQ-QPLALGQRIQGLQGGQ--TLEILDSQASDKGVYSCKVSNTAGE 1955
Score = 170 bits (431), Expect = 3e-42
Identities = 155/613 (25%), Positives = 241/613 (39%), Gaps = 38/613 (6%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+KV G +A L+C G P V+W+K L Y+M + A L Q + +++G
Sbjct: 1299 IKVPEGQTAQLECNATGHPPPKVTWFKDGQSLTVEDPYEMS--PDGAFLWIPQANLSNAG 1356
Query: 186 EYICRAENSVGEVSSSTFLTVQEQK----LPPSFSRQLRDVQETVGLPVVFECAVSGSEP 353
Y C A N+VGE + T L+V +P + + +V T+ P+ C
Sbjct: 1357 HYSCIASNAVGEKTKHTQLSVLVVPTILGVPEKNANE--EVTVTINNPISLICEALAFPS 1414
Query: 354 ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
+++W KDG P + NIQ L L I + AGQY+C TN +G A+ + +
Sbjct: 1415 PNITWMKDGSPFEASKNIQ--LLPGTHGLQILNAQKEDAGQYTCVVTNELGEATKNYHVE 1472
Query: 534 L----TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
+ + ++ P ++ + V V S EC T P ++W KD R + ++++
Sbjct: 1473 VLIPPSISKDDPLGEVSVKEVKTKVNSSLTLECECWATPPPSISWYKDGRPVTP--SHRL 1530
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK-------- 857
S L L I D+G+Y C A N G+D + I+ +PP F K
Sbjct: 1531 SVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQ---VPPMFQKMGDVDAGF 1587
Query: 858 -----------KLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKN 1004
+++E E E N L P + WY+ + +A ++
Sbjct: 1588 EPLPHEEEAQGRVTEYREIVENNPAYLYCDTNAIPPPELTWYREGQPL--SAADGVSVLQ 1645
Query: 1005 NALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP-VTVSEGE 1181
+LQ+ DAG Y+CK +N+ G +++ P P Q L VTV+
Sbjct: 1646 GGRILQLPLVQAEDAGRYSCKAANEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASS 1705
Query: 1182 FLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKAS 1361
+ L C G+ + W + G + PS R VL+ ADA Y+C A
Sbjct: 1706 AVSLECPALGNPAPAVSWFQNGLPVSPSPR--LQVLEEGQVLKVATAEVADAASYMCVAE 1763
Query: 1362 NVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIA------ 1523
N AGS KLF + ++ + TT+ A
Sbjct: 1764 NQAGSAE------------------------KLFTLKVQVPPQISDWTTSQLTATLNSSV 1799
Query: 1524 ----KVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFN 1691
+V P P V W K + L+ G F+ L + DSG Y C A N
Sbjct: 1800 SLPCEVYAHPNPEVTWYKDG-QPLSLGQEAFLLP--GTHTLRLARAQPADSGTYLCEALN 1856
Query: 1692 KHGEIESNVNLQV 1730
G + V L V
Sbjct: 1857 AAGRDQKMVQLNV 1869
Score = 158 bits (400), Expect = 1e-38
Identities = 149/583 (25%), Positives = 233/583 (39%), Gaps = 17/583 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + +L C G P V+W + + ++ +N+ +L + ++ +G
Sbjct: 1112 VSVIQDGNTTLACNATGKPLPVVTWQRDGQPVSVEPGLRLQNQNH--SLHVERAQASHAG 1169
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C AEN+ G L+V S L +V T+ C +G +V
Sbjct: 1170 GYSCVAENTAGRAERRFALSVLAPPHLTGDSDSLTNVTATLHGSFTLLCEAAGVPAPTVQ 1229
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WF++G+P+ P T L L + Q G YSC A+N G A R E
Sbjct: 1230 WFQEGQPI--SPREGTYLLAGGWMLKMTQAQEQDRGLYSCLASNEAGEA---RRNFSVEV 1284
Query: 546 RNPPFFDIPLAPVDAVV----GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
PP I ++ V+ G++A EC+ TG P KV W KD + + Y++S
Sbjct: 1285 LVPP--SIENEDLEEVIKVPEGQTAQLECNATGHPPPKVTWFKDGQSLTVEDPYEMS--P 1340
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF----TKKLSETVEE 881
+ A L I + + + G Y+C A N VG+ + QL++ L+ P+ K +E V
Sbjct: 1341 DGAFLWIPQANLSNAGHYSCIASNAVGEKTKHTQLSV---LVVPTILGVPEKNANEEVTV 1397
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
T N L ++ W K+ + N ++ + LQ+ A DAG YT
Sbjct: 1398 TINNPISLICEALAFPSPNITWMKDGSPFEASKNIQLLPGTHG--LQILNAQKEDAGQYT 1455
Query: 1062 CKVSNDAGSALCTSSIVIKEP----KKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRI 1229
C V+N+ G A + + P K P+ + + V L L C + P I
Sbjct: 1456 CVVTNELGEATKNYHVEVLIPPSISKDDPLGEVSVKEVKTKVNSSLTLECECWATPPPSI 1515
Query: 1230 QWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXX 1409
W K GR + PS R S +L+ + +D+G Y+C A+NVAG D V
Sbjct: 1516 SWYKDGRPVTPSHR--LSVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQV 1573
Query: 1410 XXXXXXXXXXXXVDGKLFFVSEPQS-----IRVVEKTTATFIAKVGGDPIPNVKWTKGKW 1574
L E Q +VE A P P + W + +
Sbjct: 1574 PPMFQKMGDVDAGFEPLPHEEEAQGRVTEYREIVENNPAYLYCDTNAIPPPELTWYR-EG 1632
Query: 1575 RQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
+ L+ + + Q G +L + D+G Y C A N+ GE
Sbjct: 1633 QPLSAADGVSVLQGGRILQLPL--VQAEDAGRYSCKAANEVGE 1673
Score = 156 bits (395), Expect = 5e-38
Identities = 153/579 (26%), Positives = 229/579 (39%), Gaps = 12/579 (2%)
Frame = +3
Query: 36 LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSV 215
L C+ G P ++W K L + F + +TLV + + DSG Y C A N
Sbjct: 2167 LHCEAEGQPPPDITWLKDGGLLDQHVGPHLRFYLDGSTLVLKGLRTADSGAYTCVAHNPA 2226
Query: 216 GEVSSSTFLTVQEQKLPPSFSRQLRDVQETV---GLPVVFECAVSGSEPISVSWFKDGRP 386
GE + + V +PP+ +Q D V G V C V GS PI VSW KDG P
Sbjct: 2227 GEDARLHTVNV---LVPPTIKQQAGDTGTLVSRTGELVTMVCPVQGSPPIHVSWLKDGLP 2283
Query: 387 LKDGPNIQTSFLDNVA-TLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFF 563
L P Q + L + TL I Q + +G ++C A +P G A + L++ PP
Sbjct: 2284 L---PLSQRTLLHSSGRTLRISQVQLADSGVFTCVAASPAGVADRNFTLLVLV---PPI- 2336
Query: 564 DIPLAPVD------AVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
L PV+ A G C G+ V+W KD + LE
Sbjct: 2337 ---LEPVEFQNNVMAAQGSEVVLPCEARGSPLPLVSWMKDGEPLLP------QSLEQGPG 2387
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE--ETEGNSF 899
L + V GD G Y+C A +E G+ QL + + P ++ ET E T G
Sbjct: 2388 LKLESVSVGDAGTYSCTAASEAGEARRHFQLTVMD----PPHIEESGETSELSLTPGAHL 2443
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L G P ++ W+K+ + T N +L+V+ + +AGLYTC +
Sbjct: 2444 ELLCEARGIPPPNITWHKDGQALRRTEN----DSQAGRVLRVRDVQVDNAGLYTCLAESP 2499
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AG + + ++ P + V ++ G+ + L C V I+W + G ++
Sbjct: 2500 AGEVEKSFRVRVQAPPNVVGPRGPRSVVGLAPGQLI-LECSVEAEPAPEIEWHRGGVLLQ 2558
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
F L+ + ++ AD GDY C A N AGS + +V
Sbjct: 2559 AD--AHTHFPEQGRFLKLQALSTADGGDYSCTARNRAGSTSVAFRV-------------- 2602
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
+ S P ++ V T + G P P V W K R+ +G
Sbjct: 2603 -EIHTAPTIQSGPNTVNVSVNRTTLLPCQTHGVPTPLVSWRKDGIPLHPGSPRLEFLPEG 2661
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
L I D+G Y C+A N G ++L+V E
Sbjct: 2662 ---SLRIHPVLAQDAGHYLCLASNSAGSDRKGLDLRVFE 2697
Score = 155 bits (393), Expect = 8e-38
Identities = 150/589 (25%), Positives = 234/589 (39%), Gaps = 13/589 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G +A L C+ G P ++WYK T L P++ ++ + L + +D+G
Sbjct: 350 VTVLEGHTAQLLCEARGMPSPAITWYKDGTLLAPSS--EVVYSKGGRQLQLVKAQPSDAG 407
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRD---VQETVGLPVVFECAVSGSEPI 356
Y C+A N G ST L V +PP+ VQ G PV EC G P
Sbjct: 408 LYTCQASNPAGITKKSTSLEVY---VPPTIEGADGGPYLVQAVAGRPVALECVARGHPPP 464
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSA-------- 512
++SW +G P+ D ++L+ L + + G YSC A++P G A
Sbjct: 465 TISWQHEGLPVVDS---NGTWLEAGGALQLENPGEASGGLYSCVASSPAGEAVLQYSVEM 521
Query: 513 SSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
+L++ EG + V A VG+S D C +G+ + W ++ R
Sbjct: 522 QVPPQLLVAEG---------MGQVTATVGQSLDLPCQASGSPVPTIQWLQNGRPAEELAG 572
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET 872
Q++ H++ V+ +G + C A NE G ++++ E PS E
Sbjct: 573 VQLASQGTILHIS--HVELNHSGLFACQATNEAGTAGAEVEVSVHEL---PSVHIIGGEN 627
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAG 1052
+ L+ G S+ W+K+ V + + LQ++KA + D G
Sbjct: 628 LTAPFLQPVTLQCVGIGVPTPSLRWWKDGVAVATSGG----------NLQIEKADLRDEG 677
Query: 1053 LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQ 1232
+YTC +N AG + V + PP + V E + L C G P +
Sbjct: 678 VYTCSATNLAGE---SKKDVTLKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVS 734
Query: 1233 WLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXX 1412
W K + I R S A+G VL + V +DAG Y C A+NVAGS K +
Sbjct: 735 WFKGRQPISTQRRVIVS-ADG-RVLHIERVQLSDAGSYRCVATNVAGSAGLKYGLRVNVP 792
Query: 1413 XXXXXXXXXXXVDGKLFFVSEPQSI--RVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLN 1586
++ P ++ V+ T G P P + W K ++
Sbjct: 793 PR----------------ITLPPNLPGPVLLGTPFRLTCNATGTPRPTLIWLK-DGNPVS 835
Query: 1587 QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
G + L + +DSG Y CVA + GE +V LQV+
Sbjct: 836 PEGIPGLKVFPGGQVLTVASARASDSGSYSCVAVSAVGEDRRDVILQVH 884
Score = 153 bits (386), Expect = 5e-37
Identities = 158/645 (24%), Positives = 247/645 (38%), Gaps = 75/645 (11%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVA-----TLVFNQVDSNDSG 185
G++ASL C GTP+ ++W +G + + ++ R +VA +L + V DSG
Sbjct: 112 GENASLPCPAQGTPKPRITWRRGPS------SEPLNGRPDVAVLDEGSLFLSSVSLADSG 165
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQ--------------------------- 284
EY C+A N VG S L V +PPS +
Sbjct: 166 EYECQATNEVGSASRRAKLVVY---VPPSIREEGHITNVSGLAGQPLTLECDINGFPAPE 222
Query: 285 ---LRD------------------------VQETVGLP---VVFECAVSGSEPISVSWFK 374
L+D QE +GL V EC SG V W K
Sbjct: 223 VAWLKDGQLVGDSGGGWDGEVPPSLLGAGAAQEVLGLAGADVTLECQTSGVPTPQVEWTK 282
Query: 375 DGRPLKDG-PNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
DG+P+ G P+I ++ L I + GQY C +P G + +L + +
Sbjct: 283 DGQPILPGDPHILLQ--EDGQVLRIISSHLGDEGQYQCVVFSPAGQQAKDFQLSI---HS 337
Query: 552 PP--FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP + V + G +A C G + W KD + ++ Y +
Sbjct: 338 PPTIWGSNETGEVTVLEGHTAQLLCEARGMPSPAITWYKDGTLLAPSS--EVVYSKGGRQ 395
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF--TKKLSETVEETEGNSF 899
L ++K D G YTC A N G + L + +PP+ V+ G
Sbjct: 396 LQLVKAQPSDAGLYTCQASNPAGITKKSTSLEV---YVPPTIEGADGGPYLVQAVAGRPV 452
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
LE G P +++W + P + T+ LQ++ GLY+C S+
Sbjct: 453 ALECVARGHPPPTISWQHEGL---PVVDSNGTWLEAGGALQLENPGEASGGLYSCVASSP 509
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AG A+ S+ ++ P + V + + VT + G+ L L C GS IQWL+ GR +
Sbjct: 510 AGEAVLQYSVEMQVPPQLLV-AEGMGQVTATVGQSLDLPCQASGSPVPTIQWLQNGRPAE 568
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
+ A+ +L V +G + C+A+N AG+ ++ +V+
Sbjct: 569 --ELAGVQLASQGTILHISHVELNHSGLFACQATNEAGTAGAEVEVS------------- 613
Query: 1440 XXVDGKLFFVSEPQSIRVV--EKTTATFIAKVG------GDPIPNVKWTKGKWRQLNQGG 1595
V E S+ ++ E TA F+ V G P P+++W K GG
Sbjct: 614 ---------VHELPSVHIIGGENLTAPFLQPVTLQCVGIGVPTPSLRWWKDGVAVATSGG 664
Query: 1596 RIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
L+I D G+Y C A N GE + +V L+V
Sbjct: 665 -----------NLQIEKADLRDEGVYTCSATNLAGESKKDVTLKV 698
Score = 149 bits (376), Expect = 8e-36
Identities = 151/610 (24%), Positives = 233/610 (38%), Gaps = 5/610 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VT G +A L C G P +SW K L L Q S G Y
Sbjct: 1018 VTEGQTARLSCDCQGIPFPKISWRKDGQPLPGEGDSLEQVLAVGRLLYLGQAQSAQEGTY 1077
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C N+ G S L V L V C +G V+W
Sbjct: 1078 TCECSNAAGTSSQEQSLEVLVPPQVTGLWEPLTTVSVIQDGNTTLACNATGKPLPVVTWQ 1137
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
+DG+P+ P ++ ++ +L++ + S AG YSC A N G A L + +
Sbjct: 1138 RDGQPVSVEPGLRLQNQNH--SLHVERAQASHAGGYSCVAENTAGRAERRFALSVLAPPH 1195
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSG-GNYQISYLENSAHL 728
L V A + S C G V W ++ + I G Y L L
Sbjct: 1196 LTGDSDSLTNVTATLHGSFTLLCEAAGVPAPTVQWFQEGQPISPREGTY---LLAGGWML 1252
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIK-ERLIPPSFTKK-LSETVEETEGNSFR 902
+ + + D G Y+C A NE G+ A+ N E L+PPS + L E ++ EG + +
Sbjct: 1253 KMTQAQEQDRGLYSCLASNEAGE----ARRNFSVEVLVPPSIENEDLEEVIKVPEGQTAQ 1308
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE G P V W+K+ + T + L + +A++ +AG Y+C SN
Sbjct: 1309 LECNATGHPPPKVTWFKDGQSL--TVEDPYEMSPDGAFLWIPQANLSNAGHYSCIASNAV 1366
Query: 1083 GSALCTSSI-VIKEPKKPPVFDQHLTP-VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
G + + V+ P V +++ VTV+ + L C I W+K G
Sbjct: 1367 GEKTKHTQLSVLVVPTILGVPEKNANEEVTVTINNPISLICEALAFPSPNITWMKDGSPF 1426
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
+ S + GT L+ + K DAG Y C +N G T V
Sbjct: 1427 EASK--NIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEATKNYHVEVLIPPSISKDDP 1484
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
V K ++ ++ T + P P++ W K R + R+ +
Sbjct: 1485 LGEVSVK--------EVKTKVNSSLTLECECWATPPPSISWYKDG-RPVTPSHRLSV--L 1533
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPV 1796
G+ L+I+ T +DSG Y CVA N GE + + N+ + +K+ GD+ A + P
Sbjct: 1534 GEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKM-GDVDAGFEPLPH 1592
Query: 1797 LKKGAGEEEE 1826
++ G E
Sbjct: 1593 EEEAQGRVTE 1602
Score = 147 bits (370), Expect = 4e-35
Identities = 151/598 (25%), Positives = 232/598 (38%), Gaps = 32/598 (5%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENS 212
+LQC G P + W+K + + L + D D G Y C A N
Sbjct: 637 TLQCVGIGVPTPSLRWWKDGVAVATSG----------GNLQIEKADLRDEGVYTCSATNL 686
Query: 213 VGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLK 392
GE L V +PP+ + V EC SG P VSWFK +P+
Sbjct: 687 AGESKKDVTLKVL---VPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGRQPIS 743
Query: 393 DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIP 572
+ S V L+I + S AG Y C ATN GSA L + PP +P
Sbjct: 744 TQRRVIVSADGRV--LHIERVQLSDAGSYRCVATNVAGSAGLKYGLRVNV---PPRITLP 798
Query: 573 L-APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDK 749
P ++G C+ TGT + W KD + G + LT+
Sbjct: 799 PNLPGPVLLGTPFRLTCNATGTPRPTLIWLKDGNPVSPEGIPGLKVFPGGQVLTVASARA 858
Query: 750 GDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKLSETVEETEGNSFRLEGRVAGS 926
D+G Y+C AV+ VG+D L + +PPS ++L+ +V E S LE +
Sbjct: 859 SDSGSYSCVAVSAVGEDRRDVILQVH---MPPSILGEELNMSVVVNE--SVTLECQSHAV 913
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALL---------------------------LQV 1025
P + W K+ + P ++ + ALL + V
Sbjct: 914 PPPVLRWQKDGRPLQPHPGIRLS-ADKALLEVCHSVAGCPGELNEQGRAGQDLRVSQVPV 972
Query: 1026 KKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHV 1205
+A++ DAG YTC+ N AG + ++ + P P + + +TV+EG+ +LSC
Sbjct: 973 DRAAVWDAGHYTCEAINQAGRSEKHFNLHVWVPPAFPSKEPY--TLTVTEGQTARLSCDC 1030
Query: 1206 RGSEPIRIQWLKAGREIK-PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
+G +I W K G+ + D A G +L A G Y C+ SN AG+ +
Sbjct: 1031 QGIPFPKISWRKDGQPLPGEGDSLEQVLAVG-RLLYLGQAQSAQEGTYTCECSNAAGTSS 1089
Query: 1383 SKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEP-QSIRVVEKTTATFIAKVGGDPIPNVKW 1559
+ + V ++ + EP ++ V++ T G P+P V W
Sbjct: 1090 QEQSL-------------EVLVPPQVTGLWEPLTTVSVIQDGNTTLACNATGKPLPVVTW 1136
Query: 1560 TK-GKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ G+ + G R+ + L + + +G Y CVA N G E L V
Sbjct: 1137 QRDGQPVSVEPGLRL----QNQNHSLHVERAQASHAGGYSCVAENTAGRAERRFALSV 1190
Score = 139 bits (349), Expect = 1e-32
Identities = 146/585 (24%), Positives = 239/585 (40%), Gaps = 8/585 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V+V + L CQ G P VSW K L P + ++ F +L + V + D+G
Sbjct: 2617 VNVSVNRTTLLPCQTHGVPTPLVSWRKDGIPLHPGSP-RLEFLPE-GSLRIHPVLAQDAG 2674
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y+C A NS G L V E PP+ + ++ T P C GS V+
Sbjct: 2675 HYLCLASNSAGSDRKGLDLRVFE---PPAIAPGPSNLTLTAYSPASLPCEARGSPKPLVT 2731
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRS--FAGQYSCTATNPIGSASSSARLIL- 536
W+KDG+ L +Q + + +F T S + Q+ C +N +G + ++ +
Sbjct: 2732 WWKDGQKLD--LRLQQGAYRLLPSNALFLTAPSPQDSAQFECVVSNEVGESRRRYQVTVH 2789
Query: 537 ---TEGRNPPFFDIP-LAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRS-GGNYQI 701
T + F + +APV CH TG+ V+W+K ++ + G Y+I
Sbjct: 2790 VPPTIADDQTHFTVTRMAPVILT--------CHSTGSPTPAVSWSKAGTQLGARGSGYRI 2841
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
S L I + G+YTC A N G L ++ + K L V+
Sbjct: 2842 L---PSGALEIERALPLHAGRYTCTARNSAGVARKHMVLTVQASPV----VKPLPSVVQV 2894
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
L +G V W K + I A+ ++ L++ AS DAG Y
Sbjct: 2895 VASEEVLLPCEASGIPQPMVIWQKEGLSIPEGAHMQVLPSGQ---LRIMHASPEDAGNYF 2951
Query: 1062 CKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLK 1241
C N GSA+ + +V+ + PPV + L ++ EG L C +GS I W K
Sbjct: 2952 CIAQNSVGSAMAKTRLVV---QVPPVIENGLPDLSTIEGSHALLPCTAKGSPEPAITWEK 3008
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
G + ++ F+ +L K+ DAG Y+C A N G + +T
Sbjct: 3009 DGHLVSGAEG-KFTLQPSGELL-VKNSEGQDAGTYICTAENAVGRARRRVHLTILTLPV- 3065
Query: 1422 XXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRI 1601
L + +S+R+ ++ +A+ G P P + WT + + +G
Sbjct: 3066 ------------LTTLPGDRSLRLGDRLWLRCVAR--GSPTPRIGWTIND-QPVTEG--- 3107
Query: 1602 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ ++ + L+ T+ DSG Y C A N+ G +++ + V E
Sbjct: 3108 -VSEQDGGSTLQRAAVTREDSGTYTCWAENRVGRVQAVSFVHVKE 3151
Score = 136 bits (343), Expect = 5e-32
Identities = 154/650 (23%), Positives = 254/650 (39%), Gaps = 63/650 (9%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYK-GDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
+KV G++ L C G P+ ++W+K G + A +HF V ++D+
Sbjct: 20 LKVLAGEALDLNCVAEGNPQPQLNWFKDGMALMGEGAQGSVHFA---------AVKTSDA 70
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSR-QLRDVQETV-GLPVVFECAVSGSEPI 356
G Y C A NS G + L V E PP + + + + E V G C G+
Sbjct: 71 GLYRCEASNSAGTDTWKLELLVLE---PPHWGTDETKSLLERVAGENASLPCPAQGTPKP 127
Query: 357 SVSWFK--DGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
++W + PL P++ + LD +L + + +G+Y C ATN +GSAS A+L
Sbjct: 128 RITWRRGPSSEPLNGRPDV--AVLDE-GSLFLSSVSLADSGEYECQATNEVGSASRRAKL 184
Query: 531 ILTEGRNPPFF--DIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI-RSGGNY-- 695
++ PP + + V + G+ EC + G +VAW KD + + SGG +
Sbjct: 185 VVYV---PPSIREEGHITNVSGLAGQPLTLECDINGFPAPEVAWLKDGQLVGDSGGGWDG 241
Query: 696 -----------------------------------QISY-------LENSAHL------T 731
Q+ + L H+
Sbjct: 242 EVPPSLLGAGAAQEVLGLAGADVTLECQTSGVPTPQVEWTKDGQPILPGDPHILLQEDGQ 301
Query: 732 ILKVDKGDTG---QYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET--EGNS 896
+L++ G QY C + G+ + QL+I PP+ +ET E T EG++
Sbjct: 302 VLRIISSHLGDEGQYQCVVFSPAGQQAKDFQLSIHS---PPTIWGS-NETGEVTVLEGHT 357
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
+L G ++ WYK+ + P++ E+ + LQ+ KA DAGLYTC+ SN
Sbjct: 358 AQLLCEARGMPSPAITWYKDGTLLAPSS--EVVYSKGGRQLQLVKAQPSDAGLYTCQASN 415
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
AG ++S+ + P D V G + L C RG P I W G +
Sbjct: 416 PAGITKKSTSLEVYVPPTIEGADGGPYLVQAVAGRPVALECVARGHPPPTISWQHEGLPV 475
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
S+ ++ L+ ++ +A G Y C AS+ AG + V
Sbjct: 476 VDSNG---TWLEAGGALQLENPGEASGGLYSCVASSPAGEAVLQYSV------------- 519
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
V +L + + + G P+P ++W + R + + + +
Sbjct: 520 EMQVPPQLLVAEGMGQVTATVGQSLDLPCQASGSPVPTIQWLQ-NGRPAEELAGVQLASQ 578
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGD 1766
G L I SGL+ C A N+ G + V + V+E I G+
Sbjct: 579 G--TILHISHVELNHSGLFACQATNEAGTAGAEVEVSVHELPSVHIIGGE 626
Score = 136 bits (343), Expect = 5e-32
Identities = 113/418 (27%), Positives = 177/418 (42%), Gaps = 7/418 (1%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
++ + A L C P ++WY+ L +A + L V + D+G
Sbjct: 1605 EIVENNPAYLYCDTNAIPPPELTWYREGQPL--SAADGVSVLQGGRILQLPLVQAEDAGR 1662
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQL-RDVQETVGLPVVFECAVSGSEPISVS 365
Y C+A N VGE L V + P +++L +V V EC G+ +VS
Sbjct: 1663 YSCKAANEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPALGNPAPAVS 1722
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WF++G P+ P +Q L+ L + + + A Y C A N GSA +L +
Sbjct: 1723 WFQNGLPVSPSPRLQV--LEEGQVLKVATAEVADAASYMCVAENQAGSAE---KLFTLKV 1777
Query: 546 RNPP-FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ PP D + + A + S C V +V W KD + + G Q ++L
Sbjct: 1778 QVPPQISDWTTSQLTATLNSSVSLPCEVYAHPNPEVTWYKDGQPLSLG---QEAFLLPGT 1834
Query: 723 H-LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLS---ETVEETEG 890
H L + + D+G Y C A+N G+D QLN+ L+PPSF + E ++ G
Sbjct: 1835 HTLRLARAQPADSGTYLCEALNAAGRDQKMVQLNV---LVPPSFKQAPGGPQEAIQVRAG 1891
Query: 891 NSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
+ L +V W+K+ + I L++ + D G+Y+CKV
Sbjct: 1892 DKAILSCETDSLPEPAVTWFKDQQPL--ALGQRIQGLQGGQTLEILDSQASDKGVYSCKV 1949
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFDQ-HLTPVTVSEGEFLQLSCHVRGSEPIRIQWLK 1241
SN AG A+ T + I + PP F++ V G L L+C V G + WLK
Sbjct: 1950 SNTAGEAIRTFVLAI---QVPPTFEKPERETVNQVAGRTLVLACDVSGIPAPTVTWLK 2004
Score = 136 bits (342), Expect = 7e-32
Identities = 135/577 (23%), Positives = 224/577 (38%), Gaps = 6/577 (1%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G +L+CQ +G P V W K + P + + + + + D G+Y C
Sbjct: 261 GADVTLECQTSGVPTPQVEWTKDGQPILPGDPHILLQEDGQVLRIISS-HLGDEGQYQCV 319
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPISVSWFK 374
+ G+ + L++ PP+ S + +V G C G +++W+K
Sbjct: 320 VFSPAGQQAKDFQLSIHS---PPTIWGSNETGEVTVLEGHTAQLLCEARGMPSPAITWYK 376
Query: 375 DGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNP 554
DG L P+ + + L + + S AG Y+C A+NP G S L +
Sbjct: 377 DGTLL--APSSEVVYSKGGRQLQLVKAQPSDAGLYTCQASNPAGITKKSTSLEVYVPPTI 434
Query: 555 PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTI 734
D V AV G EC G P ++W + + ++LE L +
Sbjct: 435 EGADGGPYLVQAVAGRPVALECVARGHPPPTISWQHEGLPVVDSNG---TWLEAGGALQL 491
Query: 735 LKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGR 914
+ G Y+C A + G+ Q +++ ++ P + V T G S L +
Sbjct: 492 ENPGEASGGLYSCVASSPAGE--AVLQYSVEMQVPPQLLVAEGMGQVTATVGQSLDLPCQ 549
Query: 915 VAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSAL 1094
+GS ++ W +N A ++ + +L + + +GL+ C+ +N+AG+A
Sbjct: 550 ASGSPVPTIQWLQNGRPAEELAGVQLA--SQGTILHISHVELNHSGLFACQATNEAGTAG 607
Query: 1095 CTSSIVIKE-PKKPPVFDQHLTPVTVSEGEFLQ---LSCHVRGSEPIRIQWLKAGREIKP 1262
+ + E P + ++LT FLQ L C G ++W K G +
Sbjct: 608 AEVEVSVHELPSVHIIGGENLT------APFLQPVTLQCVGIGVPTPSLRWWKDGVAVAT 661
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S G +E D+ D G Y C A+N+AG SK VT
Sbjct: 662 S--------GGNLQIEKADLR--DEGVYTCSATNLAGE--SKKDVTLKVLVPPNIEPG-- 707
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
P + V+E + T G P P+V W KG+ + ++ R+ + D
Sbjct: 708 -----------PVNKAVLENASVTLECLASGVPPPDVSWFKGR-QPISTQRRVIV--SAD 753
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
L I +D+G YRCVA N G L+VN
Sbjct: 754 GRVLHIERVQLSDAGSYRCVATNVAGSAGLKYGLRVN 790
Score = 135 bits (341), Expect = 9e-32
Identities = 153/610 (25%), Positives = 221/610 (36%), Gaps = 34/610 (5%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P V +G L C GTP + W K + P + L ++DS
Sbjct: 802 PGPVLLGTPFRLTCNATGTPRPTLIWLKDGNPVSPEGIPGLKVFPGGQVLTVASARASDS 861
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y C A ++VGE L V +PPS + ++ V V EC P +
Sbjct: 862 GSYSCVAVSAVGEDRRDVILQVH---MPPSILGEELNMSVVVNESVTLECQSHAVPPPVL 918
Query: 363 SWFKDGRPLKDGPNIQTS-------FLDNVA--------------TLNIFQ--TDRSF-- 467
W KDGRPL+ P I+ S +VA L + Q DR+
Sbjct: 919 RWQKDGRPLQPHPGIRLSADKALLEVCHSVAGCPGELNEQGRAGQDLRVSQVPVDRAAVW 978
Query: 468 -AGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVV--GESADFECHVTGTQ 638
AG Y+C A N G + L + PP F P V G++A C G
Sbjct: 979 DAGHYTCEAINQAGRSEKHFNLHVWV---PPAFP-SKEPYTLTVTEGQTARLSCDCQGIP 1034
Query: 639 PIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQL 818
K++W KD + + G+ L L + + G YTC N G S L
Sbjct: 1035 FPKISWRKDGQPLPGEGDSLEQVLAVGRLLYLGQAQSAQEGTYTCECSNAAGTSSQEQSL 1094
Query: 819 NIKERLIPPSFTK--KLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEI 992
+ L+PP T + TV + + L G V W ++ + +
Sbjct: 1095 EV---LVPPQVTGLWEPLTTVSVIQDGNTTLACNATGKPLPVVTWQRDGQPVSVEPGLRL 1151
Query: 993 TFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVS 1172
+N++ L V++A AG Y+C N AG A ++ + P LT VT +
Sbjct: 1152 QNQNHS--LHVERAQASHAGGYSCVAENTAGRAERRFALSVLAPPHLTGDSDSLTNVTAT 1209
Query: 1173 EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVC 1352
L C G +QW + G+ I P + ++ A G +L+ + D G Y C
Sbjct: 1210 LHGSFTLLCEAAGVPAPTVQWFQEGQPISPREG-TYLLAGGW-MLKMTQAQEQDRGLYSC 1267
Query: 1353 KASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVG 1532
ASN AG V V + + I+V E TA
Sbjct: 1268 LASNEAGEARRNFSV-------------EVLVPPSIENEDLEEVIKVPEGQTAQLECNAT 1314
Query: 1533 GDPIPNVKWTKGKWRQLNQGGRIFI----HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG 1700
G P P V W K G + + D A L I +++G Y C+A N G
Sbjct: 1315 GHPPPKVTWFK-------DGQSLTVEDPYEMSPDGAFLWIPQANLSNAGHYSCIASNAVG 1367
Query: 1701 EIESNVNLQV 1730
E + L V
Sbjct: 1368 EKTKHTQLSV 1377
Score = 134 bits (338), Expect = 2e-31
Identities = 151/613 (24%), Positives = 230/613 (37%), Gaps = 18/613 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + SL+C G P VSW++ + P+ ++ V + +V D+
Sbjct: 1699 VTVNASSAVSLECPALGNPAPAVSWFQNGLPVSPSPRLQVLEEGQVLKVATAEVA--DAA 1756
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSR-QLRDVQETVGLPVVFECAVSGSEPISV 362
Y+C AEN G L VQ +PP S + T+ V C V V
Sbjct: 1757 SYMCVAENQAGSAEKLFTLKVQ---VPPQISDWTTSQLTATLNSSVSLPCEVYAHPNPEV 1813
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W+KDG+PL G + L TL + + + +G Y C A N G +L +
Sbjct: 1814 TWYKDGQPLSLGQ--EAFLLPGTHTLRLARAQPADSGTYLCEALNAAGRDQKMVQLNVLV 1871
Query: 543 GRNPPFFDIPLAPVDAV---VGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
P F P P +A+ G+ A C V W KD + + G +I L+
Sbjct: 1872 P--PSFKQAPGGPQEAIQVRAGDKAILSCETDSLPEPAVTWFKDQQPLALG--QRIQGLQ 1927
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN 893
L IL D G Y+C N G+ T L I+ +PP+F K ETV + G
Sbjct: 1928 GGQTLEILDSQASDKGVYSCKVSNTAGEAIRTFVLAIQ---VPPTFEKPERETVNQVAGR 1984
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASM--GDAGLYTCK 1067
+ L V+G +V W K+ + + ALLL + + ++ G C+
Sbjct: 1985 TLVLACDVSGIPAPTVTWLKDRLPV-------------ALLLTLDRYTLLGSVGGSSACQ 2031
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
+ N + P + PV + EG S+P+ Q+
Sbjct: 2032 LVNPMAHSTKAVPCWTSLPPASSCGRRETRPVEIYEG----------ASDPLVPQFPCQY 2081
Query: 1248 REIKPSDRCSFSFANGTAV---------LEFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
R+ R S + V L+ + A AG Y C A N A ++ K V
Sbjct: 2082 RKEVQDSRASLHSTESSVVHGVVSRGGRLQLSHLQPAQAGTYTCVAEN-AQAEARKDFVV 2140
Query: 1401 XXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWR 1577
V ++ Q V+EK + G P P++ W K G
Sbjct: 2141 SVL------------VPPQIQDSGMAQEHNVLEKQEIRLHCEAEGQPPPDITWLKDGGLL 2188
Query: 1578 QLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIE--SNVNLQVNERKKQE 1751
+ G + + G + L ++ DSG Y CVA N GE VN+ V KQ+
Sbjct: 2189 DQHVGPHLRFYLDG--STLVLKGLRTADSGAYTCVAHNPAGEDARLHTVNVLVPPTIKQQ 2246
Query: 1752 KIEGDLRAMLKKT 1790
GD ++ +T
Sbjct: 2247 --AGDTGTLVSRT 2257
Score = 133 bits (334), Expect = 6e-31
Identities = 151/604 (25%), Positives = 234/604 (38%), Gaps = 29/604 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++V GD A L C+ PE V+W+K L ++ TL ++D G
Sbjct: 1886 IQVRAGDKAILSCETDSLPEPAVTWFKDQQPL--ALGQRIQGLQGGQTLEILDSQASDKG 1943
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRD-VQETVGLPVVFECAVSGSEPISV 362
Y C+ N+ GE + L +Q +PP+F + R+ V + G +V C VSG +V
Sbjct: 1944 VYSCKVSNTAGEAIRTFVLAIQ---VPPTFEKPERETVNQVAGRTLVLACDVSGIPAPTV 2000
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGS----------- 509
+W KD P+ + TL+ + S G +C NP+
Sbjct: 2001 TWLKDRLPVA-----------LLLTLDRYTLLGSVGGSSACQLVNPMAHSTKAVPCWTSL 2049
Query: 510 --ASSSAR-----LILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDN 668
ASS R + + EG + P +P P E D + T+ V +
Sbjct: 2050 PPASSCGRRETRPVEIYEGASDPL--VPQFPCQ-YRKEVQDSRASLHSTESSVV-----H 2101
Query: 669 REIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVN---EVGKDSCTAQLNIKERLI 839
+ GG Q+S+L+ + G YTC A N E KD + L +
Sbjct: 2102 GVVSRGGRLQLSHLQPA-----------QAGTYTCVAENAQAEARKDFVVSVL------V 2144
Query: 840 PPSFTKK-LSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALL 1016
PP +++ E RL G P + W K+ + + F +
Sbjct: 2145 PPQIQDSGMAQEHNVLEKQEIRLHCEAEGQPPPDITWLKDGGLLDQHVGPHLRFYLDGST 2204
Query: 1017 LQVKKASMGDAGLYTCKVSNDAG--SALCTSSIVIKEPKKPPVFDQHL--TPVTVSE-GE 1181
L +K D+G YTC N AG + L T ++++ PP Q T VS GE
Sbjct: 2205 LVLKGLRTADSGAYTCVAHNPAGEDARLHTVNVLV-----PPTIKQQAGDTGTLVSRTGE 2259
Query: 1182 FLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKAS 1361
+ + C V+GS PI + WLK G + S R + T L V AD+G + C A+
Sbjct: 2260 LVTMVCPVQGSPPIHVSWLKDGLPLPLSQRTLLHSSGRT--LRISQVQLADSGVFTCVAA 2317
Query: 1362 NVAG-SDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGD 1538
+ AG +D + + + V L V ++ + + + G
Sbjct: 2318 SPAGVADRNFTLLV--------------LVPPILEPVEFQNNVMAAQGSEVVLPCEARGS 2363
Query: 1539 PIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNV 1718
P+P V W K L Q ++G KLE + D+G Y C A ++ GE +
Sbjct: 2364 PLPLVSWMKDGEPLLPQS-----LEQGPGLKLE--SVSVGDAGTYSCTAASEAGEARRHF 2416
Query: 1719 NLQV 1730
L V
Sbjct: 2417 QLTV 2420
Score = 132 bits (331), Expect = 1e-30
Identities = 149/581 (25%), Positives = 220/581 (37%), Gaps = 6/581 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ +T G L C+ G P ++W+K LR T R L V +++G
Sbjct: 2435 LSLTPGAHLELLCEARGIPPPNITWHKDGQALRRTENDSQAGR----VLRVRDVQVDNAG 2490
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGL---PVVFECAVSGSEPI 356
Y C AE+ GEV S + VQ PP+ R + VGL ++ EC+V
Sbjct: 2491 LYTCLAESPAGEVEKSFRVRVQ---APPNVVGP-RGPRSVVGLAPGQLILECSVEAEPAP 2546
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
+ W + G L+ + T F + L + + G YSCTA N GS S + R+
Sbjct: 2547 EIEWHRGGVLLQ--ADAHTHFPEQGRFLKLQALSTADGGDYSCTARNRAGSTSVAFRV-- 2602
Query: 537 TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
E P V+ V + C G V+W KD + G+ ++ +L
Sbjct: 2603 -EIHTAPTIQSGPNTVNVSVNRTTLLPCQTHGVPTPLVSWRKDGIPLHP-GSPRLEFLPE 2660
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE-TVEETEGN 893
+ L I V D G Y C A N G D L + E PP+ S T+
Sbjct: 2661 GS-LRIHPVLAQDAGHYLCLASNSAGSDRKGLDLRVFE---PPAIAPGPSNLTLTAYSPA 2716
Query: 894 SFRLEGRVAGSQPISVAWYKN--NVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
S E R GS V W+K+ +++ +NAL L S D+ + C
Sbjct: 2717 SLPCEAR--GSPKPLVTWWKDGQKLDLRLQQGAYRLLPSNALFLTA--PSPQDSAQFECV 2772
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
VSN+ G + + + PP T TV+ + L+CH GS + W KAG
Sbjct: 2773 VSNEVGESRRRYQVTV---HVPPTIADDQTHFTVTRMAPVILTCHSTGSPTPAVSWSKAG 2829
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
++ R S + LE + AG Y C A N AG +T
Sbjct: 2830 TQL--GARGSGYRILPSGALEIERALPLHAGRYTCTARNSAGVARKHMVLT--------- 2878
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
V P ++VV + G P P V W K + + +G + +
Sbjct: 2879 ------VQASPVVKPLPSVVQVVASEEVLLPCEASGIPQPMVIWQK-EGLSIPEGAHMQV 2931
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
G +L I + D+G Y C+A N G + L V
Sbjct: 2932 LPSG---QLRIMHASPEDAGNYFCIAQNSVGSAMAKTRLVV 2969
Score = 126 bits (316), Expect = 7e-29
Identities = 134/560 (23%), Positives = 221/560 (39%), Gaps = 10/560 (1%)
Frame = +3
Query: 150 LVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVV 323
L + + +G Y C AEN+ E ++V +PP S ++ +
Sbjct: 2110 LQLSHLQPAQAGTYTCVAENAQAEARKDFVVSVL---VPPQIQDSGMAQEHNVLEKQEIR 2166
Query: 324 FECAVSGSEPISVSWFKDGRPLKD--GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATN 497
C G P ++W KDG L GP+++ +LD +TL + + +G Y+C A N
Sbjct: 2167 LHCEAEGQPPPDITWLKDGGLLDQHVGPHLRF-YLDG-STLVLKGLRTADSGAYTCVAHN 2224
Query: 498 PIGSASSSARLILTEGRNPPFFDIPLAPVDAVV---GESADFECHVTGTQPIKVAWAKDN 668
P G ARL PP +V GE C V G+ PI V+W KD
Sbjct: 2225 PAGE---DARLHTVNVLVPPTIKQQAGDTGTLVSRTGELVTMVCPVQGSPPIHVSWLKDG 2281
Query: 669 REIRSGGNYQISYLENSAH-LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPP 845
+ Q + L +S L I +V D+G +TC A + G L + L+PP
Sbjct: 2282 LPLPLS---QRTLLHSSGRTLRISQVQLADSGVFTCVAASPAGVADRNFTLLV---LVPP 2335
Query: 846 SFTK-KLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQ 1022
+ V +G+ L GS V+W K+ + P + L+
Sbjct: 2336 ILEPVEFQNNVMAAQGSEVVLPCEARGSPLPLVSWMKDGEPLLPQS------LEQGPGLK 2389
Query: 1023 VKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP-VTVSEGEFLQLSC 1199
++ S+GDAG Y+C +++AG A + + +P P + + T ++++ G L+L C
Sbjct: 2390 LESVSVGDAGTYSCTAASEAGEARRHFQLTVMDP--PHIEESGETSELSLTPGAHLELLC 2447
Query: 1200 HVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSD 1379
RG P I W K G+ ++ ++ S VL +DV +AG Y C A + AG
Sbjct: 2448 EARGIPPPNITWHKDGQALRRTENDS----QAGRVLRVRDVQVDNAGLYTCLAESPAGEV 2503
Query: 1380 TSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW 1559
+V P+S+ + V +P P ++W
Sbjct: 2504 EKSFRVRVQAPPNVVGPRG-------------PRSVVGLAPGQLILECSVEAEPAPEIEW 2550
Query: 1560 TKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
+G L ++G KL+ T D G Y C A N+ G ++++
Sbjct: 2551 HRGGVL-LQADAHTHFPEQGRFLKLQALSTA--DGGDYSCTARNRAGSTSVAFRVEIHTA 2607
Query: 1740 KKQEKIEGDLRAMLKKTPVL 1799
+ + + +T +L
Sbjct: 2608 PTIQSGPNTVNVSVNRTTLL 2627
Score = 125 bits (315), Expect = 9e-29
Identities = 125/547 (22%), Positives = 192/547 (35%), Gaps = 25/547 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK V S +L+C+ TP +SWYK + P+ +++ L +DSG
Sbjct: 1493 VKTKVNSSLTLECECWATPPPSISWYKDGRPVTPS--HRLSVLGEGRLLQIQPTQVSDSG 1550
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQ---------LRDVQETVGL-------- 314
Y+C A N GE + +Q +PP F + L +E G
Sbjct: 1551 RYLCVATNVAGEDDQDFNVLIQ---VPPMFQKMGDVDAGFEPLPHEEEAQGRVTEYREIV 1607
Query: 315 ---PVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSC 485
P C + P ++W+++G+PL + + L + Q + AG+YSC
Sbjct: 1608 ENNPAYLYCDTNAIPPPELTWYREGQPLSAADGVSVLQGGRILQLPLVQAED--AGRYSC 1665
Query: 486 TATNPIGSASSSARL-ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAK 662
A N +G L +LT P + V + EC G V+W +
Sbjct: 1666 KAANEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPALGNPAPAVSWFQ 1725
Query: 663 DNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP 842
+ + Q+ LE L + + D Y C A N+ G L ++ +P
Sbjct: 1726 NGLPVSPSPRLQV--LEEGQVLKVATAEVADAASYMCVAENQAGSAEKLFTLKVQ---VP 1780
Query: 843 PSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQ 1022
P + + + T +S L V V WYK+ + + E L+
Sbjct: 1781 PQISDWTTSQLTATLNSSVSLPCEVYAHPNPEVTWYKDGQPL--SLGQEAFLLPGTHTLR 1838
Query: 1023 VKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQH----LTPVTVSEGEFLQ 1190
+ +A D+G Y C+ N AG +V PP F Q + V G+
Sbjct: 1839 LARAQPADSGTYLCEALNAAGR---DQKMVQLNVLVPPSFKQAPGGPQEAIQVRAGDKAI 1895
Query: 1191 LSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVA 1370
LSC + W K + + R G LE D +D G Y CK SN A
Sbjct: 1896 LSCETDSLPEPAVTWFKDQQPLALGQR--IQGLQGGQTLEILDSQASDKGVYSCKVSNTA 1953
Query: 1371 GSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPN 1550
G + F E +++ V T V G P P
Sbjct: 1954 GEAIRTFVLAIQVPPT--------------FEKPERETVNQVAGRTLVLACDVSGIPAPT 1999
Query: 1551 VKWTKGK 1571
V W K +
Sbjct: 2000 VTWLKDR 2006
Score = 123 bits (308), Expect = 6e-28
Identities = 140/559 (25%), Positives = 208/559 (37%), Gaps = 69/559 (12%)
Frame = +3
Query: 261 LPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATL 440
+PP R ++ G + C G+ ++WFKDG L G Q S +
Sbjct: 9 VPPQVQPGPRVLKVLAGEALDLNCVAEGNPQPQLNWFKDGMALM-GEGAQGS-------V 60
Query: 441 NIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFF--DIPLAPVDAVVGESADF 614
+ S AG Y C A+N G+ + L++ E PP + D + ++ V GE+A
Sbjct: 61 HFAAVKTSDAGLYRCEASNSAGTDTWKLELLVLE---PPHWGTDETKSLLERVAGENASL 117
Query: 615 ECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVG 794
C GT ++ W + G ++ L+ + L + V D+G+Y C A NEVG
Sbjct: 118 PCPAQGTPKPRITWRRGPSSEPLNGRPDVAVLDEGS-LFLSSVSLADSGEYECQATNEVG 176
Query: 795 KDSCTAQLNIKERLIPPSFTKKLSET-VEETEGNSFRLEGRVAGSQPISVAWYKN----- 956
S A+L + +PPS ++ T V G LE + G VAW K+
Sbjct: 177 SASRRAKLVV---YVPPSIREEGHITNVSGLAGQPLTLECDINGFPAPEVAWLKDGQLVG 233
Query: 957 ------NVEIHP-------------------TANCE------------------------ 989
+ E+ P T C+
Sbjct: 234 DSGGGWDGEVPPSLLGAGAAQEVLGLAGADVTLECQTSGVPTPQVEWTKDGQPILPGDPH 293
Query: 990 ITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT-PVT 1166
I + + +L++ + +GD G Y C V + AG + I P P ++ + T VT
Sbjct: 294 ILLQEDGQVLRIISSHLGDEGQYQCVVFSPAGQQAKDFQLSIHSP--PTIWGSNETGEVT 351
Query: 1167 VSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDY 1346
V EG QL C RG I W K G + PS +S G L+ +DAG Y
Sbjct: 352 VLEGHTAQLLCEARGMPSPAITWYKDGTLLAPSSEVVYS--KGGRQLQLVKAQPSDAGLY 409
Query: 1347 VCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAK 1526
C+ASN AG T KS DG P ++ V
Sbjct: 410 TCQASNPAGI-TKKS-----TSLEVYVPPTIEGADG------GPYLVQAVAGRPVALECV 457
Query: 1527 VGGDPIPNVKW---------TKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRC 1679
G P P + W + G W L GG + + G+ GLY C
Sbjct: 458 ARGHPPPTISWQHEGLPVVDSNGTW--LEAGGALQLENPGE-----------ASGGLYSC 504
Query: 1680 VAFNKHGE--IESNVNLQV 1730
VA + GE ++ +V +QV
Sbjct: 505 VASSPAGEAVLQYSVEMQV 523
Score = 115 bits (287), Expect = 2e-25
Identities = 111/424 (26%), Positives = 161/424 (37%)
Frame = +3
Query: 36 LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSV 215
L C G+P VSW K T+L + + L + +G Y C A NS
Sbjct: 2811 LTCHSTGSPTPAVSWSKAGTQLGARGSGYRILPSGA--LEIERALPLHAGRYTCTARNSA 2868
Query: 216 GEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKD 395
G LTVQ P VQ V+ C SG V W K+G + +
Sbjct: 2869 GVARKHMVLTVQAS---PVVKPLPSVVQVVASEEVLLPCEASGIPQPMVIWQKEGLSIPE 2925
Query: 396 GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPL 575
G ++Q L I AG Y C A N +GSA + RL++ + PP + L
Sbjct: 2926 GAHMQVL---PSGQLRIMHASPEDAGNYFCIAQNSVGSAMAKTRLVV---QVPPVIENGL 2979
Query: 576 APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGD 755
+ + G A C G+ + W KD + SG + + L+ S L + + D
Sbjct: 2980 PDLSTIEGSHALLPCTAKGSPEPAITWEKDGHLV-SGAEGKFT-LQPSGELLVKNSEGQD 3037
Query: 756 TGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPI 935
G Y C A N VG+ L I L P T + G+ L GS
Sbjct: 3038 AGTYICTAENAVGRARRRVHLTI---LTLPVLTTLPGDRSLRL-GDRLWLRCVARGSPTP 3093
Query: 936 SVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVI 1115
+ W N+ + ++ ++ LQ + D+G YTC N G S + +
Sbjct: 3094 RIGWTINDQPVTEG----VSEQDGGSTLQRAAVTREDSGTYTCWAENRVGRVQAVSFVHV 3149
Query: 1116 KEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANG 1295
KE P + + + + G +QL C VRG I W K G + P R F NG
Sbjct: 3150 KEA--PVLQGEAFSYLVEPVGGSIQLHCVVRGDPAPDIHWTKDGLPL-PISRLHFQLQNG 3206
Query: 1296 TAVL 1307
+ +
Sbjct: 3207 SLTI 3210
Score = 112 bits (281), Expect = 8e-25
Identities = 137/580 (23%), Positives = 209/580 (36%), Gaps = 5/580 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V G L C+ G+P VSW K L P + L V D+G
Sbjct: 2346 VMAAQGSEVVLPCEARGSPLPLVSWMKDGEPLLPQSL------EQGPGLKLESVSVGDAG 2399
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C A + GE LTV + PP S + ++ T G + C G P +
Sbjct: 2400 TYSCTAASEAGEARRHFQLTVMD---PPHIEESGETSELSLTPGAHLELLCEARGIPPPN 2456
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W KDG+ L+ N S V + Q D AG Y+C A +P G S R+ +
Sbjct: 2457 ITWHKDGQALRRTEN--DSQAGRVLRVRDVQVDN--AGLYTCLAESPAGEVEKSFRVRV- 2511
Query: 540 EGRNPPFFDIPLAPVDAVVGESAD---FECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
+ PP P P +VVG + EC V ++ W + +++ + +
Sbjct: 2512 --QAPPNVVGPRGP-RSVVGLAPGQLILECSVEAEPAPEIEWHRGGVLLQADAH--THFP 2566
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEG 890
E L + + D G Y+C A N G S ++ I S ++ +V T
Sbjct: 2567 EQGRFLKLQALSTADGGDYSCTARNRAGSTSVAFRVEIHTAPTIQSGPNTVNVSVNRTT- 2625
Query: 891 NSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
L + G V+W K+ + +HP + + F L++ DAG Y C
Sbjct: 2626 ---LLPCQTHGVPTPLVSWRKDGIPLHP-GSPRLEFLPEG-SLRIHPVLAQDAGHYLCLA 2680
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
SN AGS + + E PP + +T++ L C RGS + W K G+
Sbjct: 2681 SNSAGSDRKGLDLRVFE---PPAIAPGPSNLTLTAYSPASLPCEARGSPKPLVTWWKDGQ 2737
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
++ + + L + D+ + C SN G + +VT
Sbjct: 2738 KLDLRLQQGAYRLLPSNALFLTAPSPQDSAQFECVVSNEVGESRRRYQVT---------- 2787
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
V + V G P P V W+K + +G I
Sbjct: 2788 -----VHVPPTIADDQTHFTVTRMAPVILTCHSTGSPTPAVSWSKAGTQLGARGSGYRIL 2842
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
G LEI +G Y C A N G ++ L V
Sbjct: 2843 PSG---ALEIERALPLHAGRYTCTARNSAGVARKHMVLTV 2879
Score = 58.5 bits (140), Expect = 2e-08
Identities = 40/119 (33%), Positives = 59/119 (49%)
Frame = +3
Query: 1035 SMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGS 1214
+M D G Y C N+ G+ ++V++ PVF VTV G ++L C G
Sbjct: 3367 TMDDVGRYQCLAVNEMGTVKKVVTVVLQSA---PVFQVEPRDVTVRSGVDVELRCRATGE 3423
Query: 1215 EPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS 1391
I+WL+AGR ++ + R + +G+ LE V DAG Y C A N GS T+K+
Sbjct: 3424 PVPTIEWLRAGRPLQ-AGRKLRALPDGSLWLE--HVEAGDAGVYECVAHNRLGSVTAKA 3479
Score = 57.0 bits (136), Expect = 5e-08
Identities = 39/124 (31%), Positives = 55/124 (44%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
+GD L+C G+P + W D + T + ++ +TL V DSG Y C
Sbjct: 3077 LGDRLWLRCVARGSPTPRIGWTINDQPV----TEGVSEQDGGSTLQRAAVTREDSGTYTC 3132
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKD 377
AEN VG V + +F+ V+E P + E VG + C V G + W KD
Sbjct: 3133 WAENRVGRVQAVSFVHVKE--APVLQGEAFSYLVEPVGGSIQLHCVVRGDPAPDIHWTKD 3190
Query: 378 GRPL 389
G PL
Sbjct: 3191 GLPL 3194
Score = 55.1 bits (131), Expect = 2e-07
Identities = 35/119 (29%), Positives = 54/119 (45%)
Frame = +3
Query: 174 NDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEP 353
+D G Y C A N +G V + +Q P F + RDV G+ V C +G
Sbjct: 3369 DDVGRYQCLAVNEMGTVKKVVTVVLQSA---PVFQVEPRDVTVRSGVDVELRCRATGEPV 3425
Query: 354 ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
++ W + GRPL+ G ++ +L + + AG Y C A N +GS ++ A L
Sbjct: 3426 PTIEWLRAGRPLQAGRKLRAL---PDGSLWLEHVEAGDAGVYECVAHNRLGSVTAKALL 3481
>ref|NP_954603.2| obscurin isoform 2 [Mus musculus].
Length = 7489
Score = 167 bits (423), Expect = 3e-41
Identities = 159/615 (25%), Positives = 241/615 (39%), Gaps = 11/615 (1%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+ T G A+L+CQ++ T V W KG LR Y + V L + D+GE
Sbjct: 4073 EATEGTMATLRCQMSKTAP--VEWKKGSETLRDGGRYSLRQDGPVCELQICDLAVEDAGE 4130
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y C G+ +S L+++ LPP F LR + T G C +S + P V W
Sbjct: 4131 YSCVC----GQEKTSATLSIKA--LPPRFIEDLRSQEATEGTMATLRCQMSKAAP--VEW 4182
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K L DG V L I G+YSC SA+ + + +
Sbjct: 4183 RKGSETLGDGGRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKAL----- 4237
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP F L +A G A C ++ P++ W K + +R GG Y + L
Sbjct: 4238 -PPRFIEDLRSQEATEGTMATLRCQMSKAAPVE--WRKGSETLRDGGRYSLRQDGAVCEL 4294
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
I +D D GQY+C G++ +A L + +PP FT+ L + E TEG L
Sbjct: 4295 QIHDLDVEDAGQYSCVC----GQEKTSAVLTVDA--LPPKFTEGLKKE-EATEGTMVTL- 4346
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
R S+ +V W K + + LQ+ ++ DAG Y+C + S
Sbjct: 4347 -RCQMSKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTS 4405
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
A + + PP F + L +EG L C + + P+ +W K ++ D
Sbjct: 4406 ATLSVKAL------PPRFIEDLRSQEATEGTMATLRCQMSKAAPV--EWRKGSETLRDGD 4457
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
R S L+ +D+ DAG+Y+C S T K
Sbjct: 4458 RYSLRQDGAVCELQIRDLAVEDAGEYLCVCGQEKTSATLSVKALPPR------------- 4504
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F+ + +S E T AT ++ V+W KG + L G R + Q G
Sbjct: 4505 -----FIEDLRSQEATEGTMATLRCQM--SKAAPVEWRKGS-KTLRDGDRYSLRQDGAMC 4556
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV--------NERKKQEKIEG---DLRA 1775
+L+I D D+G Y CV G+ +++ L V + + QE EG LR
Sbjct: 4557 ELQICDLAVEDTGDYSCVC----GQEKTSATLSVKALPPRFIEDLRSQEAREGTVATLRC 4612
Query: 1776 MLKKTPVLKKGAGEE 1820
+ K ++ G E
Sbjct: 4613 RMSKAAPVEWRKGSE 4627
Score = 160 bits (406), Expect = 3e-39
Identities = 143/557 (25%), Positives = 219/557 (39%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+ T G A+L+CQ++ V W KG LR Y + V L + +D D+G+
Sbjct: 4249 EATEGTMATLRCQMSKAAP--VEWRKGSETLRDGGRYSLRQDGAVCELQIHDLDVEDAGQ 4306
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y C G+ +S LTV LPP F+ L+ + T G V C +S + +V W
Sbjct: 4307 YSCVC----GQEKTSAVLTVDA--LPPKFTEGLKKEEATEGTMVTLRCQMS--KEATVEW 4358
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K + L DG + L I AG+YSC SA+ S + +
Sbjct: 4359 RKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTSATLSVKAL----- 4413
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP F L +A G A C ++ P++ W K + +R G Y + L
Sbjct: 4414 -PPRFIEDLRSQEATEGTMATLRCQMSKAAPVE--WRKGSETLRDGDRYSLRQDGAVCEL 4470
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
I + D G+Y C G++ +A L++K +PP F + L + E TEG L
Sbjct: 4471 QIRDLAVEDAGEYLCVC----GQEKTSATLSVKA--LPPRFIEDL-RSQEATEGTMATLR 4523
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+++ + P+ W K + + + LQ+ ++ D G Y+C + S
Sbjct: 4524 CQMSKAAPVE--WRKGSKTLRDGDRYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTS 4581
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
A + + PP F + L EG L C + + P+ +W K +K D
Sbjct: 4582 ATLSVKAL------PPRFIEDLRSQEAREGTVATLRCRMSKAAPV--EWRKGSETLKDGD 4633
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
R S L+ +D+ D +Y C S T K
Sbjct: 4634 RYSLRQEGNLCELQIRDLAVEDTEEYSCVCGQEKTSATLSVKALPAK------------- 4680
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F+ + +S E +T T K+ +V W KG L G R + Q G
Sbjct: 4681 -----FIEDLRSQEAPESSTVTLRCKLSKKA--SVVWKKGS-ETLRNGARYSLRQDGAVC 4732
Query: 1629 KLEIRDTTKTDSGLYRC 1679
+LEIRD T D+G Y C
Sbjct: 4733 ELEIRDLTVEDTGEYSC 4749
Score = 156 bits (395), Expect = 5e-38
Identities = 144/566 (25%), Positives = 238/566 (42%), Gaps = 6/566 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK G SA+L C++A + V+W+K KL ++ +M LV Q D+G
Sbjct: 1266 VKAEAGASATLSCEVAQA-QTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAG 1324
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR-DVQETVGLPVVFECAVSGSEPISV 362
EY C AE S L V E KL + +Q R +V+ G C V+ ++ V
Sbjct: 1325 EYSCEAEGQ----KLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEVAQAQ-TEV 1379
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+WFKDG+ L ++ L + Q ++ AG+YSC A G S RL + E
Sbjct: 1380 TWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEA----GGQKLSFRLDVAE 1435
Query: 543 GRNPPFFDIPL-APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
+ + + V A G SA C V Q +V W KD +++ S ++ S
Sbjct: 1436 PKLVFAKEQQANSEVKAEAGASATLSCEVAQAQ-TEVTWFKDGKKLSSSSKVRVEASGCS 1494
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L + + K D G+Y+C E G + +L++ E + + ++ V+ G S
Sbjct: 1495 RRLVVQQAGKADAGEYSC----EAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASA 1550
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L VA +Q V W+K+ ++ ++ + + L V++A DAG Y+C +
Sbjct: 1551 TLSCEVAQAQ-TEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSC----E 1605
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
AG + + + EPK +Q + V G LSC V ++ + W K G+++
Sbjct: 1606 AGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQ-TEVTWFKDGKKL 1664
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
S + + + L + KADAG+Y C+A S
Sbjct: 1665 SSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLS------------------FR 1706
Query: 1437 XXXVDGKLFFVSEPQS---IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
+ KL F E Q+ ++ +AT +V V W K ++L+ ++ +
Sbjct: 1707 LDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEV-AQAQTEVTWFK-DGKKLSSSSKVRV 1764
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVA 1685
G +L ++ K D+G Y C A
Sbjct: 1765 EASGCSRRLVVQQAGKADAGEYSCEA 1790
Score = 153 bits (387), Expect = 4e-37
Identities = 148/600 (24%), Positives = 251/600 (41%), Gaps = 10/600 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK G SA+L C++A + V+W+K KL ++ ++ LV Q D+G
Sbjct: 1358 VKAEAGASATLSCEVAQA-QTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAG 1416
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR-DVQETVGLPVVFECAVSGSEPISV 362
EY C A G S L V E KL + +Q +V+ G C V+ ++ V
Sbjct: 1417 EYSCEA----GGQKLSFRLDVAEPKLVFAKEQQANSEVKAEAGASATLSCEVAQAQT-EV 1471
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+WFKDG+ L ++ L + Q ++ AG+YSC A G S RL + E
Sbjct: 1472 TWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEA----GGQKLSFRLDVAE 1527
Query: 543 GRNPPFFDIPL-APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
+ + + V A G SA C V Q +V W KD +++ S ++ S
Sbjct: 1528 PKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQT-EVTWFKDGKKLSSSSKVRVEASGCS 1586
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L + + K D G+Y+C E G + +L++ E + + ++ V+ G S
Sbjct: 1587 RRLVVQQAGKADAGEYSC----EAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASA 1642
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L VA +Q V W+K+ ++ ++ + + L V++A DAG Y+C +
Sbjct: 1643 TLSCEVAQAQT-EVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSC----E 1697
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
AG + + + EPK +Q + V G LSC V ++ + W K G+++
Sbjct: 1698 AGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQT-EVTWFKDGKKL 1756
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
S + + + L + KADAG+Y C+A
Sbjct: 1757 SSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGG------------------QKLFFR 1798
Query: 1437 XXXVDGKLFFVSEPQS---IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
+ KL F E Q+ ++ +AT +V V W K ++L+ ++ +
Sbjct: 1799 LDVAEPKLMFAKEQQAHSEVKAEAGASATLSCEVA-QAQTEVTWFKDG-KKLSSSSKVRV 1856
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK----KQEKIEGDLRA 1775
G +L ++ K D+G Y C A G + + L V E K K+++ +++A
Sbjct: 1857 EASGCSRRLVVQQAGKADAGEYSCEA----GGQKLSFRLDVAEPKLVFAKEQQAHSEVKA 1912
Score = 149 bits (376), Expect = 8e-36
Identities = 150/589 (25%), Positives = 242/589 (41%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+ T G A+L+CQ++ V W KG LR Y + V L + D+GE
Sbjct: 4425 EATEGTMATLRCQMSKAAP--VEWRKGSETLRDGDRYSLRQDGAVCELQIRDLAVEDAGE 4482
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y+C G+ +S L+V+ LPP F LR + T G C +S + P V W
Sbjct: 4483 YLCVC----GQEKTSATLSVKA--LPPRFIEDLRSQEATEGTMATLRCQMSKAAP--VEW 4534
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K + L+DG + L I G YSC SA+ S + +
Sbjct: 4535 RKGSKTLRDGDRYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKAL----- 4589
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP F L +A G A C ++ P++ W K + ++ G Y + N L
Sbjct: 4590 -PPRFIEDLRSQEAREGTVATLRCRMSKAAPVE--WRKGSETLKDGDRYSLRQEGNLCEL 4646
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
I + DT +Y+C G++ +A L++K +P F + L + E E ++ L
Sbjct: 4647 QIRDLAVEDTEEYSCVC----GQEKTSATLSVKA--LPAKFIEDL-RSQEAPESSTVTLR 4699
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
++ S+ SV W K + + A + L+++ ++ D G Y+C + S
Sbjct: 4700 CKL--SKKASVVWKKGSETLRNGARYSLRQDGAVCELEIRDLTVEDTGEYSCTCGQERTS 4757
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
A T SI+ + VF Q L + EG L C + + W K G E++
Sbjct: 4758 A--TLSIMAPQV----VFQQPLQNLQAEEGSMASLRCELSVPNAAMV-WSKGGLELQGDT 4810
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
R A L +D+ + DAG+Y C GS T+ + +
Sbjct: 4811 RREARQQGCVAELLLRDLRREDAGEYSC----TCGSQTTSATLMVTA------------- 4853
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
+ F+ E Q+ V E TA ++ + + +V+W KG QL + + Q+G A
Sbjct: 4854 -APVRFLRELQAQDVDEGATARLRCELSREAV-SVEWRKGSL-QLFPCAKYQMVQEGTTA 4910
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRA 1775
+L + + D+G Y C A G +S L V R + K + DL++
Sbjct: 4911 ELLVHGVEQEDAGEYTCDA----GHTQSIARLSV--RAPKPKFKTDLQS 4953
Score = 143 bits (360), Expect = 6e-34
Identities = 115/416 (27%), Positives = 174/416 (41%), Gaps = 40/416 (9%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V+VG A+L CQ+ G P VSW K + A +++ +V L + DSG+Y
Sbjct: 20 VSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGDSGQY 79
Query: 192 ICRAENSVGEVSSSTFLTVQEQ----KLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
+CRA N++GE ++ L V + + P F + ++ G F C V GS +
Sbjct: 80 VCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATFRCRVGGSPQPA 139
Query: 360 VSWFKDGRPL--KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
VSW KDGR L D P+++ + L I G Y A NP+GSAS++A L+
Sbjct: 140 VSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALV 199
Query: 534 L---TEGRNPPFFD-------------------IPLAPVDA-------VVGESADFECHV 626
+ E PP IP +P A G+ A C V
Sbjct: 200 VDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFV 259
Query: 627 TGTQPIKVAWAKDNREIRSGGNYQISYLENSAH-LTILKVDKGDTGQYTCYAVNEVGKDS 803
TG + W KD + + G + + E L IL + D G YTC A N VG+
Sbjct: 260 TGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNLVGQTY 319
Query: 804 CTAQLNIKERLIPPSFTKKLSE-TVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTA 980
+ + ++E +P F K+L + V E E +F+ E AW+K + +A
Sbjct: 320 SSVLVVVREPTVP--FKKRLQDLEVREKESATFQCE---VAQPATEAAWFKEETRLWASA 374
Query: 981 NCEITFKNNALLLQVKKASMGDAGLYTCKV---SNDAGSALCTSSIVIKEPKKPPV 1139
+I + L V+ S D +Y C+ S ++ K P+K V
Sbjct: 375 KYDIEEEGTERRLTVRNVSADDDAVYICETTEGSRTVAELSVQGNLTRKLPRKTAV 430
Score = 138 bits (348), Expect = 1e-32
Identities = 150/615 (24%), Positives = 236/615 (38%), Gaps = 11/615 (1%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+ T G + +L+C+L T E V W KG LR Y + V L + D+GE
Sbjct: 3649 EATEGTTVTLRCEL--TKEAPVEWKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGE 3706
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y C G+ +S LTV+ L F R+LR + T G +C +S + P V W
Sbjct: 3707 YSCVC----GQEKTSATLTVKA--LLVHFVRRLRSKEATEGDTTTLQCELSKAAP--VEW 3758
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K L+DG V L I + AG+Y CT SA+ + R +
Sbjct: 3759 RKGTETLRDGDRYSLKQDGAVCELQIRSLTIADAGEYLCTCGQEKTSATLTVRAL----- 3813
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
P F L +A G +A C ++ P V W K + ++SG Y + L
Sbjct: 3814 -PAKFKDSLKNEEATEGTTATLSCELSKAAP--VTWKKGPKTLQSGDKYVLRQDGAVCGL 3870
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
I + D G+Y+C G++ +A L + R +P F + L + E TEG + L
Sbjct: 3871 QIHGLTMADAGEYSCVC----GQEKTSATLTV--RGLPAKFIEDL-RSQEATEGATAILR 3923
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
++ + P+ W K + + + LQ++ ++ D G Y+
Sbjct: 3924 CELSKAAPVE--WRKGSETLKDGDRYTLRQDGAVCELQIRGLAVVDTGTYSL-------- 3973
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
P F + L +EG L C + + P+ +W K ++ D
Sbjct: 3974 --------------PTKFTEGLRNEEATEGTMATLRCQMSKAAPV--EWRKGSETLRDGD 4017
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
R S L+ + +T D+G+Y C S T K
Sbjct: 4018 RYSLRQDGAMCELQIRGLTIEDSGEYTCVCGQEKTSATLSVKALPSR------------- 4064
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F+ + +S E T AT ++ V+W KG L GGR + Q G
Sbjct: 4065 -----FIEDLRSQEATEGTMATLRCQM--SKTAPVEWKKGS-ETLRDGGRYSLRQDGPVC 4116
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ--------VNERKKQEKIEG---DLRA 1775
+L+I D D+G Y CV G+ +++ L + + + QE EG LR
Sbjct: 4117 ELQICDLAVEDAGEYSCVC----GQEKTSATLSIKALPPRFIEDLRSQEATEGTMATLRC 4172
Query: 1776 MLKKTPVLKKGAGEE 1820
+ K ++ G E
Sbjct: 4173 QMSKAAPVEWRKGSE 4187
Score = 136 bits (342), Expect = 7e-32
Identities = 139/563 (24%), Positives = 239/563 (42%), Gaps = 5/563 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAG-TPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
V+V G+S S +C L+ +P W G + + + + TL +D+
Sbjct: 3110 VEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDA 3169
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GE + SV ++S L ++E+ P ++ L D + T+G V+ C +S + SV
Sbjct: 3170 GEVVF----SVLGLTSKASLIIRER--PVDITKPLEDQRTTLGEDVMLSCELSRAGT-SV 3222
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W KDG+ ++ A L + + +G+Y+C ++ S+A+L + E
Sbjct: 3223 RWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCETE----ASKSTAKLCVEE 3278
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
N F LA + A F C + V W K E+R+ G + S +
Sbjct: 3279 KANR--FTEELADLQVEEKGRAVFTCKTEHPASV-VTWRKGLLELRASGKHVPSQEGLTL 3335
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET---EGN 893
LTI +++ D+ YTC ++G+ A+L + + + ++ E +E+T EG+
Sbjct: 3336 KLTINALERTDSDTYTC----DIGQARTQARLLVHGQKV------RVIEDLEDTAVQEGS 3385
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNAL-LLQVKKASMGDAGLYTCKV 1070
S + R+A + V W+ + +H EIT + +L +++ ++ D+G V
Sbjct: 3386 SAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGT----V 3441
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
+AG ++++ + E KP +F + LT VTV+EGE L L C + ++W K G+
Sbjct: 3442 YFEAGDQRTSAALRVTE--KPSIFSRPLTDVTVTEGEDLTLVCETTTVDS-SVRWTKDGK 3498
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
++PS RC S A L T D G Y C+ + S +
Sbjct: 3499 TLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHAL---------- 3548
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
+ F + + V E AT + P V+W G L + +
Sbjct: 3549 --------PVRFRESLKDVEVPEGKAATLRCVLSSVAAP-VEWRHGD-DVLKSSNKYSLR 3598
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRC 1679
Q+G +L IRD DSG Y C
Sbjct: 3599 QEGAVLELVIRDLQPQDSGQYSC 3621
Score = 135 bits (341), Expect = 9e-32
Identities = 137/580 (23%), Positives = 241/580 (41%), Gaps = 12/580 (2%)
Frame = +3
Query: 72 VSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQ 251
V+W K +L Y+M L+ V +D+G Y C + S ++ L VQ
Sbjct: 735 VTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGS----RTAYQLLVQ 790
Query: 252 EQKLPPSFSRQLR-DVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDN 428
E KL + +Q +V+ G C V+ ++ V+WFKDG+ L ++
Sbjct: 791 EPKLVFAKGQQAHSEVKAEAGNSATLSCEVTQAQT-EVTWFKDGKKLSSSSKVRMEASGC 849
Query: 429 VATLNIFQTDRSFAGQYSCTATNPIGSAS---SSARLILTEGRNPPFFDIPLAPVDAVVG 599
L + Q ++ AG+YSC A S + +L+ +G+ + V A G
Sbjct: 850 SRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKGQQAH------SEVKAEAG 903
Query: 600 ESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYA 779
SA C V Q +V W KD +++ S ++ S L + + K D G+Y+C
Sbjct: 904 ASATLSCEVAQAQ-TEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSC-- 960
Query: 780 VNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNN 959
E G + +L++ E + + ++ V+ G S L VA +Q V W+K+
Sbjct: 961 --EAGGQKLSFRLDVAEPKMVFAKEQQARSEVKAEAGASATLSCEVAQAQ-TEVTWFKDG 1017
Query: 960 VEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPV 1139
++ ++ + + L V++A DAG Y+C +AG + + + EPK
Sbjct: 1018 KKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSC----EAGGQKLSFRLDVTEPKLVFA 1073
Query: 1140 FDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFK 1316
+Q + V G LSC V ++ + W K G+++ S + + + L +
Sbjct: 1074 KEQQARSEVKAEVGNSATLSCEVAQAQ-TEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQ 1132
Query: 1317 DVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS---I 1487
KADAG+Y C+A S + KL F E Q+ +
Sbjct: 1133 QAGKADAGEYSCEAGGQKLS------------------FRLDVAEPKLVFAKEQQARSEV 1174
Query: 1488 RVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSG 1667
+ +AT +V V W K ++L+ ++ + G +L ++ K D+G
Sbjct: 1175 KAEAGNSATLSCEV-AQAQTEVTWFK-DGKKLSSSSKVRMEASGCSRRLVVQQAGKADAG 1232
Query: 1668 LYRCVAFNKHGEIESNVNLQVNERK----KQEKIEGDLRA 1775
Y C A G + + +L V E K K+++ +++A
Sbjct: 1233 EYSCEA----GGQKLSFHLDVTEPKLVFAKEQQAHSEVKA 1268
Score = 135 bits (340), Expect = 1e-31
Identities = 145/552 (26%), Positives = 231/552 (41%), Gaps = 1/552 (0%)
Frame = +3
Query: 27 SASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAE 206
S L C P+ V WYK DT L P+ +KM +A L ++ D+G Y C+A
Sbjct: 2850 SVVLSCDFRPAPK-AVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQA- 2907
Query: 207 NSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRP 386
G SS +TV+ +++ + + L+D + V F C +S + + W +G P
Sbjct: 2908 ---GSAQSSAEVTVEAREV--TVIQPLQDAEAMEEGRVCFSCELSHKDE-DIEWSLNGTP 2961
Query: 387 LKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFD 566
L + + S + TL + ++ G + AT+P S SARL++ +G+ P F
Sbjct: 2962 LYNDSFHEISHEGCLHTLVLKSVRQADTG--TVCATSP--KVSVSARLVV-KGK-PVVFL 3015
Query: 567 IPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVD 746
L V A + +C V+ + +V W KD E+ Y + + LT+ +
Sbjct: 3016 KALDDVSAEERGTLTLQCEVSDPE-ARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLS 3074
Query: 747 KGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGS 926
D G YTC +VG +++++ + + TK+L +TVE EG S E ++
Sbjct: 3075 HEDAGLYTC----QVGSKETQSKVSVHD--LHVGITKRL-KTVEVLEGESCSFECVLSHE 3127
Query: 927 QPISVA-WYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTS 1103
P A W + + + + L VK A++ DAG V A
Sbjct: 3128 SPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKA---- 3183
Query: 1104 SIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFS 1283
S++I+E +P + L + GE + LSC + ++WLK G+ I+ S +
Sbjct: 3184 SLIIRE--RPVDITKPLEDQRTTLGEDVMLSCEL-SRAGTSVRWLKDGKAIRKSQKYDLL 3240
Query: 1284 FANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLF 1463
AVL + + D+G+Y C+ A T+K V
Sbjct: 3241 SEGTRAVLVVRKASLKDSGEYTCETE--ASKSTAKLCVEEKANR---------------- 3282
Query: 1464 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIR 1643
F E ++V EK A F K P V W KG +L G+ Q+G KL I
Sbjct: 3283 FTEELADLQVEEKGRAVFTCKT-EHPASVVTWRKG-LLELRASGKHVPSQEGLTLKLTIN 3340
Query: 1644 DTTKTDSGLYRC 1679
+TDS Y C
Sbjct: 3341 ALERTDSDTYTC 3352
Score = 134 bits (338), Expect = 2e-31
Identities = 139/576 (24%), Positives = 233/576 (40%), Gaps = 2/576 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK G SA+L C++A + V+W+K KL ++ ++ LV QV D+G
Sbjct: 1910 VKAEAGASATLSCEVAQA-QTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQVGKADAG 1968
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR-DVQETVGLPVVFECAVSGSEPISV 362
EY C A S L V + +L + +Q R +V+ G C V+ ++ V
Sbjct: 1969 EYSCEARGQ----KLSFRLDVADTRLMFAKEQQARTEVKAEAGNSATLSCEVAQAQT-EV 2023
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+WFKDG+ L ++ L + Q ++ AG+YSC A G S RL + E
Sbjct: 2024 TWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEA----GGQKLSFRLDVAE 2079
Query: 543 GRNP-PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
+ P P+ E+ + V W KD EIR ++ + L ++
Sbjct: 2080 AESQIPERPSRREPLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDT 2139
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
LT+ D+ Y+C VGK+ + ++E + F+K L E VE G +
Sbjct: 2140 HTLTVRGAQVLDSAIYSC----RVGKEGQDFPVQVEE--VAAKFSKPL-EPVEGELGGTV 2192
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L ++ Q V W N ++ P ++T + L V DA Y C+ +D
Sbjct: 2193 MLVCELSPEQA-EVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDD 2251
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
SA T +K P+ F L+ + EG+ C V S+ + W K G +++
Sbjct: 2252 RTSARLT----VKVPRVVK-FTSGLSAMVAEEGQEATFQCVVSPSDA-GVTWYKDGMQLQ 2305
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
PS++ + + L +T DAG +A + S + +
Sbjct: 2306 PSEKFVMVESGASRSLTILGLTLEDAGQVTVEAEGASSSAALRVR--------------- 2350
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
+ + F + + V E+T+ T ++ P P VKWT+ L + I +G
Sbjct: 2351 ---EAPVLFKKKLEPQTVEERTSVTLEVEL-TRPWPEVKWTRNA-AVLTPSENVEIRAEG 2405
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
L +R D G + C + + + NV ++
Sbjct: 2406 ARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMR 2441
Score = 134 bits (338), Expect = 2e-31
Identities = 155/615 (25%), Positives = 233/615 (37%), Gaps = 12/615 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFR-NNVATLVFNQVDSNDSGE 188
V G SA C++A V W+ T L ++ + L Q+ DSG
Sbjct: 3381 VQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGT 3440
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
A G+ +S L V E+ P FSR L DV T G + C + + SV W
Sbjct: 3441 VYFEA----GDQRTSAALRVTEK--PSIFSRPLTDVTVTEGEDLTLVCETTTVDS-SVRW 3493
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
KDG+ L+ Q S A L I T G+Y C IG ASSS+ I+
Sbjct: 3494 TKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCE----IGGASSSS--IVRVHA 3547
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
P F L V+ G++A C V + V W + ++S Y + L
Sbjct: 3548 LPVRFRESLKDVEVPEGKAATLRC-VLSSVAAPVEWRHGDDVLKSSNKYSLRQEGAVLEL 3606
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
I + D+GQY+C G + +A L +K F KL E TEG + L
Sbjct: 3607 VIRDLQPQDSGQYSC----SFGDQTTSATLTVKTS--SAQFVGKLRNK-EATEGTTVTLR 3659
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+ P+ W K + + LQ+ + DAG Y+C + S
Sbjct: 3660 CELTKEAPVE--WKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCGQEKTS 3717
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
A T ++ F + L +EG+ L C + + P+ +W K ++ D
Sbjct: 3718 ATLTVKALLVH------FVRRLRSKEATEGDTTTLQCELSKAAPV--EWRKGTETLRDGD 3769
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
R S L+ + +T ADAG+Y+C G + + + +T
Sbjct: 3770 RYSLKQDGAVCELQIRSLTIADAGEYLC----TCGQEKTSATLTVRALPAK--------- 3816
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F ++ E TTAT ++ V W KG + L G + + Q G
Sbjct: 3817 -----FKDSLKNEEATEGTTATLSCEL--SKAAPVTWKKGP-KTLQSGDKYVLRQDGAVC 3868
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV--------NERKKQEKIEGD---LRA 1775
L+I T D+G Y CV G+ +++ L V + + QE EG LR
Sbjct: 3869 GLQIHGLTMADAGEYSCVC----GQEKTSATLTVRGLPAKFIEDLRSQEATEGATAILRC 3924
Query: 1776 MLKKTPVLKKGAGEE 1820
L K ++ G E
Sbjct: 3925 ELSKAAPVEWRKGSE 3939
Score = 133 bits (335), Expect = 4e-31
Identities = 136/560 (24%), Positives = 225/560 (40%), Gaps = 6/560 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK G SA+L C++A + V+W+K KL ++ ++ LV Q D+G
Sbjct: 1818 VKAEAGASATLSCEVAQA-QTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAG 1876
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR-DVQETVGLPVVFECAVSGSEPISV 362
EY C A G S L V E KL + +Q +V+ G C V+ ++ V
Sbjct: 1877 EYSCEA----GGQKLSFRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQT-EV 1931
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS---SSARLI 533
+WFKDG+ L ++ L + Q ++ AG+YSC A S + RL+
Sbjct: 1932 TWFKDGKKLSSSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKLSFRLDVADTRLM 1991
Query: 534 LTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
+ + V A G SA C V Q +V W KD +++ S ++
Sbjct: 1992 FAKEQQAR------TEVKAEAGNSATLSCEVAQAQT-EVTWFKDGKKLSSSSKVRVEASG 2044
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKER--LIPPSFTKKLSETVEETE 887
S L + + K D G+Y+C E G + +L++ E IP +++ V+E E
Sbjct: 2045 CSRRLVVQQAGKADAGEYSC----EAGGQKLSFRLDVAEAESQIPERPSRREPLVVKEHE 2100
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
+ L +A +V W K+ VEI + E T + L V+ A + D+ +Y+C+
Sbjct: 2101 --TIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDSAIYSCR 2158
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
V + ++ + F + L PV G + L C + E + W
Sbjct: 2159 VGKEG------QDFPVQVEEVAAKFSKPLEPVEGELGGTVMLVCEL-SPEQAEVVWRCGN 2211
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
+++P R + L + + DA +YVC++ + D + +++T
Sbjct: 2212 TQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRD----DRTSARLT--------- 2258
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
V + F S ++ E ATF V V W K QL + +
Sbjct: 2259 ----VKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSD-AGVTWYK-DGMQLQPSEKFVM 2312
Query: 1608 HQKGDEAKLEIRDTTKTDSG 1667
+ G L I T D+G
Sbjct: 2313 VESGASRSLTILGLTLEDAG 2332
Score = 124 bits (312), Expect = 2e-28
Identities = 144/574 (25%), Positives = 232/574 (40%), Gaps = 6/574 (1%)
Frame = +3
Query: 36 LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSV 215
L+CQ++ V W+KG +L+ Y++ LV N V D Y C A
Sbjct: 2674 LECQVSRA-SAQVRWFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDA---- 2728
Query: 216 GEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKD 395
G V +S V+EQ + + R L+D+ P FEC S W L+
Sbjct: 2729 GNVKTSAQFFVEEQSI--TIVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQA 2786
Query: 396 GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPL 575
G N+ V L + +T + G T IG + SSA+L++++ P PL
Sbjct: 2787 GGNVGLEQDGTVHRLTLHKTCSTMTGPVHFT----IGKSRSSAQLVVSD--IPVVLTRPL 2840
Query: 576 APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGD 755
P +S C P V W KD+ + ++++ A L IL++ D
Sbjct: 2841 EPKAGRELQSVVLSCDFR-PAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPAD 2899
Query: 756 TGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPI 935
G Y C A G +A++ ++ R + + +E +E EGRV S +
Sbjct: 2900 AGVYRCQA----GSAQSSAEVTVEAREVTVIQPLQDAEAME---------EGRVCFSCEL 2946
Query: 936 S-----VAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
S + W N ++ + EI+ + L +K D G C S +
Sbjct: 2947 SHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSVRQADTGT-VCATSPKVS---VS 3002
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSF 1280
+ +V+K KP VF + L V+ E L L C V E R+ W K G E+ PSD+ F
Sbjct: 3003 ARLVVK--GKPVVFLKALDDVSAEERGTLTLQCEVSDPE-ARVVWRKDGVELGPSDKYDF 3059
Query: 1281 SFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKL 1460
G L D++ DAG Y C+ GS ++SKV+ D +
Sbjct: 3060 LHKAGARGLTVHDLSHEDAGLYTCQ----VGSKETQSKVSVH--------------DLHV 3101
Query: 1461 FFVSEPQSIRVVEKTTATFIAKVGGD-PIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
+++ V+E + +F + + P WT G + + G ++G + L
Sbjct: 3102 GITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVG-GKTVGGSGHFHAVRQGRKYTLT 3160
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
++D +D+G V F+ G + S +L + ER
Sbjct: 3161 VKDAALSDAGE---VVFSVLG-LTSKASLIIRER 3190
Score = 120 bits (300), Expect = 5e-27
Identities = 132/561 (23%), Positives = 220/561 (39%), Gaps = 3/561 (0%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+ T G A+L+CQ++ V W KG LR Y + + L + D+G+
Sbjct: 4513 EATEGTMATLRCQMSKAAP--VEWRKGSKTLRDGDRYSLRQDGAMCELQICDLAVEDTGD 4570
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y C G+ +S L+V+ LPP F LR + G C +S + P V W
Sbjct: 4571 YSCVC----GQEKTSATLSVKA--LPPRFIEDLRSQEAREGTVATLRCRMSKAAP--VEW 4622
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K LKDG N+ L I +YSC SA+ S + +
Sbjct: 4623 RKGSETLKDGDRYSLRQEGNLCELQIRDLAVEDTEEYSCVCGQEKTSATLSVKAL----- 4677
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
P F L +A + C ++ + V W K + +R+G Y + L
Sbjct: 4678 -PAKFIEDLRSQEAPESSTVTLRCKLS--KKASVVWKKGSETLRNGARYSLRQDGAVCEL 4734
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN--SFR 902
I + DTG+Y+C G++ +A L+I + P ++ + ++ EG+ S R
Sbjct: 4735 EIRDLTVEDTGEYSCTC----GQERTSATLSI---MAPQVVFQQPLQNLQAEEGSMASLR 4787
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
E V + ++ W K +E+ E + L ++ DAG Y+C +
Sbjct: 4788 CELSVPNA---AMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQ- 4843
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
T+S + P F + L V EG +L C + E + ++W K ++ P
Sbjct: 4844 -----TTSATLMVTAAPVRFLRELQAQDVDEGATARLRCEL-SREAVSVEWRKGSLQLFP 4897
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ TA L V + DAG+Y C AG S ++++
Sbjct: 4898 CAKYQMVQEGTTAELLVHGVEQEDAGEYTCD----AGHTQSIARLSVRAP---------- 4943
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVG-GDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
K F ++ QS TA ++ +P V+W K + +L+ G + + ++G
Sbjct: 4944 ----KPKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQWLK-EGVELHVGSKYEMRRQG 4998
Query: 1620 DEAKLEIRDTTKTDSGLYRCV 1682
+L I D+G Y C+
Sbjct: 4999 AVCELLIHGLEAKDTGEYACL 5019
Score = 110 bits (276), Expect = 3e-24
Identities = 103/415 (24%), Positives = 161/415 (38%), Gaps = 39/415 (9%)
Frame = +3
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
P F P A V +V G+ A C + G V+W KD + + +G ++++ + LT
Sbjct: 9 PRFLTRPKAFVVSV-GKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLT 67
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKER-----LIPPSFTKKLSETVEETEGNS 896
IL + GD+GQY C A N +G+ L + P + S V E +
Sbjct: 68 ILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADAT 127
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHP--TANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
FR RV GS +V+W K+ + P + + + L+++ A D G Y +
Sbjct: 128 FRC--RVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRA 185
Query: 1071 SNDAGSALCTSSIVIKE-------------------------------PKKPPVFDQHLT 1157
N GSA +++V+ P PP
Sbjct: 186 ENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPP--GAGTR 243
Query: 1158 PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR-CSFSFANGTAVLEFKDVTKAD 1334
TV+EG+ +LSC V G W K G+ + R + VL+ ++D
Sbjct: 244 TCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSD 303
Query: 1335 AGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTAT 1514
G Y C ASN+ G S V + + F Q + V EK +AT
Sbjct: 304 RGLYTCTASNLVGQTYSSVLVVVR--------------EPTVPFKKRLQDLEVREKESAT 349
Query: 1515 FIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRC 1679
F +V P W K + R L + I ++G E +L +R+ + D +Y C
Sbjct: 350 FQCEV-AQPATEAAWFKEETR-LWASAKYDIEEEGTERRLTVRNVSADDDAVYIC 402
Score = 104 bits (260), Expect = 2e-22
Identities = 116/494 (23%), Positives = 191/494 (38%), Gaps = 40/494 (8%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRP--TATYKMHFRNNVATLVFNQVDSND 179
++V G A+ +C++ G+P+ VSW K +L P ++ + L D
Sbjct: 118 IRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRD 177
Query: 180 SGEYICRAENSVGEVSSSTFLTVQ---EQKLPPSFS--------RQLRDVQETVGLP--- 317
G Y RAEN +G S++ L V E PP S +Q R+ G+P
Sbjct: 178 GGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSP 237
Query: 318 ---------------VVFECAVSGSEPISVSWFKDGRPLKDGPN--IQTSFLDNVATLNI 446
C V+G W KDG+ + +G + +N L I
Sbjct: 238 PGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENF-VLKI 296
Query: 447 FQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHV 626V + + ++ T G + EC V G
Sbjct: 2265 DAGLYTCVASNVAGTAKKDYGLQVYIRPTISNSGNHPTEIIVTRGKSISLECEVQGIPQP 2324
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
V+W KDGRPL G ++ LD L + S G+Y C A N G L +
Sbjct: 2325 KVTWMKDGRPLTKGRGME--ILDEGRILQLKNIHISDTGRYVCVAVNVAGMTDRKYDLSV 2382
Query: 537 TEGRNPPFF----DIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
PP IP + V S C +G + W KD + + +I
Sbjct: 2383 ---HTPPSIIGNHGIP-ENISVVEKNSVSLTCEASGIPLPSITWLKDGWPVSLSSSVRI- 2437
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKLSETVEE 881
L L +++ D GQYTC N G++ L++ L+PP + E V+
Sbjct: 2438 -LSGGRTLRLMQTRLEDAGQYTCVVRNAAGEERKIFGLSV---LVPPRIVGENTLEDVKV 2493
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
E S L V G+ + W+K+ + I + L++ A + G Y
Sbjct: 2494 KEKQSVTLTCEVTGNPVPEITWHKDGQLLQEDDTHHI--MSGGHFLKITNAQVSHTGRYA 2551
Query: 1062 CKVSNDAGSALCTSSI-VIKEPKKPPV-FDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQW 1235
C SN AG + S+ V+ P V D VTV L C P I W
Sbjct: 2552 CLASNTAGDKSKSFSLNVLVSPTIAGVDSDSGPEDVTVILNSPTSLVCEAYSYPPATITW 2611
Query: 1236 LKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXX 1415
K G ++ S+R + G L+ + + +AG Y C A+N AG +V
Sbjct: 2612 FKDGTPLE-SNR-NIRILPGGRTLQILNAQEDNAGRYSCIATNEAGEMIKHYEVKVYIPP 2669
Query: 1416 XXXXXXXXXXVDGKLFFVS-EPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQG 1592
G L P+ +++ T T + P ++ W K + L
Sbjct: 2670 IIN--------KGDLLGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK-DGQPLKSD 2720
Query: 1593 GRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG--EIESNVNLQV 1730
+ I G L+I++ +D+G Y CVA N G E++ +VN+QV
Sbjct: 2721 DHVNIAASGH--TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQV 2766
Score = 138 bits (348), Expect = 2e-32
Identities = 148/613 (24%), Positives = 243/613 (39%), Gaps = 8/613 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G+ A L C + + ++W + D R +M N ++L V ND+G
Sbjct: 531 VTVLPGERAILTCLVISAVDYNLTWQRNDRDARLADPARMRSLAN-SSLELRTVKFNDAG 589
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY C N G ++S FLTVQE PP + ++ T G V C+ +G ++
Sbjct: 590 EYQCVVSNEGGSSAASVFLTVQE---PPKVTVMPKNQSFTGGSEVSIRCSATGYPKPKIT 646
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W + + + + + TL I AG Y C A+N G+ ++ L E
Sbjct: 647 WTINDMFIMGSHRYR---MTSEGTLFIKNAIPKDAGIYGCLASNSAGTDKQTSTLRYIEA 703
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P + + + +G++ EC +GT +V W K + E+R +L
Sbjct: 704 ---PKLVVVQSELLVALGDTTVMECKSSGTPLPQVKWFKGDLELRPS-----PFLIIDPL 755
Query: 726 LTILKVDKG---DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
L +LK+ + D G YTC AVN+ G+ + L++ PP F ++ ++ E G++
Sbjct: 756 LGLLKIQETQDLDAGDYTCVAVNDAGRAAGKITLDVGS---PPVFIQEPADVSVEI-GSN 811
Query: 897 FRLEGRVAGSQPISVAWYKNN---VEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
L V G + W +++ + P + I+ L + D G Y C+
Sbjct: 812 VTLPCYVQGYPEPKIKWRRSDNMPIFSRPFSVSSISQLRTGALF-ISNLWANDKGTYICE 870
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI-RIQWLKA 1244
N G +++ + P+ + +V EG+ L L C + PI +W+K
Sbjct: 871 AENQFGKIQSQTTVTV-TGLVAPLIGISPSVTSVIEGQQLTLPCALLAGNPIPERRWIKN 929
Query: 1245 GREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXX 1424
+ + + L + V D G Y C ASNVAG+ + V
Sbjct: 930 SAMLVQN---PYITVRSDGSLHIERVRLQDGGKYTCVASNVAGTVNKTTTVDVHVLPTIQ 986
Query: 1425 XXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIF 1604
Q + +E T K G P P++ W+K K ++ F
Sbjct: 987 HG---------------QQVLSTIEGIPVTLPCKASGIPKPSIIWSK-KGELISTSSAKF 1030
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLK 1784
G + L + +SG Y C A N G + V L V R ++ GD R + +
Sbjct: 1031 --SAGADGSLYVASPGGEESGEYVCTATNAAGYAKRKVQLTVYVR---PRVFGDQRGLSQ 1085
Query: 1785 KTPV-LKKGAGEE 1820
PV + AGEE
Sbjct: 1086 DKPVEISVLAGEE 1098
Score = 133 bits (334), Expect = 7e-31
Identities = 142/587 (24%), Positives = 230/587 (39%), Gaps = 11/587 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVAT--LVFNQVDSND 179
V V +G + +L C + G PE + W + D + + + + + T L + + +ND
Sbjct: 804 VSVEIGSNVTLPCYVQGYPEPKIKWRRSDNMPIFSRPFSVSSISQLRTGALFISNLWAND 863
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPP-SFSRQLRDVQETVGLPVVFECAVSGSEPI 356
G YIC AEN G++ S T +TV P S + V E G + CA+ PI
Sbjct: 864 KGTYICEAENQFGKIQSQTTVTVTGLVAPLIGISPSVTSVIE--GQQLTLPCALLAGNPI 921
Query: 357 SVS-WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
W K+ L P I + +L+I + G+Y+C A+N G+ + + +
Sbjct: 922 PERRWIKNSAMLVQNPYITVR---SDGSLHIERVRLQDGGKYTCVASNVAGTVNKTTTV- 977
Query: 534 LTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
+ P + + G C +G + W+K I + + +
Sbjct: 978 --DVHVLPTIQHGQQVLSTIEGIPVTLPCKASGIPKPSIIWSKKGELISTSSAKFSAGAD 1035
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET----VEE 881
S L + ++G+Y C A N G QL + R + LS+ +
Sbjct: 1036 GS--LYVASPGGEESGEYVCTATNAAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISV 1093
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
G L V P + W K I P + + ++ ++ + + D+G+Y
Sbjct: 1094 LAGEEVTLPCEVKSIPPPIITWAKETQLISPFSPRHTFLPSGSM--KIIETRISDSGMYL 1151
Query: 1062 CKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLK 1241
C +N AG+ T S+ + PP + + V G+ + + C +G I W K
Sbjct: 1152 CVATNIAGNV--TQSVKLNV-HVPPKIQRGPKLMKVQVGQRVDIPCTAQGMPLPVITWFK 1208
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
G + S ++GT L +DAG Y C A+N+AGSD ++++T
Sbjct: 1209 GGSAMLVDGVQHISNSDGT--LSIDQAMLSDAGIYTCVATNIAGSD--ETEITLHVQEPP 1264
Query: 1422 XXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR- 1598
+ P RV + A F G P P +KW W GR
Sbjct: 1265 TLEDLEPPYN-------TPFQERVANQRIA-FPCPAKGTPKPTIKWI---WNGRELTGRE 1313
Query: 1599 --IFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
I I + G L I T D+G Y CVA N+ G E NL+V+
Sbjct: 1314 PGISILEDG--TLLVIASVTPYDNGEYICVAVNEAGTTEKKYNLKVH 1358
Score = 133 bits (334), Expect = 7e-31
Identities = 148/586 (25%), Positives = 221/586 (37%), Gaps = 11/586 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ V V + L C +G P ++W K L T + V L QV+ D+G
Sbjct: 3540 ISVIVNNPLELTCLASGIPTPKITWMKDGRPLPQTDQIQTLGGGEVLRLSSAQVE--DTG 3597
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV--GLPVVFECAVSGSEPIS 359
Y C A ++ G+ + V PP+ + TV V EC P
Sbjct: 3598 RYTCLASSTAGDDDKEYLVRVHA---PPNIAGMDESQDFTVLRNRQVTLECKSDAVPPPV 3654
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W K+G L+ P ++ L L + D + Y+C A+N G ++ ILT
Sbjct: 3655 ITWLKNGERLQATPRVR--ILSGGRYLQVNNADLNDTANYTCVASNIAG--KTTREFILT 3710
Query: 540 EGRNPPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
P +I P V+ SA EC G ++ W KD + S + + S LE
Sbjct: 3711 VNVPP---NIKSGPQSVVIHLNMSAVLECLAEGVPAPRITWRKDG-AVLSASHARYSILE 3766
Query: 714 N------SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET- 872
N SAH+T DTG+Y C A N G D L + +PPS L T
Sbjct: 3767 NGFLHIQSAHVT-------DTGRYLCMATNAAGTDRRRIDLQVH---VPPSIA--LGPTN 3814
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAG 1052
+ T L AG S+ W KN ++ N ++ L + S+ D
Sbjct: 3815 ITVTVNVQTTLACEAAGIPKPSIKWKKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 3874
Query: 1053 LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQ 1232
Y C V+NDAG T + ++ P P + D+ T + V++ ++C G I
Sbjct: 3875 TYECTVTNDAGEDQRTVDLTVQVP--PSIADEP-TDLLVTKHAPTIITCTASGVPFPSIH 3931
Query: 1233 WLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXX 1412
W K G + P + ++G +E AG Y C A N AGS + VT
Sbjct: 3932 WTKNGIRLLPREDGYRILSSG--AIEIFATQLNHAGRYTCIARNAAGS--AHRHVT---- 3983
Query: 1413 XXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQG 1592
V +P + V+ + G P P + W K + G
Sbjct: 3984 ---------LYVQEPPVIQPQPSELDVIVNNPILLPCEATGTPSPFITWQKEGINVITSG 4034
Query: 1593 GRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ G L+I + D+G Y CVA N G + L V
Sbjct: 4035 KSHAVLPNGG---LQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4077
Score = 95.1 bits (235), Expect = 2e-19
Identities = 80/268 (29%), Positives = 120/268 (44%), Gaps = 5/268 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFR--NNVATLVFNQVDSND 179
V + G+ L C+ G P ++W + + HF N + LV +V D
Sbjct: 4271 VSLNKGEQLRLSCKATGIPLPKLTWTFNNNII------PAHFDSVNGHSELVIERVSKED 4324
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQL-RDVQETVGLPVVFECAVSGSEPI 356
SG Y+C AENSVG V + F+ V+E PP F + E +G + C V G
Sbjct: 4325 SGTYVCTAENSVGFVKAIGFVYVKE---PPVFKGDYPSNWIEPLGGNAILNCEVKGDPAP 4381
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
++ W + G ++ I+ L N +L I+ T AG Y+C ATN G S L L
Sbjct: 4382 TIQWSRKGMDIEINHRIRQ--LVN-GSLAIYGTVNEDAGDYTCVATNDAGVVERSMSLTL 4438
Query: 537 TEGRNPPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
++PP I L PV+ V+ G C TG + W++ I + +++ L
Sbjct: 4439 ---QSPPI--ITLEPVETVINAGGKVILNCQATGEPYPTITWSRQGHSI--PWDDRVNVL 4491
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVG 794
N++ L I K DT +Y C A N +G
Sbjct: 4492 SNNS-LHIAAAQKEDTSEYECVARNLMG 4518
Score = 91.7 bits (226), Expect = 2e-18
Identities = 90/344 (26%), Positives = 140/344 (40%), Gaps = 2/344 (0%)
Frame = +3
Query: 705 YLENSAHLT--ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE 878
YL+ SA +T I KV D Y C AV+ G ++ E PP + + + V
Sbjct: 477 YLKESASVTWEIEKVTLSDEDTYECIAVSSAGTGRAQTFFDVSE---PPPIIQ-VPDNVT 532
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
G L V + ++ W +N+ + + N+ L +++ DAG Y
Sbjct: 533 VLPGERAILTCLVISAVDYNLTWQRNDRDARLADPARMRSLANSSL-ELRTVKFNDAGEY 591
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWL 1238
C VSN+ GS+ + + ++EP K V ++ + + G + + C G +I W
Sbjct: 592 QCVVSNEGGSSAASVFLTVQEPPKVTVMPKN---QSFTGGSEVSIRCSATGYPKPKITWT 648
Query: 1239 KAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXX 1418
I S R + + GT L K+ DAG Y C ASN AG+D S +
Sbjct: 649 INDMFIMGSHRYRMT-SEGT--LFIKNAIPKDAGIYGCLASNSAGTDKQTSTL------- 698
Query: 1419 XXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR 1598
++ V + + + + TT K G P+P VKW KG L
Sbjct: 699 -------RYIEAPKLVVVQSELLVALGDTT-VMECKSSGTPLPQVKWFKG---DLELRPS 747
Query: 1599 IFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
F+ L+I++T D+G Y CVA N G + L V
Sbjct: 748 PFLIIDPLLGLLKIQETQDLDAGDYTCVAVNDAGRAAGKITLDV 791
>ref|XP_548414.2| PREDICTED: similar to hemicentin 1 [Canis familiaris].
Length = 5069
Score = 170 bits (431), Expect = 4e-42
Identities = 156/584 (26%), Positives = 240/584 (41%), Gaps = 14/584 (2%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRN---NVA---TLVFNQVDSNDS 182
G ASL C G P ++W K T ++FR NV+ TLV Q + D+
Sbjct: 973 GVPASLPCMALGVPTPTITWTK--------ETNALNFRGPHYNVSKDGTLVITQRSAQDA 1024
Query: 183 GEYICRAENSVGEVSSSTFLTVQ-EQKLPPSFSRQLRD---VQETVGLPVVFECAVSGSE 350
G YIC A N+VG S +L+V E ++ + S+ + V G V +C GS
Sbjct: 1025 GAYICTATNTVGFSSQEMWLSVNTEPRIHVNGSQDAEEPLRVTAKAGDEVTLDCEAQGSP 1084
Query: 351 PISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
P V+W KD RP+ N L +L + Q +G Y CTA NP GSAS
Sbjct: 1085 PPLVTWTKDFRPMPSITNRHR--LLPSGSLRLAQAQVGDSGLYRCTANNPAGSASQH--- 1139
Query: 531 ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
+ + + PP + + GE D C G+ +++W+KD ++ GG
Sbjct: 1140 YIVQVQAPPQMQPGPRVLKVLAGEILDLNCMAEGSPEPQLSWSKDGVALQGGGP------ 1193
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF-TKKLSETVEETE 887
E S H + ++ D G Y C A N G D+ +L + E PP + + S +E
Sbjct: 1194 EGSIHFSAIRTH--DAGWYRCEASNSAGVDAWELELQVLE---PPYWEANETSGLLERVV 1248
Query: 888 GNSFRLEGRVAGSQPISVAWYK--NNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
G + L G+ V W+K ++ + E+ + + L V GD Y
Sbjct: 1249 GENASLPCPARGTPTPQVTWWKGPSSEPLRGRPGLEVLDEGSLFLASVSPTDSGD---YK 1305
Query: 1062 CKVSNDAGSALCTSSIVIKEPKKPPV-FDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWL 1238
C+ +N+AGS + +V+ P P + D H T V+ G+ L L C V G I WL
Sbjct: 1306 CQATNEAGSTSRRAKLVVYVP--PSIREDGHRTNVSGMAGQSLTLECDVNGFPAPEIVWL 1363
Query: 1239 KAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXX 1418
K G+ I + S + L + + D+G Y C+A N AG+
Sbjct: 1364 KDGQLI--PEASSHRLPDKPQALHLPRIQEGDSGLYSCRAENQAGT-------------A 1408
Query: 1419 XXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR 1598
+ + Q + + + G P P V+WTK L
Sbjct: 1409 QRDFHLLVLIPPSVLGSGAAQEVLGLAGAEVELKCRTSGVPTPQVEWTKDGQPILPGDPH 1468
Query: 1599 IFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ + + G L I + D G Y+CVAF+ G+ + L++
Sbjct: 1469 VQLQEDGQ--VLRITSSHLGDEGWYQCVAFSPAGQQAKDFQLRM 1510
Score = 161 bits (408), Expect = 2e-39
Identities = 123/465 (26%), Positives = 202/465 (43%), Gaps = 3/465 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ V + L C+ +G P ++W K + P + ++ D+G
Sbjct: 3953 VQALVAEEVLLPCEASGIPRPSITWQKEGLSI-PAGVNTQILPSGQLRII--HASPEDAG 4009
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C A+NS G T L VQ +PP+ L D+ T G + C+ SGS +++
Sbjct: 4010 NYFCLAQNSAGSAVGKTRLVVQ---VPPTIKTGLPDLSTTEGSHALLTCSASGSPEPTIT 4066
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W KDG P+ T + L + + AG Y+CTA N +G A R+ LT
Sbjct: 4067 WEKDGLPVSGAEGKFT--IQPSGELLVKNLESQDAGTYTCTAKNSVGHA--RRRVHLTIL 4122
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRS---GGNYQISYLEN 716
P F +P +G+ C G+ P ++ W ++R + G +S +
Sbjct: 4123 ALPVFTTLP-GDRSLRLGDRLWLRCAARGSPPPRIGWTVNDRPVMGLGLLGAEGVSEQDG 4181
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
+ L + V + D+G Y C+A N VG+ + + +KE P + + E G+S
Sbjct: 4182 GSTLQRVAVTREDSGTYVCWAENRVGRVQAVSFVQVKE---APVLQGEAFSYLVEPVGSS 4238
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
+L+ V G + W K+ + P + + L +++ M DAG Y C N
Sbjct: 4239 VQLDCVVHGVPAPDIRWIKDGL---PFRGSRLRHRLQNGSLSIRRTEMDDAGQYQCLAEN 4295
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
+ G+ +VI + PVF VTV E + L C G ++WL+AG+ +
Sbjct: 4296 EMGA---VEKVVILVLQSAPVFSVKPQDVTVRPREDVALQCQASGEPAPTVEWLRAGQPL 4352
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS 1391
+ S R + +G+ L + V DAG Y C A N+ GS T+++
Sbjct: 4353 RASQRLR-TLPDGS--LWLQRVEAGDAGTYECVAHNLLGSTTARA 4394
Score = 159 bits (401), Expect = 1e-38
Identities = 140/575 (24%), Positives = 225/575 (39%), Gaps = 7/575 (1%)
Frame = +3
Query: 27 SASLQCQLAGTPEIGVSWYKGDTKLRPTATYK-MHFRNNVATLVFNQVDSNDSGEYICRA 203
S +L+C +G P +SW+KG +P + +K + + L Q +D+G Y C A
Sbjct: 1894 SVTLECLASGVPPPDISWFKG---RQPVSAWKGVTVSADGRVLHIEQARFSDAGNYRCVA 1950
Query: 204 ENSVGEVSSSTFLTVQ---EQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFK 374
N G L V LPPS + + PV C +G+ ++ W K
Sbjct: 1951 SNVAGSTELQYGLRVNVPPRITLPPSLPGPV-----LLNAPVRLTCNATGAPSPTLMWLK 2005
Query: 375 DGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNP 554
DG P+ L + S +G YSC A + +G R ++ P
Sbjct: 2006 DGNPVSTAGPSGLQVFPGGRVLTLASARASDSGSYSCVAVSAVG---EDRRDVILSVHVP 2062
Query: 555 PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNR--EIRSGGNYQISYLENSAHL 728
P V V ES EC ++W KD E+R G I + A L
Sbjct: 2063 PSILGEELNVSVVANESVTLECQSQAVPLPVLSWRKDGHPLELRPG----IHLSADKALL 2118
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
+ + + GD G YTC A+N+ G+ LN+ +PP F + T+ T+G+ RL
Sbjct: 2119 EVSRAEVGDAGHYTCEALNQAGRSEKHYNLNV---WVPPVFPSREPRTLTVTKGHPARLS 2175
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
G ++W K+ + N LL + + G YTC+ SN AG+
Sbjct: 2176 CECRGIPFPKISWRKDGQPLPGEGNSLEQVSAVGRLLYLGQTQPAQEGTYTCECSNVAGN 2235
Query: 1089 ALCTSSIVIKEPKK-PPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
+ + + P + ++ H V +GE L C+ G P R+ W +AGR +
Sbjct: 2236 SSQDQLLEVHVPPQIAGPWEPHTQVSVVRDGE-ATLWCNASGKPPPRVTWERAGRPLGAE 2294
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
N L + A G Y C A N AG + ++
Sbjct: 2295 P--GLRLQNQGQSLRVERARAAHGGHYSCVAENAAGWAERRFALSVLEPPELIGDS---- 2348
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
+ ++ + T + + G P+P V+W +G+ ++ G ++ G
Sbjct: 2349 --------HQLTNVSAALHSPLTLLCEATGVPLPGVRWFRGE-EPISPGEDTYLLAGG-- 2397
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
L I + D GLY C+A N+ GE+ N +++V
Sbjct: 2398 WMLRITRAREQDRGLYSCLASNEAGEVRRNFSVEV 2432
Score = 158 bits (400), Expect = 2e-38
Identities = 163/581 (28%), Positives = 237/581 (40%), Gaps = 10/581 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLR---PTATYKMHFRNNVATLVFNQVDSNDS 182
+T ASL C+ G+P+ V W+K KL Y++ N L+ DS
Sbjct: 3771 LTAHTPASLPCEARGSPKPQVVWWKDGQKLDFHLQRGAYRLLPSN---ALLLTAPSPQDS 3827
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
++ C N VGE +T+ +PP+ + D T PVV C +G V
Sbjct: 3828 AQFECVVSNEVGEARRLYQVTIH---VPPTIADDQTDFTVTKMAPVVLTCHSTGIPAPLV 3884
Query: 363 SWFKDGRPL---KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
SW K G PL G + S L I Q G+Y+CTA N G A +
Sbjct: 3885 SWSKAGAPLGVRGSGYRVLPS-----GALEIGQALPIHTGRYTCTARNSAGVAHK--HVA 3937
Query: 534 LTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
LT +P +P + V A+V E C +G + W K+ I +G N QI
Sbjct: 3938 LTVQASPVVKPLP-SVVQALVAEEVLLPCEASGIPRPSITWQKEGLSIPAGVNTQIL--- 3993
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN 893
S L I+ D G Y C A N G +L ++ +PP+ L + + TEG+
Sbjct: 3994 PSGQLRIIHASPEDAGNYFCLAQNSAGSAVGKTRLVVQ---VPPTIKTGLPD-LSTTEGS 4049
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
L +GS ++ W K+ + + A + T + + LL VK DAG YTC
Sbjct: 4050 HALLTCSASGSPEPTITWEKDGLPV-SGAEGKFTIQPSGELL-VKNLESQDAGTYTCTAK 4107
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
N G A + I PVF ++ G+ L L C RGS P RI W R
Sbjct: 4108 NSVGHARRRVHLTI---LALPVFTTLPGDRSLRLGDRLWLRCAARGSPPPRIGWTVNDRP 4164
Query: 1254 IKPSDRC---SFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXX 1424
+ S +G + L+ VT+ D+G YVC A N G + S V
Sbjct: 4165 VMGLGLLGAEGVSEQDGGSTLQRVAVTREDSGTYVCWAENRVGRVQAVSFV--------- 4215
Query: 1425 XXXXXXXVDGKLF-FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRI 1601
+ G+ F ++ EP ++ V G P P+++W K +G R
Sbjct: 4216 QVKEAPVLQGEAFSYLVEPVG------SSVQLDCVVHGVPAPDIRWIKDGLP--FRGSR- 4266
Query: 1602 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNL 1724
+ + L IR T D+G Y+C+A N+ G +E V L
Sbjct: 4267 -LRHRLQNGSLSIRRTEMDDAGQYQCLAENEMGAVEKVVIL 4306
Score = 157 bits (398), Expect = 3e-38
Identities = 154/576 (26%), Positives = 232/576 (40%), Gaps = 8/576 (1%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENS 212
+LQC G P + W+K L L +VD D G Y C A +
Sbjct: 1813 TLQCVGTGAPTPSLRWWKDGVALAALG----------GKLQIEKVDLRDEGIYTCAATSL 1862
Query: 213 VGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLK 392
GE L V +PP+ + V EC SG P +SWFK +P+
Sbjct: 1863 AGESKRDVTLKVL---VPPNIEPGPLNKAVLENASVTLECLASGVPPPDISWFKGRQPVS 1919
Query: 393 DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIP 572
+ S V L+I Q S AG Y C A+N GS L + PP +P
Sbjct: 1920 AWKGVTVSADGRV--LHIEQARFSDAGNYRCVASNVAGSTELQYGLRVNV---PPRITLP 1974
Query: 573 LA-PVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDK 749
+ P ++ C+ TG + W KD + + G + LT+
Sbjct: 1975 PSLPGPVLLNAPVRLTCNATGAPSPTLMWLKDGNPVSTAGPSGLQVFPGGRVLTLASARA 2034
Query: 750 GDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKLSETVEETEGNSFRLEGRVAGS 926
D+G Y+C AV+ VG+D L++ +PPS ++L+ +V E + + +
Sbjct: 2035 SDSGSYSCVAVSAVGEDRRDVILSVH---VPPSILGEELNVSVVANESVTLECQSQAV-- 2089
Query: 927 QPISV-AWYKNN--VEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
P+ V +W K+ +E+ P I + LL+V +A +GDAG YTC+ N AG +
Sbjct: 2090 -PLPVLSWRKDGHPLELRP----GIHLSADKALLEVSRAEVGDAGHYTCEALNQAGRSEK 2144
Query: 1098 TSSIVIKEPKKPPVF-DQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRC 1274
++ + PPVF + +TV++G +LSC RG +I W K G+ + P +
Sbjct: 2145 HYNLNV---WVPPVFPSREPRTLTVTKGHPARLSCECRGIPFPKISWRKDGQPL-PGEGN 2200
Query: 1275 SFSFANGTAVLEFKDVTK-ADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVD 1451
S + L + T+ A G Y C+ SNVAG+ + + V
Sbjct: 2201 SLEQVSAVGRLLYLGQTQPAQEGTYTCECSNVAGNSSQDQLL-------------EVHVP 2247
Query: 1452 GKLFFVSEPQS-IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
++ EP + + VV AT G P P V W + R L + + +G
Sbjct: 2248 PQIAGPWEPHTQVSVVRDGEATLWCNASGKPPPRVTWERA-GRPLGAEPGLRLQNQGQ-- 2304
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
L + G Y CVA N G E L V E
Sbjct: 2305 SLRVERARAAHGGHYSCVAENAAGWAERRFALSVLE 2340
Score = 155 bits (392), Expect = 1e-37
Identities = 148/609 (24%), Positives = 235/609 (38%), Gaps = 32/609 (5%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT+ + SL C+ P ++W K A+ + L D+G
Sbjct: 2543 VTVTINNPISLICEALAFPSPTITWMKDGAPFE--ASNNIQLLPGTHGLQILNAQKEDAG 2600
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQ-------LRDVQETVGLPVVFECAVSG 344
+Y C N +GE + + V +PPS S+ +++V+ V + EC
Sbjct: 2601 QYTCVVTNELGEAMKNYHVEVL---IPPSISKDDPLGEASVKEVRTKVNSTLTLECECWA 2657
Query: 345 SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
P +++W+KDG+P+ P+ + L L I T S +G+Y C ATN G
Sbjct: 2658 MPPPTITWYKDGQPVT--PSERLHLLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDF 2715
Query: 525 RLILTE-------GRNPPFFDIPLAPVDA----------VVGESADFECHVTGTQPIKVA 653
+++ G F+IP +A V A C P ++
Sbjct: 2716 NVLIQVPPMFQKLGEASAAFEIPSREQEARSGVMEYREIVENNPAYLYCDTNAVPPPELT 2775
Query: 654 WAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKER 833
W ++++ + + +S L+ L I V D G+Y+C A NEVG+D QL +
Sbjct: 2776 WYREDQPLLATDG--VSVLQGGRVLQIPLVRAEDAGRYSCKASNEVGEDWLHYQLLV--- 2830
Query: 834 LIPPSFTKKLSETVEETEGN---SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKN 1004
L PP E VEE N + L+ G+ +++W +N + P+ ++
Sbjct: 2831 LTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPMPTISWLQNGLPFAPSPRLQVL--E 2888
Query: 1005 NALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEF 1184
+ +LQV A + DA Y C N AGS+ ++ ++ P +L VT
Sbjct: 2889 DGQVLQVSTAEVADAASYMCVAENPAGSSEKLFTLRVQGP--------NLEQVTAIVNSS 2940
Query: 1185 LQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASN 1364
+ LSC V + W + + + GT L+ +D+G Y C+A N
Sbjct: 2941 VSLSCDVHAHPSPEVTWYRDSQALSLGK--EVFLLPGTHTLQLARAQPSDSGMYACEALN 2998
Query: 1365 VAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDP 1541
AG D +++ S P + +V A + P
Sbjct: 2999 AAGRDQKLVQLSVLVPPTFRQPP------------SSPHDVILVRAGDKAVLNCETDSLP 3046
Query: 1542 IPNVKWTKGKWRQLNQGGRIFIHQK----GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIE 1709
P V W K G + + Q+ D +LEIRDT D GLY C N GE
Sbjct: 3047 EPTVTWHK-------DGQPLVLAQRTQALQDGQRLEIRDTQVLDKGLYSCKVRNTAGEAM 3099
Query: 1710 SNVNLQVNE 1736
L V E
Sbjct: 3100 RTFVLTVQE 3108
Score = 153 bits (386), Expect = 7e-37
Identities = 149/591 (25%), Positives = 233/591 (39%), Gaps = 8/591 (1%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTK--LRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VG++ASL C GTP V+W+KG + LR ++ + +L V DSG+Y
Sbjct: 1248 VGENASLPCPARGTPTPQVTWWKGPSSEPLRGRPGLEV---LDEGSLFLASVSPTDSGDY 1304
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSR--QLRDVQETVGLPVVFECAVSGSEPISVS 365
C+A N G S L V +PPS +V G + EC V+G +
Sbjct: 1305 KCQATNEAGSTSRRAKLVVY---VPPSIREDGHRTNVSGMAGQSLTLECDVNGFPAPEIV 1361
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W KDG+ + + + + D L++ + +G YSC A N G+A L++
Sbjct: 1362 WLKDGQLIPEASSHRLP--DKPQALHLPRIQEGDSGLYSCRAENQAGTAQRDFHLLVL-- 1417
Query: 546 RNPP--FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
PP V + G + +C +G +V W KD + I G + + E+
Sbjct: 1418 -IPPSVLGSGAAQEVLGLAGAEVELKCRTSGVPTPQVEWTKDGQPILPGDPH-VQLQEDG 1475
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF--TKKLSETVEETEGN 893
L I GD G Y C A + G+ + QL ++ +PP+ + + SE V EG+
Sbjct: 1476 QVLRITSSHLGDEGWYQCVAFSPAGQQAKDFQLRMQ---VPPTIWGSNETSE-VAVMEGH 1531
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
R G + W+K+ + +A E + LQ+ +A DAG YTC+ S
Sbjct: 1532 PVRFLCEARGVPAPDITWFKDGASLPLSA--EAVYTRGGRQLQLGRARGLDAGTYTCQAS 1589
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
N G T+ + + P V G L L C RG P + W G
Sbjct: 1590 NPVGVTEKTTRLEVYVPPTIEGAGGGPRVVKAVAGRPLALECVARGQPPPTLSWHHEGLP 1649
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
+ S+ G VL + + +A G Y C AS+ AG + V
Sbjct: 1650 VAESNETWLE--AGGRVLTLEGLGEASGGLYNCVASSPAGEAVLQYSV------------ 1695
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
V +L + + + G P+P ++W R + + +
Sbjct: 1696 -EVQVPPQLLVAEGVGQVTALVGQPLELSCQASGSPVPTLQWLH-NGRPAEELAGVQVAS 1753
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGD 1766
+G A L+I GL C A N+ G + V L V+E + + GD
Sbjct: 1754 RG--AMLQISRVEPGHEGLLACQATNEAGTAGAEVELSVHELPEVAIVGGD 1802
Score = 153 bits (386), Expect = 7e-37
Identities = 149/584 (25%), Positives = 224/584 (38%), Gaps = 18/584 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V A+L C +G P V+W + L A + +N +L + + G
Sbjct: 2260 VSVVRDGEATLWCNASGKPPPRVTWERAGRPLG--AEPGLRLQNQGQSLRVERARAAHGG 2317
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C AEN+ G L+V E S QL +V + P+ C +G V
Sbjct: 2318 HYSCVAENAAGWAERRFALSVLEPPELIGDSHQLTNVSAALHSPLTLLCEATGVPLPGVR 2377
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WF+ P+ G + T L L I + G YSC A+N G R E
Sbjct: 2378 WFRGEEPISPGED--TYLLAGGWMLRITRAREQDRGLYSCLASNEAGEV---RRNFSVEV 2432
Query: 546 RNPPFFDIPL--APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
PP + V G++A C+ TG KV W KD R + G + IS +
Sbjct: 2433 LVPPRIENESLEEAVKVPEGQTAHLTCNATGHPQPKVMWFKDGRPLTGGDAHHIS--PDG 2490
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEE----TE 887
A L +L+ + +G Y+C A N VG+ + QL++ L+ P+ ++ +E T
Sbjct: 2491 ALLQVLQANLSSSGHYSCIAANAVGEKTKHFQLSV---LVVPTILGVTEDSADEEVTVTI 2547
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
N L ++ W K+ + N ++ + LQ+ A DAG YTC
Sbjct: 2548 NNPISLICEALAFPSPTITWMKDGAPFEASNNIQLLPGTHG--LQILNAQKEDAGQYTCV 2605
Query: 1068 VSNDAGSALCTSSIVIKEP----KKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQW 1235
V+N+ G A+ + + P K P+ + + V L L C P I W
Sbjct: 2606 VTNELGEAMKNYHVEVLIPPSISKDDPLGEASVKEVRTKVNSTLTLECECWAMPPPTITW 2665
Query: 1236 LKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXX 1415
K G+ + PS+R +L+ + +D+G Y+C A+NVAG D V
Sbjct: 2666 YKDGQPVTPSER--LHLLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNV---LIQ 2720
Query: 1416 XXXXXXXXXXVDGKLFFVSEPQSIR--------VVEKTTATFIAKVGGDPIPNVKWTKGK 1571
S Q R +VE A P P + W +
Sbjct: 2721 VPPMFQKLGEASAAFEIPSREQEARSGVMEYREIVENNPAYLYCDTNAVPPPELTWYRED 2780
Query: 1572 WRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
L G + + Q G L+I D+G Y C A N+ GE
Sbjct: 2781 QPLLATDG-VSVLQGG--RVLQIPLVRAEDAGRYSCKASNEVGE 2821
Score = 148 bits (373), Expect = 2e-35
Identities = 163/619 (26%), Positives = 249/619 (40%), Gaps = 10/619 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ V+ G++A L CQ+ ++W + D ++ +T ++ +++ L +++ +D G
Sbjct: 513 ITVSPGETAILSCQVLSAVPYNLTWIR-DWRVLAASTGRVTQLADLS-LEVSRITPSDGG 570
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C A N+ G +S +L VQE P S + + G+ V C+ SG +S
Sbjct: 571 RYQCMASNANGVTRASIWLLVQE---APQVSIHTQSQHFSQGMEVRVSCSASGYPTPHIS 627
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W +G L++ I +D TL I AG YSC A N +G+ + L T+
Sbjct: 628 WNHEGHALQEDSRIH---VDAQGTLIIQGVAPEDAGNYSCQAVNEVGTDEETVTLYYTD- 683
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP A V A VGE A C V+G +V W + GG I E S+
Sbjct: 684 --PPTASAVNAVVLAAVGEEAVLLCEVSGVPLPRVIWYR-------GGLEMILAPEGSSS 734
Query: 726 --LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I + D G YTC AVNE+G+ S +L + P T +L V G S
Sbjct: 735 GTLRIPAARERDAGIYTCRAVNEMGEASAEIRLEVGH---APQLT-ELPRDVTVELGRSA 790
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L R G P V W + + + T + ++ +L + D Y C+ N
Sbjct: 791 LLACRALGRPPPIVTWRRGDGQPLGPRRGSRTGQPDSGVLFFESVVPEDQASYVCEAQNV 850
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI-RIQWLKAGREI 1256
G + +V+ PP + V V EG+ + L C + P+ +WLKAG +
Sbjct: 851 FGKVWAEAWLVV-TGHAPPQIASSASTVRVLEGQPVSLPCIILAGRPLPERRWLKAGLPL 909
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
P + S A+G+ L + DAG Y C +N AGS ++
Sbjct: 910 PPGSQHSIR-ADGS--LHLDRALQEDAGRYSCVVTNTAGSQHRDVELVVQVPPRI----- 961
Query: 1437 XXXVDGKLFFVSEPQSIRVV--EKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
+P + V E A+ G P P + WTK + LN G +
Sbjct: 962 ------------QPTATHHVTNEGVPASLPCMALGVPTPTITWTK-ETNALNFRGPHYNV 1008
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK-----QEKIEGDLRA 1775
K + L I + D+G Y C A N G + L VN + + E LR
Sbjct: 1009 SK--DGTLVITQRSAQDAGAYICTATNTVGFSSQEMWLSVNTEPRIHVNGSQDAEEPLRV 1066
Query: 1776 MLKKTPVLKKGAGEEEEID 1832
K AG+E +D
Sbjct: 1067 TAK--------AGDEVTLD 1077
Score = 147 bits (371), Expect = 4e-35
Identities = 145/585 (24%), Positives = 227/585 (38%), Gaps = 10/585 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKG--DTKLRPTATYKMHFRNNVATLVFNQVDSND 179
V V +S +L+CQ P +SW K +LRP +H + A L ++ + D
Sbjct: 2072 VSVVANESVTLECQSQAVPLPVLSWRKDGHPLELRP----GIHLSADKALLEVSRAEVGD 2127
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSF-SRQLRDVQETVGLPVVFECAVSGSEPI 356
+G Y C A N G L V +PP F SR+ R + T G P C G
Sbjct: 2128 AGHYTCEALNQAGRSEKHYNLNVW---VPPVFPSREPRTLTVTKGHPARLSCECRGIPFP 2184
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
+SW KDG+PL N L + QT + G Y+C +N G++S L
Sbjct: 2185 KISWRKDGQPLPGEGNSLEQVSAVGRLLYLGQTQPAQEGTYTCECSNVAGNSSQDQ---L 2241
Query: 537 TEGRNPPFFDIPLAP---VDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISY 707
E PP P P V V A C+ +G P +V W + R + G +
Sbjct: 2242 LEVHVPPQIAGPWEPHTQVSVVRDGEATLWCNASGKPPPRVTWERAGRPL--GAEPGLRL 2299
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE--TVEE 881
L + + G Y+C A N G L++ E PP + V
Sbjct: 2300 QNQGQSLRVERARAAHGGHYSCVAENAAGWAERRFALSVLE---PPELIGDSHQLTNVSA 2356
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
+ L G V W++ I P + + +L++ +A D GLY+
Sbjct: 2357 ALHSPLTLLCEATGVPLPGVRWFRGEEPISPGEDTYLL--AGGWMLRITRAREQDRGLYS 2414
Query: 1062 CKVSNDAGSALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWL 1238
C SN+AG S+ + P P + ++ L V V EG+ L+C+ G ++ W
Sbjct: 2415 CLASNEAGEVRRNFSVEVLVP--PRIENESLEEAVKVPEGQTAHLTCNATGHPQPKVMWF 2472
Query: 1239 KAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXX 1418
K GR + D + + A+L+ + +G Y C A+N G T +++
Sbjct: 2473 KDGRPLTGGD--AHHISPDGALLQVLQANLSSSGHYSCIAANAVGEKTKHFQLSVLVVPT 2530
Query: 1419 XXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQLNQGG 1595
S + + V + I + P P + W K G + +
Sbjct: 2531 ILGVTED----------SADEEVTVTINNPISLICEALAFPSPTITWMKDGAPFEASNNI 2580
Query: 1596 RIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
++ G L+I + K D+G Y CV N+ GE N +++V
Sbjct: 2581 QLLPGTHG----LQILNAQKEDAGQYTCVVTNELGEAMKNYHVEV 2621
Score = 145 bits (365), Expect = 2e-34
Identities = 145/574 (25%), Positives = 214/574 (37%), Gaps = 13/574 (2%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G+ ++ C + G+ I VSW K L + + H N+ TL +QV DSG + C
Sbjct: 3322 GELVTMACPVRGSAPIRVSWLKDGLPL--PLSQRTHLHNSGRTLRISQVQLADSGIFTCV 3379
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFS--RQLRDVQETVGLPVVFECAVSGSEPISVSWFK 374
A + G + L V +PP DV G VV C GS VSW K
Sbjct: 3380 AASPAGVTDRNFTLQVH---VPPVLEPVEVQNDVAVVRGSSVVLPCEARGSPLPLVSWMK 3436
Query: 375 DGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNP 554
DG PL L+ +L + AG YSC A + G A +L + + P
Sbjct: 3437 DGEPLLP------QSLEQGPSLLLETAGAGDAGTYSCVAVSEAGEARRHFQLTVMD---P 3487
Query: 555 PFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREI---RSGGNYQISYLENS 719
P+ + P + ++ G + C G P + W KD + + R G
Sbjct: 3488 PYIEDSGQPAELLLTPGTPLELHCEARGNPPPNITWHKDGQGLGRPRDGNRV-------- 3539
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L + V GD G YTC A + G+ + + ++ P + +V
Sbjct: 3540 --LRVESVQVGDAGLYTCLAQSPAGEAEKSFWVRVQGP--PHVIGPRGPRSVVGLAPGQL 3595
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
LE V + W+++ V + A+ + F LQ++ S D G Y+C N
Sbjct: 3596 VLECSVEAEPAPQIEWHRDGVLLQADAHTQ--FPEQGRFLQLQALSTADGGNYSCTAQNA 3653
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS TS E P V S + L C V G+ P + W K G +
Sbjct: 3654 AGS---TSVAFHVEIHMVPTIQPGPPTVNASINQTALLPCQVDGAPPPLVSWRKDGATLD 3710
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
P+ G+ L + V DAG Y+C ASN AGSD +
Sbjct: 3711 PNSPRLQVLPEGS--LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLQVFEPPA------- 3761
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH-QK 1616
P ++ + T A+ + G P P V W K G ++ H Q+
Sbjct: 3762 --------ITPSPSNLTLTAHTPASLPCEARGSPKPQVVWWK-------DGQKLDFHLQR 3806
Query: 1617 G-----DEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
G L + + DS + CV N+ GE
Sbjct: 3807 GAYRLLPSNALLLTAPSPQDSAQFECVVSNEVGE 3840
Score = 144 bits (363), Expect = 3e-34
Identities = 156/630 (24%), Positives = 230/630 (36%), Gaps = 55/630 (8%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G L C+ G P V+W K L + F + + LV + + DSG Y
Sbjct: 3175 VLEGQEVRLDCEADGQPPPDVTWLKDGGPLDQGVGPHLRFYLDGSALVLKGLKAQDSGAY 3234
Query: 192 ICRAENSVGEVSSSTFLTVQEQKL------------------------------------ 263
C A N+ GE + ++V ++L
Sbjct: 3235 TCVAHNAAGEDARLHTVSVLGERLRAEARRELCYPGAAAAWPVVGPPMEGDTGARMRKTW 3294
Query: 264 ---------PPSFSRQLRDVQETVGLP---VVFECAVSGSEPISVSWFKDGRPLKDGPNI 407
PP+ + V P V C V GS PI VSW KDG PL P
Sbjct: 3295 FKPRPCPHLPPTIEQWAESSGTLVSRPGELVTMACPVRGSAPIRVSWLKDGLPL---PLS 3351
Query: 408 QTSFLDNVA-TLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPV 584
Q + L N TL I Q + +G ++C A +P G + L + PP +
Sbjct: 3352 QRTHLHNSGRTLRISQVQLADSGIFTCVAASPAGVTDRNFTL---QVHVPPVLEPVEVQN 3408
Query: 585 DAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDT 758
D V G S C G+ V+W KD + LE L + GD
Sbjct: 3409 DVAVVRGSSVVLPCEARGSPLPLVSWMKDGEPLLP------QSLEQGPSLLLETAGAGDA 3462
Query: 759 GQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE--ETEGNSFRLEGRVAGSQP 932
G Y+C AV+E G+ QL + + P + + + E T G L G+ P
Sbjct: 3463 GTYSCVAVSEAGEARRHFQLTVMD----PPYIEDSGQPAELLLTPGTPLELHCEARGNPP 3518
Query: 933 ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIV 1112
++ W+K+ + ++ +L+V+ +GDAGLYTC + AG A S
Sbjct: 3519 PNITWHKDGQGLGRP-------RDGNRVLRVESVQVGDAGLYTCLAQSPAGEA--EKSFW 3569
Query: 1113 IKEPKKPPVFDQH--LTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSF 1286
++ P V + V ++ G+ L L C V +I+W + G ++ F
Sbjct: 3570 VRVQGPPHVIGPRGPRSVVGLAPGQ-LVLECSVEAEPAPQIEWHRDGVLLQAD--AHTQF 3626
Query: 1287 ANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFF 1466
L+ + ++ AD G+Y C A N AGS + V
Sbjct: 3627 PEQGRFLQLQALSTADGGNYSCTAQNAAGSTSVAFHVEIHMVPTIQPG------------ 3674
Query: 1467 VSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRD 1646
P ++ TA +V G P P V W K R+ Q E L I+
Sbjct: 3675 ---PPTVNASINQTALLPCQVDGAPPPLVSWRKDGATLDPNSPRL---QVLPEGSLRIQP 3728
Query: 1647 TTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
D+G Y C+A N G +LQV E
Sbjct: 3729 VLAQDAGHYLCLASNSAGSDRQGRDLQVFE 3758
Score = 140 bits (354), Expect = 3e-33
Identities = 155/676 (22%), Positives = 247/676 (36%), Gaps = 92/676 (13%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
++ + A L C P ++WY+ D L AT + L V + D+G
Sbjct: 2753 EIVENNPAYLYCDTNAVPPPELTWYREDQPL--LATDGVSVLQGGRVLQIPLVRAEDAGR 2810
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQL-RDVQETVGLPVVFECAVSGSEPISVS 365
Y C+A N VGE L V + + +L +V V +C G+ ++S
Sbjct: 2811 YSCKASNEVGEDWLHYQLLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPMPTIS 2870
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W ++G P P +Q L++ L + + + A Y C A NP GS S + +G
Sbjct: 2871 WLQNGLPFAPSPRLQV--LEDGQVLQVSTAEVADAASYMCVAENPAGS-SEKLFTLRVQG 2927
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
N L V A+V S C V +V W +D++ + G ++ L +
Sbjct: 2928 PN-------LEQVTAIVNSSVSLSCDVHAHPSPEVTWYRDSQALSLGK--EVFLLPGTHT 2978
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLS---ETVEETEGNS 896
L + + D+G Y C A+N G+D QL++ L+PP+F + S + + G+
Sbjct: 2979 LQLARAQPSDSGMYACEALNAAGRDQKLVQLSV---LVPPTFRQPPSSPHDVILVRAGDK 3035
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
L +V W+K+ + + + L+++ + D GLY+CKV N
Sbjct: 3036 AVLNCETDSLPEPTVTWHKDGQPLVLAQRTQAL--QDGQRLEIRDTQVLDKGLYSCKVRN 3093
Query: 1077 DAGSALCTSSIVIKEPK-----------------KPPVFDQH------------------ 1151
AG A+ T + ++E KP +
Sbjct: 3094 TAGEAMRTFVLTVQESSVVHGVVSRGGRLQLSRLKPAQAGTYTCVAENTQAEARKDFVVA 3153
Query: 1152 -LTPVTVS---------------EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFS 1283
L P TV+ EG+ ++L C G P + WLK G +
Sbjct: 3154 VLAPATVAPRIRSLGATQEHSVLEGQEVRLDCEADGQPPPDVTWLKDGGPLDQGVGPHLR 3213
Query: 1284 FANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDG--- 1454
F + L K + D+G Y C A N AG D V+ G
Sbjct: 3214 FYLDGSALVLKGLKAQDSGAYTCVAHNAAGEDARLHTVSVLGERLRAEARRELCYPGAAA 3273
Query: 1455 ------------------KLFFVSE-----PQSIRVVEKTTATFIAKVG----------G 1535
K +F P +I +++ T +++ G G
Sbjct: 3274 AWPVVGPPMEGDTGARMRKTWFKPRPCPHLPPTIEQWAESSGTLVSRPGELVTMACPVRG 3333
Query: 1536 DPIPNVKWTK-GKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIES 1712
V W K G L+Q R +H G L I DSG++ CVA + G +
Sbjct: 3334 SAPIRVSWLKDGLPLPLSQ--RTHLHNSG--RTLRISQVQLADSGIFTCVAASPAGVTDR 3389
Query: 1713 NVNLQVNERKKQEKIE 1760
N LQV+ E +E
Sbjct: 3390 NFTLQVHVPPVLEPVE 3405
Score = 139 bits (349), Expect = 1e-32
Identities = 150/584 (25%), Positives = 226/584 (38%), Gaps = 7/584 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V ++ +A L CQ+ G P VSW K L P + +L V + D+G
Sbjct: 3678 VNASINQTALLPCQVDGAPPPLVSWRKDGATLDPNSPRLQVLPE--GSLRIQPVLAQDAG 3735
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y+C A NS G L V E PP+ + ++ T P C GS V
Sbjct: 3736 HYLCLASNSAGSDRQGRDLQVFE---PPAITPSPSNLTLTAHTPASLPCEARGSPKPQVV 3792
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+KDG+ L L L + + Q+ C +N +G A RL
Sbjct: 3793 WWKDGQKLDFHLQRGAYRLLPSNALLLTAPSPQDSAQFECVVSNEVGEA---RRLYQVTI 3849
Query: 546 RNPPFFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDNREIR-SGGNYQISYLEN 716
PP I D V + A CH TG V+W+K + G Y++
Sbjct: 3850 HVPP--TIADDQTDFTVTKMAPVVLTCHSTGIPAPLVSWSKAGAPLGVRGSGYRVL---P 3904
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
S L I + TG+YTC A N G A ++ + K L V+
Sbjct: 3905 SGALEIGQALPIHTGRYTCTARNSAG----VAHKHVALTVQASPVVKPLPSVVQALVAEE 3960
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
L +G S+ W K + I N +I L++ AS DAG Y C N
Sbjct: 3961 VLLPCEASGIPRPSITWQKEGLSIPAGVNTQILPSGQ---LRIIHASPEDAGNYFCLAQN 4017
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
AGSA+ + +V+ + PP L ++ +EG L+C GS I W K G +
Sbjct: 4018 SAGSAVGKTRLVV---QVPPTIKTGLPDLSTTEGSHALLTCSASGSPEPTITWEKDGLPV 4074
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
++ F+ +L K++ DAG Y C A N G + +T
Sbjct: 4075 SGAEG-KFTIQPSGELL-VKNLESQDAGTYTCTAKNSVGHARRRVHLTILALP------- 4125
Query: 1437 XXXVDGKLFFVSEP--QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQG--GRIF 1604
F + P +S+R+ ++ A+ G P P + WT + G G
Sbjct: 4126 --------VFTTLPGDRSLRLGDRLWLRCAAR--GSPPPRIGWTVNDRPVMGLGLLGAEG 4175
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ ++ + L+ T+ DSG Y C A N+ G +++ +QV E
Sbjct: 4176 VSEQDGGSTLQRVAVTREDSGTYVCWAENRVGRVQAVSFVQVKE 4219
Score = 138 bits (347), Expect = 2e-32
Identities = 145/586 (24%), Positives = 218/586 (37%), Gaps = 13/586 (2%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVF-NQVDSNDSGE 188
VT G A L C+ G P +SW K D + P + + V L++ Q G
Sbjct: 2166 VTKGHPARLSCECRGIPFPKISWRK-DGQPLPGEGNSLEQVSAVGRLLYLGQTQPAQEGT 2224
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFS---------RQLRDVQETVGLPVVFECAVS 341
Y C N G S L V +PP + +RD + T+ C S
Sbjct: 2225 YTCECSNVAGNSSQDQLLEVH---VPPQIAGPWEPHTQVSVVRDGEATLW------CNAS 2275
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
G P V+W + GRPL P ++ + +L + + + G YSC A N G A
Sbjct: 2276 GKPPPRVTWERAGRPLGAEPGLRLQ--NQGQSLRVERARAAHGGHYSCVAENAAGWAERR 2333
Query: 522 ARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
L + E L V A + C TG V W + I G + +
Sbjct: 2334 FALSVLEPPELIGDSHQLTNVSAALHSPLTLLCEATGVPLPGVRWFRGEEPISPGEDTYL 2393
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF-TKKLSETVE 878
L L I + + D G Y+C A NE G+ + + L+PP + L E V+
Sbjct: 2394 --LAGGWMLRITRAREQDRGLYSCLASNEAGEVRRNFSVEV---LVPPRIENESLEEAVK 2448
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
EG + L G V W+K+ + T + LLQV +A++ +G Y
Sbjct: 2449 VPEGQTAHLTCNATGHPQPKVMWFKDGRPL--TGGDAHHISPDGALLQVLQANLSSSGHY 2506
Query: 1059 TCKVSNDAGSAL--CTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQ 1232
+C +N G S+++ D VTV+ + L C I
Sbjct: 2507 SCIAANAVGEKTKHFQLSVLVVPTILGVTEDSADEEVTVTINNPISLICEALAFPSPTIT 2566
Query: 1233 WLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXX 1412
W+K G + S+ + GT L+ + K DAG Y C +N G V
Sbjct: 2567 WMKDGAPFEASN--NIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAMKNYHVEVLIP 2624
Query: 1413 XXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQG 1592
K +R +T T + P P + W K + +
Sbjct: 2625 PSISKDDPLGEASVK--------EVRTKVNSTLTLECECWAMPPPTITWYK-DGQPVTPS 2675
Query: 1593 GRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
R +H G+ L+I+ T +DSG Y CVA N GE + + N+ +
Sbjct: 2676 ER--LHLLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLI 2719
Score = 137 bits (345), Expect = 4e-32
Identities = 143/595 (24%), Positives = 224/595 (37%), Gaps = 19/595 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G C+ G P ++W+K L P + ++ R L + D+G
Sbjct: 1525 VAVMEGHPVRFLCEARGVPAPDITWFKDGASL-PLSAEAVYTRGG-RQLQLGRARGLDAG 1582
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C+A N VG +T L V R V+ G P+ EC G P ++S
Sbjct: 1583 TYTCQASNPVGVTEKTTRLEVYVPPTIEGAGGGPRVVKAVAGRPLALECVARGQPPPTLS 1642
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSA--------SSS 521
W +G P+ + V TL + G Y+C A++P G A
Sbjct: 1643 WHHEGLPVAESNETWLEAGGRVLTLE--GLGEASGGLYNCVASSPAGEAVLQYSVEVQVP 1700
Query: 522 ARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
+L++ EG + V A+VG+ + C +G+ + W + R Q+
Sbjct: 1701 PQLLVAEG---------VGQVTALVGQPLELSCQASGSPVPTLQWLHNGRPAEELAGVQV 1751
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
+ A L I +V+ G G C A NE G +L++ E L + + TV
Sbjct: 1752 A--SRGAMLQISRVEPGHEGLLACQATNEAGTAGAEVELSVHE-LPEVAIVGGDNITVPF 1808
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
+ + + G G+ S+ W+K+ V + LQ++K + D G+YT
Sbjct: 1809 LQPVTLQCVG--TGAPTPSLRWWKDGVALAALGG----------KLQIEKVDLRDEGIYT 1856
Query: 1062 CKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLK 1241
C ++ AG + V + PP + V E + L C G P I W K
Sbjct: 1857 CAATSLAGE---SKRDVTLKVLVPPNIEPGPLNKAVLENASVTLECLASGVPPPDISWFK 1913
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
+ + + S A+G VL + +DAG+Y C ASNVAGS + +
Sbjct: 1914 GRQPVSAWKGVTVS-ADG-RVLHIEQARFSDAGNYRCVASNVAGSTELQYGLRVNVPPR- 1970
Query: 1422 XXXXXXXXVDGKLFFVSEPQSI--RVVEKTTATFIAKVGGDPIPNVKWTKG--------- 1568
++ P S+ V+ G P P + W K
Sbjct: 1971 ---------------ITLPPSLPGPVLLNAPVRLTCNATGAPSPTLMWLKDGNPVSTAGP 2015
Query: 1569 KWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
Q+ GGR+ L + +DSG Y CVA + GE +V L V+
Sbjct: 2016 SGLQVFPGGRV----------LTLASARASDSGSYSCVAVSAVGEDRRDVILSVH 2060
Score = 137 bits (344), Expect = 5e-32
Identities = 146/569 (25%), Positives = 210/569 (36%), Gaps = 4/569 (0%)
Frame = +3
Query: 36 LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSV 215
L C G P VSW K L + + L Q +G Y C A NS
Sbjct: 3872 LTCHSTGIPAPLVSWSKAGAPLGVRGSGYRVLPSGA--LEIGQALPIHTGRYTCTARNSA 3929
Query: 216 GEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKD 395
G LTVQ P VQ V V+ C SG S++W K+G +
Sbjct: 3930 GVAHKHVALTVQAS---PVVKPLPSVVQALVAEEVLLPCEASGIPRPSITWQKEGLSIPA 3986
Query: 396 GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPL 575
G N Q + L I AG Y C A N GSA RL++ + PP L
Sbjct: 3987 GVNTQ---ILPSGQLRIIHASPEDAGNYFCLAQNSAGSAVGKTRLVV---QVPPTIKTGL 4040
Query: 576 APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGD 755
+ G A C +G+ + W KD + SG + + ++ S L + ++ D
Sbjct: 4041 PDLSTTEGSHALLTCSASGSPEPTITWEKDGLPV-SGAEGKFT-IQPSGELLVKNLESQD 4098
Query: 756 TGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPI 935
G YTC A N VG L I L P FT + G+ L GS P
Sbjct: 4099 AGTYTCTAKNSVGHARRRVHLTI---LALPVFTTLPGDRSLRL-GDRLWLRCAARGSPPP 4154
Query: 936 SVAWYKNNVEIHPTANCE---ITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS 1106
+ W N+ + ++ ++ LQ + D+G Y C N G S
Sbjct: 4155 RIGWTVNDRPVMGLGLLGAEGVSEQDGGSTLQRVAVTREDSGTYVCWAENRVGRVQAVSF 4214
Query: 1107 IVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSF 1286
+ +KE P + + + + G +QL C V G I+W+K G + S R
Sbjct: 4215 VQVKEA--PVLQGEAFSYLVEPVGSSVQLDCVVHGVPAPDIRWIKDGLPFRGS-RLRHRL 4271
Query: 1287 ANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFF 1466
NG+ L + DAG Y C A N G+ KV + F
Sbjct: 4272 QNGS--LSIRRTEMDDAGQYQCLAENEMGA---VEKVVILV------------LQSAPVF 4314
Query: 1467 VSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQLNQGGRIFIHQKGDEAKLEIR 1643
+PQ + V + + G+P P V+W + G+ + +Q R + L ++
Sbjct: 4315 SVKPQDVTVRPREDVALQCQASGEPAPTVEWLRAGQPLRASQRLRTL-----PDGSLWLQ 4369
Query: 1644 DTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
D+G Y CVA N G + L V
Sbjct: 4370 RVEAGDAGTYECVAHNLLGSTTARAILSV 4398
Score = 128 bits (322), Expect = 2e-29
Identities = 144/611 (23%), Positives = 230/611 (37%), Gaps = 13/611 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G S L C+ G+P VSW K L P + +L+ + D+G
Sbjct: 3410 VAVVRGSSVVLPCEARGSPLPLVSWMKDGEPLLPQSL------EQGPSLLLETAGAGDAG 3463
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C A + GE LTV + PP S Q ++ T G P+ C G+ P +
Sbjct: 3464 TYSCVAVSEAGEARRHFQLTVMD---PPYIEDSGQPAELLLTPGTPLELHCEARGNPPPN 3520
Query: 360 VSWFKDGRPL---KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
++W KDG+ L +DG + L + AG Y+C A +P G A S
Sbjct: 3521 ITWHKDGQGLGRPRDGNRV----------LRVESVQVGDAGLYTCLAQSPAGEAEKS--- 3567
Query: 531 ILTEGRNPPFFDIPLAPVDAVVGESAD---FECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
+ PP P P +VVG + EC V ++ W +D +++ + Q
Sbjct: 3568 FWVRVQGPPHVIGPRGP-RSVVGLAPGQLVLECSVEAEPAPQIEWHRDGVLLQADAHTQ- 3625
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
+ E L + + D G Y+C A N G S + +++ ++P + TV
Sbjct: 3626 -FPEQGRFLQLQALSTADGGNYSCTAQNAAG--STSVAFHVEIHMVPT--IQPGPPTVNA 3680
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
+ + L +V G+ P V+W K+ + P + +L +Q A DAG Y
Sbjct: 3681 SINQTALLPCQVDGAPPPLVSWRKDGATLDPNSPRLQVLPEGSLRIQPVLAQ--DAGHYL 3738
Query: 1062 CKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLK 1241
C SN AGS + + E PP + +T++ L C RGS ++ W K
Sbjct: 3739 CLASNSAGSDRQGRDLQVFE---PPAITPSPSNLTLTAHTPASLPCEARGSPKPQVVWWK 3795
Query: 1242 AGREIK-PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXX 1418
G+++ R ++ A+L + D+ + C SN G +VT
Sbjct: 3796 DGQKLDFHLQRGAYRLLPSNALL-LTAPSPQDSAQFECVVSNEVGEARRLYQVTIHVPPT 3854
Query: 1419 XXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR 1598
+ V + G P P V W+K G
Sbjct: 3855 ---------------IADDQTDFTVTKMAPVVLTCHSTGIPAPLVSWSKA-------GAP 3892
Query: 1599 IFIHQKG----DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGD 1766
+ + G LEI +G Y C A N G +V L V + +
Sbjct: 3893 LGVRGSGYRVLPSGALEIGQALPIHTGRYTCTARNSAGVAHKHVALTVQASPVVKPLPSV 3952
Query: 1767 LRAMLKKTPVL 1799
++A++ + +L
Sbjct: 3953 VQALVAEEVLL 3963
Score = 126 bits (317), Expect = 7e-29
Identities = 144/587 (24%), Positives = 221/587 (37%), Gaps = 10/587 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTK--LRPTATYKMHFRNNVATLVFNQVDSND 179
V VG+ A L C+++G P V WY+G + L P ++ TL D
Sbjct: 694 VLAAVGEEAVLLCEVSGVPLPRVIWYRGGLEMILAPEG-------SSSGTLRIPAARERD 746
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
+G Y CRA N +GE S+ L V P + RDV +G + C G P
Sbjct: 747 AGIYTCRAVNEMGEASAEIRLEVGH---APQLTELPRDVTVELGRSALLACRALGRPPPI 803
Query: 360 VSWFK-DGRPLKDGPNIQTSFLDNVATL--NIFQTDRSFAGQYSCTATNPIGSASSSARL 530
V+W + DG+PL +T D+ ++ D++ Y C A N G + A L
Sbjct: 804 VTWRRGDGQPLGPRRGSRTGQPDSGVLFFESVVPEDQA---SYVCEAQNVFGKVWAEAWL 860
Query: 531 ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPI-KVAWAKDNREIRSGGNYQISY 707
++T G PP + V + G+ C + +P+ + W K + G + I
Sbjct: 861 VVT-GHAPPQIASSASTVRVLEGQPVSLPCIILAGRPLPERRWLKAGLPLPPGSQHSIR- 918
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
+ S HL + + D G+Y+C N G +L ++ +PP + V E
Sbjct: 919 ADGSLHLD--RALQEDAGRYSCVVTNTAGSQHRDVELVVQ---VPPRIQPTATHHV-TNE 972
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
G L G ++ W K ++ K+ L++ + A DAG Y C
Sbjct: 973 GVPASLPCMALGVPTPTITWTKETNALNFRGPHYNVSKDGTLVITQRSAQ--DAGAYICT 1030
Query: 1068 VSNDAGSALCTSSIVIK-EPKKPPVFDQHLTP---VTVSEGEFLQLSCHVRGSEPIRIQW 1235
+N G + + + EP+ Q VT G+ + L C +GS P + W
Sbjct: 1031 ATNTVGFSSQEMWLSVNTEPRIHVNGSQDAEEPLRVTAKAGDEVTLDCEAQGSPPPLVTW 1090
Query: 1236 LKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXX 1415
K R + +G+ L D+G Y C A+N AGS + V
Sbjct: 1091 TKDFRPMPSITNRHRLLPSGS--LRLAQAQVGDSGLYRCTANNPAGSASQHYIV------ 1142
Query: 1416 XXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGG 1595
V P+ ++V+ G P P + W+K QGG
Sbjct: 1143 ---------QVQAPPQMQPGPRVLKVLAGEILDLNCMAEGSPEPQLSWSKD--GVALQGG 1191
Query: 1596 RIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
G E + D+G YRC A N G + LQV E
Sbjct: 1192 -------GPEGSIHFSAIRTHDAGWYRCEASNSAGVDAWELELQVLE 1231
Score = 119 bits (299), Expect = 8e-27
Identities = 123/526 (23%), Positives = 196/526 (37%), Gaps = 3/526 (0%)
Frame = +3
Query: 162 QVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVS 341
+ + G Y C A + G + + V + PP ++ + G + C V
Sbjct: 472 RASKTEEGVYECTAVSRAGTGRAKAQIVVTD---PPPQLIPAPNITVSPGETAILSCQVL 528
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
+ P +++W +D R L T D +L + + S G+Y C A+N G +S
Sbjct: 529 SAVPYNLTWIRDWRVLAASTGRVTQLAD--LSLEVSRITPSDGGRYQCMASNANGVTRAS 586
Query: 522 ARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
L++ E P I G C +G ++W + ++ +
Sbjct: 587 IWLLVQEA---PQVSIHTQSQHFSQGMEVRVSCSASGYPTPHISWNHEGHALQEDSRIHV 643
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
+ L I V D G Y+C AVNEVG D T L + P ++ V
Sbjct: 644 ---DAQGTLIIQGVAPEDAGNYSCQAVNEVGTDEETVTLYYTD----PPTASAVNAVVLA 696
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVE--IHPTANCEITFKNNALLLQVKKASMGDAGL 1055
G L V+G V WY+ +E + P + T L++ A DAG+
Sbjct: 697 AVGEEAVLLCEVSGVPLPRVIWYRGGLEMILAPEGSSSGT-------LRIPAARERDAGI 749
Query: 1056 YTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQW 1235
YTC+ N+ G A S+ + E P + VTV G L+C G P + W
Sbjct: 750 YTCRAVNEMGEA---SAEIRLEVGHAPQLTELPRDVTVELGRSALLACRALGRPPPIVTW 806
Query: 1236 LKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXX 1415
+ + R S + + VL F+ V D YVC+A NV G +++ +
Sbjct: 807 RRGDGQPLGPRRGSRTGQPDSGVLFFESVVPEDQASYVCEAQNVFGKVWAEAWLVVTGHA 866
Query: 1416 XXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKV-GGDPIPNVKWTKGKWRQLNQG 1592
S ++RV+E + + G P+P +W K L G
Sbjct: 867 PPQ-------------IASSASTVRVLEGQPVSLPCIILAGRPLPERRWLKA-GLPLPPG 912
Query: 1593 GRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ H + L + + D+G Y CV N G +V L V
Sbjct: 913 SQ---HSIRADGSLHLDRALQEDAGRYSCVVTNTAGSQHRDVELVV 955
Score = 101 bits (252), Expect = 2e-21
Identities = 98/379 (25%), Positives = 156/379 (41%), Gaps = 8/379 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ T G A L C +G+PE ++W K + A K + + LV N ++S D+G
Sbjct: 4043 LSTTEGSHALLTCSASGSPEPTITWEKDGLPVSG-AEGKFTIQPSGELLVKN-LESQDAG 4100
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C A+NSVG LT+ P F+ D +G + CA GS P +
Sbjct: 4101 TYTCTAKNSVGHARRRVHLTILAL---PVFTTLPGDRSLRLGDRLWLRCAARGSPPPRIG 4157
Query: 366 WFKDGRPLK-------DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
W + RP+ +G + Q D +TL R +G Y C A N +G + +
Sbjct: 4158 WTVNDRPVMGLGLLGAEGVSEQ----DGGSTLQRVAVTREDSGTYVCWAENRVGRVQAVS 4213
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
+ + E P + + VG S +C V G + W KD R ++
Sbjct: 4214 FVQVKEA--PVLQGEAFSYLVEPVGSSVQLDCVVHGVPAPDIRWIKDGLPFRGS---RLR 4268
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE-TVEE 881
+ + L+I + + D GQY C A NE+G L ++ P F+ K + TV
Sbjct: 4269 HRLQNGSLSIRRTEMDDAGQYQCLAENEMGAVEKVVILVLQSA---PVFSVKPQDVTVRP 4325
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
E L+ + +G +V W + + + T + +L LQ + GDAG Y
Sbjct: 4326 RE--DVALQCQASGEPAPTVEWLRAGQPLRASQRLR-TLPDGSLWLQ--RVEAGDAGTYE 4380
Query: 1062 CKVSNDAGSALCTSSIVIK 1118
C N GS + + ++
Sbjct: 4381 CVAHNLLGSTTARAILSVR 4399
Score = 94.4 bits (233), Expect = 4e-19
Identities = 89/401 (22%), Positives = 162/401 (40%), Gaps = 7/401 (1%)
Frame = +3
Query: 618 CHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGK 797
C V T P ++ ++ + ++Q+S ++ I + K + G Y C AV+ G
Sbjct: 435 CSVHSTLPFRLQLRRNGARLGEERHFQVS---GNSSWEIPRASKTEEGVYECTAVSRAGT 491
Query: 798 DSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPT 977
AQ+ + + PP + TV + G + L +V + P ++ W ++ +
Sbjct: 492 GRAKAQIVVTDP--PPQLIPAPNITV--SPGETAILSCQVLSAVPYNLTWIRD-WRVLAA 546
Query: 978 ANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT 1157
+ +T + L L+V + + D G Y C SN G + ++++E P H
Sbjct: 547 STGRVTQLAD-LSLEVSRITPSDGGRYQCMASNANGVTRASIWLLVQEA---PQVSIHTQ 602
Query: 1158 PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADA 1337
S+G +++SC G I W G ++ R A GT +++ V DA
Sbjct: 603 SQHFSQGMEVRVSCSASGYPTPHISWNHEGHALQEDSRIHVD-AQGTLIIQ--GVAPEDA 659
Query: 1338 GDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTT--- 1508
G+Y C+A N G+D + VT + ++P + V
Sbjct: 660 GNYSCQAVNEVGTD--EETVT--------------------LYYTDPPTASAVNAVVLAA 697
Query: 1509 ----ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYR 1676
A + +V G P+P V W +G I + L I + D+G+Y
Sbjct: 698 VGEEAVLLCEVSGVPLPRVIWYRGGLEM------ILAPEGSSSGTLRIPAARERDAGIYT 751
Query: 1677 CVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVL 1799
C A N+ GE + + L+V + ++ D+ L ++ +L
Sbjct: 752 CRAVNEMGEASAEIRLEVGHAPQLTELPRDVTVELGRSALL 792
>ref|XP_544815.2| PREDICTED: similar to Roundabout homolog 2 precursor [Canis
familiaris].
Length = 1378
Score = 155 bits (393), Expect = 1e-37
Identities = 144/517 (27%), Positives = 218/517 (42%), Gaps = 20/517 (3%)
Frame = +3
Query: 246 VQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPL---KDGPNIQTS 416
++++ PP DV + G P C G ++ W+KDG + KD P
Sbjct: 24 LRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRM 83
Query: 417 FL--DNVATLNIFQTDRS--FAGQYSCTATNPIGSA-SSSARLILTEGRNPPFFDIPLAP 581
L ++ L I RS G Y C A N +G A S +A L + R+ D P
Sbjct: 84 LLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRD----DFRQNP 139
Query: 582 VDAVV--GESADFECHVTGTQP-IKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKG 752
D VV GE A EC P + W KD I +IS L I K
Sbjct: 140 TDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRI-DDKEERISI--RGGKLMISNTRKS 196
Query: 753 DTGQYTCYAVNEVG-KDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQ 929
D G YTC N VG +DS A+L + ER P + +++ V E E FR + V G
Sbjct: 197 DAGMYTCVGTNMVGERDSDPAELTVFER--PTFLRRPINQVVLEEEAVEFRCQ--VQGDP 252
Query: 930 PISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSI 1109
+V W K++ ++ P +I + L++KKA D G Y C N G ++S+
Sbjct: 253 QPTVRWKKDDADL-PRGRYDI---KDDYTLRIKKAMSTDEGTYLCIAENRVGKVEASASL 308
Query: 1110 VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE--------IKPS 1265
+ + PP F V++G + C +G+ + W K G + +P+
Sbjct: 309 TV---RAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPN 365
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
RCS S T L ++ ++DAG Y+C+A VAGS +K+++
Sbjct: 366 SRCSVS---PTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPP---- 418
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
+ P + + TA K GDP+P + W K + L + R I ++G
Sbjct: 419 -----IILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFLGRDSRATIQEQG-- 471
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
L+I++ +D+G Y CVA + GE + L V E
Sbjct: 472 -TLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTE 507
Score = 137 bits (344), Expect = 5e-32
Identities = 125/482 (25%), Positives = 197/482 (40%), Gaps = 18/482 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKG----DTKLRPTATYKMHFRNN---VATLVFNQ 164
V V+ G+ +L C+ G P + WYK +T +++M + +V +
Sbjct: 40 VIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 99
Query: 165 VDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSG 344
D G Y+C A N +GE S +++ L F + DV G P + EC
Sbjct: 100 RSKPDEGSYVCVARNYLGEAVSRN-ASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPR 158
Query: 345 SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
P ++K + D + S L I T +S AG Y+C TN +G S
Sbjct: 159 GHPEPTIYWKKDKVRIDDKEERISI--RGGKLMISNTRKSDAGMYTCVGTNMVGERDSDP 216
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
LT P F P+ V + E+ +F C V G V W KD+ ++ G Y I
Sbjct: 217 -AELTVFERPTFLRRPINQV-VLEEEAVEFRCQVQGDPQPTVRWKKDDADL-PRGRYDI- 272
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
++ L I K D G Y C A N VGK +A L ++ PP F + + +
Sbjct: 273 --KDDYTLRIKKAMSTDEGTYLCIAENRVGKVEASASLTVR---APPQFVVRPRDQI-VA 326
Query: 885 EGNSFRLEGRVAGSQPISVAWYKN--------NVEIHPTANCEITFKNNALLLQVKKASM 1040
+G + G+ +V W K N P + C ++ + + ++++
Sbjct: 327 QGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRS-- 384
Query: 1041 GDAGLYTCKVSNDAGSALCTSSIVIKE---PKKPPVFDQHLTPVTVSEGEFLQLSCHVRG 1211
DAG Y C+ AGS L + + + + + PP+ Q T++ L C G
Sbjct: 385 -DAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATG 443
Query: 1212 SEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS 1391
I WLK G D + GT L+ K++ +D G Y C A++ +G +TS S
Sbjct: 444 DPLPVISWLKEGFTFLGRDSRATIQEQGT--LQIKNLRISDTGTYTCVATSSSG-ETSWS 500
Query: 1392 KV 1397
V
Sbjct: 501 AV 502
Score = 104 bits (259), Expect = 4e-22
Identities = 85/278 (30%), Positives = 121/278 (43%), Gaps = 9/278 (3%)
Frame = +3
Query: 24 DSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRA 203
++ +CQ+ G P+ V W K D L P Y + + TL + S D G Y+C A
Sbjct: 240 EAVEFRCQVQGDPQPTVRWKKDDADL-PRGRYDI---KDDYTLRIKKAMSTDEGTYLCIA 295
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGR 383
EN VG+V +S LTV + PP F + RD G V F C G+ +V W K+G
Sbjct: 296 ENRVGKVEASASLTV---RAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGS 352
Query: 384 P------LKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE- 542
PN + S + L I RS AG Y C A GS + A+L +T+
Sbjct: 353 QNLLFPNQPQQPNSRCS-VSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDV 411
Query: 543 --GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
R PP A V +A +C TG ++W K+ G + ++
Sbjct: 412 LTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFL--GRDSRATIQE 469
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKE 830
L I + DTG YTC A + G+ S +A L++ E
Sbjct: 470 QGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTE 507
>ref|XP_544814.2| PREDICTED: similar to roundabout 1 isoform a [Canis familiaris].
Length = 1702
Score = 154 bits (390), Expect = 2e-37
Identities = 137/473 (28%), Positives = 195/473 (41%), Gaps = 16/473 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKG----DTKLRPTATYKMHFRNN---VATLVFNQVD 170
V+ G+ A+L C+ G P + WYKG +T +++M + +V +
Sbjct: 130 VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 189
Query: 171 SNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
D G Y+C A N +GE S +++ L F + DV VG P V EC
Sbjct: 190 RPDEGVYVCVARNYLGEAVSHN-ASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGH 248
Query: 351 P-ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSAR 527
P ++SW KDG PL D T L I T +S AG+Y C TN +G S
Sbjct: 249 PEPTISWKKDGSPLDDKDERITI---RGGKLMITYTRKSDAGKYVCVGTNMVGERESEV- 304
Query: 528 LILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISY 707
LT P F P + + V +SA+F+C G V W KD+ E+ Y+I
Sbjct: 305 AELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRYEI-- 360
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
+ L I KV GD G YTC A N VGK +A L ++E PP F K + V
Sbjct: 361 -RDDHTLKIRKVMAGDMGSYTCVAENMVGKAEASATLTVQE---PPHFVVKPRDQVVAL- 415
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVE-----IHPTANCEITFKNNALLLQVKKASMGDAG 1052
G + + G+ ++ W + + P + + L + D G
Sbjct: 416 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSTSRFSVSQTGDLTITNVQRSDVG 475
Query: 1053 LYTCKVSNDAGSALCTSSIVIKE---PKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
Y C+ N AGS + + + + + + PPV Q TV+ L LSC GS
Sbjct: 476 YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLVLSCVATGSPMP 535
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
I W K G + D G VL+ + D G Y C AS +G T
Sbjct: 536 TILWRKDGVLVSTQDSRIKQLETG--VLQIRYAKLGDTGRYTCIASTPSGEAT 586
Score = 132 bits (333), Expect = 9e-31
Identities = 139/546 (25%), Positives = 218/546 (39%), Gaps = 25/546 (4%)
Frame = +3
Query: 174 NDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEP 353
ND+G I ++N + T ++++ PP D+ + G P C G
Sbjct: 89 NDNGTPIPTSDNDDNSLGY-TGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPT 147
Query: 354 ISVSWFKDGRPL---KDGPNIQTSFLDNVATLNIF----QTDRSFAGQYSCTATNPIGSA 512
++ W+K G + KD P L + + + + R G Y C A N +G A
Sbjct: 148 PTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEA 207
Query: 513 SSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIK-VAWAKDNREIRS-- 683
S + F P + V VGE A EC P ++W KD +
Sbjct: 208 VSHNASLEVAILRDDFRQNP-SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKD 266
Query: 684 ------GGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVG-KDSCTAQLNIKERLIP 842
GG I+Y K D G+Y C N VG ++S A+L + ER
Sbjct: 267 ERITIRGGKLMITYTR-----------KSDAGKYVCVGTNMVGERESEVAELTVLER--- 312
Query: 843 PSFTKKLSE-TVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLL 1019
PSF K+ S V + F+ E R G +V W K++ E+ P + EI + L
Sbjct: 313 PSFVKRPSNLAVTVDDSAEFKCEAR--GDPVPTVRWRKDDGEL-PKSRYEIRDDHT---L 366
Query: 1020 QVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSC 1199
+++K GD G YTC N G A ++++ ++E PP F V+ G + C
Sbjct: 367 KIRKVMAGDMGSYTCVAENMVGKAEASATLTVQE---PPHFVVKPRDQVVALGRTVTFQC 423
Query: 1200 HVRGSEPIRIQWLKAGRE-----IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASN 1364
G+ I W + G + +P S + T L +V ++D G Y+C+ N
Sbjct: 424 EATGNPQPAIFWRREGSQNLLFSYQPPQSTSRFSVSQTGDLTITNVQRSDVGYYICQTLN 483
Query: 1365 VAGSDTSKS--KVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGD 1538
VAGS +K+ +VT V+ Q++ V + +A G
Sbjct: 484 VAGSIITKAYLEVTDVIADRPPPVIRQGPVN---------QTVAVDGTLVLSCVAT--GS 532
Query: 1539 PIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNV 1718
P+P + W K Q RI ++ + L+IR D+G Y C+A GE +
Sbjct: 533 PMPTILWRKDGVLVSTQDSRI---KQLETGVLQIRYAKLGDTGRYTCIASTPSGEATWSA 589
Query: 1719 NLQVNE 1736
++V E
Sbjct: 590 YIEVQE 595
Score = 113 bits (282), Expect = 8e-25
Identities = 93/287 (32%), Positives = 131/287 (45%), Gaps = 10/287 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VTV DSA +C+ G P V W K D +L P + Y++ + TL +V + D G Y
Sbjct: 324 VTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDDH---TLKIRKVMAGDMGSY 379
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C AEN VG+ +S LTVQE PP F + RD +G V F+C +G+ ++ W
Sbjct: 380 TCVAENMVGKAEASATLTVQE---PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR 436
Query: 372 KDGRP---LKDGPNIQTS--FLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
++G P TS + L I RS G Y C N GS + A L +
Sbjct: 437 REGSQNLLFSYQPPQSTSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV 496
Query: 537 TE---GRNPPFFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
T+ R PP I PV+ V C TG+ + W KD + S + +I
Sbjct: 497 TDVIADRPPPV--IRQGPVNQTVAVDGTLVLSCVATGSPMPTILWRKDG-VLVSTQDSRI 553
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP 842
LE L I GDTG+YTC A G+ + +A + ++E +P
Sbjct: 554 KQLETGV-LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVP 599
>ref|XP_544893.2| PREDICTED: similar to Down syndrome cell adhesion molecule precursor
(CHD2) [Canis familiaris].
Length = 1993
Score = 154 bits (389), Expect = 3e-37
Identities = 151/579 (26%), Positives = 234/579 (40%), Gaps = 15/579 (2%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
K G L C+ G PE W K + L + F+ V L+ +DSG
Sbjct: 234 KAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSG----RFQKTVTGLLIENTRPSDSGS 289
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y+C N G L V++ P + R V+ +VG V C+V+GSE +SW
Sbjct: 290 YVCEVSNRYGTAKVIGRLYVKQ---PLKATISPRKVKSSVGSQVSLSCSVTGSEDQELSW 346
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+++G L G N++ + + N L + +S G Y C SA +++L +G
Sbjct: 347 YRNGEILNPGKNVRITGI-NHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGT 405
Query: 549 N---PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
F + ++P + V C+V GT + W D+ I GG+++IS + S
Sbjct: 406 PKIISAFSEKVVSPAEPV-----SLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITS 460
Query: 720 -----AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
++L I D G Y C A N G A++N++ P S + + +
Sbjct: 461 EGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG---PASI--RPMKNITAI 515
Query: 885 EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTC 1064
G + RV G S+ WYKN+ + P + ++ F+NN L D G YTC
Sbjct: 516 AGRDTYIHCRVIGYPYYSIKWYKNS-NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC 574
Query: 1065 KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSC-HVRGSEPIRIQWLK 1241
V L TS V K PP F Q S G+ + + C V G PI I W K
Sbjct: 575 NVL--VQPQLSTSQSVHVTVKVPP-FIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQK 631
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
GR I S + + T+ L +++ G+Y C A N A + +S++
Sbjct: 632 DGRPIPASLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPK- 690
Query: 1422 XXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW--TKG----KWRQL 1583
FV +P+ + G P+P + W +KG +++ +
Sbjct: 691 --------------FVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPI 736
Query: 1584 NQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG 1700
GRI + G L I+ + DSG Y C N G
Sbjct: 737 ALNGRIQVLSNG---SLLIKHVVEEDSGYYLCKVSNDVG 772
Score = 134 bits (338), Expect = 2e-31
Identities = 144/608 (23%), Positives = 244/608 (40%), Gaps = 23/608 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK +VG SL C + G+ + +SWY+ L P ++ N+ L+ + + +D G
Sbjct: 322 VKSSVGSQVSLSCSVTGSEDQELSWYRNGEILNPGKNVRITGINH-ENLIMDHMVKSDGG 380
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C ++S+ ++ V + P + + PV C V G+ +++
Sbjct: 381 AYQCFVRKD--KLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTIT 438
Query: 366 WFKDGRPLKDGPNIQTSFL-----DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
W D P+ G + + S + + V+ LNI + G Y CTA N G AR+
Sbjct: 439 WTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARI 498
Query: 531 ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
+ R P P+ + A+ G C V G + W K N + + Q+++
Sbjct: 499 NV---RGPASIR-PMKNITAIAGRDTYIHCRVIGYPYYSIKWYK-NSNLLPFNHRQVAF- 552
Query: 711 ENSAHLTILKVDKG-DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
EN+ L + V K D G+YTC + + QL+ + + T K+ ++ E
Sbjct: 553 ENNGTLKLSDVQKEVDEGEYTCNVLVQ-------PQLSTSQSV---HVTVKVPPFIQPFE 602
Query: 888 GNSFRLEGRV-------AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGD 1046
F + RV +G PI++ W K+ I + I + L++ S+
Sbjct: 603 FPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPASLGVTIDNIDFTSSLRISNLSLMH 662
Query: 1047 AGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIR 1226
G YTC N+A + S ++++ P K V + + G+ + L+C G
Sbjct: 663 NGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIY---GKAVILNCSAEGYPVPT 719
Query: 1227 IQW-LKAGREIKPSDRCSFS-----FANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSK 1388
I W G + + + +NG+ ++ K V + D+G Y+CK SN G+D SK
Sbjct: 720 IVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLI--KHVVEEDSGYYLCKVSNDVGADVSK 777
Query: 1389 SKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG 1568
S V S P + + G+ V+W K
Sbjct: 778 S--------------MYLTVKIPAMITSYPNTTLATQGQKKEMSCAAHGEKPIIVRWEKE 823
Query: 1569 KWRQLNQGGRIFIHQK--GDE--AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ R + K G+E + L+I T + DSG + C A N +GE + L V E
Sbjct: 824 DRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQE 883
Query: 1737 RKKQEKIE 1760
+IE
Sbjct: 884 PPDPPEIE 891
Score = 108 bits (271), Expect = 1e-23
Identities = 143/581 (24%), Positives = 224/581 (38%), Gaps = 35/581 (6%)
Frame = +3
Query: 42 CQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS-----GEYICRAE 206
C AG P + + WY + H N +F S+ S Y C AE
Sbjct: 45 CPAAGVPPVSLRWYLATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAE 104
Query: 207 NSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEP---ISVSWFKD 377
N G++ S + P ++ ++ D + G VF+C + S VSW KD
Sbjct: 105 NPSGKIRSQDVHIKAVLREP--YTVRVEDQKTMRGNVAVFKCIIPSSVEAYVTVVSWEKD 162
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSC-TATNPIGSA--SSSARLILTEGR 548
L G + + ++ D + Y C T G + S+SARL +++
Sbjct: 163 TVSLISGSRFLITSTGALYIKDVQNEDGLY--NYRCITRHRYTGESRHSNSARLFVSDPA 220
Query: 549 N--PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
N P D A+ G+ + C G W KDN + G +Q +
Sbjct: 221 NSAPSILD-GFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQ----KTVT 275
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I D+G Y C N G +L +K+ L +K+ +V G+
Sbjct: 276 GLLIENTRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSV----GSQVS 331
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L V GS+ ++WY+N ++P N IT N+ L+ + D G Y C V D
Sbjct: 332 LSCSVTGSEDQELSWYRNGEILNPGKNVRITGINHENLI-MDHMVKSDGGAYQCFVRKDK 390
Query: 1083 GSALCTSSIVIKE--PKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQW------- 1235
SA +V+++ PK F + + VS E + L C+V+G+ I W
Sbjct: 391 LSAQDYVQVVLEDGTPKIISAFSEKV----VSPAEPVSLMCNVKGTPLPTITWTLDDDPI 446
Query: 1236 LKAGREIKPSDRCSFSFANGTAVLEFKDVTKA---DAGDYVCKASNVAGSDTSKSKVTXX 1406
LK G S R S + V+ + +++ + D G Y C A+N AG ++++
Sbjct: 447 LKGG-----SHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARIN-- 499
Query: 1407 XXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTA-----TFI-AKVGGDPIPNVKWTKG 1568
V P SIR ++ TA T+I +V G P ++KW K
Sbjct: 500 --------------------VRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYK- 538
Query: 1569 KWRQLNQGGRIFIHQK---GDEAKLEIRDTTK-TDSGLYRC 1679
N F H++ + L++ D K D G Y C
Sbjct: 539 -----NSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC 574
Score = 79.3 bits (194), Expect = 1e-14
Identities = 72/297 (24%), Positives = 123/297 (41%), Gaps = 13/297 (4%)
Frame = +3
Query: 9 KVTVGDSASLQCQL-AGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ ++G + C + +G I ++W K + + + + ++L + + +G
Sbjct: 605 RFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPASLGVTIDNIDFTSSLRISNLSLMHNG 664
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C A N V + L V ++PP F Q RD G V+ C+ G ++
Sbjct: 665 NYTCIARNEAAAVEHQSQLIV---RVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIV 721
Query: 366 W-FKDG------RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
W F G +P+ IQ ++ ++ + D +G Y C +N +G A S
Sbjct: 722 WKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEED---SGYYLCKVSNDVG-ADVSK 777
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSG-GNYQI 701
+ LT P + A G+ + C G +PI V W K++R I Y +
Sbjct: 778 SMYLTVKIPAMITSYPNTTL-ATQGQKKEMSCAAHGEKPIIVRWEKEDRIINPEMARYLV 836
Query: 702 SYLENSAH----LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKK 860
S E L IL + D+G ++C+A+N G+D QL ++E PP K
Sbjct: 837 STKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIK 893
>ref|XP_855194.1| PREDICTED: similar to Basement membrane-specific heparan sulfate
proteoglycan core protein precursor (HSPG) (Perlecan)
(PLC) [Canis familiaris].
Length = 1740
Score = 150 bits (379), Expect = 4e-36
Identities = 142/601 (23%), Positives = 238/601 (39%), Gaps = 15/601 (2%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDS--- 173
PV+V VG S +L+C AG P W ++ NNV ++ VDS
Sbjct: 548 PVRVKVGKSVTLECVSAGEPRSSARW------------TRIGAPNNVEQRMYGVVDSHTV 595
Query: 174 --------NDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSR-QLRDVQETV--GLPV 320
+D+G Y+C A+N++G + V + P + Q+ + + TV G
Sbjct: 596 LQISSAKPSDAGTYVCLAQNALGTAQKRVEVIVDTGTVAPGAPQVQVEEAELTVEAGHTA 655
Query: 321 VFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNP 500
C+ +GS ++ W K PL +Q TL I + + +GQY C AT+P
Sbjct: 656 TLRCSATGSPMPTIHWSKLRSPLPWQHQLQGD------TLIIPRVAQQDSGQYICNATSP 709
Query: 501 IGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIR 680
G A ++ L + +PP+ GE+ +C GT P+ W+ R
Sbjct: 710 AGHAEATIALHV---ESPPYATTVPEHTSVRAGETVQLQCLAHGTPPLTFQWS------R 760
Query: 681 SGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKK 860
GG+ + L V D+G+Y C N+VG AQ+ ++ T +
Sbjct: 761 VGGSLPARATARNELLRFESVAPEDSGRYRCQVTNKVGSAEAFAQVFVQGSTPTVQVTPQ 820
Query: 861 LSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASM 1040
L ++ G S V + + W K ++ P + + +L+++
Sbjct: 821 LE---TKSIGASVEFHCAVPSDRGTQLRWIKEGGQLPPGHSVQDG------VLRIQNLDQ 871
Query: 1041 GDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPV-TVSEGEFLQLSCHVRGSE 1217
G Y C+ G A ++ +V++ P V T V TV G ++ C G
Sbjct: 872 SCQGTYICQAHGPWGQAQASAQLVVQ--ALPSVLINIRTSVQTVVVGHAVEFECLALGDP 929
Query: 1218 PIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
++ W K G ++P ++ V ADAG Y C A+N AG T++S V
Sbjct: 930 KPQVTWSKVGGRLRP------GIVQSGGIVRIAHVELADAGQYRCTATNSAG--TTQSHV 981
Query: 1398 TXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWR 1577
L +S P +RV + A F G P P++ W+K
Sbjct: 982 LLLVQ--------------ALPQISTPPEVRVPAGSAAAFPCMASGYPTPDITWSK---- 1023
Query: 1578 QLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKI 1757
G + + + L + D+G Y C A N+ G+ ++ +LQV + ++ +I
Sbjct: 1024 ---LDGNLPPDSRLENNMLLLPSVRPQDAGTYVCTATNRQGKGQAFAHLQVPDAYRKFEI 1080
Query: 1758 E 1760
+
Sbjct: 1081 K 1081
Score = 134 bits (337), Expect = 3e-31
Identities = 147/621 (23%), Positives = 249/621 (40%), Gaps = 34/621 (5%)
Frame = +3
Query: 162 QVDSNDSGEYICRAENSVGEVSSSTFLTVQEQ--KLPPSFSRQLR--DVQETV--GLPVV 323
QV DSGEY+C N G +S +T++ PS S +R TV G +
Sbjct: 16 QVTPADSGEYVCHVSNGGGSQETSLIVTIEGSGPSHVPSVSPPIRIESSSPTVVEGQTLD 75
Query: 324 FECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPI 503
C V+G +++W+K G L T + + L + + +G+Y C A N I
Sbjct: 76 LNCVVAGQPQATITWYKRGGSLP------TQHQAHGSRLRLHHMSVADSGEYVCRANNNI 129
Query: 504 GSASSSARLILTEGRNPPFFDIPLAPV-------DAVVGESADFECHVTGTQPIKVAWAK 662
+ +S + ++ G P P+ G++ D C V G +V W K
Sbjct: 130 DAQETSIMVSVSPGAGSPSVPGGAVPIRIESSSSHVAEGQTVDLNCVVPGQAHAQVTWHK 189
Query: 663 DNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIK---ER 833
GG+ + + + L + +V D+G+Y C + + +NI+
Sbjct: 190 ------RGGSLPTHHQAHGSRLRLYQVSPADSGEYVCRVGSSSDPLEASVLVNIEASGSS 243
Query: 834 LIP---PSFTKKL---SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEIT 995
IP P ++ + + + EG + L V G V W++ +
Sbjct: 244 AIPAPAPGGSQPIRIETSSSHVAEGQTLDLNCVVPGQAHAQVTWHRRG------GSLPAR 297
Query: 996 FKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKP----------PVFD 1145
+ + LL++ + S D+G Y+C+V++ +G+ L S +V EP P P++
Sbjct: 298 HQVHGPLLRLNQVSPADSGEYSCQVTSSSGT-LEASVLVTIEPSSPGPIPAPGLAQPIYI 356
Query: 1146 QHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVT 1325
+ + V+EG+ L L+C V G ++ W K G + + S L V+
Sbjct: 357 E-ASSSHVAEGQSLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSR------LRLHHVS 409
Query: 1326 KADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKT 1505
AD+G+YVC+ +G + S V +P S V +
Sbjct: 410 PADSGEYVCRVVGGSGPEQEASFTVTVLPSAGSSYRLRSPV-----ISIDPPSSTVQQGQ 464
Query: 1506 TATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVA 1685
A+F + P +W+ NQ +H + + + I T ++ G YRCVA
Sbjct: 465 DASFKCLIHDGAAP----ISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVA 520
Query: 1686 FNKHGEIESNVNLQVNERKKQEKI-EGDLRAMLKKTPVLK-KGAGEEEEIDIMELLKNVD 1859
N +G +S VNL V+ + EG +R + K+ L+ AGE +
Sbjct: 521 SNAYGVAQSVVNLSVHGPPTVSVLPEGPVRVKVGKSVTLECVSAGEPR--SSARWTRIGA 578
Query: 1860 PKEYEKYARMYGITDFRGLLQ 1922
P E+ RMYG+ D +LQ
Sbjct: 579 PNNVEQ--RMYGVVDSHTVLQ 597
Score = 130 bits (328), Expect = 4e-30
Identities = 142/611 (23%), Positives = 227/611 (37%), Gaps = 38/611 (6%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G + L C + G V+W+K L PT H + + + L QV DSGEY
Sbjct: 165 VAEGQTVDLNCVVPGQAHAQVTWHKRGGSL-PT-----HHQAHGSRLRLYQVSPADSGEY 218
Query: 192 ICRAENSVGEVSSSTFLTVQ---EQKLP---PSFSRQLR----DVQETVGLPVVFECAVS 341
+CR +S + +S + ++ +P P S+ +R G + C V
Sbjct: 219 VCRVGSSSDPLEASVLVNIEASGSSAIPAPAPGGSQPIRIETSSSHVAEGQTLDLNCVVP 278
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
G V+W + G L + L + Q + +G+YSC T+ G+ +S
Sbjct: 279 GQAHAQVTWHRRGGSLPARHQVHGPL------LRLNQVSPADSGEYSCQVTSSSGTLEAS 332
Query: 522 ARLILTEGRNP----------PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNR 671
L+ E +P P + I + G+S D C V G +V W K
Sbjct: 333 V-LVTIEPSSPGPIPAPGLAQPIY-IEASSSHVAEGQSLDLNCVVPGQAHAQVTWYK--- 387
Query: 672 EIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKD-----------SCTAQL 818
GG+ + + + L + V D+G+Y C V G + S +
Sbjct: 388 ---RGGSLPARHQTHGSRLRLHHVSPADSGEYVCRVVGGSGPEQEASFTVTVLPSAGSSY 444
Query: 819 NIKERLI---PPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCE 989
++ +I PP S TV++ + SF+ G+ PIS+ W N E+
Sbjct: 445 RLRSPVISIDPP------SSTVQQGQDASFKCLIH-DGAAPISLEWKTRNQELED----N 493
Query: 990 ITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTV 1169
+ N ++ + + G Y C SN G A ++ + P V + PV V
Sbjct: 494 VHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPE--GPVRV 551
Query: 1170 SEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYV 1349
G+ + L C G +W + G R + + VL+ +DAG YV
Sbjct: 552 KVGKSVTLECVSAGEPRSSARWTRIGAPNNVEQR-MYGVVDSHTVLQISSAKPSDAGTYV 610
Query: 1350 CKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKV 1529
C A N G+ + +V G E + V TAT
Sbjct: 611 CLAQNALGTAQKRVEV---------IVDTGTVAPGAPQVQVEEAELTVEAGHTATLRCSA 661
Query: 1530 GGDPIPNVKWTKGK----WRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKH 1697
G P+P + W+K + W+ QG + I + + DSG Y C A +
Sbjct: 662 TGSPMPTIHWSKLRSPLPWQHQLQGDTLIIPR-----------VAQQDSGQYICNATSPA 710
Query: 1698 GEIESNVNLQV 1730
G E+ + L V
Sbjct: 711 GHAEATIALHV 721
Score = 115 bits (289), Expect = 1e-25
Identities = 138/611 (22%), Positives = 233/611 (38%), Gaps = 37/611 (6%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G + L C +AG P+ ++WYK L PT + + + L + + DSGEY
Sbjct: 68 VVEGQTLDLNCVVAGQPQATITWYKRGGSL-PT-----QHQAHGSRLRLHHMSVADSGEY 121
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPS-------FSRQLRDVQETVGLPVVFECAVSGSE 350
+CRA N++ +S ++V PS + G V C V G
Sbjct: 122 VCRANNNIDAQETSIMVSVSPGAGSPSVPGGAVPIRIESSSSHVAEGQTVDLNCVVPGQA 181
Query: 351 PISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSC---TATNP------- 500
V+W K G ++ T + + L ++Q + +G+Y C ++++P
Sbjct: 182 HAQVTWH------KRGGSLPTHHQAHGSRLRLYQVSPADSGEYVCRVGSSSDPLEASVLV 235
Query: 501 -IGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI 677
I ++ SSA G + P I + G++ D C V G +V W
Sbjct: 236 NIEASGSSAIPAPAPGGSQP-IRIETSSSHVAEGQTLDLNCVVPGQAHAQVTWH------ 288
Query: 678 RSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK 857
R GG+ + + L + +V D+G+Y+C + G + + I+ P
Sbjct: 289 RRGGSLPARHQVHGPLLRLNQVSPADSGEYSCQVTSSSGTLEASVLVTIEPSSPGPIPAP 348
Query: 858 KLSETV-------EETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALL 1016
L++ + EG S L V G V WYK + + +
Sbjct: 349 GLAQPIYIEASSSHVAEGQSLDLNCVVPGQAHAQVTWYKRG------GSLPARHQTHGSR 402
Query: 1017 LQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPK-------KPPVFDQHLTPVTVSE 1175
L++ S D+G Y C+V +G S V P + PV TV +
Sbjct: 403 LRLHHVSPADSGEYVCRVVGGSGPEQEASFTVTVLPSAGSSYRLRSPVISIDPPSSTVQQ 462
Query: 1176 GEFLQLSCHVR-GSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVC 1352
G+ C + G+ PI ++W +E++ + S NG +++ ++ G Y C
Sbjct: 463 GQDASFKCLIHDGAAPISLEWKTRNQELEDNVHIS---PNG-SIITIVGTRPSNHGTYRC 518
Query: 1353 KASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS-IRVVEKTTATFIAKV 1529
ASN G S ++ V G P+ +RV + T
Sbjct: 519 VASNAYGVAQSVVNLS---------------VHGPPTVSVLPEGPVRVKVGKSVTLECVS 563
Query: 1530 GGDPIPNVKWTK-GKWRQLNQG--GRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG 1700
G+P + +WT+ G + Q G + H L+I +D+G Y C+A N G
Sbjct: 564 AGEPRSSARWTRIGAPNNVEQRMYGVVDSH-----TVLQISSAKPSDAGTYVCLAQNALG 618
Query: 1701 EIESNVNLQVN 1733
+ V + V+
Sbjct: 619 TAQKRVEVIVD 629
Score = 114 bits (286), Expect = 3e-25
Identities = 135/590 (22%), Positives = 206/590 (34%), Gaps = 23/590 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G + L C + G V+W++ L A +++H L NQV DSGEY
Sbjct: 265 VAEGQTLDLNCVVPGQAHAQVTWHRRGGSL--PARHQVHG----PLLRLNQVSPADSGEY 318
Query: 192 ICRAENSVGEVSSSTFLTVQEQK--------LPPSFSRQLRDVQETVGLPVVFECAVSGS 347
C+ +S G + +S +T++ L + G + C V G
Sbjct: 319 SCQVTSSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVAEGQSLDLNCVVPGQ 378
Query: 348 EPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCT---ATNPIGSASS 518
V+W+K G L S L + + +G+Y C + P AS
Sbjct: 379 AHAQVTWYKRGGSLPARHQTHGS------RLRLHHVSPADSGEYVCRVVGGSGPEQEASF 432
Query: 519 SARLILTEGRN----PPFFDIPLAPVDAVVGESADFECHV-TGTQPIKVAWAKDNREIRS 683
+ ++ + G + P I G+ A F+C + G PI + W N+E+
Sbjct: 433 TVTVLPSAGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELED 492
Query: 684 GGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKL 863
N IS N + +TI+ + G Y C A N G L++ PP+ +
Sbjct: 493 --NVHIS--PNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHG---PPTVSVLP 545
Query: 864 SETVEETEGNSFRLEGRVAGSQPISVAWYK----NNVEIHPTANCEITFKNNALLLQVKK 1031
V G S LE AG S W + NNVE ++ +LQ+
Sbjct: 546 EGPVRVKVGKSVTLECVSAGEPRSSARWTRIGAPNNVEQRMYG-----VVDSHTVLQISS 600
Query: 1032 ASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQ---HLTPVTVSEGEFLQLSCH 1202
A DAG Y C N G+A +++ P Q +TV G L C
Sbjct: 601 AKPSDAGTYVCLAQNALGTAQKRVEVIVDTGTVAPGAPQVQVEEAELTVEAGHTATLRCS 660
Query: 1203 VRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
GS I W K + + L V + D+G Y+C A++ AG
Sbjct: 661 ATGSPMPTIHWSKLRSPLPWQHQLQGD------TLIIPRVAQQDSGQYICNATSPAGHAE 714
Query: 1383 SKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWT 1562
+ + V+ + + P+ V T G P +W+
Sbjct: 715 ATIAL---------------HVESPPYATTVPEHTSVRAGETVQLQCLAHGTPPLTFQWS 759
Query: 1563 KGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIES 1712
+ GG + L DSG YRC NK G E+
Sbjct: 760 R-------VGGSLPARATARNELLRFESVAPEDSGRYRCQVTNKVGSAEA 802
Score = 79.7 bits (195), Expect = 9e-15
Identities = 79/347 (22%), Positives = 135/347 (38%), Gaps = 14/347 (4%)
Frame = +3
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIK-------ERLIPPSFTKKLSETVE 878
+ L I +V D+G+Y C+ N G + + I+ + PP + S TV
Sbjct: 10 SRLRIPQVTPADSGEYVCHVSNGGGSQETSLIVTIEGSGPSHVPSVSPPIRIESSSPTV- 68
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
EG + L VAG ++ WYK + PT + + + L++ S+ D+G Y
Sbjct: 69 -VEGQTLDLNCVVAGQPQATITWYKRGGSL-PTQH-----QAHGSRLRLHHMSVADSGEY 121
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVT-------VSEGEFLQLSCHVRGSE 1217
C+ +N+ + + + + P P+ V+EG+ + L+C V G
Sbjct: 122 VCRANNNIDAQETSIMVSVSPGAGSPSVPGGAVPIRIESSSSHVAEGQTVDLNCVVPGQA 181
Query: 1218 PIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
++ W K G + + A+G+ L V+ AD+G+YVC+ + SD ++ V
Sbjct: 182 HAQVTWHKRGGSLPTHHQ-----AHGSR-LRLYQVSPADSGEYVCRVG--SSSDPLEASV 233
Query: 1398 TXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWR 1577
G E S V E T V G V W +
Sbjct: 234 LVNIEASGSSAIPAPAPGGSQPIRIETSSSHVAEGQTLDLNCVVPGQAHAQVTWHR---- 289
Query: 1578 QLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNV 1718
+GG + + L + + DSG Y C + G +E++V
Sbjct: 290 ---RGGSLPARHQVHGPLLRLNQVSPADSGEYSCQVTSSSGTLEASV 333
Score = 70.1 bits (170), Expect = 7e-12
Identities = 65/246 (26%), Positives = 102/246 (41%), Gaps = 8/246 (3%)
Frame = +3
Query: 1017 LQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPK--------KPPVFDQHLTPVTVS 1172
L++ + + D+G Y C VSN GS TS IV E PP+ + +P TV
Sbjct: 12 LRIPQVTPADSGEYVCHVSNGGGSQE-TSLIVTIEGSGPSHVPSVSPPIRIESSSP-TVV 69
Query: 1173 EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVC 1352
EG+ L L+C V G I W K G + + A+G+ L ++ AD+G+YVC
Sbjct: 70 EGQTLDLNCVVAGQPQATITWYKRGGSLPTQHQ-----AHGSR-LRLHHMSVADSGEYVC 123
Query: 1353 KASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVG 1532
+A+N + + V+ G + E S V E T V
Sbjct: 124 RANNNIDAQETSIMVSVSPGAGSPSVP-----GGAVPIRIESSSSHVAEGQTVDLNCVVP 178
Query: 1533 GDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIES 1712
G V W K +GG + H + ++L + + DSG Y C + +E+
Sbjct: 179 GQAHAQVTWHK-------RGGSLPTHHQAHGSRLRLYQVSPADSGEYVCRVGSSSDPLEA 231
Query: 1713 NVNLQV 1730
+V + +
Sbjct: 232 SVLVNI 237
>ref|XP_546425.2| PREDICTED: similar to roundabout, axon guidance receptor, homolog 3
[Canis familiaris].
Length = 1385
Score = 147 bits (370), Expect = 5e-35
Identities = 129/481 (26%), Positives = 201/481 (41%), Gaps = 21/481 (4%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVAT-------LVFNQVD 170
V+ G+ A+L C+ G P + WYK ++ R + + +V +
Sbjct: 75 VSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGALFFPRIVHGRRA 134
Query: 171 SNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
D G Y C A N +G +S +++ L F + +V VG P V EC
Sbjct: 135 RPDEGVYTCVARNYLGAAASRN-ASLEVAVLRDDFRQSPGNVVVAVGEPAVMECVPPRGH 193
Query: 351 P-ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGS-ASSSA 524
P SVSW KD L++ T L + T +S AG Y C A+N G S +A
Sbjct: 194 PEPSVSWKKDSARLREEEGRITI---RGGKLMMSHTLKSDAGMYVCVASNMAGERESGAA 250
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
L++ E P F P+ V + DF C V G P ++ W K++ E+ + G Y+I
Sbjct: 251 ELVVLE--RPSFLRRPVNQV-VLADAPVDFPCEVQGDPPPRLRWRKEDGELPT-GRYEI- 305
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
+ L I +V D G YTC A N VG+ + L++ +PP + + +
Sbjct: 306 --RSDHSLWIGRVTAADEGTYTCVAENSVGRAEASGSLSVH---VPPQLVTQPQDQM-AA 359
Query: 885 EGNSFRLEGRVAGSQPISVAWYKNNVEI--------HPTANCEITFKNNALLLQVKKASM 1040
G S + G+ P ++ W K ++ P ++ + L +
Sbjct: 360 PGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQPLQPKGRFSVSPRGQ---LNITDVQS 416
Query: 1041 GDAGLYTCKVSNDAGSALCTSSIVIKEPKK----PPVFDQHLTPVTVSEGEFLQLSCHVR 1208
GDAG Y C+ + AGS L + + +K PP+ Q T++ G + L C V
Sbjct: 417 GDAGYYVCQAVSVAGSVLAKALLEVKRASSLDGLPPIILQGPANQTLALGSPVWLPCRVT 476
Query: 1209 GSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSK 1388
G+ ++W K G+ ++ D ANGT L V + D G Y C A + G T
Sbjct: 477 GNPQPSVRWKKDGQWLQGDDLQLNLMANGT--LYIASVQEMDLGFYSCVAKSSMGEATWS 534
Query: 1389 S 1391
S
Sbjct: 535 S 535
Score = 122 bits (305), Expect = 2e-27
Identities = 135/507 (26%), Positives = 208/507 (41%), Gaps = 21/507 (4%)
Frame = +3
Query: 246 VQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPL---KDGPNIQTS 416
V+ + P Q D+ + G P C G ++ W+K+G + ++ P
Sbjct: 57 VEPEDAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRL 116
Query: 417 FLDNVAT----LNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPV 584
L + A + + R G Y+C A N +G+A+S + F P V
Sbjct: 117 LLPSGALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSP-GNV 175
Query: 585 DAVVGESADFECHVTGTQPI-KVAWAKDNREIRSG-GNYQISYLENSAHLTILKVDKGDT 758
VGE A EC P V+W KD+ +R G I L + K D
Sbjct: 176 VVAVGEPAVMECVPPRGHPEPSVSWKKDSARLREEEGRITI----RGGKLMMSHTLKSDA 231
Query: 759 GQYTCYAVNEVG-KDSCTAQLNIKERLIPPSFTKK-LSETVEETEGNSFRLEGRVAGSQP 932
G Y C A N G ++S A+L + ER PSF ++ +++ V F E V G P
Sbjct: 232 GMYVCVASNMAGERESGAAELVVLER---PSFLRRPVNQVVLADAPVDFPCE--VQGDPP 286
Query: 933 ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIV 1112
+ W K + E+ PT EI ++ L + + + D G YTC N G A + S+
Sbjct: 287 PRLRWRKEDGEL-PTGRYEIRSDHS---LWIGRVTAADEGTYTCVAENSVGRAEASGSLS 342
Query: 1113 IKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI--------KPSD 1268
+ P P + Q + + GE + C +G+ P I W K G ++ +P
Sbjct: 343 VHVP--PQLVTQPQDQMA-APGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQPLQPKG 399
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
R S S L DV DAG YVC+A +VAGS +K+ + +
Sbjct: 400 RFSVS---PRGQLNITDVQSGDAGYYVCQAVSVAGSVLAKALL---------EVKRASSL 447
Query: 1449 DG-KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQLNQGGRIFIHQKGD 1622
DG + P + + + +V G+P P+V+W K G+W QG + ++ +
Sbjct: 448 DGLPPIILQGPANQTLALGSPVWLPCRVTGNPQPSVRWKKDGQWL---QGDDLQLNLMAN 504
Query: 1623 EAKLEIRDTTKTDSG T
Sbjct: 4042 ASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDR--------- 4092
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
D FF +++ V T K+ G V W K +++ R I
Sbjct: 4093 ---DIAPFFTKPLRNVDSVVSGTCRLDCKIAGSLPMRVSWFK-DGKEVTSSDRYRIAFVE 4148
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A LEI +D+G + C A N G + + L V E
Sbjct: 4149 GTASLEISRVDMSDAGNFTCRATNSVGSKDCSGALIVQE 4187
Score = 259 bits (662), Expect = 6e-69
Identities = 172/581 (29%), Positives = 257/581 (44%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++V +G A C++ P + W+K ++ + + N V TL + D
Sbjct: 3447 PLEVALGHLAKFTCEIHSAPNVRFQWFKAGREIYESDKCSIRSANYVTTLEILRTQVVDC 3506
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+A N G VS + LTV E PP+F + + V VG F C V+G+ I
Sbjct: 3507 GEYTCKASNEYGSVSCTATLTVTEA-YPPTFFSRPKSVTTFVGKAAKFLCTVTGTPVIET 3565
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W KDG L P + S +DN L + G YSC A+N G+ + A L + +
Sbjct: 3566 IWQKDGMALSPSPTCKISDVDNKHILELSNLTVHDKGVYSCKASNKFGADTCQAELDIID 3625
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L PV + + + E V + + + W+K+ +++ G +Y+I + + A
Sbjct: 3626 ---KPHFIKELEPVQSAINKKIHLEGQVDEDRKVTITWSKNGQKLPPGKDYKIYFEDKIA 3682
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I D+G Y C A NE G S +A + I+E PPSF KK+ + G S R
Sbjct: 3683 SLEIPLAKLKDSGTYVCTASNEAGSSSTSATVTIRE---PPSFVKKVDPSYLMLPGESAR 3739
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L R+ GS I V W+KNN E+ + ++F N+ +L + + D+G Y+C+ ND
Sbjct: 3740 LHCRLKGSPVIQVTWFKNNKELTESNTIRMSFVNSEAVLDITDVKVEDSGTYSCEAVNDV 3799
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GS C++ IV+KE PP F + L P + G L C + G+ P I W K ++I+
Sbjct: 3800 GSDSCSAEIVVKE---PPSFIKTLEPADIVRGTNALLQCEIAGTGPFEISWFKDKKQIRS 3856
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + T LE AD GDY C +N G
Sbjct: 3857 SKKYRLFSQKSTVSLEIFSFNSADVGDYECVVANEVGK---------------CGCVATH 3901
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+ FV + + T T A V G +V W KG+ + + G+I +
Sbjct: 3902 LLKEPPTFVKKVDDFTALAGQTVTLQAAVRGSEPISVTWMKGQ-EIIKEDGKIKMSFANG 3960
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
A L I D + Y C+A N+ G S L V E K
Sbjct: 3961 VAVLIIPDVQISFGDKYTCLAENEAGSQTSVGELIVKEPAK 4001
Score = 220 bits (560), Expect = 4e-57
Identities = 159/600 (26%), Positives = 255/600 (42%), Gaps = 22/600 (3%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ V G A ++G P+ +SWYK + L K TL+ + D+
Sbjct: 3234 PITVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDA 3293
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKL----------PPSFSRQLRDVQETVGLPVVFEC 332
Y C A N G ++S L+V+ ++ PP+ L+D + G P F+C
Sbjct: 3294 AVYTCEARNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIVSPLQDAVTSEGRPAHFQC 3353
Query: 333 AVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSA 512
VSG++ + VSW+ + +K + + ++ L + + G Y+ A+N +G
Sbjct: 3354 RVSGTD-LKVSWYSKDKKIKPSRFFKMTQFEDTYQLEVAEAFPEDEGIYTFVASNAVGQV 3412
Query: 513 SSSARLILT------------EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAW 656
SS+A L L E + P + P++ +G A F C + ++ W
Sbjct: 3413 SSTATLRLEAPEAMLHEQIEMEMKAAPVIRRRIEPLEVALGHLAKFTCEIHSAPNVRFQW 3472
Query: 657 AKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERL 836
K REI I L IL+ D G+YTC A NE G SCTA L + E
Sbjct: 3473 FKAGREIYESDKCSIRSANYVTTLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAY 3532
Query: 837 IPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALL 1016
P F++ S T G + + V G+ I W K+ + + P+ C+I+ +N +
Sbjct: 3533 PPTFFSRPKSVTT--FVGKAAKFLCTVTGTPVIETIWQKDGMALSPSPTCKISDVDNKHI 3590
Query: 1017 LQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLS 1196
L++ ++ D G+Y+CK SN G+ C + + I + P F + L PV + + + L
Sbjct: 3591 LELSNLTVHDKGVYSCKASNKFGADTCQAELDIIDK---PHFIKELEPVQSAINKKIHLE 3647
Query: 1197 CHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGS 1376
V + I W K G+++ P F + A LE D+G YVC ASN AGS
Sbjct: 3648 GQVDEDRKVTITWSKNGQKLPPGKDYKIYFEDKIASLEIPLAKLKDSGTYVCTASNEAGS 3707
Query: 1377 DTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVK 1556
++ + VT + F S ++ +A ++ G P+ V
Sbjct: 3708 SSTSATVTIR--------------EPPSFVKKVDPSYLMLPGESARLHCRLKGSPVIQVT 3753
Query: 1557 WTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
W K ++L + I + EA L+I D DSG Y C A N G + + V E
Sbjct: 3754 WFKNN-KELTESNTIRMSFVNSEAVLDITDVKVEDSGTYSCEAVNDVGSDSCSAEIVVKE 3812
Score = 181 bits (459), Expect = 2e-45
Identities = 156/636 (24%), Positives = 272/636 (42%), Gaps = 26/636 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+KV A +C+++ P+I V W K +L+ K+ V L+ +D+G
Sbjct: 3054 IKVLEKKRAMFECEVS-EPDITVQWMKDGQELQLVDRIKIQKEKYVHRLLIPSTRMSDAG 3112
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y A G +SS+ S R+++ +++ + V FE + +
Sbjct: 3113 KYTVVAG---GNMSSANLFVEGRDVRIRSIKREVQVIEKQRAV-VEFEV---NEDDVDAH 3165
Query: 366 WFKDGRPLKDGPNIQTSFL--DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
W+KDG + + ++ + + I +T S AG+Y+ A G SS L +
Sbjct: 3166 WYKDGIEINFQVQERHQYVVERRIHRMFISETRHSDAGEYTFVA----GRNRSSVTLYVN 3221
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
PP L P+ G+ A F ++G K++W K+ + + +G ++ +L +
Sbjct: 3222 -APEPPQILQELQPITVQSGKPARFCAVISGRPQPKISWYKEEQLLSTG--FKCKFLHDG 3278
Query: 720 AHLTILKVDK--GDTGQYTCYAVNEVGKDSCTAQLNIKERLI----------PPSFTKKL 863
T+L ++ D YTC A N+ G + +A L+++ + PP+ L
Sbjct: 3279 QEYTLLLIEAFPEDAAVYTCEARNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIVSPL 3338
Query: 864 SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMG 1043
+ V +EG + RV+G+ + V+WY + +I P+ ++T + L+V +A
Sbjct: 3339 QDAVT-SEGRPAHFQCRVSGTD-LKVSWYSKDKKIKPSRFFKMTQFEDTYQLEVAEAFPE 3396
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEP------------KKPPVFDQHLTPVTVSEGEFL 1187
D G+YT SN G T+++ ++ P K PV + + P+ V+ G
Sbjct: 3397 DEGIYTFVASNAVGQVSSTATLRLEAPEAMLHEQIEMEMKAAPVIRRRIEPLEVALGHLA 3456
Query: 1188 QLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNV 1367
+ +C + + +R QW KAGREI SD+CS AN LE D G+Y CKASN
Sbjct: 3457 KFTCEIHSAPNVRFQWFKAGREIYESDKCSIRSANYVTTLEILRTQVVDCGEYTCKASNE 3516
Query: 1368 AGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIP 1547
GS + + +T F S P+S+ A F+ V G P+
Sbjct: 3517 YGSVSCTATLTVTEAYPPT-------------FFSRPKSVTTFVGKAAKFLCTVTGTPVI 3563
Query: 1548 NVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
W K L+ I ++ LE+ + T D G+Y C A NK G L
Sbjct: 3564 ETIWQK-DGMALSPSPTCKISDVDNKHILELSNLTVHDKGVYSCKASNKFGADTCQAELD 3622
Query: 1728 VNERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEIDI 1835
+ ++ K +++ + K L+ E+ ++ I
Sbjct: 3623 IIDKPHFIKELEPVQSAINKKIHLEGQVDEDRKVTI 3658
Score = 129 bits (325), Expect = 7e-30
Identities = 128/463 (27%), Positives = 202/463 (43%), Gaps = 4/463 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKL-RPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
G A + ++ G P+ WYK K+ R Y +NV LV V + DS +
Sbjct: 2079 GSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMV 2138
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRD-VQETVGLPVVFECAVSGSEP-ISVSWF 371
+A N GE SS FL VQ ++L +F+++L+D V + FEC SEP + V W+
Sbjct: 2139 KAINIAGETSSHAFLLVQAKQL-ITFTQELQDVVAKEKDTMATFECET--SEPFVKVKWY 2195
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDG + G + V L++ D S A YSC + ++A+LI+ EG
Sbjct: 2196 KDGVEIHTGDKYRMHSDRKVHFLSVLMIDTSDAEDYSCVLVED-ENVKTTAKLIV-EGAV 2253
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
F L ++ S + EC +T + I+ W E++S G Y I+ +LT
Sbjct: 2254 VEFVK-ELQDIEVPESFSGELECIIT-PENIEGKWYHKGVELKSNGKYTITSRRGRQNLT 2311
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
+ V K D G+Y+ + V+ GK + T +L +K R P + + LS+ + EG+ +LE
Sbjct: 2312 VKDVTKEDQGEYS-FVVD--GKKT-TCKLKMKPR--PIAILQGLSDQ-KVCEGDIVQLEV 2364
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
+V+ + + W K+ E+ P I + +L ++ + DAG Y+ + + S
Sbjct: 2365 KVS-LENVEGVWMKDGEEVQPGDRVHIVIDKQSHMLLIEDMTKEDAGHYSFTIPSLGLST 2423
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
S+ + P L V V EG L C V + ++W +IKP DR
Sbjct: 2424 HGRVSVYSVDVITP------LKDVNVLEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR 2477
Query: 1272 CSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGS-DTSKSKV 1397
L +D G Y V S D S K+
Sbjct: 2478 VHAIVKGTKQRLVINRTHASDEGPYKLVVGRVETSCDLSVEKI 2520
Score = 127 bits (318), Expect = 5e-29
Identities = 155/637 (24%), Positives = 259/637 (40%), Gaps = 28/637 (4%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV + G+ L C + G+ I + W K +++P+ F N A L V D+
Sbjct: 8337 PVTASEGEFVQLSCHVWGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLELKDVTKADA 8396
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLP-PSFSRQLRD-----VQETVGLPVVFECAVS- 341
G+Y+C+A N G +S + +T++++ P+ + D V E + VV + +
Sbjct: 8397 GDYVCKASNVAGSDTSKSKVTIKDKPAAVPAAKKAAVDGKLFFVSEPQSIRVVEKTTATF 8456
Query: 342 ----GSEPI-SVSWFKDG-RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPI 503
G +PI +V W K R L G I + A L I T ++ +G Y C A N
Sbjct: 8457 IAKVGGDPIPNVKWTKGKWRQLNQGGRILIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKH 8516
Query: 504 GSASSSARLILTEGRNPPFFDIPLAPV---DAVVGESADFECHVTGTQPIKVAWAKD-NR 671
G S+ L + E + + L + V+ + A E + + +K K+ +
Sbjct: 8517 GEIESNVNLQVDERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEIDIMELLKNVDPKEYEK 8576
Query: 672 EIRSGGNYQISYLENSAHLTILKVDKGD-TGQYTCYAVNEVGKDSCTAQ---LNIKERLI 839
R G L + L LK +G+ T + + + KD + I++RL
Sbjct: 8577 YARMYGITDFRGLLQAFEL--LKQTEGEETHRLEIEEIEKSEKDEKEFEELVSFIQQRLS 8634
Query: 840 ---PPSFTKKL-SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNN 1007
P + K + ++TV + F ++ ++ + I ++WYK ++ P+ EI+ +
Sbjct: 8635 QTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPE-IKLSWYKGTEKLEPSDKFEISIDGD 8693
Query: 1008 ALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFL 1187
L+VK + D G Y SA T VI+ P +++HL VT+ EG+
Sbjct: 8694 RHTLRVKNCQLKDQGNYRLVCGPHIASAKLT---VIE-----PAWERHLQDVTLKEGQTC 8745
Query: 1188 QLSCHVRGSEP-IRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASN 1364
++C S P +R +W + GR +KP R + L DV D G Y CK +
Sbjct: 8746 TMTCQF--SVPNVRSEWFRNGRILKPQGRYKTEVEHKVHKLTIADVRAEDQGRYTCKHED 8803
Query: 1365 VAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPI 1544
+ S + + + F Q+I V E +ATF +V D
Sbjct: 8804 LETSAELRIEAE------------------PIQFTKRIQNIVVSEHQSATFECEVSFDD- 8844
Query: 1545 PNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVA-FNKHGEIESNVN 1721
V W KG +L + + G + I + T D G+Y +A GE S
Sbjct: 8845 AIVTWYKGP-TELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAE 8903
Query: 1722 LQVNERK-KQEKIEGDLRAMLKKTPVLKKGAGEEEEI 1829
L + ++ K E D+ P + A EEI
Sbjct: 8904 LYLTTKEIKLEMKPPDIPDSRVPIPTMPIRAIPPEEI 8940
Score = 122 bits (305), Expect = 2e-27
Identities = 150/600 (25%), Positives = 239/600 (39%), Gaps = 14/600 (2%)
Frame = +3
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-------GLPVVFECAVSGSEPISV 362
+ ++ E T T + K+ S S + + E + G F V G
Sbjct: 2037 KKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC 2096
Query: 363 SWFKDGRPLKDGPNIQTSFL-DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
W+K+G ++ I + DNV L I + A N G SS A +L
Sbjct: 2097 EWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHA-FLLV 2155
Query: 540 EGRNPPFFDIPLAPVDAVVGES-ADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
+ + F L V A ++ A FEC T +KV W KD EI +G Y++
Sbjct: 2156 QAKQLITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGVEIHTGDKYRMHSDRK 2214
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
L++L +D D Y+C V + + TA+L ++ ++ F K+L + +E E S
Sbjct: 2215 VHFLSVLMIDTSDAEDYSCVLVEDENVKT-TAKLIVEGAVV--EFVKELQD-IEVPESFS 2270
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
LE + + I WY VE+ IT + L VK + D G Y+ V
Sbjct: 2271 GELE-CIITPENIEGKWYHKGVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVV-- 2327
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
D C +K +P Q L+ V EG+ +QL V E + W+K G E+
Sbjct: 2328 DGKKTTCK----LKMKPRPIAILQGLSDQKVCEGDIVQLEVKV-SLENVEGVWMKDGEEV 2382
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
+P DR + +L +D+TK DAG Y ++ S + V
Sbjct: 2383 QPGDRVHIVIDKQSHMLLIEDMTKEDAGHYSFTIPSLGLSTHGRVSV------------- 2429
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
VD ++ + + V+E T A KV + +VKW Q+ R+ K
Sbjct: 2430 -YSVD----VITPLKDVNVLEGTKAVLECKVSVPDVTSVKWYLND-EQIKPDDRVHAIVK 2483
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPV 1796
G + +L I T +D G Y+ V G +E++ +L V + K + DL + V
Sbjct: 2484 GTKQRLVINRTHASDEGPYKLVV----GRVETSCDLSVEKIKIIRGLR-DLTCTETQNVV 2538
Query: 1797 LKKGAGEEEEIDIMELLKNVDPKEYEKY-----ARMYGITDFRGLLQAFEMLKQSQEEET 1961
L+ ID++ K+ + K KY ++Y +T M+K + E T
Sbjct: 2539 LEVEL-SHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLT-------VLNMMKDDEGEYT 2590
Score = 112 bits (280), Expect = 1e-24
Identities = 112/507 (22%), Positives = 184/507 (36%), Gaps = 48/507 (9%)
Frame = +3
Query: 24 DSASLQCQLAGTPEIG--VSWYKGDTKLRPTATYKMHFR-NNVATLVFNQVDSNDSGEYI 194
D A L C + + V+WYK +L+ ++ H+ + L + +D GEY+
Sbjct: 32757 DIAKLTCVVESSALCAKEVTWYKDGRRLKENGHFQFHYSADGTYELKILNLAESDRGEYV 32816
Query: 195 CRAENSVGEVSSS------TFLTVQEQ---------------------------KLPPSF 275
C G ++ F ++ EQ K P
Sbjct: 32817 CEVSGEGGTSKTNFQFVGQAFKSIHEQVSSISETKKAKAAPKTAEPTETKKTEPKAPAPI 32876
Query: 276 SRQ------LRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVAT 437
S + L+D + F V+G +V W KDG+ + G + S
Sbjct: 32877 STKPVIVTGLQDTTVSSDSVAKFAVKVTGEPQPTVIWTKDGKAISQGGKYKLSEDKGAFF 32936
Query: 438 LNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGE----- 602
L I +TD S +G Y+CT TN GS SSS +L + + + + +
Sbjct: 32937 LEIHKTDTSDSGLYTCTITNSAGSVSSSCKLTIKVVEDTEIQKVSAQKTSEITSQKKASV 32996
Query: 603 SADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAV 782
+ ++ IK + K + ++ E S L KV K + V
Sbjct: 32997 QEEISKKALISEEIKTSEVKSHEKLALKE-------EASTVLISEKVKKSEAASLEKSVV 33049
Query: 783 NEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNV 962
+E T E + + K S + T G L+ +AG+ V W N V
Sbjct: 33050 HE----EITKTSQASEEIRTHAEIKAFSTQMSITAGQKVTLKANIAGA--TDVKWVLNGV 33103
Query: 963 EIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVI-KEPKKPPV 1139
E+ + + L +++A D G+ TC G C + + KE P
Sbjct: 33104 ELSNSDEYRYGISGSDQTLTIRQAGHKDEGILTCIGKTSQGIIKCQYDLTLSKELSDAPA 33163
Query: 1140 FDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKD 1319
F V+EG+ + SC + G I+W K I S S S + LE ++
Sbjct: 33164 FISQPRSQNVNEGQNVLFSCEISGEPSPEIEWFKNNLPISISSNISVSRSRNVYSLEIRN 33223
Query: 1320 VTKADAGDYVCKASNVAGSDTSKSKVT 1400
+ +D+G Y KA N G ++ + +T
Sbjct: 33224 ASVSDSGKYTIKAKNFHGQCSATASLT 33250
Score = 111 bits (277), Expect = 3e-24
Identities = 114/502 (22%), Positives = 197/502 (39%), Gaps = 45/502 (8%)
Frame = +3
Query: 360 VSWFKDGRPLKDGPNIQTSF-LDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI- 533
V+W+KDGR LK+ + Q + D L I S G+Y C + G++ ++ + +
Sbjct: 32775 VTWYKDGRRLKENGHFQFHYSADGTYELKILNLAESDRGEYVCEVSGEGGTSKTNFQFVG 32834
Query: 534 --------------------------------LTEGRNPPFFDIPLAPV------DAVVG 599
TE + P I PV D V
Sbjct: 32835 QAFKSIHEQVSSISETKKAKAAPKTAEPTETKKTEPKAPA--PISTKPVIVTGLQDTTVS 32892
Query: 600 ES--ADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTC 773
A F VTG V W KD + I GG Y++S + + L I K D D+G YTC
Sbjct: 32893 SDSVAKFAVKVTGEPQPTVIWTKDGKAISQGGKYKLSEDKGAFFLEIHKTDTSDSGLYTC 32952
Query: 774 YAVNEVGKDSCTAQLNIKERLIPPSFTKKLS--ETVEETEGNSFRLEGRVAGSQPISVAW 947
N G S + +L IK ++ + +K+S +T E T ++ ++ IS
Sbjct: 32953 TITNSAGSVSSSCKLTIK--VVEDTEIQKVSAQKTSEITSQKKASVQEEISKKALISEEI 33010
Query: 948 YKNNVEIHPTANCEITFKNNA-LLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEP 1124
+ V+ H ++ K A +L +K +A V ++ + +S I+
Sbjct: 33011 KTSEVKSHE----KLALKEEASTVLISEKVKKSEAASLEKSVVHEEITKTSQASEEIRTH 33066
Query: 1125 KKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAV 1304
+ F T ++++ G+ + L ++ G+ ++ W+ G E+ SD + +
Sbjct: 33067 AEIKAFS---TQMSITAGQKVTLKANIAGATDVK--WVLNGVELSNSDEYRYGISGSDQT 33121
Query: 1305 LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS 1484
L + D G C G + +T + F+S+P+S
Sbjct: 33122 LTIRQAGHKDEGILTCIGKTSQGIIKCQYDLT-----------LSKELSDAPAFISQPRS 33170
Query: 1485 IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDS 1664
V E F ++ G+P P ++W K ++ I + + + LEIR+ + +DS
Sbjct: 33171 QNVNEGQNVLFSCEISGEPSPEIEWFKNN-LPISISSNISVSRSRNVYSLEIRNASVSDS 33229
Query: 1665 GLYRCVAFNKHGEIESNVNLQV 1730
G Y A N HG+ + +L V
Sbjct: 33230 GKYTIKAKNFHGQCSATASLTV 33251
Score = 110 bits (276), Expect = 4e-24
Identities = 136/560 (24%), Positives = 225/560 (40%), Gaps = 4/560 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+V ++A + +++ +I +W L T ++ L+ + + +G
Sbjct: 12133 VEVMETETARFETEIS-EDDIHANWKLKGEALLQTPECEIKEEGKTHFLILHNCRLDQTG 12191
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+A N V SS L V+ + + R L+D+ T G F+C +S E I V
Sbjct: 12192 GVDFQAAN----VKSSAHLRVKPRVI--GLLRPLKDITVTAGETATFDCELS-YEDIPVE 12244
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+ G+ L+ + V TL + AG+ A + + A+L + E
Sbjct: 12245 WYLRGKKLEPSDKVVMRSEGRVHTLTLRDVKLEDAGEVQLVAKD----FKTQAKLFVKEP 12300
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P F PL +A EC V+ + KV W K+ EI Y+I
Sbjct: 12301 --PVEFTKPLEDQTVEEEATAVLECEVS-RENAKVKWFKNGTEILKSKKYEIVADGRVRK 12357
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPP--SFTKKLSET-VEETEGNS 896
L I D YTC A + K SC LN+ +PP F + L++ V+E E
Sbjct: 12358 LIIHGCTPEDIKTYTCDAKDF--KTSCN--LNV----VPPHVEFLRPLTDLRVKEKEMAR 12409
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
F E + V W+K+ EI +I K +L + K + D Y+C+V
Sbjct: 12410 FECE---ISRENAKVHWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRT 12466
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEP-IRIQWLKAGRE 1253
S + T V++E VF ++L + VSE + ++L C V S+P + W K E
Sbjct: 12467 ARTSGMLT---VLEE---EAVFTKNLANIEVSETDTVKLVCEV--SKPGAEVTWYKGDEE 12518
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
I + R +L ++ DAG+Y C+ S + KV
Sbjct: 12519 IIETGRYEILTDGRKRILIIQNAHLEDAGNYNCRLP----SSRTDGKVKVHELAAE---- 12570
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
F+S+PQ++ ++E A F+ + + V+W + + L G + +
Sbjct: 12571 ----------FISKPQNLEILEGEKAEFVCSISKENF-EVQWKRDD-KTLESGDKYDVIA 12618
Query: 1614 KGDEAKLEIRDTTKTDSGLY 1673
G + L ++D T D G Y
Sbjct: 12619 DGKKRVLVVKDATLQDMGTY 12638
Score = 110 bits (274), Expect = 6e-24
Identities = 147/679 (21%), Positives = 251/679 (36%), Gaps = 54/679 (7%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSN--DS 182
+V G + + P V WY +L+ ++ K+H+ N L +D + DS
Sbjct: 32408 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTLEILDCHIDDS 32465
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y N GE S L V +++ Q RD Q +P ++ +E +V
Sbjct: 32466 GTYRAVCTNYKGEASDYATLDVTGGDYT-TYASQRRDEQ----VPRSVFPELTRTEAYAV 32520
Query: 363 SWFKDGRPLKDGPNIQ---TSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL- 530
S FK ++ +++ + + +L+ ++ S + + + S+ ++
Sbjct: 32521 SSFKKTSEMEASSSVREMKSLMTETRESLSSYEHHASAEMKSAAIEEKSLEEKSTHRKIK 32580
Query: 531 ------ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
ILT+ R+ ++ GESA F C G V W + + I +
Sbjct: 32581 TTLAARILTKPRSITVYE----------GESARFSCDTDGEPVPTVTWLRGGQVISTSAR 32630
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLI------PPSFT 854
+Q++ + + I V D G Y+ N G+ L +++ + P
Sbjct: 32631 HQVTTSKYKSTFEISSVQASDEGNYSVVVENSDGRQEAQFTLTVQKARVTEKAVTSPPRV 32690
Query: 855 KKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKA 1034
K V+ EG + RV +P++ HP A
Sbjct: 32691 KSPEPRVKSPEG--AKSPKRVKSPEPVTP---------HPKA------------------ 32721
Query: 1035 SMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGS 1214
V T + K PP Q L + + +L+C V S
Sbjct: 32722 -----------VPPTETKPTPTEKVQQKPVAAPPKIIQSLK--AEASKDIAKLTCVVESS 32768
Query: 1215 E--PIRIQWLKAGREIKPSDRCSFSF-ANGTAVLEFKDVTKADAGDYVCKASNVAG---- 1373
+ W K GR +K + F + A+GT L+ ++ ++D G+YVC+ S G
Sbjct: 32769 ALCAKEVTWYKDGRRLKENGHFQFHYSADGTYELKILNLAESDRGEYVCEVSGEGGTSKT 32828
Query: 1374 -------------------SDTSKS----KVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS 1484
S+T K+ K + K V+ Q
Sbjct: 32829 NFQFVGQAFKSIHEQVSSISETKKAKAAPKTAEPTETKKTEPKAPAPISTKPVIVTGLQD 32888
Query: 1485 IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDS 1664
V + A F KV G+P P V WTK + ++QGG+ + + LEI T +DS
Sbjct: 32889 TTVSSDSVAKFAVKVTGEPQPTVIWTK-DGKAISQGGKYKLSEDKGAFFLEIHKTDTSDS 32947
Query: 1665 GLYRCVAFNKHGEIESN--VNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEID-- 1832
GLY C N G + S+ + ++V E + +K+ + + +K A +EEI
Sbjct: 32948 GLYTCTITNSAGSVSSSCKLTIKVVEDTEIQKVSAQKTSEITS----QKKASVQEEISKK 33003
Query: 1833 --IMELLKNVDPKEYEKYA 1883
I E +K + K +EK A
Sbjct: 33004 ALISEEIKTSEVKSHEKLA 33022
Score = 109 bits (273), Expect = 8e-24
Identities = 71/220 (32%), Positives = 111/220 (50%), Gaps = 3/220 (1%)
Frame = +3
Query: 267 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDG--PNIQTSFLDNVATL 440
P+F++ L+ V G FE +SG VSWF+DG+ + P +Q SF D A L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 441 NIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFEC 620
I ++ +G+YS ATN G A+S+A L++T PP F L + G +
Sbjct: 66 TIPAVTKANSGRYSLRATNGSGQATSTAELLVTAETAPPNFTQRLQSMTVRQGSQVRLQV 125
Query: 621 HVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKD 800
VTG V + +D EI+S ++QIS L I + D+G Y+ A N VG+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQISQEGELYSLLIAEAYPEDSGTYSVNATNSVGRA 185
Query: 801 SCTAQLNIK-ERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+ TA+L ++ E ++P TK + T + +E R+E ++
Sbjct: 186 TSTAELLVQGEEVVPAKRTKTIVSTAQISETRQTRIEKKI 225
Score = 109 bits (273), Expect = 8e-24
Identities = 136/592 (22%), Positives = 224/592 (37%), Gaps = 4/592 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++V+ D+ L C+++ P V+WYKGD ++ T Y++ L+ D+G
Sbjct: 12489 IEVSETDTVKLVCEVS-KPGAEVTWYKGDEEIIETGRYEILTDGRKRILIIQNAHLEDAG 12547
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y CR SS T V+ +L F + ++++ G F C++S E V
Sbjct: 12548 NYNCRLP------SSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSIS-KENFEVQ 12600
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W +D + L+ G L + G Y +G+A ++A L + E
Sbjct: 12601 WKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTVIEK 12656
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
+PL + F C V T+ K W +++ I Y I +
Sbjct: 12657 LR---IIVPLKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNDEAIFDSSKYIILQKDLVYT 12712
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKD-SCTAQLNIKE---RLIPPSFTKKLSETVEETEGN 893
L I D Y N G++ A L ++E R+I P K ET+E+
Sbjct: 12713 LRIRNAQLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIIEP---LKDIETMEKKSVT 12769
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
+ R+ +++ W KN E+ L +K D G Y
Sbjct: 12770 FWCKVNRL----NVTLKWTKNGEEVAFDNRVLYRIDKYKHSLIIKDCGFPDEGEYVVTAG 12825
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
D A ++I+ P + F +HL TV+E + SC + E ++W + GRE
Sbjct: 12826 QDKSVA---ELLIIEAPTE---FVEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGRE 12878
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
IK + F L KD D +Y C G D KS+
Sbjct: 12879 IKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC------GVDDRKSRARLFVE------- 12925
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
+ + + PQ I F+A++ D + V+W K + QG + +
Sbjct: 12926 -----EIPVEIIRPPQDILEAPGADVVFLAELNKDKV-EVQWLKNN-MIIVQGDKHQMMS 12978
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDL 1769
+G +L+I D D G YR +A +K E+ L++ K + + DL
Sbjct: 12979 EGKIHRLQICDIKPRDQGEYRFIAKDK----EARAKLELAAAPKIKTADQDL 13026
Score = 107 bits (267), Expect = 4e-23
Identities = 165/757 (21%), Positives = 279/757 (36%), Gaps = 138/757 (18%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G+S +L+C ++G P V+WY+ D ++ + +++ F++ +A L+ + + DSG
Sbjct: 949 VTVIEGESVTLECHISGYPSPKVTWYREDYQIESSIDFQITFQSGIARLLIREAFAEDSG 1008
Query: 186 EYICRAENSVGEVSSSTFLTVQ------------EQKLPPSFSR--QLRDVQET------ 305
+ C A N G VS+S +L VQ +K+ R + RDV T
Sbjct: 1009 RFTCTAVNEAGTVSTSCYLAVQVSEEFEKETTAVAEKITTEEKRFVESRDVVMTDTSITE 1068
Query: 306 -----------------------VGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTS 416
G +VFEC V G+ V W K G PL G + S
Sbjct: 1069 EHAGPGEPAAPFFITKPVVQKLVEGGSIVFECQVGGNPKPHVYWKKSGVPLTSGYRYKVS 1128
Query: 417 FLDNV--ATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI-------LTEGRNPPFFDI 569
+ L I T AG+Y+ N G S+SA L+ L + + +
Sbjct: 1129 YNKQTGECRLVISMTFADDAGEYTIVIRNKHGETSASASLLEEADYESLMKSQQEMLYQT 1188
Query: 570 PLAPV--DAVVGESA------DFECHVTGTQP-IKVAWAKDNREIRSGGNYQISYLENSA 722
+ + VGE A ++E Q I+ AKD +R+ Q ++ +
Sbjct: 1189 QVTAFVQEPKVGEIAPGYVYSEYEKEYEKEQALIRKKMAKDTVMVRTFVEDQEFHISSFE 1248
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
I +++ + E G++ ++ E I F ++ + EG
Sbjct: 1249 ERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESE-AIEAGFDLRV-KNYRILEGMGVT 1306
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITF-KNNALLLQVKKASMGDAGLYTCKVSND 1079
+++G +AWYK+ I + F ++ L++ D G+YT SN
Sbjct: 1307 FHCKMSGYPLPKIAWYKDGKRIKHGERYHMDFLQDGRASLRIPVVLPEDEGIYTAFASNM 1366
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQ-------W 1235
G+A+C+ + + EP P ++ TP VS +S PIR+
Sbjct: 1367 KGNAICSGKLYV-EPAAPLSAPTYIPTPEPVS--RIRSISPRSVSRSPIRMSPARMSPAR 1423
Query: 1236 LKAGREIKPSDR---------------CSFSFANG-TAVLEFKDV--------------- 1322
+ GR ++ +D SF G TA + K V
Sbjct: 1424 MSPGRRLEETDESQLERLYKPVFVLKPTSFKCVEGQTARFDLKVVGRPMPETFWFHDGQQ 1483
Query: 1323 ------------------------TKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
T +D+G++ A N AG + +T
Sbjct: 1484 IVNDYTHKVVVKEDGTQSLLIVPATPSDSGEWTVVAQNRAGKSSISVILTVEAVEHQV-- 1541
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQL-NQGGRIFI 1607
K FV + +++ + E + + G+P P++ W K + ++ +I I
Sbjct: 1542 --------KPVFVEKLRNLNIKEGSRLEMKVRATGNPNPDIVWLKNSEIIVPHKYPKIRI 1593
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG----EIESNVNLQVNERKKQEKI---EGD 1766
EA L+I T DS Y A NK G + NV ++ E + + ++ G
Sbjct: 1594 EGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERRLIIPRGT 1653
Query: 1767 LRAMLKKTPV-----LKKGAGEEEEIDIMELLKNVDP 1862
RA P L+ G + EE D+ + K P
Sbjct: 1654 YRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1690
Score = 104 bits (260), Expect = 3e-22
Identities = 134/565 (23%), Positives = 224/565 (39%), Gaps = 3/565 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G A L+C+++ V WY D +++P + LV N+ ++D G
Sbjct: 2441 VNVLEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVHAIVKGTKQRLVINRTHASDEG 2500
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y + VG V +S L+V++ K+ R LRD+ T VV E +S S I V
Sbjct: 2501 PY----KLVVGRVETSCDLSVEKIKI----IRGLRDLTCTETQNVVLEVELSHS-GIDVL 2551
Query: 366 W-FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W FKD + +K + + L + + G+Y+ A G +S +L +
Sbjct: 2552 WNFKD-KEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGEYTFYA----GENRTSGKLTVAG 2606
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
G PL + A FEC V + W KD + + +
Sbjct: 2607 GA----ISKPLTDQTVAESQEAVFECEVANPDS-EGEWLKDGKHLPLSKTIRSESDGRKR 2661
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I D G+YT +V +A+L ++ I + K L TV ET+ F
Sbjct: 2662 RLIIAATKLDDIGEYT----YKVATSKTSAKLKVEAVKIKKTL-KNL--TVTETQDAVFT 2714
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
+E + V W +N V + + ++ K L++K ++ D +Y K+
Sbjct: 2715 VE--LTHPNVKGVQWIRNGVVLESSDKYTVSVKGTVYSLRIKNCAVADESVYGFKLGKLG 2772
Query: 1083 GSA-LCTSSI-VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
SA L ++ +IK+PK VT E + V + + ++W EI
Sbjct: 2773 ASARLHVETVKIIKKPK----------DVTALENATVSFEVSV-SHDTVPVKWFHKNVEI 2821
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
KPSD+ L + ++ +DAG+Y V G K+K+
Sbjct: 2822 KPSDKHRLVSERKVHKLMLQHISPSDAGEYTA----VVGQLECKAKLFVE---------- 2867
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
L ++I V E TA+F +V +P++ G ++++ +I + +
Sbjct: 2868 ------TLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVV--Q 2919
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFN 1691
G +L I +T+ DS Y V N
Sbjct: 2920 GKLHQLIIMNTSTEDSAEYTFVCGN 2944
Score = 99.8 bits (247), Expect = 8e-21
Identities = 140/563 (24%), Positives = 229/563 (40%), Gaps = 5/563 (0%)
Frame = +3
Query: 24 DSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRA 203
+SAS +++ G KG+ LRP+ T ++ + L + V + +GE + +A
Sbjct: 11429 ESASFDAEISEVDVPGQWKLKGEL-LRPSPTCEIKAEDGKRFLTLHNVKLDQAGEVLYQA 11487
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGR 383
N+V ++ LTV+E +L F+ L+DV FEC ++ +V W K
Sbjct: 11488 LNAV----TTAILTVKEIEL--DFAVPLKDVTVPEKRQARFECVLT--REANVIWSKGPD 11539
Query: 384 PLK--DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
+K D +I T ++ +N Q D G Y T + +SARL +T R
Sbjct: 11540 IIKSSDKFDIITDGKKHILVINNSQFDDE--GVY----TAEVEGKKTSARLFVTGIRLK- 11592
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F PL GE+A F C ++ + + V W K++ ++ + IS + L +
Sbjct: 11593 -FISPLEDQTVKEGETATFVCELSH-EKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMR 11650
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET--VEETEGNSFRLEG 911
+V D Q +V S TA L + E P FT KL + VE+ E +
Sbjct: 11651 EVTMDDISQIKA----QVKDLSSTANLKVIEA--DPYFTVKLHDKTGVEKDE-----IVL 11699
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
R S+ + V W+K+ E+ P+ I +L++KKA + D G Y C D A
Sbjct: 11700 RCEVSKDVPVKWFKDGEELLPSPKHSIKADGLRRILKIKKADLKDKGEYVCDCGTDTTKA 11759
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEP-IRIQWLKAGREIKPSD 1268
T + + +KP L V V GE + + SEP + QW G + S
Sbjct: 11760 NVTVEARLIKVEKP------LYGVEVFVGETARFEIEL--SEPDVHGQWKLKGEPLTASP 11811
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
C +L + G +A+N + K K
Sbjct: 11812 DCEIIEDGKKHILVLYNCRLDMTGKVSFQAANAKSAANLKVK------------------ 11853
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
+ L F++ ++V EK A F +V +P +W KG +++ RI + + G +
Sbjct: 11854 ELPLIFITPLSDVKVFEKDEAKFECEVSREP-KTYRWLKGT-QEITGDDRIELIKDGTKH 11911
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKH 1697
L I+ D Y A ++H
Sbjct: 11912 SLVIKSAAFEDEAKYIFEAEDQH 11934
Score = 99.4 bits (246), Expect = 1e-20
Identities = 151/611 (24%), Positives = 242/611 (39%), Gaps = 8/611 (1%)
Frame = +3
Query: 15 TVGDS--ASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
TV +S A +C++A P+ W K L + T + L+ +D GE
Sbjct: 2617 TVAESQEAVFECEVAN-PDSEGEWLKDGKHLPLSKTIRSESDGRKRRLIIAATKLDDIGE 2675
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y + S +S L V+ K+ + L+++ T VF ++ V W
Sbjct: 2676 YTYKVATS----KTSAKLKVEAVKI----KKTLKNLTVTETQDAVFTVELTHPNVKGVQW 2727
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
++G L+ S V +L I + Y +G +SARL + +
Sbjct: 2728 IRNGVVLESSDKYTVSVKGTVYSLRIKNCAVADESVYGFK----LGKLGASARLHVETVK 2783
Query: 549 NPPFFDIPLAPVDAVVGESA--DFECHVT-GTQPIKVAWAKDNREIRSGGNYQISYLENS 719
I P D E+A FE V+ T P+K W N EI+ +++
Sbjct: 2784 ------IIKKPKDVTALENATVSFEVSVSHDTVPVK--WFHKNVEIKPSDKHRLVSERKV 2835
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET-VEETEGNS 896
L + + D G+YT VG+ C A+L ++ I TK + V ET+ S
Sbjct: 2836 HKLMLQHISPSDAGEYTAV----VGQLECKAKLFVETLHI----TKTMKNIEVPETKTAS 2887
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
F E + W KN VEI + +I + L + S D+ YT N
Sbjct: 2888 FECE---VSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 2944
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
D SA + P + L + E + + V E I +WLK G EI
Sbjct: 2945 DQVSATLKVT--------PIMITSMLKDINAEEKDTITFEVTVN-YEGISYKWLKNGVEI 2995
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
K +DRC T L ++V DA +Y + VAG TS + +
Sbjct: 2996 KSTDRCQMRTKKLTHSLNIRNVHFGDAAEY----TFVAGKATSTATL------------- 3038
Query: 1437 XXXVDGK-LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
V+ + + F + I+V+EK A F +V +P V+W K ++L RI I +
Sbjct: 3039 --YVEARHIEFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMK-DGQELQLVDRIKIQK 3094
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK-KQEKIEGDLRAMLKKT 1790
+ +L I T +D+G Y VA G S+ NL V R + I+ +++ + K+
Sbjct: 3095 EKYVHRLLIPSTRMSDAGKYTVVA----GGNMSSANLFVEGRDVRIRSIKREVQVIEKQR 3150
Query: 1791 PVLKKGAGEEE 1823
V++ E++
Sbjct: 3151 AVVEFEVNEDD 3161
Score = 98.2 bits (243), Expect = 2e-20
Identities = 81/303 (26%), Positives = 126/303 (41%), Gaps = 36/303 (11%)
Frame = +3
Query: 318 VVFECAVSG-SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTAT 494
V + C + + V+W+ R L++ + ++ D VAT+ + + G Y C
Sbjct: 31602 VKYVCRIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVATMYVKDITKFDDGTYRCKVV 31661
Query: 495 NPIGSASSSARLILTEGRN-------------------------PPFFDIPLAPVDAVVG 599
N G SS A L + R PP F +PL A VG
Sbjct: 31662 NDYGEDSSYAELFVKGVREVYDYYCRRTVKKLKRRTDAMRLLERPPEFTLPLYNKTAYVG 31721
Query: 600 ESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA---HLTILKVDKGDTGQYT 770
E+ F +T +V W K ++I+ G + + E+ LTI V D +YT
Sbjct: 31722 ENVRFGVTITVHPEPRVTWYKSGQKIKPGDDDRKYIFESDKGLYQLTINSVTMDDDAEYT 31781
Query: 771 CYAVNEVGKDSCTAQLNIKERLIPPSFT------KKLSETVEETEGNSFRLEGRVAGSQP 932
A N+ G+DSC A+L + PPS T K+L E EG S E RV+G P
Sbjct: 31782 VVARNKYGEDSCKAKLTVTPHP-PPSDTTLRPMFKRLLANAECQEGQSVCFEIRVSGIPP 31840
Query: 933 ISVAWYKNNVEIHPTANCEITFKN-NALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSI 1109
++ W K+ + N EI + + L ++ D G Y +N AGS+ C + +
Sbjct: 31841 PTLKWEKDGRPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSSSCQAHL 31900
Query: 1110 VIK 1118
++
Sbjct: 31901 QVE 31903
Score = 97.4 bits (241), Expect = 4e-20
Identities = 134/575 (23%), Positives = 217/575 (37%), Gaps = 3/575 (0%)
Frame = +3
Query: 3 PVK-VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSND 179
P+K VTV + + + T E V W KG ++ + + + LV N +D
Sbjct: 11508 PLKDVTVPEKRQARFECVLTREANVIWSKGPDIIKSSDKFDIITDGKKHILVINNSQFDD 11567
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
G Y E + S+ F+T K F L D G F C +S E +
Sbjct: 11568 EGVYTAEVEGK--KTSARLFVTGIRLK----FISPLEDQTVKEGETATFVCELS-HEKMH 11620
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V WFK+ L + S L + + Q + SS+A L +
Sbjct: 11621 VVWFKNDAKLHTSRTVLISSEGKTHKLEMREVTMDDISQIKA----QVKDLSSTANLKVI 11676
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E P+F + L V + C V+ P+K W KD E+ + I
Sbjct: 11677 EA--DPYFTVKLHDKTGVEKDEIVLRCEVSKDVPVK--WFKDGEELLPSPKHSIKADGLR 11732
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I K D D G+Y C + G D+ A + ++ RLI +K VE G +
Sbjct: 11733 RILKIKKADLKDKGEYVC----DCGTDTTKANVTVEARLIK---VEKPLYGVEVFVGETA 11785
Query: 900 RLEGRVAGSQP-ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
R E + S+P + W + + +CEI +L + + G KVS
Sbjct: 11786 RFE--IELSEPDVHGQWKLKGEPLTASPDCEIIEDGKKHILVLYNCRLDMTG----KVSF 11839
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
A +A +++ +KE P +F L+ V V E + + C V EP +WLK +EI
Sbjct: 11840 QAANAKSAANLKVKE--LPLIFITPLSDVKVFEKDEAKFECEV-SREPKTYRWLKGTQEI 11896
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
DR L K D Y+ +A + TS +
Sbjct: 11897 TGDDRIELIKDGTKHSLVIKSAAFEDEAKYIFEAED---QHTSGKLI------------- 11940
Query: 1437 XXXVDG-KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
++G +L F++ + + E+ +A F ++ D I V+W K R L+ + +
Sbjct: 11941 ---IEGIRLKFLTPLKDVTAKERESAVFTVELSHDNI-RVRWFKNDQR-LHTSKFVSMDD 11995
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNV 1718
+G + R+ + D+ + A E + V
Sbjct: 11996 EGKTHSITFRNLSIDDTSQIKVEAMGLSSEAKLTV 12030
Score = 96.7 bits (239), Expect = 7e-20
Identities = 88/308 (28%), Positives = 129/308 (41%), Gaps = 36/308 (11%)
Frame = +3
Query: 72 VSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVSSSTFL--- 242
V+WY G +L + Y++ + + VAT+ + D G Y C+ N GE SS L
Sbjct: 31617 VTWYFGVRQLENSEKYEITYEDGVATMYVKDITKFDDGTYRCKVVNDYGEDSSYAELFVK 31676
Query: 243 ------------TVQEQK----------LPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
TV++ K PP F+ L + VG V F ++
Sbjct: 31677 GVREVYDYYCRRTVKKLKRRTDAMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEP 31736
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDN---VATLNIFQTDRSFAGQYSCTATNPIGSASSSAR 527
V+W+K G+ +K G + + ++ + L I +Y+ A N G S A+
Sbjct: 31737 RVTWYKSGQKIKPGDDDRKYIFESDKGLYQLTINSVTMDDDAEYTVVARNKYGEDSCKAK 31796
Query: 528 LILTEGRNP------PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGG 689
L +T P P F LA + G+S FE V+G P + W KD R + G
Sbjct: 31797 LTVTPHPPPSDTTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGRPLSLGP 31856
Query: 690 NYQISY--LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKL 863
N +I + L+ A L I DTG Y A N G SC A L + ERL + K+
Sbjct: 31857 NIEIIHEGLDYYA-LHIRDTLPEDTGYYRVTATNTAGSSSCQAHLQV-ERL---RYVKQE 31911
Query: 864 SETVEETE 887
+T EE E
Sbjct: 31912 FKTKEEHE 31919
Score = 95.5 bits (236), Expect = 2e-19
Identities = 140/580 (24%), Positives = 225/580 (38%), Gaps = 6/580 (1%)
Frame = +3
Query: 15 TVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYI 194
+VG SA +C ++ + + SW K + +R + ++ L V +D+GEY
Sbjct: 11148 SVGSSAIFECLVSPSTAV-TSWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYT 11206
Query: 195 CRAENSVGEVSSSTFLTVQEQKLPPSFSRQL-RDVQETVGLPVVFECAVSGSEPISVSWF 371
C E +S+ L V+E LP F + L +V G P+ C ++ V W
Sbjct: 11207 CVLRLGNKEKTSTAKLIVEE--LPVRFVKTLEEEVTVVKGQPLYLSCELNKER--DVVWR 11262
Query: 372 KDGRPLKDGP-NIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
KDG+ + + P I + + L I D S AG Y+ T N SS ++ R
Sbjct: 11263 KDGKIVVEKPGKIVPGVIGLLRALTINDADDSDAGTYTVTVENANNLECSSCVKVVEVIR 11322
Query: 549 N---PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
+ P D + P V F C + P + W K EI + + +
Sbjct: 11323 DWLVKPIRDQHVKPKGTAV-----FTCVIAKDTP-NIKWYKGYDEIPWEPTDKTEIIRDG 11376
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE-TVEETEGNS 896
H+ LKV YAV GK A+L + ER + K + + T+ E E S
Sbjct: 11377 NHIH-LKVKNAMPEDIDEYAVEIEGK-RYPAKLTLGEREV--ELLKPIEDVTIYEKESAS 11432
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
F E + W + P+ CEI ++ L + + AG +V
Sbjct: 11433 FDAE---ISEVDVPGQWKLKGELLRPSPTCEIKAEDGKRFLTLHNVKLDQAG----EVLY 11485
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
A +A+ T+ + +KE + F L VTV E + C + + + W K I
Sbjct: 11486 QALNAVTTAILTVKEIELD--FAVPLKDVTVPEKRQARFECVL--TREANVIWSKGPDII 11541
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
K SD+ +L + D G Y + V G TS
Sbjct: 11542 KSSDKFDIITDGKKHILVINNSQFDDEGVY---TAEVEGKKTSARLFVTGI--------- 11589
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
+L F+S + V E TATF+ ++ + + +V W K +L+ + I +
Sbjct: 11590 ------RLKFISPLEDQTVKEGETATFVCELSHEKM-HVVWFKND-AKLHTSRTVLISSE 11641
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
G KLE+R+ T D + + ++ S NL+V E
Sbjct: 11642 GKTHKLEMREVTMDDISQIKA----QVKDLSSTANLKVIE 11677
Score = 95.1 bits (235), Expect = 2e-19
Identities = 88/324 (27%), Positives = 127/324 (39%), Gaps = 36/324 (11%)
Frame = +3
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS 1106
Q V WY ++ + EIT+++ + VK + D G Y CKV ND G +
Sbjct: 31613 QSTQVTWYFGVRQLENSEKYEITYEDGVATMYVKDITKFDDGTYRCKVVNDYGEDSSYAE 31672
Query: 1107 IVIKEPK-------------------------KPPVFDQHLTPVTVSEGEFLQLSCHVRG 1211
+ +K + +PP F L T GE ++ +
Sbjct: 31673 LFVKGVREVYDYYCRRTVKKLKRRTDAMRLLERPPEFTLPLYNKTAYVGENVRFGVTITV 31732
Query: 1212 SEPIRIQWLKAGREIKPSD---RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
R+ W K+G++IKP D + F G L VT D +Y A N G D+
Sbjct: 31733 HPEPRVTWYKSGQKIKPGDDDRKYIFESDKGLYQLTINSVTMDDDAEYTVVARNKYGEDS 31792
Query: 1383 SKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWT 1562
K+K+T +L +E Q E + F +V G P P +KW
Sbjct: 31793 CKAKLTVTPHPPPSDTTLRPMFK-RLLANAECQ-----EGQSVCFEIRVSGIPPPTLKWE 31846
Query: 1563 KGKWRQLNQGGRI-FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV--- 1730
K R L+ G I IH+ D L IRDT D+G YR A N G +LQV
Sbjct: 31847 KDG-RPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSSSCQAHLQVERL 31905
Query: 1731 ----NERKKQEKIEGDLRAMLKKT 1790
E K +E+ E ++ + KT
Sbjct: 31906 RYVKQEFKTKEEHERHVQRQIDKT 31929
Score = 89.7 bits (221), Expect = 8e-18
Identities = 115/484 (23%), Positives = 185/484 (38%), Gaps = 7/484 (1%)
Frame = +3
Query: 243 TVQEQKLPPSFSRQLRDV----QETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQ 410
T Q + +P F ++++D+ E+VG +FEC VS S ++ SW KDG +++ P +
Sbjct: 11124 TYQLKAVPLKFVKEIKDIVLTEAESVGSSAIFECLVSPSTAVT-SWMKDGSNIRESPKHR 11182
Query: 411 TSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDA 590
L+I S AG+Y+C +S+A+LI+ E F V
Sbjct: 11183 FIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEE-LPVRFVKTLEEEVTV 11241
Query: 591 VVGESADFECHVTGTQPIKVAWAKDNR-EIRSGGNYQISYLENSAHLTILKVDKGDTGQY 767
V G+ C + + V W KD + + G + LTI D D G Y
Sbjct: 11242 VKGQPLYLSCELNKER--DVVWRKDGKIVVEKPGKIVPGVIGLLRALTINDADDSDAGTY 11299
Query: 768 TCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAW 947
T V C++ + + E +I K + + + +G + + V ++ W
Sbjct: 11300 T-VTVENANNLECSSCVKVVE-VIRDWLVKPIRDQHVKPKGTA--VFTCVIAKDTPNIKW 11355
Query: 948 YKNNVEI--HPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKE 1121
YK EI PT EI N + L+VK A D Y ++ A T E
Sbjct: 11356 YKGYDEIPWEPTDKTEIIRDGNHIHLKVKNAMPEDIDEYAVEIEGKRYPAKLTLGEREVE 11415
Query: 1122 PKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTA 1301
KP + VT+ E E + + QW G ++PS C +G
Sbjct: 11416 LLKP------IEDVTIYEKESASFDAEI-SEVDVPGQWKLKGELLRPSPTCEIKAEDGKR 11468
Query: 1302 VLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQ 1481
L +V AG+ + +A N + K + +L F +
Sbjct: 11469 FLTLHNVKLDQAGEVLYQALNAVTTAILTVK------------------EIELDFAVPLK 11510
Query: 1482 SIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTD 1661
+ V EK A F + + NV W+KG + + I G + L I ++ D
Sbjct: 11511 DVTVPEKRQARFECVLTRE--ANVIWSKGP-DIIKSSDKFDIITDGKKHILVINNSQFDD 11567
Query: 1662 SGLY 1673
G+Y
Sbjct: 11568 EGVY 11571
Score = 88.6 bits (218), Expect = 2e-17
Identities = 66/182 (36%), Positives = 82/182 (45%), Gaps = 11/182 (6%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRP---TATYKMHFRNNVATLVFNQVDSNDSGE 188
VG++ + PE V+WYK K++P Y + L N V +D E
Sbjct: 31720 VGENVRFGVTITVHPEPRVTWYKSGQKIKPGDDDRKYIFESDKGLYQLTINSVTMDDDAE 31779
Query: 189 YICRAENSVGEVSSSTFLTV------QEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
Y A N GE S LTV + L P F R L + + G V FE VSG
Sbjct: 31780 YTVVARNKYGEDSCKAKLTVTPHPPPSDTTLRPMFKRLLANAECQEGQSVCFEIRVSGIP 31839
Query: 351 PISVSWFKDGRPLKDGPNIQT--SFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
P ++ W KDGRPL GPNI+ LD A L+I T G Y TATN GS+S A
Sbjct: 31840 PPTLKWEKDGRPLSLGPNIEIIHEGLDYYA-LHIRDTLPEDTGYYRVTATNTAGSSSCQA 31898
Query: 525 RL 530
L
Sbjct: 31899 HL 31900
Score = 88.6 bits (218), Expect = 2e-17
Identities = 89/385 (23%), Positives = 148/385 (38%), Gaps = 14/385 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ +T G +L+ +AG + V W +L + Y+ + TL Q D G
Sbjct: 33076 MSITAGQKVTLKANIAGATD--VKWVLNGVELSNSDEYRYGISGSDQTLTIRQAGHKDEG 33133
Query: 186 EYICRAENSVGEVSSSTFLTV-QEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
C + S G + LT+ +E P+F Q R G V+F C +SG +
Sbjct: 33134 ILTCIGKTSQGIIKCQYDLTLSKELSDAPAFISQPRSQNVNEGQNVLFSCEISGEPSPEI 33193
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WFK+ P+ NI S NV +L I S +G+Y+ A N G S++A L +
Sbjct: 33194 EWFKNNLPISISSNISVSRSRNVYSLEIRNASVSDSGKYTIKAKNFHGQCSATASLTVL- 33252
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVT-GTQPIKVAWAKDNREIRSGGNYQISYLENS 719
P + P P + V+ S D + +Q ++++ +K S + S +
Sbjct: 33253 ----PLVEEP--PREVVLRTSGDTSLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEM 33306
Query: 720 --AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERL-------IPPSFTKKLSET 872
A ++ + + + +GK S T + R+ IPP + L
Sbjct: 33307 KFASMSAQSMSSMQESFVEMSSSSFMGKSSMTQLESSTSRMLKAGLRGIPPKI-EALPSD 33365
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIH---PTANCEITFKNNALLLQVKKASMG 1043
+ EG + G + W + IH I ++ L +
Sbjct: 33366 ISIDEGKVLTVACAFTGEPTPEITWSRGGRTIHDQEQRGRFHIENTDDLTTLIIMDVRKQ 33425
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIK 1118
D GLYT + N+ GS T +I I+
Sbjct: 33426 DGGLYTLSLGNEFGSDSATVNINIR 33450
Score = 88.2 bits (217), Expect = 2e-17
Identities = 99/440 (22%), Positives = 165/440 (37%), Gaps = 62/440 (14%)
Frame = +3
Query: 264 PPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLN 443
PP+ L++V G V EC +SG V+W+++ ++ + Q +F +A L
Sbjct: 939 PPTLVSGLKNVTVIEGESVTLECHISGYPSPKVTWYREDYQIESSIDFQITFQSGIARLL 998
Query: 444 IFQTDRSFAGQYSCTATNPIGSASSS------------------ARLILTEGRN------ 551
I + +G+++CTA N G+ S+S A I TE +
Sbjct: 999 IREAFAEDSGRFTCTAVNEAGTVSTSCYLAVQVSEEFEKETTAVAEKITTEEKRFVESRD 1058
Query: 552 -------------------PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE 674
PFF V G S FEC V G V W K
Sbjct: 1059 VVMTDTSITEEHAGPGEPAAPFFITKPVVQKLVEGGSIVFECQVGGNPKPHVYWKKSGVP 1118
Query: 675 IRSGGNYQISYLENS--AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPS 848
+ SG Y++SY + + L I D G+YT N+ G+ S +A L E S
Sbjct: 1119 LTSGYRYKVSYNKQTGECRLVISMTFADDAGEYTIVIRNKHGETSASASL--LEEADYES 1176
Query: 849 FTKKLSETVEETEGNSFRLEGRVAGSQPISV-AWYKNNVEIHPTANCEITFKNNALLLQV 1025
K E + +T+ +F E +V P V + Y+ E + K+ ++
Sbjct: 1177 LMKSQQEMLYQTQVTAFVQEPKVGEIAPGYVYSEYEKEYEKEQALIRKKMAKDTVMVRTF 1236
Query: 1026 KKASMGDAGLYTCKVSNDAGSALCTSSI--VIKEPKKPPV-------------FDQHLTP 1160
+ + ++ + + +++ +++E + + FD +
Sbjct: 1237 VEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAIEAGFDLRVKN 1296
Query: 1161 VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSF-ANGTAVLEFKDVTKADA 1337
+ EG + C + G +I W K G+ IK +R F +G A L V D
Sbjct: 1297 YRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYHMDFLQDGRASLRIPVVLPEDE 1356
Query: 1338 GDYVCKASNVAGSDTSKSKV 1397
G Y ASN+ G+ K+
Sbjct: 1357 GIYTAFASNMKGNAICSGKL 1376
Score = 79.7 bits (195), Expect = 9e-15
Identities = 87/380 (22%), Positives = 147/380 (38%), Gaps = 19/380 (5%)
Frame = +3
Query: 303 TVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYS 482
T G V + ++G+ V W +G L + + + TL I Q G +
Sbjct: 33079 TAGQKVTLKANIAGAT--DVKWVLNGVELSNSDEYRYGISGSDQTLTIRQAGHKDEGILT 33136
Query: 483 CTATNPIGSASSSARLILTEGRN--PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAW 656
C G L L++ + P F P + + G++ F C ++G ++ W
Sbjct: 33137 CIGKTSQGIIKCQYDLTLSKELSDAPAFISQPRSQ-NVNEGQNVLFSCEISGEPSPEIEW 33195
Query: 657 AKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERL 836
K+N I N +S N L I D+G+YT A N G+ S TA L + +
Sbjct: 33196 FKNNLPISISSNISVSRSRNVYSLEIRNASVSDSGKYTIKAKNFHGQCSATASLTVLPLV 33255
Query: 837 IPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALL 1016
P E V T G++ L+G + SQ + ++ K ++ + + +
Sbjct: 33256 EEPP-----REVVLRTSGDT-SLQGSFS-SQSVQMSASKQEASFSSFSS-----SSASSM 33303
Query: 1017 LQVKKASMGDAGLYTCK---VSNDAGSALCTSSIVIKEPKK-----------PPVFDQHL 1154
++K ASM + + + V + S + SS+ E PP +
Sbjct: 33304 TEMKFASMSAQSMSSMQESFVEMSSSSFMGKSSMTQLESSTSRMLKAGLRGIPPKIEALP 33363
Query: 1155 TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD---RCSFSFANGTAVLEFKDVT 1325
+ +++ EG+ L ++C G I W + GR I + R + L DV
Sbjct: 33364 SDISIDEGKVLTVACAFTGEPTPEITWSRGGRTIHDQEQRGRFHIENTDDLTTLIIMDVR 33423
Query: 1326 KADAGDYVCKASNVAGSDTS 1385
K D G Y N GSD++
Sbjct: 33424 KQDGGLYTLSLGNEFGSDSA 33443
Score = 79.3 bits (194), Expect = 1e-14
Identities = 52/180 (28%), Positives = 93/180 (51%), Gaps = 3/180 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATY---KMHFRNNVATLVFNQVDSN 176
V V G +A+ + ++G P VSW++ D ++ T+T ++ F + A L V
Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSWFR-DGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
+SG Y RA N G+ +S+ L V + PP+F+++L+ + G V + V+G
Sbjct: 74 NSGRYSLRATNGSGQATSTAELLVTAETAPPNFTQRLQSMTVRQGSQVRLQVRVTGIPTP 133
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
V +++DG ++ + Q S + +L I + +G YS ATN +G A+S+A L++
Sbjct: 134 VVKFYRDGAEIQSSLDFQISQEGELYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 79.3 bits (194), Expect = 1e-14
Identities = 73/288 (25%), Positives = 117/288 (40%), Gaps = 33/288 (11%)
Frame = +3
Query: 1113 IKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFAN 1292
++ P PP L VTV EGE + L CH+ G ++ W + +I+ S +F +
Sbjct: 933 VEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPKVTWYREDYQIESSIDFQITFQS 992
Query: 1293 GTAVLEFKDVTKADAGDYVCKASNVAGS------------------DTSKSKVTXXXXXX 1418
G A L ++ D+G + C A N AG+ T+ ++
Sbjct: 993 GIARLLIREAFAEDSGRFTCTAVNEAGTVSTSCYLAVQVSEEFEKETTAVAEKITTEEKR 1052
Query: 1419 XXXXXXXXXVDGKL-------------FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW 1559
D + FF+++P ++VE + F +VGG+P P+V W
Sbjct: 1053 FVESRDVVMTDTSITEEHAGPGEPAAPFFITKPVVQKLVEGGSIVFECQVGGNPKPHVYW 1112
Query: 1560 TKGKWRQLNQGGR--IFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
K L G R + +++ E +L I T D+G Y V NKHGE ++ +L
Sbjct: 1113 KK-SGVPLTSGYRYKVSYNKQTGECRLVISMTFADDAGEYTIVIRNKHGETSASASLL-- 1169
Query: 1734 ERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEIDIMELLKNVDPKEYEK 1877
E E + + ML +T V +E + E+ EYEK
Sbjct: 1170 EEADYESLMKSQQEMLYQTQV----TAFVQEPKVGEIAPGYVYSEYEK 1213
Score = 79.0 bits (193), Expect = 1e-14
Identities = 97/457 (21%), Positives = 175/457 (38%)
Frame = +3
Query: 30 ASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAEN 209
A+ +C+ + P + V WYK ++ Y+MH V L +D++D+ +Y C
Sbjct: 2179 ATFECETS-EPFVKVKWYKDGVEIHTGDKYRMHSDRKVHFLSVLMIDTSDAEDYSCVL-- 2235
Query: 210 SVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPL 389
V + + T + + F ++L+D++ EC ++ E I W+ G L
Sbjct: 2236 -VEDENVKTTAKLIVEGAVVEFVKELQDIEVPESFSGELECIIT-PENIEGKWYHKGVEL 2293
Query: 390 KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDI 569
K + L + + G+YS + ++ +L + P
Sbjct: 2294 KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFV----VDGKKTTCKLKMKP--RPIAILQ 2347
Query: 570 PLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDK 749
L+ G+ E V+ + ++ W KD E++ G I + S L I + K
Sbjct: 2348 GLSDQKVCEGDIVQLEVKVS-LENVEGVWMKDGEEVQPGDRVHIVIDKQSHMLLIEDMTK 2406
Query: 750 GDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQ 929
D G Y+ + + +G + +I P + V EG LE +V+
Sbjct: 2407 EDAGHYS-FTIPSLGLSTHGRVSVYSVDVITP------LKDVNVLEGTKAVLECKVSVPD 2459
Query: 930 PISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSI 1109
SV WY N+ +I P K L + + D G Y V G + +
Sbjct: 2460 VTSVKWYLNDEQIKPDDRVHAIVKGTKQRLVINRTHASDEGPYKLVV----GRVETSCDL 2515
Query: 1110 VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFA 1289
+++ K + L +T +E + + L + S I + W +EIKPS +
Sbjct: 2516 SVEKIK----IIRGLRDLTCTETQNVVLEVELSHS-GIDVLWNFKDKEIKPSSKYKIEAH 2570
Query: 1290 NGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
L ++ K D G+Y + AG + + K+T
Sbjct: 2571 GKIYKLTVLNMMKDDEGEY----TFYAGENRTSGKLT 2603
Score = 78.2 bits (191), Expect = 3e-14
Identities = 126/563 (22%), Positives = 206/563 (36%), Gaps = 48/563 (8%)
Frame = +3
Query: 186 EYICRAENSVG-------EVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSG 344
E+ AEN G +S T LT E P ++++DV +G C + G
Sbjct: 30519 EFRVFAENETGLSRPRRTAMSVKTKLTSGEA---PGVRKEMKDVTTKLGEAAQLSCQIVG 30575
Query: 345 SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
+ WF+ G+ L + S TL + ++ G Y+C ATN +G SS+
Sbjct: 30576 RPLPDIKWFRFGKELVQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCVATNEVGEVESSS 30635
Query: 525 RLILTEGRNPPFFDIPLAPVD----AVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
+L+L P F P P+ VG + G + W + + +++ N
Sbjct: 30636 KLLLQ--ATPQFH--PGYPLKEKYYGAVGSTLRIHVMYIGRPVPAITWFRGQKLLQNSEN 30691
Query: 693 YQISYLENSAHLTILKVD-KGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE 869
I E+ HL + V K G+Y N +G + I+++ P+ +
Sbjct: 30692 ITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVLGTVDTMLDVEIQDKPDKPTGPIVIEA 30751
Query: 870 TVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDA 1049
++ + S++ GS W N V CE K A V A
Sbjct: 30752 LLKNSVVISWKPPADDGGS------WITNYV----VEKCEA--KEGAEWQLVSSA----I 30795
Query: 1050 GLYTCKVSNDAGSA------------------LCTSSIVIKEPKKPPVFDQHLTPVTVSE 1175
+ TC++ N +A +S ++IK P + P T V++
Sbjct: 30796 SVTTCRIVNLTENAGYYFRVSAQNMFGISEPLEVSSVVIIKSPFEKPGAPGKPTITAVTK 30855
Query: 1176 GEFLQLSCHVR-------GSEPIRIQWLKAGREIKPSD----------RCSFSFANGTAV 1304
SC V G IR +L+ RE K + FS N
Sbjct: 30856 D-----SCVVAWKPPASDGGAKIRNYYLEK-REKKQNKWIAVTTDEIRETVFSVQNLIEG 30909
Query: 1305 LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS 1484
LE++ K + + S ++ T KS V F E ++
Sbjct: 30910 LEYEFRVKCENLGGESEWSEISEPVTPKSDVPIQAP----------------HFKEELRN 30953
Query: 1485 IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ-KGDEAKLEIRDTTKTD 1661
+ V ++ AT + KV G P P VKW + + G + I + KG +L I T D
Sbjct: 30954 LNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDD 31013
Query: 1662 SGLYRCVAFNKHGEIESNVNLQV 1730
+ +Y+ A N+ G + +L+V
Sbjct: 31014 ATVYQVRATNQGGSVSGTASLEV 31036
Score = 76.3 bits (186), Expect = 1e-13
Identities = 69/287 (24%), Positives = 110/287 (38%), Gaps = 35/287 (12%)
Frame = +3
Query: 636 QPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQ 815
Q +V W R++ + Y+I+Y + A + + + K D G Y C VN+ G+DS A+
Sbjct: 31613 QSTQVTWYFGVRQLENSEKYEITYEDGVATMYVKDITKFDDGTYRCKVVNDYGEDSSYAE 31672
Query: 816 LNIK-----------------------ERLI--PPSFTKKLSETVEETEGNSFRLEGRVA 920
L +K RL+ PP FT L G + R +
Sbjct: 31673 LFVKGVREVYDYYCRRTVKKLKRRTDAMRLLERPPEFTLPLYNKTAYV-GENVRFGVTIT 31731
Query: 921 GSQPISVAWYKNNVEIHP-TANCEITFKNNALLLQ--VKKASMGDAGLYTCKVSNDAGSA 1091
V WYK+ +I P + + F+++ L Q + +M D YT N G
Sbjct: 31732 VHPEPRVTWYKSGQKIKPGDDDRKYIFESDKGLYQLTINSVTMDDDAEYTVVARNKYGED 31791
Query: 1092 LCTSSIVIKEPKKP------PVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
C + + + P P+F + L EG+ + V G P ++W K GR
Sbjct: 31792 SCKAKLTVTPHPPPSDTTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGRP 31851
Query: 1254 IKPSDRCSFSFAN-GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS 1391
+ L +D D G Y A+N AGS + ++
Sbjct: 31852 LSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSSSCQA 31898
Score = 74.7 bits (182), Expect = 3e-13
Identities = 154/769 (20%), Positives = 254/769 (33%), Gaps = 158/769 (20%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHF-RNNVATLVFNQVDSNDSG 185
++ G + C+++G P ++WYK +++ Y M F ++ A+L V D G
Sbjct: 1298 RILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYHMDFLQDGRASLRIPVVLPEDEG 1357
Query: 186 EYICRAENSVGE--------------VSSSTFLTVQEQ---------------------- 257
Y A N G +S+ T++ E
Sbjct: 1358 IYTAFASNMKGNAICSGKLYVEPAAPLSAPTYIPTPEPVSRIRSISPRSVSRSPIRMSPA 1417
Query: 258 KLPPSFSRQLRDVQET-------------VGLPVVFECA----------VSGSEPISVSW 368
++ P+ R ++ET V P F+C V G W
Sbjct: 1418 RMSPARMSPGRRLEETDESQLERLYKPVFVLKPTSFKCVEGQTARFDLKVVGRPMPETFW 1477
Query: 369 FKDGRPL-KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL--T 539
F DG+ + D + D +L I S +G+++ A N G +S S L +
Sbjct: 1478 FHDGQQIVNDYTHKVVVKEDGTQSLLIVPATPSDSGEWTVVAQNRAGKSSISVILTVEAV 1537
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E + P F L ++ G + + TG + W K N EI Y +E +
Sbjct: 1538 EHQVKPVFVEKLRNLNIKEGSRLEMKVRATGNPNPDIVWLK-NSEIIVPHKYPKIRIEGT 1596
Query: 720 AHLTILKVDKG---DTGQYTCYAVNEVGKDSCTAQLNI---------------------- 824
LK+D D+ YT A+N+ G+D+ ++N+
Sbjct: 1597 KGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERRLIIPRGTYRA 1656
Query: 825 ---------------------------KERLIPPSFTKKLSETVEETEGNS-FRLEGRVA 920
KE+ P F KKL+ + G + F
Sbjct: 1657 KEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPI 1716
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G + V W + + + + L A D+G+ TC+ +N G+ +
Sbjct: 1717 GDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYAVAYSRDSGVITCRATNKYGTDHTS 1776
Query: 1101 SSIVIKEPK----------------------------------------KPPVFDQHLTP 1160
+++++K+ K + P P
Sbjct: 1777 ATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLFPEP 1836
Query: 1161 VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAG 1340
V V EGE + C V G ++ W G+ I+ S R + +G L+ D D G
Sbjct: 1837 VRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY-DGIHYLDIVDCKSYDTG 1895
Query: 1341 DYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFI 1520
+ A N G K K+ F V EP ++ F
Sbjct: 1896 EVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPKPEFHVHEPGKLQ--------FE 1947
Query: 1521 AKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTK--TDSGLYRCVAFNK 1694
+ P+ + TK R L + RI H+K E E+R K T+ G Y
Sbjct: 1948 VQKVDRPVDTTE-TKEIVR-LKRAERI-THEKVSEESEELRSKFKRRTEEGYY------- 1997
Query: 1695 HGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEIDIME 1841
E+ +++ RKK E E LR ++ K EEE+ + E
Sbjct: 1998 ----EAITAVELKSRKKDESYEELLRKTKEELLHWTKELTEEEKKALAE 2042
Score = 72.8 bits (177), Expect = 1e-12
Identities = 131/561 (23%), Positives = 215/561 (38%), Gaps = 1/561 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+V VG++A + +L+ P++ W L + ++ LV + +G
Sbjct: 11777 VEVFVGETARFEIELS-EPDVHGQWKLKGEPLTASPDCEIIEDGKKHILVLYNCRLDMTG 11835
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+ +A N+ S+ L V+E LP F L DV+ FEC VS EP +
Sbjct: 11836 KVSFQAANA----KSAANLKVKE--LPLIFITPLSDVKVFEKDEAKFECEVS-REPKTYR 11888
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W K + + I+ +L I +Y A + +S +LI+ EG
Sbjct: 11889 WLKGTQEITGDDRIELIKDGTKHSLVIKSAAFEDEAKYIFEAEDQ----HTSGKLII-EG 11943
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
F PL V A ESA F ++ I+V W K+++ + + + +
Sbjct: 11944 IRLKFLT-PLKDVTAKERESAVFTVELSHDN-IRVRWFKNDQRLHTSKFVSMDDEGKTHS 12001
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE-TVEETEGNSFR 902
+T + DT Q A+ S A+L + E P FT KL + T E E +
Sbjct: 12002 ITFRNLSIDDTSQIKVEAMGL----SSEAKLTVLEG--DPYFTGKLQDYTGVEKEEVILQ 12055
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
E A + V W+K+ EI P+ N I +L +KK D G YTC D
Sbjct: 12056 CEISKADAP---VKWFKDGQEIKPSKNAVIKADGKKRMLILKKPLKSDIGQYTC----DC 12108
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G+ + + I++ + V + L V V E E + + + I W G +
Sbjct: 12109 GTDKTSGKLNIEDREIKLV--RPLYSVEVMETETARFETEI-SEDDIHANWKLKGEALLQ 12165
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ C T L + G +A+NV S + K
Sbjct: 12166 TPECEIKEEGKTHFLILHNCRLDQTGGVDFQAANVKSSAHLRVKPRV------------- 12212
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+ + + I V TATF ++ + IP + +GK +L ++ + +G
Sbjct: 12213 -----IGLLRPLKDITVTAGETATFDCELSYEDIPVEWYLRGK--KLEPSDKVVMRSEGR 12265
Query: 1623 EAKLEIRDTTKTDSGLYRCVA 1685
L +RD D+G + VA
Sbjct: 12266 VHTLTLRDVKLEDAGEVQLVA 12286
Score = 72.0 bits (175), Expect = 2e-12
Identities = 92/413 (22%), Positives = 156/413 (37%), Gaps = 32/413 (7%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ V G + ++G P V+W + L AT + ++ ++V + G
Sbjct: 16551 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERALPQEATIETTAISS--SMVIKNCQRSHQG 16608
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y A+N+ GE + + V DV VG+P + + S ++
Sbjct: 16609 VYSLLAKNAAGERKKTIIVDVL-------------DVPGPVGIPFLAHNLTNDS--CKLT 16653
Query: 366 WFKD----GRPLKD-------------GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTAT 494
WF G P+ + P T N + Q F + A
Sbjct: 16654 WFSPEDDGGSPITNYVIEKREADHRAWTPVTYTVTRHNATVQGLIQGKAYF---FRIAAE 16710
Query: 495 NPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIK------VAW 656
N IG R+P +P P D V E +T P + +
Sbjct: 16711 NSIGMGPFVETTDALVIRDP--ITVPERPEDLEVKEVTKESVTLTWNPPKYDGGSDIINY 16768
Query: 657 AKDNREIRSGGNYQISYLEN--SAHLTILKVDKGDTGQYTCYAVNEVGKDS---CTAQLN 821
++R I + ++++ +N S T+ + +GDT +Y AVN VG+ CT +
Sbjct: 16769 VLESRLIGTEKFHKVTS-DNLMSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPIT 16827
Query: 822 IKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFK 1001
K+ L PP+ + + G +F L GR +G V+W+K+ ++ I
Sbjct: 16828 CKDELAPPTLDLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTT 16887
Query: 1002 NNALLLQVKKASMGDAGLYTCKVSNDAGS--ALCTSSIVIK--EPKKPPVFDQ 1148
L L+ KA D+G Y+ V N GS +C ++V + P P +FD+
Sbjct: 16888 PTTLALEKLKAKRSDSGKYSVVVENSTGSRKGVCQVNVVDRPGPPVGPVIFDE 16940
Score = 69.3 bits (168), Expect = 1e-11
Identities = 108/437 (24%), Positives = 161/437 (36%), Gaps = 26/437 (5%)
Frame = +3
Query: 165 VDSNDSGEYICRAENSVG---------EVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLP 317
+D N E+ A+N VG + L E L S R+L V+ G P
Sbjct: 18584 LDENQEYEFRVCAQNQVGIGRPAELKDAIKPKEILEPPEIDLDASM-RKLVTVR--AGCP 18640
Query: 318 VVFECAVSGSEPISVSWFKDG--RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTA 491
+ V G V+W K G ++ G Q +D +A L I + R +G+YS T
Sbjct: 18641 IRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDLVDTMAFLVIPNSTRDDSGKYSLTL 18697
Query: 492 TNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVT--------GTQPIK 647
NP G + N D P D V + CH++ G+Q
Sbjct: 18698 VNPAGEKAVFV--------NVRVLDTPGPVSDLKVSDVTKTSCHISWAPPENDGGSQVTH 18749
Query: 648 VAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCT---AQL 818
K E ++ + S H+T L G + AVNE G T +
Sbjct: 18750 YIVEKREAERKTWATVTPEVKKTSFHVTNLV--PGTEYFFRVTAVNEYGPGVPTDVPKPV 18807
Query: 819 NIKERLIPPSFTKKLSETVEETEGNSFR--LEGRVAGSQPISVAWYKNNVEIHPTANCEI 992
+ L P +KL E E T+ ++ L G I E P
Sbjct: 18808 LATDPLSEPDPPRKL-EVTEMTKNSAVLAWLPPLRDGGAKIDGYIVSYREEEQPADRWTE 18866
Query: 993 TFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP--VT 1166
L L V G + N G +L + + E K+ + + L P +T
Sbjct: 18867 YSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQIT 18926
Query: 1167 VSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDY 1346
+ G+ L++ HV G +W K ++ S + A ++VL KDVT+ D+G Y
Sbjct: 18927 IKAGKKLRIEAHVYGKPNPVCKWKKGEDDVVTSSHLAVHKAENSSVLIIKDVTRKDSGYY 18986
Query: 1347 VCKASNVAGSDTSKSKV 1397
A N +G+DT K KV
Sbjct: 18987 SLTAENSSGTDTQKIKV 19003
Score = 67.4 bits (163), Expect = 4e-11
Identities = 111/498 (22%), Positives = 185/498 (37%), Gaps = 43/498 (8%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V VG ++ ++G P+ ++W K D L+ T + ++ L + +D G Y
Sbjct: 23258 VQVGQDLKIEVPISGRPKPTITWTKDDLPLKQTTRINVTDSLDLTVLSIKETHKDDGGHY 23317
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
N VG+ ++S + ++ PP PV F+ +E I++SW
Sbjct: 23318 GITVANVVGQKTASIEIITLDKPDPPKG-------------PVKFDEV--SAESITLSWE 23362
Query: 372 KDGRPLKDGPNIQTSFL--DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
PL G T+++ T +++ + + + T + + + I E
Sbjct: 23363 P---PLYTGGCQITNYVVQKRDTTTTVWEVVSATVARTTLKVTK-LKTGTEYQFRIFAEN 23418
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDN------REIRSGGNYQISY 707
R F + P+ V + E GT P A +KD+ I +GG+ I Y
Sbjct: 23419 RYGQSFALESEPI---VAQYPYKEPGPPGT-PFVTAVSKDSMVVQWHEPINNGGSPVIGY 23474
Query: 708 -LENSAHLTIL-----------------KVDKGDTGQYTCYAVNEVG------------- 794
LE +IL +++G ++ YA N VG
Sbjct: 23475 HLEKKERNSILWTKVNKTIIHDTQFKAVNLEEGIEYEFRVYAENIVGIGKASKNSECYVA 23534
Query: 795 KDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS----FRLEGRVAGSQPISVAWYKNNV 962
+D C E +I L T +G S + +E R A + N +
Sbjct: 23535 RDPCDPP-GTPEAIIVKRHEITLQWTKPAYDGGSVITGYIVEKRDLPEGRWMKASFTNVI 23593
Query: 963 EIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVF 1142
E T + + + K A AG + K S+ G + + P F
Sbjct: 23594 ETQFTVSGLTEDQRYEFRVIAKNA----AGAVS-KPSDSTGPITARDEVELPRISMDPKF 23648
Query: 1143 DQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDV 1322
+ V+ GE +L V G I+WL+ +EI+ S R + A+L KD
Sbjct: 23649 RD---TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARYEIKNTDFKALLIVKDA 23705
Query: 1323 TKADAGDYVCKASNVAGS 1376
+ D G Y+ +ASNVAGS
Sbjct: 23706 IRIDGGQYILRASNVAGS 23723
Score = 67.0 bits (162), Expect = 6e-11
Identities = 50/195 (25%), Positives = 87/195 (44%), Gaps = 2/195 (1%)
Frame = +3
QLYRCVAFNKHGE 1703
L I + D G Y CVA + GE
Sbjct: 505 -GTLYIASVQEMDLGFYSCVAKSSMGE 530
Score = 98.2 bits (243), Expect = 3e-20
Identities = 79/272 (29%), Positives = 124/272 (45%), Gaps = 9/272 (3%)
Frame = +3
Query: 42 CQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGE 221
C++ G P + W K D +L PT Y++ ++ L +V + D G Y C AENSVG
Sbjct: 279 CEVQGDPPPRLRWRKEDGEL-PTGRYEIRSDHS---LWIGRVTAADEGTYTCVAENSVGR 334
Query: 222 VSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGP 401
+S L+V +PP Q +D G V F+C G+ P ++ W K+G + P
Sbjct: 335 AEASGSLSVH---VPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFP 391
Query: 402 N--IQTSFLDNVA---TLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN----P 554
+ +Q +V+ LNI AG Y C A + GS + A L + + P
Sbjct: 392 SQPLQPKGRFSVSPRGQLNITDVQSGDAGYYVCQAVSVAGSVLAKALLEVKRASSLDGLP 451
Query: 555 PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTI 734
P A +G C VTG V W KD + ++ G + Q++ + N L I
Sbjct: 452 PIILQGPANQTLALGSPVWLPCRVTGNPQPSVRWKKDGQWLQ-GDDLQLNLMANGT-LYI 509
Query: 735 LKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKE 830
V + D G Y+C A + +G+ + ++ L +E
Sbjct: 510 ASVQEMDLGFYSCVAKSSMGEATWSSWLRRRE 541
Score = 79.3 bits (194), Expect = 1e-14
Identities = 113/479 (23%), Positives = 178/479 (37%), Gaps = 30/479 (6%)
Frame = +3
Query: 417 FLDNVATLNIFQTDRSFAGQYSCTATN----PIGSASSSARLILTEGRNPPFFDIPLAPV 584
F D++A +D F S A N P G S +A + E P + P
Sbjct: 15 FADSLAGDISNSSDLLFGFNSSVAALNHSLLPPGDPSFNASRVEPEDAMPRIVE---QPP 71
Query: 585 DAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISY--LENSAHLTILKVDKG 752
D +V GE A C G + W K+ + + ++ L S L ++ G
Sbjct: 72 DLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGALFFPRIVHG 131
Query: 753 -----DTGQYTCYAVNEVGKD-SCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGR 914
D G YTC A N +G S A L + L + ++ GN G
Sbjct: 132 RRARPDEGVYTCVARNYLGAAASRNASLEVAV----------LRDDFRQSPGNVVVAVGE 181
Query: 915 VA--------GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
A G SV+W K++ + IT + L++ S DAG+Y C
Sbjct: 182 PAVMECVPPRGHPEPSVSWKKDSARLREEEG-RITIRGGKLMMSHTLKS--DAGMYVCVA 238
Query: 1071 SNDAGSALC-TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
SN AG + +V+ E +P + + V +++ + C V+G P R++W K
Sbjct: 239 SNMAGERESGAAELVVLE--RPSFLRRPVNQVVLADAP-VDFPCEVQGDPPPRLRWRKED 295
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
E+ P+ R + L VT AD G Y C A N G + ++
Sbjct: 296 GEL-PTGRYEIRSDHS---LWIGRVTAADEGTYTCVAENSVGRAEASGSLSVHVPPQ--- 348
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG-------KWRQLN 1586
V++PQ + F + G+P P + W K + L
Sbjct: 349 ------------LVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQPLQ 396
Query: 1587 QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEG 1763
GR + +G +L I D D+G Y C A + G + + L+V K+ ++G
Sbjct: 397 PKGRFSVSPRG---QLNITDVQSGDAGYYVCQAVSVAGSVLAKALLEV---KRASSLDG 449
>ref|XP_546506.2| PREDICTED: similar to Down syndrome cell adhesion molecule like 1
[Canis familiaris].
Length = 2048
Score = 144 bits (364), Expect = 2e-34
Identities = 143/577 (24%), Positives = 223/577 (38%), Gaps = 13/577 (2%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+V G + L C +G P + W K L + + + L + + + DSG
Sbjct: 231 EVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWT----KRITGLTVSDLRTEDSGT 286
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
YIC N+ G ++ LTV + P + + ++ +G V+ CA+ GS ++ W
Sbjct: 287 YICEVINTFGSAEATGTLTVID---PLHVTLTPKKLKTGIGSTVILSCALLGSPEFTIRW 343
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNuery: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V +G++A L CQ+ G P + W++ +L + YKM TL + D G
Sbjct: 30559 VTTKLGEAAQLSCQIVGRPLPDIKWFRFGKELVQSRKYKMSSDGRTHTLTVMTEEQEDEG 30618
Query: 186 EYICRAENSVGEVSSSTFLTVQ-EQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
Y C A N VGEV SS+ L +Q + P + + VG + G ++
Sbjct: 30619 VYTCVATNEVGEVESSSKLLLQATPQFHPGYPLK-EKYYGAVGSTLRIHVMYIGRPVPAI 30677
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDR-SFAGQYSCTATNPIGSASSSARLILT 539
+WF+ + L++ NI ++ L + R + AG+Y +N +G+ + ++
Sbjct: 30678 TWFRGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVLGTVDT---MLDV 30734
Query: 540 EGRNPPFFDIPLAPV 584
E ++ P D P P+
Sbjct: 30735 EIQDKP--DKPTGPI 30747
Score = 66.6 bits (161), Expect = 8e-11
Identities = 126/618 (20%), Positives = 228/618 (36%), Gaps = 39/618 (6%)
Frame = +3
Query: 3 PVKVTVGD----SASLQCQL----AGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVF 158
P KVT+ D SASL + G+ +G Y + + + T + + + V + V
Sbjct: 24233 PGKVTLTDVSQTSASLMWEKPEHDGGSRILG---YVVEMQPKGTEKWSVVAESKVCSAVV 24289
Query: 159 NQVDSNDSGEYICRAENSVGEVSSSTF---LTVQEQKLPPSFSRQLRDVQETVGLPVVFE 329
+ S + +A N G+ + ++ + PSF G + E
Sbjct: 24290 TGLSSGQEYHFRVKAYNEKGQSDPRVLGVPVIAKDLTIQPSFKLPFNTYSVQAGEDLKIE 24349
Query: 330 CAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGS 509
V G +SW KDG PLK + L+I ++++ G+Y+ TATN G+
Sbjct: 24350 IPVIGRPRPEISWVKDGEPLKQTTRVNVEKTATSTILHIKESNKDDFGKYTVTATNSAGT 24409
Query: 510 ASSSARLILTEGRNPPFFDIPLAPVDA-VVGESADFECHVTGTQPIKVAWAKDNREIRSG 686
A+ + +I+ E PP + V A V S + + G Q + + R+ +
Sbjct: 24410 ATENLSIIILEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISN--YIVEKRDTTTT 24467
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLI--------P 842
+ +S + I K+ G Q+ +A N GK +A L+ K ++ P
Sbjct: 24468 TWHMVSATVARTTIKITKLKMGSEYQFRIFAENRYGK---SAPLDSKPVIVQYPFKEPGP 24524
Query: 843 PSFTKKLSETVEE---------TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEIT 995
P S + ++ +G S + + + S+ W V+++ T +
Sbjct: 24525 PGTPFVTSVSKDQMLVQWHEPVNDGGSKVIGYHLEQKEKNSILW----VKLNKTPIQDTK 24580
Query: 996 FKNNALLLQVKKASMGDAGL-YTCKVSND-----AGSALCTSSIVIKEPKKPPVFDQHLT 1157
FK L D GL Y +VS + ++ + V ++P PP + +
Sbjct: 24581 FKTTGL----------DEGLEYEFRVSAENIVGIGKASKVSECFVARDPCDPPGRPEAIV 24630
Query: 1158 PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEF--KDVTKA 1331
+ + + GS +I ++ P R + EF + +
Sbjct: 24631 ITRNNVTLKWKKPAYDGGS---KITGYIVEKKDLPDGRWMKASFTNVLDTEFTVSGLVED 24687
Query: 1332 DAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTA 1511
++ A N AG+ + S+ T +D K V +V
Sbjct: 24688 QRYEFRVIARNAAGNFSEPSESTGAITARDEIDAPNASLDPKYKDV-------IVVHAGE 24740
Query: 1512 TFI--AKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVA 1685
TF+ A + G PIP++ W+K R+ I L ++D ++D G Y
Sbjct: 24741 TFVLEADIRGKPIPDIVWSKDGRELEETAARMEIKSTIQRTTLVVKDCIRSDGGQYILKL 24800
Query: 1686 FNKHGEIESNVNLQVNER 1739
N G + ++V +R
Sbjct: 24801 SNVGGTKTIPITVKVLDR 24818
Score = 63.2 bits (152), Expect = 8e-10
Identities = 55/201 (27%), Positives = 80/201 (39%), Gaps = 2/201 (0%)
Frame = +3
Query: 1134 PVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS--DRCSFSFANGTAVL 1307
P F Q L V V EG H+ G + W + G+ I S SF++G A L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 1308 EFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSI 1487
VTKA++G Y +A+N +G TS +++ F QS+
Sbjct: 66 TIPAVTKANSGRYSLRATNGSGQATSTAELLVTAETAPPN------------FTQRLQSM 113
Query: 1488 RVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSG 1667
V + + +V G P P VK+ + ++ I Q+G+ L I IFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+++ + + L N TL I +S +G Y C AT +A A ++L +G
Sbjct: 344 YRNTELVLPDEAVSIRGLSN-ETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIVLEDG- 401
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS--- 719
P + GE C G P V WA D+ I G+++ + S
Sbjct: 402 -TPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGT 460
Query: 720 --AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN 893
+H+ + D G Y C A N VG A++N++ PPS + + G
Sbjct: 461 TISHMNVTGPQIRDGGVYRCTARNSVGSAEYQARINVRG---PPSI--RAMRNITAVAGR 515
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
+ RV G S+ WYK+ + + P + ++ F+N L L + M D G Y C V
Sbjct: 516 DTLINCRVIGYPYYSIKWYKDAL-LLPDNHRQVVFENGTLKLTDVQKGM-DEGEYLCSVL 573
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHV-RGSEPIRIQWLKAGR 1250
L S V K PP+ P S G+ L + C V G PIRI W K G+
Sbjct: 574 --IQPQLSISQSVHVAVKVPPLIQPFEFP-PASIGQLLYIPCVVSSGDMPIRITWRKDGQ 630
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
I + + L+ V+ G+Y C ASN A + + + ++
Sbjct: 631 VIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPR---- 686
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGK-------WRQLNQ 1589
FV +P + + V G P P V W K + +
Sbjct: 687 -----------FVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGSPQQYHPVPL 735
Query: 1590 GGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG 1700
GR I + L IR + D G Y C A N G
Sbjct: 736 TGRTQILA---NSSLLIRHVLEEDMGYYLCQASNGVG 769
Score = 139 bits (349), Expect = 1e-32
Identities = 145/611 (23%), Positives = 236/611 (38%), Gaps = 26/611 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+K +G + L C L G+PE + WY+ + P + +N TL+ + SG
Sbjct: 319 LKTGIGSTVILSCALLGSPEFTIRWYRNTELVLPDEAVSIRGLSN-ETLLITSAQKSHSG 377
Query: 186 EYICRAENSVGEVSSSTFLTVQE--QKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C A + +++ ++ SFS ++ + E L CA G+ P +
Sbjct: 378 AYQCFATRKAQTAQDFAIIVLEDGTPRIVSSFSEKVVNPGEQFSL----MCAAKGAPPPT 433
Query: 360 VSWFKDGRPL-KDGPNIQTSFL----DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
V+W D P+ +DG + + ++ +N+ G Y CTA N +GSA A
Sbjct: 434 VTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNSVGSAEYQA 493
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
R+ + R PP + + AV G C V G + W KD + N++
Sbjct: 494 RINV---RGPPSIR-AMRNITAVAGRDTLINCRVIGYPYYSIKWYKD--ALLLPDNHRQV 547
Query: 705 YLENSAHLTILKVDKG-DTGQYTCYAVNEVGKDSCTAQLNIKERL-----IPPSFTKKLS 866
EN L + V KG D G+Y C + + QL+I + + +PP +
Sbjct: 548 VFENGT-LKLTDVQKGMDEGEYLCSVLIQ-------PQLSISQSVHVAVKVPPLI--QPF 597
Query: 867 ETVEETEGNSFRLEGRV-AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMG 1043
E + G + V +G PI + W K+ I + I K LQ+ S+
Sbjct: 598 EFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLK 657
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
G YTC SN A + ++++ P + V + + G L+C V G P
Sbjct: 658 HNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAG---VLNCSVDGYPPP 714
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLE-----FKDVTKADAGDYVCKASNVAGSDTSK 1388
++ W A P T +L + V + D G Y+C+ASN G+D SK
Sbjct: 715 KVMWKHAKGSGSPQQYHPVPLTGRTQILANSSLLIRHVLEEDMGYYLCQASNGVGTDISK 774
Query: 1389 SKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG 1568
S V S P + ++ G+ ++W KG
Sbjct: 775 S--------------MFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKG 820
Query: 1569 KW-----RQLNQGGRIFIHQKGDE--AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
R + I GDE + L+++ + DS + C A N +GE + L
Sbjct: 821 DTVIDPDRVMRYA--IATKDNGD+ DSG
Sbjct: 114 TVRQGSQVRLQVRVTGIPTPVVKFYR-DGAEIQSSLDFQISQEGELYSLLIAEAYPEDSG 172
Query: 1668 LYRCVAFNKHGEIESNVNLQV 1730
Y A N G S L V
Sbjct: 173 TYSVNATNSVGRATSTAELLV 193
Score = 63.2 bits (152), Expect = 8e-10
Identities = 110/511 (21%), Positives = 193/511 (37%), Gaps = 56/511 (10%)
Frame = +3
Query: 36 LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSV 215
L+ + G P VSW KG+ L + TLV +D+G+Y +N
Sbjct: 20019 LKIPIKGKPVPSVSWKKGEDPLATDTRVSVESSAVNTTLVVYDCRKSDAGKYTITLKNVA 20078
Query: 216 GEVSSS-TFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLK 392
G + T V + +P P+ FE + E +++ W G P
Sbjct: 20079 GTKEGTLTIKVVGKPGIPTG--------------PIKFEEVTA--EAVTLKW---GPPKD 20119
Query: 393 DGPNIQTSFL----DNV-------------ATLNIFQTDRSFAGQYSCTATNP--IGSAS 515
DG + T+++ D+V T + + + +A N +G
Sbjct: 20120 DGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVMRLHEGMEYTFRVSAENKYGVGEGL 20179
Query: 516 SSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNY 695
S ++ R+P FD+P AP + + +T T P K + Y
Sbjct: 20180 KSEPIV---ARHP--FDVPDAPPPPNIVDVRHDSVSLTWTDPRKTGGSPIT-------GY 20227
Query: 696 QISYLENSAHL--------------TILKVDKGDTGQYTCYAVN--EVGKDSCTAQLNIK 827
I + E ++ L + + +G ++ A+N VGK S ++ +
Sbjct: 20228 HIEFKERNSLLWKRANKTPIRMKDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVA 20287
Query: 828 -ERLIPPSFTKKLSET--------VEETEGNSFRLEGRVAGSQPI-SVAWYKNNVEIHPT 977
+ + PP + +S T E +L G + + + S +W K N P
Sbjct: 20288 LDPIDPPGKPEVISVTRNSVTLVWTEPKYDGGHKLTGYIVEKRELPSKSWTKANHVNVPD 20347
Query: 978 ANCEITFKNNALLLQVKKASMGDAGLYTCKV--SNDAGSALC----TSSIVIKEPKKPP- 1136
+T + + G Y +V N AG+ T +I+ K+ + P
Sbjct: 20348 CAFTVT-------------DLVEGGKYEFRVRAKNTAGAISAPSESTDTIICKDEYEAPT 20394
Query: 1137 -VFDQHLTP-VTVSEGEFLQLSC-HVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVL 1307
V D + +TV G+ + LS + G + W KAG++I+PSD + ++++
Sbjct: 20395 IVLDPTIKDGLTVKAGDTIILSAISILGKPLPKSSWSKAGKDIRPSDIVQITSTPTSSMI 20454
Query: 1308 EFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
K T+ DAG+Y A+N G+ + KVT
Sbjct: 20455 AVKYATRKDAGEYTITATNPFGTKSEHVKVT 20485
Score = 63.2 bits (152), Expect = 8e-10
Identities = 86/399 (21%), Positives = 147/399 (36%), Gaps = 20/399 (5%)
Frame = +3
Query: 48 LAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVS 227
+ G P V W + + A+ + ++ L+ V+ DSG+YI ENS G S
Sbjct: 21901 IKGRPAPEVKWTREHGESLDKASIES--TSSYTLLIIGNVNRFDSGKYILTIENSSGSKS 21958
Query: 228 SSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNI 407
+ + V + PP + + +V L GS+ + K K +
Sbjct: 21959 AFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWEPPLIDGGSKINNYIVEKRESTRKAYSTV 22018
Query: 408 QTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVD 587
T+ ++ Q S+ + IG + +A + R P I L V
Sbjct: 22019 TTNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLVDVT 22078
Query: 588 AVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS---------------- 719
+ ++W K + GG+ + Y+
Sbjct: 22079 R---------------NSVSLSWEKPEHD---GGSRILGYIVEMQSKGSDKWVTCATVKV 22120
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI----KERLIPPSFTKKLSETVEETE 887
TI + +G+ + A NE G S QL++ K+ +IPP+F K L T
Sbjct: 22121 TEATITGLIQGEEYSFRVSAQNEKGI-SDPRQLSVPVIAKDLVIPPAF-KLLFTTFTVLA 22178
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCK 1067
G +++ G +V W+K++V + T N LL +K+A D G Y K
Sbjct: 22179 GEDLKVDVPFTGRPTPAVTWHKDDVPLKQTTRVNAESTENNSLLTIKEACREDVGHYIVK 22238
Query: 1068 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEF 1184
++N AG A T ++++ + PP + VT F
Sbjct: 22239 LTNSAGEATETLNVIVLDKPGPPTGPVKMEEVTADSVTF 22277
Score = 61.2 bits (147), Expect = 3e-09
IdentitiEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLT 878
Query: 1728 VNERKKQEKIE 1760
V E ++E
Sbjct: 879 VQEPPDPPELE 889
Score = 99.4 bits (246), Expect = 1e-20
Identities = 132/571 (23%), Positives = 215/571 (37%), Gaps = 25/571 (4%)
Frame = +3
Query: 42 CQLAGTPEIGVSWY--KGDTKLRPTATYKMHFRNNVATLVFNQVDSND---SGEYICRAE 206
C AG+P + WY GD +H + F+ N +Y C AE
Sbjct: 42 CPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTAE 101
Query: 207 NSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGS--EPIS-VSWFKD 377
N+ G++ S + P ++ ++ D + G VF+C + S E +S VSW KD
Sbjct: 102 NAAGKIRSPNIRVKAVFREP--YTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKD 159
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFA-GQYSCTATNPIGS---ASSSARLILTE- 542
+ F+ + L I + A Y C + S+ ARL +T+
Sbjct: 160 TVSIIPENRF---FITHHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDP 216
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ P + G + + C +G + W KD R + + + +
Sbjct: 217 AESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSR----WTKRIT 272
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
LT+ + D+G Y C +N G T L + + L KKL + G++
Sbjct: 273 GLTVSDLRTEDSGTYICEVINTFGSAEATGTLTVIDPLHVTLTPKKLKTGI----GSTVI 328
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L + GS ++ WY+N + P I +N LL + A +G Y C + A
Sbjct: 329 LSCALLGSPEFTIRWYRNTELVLPDEAVSIRGLSNETLL-ITSAQKSHSGAYQCFATRKA 387
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI-- 1256
+A + IV+++ P + V+ GE L C +G+ P + W I
Sbjct: 388 QTAQDFAIIVLED--GTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVR 445
Query: 1257 KPSDRCS-FSFANGTAV--LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
S R + ++ ++GT + + D G Y C A N GS ++++
Sbjct: 446 DGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNSVGSAEYQARIN--------- 496
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTA-----TFI-AKVGGDPIPNVKWTKGKWRQLNQ 1589
V P SIR + TA T I +V G P ++KW K L
Sbjct: 497 -------------VRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDA-LLLPD 542
Query: 1590 GGRIFIHQKGDEAKLEIRDTTK-TDSGLYRC 1679
R + + G L++ D K D G Y C
Sbjct: 543 NHRQVVFENG---TLKLTDVQKGMDEGEYLC 570
Score = 84.7 bits (208), Expect = 3e-16
Identities = 104/439 (23%), Positives = 175/439 (39%), Gaps = 24/439 (5%)
Frame = +3
Query: 15 TVGDSASLQCQLA-GTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
++G + C ++ G I ++W K + + + + +++L + V +G Y
Sbjct: 603 SIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNY 662
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A N+ VS L V ++PP F Q + G V C+V G P V W
Sbjct: 663 TCIASNAAATVSRERQLIV---RVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWK 719
Query: 372 K---DGRPLKDGP---NIQTSFLDNVATL--NIFQTDRSFAGQYSCTATNPIGSASSSAR 527
G P + P +T L N + L ++ + D G Y C A+N +G+ S +
Sbjct: 720 HAKGSGSPQQYHPVPLTGRTQILANSSLLIRHVLEEDM---GYYLCQASNGVGTDISKSM 776
Query: 528 LILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGG--NYQI 701
+ + P A+ G + + C G +PI + W K + I Y I
Sbjct: 777 FLTV--KIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAI 834
Query: 702 SYLENS----AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE 869
+ +N + L + D+GD+ ++C+A+N G+D QL ++E PP
Sbjct: 835 ATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPEL------ 888
Query: 870 TVEETEGNSFRLE--GRVAGSQPIS--VAWYKNNVEI----HPTANCEITFKNNALLLQV 1025
+ E + S L R G+ I+ YKN + T N T N A ++ +
Sbjct: 889 EIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTI-NQANIVDL 947
Query: 1026 KKASMGDAGLYTC-KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCH 1202
AS+ +Y+ K+ S T S P PP+ D L PVT es = 91/416 (21%), Positives = 157/416 (37%), Gaps = 22/416 (5%)
Frame = +3
Query: 201 AENSVGEVSSSTF---LTVQEQKLPPSF---SRQLRDVQETVGLPVVFECAVSGSEPISV 362
A N+ GE + + V+++ PP + R+ VG + + G V
Sbjct: 17208 AVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIRVGDTLRLSAIIKGVPFPKV 17267
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+ R I + + + L I G YS T NP GS + S ++++
Sbjct: 17268 TWKKEDRAAPTKARIDVTPVGS--KLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLV-- 17323
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIK------VAWAKDNREIRSGGNYQIS 704
D P P D V E C++T +P+ + + +++ S +S
Sbjct: 17324 ------LDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERKDVASTEWSPLS 17377
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKD---SCTAQLNIKERLIPPSFTKKLSET- 872
+++G+ + A N+ G+ + + L PP K L
Sbjct: 17378 TTSKKKSHLAKHLNEGNQYVFRVAAENQYGRGPFVETPKPIKAVDPLHPPGPPKNLHHVD 17437
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKN-NALLLQVKKASMGDA 1049
V++TE + + G PI+ + E P I FK L V G
Sbjct: 17438 VDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTPDW---IKFKTVTNLACVVTGLQQGKT 17494
Query: 1050 GLYTCKVSNDAGSALCTSSIVIKEPKK--PPVFD---QHLTPVTVSEGEFLQLSCHVRGS 1214
+ K N G L ++I I+ +K PP + + + + V G ++ +RG
Sbjct: 17495 YRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGV 17554
Query: 1215 EPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
+W G EIK + + N ++VL K+ + D G+Y SN AG+ T
Sbjct: 17555 PIPTAKWTTDGNEIKTDEHYTVETDNFSSVLTIKNCLRKDTGEYQITVSNAAGTKT 17610
Score = 60.1 bits (144), Expect = 7e-09
Identities = 101/489 (20%), Positives = 171/489 (34%), Gaps = 23/489 (4%)
Frame = +3
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
G +VSW KDG+ LK+ + S V +L I + R G Y +N GS +
Sbjct: 25437 GRPQATVSWKKDGQTLKETTRVNVSSSKTVTSLIIKEASREDVGTYELCVSNSAGSVTVP 25496
Query: 522 ARLILTEGRNPPF-FDIPLAPVDAVV----GESADFECHVTGTQPIKVAWAKDNREIRSG 686
+I+ + PP I D + D C ++ + + RE S
Sbjct: 25497 ITVIVLDKPGPPGPIHIDEVSCDNITISWNPPEYDGGCQISN-------YIVEKRETTST 25549
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLI-----PPSF 851
+ +S + I+++ G Q+ A N GK S + + PP
Sbjct: 25550 TWHVVSQAVARTSIKIVRLVTGSEYQFRVCAENRFGKSSYSESSAVVAEYPFSPPGPPGT 25609
Query: 852 TKKLSET---------VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKN 1004
K + T V +G S L + + S+ W K N + +++ +
Sbjct: 25610 PKVVHATKSTMLVTWQVPVNDGGSRVLGYHLEYKERSSILWSKANKTLIADTQMKVSGLD 25669
Query: 1005 NALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS---IVIKEPKKPPVFDQHLTPVTVSE 1175
L+ + Y N AG C+ S + ++P PP +T +T
Sbjct: 25670 EGLMYE-----------YHVYAENIAGIGKCSKSCEPVPARDPCDPP-GQPEVTNITRKS 25717
Query: 1176 GEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFAN-GTAVLEFKDVTKADAGDYVC 1352
H G I ++ RE+ +F N E ++T+ ++
Sbjct: 25718 VSLKWSKPHYDGGAKI-TGYIIERRELPDGRWLKCNFTNVPETYFEVTELTEDQRYEFRV 25776
Query: 1353 KASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVG 1532
A N A S + S+ T +D K V ++ V++ A V
Sbjct: 25777 FARNAADSISEPSESTGPITVKDDVEAPRIMMDVKFRDVIVVKAGEVLK-----INADVA 25831
Query: 1533 GDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIES 1712
G P+P + W K ++ + R I L ++D + DSG Y N G
Sbjct: 25832 GRPLPIISWAK-DGVEIEERARTEIVSTDYTTLLTVKDCVRRDSGQYVLTVKNVAGTRSM 25890
Query: 1713 NVNLQVNER 1739
VN +V ++
Sbjct: 25891 AVNCKVLDK 25899
Score = 58.9 bits (141), Expect = 2e-08
Identities = 87/375 (23%), Positives = 140/375 (37%), Gaps = 21/375 (5%)
Frame = +3
Query: 336 VSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
+ G V W ++ D +I+++ + L I +R +G+Y T N GS S
Sbjct: 21901 IKGRPAPEVKWTREHGESLD
Sbjct: 948 HPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPM-DVTLQPVT------------ 994
Query: 1203 VRGSEPIRIQWLKAGREIK 1259
S+ I++ W +E++
Sbjct: 995 ---SQSIQVTWKAPKKELQ 1010
Score = 66.6 bits (161), Expect = 8e-11
Identities = 110/502 (21%), Positives = 181/502 (36%), Gaps = 20/502 (3%)
Frame = +3
Query: 285 LRDVQETVGLPVVFECAVSGSEPISVSWF-KDGRPLKDGPNIQTSFLDNVATLNIFQTD- 458
L+ V + + VV C +GS ++ W+ G + D P+I+ + L F
Sbjct: 27 LQQVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSA 86
Query: 459 -RSFA--GQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVT 629
SF Y CTA N G S + R P + + + ++ G A F+C +
Sbjct: 87 FNSFIHDNDYFCTAENAAGKIRSPNIRVKAVFREP--YTVRVEDQRSMRGNVAVFKCLIP 144
Query: 630 GTQP---IKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDT-GQYTCYAVNEVG- 794
+ V+W KD I + ++ + L I V K D Y C ++
Sbjct: 145 SSVQEYVSVVSWEKDTVSIIPENRF---FITHHGGLYISDVQKEDALSTYRCITKHKYSG 201
Query: 795 --KDSCTAQLNIKE--RLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNV 962
+ S A+L++ + IP S+ V G++ L +G ++ W K+
Sbjct: 202 ETRQSNGARLSVTDPAESIPTILDGFHSQEV--WAGHTVELPCTASGYPIPAIRWLKDGR 259
Query: 963 EIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVF 1142
+ + + L V D+G Y C+V N GSA T ++ + +P
Sbjct: 260 PLPADSR----WTKRITGLTVSDLRTEDSGTYICEVINTFGSAEATGTLTVIDP-----L 310
Query: 1143 DQHLTP--VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFK 1316
LTP + G + LSC + GS I+W + + P + S + +L
Sbjct: 311 HVTLTPKKLKTGIGSTVILSCALLGSPEFTIRWYRNTELVLPDEAVSIRGLSNETLL-IT 369
Query: 1317 DVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVV 1496
K+ +G Y C A+ A + + + DG VS V
Sbjct: 370 SAQKSHSGAYQCFATRKAQTAQDFAIIVLE--------------DGTPRIVSSFSEKVVN 415
Query: 1497 EKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGG-RIFIHQKGDEAKLEIRDTTK---TDS 1664
+ + G P P V W + G R + D + + T D
Sbjct: 416 PGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDG 475
Query: 1665 GLYRCVAFNKHGEIESNVNLQV 1730
G+YRC A N G E + V
Sbjct: 476 GVYRCTARNSVGSAEYQARINV 497
>ref|XP_539325.2| PREDICTED: similar to obscurin, cytoskeletal calmodulin and
titin-interacting RhoGEF [Canis familiaris].
Length = 4467
Score = 144 bits (362), Expect = 4e-34
Identities = 141/557 (25%), Positives = 223/557 (40%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G +A+L+C L+ T V W +GD LRP Y M V LV + DSG+Y
Sbjct: 1609 VLEGSAATLRCVLS-TVAAPVQWRRGDEVLRPGGKYSMRQDGPVLELVVRDLRPQDSGQY 1667
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C G+ + L V+ Q P F +LR+ + T G C +S + P V W
Sbjct: 1668 SC----CFGDKMTLATLNVKAQ--PTEFIGRLRNKEATEGATATLRCELSKAAP--VEWR 1719
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K L+ G + V L I +G+YSC G ++A +LT
Sbjct: 1720 KGPEALRAGDRVSLRQDGAVCELQIRGLAVEDSGEYSCVC----GQERTAA--VLTVREL 1773
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
P F L +A G +A C ++ P++ W K +R+G + L
Sbjct: 1774 PTKFTKSLRNEEASEGATATLRCELSKAAPVE--WRKGPEALRAGDRVSLRQDGAVCELQ 1831
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
I + D+G+Y+C G++ A L + R +P FTK L + E TEG + L
Sbjct: 1832 IRGLAVEDSGEYSCVC----GQERTAAVLTV--RALPAKFTKGLRKE-EATEGATATLRC 1884
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
++ + P V W K + + LQ++ ++ D+G Y+C + +A
Sbjct: 1885 ELSKAAP--VEWRKGPEALRAGDRVSLRQDGAVCELQIRGLAVEDSGEYSCVCGQERTAA 1942
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
+ T KASIEST--SSYTLLIIGNVNRFDSGKYILTIENSSGSKS 21958
Query: 516 SSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI---RSG 686
+ N D P P D V E +T P+ +K N I R
Sbjct: 21959 AFV--------NVRVLDTPGPPQDLKVKEVTKTSVTLTWEPPLIDGGSKINNYIVEKRES 22010
Query: 687 GNYQISYLENSAHLTILKVDKGDTG---QYTCYAVNE--VGKDSCTAQ-LNIKERLIPPS 848
S + + H T KVD+ G + A NE +G + TA+ + ER +PP
Sbjct: 22011 TRKAYSTVTTNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPG 22070
Query: 849 F---------TKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFK 1001
+ LS E +G S R+ G + Q K + + A ++T
Sbjct: 22071 KITLVDVTRNSVSLSWEKPEHDGGS-RILGYIVEMQS------KGSDKWVTCATVKVTEA 22123
Query: 1002 NNALLLQVKKASMGDAGLYTCKVSNDAGSA---LCTSSIVIKEPKKPPVFDQHLTPVTVS 1172
L+Q G+ + N+ G + + ++ K+ PP F T TV
Sbjct: 22124 TITGLIQ------GEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFTTFTVL 22177
Query: 1173 EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVC 1352
GE L++ G + W K +K + R + ++L K+ + D G Y+
Sbjct: 22178 AGEDLKVDVPFTGRPTPAVTWHKDDVPLKQTTRVNAESTENNSLLTIKEACREDVGHYIV 22237
Query: 1353 KASNVAGSDTSKSKV 1397
K +N AG T V
Sbjct: 22238 KLTNSAGEATETLNV 22252
Score = 58.2 bits (139), Expect = 3e-08
Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Frame = +3
Query: 240 LTVQEQKLPPSFS-----RQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPN 404
+T+ + +PP + L V+ G V + V G +VSW KDG LK
Sbjct: 19301 VTIMAESVPPRIELSVAMKSLLTVK--AGTNVCLDATVFGKPKPTVSWKKDGTLLKPSEG 19358
Query: 405 IQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
I+ + N+ TL +F R +G Y+ TA NP GS S++ +L + + PP
Sbjct: 19359 IKMAMKRNLCTLELFSVTRKDSGDYTITAENPSGSKSATIKLKVLDKPGPP 19409
Score = 57.8 bits (138), Expect = 4e-08
Identities = 76/356 (21%), Positives = 129/356 (36%), Gaps = 10/356 (2%)
Frame = +3
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W ++ D +Q N L+I DR+ AG+Y N GS S+ + +
Sbjct: 24073 ITWSREEGEFTD--KVQIEKAANYTQLSIDNCDRNDAGKYVLKLENSSGSKSAFVTVKV- 24129
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAK------DNREIRSGGNYQI 701
D P P + V E + P+ AK D RE +
Sbjct: 24130 -------LDTPGPPQNLAVKEVRKDSVLLVWDPPLIDGGAKVKNYVIDKRESTRKAYANV 24182
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET-VE 878
S + L + + +G + A NE G ++ + PPS K++ T V
Sbjct: 24183 SNKCSKTSLKVENLTEGAIYYFRVMAENEFGIGVPVETVDAVKASEPPSPPGKVTLTDVS 24242
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
+T + + G I Y ++ T + ++ V S G +
Sbjct: 24243 QTSASLMWEKPEHDGGSRI--LGYVVEMQPKGTEKWSVVAESKVCSAVVTGLSSGQEYHF 24300
Query: 1059 TCKVSNDAGSA---LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRI 1229
K N+ G + + ++ K+ P F +V GE L++ V G I
Sbjct: 24301 RVKAYNEKGQSDPRVLGVPVIAKDLTIQPSFKLPFNTYSVQAGEDLKIEIPVIGRPRPEI 24360
Query: 1230 QWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
W+K G +K + R + + +L K+ K D G Y A+N AG+ T +
Sbjct: 24361 SWVKDGEPLKQTTRVNVEKTATSTILHIKESNKDDFGKYTVTATNSAGTATENLSI 24416
Score = 57.4 bits (137), Expect = 5e-08
Identities = 71/292 (24%), Positives = 107/292 (36%), Gaps = 3/292 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VT D A CQL+ + V WY+ +++ YK ++ L+ +D EY
Sbjct: 12851 VTEFDDAVFSCQLS-REKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEY 12909
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C V + S L V+E +P R +D+ E G VVF A + + V W
Sbjct: 12910 AC----GVDDRKSRARLFVEE--IPVEIIRPPQDILEAPGADVVF-LAELNKDKVEVQWL 12962
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K+ + G+ P F + L +EG L C + + P ++W K ++ DR
Sbjct: 1943 VLTVRAL------PAKFTKGLRKEEATEGATATLRCELSKAAP--VEWRKGPEALRAGDR 1994
Query: 1272 CSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVD 1451
S L+ + + D+G+Y C V G + + + +T
Sbjct: 1995 VSLRQDGAVCELQIRGLAVEDSGEYSC----VCGQERTAAVLTVRELPTK---------- 2040
Query: 1452 GKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAK 1631
F ++ E TAT ++ V+W KG L G R+ + Q G +
Sbjct: 2041 ----FTKSLRNEEASEGATATLRCEL--SKAAPVEWRKGP-EALRAGDRVSLRQDGAVCE 2093
Query: 1632 LEIRDTTKTDSGLYRCV 1682
L+IR DSG Y CV
Sbjct: 2094 LQIRGLAMEDSGEYSCV 2110
Score = 141 bits (355), Expect = 3e-33
Identities = 129/465 (27%), Positives = 200/465 (43%), Gaps = 2/465 (0%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+ T G +A+L+C+L+ V W KG LR + V L + DSGE
Sbjct: 1961 EATEGATATLRCELSKAAP--VEWRKGPEALRAGDRVSLRQDGAVCELQIRGLAVEDSGE 2018
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y C G+ ++ LTV+E LP F++ LR+ + + G C +S + P V W
Sbjct: 2019 YSCVC----GQERTAAVLTVRE--LPTKFTKSLRNEEASEGATATLRCELSKAAP--VEW 2070
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K L+ G + V L I +G+YSC G ++A +LT
Sbjct: 2071 RKGPEALRAGDRVSLRQDGAVCELQIRGLAMEDSGEYSCVC----GQERTAA--VLTVRA 2124
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQP-IKVAWAKDNREIRSGGNYQISYLENSAH 725
F PL + A G S C ++ QP V W+K E+++ + +
Sbjct: 2125 AQVVFKEPLRSLQAKEGTSVTLRCELS--QPGATVVWSKGGLELQADSRREPRLQGPTVE 2182
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + + +GD+G+YTC G S +A L I P F ++L E E EG + L
Sbjct: 2183 LVLRDLHRGDSGEYTCAC----GLQSTSATLTITAA--PVQFLREL-EAQEVDEGATACL 2235
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
++ + SV W K ++++ P A ++ K + L V+ A DAG YTC D G
Sbjct: 2236 RCELS-QECASVDWRKGSLQLFPCAKYQMVQKGTTVELLVRSAEQEDAGHYTC----DTG 2290
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSE-PIRIQWLKAGREIKP 1262
T+S+ ++ + PVF + L G L C + +E + +QWLK G E+
Sbjct: 2291 HTQSTASLSVRACR--PVFQEELQSTEQEAGGVAWLHCQLSKAETDVPVQWLKEGVELHL 2348
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
S + T L + D G+YVC VAG + + V
Sbjct: 2349 SPKYEIRRVGTTCELLIHGLEPKDTGEYVC----VAGGQKTMASV 2389
Score = 137 bits (346), Expect = 3e-32
Identities = 137/557 (24%), Positives = 229/557 (41%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+ T G +A+L+C+L+ V W KG LR + V L + DSGE
Sbjct: 1697 EATEGATATLRCELSKAAP--VEWRKGPEALRAGDRVSLRQDGAVCELQIRGLAVEDSGE 1754
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y C G+ ++ LTV+E LP F++ LR+ + + G C +S + P V W
Sbjct: 1755 YSCVC----GQERTAAVLTVRE--LPTKFTKSLRNEEASEGATATLRCELSKAAP--VEW 1806
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K L+ G + V L I +G+YSC G ++A +LT
Sbjct: 1807 RKGPEALRAGDRVSLRQDGAVCELQIRGLAVEDSGEYSCVC----GQERTAA--VLTVRA 1860
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
P F L +A G +A C ++ P++ W K +R+G + L
Sbjct: 1861 LPAKFTKGLRKEEATEGATATLRCELSKAAPVE--WRKGPEALRAGDRVSLRQDGAVCEL 1918
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
I + D+G+Y+C G++ A L + R +P FTK L + E TEG + L
Sbjct: 1919 QIRGLAVEDSGEYSCVC----GQERTAAVLTV--RALPAKFTKGLRKE-EATEGATATLR 1971
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
++ + P+ W K + + LQ++ ++ D+G Y+C + +
Sbjct: 1972 CELSKAAPVE--WRKGPEALRAGDRVSLRQDGAVCELQIRGLAVEDSGEYSCVCGQERTA 2 Q + L I G+Y A + AR L
Sbjct: 12963 KNNMIIVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKD------KEARAKLELAAA 13016
Query: 552 PPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P I A D VV G+ + W K+N + S +
Sbjct: 13017 PK---IKTADQDLVVDVGQPLTMVVPYDAFPKAEAEWFKENEPLSSK---TVDTTAEQTS 13070
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP-PSFTKKLSETVE 878
ILK K D G+Y N+ GK +N+K +P P +++ET +
Sbjct: 13071 FRILKAKKEDKGRYKVVLQNKHGK--AEGFINLKVIDVPGPVRNLEVTETFD 13120
Score = 56.6 bits (135), Expect = 8e-08
Identities = 61/240 (25%), Positives = 91/240 (37%), Gaps = 16/240 (6%)
Frame = +3
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLP--------PSFSRQLRDVQETVGLPVVFECAVS 341
E+ + EN GE S + + E P P F +LR++ C V+
Sbjct: 30913 EFRVKCENLGGE---SEWSEISEPVTPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVT 30969
Query: 342 GSEPISVSWFKDGRPL-KDGPNIQTS-FLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
G V W++ G+ + DG + F L I A Y ATN GS S
Sbjct: 30970 GHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVS 31029
Query: 516 SSARLILTEGRNPPFFDIP-----LAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIR 680
+A L E P +P + V A+ GE + +G + W K I
Sbjct: 31030 GTASL---EVEVPAKIHLPKNLEGMGAVHALRGEVISIKIPFSGKPDPVITWQKGQDLID 31086
Query: 681 SGGNYQISYLENSAHLTILK-VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK 857
+ G+YQ+ + L V++ D G Y A N G D T +L++ + PP K
Sbjct: 31087 NNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVK 31146
Score = 55.5 bits (132), Expect = 2e-07
Identities = 31/87 (35%), Positives = 44/87 (50%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G + L + G P+ VSW K T L+P+ KM + N+ TL V DSG+Y
Sbjct: 19324 VKAGTNVCLDATVFGKPKPTVSWKKDGTLLKPSEGIKMAMKRNLCTLELFSVTRKDSGDY 19383
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPS 272
AEN G S++ L V ++ PP+
Sbjct: 19384 TITAENPSGSKSATIKLKVLDKPGPPA 19410
Score = 54.3 bits (129), Expect = 4e-07
Identities = 98/467 (20%), Positives = 180/467 (38%), Gaps = 40/467 (8%)
Frame = +3
Query: 117 YKMHFRNNVATLVFNQVDSNDSGEYICRAE----NSVGEVSSSTFLTVQEQKLPPSFSRQ 284
Y++H + F D +Y R + E S ST ++L
Sbjct: 29406 YRVHTNATIRNNEFTVTDLKMGQKYSFRVAAVNVKGMSEYSESTAEIEPVERLEIPDLEL 29465
Query: 285 LRDVQETV----GLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQ 452
D+++TV G + +VSG P ++W K G L I T+ ++ + L + +
Sbjct: 29466 ADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKKGIDLASRAIIDTT--ESYSLLIVDK 29523
Query: 453 TDRSFAGQYSCTATNPIG--SASSSARLILTEGRNPPF-------------FDIPL---- 575
+R AG+Y+ A N G SA+ ++ T G P +++P
Sbjct: 29524 VNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEVPTIDGG 29583
Query: 576 APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA--HLTILKVDK 749
APV+ + E + + K K ++ + Y+IS L A + +L +
Sbjct: 29584 APVNNYIIEKRE-----AAMRAFKTVTTKCSKTL-----YRISGLIEGAMYYFRVLPENI 29633
Query: 750 GDTGQ----YTCYAVNEVGKDSCTAQL-NIKERLIPPSFTKKLSETVEETEGNSFRLEGR 914
G+ V+EV ++ ++ + + ++ K L + G + LE
Sbjct: 29634 YGIGEPCETSDAVLVSEVPLVPTKLEVVDVTKSTVTLAWEKPLYDGGSRLTG--YVLEAC 29691
Query: 915 VAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSAL 1094
AG++ W K +T K L V + G+ L+ + N+ G +
Sbjct: 29692 RAGTE----RWMK-----------VVTLKPTVLEHTVISLNEGEQYLFRVRAQNEKGVSE 29736
Query: 1095 ---CTSSIVIKEPKKPPVFDQHLTP---VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
+++ +++ + P D P + V G ++L + G P W AG ++
Sbjct: 29737 PREIVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKL 29796
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
+ S+R + A L ++ T D GDYV + NV G+ + KV
Sbjct: 29797 RESERVTVETHTKVAKLTIRETTIKDTGDYVLELKNVTGTTSETIKV 29843
Score = 53.9 bits (128), 029
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
A+ T ++E P F + L SEG L C + + P+ +W K ++ D
Sbjct: 2030 AVLT----VRE--LPTKFTKSLRNEEASEGATATLRCELSKAAPV--EWRKGPEALRAGD 2081
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
R S L+ + + D+G+Y C V G + + + +T
Sbjct: 2082 RVSLRQDGAVCELQIRGLAMEDSGEYSC----VCGQERTAAVLTVRA------------- 2124
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
++ F +S++ E T+ T ++ P V W+KG +L R +G
Sbjct: 2125 -AQVVFKEPLRSLQAKEGTSVTLRCELS-QPGATVVWSKGGL-ELQADSRREPRLQGPTV 2181
Query: 1629 KLEIRDTTKTDSGLYRC 1679
+L +RD + DSG Y C
Sbjct: 2182 ELVLRDLHRGDSGEYTC 2198
Score = 137 bits (344), Expect = 5e-32
Identities = 143/560 (25%), Positives = 223/560 (39%), Gaps = 1/560 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFR-NNVATLVFNQVDSNDS 182
V+V G SA+ C+++ V W+ T L P ++ + L Q+ DS
Sbjct: 1427 VEVREGASATFSCRISPADYGPVHWFLDKTPLHPNELNEIEVQPGGYHVLTLRQLALKDS 1486
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G A G+ +S L V E+ P FSR+L D T G + C ++ + SV
Sbjct: 1487 GTIHFEA----GDQRASATLRVTEK--PSVFSRELTDTTVTEGEELTLVCEITTLDG-SV 1539
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W KDG+ L+ Q S + A L I G+Y C A G + SS+ I+
Sbjct: 1540 CWTKDGKVLRPSARCQLSQEGHRAQLIITGATMQDGGRYKCEA----GDSWSSS--IVRV 1593
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L +D + G +A C V T V W + + +R GG Y +
Sbjct: 1594 HARPVCFREGLQDLDVLEGSAATLRC-VLSTVAAPVQWRRGDEVLRPGGKYSMRQDGPVL 1652
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + + D+GQY+C G A LN+K + P F +L E TEG +
Sbjct: 1653 ELVVRDLRPQDSGQYSCC----FGDKMTLATLNVKAQ--PTEFIGRL-RNKEATEGATAT 1705
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L ++ + P V W K + + LQ++ ++ D+G Y+C +
Sbjct: 1706 LRCELSKAAP--VEWRKGPEALRAGDRVSLRQDGAVCELQIRGLAVEDSGEYSCVCGQER 1763
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
+A+ T ++E P F + L SEG L C + + P ++W K ++
Sbjct: 1764 TAAVLT----VRE--LPTKFTKSLRNEEASEGATATLRCELSKAAP--VEWRKGPEALRA 1815
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
DR S L+ + + D+G+Y C V G + + + +T
Sbjct: 1816 GDRVSLRQDGAVCELQIRGLAVEDSGEYSC----VCGQERTAAVLTVRALPAK------- 1864
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
F + E TAT ++ V+W KG L G R+ + Q G
Sbjct: 1865 -------FTKGLRKEEATEGATATLRCEL--SKAAPVEWRKGP-EALRAGDRVSLRQDGA 1914
Query: 1623 EAKLEIRDTTKTDSGLYRCV 1682
+L+IR DSG Y CV
Sbjct: 1915 VCELQIRGLAVEDSGEYSCV 1934
Score = 133 bits (334), Expect = 7e-31
Identities = 145/553 (26%), Positives = 228/553 (41%), Gaps = 2/553 (0%)
Frame = +3
Query: 27 SASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAE 206
S L C P+ V WYK DT L P+ +KM ++A L ++ D+G Y C+A
Sbjct: 839 SVVLSCDFKPPPK-AVQWYKEDTPLAPSEKFKMMLEGHMAELRILRLTPADAGIYRCQA- 896
Query: 207 NSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRP 386
G SS +TV+ +++ + ++ L+D Q T F C +S E V W +G P
Sbjct: 897 ---GSAQSSAQVTVEAREV--TVTQPLQDAQVTEEGRACFSCELS-HEDEEVEWSLNGAP 950
Query: 387 LKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFD 566
L + + + TL + + R G T + S SA L P F
Sbjct: 951 LYNDSFHEITHEGRCHTLVLKRVRRVDTG------TVRVSSPKVSATARLEVKAKPVVFL 1004
Query: 567 IPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVD 746
L V A + +C V+ Q V W KD+ E+ Y + + L + +
Sbjct: 1005 KALDDVSAEERGTLALQCExpect = 5e-07
Identities = 61/288 (21%), Positives = 103/288 (35%), Gaps = 1/288 (0%)
Frame = +3
Query: 267 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNI 446
P + ++R + G F V V W+ +G L++ I + V TL I
Sbjct: 32398 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 32457
Query: 447 FQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHV 626
+G Y TN G AS A L +T G + D V S E +
Sbjct: 32458 LDCHIDDSGTYRAVCTNYKGEASDYATLDVTGG---DYTTYASQRRDEQVPRSVFPE--L 32512
Query: 627 TGTQPIKVAWAKDNREIRSGGNY-QISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDS 803
T T+ V+ K E+ + + ++ L ++ + + + A+ E +
Sbjct: 32513 TRTEAYAVSSFKKTSEMEASSSVREMKSLMTETRESLSSYEHHASAEMKSAAIEEKSLEE 32572
Query: 804 CTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTAN 983
+ IK L TK S TV EG S R G +V W + I +A
Sbjct: 32573 KSTHRKIKTTLAARILTKPRSITV--YEGESARFSCDTDGEPVPTVTWLRGGQVISTSAR 32630
Query: 984 CEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPK 1127
++T ++ D G Y+ V N G ++ +++ +
Sbjct: 32631 HQVTTSKYKSTFEISSVQASDEGNYSVVVENSDGRQEAQFTLTVQKAR 32678
Score = 53.5 bits (127), Expect = 7e-07
Identities = 32/100 (32%), Positives = 46/100 (46%)
Frame = +3
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ ++V K+P P D + V EGE L + R + W K G+E+K SDR +
Sbjct: 14392 SENVVAKDPDCRPTIDLETHDIVVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 14451
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
+ +A LE +ADAG Y N GS T+ V
Sbjct: 14452 MKNDHISAHLEVPKSVRADAGIYTVTLENKLGSATASINV 14491
Score = 52.8 bits (125), Expect = 1e-06
Identities = 62/273 (22%), Positives = 109/273 (39%), Gaps = 23/273 (8%)
Frame = +3
Query: 474 QYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVA 653
Q+ A N G +S S +P F + ++PVD + D+ VT + I +
Sbjct: 27845 QFRVFAENSAGLSSPS---------DPSKFTLAVSPVDPP--GTPDY-IDVT-RETITLK 27891
Query: 654 WAKDNREIRSGGNYQISYL-----------------ENSAHLTILKVDKGDTGQYTCYAV 782
W N +R GG+ ++Y + T+ + GD ++ A
Sbjct: 27892 W---NPPLRDGGSKIVAYSIEKRQGSDRWTRCNFTDVSECQYTVTGLSPGDRYEFRIIAR 27948
Query: 783 NEVGKDSCTAQ----LNIKERLIPPS--FTKKLSETVEETEGNSFRLEGRVAGSQPISVA 944
N VG S +Q + ++ + P+ F + + + G S R++ V G V
Sbjct: 27949 NAVGTISPPSQSSGVIMTRDENVAPTVEFGPEYFDGITIKSGESLRIKALVQGRPVPRVT 28008
Query: 945 WYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEP 1124
W+K+ VEI N EIT + L V+ A+ G+Y + N +GS ++ +++
Sbjct: 28009 WFKDGVEIEKKMNMEITDVLGSTSLFVRDATRDHRGVYRVEAKNASGSTKAEITVRVQDT 28068
Query: 1125 KKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
PV T +T + + H G P+
Sbjct: 28069 PGKPVGPIRFTNITGEKMTLWWDAPHNDGCAPV 28101
Score = 52.0 bits (123), Expect = 2e-06
Identities = 50/236 (21%), Positives = 92/236 (38%), Gaps = 16/236 (6%)
Frame = +3
Query: 165 VDSNDSGEYI--CRAENSVGEVSSS---TFLTVQEQKLPPSFSRQL---RDVQETVGLPV 320
+ N+ +Y+ RA+N G T +TVQ+ ++ P+ + + G PV
Sbjct: 29714 ISLNEGEQYLFRVRAQNEKGVSEPREIVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPV 29773
Query: 321 VFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNP 500
++G P + SWF G L++ + VA L I +T G Y N
Sbjct: 29774 ELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIKDTGDYVLELKNV 29833
Query: 501 IGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIR 680
G+ S + ++I+ + PP I + +DA + + G P+ + + R+
Sbjct: 29834 TGTTSETIKVIILDKPGPPSGPIKVDEIDATSVTISWGPPELDGGAPLS-GYVVEQRDAH 29892
Query: 681 SGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDS--------CTAQLNI 824
G +S + ++ +G+ + A N G S C + +NI
Sbjct: 29893 RPGWLPVSESVTRSTFKFTRLIEGNEYVFRVAATNRFGIGSYLQSEVIECRSSINI 29948
Score = 51.6 bits (122), Expect = 3e-06
Identities = 34/110 (30%), Positives = EVSDPQAC-VVWRKDDVELGPSDKYDFLHTAGTRGLVVHDLS 1063
Query: 747 KGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA-G 923
+ DTG YTC VG + AQ+ + + + TK+L +TVE EG S E ++
Sbjct: 1064 RDDTGLYTC----SVGLEETRAQVIVHD--LHVGITKRL-KTVEVLEGQSCSFECVLSHE 1116
Query: 924 SQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTS 1103
S + W + + T + L V+ A+ DAG + + A
Sbjct: 1117 STGDAATWTVGGKMVGDSGRFRATRQGRKYTLAVRDAAASDAGEVVFSMRDLTSKA---- 1172
Query: 1104 SIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHV-RGSEPIRIQWLKAGREIKPSDRCSF 1280
S++++E +P + L + G+ + LSC + R S P+R WL+ G+ I+ S +
Sbjct: 1173 SLIVRE--RPVDITKPLEDQRAAPGDDVVLSCELSRASTPVR--WLRDGKSIRNSQKYEL 1228
Query: 1281 SFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKL 1460
A+L V+ D+G Y C+ ++ SK+ T
Sbjct: 1229 VTEGTRAMLVVHAVSLRDSGQYSCE------TEASKTTATVCVEEKANR----------- 1271
Query: 1461 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEI 1640
F+ E ++V EK TA F+ K P V W KG +L+ + Q+G KL I
Sbjct: 1272 -FMEELADVQVEEKGTAVFMCKT-EHPAAMVTWRKGV-TELHASRKHVPSQEGLTLKLTI 1328
Query: 1641 RDTTKTDSGLYRC 1679
K DS Y C
Sbjct: 1329 NALEKADSDTYTC 1341
Score = 127 bits (318), Expect = 5e-29
Identities = 139/610 (22%), Positives = 233/610 (38%), Gaps = 7/610 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VT G+ +L C++ T + V W K LRP+A ++ + A L+ D G Y
Sbjct: 1520 VTEGEELTLVCEIT-TLDGSVCWTKDGKVLRPSARCQLSQEGHRAQLIITGATMQDGGRY 1578
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A G+ SS+ + V + P F L+D+ G C +S + V W
Sbjct: 1579 KCEA----GDSWSSSIVRVHAR--PVCFREGLQDLDVLEGSAATLRCVLS-TVAAPVQWR 1631
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
+ L+ G V L + +GQYSC + + A+ + + TE
Sbjct: 1632 RGDEVLRPGGKYSMRQDGPVLELVVRDLRPQDSGQYSCCFGDKMTLATLNVKAQPTE--- 1688
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
F L +A G +A C ++ P++ W K +R+G + L
Sbjct: 1689 ---FIGRLRNKEATEGATATLRCELSKAAPVE--WRKGPEALRAGDRVSLRQDGAVCELQ 1743
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
I + D+G+Y+C G++ A L ++E +P FTK L E +EG + L
Sbjct: 1744 IRGLAVEDSGEYSCVC----GQERTAAVLTVRE--LPTKFTKSL-RNEEASEGATATLRC 1796
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
++ + P V W K + + LQ++ ++ D+G Y+C + +A
Sbjct: 1797 ELSKAAP--VEWRKGPEALRAGDRVSLRQDGAVCELQIRGLAVEDSGEYSCVCGQERTAA 1854
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
+ T + P F + L +EG L C + + P ++W K ++ DR
Sbjct: 1855 VLTVRAL------PAKFTKGLRKEEATEGATATLRCELSKAAP--VEWRKGPEALRAGDR 1906
Query: 1272 CSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVD 1451
S L+ + + D+G+Y C V G + + + +T
Sbjct: 1907 VSLRQDGAVCELQIRGLAVEDSGEYSC----VCGQERTAAVLTVRALPAK---------- 1952
Query: 1452 GKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAK 1631
F + E TAT ++ V+W KG L G R+ + Q G +
Sbjct: 1953 ----FTKGLRKEEATEGATATLRCEL--SKAAPVEWRKGP-EALRAGDRVSLRQDGAVCE 2005
Query: 1632 LEIRDTTKTDSGLYRCVAFNKH-------GEIESNVNLQVNERKKQEKIEGDLRAMLKKT 1790
L+IR DSG Y CV + E+ + + + E LR L K
Sbjct: 2006 LQIRGLAVEDSGEYSCVCGQERTAAVLTVRELPTKFTKSLRNEEASEGATATLRCELSKA 2065
Query: 1791 PVLKKGAGEE 1820
++ G E
Sbjct: 2066 APVEWRKGPE 2075
Score = 120 bits (300), Expect = 6e-27
Identities = 135/569 (23%), Positives = 222/569 (39%), Gaps = 6/569 (1%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+V G +A L+C+L+ V W KG +L P A Y+M + L+ + D+G
Sbjct: 2226 EVDEGATACLRC50/110 (45%)
Frame = +3
Query: 846 SFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQV 1025
S K +T+ G +FRLE V G ++ W + + EI +A EI + LL V
Sbjct: 23643 SMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARYEIKNTDFKALLIV 23702
Query: 1026 KKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSE 1175
K A D G Y + SN AGS ++ + + PP +T VT +
Sbjct: 23703 KDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTAEK 23752
Score = 50.8 bits (120), Expect = 4e-06
Identities = 82/374 (21%), Positives = 132/374 (35%), Gaps = 41/374 (10%)
Frame = +3
Query: 138 NVAT---LVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV 308
NV T L+ D G Y+ A NS G F+ +V +
Sbjct: 15171 NVGTKSELIIKNALRKDHGRYVITATNSCGS----------------KFAAARVEVFDVP 15214
Query: 309 GLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNI------FQTDRSFA 470
G + + V+ + ++W P DG + T F+ + +T+RS
Sbjct: 15215 GPVLDLKPVVTNRKMCLLNW---SDPEDDGGSEITGFIIERKDAKMHTWRQPIETERS-- 15269
Query: 471 GQYSCTATNPIGSASSSARLILTE--GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPI 644
C T + R+I G PP P+ VD + G E +T T+
Sbjct: 15270 ---KCDITGLLEGQEYMFRVIAKNKFGCGPPVEIGPILAVDPL-GPPTSPE-RLTYTERT 15324
Query: 645 KVAWAKDNREIRSGGNYQIS--YLENSAH-----------------LTILKVDKGDTGQY 767
K D +E RS G I +E H + +D+ ++
Sbjct: 15325 KSTITLDWKEPRSNGGCPIQGYIIEKRRHDKPDFERVNKHLCPTTSFLVEDLDEHQMYEF 15384
Query: 768 TCYAVNEVGKDSCTAQLN--IKERLIPPSFTKKLS---ETVEETEGNSFRLEGRVAGSQP 932
AVNE+G+ + LN I++ +PP+ +LS +T++ G + V G
Sbjct: 15385 RVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVNIPADVTGLPM 15444
Query: 933 ISVAWYKNNVEIHPTANC------EITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSAL 1094
+ W KN I + E++ L + KA+ D G YT SN GS
Sbjct: 15445 PKIEWSKNETVIEKPTDALKITKEEVSRSEAKTELSIPKATREDKGTYTVTASNRLGSVF 15504
Query: 1095 CTSSIVIKEPKKPP 1136
+ + + PP
Sbjct: 15505 RNVHVEVYDRPSPP 15518
Score = 50.8 bits (120), Expect = 4e-06
Identities = 75/378 (19%), Positives = 128/378 (33%), Gaps = 31/378 (8%)
Frame = +3
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
G P +V+W KD + L D+ + L I Q R G+Y T N +G SS
Sbjct: 27314 GRPPPTVTWRKDEKNLGSDARYSIQNTDSSSILTIPQVTRHDTGKYILTIENGVGQPKSS 27373
Query: 522 ARLI----------------LTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVA 653
+ +++G F+D PL + G PI +
Sbjct: 27374 TVSVKVLDTPAACQNLQVKHVSQGTVTLFWDPPL----------------IDGGSPI-IN 27416
Query: 654 WAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVG-KDSCTAQLNIKE 830
+ + ++ +S+ +S + + + + +AVNE+G + C +K
Sbjct: 27417 YIIEKKDATKRTWSSVSHKCSSTSFKVTDLSEKTPFFFRVFAVNEIGIGEPCETTEPVKA 27476
Query: 831 RLIPPSF-----------TKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPT 977
+P + LS T + +G S + V W ++ I T
Sbjct: 27477 AEVPAPIRDLSVKDSTKTSVTLSWTKPDFDGGSVITDYIVERKGKGEQTW--SHAGISKT 27534
Query: 978 ANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT 1157
E+ L+ + ++ + GL ++ + +KE PP D
Sbjct: 27535 CEIEVGKLKELSELEFRVSARNEKGL---------SDSVSIGPVTVKELVIPPEVDLSEI 27585
Query: 1158 P---VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTK 1328
P V V G + L +G I WLK G +K S+ L K+ K
Sbjct: 27586 PGAQVAVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESELVRLGKTENKLTLSIKNAKK 27645
Query: 1329 ADAGDYVCKASNVAGSDT 1382
+ G Y N +T
Sbjct: 27646 ENGGKYTIILDNAVCRNT 27663
>ref|NP_001179466.1| hemicentin-1 [Bos taurus].
Length = 5635
Score = 191 bits (486), Expect = 2e-48
Identities = 152/581 (26%), Positives = 248/581 (42%), Gaps = 5/581 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 18ELSQECA-SVDWRKGSLQLFPCAKYQMVQKGTTVELLVRSAEQEDAGH 2284
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEP-ISVS 365
Y C G S+ L+V+ + P F +L+ ++ G C +S +E + V
Sbjct: 2285 YTC----DTGHTQSTASLSVRACR--PVFQEELQSTEQEAGGVAWLHCQLSKAETDVPVQ 2338
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W K+G L P + + L I + G+Y C A G + A +++ E
Sbjct: 2339 WLKEGVELHLSPKYEIRRVGTTCELLIHGLEPKDTGEYVCVA----GGQKTMASVMVKE- 2393
Query: 546 RNPPFFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
P I VDA V D F C V+ V W ++S ++S
Sbjct: 2394 ---PEVTIVRGLVDAEVQVDGDVEFSCEVSRAGVTNVEWRLQGLPLQSNEVTEVSVRGGR 2450
Query: 720 AHLTILK-VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
H+ LK V D G + + VG + +AQL ++ +P + + V+ +EG
Sbjct: 2451 THMLQLKGVTPEDAGTVSFH----VGMHTSSAQLTVR---VPEVTIVEALQDVQLSEGQD 2503
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNAL-LLQVKKASMGDAGLYTCKVS 1073
+++ + W V + +IT ++ L LL + K ++ DAG + +V
Sbjct: 2504 AHFRCQLSRASGQEAHWALGGVPLKANEMNDITVEHGTLHLLTLHKVTLEDAGTISFQVG 2563
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
+ C+S +K + P + L V V GE SC V + +W G
Sbjct: 2564 S------CSSEAQLKVTEAAPCLVRGLQNVDVFAGEVATFSCEVSRAGGPEARWWLDGTL 2617
Query: 1254 IKPSDRCSFSFANGTA-VLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
++ + + S +GT L + AD+G +A + T+K V
Sbjct: 2618 LQDGPQSAISVRDGTFHSLTLSGLGVADSGTITYRAGPLVS--TAKLLVK---------- 2665
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
D + VS Q + V E A + + P+ W + G R+ I
Sbjct: 2666 ------DPTVEVVSAMQDLVVEEGGPAELLCQYSR-PV-QATWKMDEQEVRADGRRVVIE 2717
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKH 1697
Q A+L R DSG+Y C A H
Sbjct: 2718 QDWTVARLSFRPALPCDSGIYSCEAAGTH 2746
Score = 116 bits (291), Expect = 7e-26
Identities = 157/666 (23%), Positives = 252/666 (37%), Gaps = 61/666 (9%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAG-TPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
V+V G S S +C L+ + +W G + + ++ + TL ++D+
Sbjct: 1099 VEVLEGQSCSFECVLSHESTGDAATWTVGGKMVGDSGRFRATRQGRKYTLAVRDAAASDA 1158
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GE + S+ +++S L V+E+ P ++ L D + G VV C +S + V
Sbjct: 1159 GEVVF----SMRDLTSKASLIVRER--PVDITKPLEDQRAAPGDDVVLSCELSRAST-PV 1211
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W +DG+ +++ + A L + +GQYSC AS + + E
Sbjct: 1212 RWLRDGKSIRNSQKYELVTEGTRAMLVVHAVSLRDSGQYSCET-----EASKTTATVCVE 1266
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ F + LA V +A F C T V W K E+ + + S +
Sbjct: 1267 EKANRFME-ELADVQVEEKGTAVFMCK-TEHPAAMVTWRKGVTELHASRKHVPSQEGLTL 1324
Query: 723 HLTILKVDKG-------DTGQYTCYA-------------------------------VNE 788
LTI ++K D GQ + A
Sbjct: 1325 KLTINALEKADSDTYTCDIGQASSQARLLVQAFEFDFSEGKTVVTLLVLLFIPDLMVSGT 1384
Query: 789 VGKDS--CTAQLNIKERLIP--------PSFTKKLS----ETVEETEGNSFRLEGRVAGS 926
+G D+ C Q + + P P + L E VE EG S R++ +
Sbjct: 1385 LGMDAGGCGVQFSSRGPSAPSLCAPQEDPGGQRVLITEALEDVEVREGASATFSCRISPA 1444
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNAL-LLQVKKASMGDAGLYTCKVSNDAGSALCTS 1103
V W+ + +HP EI + +L +++ ++ D+G + + SA
Sbjct: 1445 DYGPVHWFLDKTPLHPNELNEIEVQPGGYHVLTLRQLALKDSGTIHFEAGDQRASA---- 1500
Query: 1104 SIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFS 1283
++ +KP VF + LT TV+EGE L L C + + + W K G+ ++PS RC S
Sbjct: 1501 --TLRVTEKPSVFSRELTDTTVTEGEELTLVCEITTLDG-SVCWTKDGKVLRPSARCQLS 1557
Query: 1284 FANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLF 1463
A L 5
V V G S SL+C P ++WYK L +A ++ + L + + +D+G
Sbjct: 3069 VNVREGTSVSLECGSNAVPPPVITWYKNGRMLTESA--RLEILADGQMLHITKAEVSDTG 3126
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQ-ETVGLPVVFECAVSGSEPISV 362
+Y+CRA N G + L V +PPS +V ETV PV C +G P S+
Sbjct: 3127 QYVCRAINVAGRDDKNFHLNVY---VPPSIEGPENEVTVETVSNPVTLTCDATGIPPPSI 3183
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+ RP+++ +++ L L I ++ S +G Y+C A+N G A L +
Sbjct: 3184 AWLKNHRPIENSGSLEVHILSGGRKLQIARSQHSDSGNYTCIASNMEGKAQKHYILSIQV 3243
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
N +IP + V ++GE+ + C G + W KD + I S +I + +
Sbjct: 3244 PPNVADAEIP-SEVSVLLGENVELVCSANGIPTPLIQWLKDGKPIVSSETERIRVAADGS 3302
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF--TKKLSETVEETEGNS 896
L I D G+YTC A N G++ LN+ +PP+ K+ +E + S
Sbjct: 3303 TLNIYGALPSDMGKYTCVATNPAGEEDRIFNLNV---YVPPAIRGNKEEAEKLMALVDTS 3359
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
+E R G P + W KN + + + I + ++++ +A D +YTC SN
Sbjct: 3360 INIECRATGMPPPQINWLKNGLPL--PLSSHIRLLSGGQVIRIVRAQASDVAVYTCVASN 3417
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHL--TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
AG S+ + PP D + +T+ +G ++C G+ R+ WL+ GR
Sbjct: 3418 RAGVDNKHFSLQV---LVPPSLDNGMGTEEITIVKGSSTSMTCFTDGTPAPRMSWLRDGR 3474
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
+ S S + VL+ D+G Y C ASN AG + SK +
Sbjct: 3475 PLGLDAHLSIS--SQGMVLQLIKAETEDSGRYTCIASNEAG-EVSKHFI--------LKI 3523
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
++G EP + V+ G P P + W K R L Q + +
Sbjct: 3524 LEPPHINGS----EEPMEMSVIVNNPLELTCMASGIPAPKITWMK-DGRPLPQMDQ--MQ 3576
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
G L I T D+G Y C+A + G+ + ++V+
Sbjct: 3577 TLGGGEVLRISSTQVEDTGRYTCLASSPAGDDDKEYLVRVH 3617
Score = 183 bits (465), Expect = 4e-46
Identities = 155/595 (26%), Positives = 241/595 (40%), Gaps = 22/595 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V V L+C+ AGTP ++WYK + L +++ R + + Q+ D+G Y
Sbjct: 1932 VVVNSPVQLECKAAGTPSPAITWYKDNRPLSDSSSVTFLNRGQIINIESAQI--TDAGIY 1989
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A NS G ++ F ++Q +PPS V V V EC G S++W
Sbjct: 1990 KCVAINSAG--ATELFYSLQVH-VPPSIFGSNNMVAVVVNNLVRLECEARGIPAPSLTWL 2046
Query: 372 KDGRPLKDGPNIQTSFLDNVATLN------IFQTDRSFAGQYSCTATNPIGSASSSARL- 530
KDG P+ TSF++ + L+ + S G+Y+C A N G L
Sbjct: 2047 KDGSPV-------TSFVNGIQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLR 2099
Query: 531 ------ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
I+ E +N V ++ ++ + C P + W KD +
Sbjct: 2100 VYVAPNIMGEEQN----------VSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPG 2149
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET 872
+S EN + L I D+G+YTC A N GK +NI +PP+ + E
Sbjct: 2150 --LSVTENGSVLKIEDAQVQDSGRYTCEATNVAGKTEKNYNVNI---WVPPNISGS-DEA 2203
Query: 873 VEET--EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGD 1046
+ T EG+ L +G P ++ W K + + + + LQ+ A D
Sbjct: 2204 AQLTVIEGHLISLLCESSGIPPPNLIWKKKGSPVLADSAGRVRILSGGRQLQISVAEKSD 2263
Query: 1047 AGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIR 1226
AGLY+C SN AG+A S+ + H T + V+ G+ + L C V G
Sbjct: 2264 AGLYSCMASNVAGTAKKDYSLQVYIRPTISNSGSHPTEIIVTRGKSVSLECEVEGVPQPA 2323
Query: 1227 IQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXX 1406
+ W+K GR + + V++ K+V +D G YVC A N+AG K ++
Sbjct: 2324 VTWMKDGRPLTKGR--GMEIMDEGRVVQLKNVHVT D G Y C+ AG S S V +
Sbjct: 1558 QEGHRAQLIITGATMQDGGRYKCE----AGDSWSSSIVRVHAR--------------PVC 1599
Query: 1464 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIR 1643
F Q + V+E + AT + P V+W +G L GG+ + Q G +L +R
Sbjct: 1600 FREGLQDLDVLEGSAATLRCVLSTVAAP-VQWRRGD-EVLRPGGKYSMRQDGPVLELVVR 1657
Query: 1644 DTTKTDSGLYRCVAFNKHGEIESNVNLQ----VNERKKQEKIEG---DLRAMLKKTPVLK 1802
D DSG Y C +K NV Q + + +E EG LR L K ++
Sbjct: 1658 DLRPQDSGQYSCCFGDKMTLATLNVKAQPTEFIGRLRNKEATEGATATLRCELSKAAPVE 1717
Query: 1803 KGAGEE 1820
G E
Sbjct: 1718 WRKGPE 1723
Score = 102 bits (254), Expect = 1e-21
Identities = 135/559 (24%), Positives = 220/559 (39%), Gaps = 2/559 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ T D +L+C+L+ P + V W K +LR T M + +L+ + + D G
Sbjct: 475 IVATEKDKVTLECELS-RPNVDVRWLKDGVELRVGKTVGMVAQGACRSLIIYRCELGDQG 533
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y+C A + SS L VQ +K+ R L DV+ F C VS E +
Sbjct: 534 VYVCDAH----DTQSSASLKVQGRKV--QIVRPLEDVEVMEKEGATFSCEVSLDE-VPAE 586
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WF +G L+ N++ TL + AG+ + +A S A+L + E
Sbjct: 587 WFWEGSKLRPSDNVRIRQEGRTHTLIYRRVLVEDAGEIKFV----VETAESRAQLRVKE- 641
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P PL A+ EC ++ +V W K + E+ SG Y++
Sbjct: 642 -LPVTILRPLRDKIAMEKHRGVLECQMSRAS-AQVQWFKGSVELHSGPKYEMVSDGLYRK 699
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSE-TVEETEGNSFR 902
L I V D YTC + G +AQ ++E+ I + + L + TV E F
Sbjct: 700 LVIKDVQPEDEDTYTC----DAGDVKTSAQFFVEEQSI--TIVRGLQDMTVMEPAPAWFE 753
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
E + +P W + AN + + L +++ T V
Sbjct: 754 CETSIPSVRP--PKWLLGKTVLQAGANVGMEQEGTVHRLTLRRT----CSTMTGPVHFTI 807
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G + T+ +V+ + P V + L P E + + LSC + P +QW K + P
Sbjct: 808 GKSRSTARLVVSD--IPMVLTRPLEPKAGRELQSVVLSCDFK-PPPKAVQWYKEDTPLAP 864
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S++ A L +T ADAG Y C+ AGS S ++VT
Sbjct: 865 SEKFKMMLEGHMAELRILRLTPADAGIYRCQ----AGSAQSSAQVT-------------- 906
Query: 1443 XVDGKLFFVSEP-QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V+ + V++P Q +V E+ A F ++ + V+W+ N H+ G
Sbjct: 907 -VEAREVTVTQPLQDAQVTEEGRACFSCELSHED-EEVEWSLNGAPLYNDSFHEITHE-G 963
Query: 1620 DEAKLEIRDTTKTDSGLYR 1676
L ++ + D+G R
Sbjct: 964 RCHTLVLKRVRRVDTGTVR 982
Score = 102 bits (254), Expect = 1e-21
Identities = 114/466 (24%), Positives = 178/466 (38%)
Frame = +3
Query: 285 LRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRS 464
L DV+ G F C +S ++ V WF D PL PN ++ T R
Sbjct: 1424 LEDVEVREGASATFSCRISPADYGPVHWFLDKTPLH--PNELNEIEVQPGGYHVL-TLRQ 1480
Query: 465 FAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPI 644
A + S T G +SA L +TE P F L GE C +T T
Sbjct: 1481 LALKDSGTIHFEAGDQRASATLRVTE--KPSVFSRELTDTTVTEGEELTLVCEIT-TLDG 1537
Query: 645 KVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI 824
V W KD + +R Q+S + A L I D G+Y C E G ++ + +
Sbjct: 1538 SVCWTKDGKVLRPSARCQLSQEGHRAQLIITGATMQDGGRYKC----EAGDSWSSSIVRV 1593
Query: 825 KERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKN 1004
R P F + L + ++ EG++ L V + V W + + + P +
Sbjct: 1594 HAR--PVCFREGLQD-LDVLEGSAATLR-CVLSTVAAPVQWRRGDEVLRPGGKYSMRQDG 1649
Query: 1005 NALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEF 1184
L L V+ D+G Y+C G + SDTGRYVCVAMNIAGMTDRKYDLSVH 2381
Query: 1407 XXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKW---- 1574
P++I VVEK++ + + G P+P++ W K W
Sbjct: 2382 TPPSIIGNHRT------------PENISVVEKSSVSLNCEASGIPLPSITWLKDGWPVNL 2429
Query: 1575 ---RQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
++ GGRI L + T D+G Y CV N GE L V
Sbjct: 2430 SSSLRILSGGRI----------LRLMQTRTEDAGQYTCVVRNAAGEERKIFRLSV 2474
Score = 175 bits (443), Expect = 2e-43
Identities = 169/609 (27%), Positives = 261/609 (42%), Gaps = 14/609 (2%)
Frame = +3
Query: 3 PVKVTV--GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSN 176
PV+++V G+ +L C++ G P ++W K + P + + + +V +
Sbjct: 1086 PVEISVFAGEEVTLPCEVKGLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRV--S 1143
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
DSG Y+C A N G V+ S L V +PP R + ++ VG V C+ G+
Sbjct: 1144 DSGMYLCVATNIAGNVTQSVKLNVH---VPPKIQRGPKVMKVQVGQRVDIPCSAQGTPLP 1200
Query: 357 SVSWFKDGRP-LKDGPNIQTSFLDNV----ATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
++WFK G L DG L ++ TL+I Q S AG Y+C ATN GS +
Sbjct: 1201 VITWFKGGGAVLVDG-------LQHIRHPDGTLSIKQAVLSDAGIYTCVATNIAGSDETE 1253
Query: 522 ARLILTEGRNPPFFDIPLAPVDA-----VVGESADFECHVTGTQPIKVAWAKDNREIRSG 686
L + E PP + P + V + F C GT + W ++ RE+ +G
Sbjct: 1254 ITLHVQE---PPILEDLEPPYNTPFQERVANQRIAFPCPAKGTPKPTIKWLRNGREL-TG 1309
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLS 866
IS LE+ L I V D G+Y C AVNE G + + N+K + P K+
Sbjct: 1310 QEPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG--TTERRYNLKVHVPPVIKDKEQV 1367
Query: 867 ETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGD 1046
V L V G+ + WYK++V++ T + I NN +L++ + S D
Sbjct: 1368 TNVSVLVNQPTSLFCEVEGTPSPIIMWYKDDVQV--TESSSIQIVNNGKILKLFRTSPED 1425
Query: 1047 AGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP--VTVSEGEFLQLSCHVRGSEP 1220
AG Y+CK N AG++ +I + PP +P V+V + L C V+G+
Sbjct: 1426 AGGYSCKAVNVAGTSQKHFNI---DVLVPPTIIGAGSPGEVSVVLNQNTTLECQVKGTPF 1482
Query: 1221 IRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
I+WLK G+ + D + + VL K+ ++D G Y C SN AG K+T
Sbjct: 1483 PVIRWLKDGKPLFLGDP-NIEILDRGQVLHLKNARRSDKGRYQCSVSNAAGKQAKDIKLT 1541
Query: 1401 XXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQ 1580
V + SI +E T G P+P + W K
Sbjct: 1542 IYIPPSIKGGNVTTEVSALI------NSIIKLECETR-------GLPMPAITWYKDGQPV 1588
Query: 1581 LNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIE 1760
++ +++ +KG L I +DS Y+C+ N G E + ++ V IE
Sbjct: 1589 ISSSQALYV-EKGQ--FLHIPRAQVSDSAAYKCLVTNVAGTAEKSFHVDV---YVPPVIE 1642
Query: 1761 GDLRAMLKK 1787
GDL L K
Sbjct: 1643 GDLAEPLNK 1651
Score = 175 bits (443), Expect = 2e-43
Identities = 151/581 (25%), Positives = 239/581 (41%), Gaps = 8/581 (1%)
Frame = +3
Query: 15 TVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYI 194
TV + +L C G P ++W K + + + ++H + L + +DSG Y
Sbjct: 3164 TVSNPVTLTCDATGIPPPSIAWLKNHRPIENSGSLEVHILSGGRKLQIARSQHSDSGNYT 3223
Query: 195 CRAENSVGEVSSSTFLTVQEQKLPPSFSRQL--RDVQETVGLPVVFECAVSGSEPISVSW 368
C A N G+ L++Q +PP+ + +V +G V C+ +G + W
Sbjct: 3224 CIASNMEGKAQKHYILSIQ---VPPNVADAEIPSEVSVLLGENVELVCSANGIPTPLIQW 3280
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
KDG+P+ + + +TLNI+ S G+Y+C ATNP G R+
Sbjct: 3281 LKDGKPIVSSETERIRVAADGSTLNIYGALPSDMGKYTCVATNPAGEED---RIFNLNVY 3337
Query: 549 NPPFFDIPLAPVD---AVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
PP + A+V S + EC TG P ++ W K+ + + ++ L
Sbjct: 3338 VPPAIRGNKEEAEKLMALVDTSINIECRATGMPPPQINWLKNGLPLPLSSHIRL--LSGG 3395
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKL-SETVEETE +++ +K +P F L +EG
Sbjct: 1650 PVLELVVRDLRPQDSGQYSCCF----GDKMTLATLNVK--AQPTEFIGRLRNKEATEGAT 1703
Query: 1185 LQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASN 1364
L C + + P ++W K ++ DR S L+ + + D+G+Y C
Sbjct: 1704 ATLRCELSKAAP--VEWRKGPEALRAGDRVSLRQDGAVCELQIRGLAVEDSGEYSC---- 1757
Query: 1365 VAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPI 1544
V G + + + +T F ++ E TAT ++
Sbjct: 1758 VCGQERTAAVLTVRELPTK--------------FTKSLRNEEASEGATATLRCEL--SKA 1801
Query: 1545 PNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCV 1682
V+W KG L G R+ + Q G +L+IR DSG Y CV
Sbjct: 1802 APVEWRKGP-EALRAGDRVSLRQDGAVCELQIRGLAVEDSGEYSCV 1846
Score = 98.6 bits (244), Expect = 2e-20
Identities = 142/584 (24%), Positives = 223/584 (38%), Gaps = 3/584 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLA--GTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSND 179
V+ G SA+L C++A GT V+WYK KL ++ + + LV Q D
Sbjct: 29 VQAKAGGSATLSCEVAQAGTE---VTWYKDGKKLSASSRVHVEAQGCSRRLVVQQAGRAD 85
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
+GEY C A G S L V E + F + L +G V C +S +
Sbjct: 86 AGEYSCEA----GGQKVSFRLDVAE--VAAKFCQHLEPASGELGGTVTLACELSPPQ-AE 138
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V W L+ G + TL + AG+Y+C + +SA+L ++
Sbjct: 139 VVWRHGSAQLRAGKRFRMEAAGPRRTLTVSGLRLEDAGEYACETRDD----RTSAQLTVS 194
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
R F L+ A G A F+C V V+W +D ++ + IS S
Sbjct: 195 APRMVKFTS-GLSAAVAEEGSEATFQC-VVSPSDAAVSWFRDGALLQPSEKFLISQSGAS 252
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLS-ETVEETEGNS 896
LT+ + D+GQ T A + +A L ++E P F KKL +TVEE +
Sbjct: 253 HSLTVCSLTLEDSGQITVEAEGVLS----SAALRVRE--APVLFRKKLEPQTVEER--SL 304
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
+E + P V W +N + P N EI ++ + L ++ D G Y C+ +
Sbjct: 305 VTMEVELTRPWP-EVKWTRNATALAPGKNVEIHAESTSHRLILRCVGFADRGFYGCETPD 363
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
D A T + + + L V SE + + + + + W G +
Sbjct: 364 DKTQAKLTVEM------RQVRLVRGLQAVEASEQGTVSMEVEL-SHDDVEGSWTHDGLRL 416
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
+P C + L + D+G KA G TS V
Sbjct: 417 QPGPTCQLAVHGPIHTLTLFGLRPQDSGLIAFKAE---GVHTSARLVV------------ 461
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
+ + F Q I EK T ++ P +V+W K +L G + + +
Sbjct: 462 ---TELPVRFSRPLQDIVATEKDKVTLECEL-SRPNVDVRWLK-DGVELRVGKTVGMVAQ 516
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQ 1748
G L I D G+Y C A + +S+ +L+V RK Q
Sbjct: 517 GACRSLIIYRCELGDQGVYVCDAH----DTQSSASLKVQGRKVQ 556
Score = 89.4 bits (220), Expect = 1e-17
Identities = 85/331 (25%), Positives = 120/331 (36%), Gaps = 59/331 (17%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKM-HFRNNVATLVFNQVDSNDSG 185
+V G S C +AG P V W+K L Y + + L+ V D G
Sbjct: 3546 EVLDGYPVSFDCVVAGQPVPTVCWFKDGRMLEEDDHYMISEDQQGGHQLIITAVVPADMG 3605
Query: 186 EYICRAENSVGEVSSSTFLTVQ-------------------------------------E 254
Y C AENSVG S+ L V E
Sbjct: 3606 VYRCMAENSVGVSSTKAELRVDLTSTDYETAADATETSSYFSAQGYLSSREQEGTESTSE 3665
Query: 255 QKLPPSFSRQLRDVQETVGLPVV-FECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNV 431
+ P +L+D+Q G + F+ V G + WFKDG+PL +I + +
Sbjct: 3666 EGQLPQVVEELKDLQVAPGTRLAKFQVKVKGYPAPRLYWFKDGQPLTASEHIHMADRKTL 3725
Query: 432 ATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN--------------PPFFDI 569
TL + GQYS +N +G+A SSARLI+ ++ PP F
SbjctGNS 896
+ I++ D YTC A N G D+ L + L+PPS + +E + +G+S
Sbjct: 3396 QVIRIVRAQASDVAVYTCVASNRAGVDNKHFSLQV---LVPPSLDNGMGTEEITIVKGSS 3452
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
+ G+ ++W ++ + A+ I+ + ++LQ+ KA D+G YTC SN
Sbjct: 3453 TSMTCFTDGTPAPRMSWLRDGRPLGLDAHLSIS--SQGMVLQLIKAETEDSGRYTCIASN 3510
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSE--GEFLQLSCHVRGSEPIRIQWLKAGR 1250
+AG S I + +PP + P+ +S L+L+C G +I W+K GR
Sbjct: 3511 EAGEV---SKHFILKILEPPHINGSEEPMEMSVIVNNPLELTCMASGIPAPKITWMKDGR 3567
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
+ D+ G VL D G Y C AS+ AG D + V
Sbjct: 3568 PLPQMDQ--MQTLGGGEVLRISSTQVEDTGRYTCLASSPAGDDDKEYLVRVH-------- 3617
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
V + EPQ V+ T K P P + W K R L RI I
Sbjct: 3618 -----VPPNIAGTGEPQDFTVLRNRQVTLECKSDAVPPPVITWLKNGER-LQATPRIRIL 3671
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
G L+I + D+ Y CVA N G+ L VN
Sbjct: 3672 SGG--RYLQINNADLGDTANYTCVASNIAGKTTREFILTVN 3710
Score = 174 bits (440), Expect = 3e-43
Identities = 152/569 (26%), Positives = 234/569 (41%), Gaps = 2/569 (0%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENS 212
+LQC G P ++W K + TA + +++ L + D+G Y C A N+
Sbjct: 1845 TLQCIANGIPNPSITWLKDGQPVN-TAQGNLKIQSSGRLLQIAKALMEDAGRYTCVATNA 1903
Query: 213 VGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGL--PVVFECAVSGSEPISVSWFKDGRP 386
GE L V E PPS + + ETV + PV EC +G+ +++W+KD RP
Sbjct: 1904 AGETQQHIQLHVHE---PPSLDDAGKMLNETVVVNSPVQLECKAAGTPSPAITWYKDNRP 1960
Query: 387 LKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFD 566
L D ++ +FL+ +NI + AG Y C A N SA ++ + PP
Sbjct: 1961 LSDSSSV--TFLNRGQIINIESAQITDAGIYKCVAIN---SAGATELFYSLQVHVPPSIF 2015
Query: 567 IPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVD 746
V VV EC G + W KD + S N I L L +
Sbjct: 2016 GSNNMVAVVVNNLVRLECEARGIPAPSLTWLKDGSPVTSFVN-GIQVLSGGRILALTSAQ 2074
Query: 747 KGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGS 926
DTG+YTC AVN G+ L + + P+ + + V + L +
Sbjct: 2075 ISDTGRYTCVAVNAAGEKQRDIDLRV---YVAPNIMGE-EQNVSVLISQAVELLCQSDAI 2130
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS 1106
P ++ W K+ + +T N +L+++ A + D+G YTC+ +N AG +
Sbjct: 2131 PPPTLTWLKDGHPLLKKPGLSVT--ENGSVLKIEDAQVQDSGRYTCEATNVAGKTEKNYN 2188
Query: 1107 IVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSF 1286
+ I P D+ +TV EG + L C G P + W K G +
Sbjct: 2189 VNIWVPPNISGSDE-AAQLTVIEGHLISLLCESSGIPPPNLIWKKKGSPVLADSAGRVRI 2247
Query: 1287 ANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFF 1466
+G L+ K+DAG Y C ASNVAG T+K +
Sbjct: 2248 LSGGRQLQISVAEKSDAGLYSCMASNVAG--TAKKDYSLQVYIRPTISNSG--------- 2296
Query: 1467 VSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRD 1646
S P I V + + +V G P P V W K R L +G + I +G +++++
Sbjct: 2297 -SHPTEIIVTRGKSVSLECEVEGVPQPAVTWMK-DGRPLTKGRGMEIMDEG--RVVQLKN 2352
Query: 1647 TTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
+D+G Y CVA N G + +L V+
Sbjct: 2353 VHVSDTGRYVCVAMNIAGMTDRKYDLSVH 2381
Score = 166 bits (420), Expect = 7e-41
Identities = 147/581 (25%), Positives = 229/581 (39%), Gaps = 6/581 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V V + SL C+++G P +SW K + ++P + ++ +V +D GEY
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKPNTNALIVPGGRTLQIIRAKV--SDGGEY 3033
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSF----SRQLRDVQETVGLPVVFECAVSGSEPIS 359
C A N GE LTV +PPS S L V G V EC + P
Sb: 3726 HTLEVVSVTCEDDGQYSAYISNAVGAAYSSARLIVRGPKDPEEKPASDVQQQLVPPRFLE 3785
Query: 570 PLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI------RSGGNYQISYLENSAHLT 731
G S F V G V W ++ E R Y ++ L
Sbjct: 3786 RFTSKKVKKGSSITFSVKVEGFPAPAVHWLREEAERGVLWIGRDTPGYTVASSAQQHSLV 3845
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI 824
+L V + G YTC A N G+ C+A L++
Sbjct: 3846 LLDVGRPHQGTYTCIATNAAGQALCSASLHV 3876
Score = 89.0 bits (219), Expect = 2e-17
Identities = 112/485 (23%), Positives = 200/485 (41%), Gaps = 3/485 (0%)
Frame = +3
Query: 291 DVQETVGLPVVFECAVS--GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRS 464
+VQ G C V+ G+E V+W+KDG+ L + L + Q R+
Sbjct: 28 EVQAKAGGSATLSCEVAQAGTE---VTWYKDGKKLSASSRVHVEAQGCSRRLVVQQAGRA 84
Query: 465 FAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPI 644
AG+YSC A G S RL + E F L P +G + C ++ Q
Sbjct: 85 DAGEYSCEA----GGQKVSFRLDVAEVAAK--FCQHLEPASGELGGTVTLACELSPPQ-A 137
Query: 645 KVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI 824
+V W + ++R+G +++ LT+ + D G+Y C E D +AQL +
Sbjct: 138 EVVWRHGSAQLRAGKRFRMEAAGPRRTLTVSGLRLEDAGEYAC----ETRDDRTSAQLTV 193
Query: 825 K-ERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFK 1001
R++ FT LS V E EG+ + V+ S +V+W+++ + P+ I+
Sbjct: 194 SAPRMV--KFTSGLSAAVAE-EGSEATFQCVVSPSD-AAVSWFRDGALLQPSEKFLISQS 249
Query: 1002 NNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGE 1181
+ L V ++ D+G +++ +A L ++++ ++E P +F + L P TV E
Sbjct: 250 GASHSLTVCSLTLEDSG----QITVEAEGVLSSAALRVRE--APVLFRKKLEPQTVEERS 303
Query: 1182 FLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKAS 1361
+ + + P ++W + + P + + L + V AD G Y C+
Sbjct: 304 LVTMEVELTRPWP-EVKWTRNATALAPGKNVEIHAESTSHRLILRCVGFADRGFYGCETP 362
Query: 1362 NVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDP 1541
+ D +++K+T ++ V Q++ E+ T + ++ D
Sbjct: 363 D----DKTQAKLTVEMR--------------QVRLVRGLQAVEASEQGTVSMEVELSHDD 404
Query: 1542 IPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVN 1721
+ WT R L G + G L + DSGL +AF G + ++
Sbjct: 405 VEG-SWTHDGLR-LQPGPTCQLAVHGPIHTLTLFGLRPQDSGL---IAFKAEG-VHTSAR 458
Query: 1722 LQVNE 1736
L V E
Sbjct: 459 LVVTE 463
Score = 87.0 bits (214), Expect = 6e-17
Identities = 131/607 (21%), Positives = 222/607 (36%), Gaps = 56/607 (9%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENS 212
+LQC+++ P+ V W K D +L P+ Y LV + + +D+G Y C S
Sbjct: 1019 ALQCEVSD-PQACVVWRKDDVELGPSDKYDFLHTAGTRGLVVHDLSRDDTGLYTC----S 1073
Query: 213 VGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSG-SEPISVSWFKDGRPL 389
VG + + V + L +++L+ V+ G FEC +S S + +W G+ +
Sbjct: 1074 VGLEETRAQVIVHD--LHVGITKRLKTVEVLEGQSCSFECVLSHESTGDAATWTVGGKMV 1131
Query: 390 KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDI 569
D + + TL + S AG+ + + +S A LI+ E P
Sbjct: 1132 GDSGRFRATRQGRKYTLAVRDAAASDAGEVVFSMRD----LTSKASLIVRE--RPVDITK 1185
Query: 570 PLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDK 749
PL A G+ C ++ V W +D + IR+ Y++ A L + V
Sbjct: 1186 PLEDQRAAPGDDVVLSCELSRAST-PVRWLRDGKSIRNSQKYELVTEGTRAMLVVHAVSL 1244
Query: 750 GDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQ 929
D+GQY+C E TA + ++E+ F ++L++ E +G + +
Sbjct: 1245 RDSGQYSC----ETEASKTTATVCVEEKA--NRFMEELADVQVEEKGTAVFM---CKTEH 1295
Query: 930 PIS-VAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN---------- 1076
P + V W K E+H + + + L L + D+ YTC +
Sbjct: 1296 PAAMVTWRKGVTELHASRKHVPSQEGLTLKLTINALEKADSDTYTCDIGQASSQARLLVQ 1355
Query: 1077 --------------------------------DAG------SALCTSSIVIKEPKKPP-- 1136
Djct: 3034 TCVAINQAGESKKKVSLTVY---VPPSIKDHGSESLSVVNVREGTSVSLECGSNAVPPPV 3090
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W+K+GR L + ++ L + L+I + + S GQY C A N G + L +
Sbjct: 3091 ITWYKNGRMLTESARLE--ILADGQMLHITKAEVSDTGQYVCRAINVAGRDDKNFHLNVY 3148
Query: 540 EGRNPPFFDIPLAPVDA-VVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
PP + P V V C TG P +AW K++R I + G+ ++ L
Sbjct: 3149 V---PPSIEGPENEVTVETVSNPVTLTCDATGIPPPSIAWLKNHRPIENSGSLEVHILSG 3205
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK-KLSETVEETEGN 893
L I + D+G YTC A N GK L+I+ +PP+ ++ V G
Sbjct: 3206 GRKLQIARSQHSDSGNYTCIASNMEGKAQKHYILSIQ---VPPNVADAEIPSEVSVLLGE 3262
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
+ L G + W K+ I + I + L + A D G YTC +
Sbjct: 3263 NVELVCSANGIPTPLIQWLKDGKPIVSSETERIRVAADGSTLNIYGALPSDMGKYTCVAT 3322
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
N AG ++ + P + + + + C G P +I WLK G
Sbjct: 3323 NPAGEEDRIFNLNVYVPPAIRGNKEEAEKLMALVDTSINIECRATGMPPPQINWLKNGLP 3382
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
+ S +G V+ +D Y C ASN AG D +
Sbjct: 3383 LPLSSH--IRLLSGGQVIRIVRAQASDVAVYTCVASNRAGVDNKHFSLQVL--------- 3431
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
V L + I +V+ ++ + G P P + W + R L + I
Sbjct: 3432 ----VPPSLDNGMGTEEITIVKGSSTSMTCFTDGTPAPRMSWLRDG-RPLGLDAHLSISS 3486
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+G +L +T DSG Y C+A N+ GE+ + L++ E
Sbjct: 3487 QGMVLQLIKAETE--DSGRYTCIASNEAGEVSKHFILKILE 3525
Score = 162 bits (410), Expect = 1e-39
Identities = 158/609 (25%), Positives = 238/609 (39%), Gaps = 11/609 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V V SL C++ GTP + WYK D ++ T + + NN L + D+G
Sbjct: 1370 VSVLVNQPTSLFCEVEGTPSPIIMWYKDDVQV--TESSSIQIVNNGKILKLFRTSPEDAG 1427
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C+A N G + V +PP+ + +V + EC V G+
Sbjct: 1428 GYSCKAVNVAGTSQKHFNIDVL---VPPTIIGAGSPGEVSVVLNQNTTLECQVKGTPFPV 1484
Query: 360 VSWFKDGRPLKDG-PNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
+ W KDG+PL G PNI+ LD L++ RS G+Y C+ +N G + +L +
Sbjct: 1485 IRWLKDGKPLFLGDPNIE--ILDRGQVLHLKNARRSDKGRYQCSVSNAAGKQAKDIKLTI 1542
Query: 537 -----TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
+G N V A++ EC G + W KD + + S Q
Sbjct: 1543 YIPPSIKGGNVT------TEVSALINSIIKLECETRGLPMPAITWYKDGQPVISSS--QA 1594
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
Y+E L I + D+ Y C N G + +++ +PP L+E + +
Sbjct: 1595 LYVEKGQFLHIPRAQVSDSAAYKCLVTNVAGTAEKSFHVDV---YVPPVIEGDLAEPLNK 1651
Query: 882 TE--GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGL 1055
+S LE + AG+ P + W K+ V + + N I + L++ A D G
Sbjct: 1652 QVKVAHSLTLECKAAGNPPPVLTWLKDGVPVKASDNIRI--EAGGKKLEITSALEVDRGQ 1709
Query: 1056 YTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQW 1235
Y C ++ AG + + P D+ + V L+L C V GS I W
Sbjct: 1710 YICVATSVAGEKEIKYEVDVLVPPAIEGGDE-TSYFIVMVNNLLELDCQVTGSPLPTIMW 1768
Query: 1236 LKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXX 1415
LK G+ I +R F L +D G Y C A+N AG + +VT
Sbjct: 1769 LKDGQLI--DERDGFRILLNGHKLVIAQAQVSDTGLYRCVATNTAGDHRKEFEVTVHVPP 1826
Query: 1416 XXXXXXXXXXVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDPIPNVKWTKGKWRQLNQG 1592
S S R V K T G P P++ W K
Sbjct: 1827 TIK---------------SSGLSERAVLKYKPITLQCIANGIPNPSITWLKDGQPVNTAQ 1871
Query: 1593 GRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAAG S+ S+ + P++ P
Sbjct: 1356 AFEFDFSEGKTVVTLLVLLFIPDLMVSGTLGMDAGGCGVQFSSRGPSAPSLCAPQEDPGG 1415
Query: 1137 ---VFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSF-ANGTAV 1304
+ + L V V EG SC + ++ + W + P++ G V
Sbjct: 1416 QRVLITEALEDVEVREGASATFSCRISPADYGPVHWFLDKTPLHPNELNEIEVQPGGYHV 1475
Query: 1305 LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS 1484
L + + D+G +A + S T +VT +G+
Sbjct: 1476 LTLRQLALKDSGTIHFEAGDQRASAT--LRVTEKPSVFSRELTDTTVTEGE--------- 1524
Query: 1485 IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDS 1664
E T I + G +V WTK + L R + Q+G A+L I T D
Sbjct: 1525 ----ELTLVCEITTLDG----SVCWTK-DGKVLRPSARCQLSQEGHRAQLIITGATMQDG 1575
Query: 1665 GLYRCVA 1685
G Y+C A
Sbjct: 1576 GRYKCEA 1582
Score = 85.1 bits (209), Expect = 2e-16
Identities = 93/399 (23%), Positives = 159/399 (39%), Gaps = 66/399 (16%)
Frame = +3
Query: 267 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVA-TLN 443
P F +L++ + G PV F+C V+G +V WFKDGR L++ + S L
Sbjct: 3536 PVFLTELQNQEVLDGYPVSFDCVVAGQPVPTVCWFKDGRMLEEDDHYMISEDQQGGHQLI 3595
Query: 444 IFQTDRSFAGQYSCTATNPIGSASSSARLILT---------------------------- 539
I + G Y C A N +G +S+ A L +
Sbjct: 3596 ITAVVPADMGVYRCMAENSVGVSSTKAELRVDLTSTDYETAADATETSSYFSAQGYLSSR 3655
Query: 540 ----------EGRNPPFF----DIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI 677
EG+ P D+ +AP + A F+ V G ++ W KD + +
Sbjct: 3656 EQEGTESTSEEGQLPQVVEELKDLQVAPGTRL----AKFQVKVKGYPAPRLYWFKDGQPL 3711
Query: 678 RSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQL------------- 818
+ + ++ + L ++ V D GQY+ Y N VG +A+L
Sbjct: 3712 TASEHIHMADRKTLHTLEVVSVTCEDDGQYSAYISNAVGAAYSSARLIVRGPKDPEEKPA 3771
Query: 819 -NIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEI------HPT 977
+++++L+PP F ++ + + + +G+S +V G +V W + E T
Sbjct: 3772 SDVQQQLVPPRFLERFT-SKKVKKGSSITFSVKVEGFPAPAVHWLREEAERGVLWIGRDT 3830
Query: 978 ANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKE-PKKPPVFDQHL 1154
+ L + G YTC +N AG ALC++S+ + PK+ V ++H
Sbjct: 3831 PGYTVASSAQQHSLVLLDVGRPHQGTYTCIATNAAGQALCSASLHVSGLPKETRVAEEHA 3890
Query: 1155 TPVTVSEGEFLQ--LSCHVRGSEPIRIQWLKAGREIKPS 1265
FLQ + + SEP+ L AG+ +P+
Sbjct: 3891 GVKEALISTFLQGTQAISTQMSEPVGFADL-AGQRKEPT 3928
Score = 80.9 bits (198), Expect = 4e-15
Identities = 95/427 (22%), Positives = 174/427 (40%), Gaps = 6/427 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLV-FNQVDSNDS 182
V+++ G A +CQL+ W G L+ + + L+ ++V D+
Sbjct: 2496 VQLSEGQDAHFRCQLSRASGQEAHWALGGVPLKANEMNDITVEHGTLHLLTLHKVTLEDA 2555
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G + VG SS L V E P R L++V G F C VS +
Sbjct: 2556 GTISFQ----VGSCSSEAQLKVTEAA--PCLVRGLQNVDVFAGEVATFSCEVSRAGGPEA 2609
Query: 363 SWFKDGRPLKDGPNIQTSFLDNV-ATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
W+ DG L+DGP S D +L + + +G T T G S+A+L++
Sbjct: 2610 RWWLDGTLLQDGPQSAISVRDGTFHSLTLSGLGVADSG----TITYRAGPLVSTAKLLVK 2665
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE-N 716
+ P ++ A D VV E E ++P++ W D +E+R+ G + +
Sbjct: 2666 D----PTVEVVSAMQDLVVEEGGPAELLCQYSRPVQATWKMDEQEVRADGRRVVIEQDWT 2721
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
A L+ D+G Y+C E A L ++ + + + E V+ EG
Sbjct: 2722 VARLSFRPALPCDSGIYSC----EAAGTHVVALLQVQAK----NTVVRGLENVDTLEGGE 2773
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNAL--LLQVKKASMGDAGLYTCKV 1070
E +++ + + W ++ +H + N E+ + N L LL +K D +C+V
Sbjct: 2774 ALFECQLSRPEVAAHTWLLDDEPVHTSENAEVVYFENGLRHLLLLKNLRPQD----SCRV 2829
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLFNKHGEIESNVNLQVNERKKQEKIEGDLR 1772
G + I G L+I D+G Y CVA N GE + ++ L V+E + D
Sbjct: 1872 GNLKIQSSG--RLLQIAKALMEDAGRYTCVATNAAGETQQHIQLHVHEPPSLD----DAG 1925
Query: 1773 AMLKKTPVL 1799
ML +T V+
Sbjct: 1926 KMLNETVVV 1934
Score = 162 bits (409), Expect = 1e-39
Identities = 144/598 (24%), Positives = 229/598 (38%), Gaps = 11/598 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V V + L+C+ G P ++W K + + + + L +D+G
Sbjct: 2021 VAVVVNNLVRLECEARGIPAPSLTWLKDGSPVTSFVN-GIQVLSGGRILALTSAQISDTG 2079
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C A N+ GE L V + P+ + ++V + V C P +++
Sbjct: 2080 RYTCVAVNAAGEKQRDIDLRVY---VAPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT 2136
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W KDG PL P + S +N + L I +G+Y+C ATN G + + +
Sbjct: 2137 WLKDGHPLLKKPGL--SVTENGSVLKIEDAQVQDSGRYTCEATNVAGKTEKNYNVNIWVP 2194
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
N D A + + G C +G P + W K + + ++ L
Sbjct: 2195 PNISGSD-EAAQLTVIEGHLISLLCESSGIPPPNLIWKKKGSPVLADSAGRVRILSGGRQ 2253
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE--ETEGNSF 899
L I +K D G Y+C A N G L + I P+ + S E T G S
Sbjct: 2254 LQISVAEKSDAGLYSCMASNVAGTAKKDYSLQV---YIRPTISNSGSHPTEIIVTRGKSV 2310
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
LE V G +V W K+ + EI + ++Q+K + D G Y C N
Sbjct: 2311 SLECEVEGVPQPAVTWMKDGRPLTKGRGMEIM--DEGRVVQLKNVHVSDTGRYVCVAMNI 2368
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTP--VTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
AG + + P P + H TP ++V E + L+C G I WLK G
Sbjct: 2369 AGMTDRKYDLSVHTP--PSIIGNHRTPENISVVEKSSVSLNCEASGIPLPSITWLKDGWP 2426
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
+ S S +G +L DAG Y C N AG + +++
Sbjct: 2427 VNLSS--SLRILSGGRILRLMQTRTEDAGQYTCVVRNAAGEERKIFRLSVLVPPH----- 2479
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-------GKWRQLNQG 1592
+ G+ F + ++V EK + T +V G+P+P + W K L G
Sbjct: 2480 ----IMGENTF----EDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQLLKEDDTHHLMSG 2531
Query: 1593 GRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGD 1766
GR L+I + + +G Y C+A N G+ + +L V ++GD
Sbjct: 2532 GRF----------LQIVNAQVSHTGRYTCLASNTAGDKSKSFSLNVLVSPIIAGVDGD 2579
Score = 159 bits (403), Expect = 7e-39
Identities = 158/622 (25%), Positives = 237/622 (38%), Gaps = 25/622 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + SL C+ P ++W+K T L + + TL +D+G
Sbjct: 2585 VTVILNSPTSLVCEAYSYPPATITWFKNGTPLE--SNQNIRILPGGRTLQILNAQEDDAG 2642
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSR--------QLRDVQETVGLPVVFECAVS 341
Y C A N GE+ + V +PP ++ R+V+ V + EC
Sbjct: 2643 RYACVATNEAGEMIKHYEVKVY---IPPIINKGDLLGPGLSPREVKIKVNNTLTLECEAY 2699
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
S+SW+KDG+PLK ++ + TL I + S G+Y+C A+N G
Sbjct: 2700 AIPSASLSWYKDGQPLKSDDHV--TIAAGGHTLQIKEAQISDTGRYTCVASNVAGEDELD 2757
Query: 522 ARLILTEGRNPPFFDIPLAPV-------------DAVVGESADFECHVTGTQPIKVAWAK 662
+ + + PP F L + D ++ C + W K
Sbjct: 2758 FDVNI---QVPPSFQ-KLWEIGNRVDTGRRGEAKDVIINNPISLYCETNAAPAPTLTWYK 2813
Query: 663 DNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP 842
D + S + ++ L L I + D G+Y C AVNE G+DS + + L+P
Sbjct: 2814 DGHPLTS--SERVLILPGGRVLQIPRAKVEDAGRYMCVAVNEAGEDSLQYDIRV---LLP 2868
Query: 843 P---SFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNAL 1013
P L E V S +E +GS +W K+ + QLSCHVRGSEPI-RIQWLKAG 1247
+ AG + ++ + ++ + + + +V G + +C + + P+ W G
Sbjct: 2830 TFLAGDVVTSAFLTVRGWRLDVL--ESPQDASVRVGGPARFTCTLSEAVPVGEATWYING 2887
Query: 1248 REIKPSD 1268
++P D
Sbjct: 2888 AAVQPDD 2894
Score = 55.8 bits (133), Expect = 1e-07
Identities = 87/425 (20%), Positives = 144/425 (33%), Gaps = 10/425 (2%)
Frame = +3
Query: 513 SSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
S +A + LTE +N D G F+C V G V W KD R + +
Sbjct: 3532 SEAAPVFLTELQNQEVLD----------GYPVSFDCVVAGQPVPTVCWFKDGRMLEEDDH 3581
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET 872
Y IS + H I+ T ++G C A+ ++ L+ T
Sbjct: 3582 YMISEDQQGGHQLII----------TAVVPADMGVYRCMAENSVGVSSTKAELRVDLTST 3631
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAG 1052
ET ++ S S Y ++ E T +
Sbjct: 3632 DYETAADATET------SSYFSAQGYLSSREQEGTESTS--------------------- 3664
Query: 1053 LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFL-QLSCHVRGSEPIRI 1229
+E + P V ++ L + V+ G L + V+G R+
Sbjct: 3665 ---------------------EEGQLPQVVEE-LKDLQVAPGTRLAKFQVKVKGYPAPRL 3702
Query: 1230 QWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXX 1409
W K G+ + S+ + LE VT D G Y SN G+ S +++
Sbjct: 3703 YWFKDGQPLTASEHIHMADRKTLHTLEVVSVTCEDDGQYSAYISNAVGAAYSSARL-IVR 3761
Query: 1410 XXXXXXXXXXXXVDGKLF---FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGK--- 1571
V +L F+ S +V + ++ TF KV G P P V W + +
Sbjct: 3762 GPKDPEEKPASDVQQQLVPPRFLERFTSKKVKKGSSITFSVKVEGFPAPAVHWLREEAER 3821
Query: 1572 ---WRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
W + G + + L + D + G Y C+A N G+ + +L V+
Sbjct: 3822 GVLWIGRDTPG-YTVASSAQQHSLVLLDVGRPHQGTYTCIATNAAGQALCSASLHVSGLP 3880
Query: 1743 KQEKI 1757
K+ ++
Sbjct: 3881 KETRV 3885
Score = 55.5 bits (132), Expect = 2e-07
Identities = 31/97 (31%), Positives = 50/97 (51%), Gaps = 1/97 (1%)
Frame = +3
Query: 252 EQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFL-DN 428
+Q+ P+FSR RD + VG + EC VS + W KDG L DG + L D
Sbjct: 3297 KQQEGPAFSRTFRDTEVQVGDVLRLECVVSSKADVRACWLKDGVELTDGRHHHIDQLGDG 3356
Query: 429 VATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
+L + R+ AG+Y+C ++ G + SA ++++
Sbjct: 3357 TCSLLVTGLGRADAGRYTCQVSSKFGHVAHSACVVVS 3393
Database: RefSeq49_CP.fasta
Posted date: Oct 17, 2011 1:42 PM
Number of letters in database: 18,874,504
Number of sequences in database: 33,336
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33336
Number of Hits to DB: 75,140,982
Number of extensions: 1865291
Number of successful extensions: 11518
Number of sequences better than 1.0e-05: 178
Number of HSP's gapped: 7765
Number of HSP's successfully gapped: 929
Length of query: 667
Length of database: 18,874,504
Length adjustment: 109
Effective length of query: 558
Effective length of database: 15,240,880
Effective search space: 8504411040
Effective search space used: 8504411040
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)
+ TF +N
Sbjct: 2869 PVIKGANGDLPEEVTVLVNKSVTMECSSSGSPTPRSSWQKDGQPL--LEDERHTFLSNGR 2926
Query: 1014 LLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQL 1193
+LQV + + D G Y C N AGSA + + P P V + +TV F+ L
Sbjct: 2927 ILQVLNSQITDIGRYVCVAENTAGSAKKYFNFNVHVP--PSVIGPNPENLTVVVNNFISL 2984
Query: 1194 SCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAG 1373
+C V G P + WLK + IKP+ G L+ +D G+Y C A N AG
Sbjct: 2985 TCEVSGFPPPDLSWLKNEQPIKPNTNA--LIVPGGRTLQIIRAKVSDGGEYTCVAINQAG 3042
Query: 1374 SDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS-IRVVEKTTATFIAKVGGDPIPN 1550
K +T SE S + V E T+ + P P
Sbjct: 3043 ESKKKVSLTVYVPPSIKDHG------------SESLSVVNVREGTSVSLECGSNAVPPPV 3090
Query: 1551 VKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ W K R L + R+ I D L I +D+G Y C A N G + N +L V
Sbjct: 3091 ITWYK-NGRMLTESARLEI--LADGQMLHITKAEVSDTGQYVCRAINVAGRDDKNFHLNV 3147
Query: 1731 NERKKQEKIEGDLRAMLKKTPV 1796
E E ++ PV
Sbjct: 3148 YVPPSIEGPENEVTVETVSNPV 3169
Score = 159 bits (403), Expect = 7e-39
Identities = 147/572 (25%), Positives = 219/572 (38%), Gaps = 3/572 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ VTV +L C+ G P+ V+W K L + + +LV +D+
Sbjct: 3813 ISVTVNVQTTLACEATGIPKPSVNWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 3872
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C N GE + LTVQ +PPS + + D T P V C SG S+
Sbjct: 3873 TYECTVTNDAGEDKRAVDLTVQ---VPPSIADEPTDFLVTKHTPTVITCTASGVPFPSIH 3929
Query: 366 WFKDG---RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
W K+G P +G I +S + I T S AG+Y+C A N GSA L +
Sbjct: 3930 WMKNGVRLLPRGEGYRILSS-----GAIEILDTQLSHAGRYTCVARNSAGSAHRHVSLHV 3984
Query: 537 TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
E PP + +D ++ C TGT + W K+ + S G
Sbjct: 3985 QE---PPVIQPQPSELDVILNNPILLPCEATGTPSPFIIWQKEGISVISSGRSHAVLPRG 4041
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
L I + + D G Y C A N G +LN++ +PP + E + +
Sbjct: 4042 G--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ---VPPVISPHPKEYITVVD-KP 4095
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
L + G P + W+K+ I + I ++ LQ+ A GDAG YTC +N
Sbjct: 4096 IMLPCKADGLPPPDIMWHKDGHVIVESVRQRIL---SSGALQIAFAQPGDAGQYTCMAAN 4152
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
AGS+ ++ + + P + + H TV+E L C G I W K +
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIQSTEVH---YTVNENSQAVLPCVADGIPTPAINWKKDNVPL 4209
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
G +LE +V D+G Y C A+N AG DT +T
Sbjct: 4210 ANLLGKYTVEPYGELILE--NVVLEDSGTYTCIANNAAGEDTHTISLTVHVLPT------ 4261
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
F P + + + K G P+P + WT N
Sbjct: 4262 ---------FTELPGDVSLNKGEQLRLNCKATGIPLPKLTWTFN-----NNIIPAHFDSV 4307
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIES 1712
++L I +K DSG Y C A N G +++
Sbjct: 4308 NGHSELVIERISKEDSGTYVCTAENSVGFVKA 4339
Score = 157 bits (397), Expect = 3e-38
Identities = 151/599 (25%), Positives = 252/599 (42%), Gaps = 16/599 (2%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V +GD+ ++C+ +G P V W+KGD +L+P+ + + L + D+G+Y
Sbjct: 713 VALGDTTVMECKTSGVPPPQVKWFKGDLELKPSTF--LITDPLLGLLKIQETQDLDAGDY 770
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A N G + L V PP F ++ DV +G V C V G + W
Sbjct: 771 TCVAVNDAGRATGRITLDVGS---PPVFIQEPTDVSVEIGSNVTLPCYVQGYPEPKIKWR 827
Query: 372 K-DGRPLKDGPNIQTSFLDNVATLNIFQTD--RSFAGQYSCTATNPIGSASSSARLILTE 542
+ D P+ P S + + T ++F ++ S G Y C A N G S + +T
Sbjct: 828 RVDNMPIFSRP-FSVSSISQLRTGDLFISNLWASDKGTYICEAENQFGKIQSQTTVTVT- 885
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPI-KVAWAKDNREIRSGGNYQISYLENS 719
G P I + G+ C + PI + W K N + Y + S
Sbjct: 886 GLVAPLIGISPPVTSVIEGQQLTLPCALLAGNPIPERRWIK-NSAMLVQNPYITVRSDGS 944
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
H+ +++ G G+YTC A N G + T +++ ++P + + + EG
Sbjct: 945 LHIERVRLQDG--GEYTCVASNVAGITNKTTTVDV--HVLPT--IQHGQQILSTIEGIPV 998
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L + +G S+AW K E+ T++ + + + L V ++G Y C +N
Sbjct: 999 TLPCKASGIPKPSIAWSKKG-ELIFTSSAKFSAGADGSLYVVSPGG-EESGEYVCTATNA 1056
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTP-------VTVSEGEFLQLSCHVRGSEPIRIQWL 1238
AG A + + +P VF P ++V GE + L C V+G P I W
Sbjct: 1057 AGYA--KRKVQLTVYVRPRVFGDQRGPSQDKPVEISVFAGEEVTLPCEVKGLPPPIITWA 1114
Query: 1239 KAGREIKP-SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXX 1415
K + I P S R +F + + E + +D+G Y+C A+N+AG+ T K+
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETR---VSDSGMYLCVATNIAGNVTQSVKLN----- 1166
Query: 1416 XXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGG 1595
V K+ + ++V ++ A+ G P+P + W KG GG
Sbjct: 1167 --------VHVPPKIQRGPKVMKVQVGQRVDIPCSAQ--GTPLPVITWFKG-------GG 1209
Query: 1596 RIFI----HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIE 1760
+ + H + + L I+ +D+G+Y CVA N G E+ + L V E E +E
Sbjct: 1210 AVLVDGLQHIRHPDGTLSIKQAVLSDAGIYTCVATNIAGSDETEITLHVQEPPILEDLE 1268
Score = 150 bits (378), Expect = 5e-36
Identities = 147/592 (24%), Positives = 224/592 (37%), Gaps = 6/592 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDS---NDS 182
+ + S L+C G P ++W K L + H R +V F ++ S D
Sbjct: 3724 IHLNKSTLLECFAEGVPAPRITWRKDGAVLSGS-----HARYSVLENGFLRIQSAQVTDG 3778
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y+C A ++ G L V +PPS + ++ TV + C +G SV
Sbjct: 3779 GRYLCMATSAAGTDRRRIDLQVH---VPPSIAPGPTNISVTVNVQTTLACEATGIPKPSV 3835
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+G L N + L + +L I Y CT TN G + L +
Sbjct: 3836 NWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNDAGEDKRAVDLTV-- 3893
Query: 543 GRNPPFFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDN-REIRSGGNYQISYLE 713
+ PP I P D +V + C +G + W K+ R + G Y+I
Sbjct: 3894 -QVPP--SIADEPTDFLVTKHTPTVITCTASGVPFPSIHWMKNGVRLLPRGEGYRIL--- 3947
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN 893
+S + IL G+YTC A N G L+++E PP + SE ++ N
Sbjct: 3948 SSGAIEILDTQLSHAGRYTCVARNSAGSAHRHVSLHVQE---PPVIQPQPSE-LDVILNN 4003
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
L G+ + W K + + + L Q+ +A DAG Y C
Sbjct: 4004 PILLPCEATGTPSPFIIWQKEGISVISSGRSHAVLPRGGL--QISRAVREDAGTYMCVAQ 4061
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
N AG+AL + ++ P PV H + + L C G P I W K G
Sbjct: 4062 NPAGTALGKIKLNVQVP---PVISPHPKEYITVVDKPIMLPCKADGLPPPDIMWHKDGHV 4118
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
I S R + L+ DAG Y C A+NVAGS ++ +K+T
Sbjct: 4119 IVESVRQRIL---SSGALQIAFAQPGDAGQYTCMAANVAGSSSTSTKLTVHVPPRIQSTE 4175
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
V+ E + A G P P + W K N G+ +
Sbjct: 4176 VHYTVN---------------ENSQAVLPCVADGIPTPAINWKKDNVPLANLLGKYTVEP 4220
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDL 1769
G+ L + + DSG Y C+A N GE ++L V+ ++ GD+
Sbjct: 4221 YGE---LILENVVLEDSGTYTCIANNAAGEDTHTISLTVHVLPTFTELPGDV 4269
Score = 148 bits (374), Expect = 2e-35
Identities = 150/572 (26%), Positives = 226/572 (39%), Gaps = 7/572 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V + + L C+ GTP + W K + ++ + H L ++ D+G Y
Sbjct: 3999 VILNNPILLPCEATGTPSPFIIWQKEGISV--ISSGRSHAVLPRGGLQISRAVREDAGTY 4056
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
+C A+N G L VQ +PP S ++ V P++ C G P + W
Sbjct: 4057 MCVAQNPAGTALGKIKLNVQ---VPPVISPHPKEYITVVDKPIMLPCKADGLPPPDIMWH 4113
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDG + + +++ L + A L I AGQY+C A N GS+S+S +L +
Sbjct: 4114 KDGHVIVE--SVRQRILSSGA-LQIAFAQPGDAGQYTCMAANVAGSSSTSTKLTV---HV 4167
Query: 552 PPFFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDNREIRSG-GNYQISYLENSA 722
PP I V V E++ C G + W KDN + + G Y + E
Sbjct: 4168 PP--RIQSTEVHYTVNENSQAVLPCVADGIPTPAINWKKDNVPLANLLGKYTV---EPYG 4222
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + V D+G YTC A N G+D+ T L + + P+FT+ L V +G R
Sbjct: 4223 ELILENVVLEDSGTYTCIANNAAGEDTHTISLTVH---VLPTFTE-LPGDVSLNKGEQLR 4278
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L + G + W NN I P + N L +++ S D+G Y C N
Sbjct: 4279 LNCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVIERISKEDSGTYVCTAENSV 4334
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSE-GEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
G + +KE PPVF + G L+C V+G IQW + G +I+
Sbjct: 4335 GFVKAIGFVYVKE---PPVFKGDYPSNWIEPLGGNAILNCEVKGDPAPTIQWSRRGIDIE 4391
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
S R NG+ L DAGDY C A+N AG +T
Sbjct: 4392 ISHRIR-QLGNGS--LAIYGTVNEDAGDYTCVATNEAGVVERSMSLT------------- 4435
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
+ EP + + + G+P P + W++ QG I ++
Sbjct: 4436 --LQSTPIITLEPVETIINAGSKVILNCQATGEPRPTITWSR-------QGHSILWDERI 4486
Query: 1620 D---EAKLEIRDTTKTDSGLYRCVAFNKHGEI 1706
+ L I K D+ Y CVA N G +
Sbjct: 4487 NVLSNNSLHIAAAQKEDTSEYECVARNLMGSV 4518
Score = 146 bits (369), Expect = 6e-35
Identities = 147/594 (24%), Positives = 228/594 (38%), Gaps = 19/594 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V + L+C+ G P ++WYK + ++ + + QV +DS
Sbjct: 1557 VSALINSIIKLECETRGLPMPAITWYKDGQPVISSSQALYVEKGQFLHIPRAQV--SDSA 1614
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDV---QETVGLPVVFECAVSGSEPI 356
Y C N G S + V +PP L + Q V + EC +G+ P
Sbjct: 1615 AYKCLVTNVAGTAEKSFHVDVY---VPPVIEGDLAEPLNKQVKVAHSLTLECKAAGNPPP 1671
Query: 357 SVSWFKDGRPLKDGPNIQ-TSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
++W KDG P+K NI+ + + + + DR GQY C AT+ G +
Sbjct: 1672 VLTWLKDGVPVKASDNIRIEAGGKKLEITSALEVDR---GQYICVATSVAGEKEIKYEVD 1728
Query: 534 L-----TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQ 698
+ EG + + I +V + +C VTG+ + W KD + I ++
Sbjct: 1729 VLVPPAIEGGDETSYFI------VMVNNLLELDCQVTGSPLPTIMWLKDGQLIDERDGFR 1782
Query: 699 ISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE 878
I L N L I + DTG Y C A N G ++ + +PP+
Sbjct: 1783 I--LLNGHKLVIAQAQVSDTGLYRCVATNTAGDHRKEFEVTVH---VPPTIKSSGLSERA 1837
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
+ L+ G S+ W K+ ++ TA + +++ LLQ+ KA M DAG Y
Sbjct: 1838 VLKYKPITLQCIANGIPNPSITWLKDGQPVN-TAQGNLKIQSSGRLLQIAKALMEDAGRY 1896
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFDQ--HLTPVTVSEGEFLQLSCHVRGSEPIRIQ 1232
TC +N AG T + +PP D + TV +QL C G+ I
Sbjct: 1897 TCVATNAAGE---TQQHIQLHVHEPPSLDDAGKMLNETVVVNSPVQLECKAAGTPSPAIT 1953
Query: 1233 WLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXX 1412
W K R + SD S +F N ++ + DAG Y C A N AG+
Sbjct: 1954 WYKDNRPL--SDSSSVTFLNRGQIINIESAQITDAGIYKCVAINSAGA------------ 1999
Query: 1413 XXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG-------- 1568
V +F + VV + G P P++ W K
Sbjct: 2000 -TELFYSLQVHVPPSIF--GSNNMVAVVVNNLVRLECEARGIPAPSLTWLKDGSPVTSFV 2056
Query: 1569 KWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
Q+ GGRI L + +D+G Y CVA N GE + +++L+V
Sbjct: 2057 NGIQVLSGGRI----------LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Score = 145 bits (366), Expect = 1e-34
Identities = 153/619 (24%), Positives = 245/619 (39%), Gaps = 14/619 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT G++A L C + ++W + D +R T T M N++ L V +D+G
Sbjct: 529 VTVTPGETAVLTCLVVSAVGYNLTWQRNDRDIRLTDTAGMRILANLS-LELRSVKFSDAG 587
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY C N G + + FLTVQE PP + ++ T G V C+ +G ++
Sbjct: 588 EYRCVVSNEGGSSTEAVFLTVQE---PPKVTVMPKNQSFTAGSEVSIMCSATGYPKPKIA 644
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W + + + + N+ N D AG Y C A+N G ++ L E
Sbjct: 645 WTMNDVFIMGSHRYRMTSEGNLFIKNAVPKD---AGIYGCLASNSAGMDKQTSTLRYIEA 701
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P + + + +G++ EC +G P +V W K + E++ ++L
Sbjct: 702 ---PKLIVVQSELLVALGDTTVMECKTSGVPPPQVKWFKGDLELKPS-----TFLITDPL 753
Query: 726 LTILKVDKG---DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
L +LK+ + D G YTC AVN+ G+ + L++ PP F ++ ++ E G++
Sbjct: 754 LGLLKIQETQDLDAGDYTCVAVNDAGRATGRITLDVGS---PPVFIQEPTDVSVEI-GSN 809
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALL----LQVKKASMGDAGLYTC 1064
L V G + W V+ P + + + + L L + D G Y C
Sbjct: 810 VTLPCYVQGYPEPKIKW--RRVDNMPIFSRPFSVSSISQLRTGDLFISNLWASDKGTYIC 867
Query: 1065 KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVT-VSEGEFLQLSCHVRGSEPI-RIQWL 1238
+ N G +++ + P + PVT V EG+ L L C + PI +W+
Sbjct: 868 EAENQFGKIQSQTTVTVTGLVAPLIGIS--PPVTSVIEGQQLTLPCALLAGNPIPERRWI 925
Query: 1239 KAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXX 1418
K + + + L + V D G+Y C ASNVAG + V
Sbjct: 926 KNSAMLVQN---PYITVRSDGSLHIERVRLQDGGEYTCVASNVAGITNKTTTVDVHVLPT 982
Query: 1419 XXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR 1598
Q + +E T K G P P++ W+K +G
Sbjct: 983 IQHG---------------QQILSTIEGIPVTLPCKASGIPKPSIAWSK-------KGEL 1020
Query: 1599 IFI----HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGD 1766
IF G + L + +SG Y C A N G + V L V R ++ GD
Sbjct: 1021 IFTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNAAGYAKRKVQLTVYVR---PRVFGD 1077
Query: 1767 LRAMLKKTPV-LKKGAGEE 1820
R + PV + AGEE
Sbjct: 1078 QRGPSQDKPVEISVFAGEE 1096
Score = 145 bits (365), Expect = 2e-34
Identities = 141/529 (26%), Positives = 220/529 (41%), Gaps = 5/529 (0%)
Frame = +3
Query: 162 QVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVS 341
+V D G Y C A ++ G + TF V E PP + +V T G V C V
Sbjct: 488 EVTLADEGAYECVAVSTAGIGRAQTFFDVSE---PPPVIQVPSNVTVTPGETAVLTCLVV 544
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
+ +++W ++ R ++ L N+ +L + S AG+Y C +N GS++ +
Sbjct: 545 SAVGYNLTWQRNDRDIRLTDTAGMRILANL-SLELRSVKFSDAGEYRCVVSNEGGSSTEA 603
Query: 522 ARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
L + E PP + G C TG K+AW ++ I Y++
Sbjct: 604 VFLTVQE---PPKVTVMPKNQSFTAGSEVSIMCSATGYPKPKIAWTMNDVFIMGSHRYRM 660
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
+ + +L I D G Y C A N G D T+ L E P SE +
Sbjct: 661 T---SEGNLFIKNAVPKDAGIYGCLASNSAGMDKQTSTLRYIE---APKLIVVQSELLVA 714
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNAL-LLQVKKASMGDAGLY 1058
G++ +E + +G P V W+K ++E+ P+ + L LL++++ DAG Y
Sbjct: 715 L-GDTTVMECKTSGVPPPQVKWFKGDLELKPST---FLITDPLLGLLKIQETQDLDAGDY 770
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWL 1238
TC NDAG A T I + + PPVF Q T V+V G + L C+V+G +I+W
Sbjct: 771 TCVAVNDAGRA--TGRITL-DVGSPPVFIQEPTDVSVEIGSNVTLPCYVQGYPEPKIKWR 827
Query: 1239 KAGREIKPSDRCSFSFAN----GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXX 1406
+ + P FS ++ T L ++ +D G Y+C+A N G S++ VT
Sbjct: 828 RV--DNMPIFSRPFSVSSISQLRTGDLFISNLWASDKGTYICEAENQFGKIQSQTTVT-- 883
Query: 1407 XXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLN 1586
+ L +S P + + + A + G+PIP +W K L
Sbjct: 884 ----------VTGLVAPLIGISPPVTSVIEGQQLTLPCALLAGNPIPERRWIKNS-AMLV 932
Query: 1587 QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
Q I + G L I D G Y CVA N G + V+
Sbjct: 933 QNPYITVRSDG---SLHIERVRLQDGGEYTCVASNVAGITNKTTTVDVH 978
Score = 145 bits (365), Expect = 2e-34
Identities = 138/571 (24%), Positives = 215/571 (37%), Gaps = 4/571 (0%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENS 212
+L+C+ P ++W K +L+ AT ++ + L N D D+ Y C A N
Sbjct: 3640 TLECKSDAVPPPVITWLKNGERLQ--ATPRIRILSGGRYLQINNADLGDTANYTCVASNI 3697
Query: 213 VGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLK 392
G+ + LTV +PPS + + + + EC G ++W KDG L
Sbjct: 3698 AGKTTREFILTVN---VPPSIKSGPQSLVIHLNKSTLLECFAEGVPAPRITWRKDGAVLS 3754
Query: 393 DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIP 572
G + + S L+N L I + G+Y C AT+ +A + R I + PP
Sbjct: 3755 -GSHARYSVLEN-GFLRIQSAQVTDGGRYLCMATS---AAGTDRRRIDLQVHVPPSIAPG 3809
Query: 573 LAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKG 752
+ V C TG V W K+ + N L +S L I+
Sbjct: 3810 PTNISVTVNVQTTLACEATGIPKPSVNWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVD 3869
Query: 753 DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQP 932
DT Y C N+ G+D L ++ +PPS + ++ + T+ + +G
Sbjct: 3870 DTATYECTVTNDAGEDKRAVDLTVQ---VPPSIADEPTDFL-VTKHTPTVITCTASGVPF 3925
Query: 933 ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIV 1112
S+ W KN V + P + A +++ + AG YTC N AGSA S+
Sbjct: 3926 PSIHWMKNGVRLLPRGEGYRILSSGA--IEILDTQLSHAGRYTCVARNSAGSAHRHVSLH 3983
Query: 1113 IKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFAN 1292
++E PPV + + V + L C G+ I W K G + S R
Sbjct: 3984 VQE---PPVIQPQPSELDVILNNPILLPCEATGTPSPFIIWQKEGISVISSGRSHAVLPR 4040
Query: 1293 GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVS 1472
G L+ + DAG Y+C A N AG+ K K+ V
Sbjct: 4041 GG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLN---------------VQVPPVISP 4083
Query: 1473 EPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG----DEAKLEI 1640
P+ V K G P P++ W K G + + L+I
Sbjct: 4084 HPKEYITVVDKPIMLPCKADGLPPPDIMWHK--------DGHVIVESVRQRILSSGALQI 4135
Query: 1641 RDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
D+G Y C+A N G ++ L V+
Sbjct: 4136 AFAQPGDAGQYTCMAANVAGSSSTSTKLTVH 4166
Score = 143 bits (361), Expect = 5e-34
Identities = 141/581 (24%), Positives = 225/581 (38%), Gaps = 8/581 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G SL C+ +G P + W K + + + ++ + L + + +D+G Y
Sbjct: 2208 VIEGHLISLLCESSGIPPPNLIWKKKGSPVLADSAGRVRILSGGRQLQISVAEKSDAGLY 2267
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A N G L V + + ++ T G V EC V G +V+W
Sbjct: 2268 SCMASNVAGTAKKDYSLQVYIRPTISNSGSHPTEIIVTRGKSVSLECEVEGVPQPAVTWM 2327
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDGRPL G ++ +D + + S G+Y C A N G + + L+
Sbjct: 2328 KDGRPLTKGRGME--IMDEGRVVQLKNVHVSDTGRYVCVAMNIAG--MTDRKYDLSVHTP 2383
Query: 552 PPFFDIPLAP--VDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P P + V S C +G + W KD + + +I L
Sbjct: 2384 PSIIGNHRTPENISVVEKSSVSLNCEASGIPLPSITWLKDGWPVNLSSSLRI--LSGGRI 2441
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKLSETVEETEGNSFR 902
L +++ D GQYTC N G++ +L++ L+PP + E V+ E S
Sbjct: 2442 LRLMQTRTEDAGQYTCVVRNAAGEERKIFRLSV---LVPPHIMGENTFEDVKVKEKQSVT 2498
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L V G+ + W+K+ + + + LQ+ A + G YTC SN A
Sbjct: 2499 LTCEVTGNPVPEITWHKDGQLLKEDDTHHL--MSGGRFLQIVNAQVSHTGRYTCLASNTA 2556
Query: 1083 GSALCTSSI-VIKEPKKPPV-FDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
G + S+ V+ P V D VTV L C P I W K G +
Sbjct: 2557 GDKSKSFSLNVLVSPIIAGVDGDGSPEDVTVILNSPTSLVCEAYSYPPATITWFKNGTPL 2616
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
+ + + G L+ + + DAG Y C A+N AG +V
Sbjct: 2617 ESNQ--NIRILPGGRTLQILNAQEDDAGRYACVATNEAGEMIKHYEVKVYIPPIIN---- 2670
Query: 1437 XXXVDGKLFFVS-EPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
G L P+ +++ T T + P ++ W K + L + I
Sbjct: 2671 ----KGDLLGPGLSPREVKIKVNNTLTLECEAYAIPSASLSWYK-DGQPLKSDDHVTIAA 2725
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHG--EIESNVNLQV 1730
G L+I++ +D+G Y CVA N G E++ +VN+QV
Sbjct: 2726 GGH--TLQIKEAQISDTGRYTCVASNVAGEDELDFDVNIQV 2764
Score = 128 bits (321), Expect = 2e-29
Identities = 140/579 (24%), Positives = 211/579 (36%), Gaps = 4/579 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ V V + L C +G P ++W K L + V + QV+ D+G
Sbjct: 3538 MSVIVNNPLELTCMASGIPAPKITWMKDGRPLPQMDQMQTLGGGEVLRISSTQVE--DTG 3595
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV--GLPVVFECAVSGSEPIS 359
Y C A + G+ + V +PP+ + TV V EC P
Sbjct: 3596 RYTCLASSPAGDDDKEYLVRVH---VPPNIAGTGEPQDFTVLRNRQVTLECKSDAVPPPV 3652
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W K+G L+ P I+ L L I D Y+C A+N G ++ ILT
Sbjct: 3653 ITWLKNGERLQATPRIR--ILSGGRYLQINNADLGDTANYTCVASNIAG--KTTREFILT 3708
Query: 540 EGRNPPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
P I P V+ +S EC G ++ W KD + SG + + S LE
Sbjct: 3709 VNVPP---SIKSGPQSLVIHLNKSTLLECFAEGVPAPRITWRKDG-AVLSGSHARYSVLE 3764
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN 893
N L I D G+Y C A + G D L + +PPS + T
Sbjct: 3765 N-GFLRIQSAQVTDGGRYLCMATSAAGTDRRRIDLQVH---VPPSIAPG-PTNISVTVNV 3819
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
L G SV W KN ++ N ++ L + S+ D Y C V+
Sbjct: 3820 QTTLACEATGIPKPSVNWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
NDAG + ++ P P + D+ T V++ ++C G I W+K G
Sbjct: 3880 NDAGEDKRAVDLTVQVP--PSIADEP-TDFLVTKHTPTVITCTASGVPFPSIHWMKNGVR 3936
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
+ P ++G +E D + AG Y C A N AGS
Sbjct: 3937 LLPRGEGYRILSSG--AIEILDTQLSHAGRYTCVARNSAGS---------------AHRH 3979
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
V +P + V+ + G P P + W K ++ G +
Sbjct: 3980 VSLHVQEPPVIQPQPSELDVILNNPILLPCEATGTPSPFIIWQKEGISVISSGRSHAVLP 4039
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+G L+I + D+G Y CVA N G + L V
Sbjct: 4040 RGG---LQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Score = 97.4 bits (241), Expect = 4e-20
Identities = 94/355 (26%), Positives = 143/355 (40%), Gaps = 3/355 (0%)
Frame = +3
Query: 675 IRSGGNYQIS-YLENSAHLT--ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPP 845
+R+G + YL+ SA +T I +V D G Y C AV+ G ++ E PP
Sbjct: 464 VRNGATLGVDQYLKESASVTWDIEEVTLADEGAYECVAVSTAGIGRAQTFFDVSE---PP 520
Query: 846 SFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQV 1025
+ + V T G + L V + ++ W +N+ +I T + N L L++
Sbjct: 521 PVIQ-VPSNVTVTPGETAVLTCLVVSAVGYNLTWQRNDRDIRLTDTAGMRILAN-LSLEL 578
Query: 1026 KKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHV 1205
+ DAG Y C VSN+ GS+ + ++EP K V ++ + + G + + C
Sbjct: 579 RSVKFSDAGEYRCVVSNEGGSSTEAVFLTVQEPPKVTVMPKN---QSFTAGSEVSIMCSA 635
Query: 1206 RGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTS 1385
G +I W I S R + L K+ DAG Y C ASN AG D
Sbjct: 636 TGYPKPKIAWTMNDVFIMGSHRYRMTSEGN---LFIKNAVPKDAGIYGCLASNSAGMDKQ 692
Query: 1386 KSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK 1565
S + ++ V + + + + TT K G P P VKW K
Sbjct: 693 TSTL--------------RYIEAPKLIVVQSELLVALGDTT-VMECKTSGVPPPQVKWFK 737
Query: 1566 GKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
G L F+ L+I++T D+G Y CVA N G + L V
Sbjct: 738 G---DLELKPSTFLITDPLLGLLKIQETQDLDAGDYTCVAVNDAGRATGRITLDV 789
Score = 92.8 bits (229), Expect = 1e-18
Identities = 78/268 (29%), Positives = 119/268 (44%), Gaps = 5/268 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFR--NNVATLVFNQVDSND 179
V + G+ L C+ G P ++W + + HF N + LV ++ D
Sbjct: 4269 VSLNKGEQLRLNCKATGIPLPKLTWTFNNNII------PAHFDSVNGHSELVIERISKED 4322
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQL-RDVQETVGLPVVFECAVSGSEPI 356
SG Y+C AENSVG V + F+ V+E PP F + E +G + C V G
Sbjct: 4323 SGTYVCTAENSVGFVKAIGFVYVKE---PPVFKGDYPSNWIEPLGGNAILNCEVKGDPAP 4379
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
++ W + G ++ I+ L N +L I+ T AG Y+C ATN G S L L
Sbjct: 4380 TIQWSRRGIDIEISHRIRQ--LGN-GSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTL 4436
Query: 537 TEGRNPPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
++ P I L PV+ ++ G C TG + W++ I + +I+ L
Sbjct: 4437 ---QSTPI--ITLEPVETIINAGSKVILNCQATGEPRPTITWSRQGHSIL--WDERINVL 4489
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVG 794
N++ L I K DT +Y C A N +G
Sbjct: 4490 SNNS-LHIAAAQKEDTSEYECVARNLMG 4516
>ref|XP_002694295.1| PREDICTED: hemicentin 1 [Bos taurus].
Length = 5635
Score = 191 bits (486), Expect = 2e-48
Identities = 152/581 (26%), Positives = 248/581 (42%), Gaps = 5/581 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V G S SL+C P ++WYK L +A ++ + L + + +D+G
Sbjct: 3069 VNVREGTSVSLECGSNAVPPPVITWYKNGRMLTESA--RLEILADGQMLHITKAEVSDTG 3126
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQ-ETVGLPVVFECAVSGSEPISV 362
+Y+CRA N G + L V +PPS +V ETV PV C +G P S+
Sbjct: 3127 QYVCRAINVAGRDDKNFHLNVY---VPPSIEGPENEVTVETVSNPVTLTCDATGIPPPSI 3183
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+ RP+++ +++ L L I ++ S +G Y+C A+N G A L +
Sbjct: 3184 AWLKNHRPIENSGSLEVHILSGGRKLQIARSQHSDSGNYTCIASNMEGKAQKHYILSIQV 3243
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
N +IP + V ++GE+ + C G + W KD + I S +I + +
Sbjct: 3244 PPNVADAEIP-SEVSVLLGENVELVCSANGIPTPLIQWLKDGKPIVSSETERIRVAADGS 3302
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF--TKKLSETVEETEGNS 896
L I D G+YTC A N G++ LN+ +PP+ K+ +E + S
Sbjct: 3303 TLNIYGALPSDMGKYTCVATNPAGEEDRIFNLNV---YVPPAIRGNKEEAEKLMALVDTS 3359
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
+E R G P + W KN + + + I + ++++ +A D +YTC SN
Sbjct: 3360 INIECRATGMPPPQINWLKNGLPL--PLSSHIRLLSGGQVIRIVRAQASDVAVYTCVASN 3417
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHL--TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
AG S+ + PP D + +T+ +G ++C G+ R+ WL+ GR
Sbjct: 3418 RAGVDNKHFSLQV---LVPPSLDNGMGTEEITIVKGSSTSMTCFTDGTPAPRMSWLRDGR 3474
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
+ S S + VL+ D+G Y C ASN AG + SK +
Sbjct: 3475 PLGLDAHLSIS--SQGMVLQLIKAETEDSGRYTCIASNEAG-EVSKHFI--------LKI 3523
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
++G EP + V+ G P P + W K R L Q + +
Sbjct: 3524 LEPPHINGS----EEPMEMSVIVNNPLELTCMASGIPAPKITWMK-DGRPLPQMDQ--MQ 3576
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
G L I T D+G Y C+A + G+ + ++V+
Sbjct: 3577 TLGGGEVLRISSTQVEDTGRYTCLASSPAGDDDKEYLVRVH 3617
Score = 183 bits (465), Expect = 4e-46
Identities = 155/595 (26%), Positives = 241/595 (40%), Gaps = 22/595 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V V L+C+ AGTP ++WYK + L +++ R + + Q+ D+G Y
Sbjct: 1932 VVVNSPVQLECKAAGTPSPAITWYKDNRPLSDSSSVTFLNRGQIINIESAQI--TDAGIY 1989
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A NS G ++ F ++Q +PPS V V V EC G S++W
Sbjct: 1990 KCVAINSAG--ATELFYSLQVH-VPPSIFGSNNMVAVVVNNLVRLECEARGIPAPSLTWL 2046
Query: 372 KDGRPLKDGPNIQTSFLDNVATLN------IFQTDRSFAGQYSCTATNPIGSASSSARL- 530
KDG P+ TSF++ + L+ + S G+Y+C A N G L
Sbjct: 2047 KDGSPV-------TSFVNGIQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLR 2099
Query: 531 ------ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
I+ E +N V ++ ++ + C P + W KD +
Sbjct: 2100 VYVAPNIMGEEQN----------VSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPG 2149
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET 872
+S EN + L I D+G+YTC A N GK +NI +PP+ + E
Sbjct: 2150 --LSVTENGSVLKIEDAQVQDSGRYTCEATNVAGKTEKNYNVNI---WVPPNISGS-DEA 2203
Query: 873 VEET--EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGD 1046
+ T EG+ L +G P ++ W K + + + + LQ+ A D
Sbjct: 2204 AQLTVIEGHLISLLCESSGIPPPNLIWKKKGSPVLADSAGRVRILSGGRQLQISVAEKSD 2263
Query: 1047 AGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIR 1226
AGLY+C SN AG+A S+ + H T + V+ G+ + L C V G
Sbjct: 2264 AGLYSCMASNVAGTAKKDYSLQVYIRPTISNSGSHPTEIIVTRGKSVSLECEVEGVPQPA 2323
Query: 1227 IQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXX 1406
+ W+K GR + + V++ K+V +D G YVC A N+AG K ++
Sbjct: 2324 VTWMKDGRPLTKGR--GMEIMDEGRVVQLKNVHVSDTGRYVCVAMNIAGMTDRKYDLSVH 2381
Query: 1407 XXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKW---- 1574
P++I VVEK++ + + G P+P++ W K W
Sbjct: 2382 TPPSIIGNHRT------------PENISVVEKSSVSLNCEASGIPLPSITWLKDGWPVNL 2429
Query: 1575 ---RQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
++ GGRI L + T D+G Y CV N GE L V
Sbjct: 2430 SSSLRILSGGRI----------LRLMQTRTEDAGQYTCVVRNAAGEERKIFRLSV 2474
Score = 175 bits (443), Expect = 2e-43
Identities = 169/609 (27%), Positives = 261/609 (42%), Gaps = 14/609 (2%)
Frame = +3
Query: 3 PVKVTV--GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSN 176
PV+++V G+ +L C++ G P ++W K + P + + + +V +
Sbjct: 1086 PVEISVFAGEEVTLPCEVKGLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRV--S 1143
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
DSG Y+C A N G V+ S L V +PP R + ++ VG V C+ G+
Sbjct: 1144 DSGMYLCVATNIAGNVTQSVKLNVH---VPPKIQRGPKVMKVQVGQRVDIPCSAQGTPLP 1200
Query: 357 SVSWFKDGRP-LKDGPNIQTSFLDNV----ATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
++WFK G L DG L ++ TL+I Q S AG Y+C ATN GS +
Sbjct: 1201 VITWFKGGGAVLVDG-------LQHIRHPDGTLSIKQAVLSDAGIYTCVATNIAGSDETE 1253
Query: 522 ARLILTEGRNPPFFDIPLAPVDA-----VVGESADFECHVTGTQPIKVAWAKDNREIRSG 686
L + E PP + P + V + F C GT + W ++ RE+ +G
Sbjct: 1254 ITLHVQE---PPILEDLEPPYNTPFQERVANQRIAFPCPAKGTPKPTIKWLRNGREL-TG 1309
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLS 866
IS LE+ L I V D G+Y C AVNE G + + N+K + P K+
Sbjct: 1310 QEPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG--TTERRYNLKVHVPPVIKDKEQV 1367
Query: 867 ETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGD 1046
V L V G+ + WYK++V++ T + I NN +L++ + S D
Sbjct: 1368 TNVSVLVNQPTSLFCEVEGTPSPIIMWYKDDVQV--TESSSIQIVNNGKILKLFRTSPED 1425
Query: 1047 AGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP--VTVSEGEFLQLSCHVRGSEP 1220
AG Y+CK N AG++ +I + PP +P V+V + L C V+G+
Sbjct: 1426 AGGYSCKAVNVAGTSQKHFNI---DVLVPPTIIGAGSPGEVSVVLNQNTTLECQVKGTPF 1482
Query: 1221 IRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
I+WLK G+ + D + + VL K+ ++D G Y C SN AG K+T
Sbjct: 1483 PVIRWLKDGKPLFLGDP-NIEILDRGQVLHLKNARRSDKGRYQCSVSNAAGKQAKDIKLT 1541
Query: 1401 XXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQ 1580
V + SI +E T G P+P + W K
Sbjct: 1542 IYIPPSIKGGNVTTEVSALI------NSIIKLECETR-------GLPMPAITWYKDGQPV 1588
Query: 1581 LNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIE 1760
++ +++ +KG L I +DS Y+C+ N G E + ++ V IE
Sbjct: 1589 ISSSQALYV-EKGQ--FLHIPRAQVSDSAAYKCLVTNVAGTAEKSFHVDV---YVPPVIE 1642
Query: 1761 GDLRAMLKK 1787
GDL L K
Sbjct: 1643 GDLAEPLNK 1651
Score = 175 bits (443), Expect = 2e-43
Identities = 151/581 (25%), Positives = 239/581 (41%), Gaps = 8/581 (1%)
Frame = +3
Query: 15 TVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYI 194
TV + +L C G P ++W K + + + ++H + L + +DSG Y
Sbjct: 3164 TVSNPVTLTCDATGIPPPSIAWLKNHRPIENSGSLEVHILSGGRKLQIARSQHSDSGNYT 3223
Query: 195 CRAENSVGEVSSSTFLTVQEQKLPPSFSRQL--RDVQETVGLPVVFECAVSGSEPISVSW 368
C A N G+ L++Q +PP+ + +V +G V C+ +G + W
Sbjct: 3224 CIASNMEGKAQKHYILSIQ---VPPNVADAEIPSEVSVLLGENVELVCSANGIPTPLIQW 3280
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
KDG+P+ + + +TLNI+ S G+Y+C ATNP G R+
Sbjct: 3281 LKDGKPIVSSETERIRVAADGSTLNIYGALPSDMGKYTCVATNPAGEED---RIFNLNVY 3337
Query: 549 NPPFFDIPLAPVD---AVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
PP + A+V S + EC TG P ++ W K+ + + ++ L
Sbjct: 3338 VPPAIRGNKEEAEKLMALVDTSINIECRATGMPPPQINWLKNGLPLPLSSHIRL--LSGG 3395
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKL-SETVEETEGNS 896
+ I++ D YTC A N G D+ L + L+PPS + +E + +G+S
Sbjct: 3396 QVIRIVRAQASDVAVYTCVASNRAGVDNKHFSLQV---LVPPSLDNGMGTEEITIVKGSS 3452
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
+ G+ ++W ++ + A+ I+ + ++LQ+ KA D+G YTC SN
Sbjct: 3453 TSMTCFTDGTPAPRMSWLRDGRPLGLDAHLSIS--SQGMVLQLIKAETEDSGRYTCIASN 3510
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSE--GEFLQLSCHVRGSEPIRIQWLKAGR 1250
+AG S I + +PP + P+ +S L+L+C G +I W+K GR
Sbjct: 3511 EAGEV---SKHFILKILEPPHINGSEEPMEMSVIVNNPLELTCMASGIPAPKITWMKDGR 3567
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
+ D+ G VL D G Y C AS+ AG D + V
Sbjct: 3568 PLPQMDQ--MQTLGGGEVLRISSTQVEDTGRYTCLASSPAGDDDKEYLVRVH-------- 3617
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
V + EPQ V+ T K P P + W K R L RI I
Sbjct: 3618 -----VPPNIAGTGEPQDFTVLRNRQVTLECKSDAVPPPVITWLKNGER-LQATPRIRIL 3671
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
G L+I + D+ Y CVA N G+ L VN
Sbjct: 3672 SGG--RYLQINNADLGDTANYTCVASNIAGKTTREFILTVN 3710
Score = 174 bits (440), Expect = 3e-43
Identities = 152/569 (26%), Positives = 234/569 (41%), Gaps = 2/569 (0%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENS 212
+LQC G P ++W K + TA + +++ L + D+G Y C A N+
Sbjct: 1845 TLQCIANGIPNPSITWLKDGQPVN-TAQGNLKIQSSGRLLQIAKALMEDAGRYTCVATNA 1903
Query: 213 VGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGL--PVVFECAVSGSEPISVSWFKDGRP 386
GE L V E PPS + + ETV + PV EC +G+ +++W+KD RP
Sbjct: 1904 AGETQQHIQLHVHE---PPSLDDAGKMLNETVVVNSPVQLECKAAGTPSPAITWYKDNRP 1960
Query: 387 LKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFD 566
L D ++ +FL+ +NI + AG Y C A N SA ++ + PP
Sbjct: 1961 LSDSSSV--TFLNRGQIINIESAQITDAGIYKCVAIN---SAGATELFYSLQVHVPPSIF 2015
Query: 567 IPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVD 746
V VV EC G + W KD + S N I L L +
Sbjct: 2016 GSNNMVAVVVNNLVRLECEARGIPAPSLTWLKDGSPVTSFVN-GIQVLSGGRILALTSAQ 2074
Query: 747 KGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGS 926
DTG+YTC AVN G+ L + + P+ + + V + L +
Sbjct: 2075 ISDTGRYTCVAVNAAGEKQRDIDLRV---YVAPNIMGE-EQNVSVLISQAVELLCQSDAI 2130
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS 1106
P ++ W K+ + +T N +L+++ A + D+G YTC+ +N AG +
Sbjct: 2131 PPPTLTWLKDGHPLLKKPGLSVT--ENGSVLKIEDAQVQDSGRYTCEATNVAGKTEKNYN 2188
Query: 1107 IVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSF 1286
+ I P D+ +TV EG + L C G P + W K G +
Sbjct: 2189 VNIWVPPNISGSDE-AAQLTVIEGHLISLLCESSGIPPPNLIWKKKGSPVLADSAGRVRI 2247
Query: 1287 ANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFF 1466
+G L+ K+DAG Y C ASNVAG T+K +
Sbjct: 2248 LSGGRQLQISVAEKSDAGLYSCMASNVAG--TAKKDYSLQVYIRPTISNSG--------- 2296
Query: 1467 VSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRD 1646
S P I V + + +V G P P V W K R L +G + I +G +++++
Sbjct: 2297 -SHPTEIIVTRGKSVSLECEVEGVPQPAVTWMK-DGRPLTKGRGMEIMDEG--RVVQLKN 2352
Query: 1647 TTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
+D+G Y CVA N G + +L V+
Sbjct: 2353 VHVSDTGRYVCVAMNIAGMTDRKYDLSVH 2381
Score = 166 bits (420), Expect = 7e-41
Identities = 147/581 (25%), Positives = 229/581 (39%), Gaps = 6/581 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V V + SL C+++G P +SW K + ++P + ++ +V +D GEY
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKPNTNALIVPGGRTLQIIRAKV--SDGGEY 3033
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSF----SRQLRDVQETVGLPVVFECAVSGSEPIS 359
C A N GE LTV +PPS S L V G V EC + P
Sbjct: 3034 TCVAINQAGESKKKVSLTVY---VPPSIKDHGSESLSVVNVREGTSVSLECGSNAVPPPV 3090
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W+K+GR L + ++ L + L+I + + S GQY C A N G + L +
Sbjct: 3091 ITWYKNGRMLTESARLE--ILADGQMLHITKAEVSDTGQYVCRAINVAGRDDKNFHLNVY 3148
Query: 540 EGRNPPFFDIPLAPVDA-VVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
PP + P V V C TG P +AW K++R I + G+ ++ L
Sbjct: 3149 V---PPSIEGPENEVTVETVSNPVTLTCDATGIPPPSIAWLKNHRPIENSGSLEVHILSG 3205
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK-KLSETVEETEGN 893
L I + D+G YTC A N GK L+I+ +PP+ ++ V G
Sbjct: 3206 GRKLQIARSQHSDSGNYTCIASNMEGKAQKHYILSIQ---VPPNVADAEIPSEVSVLLGE 3262
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
+ L G + W K+ I + I + L + A D G YTC +
Sbjct: 3263 NVELVCSANGIPTPLIQWLKDGKPIVSSETERIRVAADGSTLNIYGALPSDMGKYTCVAT 3322
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
N AG ++ + P + + + + C G P +I WLK G
Sbjct: 3323 NPAGEEDRIFNLNVYVPPAIRGNKEEAEKLMALVDTSINIECRATGMPPPQINWLKNGLP 3382
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
+ S +G V+ +D Y C ASN AG D +
Sbjct: 3383 LPLSSH--IRLLSGGQVIRIVRAQASDVAVYTCVASNRAGVDNKHFSLQVL--------- 3431
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
V L + I +V+ ++ + G P P + W + R L + I
Sbjct: 3432 ----VPPSLDNGMGTEEITIVKGSSTSMTCFTDGTPAPRMSWLRDG-RPLGLDAHLSISS 3486
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+G +L +T DSG Y C+A N+ GE+ + L++ E
Sbjct: 3487 QGMVLQLIKAETE--DSGRYTCIASNEAGEVSKHFILKILE 3525
Score = 162 bits (410), Expect = 1e-39
Identities = 158/609 (25%), Positives = 238/609 (39%), Gaps = 11/609 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V V SL C++ GTP + WYK D ++ T + + NN L + D+G
Sbjct: 1370 VSVLVNQPTSLFCEVEGTPSPIIMWYKDDVQV--TESSSIQIVNNGKILKLFRTSPEDAG 1427
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C+A N G + V +PP+ + +V + EC V G+
Sbjct: 1428 GYSCKAVNVAGTSQKHFNIDVL---VPPTIIGAGSPGEVSVVLNQNTTLECQVKGTPFPV 1484
Query: 360 VSWFKDGRPLKDG-PNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
+ W KDG+PL G PNI+ LD L++ RS G+Y C+ +N G + +L +
Sbjct: 1485 IRWLKDGKPLFLGDPNIE--ILDRGQVLHLKNARRSDKGRYQCSVSNAAGKQAKDIKLTI 1542
Query: 537 -----TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
+G N V A++ EC G + W KD + + S Q
Sbjct: 1543 YIPPSIKGGNVT------TEVSALINSIIKLECETRGLPMPAITWYKDGQPVISSS--QA 1594
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
Y+E L I + D+ Y C N G + +++ +PP L+E + +
Sbjct: 1595 LYVEKGQFLHIPRAQVSDSAAYKCLVTNVAGTAEKSFHVDV---YVPPVIEGDLAEPLNK 1651
Query: 882 TE--GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGL 1055
+S LE + AG+ P + W K+ V + + N I + L++ A D G
Sbjct: 1652 QVKVAHSLTLECKAAGNPPPVLTWLKDGVPVKASDNIRI--EAGGKKLEITSALEVDRGQ 1709
Query: 1056 YTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQW 1235
Y C ++ AG + + P D+ + V L+L C V GS I W
Sbjct: 1710 YICVATSVAGEKEIKYEVDVLVPPAIEGGDE-TSYFIVMVNNLLELDCQVTGSPLPTIMW 1768
Query: 1236 LKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXX 1415
LK G+ I +R F L +D G Y C A+N AG + +VT
Sbjct: 1769 LKDGQLI--DERDGFRILLNGHKLVIAQAQVSDTGLYRCVATNTAGDHRKEFEVTVHVPP 1826
Query: 1416 XXXXXXXXXXVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDPIPNVKWTKGKWRQLNQG 1592
S S R V K T G P P++ W K
Sbjct: 1827 TIK---------------SSGLSERAVLKYKPITLQCIANGIPNPSITWLKDGQPVNTAQ 1871
Query: 1593 GRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLR 1772
G + I G L+I D+G Y CVA N GE + ++ L V+E + D
Sbjct: 1872 GNLKIQSSG--RLLQIAKALMEDAGRYTCVATNAAGETQQHIQLHVHEPPSLD----DAG 1925
Query: 1773 AMLKKTPVL 1799
ML +T V+
Sbjct: 1926 KMLNETVVV 1934
Score = 162 bits (409), Expect = 1e-39
Identities = 144/598 (24%), Positives = 229/598 (38%), Gaps = 11/598 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V V + L+C+ G P ++W K + + + + L +D+G
Sbjct: 2021 VAVVVNNLVRLECEARGIPAPSLTWLKDGSPVTSFVN-GIQVLSGGRILALTSAQISDTG 2079
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C A N+ GE L V + P+ + ++V + V C P +++
Sbjct: 2080 RYTCVAVNAAGEKQRDIDLRVY---VAPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT 2136
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W KDG PL P + S +N + L I +G+Y+C ATN G + + +
Sbjct: 2137 WLKDGHPLLKKPGL--SVTENGSVLKIEDAQVQDSGRYTCEATNVAGKTEKNYNVNIWVP 2194
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
N D A + + G C +G P + W K + + ++ L
Sbjct: 2195 PNISGSD-EAAQLTVIEGHLISLLCESSGIPPPNLIWKKKGSPVLADSAGRVRILSGGRQ 2253
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE--ETEGNSF 899
L I +K D G Y+C A N G L + I P+ + S E T G S
Sbjct: 2254 LQISVAEKSDAGLYSCMASNVAGTAKKDYSLQV---YIRPTISNSGSHPTEIIVTRGKSV 2310
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
LE V G +V W K+ + EI + ++Q+K + D G Y C N
Sbjct: 2311 SLECEVEGVPQPAVTWMKDGRPLTKGRGMEIM--DEGRVVQLKNVHVSDTGRYVCVAMNI 2368
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTP--VTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
AG + + P P + H TP ++V E + L+C G I WLK G
Sbjct: 2369 AGMTDRKYDLSVHTP--PSIIGNHRTPENISVVEKSSVSLNCEASGIPLPSITWLKDGWP 2426
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
+ S S +G +L DAG Y C N AG + +++
Sbjct: 2427 VNLSS--SLRILSGGRILRLMQTRTEDAGQYTCVVRNAAGEERKIFRLSVLVPPH----- 2479
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-------GKWRQLNQG 1592
+ G+ F + ++V EK + T +V G+P+P + W K L G
Sbjct: 2480 ----IMGENTF----EDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQLLKEDDTHHLMSG 2531
Query: 1593 GRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGD 1766
GR L+I + + +G Y C+A N G+ + +L V ++GD
Sbjct: 2532 GRF----------LQIVNAQVSHTGRYTCLASNTAGDKSKSFSLNVLVSPIIAGVDGD 2579
Score = 159 bits (403), Expect = 7e-39
Identities = 158/622 (25%), Positives = 237/622 (38%), Gaps = 25/622 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V V + SL C+ P ++W+K T L + + TL +D+G
Sbjct: 2585 VTVILNSPTSLVCEAYSYPPATITWFKNGTPLE--SNQNIRILPGGRTLQILNAQEDDAG 2642
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSR--------QLRDVQETVGLPVVFECAVS 341
Y C A N GE+ + V +PP ++ R+V+ V + EC
Sbjct: 2643 RYACVATNEAGEMIKHYEVKVY---IPPIINKGDLLGPGLSPREVKIKVNNTLTLECEAY 2699
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
S+SW+KDG+PLK ++ + TL I + S G+Y+C A+N G
Sbjct: 2700 AIPSASLSWYKDGQPLKSDDHV--TIAAGGHTLQIKEAQISDTGRYTCVASNVAGEDELD 2757
Query: 522 ARLILTEGRNPPFFDIPLAPV-------------DAVVGESADFECHVTGTQPIKVAWAK 662
+ + + PP F L + D ++ C + W K
Sbjct: 2758 FDVNI---QVPPSFQ-KLWEIGNRVDTGRRGEAKDVIINNPISLYCETNAAPAPTLTWYK 2813
Query: 663 DNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP 842
D + S + ++ L L I + D G+Y C AVNE G+DS + + L+P
Sbjct: 2814 DGHPLTS--SERVLILPGGRVLQIPRAKVEDAGRYMCVAVNEAGEDSLQYDIRV---LLP 2868
Query: 843 P---SFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNAL 1013
P L E V S +E +GS +W K+ + + TF +N
Sbjct: 2869 PVIKGANGDLPEEVTVLVNKSVTMECSSSGSPTPRSSWQKDGQPL--LEDERHTFLSNGR 2926
Query: 1014 LLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQL 1193
+LQV + + D G Y C N AGSA + + P P V + +TV F+ L
Sbjct: 2927 ILQVLNSQITDIGRYVCVAENTAGSAKKYFNFNVHVP--PSVIGPNPENLTVVVNNFISL 2984
Query: 1194 SCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAG 1373
+C V G P + WLK + IKP+ G L+ +D G+Y C A N AG
Sbjct: 2985 TCEVSGFPPPDLSWLKNEQPIKPNTNA--LIVPGGRTLQIIRAKVSDGGEYTCVAINQAG 3042
Query: 1374 SDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS-IRVVEKTTATFIAKVGGDPIPN 1550
K +T SE S + V E T+ + P P
Sbjct: 3043 ESKKKVSLTVYVPPSIKDHG------------SESLSVVNVREGTSVSLECGSNAVPPPV 3090
Query: 1551 VKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ W K R L + R+ I D L I +D+G Y C A N G + N +L V
Sbjct: 3091 ITWYK-NGRMLTESARLEI--LADGQMLHITKAEVSDTGQYVCRAINVAGRDDKNFHLNV 3147
Query: 1731 NERKKQEKIEGDLRAMLKKTPV 1796
E E ++ PV
Sbjct: 3148 YVPPSIEGPENEVTVETVSNPV 3169
Score = 159 bits (403), Expect = 7e-39
Identities = 147/572 (25%), Positives = 219/572 (38%), Gaps = 3/572 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ VTV +L C+ G P+ V+W K L + + +LV +D+
Sbjct: 3813 ISVTVNVQTTLACEATGIPKPSVNWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 3872
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C N GE + LTVQ +PPS + + D T P V C SG S+
Sbjct: 3873 TYECTVTNDAGEDKRAVDLTVQ---VPPSIADEPTDFLVTKHTPTVITCTASGVPFPSIH 3929
Query: 366 WFKDG---RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
W K+G P +G I +S + I T S AG+Y+C A N GSA L +
Sbjct: 3930 WMKNGVRLLPRGEGYRILSS-----GAIEILDTQLSHAGRYTCVARNSAGSAHRHVSLHV 3984
Query: 537 TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
E PP + +D ++ C TGT + W K+ + S G
Sbjct: 3985 QE---PPVIQPQPSELDVILNNPILLPCEATGTPSPFIIWQKEGISVISSGRSHAVLPRG 4041
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
L I + + D G Y C A N G +LN++ +PP + E + +
Sbjct: 4042 G--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ---VPPVISPHPKEYITVVD-KP 4095
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
L + G P + W+K+ I + I ++ LQ+ A GDAG YTC +N
Sbjct: 4096 IMLPCKADGLPPPDIMWHKDGHVIVESVRQRIL---SSGALQIAFAQPGDAGQYTCMAAN 4152
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
AGS+ ++ + + P + + H TV+E L C G I W K +
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIQSTEVH---YTVNENSQAVLPCVADGIPTPAINWKKDNVPL 4209
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
G +LE +V D+G Y C A+N AG DT +T
Sbjct: 4210 ANLLGKYTVEPYGELILE--NVVLEDSGTYTCIANNAAGEDTHTISLTVHVLPT------ 4261
Query: 1437 XXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
F P + + + K G P+P + WT N
Sbjct: 4262 ---------FTELPGDVSLNKGEQLRLNCKATGIPLPKLTWTFN-----NNIIPAHFDSV 4307
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIES 1712
++L I +K DSG Y C A N G +++
Sbjct: 4308 NGHSELVIERISKEDSGTYVCTAENSVGFVKA 4339
Score = 157 bits (397), Expect = 3e-38
Identities = 151/599 (25%), Positives = 252/599 (42%), Gaps = 16/599 (2%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V +GD+ ++C+ +G P V W+KGD +L+P+ + + L + D+G+Y
Sbjct: 713 VALGDTTVMECKTSGVPPPQVKWFKGDLELKPSTF--LITDPLLGLLKIQETQDLDAGDY 770
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A N G + L V PP F ++ DV +G V C V G + W
Sbjct: 771 TCVAVNDAGRATGRITLDVGS---PPVFIQEPTDVSVEIGSNVTLPCYVQGYPEPKIKWR 827
Query: 372 K-DGRPLKDGPNIQTSFLDNVATLNIFQTD--RSFAGQYSCTATNPIGSASSSARLILTE 542
+ D P+ P S + + T ++F ++ S G Y C A N G S + +T
Sbjct: 828 RVDNMPIFSRP-FSVSSISQLRTGDLFISNLWASDKGTYICEAENQFGKIQSQTTVTVT- 885
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPI-KVAWAKDNREIRSGGNYQISYLENS 719
G P I + G+ C + PI + W K N + Y + S
Sbjct: 886 GLVAPLIGISPPVTSVIEGQQLTLPCALLAGNPIPERRWIK-NSAMLVQNPYITVRSDGS 944
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
H+ +++ G G+YTC A N G + T +++ ++P + + + EG
Sbjct: 945 LHIERVRLQDG--GEYTCVASNVAGITNKTTTVDV--HVLPT--IQHGQQILSTIEGIPV 998
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L + +G S+AW K E+ T++ + + + L V ++G Y C +N
Sbjct: 999 TLPCKASGIPKPSIAWSKKG-ELIFTSSAKFSAGADGSLYVVSPGG-EESGEYVCTATNA 1056
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTP-------VTVSEGEFLQLSCHVRGSEPIRIQWL 1238
AG A + + +P VF P ++V GE + L C V+G P I W
Sbjct: 1057 AGYA--KRKVQLTVYVRPRVFGDQRGPSQDKPVEISVFAGEEVTLPCEVKGLPPPIITWA 1114
Query: 1239 KAGREIKP-SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXX 1415
K + I P S R +F + + E + +D+G Y+C A+N+AG+ T K+
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETR---VSDSGMYLCVATNIAGNVTQSVKLN----- 1166
Query: 1416 XXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGG 1595
V K+ + ++V ++ A+ G P+P + W KG GG
Sbjct: 1167 --------VHVPPKIQRGPKVMKVQVGQRVDIPCSAQ--GTPLPVITWFKG-------GG 1209
Query: 1596 RIFI----HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIE 1760
+ + H + + L I+ +D+G+Y CVA N G E+ + L V E E +E
Sbjct: 1210 AVLVDGLQHIRHPDGTLSIKQAVLSDAGIYTCVATNIAGSDETEITLHVQEPPILEDLE 1268
Score = 150 bits (378), Expect = 5e-36
Identities = 147/592 (24%), Positives = 224/592 (37%), Gaps = 6/592 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDS---NDS 182
+ + S L+C G P ++W K L + H R +V F ++ S D
Sbjct: 3724 IHLNKSTLLECFAEGVPAPRITWRKDGAVLSGS-----HARYSVLENGFLRIQSAQVTDG 3778
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y+C A ++ G L V +PPS + ++ TV + C +G SV
Sbjct: 3779 GRYLCMATSAAGTDRRRIDLQVH---VPPSIAPGPTNISVTVNVQTTLACEATGIPKPSV 3835
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+G L N + L + +L I Y CT TN G + L +
Sbjct: 3836 NWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNDAGEDKRAVDLTV-- 3893
Query: 543 GRNPPFFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDN-REIRSGGNYQISYLE 713
+ PP I P D +V + C +G + W K+ R + G Y+I
Sbjct: 3894 -QVPP--SIADEPTDFLVTKHTPTVITCTASGVPFPSIHWMKNGVRLLPRGEGYRIL--- 3947
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN 893
+S + IL G+YTC A N G L+++E PP + SE ++ N
Sbjct: 3948 SSGAIEILDTQLSHAGRYTCVARNSAGSAHRHVSLHVQE---PPVIQPQPSE-LDVILNN 4003
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
L G+ + W K + + + L Q+ +A DAG Y C
Sbjct: 4004 PILLPCEATGTPSPFIIWQKEGISVISSGRSHAVLPRGGL--QISRAVREDAGTYMCVAQ 4061
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
N AG+AL + ++ P PV H + + L C G P I W K G
Sbjct: 4062 NPAGTALGKIKLNVQVP---PVISPHPKEYITVVDKPIMLPCKADGLPPPDIMWHKDGHV 4118
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
I S R + L+ DAG Y C A+NVAGS ++ +K+T
Sbjct: 4119 IVESVRQRIL---SSGALQIAFAQPGDAGQYTCMAANVAGSSSTSTKLTVHVPPRIQSTE 4175
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
V+ E + A G P P + W K N G+ +
Sbjct: 4176 VHYTVN---------------ENSQAVLPCVADGIPTPAINWKKDNVPLANLLGKYTVEP 4220
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDL 1769
G+ L + + DSG Y C+A N GE ++L V+ ++ GD+
Sbjct: 4221 YGE---LILENVVLEDSGTYTCIANNAAGEDTHTISLTVHVLPTFTELPGDV 4269
Score = 148 bits (374), Expect = 2e-35
Identities = 150/572 (26%), Positives = 226/572 (39%), Gaps = 7/572 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V + + L C+ GTP + W K + ++ + H L ++ D+G Y
Sbjct: 3999 VILNNPILLPCEATGTPSPFIIWQKEGISV--ISSGRSHAVLPRGGLQISRAVREDAGTY 4056
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
+C A+N G L VQ +PP S ++ V P++ C G P + W
Sbjct: 4057 MCVAQNPAGTALGKIKLNVQ---VPPVISPHPKEYITVVDKPIMLPCKADGLPPPDIMWH 4113
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDG + + +++ L + A L I AGQY+C A N GS+S+S +L +
Sbjct: 4114 KDGHVIVE--SVRQRILSSGA-LQIAFAQPGDAGQYTCMAANVAGSSSTSTKLTV---HV 4167
Query: 552 PPFFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDNREIRSG-GNYQISYLENSA 722
PP I V V E++ C G + W KDN + + G Y + E
Sbjct: 4168 PP--RIQSTEVHYTVNENSQAVLPCVADGIPTPAINWKKDNVPLANLLGKYTV---EPYG 4222
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + V D+G YTC A N G+D+ T L + + P+FT+ L V +G R
Sbjct: 4223 ELILENVVLEDSGTYTCIANNAAGEDTHTISLTVH---VLPTFTE-LPGDVSLNKGEQLR 4278
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L + G + W NN I P + N L +++ S D+G Y C N
Sbjct: 4279 LNCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVIERISKEDSGTYVCTAENSV 4334
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSE-GEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
G + +KE PPVF + G L+C V+G IQW + G +I+
Sbjct: 4335 GFVKAIGFVYVKE---PPVFKGDYPSNWIEPLGGNAILNCEVKGDPAPTIQWSRRGIDIE 4391
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
S R NG+ L DAGDY C A+N AG +T
Sbjct: 4392 ISHRIR-QLGNGS--LAIYGTVNEDAGDYTCVATNEAGVVERSMSLT------------- 4435
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
+ EP + + + G+P P + W++ QG I ++
Sbjct: 4436 --LQSTPIITLEPVETIINAGSKVILNCQATGEPRPTITWSR-------QGHSILWDERI 4486
Query: 1620 D---EAKLEIRDTTKTDSGLYRCVAFNKHGEI 1706
+ L I K D+ Y CVA N G +
Sbjct: 4487 NVLSNNSLHIAAAQKEDTSEYECVARNLMGSV 4518
Score = 146 bits (369), Expect = 6e-35
Identities = 147/594 (24%), Positives = 228/594 (38%), Gaps = 19/594 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V + L+C+ G P ++WYK + ++ + + QV +DS
Sbjct: 1557 VSALINSIIKLECETRGLPMPAITWYKDGQPVISSSQALYVEKGQFLHIPRAQV--SDSA 1614
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDV---QETVGLPVVFECAVSGSEPI 356
Y C N G S + V +PP L + Q V + EC +G+ P
Sbjct: 1615 AYKCLVTNVAGTAEKSFHVDVY---VPPVIEGDLAEPLNKQVKVAHSLTLECKAAGNPPP 1671
Query: 357 SVSWFKDGRPLKDGPNIQ-TSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
++W KDG P+K NI+ + + + + DR GQY C AT+ G +
Sbjct: 1672 VLTWLKDGVPVKASDNIRIEAGGKKLEITSALEVDR---GQYICVATSVAGEKEIKYEVD 1728
Query: 534 L-----TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQ 698
+ EG + + I +V + +C VTG+ + W KD + I ++
Sbjct: 1729 VLVPPAIEGGDETSYFI------VMVNNLLELDCQVTGSPLPTIMWLKDGQLIDERDGFR 1782
Query: 699 ISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE 878
I L N L I + DTG Y C A N G ++ + +PP+
Sbjct: 1783 I--LLNGHKLVIAQAQVSDTGLYRCVATNTAGDHRKEFEVTVH---VPPTIKSSGLSERA 1837
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
+ L+ G S+ W K+ ++ TA + +++ LLQ+ KA M DAG Y
Sbjct: 1838 VLKYKPITLQCIANGIPNPSITWLKDGQPVN-TAQGNLKIQSSGRLLQIAKALMEDAGRY 1896
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFDQ--HLTPVTVSEGEFLQLSCHVRGSEPIRIQ 1232
TC +N AG T + +PP D + TV +QL C G+ I
Sbjct: 1897 TCVATNAAGE---TQQHIQLHVHEPPSLDDAGKMLNETVVVNSPVQLECKAAGTPSPAIT 1953
Query: 1233 WLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXX 1412
W K R + SD S +F N ++ + DAG Y C A N AG+
Sbjct: 1954 WYKDNRPL--SDSSSVTFLNRGQIINIESAQITDAGIYKCVAINSAGA------------ 1999
Query: 1413 XXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG-------- 1568
V +F + VV + G P P++ W K
Sbjct: 2000 -TELFYSLQVHVPPSIF--GSNNMVAVVVNNLVRLECEARGIPAPSLTWLKDGSPVTSFV 2056
Query: 1569 KWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
Q+ GGRI L + +D+G Y CVA N GE + +++L+V
Sbjct: 2057 NGIQVLSGGRI----------LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Score = 145 bits (366), Expect = 1e-34
Identities = 153/619 (24%), Positives = 245/619 (39%), Gaps = 14/619 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT G++A L C + ++W + D +R T T M N++ L V +D+G
Sbjct: 529 VTVTPGETAVLTCLVVSAVGYNLTWQRNDRDIRLTDTAGMRILANLS-LELRSVKFSDAG 587
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY C N G + + FLTVQE PP + ++ T G V C+ +G ++
Sbjct: 588 EYRCVVSNEGGSSTEAVFLTVQE---PPKVTVMPKNQSFTAGSEVSIMCSATGYPKPKIA 644
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W + + + + N+ N D AG Y C A+N G ++ L E
Sbjct: 645 WTMNDVFIMGSHRYRMTSEGNLFIKNAVPKD---AGIYGCLASNSAGMDKQTSTLRYIEA 701
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P + + + +G++ EC +G P +V W K + E++ ++L
Sbjct: 702 ---PKLIVVQSELLVALGDTTVMECKTSGVPPPQVKWFKGDLELKPS-----TFLITDPL 753
Query: 726 LTILKVDKG---DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
L +LK+ + D G YTC AVN+ G+ + L++ PP F ++ ++ E G++
Sbjct: 754 LGLLKIQETQDLDAGDYTCVAVNDAGRATGRITLDVGS---PPVFIQEPTDVSVEI-GSN 809
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALL----LQVKKASMGDAGLYTC 1064
L V G + W V+ P + + + + L L + D G Y C
Sbjct: 810 VTLPCYVQGYPEPKIKW--RRVDNMPIFSRPFSVSSISQLRTGDLFISNLWASDKGTYIC 867
Query: 1065 KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVT-VSEGEFLQLSCHVRGSEPI-RIQWL 1238
+ N G +++ + P + PVT V EG+ L L C + PI +W+
Sbjct: 868 EAENQFGKIQSQTTVTVTGLVAPLIGIS--PPVTSVIEGQQLTLPCALLAGNPIPERRWI 925
Query: 1239 KAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXX 1418
K + + + L + V D G+Y C ASNVAG + V
Sbjct: 926 KNSAMLVQN---PYITVRSDGSLHIERVRLQDGGEYTCVASNVAGITNKTTTVDVHVLPT 982
Query: 1419 XXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR 1598
Q + +E T K G P P++ W+K +G
Sbjct: 983 IQHG---------------QQILSTIEGIPVTLPCKASGIPKPSIAWSK-------KGEL 1020
Query: 1599 IFI----HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGD 1766
IF G + L + +SG Y C A N G + V L V R ++ GD
Sbjct: 1021 IFTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNAAGYAKRKVQLTVYVR---PRVFGD 1077
Query: 1767 LRAMLKKTPV-LKKGAGEE 1820
R + PV + AGEE
Sbjct: 1078 QRGPSQDKPVEISVFAGEE 1096
Score = 145 bits (365), Expect = 2e-34
Identities = 141/529 (26%), Positives = 220/529 (41%), Gaps = 5/529 (0%)
Frame = +3
Query: 162 QVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVS 341
+V D G Y C A ++ G + TF V E PP + +V T G V C V
Sbjct: 488 EVTLADEGAYECVAVSTAGIGRAQTFFDVSE---PPPVIQVPSNVTVTPGETAVLTCLVV 544
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
+ +++W ++ R ++ L N+ +L + S AG+Y C +N GS++ +
Sbjct: 545 SAVGYNLTWQRNDRDIRLTDTAGMRILANL-SLELRSVKFSDAGEYRCVVSNEGGSSTEA 603
Query: 522 ARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
L + E PP + G C TG K+AW ++ I Y++
Sbjct: 604 VFLTVQE---PPKVTVMPKNQSFTAGSEVSIMCSATGYPKPKIAWTMNDVFIMGSHRYRM 660
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
+ + +L I D G Y C A N G D T+ L E P SE +
Sbjct: 661 T---SEGNLFIKNAVPKDAGIYGCLASNSAGMDKQTSTLRYIE---APKLIVVQSELLVA 714
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNAL-LLQVKKASMGDAGLY 1058
G++ +E + +G P V W+K ++E+ P+ + L LL++++ DAG Y
Sbjct: 715 L-GDTTVMECKTSGVPPPQVKWFKGDLELKPST---FLITDPLLGLLKIQETQDLDAGDY 770
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWL 1238
TC NDAG A T I + + PPVF Q T V+V G + L C+V+G +I+W
Sbjct: 771 TCVAVNDAGRA--TGRITL-DVGSPPVFIQEPTDVSVEIGSNVTLPCYVQGYPEPKIKWR 827
Query: 1239 KAGREIKPSDRCSFSFAN----GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXX 1406
+ + P FS ++ T L ++ +D G Y+C+A N G S++ VT
Sbjct: 828 RV--DNMPIFSRPFSVSSISQLRTGDLFISNLWASDKGTYICEAENQFGKIQSQTTVT-- 883
Query: 1407 XXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLN 1586
+ L +S P + + + A + G+PIP +W K L
Sbjct: 884 ----------VTGLVAPLIGISPPVTSVIEGQQLTLPCALLAGNPIPERRWIKNS-AMLV 932
Query: 1587 QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
Q I + G L I D G Y CVA N G + V+
Sbjct: 933 QNPYITVRSDG---SLHIERVRLQDGGEYTCVASNVAGITNKTTTVDVH 978
Score = 145 bits (365), Expect = 2e-34
Identities = 138/571 (24%), Positives = 215/571 (37%), Gaps = 4/571 (0%)
Frame = +3
Query: 33 SLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENS 212
+L+C+ P ++W K +L+ AT ++ + L N D D+ Y C A N
Sbjct: 3640 TLECKSDAVPPPVITWLKNGERLQ--ATPRIRILSGGRYLQINNADLGDTANYTCVASNI 3697
Query: 213 VGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLK 392
G+ + LTV +PPS + + + + EC G ++W KDG L
Sbjct: 3698 AGKTTREFILTVN---VPPSIKSGPQSLVIHLNKSTLLECFAEGVPAPRITWRKDGAVLS 3754
Query: 393 DGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIP 572
G + + S L+N L I + G+Y C AT+ +A + R I + PP
Sbjct: 3755 -GSHARYSVLEN-GFLRIQSAQVTDGGRYLCMATS---AAGTDRRRIDLQVHVPPSIAPG 3809
Query: 573 LAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKG 752
+ V C TG V W K+ + N L +S L I+
Sbjct: 3810 PTNISVTVNVQTTLACEATGIPKPSVNWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVD 3869
Query: 753 DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQP 932
DT Y C N+ G+D L ++ +PPS + ++ + T+ + +G
Sbjct: 3870 DTATYECTVTNDAGEDKRAVDLTVQ---VPPSIADEPTDFL-VTKHTPTVITCTASGVPF 3925
Query: 933 ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIV 1112
S+ W KN V + P + A +++ + AG YTC N AGSA S+
Sbjct: 3926 PSIHWMKNGVRLLPRGEGYRILSSGA--IEILDTQLSHAGRYTCVARNSAGSAHRHVSLH 3983
Query: 1113 IKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFAN 1292
++E PPV + + V + L C G+ I W K G + S R
Sbjct: 3984 VQE---PPVIQPQPSELDVILNNPILLPCEATGTPSPFIIWQKEGISVISSGRSHAVLPR 4040
Query: 1293 GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVS 1472
G L+ + DAG Y+C A N AG+ K K+ V
Sbjct: 4041 GG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLN---------------VQVPPVISP 4083
Query: 1473 EPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG----DEAKLEI 1640
P+ V K G P P++ W K G + + L+I
Sbjct: 4084 HPKEYITVVDKPIMLPCKADGLPPPDIMWHK--------DGHVIVESVRQRILSSGALQI 4135
Query: 1641 RDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
D+G Y C+A N G ++ L V+
Sbjct: 4136 AFAQPGDAGQYTCMAANVAGSSSTSTKLTVH 4166
Score = 143 bits (361), Expect = 5e-34
Identities = 141/581 (24%), Positives = 225/581 (38%), Gaps = 8/581 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G SL C+ +G P + W K + + + ++ + L + + +D+G Y
Sbjct: 2208 VIEGHLISLLCESSGIPPPNLIWKKKGSPVLADSAGRVRILSGGRQLQISVAEKSDAGLY 2267
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A N G L V + + ++ T G V EC V G +V+W
Sbjct: 2268 SCMASNVAGTAKKDYSLQVYIRPTISNSGSHPTEIIVTRGKSVSLECEVEGVPQPAVTWM 2327
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDGRPL G ++ +D + + S G+Y C A N G + + L+
Sbjct: 2328 KDGRPLTKGRGME--IMDEGRVVQLKNVHVSDTGRYVCVAMNIAG--MTDRKYDLSVHTP 2383
Query: 552 PPFFDIPLAP--VDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P P + V S C +G + W KD + + +I L
Sbjct: 2384 PSIIGNHRTPENISVVEKSSVSLNCEASGIPLPSITWLKDGWPVNLSSSLRI--LSGGRI 2441
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-KKLSETVEETEGNSFR 902
L +++ D GQYTC N G++ +L++ L+PP + E V+ E S
Sbjct: 2442 LRLMQTRTEDAGQYTCVVRNAAGEERKIFRLSV---LVPPHIMGENTFEDVKVKEKQSVT 2498
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L V G+ + W+K+ + + + LQ+ A + G YTC SN A
Sbjct: 2499 LTCEVTGNPVPEITWHKDGQLLKEDDTHHL--MSGGRFLQIVNAQVSHTGRYTCLASNTA 2556
Query: 1083 GSALCTSSI-VIKEPKKPPV-FDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
G + S+ V+ P V D VTV L C P I W K G +
Sbjct: 2557 GDKSKSFSLNVLVSPIIAGVDGDGSPEDVTVILNSPTSLVCEAYSYPPATITWFKNGTPL 2616
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
+ + + G L+ + + DAG Y C A+N AG +V
Sbjct: 2617 ESNQ--NIRILPGGRTLQILNAQEDDAGRYACVATNEAGEMIKHYEVKVYIPPIIN---- 2670
Query: 1437 XXXVDGKLFFVS-EPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
G L P+ +++ T T + P ++ W K + L + I
Sbjct: 2671 ----KGDLLGPGLSPREVKIKVNNTLTLECEAYAIPSASLSWYK-DGQPLKSDDHVTIAA 2725
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHG--EIESNVNLQV 1730
G L+I++ +D+G Y CVA N G E++ +VN+QV
Sbjct: 2726 GGH--TLQIKEAQISDTGRYTCVASNVAGEDELDFDVNIQV 2764
Score = 128 bits (321), Expect = 2e-29
Identities = 140/579 (24%), Positives = 211/579 (36%), Gaps = 4/579 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ V V + L C +G P ++W K L + V + QV+ D+G
Sbjct: 3538 MSVIVNNPLELTCMASGIPAPKITWMKDGRPLPQMDQMQTLGGGEVLRISSTQVE--DTG 3595
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV--GLPVVFECAVSGSEPIS 359
Y C A + G+ + V +PP+ + TV V EC P
Sbjct: 3596 RYTCLASSPAGDDDKEYLVRVH---VPPNIAGTGEPQDFTVLRNRQVTLECKSDAVPPPV 3652
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
++W K+G L+ P I+ L L I D Y+C A+N G ++ ILT
Sbjct: 3653 ITWLKNGERLQATPRIR--ILSGGRYLQINNADLGDTANYTCVASNIAG--KTTREFILT 3708
Query: 540 EGRNPPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
P I P V+ +S EC G ++ W KD + SG + + S LE
Sbjct: 3709 VNVPP---SIKSGPQSLVIHLNKSTLLECFAEGVPAPRITWRKDG-AVLSGSHARYSVLE 3764
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN 893
N L I D G+Y C A + G D L + +PPS + T
Sbjct: 3765 N-GFLRIQSAQVTDGGRYLCMATSAAGTDRRRIDLQVH---VPPSIAPG-PTNISVTVNV 3819
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
L G SV W KN ++ N ++ L + S+ D Y C V+
Sbjct: 3820 QTTLACEATGIPKPSVNWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
NDAG + ++ P P + D+ T V++ ++C G I W+K G
Sbjct: 3880 NDAGEDKRAVDLTVQVP--PSIADEP-TDFLVTKHTPTVITCTASGVPFPSIHWMKNGVR 3936
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
+ P ++G +E D + AG Y C A N AGS
Sbjct: 3937 LLPRGEGYRILSSG--AIEILDTQLSHAGRYTCVARNSAGS---------------AHRH 3979
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
V +P + V+ + G P P + W K ++ G +
Sbjct: 3980 VSLHVQEPPVIQPQPSELDVILNNPILLPCEATGTPSPFIIWQKEGISVISSGRSHAVLP 4039
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+G L+I + D+G Y CVA N G + L V
Sbjct: 4040 RGG---LQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Score = 97.4 bits (241), Expect = 4e-20
Identities = 94/355 (26%), Positives = 143/355 (40%), Gaps = 3/355 (0%)
Frame = +3
Query: 675 IRSGGNYQIS-YLENSAHLT--ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPP 845
+R+G + YL+ SA +T I +V D G Y C AV+ G ++ E PP
Sbjct: 464 VRNGATLGVDQYLKESASVTWDIEEVTLADEGAYECVAVSTAGIGRAQTFFDVSE---PP 520
Query: 846 SFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQV 1025
+ + V T G + L V + ++ W +N+ +I T + N L L++
Sbjct: 521 PVIQ-VPSNVTVTPGETAVLTCLVVSAVGYNLTWQRNDRDIRLTDTAGMRILAN-LSLEL 578
Query: 1026 KKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHV 1205
+ DAG Y C VSN+ GS+ + ++EP K V ++ + + G + + C
Sbjct: 579 RSVKFSDAGEYRCVVSNEGGSSTEAVFLTVQEPPKVTVMPKN---QSFTAGSEVSIMCSA 635
Query: 1206 RGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTS 1385
G +I W I S R + L K+ DAG Y C ASN AG D
Sbjct: 636 TGYPKPKIAWTMNDVFIMGSHRYRMTSEGN---LFIKNAVPKDAGIYGCLASNSAGMDKQ 692
Query: 1386 KSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK 1565
S + ++ V + + + + TT K G P P VKW K
Sbjct: 693 TSTL--------------RYIEAPKLIVVQSELLVALGDTT-VMECKTSGVPPPQVKWFK 737
Query: 1566 GKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
G L F+ L+I++T D+G Y CVA N G + L V
Sbjct: 738 G---DLELKPSTFLITDPLLGLLKIQETQDLDAGDYTCVAVNDAGRATGRITLDV 789
Score = 92.8 bits (229), Expect = 1e-18
Identities = 78/268 (29%), Positives = 119/268 (44%), Gaps = 5/268 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFR--NNVATLVFNQVDSND 179
V + G+ L C+ G P ++W + + HF N + LV ++ D
Sbjct: 4269 VSLNKGEQLRLNCKATGIPLPKLTWTFNNNII------PAHFDSVNGHSELVIERISKED 4322
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQL-RDVQETVGLPVVFECAVSGSEPI 356
SG Y+C AENSVG V + F+ V+E PP F + E +G + C V G
Sbjct: 4323 SGTYVCTAENSVGFVKAIGFVYVKE---PPVFKGDYPSNWIEPLGGNAILNCEVKGDPAP 4379
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
++ W + G ++ I+ L N +L I+ T AG Y+C ATN G S L L
Sbjct: 4380 TIQWSRRGIDIEISHRIRQ--LGN-GSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTL 4436
Query: 537 TEGRNPPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
++ P I L PV+ ++ G C TG + W++ I + +I+ L
Sbjct: 4437 ---QSTPI--ITLEPVETIINAGSKVILNCQATGEPRPTITWSRQGHSIL--WDERINVL 4489
Query: 711 ENSAHLTILKVDKGDTGQYTCYAVNEVG 794
N++ L I K DT +Y C A N +G
Sbjct: 4490 SNNS-LHIAAAQKEDTSEYECVARNLMG 4516
>ref|XP_002685157.1| PREDICTED: Down syndrome cell adhesion molecule-like [Bos taurus].
Length = 1849
Score = 156 bits (394), Expect = 7e-38
Identities = 152/579 (26%), Positives = 235/579 (40%), Gaps = 15/579 (2%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
K G L C+ G PE W K + L + F+ + L+ +DSG
Sbjct: 72 KAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSG----RFQKTMTGLLIENTRPSDSGS 127
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y+C N G L V++ P + R V+ +VG V C+V+GSE +SW
Sbjct: 128 YVCEVSNRYGTAKVIGRLYVKQ---PLKATISPRKVKSSVGSQVSLSCSVTGSEDQELSW 184
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+++G L G N++ + + N L + RS G Y C SA +++L +G
Sbjct: 185 YRNGEILNPGKNVRITGI-NHENLIMDHMVRSDGGAYQCFVRKDRLSAQDFVQVVLEDGT 243
Query: 549 N---PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
F + ++P +AV C+V GT + W D+ I GG+++IS + S
Sbjct: 244 PKIISAFSEKVVSPAEAV-----SLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITS 298
Query: 720 -----AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
++L I D G Y C A N G A++N++ P S + + +
Sbjct: 299 EGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG---PASI--RPMKNITAI 353
Query: 885 EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTC 1064
G + RV G S+ WYKN+ + P + ++ F+NN L D G YTC
Sbjct: 354 AGRDTYIHCRVIGYPYYSIKWYKNS-NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC 412
Query: 1065 KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSC-HVRGSEPIRIQWLK 1241
V L TS V K PP F Q S G+ + + C V G PI I W K
Sbjct: 413 NVL--VQPQLSTSQSVHVTVKVPP-FIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQK 469
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
GR I S + + T+ L +++ G+Y C A N A + +S++
Sbjct: 470 DGRPIPASLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPK- 528
Query: 1422 XXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW--TKG----KWRQL 1583
FV +P+ + G P+P + W +KG +++ +
Sbjct: 529 --------------FVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPI 574
Query: 1584 NQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG 1700
GRI + G L I+ + DSG Y C N G
Sbjct: 575 ALNGRIQVLSNG---SLLIKHVVEEDSGYYLCKVSNDVG 610
Score = 133 bits (335), Expect = 5e-31
Identities = 148/612 (24%), Positives = 248/612 (40%), Gaps = 27/612 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK +VG SL C + G+ + +SWY+ L P ++ N+ L+ + + +D G
Sbjct: 160 VKSSVGSQVSLSCSVTGSEDQELSWYRNGEILNPGKNVRITGINH-ENLIMDHMVRSDGG 218
Query: 186 EYICRAENSVGEVSSSTFLTVQEQ----KLPPSFSRQLRDVQETVGLPVVFECAVSGSEP 353
Y C +S+ F+ V + K+ +FS ++ E V L C V G+
Sbjct: 219 AYQCFVRKD--RLSAQDFVQVVLEDGTPKIISAFSEKVVSPAEAVSLM----CNVKGTPL 272
Query: 354 ISVSWFKDGRPLKDGPNIQTSFL-----DNVATLNIFQTDRSFAGQYSCTATNPIGSASS 518
+++W D P+ G + + S + + V+ LNI + G Y CTA N G
Sbjct: 273 PTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLY 332
Query: 519 SARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQ 698
AR+ + R P P+ + A+ G C V G + W K N + + Q
Sbjct: 333 QARINV---RGPASIR-PMKNITAIAGRDTYIHCRVIGYPYYSIKWYK-NSNLLPFNHRQ 387
Query: 699 ISYLENSAHLTILKVDKG-DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETV 875
+++ EN+ L + V K D G+YTC + + QL+ + + T K+ +
Sbjct: 388 VAF-ENNGTLKLSDVQKEVDEGEYTCNVLVQ-------PQLSTSQSV---HVTVKVPPFI 436
Query: 876 EETEGNSFRLEGRV-------AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKA 1034
+ E F + RV +G PI++ W K+ I + I + L++
Sbjct: 437 QPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPASLGVTIDNIDFTSSLRISNL 496
Query: 1035 SMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGS 1214
S+ G YTC N+A + S ++++ P K V + + G+ + L+C G
Sbjct: 497 SLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIY---GKAVILNCSAEGY 553
Query: 1215 EPIRIQW-LKAGREIKPSDRCSFS-----FANGTAVLEFKDVTKADAGDYVCKASNVAGS 1376
I W G + + + +NG+ ++ K V + D+G Y+CK SN G+
Sbjct: 554 PVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLI--KHVVEEDSGYYLCKVSNDVGA 611
Query: 1377 DTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVK 1556
D SKS V S P + + G+ V+
Sbjct: 612 DVSKS--------------MYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVR 657
Query: 1557 WTKGKWRQLNQGGRIFIHQK--GDE--AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNL 1724
W K + R + K G+E + L+I T + DSG + C A N +GE + L
Sbjct: 658 WEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQL 717
Query: 1725 QVNERKKQEKIE 1760
V E +IE
Sbjct: 718 TVQEPPDPPEIE 729
Score = 79.3 bits (194), Expect = 1e-14
Identities = 72/297 (24%), Positives = 123/297 (41%), Gaps = 13/297 (4%)
Frame = +3
Query: 9 KVTVGDSASLQCQL-AGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ ++G + C + +G I ++W K + + + + ++L + + +G
Sbjct: 443 RFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPASLGVTIDNIDFTSSLRISNLSLMHNG 502
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C A N V + L V ++PP F Q RD G V+ C+ G ++
Sbjct: 503 NYTCIARNEAAAVEHQSQLIV---RVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIV 559
Query: 366 W-FKDG------RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
W F G +P+ IQ ++ ++ + D +G Y C +N +G A S
Sbjct: 560 WKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEED---SGYYLCKVSNDVG-ADVSK 615
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSG-GNYQI 701
+ LT P + A G+ + C G +PI V W K++R I Y +
Sbjct: 616 SMYLTVKIPAMITSYPNTTL-ATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLV 674
Query: 702 SYLENSAH----LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKK 860
S E L IL + D+G ++C+A+N G+D QL ++E PP K
Sbjct: 675 STKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIK 731
>ref|NP_001179817.2| roundabout homolog 1 [Bos taurus].
Length = 1653
Score = 155 bits (392), Expect = 1e-37
Identities = 136/473 (28%), Positives = 194/473 (41%), Gaps = 16/473 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKG----DTKLRPTATYKMHFRNN---VATLVFNQVD 170
V+ G+ A+L C+ G P + WYKG +T +++M + +V +
Sbjct: 79 VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 138
Query: 171 SNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
D G Y+C A N +GE S +++ L F + DV VG P V EC
Sbjct: 139 RPDEGVYVCVARNYLGEAVSHN-ASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGH 197
Query: 351 P-ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSAR 527
P ++SW KDG PL D T L I T +S AG+Y C TN +G S
Sbjct: 198 PEPTISWKKDGSPLDDKDERITI---RGGKLMITYTRKSDAGKYVCVGTNMVGERESEV- 253
Query: 528 LILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISY 707
LT P F P + + V +SA+F+C G V W KD+ E+ Y+I
Sbjct: 254 AELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRYEI-- 309
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
+ L I KV GD G YTC A N VGK +A L ++ PP F K + V
Sbjct: 310 -RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVAL- 367
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVE-----IHPTANCEITFKNNALLLQVKKASMGDAG 1052
G + + G+ ++ W + + P + + L + D G
Sbjct: 368 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVG 427
Query: 1053 LYTCKVSNDAGSALCTSSIVIKE---PKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
Y C+ N AGS + + + + + + PPV Q TV+ L LSC GS
Sbjct: 428 YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLVLSCVATGSPVP 487
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
I W K G + D G VL+ + D G Y C AS +G T
Sbjct: 488 TILWRKDGVLVSTQDSRIKQLETG--VLQIRYAKLGDTGRYTCIASTPSGEAT 538
Score = 135 bits (341), Expect = 1e-31
Identities = 136/536 (25%), Positives = 215/536 (40%), Gaps = 25/536 (4%)
Frame = +3
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGR 383
+NS+G S ++++ PP D+ + G P C G ++ W+K G
Sbjct: 51 DNSLGYTGSR----LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGE 106
Query: 384 PL---KDGPNIQTSFLDNVATLNIF----QTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+ KD P L + + + + R G Y C A N +G A S +
Sbjct: 107 RVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVA 166
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIK-VAWAKDNREIRS--------GGNY 695
F P + V VGE A EC P ++W KD + GG
Sbjct: 167 ILRDDFRQNP-SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKL 225
Query: 696 QISYLENSAHLTILKVDKGDTGQYTCYAVNEVG-KDSCTAQLNIKERLIPPSFTKKLSE- 869
I+Y K D G+Y C N VG ++S A+L + ER PSF K+ S
Sbjct: 226 MITYTR-----------KSDAGKYVCVGTNMVGERESEVAELTVLER---PSFVKRPSNL 271
Query: 870 TVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDA 1049
V + F+ E R G +V W K++ E+ P + EI + L+++K + GD
Sbjct: 272 AVTVDDSAEFKCEAR--GDPVPTVRWRKDDGEL-PKSRYEIRDDHT---LKIRKVTAGDM 325
Query: 1050 GLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRI 1229
G YTC N G A ++++ ++ +PP F V+ G + C G+ I
Sbjct: 326 GSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAI 385
Query: 1230 QWLKAGRE-----IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS- 1391
W + G + +P S + T L +V ++D G Y+C+ NVAGS +K+
Sbjct: 386 FWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAY 445
Query: 1392 -KVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG 1568
+VT V+ Q++ V + +A G P+P + W K
Sbjct: 446 LEVTDVIADRPPPVIRQGPVN---------QTVAVDGTLVLSCVAT--GSPVPTILWRKD 494
Query: 1569 KWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
Q RI ++ + L+IR D+G Y C+A GE + ++V E
Sbjct: 495 GVLVSTQDSRI---KQLETGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQE 547
Score = 115 bits (287), Expect = 2e-25
Identities = 91/287 (31%), Positives = 130/287 (45%), Gaps = 10/287 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VTV DSA +C+ G P V W K D +L P + Y++ + TL +V + D G Y
Sbjct: 273 VTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDDH---TLKIRKVTAGDMGSY 328
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C AEN VG+ +S LTVQ PP F + RD +G V F+C +G+ ++ W
Sbjct: 329 TCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR 388
Query: 372 KDGRP----LKDGPNIQTSF-LDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
++G P + F + L I RS G Y C N GS + A L +
Sbjct: 389 REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV 448
Query: 537 TE---GRNPPFFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
T+ R PP I PV+ V C TG+ + W KD + S + +I
Sbjct: 449 TDVIADRPPPV--IRQGPVNQTVAVDGTLVLSCVATGSPVPTILWRKDG-VLVSTQDSRI 505
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP 842
LE L I GDTG+YTC A G+ + +A + ++E +P
Sbjct: 506 KQLETGV-LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVP 551
>ref|XP_002684697.1| PREDICTED: roundabout, axon guidance receptor, homolog 1 (Drosophila)
[Bos taurus].
Length = 1650
Score = 155 bits (392), Expect = 1e-37
Identities = 137/473 (28%), Positives = 195/473 (41%), Gaps = 16/473 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKG----DTKLRPTATYKMHFRNN---VATLVFNQVD 170
V+ G+ A+L C+ G P + WYKG +T +++M + +V +
Sbjct: 79 VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 138
Query: 171 SNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
D G Y+C A N +GE S +++ L F + DV VG P V EC
Sbjct: 139 RPDEGVYVCVARNYLGEAVSHN-ASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGH 197
Query: 351 P-ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSAR 527
P ++SW KDG PL D T L I T +S AG+Y C TN +G S
Sbjct: 198 PEPTISWKKDGSPLDDKDERITI---RGGKLMITYTRKSDAGKYVCVGTNMVGERESEV- 253
Query: 528 LILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISY 707
LT P F P + + V +SA+F+C G V W KD+ E+ Y+I
Sbjct: 254 AELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRYEI-- 309
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
+ L I KV GD G YTC A N VGK +A L ++E PP F K + V
Sbjct: 310 -RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQE---PPHFVVKPRDQVVAL- 364
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVE-----IHPTANCEITFKNNALLLQVKKASMGDAG 1052
G + + G+ ++ W + + P + + L + D G
Sbjct: 365 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVG 424
Query: 1053 LYTCKVSNDAGSALCTSSIVIKE---PKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
Y C+ N AGS + + + + + + PPV Q TV+ L LSC GS
Sbjct: 425 YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLVLSCVATGSPVP 484
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
I W K G + D G VL+ + D G Y C AS +G T
Sbjct: 485 TILWRKDGVLVSTQDSRIKQLETG--VLQIRYAKLGDTGRYTCIASTPSGEAT 535
Score = 133 bits (335), Expect = 5e-31
Identities = 137/536 (25%), Positives = 215/536 (40%), Gaps = 25/536 (4%)
Frame = +3
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGR 383
+NS+G S ++++ PP D+ + G P C G ++ W+K G
Sbjct: 51 DNSLGYTGSR----LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGE 106
Query: 384 PL---KDGPNIQTSFLDNVATLNIF----QTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+ KD P L + + + + R G Y C A N +G A S +
Sbjct: 107 RVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVA 166
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIK-VAWAKDNREIRS--------GGNY 695
F P + V VGE A EC P ++W KD + GG
Sbjct: 167 ILRDDFRQNP-SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKL 225
Query: 696 QISYLENSAHLTILKVDKGDTGQYTCYAVNEVG-KDSCTAQLNIKERLIPPSFTKKLSE- 869
I+Y K D G+Y C N VG ++S A+L + ER PSF K+ S
Sbjct: 226 MITYTR-----------KSDAGKYVCVGTNMVGERESEVAELTVLER---PSFVKRPSNL 271
Query: 870 TVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDA 1049
V + F+ E R G +V W K++ E+ P + EI + L+++K + GD
Sbjct: 272 AVTVDDSAEFKCEAR--GDPVPTVRWRKDDGEL-PKSRYEIRDDHT---LKIRKVTAGDM 325
Query: 1050 GLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRI 1229
G YTC N G A ++++ ++E PP F V+ G + C G+ I
Sbjct: 326 GSYTCVAENMVGKAEASATLTVQE---PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAI 382
Query: 1230 QWLKAGRE-----IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS- 1391
W + G + +P S + T L +V ++D G Y+C+ NVAGS +K+
Sbjct: 383 FWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAY 442
Query: 1392 -KVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG 1568
+VT V+ Q++ V + +A G P+P + W K
Sbjct: 443 LEVTDVIADRPPPVIRQGPVN---------QTVAVDGTLVLSCVAT--GSPVPTILWRKD 491
Query: 1569 KWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
Q RI ++ + L+IR D+G Y C+A GE + ++V E
Sbjct: 492 GVLVSTQDSRI---KQLETGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQE 544
Score = 114 bits (285), Expect = 3e-25
Identities = 92/287 (32%), Positives = 131/287 (45%), Gaps = 10/287 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VTV DSA +C+ G P V W K D +L P + Y++ + TL +V + D G Y
Sbjct: 273 VTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDDH---TLKIRKVTAGDMGSY 328
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C AEN VG+ +S LTVQE PP F + RD +G V F+C +G+ ++ W
Sbjct: 329 TCVAENMVGKAEASATLTVQE---PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR 385
Query: 372 KDGRP----LKDGPNIQTSF-LDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
++G P + F + L I RS G Y C N GS + A L +
Sbjct: 386 REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV 445
Query: 537 TE---GRNPPFFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
T+ R PP I PV+ V C TG+ + W KD + S + +I
Sbjct: 446 TDVIADRPPPV--IRQGPVNQTVAVDGTLVLSCVATGSPVPTILWRKDG-VLVSTQDSRI 502
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP 842
LE L I GDTG+YTC A G+ + +A + ++E +P
Sbjct: 503 KQLETGV-LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVP 548
>ref|XP_614756.4| PREDICTED: roundabout 1 [Bos taurus].
Length = 1511
Score = 154 bits (388), Expect = 4e-37
Identities = 143/517 (27%), Positives = 218/517 (42%), Gaps = 20/517 (3%)
Frame = +3
Query: 246 VQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPL---KDGPNIQTS 416
++++ PP DV + G P C G ++ W+KDG + KD P
Sbjct: 11 LRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRM 70
Query: 417 FL--DNVATLNIFQTDRS--FAGQYSCTATNPIGSA-SSSARLILTEGRNPPFFDIPLAP 581
L ++ L I RS G Y C A N +G A S +A L + R+ D P
Sbjct: 71 LLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRD----DFRQNP 126
Query: 582 VDAVV--GESADFECHVTGTQP-IKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKG 752
D VV GE A EC P + W KD I +IS L I K
Sbjct: 127 TDVVVAAGEPAILECQPPRGHPEPTIYWKKDKIRI-DDKEERISI--RGGKLMISNTRKS 183
Query: 753 DTGQYTCYAVNEVG-KDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQ 929
D G YTC N VG +DS A+L + ER P + +++ V E E FR + V G
Sbjct: 184 DAGMYTCVGTNMVGERDSDPAELTVFER--PTFLRRPINQVVLEEEAVEFRCQ--VQGDP 239
Query: 930 PISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSI 1109
+V W K++ ++ P +I + L++KKA D G Y C N G ++++
Sbjct: 240 QPTVRWKKDDADL-PRGRYDI---KDDYTLRIKKAMSTDEGTYMCIAENRVGKVEASATL 295
Query: 1110 VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE--------IKPS 1265
+ + PP F V++G + C +G+ + W K G + +P+
Sbjct: 296 TV---RAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPN 352
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
RCS S T L ++ ++DAG Y+C+A VAGS +K+++
Sbjct: 353 SRCSVS---PTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPP---- 405
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
+ P + + TA K GDP+P + W K + L + R I ++G
Sbjct: 406 -----IILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFLGRDPRATIQEQG-- 458
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
L+I++ +D+G Y CVA + GE + L V E
Sbjct: 459 -TLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTE 494
Score = 135 bits (341), Expect = 1e-31
Identities = 125/482 (25%), Positives = 197/482 (40%), Gaps = 18/482 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKG----DTKLRPTATYKMHFRNN---VATLVFNQ 164
V V+ G+ +L C+ G P + WYK +T +++M + +V +
Sbjct: 27 VIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 86
Query: 165 VDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSG 344
D G Y+C A N +GE S +++ L F + DV G P + EC
Sbjct: 87 RSKPDEGSYVCVARNYLGEAVSRN-ASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPR 145
Query: 345 SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
P ++K + D + S L I T +S AG Y+C TN +G S
Sbjct: 146 GHPEPTIYWKKDKIRIDDKEERISI--RGGKLMISNTRKSDAGMYTCVGTNMVGERDSDP 203
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
LT P F P+ V + E+ +F C V G V W KD+ ++ G Y I
Sbjct: 204 -AELTVFERPTFLRRPINQV-VLEEEAVEFRCQVQGDPQPTVRWKKDDADL-PRGRYDI- 259
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
++ L I K D G Y C A N VGK +A L ++ PP F + + +
Sbjct: 260 --KDDYTLRIKKAMSTDEGTYMCIAENRVGKVEASATLTVR---APPQFVVRPRDQI-VA 313
Query: 885 EGNSFRLEGRVAGSQPISVAWYKN--------NVEIHPTANCEITFKNNALLLQVKKASM 1040
+G + G+ +V W K N P + C ++ + + ++++
Sbjct: 314 QGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRS-- 371
Query: 1041 GDAGLYTCKVSNDAGSALCTSSIVIKE---PKKPPVFDQHLTPVTVSEGEFLQLSCHVRG 1211
DAG Y C+ AGS L + + + + + PP+ Q T++ L C G
Sbjct: 372 -DAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATG 430
Query: 1212 SEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS 1391
I WLK G D + GT L+ K++ +D G Y C A++ +G +TS S
Sbjct: 431 DPLPVISWLKEGFTFLGRDPRATIQEQGT--LQIKNLRISDTGTYTCVATSSSG-ETSWS 487
Query: 1392 KV 1397
V
Sbjct: 488 AV 489
Score = 103 bits (257), Expect = 6e-22
Identities = 85/278 (30%), Positives = 121/278 (43%), Gaps = 9/278 (3%)
Frame = +3
Query: 24 DSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRA 203
++ +CQ+ G P+ V W K D L P Y + + TL + S D G Y+C A
Sbjct: 227 EAVEFRCQVQGDPQPTVRWKKDDADL-PRGRYDI---KDDYTLRIKKAMSTDEGTYMCIA 282
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGR 383
EN VG+V +S LTV + PP F + RD G V F C G+ +V W K+G
Sbjct: 283 ENRVGKVEASATLTV---RAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGS 339
Query: 384 P------LKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE- 542
PN + S + L I RS AG Y C A GS + A+L +T+
Sbjct: 340 QNLLFPNQPQQPNSRCS-VSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDV 398
Query: 543 --GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
R PP A V +A +C TG ++W K+ G + ++
Sbjct: 399 LTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFL--GRDPRATIQE 456
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKE 830
L I + DTG YTC A + G+ S +A L++ E
Sbjct: 457 QGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTE 494
>ref|XP_002699249.1| PREDICTED: roundabout 1-like [Bos taurus].
Length = 1394
Score = 150 bits (379), Expect = 4e-36
Identities = 129/474 (27%), Positives = 204/474 (43%), Gaps = 20/474 (4%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVAT-------LVFNQVD 170
V+ G+ A+L C+ G P + WYK ++ R + + +V +
Sbjct: 75 VSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGALFFPRIVHGRRA 134
Query: 171 SNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
D G Y C A N +G +S +++ L F + +V VG P V EC
Sbjct: 135 RPDEGVYTCVARNYLGAAASRN-ASLEVAVLRDDFRQSPGNVVVAVGEPAVMECMPPRGH 193
Query: 351 PI-SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASS-SA 524
P SVSW KDG LK+ T + + F++D AG Y C A+N G S +A
Sbjct: 194 PEPSVSWKKDGVRLKEEEGRITIRGGKLMMSHTFKSD---AGMYVCVASNMAGERESGAA 250
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
+L++ E P F P+ V + G DF C V G P ++ W K++ E+ +G Y+I
Sbjct: 251 KLVVLE--RPSFLRRPVNQV-VLAGAPVDFPCEVQGDPPPRLRWRKEDGELPTG-RYEI- 305
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
++ L I +V D G YTC A N VG+ + L + +PP + + +
Sbjct: 306 --QSDHSLQIGRVSAEDEGTYTCVAENSVGRAEASGSLIVH---VPPQLVTQPQDQMA-A 359
Query: 885 EGNSFRLEGRVAGSQPISVAWYKNNVE--------IHPTANCEITFKNNALLLQVKKASM 1040
G+S + G+ P ++ W K + + PT ++ + L + +
Sbjct: 360 PGDSVAFQCETKGNPPPAIFWQKEGSQALLFPSQSLQPTGRFSVSPRGQ---LNITEVQS 416
Query: 1041 GDAGLYTCKVSNDAGSALCTSSIVIKEPKK---PPVFDQHLTPVTVSEGEFLQLSCHVRG 1211
DAG Y C+ + AGS L + + +K PP+ Q T++ G + L C V G
Sbjct: 417 RDAGYYVCQAVSVAGSVLAKALLEVKGASLEGLPPIILQGPANQTLALGSSVWLPCRVSG 476
Query: 1212 SEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAG 1373
+ +QW K G+ ++ D ANGT L V + G Y C A + G
Sbjct: 477 NPQPSVQWKKDGQWLQGDDVQLSVMANGT--LYIASVQEGHMGFYSCVAKSSTG 528
Score = 118 bits (295), Expect = 2e-26
Identities = 130/499 (26%), Positives = 203/499 (40%), Gaps = 20/499 (4%)
Frame = +3
Query: 267 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPL---KDGPNIQTSFLDNVAT 437
P Q D+ + G P C G ++ W+K+G + ++ P L + A
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGAL 123
Query: 438 ----LNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGES 605
+ + R G Y+C A N +G+A+S + F P V VGE
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSP-GNVVVAVGEP 182
Query: 606 ADFECHVTGTQPI-KVAWAKDNREIRSG-GNYQISYLENSAHLTILKVDKGDTGQYTCYA 779
A EC P V+W KD ++ G I L + K D G Y C A
Sbjct: 183 AVMECMPPRGHPEPSVSWKKDGVRLKEEEGRITI----RGGKLMMSHTFKSDAGMYVCVA 238
Query: 780 VNEVG-KDSCTAQLNIKERLIPPSFTKK-LSETVEETEGNSFRLEGRVAGSQPISVAWYK 953
N G ++S A+L + ER PSF ++ +++ V F E V G P + W K
Sbjct: 239 SNMAGERESGAAKLVVLER---PSFLRRPVNQVVLAGAPVDFPCE--VQGDPPPRLRWRK 293
Query: 954 NNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKP 1133
+ E+ PT EI ++ LQ+ + S D G YTC N G A + S+++ P P
Sbjct: 294 EDGEL-PTGRYEIQSDHS---LQIGRVSAEDEGTYTCVAENSVGRAEASGSLIVHVP--P 347
Query: 1134 PVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE--------IKPSDRCSFSFA 1289
+ Q + + G+ + C +G+ P I W K G + ++P+ R S S
Sbjct: 348 QLVTQPQDQMA-APGDSVAFQCETKGNPPPAIFWQKEGSQALLFPSQSLQPTGRFSVS-- 404
Query: 1290 NGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFV 1469
L +V DAG YVC+A +VAGS +K+ + +
Sbjct: 405 -PRGQLNITEVQSRDAGYYVCQAVSVAGSVLAKALLEVKGASLEGLPP---------IIL 454
Query: 1470 SEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQLNQGGRIFIHQKGDEAKLEIRD 1646
P + + ++ +V G+P P+V+W K G+W Q ++ + G L I
Sbjct: 455 QGPANQTLALGSSVWLPCRVSGNPQPSVQWKKDGQWLQ-GDDVQLSVMANG---TLYIAS 510
Query: 1647 TTKTDSGLYRCVAFNKHGE 1703
+ G Y CVA + GE
Sbjct: 511 VQEGHMGFYSCVAKSSTGE 529
Score = 74.3 bits (181), Expect = 4e-13
Identities = 110/457 (24%), Positives = 166/457 (36%), Gaps = 31/457 (6%)
Frame = +3
Query: 453 TDRSFAGQYSCTATN----PIGSASSSARLILTEGRNPPFFDIPLAPVDAVV--GESADF 614
+D F S A N P G S + I E P + P D +V GE A
Sbjct: 27 SDLLFGFNSSVAALNQSLLPPGDPSLNGSRIGPEDAMPRIVE---QPPDLLVSRGEPATL 83
Query: 615 ECHVTGTQPIKVAWAKDNREIRSGGNYQISY--LENSAHLTILKVDKG-----DTGQYTC 773
C G + W K+ + + ++ L S L ++ G D G YTC
Sbjct: 84 PCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGALFFPRIVHGRRARPDEGVYTC 143
Query: 774 YAVNEVGKD-SCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA--------GS 926
A N +G S A L + L + ++ GN G A G
Sbjct: 144 VARNYLGAAASRNASLEVAV----------LRDDFRQSPGNVVVAVGEPAVMECMPPRGH 193
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC-TS 1103
SV+W K+ V + IT + L++ S DAG+Y C SN AG +
Sbjct: 194 PEPSVSWKKDGVRLKEEEG-RITIRGGKLMMSHTFKS--DAGMYVCVASNMAGERESGAA 250
Query: 1104 SIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFS 1283
+V+ E P F + V G + C V+G P R++W K E+ P+ R
Sbjct: 251 KLVVLER---PSFLRRPVNQVVLAGAPVDFPCEVQGDPPPRLRWRKEDGEL-PTGRYEIQ 306
Query: 1284 FANGTAVLEFKDVTKADAGDYVCKASNVAG-SDTSKSKVTXXXXXXXXXXXXXXXVDGKL 1460
+ L+ V+ D G Y C A N G ++ S S +
Sbjct: 307 SDHS---LQIGRVSAEDEGTYTCVAENSVGRAEASGSLIVHVPPQ--------------- 348
Query: 1461 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG-------KWRQLNQGGRIFIHQKG 1619
V++PQ + F + G+P P + W K + L GR + +G
Sbjct: 349 -LVTQPQDQMAAPGDSVAFQCETKGNPPPAIFWQKEGSQALLFPSQSLQPTGRFSVSPRG 407
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+L I + D+G Y C A + G + + L+V
Sbjct: 408 ---QLNITEVQSRDAGYYVCQAVSVAGSVLAKALLEV 441
Score = 63.9 bits (154), Expect = 5e-10
Identities = 75/293 (25%), Positives = 116/293 (39%), Gaps = 9/293 (3%)
Frame = +3
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEI-----HPTANCEITFKNNALL---LQVKKAS 1037
+ G L R G ++ WYKN + P A+ + + AL + + +
Sbjct: 76 SRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAH-RLLLPSGALFFPRIVHGRRA 134
Query: 1038 MGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHV-RGS 1214
D G+YTC N G+A ++ + + F Q V V+ GE + C RG
Sbjct: 135 RPDEGVYTCVARNYLGAAASRNASLEVAVLRDD-FRQSPGNVVVAVGEPAVMECMPPRGH 193
Query: 1215 EPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSK 1394
+ W K G +K + + G ++ K+DAG YVC ASN+AG S +
Sbjct: 194 PEPSVSWKKDGVRLKEEEG-RITIRGGKLMMSH--TFKSDAGMYVCVASNMAGERESGAA 250
Query: 1395 VTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKW 1574
V + F+ P + V+ F +V GDP P ++W K
Sbjct: 251 --------------KLVVLERPSFLRRPVNQVVLAGAPVDFPCEVQGDPPPRLRWRKEDG 296
Query: 1575 RQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
GR I + L+I + D G Y CVA N G E++ +L V+
Sbjct: 297 ELPT--GRYEIQS---DHSLQIGRVSAEDEGTYTCVAENSVGRAEASGSLIVH 344
>ref|XP_002693048.1| PREDICTED: Down syndrome cell adhesion molecule like 1 [Bos taurus].
Length = 2112
Score = 146 bits (369), Expect = 6e-35
Identities = 144/577 (24%), Positives = 224/577 (38%), Gaps = 13/577 (2%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+V G + L C +G P + W K L + + + L + + + DSG
Sbjct: 295 EVWAGHTMELPCTASGYPIPAIRWLKDGRPLPADSRWT----KRITGLTISDLRTEDSGT 350
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
YIC N+ G + LTV + P + ++++ +G V+ CA+ GS ++ W
Sbjct: 351 YICEVTNTFGSAEVTGTLTVID---PLHVTLTPKNLKTGIGSTVILSCALLGSPEFTIRW 407
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+++ + I L N TL I +S +G Y C AT +A A ++L +G
Sbjct: 408 YRNTELVLPSEAISIRGLSN-ETLLITSAQKSHSGAYQCFATRKTQTAQDFAIIVLEDG- 465
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS--- 719
P + GE C G P + WA D+ I G+++ + S
Sbjct: 466 -TPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTITWALDDEPIVRDGSHRTNQYTMSDGT 524
Query: 720 --AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN 893
+H+ + D G Y C A N VG A++N++ PPS + + G
Sbjct: 525 TISHMNVTGPQIRDGGVYRCTARNSVGSAEYQARINVRG---PPSI--RAMRNITAVAGR 579
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
+ RV G S+ WYK+ + + P + ++ F+N L L + M D G Y C V
Sbjct: 580 DTLVNCRVIGYPYYSIKWYKDAL-LLPDNHRQVVFENGTLKLTDVQKGM-DEGEYLCSVL 637
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHV-RGSEPIRIQWLKAGR 1250
L S V K PP+ P S G+ L + C V G PIRI W K G+
Sbjct: 638 --IQPQLSISQSVHVAVKVPPLIQPFEFP-PASIGQLLYIPCVVSSGDMPIRITWRKDGQ 694
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
I + + L+ V+ G+Y C ASN A + + + ++
Sbjct: 695 VIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPR---- 750
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGK-------WRQLNQ 1589
FV +P + + V G P P V W K + +
Sbjct: 751 -----------FVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPL 799
Query: 1590 GGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG 1700
GRI Q + L IR + D G Y C A N G
Sbjct: 800 TGRI---QILPNSSLLIRHVLEEDIGYYLCQASNGVG 833
Score = 136 bits (343), Expect = 6e-32
Identities = 143/611 (23%), Positives = 236/611 (38%), Gaps = 26/611 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+K +G + L C L G+PE + WY+ + P+ + +N TL+ + SG
Sbjct: 383 LKTGIGSTVILSCALLGSPEFTIRWYRNTELVLPSEAISIRGLSN-ETLLITSAQKSHSG 441
Query: 186 EYICRAENSVGEVSSSTFLTVQE--QKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C A + +++ ++ SFS ++ + E L CA G+ P +
Sbjct: 442 AYQCFATRKTQTAQDFAIIVLEDGTPRIVSSFSEKVVNPGEQFSL----MCAAKGAPPPT 497
Query: 360 VSWFKDGRPL-KDGPNIQTSFL----DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
++W D P+ +DG + + ++ +N+ G Y CTA N +GSA A
Sbjct: 498 ITWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNSVGSAEYQA 557
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
R+ + R PP + + AV G C V G + W KD + N++
Sbjct: 558 RINV---RGPPSIR-AMRNITAVAGRDTLVNCRVIGYPYYSIKWYKD--ALLLPDNHRQV 611
Query: 705 YLENSAHLTILKVDKG-DTGQYTCYAVNEVGKDSCTAQLNIKERL-----IPPSFTKKLS 866
EN L + V KG D G+Y C + + QL+I + + +PP +
Sbjct: 612 VFENGT-LKLTDVQKGMDEGEYLCSVLIQ-------PQLSISQSVHVAVKVPPLI--QPF 661
Query: 867 ETVEETEGNSFRLEGRV-AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMG 1043
E + G + V +G PI + W K+ I + I K LQ+ S+
Sbjct: 662 EFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLK 721
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
G YTC SN A + ++++ P + V + + G L+C V G P
Sbjct: 722 HNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAG---VLNCSVDGYPPP 778
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLE-----FKDVTKADAGDYVCKASNVAGSDTSK 1388
++ W A P +L + V + D G Y+C+ASN G+D SK
Sbjct: 779 KVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISK 838
Query: 1389 SKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG 1568
S V S P + ++ G+ ++W KG
Sbjct: 839 S--------------MFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKG 884
Query: 1569 KW-----RQLNQGGRIFIHQKGDE--AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
R + I GDE + L+++ + DS + C A N +GE + L
Sbjct: 885 DTVIDPDRVMRYA--IATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLT 942
Query: 1728 VNERKKQEKIE 1760
V E ++E
Sbjct: 943 VQEPPDPPELE 953
Score = 94.4 bits (233), Expect = 3e-19
Identities = 127/570 (22%), Positives = 212/570 (37%), Gaps = 24/570 (4%)
Frame = +3
Query: 42 CQLAGTPEIGVSWY--KGDTKLRPTATYKMHFRNNVATLVFNQVDSND---SGEYICRAE 206
C AG+P + WY GD +H + F+ N +Y C AE
Sbjct: 106 CPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTAE 165
Query: 207 NSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGS--EPIS-VSWFKD 377
N+ G++ S + P ++ ++ D + G VF+C + S E +S VSW KD
Sbjct: 166 NAAGKIRSPNIRVKAVFREP--YTVRVEDQRSMRGSVAVFKCLIPSSVQEYVSVVSWEKD 223
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGS---ASSSARLILTE-G 545
+ + + ++ + D Y C + S+ ARL +T+
Sbjct: 224 TVAIVPENRFLITSHGGLYISDVQKEDA--LSTYRCITKHKYSGETRQSNGARLSVTDPA 281
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
+ P + G + + C +G + W KD R + + + +
Sbjct: 282 ESIPTILDGFHSQEVWAGHTMELPCTASGYPIPAIRWLKDGRPLPADSR----WTKRITG 337
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
LTI + D+G Y C N G T L + I P + ++ G++ L
Sbjct: 338 LTISDLRTEDSGTYICEVTNTFGSAEVTGTLTV----IDPLHVTLTPKNLKTGIGSTVIL 393
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+ GS ++ WY+N + P+ I +N LL + A +G Y C +
Sbjct: 394 SCALLGSPEFTIRWYRNTELVLPSEAISIRGLSNETLL-ITSAQKSHSGAYQCFATRKTQ 452
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI--K 1259
+A + IV+++ P + V+ GE L C +G+ P I W I
Sbjct: 453 TAQDFAIIVLED--GTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTITWALDDEPIVRD 510
Query: 1260 PSDRCS-FSFANGTAV--LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
S R + ++ ++GT + + D G Y C A N GS ++++
Sbjct: 511 GSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNSVGSAEYQARIN---------- 560
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTA-----TFI-AKVGGDPIPNVKWTKGKWRQLNQG 1592
V P SIR + TA T + +V G P ++KW K L
Sbjct: 561 ------------VRGPPSIRAMRNITAVAGRDTLVNCRVIGYPYYSIKWYKDA-LLLPDN 607
Query: 1593 GRIFIHQKGDEAKLEIRDTTK-TDSGLYRC 1679
R + + G L++ D K D G Y C
Sbjct: 608 HRQVVFENG---TLKLTDVQKGMDEGEYLC 634
Score = 84.3 bits (207), Expect = 4e-16
Identities = 102/436 (23%), Positives = 172/436 (39%), Gaps = 21/436 (4%)
Frame = +3
Query: 15 TVGDSASLQCQLA-GTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
++G + C ++ G I ++W K + + + + +++L + V +G Y
Sbjct: 667 SIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNY 726
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A N+ VS L V ++PP F Q + G V C+V G P V W
Sbjct: 727 TCIASNAAATVSRERQLIV---RVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWK 783
Query: 372 K---DGRPLKDGPNIQTSFLDNV--ATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
G P + P T + + ++L I G Y C A+N +G+ S + +
Sbjct: 784 HAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLT 843
Query: 537 TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGG--NYQISYL 710
+ P A+ G + + C G +PI + W K + I Y I+
Sbjct: 844 V--KIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATK 901
Query: 711 ENS----AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE 878
+N + L + D+GD+ ++C+A+N G+D QL ++E PP +
Sbjct: 902 DNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPEL------EIR 955
Query: 879 ETEGNSFRLE--GRVAGSQPIS--VAWYKNNVEI----HPTANCEITFKNNALLLQVKKA 1034
E + S L R G+ I+ YKN + T N T N A ++ + A
Sbjct: 956 EVKARSMNLRWTQRFDGNSIITGFDIEYKNKTDSWDFKQSTRNISPTI-NQANIVDLHPA 1014
Query: 1035 SMGDAGLYTC-KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRG 1211
S+ +Y+ K+ S T S P PP+ D L PVT
Sbjct: 1015 SVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPM-DVTLQPVT--------------- 1058
Query: 1212 SEPIRIQWLKAGREIK 1259
S+ I++ W +E++
Sbjct: 1059 SQSIQVTWKAPKKELQ 1074
Score = 67.0 bits (162), Expect = 6e-11
Identities = 109/500 (21%), Positives = 185/500 (37%), Gaps = 18/500 (3%)
Frame = +3
Query: 285 LRDVQETVGLPVVFECAVSGSEPISVSWF-KDGRPLKDGPNIQTSFLDNVATLNIFQTD- 458
L+ V + + VV C +GS ++ W+ G + D P+I+ + L F
Sbjct: 91 LQQVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSA 150
Query: 459 -RSFA--GQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVT 629
SF Y CTA N G S + R P + + + ++ G A F+C +
Sbjct: 151 FNSFIHDNDYFCTAENAAGKIRSPNIRVKAVFREP--YTVRVEDQRSMRGSVAVFKCLIP 208
Query: 630 GTQP---IKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDT-GQYTCYAVNEVG- 794
+ V+W KD I + I+ + L I V K D Y C ++
Sbjct: 209 SSVQEYVSVVSWEKDTVAIVPENRFLIT---SHGGLYISDVQKEDALSTYRCITKHKYSG 265
Query: 795 --KDSCTAQLNIKE--RLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNV 962
+ S A+L++ + IP S+ V G++ L +G ++ W K+
Sbjct: 266 ETRQSNGARLSVTDPAESIPTILDGFHSQEV--WAGHTMELPCTASGYPIPAIRWLKDGR 323
Query: 963 EIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVF 1142
+ A+ T + L + + D+G Y C+V+N GSA T ++ + +P +
Sbjct: 324 PL--PADSRWTKRITGLTISDLRTE--DSGTYICEVTNTFGSAEVTGTLTVIDPLHVTLT 379
Query: 1143 DQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDV 1322
++L G + LSC + GS I+W + + PS+ S + +L
Sbjct: 380 PKNL---KTGIGSTVILSCALLGSPEFTIRWYRNTELVLPSEAISIRGLSNETLL-ITSA 435
Query: 1323 TKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEK 1502
K+ +G Y C A+ + + + DG VS V
Sbjct: 436 QKSHSGAYQCFATRKTQTAQDFAIIVLE--------------DGTPRIVSSFSEKVVNPG 481
Query: 1503 TTATFIAKVGGDPIPNVKWTKGKWRQLNQGG-RIFIHQKGDEAKLEIRDTTK---TDSGL 1670
+ + G P P + W + G R + D + + T D G+
Sbjct: 482 EQFSLMCAAKGAPPPTITWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGV 541
Query: 1671 YRCVAFNKHGEIESNVNLQV 1730
YRC A N G E + V
Sbjct: 542 YRCTARNSVGSAEYQARINV 561
Database: RefSeq49_BP.fasta
Posted date: Oct 17, 2011 1:42 PM
Number of letters in database: 17,681,374
Number of sequences in database: 33,088
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 33088
Number of Hits to DB: 72,103,580
Number of extensions: 1834465
Number of successful extensions: 12149
Number of sequences better than 1.0e-05: 180
Number of HSP's gapped: 7722
Number of HSP's successfully gapped: 887
Length of query: 667
Length of database: 17,681,374
Length adjustment: 109
Effective length of query: 558
Effective length of database: 14,074,782
Effective search space: 7853728356
Effective search space used: 7853728356
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)
+S G Y+CTA+N +G SS +++ E P F L ++ ESA F+C V
Sbjct: 297 LFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPTVP--FKKRLQDLEVREKESATFQCEV 354
Query: 627 TGTQP-IKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDS 803
QP + AW K+ + + Y I LT+ V D Y C ++
Sbjct: 355 --AQPATEAAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYIC--------ET 404
Query: 804 CTAQLNIKERLIPPSFTKKLSETVEETEGNS--FRLEGRVAGSQPISVAWYKNNVEIHPT 977
+ E + + T+KL G++ F +E V V W +N E+
Sbjct: 405 TEGSRTVAELSVQGNLTRKLPRKTAVRTGDTAIFWVELAVPEG---PVRWLRNQEEMVAG 461
Query: 978 ANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT 1157
IT + L + + ++ D G +V+ +G T+ + P++PP++
Sbjct: 462 GRVAITAEGTCHTLTIFQCTLEDMG----EVAFVSGGCRTTTQFCVSAPRRPPLYPP-AD 516
Query: 1158 PVTVSEGE---FLQLSCHVRGSEPIRIQ-WLKAGREIKPSDRCSFSFANGTAVLEFKDVT 1325
PV ++ E L S G P+ I ++ R++ A A EF
Sbjct: 517 PVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHEAGWLATTEFTITG 576
Query: 1326 KADAGDYVCKASNV 1367
A+ GD+ + S +
Sbjct: 577 VAEEGDFQFRVSAI 590
Score = 103 bits (257), Expect = 5e-22
Identities = 121/503 (24%), Positives = 187/503 (37%), Gaps = 36/503 (7%)
Frame = +3
Query: 267 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNI 446
P F + + +VG C + G+ VSW KD +P++ G + + +V L I
Sbjct: 9 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTI 68
Query: 447 FQTDRSFAGQYSCTATNPIGSASSSARL-ILTEG---RNPPFFDIPLAPVDAVVGESADF 614
+GQY C A N IG A ++ L + +EG P F + + G A F
Sbjct: 69 LDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATF 128
Query: 615 ECHVTGTQPIKVAWAKDNREI--RSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNE 788
C V G+ V+W+KD R + + ++ S+ L I D G Y A N
Sbjct: 129 RCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENP 188
Query: 789 VGKDSCTAQL---------------------NIKERL-------IPPSFTKKLSETVEET 884
+G S A L ++++R IPPS + T T
Sbjct: 189 LGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVT 248
Query: 885 EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNA--LLLQVKKASMGDAGLY 1058
EG RL V G W K+ ++ + +++ +L++ D GLY
Sbjct: 249 EGKHARLSCFVTGEPKPETVWKKDG-QLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLY 307
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWL 1238
TC SN G + +V++EP P F + L + V E E C V W
Sbjct: 308 TCTASNLVGQTYSSVLVVVREPTVP--FKKRLQDLEVREKESATFQCEV-AQPATEAAWF 364
Query: 1239 KAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXX 1418
K + S + L ++V+ D Y+C+ + GS T
Sbjct: 365 KEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYICETTE--GSRT------------ 410
Query: 1419 XXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR 1598
V G L P+ V TA F ++ P V+W + + ++ GGR
Sbjct: 411 ----VAELSVQGNL-TRKLPRKTAVRTGDTAIFWVELAVPEGP-VRWLRNQ-EEMVAGGR 463
Query: 1599 IFIHQKGDEAKLEIRDTTKTDSG 1667
+ I +G L I T D G
Sbjct: 464 VAITAEGTCHTLTIFQCTLEDMG 486
Score = 102 bits (253), Expect = 1e-21
Identities = 114/453 (25%), Positives = 188/453 (41%), Gaps = 22/453 (4%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G +A L+C+L+ + V W KG +L P A Y+M A L+ + V+ D+GEY
Sbjct: 4867 VDEGATARLRCELS-REAVSVEWRKGSLQLFPCAKYQMVQEGTTAELLVHGVEQEDAGEY 4925
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEP-ISVSW 368
C A G S L+V+ K P F L+ ++ G C +S +EP V W
Sbjct: 4926 TCDA----GHTQSIARLSVRAPK--PKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQW 4979
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K+G L G + V L I + G+Y+C +G + A L + E
Sbjct: 4980 LKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTGEYACL----VGGQKTLASLRVKE-- 5033
Query: 549 NPPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL-ENS 719
P I VD V E +F C V+ V W ++S +++ L +
Sbjct: 5034 --PEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLADGC 5091
Query: 720 AHLTILK-VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
H+ LK V D G + + VG S +AQL ++ +P + + V+ +EG
Sbjct: 5092 THVLQLKGVTLEDAGTVSFH----VGGLSSSAQLTVR---VPEVTVLEPLKDVQLSEGQD 5144
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNAL-LLQVKKASMGDAGLYTCKVS 1073
R++ + W V + +IT + L LL + K ++ DAG T +V
Sbjct: 5145 AHFRCRLSRASGQEARWALGGVPLQCNEMNDITVEQGTLYLLTLHKVTLEDAGTITLQVG 5204
Query: 1074 NDAGSA--LCTSSIVIKEPKK-------PPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIR 1226
+ + A T++ V++ + +F+ L+ V+ +L V SE +
Sbjct: 5205 SCSSEAQLKVTANTVLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVE 5264
Query: 1227 IQWLKAG-------REIKPSDRCSFSFANGTAV 1304
+ + + G + +KP D C +F G V
Sbjct: 5265 VVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVV 5297
Score = 94.0 bits (232), Expect = 4e-19
Identities = 134/585 (22%), Positives = 226/585 (38%), Gaps = 17/585 (2%)
Frame = +3
Query: 96 KLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR--AENSVGEVSSSTFLTVQEQKLPP 269
KL A + H +AT F + G++ R A N G+ F
Sbjct: 552 KLGAYAWSRCHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPML 611
Query: 270 SFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVA-TLNI 446
+ L+ V+ G V F ++ + S WF DG LK +I D L I
Sbjct: 612 AVKTPLKAVEAVEGGEVTFSVDLTVAS--SGEWFLDGEALK-ASSIYVIRCDRTRHMLTI 668
Query: 447 FQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVG---ESADFE 617
+ G N I +S ++++ P +P A V+ E A
Sbjct: 669 REVPARLHGAQLKFVANGI---ETSIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLL 725
Query: 618 CHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGK 797
++ Q V W KD RE+ G Y++ L + V + D G Y C V +
Sbjct: 726 AELSD-QAAAVTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYEC-----VSR 779
Query: 798 DSCTA-QLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHP 974
S TA QL ++E + + ++ V+ GNS L V +Q V W+K+ ++
Sbjct: 780 GSRTAYQLLVQEPKLVFAKGQQAHSEVKAEAGNSATLSCEVTQAQ-TEVTWFKDGKKLSS 838
Query: 975 TANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVF---D 1145
++ + + L V++A DAG Y+C +AG + + + EPK VF
Sbjct: 839 SSKVRMEASGCSRRLVVQQAGKADAGEYSC----EAGGQKLSFRLDVAEPKL--VFAKGQ 892
Query: 1146 QHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVT 1325
Q + V G LSC V ++ + W K G+++ S + + + L +
Sbjct: 893 QAHSEVKAEAGASATLSCEVAQAQ-TEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAG 951
Query: 1326 KADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS---IRVV 1496
KADAG+Y C+A S + K+ F E Q+ ++
Sbjct: 952 KADAGEYSCEAGGQKLS------------------FRLDVAEPKMVFAKEQQARSEVKAE 993
Query: 1497 EKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYR 1676
+AT +V V W K ++L+ ++ + G +L ++ K D+G Y
Sbjct: 994 AGASATLSCEV-AQAQTEVTWFK-DGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYS 1051
Query: 1677 CVAFNKHGEIESNVNLQVNERK----KQEKIEGDLRAMLKKTPVL 1799
C A G + + L V E K K+++ +++A + + L
Sbjct: 1052 CEA----GGQKLSFRLDVTEPKLVFAKEQQARSEVKAEVGNSATL 1092
Score = 94.0 bits (232), Expect = 4e-19
Identities = 137/586 (23%), Positives = 224/586 (38%), Gaps = 7/586 (1%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ V ++ L +A V+W K ++R + ++ + TL DS
Sbjct: 2093 PLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDS 2152
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
Y CR VG+ VQ +++ FS+ L V+ +G V+ C +S E V
Sbjct: 2153 AIYSCR----VGKEGQD--FPVQVEEVAAKFSKPLEPVEGELGGTVMLVCELS-PEQAEV 2205
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W L+ G Q + TL + A +Y C + + +SARL +
Sbjct: 2206 VWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDD----RTSARLTVKV 2261
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
R F L+ + A G+ A F+C V V W KD +++ + + S
Sbjct: 2262 PRVVKFTS-GLSAMVAEEGQEATFQC-VVSPSDAGVTWYKDGMQLQPSEKFVMVESGASR 2319
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLS-ETVEETEGNSF 899
LTIL + D GQ T E S +A L ++E P F KKL +TVEE S
Sbjct: 2320 SLTILGLTLEDAGQVTV----EAEGASSSAALRVRE--APVLFKKKLEPQTVEER--TSV 2371
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
LE + P V W +N + P+ N EI + L ++ D G + C+ +D
Sbjct: 2372 TLEVELTRPWP-EVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADRGFFGCETPDD 2430
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
A ++ +++ + + L V E + + +E + W + G ++
Sbjct: 2431 KTQA--KLNVEMRQVR----LVRGLQEVEAKEQGTASMDVELSHAE-VEGSWTRDGLRLQ 2483
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
P +C + +L + D+G +A V S
Sbjct: 2484 PGPKCHLAVQGPVHILTLSALQPQDSGLVAFRAEGVHTS--------------------- 2522
Query: 1440 XXVDGKLFFVSEPQSI-RVVEKTTATFIAKVG-----GDPIPNVKWTKGKWRQLNQGGRI 1601
+L P S RV++ AT KV P+ +V+W K +L G I
Sbjct: 2523 ----ARLIVTELPVSFTRVLQDVVATQKEKVTLECELSRPV-DVRWLK-DGVELRAGKAI 2576
Query: 1602 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
I +G L I D G+Y C A + +++ +L+V R
Sbjct: 2577 GIVAQGTCRSLVIYRCETGDQGVYVCDAL----DAQTSASLRVQGR 2618
Score = 94.0 bits (232), Expect = 4e-19
Identities = 121/548 (22%), Positives = 196/548 (35%), Gaps = 96/548 (17%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKM-HFRNNVATLVFNQVDSNDSGEYI 194
VGD L+C LA ++ W K +L Y + ++ +L+ + DSG Y
Sbjct: 5786 VGDVLRLECVLATKTDMRACWLKDGIELTDGRHYHIDQLKDGTCSLLVTGLAPTDSGRYT 5845
Query: 195 CRAENSVGEVSSSTFLTVQEQK----------LPPSFSRQLRDVQET--------VGLPV 320
C+ G VS S + V + L +F R R + +
Sbjct: 5846 CQVSTKSGRVSHSACVVVSGTESEAESSSGGELDDAFRRAARRLHRLFRTKSPAELSEEE 5905
Query: 321 VFECAVSG----SEPISVSWFKDGR--------PLKDGPNIQTSFLDNVATLNIFQTDRS 464
+F A G EP +++ L + T F + AT+ I + S
Sbjct: 5906 LFLSADEGPGEPEEPADWQTYREDENFVCIRFESLAEARQAVTCFRNMFATMGI-GVEIS 5964
Query: 465 FAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPV--------DAVVGESADFEC 620
Q IG + + + + P APV D G F+C
Sbjct: 5965 LGEQGPRGVEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDC 6024
Query: 621 HVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH-LTILKVDKGDTGQYTCYAVNEVGK 797
VTG V W KD + + +Y I+ + H L I V D G Y C A N +G
Sbjct: 6025 VVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGV 6084
Query: 798 DSCTAQLNI----------------------------KERLIPPSFTKKLSETVEETEGN 893
S A+L + +E+ S +L + +EE +
Sbjct: 6085 SSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGTESDEGQLPQVLEELKDL 6144
Query: 894 SF-------RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAG 1052
+ + +V G + W+K+ + + + +T K L++ + D+G
Sbjct: 6145 QVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTREDSG 6204
Query: 1053 LYTCKVSNDAGSALCTSSIVIK---EPKKPPVFDQH-----------LTPVTVSEGEFLQ 1190
Y +SN G+A ++ ++++ EP++ P D H TP V G +
Sbjct: 6205 QYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSIT 6264
Query: 1191 LSCHVRGSEPIRIQWLKAGRE-----IKPSDRCSFSFANGTA--VLEFKDVTKADAGDYV 1349
S V G + WLK E I P D ++ A+ + L DV + G Y
Sbjct: 6265 FSVKVEGHPAPSVHWLKEEAEKGVLWIGP-DTPGYTMASSSKQHSLVLLDVGRQHQGTYT 6323
Query: 1350 CKASNVAG 1373
C A+N AG
Sbjct: 6324 CIATNPAG 6331
Score = 90.9 bits (224), Expect = 3e-18
Identities = 83/325 (25%), Positives = 122/325 (37%), Gaps = 57/325 (17%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHF-RNNVATLVFNQVDSNDSGEYIC 197
G S C + G P V W+K L Y ++ + L+ V D G Y C
Sbjct: 6017 GYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRC 6076
Query: 198 RAENSVGEVSSSTFLTVQ-----------------------------------EQKLPPS 272
AENS+G S+ L V+ ++ P
Sbjct: 6077 LAENSMGVSSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGTESDEGQLPQ 6136
Query: 273 FSRQLRDVQETVGLPVV-FECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIF 449
+L+D+Q G + F+ V G + WFKDG+PL +I+ + + TL I
Sbjct: 6137 VLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIV 6196
Query: 450 QTDRSFAGQYSCTATNPIGSASSSARLIL---TEGRNPPFFDI-----------PLAPVD 587
R +GQY+ +N +G+A SSARL++ +E P D+ P
Sbjct: 6197 SVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKK 6256
Query: 588 AVVGESADFECHVTGTQPIKVAWAKDNREI------RSGGNYQISYLENSAHLTILKVDK 749
G S F V G V W K+ E Y ++ L +L V +
Sbjct: 6257 VKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGR 6316
Query: 750 GDTGQYTCYAVNEVGKDSCTAQLNI 824
G YTC A N G+ C+A L+I
Sbjct: 6317 QHQGTYTCIATNPAGQALCSASLHI 6341
Score = 88.2 bits (217), Expect = 2e-17
Identities = 98/399 (24%), Positives = 156/399 (39%), Gaps = 70/399 (17%)
Frame = +3
Query: 129 FRNNVATLVFN-QVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLP--------PSFSR 281
FRN AT+ ++ + G E +G+V+ + V K P P F
Sbjct: 5950 FRNMFATMGIGVEISLGEQGPR--GVEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLT 6007
Query: 282 QLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVA-TLNIFQTD 458
+L++ G P+ F+C V+G SV WFKDG+ L++ + + L I
Sbjct: 6008 ELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVV 6067
Query: 459 RSFAGQYSCTATNPIGSASSSARLILT--------------------------------- 539
+ G Y C A N +G +S+ A L +
Sbjct: 6068 PADMGVYRCLAENSMGVSSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGT 6127
Query: 540 ---EGRNPPFF----DIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQ 698
EG+ P D+ +AP + A F+ V G K+ W KD + + + + +
Sbjct: 6128 ESDEGQLPQVLEELKDLQVAPGTRL----AKFQLKVKGYPAPKLYWFKDGQPLTTSDHIR 6183
Query: 699 ISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQL--------------NIKERL 836
++ + L I+ V + D+GQY Y N VG +A+L ++ ERL
Sbjct: 6184 MTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERL 6243
Query: 837 IPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVE-----IHP-TANCEITF 998
+PP +K + + G+S +V G SV W K E I P T +
Sbjct: 6244 VPPRILEKFTPK-KVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMAS 6302
Query: 999 KNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVI 1115
+ L + G YTC +N AG ALC++S+ I
Sbjct: 6303 SSKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHI 6341
Score = 84.7 bits (208), Expect = 2e-16
Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 3/180 (1%)
Frame = +3
Query: 264 PPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGP-NIQTSFLDNVATL 440
PP F +L D +G V C V+G+ VSW+KDG+P++ P +I D TL
Sbjct: 6888 PPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTL 6947
Query: 441 NIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFEC 620
+ +GQY C A + G+AS+ ++++ + PP F + V GE A C
Sbjct: 6948 ILDNLTGIDSGQYMCFAASAAGNASTLGKILV---QVPPRFVNKVRATPFVEGEDAQITC 7004
Query: 621 HVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL--KVDKGDTGQYTCYAVNEVG 794
V G ++ W KD + G Y++ S L ++ K D G Y C VN +G
Sbjct: 7005 TVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLG 7064
Score = 77.8 bits (190), Expect = 3e-14
Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 3/194 (1%)
Frame = +3
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNY-QISYLENSAHL 728
PP F+ LA A +GE+ C VTGT V+W KD + + ++ I + S L
Sbjct: 6888 PPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTL 6947
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
+ + D+GQY C+A + G S ++ ++ +PP F K+ T EG ++
Sbjct: 6948 ILDNLTGIDSGQYMCFAASAAGNASTLGKILVQ---VPPRFVNKVRAT-PFVEGEDAQIT 7003
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITF--KNNALLLQVKKASMGDAGLYTCKVSNDA 1082
V G+ + WYK+ + P + ++ L+L ++ AS D G Y C++ N
Sbjct: 7004 CTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRL 7063
Query: 1083 GSALCTSSIVIKEP 1124
GS + ++ P
Sbjct: 7064 GSTRGGGELYMQSP 7077
Score = 72.8 bits (177), Expect = 9e-13
Identities = 49/179 (27%), Positives = 76/179 (42%), Gaps = 6/179 (3%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHF----RNNVATLVFNQVDSNDSG 185
+G++ L C++ GTP+ VSWYK +P H + TL+ + + DSG
Sbjct: 6902 LGETVKLACRVTGTPKPIVSWYKDG---KPVEVDPHHILIEDPDGSCTLILDNLTGIDSG 6958
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y+C A ++ G S+ + VQ +PP F ++R G C V G+ +
Sbjct: 6959 QYMCFAASAAGNASTLGKILVQ---VPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIR 7015
Query: 366 WFKDGRPLKDGPNIQ--TSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
W+KDG L G + V L I + G Y C N +GS L +
Sbjct: 7016 WYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYM 7074
Score = 72.4 bits (176), Expect = 1e-12
Identities = 57/199 (28%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = +3
Query: 795 KDSCTAQLNIKERLI-PPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNN--VE 965
K+ C Q + + + PP F ++L++ E G + +L RV G+ V+WYK+ VE
Sbjct: 6872 KEICGIQQRLAQPVWRPPEFEEELADCTAEL-GETVKLACRVTGTPKPIVSWYKDGKPVE 6930
Query: 966 IHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFD 1145
+ P + I + + L + + D+G Y C ++ AG+A I++ + PP F
Sbjct: 6931 VDPH-HILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILV---QVPPRFV 6986
Query: 1146 QHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSF--SFANGTAVLEFKD 1319
+ EGE Q++C V G+ +I+W K G + P +R +G VL +
Sbjct: 6987 NKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQA 7046
Query: 1320 VTKADAGDYVCKASNVAGS 1376
+K D G Y C+ N GS
Sbjct: 7047 ASKEDLGHYECELVNRLGS 7065
Score = 69.7 bits (169), Expect = 8e-12
Identities = 59/250 (23%), Positives = 104/250 (41%), Gaps = 16/250 (6%)
Frame = +3
Query: 1128 KPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK-PSDRCSFSFANGTAV 1304
+PP F++ L T GE ++L+C V G+ + W K G+ ++ +G+
Sbjct: 6887 RPPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCT 6946
Query: 1305 LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS 1484
L ++T D+G Y+C A++ AG+ ++ K+ V FV++ ++
Sbjct: 6947 LILDNLTGIDSGQYMCFAASAAGNASTLGKI---------------LVQVPPRFVNKVRA 6991
Query: 1485 IRVVEKTTATFIAKVGGDPIPNVKWTK--------GKWRQLNQGGRIFIHQKGDEAKLEI 1640
VE A V G P P ++W K ++R LN+ + L I
Sbjct: 6992 TPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNE-------PRSGVLVLVI 7044
Query: 1641 RDTTKTDSGLYRCVAFNKHGEIE-------SNVNLQVNERKKQEKIEGDLRAMLKKTPVL 1799
+ +K D G Y C N+ G + L+ ++ +E+I + ++T V
Sbjct: 7045 QAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEVTEQETKVP 7104
Query: 1800 KKGAGEEEEI 1829
KK EE I
Sbjct: 7105 KKTVIIEETI 7114
Score = 68.9 bits (167), Expect = 1e-11
Identities = 92/404 (22%), Positives = 149/404 (36%), Gaps = 31/404 (7%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P V S +L+ +L P V W + L P+ ++ LV V D
Sbjct: 2362 PQTVEERTSVTLEVELT-RPWPEVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADR 2420
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G + C + + L V+ +++ R L++V+ + +S +E +
Sbjct: 2421 GFFGCETPDDKTQAK----LNVEMRQV--RLVRGLQEVEAKEQGTASMDVELSHAE-VEG 2473
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SW +DG L+ GP + V L + +G + A +SARLI+TE
Sbjct: 2474 SWTRDGLRLQPGPKCHLAVQGPVHILTLSALQPQDSGLVAFRAEG----VHTSARLIVTE 2529
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L V A E EC ++ +P+ V W KD E+R+G I
Sbjct: 2530 --LPVSFTRVLQDVVATQKEKVTLECELS--RPVDVRWLKDGVELRAGKAIGIVAQGTCR 2585
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I + + GD G Y C A++ +A L ++ R F + L+E E + +
Sbjct: 2586 SLVIYRCETGDQGVYVCDALDA----QTSASLRVQGRTYTLIFRRVLAEDAGEVKFVAEN 2641
Query: 903 LEGR---------VAGSQPI----------------------SVAWYKNNVEIHPTANCE 989
E R V +P+ V W+K VE+ E
Sbjct: 2642 AESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGGVELQSGPKYE 2701
Query: 990 ITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKE 1121
+ L + D YTC DAG+ ++ ++E
Sbjct: 2702 VVSDGLYRKLVINDVQPEDEDTYTC----DAGNVKTSAQFFVEE 2741
Score = 68.2 bits (165), Expect = 2e-11
Identities = 51/190 (26%), Positives = 76/190 (40%), Gaps = 1/190 (0%)
Frame = +3
Query: 1167 VSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDY 1346
VS G+ LSC + G+ + W K + ++ R + L D+ D+G Y
Sbjct: 20 VSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGDSGQY 79
Query: 1347 VCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAK 1526
VC+A N G + + + F+ P SIRV E ATF +
Sbjct: 80 VCRARNAIGEAFAAVGLRVDSEGTC--------AEQAPHFLLRPTSIRVREGADATFRCR 131
Query: 1527 VGGDPIPNVKWTK-GKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
VGG P P V W+K G+ + + + G+ + L IR D G Y A N G
Sbjct: 132 VGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGS 191
Query: 1704 IESNVNLQVN 1733
+ L V+
Sbjct: 192 ASAAAALVVD 201
Score = 58.9 bits (141), Expect = 1e-08
Identities = 87/403 (21%), Positives = 144/403 (35%), Gaps = 16/403 (3%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKM-HFRNNVA-TLVFNQVDSNDSGEYI 194
G A +CQL+ +W D + + ++ +F N + L+ + DS
Sbjct: 5231 GGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDS---- 5286
Query: 195 CRAENSVGEVSSSTFLTVQEQKL----PPSFSRQLRDVQETVGLPVVFECAVSGSEPIS- 359
CR G+V +S FLTV+ +L PP D G+ V F C +S + P+
Sbjct: 5287 CRVTFLAGDVVTSAFLTVRGWRLEVLEPP------HDASVKAGMQVRFTCILSEAVPVGE 5340
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVA-TLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
+W+ +G ++ T D L + AG+ + A + + SA S
Sbjct: 5341 ATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQHAGEVTFAARDAVASARLSV---- 5396
Query: 537 TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIK-----VAWAKDNREIRSGGNYQI 701
+P P DA V +D ++ P+ + + + S G +Q+
Sbjct: 5397 --------LALPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQL 5448
Query: 702 SY-LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE 878
+ L + + G T ++ AV G + P ET +
Sbjct: 5449 CHDLVPGPECVVDDLVPGKTYRFRVAAVGPAGAGEPVHLPQMAPAPAPAPAPAPAPETRQ 5508
Query: 879 ETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
G LE VA V W+K I P + E+ + +L +K D G Y
Sbjct: 5509 AVVGEDICLELEVAADGG-EVVWHKGTERIQPGGHFEVLSRGQRQMLVIKGFRTEDQGEY 5567
Query: 1059 TC-KVSNDAGSALCTSSIVIKEPKKPPVFDQ-HLTPVTVSEGE 1181
C + S T ++V+ V Q L P EG+
Sbjct: 5568 RCGPIQGLPSSGAATFNVVMTSGSGDEVPAQPSLPPEAAQEGD 5610
Score = 56.2 bits (134), Expect = 9e-08
Identities = 52/232 (22%), Positives = 94/232 (40%), Gaps = 11/232 (4%)
Frame = +3
Query: 1119 EPKKPPVFDQHLTPVTVSEGEFL-QLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANG 1295
E + P V ++ L + V+ G L + V+G ++ W K G+ + SD +
Sbjct: 6131 EGQLPQVLEE-LKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKT 6189
Query: 1296 TAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV----TXXXXXXXXXXXXXXXVDGKLF 1463
LE VT+ D+G Y SN G+ S +++ V ++
Sbjct: 6190 LHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRIL 6249
Query: 1464 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGK------WRQLNQGGRIFIHQKGDE 1625
P+ ++ ++ TF KV G P P+V W K + W + G + +
Sbjct: 6250 EKFTPKKVK--RGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPG-YTMASSSKQ 6306
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAML 1781
L + D + G Y C+A N G+ + +L ++ K+E+ E A++
Sbjct: 6307 HSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALI 6358
Score = 51.6 bits (122), Expect = 2e-06
Identities = 31/90 (34%), Positives = 47/90 (52%)
Frame = +3
Query: 1464 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIR 1643
F++ P++ V AT ++ G+P P+V W K + + + G R + Q GD +L I
Sbjct: 11 FLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDR-QPVEAGARFRLAQDGDVYRLTIL 69
Query: 1644 DTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
D DSG Y C A N GE + V L+V+
Sbjct: 70 DLALGDSGQYVCRARNAIGEAFAAVGLRVD 99
>ref|NP_001164983.1| obscurin isoform 1 [Mus musculus].
Length = 8025
Score = 160 bits (405), Expect = 3e-39
Identities = 153/600 (25%), Positives = 256/600 (42%), Gaps = 10/600 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK G SA+L C++A + V+W+K KL ++ +M LV Q D+G
Sbjct: 873 VKAEAGASATLSCEVAQA-QTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAG 931
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR-DVQETVGLPVVFECAVSGSEPISV 362
EY C A G S L V E K+ + +Q R +V+ G C V+ ++ V
Sbjct: 932 EYSCEA----GGQKLSFRLDVAEPKMVFAKEQQARSEVKAEAGASATLSCEVAQAQ-TEV 986
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+WFKDG+ L ++ L + Q ++ AG+YSC A G S RL +TE
Sbjct: 987 TWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEA----GGQKLSFRLDVTE 1042
Query: 543 GRNPPFFDIPL-APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
+ + + V A VG SA C V Q +V W KD +++ S ++ S
Sbjct: 1043 PKLVFAKEQQARSEVKAEVGNSATLSCEVAQAQ-TEVTWFKDGKKLSSSSKVRMEASGCS 1101
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L + + K D G+Y+C E G + +L++ E + + ++ V+ GNS
Sbjct: 1102 RRLVVQQAGKADAGEYSC----EAGGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGNSA 1157
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L VA +Q V W+K+ ++ ++ + + L V++A DAG Y+C +
Sbjct: 1158 TLSCEVAQAQ-TEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSC----E 1212
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
AG + + + EPK +Q + V G LSC V ++ + W K G+++
Sbjct: 1213 AGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQ-TEVTWFKDGKKL 1271
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
S + + + L + KADAG+Y C+A S
Sbjct: 1272 SSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAEGQKLS------------------FR 1313
Query: 1437 XXXVDGKLFFVSEPQS---IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
+ KL F E Q+ ++ +AT +V V W K ++L+ ++ +
Sbjct: 1314 LDVAEPKLVFAKEQQARSEVKAEAGASATLSCEV-AQAQTEVTWFK-DGKKLSSSSKVRV 1371
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK----KQEKIEGDLRA 1775
G +L ++ K D+G Y C A G + + L V E K K+++ +++A
Sbjct: 1372 EASGCSRRLVVQQAGKADAGEYSCEA----GGQKLSFRLDVAEPKLVFAKEQQANSEVKA 1427
Score = 156 bits (395), Expect = 5e-38
Identities = 144/566 (25%), Positives = 238/566 (42%), Gaps = 6/566 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK G SA+L C++A + V+W+K KL ++ +M LV Q D+G
Sbjct: 1241 VKAEAGASATLSCEVAQA-QTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAG 1299
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR-DVQETVGLPVVFECAVSGSEPISV 362
EY C AE S L V E KL + +Q R +V+ G C V+ ++ V
Sbjct: 1300 EYSCEAEGQ----KLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEVAQAQ-TEV 1354
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+WFKDG+ L ++ L + Q ++ AG+YSC A G S RL + E
Sbjct: 1355 TWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEA----GGQKLSFRLDVAE 1410
Query: 543 GRNPPFFDIPL-APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
+ + + V A G SA C V Q +V W KD +++ S ++ S
Sbjct: 1411 PKLVFAKEQQANSEVKAEAGASATLSCEVAQAQ-TEVTWFKDGKKLSSSSKVRVEASGCS 1469
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L + + K D G+Y+C E G + +L++ E + + ++ V+ G S
Sbjct: 1470 RRLVVQQAGKADAGEYSC----EAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASA 1525
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L VA +Q V W+K+ ++ ++ + + L V++A DAG Y+C +
Sbjct: 1526 TLSCEVAQAQ-TEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSC----E 1580
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
AG + + + EPK +Q + V G LSC V ++ + W K G+++
Sbjct: 1581 AGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQ-TEVTWFKDGKKL 1639
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXX 1436
S + + + L + KADAG+Y C+A S
Sbjct: 1640 SSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLS------------------FR 1681
Query: 1437 XXXVDGKLFFVSEPQS---IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
+ KL F E Q+ ++ +AT +V V W K ++L+ ++ +
Sbjct: 1682 LDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEV-AQAQTEVTWFK-DGKKLSSSSKVRV 1739
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVA 1685
G +L ++ K D+G Y C A
Sbjct: 1740 EASGCSRRLVVQQAGKADAGEYSCEA 1765
Score = 155 bits (391), Expect = 1e-37
Identities = 145/559 (25%), Positives = 222/559 (39%), Gaps = 2/559 (0%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+ T G A+L+CQ++ V W KG LR Y + + L + DSGE
Sbjct: 3776 EATEGTMATLRCQMSKAAP--VEWRKGSETLRDGDRYSLRQDGAMCELQIRGLTIEDSGE 3833
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y C G+ +S L+V+ LPP F LR + T G C +S + P V W
Sbjct: 3834 YTCVC----GQEKTSATLSVKA--LPPRFIEDLRSQEATEGTMATLRCQMSKAAP--VEW 3885
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K L DG V L I G+YSC SA+ + + +
Sbjct: 3886 RKGSETLGDGGRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKAL----- 3940
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP F L +A G A C ++ P++ W K + +R GG Y + L
Sbjct: 3941 -PPRFIEDLRSQEATEGTMATLRCQMSKAAPVE--WRKGSETLRDGGRYSLRQDGAVCEL 3997
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
I +D D GQY+C G++ +A L + +PP FT+ L + E TEG L
Sbjct: 3998 QIHDLDVEDAGQYSCVC----GQEKTSAVLTVD--ALPPKFTEGLKKE-EATEGTMVTL- 4049
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
R S+ +V W K + + LQ+ ++ DAG Y+C + S
Sbjct: 4050 -RCQMSKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTS 4108
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
A + + PP F + L +EG L C + + P ++W K + ++ D
Sbjct: 4109 ATLSVKAL------PPRFIEDLRSQEATEGTMATLRCQMSKAAP--VEWRKGSKTLRDGD 4160
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
R S L+ D+ D GDY C S T K
Sbjct: 4161 RYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKAP---------------- 4204
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPN--VKWTKGKWRQLNQGGRIFIHQKGD 1622
++ F Q+++ E + A+ ++ +PN + W+KG +L R Q+G
Sbjct: 4205 --QVVFQQPLQNLQAEEGSMASLRCELS---VPNAAMVWSKG-GLELQGDTRREARQQGC 4258
Query: 1623 EAKLEIRDTTKTDSGLYRC 1679
A+L +RD + D+G Y C
Sbjct: 4259 VAELLLRDLRREDAGEYSC 4277
Score = 153 bits (387), Expect = 4e-37
Identities = 154/589 (26%), Positives = 240/589 (40%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+ T G A+L+CQ++ V W KG L Y + V L + + D+GE
Sbjct: 3864 EATEGTMATLRCQMSKAAP--VEWRKGSETLGDGGRYSLRQNGAVCELQIHDLAVEDTGE 3921
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y C G+ +S L V+ LPP F LR + T G C +S + P V W
Sbjct: 3922 YSCVC----GQEKTSATLNVKA--LPPRFIEDLRSQEATEGTMATLRCQMSKAAP--VEW 3973
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K L+DG V L I D AGQYSC G +SA +LT
Sbjct: 3974 RKGSETLRDGGRYSLRQDGAVCELQIHDLDVEDAGQYSCVC----GQEKTSA--VLTVDA 4027
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP F L +A G C ++ + V W K + + GG Y + L
Sbjct: 4028 LPPKFTEGLKKEEATEGTMVTLRCQMS--KEATVEWRKGAKTLSDGGRYSLRQDGAMCEL 4085
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
I + D G+Y+C G++ +A L++K +PP F + L + E TEG L
Sbjct: 4086 QICGLAVEDAGEYSCVC----GQEKTSATLSVKA--LPPRFIEDL-RSQEATEGTMATLR 4138
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+++ + P+ W K + + + LQ+ ++ D G Y+C + S
Sbjct: 4139 CQMSKAAPVE--WRKGSKTLRDGDRYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTS 4196
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
A ++ +K P+ VF Q L + EG L C + + W K G E++
Sbjct: 4197 A----TLSVKAPQV--VFQQPLQNLQAEEGSMASLRCELSVPNAAMV-WSKGGLELQGDT 4249
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
R A L +D+ + DAG+Y C GS T+ + +
Sbjct: 4250 RREARQQGCVAELLLRDLRREDAGEYSC----TCGSQTTSATLMVTA------------- 4292
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
+ F+ E Q+ V E TA ++ + + +V+W KG QL + + Q+G A
Sbjct: 4293 -APVRFLRELQAQDVDEGATARLRCELSREAV-SVEWRKGSL-QLFPCAKYQMVQEGTTA 4349
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRA 1775
+L + + D+G Y C A G +S L V R + K + DL++
Sbjct: 4350 ELLVHGVEQEDAGEYTCDA----GHTQSIARLSV--RAPKPKFKTDLQS 4392
Score = 143 bits (360), Expect = 6e-34
Identities = 115/416 (27%), Positives = 174/416 (41%), Gaps = 40/416 (9%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V+VG A+L CQ+ G P VSW K + A +++ +V L + DSG+Y
Sbjct: 20 VSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGDSGQY 79
Query: 192 ICRAENSVGEVSSSTFLTVQEQ----KLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
+CRA N++GE ++ L V + + P F + ++ G F C V GS +
Sbjct: 80 VCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATFRCRVGGSPQPA 139
Query: 360 VSWFKDGRPL--KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
VSW KDGR L D P+++ + L I G Y A NP+GSAS++A L+
Sbjct: 140 VSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALV 199
Query: 534 L---TEGRNPPFFD-------------------IPLAPVDA-------VVGESADFECHV 626
+ E PP IP +P A G+ A C V
Sbjct: 200 VDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFV 259
Query: 627 TGTQPIKVAWAKDNREIRSGGNYQISYLENSAH-LTILKVDKGDTGQYTCYAVNEVGKDS 803
TG + W KD + + G + + E L IL + D G YTC A N VG+
Sbjct: 260 TGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNLVGQTY 319
Query: 804 CTAQLNIKERLIPPSFTKKLSE-TVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTA 980
+ + ++E +P F K+L + V E E +F+ E AW+K + +A
Sbjct: 320 SSVLVVVREPTVP--FKKRLQDLEVREKESATFQCE---VAQPATEAAWFKEETRLWASA 374
Query: 981 NCEITFKNNALLLQVKKASMGDAGLYTCKV---SNDAGSALCTSSIVIKEPKKPPV 1139
+I + L V+ S D +Y C+ S ++ K P+K V
Sbjct: 375 KYDIEEEGTERRLTVRNVSADDDAVYICETTEGSRTVAELSVQGNLTRKLPRKTAV 430
Score = 142 bits (358), Expect = 1e-33
Identities = 151/614 (24%), Positives = 235/614 (38%), Gaps = 13/614 (2%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+ T GD+ +LQC+L+ V W KG LR Y + V L + D+GE
Sbjct: 3528 EATEGDTTTLQCELSKAAP--VEWRKGTETLRDGDRYSLKQDGAVCELQIRSLTIADAGE 3585
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y+C + G+ +S LTV+ LP F L++ + T G C +S + P V+W
Sbjct: 3586 YLC----TCGQEKTSATLTVRA--LPAKFKDSLKNEEATEGTTATLSCELSKAAP--VTW 3637
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K + L+ G V L I + AG+YSC SA+ + R +
Sbjct: 3638 KKGPKTLQSGDKYVLRQDGAVCGLQIHGLTMADAGEYSCVCGQEKTSATLTVRGL----- 3692
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
P F L +A G +A C ++ P++ W K + ++ G Y + L
Sbjct: 3693 -PAKFIEDLRSQEATEGATAILRCELSKAAPVE--WRKGSETLKDGDRYTLRQDGAVCEL 3749
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
I + DTG Y+ +P FT+ L E TEG L
Sbjct: 3750 QIRGLAVVDTGTYS----------------------LPTKFTEGLRNE-EATEGTMATLR 3786
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+++ + P+ W K + + + LQ++ ++ D+G YTC + S
Sbjct: 3787 CQMSKAAPVE--WRKGSETLRDGDRYSLRQDGAMCELQIRGLTIEDSGEYTCVCGQEKTS 3844
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
A + + PP F + L +EG L C + + P+ +W K +
Sbjct: 3845 ATLSVKAL------PPRFIEDLRSQEATEGTMATLRCQMSKAAPV--EWRKGSETLGDGG 3896
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
R S L+ D+ D G+Y C S T K
Sbjct: 3897 RYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKALPPR------------- 3943
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F+ + +S E T AT ++ V+W KG L GGR + Q G
Sbjct: 3944 -----FIEDLRSQEATEGTMATLRCQMS--KAAPVEWRKGS-ETLRDGGRYSLRQDGAVC 3995
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE--------RKKQEKIEG---DLRA 1775
+L+I D D+G Y CV G+ +++ L V+ KK+E EG LR
Sbjct: 3996 ELQIHDLDVEDAGQYSCVC----GQEKTSAVLTVDALPPKFTEGLKKEEATEGTMVTLRC 4051
Query: 1776 MLKK--TPVLKKGA 1811
+ K T +KGA
Sbjct: 4052 QMSKEATVEWRKGA 4065
Score = 141 bits (356), Expect = 2e-33
Identities = 150/611 (24%), Positives = 233/611 (38%), Gaps = 7/611 (1%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+ T G + +L+C+L T E V W KG LR Y + V L + D+GE
Sbjct: 3440 EATEGTTVTLRCEL--TKEAPVEWKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGE 3497
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y C G+ +S LTV+ L F R+LR + T G +C +S + P V W
Sbjct: 3498 YSCVC----GQEKTSATLTVKA--LLVHFVRRLRSKEATEGDTTTLQCELSKAAP--VEW 3549
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K L+DG V L I + AG+Y CT SA+ + R +
Sbjct: 3550 RKGTETLRDGDRYSLKQDGAVCELQIRSLTIADAGEYLCTCGQEKTSATLTVRAL----- 3604
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
P F L +A G +A C ++ P V W K + ++SG Y + L
Sbjct: 3605 -PAKFKDSLKNEEATEGTTATLSCELSKAAP--VTWKKGPKTLQSGDKYVLRQDGAVCGL 3661
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
I + D G+Y+C G++ +A L + R +P F + L + E TEG + L
Sbjct: 3662 QIHGLTMADAGEYSCVC----GQEKTSATLTV--RGLPAKFIEDL-RSQEATEGATAILR 3714
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
++ + P+ W K + + + LQ++ ++ D G Y+
Sbjct: 3715 CELSKAAPVE--WRKGSETLKDGDRYTLRQDGAVCELQIRGLAVVDTGTYSL-------- 3764
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
P F + L +EG L C + + P+ +W K ++ D
Sbjct: 3765 --------------PTKFTEGLRNEEATEGTMATLRCQMSKAAPV--EWRKGSETLRDGD 3808
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
R S L+ + +T D+G+Y C S T K
Sbjct: 3809 RYSLRQDGAMCELQIRGLTIEDSGEYTCVCGQEKTSATLSVKALPPR------------- 3855
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F+ + +S E T AT ++ V+W KG L GGR + Q G
Sbjct: 3856 -----FIEDLRSQEATEGTMATLRCQMS--KAAPVEWRKGS-ETLGDGGRYSLRQNGAVC 3907
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ----VNERKKQEKIEG---DLRAMLKK 1787
+L+I D D+G Y CV + NV + + + QE EG LR + K
Sbjct: 3908 ELQIHDLAVEDTGEYSCVCGQEKTSATLNVKALPPRFIEDLRSQEATEGTMATLRCQMSK 3967
Query: 1788 TPVLKKGAGEE 1820
++ G E
Sbjct: 3968 AAPVEWRKGSE 3978
Score = 138 bits (348), Expect = 1e-32
Identities = 138/561 (24%), Positives = 227/561 (40%), Gaps = 3/561 (0%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+ T G A+L+CQ++ V W KG LR Y + V L + +D D+G+
Sbjct: 3952 EATEGTMATLRCQMSKAAP--VEWRKGSETLRDGGRYSLRQDGAVCELQIHDLDVEDAGQ 4009
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y C G+ +S LTV LPP F+ L+ + T G V C +S + +V W
Sbjct: 4010 YSCVC----GQEKTSAVLTVDA--LPPKFTEGLKKEEATEGTMVTLRCQMS--KEATVEW 4061
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K + L DG + L I AG+YSC SA+ S + +
Sbjct: 4062 RKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTSATLSVKAL----- 4116
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP F L +A G A C ++ P++ W K ++ +R G Y + L
Sbjct: 4117 -PPRFIEDLRSQEATEGTMATLRCQMSKAAPVE--WRKGSKTLRDGDRYSLRQDGAMCEL 4173
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN--SFR 902
I + DTG Y+C G++ +A L++K P ++ + ++ EG+ S R
Sbjct: 4174 QICDLAVEDTGDYSCVC----GQEKTSATLSVKA---PQVVFQQPLQNLQAEEGSMASLR 4226
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
E V + ++ W K +E+ E + L ++ DAG Y+C +
Sbjct: 4227 CELSVPNA---AMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQ- 4282
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
T+S + P F + L V EG +L C + E + ++W K ++ P
Sbjct: 4283 -----TTSATLMVTAAPVRFLRELQAQDVDEGATARLRCEL-SREAVSVEWRKGSLQLFP 4336
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ TA L V + DAG+Y C AG S ++++
Sbjct: 4337 CAKYQMVQEGTTAELLVHGVEQEDAGEYTCD----AGHTQSIARLSVRAP---------- 4382
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVG-GDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
K F ++ QS TA ++ +P V+W K + +L+ G + + ++G
Sbjct: 4383 ----KPKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQWLK-EGVELHVGSKYEMRRQG 4437
Query: 1620 DEAKLEIRDTTKTDSGLYRCV 1682
+L I D+G Y C+
Sbjct: 4438 AVCELLIHGLEAKDTGEYACL 4458
Score = 136 bits (342), Expect = 7e-32
Identities = 139/563 (24%), Positives = 239/563 (42%), Gaps = 5/563 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAG-TPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
V+V G+S S +C L+ +P W G + + + + TL +D+
Sbjct: 2901 VEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDA 2960
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GE + SV ++S L ++E+ P ++ L D + T+G V+ C +S + SV
Sbjct: 2961 GEVVF----SVLGLTSKASLIIRER--PVDITKPLEDQRTTLGEDVMLSCELSRAGT-SV 3013
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W KDG+ ++ A L + + +G+Y+C ++ S+A+L + E
Sbjct: 3014 RWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCETE----ASKSTAKLCVEE 3069
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
N F LA + A F C + V W K E+R+ G + S +
Sbjct: 3070 KANR--FTEELADLQVEEKGRAVFTCKTEHPASV-VTWRKGLLELRASGKHVPSQEGLTL 3126
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET---EGN 893
LTI +++ D+ YTC ++G+ A+L + + + ++ E +E+T EG+
Sbjct: 3127 KLTINALERTDSDTYTC----DIGQARTQARLLVHGQKV------RVIEDLEDTAVQEGS 3176
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNAL-LLQVKKASMGDAGLYTCKV 1070
S + R+A + V W+ + +H EIT + +L +++ ++ D+G V
Sbjct: 3177 SAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGT----V 3232
Query: 1071 SNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
+AG ++++ + E KP +F + LT VTV+EGE L L C + ++W K G+
Sbjct: 3233 YFEAGDQRTSAALRVTE--KPSIFSRPLTDVTVTEGEDLTLVCETTTVDS-SVRWTKDGK 3289
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
++PS RC S A L T D G Y C+ + S +
Sbjct: 3290 TLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHAL---------- 3339
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
+ F + + V E AT + P V+W G L + +
Sbjct: 3340 --------PVRFRESLKDVEVPEGKAATLRCVLSSVAAP-VEWRHGD-DVLKSSNKYSLR 3389
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRC 1679
Q+G +L IRD DSG Y C
Sbjct: 3390 QEGAVLELVIRDLQPQDSGQYSC 3412
Score = 135 bits (340), Expect = 1e-31
Identities = 145/552 (26%), Positives = 231/552 (41%), Gaps = 1/552 (0%)
Frame = +3
Query: 27 SASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAE 206
S L C P+ V WYK DT L P+ +KM +A L ++ D+G Y C+A
Sbjct: 2641 SVVLSCDFRPAPK-AVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQA- 2698
Query: 207 NSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRP 386
G SS +TV+ +++ + + L+D + V F C +S + + W +G P
Sbjct: 2699 ---GSAQSSAEVTVEAREV--TVIQPLQDAEAMEEGRVCFSCELSHKDE-DIEWSLNGTP 2752
Query: 387 LKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFD 566
L + + S + TL + ++ G + AT+P S SARL++ +G+ P F
Sbjct: 2753 LYNDSFHEISHEGCLHTLVLKSVRQADTG--TVCATSP--KVSVSARLVV-KGK-PVVFL 2806
Query: 567 IPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVD 746
L V A + +C V+ + +V W KD E+ Y + + LT+ +
Sbjct: 2807 KALDDVSAEERGTLTLQCEVSDPE-ARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLS 2865
Query: 747 KGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGS 926
D G YTC +VG +++++ + + TK+L +TVE EG S E ++
Sbjct: 2866 HEDAGLYTC----QVGSKETQSKVSVHD--LHVGITKRL-KTVEVLEGESCSFECVLSHE 2918
Query: 927 QPISVA-WYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTS 1103
P A W + + + + L VK A++ DAG V A
Sbjct: 2919 SPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKA---- 2974
Query: 1104 SIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFS 1283
S++I+E +P + L + GE + LSC + ++WLK G+ I+ S +
Sbjct: 2975 SLIIRE--RPVDITKPLEDQRTTLGEDVMLSCEL-SRAGTSVRWLKDGKAIRKSQKYDLL 3031
Query: 1284 FANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLF 1463
AVL + + D+G+Y C+ A T+K V
Sbjct: 3032 SEGTRAVLVVRKASLKDSGEYTCETE--ASKSTAKLCVEEKANR---------------- 3073
Query: 1464 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIR 1643
F E ++V EK A F K P V W KG +L G+ Q+G KL I
Sbjct: 3074 FTEELADLQVEEKGRAVFTCKT-EHPASVVTWRKG-LLELRASGKHVPSQEGLTLKLTIN 3131
Query: 1644 DTTKTDSGLYRC 1679
+TDS Y C
Sbjct: 3132 ALERTDSDTYTC 3143
Score = 134 bits (338), Expect = 2e-31
Identities = 155/615 (25%), Positives = 233/615 (37%), Gaps = 12/615 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFR-NNVATLVFNQVDSNDSGE 188
V G SA C++A V W+ T L ++ + L Q+ DSG
Sbjct: 3172 VQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGT 3231
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
A G+ +S L V E+ P FSR L DV T G + C + + SV W
Sbjct: 3232 VYFEA----GDQRTSAALRVTEK--PSIFSRPLTDVTVTEGEDLTLVCETTTVDS-SVRW 3284
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
KDG+ L+ Q S A L I T G+Y C IG ASSS+ I+
Sbjct: 3285 TKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCE----IGGASSSS--IVRVHA 3338
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
P F L V+ G++A C V + V W + ++S Y + L
Sbjct: 3339 LPVRFRESLKDVEVPEGKAATLRC-VLSSVAAPVEWRHGDDVLKSSNKYSLRQEGAVLEL 3397
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
I + D+GQY+C G + +A L +K F KL E TEG + L
Sbjct: 3398 VIRDLQPQDSGQYSC----SFGDQTTSATLTVKTS--SAQFVGKLRNK-EATEGTTVTLR 3450
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+ P+ W K + + LQ+ + DAG Y+C + S
Sbjct: 3451 CELTKEAPVE--WKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCGQEKTS 3508
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
A T ++ F + L +EG+ L C + + P+ +W K ++ D
Sbjct: 3509 ATLTVKALLVH------FVRRLRSKEATEGDTTTLQCELSKAAPV--EWRKGTETLRDGD 3560
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
R S L+ + +T ADAG+Y+C G + + + +T
Sbjct: 3561 RYSLKQDGAVCELQIRSLTIADAGEYLC----TCGQEKTSATLTVRALPAK--------- 3607
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F ++ E TTAT ++ V W KG + L G + + Q G
Sbjct: 3608 -----FKDSLKNEEATEGTTATLSCEL--SKAAPVTWKKGP-KTLQSGDKYVLRQDGAVC 3659
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV--------NERKKQEKIEGD---LRA 1775
L+I T D+G Y CV G+ +++ L V + + QE EG LR
Sbjct: 3660 GLQIHGLTMADAGEYSCVC----GQEKTSATLTVRGLPAKFIEDLRSQEATEGATAILRC 3715
Query: 1776 MLKKTPVLKKGAGEE 1820
L K ++ G E
Sbjct: 3716 ELSKAAPVEWRKGSE 3730
Score = 133 bits (335), Expect = 4e-31
Identities = 138/556 (24%), Positives = 225/556 (40%), Gaps = 2/556 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK G SA+L C++A + V+W+K KL ++ ++ LV Q D+G
Sbjct: 1609 VKAEAGASATLSCEVAQA-QTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAG 1667
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR-DVQETVGLPVVFECAVSGSEPISV 362
EY C A G S L V E KL + +Q +V+ G C V+ ++ V
Sbjct: 1668 EYSCEA----GGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQT-EV 1722
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+WFKDG+ L ++ L + Q ++ AG+YSC A G RL + E
Sbjct: 1723 TWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEA----GGQKLFFRLDVAE 1778
Query: 543 GRNPPFFDIPL-APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
+ + + V A G SA C V Q +V W KD +++ S ++ S
Sbjct: 1779 PKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQT-EVTWFKDGKKLSSSSKVRVEASGCS 1837
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L + +V K D G+Y+C A + K S + E IP +++ V+E E +
Sbjct: 1838 RRLVVQQVGKADAGEYSCEARGQ--KLSFRLDVAEAESQIPERPSRREPLVVKEHE--TI 1893
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L +A +V W K+ VEI + E T + L V+ A + D+ +Y+C+V +
Sbjct: 1894 ILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDSAIYSCRVGKE 1953
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
++ + F + L PV G + L C + E + W +++
Sbjct: 1954 G------QDFPVQVEEVAAKFSKPLEPVEGELGGTVMLVCEL-SPEQAEVVWRCGNTQLR 2006
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
P R + L + + DA +YVC++ + D + +++T
Sbjct: 2007 PGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRD----DRTSARLT------------- 2049
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V + F S ++ E ATF V V W K QL + + + G
Sbjct: 2050 VKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSD-AGVTWYK-DGMQLQPSEKFVMVESG 2107
Query: 1620 DEAKLEIRDTTKTDSG 1667
L I T D+G
Sbjct: 2108 ASRSLTILGLTLEDAG 2123
Score = 130 bits (326), Expect = 5e-30
Identities = 138/576 (23%), Positives = 230/576 (39%), Gaps = 2/576 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK G SA+L C++A + V+W+K KL ++ ++ LV Q D+G
Sbjct: 1701 VKAEAGASATLSCEVAQA-QTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAG 1759
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR-DVQETVGLPVVFECAVSGSEPISV 362
EY C A G L V E KL + +Q +V+ G C V+ ++ V
Sbjct: 1760 EYSCEA----GGQKLFFRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQT-EV 1814
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+WFKDG+ L ++ L + Q ++ AG+YSC A S RL + E
Sbjct: 1815 TWFKDGKKLSSSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQ----KLSFRLDVAE 1870
Query: 543 GRNP-PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
+ P P+ E+ + V W KD EIR ++ + L ++
Sbjct: 1871 AESQIPERPSRREPLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDT 1930
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
LT+ D+ Y+C VGK+ + ++E + F+K L E VE G +
Sbjct: 1931 HTLTVRGAQVLDSAIYSC----RVGKEGQDFPVQVEE--VAAKFSKPL-EPVEGELGGTV 1983
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L ++ Q V W N ++ P ++T + L V DA Y C+ +D
Sbjct: 1984 MLVCELSPEQA-EVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDD 2042
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
SA T +K P+ F L+ + EG+ C V S+ + W K G +++
Sbjct: 2043 RTSARLT----VKVPRVVK-FTSGLSAMVAEEGQEATFQCVVSPSDA-GVTWYKDGMQLQ 2096
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
PS++ + + L +T DAG +A + S + +
Sbjct: 2097 PSEKFVMVESGASRSLTILGLTLEDAGQVTVEAEGASSSAALRVR--------------- 2141
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
+ + F + + V E+T+ T ++ P P VKWT+ L + I +G
Sbjct: 2142 ---EAPVLFKKKLEPQTVEERTSVTLEVEL-TRPWPEVKWTRNA-AVLTPSENVEIRAEG 2196
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
L +R D G + C + + + NV ++
Sbjct: 2197 ARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMR 2232
Score = 124 bits (312), Expect = 2e-28
Identities = 144/574 (25%), Positives = 232/574 (40%), Gaps = 6/574 (1%)
Frame = +3
Query: 36 LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSV 215
L+CQ++ V W+KG +L+ Y++ LV N V D Y C A
Sbjct: 2465 LECQVSRA-SAQVRWFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDA---- 2519
Query: 216 GEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKD 395
G V +S V+EQ + + R L+D+ P FEC S W L+
Sbjct: 2520 GNVKTSAQFFVEEQSI--TIVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQA 2577
Query: 396 GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPL 575
G N+ V L + +T + G T IG + SSA+L++++ P PL
Sbjct: 2578 GGNVGLEQDGTVHRLTLHKTCSTMTGPVHFT----IGKSRSSAQLVVSD--IPVVLTRPL 2631
Query: 576 APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGD 755
P +S C P V W KD+ + ++++ A L IL++ D
Sbjct: 2632 EPKAGRELQSVVLSCDFR-PAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPAD 2690
Query: 756 TGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPI 935
G Y C A G +A++ ++ R + + +E +E EGRV S +
Sbjct: 2691 AGVYRCQA----GSAQSSAEVTVEAREVTVIQPLQDAEAME---------EGRVCFSCEL 2737
Query: 936 S-----VAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
S + W N ++ + EI+ + L +K D G C S +
Sbjct: 2738 SHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSVRQADTGT-VCATSPKVS---VS 2793
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSF 1280
+ +V+K KP VF + L V+ E L L C V E R+ W K G E+ PSD+ F
Sbjct: 2794 ARLVVK--GKPVVFLKALDDVSAEERGTLTLQCEVSDPE-ARVVWRKDGVELGPSDKYDF 2850
Query: 1281 SFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKL 1460
G L D++ DAG Y C+ GS ++SKV+ D +
Sbjct: 2851 LHKAGARGLTVHDLSHEDAGLYTCQ----VGSKETQSKVSVH--------------DLHV 2892
Query: 1461 FFVSEPQSIRVVEKTTATFIAKVGGD-PIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
+++ V+E + +F + + P WT G + + G ++G + L
Sbjct: 2893 GITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVG-GKTVGGSGHFHAVRQGRKYTLT 2951
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
++D +D+G V F+ G + S +L + ER
Sbjct: 2952 VKDAALSDAGE---VVFSVLG-LTSKASLIIRER 2981
Score = 122 bits (305), Expect = 1e-27
Identities = 113/470 (24%), Positives = 195/470 (41%), Gaps = 5/470 (1%)
Frame = +3
Query: 291 DVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFA 470
+V+ G C V+ ++ V+WFKDG+ L ++ L + Q ++ A
Sbjct: 872 EVKAEAGASATLSCEVAQAQT-EVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADA 930
Query: 471 GQYSCTATNPIGSASSSARLILTEGRNPPFFDIPL-APVDAVVGESADFECHVTGTQPIK 647
G+YSC A G S RL + E + + + V A G SA C V Q +
Sbjct: 931 GEYSCEA----GGQKLSFRLDVAEPKMVFAKEQQARSEVKAEAGASATLSCEVAQAQ-TE 985
Query: 648 VAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIK 827
V W KD +++ S ++ S L + + K D G+Y+C E G + +L++
Sbjct: 986 VTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSC----EAGGQKLSFRLDVT 1041
Query: 828 ERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNN 1007
E + + ++ V+ GNS L VA +Q V W+K+ ++ ++ +
Sbjct: 1042 EPKLVFAKEQQARSEVKAEVGNSATLSCEVAQAQ-TEVTWFKDGKKLSSSSKVRMEASGC 1100
Query: 1008 ALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEF 1184
+ L V++A DAG Y+C +AG + + + EPK +Q + V G
Sbjct: 1101 SRRLVVQQAGKADAGEYSC----EAGGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGNS 1156
Query: 1185 LQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASN 1364
LSC V ++ + W K G+++ S + + + L + KADAG+Y C+A
Sbjct: 1157 ATLSCEVAQAQ-TEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGG 1215
Query: 1365 VAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS---IRVVEKTTATFIAKVGG 1535
S + KL F E Q+ ++ +AT +V
Sbjct: 1216 QKLS------------------FHLDVTEPKLVFAKEQQAHSEVKAEAGASATLSCEV-A 1256
Query: 1536 DPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVA 1685
V W K ++L+ ++ + G +L ++ K D+G Y C A
Sbjct: 1257 QAQTEVTWFK-DGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEA 1305
Score = 112 bits (279), Expect = 1e-24
Identities = 78/303 (25%), Positives = 132/303 (43%), Gaps = 19/303 (6%)
Frame = +3
Query: 264 PPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPN-IQTSFLDNVATL 440
PP F +L D +G V C V+G+ VSW+KDG+P++ P+ I D TL
Sbjct: 6235 PPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTL 6294
Query: 441 NIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFEC 620
+ +GQY C A + G+AS+ ++++ + PP F + V GE A C
Sbjct: 6295 ILDNLTGIDSGQYMCFAASAAGNASTLGKILV---QVPPRFVNKVRATPFVEGEDAQITC 6351
Query: 621 HVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL--KVDKGDTGQYTCYAVNEVG 794
V G ++ W KD + G Y++ S L ++ K D G Y C VN +G
Sbjct: 6352 TVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLG 6411
Query: 795 KDSCTAQLNI------------KERLIPP-SFTKKLSETVEETE---GNSFRLEGRVAGS 926
+L + +E+++ + T+E+ + G+ + + + G
Sbjct: 6412 STRGGGELYMQSPALRARDQHHREQIVAAVEGAPSMQVTIEDVQVQVGDMAQFDAVIEGH 6471
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS 1106
P V WYK + ++ +A L + + DAG+YTC +N G LC +
Sbjct: 6472 PPPIVTWYKGSTQLTSSARLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKAE 6531
Query: 1107 IVI 1115
+++
Sbjct: 6532 LLV 6534
Score = 110 bits (276), Expect = 3e-24
Identities = 103/415 (24%), Positives = 161/415 (38%), Gaps = 39/415 (9%)
Frame = +3
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
P F P A V +V G+ A C + G V+W KD + + +G ++++ + LT
Sbjct: 9 PRFLTRPKAFVVSV-GKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLT 67
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKER-----LIPPSFTKKLSETVEETEGNS 896
IL + GD+GQY C A N +G+ L + P + S V E +
Sbjct: 68 ILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADAT 127
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHP--TANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
FR RV GS +V+W K+ + P + + + L+++ A D G Y +
Sbjct: 128 FRC--RVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRA 185
Query: 1071 SNDAGSALCTSSIVIKE-------------------------------PKKPPVFDQHLT 1157
N GSA +++V+ P PP
Sbjct: 186 ENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPP--GAGTR 243
Query: 1158 PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR-CSFSFANGTAVLEFKDVTKAD 1334
TV+EG+ +LSC V G W K G+ + R + VL+ ++D
Sbjct: 244 TCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSD 303
Query: 1335 AGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTAT 1514
G Y C ASN+ G S V + + F Q + V EK +AT
Sbjct: 304 RGLYTCTASNLVGQTYSSVLVVVR--------------EPTVPFKKRLQDLEVREKESAT 349
Query: 1515 FIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRC 1679
F +V P W K + R L + I ++G E +L +R+ + D +Y C
Sbjct: 350 FQCEV-AQPATEAAWFKEETR-LWASAKYDIEEEGTERRLTVRNVSADDDAVYIC 402
Score = 104 bits (260), Expect = 2e-22
Identities = 116/494 (23%), Positives = 191/494 (38%), Gaps = 40/494 (8%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRP--TATYKMHFRNNVATLVFNQVDSND 179
++V G A+ +C++ G+P+ VSW K +L P ++ + L D
Sbjct: 118 IRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRD 177
Query: 180 SGEYICRAENSVGEVSSSTFLTVQ---EQKLPPSFS--------RQLRDVQETVGLP--- 317
G Y RAEN +G S++ L V E PP S +Q R+ G+P
Sbjct: 178 GGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSP 237
Query: 318 ---------------VVFECAVSGSEPISVSWFKDGRPLKDGPN--IQTSFLDNVATLNI 446
C V+G W KDG+ + +G + +N L I
Sbjct: 238 PGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENF-VLKI 296
Query: 447 FQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHV 626
+S G Y+CTA+N +G SS +++ E P F L ++ ESA F+C V
Sbjct: 297 LFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPTVP--FKKRLQDLEVREKESATFQCEV 354
Query: 627 TGTQP-IKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDS 803
QP + AW K+ + + Y I LT+ V D Y C ++
Sbjct: 355 --AQPATEAAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYIC--------ET 404
Query: 804 CTAQLNIKERLIPPSFTKKLSETVEETEGNS--FRLEGRVAGSQPISVAWYKNNVEIHPT 977
+ E + + T+KL G++ F +E V V W +N E+
Sbjct: 405 TEGSRTVAELSVQGNLTRKLPRKTAVRTGDTAIFWVELAVPEG---PVRWLRNQEEMVAG 461
Query: 978 ANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT 1157
IT + L + + ++ D G +V+ +G T+ + P++PP++
Sbjct: 462 GRVAITAEGTCHTLTIFQCTLEDMG----EVAFVSGGCRTTTQFCVSAPRRPPLYPP-AD 516
Query: 1158 PVTVSEGE---FLQLSCHVRGSEPIRIQ-WLKAGREIKPSDRCSFSFANGTAVLEFKDVT 1325
PV ++ E L S G P+ I ++ R++ A A EF
Sbjct: 517 PVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHEAGWLATTEFTITG 576
Query: 1326 KADAGDYVCKASNV 1367
A+ GD+ + S +
Sbjct: 577 VAEEGDFQFRVSAI 590
Score = 103 bits (257), Expect = 5e-22
Identities = 121/503 (24%), Positives = 187/503 (37%), Gaps = 36/503 (7%)
Frame = +3
Query: 267 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNI 446
P F + + +VG C + G+ VSW KD +P++ G + + +V L I
Sbjct: 9 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTI 68
Query: 447 FQTDRSFAGQYSCTATNPIGSASSSARL-ILTEG---RNPPFFDIPLAPVDAVVGESADF 614
+GQY C A N IG A ++ L + +EG P F + + G A F
Sbjct: 69 LDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATF 128
Query: 615 ECHVTGTQPIKVAWAKDNREI--RSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNE 788
C V G+ V+W+KD R + + ++ S+ L I D G Y A N
Sbjct: 129 RCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENP 188
Query: 789 VGKDSCTAQL---------------------NIKERL-------IPPSFTKKLSETVEET 884
+G S A L ++++R IPPS + T T
Sbjct: 189 LGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVT 248
Query: 885 EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNA--LLLQVKKASMGDAGLY 1058
EG RL V G W K+ ++ + +++ +L++ D GLY
Sbjct: 249 EGKHARLSCFVTGEPKPETVWKKDG-QLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLY 307
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWL 1238
TC SN G + +V++EP P F + L + V E E C V W
Sbjct: 308 TCTASNLVGQTYSSVLVVVREPTVP--FKKRLQDLEVREKESATFQCEV-AQPATEAAWF 364
Query: 1239 KAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXX 1418
K + S + L ++V+ D Y+C+ + GS T
Sbjct: 365 KEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYICETTE--GSRT------------ 410
Query: 1419 XXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR 1598
V G L P+ V TA F ++ P V+W + + ++ GGR
Sbjct: 411 ----VAELSVQGNL-TRKLPRKTAVRTGDTAIFWVELAVPEGP-VRWLRNQ-EEMVAGGR 463
Query: 1599 IFIHQKGDEAKLEIRDTTKTDSG 1667
+ I +G L I T D G
Sbjct: 464 VAITAEGTCHTLTIFQCTLEDMG 486
Score = 103 bits (256), Expect = 6e-22
Identities = 78/302 (25%), Positives = 126/302 (41%), Gaps = 20/302 (6%)
Frame = +3
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNY-QISYLENSAHL 728
PP F+ LA A +GE+ C VTGT V+W KD + + ++ I + S L
Sbjct: 6235 PPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTL 6294
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
+ + D+GQY C+A + G S ++ ++ +PP F K+ T EG ++
Sbjct: 6295 ILDNLTGIDSGQYMCFAASAAGNASTLGKILVQ---VPPRFVNKVRAT-PFVEGEDAQIT 6350
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITF--KNNALLLQVKKASMGDAGLYTCKVSNDA 1082
V G+ + WYK+ + P + ++ L+L ++ AS D G Y C++ N
Sbjct: 6351 CTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRL 6410
Query: 1083 GSALCTSSIVIKEP-----------------KKPPVFDQHLTPVTVSEGEFLQLSCHVRG 1211
GS + ++ P + P + V V G+ Q + G
Sbjct: 6411 GSTRGGGELYMQSPALRARDQHHREQIVAAVEGAPSMQVTIEDVQVQVGDMAQFDAVIEG 6470
Query: 1212 SEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS 1391
P + W K ++ S R S T L DV DAG Y C A+N G K+
Sbjct: 6471 HPPPIVTWYKGSTQLTSSARLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKA 6530
Query: 1392 KV 1397
++
Sbjct: 6531 EL 6532
Score = 102 bits (253), Expect = 1e-21
Identities = 114/453 (25%), Positives = 188/453 (41%), Gaps = 22/453 (4%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G +A L+C+L+ + V W KG +L P A Y+M A L+ + V+ D+GEY
Sbjct: 4306 VDEGATARLRCELS-REAVSVEWRKGSLQLFPCAKYQMVQEGTTAELLVHGVEQEDAGEY 4364
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEP-ISVSW 368
C A G S L+V+ K P F L+ ++ G C +S +EP V W
Sbjct: 4365 TCDA----GHTQSIARLSVRAPK--PKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQW 4418
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
K+G L G + V L I + G+Y+C +G + A L + E
Sbjct: 4419 LKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTGEYACL----VGGQKTLASLRVKE-- 4472
Query: 549 NPPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL-ENS 719
P I VD V E +F C V+ V W ++S +++ L +
Sbjct: 4473 --PEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLADGC 4530
Query: 720 AHLTILK-VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
H+ LK V D G + + VG S +AQL ++ +P + + V+ +EG
Sbjct: 4531 THVLQLKGVTLEDAGTVSFH----VGGLSSSAQLTVR---VPEVTVLEPLKDVQLSEGQD 4583
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNAL-LLQVKKASMGDAGLYTCKVS 1073
R++ + W V + +IT + L LL + K ++ DAG T +V
Sbjct: 4584 AHFRCRLSRASGQEARWALGGVPLQCNEMNDITVEQGTLYLLTLHKVTLEDAGTITLQVG 4643
Query: 1074 NDAGSA--LCTSSIVIKEPKK-------PPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIR 1226
+ + A T++ V++ + +F+ L+ V+ +L V SE +
Sbjct: 4644 SCSSEAQLKVTANTVLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVE 4703
Query: 1227 IQWLKAG-------REIKPSDRCSFSFANGTAV 1304
+ + + G + +KP D C +F G V
Sbjct: 4704 VVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVV 4736
Score = 100 bits (249), Expect = 4e-21
Identities = 87/323 (26%), Positives = 139/323 (43%), Gaps = 10/323 (3%)
Frame = +3
Query: 795 KDSCTAQLNIKERLI-PPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNN--VE 965
K+ C Q + + + PP F ++L++ E G + +L RV G+ V+WYK+ VE
Sbjct: 6219 KEICGIQQRLAQPVWRPPEFEEELADCTAEL-GETVKLACRVTGTPKPIVSWYKDGKPVE 6277
Query: 966 IHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFD 1145
+ P + I + + L + + D+G Y C ++ AG+A I+++ P P F
Sbjct: 6278 VDPH-HILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVP---PRFV 6333
Query: 1146 QHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSF--SFANGTAVLEFKD 1319
+ EGE Q++C V G+ +I+W K G + P +R +G VL +
Sbjct: 6334 NKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQA 6393
Query: 1320 VTKADAGDYVCKASNVAGSDTSKSKV-----TXXXXXXXXXXXXXXXVDGKLFFVSEPQS 1484
+K D G Y C+ N GS ++ V+G +
Sbjct: 6394 ASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEGAPSMQVTIED 6453
Query: 1485 IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDS 1664
++V A F A + G P P V W KG QL R+ Q G L + D D+
Sbjct: 6454 VQVQVGDMAQFDAVIEGHPPPIVTWYKGS-TQLTSSARLSQRQDGTTYSLVLTDVAPHDA 6512
Query: 1665 GLYRCVAFNKHGEIESNVNLQVN 1733
G+Y CVA N G++ L V+
Sbjct: 6513 GVYTCVANNAGGQVLCKAELLVH 6535
Score = 100 bits (249), Expect = 4e-21
Identities = 75/290 (25%), Positives = 114/290 (39%), Gaps = 23/290 (7%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHF----RNNVATLVFNQVDSNDSG 185
+G++ L C++ GTP+ VSWYK +P H + TL+ + + DSG
Sbjct: 6249 LGETVKLACRVTGTPKPIVSWYKDG---KPVEVDPHHILIEDPDGSCTLILDNLTGIDSG 6305
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y+C A ++ G S+ + VQ +PP F ++R G C V G+ +
Sbjct: 6306 QYMCFAASAAGNASTLGKILVQ---VPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIR 6362
Query: 366 WFKDGRPLKDGPNIQ--TSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL--- 530
W+KDG L G + V L I + G Y C N +GS L
Sbjct: 6363 WYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQ 6422
Query: 531 --------------ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDN 668
I+ P + + V VG+ A F+ + G P V W K +
Sbjct: 6423 SPALRARDQHHREQIVAAVEGAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTWYKGS 6482
Query: 669 REIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQL 818
++ S + L + V D G YTC A N G+ C A+L
Sbjct: 6483 TQLTSSARLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKAEL 6532
Score = 94.0 bits (232), Expect = 4e-19
Identities = 137/586 (23%), Positives = 224/586 (38%), Gaps = 7/586 (1%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ V ++ L +A V+W K ++R + ++ + TL DS
Sbjct: 1884 PLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDS 1943
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
Y CR VG+ VQ +++ FS+ L V+ +G V+ C +S E V
Sbjct: 1944 AIYSCR----VGKEGQD--FPVQVEEVAAKFSKPLEPVEGELGGTVMLVCELS-PEQAEV 1996
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W L+ G Q + TL + A +Y C + + +SARL +
Sbjct: 1997 VWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDD----RTSARLTVKV 2052
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
R F L+ + A G+ A F+C V V W KD +++ + + S
Sbjct: 2053 PRVVKFTS-GLSAMVAEEGQEATFQC-VVSPSDAGVTWYKDGMQLQPSEKFVMVESGASR 2110
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLS-ETVEETEGNSF 899
LTIL + D GQ T E S +A L ++E P F KKL +TVEE S
Sbjct: 2111 SLTILGLTLEDAGQVTV----EAEGASSSAALRVRE--APVLFKKKLEPQTVEER--TSV 2162
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
LE + P V W +N + P+ N EI + L ++ D G + C+ +D
Sbjct: 2163 TLEVELTRPWP-EVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADRGFFGCETPDD 2221
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
A ++ +++ + + L V E + + +E + W + G ++
Sbjct: 2222 KTQA--KLNVEMRQVR----LVRGLQEVEAKEQGTASMDVELSHAE-VEGSWTRDGLRLQ 2274
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
P +C + +L + D+G +A V S
Sbjct: 2275 PGPKCHLAVQGPVHILTLSALQPQDSGLVAFRAEGVHTS--------------------- 2313
Query: 1440 XXVDGKLFFVSEPQSI-RVVEKTTATFIAKVG-----GDPIPNVKWTKGKWRQLNQGGRI 1601
+L P S RV++ AT KV P+ +V+W K +L G I
Sbjct: 2314 ----ARLIVTELPVSFTRVLQDVVATQKEKVTLECELSRPV-DVRWLK-DGVELRAGKAI 2367
Query: 1602 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
I +G L I D G+Y C A + +++ +L+V R
Sbjct: 2368 GIVAQGTCRSLVIYRCETGDQGVYVCDAL----DAQTSASLRVQGR 2409
Score = 94.0 bits (232), Expect = 4e-19
Identities = 121/548 (22%), Positives = 196/548 (35%), Gaps = 96/548 (17%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKM-HFRNNVATLVFNQVDSNDSGEYI 194
VGD L+C LA ++ W K +L Y + ++ +L+ + DSG Y
Sbjct: 5133 VGDVLRLECVLATKTDMRACWLKDGIELTDGRHYHIDQLKDGTCSLLVTGLAPTDSGRYT 5192
Query: 195 CRAENSVGEVSSSTFLTVQEQK----------LPPSFSRQLRDVQET--------VGLPV 320
C+ G VS S + V + L +F R R + +
Sbjct: 5193 CQVSTKSGRVSHSACVVVSGTESEAESSSGGELDDAFRRAARRLHRLFRTKSPAELSEEE 5252
Query: 321 VFECAVSG----SEPISVSWFKDGR--------PLKDGPNIQTSFLDNVATLNIFQTDRS 464
+F A G EP +++ L + T F + AT+ I + S
Sbjct: 5253 LFLSADEGPGEPEEPADWQTYREDENFVCIRFESLAEARQAVTCFRNMFATMGI-GVEIS 5311
Query: 465 FAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPV--------DAVVGESADFEC 620
Q IG + + + + P APV D G F+C
Sbjct: 5312 LGEQGPRGVEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDC 5371
Query: 621 HVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH-LTILKVDKGDTGQYTCYAVNEVGK 797
VTG V W KD + + +Y I+ + H L I V D G Y C A N +G
Sbjct: 5372 VVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGV 5431
Query: 798 DSCTAQLNI----------------------------KERLIPPSFTKKLSETVEETEGN 893
S A+L + +E+ S +L + +EE +
Sbjct: 5432 SSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGTESDEGQLPQVLEELKDL 5491
Query: 894 SF-------RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAG 1052
+ + +V G + W+K+ + + + +T K L++ + D+G
Sbjct: 5492 QVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTREDSG 5551
Query: 1053 LYTCKVSNDAGSALCTSSIVIK---EPKKPPVFDQH-----------LTPVTVSEGEFLQ 1190
Y +SN G+A ++ ++++ EP++ P D H TP V G +
Sbjct: 5552 QYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSIT 5611
Query: 1191 LSCHVRGSEPIRIQWLKAGRE-----IKPSDRCSFSFANGTA--VLEFKDVTKADAGDYV 1349
S V G + WLK E I P D ++ A+ + L DV + G Y
Sbjct: 5612 FSVKVEGHPAPSVHWLKEEAEKGVLWIGP-DTPGYTMASSSKQHSLVLLDVGRQHQGTYT 5670
Query: 1350 CKASNVAG 1373
C A+N AG
Sbjct: 5671 CIATNPAG 5678
Score = 90.9 bits (224), Expect = 3e-18
Identities = 83/325 (25%), Positives = 122/325 (37%), Gaps = 57/325 (17%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHF-RNNVATLVFNQVDSNDSGEYIC 197
G S C + G P V W+K L Y ++ + L+ V D G Y C
Sbjct: 5364 GYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRC 5423
Query: 198 RAENSVGEVSSSTFLTVQ-----------------------------------EQKLPPS 272
AENS+G S+ L V+ ++ P
Sbjct: 5424 LAENSMGVSSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGTESDEGQLPQ 5483
Query: 273 FSRQLRDVQETVGLPVV-FECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIF 449
+L+D+Q G + F+ V G + WFKDG+PL +I+ + + TL I
Sbjct: 5484 VLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIV 5543
Query: 450 QTDRSFAGQYSCTATNPIGSASSSARLIL---TEGRNPPFFDI-----------PLAPVD 587
R +GQY+ +N +G+A SSARL++ +E P D+ P
Sbjct: 5544 SVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKK 5603
Query: 588 AVVGESADFECHVTGTQPIKVAWAKDNREI------RSGGNYQISYLENSAHLTILKVDK 749
G S F V G V W K+ E Y ++ L +L V +
Sbjct: 5604 VKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGR 5663
Query: 750 GDTGQYTCYAVNEVGKDSCTAQLNI 824
G YTC A N G+ C+A L+I
Sbjct: 5664 QHQGTYTCIATNPAGQALCSASLHI 5688
Score = 88.2 bits (217), Expect = 2e-17
Identities = 98/399 (24%), Positives = 156/399 (39%), Gaps = 70/399 (17%)
Frame = +3
Query: 129 FRNNVATLVFN-QVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLP--------PSFSR 281
FRN AT+ ++ + G E +G+V+ + V K P P F
Sbjct: 5297 FRNMFATMGIGVEISLGEQGPR--GVEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLT 5354
Query: 282 QLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVA-TLNIFQTD 458
+L++ G P+ F+C V+G SV WFKDG+ L++ + + L I
Sbjct: 5355 ELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVV 5414
Query: 459 RSFAGQYSCTATNPIGSASSSARLILT--------------------------------- 539
+ G Y C A N +G +S+ A L +
Sbjct: 5415 PADMGVYRCLAENSMGVSSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGT 5474
Query: 540 ---EGRNPPFF----DIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQ 698
EG+ P D+ +AP + A F+ V G K+ W KD + + + + +
Sbjct: 5475 ESDEGQLPQVLEELKDLQVAPGTRL----AKFQLKVKGYPAPKLYWFKDGQPLTTSDHIR 5530
Query: 699 ISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQL--------------NIKERL 836
++ + L I+ V + D+GQY Y N VG +A+L ++ ERL
Sbjct: 5531 MTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERL 5590
Query: 837 IPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVE-----IHP-TANCEITF 998
+PP +K + + G+S +V G SV W K E I P T +
Sbjct: 5591 VPPRILEKFTPK-KVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMAS 5649
Query: 999 KNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVI 1115
+ L + G YTC +N AG ALC++S+ I
Sbjct: 5650 SSKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHI 5688
Score = 70.5 bits (171), Expect = 5e-12
Identities = 51/194 (26%), Positives = 70/194 (36%), Gaps = 19/194 (9%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKM--HFRNNVATLVFNQVDSNDSGEYI 194
G+ A + C + G P + WYK T L P Y+M R+ V LV D G Y
Sbjct: 6344 GEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYE 6403
Query: 195 CRAENSVGEVSSSTFLTVQEQKL-----------------PPSFSRQLRDVQETVGLPVV 323
C N +G L +Q L PS + DVQ VG
Sbjct: 6404 CELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEGAPSMQVTIEDVQVQVGDMAQ 6463
Query: 324 FECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPI 503
F+ + G P V+W+K L + +L + AG Y+C A N
Sbjct: 6464 FDAVIEGHPPPIVTWYKGSTQLTSSARLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNAG 6523
Query: 504 GSASSSARLILTEG 545
G A L++ G
Sbjct: 6524 GQVLCKAELLVHGG 6537
Score = 69.7 bits (169), Expect = 8e-12
Identities = 105/474 (22%), Positives = 184/474 (38%), Gaps = 25/474 (5%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++V +SA+ QC++A P +W+K +T+L +A Y + L V ++D
Sbjct: 340 LEVREKESATFQCEVA-QPATEAAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDA 398
Query: 186 EYICRA---ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
YIC +V E+S LT +KLP R G +F ++ E
Sbjct: 399 VYICETTEGSRTVAELSVQGNLT---RKLP-------RKTAVRTGDTAIFWVELAVPEG- 447
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
V W ++ + G + + TL IFQ G+ + + G ++ + +
Sbjct: 448 PVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVS----GGCRTTTQFCV 503
Query: 537 TEGRNPPFFDIPLAPVDAVVGESADFECHVT--------GTQPIKV-AWAKDNREIRSGG 689
+ R PP + P D VV A E VT G +P+ + + + R++ G
Sbjct: 504 SAPRRPPLYP----PADPVV--KAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKL---G 554
Query: 690 NYQISYLENSAHL-----TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT 854
Y S + L TI V + Q+ A+N G+ + L+P
Sbjct: 555 AYAWSRCHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYL-EFPGTMHLVPMLAV 613
Query: 855 KKLSETVEETEGNSFRLEGRVAGSQPISVA----WYKNNVEIHPTANCEITFKNNALLLQ 1022
K + VE EG G V S ++VA W+ + + ++ I +L
Sbjct: 614 KTPLKAVEAVEG------GEVTFSVDLTVASSGEWFLDGEALKASSIYVIRCDRTRHMLT 667
Query: 1023 VKKASMGDAGLYTCKVSNDAGSAL---CTSSIVIKEPKKPPVFDQHLTPVTVSEGEFL-Q 1190
+++ G V+N +++ +++ + K P + + E + L +
Sbjct: 668 IREVPARLHGAQLKFVANGIETSIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAE 727
Query: 1191 LSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVC 1352
LS + + WLK GRE+ + + G L +DV + DAG Y C
Sbjct: 728 LS-----DQAAAVTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYEC 776
Score = 68.9 bits (167), Expect = 1e-11
Identities = 92/404 (22%), Positives = 149/404 (36%), Gaps = 31/404 (7%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P V S +L+ +L P V W + L P+ ++ LV V D
Sbjct: 2153 PQTVEERTSVTLEVELT-RPWPEVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADR 2211
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G + C + + L V+ +++ R L++V+ + +S +E +
Sbjct: 2212 GFFGCETPDDKTQAK----LNVEMRQV--RLVRGLQEVEAKEQGTASMDVELSHAE-VEG 2264
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SW +DG L+ GP + V L + +G + A +SARLI+TE
Sbjct: 2265 SWTRDGLRLQPGPKCHLAVQGPVHILTLSALQPQDSGLVAFRAEG----VHTSARLIVTE 2320
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L V A E EC ++ +P+ V W KD E+R+G I
Sbjct: 2321 --LPVSFTRVLQDVVATQKEKVTLECELS--RPVDVRWLKDGVELRAGKAIGIVAQGTCR 2376
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I + + GD G Y C A++ +A L ++ R F + L+E E + +
Sbjct: 2377 SLVIYRCETGDQGVYVCDALDA----QTSASLRVQGRTYTLIFRRVLAEDAGEVKFVAEN 2432
Query: 903 LEGR---------VAGSQPI----------------------SVAWYKNNVEIHPTANCE 989
E R V +P+ V W+K VE+ E
Sbjct: 2433 AESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGGVELQSGPKYE 2492
Query: 990 ITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKE 1121
+ L + D YTC DAG+ ++ ++E
Sbjct: 2493 VVSDGLYRKLVINDVQPEDEDTYTC----DAGNVKTSAQFFVEE 2532
Score = 68.2 bits (165), Expect = 2e-11
Identities = 51/190 (26%), Positives = 76/190 (40%), Gaps = 1/190 (0%)
Frame = +3
Query: 1167 VSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDY 1346
VS G+ LSC + G+ + W K + ++ R + L D+ D+G Y
Sbjct: 20 VSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGDSGQY 79
Query: 1347 VCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAK 1526
VC+A N G + + + F+ P SIRV E ATF +
Sbjct: 80 VCRARNAIGEAFAAVGLRVDSEGTC--------AEQAPHFLLRPTSIRVREGADATFRCR 131
Query: 1527 VGGDPIPNVKWTK-GKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
VGG P P V W+K G+ + + + G+ + L IR D G Y A N G
Sbjct: 132 VGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGS 191
Query: 1704 IESNVNLQVN 1733
+ L V+
Sbjct: 192 ASAAAALVVD 201
Score = 56.2 bits (134), Expect = 9e-08
Identities = 85/401 (21%), Positives = 142/401 (35%), Gaps = 9/401 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHF-RNNVATLVFNQVDSNDS 182
V+++ G A +C+L+ W G L+ + + + L ++V D+
Sbjct: 4576 VQLSEGQDAHFRCRLSRASGQEARWALGGVPLQCNEMNDITVEQGTLYLLTLHKVTLEDA 4635
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G + VG SS L V + R L +V G +FEC +S E +
Sbjct: 4636 GTITLQ----VGSCSSEAQLKVTANTV----LRGLENVDALEGGEALFECQLSQPEVAAH 4687
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W D P+ ++ + +N L ++ Q SC T G +SA L +
Sbjct: 4688 TWLLDDEPVHTSEKVEVVYFEN--GLRHLLLLKNLKPQDSCRVTFLAGDVVTSAFLTVRA 4745
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIK-----VAWAKDNREIRSGGNYQISY 707
+P P DA V +D ++ P+ + + + S G +Q+ +
Sbjct: 4746 --------LPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCH 4797
Query: 708 -LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
L + + G T ++ AV G + P ET +
Sbjct: 4798 DLVPGPECVVDDLVPGKTYRFRVAAVGPAGAGEPVHLPQMAPAPAPAPAPAPAPETRQAV 4857
Query: 885 EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTC 1064
G LE VA V W+K I P + E+ + +L +K D G Y C
Sbjct: 4858 VGEDICLELEVAADGG-EVVWHKGTERIQPGGHFEVLSRGQRQMLVIKGFRTEDQGEYRC 4916
Query: 1065 -KVSNDAGSALCTSSIVIKEPKKPPVFDQ-HLTPVTVSEGE 1181
+ S T ++V+ V Q L P EG+
Sbjct: 4917 GPIQGLPSSGAATFNVVMTSGSGDEVPAQPSLPPEAAQEGD 4957
Score = 56.2 bits (134), Expect = 9e-08
Identities = 52/232 (22%), Positives = 94/232 (40%), Gaps = 11/232 (4%)
Frame = +3
Query: 1119 EPKKPPVFDQHLTPVTVSEGEFL-QLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANG 1295
E + P V ++ L + V+ G L + V+G ++ W K G+ + SD +
Sbjct: 5478 EGQLPQVLEE-LKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKT 5536
Query: 1296 TAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV----TXXXXXXXXXXXXXXXVDGKLF 1463
LE VT+ D+G Y SN G+ S +++ V ++
Sbjct: 5537 LHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRIL 5596
Query: 1464 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGK------WRQLNQGGRIFIHQKGDE 1625
P+ ++ ++ TF KV G P P+V W K + W + G + +
Sbjct: 5597 EKFTPKKVK--RGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPG-YTMASSSKQ 5653
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAML 1781
L + D + G Y C+A N G+ + +L ++ K+E+ E A++
Sbjct: 5654 HSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALI 5705
Score = 53.5 bits (127), Expect = 6e-07
Identities = 38/109 (34%), Positives = 51/109 (46%), Gaps = 7/109 (6%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+V VGD A + G P V+WYKG T+L +A +LV V +D+G
Sbjct: 6454 VQVQVGDMAQFDAVIEGHPPPIVTWYKGSTQLTSSARLSQRQDGTTYSLVLTDVAPHDAG 6513
Query: 186 EYICRAENSVGEVSSSTFLTVQ-EQKLPPS---FSRQLR---DVQETVG 311
Y C A N+ G+V L V KL + R+L DVQE +G
Sbjct: 6514 VYTCVANNAGGQVLCKAELLVHGGDKLDAENQVYRRKLHSFYDVQEEIG 6562
Score = 51.6 bits (122), Expect = 2e-06
Identities = 31/90 (34%), Positives = 47/90 (52%)
Frame = +3
Query: 1464 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIR 1643
F++ P++ V AT ++ G+P P+V W K + + + G R + Q GD +L I
Sbjct: 11 FLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDR-QPVEAGARFRLAQDGDVYRLTIL 69
Query: 1644 DTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
D DSG Y C A N GE + V L+V+
Sbjct: 70 DLALGDSGQYVCRARNAIGEAFAAVGLRVD 99
>ref|NP_062286.2| roundabout homolog 1 precursor [Mus musculus].
Length = 1612
Score = 157 bits (396), Expect = 4e-38
Identities = 138/473 (29%), Positives = 196/473 (41%), Gaps = 16/473 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKG----DTKLRPTATYKMHFRNN---VATLVFNQVD 170
V+ G+ A+L C+ G P + WYKG +T +++M + +V +
Sbjct: 40 VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 99
Query: 171 SNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
D G YIC A N +GE S +++ L F + DV VG P V EC
Sbjct: 100 RPDEGVYICVARNYLGEAVSHN-ASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGH 158
Query: 351 P-ISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSAR 527
P ++SW KDG PL D T L I T +S AG+Y C TN +G S
Sbjct: 159 PEPTISWKKDGSPLDDKDERITI---RGGKLMITYTRKSDAGKYVCVGTNMVGERESEV- 214
Query: 528 LILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISY 707
LT P F P + + V +SA+F+C G V W KD+ E+ Y+I
Sbjct: 215 AELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRYEI-- 270
Query: 708 LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
+ L I KV GD G YTC A N VGK +A L ++E PP F K + V
Sbjct: 271 -RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQE---PPHFVVKPRDQVVAL- 325
Query: 888 GNSFRLEGRVAGSQPISVAWYKNNVE-----IHPTANCEITFKNNALLLQVKKASMGDAG 1052
G + + G+ ++ W + + P + + L + D G
Sbjct: 326 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVG 385
Query: 1053 LYTCKVSNDAGSALCTSSIVIKE---PKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
Y C+ N AGS + + + + + + PPV Q TV+ L LSC GS
Sbjct: 386 YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLILSCVATGSPAP 445
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
I W K G + D +G VL+ + D G Y C AS +G T
Sbjct: 446 TILWRKDGVLVSTQDSRIKQLESG--VLQIRYAKLGDTGRYTCTASTPSGEAT 496
Score = 129 bits (323), Expect = 1e-29
Identities = 133/522 (25%), Positives = 207/522 (39%), Gaps = 25/522 (4%)
Frame = +3
Query: 246 VQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPL---KDGPNIQTS 416
++++ PP D+ + G P C G ++ W+K G + KD P
Sbjct: 22 LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81
Query: 417 FLDNVATLNIF----QTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPV 584
L + + + + R G Y C A N +G A S + F P + V
Sbjct: 82 LLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRDDFRQNP-SDV 140
Query: 585 DAVVGESADFECHVTGTQPIK-VAWAKDNREIRS--------GGNYQISYLENSAHLTIL 737
VGE A EC P ++W KD + GG I+Y
Sbjct: 141 MVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTR-------- 192
Query: 738 KVDKGDTGQYTCYAVNEVG-KDSCTAQLNIKERLIPPSFTKKLSE-TVEETEGNSFRLEG 911
K D G+Y C N VG ++S A+L + ER PSF K+ S V + F+ E
Sbjct: 193 ---KSDAGKYVCVGTNMVGERESEVAELTVLER---PSFVKRPSNLAVTVDDSAEFKCEA 246
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
R G +V W K++ E+ P + EI + L+++K + GD G YTC N G A
Sbjct: 247 R--GDPVPTVRWRKDDGEL-PKSRYEIRDDHT---LKIRKVTAGDMGSYTCVAENMVGKA 300
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE-----I 1256
++++ ++E PP F V+ G + C G+ I W + G +
Sbjct: 301 EASATLTVQE---PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSY 357
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS--KVTXXXXXXXXXX 1430
+P S + T L +V ++D G Y+C+ NVAGS +K+ +VT
Sbjct: 358 QPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPV 417
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
V+ Q++ V + +A G P P + W K Q RI
Sbjct: 418 IRQGPVN---------QTVAVDGTLILSCVAT--GSPAPTILWRKDGVLVSTQDSRI--- 463
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
++ + L+IR D+G Y C A GE + ++V E
Sbjct: 464 KQLESGVLQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQE 505
Score = 114 bits (286), Expect = 2e-25
Identities = 93/287 (32%), Positives = 132/287 (45%), Gaps = 10/287 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
VTV DSA +C+ G P V W K D +L P + Y++ + TL +V + D G Y
Sbjct: 234 VTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDDH---TLKIRKVTAGDMGSY 289
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C AEN VG+ +S LTVQE PP F + RD +G V F+C +G+ ++ W
Sbjct: 290 TCVAENMVGKAEASATLTVQE---PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR 346
Query: 372 KDGRP----LKDGPNIQTSF-LDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
++G P + F + L I RS G Y C N GS + A L +
Sbjct: 347 REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV 406
Query: 537 TE---GRNPPFFDIPLAPVDAVVGESAD--FECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
T+ R PP I PV+ V C TG+ + W KD + S + +I
Sbjct: 407 TDVIADRPPPV--IRQGPVNQTVAVDGTLILSCVATGSPAPTILWRKDG-VLVSTQDSRI 463
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIP 842
LE S L I GDTG+YTC A G+ + +A + ++E +P
Sbjct: 464 KQLE-SGVLQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVP 509
>ref|NP_001074739.1| Down syndrome cell adhesion molecule-like protein 1 homolog [Mus
musculus].
Length = 2111
Score = 153 bits (386), Expect = 5e-37
Identities = 146/577 (25%), Positives = 226/577 (39%), Gaps = 13/577 (2%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+V G S L C +G P + W K L + + + L + + + DSG
Sbjct: 294 EVWTGHSVELPCAASGYPIPAIRWLKDGRPLPADSRWA----KRITGLTISDLRTEDSGT 349
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
YIC N+ G ++ LTV + P + + ++ +G V+ CA++GS ++ W
Sbjct: 350 YICEVTNTFGSAEANGILTVID---PLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRW 406
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+++ + G I L N TL I +S +G Y C AT +A A ++L +G
Sbjct: 407 YRNTELVLPGEAISIRGLSN-ETLLISSAQKSHSGAYQCFATRKAQTAQDFAIIVLEDG- 464
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS--- 719
P + GE C G P V WA D+ + G+++ + S
Sbjct: 465 -TPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPVVRDGSHRTNQYTMSDGT 523
Query: 720 --AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN 893
+H+ + D G Y C A N VG A++N++ PPS + + G
Sbjct: 524 TISHMNVTGPQIRDGGVYRCTARNSVGSAEYQARINVRG---PPSI--RAMRNITAVAGR 578
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
+ RV G S+ WYK+ + + P + ++ F+N L L + M D G Y C V
Sbjct: 579 DTLINCRVIGYPYYSIKWYKDAL-LLPDNHRQVVFENGTLKLTDVQKGM-DEGEYLCSVL 636
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHV-RGSEPIRIQWLKAGR 1250
L S V K PP+ P S G+ L + C V G PIRI W K G+
Sbjct: 637 --IQPQLSISQSVHVAVKVPPLIQPFEFP-PASIGQLLYIPCVVSSGDMPIRITWRKDGQ 693
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
I + + L+ V+ G+Y C ASN A + + + ++
Sbjct: 694 VIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPR---- 749
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGK-------WRQLNQ 1589
FV +P + + V G P P V W K + +
Sbjct: 750 -----------FVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPL 798
Query: 1590 GGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG 1700
GRI Q + L IR + D G Y C A N G
Sbjct: 799 TGRI---QILPNSSLLIRHVLEEDIGYYLCQASNGVG 832
Score = 135 bits (339), Expect = 2e-31
Identities = 143/611 (23%), Positives = 236/611 (38%), Gaps = 26/611 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+K +G + L C L G+PE + WY+ + P + +N TL+ + + SG
Sbjct: 382 LKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPGEAISIRGLSN-ETLLISSAQKSHSG 440
Query: 186 EYICRAENSVGEVSSSTFLTVQE--QKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C A + +++ ++ SFS ++ + E L CA G+ P +
Sbjct: 441 AYQCFATRKAQTAQDFAIIVLEDGTPRIVSSFSEKVVNPGEQFSL----MCAAKGAPPPT 496
Query: 360 VSWFKDGRP-LKDGPNIQTSFL----DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
V+W D P ++DG + + ++ +N+ G Y CTA N +GSA A
Sbjct: 497 VTWALDDEPVVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNSVGSAEYQA 556
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
R+ + R PP + + AV G C V G + W KD + N++
Sbjct: 557 RINV---RGPPSIR-AMRNITAVAGRDTLINCRVIGYPYYSIKWYKD--ALLLPDNHRQV 610
Query: 705 YLENSAHLTILKVDKG-DTGQYTCYAVNEVGKDSCTAQLNIKERL-----IPPSFTKKLS 866
EN L + V KG D G+Y C + + QL+I + + +PP +
Sbjct: 611 VFENGT-LKLTDVQKGMDEGEYLCSVLIQ-------PQLSISQSVHVAVKVPPLI--QPF 660
Query: 867 ETVEETEGNSFRLEGRV-AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMG 1043
E + G + V +G PI + W K+ I + I K LQ+ S+
Sbjct: 661 EFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLK 720
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
G YTC SN A + ++++ P + V + + G L+C V G P
Sbjct: 721 HNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAG---VLNCSVDGYPPP 777
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLE-----FKDVTKADAGDYVCKASNVAGSDTSK 1388
++ W A P +L + V + D G Y+C+ASN G+D SK
Sbjct: 778 KVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISK 837
Query: 1389 SKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG 1568
+ V S P + ++ G+ ++W KG
Sbjct: 838 A--------------MFLTVKIPAMITSHPNTTIAIKGHPKELNCTARGERPIIIRWEKG 883
Query: 1569 KW-----RQLNQGGRIFIHQKGDE--AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
R + I GDE + L+++ + DS + C A N +GE + L
Sbjct: 884 DTVIDPDRVMRYA--IATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLT 941
Query: 1728 VNERKKQEKIE 1760
V E ++E
Sbjct: 942 VQEPPDPPELE 952
Score = 97.8 bits (242), Expect = 3e-20
Identities = 132/571 (23%), Positives = 213/571 (37%), Gaps = 25/571 (4%)
Frame = +3
Query: 42 CQLAGTPEIGVSWY--KGDTKLRPTATYKMHFRNNVATLVFNQVDSND---SGEYICRAE 206
C AG+P + WY GD +H + F+ N +Y C AE
Sbjct: 105 CPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLFPFSPSAFNSFIHDNDYFCTAE 164
Query: 207 NSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGS--EPIS-VSWFKD 377
N+ G++ S + P ++ ++ D + G VF+C + S E +S VSW KD
Sbjct: 165 NAAGKIRSPNIRIKAVFREP--YTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKD 222
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFA-GQYSCTATNPIGS---ASSSARLILTE- 542
+ F+ + L I + A Y C + S+ ARL +T+
Sbjct: 223 TVSITPENRF---FITSHGGLYISDVQKEDALSTYRCITQHKYSGETRQSNGARLSVTDP 279
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ P + G S + C +G + W KD R + + + +
Sbjct: 280 AESIPTILDGFHSQEVWTGHSVELPCAASGYPIPAIRWLKDGRPLPADSR----WAKRIT 335
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
LTI + D+G Y C N G L + + L KKL + G++
Sbjct: 336 GLTISDLRTEDSGTYICEVTNTFGSAEANGILTVIDPLHVTLTPKKLKTGI----GSTVI 391
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L + GS ++ WY+N + P I +N LL + A +G Y C + A
Sbjct: 392 LSCALTGSPEFTIRWYRNTELVLPGEAISIRGLSNETLL-ISSAQKSHSGAYQCFATRKA 450
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI-- 1256
+A + IV+++ P + V+ GE L C +G+ P + W +
Sbjct: 451 QTAQDFAIIVLED--GTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPVVR 508
Query: 1257 KPSDRCS-FSFANGTAV--LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
S R + ++ ++GT + + D G Y C A N GS ++++
Sbjct: 509 DGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNSVGSAEYQARIN--------- 559
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTA-----TFI-AKVGGDPIPNVKWTKGKWRQLNQ 1589
V P SIR + TA T I +V G P ++KW K L
Sbjct: 560 -------------VRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDA-LLLPD 605
Query: 1590 GGRIFIHQKGDEAKLEIRDTTK-TDSGLYRC 1679
R + + G L++ D K D G Y C
Sbjct: 606 NHRQVVFENG---TLKLTDVQKGMDEGEYLC 633
Score = 84.0 bits (206), Expect = 4e-16
Identities = 103/436 (23%), Positives = 171/436 (39%), Gaps = 21/436 (4%)
Frame = +3
Query: 15 TVGDSASLQCQLA-GTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
++G + C ++ G I ++W K + + + + +++L + V +G Y
Sbjct: 666 SIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNY 725
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A N+ VS L V ++PP F Q + G V C+V G P V W
Sbjct: 726 TCIASNAAATVSRERQLIV---RVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWK 782
Query: 372 K---DGRPLKDGPNIQTSFLDNV--ATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
G P + P T + + ++L I G Y C A+N +G+ S A +
Sbjct: 783 HAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKAMFLT 842
Query: 537 TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGG--NYQISYL 710
+ P A+ G + C G +PI + W K + I Y I+
Sbjct: 843 V--KIPAMITSHPNTTIAIKGHPKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATK 900
Query: 711 ENS----AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE 878
+N + L + D+GD+ ++C+A+N G+D QL ++E PP +
Sbjct: 901 DNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPEL------EIR 954
Query: 879 ETEGNSFRLE--GRVAGSQPIS--VAWYKNNVEI----HPTANCEITFKNNALLLQVKKA 1034
E + S L R G+ I+ YKN + T N T N A ++ + A
Sbjct: 955 EVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTI-NQANIVDLHPA 1013
Query: 1035 SMGDAGLYTC-KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRG 1211
S+ +Y+ K+ S T S P PP+ D L PVT
Sbjct: 1014 SVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPM-DVTLQPVT--------------- 1057
Query: 1212 SEPIRIQWLKAGREIK 1259
S+ I++ W +E++
Sbjct: 1058 SQSIQVTWKAPKKELQ 1073
>ref|NP_112451.1| Down syndrome cell adhesion molecule homolog [Mus musculus].
Length = 2013
Score = 152 bits (384), Expect = 9e-37
Identities = 152/579 (26%), Positives = 232/579 (40%), Gaps = 15/579 (2%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
K G L C+ G PE W K + L + F+ V L+ +DSG
Sbjct: 235 KAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSG----RFQKTVTGLLIENSRPSDSGS 290
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
Y+C N G L V++ P + R V+ +VG V C+V+G+E +SW
Sbjct: 291 YVCEVSNRYGTAKVIGRLYVKQ---PLKATISPRKVKSSVGSQVSLSCSVTGNEDQELSW 347
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+++G L G N++ + L N A L + +S G Y C SA +++L +G
Sbjct: 348 YRNGEILNPGKNVRITGL-NHANLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGT 406
Query: 549 N---PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
F + ++P + V C+V GT V W D+ I G ++IS + S
Sbjct: 407 PKIISAFSEKVVSPAEPV-----SLVCNVKGTPLPTVTWTLDDDPILKGSGHRISQMITS 461
Query: 720 -----AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
++L I D G Y C A N G A++N++ P S + + +
Sbjct: 462 EGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG---PASI--RPMKNITAI 516
Query: 885 EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTC 1064
G + RV G S+ WYK N + P + ++ F+NN L D G YTC
Sbjct: 517 AGRDTYIHCRVIGYPYYSIKWYK-NANLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC 575
Query: 1065 KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSC-HVRGSEPIRIQWLK 1241
V L TS V K PP F Q S G+ + + C V G PI I W K
Sbjct: 576 NVL--VQPQLSTSQSVHVTVKVPP-FIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQK 632
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
GR I S + + T+ L +++ G+Y C A N A + +S++
Sbjct: 633 DGRPIPASLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPK- 691
Query: 1422 XXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW--TKG----KWRQL 1583
FV +P+ + G P+P + W +KG +++ +
Sbjct: 692 --------------FVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPI 737
Query: 1584 NQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG 1700
GRI + G L I+ + DSG Y C N G
Sbjct: 738 ALNGRIQVLSNG---SLLIKHVVEEDSGYYLCKVSNDVG 773
Score = 137 bits (344), Expect = 4e-32
Identities = 147/608 (24%), Positives = 243/608 (39%), Gaps = 23/608 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VK +VG SL C + G + +SWY+ L P ++ N+ A L+ + + +D G
Sbjct: 323 VKSSVGSQVSLSCSVTGNEDQELSWYRNGEILNPGKNVRITGLNH-ANLIMDHMVKSDGG 381
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C ++S+ ++ V + P + + PV C V G+ +V+
Sbjct: 382 AYQCFVRKD--KLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLVCNVKGTPLPTVT 439
Query: 366 WFKDGRPLKDG-----PNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
W D P+ G + TS + V+ LNI + G Y CTA N G AR+
Sbjct: 440 WTLDDDPILKGSGHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARI 499
Query: 531 ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYL 710
+ R P P+ + A+ G C V G + W K N + + Q+++
Sbjct: 500 NV---RGPASIR-PMKNITAIAGRDTYIHCRVIGYPYYSIKWYK-NANLLPFNHRQVAF- 553
Query: 711 ENSAHLTILKVDKG-DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETE 887
EN+ L + V K D G+YTC + + QL+ + + T K+ ++ E
Sbjct: 554 ENNGTLKLSDVQKEVDEGEYTCNVLVQ-------PQLSTSQSV---HVTVKVPPFIQPFE 603
Query: 888 GNSFRLEGR-------VAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGD 1046
F + R V+G PI++ W K+ I + I + L++ S+
Sbjct: 604 FPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPASLGVTIDNIDFTSSLRISNLSLMH 663
Query: 1047 AGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIR 1226
G YTC N+A + S ++++ P K V + + G+ + L+C G
Sbjct: 664 NGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGI---YGKAVILNCSAEGYPVPT 720
Query: 1227 IQW-LKAGREIKPSDRCSFS-----FANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSK 1388
I W G + + + +NG+ ++ K V + D+G Y+CK SN G+D SK
Sbjct: 721 IVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLI--KHVVEEDSGYYLCKVSNDVGADVSK 778
Query: 1389 SKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG 1568
S V S P + + G+ V+W K
Sbjct: 779 S--------------MYLTVKIPAMITSYPNTTLATQGQRKEMSCTAHGEKPIIVRWEKE 824
Query: 1569 KWRQLNQGGRIFIHQK--GDE--AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ R + K G+E + L+I T + DSG + C A N +GE + L V E
Sbjct: 825 DRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQE 884
Query: 1737 RKKQEKIE 1760
+IE
Sbjct: 885 PPDPPEIE 892
Score = 79.0 bits (193), Expect = 1e-14
Identities = 72/297 (24%), Positives = 123/297 (41%), Gaps = 13/297 (4%)
Frame = +3
Query: 9 KVTVGDSASLQCQL-AGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ ++G + C + +G I ++W K + + + + ++L + + +G
Sbjct: 606 RFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPASLGVTIDNIDFTSSLRISNLSLMHNG 665
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C A N V + L V ++PP F Q RD G V+ C+ G ++
Sbjct: 666 NYTCIARNEAAAVEHQSQLIV---RVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIV 722
Query: 366 W-FKDG------RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
W F G +P+ IQ ++ ++ + D +G Y C +N +G A S
Sbjct: 723 WKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEED---SGYYLCKVSNDVG-ADVSK 778
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSG-GNYQI 701
+ LT P + A G+ + C G +PI V W K++R I Y +
Sbjct: 779 SMYLTVKIPAMITSYPNTTL-ATQGQRKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLV 837
Query: 702 SYLENSAH----LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKK 860
S E L IL + D+G ++C+A+N G+D QL ++E PP K
Sbjct: 838 STKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIK 894
>ref|NP_780758.3| roundabout homolog 2 [Mus musculus].
Length = 1508
Score = 151 bits (382), Expect = 2e-36
Identities = 142/517 (27%), Positives = 217/517 (41%), Gaps = 20/517 (3%)
Frame = +3
Query: 246 VQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPL---KDGPNIQTS 416
++++ PP DV + G P C G ++ W+KDG + KD P
Sbjct: 24 LRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRM 83
Query: 417 FL--DNVATLNIFQTDRS--FAGQYSCTATNPIGSA-SSSARLILTEGRNPPFFDIPLAP 581
L ++ L I RS G Y C A N +G A S +A L + R+ D P
Sbjct: 84 LLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRD----DFRQNP 139
Query: 582 VDAVV--GESADFECHVTGTQP-IKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKG 752
D VV GE A EC P + W KD I +IS L I K
Sbjct: 140 TDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRI-DDKEERISI--RGGKLMISNTRKS 196
Query: 753 DTGQYTCYAVNEVG-KDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQ 929
D G YTC N VG +DS A+L + ER P + +++ V E E FR + V G
Sbjct: 197 DAGMYTCVGTNMVGERDSDPAELTVFER--PTFLRRPINQVVLEEEAVEFRCQ--VQGDP 252
Query: 930 PISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSI 1109
+V W K++ ++ P +I + L++KKA D G Y C N G ++++
Sbjct: 253 QPTVRWKKDDADL-PRGRYDI---KDDYTLRIKKAMSTDEGTYVCIAENRVGKVEASATL 308
Query: 1110 VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE--------IKPS 1265
+ + PP F V++G + C +G+ + W K G + +P+
Sbjct: 309 TV---RAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPN 365
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
RCS S T L ++ ++DAG Y+C+A VAGS +K+++
Sbjct: 366 SRCSVS---PTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPP---- 418
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
+ P + + TA K G+P+P + W K + L + R I D+
Sbjct: 419 -----IILQGPINQTLAVDGTALLKCKATGEPLPVISWLKEGFTFLGRDPRATIQ---DQ 470
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
L+I++ +D+G Y CVA + GE + L V E
Sbjct: 471 GTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTE 507
Score = 135 bits (341), Expect = 9e-32
Identities = 125/482 (25%), Positives = 197/482 (40%), Gaps = 18/482 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKG----DTKLRPTATYKMHFRNN---VATLVFNQ 164
V V+ G+ +L C+ G P + WYK +T +++M + +V +
Sbjct: 40 VIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 99
Query: 165 VDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSG 344
D G Y+C A N +GE S +++ L F + DV G P + EC
Sbjct: 100 RSKPDEGSYVCVARNYLGEAVSRN-ASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPR 158
Query: 345 SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
P ++K + D + S L I T +S AG Y+C TN +G S
Sbjct: 159 GHPEPTIYWKKDKVRIDDKEERISI--RGGKLMISNTRKSDAGMYTCVGTNMVGERDSDP 216
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
LT P F P+ V + E+ +F C V G V W KD+ ++ G Y I
Sbjct: 217 -AELTVFERPTFLRRPINQV-VLEEEAVEFRCQVQGDPQPTVRWKKDDADL-PRGRYDI- 272
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
++ L I K D G Y C A N VGK +A L ++ PP F + + +
Sbjct: 273 --KDDYTLRIKKAMSTDEGTYVCIAENRVGKVEASATLTVR---APPQFVVRPRDQI-VA 326
Query: 885 EGNSFRLEGRVAGSQPISVAWYKN--------NVEIHPTANCEITFKNNALLLQVKKASM 1040
+G + G+ +V W K N P + C ++ + + ++++
Sbjct: 327 QGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRS-- 384
Query: 1041 GDAGLYTCKVSNDAGSALCTSSIVIKE---PKKPPVFDQHLTPVTVSEGEFLQLSCHVRG 1211
DAG Y C+ AGS L + + + + + PP+ Q T++ L C G
Sbjct: 385 -DAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATG 443
Query: 1212 SEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS 1391
I WLK G D + GT L+ K++ +D G Y C A++ +G +TS S
Sbjct: 444 EPLPVISWLKEGFTFLGRDPRATIQDQGT--LQIKNLRISDTGTYTCVATSSSG-ETSWS 500
Query: 1392 KV 1397
V
Sbjct: 501 AV 502
Score = 104 bits (260), Expect = 2e-22
Identities = 86/279 (30%), Positives = 124/279 (44%), Gaps = 10/279 (3%)
Frame = +3
Query: 24 DSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRA 203
++ +CQ+ G P+ V W K D L P Y + + TL + S D G Y+C A
Sbjct: 240 EAVEFRCQVQGDPQPTVRWKKDDADL-PRGRYDI---KDDYTLRIKKAMSTDEGTYVCIA 295
Query: 204 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGR 383
EN VG+V +S LTV + PP F + RD G V F C G+ +V W K+G
Sbjct: 296 ENRVGKVEASATLTV---RAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGS 352
Query: 384 P------LKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL----I 533
PN + S + L I RS AG Y C A GS + A+L +
Sbjct: 353 QNLLFPNQPQQPNSRCS-VSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDV 411
Query: 534 LTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
LT+ P P+ AV G +A +C TG ++W K+ G + ++
Sbjct: 412 LTDRPPPIILQGPINQTLAVDG-TALLKCKATGEPLPVISWLKEGFTFL--GRDPRATIQ 468
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKE 830
+ L I + DTG YTC A + G+ S +A L++ E
Sbjct: 469 DQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTE 507
Database: RefSeq49_MP.fasta
Posted date: Oct 17, 2011 1:42 PM
Number of letters in database: 15,617,559
Number of sequences in database: 30,036
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 30036
Number of Hits to DB: 63,287,561
Number of extensions: 1588499
Number of successful extensions: 11301
Number of sequences better than 1.0e-05: 163
Number of HSP's gapped: 7059
Number of HSP's successfully gapped: 891
Length of query: 667
Length of database: 15,617,559
Length adjustment: 108
Effective length of query: 559
Effective length of database: 12,373,671
Effective search space: 6916882089
Effective search space used: 6916882089
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 36 (18.5 bits)
BLASTX 2.2.24 [Aug-08-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MLTL1_0024_C11
(2001 letters)
Database: RefSeq49_SP.fasta
24,897 sequences; 11,343,932 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Alignment gi|XP_003361121.1| PREDICTED: titin-like, partial [Sus scrofa]. 1280 0.0
Alignment gi|XP_003359624.1| PREDICTED: titin-like [Sus scrofa]. 967 0.0
Alignment gi|XP_003359623.1| PREDICTED: titin-like, partial [Sus scrofa]. 224 1e-58
Alignment gi|XP_003123677.2| PREDICTED: LOW QUALITY PROTEIN: obscurin [Su... 155 8e-38
Alignment gi|XP_003130084.1| PREDICTED: roundabout homolog 3 [Sus scrofa]. 155 1e-37
Alignment gi|XP_003129943.2| PREDICTED: Down syndrome cell adhesion molec... 147 2e-35
Alignment gi|XP_003127732.2| PREDICTED: basement membrane-specific hepara... 147 3e-35
Alignment gi|XP_003360572.1| PREDICTED: matrix-remodeling-associated prot... 135 6e-32
Alignment gi|XP_003132540.1| PREDICTED: immunoglobulin superfamily member... 133 3e-31
Alignment gi|XP_003130435.2| PREDICTED: hemicentin-1-like [Sus scrofa]. 129 8e-30
>ref|XP_003361121.1| PREDICTED: titin-like, partial [Sus scrofa].
Length = 7185
Score = 1280 bits (3313), Expect = 0.0
Identities = 640/656 (97%), Positives = 641/656 (97%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS
Sbjct: 5414 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 5473
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV
Sbjct: 5474 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 5533
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE
Sbjct: 5534 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 5593
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA
Sbjct: 5594 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 5653
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR
Sbjct: 5654 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 5713
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA
Sbjct: 5714 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 5773
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP
Sbjct: 5774 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 5833
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT
Sbjct: 5834 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTIKDKPAAIPAAKKA 5893
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD
Sbjct: 5894 AVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 5953
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLK 1802
EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV+ERKKQEKIEGDLRAMLKKTPVLK
Sbjct: 5954 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPVLK 6013
Query: 1803 KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEEETHRL 1970
KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEEETHRL
Sbjct: 6014 KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEEETHRL 6069
Score = 504 bits (1299), Expect = e-143
Identities = 260/578 (44%), Positives = 357/578 (61%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++ +VGDS SLQCQ+AGTPEI VSWYKGDTKLRPT Y+ +F NNVATLVFN+V+ NDS
Sbjct: 3532 PLEASVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDS 3591
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+AENS+G SS T +QE++LPPSF+RQL+DV++TVGLPV C ++GS PI V
Sbjct: 3592 GEYTCKAENSIGTASSKTIFRIQERQLPPSFARQLKDVEQTVGLPVTLTCRLNGSAPIQV 3651
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W++DG L+D N+QTSF+DNVATL I QTD S +GQYSC+A+NP+G+ASSSARL E
Sbjct: 3652 CWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTARE 3711
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ PFFDI +D + GESADFECHVTG QP+++ W+KDN+EIR GGNY I+ + N+
Sbjct: 3712 PKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTP 3771
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
HL ILKV KGD+GQYTC A N+VGKD C+AQL++KE PP F KKL + +G S +
Sbjct: 3772 HLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE---PPKFVKKLEASKVAKQGESIQ 3828
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE +++GS I V W++N+ E+H + ++F N+ LL + +AS D+G Y C+ N
Sbjct: 3829 LECKISGSPEIKVVWFRNDSELHESWKYNMSFVNSVALLTINEASTEDSGDYICEAHNGV 3888
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G A C++++ + K PPVF Q +PV +G + C + G+ P + W+K ++++
Sbjct: 3889 GDASCSTALTV---KAPPVFTQKPSPVGALKGSDVIFQCEISGTPPFEVVWVKDRKQVRS 3945
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + N L ++ +D G+Y CKA+N GSDT V
Sbjct: 3946 SKKFKITSKNFDTSLHILNLEASDIGEYHCKAANEVGSDTCVCTVKFKEPPR-------- 3997
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
FV + + A V G +V W K K + + I +
Sbjct: 3998 -------FVKKLSDTSTLVGDAVELRAVVEGFQPISVVWLKDKGDVIRESENTRISFIDN 4050
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L++ ++SG Y C N G E + L V E
Sbjct: 4051 IATLQLGSPEASNSGKYVCQIKNDAGMRECSAVLTVLE 4088
Score = 493 bits (1268), Expect = e-139
Identities = 254/577 (44%), Positives = 352/577 (61%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ +G+ +LQC++ GTPEI +SWYK TKLR YKM F+NNVA+LV N+VD +D G
Sbjct: 4474 VEAAIGEPVTLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVG 4533
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY C+AENSVG V+SS L ++E+KLPPSF+R+L+DV ET+G PV FEC ++GSEP+ VS
Sbjct: 4534 EYTCKAENSVGAVASSAVLVIKERKLPPSFARKLKDVHETLGFPVAFECRINGSEPLQVS 4593
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+KDG LKD N+QTSF+ NVATL I QTD+S GQY+C+A+NP+G+ASSSA+LIL+E
Sbjct: 4594 WYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLILSEH 4653
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PPFFD+ VD +GES F+CH+TGT PIK+ WAKDNREIR GGNY+++ +EN+A
Sbjct: 4654 EVPPFFDLKPVSVDLALGESGSFKCHITGTAPIKITWAKDNREIRPGGNYKMTLVENTAT 4713
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
LT+LKV KGD GQYTCYA N GKDSC+A L ++E PP F KKL + + R
Sbjct: 4714 LTVLKVGKGDAGQYTCYASNAAGKDSCSAHLGVQE---PPRFIKKLEPSRIVKQDEYTRY 4770
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ GS I V WYK+ EI ++ ++F ++ +L++ S+ D+G YTC+ N AG
Sbjct: 4771 ECKIGGSPEIKVLWYKDETEIQESSKFRMSFLDSVAVLEMHNLSVEDSGDYTCEARNAAG 4830
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
SA ++S+ +KE PPVF + PV +G + L C ++G+ P ++ W K RE++
Sbjct: 4831 SASSSTSLKVKE---PPVFRKKPHPVETLKGADVHLECELQGTPPFQVSWHKDKRELRSG 4887
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ N + +V AD G+Y CKA+N GSDT +T
Sbjct: 4888 KKYKVMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIT--------------- 4932
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
+ FV +P I + A V G +V W K K + + I+I +
Sbjct: 4933 LKASTIFVKKPSDISTIIGEEVQLQATVEGAEPISVVWFKDKGEIVRESDNIWISYSENI 4992
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L+ ++G Y C N G E + + E
Sbjct: 4993 ATLQFSRAEMANAGKYTCQIRNDAGMQECFATVSILE 5029
Score = 336 bits (862), Expect = 2e-92
Identities = 199/580 (34%), Positives = 290/580 (50%), Gaps = 3/580 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++VT GD+ +L+C + GTPE+ W+K +L + YK+ F N V+ L V +DSG
Sbjct: 5040 IRVTTGDTCTLECTVTGTPELTTKWFKDGKELTSDSKYKISFFNKVSGLKIINVAPSDSG 5099
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y +N VG+ S + + V ++ +PPSF+R+L++ G VV EC V GS PISVS
Sbjct: 5100 VYSFEVQNPVGKDSCTASVQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVS 5159
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WF +G + G QT+ DN L + + S AG Y+C ATN GS SA L +
Sbjct: 5160 WFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDAGDYTCIATNVAGSDECSASLTV--- 5216
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
R PP F P+D + G + F V GT P V+W K + E+ G +S ++ A
Sbjct: 5217 REPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAE 5276
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + VD +G+YTC NE GK SCT L +K P F KKL++ E +G S L
Sbjct: 5277 LELFDVDTSQSGEYTCIVSNEAGKVSCTTHLYVK---APAKFVKKLNDYSIE-KGKSLIL 5332
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
EG G+ PISV W KN + I P+ C IT + +L++ +++ DAG Y C + N +G
Sbjct: 5333 EGTYTGTPPISVTWKKNGINISPSQRCNITTTERSAILEIPSSTVEDAGQYNCYIENASG 5392
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
C++ I+I E PP F + L PV V+ G+ L C + G+ I + W K +++P+
Sbjct: 5393 KDSCSAQILILE---PPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPT 5449
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
F N A L F V D+G+Y+C+A N G +S + +T
Sbjct: 5450 ATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLT--------------- 5494
Query: 1446 VDGKLFFVSEPQSIRVVEKTT---ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
V + S + +R V++T F V G +V W K R L G I
Sbjct: 5495 VQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFK-DGRPLKDGPNIQTSFL 5553
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ A L I T ++ +G Y C A N G S+ L + E
Sbjct: 5554 DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 5593
Score = 324 bits (830), Expect = 1e-88
Identities = 190/584 (32%), Positives = 292/584 (50%), Gaps = 3/584 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ VTVG++ +L+C++AGTPE+ V WYK L + +K F N +++L V+ D+
Sbjct: 3157 PMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVERQDA 3216
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y + +N+VG+ S + + V ++ +PPSF+R+L+D +G + EC V+GS PISV
Sbjct: 3217 GTYTFQVQNNVGKSSCTAVVDVSDRMVPPSFTRRLKDTVGVLGTSCILECKVAGSSPISV 3276
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+WF + + G QT+F DNV TL + D S G Y+C A N GS A L + E
Sbjct: 3277 AWFHEKTKIVSGAKYQTAFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSEECRAVLAVQE 3336
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F P++ + G++ F + GT P KV W + +RE+ G I + + A
Sbjct: 3337 ---PPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGSRELVKGDMCNIYFEDTVA 3393
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + V+ ++G+YTC N G+ CT +L +KE P +F KKLS+ E G S
Sbjct: 3394 ELELFNVNISESGEYTCVVSNNAGQTFCTTRLFVKE---PAAFVKKLSDHAVE-PGKSII 3449
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LEG G+ PISV W K+ + I P+ C I +L++ ++ DAG Y+C++ N+A
Sbjct: 3450 LEGTYTGTLPISVTWKKDGLNITPSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEA 3509
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G +C + + E PP F L P+ S G+ + L C V G+ I + W K +++P
Sbjct: 3510 GRDICEALVSTLE---PPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWYKGDTKLRP 3566
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ F N A L F V D+G+Y CKA N G+ +SK+
Sbjct: 3567 TPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKT---------------IF 3611
Query: 1443 XVDGKLFFVSEPQSIRVVEKTT---ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
+ + S + ++ VE+T T ++ G V W + L +
Sbjct: 3612 RIQERQLPPSFARQLKDVEQTVGLPVTLTCRLNGSAPIQVCWYR-DGVLLRDDENLQTSF 3670
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
+ A L+I T + SG Y C A N G S+ L E KK
Sbjct: 3671 VDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKK 3714
Score = 314 bits (804), Expect = 1e-85
Identities = 187/573 (32%), Positives = 282/573 (49%), Gaps = 1/573 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G+S L+C+++G+PEI V W++ D++L + Y M F N+VA L N+ + DSG+YIC
Sbjct: 3824 GESIQLECKISGSPEIKVVWFRNDSELHESWKYNMSFVNSVALLTINEASTEDSGDYICE 3883
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A N VG+ S ST LTV K PP F+++ V G V+F+C +SG+ P V W KD
Sbjct: 3884 AHNGVGDASCSTALTV---KAPPVFTQKPSPVGALKGSDVIFQCEISGTPPFEVVWVKDR 3940
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ ++ + + + +L+I + S G+Y C A N +GS + + E PP
Sbjct: 3941 KQVRSSKKFKITSKNFDTSLHILNLEASDIGEYHCKAANEVGSDTCVCTVKFKE---PPR 3997
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE-IRSGGNYQISYLENSAHLTIL 737
F L+ +VG++ + V G QPI V W KD + IR N +IS+++N A L +
Sbjct: 3998 FVKKLSDTSTLVGDAVELRAVVEGFQPISVVWLKDKGDVIRESENTRISFIDNIATLQLG 4057
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+ ++G+Y C N+ G C+A L + E P+ + E + T GN F LE V
Sbjct: 4058 SPEASNSGKYVCQIKNDAGMRECSAVLTVLE----PARIVEKPEPMTVTTGNPFALECVV 4113
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
AG+ +S W+K+ E+ + ITF N L++ A M D GLY+ +V N G + C
Sbjct: 4114 AGTPELSAKWFKDGRELSADSKHHITFVNKVASLKIPCAEMSDKGLYSFEVKNSVGKSNC 4173
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
T S+ + + PP F + L G + L C V GS PI + W + G E+ +C
Sbjct: 4174 TVSVHVSDRVVPPSFIRKLKDTNAILGGSVVLECRVSGSAPISVGWFQDGNEVVSGPKCQ 4233
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF+ L + +D G Y C A+NVAGSD + +T V
Sbjct: 4234 SSFSENVCTLNLSFLESSDTGTYTCVAANVAGSDECSAILT---------------VQEP 4278
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F P S+ V+ + TF + + G P VKW KG R+L G I + +LE
Sbjct: 4279 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGS-RELVSGESCSISLEDFVTELE 4337
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ + SG Y C+ N G +L V E
Sbjct: 4338 LFEVEPLQSGDYSCLVTNDAGSASCTTHLFVKE 4370
Score = 310 bits (795), Expect = 1e-84
Identities = 195/574 (33%), Positives = 272/574 (47%), Gaps = 1/574 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G S L+ GTP I V+W K + P+ + A L D+G+Y C
Sbjct: 5327 GKSLILEGTYTGTPPISVTWKKNGINISPSQRCNITTTERSAILEIPSSTVEDAGQYNCY 5386
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
EN+ G+ S S + + E PP F +QL V+ TVG +C ++G+ I VSW+K
Sbjct: 5387 IENASGKDSCSAQILILE---PPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGD 5443
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
L+ + F +NVATL Q D + +G+Y C A N +G SSS L + E + PP
Sbjct: 5444 TKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPS 5503
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L V VG FEC V+G++PI V+W KD R ++ G N Q S+L+N A L I +
Sbjct: 5504 FSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQ 5563
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
D+ GQY+C A N +G S +A+L + E PP F L+ V+ G S E V
Sbjct: 5564 TDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLA-PVDAVVGESADFECHVT 5622
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+QPI VAW K+N EI N +I++ N+ L + K GD G YTC N+ G CT
Sbjct: 5623 GTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCT 5682
Query: 1101 SSIVIKEPKKPPVFDQHLT-PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ + IKE PP F + L+ V +EG +L V GS+PI + W K EI P+ C
Sbjct: 5683 AQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCE 5742
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
+F N +L+ K + DAG Y CK SN AGS S +
Sbjct: 5743 ITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP----------- 5791
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F + V E V G ++W K R++ R A LE
Sbjct: 5792 -VFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKA-GREIKPSDRCSFSFANGTAVLE 5849
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
+D TK D+G Y C A N G S + + ++
Sbjct: 5850 FKDVTKADAGDYVCKASNVAGSDTSKSKVTIKDK 5883
Score = 309 bits (792), Expect = 3e-84
Identities = 184/573 (32%), Positives = 283/573 (49%), Gaps = 1/573 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G + +LQ + G+ I V+W KG ++ KM F N VA L+ V + G+Y C
Sbjct: 1413 GQTVTLQAAVRGSEPISVTWMKGQEIIKEDGKIKMSFTNGVAVLIIPDVQISLGGKYTCL 1472
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
AEN G +S L V+E P + +Q T G P E V+G+ + W+KDG
Sbjct: 1473 AENEAGSQTSVGELIVKE---PAKIIERAELIQVTAGDPATLEYTVTGTPELKPKWYKDG 1529
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
RPL + SF +NVA L + + +GQY+ +N +GS+S + + PF
Sbjct: 1530 RPLVASKKYRLSFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPF 1589
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F PL VD++V + +C + G+ P++V+W KD +E+ S Y+I+++E +A L I +
Sbjct: 1590 FTKPLRNVDSIVSGTCRLDCKIAGSLPMRVSWFKDGKEVTSSDRYRIAFVEGTASLEISR 1649
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
VD D G +TC A N VG C+ L ++E PPSF K + + G++ L+
Sbjct: 1650 VDMNDAGNFTCRATNSVGSKDCSGALIVQE---PPSFVIK-PASKDILPGSAVCLKSTFQ 1705
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
GS P+++ W+K N E+ +C IT + L++ D+G YTCKVSN AG+ C+
Sbjct: 1706 GSTPLTIRWFKGNKELVSGGSCYITREALESSLELYSVKTSDSGTYTCKVSNVAGAMECS 1765
Query: 1101 SSIVIKEPKKPPVFDQHLTP-VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ + +KE P F + L P + +G+ QL+C V G+ PI+I W REIK S +
Sbjct: 1766 ADLFVKE---PATFVEKLEPSQLLKKGDATQLACKVAGTPPIKITWFANDREIKESSKHK 1822
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF TAVL DV D+G+Y+C+A N AGSD S V
Sbjct: 1823 MSFVESTAVLRLTDVAVEDSGEYMCEAQNEAGSDHCGS---------------ILIVKES 1867
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
+F E + I V+++ +A+V G P + W K L G + + L+
Sbjct: 1868 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDN-TTLRSGRKYKTFIQDQLVSLQ 1926
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
I D+G Y+C N+ G + + + E
Sbjct: 1927 ILKFVAADAGEYQCRVTNEVGSSTCSARVTLRE 1959
Score = 309 bits (791), Expect = 4e-84
Identities = 192/607 (31%), Positives = 289/607 (47%), Gaps = 1/607 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT D +L+C +AGTPE+ V W K ++ P+ + M F NNVA+ V DSG
Sbjct: 2595 VDVTEKDPVTLECVVAGTPELRVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSG 2654
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY + EN G S +L V +Q +PPSF+++L + + +G + EC VSGS PIS
Sbjct: 2655 EYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQ 2714
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKDG+ + + +N +L++ + Y+C +N G + S L + E
Sbjct: 2715 WFKDGKEITTSAKYRLVCHENTVSLDVNNLELEDTANYTCRVSNVAGDDACSGILTVKE- 2773
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F + A+ + +F+ + GT P KV W KD+ E+ SG I +++
Sbjct: 2774 --PPSFLVKPEWQQAIPDSTVEFKAVLKGTPPFKVKWFKDDVELASGPKCFIGLEGSTSF 2831
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + VD TGQYTC N+VG DSCT L + E PP F KKL + G+S RL
Sbjct: 2832 LNLYSVDASKTGQYTCQVTNDVGSDSCTTMLLVTE---PPKFVKKLEASKIVKAGDSARL 2888
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ GS I V WY+N E+ P+ + F ++ +LQ+ D+G + C+ N AG
Sbjct: 2889 ECKITGSPEIRVVWYRNEHELLPSDKYRMAFIDSVAVLQMNSLGTEDSGDFICEAQNPAG 2948
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
S C++ +++KE PPVF V + + L C + G+ P + W K R+++ S
Sbjct: 2949 STSCSTKVIVKE---PPVFSSFPPVVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSS 3005
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + N A + +V +D G+Y CKA N GSDT V
Sbjct: 3006 KKYKIASKNFHASIHILNVDTSDIGEYHCKAQNEVGSDTCICTVKLKEPPR--------- 3056
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FVS+ S+ VV A A + G +V+W K K + + I I +
Sbjct: 3057 ------FVSKLNSLTVVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRITFVENV 3110
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLK- 1802
A L+ ++G Y C N G E+ L V E + G + + +T L+
Sbjct: 3111 ATLQFAKAEPANAGKYICQIKNDGGMRENMATLTVLEPAVIVEKAGPMTVTVGETCTLEC 3170
Query: 1803 KGAGEEE 1823
K AG E
Sbjct: 3171 KVAGTPE 3177
Score = 305 bits (781), Expect = 6e-83
Identities = 187/582 (32%), Positives = 285/582 (48%), Gaps = 2/582 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ VT G+ +L+C +AGTPE+ W+K +L + + + F N VA+L + +D
Sbjct: 4098 PMTVTTGNPFALECVVAGTPELSAKWFKDGRELSADSKHHITFVNKVASLKIPCAEMSDK 4157
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y +NSVG+ + + + V ++ +PPSF R+L+D +G VV EC VSGS PISV
Sbjct: 4158 GLYSFEVKNSVGKSNCTVSVHVSDRVVPPSFIRKLKDTNAILGGSVVLECRVSGSAPISV 4217
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WF+DG + GP Q+SF +NV TLN+ + S G Y+C A N GS SA L + E
Sbjct: 4218 GWFQDGNEVVSGPKCQSSFSENVCTLNLSFLESSDTGTYTCVAANVAGSDECSAILTVQE 4277
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F+ V+ + G S F + GT P KV W K +RE+ SG + IS +
Sbjct: 4278 ---PPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVSGESCSISLEDFVT 4334
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + +V+ +G Y+C N+ G SCT L +KE P +F K+L++ ET G+
Sbjct: 4335 ELELFEVEPLQSGDYSCLVTNDAGSASCTTHLFVKE---PATFVKRLADFSVET-GSPIV 4390
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE G+ PISV W KN + + NC IT + +L++ +++ D Y+C + N+A
Sbjct: 4391 LEATFTGTPPISVNWMKNEFPLTQSENCSITMTERSSILEILDSTVEDYAQYSCLIENEA 4450
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G +C + + + E PP F + L V + GE + L C V G+ IRI W K +++
Sbjct: 4451 GQDICEALVSVLE---PPYFIEPLEHVEAAIGEPVTLQCKVDGTPEIRISWYKEHTKLRS 4507
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ F N A L V +D G+Y CKA N G+ S + +
Sbjct: 4508 APAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPPS----- 4562
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGG--RIFIHQK 1616
F + + + F ++ G V W K + F+H
Sbjct: 4563 -------FARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVH-- 4613
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
+ A L+I T ++ G Y C A N G S+ L ++E +
Sbjct: 4614 -NVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLILSEHE 4654
Score = 303 bits (775), Expect = 3e-82
Identities = 177/572 (30%), Positives = 287/572 (50%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
GD+ L C++AGTP I ++W+ D +++ ++ +KM F + A L V DSGEY+C
Sbjct: 1789 GDATQLACKVAGTPPIKITWFANDREIKESSKHKMSFVESTAVLRLTDVAVEDSGEYMCE 1848
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A+N G + L V+E P F+++ + ++ V+ V+G+ P ++WFKD
Sbjct: 1849 AQNEAGSDHCGSILIVKES---PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDN 1905
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
L+ G +T D + +L I + + AG+Y C TN +GS++ SAR+ L R PP
Sbjct: 1906 TTLRSGRKYKTFIQDQLVSLQILKFVAADAGEYQCRVTNEVGSSTCSARVTL---REPPA 1962
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F + ++ G +A F+ + G+ PI V W KDN EI N ++++ N A L +
Sbjct: 1963 FVKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENNVASLYLSG 2022
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
++ G+Y C A N+ G C+A L++KE P+ + + +++ T+G+ L+ + +
Sbjct: 2023 IEVKHDGKYVCQAKNDAGIQRCSALLSVKE----PATIIEEAVSIDVTQGDPATLQVKFS 2078
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G++ I+ W+K+ E+ + +I+ + +L++ D+G YT +V ND G + C
Sbjct: 2079 GTKEITARWFKDGQELSLSQKYKISVTDTVSILKIISTEKRDSGEYTFEVQNDVGRSSCK 2138
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSF 1280
++I + + PP F + L + +G F+ L C V GS PI IQW K +EI SD+ F
Sbjct: 2139 ANINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEITASDKYKF 2198
Query: 1281 SFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKL 1460
SF + TA LE + D+G Y C A+N AG + +T V
Sbjct: 2199 SFHDNTAFLEISHLEGTDSGTYTCSATNKAGHNQCSGHLT---------------VKEPP 2243
Query: 1461 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEI 1640
+F+ +PQS V T A VGG +KW K R+L+ G + + LE+
Sbjct: 2244 YFLEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDN-RELHSGAARSVWKDDTSTILEL 2302
Query: 1641 RDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
DSG Y C N G S L V E
Sbjct: 2303 FSAKAADSGTYICQLSNDVGIATSKATLFVKE 2334
Score = 302 bits (773), Expect = 5e-82
Identities = 179/581 (30%), Positives = 283/581 (48%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ V G + + + GTP VSW+KG ++L P + ++VA L VD++ S
Sbjct: 5228 PMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQS 5287
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C N G+VS +T L V K P F ++L D G ++ E +G+ PISV
Sbjct: 5288 GEYTCIVSNEAGKVSCTTHLYV---KAPAKFVKKLNDYSIEKGKSLILEGTYTGTPPISV 5344
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+G + + + A L I + AGQY+C N G S SA++++ E
Sbjct: 5345 TWKKNGINISPSQRCNITTTERSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILE 5404
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP+F L PV VG+SA +C + GT I V+W K + ++R Y++ + N A
Sbjct: 5405 ---PPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVA 5461
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L +VD D+G+Y C A N VG+ S + L ++E+ +PPSF+++L + V+ET G
Sbjct: 5462 TLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRD-VQETVGLPVV 5520
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
E V+GS+PISV+W+K+ + N + +F +N L + + AG Y+C +N
Sbjct: 5521 FECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPI 5580
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GSA ++ +++ E + PP FD L PV GE CHV G++PI++ W K REI+
Sbjct: 5581 GSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRS 5640
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S+ +A L V K D G Y C A N G D+ +++
Sbjct: 5641 GGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPS----- 5695
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
F +++ E + +V G +V W K +++ I K +
Sbjct: 5696 ------FTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNN-VEIHPTANCEITFKNN 5748
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
L+++ + D+GLY C N G ++ + E KK
Sbjct: 5749 ALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKK 5789
Score = 298 bits (764), Expect = 6e-81
Identities = 179/564 (31%), Positives = 272/564 (48%), Gaps = 1/564 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G L+ GTP I V+W K + L + + + L D +Y
Sbjct: 4383 VETGSPIVLEATFTGTPPISVNWMKNEFPLTQSENCSITMTERSSILEILDSTVEDYAQY 4442
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C EN G+ ++V E PP F L V+ +G PV +C V G+ I +SW+
Sbjct: 4443 SCLIENEAGQDICEALVSVLE---PPYFIEPLEHVEAAIGEPVTLQCKVDGTPEIRISWY 4499
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K+ L+ P + F +NVA+L I + D S G+Y+C A N +G+ +SSA L++ E +
Sbjct: 4500 KEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKL 4559
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP F L V +G FEC + G++P++V+W KD ++ N Q S++ N A L
Sbjct: 4560 PPSFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQ 4619
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
IL+ D+ GQY C A N +G S +A+L + E +PP F K +V+ G S +
Sbjct: 4620 ILQTDQSHVGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLK-PVSVDLALGESGSFKC 4678
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
+ G+ PI + W K+N EI P N ++T N L V K GDAG YTC SN AG
Sbjct: 4679 HITGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNAAGKD 4738
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPV-TVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
C++ + ++E PP F + L P V + E+ + C + GS I++ W K EI+ S
Sbjct: 4739 SCSAHLGVQE---PPRFIKKLEPSRIVKQDEYTRYECKIGGSPEIKVLWYKDETEIQESS 4795
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ SF + AVLE +++ D+GDY C+A N AGS +S + + V
Sbjct: 4796 KFRMSFLDSVAVLEMHNLSVEDSGDYTCEARNAAGSASSSTSL---------------KV 4840
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F +P + ++ ++ G P V W K K R+L G + + +
Sbjct: 4841 KEPPVFRKKPHPVETLKGADVHLECELQGTPPFQVSWHKDK-RELRSGKKYKVMSENFLT 4899
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHG 1700
+ I + D G Y+C A N G
Sbjct: 4900 SIHILNVDAADIGEYQCKATNDVG 4923
Score = 295 bits (756), Expect = 5e-80
Identities = 195/606 (32%), Positives = 284/606 (46%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
+G S L+C++AG+ I V+W+ TK+ A Y+ F +NV TL N +DS+D G Y C
Sbjct: 3258 LGTSCILECKVAGSSPISVAWFHEKTKIVSGAKYQTAFSDNVCTLQLNSLDSSDMGNYTC 3317
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKD 377
A N G L VQE PPSF ++ ++ G + F + G+ P V WF+
Sbjct: 3318 VAANVAGSEECRAVLAVQE---PPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRG 3374
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
R L G F D VA L +F + S +G+Y+C +N G + RL + E P
Sbjct: 3375 SRELVKGDMCNIYFEDTVAELELFNVNISESGEYTCVVSNNAGQTFCTTRLFVKE---PA 3431
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F L+ G+S E TGT PI V W KD I I E + L IL
Sbjct: 3432 AFVKKLSDHAVEPGKSIILEGTYTGTLPISVTWKKDGLNITPSEKCNIVTTEKTCILEIL 3491
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
K D GQY+C NE G+D C A ++ E PP F +L E +E + G+S L+ +V
Sbjct: 3492 NSTKRDAGQYSCEIENEAGRDICEALVSTLE---PPYFVTEL-EPLEASVGDSVSLQCQV 3547
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
AG+ I+V+WYK + ++ PT F NN L K ++ D+G YTCK N G+A
Sbjct: 3548 AGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASS 3607
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ I+E + PP F + L V + G + L+C + GS PI++ W + G ++ +
Sbjct: 3608 KTIFRIQERQLPPSFARQLKDVEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQ 3667
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF + A L+ + +G Y C ASN G+ +S +++T
Sbjct: 3668 TSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSP----------- 3716
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
FF +P SI V+ +A F V G + W+K +++ GG I G+ L
Sbjct: 3717 -FFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDN-KEIRPGGNYTITCVGNTPHLR 3774
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAGE 1817
I K DSG Y C A N G+ + L V E K K L+ + V K+G
Sbjct: 3775 ILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVK-------KLEASKVAKQGESI 3827
Query: 1818 EEEIDI 1835
+ E I
Sbjct: 3828 QLECKI 3833
Score = 295 bits (756), Expect = 5e-80
Identities = 172/590 (29%), Positives = 281/590 (47%), Gaps = 1/590 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKL-RPTATYKMHFRNNVATLVFNQVDSNDS 182
+ +G+ LQ + G I V W+K ++ R + + + N+ATL F++ + ++
Sbjct: 4946 ISTIIGEEVQLQATVEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRAEMANA 5005
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y C+ N G +++ E P + + ++ T G EC V+G+ ++
Sbjct: 5006 GKYTCQIRNDAGMQECFATVSILE---PAAIVEKPESIRVTTGDTCTLECTVTGTPELTT 5062
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WFKDG+ L + SF + V+ L I S +G YS NP+G S +A + +++
Sbjct: 5063 KWFKDGKELTSDSKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASVQVSD 5122
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F L + + G S EC V G+ PI V+W + EI SG YQ + +N+
Sbjct: 5123 RTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTC 5182
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
LT+ +++ D G YTC A N G D C+A L ++E PPSF +K + ++ G +
Sbjct: 5183 ALTVNMLEESDAGDYTCIATNVAGSDECSASLTVRE---PPSFVQK-PDPMDVLTGTNVT 5238
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
V G+ P SV+W+K + E+ P C ++ +++ L++ +G YTC VSN+A
Sbjct: 5239 FTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEA 5298
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G CT+ + +K P K F + L ++ +G+ L L G+ PI + W K G I P
Sbjct: 5299 GKVSCTTHLYVKAPAK---FVKKLNDYSIEKGKSLILEGTYTGTPPISVTWKKNGINISP 5355
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S RC+ + +A+LE T DAG Y C N +G D+ +++
Sbjct: 5356 SQRCNITTTERSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPP--------- 5406
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+FV + + ++V +A+ ++ G P V W KG +L +H + +
Sbjct: 5407 ------YFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGD-TKLRPTATYKMHFRNN 5459
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLR 1772
A L DSG Y C A N GE+ S+ L V E+K LR
Sbjct: 5460 VATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR 5509
Score = 295 bits (755), Expect = 6e-80
Identities = 184/579 (31%), Positives = 277/579 (47%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+ G L+C+L GTP VSW+K +LR YK+ N + ++ VD+ D
Sbjct: 4852 PVETLKGADVHLECELQGTPPFQVSWHKDKRELRSGKKYKVMSENFLTSIHILNVDAADI 4911
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+A N VG + +T++ + F ++ D+ +G V + V G+EPISV
Sbjct: 4912 GEYQCKATNDVGSDTCVGSITLKASTI---FVKKPSDISTIIGEEVQLQATVEGAEPISV 4968
Query: 363 SWFKD-GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
WFKD G +++ NI S+ +N+ATL + + + AG+Y+C N G A + +
Sbjct: 4969 VWFKDKGEIVRESDNIWISYSENIATLQFSRAEMANAGKYTCQIRNDAGMQECFATVSIL 5028
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E P + G++ EC VTGT + W KD +E+ S Y+IS+
Sbjct: 5029 E---PAAIVEKPESIRVTTGDTCTLECTVTGTPELTTKWFKDGKELTSDSKYKISFFNKV 5085
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
+ L I+ V D+G Y+ N VGKDSCTA + + +R +PPSFT+KL ET G+S
Sbjct: 5086 SGLKIINVAPSDSGVYSFEVQNPVGKDSCTASVQVSDRTVPPSFTRKLKET-NGLSGSSV 5144
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
+E +V GS PISV+W+ EI + T +N L V DAG YTC +N
Sbjct: 5145 VMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDAGDYTCIATNV 5204
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS C++S+ ++E PP F Q P+ V G + + V+G+ P + W K E+
Sbjct: 5205 AGSDECSASLTVRE---PPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELV 5261
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
P DRC+ S + A LE DV + +G+Y C SN AG + + +
Sbjct: 5262 PGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKVSCTTHL-------------- 5307
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V FV + + + + G P +V W K ++ R I
Sbjct: 5308 -YVKAPAKFVKKLNDYSIEKGKSLILEGTYTGTPPISVTWKK-NGINISPSQRCNITTTE 5365
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A LEI +T D+G Y C N G+ + + + E
Sbjct: 5366 RSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILE 5404
Score = 293 bits (750), Expect = 2e-79
Identities = 181/576 (31%), Positives = 282/576 (48%), Gaps = 1/576 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V GDSA L+C++ G+PEI V WY+ + +L P+ Y+M F ++VA L N + + DSG++
Sbjct: 2880 VKAGDSARLECKITGSPEIRVVWYRNEHELLPSDKYRMAFIDSVAVLQMNSLGTEDSGDF 2939
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
IC A+N G S ST + V+E PP FS V+ V EC +SG+ P V W+
Sbjct: 2940 ICEAQNPAGSTSCSTKVIVKE---PPVFSSFPPVVETLKNAEVSLECELSGTPPFEVVWY 2996
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KD R L+ + + + A+++I D S G+Y C A N +GS + + L E
Sbjct: 2997 KDKRQLRSSKKYKIASKNFHASIHILNVDTSDIGEYHCKAQNEVGSDTCICTVKLKE--- 3053
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE-IRSGGNYQISYLENSAHL 728
PP F L + V GE A+ + + G QPI V W K+ E IR N +I+++EN A L
Sbjct: 3054 PPRFVSKLNSLTVVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRITFVENVATL 3113
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
K + + G+Y C N+ G A L + E P+ + + + T G + LE
Sbjct: 3114 QFAKAEPANAGKYICQIKNDGGMRENMATLTVLE----PAVIVEKAGPMTVTVGETCTLE 3169
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+VAG+ +SV WYK+ + + + +F N L++ DAG YT +V N+ G
Sbjct: 3170 CKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVERQDAGTYTFQVQNNVGK 3229
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
+ CT+ + + + PP F + L G L C V GS PI + W +I
Sbjct: 3230 SSCTAVVDVSDRMVPPSFTRRLKDTVGVLGTSCILECKVAGSSPISVAWFHEKTKIVSGA 3289
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ +F++ L+ + +D G+Y C A+NVAGS+ ++ + V
Sbjct: 3290 KYQTAFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSEECRAVLA---------------V 3334
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
FV EP+ + V+ TF + + G P V W +G R+L +G I+ + A
Sbjct: 3335 QEPPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGS-RELVKGDMCNIYFEDTVA 3393
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+LE+ + ++SG Y CV N G+ L V E
Sbjct: 3394 ELELFNVNISESGEYTCVVSNNAGQTFCTTRLFVKE 3429
Score = 292 bits (747), Expect = 5e-79
Identities = 179/566 (31%), Positives = 269/566 (47%), Gaps = 1/566 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V + SA+ Q +AG+P I ++W K D L + F +NVATL VD+ SG
Sbjct: 2502 VTTVLKSSATFQSTVAGSPPIAITWLKDDQILEEDDNVHISFVDNVATLQIRSVDNGHSG 2561
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C+A+N G FL VQE P + + V T PV EC V+G+ + V
Sbjct: 2562 RYTCQAKNQSGVERCYAFLLVQE---PAQIIEKAKSVDVTEKDPVTLECVVAGTPELRVK 2618
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W KDG+ + SF +NVA+ I + +G+Y+ N GS+S A L + +
Sbjct: 2619 WLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGEYTFKVENDFGSSSCDAYLRVLDQ 2678
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F L +D V+G S EC V+G+ PI W KD +EI + Y++ EN+
Sbjct: 2679 NIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEITTSAKYRLVCHENTVS 2738
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + ++ DT YTC N G D+C+ L +KE PPSF K E + ++
Sbjct: 2739 LDVNNLELEDTANYTCRVSNVAGDDACSGILTVKE---PPSFLVK-PEWQQAIPDSTVEF 2794
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+ + G+ P V W+K++VE+ C I + + L + G YTC+V+ND G
Sbjct: 2795 KAVLKGTPPFKVKWFKDDVELASGPKCFIGLEGSTSFLNLYSVDASKTGQYTCQVTNDVG 2854
Query: 1086 SALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
S CT+ +++ E PP F + L V G+ +L C + GS IR+ W + E+ P
Sbjct: 2855 SDSCTTMLLVTE---PPKFVKKLEASKIVKAGDSARLECKITGSPEIRVVWYRNEHELLP 2911
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
SD+ +F + AVL+ + D+GD++C+A N AGS + +KV
Sbjct: 2912 SDKYRMAFIDSVAVLQMNSLGTEDSGDFICEAQNPAGSTSCSTKV--------------- 2956
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
V F S P + ++ + ++ G P V W K K RQL + I K
Sbjct: 2957 IVKEPPVFSSFPPVVETLKNAEVSLECELSGTPPFEVVWYKDK-RQLRSSKKYKIASKNF 3015
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHG 1700
A + I + +D G Y C A N+ G
Sbjct: 3016 HASIHILNVDTSDIGEYHCKAQNEVG 3041
Score = 288 bits (736), Expect = 1e-77
Identities = 175/564 (31%), Positives = 273/564 (48%), Gaps = 1/564 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G S L+ GT I V+W K + P+ + L D+G+Y
Sbjct: 3442 VEPGKSIILEGTYTGTLPISVTWKKDGLNITPSEKCNIVTTEKTCILEILNSTKRDAGQY 3501
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C EN G ++ E PP F +L ++ +VG V +C V+G+ I+VSW+
Sbjct: 3502 SCEIENEAGRDICEALVSTLE---PPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWY 3558
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K L+ P +T F +NVATL + + + +G+Y+C A N IG+ASS + E +
Sbjct: 3559 KGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTIFRIQERQL 3618
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP F L V+ VG C + G+ PI+V W +D +R N Q S+++N A L
Sbjct: 3619 PPSFARQLKDVEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLK 3678
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
IL+ D +GQY+C A N +G S +A+L +E P F K +++ G S E
Sbjct: 3679 ILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIK-PVSIDVIAGESADFEC 3737
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
V G+QP+ + W K+N EI P N IT N L++ K GD+G YTC+ +ND G
Sbjct: 3738 HVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKD 3797
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVS-EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
+C++ + +KE PP F + L V+ +GE +QL C + GS I++ W + E+ S
Sbjct: 3798 MCSAQLSVKE---PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVVWFRNDSELHESW 3854
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ + SF N A+L + + D+GDY+C+A N G + + +T V
Sbjct: 3855 KYNMSFVNSVALLTINEASTEDSGDYICEAHNGVGDASCSTALT---------------V 3899
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F +P + ++ + F ++ G P V W K + +Q+ + I K +
Sbjct: 3900 KAPPVFTQKPSPVGALKGSDVIFQCEISGTPPFEVVWVKDR-KQVRSSKKFKITSKNFDT 3958
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHG 1700
L I + +D G Y C A N+ G
Sbjct: 3959 SLHILNLEASDIGEYHCKAANEVG 3982
Score = 285 bits (730), Expect = 5e-77
Identities = 174/577 (30%), Positives = 281/577 (48%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++VT GD A+L+ + GTPE+ WYK L + Y++ F+NNVA L F + +DSG
Sbjct: 1501 IQVTAGDPATLEYTVTGTPELKPKWYKDGRPLVASKKYRLSFKNNVAQLKFYSAELHDSG 1560
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y N VG S T TV ++ + P F++ LR+V V +C ++GS P+ VS
Sbjct: 1561 QYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSIVSGTCRLDCKIAGSLPMRVS 1620
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKDG+ + + +F++ A+L I + D + AG ++C ATN +GS S LI+ E
Sbjct: 1621 WFKDGKEVTSSDRYRIAFVEGTASLEISRVDMNDAGNFTCRATNSVGSKDCSGALIVQE- 1679
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F I A D + G + + G+ P+ + W K N+E+ SGG+ I+ +
Sbjct: 1680 --PPSFVIKPASKDILPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITREALESS 1737
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + V D+G YTC N G C+A L +KE P +F +KL + +G++ +L
Sbjct: 1738 LELYSVKTSDSGTYTCKVSNVAGAMECSADLFVKE---PATFVEKLEPSQLLKKGDATQL 1794
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+VAG+ PI + W+ N+ EI ++ +++F + +L++ ++ D+G Y C+ N+AG
Sbjct: 1795 ACKVAGTPPIKITWFANDREIKESSKHKMSFVESTAVLRLTDVAVEDSGEYMCEAQNEAG 1854
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
S C S +++KE P F + P+ V + + L V G+ P I W K ++
Sbjct: 1855 SDHCGSILIVKE---SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSG 1911
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + L+ ADAG+Y C+ +N GS T ++VT
Sbjct: 1912 RKYKTFIQDQLVSLQILKFVAADAGEYQCRVTNEVGSSTCSARVTLREPPA--------- 1962
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FV + +S + TA F A + G V W K ++ + I + + +
Sbjct: 1963 ------FVKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDN-DEITEDDNIRMTFENNV 2015
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L + G Y C A N G + L V E
Sbjct: 2016 ASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE 2052
Score = 282 bits (721), Expect = 6e-76
Identities = 176/578 (30%), Positives = 273/578 (47%), Gaps = 1/578 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTK-LRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
V G+ A LQ + G I V W K + +R + ++ F NVATL F + + ++G+
Sbjct: 3066 VVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGK 3125
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
YIC+ +N G + LTV E P + + TVG EC V+G+ +SV W
Sbjct: 3126 YICQIKNDGGMRENMATLTVLE---PAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEW 3182
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+KDG+ L + SF + +++L I +R AG Y+ N +G +S +A + +++
Sbjct: 3183 YKDGKLLTSSQKHKFSFYNKISSLKILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRM 3242
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP F L V+G S EC V G+ PI VAW + +I SG YQ ++ +N L
Sbjct: 3243 VPPSFTRRLKDTVGVLGTSCILECKVAGSSPISVAWFHEKTKIVSGAKYQTAFSDNVCTL 3302
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
+ +D D G YTC A N G + C A L ++E PPSF K+ E +E G +
Sbjct: 3303 QLNSLDSSDMGNYTCVAANVAGSEECRAVLAVQE---PPSFVKE-PEPLEVLPGKNITFT 3358
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+ G+ P V W++ + E+ C I F++ L++ ++ ++G YTC VSN+AG
Sbjct: 3359 SVIRGTPPFKVGWFRGSRELVKGDMCNIYFEDTVAELELFNVNISESGEYTCVVSNNAGQ 3418
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
CT+ + +KEP F + L+ V G+ + L G+ PI + W K G I PS+
Sbjct: 3419 TFCTTRLFVKEPA---AFVKKLSDHAVEPGKSIILEGTYTGTLPISVTWKKDGLNITPSE 3475
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+C+ T +LE + TK DAG Y C+ N AG D ++ V+
Sbjct: 3476 KCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDICEALVSTLEPP----------- 3524
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
+FV+E + + + + +V G P V W KG +L + + A
Sbjct: 3525 ----YFVTELEPLEASVGDSVSLQCQVAGTPEITVSWYKGD-TKLRPTPEYRTYFTNNVA 3579
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
L DSG Y C A N G S ++ ER+
Sbjct: 3580 TLVFNKVNINDSGEYTCKAENSIGTASSKTIFRIQERQ 3617
Score = 276 bits (707), Expect = 2e-74
Identities = 177/579 (30%), Positives = 271/579 (46%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+ V L+CQ+ ++ V+W K KL P YK++F + +A+L DS
Sbjct: 1127 PVQSAVNKKVHLECQVDEDRKVTVTWSKNGQKLPPGKDYKIYFEDKIASLEIPLAKLKDS 1186
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-GLPVVFECAVSGSEPIS 359
G Y+C A N G SSS +T++E PPSF +++ + G C + GS I
Sbjct: 1187 GTYVCTASNEAGSSSSSATVTIRE---PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQ 1243
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V+WFK+ + L + I+ SF+++ A L+I +G YSC A N +GS S SA +++
Sbjct: 1244 VTWFKNNKELNESNTIRMSFVNSEAVLDITDVKVEDSGSYSCEAVNDVGSDSCSAEIVIK 1303
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E PP F L P D V G +A +C ++GT P +++W KD ++IRS Y++ ++
Sbjct: 1304 E---PPSFIKTLEPADIVRGTNALLQCEISGTGPFEISWFKDKKQIRSSKKYRLFAQKSL 1360
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I + D G+Y C NEVGK C A +KE PP+F KK+ + G +
Sbjct: 1361 VSLEIFSFNSADVGEYECVVANEVGKCGCLATHLLKE---PPTFVKKVDD-FTALAGQTV 1416
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L+ V GS+PISV W K I +++F N +L + + G YTC N+
Sbjct: 1417 TLQAAVRGSEPISVTWMKGQEIIKEDGKIKMSFTNGVAVLIIPDVQISLGGKYTCLAENE 1476
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS +++KEP K + + V+ G+ L V G+ ++ +W K GR +
Sbjct: 1477 AGSQTSVGELIVKEPAK---IIERAELIQVTAGDPATLEYTVTGTPELKPKWYKDGRPLV 1533
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
S + SF N A L+F D+G Y + SN GS + ++ T
Sbjct: 1534 ASKKYRLSFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDR--------- 1584
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
D FF +++ + T K+ G V W K +++ R I
Sbjct: 1585 ---DIAPFFTKPLRNVDSIVSGTCRLDCKIAGSLPMRVSWFK-DGKEVTSSDRYRIAFVE 1640
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A LEI D+G + C A N G + + L V E
Sbjct: 1641 GTASLEISRVDMNDAGNFTCRATNSVGSKDCSGALIVQE 1679
Score = 275 bits (702), Expect = 9e-74
Identities = 171/582 (29%), Positives = 280/582 (48%), Gaps = 4/582 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+V L+C++ GTP V+W K + ++R + Y + + +V L N+ D +D+
Sbjct: 2408 PVEVVKDSDVELECEVMGTPPFEVTWLKNNREIRSSKKYTLTDKVSVFNLNINRCDPSDT 2467
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y C N G S S ++++E PPSF +++ +V + F+ V+GS PI++
Sbjct: 2468 GDYQCIVSNEGGSCSCSARVSLKE---PPSFVKKIENVTTVLKSSATFQSTVAGSPPIAI 2524
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD + L++ N+ SF+DNVATL I D +G+Y+C A N G A L++ E
Sbjct: 2525 TWLKDDQILEEDDNVHISFVDNVATLQIRSVDNGHSGRYTCQAKNQSGVERCYAFLLVQE 2584
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P VD + EC V GT ++V W KD ++I + +S+ N A
Sbjct: 2585 ---PAQIIEKAKSVDVTEKDPVTLECVVAGTPELRVKWLKDGKQIVPSRYFSMSFENNVA 2641
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
I V K D+G+YT N+ G SC A L + ++ IPPSFTKKL++ +++ G+S
Sbjct: 2642 SFRIQSVMKQDSGEYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTK-MDKVLGSSIH 2700
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
+E +V+GS PIS W+K+ EI +A + N + L V + D YTC+VSN A
Sbjct: 2701 MECKVSGSLPISAQWFKDGKEITTSAKYRLVCHENTVSLDVNNLELEDTANYTCRVSNVA 2760
Query: 1083 GSALCTSSIVIKEPKK---PPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
G C+ + +KEP P + Q + TV + ++G+ P +++W K E
Sbjct: 2761 GDDACSGILTVKEPPSFLVKPEWQQAIPDSTV------EFKAVLKGTPPFKVKWFKDDVE 2814
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
+ +C T+ L V + G Y C+ +N GSD+ + +
Sbjct: 2815 LASGPKCFIGLEGSTSFLNLYSVDASKTGQYTCQVTNDVGSDSCTTML------------ 2862
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
V FV + ++ ++V+ +A K+ G P V W + + +L + +
Sbjct: 2863 ---LVTEPPKFVKKLEASKIVKAGDSARLECKITGSPEIRVVWYRNE-HELLPSDKYRMA 2918
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L++ DSG + C A N G + + V E
Sbjct: 2919 FIDSVAVLQMNSLGTEDSGDFICEAQNPAGSTSCSTKVIVKE 2960
Score = 268 bits (686), Expect = 6e-72
Identities = 170/579 (29%), Positives = 274/579 (47%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++V L ++AGTP ++W+K +T LR YK ++ + +L + + D+
Sbjct: 1876 PIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFIQDQLVSLQILKFVAADA 1935
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY CR N VG + S +T++E PP+F +++ G F+ + GS PI+V
Sbjct: 1936 GEYQCRVTNEVGSSTCSARVTLRE---PPAFVKKIESTSSLRGGTAAFQATLKGSLPITV 1992
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD + + NI+ +F +NVA+L + + G+Y C A N G SA L + E
Sbjct: 1993 TWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE 2052
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P +D G+ A + +GT+ I W KD +E+ Y+IS + +
Sbjct: 2053 ---PATIIEEAVSIDVTQGDPATLQVKFSGTKEITARWFKDGQELSLSQKYKISVTDTVS 2109
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I+ +K D+G+YT N+VG+ SC A +N+ + +IPPSFTKKL + ++ +G+
Sbjct: 2110 ILKIISTEKRDSGEYTFEVQNDVGRSSCKANINVLDLIIPPSFTKKLKK-MDSIKGSFID 2168
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE VAGS PIS+ W+K++ EI + + +F +N L++ D+G YTC +N A
Sbjct: 2169 LECIVAGSHPISIQWFKDDQEITASDKYKFSFHDNTAFLEISHLEGTDSGTYTCSATNKA 2228
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G C+ + +KE PP F + V+ +QL V G+ P+ I+W K RE+
Sbjct: 2229 GHNQCSGHLTVKE---PPYFLEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNRELHS 2285
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + +LE AD+G Y+C+ SN G TSK+ +
Sbjct: 2286 GAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGIATSKATL--------------- 2330
Query: 1443 XVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V F+ +P + V+ + TF ++ G P V W +
Sbjct: 2331 FVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPEIRVSWVE------------------ 2372
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+SG Y C A N G ++ L+V E
Sbjct: 2373 -------------NSGTYVCEARNDAGSASCSIELKVKE 2398
Score = 267 bits (682), Expect = 2e-71
Identities = 173/565 (30%), Positives = 257/565 (45%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ VT GD A+LQ + +GT EI W+K +L + YK+ + V+ L + DSG
Sbjct: 2063 IDVTQGDPATLQVKFSGTKEITARWFKDGQELSLSQKYKISVTDTVSILKIISTEKRDSG 2122
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY +N VG S + V + +PPSF+++L+ + G + EC V+GS PIS+
Sbjct: 2123 EYTFEVQNDVGRSSCKANINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQ 2182
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKD + + + SF DN A L I + + +G Y+C+ATN G S L + E
Sbjct: 2183 WFKDDQEITASDKYKFSFHDNTAFLEISHLEGTDSGTYTCSATNKAGHNQCSGHLTVKE- 2241
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP+F D + V GT P+ + W KDNRE+ SG + + S
Sbjct: 2242 --PPYFLEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNRELHSGAARSVWKDDTSTI 2299
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + D+G Y C N+VG + A L +KE PP F KK S + G S
Sbjct: 2300 LELFSAKAADSGTYICQLSNDVGIATSKATLFVKE---PPQFIKKPSPVLVLRNGQSTTF 2356
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ G+ I V+W +N +G Y C+ NDAG
Sbjct: 2357 ECQITGTPEIRVSWVEN------------------------------SGTYVCEARNDAG 2386
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
SA C+ + +KE PP F + L PV V + ++L C V G+ P + WLK REI+ S
Sbjct: 2387 SASCSIELKVKE---PPTFIRELKPVEVVKDSDVELECEVMGTPPFEVTWLKNNREIRSS 2443
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + + L +D GDY C SN GS + ++V+
Sbjct: 2444 KKYTLTDKVSVFNLNINRCDPSDTGDYQCIVSNEGGSCSCSARVSLKEPPS--------- 2494
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FV + +++ V K++ATF + V G P + W K + L + + I +
Sbjct: 2495 ------FVKKIENVTTVLKSSATFQSTVAGSPPIAITWLKDD-QILEEDDNVHISFVDNV 2547
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHG 1700
A L+IR SG Y C A N+ G
Sbjct: 2548 ATLQIRSVDNGHSGRYTCQAKNQSG 2572
Score = 257 bits (656), Expect = 2e-68
Identities = 160/591 (27%), Positives = 279/591 (47%), Gaps = 1/591 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G +A+ Q L G+ I V+W K + ++ +M F NNVA+L + ++ G+Y+C+
Sbjct: 1975 GGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQ 2034
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A+N G S L+V+E P + + + T G P + SG++ I+ WFKDG
Sbjct: 2035 AKNDAGIQRCSALLSVKE---PATIIEEAVSIDVTQGDPATLQVKFSGTKEITARWFKDG 2091
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ L + S D V+ L I T++ +G+Y+ N +G +S A + + + PP
Sbjct: 2092 QELSLSQKYKISVTDTVSILKIISTEKRDSGEYTFEVQNDVGRSSCKANINVLDLIIPPS 2151
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L +D++ G D EC V G+ PI + W KD++EI + Y+ S+ +N+A L I
Sbjct: 2152 FTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEITASDKYKFSFHDNTAFLEISH 2211
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
++ D+G YTC A N+ G + C+ L +KE PP F +K ++ + +L+ V
Sbjct: 2212 LEGTDSGTYTCSATNKAGHNQCSGHLTVKE---PPYFLEK-PQSQDVNPNTRVQLKALVG 2267
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+ P+++ W+K+N E+H A + + + +L++ A D+G Y C++SND G A
Sbjct: 2268 GTAPMTIKWFKDNRELHSGAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGIATSK 2327
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTV-SEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+++ +KEP P F + +PV V G+ C + G+ IR+ W++
Sbjct: 2328 ATLFVKEP---PQFIKKPSPVLVLRNGQSTTFECQITGTPEIRVSWVE------------ 2372
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
++G YVC+A N AGS + ++ V
Sbjct: 2373 ------------------NSGTYVCEARNDAGSASCSIELK---------------VKEP 2399
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F+ E + + VV+ + +V G P V W K R++ + + K L
Sbjct: 2400 PTFIRELKPVEVVKDSDVELECEVMGTPPFEVTWLKNN-REIRSSKKYTLTDKVSVFNLN 2458
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKT 1790
I +D+G Y+C+ N+ G + + + E K ++ +LK +
Sbjct: 2459 INRCDPSDTGDYQCIVSNEGGSCSCSARVSLKEPPSFVKKIENVTTVLKSS 2509
Score = 243 bits (621), Expect = 2e-64
Identities = 168/582 (28%), Positives = 252/582 (43%), Gaps = 1/582 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+V +G A C++ P + W+K ++ + + N V TL + D
Sbjct: 945 PVEVALGHLAKFTCEIHSAPNVRFQWFKAGREIYESDKCSIRSANYVTTLEILRTQVVDC 1004
Query: 183 GEYI-CRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
GEY C +S + + PP+F + + + VG F C V+G+ I
Sbjct: 1005 GEYRKC--------LSYQLDRAIAKMAYPPTFYSRPKSITTFVGKAAKFLCTVTGTPVIE 1056
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
W KDG L PN + S DN L + G YSC A+N G+ A LI+
Sbjct: 1057 TIWQKDGVALSPSPNCKISDADNKHILELSNLTVQDRGVYSCKASNKFGADICQAELIII 1116
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
+ P F L PV + V + EC V + + V W+K+ +++ G +Y+I + +
Sbjct: 1117 D---KPHFIKELEPVQSAVNKKVHLECQVDEDRKVTVTWSKNGQKLPPGKDYKIYFEDKI 1173
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
A L I D+G Y C A NE G S +A + I+E PPSF KK+ + G S
Sbjct: 1174 ASLEIPLAKLKDSGTYVCTASNEAGSSSSSATVTIRE---PPSFVKKVDPSYLMLPGESA 1230
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
RL ++ GS I V W+KNN E++ + ++F N+ +L + + D+G Y+C+ ND
Sbjct: 1231 RLHCKLKGSPVIQVTWFKNNKELNESNTIRMSFVNSEAVLDITDVKVEDSGSYSCEAVND 1290
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
GS C++ IVIKE PP F + L P + G L C + G+ P I W K ++I+
Sbjct: 1291 VGSDSCSAEIVIKE---PPSFIKTLEPADIVRGTNALLQCEISGTGPFEISWFKDKKQIR 1347
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
S + LE AD G+Y C +N G
Sbjct: 1348 SSKKYRLFAQKSLVSLEIFSFNSADVGEYECVVANEVGK---------------CGCLAT 1392
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
+ FV + + T T A V G +V W KG+ + + G+I +
Sbjct: 1393 HLLKEPPTFVKKVDDFTALAGQTVTLQAAVRGSEPISVTWMKGQ-EIIKEDGKIKMSFTN 1451
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
A L I D + G Y C+A N+ G S L V E K
Sbjct: 1452 GVAVLIIPDVQISLGGKYTCLAENEAGSQTSVGELIVKEPAK 1493
Score = 228 bits (582), Expect = 7e-60
Identities = 166/607 (27%), Positives = 269/607 (44%), Gaps = 2/607 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSND-SGEYIC 197
GD+ SL + E V+WY + +K N TLV + V+ + GEY C
Sbjct: 857 GDTISLASSITNAKE--VNWYFEGKLVPSDEKFKCLHDQNTYTLVIDHVNREEHEGEYTC 914
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKD 377
A N G+ ++S LTV + + P R++ V+ +G F C + + + WFK
Sbjct: 915 EASNDSGKAATSAKLTVVK-RAAPVIRRRIEPVEVALGHLAKFTCEIHSAPNVRFQWFKA 973
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
GR + + + V TL I +T G+Y + + R I P
Sbjct: 974 GREIYESDKCSIRSANYVTTLEILRTQVVDCGEYRKCLSYQLD------RAIAKMAYPPT 1027
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F+ P + + VG++A F C VTGT I+ W KD + N +IS +N L +
Sbjct: 1028 FYSRPKS-ITTFVGKAAKFLCTVTGTPVIETIWQKDGVALSPSPNCKISDADNKHILELS 1086
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+ D G Y+C A N+ G D C A+L I ++ P F K+L E V+ LE +V
Sbjct: 1087 NLTVQDRGVYSCKASNKFGADICQAELIIIDK---PHFIKEL-EPVQSAVNKKVHLECQV 1142
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
+ ++V W KN ++ P + +I F++ L++ A + D+G Y C SN+AGS+
Sbjct: 1143 DEDRKVTVTWSKNGQKLPPGKDYKIYFEDKIASLEIPLAKLKDSGTYVCTASNEAGSSSS 1202
Query: 1098 TSSIVIKEPKKPPVFDQHLTP-VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRC 1274
++++ I+E PP F + + P + GE +L C ++GS I++ W K +E+ S+
Sbjct: 1203 SATVTIRE---PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELNESNTI 1259
Query: 1275 SFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDG 1454
SF N AVL+ DV D+G Y C+A N GSD+ +++ +
Sbjct: 1260 RMSFVNSEAVLDITDVKVEDSGSYSCEAVNDVGSDSCSAEIV---------------IKE 1304
Query: 1455 KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKL 1634
F+ + +V T A ++ G + W K K +Q+ + + + L
Sbjct: 1305 PPSFIKTLEPADIVRGTNALLQCEISGTGPFEISWFKDK-KQIRSSKKYRLFAQKSLVSL 1363
Query: 1635 EIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAG 1814
EI D G Y CV N+ G+ + E K D A+ +T L+
Sbjct: 1364 EIFSFNSADVGEYECVVANEVGKCGCLATHLLKEPPTFVKKVDDFTALAGQTVTLQAAVR 1423
Query: 1815 EEEEIDI 1835
E I +
Sbjct: 1424 GSEPISV 1430
Score = 128 bits (322), Expect = 1e-29
Identities = 152/645 (23%), Positives = 262/645 (40%), Gaps = 36/645 (5%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV V+ G+ L C + G+ I + W K +++P+ F N A L F V D+
Sbjct: 5799 PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADA 5858
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLP-PSFSRQLRD-----VQETVGLPVVFECAVS- 341
G+Y+C+A N G +S + +T++++ P+ + D V E + VV + +
Sbjct: 5859 GDYVCKASNVAGSDTSKSKVTIKDKPAAIPAAKKAAVDGKLFFVSEPQSIRVVEKTTATF 5918
Query: 342 ----GSEPI-SVSWFKDG-RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPI 503
G +PI +V W K R L G I + A L I T ++ +G Y C A N
Sbjct: 5919 IAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKH 5978
Query: 504 GSASSSARLILTEGRNPPFFDIPLAPV---DAVVGESADFECHVTGTQPIKVAWAKDNRE 674
G S+ L + E + + L + V+ + A E + + +K K+ +
Sbjct: 5979 GEIESNVNLQVDERKKQEKIEGDLRAMLKKTPVLKKGAGEEEEIDIMELLKNVDPKEYEK 6038
Query: 675 -------------IRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQ 815
+++ + S E + L I +++K + + K+
Sbjct: 6039 YARMYGITDFRGLLQAFEMLKQSQEEETHRLEIEEIEKSEKEE----------KEFEELV 6088
Query: 816 LNIKERLI---PPSFTKKL-SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTAN 983
I++RL P + K + ++TV + + F ++ ++ + I ++WYK ++ P+
Sbjct: 6089 SFIQQRLSQTEPVTLIKDIENQTVLKDDDAVFEIDIKINYPE-IKLSWYKGTEKLEPSDK 6147
Query: 984 CEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPV 1163
EI+ + L+VK + D G Y SA T VI+ P +++HL V
Sbjct: 6148 FEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAKLT---VIE-----PAWERHLQDV 6199
Query: 1164 TVSEGEFLQLSCHVRGSEP-IRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAG 1340
T+ EG+ ++C S P ++ +W + GR +KP R + L DV D G
Sbjct: 6200 TLKEGQTCTMTCQF--SVPNVKSEWFRNGRILKPQGRYKTEVEHKVHKLTIADVRAEDQG 6257
Query: 1341 DYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFI 1520
Y CK ++ S + + + F Q+I V E +ATF
Sbjct: 6258 RYTCKYEDLETSADLRIEAE------------------PIQFTRRIQNIVVSEHQSATFE 6299
Query: 1521 AKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVA-FNKH 1697
+V D V W KG +L + + G + I + T D G+Y +A
Sbjct: 6300 CEVSFDD-AIVTWYKGP-TELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPR 6357
Query: 1698 GEIESNVNLQVNERK-KQEKIEGDLRAMLKKTPVLKKGAGEEEEI 1829
GE S L + ++ K E D+ P + A EEI
Sbjct: 6358 GEARSTAELYLTTKEIKLEMKPPDIPDSRVPIPTMPIRAVPPEEI 6402
Score = 121 bits (304), Expect = 1e-27
Identities = 98/395 (24%), Positives = 167/395 (42%), Gaps = 1/395 (0%)
Frame = +3
Query: 555 PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTI 734
P PLA A G++ +T + +V W + + + S ++ + +N+ L I
Sbjct: 843 PVILTPLADTIAEEGDTISLASSITNAK--EVNWYFEGKLVPSDEKFKCLHDQNTYTLVI 900
Query: 735 LKVDKGD-TGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
V++ + G+YTC A N+ GK + +A+L + +R P ++ E VE G+ +
Sbjct: 901 DHVNREEHEGEYTCEASNDSGKAATSAKLTVVKRAAP--VIRRRIEPVEVALGHLAKFTC 958
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
+ + + W+K EI+ + C I N L++ + + D G Y +S A
Sbjct: 959 EIHSAPNVRFQWFKAGREIYESDKCSIRSANYVTTLEILRTQVVDCGEYRKCLSYQLDRA 1018
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
+ + PP F +T G+ + C V G+ I W K G + PS
Sbjct: 1019 IAKMAY-------PPTFYSRPKSITTFVGKAAKFLCTVTGTPVIETIWQKDGVALSPSPN 1071
Query: 1272 CSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVD 1451
C S A+ +LE ++T D G Y CKASN G+D ++++ +
Sbjct: 1072 CKISDADNKHILELSNLTVQDRGVYSCKASNKFGADICQAEL---------------III 1116
Query: 1452 GKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAK 1631
K F+ E + ++ +V D V W+K ++L G I+ + A
Sbjct: 1117 DKPHFIKELEPVQSAVNKKVHLECQVDEDRKVTVTWSK-NGQKLPPGKDYKIYFEDKIAS 1175
Query: 1632 LEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
LEI DSG Y C A N+ G S+ + + E
Sbjct: 1176 LEIPLAKLKDSGTYVCTASNEAGSSSSSATVTIRE 1210
Score = 89.0 bits (219), Expect = 9e-18
Identities = 59/199 (29%), Positives = 86/199 (43%), Gaps = 23/199 (11%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
++ VGD A L + G P + W+ L P+A YK F N +L+ S D GE
Sbjct: 82 EINVGDVAKLSVTVTGIPRPKIQWFFNGVMLIPSADYKFVFDGNDHSLIILFTKSGDEGE 141
Query: 189 YICRAENSVGEVSSSTFLTVQ--------------------EQKLPPSFSRQLRDVQETV 308
Y C A N G+ + S +L + E PP FS+ L+ V
Sbjct: 142 YTCTASNEHGQATCSAYLKINSKGEEHKEPESAEEKSLEKLEGPCPPYFSKTLKPVHCAQ 201
Query: 309 GLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFL---DNVATLNIFQTDRSFAGQY 479
GLP VFE V G +V WFK+ + L N+ + + D T + + +G Y
Sbjct: 202 GLPAVFEYTVLGEPAPTVLWFKEKKQL--CTNVYYTVIHHPDGSGTFIVNDPQKEDSGLY 259
Query: 480 SCTATNPIGSASSSARLIL 536
C A N G +S+A L++
Sbjct: 260 VCKAENVWGETTSAAELLV 278
Score = 69.7 bits (169), Expect = 6e-12
Identities = 60/220 (27%), Positives = 91/220 (41%), Gaps = 21/220 (9%)
Frame = +3
Query: 222 VSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGP 401
V S F + +E +P F ++ + + VG V+G + WF +G L
Sbjct: 58 VCSVNFSSKKEGSVP-IFIKEASNAEINVGDVAKLSVTVTGIPRPKIQWFFNGVMLIPSA 116
Query: 402 NIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT-------------- 539
+ + F N +L I T G+Y+CTA+N G A+ SA L +
Sbjct: 117 DYKFVFDGNDHSLIILFTKSGDEGEYTCTASNEHGQATCSAYLKINSKGEEHKEPESAEE 176
Query: 540 ------EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQ- 698
EG PP+F L PV G A FE V G V W K+ +++ + Y
Sbjct: 177 KSLEKLEGPCPPYFSKTLKPVHCAQGLPAVFEYTVLGEPAPTVLWFKEKKQLCTNVYYTV 236
Query: 699 ISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQL 818
I + + S + K D+G Y C A N G+ + A+L
Sbjct: 237 IHHPDGSGTFIVNDPQKEDSGLYVCKAENVWGETTSAAEL 276
Score = 68.2 bits (165), Expect = 2e-11
Identities = 58/221 (26%), Positives = 81/221 (36%), Gaps = 8/221 (3%)
Frame = +3
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
+C+ + K+ P+F + + ++ G+ +LS V G +IQW G + PS
Sbjct: 58 VCSVNFSSKKEGSVPIFIKEASNAEINVGDVAKLSVTVTGIPRPKIQWFFNGVMLIPSAD 117
Query: 1272 CSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTS------KSKVTXXXXXXXXXXX 1433
F F L D G+Y C ASN G T SK
Sbjct: 118 YKFVFDGNDHSLIILFTKSGDEGEYTCTASNEHGQATCSAYLKINSKGEEHKEPESAEEK 177
Query: 1434 XXXXVDGKL--FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
++G +F + + + A F V G+P P V W K K + I
Sbjct: 178 SLEKLEGPCPPYFSKTLKPVHCAQGLPAVFEYTVLGEPAPTVLWFKEKKQLCTNVYYTVI 237
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
H + D K DSGLY C A N GE S L V
Sbjct: 238 HHPDGSGTFIVNDPQKEDSGLYVCKAENVWGETTSAAELLV 278
Score = 62.0 bits (149), Expect = 1e-09
Identities = 53/208 (25%), Positives = 80/208 (38%), Gaps = 21/208 (10%)
Frame = +3
Query: 555 PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTI 734
P F + + VG+ A VTG K+ W + + +Y+ + N L I
Sbjct: 72 PIFIKEASNAEINVGDVAKLSVTVTGIPRPKIQWFFNGVMLIPSADYKFVFDGNDHSLII 131
Query: 735 LKVDKGDTGQYTCYAVNEVGKDSCTAQLNIK--------------------ERLIPPSFT 854
L GD G+YTC A NE G+ +C+A L I E PP F+
Sbjct: 132 LFTKSGDEGEYTCTASNEHGQATCSAYLKINSKGEEHKEPESAEEKSLEKLEGPCPPYFS 191
Query: 855 KKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTA-NCEITFKNNALLLQVKK 1031
K L + V +G E V G +V W+K ++ I + + V
Sbjct: 192 KTL-KPVHCAQGLPAVFEYTVLGEPAPTVLWFKEKKQLCTNVYYTVIHHPDGSGTFIVND 250
Query: 1032 ASMGDAGLYTCKVSNDAGSALCTSSIVI 1115
D+GLY CK N G + +++
Sbjct: 251 PQKEDSGLYVCKAENVWGETTSAAELLV 278
>ref|XP_003359624.1| PREDICTED: titin-like [Sus scrofa].
Length = 5926
Score = 967 bits (2500), Expect = 0.0
Identities = 484/499 (96%), Positives = 484/499 (96%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS
Sbjct: 5426 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 5485
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV
Sbjct: 5486 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 5545
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE
Sbjct: 5546 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 5605
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA
Sbjct: 5606 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 5665
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR
Sbjct: 5666 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 5725
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA
Sbjct: 5726 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 5785
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP
Sbjct: 5786 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 5845
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT
Sbjct: 5846 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTIKDKPAAIPAAKKA 5905
Query: 1443 XVDGKLFFVSEPQSIRVVE 1499
VDGKLFFVSEPQSIRVVE
Sbjct: 5906 AVDGKLFFVSEPQSIRVVE 5924
Score = 504 bits (1299), Expect = e-143
Identities = 260/578 (44%), Positives = 357/578 (61%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++ +VGDS SLQCQ+AGTPEI VSWYKGDTKLRPT Y+ +F NNVATLVFN+V+ NDS
Sbjct: 3544 PLEASVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDS 3603
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+AENS+G SS T +QE++LPPSF+RQL+DV++TVGLPV C ++GS PI V
Sbjct: 3604 GEYTCKAENSIGTASSKTIFRIQERQLPPSFARQLKDVEQTVGLPVTLTCRLNGSAPIQV 3663
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W++DG L+D N+QTSF+DNVATL I QTD S +GQYSC+A+NP+G+ASSSARL E
Sbjct: 3664 CWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTARE 3723
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
+ PFFDI +D + GESADFECHVTG QP+++ W+KDN+EIR GGNY I+ + N+
Sbjct: 3724 PKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTP 3783
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
HL ILKV KGD+GQYTC A N+VGKD C+AQL++KE PP F KKL + +G S +
Sbjct: 3784 HLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE---PPKFVKKLEASKVAKQGESIQ 3840
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE +++GS I V W++N+ E+H + ++F N+ LL + +AS D+G Y C+ N
Sbjct: 3841 LECKISGSPEIKVVWFRNDSELHESWKYNMSFVNSVALLTINEASTEDSGDYICEAHNGV 3900
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G A C++++ + K PPVF Q +PV +G + C + G+ P + W+K ++++
Sbjct: 3901 GDASCSTALTV---KAPPVFTQKPSPVGALKGSDVIFQCEISGTPPFEVVWVKDRKQVRS 3957
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + N L ++ +D G+Y CKA+N GSDT V
Sbjct: 3958 SKKFKITSKNFDTSLHILNLEASDIGEYHCKAANEVGSDTCVCTVKFKEPPR-------- 4009
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
FV + + A V G +V W K K + + I +
Sbjct: 4010 -------FVKKLSDTSTLVGDAVELRAVVEGFQPISVVWLKDKGDVIRESENTRISFIDN 4062
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L++ ++SG Y C N G E + L V E
Sbjct: 4063 IATLQLGSPEASNSGKYVCQIKNDAGMRECSAVLTVLE 4100
Score = 491 bits (1265), Expect = e-139
Identities = 254/577 (44%), Positives = 352/577 (61%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ +G+ +LQC++ GTPEI +SWYK TKLR YKM F+NNVA+LV N+VD +D G
Sbjct: 4486 VEAAIGEPVTLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVG 4545
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY C+AENSVG V+SS L ++E+KLPPSF+R+L+DV ET+G PV FEC ++GSEP+ VS
Sbjct: 4546 EYTCKAENSVGAVASSAVLVIKERKLPPSFARKLKDVHETLGFPVAFECRINGSEPLQVS 4605
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W+KDG LKD N+QTSF+ NVATL I QTD+S GQY+C+A+NP+G+ASSSA+LIL+E
Sbjct: 4606 WYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLILSEH 4665
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PPFFD+ VD +GES F+CH+TGT PIK+ WAKDNREIR GGNY+++ +EN+A
Sbjct: 4666 EVPPFFDLKPVSVDLALGESGSFKCHITGTAPIKITWAKDNREIRPGGNYKMTLVENTAT 4725
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
LT+LKV KGD GQYTCYA N GKDSC+A L ++E PP F KKL + + R
Sbjct: 4726 LTVLKVGKGDAGQYTCYASNAAGKDSCSAHLGVQE---PPRFIKKLEPSRIVKQDEYTRY 4782
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ GS I V WYK+ EI ++ ++F ++ +L++ S+ D+G YTC+ N AG
Sbjct: 4783 ECKIGGSPEIKVLWYKDETEIQESSKFRMSFLDSVAVLEMHNLSVEDSGDYTCEARNAAG 4842
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
SA ++S+ +KE PPVF + PV +G + L C ++G+ P ++ W K RE++
Sbjct: 4843 SASSSTSLKVKE---PPVFRKKPHPVETLKGADVHLECELQGTPPFQVSWHKDKRELRSG 4899
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ N + +V AD G+Y CKA+N GSDT +T
Sbjct: 4900 KKYKVMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIT--------------- 4944
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
+ FV +P I + A V G +V W K K + + I+I +
Sbjct: 4945 LKAPPIFVKKPSDISTIIGEEVQLQATVEGAEPISVVWFKDKGEIVRESDNIWISYSENI 5004
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L+ ++G Y C N G E + + E
Sbjct: 5005 ATLQFSRAEMANAGKYTCQIRNDAGMQECFATVSILE 5041
Score = 336 bits (862), Expect = 2e-92
Identities = 199/580 (34%), Positives = 290/580 (50%), Gaps = 3/580 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
++VT GD+ +L+C + GTPE+ W+K +L + YK+ F N V+ L V +DSG
Sbjct: 5052 IRVTTGDTCTLECTVTGTPELTTKWFKDGKELTSDSKYKISFFNKVSGLKIINVAPSDSG 5111
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y +N VG+ S + + V ++ +PPSF+R+L++ G VV EC V GS PISVS
Sbjct: 5112 VYSFEVQNPVGKDSCTASVQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVS 5171
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WF +G + G QT+ DN L + + S AG Y+C ATN GS SA L +
Sbjct: 5172 WFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDAGDYTCIATNVAGSDECSASLTV--- 5228
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
R PP F P+D + G + F V GT P V+W K + E+ G +S ++ A
Sbjct: 5229 REPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAE 5288
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + VD +G+YTC NE GK SCT L +K P F KKL++ E +G S L
Sbjct: 5289 LELFDVDTSQSGEYTCIVSNEAGKVSCTTHLYVK---APAKFVKKLNDYSIE-KGKSLIL 5344
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
EG G+ PISV W KN + I P+ C IT + +L++ +++ DAG Y C + N +G
Sbjct: 5345 EGTYTGTPPISVTWKKNGINISPSQRCNITTTERSAILEIPSSTVEDAGQYNCYIENASG 5404
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
C++ I+I E PP F + L PV V+ G+ L C + G+ I + W K +++P+
Sbjct: 5405 KDSCSAQILILE---PPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPT 5461
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
F N A L F V D+G+Y+C+A N G +S + +T
Sbjct: 5462 ATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLT--------------- 5506
Query: 1446 VDGKLFFVSEPQSIRVVEKTT---ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQK 1616
V + S + +R V++T F V G +V W K R L G I
Sbjct: 5507 VQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFK-DGRPLKDGPNIQTSFL 5565
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ A L I T ++ +G Y C A N G S+ L + E
Sbjct: 5566 DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 5605
Score = 324 bits (830), Expect = 1e-88
Identities = 190/584 (32%), Positives = 292/584 (50%), Gaps = 3/584 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ VTVG++ +L+C++AGTPE+ V WYK L + +K F N +++L V+ D+
Sbjct: 3169 PMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVERQDA 3228
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y + +N+VG+ S + + V ++ +PPSF+R+L+D +G + EC V+GS PISV
Sbjct: 3229 GTYTFQVQNNVGKSSCTAVVDVSDRMVPPSFTRRLKDTVGVLGTSCILECKVAGSSPISV 3288
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+WF + + G QT+F DNV TL + D S G Y+C A N GS A L + E
Sbjct: 3289 AWFHEKTKIVSGAKYQTAFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSEECRAVLAVQE 3348
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F P++ + G++ F + GT P KV W + +RE+ G I + + A
Sbjct: 3349 ---PPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGSRELVKGDMCNIYFEDTVA 3405
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + V+ ++G+YTC N G+ CT +L +KE P +F KKLS+ E G S
Sbjct: 3406 ELELFNVNISESGEYTCVVSNNAGQTFCTTRLFVKE---PAAFVKKLSDHAVE-PGKSII 3461
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LEG G+ PISV W K+ + I P+ C I +L++ ++ DAG Y+C++ N+A
Sbjct: 3462 LEGTYTGTLPISVTWKKDGLNITPSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEA 3521
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G +C + + E PP F L P+ S G+ + L C V G+ I + W K +++P
Sbjct: 3522 GRDICEALVSTLE---PPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWYKGDTKLRP 3578
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ F N A L F V D+G+Y CKA N G+ +SK+
Sbjct: 3579 TPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKT---------------IF 3623
Query: 1443 XVDGKLFFVSEPQSIRVVEKTT---ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQ 1613
+ + S + ++ VE+T T ++ G V W + L +
Sbjct: 3624 RIQERQLPPSFARQLKDVEQTVGLPVTLTCRLNGSAPIQVCWYR-DGVLLRDDENLQTSF 3682
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
+ A L+I T + SG Y C A N G S+ L E KK
Sbjct: 3683 VDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKK 3726
Score = 314 bits (804), Expect = 1e-85
Identities = 187/573 (32%), Positives = 282/573 (49%), Gaps = 1/573 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G+S L+C+++G+PEI V W++ D++L + Y M F N+VA L N+ + DSG+YIC
Sbjct: 3836 GESIQLECKISGSPEIKVVWFRNDSELHESWKYNMSFVNSVALLTINEASTEDSGDYICE 3895
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A N VG+ S ST LTV K PP F+++ V G V+F+C +SG+ P V W KD
Sbjct: 3896 AHNGVGDASCSTALTV---KAPPVFTQKPSPVGALKGSDVIFQCEISGTPPFEVVWVKDR 3952
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ ++ + + + +L+I + S G+Y C A N +GS + + E PP
Sbjct: 3953 KQVRSSKKFKITSKNFDTSLHILNLEASDIGEYHCKAANEVGSDTCVCTVKFKE---PPR 4009
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE-IRSGGNYQISYLENSAHLTIL 737
F L+ +VG++ + V G QPI V W KD + IR N +IS+++N A L +
Sbjct: 4010 FVKKLSDTSTLVGDAVELRAVVEGFQPISVVWLKDKGDVIRESENTRISFIDNIATLQLG 4069
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+ ++G+Y C N+ G C+A L + E P+ + E + T GN F LE V
Sbjct: 4070 SPEASNSGKYVCQIKNDAGMRECSAVLTVLE----PARIVEKPEPMTVTTGNPFALECVV 4125
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
AG+ +S W+K+ E+ + ITF N L++ A M D GLY+ +V N G + C
Sbjct: 4126 AGTPELSAKWFKDGRELSADSKHHITFVNKVASLKIPCAEMSDKGLYSFEVKNSVGKSNC 4185
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
T S+ + + PP F + L G + L C V GS PI + W + G E+ +C
Sbjct: 4186 TVSVHVSDRVVPPSFIRKLKDTNAILGGSVVLECRVSGSAPISVGWFQDGNEVVSGPKCQ 4245
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF+ L + +D G Y C A+NVAGSD + +T V
Sbjct: 4246 SSFSENVCTLNLSFLESSDTGTYTCVAANVAGSDECSAILT---------------VQEP 4290
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F P S+ V+ + TF + + G P VKW KG R+L G I + +LE
Sbjct: 4291 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGS-RELVSGESCSISLEDFVTELE 4349
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+ + SG Y C+ N G +L V E
Sbjct: 4350 LFEVEPLQSGDYSCLVTNDAGSASCTTHLFVKE 4382
Score = 310 bits (795), Expect = 1e-84
Identities = 195/574 (33%), Positives = 272/574 (47%), Gaps = 1/574 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G S L+ GTP I V+W K + P+ + A L D+G+Y C
Sbjct: 5339 GKSLILEGTYTGTPPISVTWKKNGINISPSQRCNITTTERSAILEIPSSTVEDAGQYNCY 5398
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
EN+ G+ S S + + E PP F +QL V+ TVG +C ++G+ I VSW+K
Sbjct: 5399 IENASGKDSCSAQILILE---PPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGD 5455
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
L+ + F +NVATL Q D + +G+Y C A N +G SSS L + E + PP
Sbjct: 5456 TKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPS 5515
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L V VG FEC V+G++PI V+W KD R ++ G N Q S+L+N A L I +
Sbjct: 5516 FSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQ 5575
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
D+ GQY+C A N +G S +A+L + E PP F L+ V+ G S E V
Sbjct: 5576 TDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLA-PVDAVVGESADFECHVT 5634
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+QPI VAW K+N EI N +I++ N+ L + K GD G YTC N+ G CT
Sbjct: 5635 GTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCT 5694
Query: 1101 SSIVIKEPKKPPVFDQHLT-PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ + IKE PP F + L+ V +EG +L V GS+PI + W K EI P+ C
Sbjct: 5695 AQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCE 5754
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
+F N +L+ K + DAG Y CK SN AGS S +
Sbjct: 5755 ITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP----------- 5803
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F + V E V G ++W K R++ R A LE
Sbjct: 5804 -VFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKA-GREIKPSDRCSFSFANGTAVLE 5861
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
+D TK D+G Y C A N G S + + ++
Sbjct: 5862 FKDVTKADAGDYVCKASNVAGSDTSKSKVTIKDK 5895
Score = 309 bits (791), Expect = 4e-84
Identities = 192/607 (31%), Positives = 289/607 (47%), Gaps = 1/607 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT D +L+C +AGTPE+ V W K ++ P+ + M F NNVA+ V DSG
Sbjct: 2607 VDVTEKDPVTLECVVAGTPELRVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSG 2666
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY + EN G S +L V +Q +PPSF+++L + + +G + EC VSGS PIS
Sbjct: 2667 EYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQ 2726
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKDG+ + + +N +L++ + Y+C +N G + S L + E
Sbjct: 2727 WFKDGKEITTSAKYRLVCHENTVSLDVNNLELEDTANYTCRVSNVAGDDACSGILTVKE- 2785
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F + A+ + +F+ + GT P KV W KD+ E+ SG I +++
Sbjct: 2786 --PPSFLVKPEWQQAIPDSTVEFKAVLKGTPPFKVKWFKDDVELASGPKCFIGLEGSTSF 2843
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + VD TGQYTC N+VG DSCT L + E PP F KKL + G+S RL
Sbjct: 2844 LNLYSVDASKTGQYTCQVTNDVGSDSCTTMLLVTE---PPKFVKKLEASKIVKAGDSARL 2900
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ GS I V WY+N E+ P+ + F ++ +LQ+ D+G + C+ N AG
Sbjct: 2901 ECKITGSPEIRVVWYRNEHELLPSDKYRMAFIDSVAVLQMNSLGTEDSGDFICEAQNPAG 2960
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
S C++ +++KE PPVF V + + L C + G+ P + W K R+++ S
Sbjct: 2961 STSCSTKVIVKE---PPVFSSFPPVVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSS 3017
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + N A + +V +D G+Y CKA N GSDT V
Sbjct: 3018 KKYKIASKNFHASIHILNVDTSDIGEYHCKAQNEVGSDTCICTVKLKEPPR--------- 3068
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FVS+ S+ VV A A + G +V+W K K + + I I +
Sbjct: 3069 ------FVSKLNSLTVVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRITFVENV 3122
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLK- 1802
A L+ ++G Y C N G E+ L V E + G + + +T L+
Sbjct: 3123 ATLQFAKAEPANAGKYICQIKNDGGMRENMATLTVLEPAVIVEKAGPMTVTVGETCTLEC 3182
Query: 1803 KGAGEEE 1823
K AG E
Sbjct: 3183 KVAGTPE 3189
Score = 305 bits (781), Expect = 6e-83
Identities = 187/582 (32%), Positives = 285/582 (48%), Gaps = 2/582 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ VT G+ +L+C +AGTPE+ W+K +L + + + F N VA+L + +D
Sbjct: 4110 PMTVTTGNPFALECVVAGTPELSAKWFKDGRELSADSKHHITFVNKVASLKIPCAEMSDK 4169
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G Y +NSVG+ + + + V ++ +PPSF R+L+D +G VV EC VSGS PISV
Sbjct: 4170 GLYSFEVKNSVGKSNCTVSVHVSDRVVPPSFIRKLKDTNAILGGSVVLECRVSGSAPISV 4229
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WF+DG + GP Q+SF +NV TLN+ + S G Y+C A N GS SA L + E
Sbjct: 4230 GWFQDGNEVVSGPKCQSSFSENVCTLNLSFLESSDTGTYTCVAANVAGSDECSAILTVQE 4289
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F+ V+ + G S F + GT P KV W K +RE+ SG + IS +
Sbjct: 4290 ---PPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVSGESCSISLEDFVT 4346
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L + +V+ +G Y+C N+ G SCT L +KE P +F K+L++ ET G+
Sbjct: 4347 ELELFEVEPLQSGDYSCLVTNDAGSASCTTHLFVKE---PATFVKRLADFSVET-GSPIV 4402
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE G+ PISV W KN + + NC IT + +L++ +++ D Y+C + N+A
Sbjct: 4403 LEATFTGTPPISVNWMKNEFPLTQSENCSITMTERSSILEILDSTVEDYAQYSCLIENEA 4462
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G +C + + + E PP F + L V + GE + L C V G+ IRI W K +++
Sbjct: 4463 GQDICEALVSVLE---PPYFIEPLEHVEAAIGEPVTLQCKVDGTPEIRISWYKEHTKLRS 4519
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ F N A L V +D G+Y CKA N G+ S + +
Sbjct: 4520 APAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPPS----- 4574
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGG--RIFIHQK 1616
F + + + F ++ G V W K + F+H
Sbjct: 4575 -------FARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVH-- 4625
Query: 1617 GDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
+ A L+I T ++ G Y C A N G S+ L ++E +
Sbjct: 4626 -NVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLILSEHE 4666
Score = 303 bits (776), Expect = 2e-82
Identities = 187/573 (32%), Positives = 283/573 (49%), Gaps = 1/573 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G + +LQ + G+ I V+W KG ++ KM F N VA L+ V + G+Y C
Sbjct: 1403 GQTVTLQAAVRGSEPISVTWMKGQEIIKEDGKIKMSFTNGVAVLIIPDVQISLGGKYTCL 1462
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
AEN G +S L V+E P + +Q T G P E V+G+ + W+KDG
Sbjct: 1463 AENEAGSQTSVGELIVKE---PAKIIERAELIQVTAGDPATLEYTVTGTPELKPKWYKDG 1519
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
RPL + SF +NVA L + + +GQY+ +N +GS SS R I PF
Sbjct: 1520 RPLVASKKYRLSFKNNVAQLKFYSAELHDSGQYTFEISNEVGS--SSYRDIA------PF 1571
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F PL VD++V + +C + G+ P++V+W KD +E+ S Y+I+++E +A L I +
Sbjct: 1572 FTKPLRNVDSIVSGTCRLDCKIAGSLPMRVSWFKDGKEVTSSDRYRIAFVEGTASLEISR 1631
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
VD D G +TC A N VG C+ L ++E PPSF K + + G++ L+
Sbjct: 1632 VDMNDAGNFTCRATNSVGSKDCSGALIVQE---PPSFVIK-PASKDILPGSAVCLKSTFQ 1687
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
GS P+++ W+K N E+ +C IT + L++ D+G YTCKVSN AG+ C+
Sbjct: 1688 GSTPLTIRWFKGNKELVSGGSCYITREALESSLELYSVKTSDSGTYTCKVSNVAGAMECS 1747
Query: 1101 SSIVIKEPKKPPVFDQHLTP-VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ + +KE P F + L P + +G+ QL+C V G+ PI+I W REIK S +
Sbjct: 1748 ADLFVKE---PATFVEKLEPSQLLKKGDATQLACKVAGTPPIKITWFANDREIKESSKHK 1804
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF TAVL DV D+G+Y+C+A N AGSD S V
Sbjct: 1805 MSFVESTAVLRLTDVAVEDSGEYMCEAQNEAGSDHCGS---------------ILIVKES 1849
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
+F E + I V+++ +A+V G P + W K L G + + L+
Sbjct: 1850 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDN-TTLRSGRKYKTFIQDQLVSLQ 1908
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
I D+G Y+C N+ G + + + E
Sbjct: 1909 ILKFVAADAGEYQCRVTNEVGSSTCSARVTLRE 1941
Score = 303 bits (775), Expect = 3e-82
Identities = 177/572 (30%), Positives = 287/572 (50%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
GD+ L C++AGTP I ++W+ D +++ ++ +KM F + A L V DSGEY+C
Sbjct: 1771 GDATQLACKVAGTPPIKITWFANDREIKESSKHKMSFVESTAVLRLTDVAVEDSGEYMCE 1830
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A+N G + L V+E P F+++ + ++ V+ V+G+ P ++WFKD
Sbjct: 1831 AQNEAGSDHCGSILIVKES---PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDN 1887
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
L+ G +T D + +L I + + AG+Y C TN +GS++ SAR+ L R PP
Sbjct: 1888 TTLRSGRKYKTFIQDQLVSLQILKFVAADAGEYQCRVTNEVGSSTCSARVTL---REPPA 1944
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F + ++ G +A F+ + G+ PI V W KDN EI N ++++ N A L +
Sbjct: 1945 FVKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENNVASLYLSG 2004
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
++ G+Y C A N+ G C+A L++KE P+ + + +++ T+G+ L+ + +
Sbjct: 2005 IEVKHDGKYVCQAKNDAGIQRCSALLSVKE----PATIIEEAVSIDVTQGDPATLQVKFS 2060
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G++ I+ W+K+ E+ + +I+ + +L++ D+G YT +V ND G + C
Sbjct: 2061 GTKEITARWFKDGQELSLSQKYKISVTDTVSILKIISTEKRDSGEYTFEVQNDVGRSSCK 2120
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSF 1280
++I + + PP F + L + +G F+ L C V GS PI IQW K +EI SD+ F
Sbjct: 2121 ANINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEITASDKYKF 2180
Query: 1281 SFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKL 1460
SF + TA LE + D+G Y C A+N AG + +T V
Sbjct: 2181 SFHDNTAFLEISHLEGTDSGTYTCSATNKAGHNQCSGHLT---------------VKEPP 2225
Query: 1461 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEI 1640
+F+ +PQS V T A VGG +KW K R+L+ G + + LE+
Sbjct: 2226 YFLEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDN-RELHSGAARSVWKDDTSTILEL 2284
Query: 1641 RDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
DSG Y C N G S L V E
Sbjct: 2285 FSAKAADSGTYICQLSNDVGIATSKATLFVKE 2316
Score = 302 bits (773), Expect = 5e-82
Identities = 179/581 (30%), Positives = 283/581 (48%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ V G + + + GTP VSW+KG ++L P + ++VA L VD++ S
Sbjct: 5240 PMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQS 5299
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C N G+VS +T L V K P F ++L D G ++ E +G+ PISV
Sbjct: 5300 GEYTCIVSNEAGKVSCTTHLYV---KAPAKFVKKLNDYSIEKGKSLILEGTYTGTPPISV 5356
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W K+G + + + A L I + AGQY+C N G S SA++++ E
Sbjct: 5357 TWKKNGINISPSQRCNITTTERSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILE 5416
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP+F L PV VG+SA +C + GT I V+W K + ++R Y++ + N A
Sbjct: 5417 ---PPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVA 5473
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L +VD D+G+Y C A N VG+ S + L ++E+ +PPSF+++L + V+ET G
Sbjct: 5474 TLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRD-VQETVGLPVV 5532
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
E V+GS+PISV+W+K+ + N + +F +N L + + AG Y+C +N
Sbjct: 5533 FECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPI 5592
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GSA ++ +++ E + PP FD L PV GE CHV G++PI++ W K REI+
Sbjct: 5593 GSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRS 5652
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S+ +A L V K D G Y C A N G D+ +++
Sbjct: 5653 GGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPS----- 5707
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
F +++ E + +V G +V W K +++ I K +
Sbjct: 5708 ------FTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNN-VEIHPTANCEITFKNN 5760
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
L+++ + D+GLY C N G ++ + E KK
Sbjct: 5761 ALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKK 5801
Score = 301 bits (770), Expect = 1e-81
Identities = 187/579 (32%), Positives = 278/579 (48%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+ G L+C+L GTP VSW+K +LR YK+ N + ++ VD+ D
Sbjct: 4864 PVETLKGADVHLECELQGTPPFQVSWHKDKRELRSGKKYKVMSENFLTSIHILNVDAADI 4923
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+A N VG + +T+ K PP F ++ D+ +G V + V G+EPISV
Sbjct: 4924 GEYQCKATNDVGSDTCVGSITL---KAPPIFVKKPSDISTIIGEEVQLQATVEGAEPISV 4980
Query: 363 SWFKD-GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
WFKD G +++ NI S+ +N+ATL + + + AG+Y+C N G A + +
Sbjct: 4981 VWFKDKGEIVRESDNIWISYSENIATLQFSRAEMANAGKYTCQIRNDAGMQECFATVSIL 5040
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E P + G++ EC VTGT + W KD +E+ S Y+IS+
Sbjct: 5041 E---PAAIVEKPESIRVTTGDTCTLECTVTGTPELTTKWFKDGKELTSDSKYKISFFNKV 5097
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
+ L I+ V D+G Y+ N VGKDSCTA + + +R +PPSFT+KL ET G+S
Sbjct: 5098 SGLKIINVAPSDSGVYSFEVQNPVGKDSCTASVQVSDRTVPPSFTRKLKET-NGLSGSSV 5156
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
+E +V GS PISV+W+ EI + T +N L V DAG YTC +N
Sbjct: 5157 VMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDAGDYTCIATNV 5216
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS C++S+ ++E PP F Q P+ V G + + V+G+ P + W K E+
Sbjct: 5217 AGSDECSASLTVRE---PPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELV 5273
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
P DRC+ S + A LE DV + +G+Y C SN AG + + +
Sbjct: 5274 PGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKVSCTTHL-------------- 5319
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
V FV + + + + G P +V W K ++ R I
Sbjct: 5320 -YVKAPAKFVKKLNDYSIEKGKSLILEGTYTGTPPISVTWKK-NGINISPSQRCNITTTE 5377
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A LEI +T D+G Y C N G+ + + + E
Sbjct: 5378 RSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILE 5416
Score = 298 bits (764), Expect = 6e-81
Identities = 179/564 (31%), Positives = 272/564 (48%), Gaps = 1/564 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G L+ GTP I V+W K + L + + + L D +Y
Sbjct: 4395 VETGSPIVLEATFTGTPPISVNWMKNEFPLTQSENCSITMTERSSILEILDSTVEDYAQY 4454
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C EN G+ ++V E PP F L V+ +G PV +C V G+ I +SW+
Sbjct: 4455 SCLIENEAGQDICEALVSVLE---PPYFIEPLEHVEAAIGEPVTLQCKVDGTPEIRISWY 4511
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K+ L+ P + F +NVA+L I + D S G+Y+C A N +G+ +SSA L++ E +
Sbjct: 4512 KEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKL 4571
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP F L V +G FEC + G++P++V+W KD ++ N Q S++ N A L
Sbjct: 4572 PPSFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQ 4631
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
IL+ D+ GQY C A N +G S +A+L + E +PP F K +V+ G S +
Sbjct: 4632 ILQTDQSHVGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLK-PVSVDLALGESGSFKC 4690
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
+ G+ PI + W K+N EI P N ++T N L V K GDAG YTC SN AG
Sbjct: 4691 HITGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNAAGKD 4750
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPV-TVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
C++ + ++E PP F + L P V + E+ + C + GS I++ W K EI+ S
Sbjct: 4751 SCSAHLGVQE---PPRFIKKLEPSRIVKQDEYTRYECKIGGSPEIKVLWYKDETEIQESS 4807
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ SF + AVLE +++ D+GDY C+A N AGS +S + + V
Sbjct: 4808 KFRMSFLDSVAVLEMHNLSVEDSGDYTCEARNAAGSASSSTSL---------------KV 4852
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F +P + ++ ++ G P V W K K R+L G + + +
Sbjct: 4853 KEPPVFRKKPHPVETLKGADVHLECELQGTPPFQVSWHKDK-RELRSGKKYKVMSENFLT 4911
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHG 1700
+ I + D G Y+C A N G
Sbjct: 4912 SIHILNVDAADIGEYQCKATNDVG 4935
Score = 295 bits (756), Expect = 5e-80
Identities = 195/606 (32%), Positives = 284/606 (46%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
+G S L+C++AG+ I V+W+ TK+ A Y+ F +NV TL N +DS+D G Y C
Sbjct: 3270 LGTSCILECKVAGSSPISVAWFHEKTKIVSGAKYQTAFSDNVCTLQLNSLDSSDMGNYTC 3329
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKD 377
A N G L VQE PPSF ++ ++ G + F + G+ P V WF+
Sbjct: 3330 VAANVAGSEECRAVLAVQE---PPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRG 3386
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
R L G F D VA L +F + S +G+Y+C +N G + RL + E P
Sbjct: 3387 SRELVKGDMCNIYFEDTVAELELFNVNISESGEYTCVVSNNAGQTFCTTRLFVKE---PA 3443
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F L+ G+S E TGT PI V W KD I I E + L IL
Sbjct: 3444 AFVKKLSDHAVEPGKSIILEGTYTGTLPISVTWKKDGLNITPSEKCNIVTTEKTCILEIL 3503
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
K D GQY+C NE G+D C A ++ E PP F +L E +E + G+S L+ +V
Sbjct: 3504 NSTKRDAGQYSCEIENEAGRDICEALVSTLE---PPYFVTEL-EPLEASVGDSVSLQCQV 3559
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
AG+ I+V+WYK + ++ PT F NN L K ++ D+G YTCK N G+A
Sbjct: 3560 AGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASS 3619
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+ I+E + PP F + L V + G + L+C + GS PI++ W + G ++ +
Sbjct: 3620 KTIFRIQERQLPPSFARQLKDVEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQ 3679
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF + A L+ + +G Y C ASN G+ +S +++T
Sbjct: 3680 TSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSP----------- 3728
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
FF +P SI V+ +A F V G + W+K +++ GG I G+ L
Sbjct: 3729 -FFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDN-KEIRPGGNYTITCVGNTPHLR 3786
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAGE 1817
I K DSG Y C A N G+ + L V E K K L+ + V K+G
Sbjct: 3787 ILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVK-------KLEASKVAKQGESI 3839
Query: 1818 EEEIDI 1835
+ E I
Sbjct: 3840 QLECKI 3845
Score = 295 bits (756), Expect = 5e-80
Identities = 172/590 (29%), Positives = 281/590 (47%), Gaps = 1/590 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKL-RPTATYKMHFRNNVATLVFNQVDSNDS 182
+ +G+ LQ + G I V W+K ++ R + + + N+ATL F++ + ++
Sbjct: 4958 ISTIIGEEVQLQATVEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRAEMANA 5017
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y C+ N G +++ E P + + ++ T G EC V+G+ ++
Sbjct: 5018 GKYTCQIRNDAGMQECFATVSILE---PAAIVEKPESIRVTTGDTCTLECTVTGTPELTT 5074
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WFKDG+ L + SF + V+ L I S +G YS NP+G S +A + +++
Sbjct: 5075 KWFKDGKELTSDSKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASVQVSD 5134
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
PP F L + + G S EC V G+ PI V+W + EI SG YQ + +N+
Sbjct: 5135 RTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTC 5194
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
LT+ +++ D G YTC A N G D C+A L ++E PPSF +K + ++ G +
Sbjct: 5195 ALTVNMLEESDAGDYTCIATNVAGSDECSASLTVRE---PPSFVQK-PDPMDVLTGTNVT 5250
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
V G+ P SV+W+K + E+ P C ++ +++ L++ +G YTC VSN+A
Sbjct: 5251 FTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEA 5310
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G CT+ + +K P K F + L ++ +G+ L L G+ PI + W K G I P
Sbjct: 5311 GKVSCTTHLYVKAPAK---FVKKLNDYSIEKGKSLILEGTYTGTPPISVTWKKNGINISP 5367
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S RC+ + +A+LE T DAG Y C N +G D+ +++
Sbjct: 5368 SQRCNITTTERSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPP--------- 5418
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+FV + + ++V +A+ ++ G P V W KG +L +H + +
Sbjct: 5419 ------YFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGD-TKLRPTATYKMHFRNN 5471
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLR 1772
A L DSG Y C A N GE+ S+ L V E+K LR
Sbjct: 5472 VATLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR 5521
Score = 293 bits (750), Expect = 2e-79
Identities = 181/576 (31%), Positives = 282/576 (48%), Gaps = 1/576 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V GDSA L+C++ G+PEI V WY+ + +L P+ Y+M F ++VA L N + + DSG++
Sbjct: 2892 VKAGDSARLECKITGSPEIRVVWYRNEHELLPSDKYRMAFIDSVAVLQMNSLGTEDSGDF 2951
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
IC A+N G S ST + V+E PP FS V+ V EC +SG+ P V W+
Sbjct: 2952 ICEAQNPAGSTSCSTKVIVKE---PPVFSSFPPVVETLKNAEVSLECELSGTPPFEVVWY 3008
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KD R L+ + + + A+++I D S G+Y C A N +GS + + L E
Sbjct: 3009 KDKRQLRSSKKYKIASKNFHASIHILNVDTSDIGEYHCKAQNEVGSDTCICTVKLKE--- 3065
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNRE-IRSGGNYQISYLENSAHL 728
PP F L + V GE A+ + + G QPI V W K+ E IR N +I+++EN A L
Sbjct: 3066 PPRFVSKLNSLTVVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRITFVENVATL 3125
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
K + + G+Y C N+ G A L + E P+ + + + T G + LE
Sbjct: 3126 QFAKAEPANAGKYICQIKNDGGMRENMATLTVLE----PAVIVEKAGPMTVTVGETCTLE 3181
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+VAG+ +SV WYK+ + + + +F N L++ DAG YT +V N+ G
Sbjct: 3182 CKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVERQDAGTYTFQVQNNVGK 3241
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
+ CT+ + + + PP F + L G L C V GS PI + W +I
Sbjct: 3242 SSCTAVVDVSDRMVPPSFTRRLKDTVGVLGTSCILECKVAGSSPISVAWFHEKTKIVSGA 3301
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ +F++ L+ + +D G+Y C A+NVAGS+ ++ + V
Sbjct: 3302 KYQTAFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSEECRAVLA---------------V 3346
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
FV EP+ + V+ TF + + G P V W +G R+L +G I+ + A
Sbjct: 3347 QEPPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGS-RELVKGDMCNIYFEDTVA 3405
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
+LE+ + ++SG Y CV N G+ L V E
Sbjct: 3406 ELELFNVNISESGEYTCVVSNNAGQTFCTTRLFVKE 3441
Score = 292 bits (747), Expect = 5e-79
Identities = 179/566 (31%), Positives = 269/566 (47%), Gaps = 1/566 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V + SA+ Q +AG+P I ++W K D L + F +NVATL VD+ SG
Sbjct: 2514 VTTVLKSSATFQSTVAGSPPIAITWLKDDQILEEDDNVHISFVDNVATLQIRSVDNGHSG 2573
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C+A+N G FL VQE P + + V T PV EC V+G+ + V
Sbjct: 2574 RYTCQAKNQSGVERCYAFLLVQE---PAQIIEKAKSVDVTEKDPVTLECVVAGTPELRVK 2630
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W KDG+ + SF +NVA+ I + +G+Y+ N GS+S A L + +
Sbjct: 2631 WLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGEYTFKVENDFGSSSCDAYLRVLDQ 2690
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP F L +D V+G S EC V+G+ PI W KD +EI + Y++ EN+
Sbjct: 2691 NIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEITTSAKYRLVCHENTVS 2750
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + ++ DT YTC N G D+C+ L +KE PPSF K E + ++
Sbjct: 2751 LDVNNLELEDTANYTCRVSNVAGDDACSGILTVKE---PPSFLVK-PEWQQAIPDSTVEF 2806
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
+ + G+ P V W+K++VE+ C I + + L + G YTC+V+ND G
Sbjct: 2807 KAVLKGTPPFKVKWFKDDVELASGPKCFIGLEGSTSFLNLYSVDASKTGQYTCQVTNDVG 2866
Query: 1086 SALCTSSIVIKEPKKPPVFDQHL-TPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
S CT+ +++ E PP F + L V G+ +L C + GS IR+ W + E+ P
Sbjct: 2867 SDSCTTMLLVTE---PPKFVKKLEASKIVKAGDSARLECKITGSPEIRVVWYRNEHELLP 2923
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
SD+ +F + AVL+ + D+GD++C+A N AGS + +KV
Sbjct: 2924 SDKYRMAFIDSVAVLQMNSLGTEDSGDFICEAQNPAGSTSCSTKV--------------- 2968
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
V F S P + ++ + ++ G P V W K K RQL + I K
Sbjct: 2969 IVKEPPVFSSFPPVVETLKNAEVSLECELSGTPPFEVVWYKDK-RQLRSSKKYKIASKNF 3027
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHG 1700
A + I + +D G Y C A N+ G
Sbjct: 3028 HASIHILNVDTSDIGEYHCKAQNEVG 3053
Score = 288 bits (736), Expect = 1e-77
Identities = 175/564 (31%), Positives = 273/564 (48%), Gaps = 1/564 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G S L+ GT I V+W K + P+ + L D+G+Y
Sbjct: 3454 VEPGKSIILEGTYTGTLPISVTWKKDGLNITPSEKCNIVTTEKTCILEILNSTKRDAGQY 3513
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C EN G ++ E PP F +L ++ +VG V +C V+G+ I+VSW+
Sbjct: 3514 SCEIENEAGRDICEALVSTLE---PPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWY 3570
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
K L+ P +T F +NVATL + + + +G+Y+C A N IG+ASS + E +
Sbjct: 3571 KGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTIFRIQERQL 3630
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLT 731
PP F L V+ VG C + G+ PI+V W +D +R N Q S+++N A L
Sbjct: 3631 PPSFARQLKDVEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLK 3690
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEG 911
IL+ D +GQY+C A N +G S +A+L +E P F K +++ G S E
Sbjct: 3691 ILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIK-PVSIDVIAGESADFEC 3749
Query: 912 RVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSA 1091
V G+QP+ + W K+N EI P N IT N L++ K GD+G YTC+ +ND G
Sbjct: 3750 HVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKD 3809
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVS-EGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
+C++ + +KE PP F + L V+ +GE +QL C + GS I++ W + E+ S
Sbjct: 3810 MCSAQLSVKE---PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVVWFRNDSELHESW 3866
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+ + SF N A+L + + D+GDY+C+A N G + + +T V
Sbjct: 3867 KYNMSFVNSVALLTINEASTEDSGDYICEAHNGVGDASCSTALT---------------V 3911
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
F +P + ++ + F ++ G P V W K + +Q+ + I K +
Sbjct: 3912 KAPPVFTQKPSPVGALKGSDVIFQCEISGTPPFEVVWVKDR-KQVRSSKKFKITSKNFDT 3970
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHG 1700
L I + +D G Y C A N+ G
Sbjct: 3971 SLHILNLEASDIGEYHCKAANEVG 3994
Score = 287 bits (734), Expect = 2e-77
Identities = 179/565 (31%), Positives = 268/565 (47%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+ VT GD A+LQ + +GT EI W+K +L + YK+ + V+ L + DSG
Sbjct: 2045 IDVTQGDPATLQVKFSGTKEITARWFKDGQELSLSQKYKISVTDTVSILKIISTEKRDSG 2104
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
EY +N VG S + V + +PPSF+++L+ + G + EC V+GS PIS+
Sbjct: 2105 EYTFEVQNDVGRSSCKANINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQ 2164
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
WFKD + + + SF DN A L I + + +G Y+C+ATN G S L + E
Sbjct: 2165 WFKDDQEITASDKYKFSFHDNTAFLEISHLEGTDSGTYTCSATNKAGHNQCSGHLTVKE- 2223
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
PP+F D + V GT P+ + W KDNRE+ SG + + S
Sbjct: 2224 --PPYFLEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNRELHSGAARSVWKDDTSTI 2281
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L + D+G Y C N+VG + A L +KE PP F KK S + G S
Sbjct: 2282 LELFSAKAADSGTYICQLSNDVGIATSKATLFVKE---PPQFIKKPSPVLVLRNGQSTTF 2338
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
E ++ G+ I V+WY + EI I+F + Q+ A + ++G Y C+ NDAG
Sbjct: 2339 ECQITGTPEIRVSWYLDGNEITAIERHGISFIDGLATFQISGARVENSGTYVCEARNDAG 2398
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
SA C+ + +KE PP F + L PV V + ++L C V G+ P + WLK REI+ S
Sbjct: 2399 SASCSIELKVKE---PPTFIRELKPVEVVKDSDVELECEVMGTPPFEVTWLKNNREIRSS 2455
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
+ + + L +D GDY C SN GS + ++V+
Sbjct: 2456 KKYTLTDKVSVFNLNINRCDPSDTGDYQCIVSNEGGSCSCSARVSLKEPPS--------- 2506
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
FV + +++ V K++ATF + V G P + W K + L + + I +
Sbjct: 2507 ------FVKKIENVTTVLKSSATFQSTVAGSPPIAITWLKDD-QILEEDDNVHISFVDNV 2559
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHG 1700
A L+IR SG Y C A N+ G
Sbjct: 2560 ATLQIRSVDNGHSGRYTCQAKNQSG 2584
Score = 282 bits (721), Expect = 6e-76
Identities = 168/591 (28%), Positives = 288/591 (48%), Gaps = 1/591 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G +A+ Q L G+ I V+W K + ++ +M F NNVA+L + ++ G+Y+C+
Sbjct: 1957 GGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQ 2016
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
A+N G S L+V+E P + + + T G P + SG++ I+ WFKDG
Sbjct: 2017 AKNDAGIQRCSALLSVKE---PATIIEEAVSIDVTQGDPATLQVKFSGTKEITARWFKDG 2073
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
+ L + S D V+ L I T++ +G+Y+ N +G +S A + + + PP
Sbjct: 2074 QELSLSQKYKISVTDTVSILKIISTEKRDSGEYTFEVQNDVGRSSCKANINVLDLIIPPS 2133
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L +D++ G D EC V G+ PI + W KD++EI + Y+ S+ +N+A L I
Sbjct: 2134 FTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEITASDKYKFSFHDNTAFLEISH 2193
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
++ D+G YTC A N+ G + C+ L +KE PP F +K ++ + +L+ V
Sbjct: 2194 LEGTDSGTYTCSATNKAGHNQCSGHLTVKE---PPYFLEK-PQSQDVNPNTRVQLKALVG 2249
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
G+ P+++ W+K+N E+H A + + + +L++ A D+G Y C++SND G A
Sbjct: 2250 GTAPMTIKWFKDNRELHSGAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGIATSK 2309
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTV-SEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCS 1277
+++ +KE PP F + +PV V G+ C + G+ IR+ W G EI +R
Sbjct: 2310 ATLFVKE---PPQFIKKPSPVLVLRNGQSTTFECQITGTPEIRVSWYLDGNEITAIERHG 2366
Query: 1278 FSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK 1457
SF +G A + ++G YVC+A N AGS + ++ V
Sbjct: 2367 ISFIDGLATFQISGARVENSGTYVCEARNDAGSASCSIEL---------------KVKEP 2411
Query: 1458 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLE 1637
F+ E + + VV+ + +V G P V W K R++ + + K L
Sbjct: 2412 PTFIRELKPVEVVKDSDVELECEVMGTPPFEVTWLKNN-REIRSSKKYTLTDKVSVFNLN 2470
Query: 1638 IRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKT 1790
I +D+G Y+C+ N+ G + + + E K ++ +LK +
Sbjct: 2471 INRCDPSDTGDYQCIVSNEGGSCSCSARVSLKEPPSFVKKIENVTTVLKSS 2521
Score = 282 bits (721), Expect = 6e-76
Identities = 176/578 (30%), Positives = 273/578 (47%), Gaps = 1/578 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTK-LRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
V G+ A LQ + G I V W K + +R + ++ F NVATL F + + ++G+
Sbjct: 3078 VVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGK 3137
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
YIC+ +N G + LTV E P + + TVG EC V+G+ +SV W
Sbjct: 3138 YICQIKNDGGMRENMATLTVLE---PAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEW 3194
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+KDG+ L + SF + +++L I +R AG Y+ N +G +S +A + +++
Sbjct: 3195 YKDGKLLTSSQKHKFSFYNKISSLKILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRM 3254
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHL 728
PP F L V+G S EC V G+ PI VAW + +I SG YQ ++ +N L
Sbjct: 3255 VPPSFTRRLKDTVGVLGTSCILECKVAGSSPISVAWFHEKTKIVSGAKYQTAFSDNVCTL 3314
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
+ +D D G YTC A N G + C A L ++E PPSF K+ E +E G +
Sbjct: 3315 QLNSLDSSDMGNYTCVAANVAGSEECRAVLAVQE---PPSFVKE-PEPLEVLPGKNITFT 3370
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGS 1088
+ G+ P V W++ + E+ C I F++ L++ ++ ++G YTC VSN+AG
Sbjct: 3371 SVIRGTPPFKVGWFRGSRELVKGDMCNIYFEDTVAELELFNVNISESGEYTCVVSNNAGQ 3430
Query: 1089 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSD 1268
CT+ + +KEP F + L+ V G+ + L G+ PI + W K G I PS+
Sbjct: 3431 TFCTTRLFVKEPA---AFVKKLSDHAVEPGKSIILEGTYTGTLPISVTWKKDGLNITPSE 3487
Query: 1269 RCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXV 1448
+C+ T +LE + TK DAG Y C+ N AG D ++ V+
Sbjct: 3488 KCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDICEALVSTLEPP----------- 3536
Query: 1449 DGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEA 1628
+FV+E + + + + +V G P V W KG +L + + A
Sbjct: 3537 ----YFVTELEPLEASVGDSVSLQCQVAGTPEITVSWYKGD-TKLRPTPEYRTYFTNNVA 3591
Query: 1629 KLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
L DSG Y C A N G S ++ ER+
Sbjct: 3592 TLVFNKVNINDSGEYTCKAENSIGTASSKTIFRIQERQ 3629
Score = 275 bits (703), Expect = 7e-74
Identities = 175/581 (30%), Positives = 282/581 (48%), Gaps = 3/581 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P++V L ++AGTP ++W+K +T LR YK ++ + +L + + D+
Sbjct: 1858 PIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFIQDQLVSLQILKFVAADA 1917
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY CR N VG + S +T++E PP+F +++ G F+ + GS PI+V
Sbjct: 1918 GEYQCRVTNEVGSSTCSARVTLRE---PPAFVKKIESTSSLRGGTAAFQATLKGSLPITV 1974
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD + + NI+ +F +NVA+L + + G+Y C A N G SA L + E
Sbjct: 1975 TWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE 2034
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P +D G+ A + +GT+ I W KD +E+ Y+IS + +
Sbjct: 2035 ---PATIIEEAVSIDVTQGDPATLQVKFSGTKEITARWFKDGQELSLSQKYKISVTDTVS 2091
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I+ +K D+G+YT N+VG+ SC A +N+ + +IPPSFTKKL + ++ +G+
Sbjct: 2092 ILKIISTEKRDSGEYTFEVQNDVGRSSCKANINVLDLIIPPSFTKKLKK-MDSIKGSFID 2150
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE VAGS PIS+ W+K++ EI + + +F +N L++ D+G YTC +N A
Sbjct: 2151 LECIVAGSHPISIQWFKDDQEITASDKYKFSFHDNTAFLEISHLEGTDSGTYTCSATNKA 2210
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G C+ + +KE PP F + V+ +QL V G+ P+ I+W K RE+
Sbjct: 2211 GHNQCSGHLTVKE---PPYFLEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNRELHS 2267
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + + +LE AD+G Y+C+ SN G TSK+ +
Sbjct: 2268 GAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGIATSKATL--------------- 2312
Query: 1443 XVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDPIPNVKW--TKGKWRQLNQGGRIFIHQ 1613
V F+ +P + V+ + TF ++ G P V W + + + G FI
Sbjct: 2313 FVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPEIRVSWYLDGNEITAIERHGISFI-- 2370
Query: 1614 KGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A +I +SG Y C A N G ++ L+V E
Sbjct: 2371 -DGLATFQISGARVENSGTYVCEARNDAGSASCSIELKVKE 2410
Score = 275 bits (702), Expect = 9e-74
Identities = 171/582 (29%), Positives = 280/582 (48%), Gaps = 4/582 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+V L+C++ GTP V+W K + ++R + Y + + +V L N+ D +D+
Sbjct: 2420 PVEVVKDSDVELECEVMGTPPFEVTWLKNNREIRSSKKYTLTDKVSVFNLNINRCDPSDT 2479
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
G+Y C N G S S ++++E PPSF +++ +V + F+ V+GS PI++
Sbjct: 2480 GDYQCIVSNEGGSCSCSARVSLKE---PPSFVKKIENVTTVLKSSATFQSTVAGSPPIAI 2536
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W KD + L++ N+ SF+DNVATL I D +G+Y+C A N G A L++ E
Sbjct: 2537 TWLKDDQILEEDDNVHISFVDNVATLQIRSVDNGHSGRYTCQAKNQSGVERCYAFLLVQE 2596
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P VD + EC V GT ++V W KD ++I + +S+ N A
Sbjct: 2597 ---PAQIIEKAKSVDVTEKDPVTLECVVAGTPELRVKWLKDGKQIVPSRYFSMSFENNVA 2653
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
I V K D+G+YT N+ G SC A L + ++ IPPSFTKKL++ +++ G+S
Sbjct: 2654 SFRIQSVMKQDSGEYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTK-MDKVLGSSIH 2712
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
+E +V+GS PIS W+K+ EI +A + N + L V + D YTC+VSN A
Sbjct: 2713 MECKVSGSLPISAQWFKDGKEITTSAKYRLVCHENTVSLDVNNLELEDTANYTCRVSNVA 2772
Query: 1083 GSALCTSSIVIKEPKK---PPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE 1253
G C+ + +KEP P + Q + TV + ++G+ P +++W K E
Sbjct: 2773 GDDACSGILTVKEPPSFLVKPEWQQAIPDSTV------EFKAVLKGTPPFKVKWFKDDVE 2826
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
+ +C T+ L V + G Y C+ +N GSD+ + +
Sbjct: 2827 LASGPKCFIGLEGSTSFLNLYSVDASKTGQYTCQVTNDVGSDSCTTML------------ 2874
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEK-TTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIH 1610
V FV + ++ ++V+ +A K+ G P V W + + +L + +
Sbjct: 2875 ---LVTEPPKFVKKLEASKIVKAGDSARLECKITGSPEIRVVWYRNE-HELLPSDKYRMA 2930
Query: 1611 QKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A L++ DSG + C A N G + + V E
Sbjct: 2931 FIDSVAVLQMNSLGTEDSGDFICEAQNPAGSTSCSTKVIVKE 2972
Score = 273 bits (699), Expect = 2e-73
Identities = 176/579 (30%), Positives = 269/579 (46%), Gaps = 1/579 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+ V L+CQ+ ++ V+W K KL P YK++F + +A+L DS
Sbjct: 1117 PVQSAVNKKVHLECQVDEDRKVTVTWSKNGQKLPPGKDYKIYFEDKIASLEIPLAKLKDS 1176
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-GLPVVFECAVSGSEPIS 359
G Y+C A N G SSS +T++E PPSF +++ + G C + GS I
Sbjct: 1177 GTYVCTASNEAGSSSSSATVTIRE---PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQ 1233
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V+WFK+ + L + I+ SF+++ A L+I +G YSC A N +GS S SA +++
Sbjct: 1234 VTWFKNNKELNESNTIRMSFVNSEAVLDITDVKVEDSGSYSCEAVNDVGSDSCSAEIVIK 1293
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E PP F L P D V G +A +C ++GT P +++W KD ++IRS Y++ ++
Sbjct: 1294 E---PPSFIKTLEPADIVRGTNALLQCEISGTGPFEISWFKDKKQIRSSKKYRLFAQKSL 1350
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L I + D G+Y C NEVGK C A +KE PP+F KK+ + G +
Sbjct: 1351 VSLEIFSFNSADVGEYECVVANEVGKCGCLATHLLKE---PPTFVKKVDD-FTALAGQTV 1406
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L+ V GS+PISV W K I +++F N +L + + G YTC N+
Sbjct: 1407 TLQAAVRGSEPISVTWMKGQEIIKEDGKIKMSFTNGVAVLIIPDVQISLGGKYTCLAENE 1466
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
AGS +++KEP K + + V+ G+ L V G+ ++ +W K GR +
Sbjct: 1467 AGSQTSVGELIVKEPAK---IIERAELIQVTAGDPATLEYTVTGTPELKPKWYKDGRPLV 1523
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
S + SF N A L+F D+G Y + SN GS + +
Sbjct: 1524 ASKKYRLSFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSYR----------------- 1566
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
D FF +++ + T K+ G V W K +++ R I
Sbjct: 1567 ---DIAPFFTKPLRNVDSIVSGTCRLDCKIAGSLPMRVSWFK-DGKEVTSSDRYRIAFVE 1622
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
A LEI D+G + C A N G + + L V E
Sbjct: 1623 GTASLEISRVDMNDAGNFTCRATNSVGSKDCSGALIVQE 1661
Score = 267 bits (682), Expect = 2e-71
Identities = 176/581 (30%), Positives = 259/581 (44%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV+V +G A C++ P + W+K ++ + + N V TL + D
Sbjct: 929 PVEVALGHLAKFTCEIHSAPNVRFQWFKAGREIYESDKCSIRSANYVTTLEILRTQVVDC 988
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C+A N G VS + LTV E PP+F + + + VG F C V+G+ I
Sbjct: 989 GEYTCKASNEFGSVSCTATLTVTEA-YPPTFYSRPKSITTFVGKAAKFLCTVTGTPVIET 1047
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W KDG L PN + S DN L + G YSC A+N G+ A LI+ +
Sbjct: 1048 IWQKDGVALSPSPNCKISDADNKHILELSNLTVQDRGVYSCKASNKFGADICQAELIIID 1107
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L PV + V + EC V + + V W+K+ +++ G +Y+I + + A
Sbjct: 1108 ---KPHFIKELEPVQSAVNKKVHLECQVDEDRKVTVTWSKNGQKLPPGKDYKIYFEDKIA 1164
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I D+G Y C A NE G S +A + I+E PPSF KK+ + G S R
Sbjct: 1165 SLEIPLAKLKDSGTYVCTASNEAGSSSSSATVTIRE---PPSFVKKVDPSYLMLPGESAR 1221
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L ++ GS I V W+KNN E++ + ++F N+ +L + + D+G Y+C+ ND
Sbjct: 1222 LHCKLKGSPVIQVTWFKNNKELNESNTIRMSFVNSEAVLDITDVKVEDSGSYSCEAVNDV 1281
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
GS C++ IVIKE PP F + L P + G L C + G+ P I W K ++I+
Sbjct: 1282 GSDSCSAEIVIKE---PPSFIKTLEPADIVRGTNALLQCEISGTGPFEISWFKDKKQIRS 1338
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
S + LE AD G+Y C +N G
Sbjct: 1339 SKKYRLFAQKSLVSLEIFSFNSADVGEYECVVANEVGK---------------CGCLATH 1383
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
+ FV + + T T A V G +V W KG+ + + G+I +
Sbjct: 1384 LLKEPPTFVKKVDDFTALAGQTVTLQAAVRGSEPISVTWMKGQ-EIIKEDGKIKMSFTNG 1442
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKK 1745
A L I D + G Y C+A N+ G S L V E K
Sbjct: 1443 VAVLIIPDVQISLGGKYTCLAENEAGSQTSVGELIVKEPAK 1483
Score = 255 bits (652), Expect = 6e-68
Identities = 174/607 (28%), Positives = 279/607 (45%), Gaps = 2/607 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSND-SGEYIC 197
GD+ SL + E V+WY + +K N TLV + V+ + GEY C
Sbjct: 841 GDTISLASSITNAKE--VNWYFEGKLVPSDEKFKCLHDQNTYTLVIDHVNREEHEGEYTC 898
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKD 377
A N G+ ++S LTV + + P R++ V+ +G F C + + + WFK
Sbjct: 899 EASNDSGKAATSAKLTVVK-RAAPVIRRRIEPVEVALGHLAKFTCEIHSAPNVRFQWFKA 957
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
GR + + + V TL I +T G+Y+C A+N GS S +A L +TE P
Sbjct: 958 GREIYESDKCSIRSANYVTTLEILRTQVVDCGEYTCKASNEFGSVSCTATLTVTEAYPPT 1017
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F+ P + + VG++A F C VTGT I+ W KD + N +IS +N L +
Sbjct: 1018 FYSRPKS-ITTFVGKAAKFLCTVTGTPVIETIWQKDGVALSPSPNCKISDADNKHILELS 1076
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
+ D G Y+C A N+ G D C A+L I ++ P F K+L E V+ LE +V
Sbjct: 1077 NLTVQDRGVYSCKASNKFGADICQAELIIIDK---PHFIKEL-EPVQSAVNKKVHLECQV 1132
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
+ ++V W KN ++ P + +I F++ L++ A + D+G Y C SN+AGS+
Sbjct: 1133 DEDRKVTVTWSKNGQKLPPGKDYKIYFEDKIASLEIPLAKLKDSGTYVCTASNEAGSSSS 1192
Query: 1098 TSSIVIKEPKKPPVFDQHLTP-VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRC 1274
++++ I+E PP F + + P + GE +L C ++GS I++ W K +E+ S+
Sbjct: 1193 SATVTIRE---PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELNESNTI 1249
Query: 1275 SFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDG 1454
SF N AVL+ DV D+G Y C+A N GSD+ +++ +
Sbjct: 1250 RMSFVNSEAVLDITDVKVEDSGSYSCEAVNDVGSDSCSAEIV---------------IKE 1294
Query: 1455 KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKL 1634
F+ + +V T A ++ G + W K K +Q+ + + + L
Sbjct: 1295 PPSFIKTLEPADIVRGTNALLQCEISGTGPFEISWFKDK-KQIRSSKKYRLFAQKSLVSL 1353
Query: 1635 EIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAG 1814
EI D G Y CV N+ G+ + E K D A+ +T L+
Sbjct: 1354 EIFSFNSADVGEYECVVANEVGKCGCLATHLLKEPPTFVKKVDDFTALAGQTVTLQAAVR 1413
Query: 1815 EEEEIDI 1835
E I +
Sbjct: 1414 GSEPISV 1420
Score = 116 bits (291), Expect = 4e-26
Identities = 80/287 (27%), Positives = 125/287 (43%), Gaps = 1/287 (0%)
Frame = +3
Query: 843 PSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQ 1022
P L++T+ E EG++ L + ++ ++ WY + + N L
Sbjct: 827 PVILTPLADTIAE-EGDTISLASSITNAKEVN--WYFEGKLVPSDEKFKCLHDQNTYTLV 883
Query: 1023 VKKASMGD-AGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSC 1199
+ + + G YTC+ SND+G A ++ + + + + PV + + PV V+ G + +C
Sbjct: 884 IDHVNREEHEGEYTCEASNDSGKAATSAKLTVVK-RAAPVIRRRIEPVEVALGHLAKFTC 942
Query: 1200 HVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSD 1379
+ + +R QW KAGREI SD+CS AN LE D G+Y CKASN GS
Sbjct: 943 EIHSAPNVRFQWFKAGREIYESDKCSIRSANYVTTLEILRTQVVDCGEYTCKASNEFGSV 1002
Query: 1380 TSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW 1559
+ + +T F S P+SI A F+ V G P+ W
Sbjct: 1003 SCTATLTVTEAYPPT-------------FYSRPKSITTFVGKAAKFLCTVTGTPVIETIW 1049
Query: 1560 TKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG 1700
K L+ I ++ LE+ + T D G+Y C A NK G
Sbjct: 1050 QK-DGVALSPSPNCKISDADNKHILELSNLTVQDRGVYSCKASNKFG 1095
Score = 89.7 bits (221), Expect = 5e-18
Identities = 59/199 (29%), Positives = 86/199 (43%), Gaps = 23/199 (11%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
++ VGD A L + G P + W+ L P+A YK F N +L+ S D GE
Sbjct: 66 EINVGDVAKLSVTVTGIPRPKIQWFFNGVMLIPSADYKFVFDGNDHSLIILFTKSGDEGE 125
Query: 189 YICRAENSVGEVSSSTFLTVQ--------------------EQKLPPSFSRQLRDVQETV 308
Y C A N G+ + S +L + E PP FS+ L+ V
Sbjct: 126 YTCTASNEHGQATCSAYLKINSKGEEHKEPESAEEKSLEKLEGPCPPYFSKTLKPVHCAQ 185
Query: 309 GLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFL---DNVATLNIFQTDRSFAGQY 479
GLP VFE V G +V WFK+ + L N+ + + D T + + +G Y
Sbjct: 186 GLPAVFEYTVLGEPAPTVLWFKENKQL--CTNVYYTVIHHPDGSGTFIVNDPQKEDSGLY 243
Query: 480 SCTATNPIGSASSSARLIL 536
C A N G +S+A L++
Sbjct: 244 VCKAENVWGETTSAAELLV 262
Score = 72.0 bits (175), Expect = 1e-12
Identities = 61/220 (27%), Positives = 92/220 (41%), Gaps = 21/220 (9%)
Frame = +3
Query: 222 VSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGP 401
V S F + +E +P F ++ + + VG V+G + WF +G L
Sbjct: 42 VCSVNFSSKKEGSVP-IFIKEASNAEINVGDVAKLSVTVTGIPRPKIQWFFNGVMLIPSA 100
Query: 402 NIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT-------------- 539
+ + F N +L I T G+Y+CTA+N G A+ SA L +
Sbjct: 101 DYKFVFDGNDHSLIILFTKSGDEGEYTCTASNEHGQATCSAYLKINSKGEEHKEPESAEE 160
Query: 540 ------EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQ- 698
EG PP+F L PV G A FE V G V W K+N+++ + Y
Sbjct: 161 KSLEKLEGPCPPYFSKTLKPVHCAQGLPAVFEYTVLGEPAPTVLWFKENKQLCTNVYYTV 220
Query: 699 ISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQL 818
I + + S + K D+G Y C A N G+ + A+L
Sbjct: 221 IHHPDGSGTFIVNDPQKEDSGLYVCKAENVWGETTSAAEL 260
Score = 66.2 bits (160), Expect = 6e-11
Identities = 57/221 (25%), Positives = 80/221 (36%), Gaps = 8/221 (3%)
Frame = +3
Query: 1092 LCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDR 1271
+C+ + K+ P+F + + ++ G+ +LS V G +IQW G + PS
Sbjct: 42 VCSVNFSSKKEGSVPIFIKEASNAEINVGDVAKLSVTVTGIPRPKIQWFFNGVMLIPSAD 101
Query: 1272 CSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTS------KSKVTXXXXXXXXXXX 1433
F F L D G+Y C ASN G T SK
Sbjct: 102 YKFVFDGNDHSLIILFTKSGDEGEYTCTASNEHGQATCSAYLKINSKGEEHKEPESAEEK 161
Query: 1434 XXXXVDGKL--FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFI 1607
++G +F + + + A F V G+P P V W K + I
Sbjct: 162 SLEKLEGPCPPYFSKTLKPVHCAQGLPAVFEYTVLGEPAPTVLWFKENKQLCTNVYYTVI 221
Query: 1608 HQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
H + D K DSGLY C A N GE S L V
Sbjct: 222 HHPDGSGTFIVNDPQKEDSGLYVCKAENVWGETTSAAELLV 262
Score = 64.3 bits (155), Expect = 2e-10
Identities = 54/208 (25%), Positives = 81/208 (38%), Gaps = 21/208 (10%)
Frame = +3
Query: 555 PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTI 734
P F + + VG+ A VTG K+ W + + +Y+ + N L I
Sbjct: 56 PIFIKEASNAEINVGDVAKLSVTVTGIPRPKIQWFFNGVMLIPSADYKFVFDGNDHSLII 115
Query: 735 LKVDKGDTGQYTCYAVNEVGKDSCTAQLNIK--------------------ERLIPPSFT 854
L GD G+YTC A NE G+ +C+A L I E PP F+
Sbjct: 116 LFTKSGDEGEYTCTASNEHGQATCSAYLKINSKGEEHKEPESAEEKSLEKLEGPCPPYFS 175
Query: 855 KKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTA-NCEITFKNNALLLQVKK 1031
K L + V +G E V G +V W+K N ++ I + + V
Sbjct: 176 KTL-KPVHCAQGLPAVFEYTVLGEPAPTVLWFKENKQLCTNVYYTVIHHPDGSGTFIVND 234
Query: 1032 ASMGDAGLYTCKVSNDAGSALCTSSIVI 1115
D+GLY CK N G + +++
Sbjct: 235 PQKEDSGLYVCKAENVWGETTSAAELLV 262
>ref|XP_003359623.1| PREDICTED: titin-like, partial [Sus scrofa].
Length = 1746
Score = 224 bits (571), Expect = 1e-58
Identities = 113/128 (88%), Positives = 113/128 (88%)
Frame = +3
Query: 1116 KEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANG 1295
KEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANG
Sbjct: 1619 KEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANG 1678
Query: 1296 TAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSE 1475
TAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT VDGKLFFVSE
Sbjct: 1679 TAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTIKDKPAAIPAAKKAAVDGKLFFVSE 1738
Query: 1476 PQSIRVVE 1499
PQSIRVVE
Sbjct: 1739 PQSIRVVE 1746
Score = 132 bits (331), Expect = 9e-31
Identities = 65/65 (100%), Positives = 65/65 (100%)
Frame = +3
Query: 1776 MLKKTPVLKKGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEE 1955
MLKKTPVLKKGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEE
Sbjct: 1 MLKKTPVLKKGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFEMLKQSQEE 60
Query: 1956 ETHRL 1970
ETHRL
Sbjct: 61 ETHRL 65
Score = 77.0 bits (188), Expect = 4e-14
Identities = 80/325 (24%), Positives = 132/325 (40%), Gaps = 3/325 (0%)
Frame = +3
Query: 864 SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMG 1043
++TV + + F ++ ++ + I ++WYK ++ P+ EI+ + L+VK +
Sbjct: 105 NQTVLKDDDAVFEIDIKINYPE-IKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLK 163
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEP- 1220
D G Y SA T VI+ P +++HL VT+ EG+ ++C S P
Sbjct: 164 DQGNYRLVCGPHIASAKLT---VIE-----PAWERHLQDVTLKEGQTCTMTCQF--SVPN 213
Query: 1221 IRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
++ +W + GR +KP R + L DV D G Y CK ++ S + +
Sbjct: 214 VKSEWFRNGRILKPQGRYKTEVEHKVHKLTIADVRAEDQGRYTCKYEDLETSADLRIEAE 273
Query: 1401 XXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQ 1580
+ F Q+I V E +ATF +V D V W KG +
Sbjct: 274 ------------------PIQFTRRIQNIVVSEHQSATFECEVSFDD-AIVTWYKGP-TE 313
Query: 1581 LNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVA-FNKHGEIESNVNLQVNERK-KQEK 1754
L + + G + I + T D G+Y +A GE S L + ++ K E
Sbjct: 314 LTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLEM 373
Query: 1755 IEGDLRAMLKKTPVLKKGAGEEEEI 1829
D+ P + A EEI
Sbjct: 374 KPPDIPDSRVPIPTMPIRAVPPEEI 398
Score = 76.6 bits (187), Expect = 5e-14
Identities = 36/98 (36%), Positives = 50/98 (51%)
Frame = +3
Query: 540 EGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
E + PP FD L PV GE CHV G++PI++ W K REI+ S+ +
Sbjct: 1620 EPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGT 1679
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKER 833
A L V K D G Y C A N G D+ +++ IK++
Sbjct: 1680 AVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTIKDK 1717
Score = 73.6 bits (179), Expect = 4e-13
Identities = 76/270 (28%), Positives = 106/270 (39%), Gaps = 8/270 (2%)
Frame = +3
Query: 60 PEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY--ICRAENSVGEVSSS 233
PEI +SWYKG KL P+ +++ + TL D G Y +C G +S
Sbjct: 125 PEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC------GPHIAS 178
Query: 234 TFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQT 413
LTV E P++ R L+DV G C S + WF++GR LK +T
Sbjct: 179 AKLTVIE----PAWERHLQDVTLKEGQTCTMTCQFSVPN-VKSEWFRNGRILKPQGRYKT 233
Query: 414 SFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAV 593
V L I G+Y+C + SA L P F + +
Sbjct: 234 EVEHKVHKLTIADVRAEDQGRYTCKYEDLETSAD------LRIEAEPIQFTRRIQNIVVS 287
Query: 594 VGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTC 773
+SA FEC V+ I V W K E+ Y ++TI V D G Y+
Sbjct: 288 EHQSATFECEVSFDDAI-VTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSV 346
Query: 774 YA-VNEVGKDSCTAQL-----NIKERLIPP 845
A + G+ TA+L IK + PP
Sbjct: 347 IARLEPRGEARSTAELYLTTKEIKLEMKPP 376
Score = 71.2 bits (173), Expect = 2e-12
Identities = 39/99 (39%), Positives = 52/99 (52%)
Frame = +3
Query: 825 KERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKN 1004
KE PP F + L+ V +EG +L V GS+PI + W K EI P+ C +F N
Sbjct: 1619 KEPKKPPVFDQHLTP-VTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFAN 1677
Query: 1005 NALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKE 1121
+L+ K + DAG Y CK SN AGS S + IK+
Sbjct: 1678 GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTIKD 1716
Score = 64.3 bits (155), Expect = 2e-10
Identities = 33/98 (33%), Positives = 49/98 (50%)
Frame = +3
Query: 249 QEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDN 428
+E K PP F + L V + G + C V GSEPI + W K GR +K SF +
Sbjct: 1619 KEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANG 1678
Query: 429 VATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
A L ++ AG Y C A+N GS +S +++ + +
Sbjct: 1679 TAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTIKD 1716
Score = 61.6 bits (148), Expect = 2e-09
Identities = 26/85 (30%), Positives = 46/85 (54%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
PV V+ G+ L C + G+ I + W K +++P+ F N A L F V D+
Sbjct: 1633 PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADA 1692
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQ 257
G+Y+C+A N G +S + +T++++
Sbjct: 1693 GDYVCKASNVAGSDTSKSKVTIKDK 1717
>ref|XP_003123677.2| PREDICTED: LOW QUALITY PROTEIN: obscurin [Sus scrofa].
Length = 8093
Score = 155 bits (392), Expect = 8e-38
Identities = 149/560 (26%), Positives = 233/560 (41%), Gaps = 2/560 (0%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVAT--LVFNQVDSNDS 182
+ T G SA+L C+L+ V W KG LR A ++ R + AT L + D+
Sbjct: 3095 EATEGASATLHCELSKAAP--VEWRKGSETLR--AGDRVILRQDGATCELEIRGLTVADA 3150
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C G+ +S LTV+ LP F++ LR + T G C +S + P V
Sbjct: 3151 GEYSCVC----GQEKTSATLTVRA--LPAKFTKGLRKEEATEGASATLHCELSKAAP--V 3202
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W K L+ G + L I + AG+YSC SA+ + R +
Sbjct: 3203 EWRKGSETLRAGDRVILRQDGATCELEIRGLTVADAGEYSCVCGQEKTSATLTVRAL--- 3259
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L +A G SA C ++ P++ W K + +R+G + +
Sbjct: 3260 ---PAKFTKGLRKEEATEGASATLHCELSKAAPVE--WRKGSETLRAGDRVILRQDGATC 3314
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I + D G+Y+C G++ +A L + R +P FTK L + E TEG S
Sbjct: 3315 ELEIRGLTVADAGEYSCVC----GQEKTSATLTV--RALPAKFTKGLRKE-EATEGASAT 3367
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L ++ + P+ W K + + + L+++ ++ DAG Y+C +
Sbjct: 3368 LHCELSKAAPVE--WRKGSETLRAGDRVILRQDGATCELEIRGLTVADAGEYSCVCGQEK 3425
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
SA T + P F + L +EG L C + + P+ +W K ++
Sbjct: 3426 TSATLTVRAL------PAKFTKGLRKEEATEGASATLHCELSKAAPV--EWRKGSETLRA 3477
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
DR T LE + +T ADAG+Y C V G + + + +T
Sbjct: 3478 GDRVILRQDGATCELEIRGLTVADAGEYSC----VCGQEKTSAALTVRALPAE------- 3526
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
F+ +S +E TTAT ++ + V+W KG L G R+ + Q G
Sbjct: 3527 -------FIRRLRSKEFMEGTTATLHCELSKE--APVEWRKGP-ETLRAGDRVSLRQDGV 3576
Query: 1623 EAKLEIRDTTKTDSGLYRCV 1682
+LEIR D+G Y CV
Sbjct: 3577 MCELEIRGLMVADAGEYSCV 3596
Score = 155 bits (391), Expect = 1e-37
Identities = 145/568 (25%), Positives = 237/568 (41%), Gaps = 8/568 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ G S +L C++A + V+WYK KL ++ + + LV QV D+G
Sbjct: 14 VQAKAGASTTLSCEVAQA-QTEVTWYKDGKKLSASSKVHVEAKGCTRRLVVQQVGKADAG 72
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQ---LRDVQETVGLPVVFECAVSGSEPI 356
EY C A G S L V E + F+++ +VQ G C V+ ++
Sbjct: 73 EYSCEA----GGQKVSFHLDVTEPSV--VFAKEQLACSEVQAMAGASATLSCEVAQAQ-T 125
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
V+W+KDG+ L ++ L + Q ++ AG+YSC A G S L +
Sbjct: 126 EVTWYKDGKKLSSSSKVRVEAKGCNRRLVVQQVGKADAGEYSCEA----GGQKVSFHLDV 181
Query: 537 TEGRNPPFFDIPL-APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
TE + P V A+ G SA C V Q +V W KD +++ S ++
Sbjct: 182 TEPSVVFAKEQPARTEVQAMAGASATLSCEVAQAQ-TEVTWYKDGKKLTSSSKVRVEAKG 240
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN 893
+ L + + K D G+Y+C E G + L+I E + + + S V+ G
Sbjct: 241 CNRRLVVQQAGKADAGEYSC----EAGGQKVSFHLDITEPSVVFAKEQPSSSAVQAVTGA 296
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
S L VA +Q V WYK+ ++ ++ + K L V++A DAG Y+C
Sbjct: 297 SATLNCEVAQAQ-TEVTWYKDGKKLSSSSKVRVEAKGCTRRLVVQQAGKADAGEYSC--- 352
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQ-HLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
+AG + + + +P +Q T V G L+C V ++ + W K G+
Sbjct: 353 -EAGGQKVSFHLDVTDPSVVFAKEQPACTEVQAMAGASATLNCEVAQAQ-TEVTWYKDGK 410
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
++ S + T L + KADAG+Y CKA KV+
Sbjct: 411 KLSSSSKVHVEAKGCTRRLVVQQAGKADAGEYSCKAGG--------QKVS---------- 452
Query: 1431 XXXXXVDGKLFFVSEPQS---IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRI 1601
+ + F E +S ++ V +AT +V V W K ++L+ ++
Sbjct: 453 FHLDVTEPSVVFAKEQKSYSEVQAVAGASATLSCEV-AQAQTEVTWYK-DGKKLSSSSKV 510
Query: 1602 FIHQKGDEAKLEIRDTTKTDSGLYRCVA 1685
+ KG +L ++ K D+G Y C A
Sbjct: 511 RVEAKGCTRRLVVQQAVKADAGEYSCEA 538
Score = 154 bits (388), Expect = 2e-37
Identities = 145/568 (25%), Positives = 238/568 (41%), Gaps = 8/568 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ G SA+L C++A + V+WYK KL ++ ++ + LV QV D+G
Sbjct: 106 VQAMAGASATLSCEVAQA-QTEVTWYKDGKKLSSSSKVRVEAKGCNRRLVVQQVGKADAG 164
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR-DVQETVGLPVVFECAVSGSEPISV 362
EY C A G S L V E + + + R +VQ G C V+ ++ V
Sbjct: 165 EYSCEA----GGQKVSFHLDVTEPSVVFAKEQPARTEVQAMAGASATLSCEVAQAQT-EV 219
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W+KDG+ L ++ L + Q ++ AG+YSC A G S L +TE
Sbjct: 220 TWYKDGKKLTSSSKVRVEAKGCNRRLVVQQAGKADAGEYSCEA----GGQKVSFHLDITE 275
Query: 543 GRNPPFFDIPLAP-VDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
+ P + V AV G SA C V Q +V W KD +++ S ++ +
Sbjct: 276 PSVVFAKEQPSSSAVQAVTGASATLNCEVAQAQT-EVTWYKDGKKLSSSSKVRVEAKGCT 334
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L + + K D G+Y+C E G + L++ + + + + V+ G S
Sbjct: 335 RRLVVQQAGKADAGEYSC----EAGGQKVSFHLDVTDPSVVFAKEQPACTEVQAMAGASA 390
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L VA +Q V WYK+ ++ ++ + K L V++A DAG Y+CK
Sbjct: 391 TLNCEVAQAQT-EVTWYKDGKKLSSSSKVHVEAKGCTRRLVVQQAGKADAGEYSCK---- 445
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQH-LTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREI 1256
AG + + + EP +Q + V G LSC V ++ + W K G+++
Sbjct: 446 AGGQKVSFHLDVTEPSVVFAKEQKSYSEVQAVAGASATLSCEVAQAQT-EVTWYKDGKKL 504
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGS---DTSKSKVTXXXXXXXXX 1427
S + T L + KADAG+Y C+A S D ++ V
Sbjct: 505 SSSSKVRVEAKGCTRRLVVQQAVKADAGEYSCEAGGQKVSFHLDVTEPSV---------- 554
Query: 1428 XXXXXXVDGKLFFVSEP--QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRI 1601
+F +P ++ V +AT +V V W K ++L+ ++
Sbjct: 555 ----------VFAKEQPACSEVQAVTGASATLNCEVA-QAQTEVTWYKDG-KKLSSSSKV 602
Query: 1602 FIHQKGDEAKLEIRDTTKTDSGLYRCVA 1685
+ KG +L ++ K D+G Y C A
Sbjct: 603 RVEAKGCTRRLVVQQAGKADAGEYSCEA 630
Score = 152 bits (385), Expect = 5e-37
Identities = 154/595 (25%), Positives = 242/595 (40%), Gaps = 10/595 (1%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVAT--LVFNQVDSNDS 182
+ T G SA+L C+L+ V W KG LR A ++ R + AT L + D+
Sbjct: 2831 EATEGASATLHCELSKAAP--VEWRKGSETLR--AGDRVILRQDGATCELEIRGLTVADA 2886
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C G+ +S LTV+ LP F++ LR + T G C +S + P V
Sbjct: 2887 GEYSCVC----GQEKTSATLTVRA--LPAKFTKGLRKEEATEGASATLHCELSKAAP--V 2938
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W K L+ G + L I + AG+YSC SA+ + R +
Sbjct: 2939 EWRKGSETLRAGDRVILRQDGATCELEIRGLTVADAGEYSCVCGQEKTSATLTVRAL--- 2995
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L +A G SA C ++ P++ W K + +R+G + +
Sbjct: 2996 ---PAKFTKGLRKEEATEGASATLHCELSKAAPVE--WRKGSETLRAGDRVILRQDGATC 3050
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I + D G+Y+C G++ +A L + R +P FTK L + E TEG S
Sbjct: 3051 ELEIRGLTVADAGEYSCVC----GQEKTSATLTV--RALPAKFTKGLRKE-EATEGASAT 3103
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L ++ + P+ W K + + + L+++ ++ DAG Y+C +
Sbjct: 3104 LHCELSKAAPVE--WRKGSETLRAGDRVILRQDGATCELEIRGLTVADAGEYSCVCGQEK 3161
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
SA T + P F + L +EG L C + + P+ +W K ++
Sbjct: 3162 TSATLTVRAL------PAKFTKGLRKEEATEGASATLHCELSKAAPV--EWRKGSETLRA 3213
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
DR T LE + +T ADAG+Y C V G + + + +T
Sbjct: 3214 GDRVILRQDGATCELEIRGLTVADAGEYSC----VCGQEKTSATLTVRALPAK------- 3262
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
F + E +AT ++ V+W KG L G R+ + Q G
Sbjct: 3263 -------FTKGLRKEEATEGASATLHCEL--SKAAPVEWRKGS-ETLRAGDRVILRQDGA 3312
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE--------RKKQEKIEG 1763
+LEIR T D+G Y CV G+ +++ L V +K+E EG
Sbjct: 3313 TCELEIRGLTVADAGEYSCVC----GQEKTSATLTVRALPAKFTKGLRKEEATEG 3363
Score = 152 bits (384), Expect = 7e-37
Identities = 147/560 (26%), Positives = 229/560 (40%), Gaps = 2/560 (0%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVAT--LVFNQVDSNDS 182
+ T G SA+L C+L+ V W KG LR A ++ R + AT L + D+
Sbjct: 3007 EATEGASATLHCELSKAAP--VEWRKGSETLR--AGDRVILRQDGATCELEIRGLTVADA 3062
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C G+ +S LTV+ LP F++ LR + T G C +S + P V
Sbjct: 3063 GEYSCVC----GQEKTSATLTVRA--LPAKFTKGLRKEEATEGASATLHCELSKAAP--V 3114
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W K L+ G + L I + AG+YSC SA+ + R +
Sbjct: 3115 EWRKGSETLRAGDRVILRQDGATCELEIRGLTVADAGEYSCVCGQEKTSATLTVRAL--- 3171
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L +A G SA C ++ P++ W K + +R+G + +
Sbjct: 3172 ---PAKFTKGLRKEEATEGASATLHCELSKAAPVE--WRKGSETLRAGDRVILRQDGATC 3226
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I + D G+Y+C G++ +A L + R +P FTK L + E TEG S
Sbjct: 3227 ELEIRGLTVADAGEYSCVC----GQEKTSATLTV--RALPAKFTKGLRKE-EATEGASAT 3279
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L ++ + P+ W K + + + L+++ ++ DAG Y+C +
Sbjct: 3280 LHCELSKAAPVE--WRKGSETLRAGDRVILRQDGATCELEIRGLTVADAGEYSCVCGQEK 3337
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
SA T + P F + L +EG L C + + P+ +W K ++
Sbjct: 3338 TSATLTVRAL------PAKFTKGLRKEEATEGASATLHCELSKAAPV--EWRKGSETLRA 3389
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
DR T LE + +T ADAG+Y C V G + + + +T
Sbjct: 3390 GDRVILRQDGATCELEIRGLTVADAGEYSC----VCGQEKTSATLTVRALPAK------- 3438
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
F + E +AT ++ V+W KG L G R+ + Q G
Sbjct: 3439 -------FTKGLRKEEATEGASATLHCEL--SKAAPVEWRKGS-ETLRAGDRVILRQDGA 3488
Query: 1623 EAKLEIRDTTKTDSGLYRCV 1682
+LEIR T D+G Y CV
Sbjct: 3489 TCELEIRGLTVADAGEYSCV 3508
Score = 149 bits (376), Expect = 6e-36
Identities = 126/456 (27%), Positives = 198/456 (43%), Gaps = 5/456 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ G SA+L C++A + V+WYK KL ++ ++ + LV Q D+G
Sbjct: 474 VQAVAGASATLSCEVAQA-QTEVTWYKDGKKLSSSSKVRVEAKGCTRRLVVQQAVKADAG 532
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQ---LRDVQETVGLPVVFECAVSGSEPI 356
EY C A G S L V E + F+++ +VQ G C V+ ++
Sbjct: 533 EYSCEA----GGQKVSFHLDVTEPSVV--FAKEQPACSEVQAVTGASATLNCEVAQAQT- 585
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
V+W+KDG+ L ++ L + Q ++ AG+YSC A G S L +
Sbjct: 586 EVTWYKDGKKLSSSSKVRVEAKGCTRRLVVQQAGKADAGEYSCEA----GGQKVSFHLDV 641
Query: 537 TEGRNPPFFDIPL-APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLE 713
TE + P V AV G SA C V Q +V W KD +++ SG ++
Sbjct: 642 TEPLVAFAKEQPARTEVQAVTGASATLTCDVAQAQT-EVTWYKDGKKLTSGSKVRVEAKG 700
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN 893
+ L + + K D G+Y+C E G + L++ E + + + V+ G
Sbjct: 701 CTRRLVVQQAGKADAGEYSC----EAGGQKVSFHLDVTEPMEVFAKEQPACSEVQAMAGA 756
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
S L VA +Q V WYK+ ++ ++ + K L V +A DAG YTCK
Sbjct: 757 SATLSCEVAQAQT-EVTWYKDGKKLTSSSKVHVEAKGCTRRLMVHQAGKADAGEYTCK-- 813
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLT-PVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
AG + + + EP +Q + V G LSC V ++ + W K G+
Sbjct: 814 --AGGQKVSFHLDVTEPMVVFAKEQLMRREVQAKAGASTTLSCEVAQAQT-EVTWYKDGK 870
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKA 1358
++ S + T L + V KADAG+Y C+A
Sbjct: 871 KLSASSKVHVEAKGCTRRLVVQQVGKADAGEYSCEA 906
Score = 146 bits (369), Expect = 4e-35
Identities = 146/594 (24%), Positives = 234/594 (39%), Gaps = 8/594 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+++ G +A+L+C L+ + V W GD L+P Y + + LV + D+G
Sbjct: 2402 MEILEGGAATLRCMLSSVA-MPVEWRCGDEVLKPGGKYSLRQEGTMLELVVRDLRPQDTG 2460
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y C G+ +S LTV+ LP F +LR + G+ C +S P V
Sbjct: 2461 QYCC----CFGDQMTSAKLTVKA--LPAEFIGRLRSKEAKEGVTATLRCELSKEAP--VE 2512
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W K L+ G + V L I + AG+YSC G +SA L +T
Sbjct: 2513 WKKGPETLRAGGRVSLKQEGAVCELEIQDLTVADAGEYSCVC----GQERTSATLTVTA- 2567
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P F L + + G +A C ++ P++ W K +R+G +
Sbjct: 2568 -LPAEFIRRLRSKEFMEGTTATLHCELSKEAPVE--WRKGPETLRAGDRVSLRQDGVMCE 2624
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L I + D G+Y+C G++ +A L ++ +P FTK L + E TEG S L
Sbjct: 2625 LEIRGLMVADAGEYSCVC----GQERTSASLTVQA--LPAKFTKGLRKE-EATEGASATL 2677
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAG 1085
++ + P+ W K + + + L+++ ++ DAG Y+C +
Sbjct: 2678 HCELSKAAPVE--WRKGSETLRAGDRVILRQDGATCELEIRGLTVADAGEYSCVCGQEKT 2735
Query: 1086 SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS 1265
SA T + P F + L +EG L C + + P+ +W K ++
Sbjct: 2736 SATLTVRAL------PAKFTKGLRKEEATEGASATLHCELSKAAPV--EWRKGSETLRAG 2787
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
DR T LE + +T ADAG+Y C
Sbjct: 2788 DRVILRQDGATCELEIRGLTVADAGEYSC------------------------------- 2816
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDE 1625
V F + E +AT ++ V+W KG L G R+ + Q G
Sbjct: 2817 VSLPAKFTKGLRKEEATEGASATLHCEL--SKAAPVEWRKGS-ETLRAGDRVILRQDGAT 2873
Query: 1626 AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE--------RKKQEKIEG 1763
+LEIR T D+G Y CV G+ +++ L V +K+E EG
Sbjct: 2874 CELEIRGLTVADAGEYSCVC----GQEKTSATLTVRALPAKFTKGLRKEEATEG 2923
Score = 145 bits (366), Expect = 8e-35
Identities = 151/595 (25%), Positives = 237/595 (39%), Gaps = 10/595 (1%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVAT--LVFNQVDSNDS 182
+ T G SA+L C+L+ V W KG LR A ++ R + AT L + D+
Sbjct: 2668 EATEGASATLHCELSKAAP--VEWRKGSETLR--AGDRVILRQDGATCELEIRGLTVADA 2723
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C G+ +S LTV+ LP F++ LR + T G C +S + P V
Sbjct: 2724 GEYSCVC----GQEKTSATLTVRA--LPAKFTKGLRKEEATEGASATLHCELSKAAP--V 2775
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W K L+ G + L I + AG+YSC +
Sbjct: 2776 EWRKGSETLRAGDRVILRQDGATCELEIRGLTVADAGEYSCVSL---------------- 2819
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L +A G SA C ++ P++ W K + +R+G + +
Sbjct: 2820 ---PAKFTKGLRKEEATEGASATLHCELSKAAPVE--WRKGSETLRAGDRVILRQDGATC 2874
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I + D G+Y+C G++ +A L + R +P FTK L + E TEG S
Sbjct: 2875 ELEIRGLTVADAGEYSCVC----GQEKTSATLTV--RALPAKFTKGLRKE-EATEGASAT 2927
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L ++ + P+ W K + + + L+++ ++ DAG Y+C +
Sbjct: 2928 LHCELSKAAPVE--WRKGSETLRAGDRVILRQDGATCELEIRGLTVADAGEYSCVCGQEK 2985
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
SA T + P F + L +EG L C + + P+ +W K ++
Sbjct: 2986 TSATLTVRAL------PAKFTKGLRKEEATEGASATLHCELSKAAPV--EWRKGSETLRA 3037
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
DR T LE + +T ADAG+Y C V G + + + +T
Sbjct: 3038 GDRVILRQDGATCELEIRGLTVADAGEYSC----VCGQEKTSATLTVRALPAK------- 3086
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
F + E +AT ++ V+W KG L G R+ + Q G
Sbjct: 3087 -------FTKGLRKEEATEGASATLHCEL--SKAAPVEWRKGS-ETLRAGDRVILRQDGA 3136
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE--------RKKQEKIEG 1763
+LEIR T D+G Y CV G+ +++ L V +K+E EG
Sbjct: 3137 TCELEIRGLTVADAGEYSCVC----GQEKTSATLTVRALPAKFTKGLRKEEATEG 3187
Score = 144 bits (362), Expect = 2e-34
Identities = 146/589 (24%), Positives = 229/589 (38%), Gaps = 8/589 (1%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G +A+L C+L+ E V W KG LR + + L + D+GEY C
Sbjct: 2584 GTTATLHCELS--KEAPVEWRKGPETLRAGDRVSLRQDGVMCELEIRGLMVADAGEYSCV 2641
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDG 380
G+ +S LTVQ LP F++ LR + T G C +S + P V W K
Sbjct: 2642 C----GQERTSASLTVQA--LPAKFTKGLRKEEATEGASATLHCELSKAAP--VEWRKGS 2693
Query: 381 RPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPF 560
L+ G + L I + AG+YSC SA+ + R + P
Sbjct: 2694 ETLRAGDRVILRQDGATCELEIRGLTVADAGEYSCVCGQEKTSATLTVRAL------PAK 2747
Query: 561 FDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILK 740
F L +A G SA C ++ P++ W K + +R+G + + L I
Sbjct: 2748 FTKGLRKEEATEGASATLHCELSKAAPVE--WRKGSETLRAGDRVILRQDGATCELEIRG 2805
Query: 741 VDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVA 920
+ D G+Y+C + +P FTK L + E TEG S L ++
Sbjct: 2806 LTVADAGEYSCVS-------------------LPAKFTKGLRKE-EATEGASATLHCELS 2845
Query: 921 GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
+ P+ W K + + + L+++ ++ DAG Y+C + SA T
Sbjct: 2846 KAAPVE--WRKGSETLRAGDRVILRQDGATCELEIRGLTVADAGEYSCVCGQEKTSATLT 2903
Query: 1101 SSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSF 1280
+ P F + L +EG L C + + P+ +W K ++ DR
Sbjct: 2904 VRAL------PAKFTKGLRKEEATEGASATLHCELSKAAPV--EWRKGSETLRAGDRVIL 2955
Query: 1281 SFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKL 1460
T LE + +T ADAG+Y C V G + + + +T
Sbjct: 2956 RQDGATCELEIRGLTVADAGEYSC----VCGQEKTSATLTVRALPAK------------- 2998
Query: 1461 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEI 1640
F + E +AT ++ V+W KG L G R+ + Q G +LEI
Sbjct: 2999 -FTKGLRKEEATEGASATLHCEL--SKAAPVEWRKGS-ETLRAGDRVILRQDGATCELEI 3054
Query: 1641 RDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE--------RKKQEKIEG 1763
R T D+G Y CV G+ +++ L V +K+E EG
Sbjct: 3055 RGLTVADAGEYSCVC----GQEKTSATLTVRALPAKFTKGLRKEEATEG 3099
Score = 141 bits (356), Expect = 1e-33
Identities = 119/455 (26%), Positives = 194/455 (42%), Gaps = 5/455 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ G SA+L C++A + V+WYK KL ++ ++ + LV Q D+G
Sbjct: 566 VQAVTGASATLNCEVAQA-QTEVTWYKDGKKLSSSSKVRVEAKGCTRRLVVQQAGKADAG 624
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLR-DVQETVGLPVVFECAVSGSEPISV 362
EY C A G S L V E + + + R +VQ G C V+ ++ V
Sbjct: 625 EYSCEA----GGQKVSFHLDVTEPLVAFAKEQPARTEVQAVTGASATLTCDVAQAQT-EV 679
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W+KDG+ L G ++ L + Q ++ AG+YSC A G S L +TE
Sbjct: 680 TWYKDGKKLTSGSKVRVEAKGCTRRLVVQQAGKADAGEYSCEA----GGQKVSFHLDVTE 735
Query: 543 GRNPPFFDIP-LAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
+ P + V A+ G SA C V Q +V W KD +++ S + +
Sbjct: 736 PMEVFAKEQPACSEVQAMAGASATLSCEVAQAQ-TEVTWYKDGKKLTSSSKVHVEAKGCT 794
Query: 720 AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSF 899
L + + K D G+YTC A G + L++ E ++ + + + V+ G S
Sbjct: 795 RRLMVHQAGKADAGEYTCKA----GGQKVSFHLDVTEPMVVFAKEQLMRREVQAKAGAST 850
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
L VA +Q V WYK+ ++ ++ + K L V++ DAG Y+C +
Sbjct: 851 TLSCEVAQAQ-TEVTWYKDGKKLSASSKVHVEAKGCTRRLVVQQVGKADAGEYSC----E 905
Query: 1080 AGSALCTSSIVIKEPKKPPVF---DQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGR 1250
AG + + + EP+ + P+ V E E + L+ + + WLK G
Sbjct: 906 AGGQKVSFHLDVTEPEPELAALERPRRREPLVVKEHEDIVLTATLATPSVAAVTWLKDGV 965
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCK 1355
EI+ S R + T L D+ Y C+
Sbjct: 966 EIRRSKRHEMASLGETHTLTVHGAQTLDSAVYSCR 1000
Score = 139 bits (350), Expect = 6e-33
Identities = 141/556 (25%), Positives = 226/556 (40%), Gaps = 1/556 (0%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
+G+ L+C+L+ I V W K +R + Y++ A LV + D GEY C
Sbjct: 2048 LGEDVVLRCELS-REGIPVHWLKDGKAIRKSKKYEVLTEGTWAMLVVHAASLKDCGEYTC 2106
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKD 377
E+S S+ L ++E+ P F+ +L D+Q VF C SV+W K
Sbjct: 2107 ETESS----KSTASLHLEEK--PNRFTEELADLQVEEKGTAVFACKTE-RPAASVTWCKG 2159
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
L+ S L I +++ + Y+C IG A S ARL L +G+
Sbjct: 2160 LTELRASGKHMPSQEGLTLRLTISALEKADSDTYTCN----IGQAQSQARL-LVQGQKV- 2213
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH-LTI 734
F L + G SA F C ++ V W D + + +I H LT+
Sbjct: 2214 FIMEDLEDTEVQEGSSATFCCRISPADYKPVHWFLDKTPLYANELNEIEAQPGGYHVLTL 2273
Query: 735 LKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGR 914
++ D+G E G +A L + E+ P F+++L++ V TEG L
Sbjct: 2274 RQLALKDSGTVHF----EAGDQRASAALRVTEK--PSVFSQELTD-VTVTEGEDLTLVCE 2326
Query: 915 VAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSAL 1094
A V W K+ + P+A C T++ L + ++ D+G Y C+
Sbjct: 2327 TAALDN-PVCWTKDGKALRPSARCRQTYEGRRAQLVITDTTLQDSGRYKCETGG------ 2379
Query: 1095 CTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRC 1274
SS +++ +P F + L + + EG L C + S + ++W +KP +
Sbjct: 2380 AWSSSIVRVHARPVWFREGLKDMEILEGGAATLRCML-SSVAMPVEWRCGDEVLKPGGKY 2438
Query: 1275 SFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDG 1454
S L +D+ D G Y C G + +K+T
Sbjct: 2439 SLRQEGTMLELVVRDLRPQDTGQYCC----CFGDQMTSAKLTVKALPAE----------- 2483
Query: 1455 KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKL 1634
F+ +S E TAT ++ + V+W KG L GGR+ + Q+G +L
Sbjct: 2484 ---FIGRLRSKEAKEGVTATLRCELSKEA--PVEWKKGP-ETLRAGGRVSLKQEGAVCEL 2537
Query: 1635 EIRDTTKTDSGLYRCV 1682
EI+D T D+G Y CV
Sbjct: 2538 EIQDLTVADAGEYSCV 2553
Score = 135 bits (340), Expect = 8e-32
Identities = 136/562 (24%), Positives = 220/562 (39%), Gaps = 2/562 (0%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V VT G+ +L C+ A V W K LRP+A + + A LV DSG
Sbjct: 2313 VTVTEGEDLTLVCETAALDN-PVCWTKDGKALRPSARCRQTYEGRRAQLVITDTTLQDSG 2371
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
Y C G SS+ + V + P F L+D++ G C +S S + V
Sbjct: 2372 RYKCET----GGAWSSSIVRVHAR--PVWFREGLKDMEILEGGAATLRCMLS-SVAMPVE 2424
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W LK G + L + GQY C + + SA + + +
Sbjct: 2425 WRCGDEVLKPGGKYSLRQEGTMLELVVRDLRPQDTGQYCCCFGDQMTSAKLTVKAL---- 2480
Query: 546 RNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH 725
P F L +A G +A C ++ P++ W K +R+GG +
Sbjct: 2481 --PAEFIGRLRSKEAKEGVTATLRCELSKEAPVE--WKKGPETLRAGGRVSLKQEGAVCE 2536
Query: 726 LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRL 905
L I + D G+Y+C G++ +A L + +P F ++L + E EG + L
Sbjct: 2537 LEIQDLTVADAGEYSCVC----GQERTSATLTVTA--LPAEFIRRL-RSKEFMEGTTATL 2589
Query: 906 EGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALL--LQVKKASMGDAGLYTCKVSND 1079
++ P+ W K + A ++ + + ++ L+++ + DAG Y+C +
Sbjct: 2590 HCELSKEAPVE--WRKGPETLR--AGDRVSLRQDGVMCELEIRGLMVADAGEYSCVCGQE 2645
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
SA T + P F + L +EG L C + + P+ +W K ++
Sbjct: 2646 RTSASLTVQAL------PAKFTKGLRKEEATEGASATLHCELSKAAPV--EWRKGSETLR 2697
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXX 1439
DR T LE + +T ADAG+Y C V G + + + +T
Sbjct: 2698 AGDRVILRQDGATCELEIRGLTVADAGEYSC----VCGQEKTSATLTVRALPAK------ 2747
Query: 1440 XXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG 1619
F + E +AT ++ V+W KG L G R+ + Q G
Sbjct: 2748 --------FTKGLRKEEATEGASATLHCEL--SKAAPVEWRKGS-ETLRAGDRVILRQDG 2796
Query: 1620 DEAKLEIRDTTKTDSGLYRCVA 1685
+LEIR T D+G Y CV+
Sbjct: 2797 ATCELEIRGLTVADAGEYSCVS 2818
Score = 131 bits (330), Expect = 1e-30
Identities = 151/592 (25%), Positives = 244/592 (41%), Gaps = 8/592 (1%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVAT--LVFNQVDSNDS 182
+ T G SA+L C+L+ V W KG LR A ++ R + AT L + D+
Sbjct: 3271 EATEGASATLHCELSKAAP--VEWRKGSETLR--AGDRVILRQDGATCELEIRGLTVADA 3326
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C G+ +S LTV+ LP F++ LR + T G C +S + P V
Sbjct: 3327 GEYSCVC----GQEKTSATLTVRA--LPAKFTKGLRKEEATEGASATLHCELSKAAP--V 3378
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W K L+ G + L I + AG+YSC SA+ + R +
Sbjct: 3379 EWRKGSETLRAGDRVILRQDGATCELEIRGLTVADAGEYSCVCGQEKTSATLTVRAL--- 3435
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L +A G SA C ++ P++ W K + +R+G + +
Sbjct: 3436 ---PAKFTKGLRKEEATEGASATLHCELSKAAPVE--WRKGSETLRAGDRVILRQDGATC 3490
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I + D G+Y+C G++ +A L + R +P F ++L + E EG +
Sbjct: 3491 ELEIRGLTVADAGEYSCVC----GQEKTSAALTV--RALPAEFIRRL-RSKEFMEGTTAT 3543
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALL--LQVKKASMGDAGLYTCKVSN 1076
L ++ P+ W K + A ++ + + ++ L+++ + DAG Y+C
Sbjct: 3544 LHCELSKEAPVE--WRKGPETLR--AGDRVSLRQDGVMCELEIRGLMVADAGEYSCVCGQ 3599
Query: 1077 DAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQ-WLKAGRE 1253
+ SA T K VF + L + EG L C + SEP I W K G E
Sbjct: 3600 ERTSATLTVQ------GKDCVFRKPLQSLQAEEGNSASLRCEL--SEPSSIVVWSKGGLE 3651
Query: 1254 IKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXX 1433
++ R A L +D+ + DAG+Y C GS + + +T
Sbjct: 3652 LQADRRREPQQRGHIAELVLRDLRREDAGEYTC----TCGSQATSATLT----------- 3696
Query: 1434 XXXXVDGKLFFVSEPQSIRVVEKTTATF---IAKVGGDPIPNVKWTKGKWRQLNQGGRIF 1604
+ F+ E Q+ V E TA +++ G +V+W KG QL +
Sbjct: 3697 ---VTAAPVRFLQELQAQEVDEGATAHLRCELSRAGA----SVEWRKGS-LQLFPCAKYQ 3748
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQEKIE 1760
+ +G A+L + + D+G Y C G ++S +L V + K E
Sbjct: 3749 MVLEGTTAELLVHGAEQEDAGHYTC----DTGHMQSTASLSVRALQPVFKTE 3796
Score = 130 bits (326), Expect = 4e-30
Identities = 149/592 (25%), Positives = 244/592 (41%), Gaps = 3/592 (0%)
Frame = +3
Query: 36 LQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICRAENSV 215
L+CQ++ V W+KG +L+P A Y+M LV N V D Y C A
Sbjct: 1517 LECQMSRA-SAQVRWFKGSVELQPGAKYEMISDGLYRKLVINAVQPEDEDTYTCDA---- 1571
Query: 216 GEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKD 395
G+V +S V+EQ + + R L+DV P FEC +S W L+
Sbjct: 1572 GDVKTSAQFFVEEQSI--TIVRGLQDVTVMEPAPAWFECELSIPSVRPPKWLLGKTVLQA 1629
Query: 396 GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPL 575
G ++ V L + +T + G T IG + S+A L++++ P PL
Sbjct: 1630 GADVGIEQEGTVHRLTLRRTFSTMTGPVHFT----IGKSRSTASLVVSD--IPTVLTRPL 1683
Query: 576 APVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGD 755
P +S C P V W K+ + G +++ + A L +L++ D
Sbjct: 1684 EPKVGRELQSVVLSCDFK-PPPKAVQWYKEETPLAPSGKFKMRLEGHMAELRVLRLTPAD 1742
Query: 756 TGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS-FRLEGRVAGSQP 932
G Y C A G +A++ ++ R + T+ L + EG++ F E +
Sbjct: 1743 AGVYRCQA----GSAQSSAEVTVEVREV--MVTQPLQDLEVTEEGSACFSCE---LSHED 1793
Query: 933 ISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIV 1112
V W N ++ + EIT + L +K+ D G A S T+S
Sbjct: 1794 EEVEWSLNGTPLYNDSFHEITHEGRRHTLVLKRVRQADRGTVC------ASSPKVTASAH 1847
Query: 1113 IKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFAN 1292
++ KP VF + L ++V E L L C V + W K G E+ PSD+ F
Sbjct: 1848 LEVKGKPVVFLKALDDMSVEEQGTLALQCEV-SDHQAHVVWRKDGVELGPSDKYDFLHTA 1906
Query: 1293 GTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVS 1472
GT L D+++ DAG Y C G+D + ++V+ D +
Sbjct: 1907 GTRGLVVHDLSRDDAGLYTCD----VGTDETHARVSVH--------------DLHVGITK 1948
Query: 1473 EPQSIRVVEKTTATFIAKVGGDPIPNVK-WTKGKWRQLNQGGRIFIHQKGDEAKLEIRDT 1649
+++ V+ + +F + + +V WT G + + R ++G + L +RD
Sbjct: 1949 RLKTVEVLVGESCSFECVLSHENTGDVAVWTVG-GKTVASSDRFQATRQGRKYTLVVRDA 2007
Query: 1650 TKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQ-EKIEGDLRAMLKKTPVLK 1802
+D+G V F+ ++ S +L V ER K D +AML + VL+
Sbjct: 2008 VPSDAGE---VVFSVR-DLTSKASLIVRERLVDIVKPLEDQQAMLGEDVVLR 2055
Score = 129 bits (325), Expect = 5e-30
Identities = 149/595 (25%), Positives = 225/595 (37%), Gaps = 17/595 (2%)
Frame = +3
Query: 30 ASLQCQLAGT---------PEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
A LQ + GT P V+W KG T+LR + + L + ++ DS
Sbjct: 2131 ADLQVEEKGTAVFACKTERPAASVTWCKGLTELRASGKHMPSQEGLTLRLTISALEKADS 2190
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
Y C ++G+ S L VQ QK+ L D + G F C +S ++ V
Sbjct: 2191 DTYTC----NIGQAQSQARLLVQGQKV--FIMEDLEDTEVQEGSSATFCCRISPADYKPV 2244
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
WF D PL N ++ T R A + S T G +SA L +TE
Sbjct: 2245 HWFLDKTPLY--ANELNEIEAQPGGYHVL-TLRQLALKDSGTVHFEAGDQRASAALRVTE 2301
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
P F L V GE C T V W KD + +R + +Y A
Sbjct: 2302 --KPSVFSQELTDVTVTEGEDLTLVCE-TAALDNPVCWTKDGKALRPSARCRQTYEGRRA 2358
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I D+G+Y C E G ++ + + R P + ++ + +E EG +
Sbjct: 2359 QLVITDTTLQDSGRYKC----ETGGAWSSSIVRVHAR---PVWFREGLKDMEILEGGAAT 2411
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
L ++ S + V W + + P + + L L V+ D G Y C +
Sbjct: 2412 LRCMLS-SVAMPVEWRCGDEVLKPGGKYSLRQEGTMLELVVRDLRPQDTGQYCCCFGDQM 2470
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
SA T + P F L EG L C + P+ +W K ++
Sbjct: 2471 TSAKLTVKAL------PAEFIGRLRSKEAKEGVTATLRCELSKEAPV--EWKKGPETLRA 2522
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
R S LE +D+T ADAG+Y C V G + + + +T
Sbjct: 2523 GGRVSLKQEGAVCELEIQDLTVADAGEYSC----VCGQERTSATLTVTALPAE------- 2571
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGD 1622
F+ +S +E TTAT ++ + V+W KG L G R+ + Q G
Sbjct: 2572 -------FIRRLRSKEFMEGTTATLHCELSKEA--PVEWRKGP-ETLRAGDRVSLRQDGV 2621
Query: 1623 EAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE--------RKKQEKIEG 1763
+LEIR D+G Y CV G+ ++ +L V +K+E EG
Sbjct: 2622 MCELEIRGLMVADAGEYSCVC----GQERTSASLTVQALPAKFTKGLRKEEATEG 2672
Score = 127 bits (320), Expect = 2e-29
Identities = 127/452 (28%), Positives = 194/452 (42%), Gaps = 4/452 (0%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVAT--LVFNQVDSNDS 182
+ T G SA+L C+L+ V W KG LR A ++ R + AT L + D+
Sbjct: 3447 EATEGASATLHCELSKAAP--VEWRKGSETLR--AGDRVILRQDGATCELEIRGLTVADA 3502
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
GEY C G+ +S LTV+ LP F R+LR + G C +S P V
Sbjct: 3503 GEYSCVC----GQEKTSAALTVRA--LPAEFIRRLRSKEFMEGTTATLHCELSKEAP--V 3554
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W K L+ G + + L I + AG+YSC G +SA L + +
Sbjct: 3555 EWRKGPETLRAGDRVSLRQDGVMCELEIRGLMVADAGEYSCVC----GQERTSATLTV-Q 3609
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
G++ F PL + A G SA C ++ I V W+K E+++ + + A
Sbjct: 3610 GKDCVFRK-PLQSLQAEEGNSASLRCELSEPSSI-VVWSKGGLELQADRRREPQQRGHIA 3667
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKL-SETVEETEGNSF 899
L + + + D G+YTC G + +A L + P F ++L ++ V+E
Sbjct: 3668 ELVLRDLRREDAGEYTCTC----GSQATSATLTVTAA--PVRFLQELQAQEVDEGATAHL 3721
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
R E AG+ SV W K ++++ P A ++ + L V A DAG YTC D
Sbjct: 3722 RCELSRAGA---SVEWRKGSLQLFPCAKYQMVLEGTTAELLVHGAEQEDAGHYTC----D 3774
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSE-PIRIQWLKAGREI 1256
G T+S+ ++ + PVF L G +L C + SE + WLK G E+
Sbjct: 3775 TGHMQSTASLSVRALQ--PVFKTELQNAEQEAGGVARLCCQLNNSELGAPVLWLKEGVEL 3832
Query: 1257 KPSDRCSFSFANGTAVLEFKDVTKADAGDYVC 1352
+ S + T L + D G+Y C
Sbjct: 3833 QVSSKYEMRRKGATCELLIHGLEAKDTGEYTC 3864
Score = 120 bits (300), Expect = 4e-27
Identities = 148/587 (25%), Positives = 240/587 (40%), Gaps = 7/587 (1%)
Frame = +3
Query: 3 PVKVTVG---DSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDS 173
P++ VG S L C P+ V WYK +T L P+ +KM ++A L ++
Sbjct: 1682 PLEPKVGRELQSVVLSCDFKPPPK-AVQWYKEETPLAPSGKFKMRLEGHMAELRVLRLTP 1740
Query: 174 NDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEP 353
D+G Y C+A G SS +TV+ +++ ++ L+D++ T F C +S E
Sbjct: 1741 ADAGVYRCQA----GSAQSSAEVTVEVREV--MVTQPLQDLEVTEEGSACFSCELS-HED 1793
Query: 354 ISVSWFKDGRPLKDGPNIQTSFLDNVATL---NIFQTDRSFAGQYSCTATNPIGSASSSA 524
V W +G PL + + + TL + Q DR + A++P +AS+
Sbjct: 1794 EEVEWSLNGTPLYNDSFHEITHEGRRHTLVLKRVRQADRG-----TVCASSPKVTASAHL 1848
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
+ +G+ P F L + + +C V+ Q V W KD E+ Y
Sbjct: 1849 EV---KGK-PVVFLKALDDMSVEEQGTLALQCEVSDHQ-AHVVWRKDGVELGPSDKYDFL 1903
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
+ + L + + + D G YTC +VG D A++++ + + TK+L +TVE
Sbjct: 1904 HTAGTRGLVVHDLSRDDAGLYTC----DVGTDETHARVSVHD--LHVGITKRL-KTVEVL 1956
Query: 885 EGNSFRLEGRVAGSQPISVA-WYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYT 1061
G S E ++ VA W + + + T + L V+ A DAG
Sbjct: 1957 VGESCSFECVLSHENTGDVAVWTVGGKTVASSDRFQATRQGRKYTLVVRDAVPSDAGEVV 2016
Query: 1062 CKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLK 1241
V + A S++++E V + L GE + L C + E I + WLK
Sbjct: 2017 FSVRDLTSKA----SLIVRERLVDIV--KPLEDQQAMLGEDVVLRCEL-SREGIPVHWLK 2069
Query: 1242 AGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXX 1421
G+ I+ S + A+L + D G+Y C+ +++SKS +
Sbjct: 2070 DGKAIRKSKKYEVLTEGTWAMLVVHAASLKDCGEYTCE------TESSKSTASLHLEEKP 2123
Query: 1422 XXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRI 1601
F E ++V EK TA F K P +V W KG +L G+
Sbjct: 2124 NR------------FTEELADLQVEEKGTAVFACKT-ERPAASVTWCKG-LTELRASGKH 2169
Query: 1602 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
Q+G +L I K DS Y C G+ +S L V +K
Sbjct: 2170 MPSQEGLTLRLTISALEKADSDTYTC----NIGQAQSQARLLVQGQK 2212
Score = 115 bits (287), Expect = 1e-25
Identities = 125/463 (26%), Positives = 195/463 (42%), Gaps = 3/463 (0%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G +A+L C+L+ E V W KG LR + + L + D+GEY C
Sbjct: 3539 GTTATLHCELS--KEAPVEWRKGPETLRAGDRVSLRQDGVMCELEIRGLMVADAGEYSCV 3596
Query: 201 AENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS-VSWFKD 377
G+ +S LTVQ + F + L+ +Q G C +S EP S V W K
Sbjct: 3597 C----GQERTSATLTVQGKDCV--FRKPLQSLQAEEGNSASLRCELS--EPSSIVVWSKG 3648
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
G L+ + ++A L + R AG+Y+CT GS ++SA L +T P
Sbjct: 3649 GLELQADRRREPQQRGHIAELVLRDLRREDAGEYTCTC----GSQATSATLTVTAA--PV 3702
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F L + G +A C ++ V W K + ++ YQ+ +A L +
Sbjct: 3703 RFLQELQAQEVDEGATAHLRCELSRAGA-SVEWRKGSLQLFPCAKYQMVLEGTTAELLVH 3761
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
++ D G YTC + G TA L++ R + P F +L + E+ G RL ++
Sbjct: 3762 GAEQEDAGHYTC----DTGHMQSTASLSV--RALQPVFKTEL-QNAEQEAGGVARLCCQL 3814
Query: 918 AGSQ-PISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSAL 1094
S+ V W K VE+ ++ E+ K L + D G YTC V GS
Sbjct: 3815 NNSELGAPVLWLKEGVELQVSSKYEMRRKGATCELLIHGLEAKDTGEYTCMV----GSQK 3870
Query: 1095 CTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRC 1274
+S+ +KEP V + L V E + SC V + + ++W G ++ ++
Sbjct: 3871 TLASLKVKEPDVTIV--RGLVDTEVQADEEAEFSCEVSRAGAMDVEWRLQGLPLQTNEVT 3928
Query: 1275 SFSFANGTA-VLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
+ G L+ K VT DAG S G TS +++T
Sbjct: 3929 EVAVQGGCIHTLKLKSVTPEDAG----TVSFHVGLHTSTAQLT 3967
Score = 114 bits (285), Expect = 2e-25
Identities = 130/564 (23%), Positives = 214/564 (37%), Gaps = 10/564 (1%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+ G SA+L C +A + V+WYK KL + ++ + LV Q D+G
Sbjct: 658 VQAVTGASATLTCDVAQA-QTEVTWYKDGKKLTSGSKVRVEAKGCTRRLVVQQAGKADAG 716
Query: 186 EYICRAENSVGEVSSSTFLTVQEQ-----KLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
EY C A G S L V E K P+ S +VQ G C V+ ++
Sbjct: 717 EYSCEA----GGQKVSFHLDVTEPMEVFAKEQPACS----EVQAMAGASATLSCEVAQAQ 768
Query: 351 PISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
V+W+KDG+ L + L + Q ++ AG+Y+C A G S L
Sbjct: 769 T-EVTWYKDGKKLTSSSKVHVEAKGCTRRLMVHQAGKADAGEYTCKA----GGQKVSFHL 823
Query: 531 ILTEGRNPPFF-----DIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNY 695
+TE P + V A G S C V Q +V W KD +++ +
Sbjct: 824 DVTE----PMVVFAKEQLMRREVQAKAGASTTLSCEVAQAQT-EVTWYKDGKKLSASSKV 878
Query: 696 QISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETV 875
+ + L + +V K D G+Y+C A + K S + E + + E +
Sbjct: 879 HVEAKGCTRRLVVQQVGKADAGEYSCEAGGQ--KVSFHLDVTEPEPELAALERPRRREPL 936
Query: 876 EETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGL 1055
E L +A +V W K+ VEI + E+ L V A D+ +
Sbjct: 937 VVKEHEDIVLTATLATPSVAAVTWLKDGVEIRRSKRHEMASLGETHTLTVHGAQTLDSAV 996
Query: 1056 YTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQW 1235
Y+C+V + ++ + F + L V+ G + L+C + ++ + W
Sbjct: 997 YSCRVGAEG------QDFPVQVEEVAAKFCRPLESVSGELGGTVTLTCELSPAQAEAV-W 1049
Query: 1236 LKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXX 1415
+++ R + A L + DAG+YVC++ + D + + +T
Sbjct: 1050 RCGNTQLRAGKRFQMAAAGLQRSLTVTGLRAEDAGEYVCQSRD----DRTSATLT----- 1100
Query: 1416 XXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGG 1595
V + F S ++ E A F V + + G QL++
Sbjct: 1101 --------VRVPRMVKFTSPLSAVVAEEGCEANFQCVVTPSDVAVTWFRDGLQLQLSE-- 1150
Query: 1596 RIFIHQKGDEAKLEIRDTTKTDSG 1667
+ I Q+G L I DSG
Sbjct: 1151 KFLISQRGASHSLTISSLALEDSG 1174
Score = 100 bits (248), Expect = 4e-21
Identities = 110/456 (24%), Positives = 177/456 (38%), Gaps = 1/456 (0%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
P+ V + L LA V+W K ++R + ++M TL + + DS
Sbjct: 935 PLVVKEHEDIVLTATLATPSVAAVTWLKDGVEIRRSKRHEMASLGETHTLTVHGAQTLDS 994
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
Y CR VG VQ +++ F R L V +G V C +S ++ +V
Sbjct: 995 AVYSCR----VGAEGQD--FPVQVEEVAAKFCRPLESVSGELGGTVTLTCELSPAQAEAV 1048
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W L+ G Q + +L + AG+Y C + + SA+ + R+
Sbjct: 1049 -WRCGNTQLRAGKRFQMAAAGLQRSLTVTGLRAEDAGEYVCQSRDDRTSATLTVRV---- 1103
Query: 543 GRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSA 722
F PL+ V A G A+F+C VT + + V W +D +++ + IS S
Sbjct: 1104 -PRMVKFTSPLSAVVAEEGCEANFQCVVTPSD-VAVTWFRDGLQLQLSEKFLISQRGASH 1161
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLS-ETVEETEGNSF 899
LTI + D+GQ T A TA L ++E P F KKL +TVEE +
Sbjct: 1162 SLTISSLALEDSGQITAEAEGV----KSTAALRVREA--PVLFKKKLEPQTVEERSSVTM 1215
Query: 900 RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSND 1079
+E Q V W +N + P N EI + + L + D G Y C+ +D
Sbjct: 1216 AVE---LTRQWPEVKWTRNAAALVPGENVEIHAEGESHRLVLHSVGFADRGFYGCETPDD 1272
Query: 1080 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK 1259
A T + + + L V E + + ++ + W + G ++
Sbjct: 1273 KTQAKLTVEM------RQVRLVRGLQAVEAQEQGVATMEVELSHAD-VEGSWTRDGLRLQ 1325
Query: 1260 PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNV 1367
P C + T L + + D G +A V
Sbjct: 1326 PGPTCQLAVHGPTHSLTLSQLQRQDGGLVTFRAEGV 1361
Score = 97.1 bits (240), Expect = 3e-20
Identities = 139/596 (23%), Positives = 233/596 (39%), Gaps = 22/596 (3%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
+G + +L C+L+ V W G+T+LR ++M +L + + D+GEY+C
Sbjct: 1030 LGGTVTLTCELSPAQAEAV-WRCGNTQLRAGKRFQMAAAGLQRSLTVTGLRAEDAGEYVC 1088
Query: 198 RAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKD 377
++ + +S LTV+ ++ F+ L V G F+C V+ S+ ++V+WF+D
Sbjct: 1089 QSRDD----RTSATLTVRVPRMV-KFTSPLSAVVAEEGCEANFQCVVTPSD-VAVTWFRD 1142
Query: 378 GRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPP 557
G L+ + FL + + T S A + S T S+A L + E P
Sbjct: 1143 GLQLQ----LSEKFLISQRGASHSLTISSLALEDSGQITAEAEGVKSTAALRVREA--PV 1196
Query: 558 FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTIL 737
F L P S +T P +V W ++ + G N +I S L +
Sbjct: 1197 LFKKKLEPQTVEERSSVTMAVELTRQWP-EVKWTRNAAALVPGENVEIHAEGESHRLVLH 1255
Query: 738 KVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRV 917
V D G Y C E D A+L ++ R + + L + VE E +E +
Sbjct: 1256 SVGFADRGFYGC----ETPDDKTQAKLTVEMRQV--RLVRGL-QAVEAQEQGVATMEVEL 1308
Query: 918 AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALC 1097
+ + + +W ++ + + P C++ L + + D GL T + SA
Sbjct: 1309 SHAD-VEGSWTRDGLRLQPGPTCQLAVHGPTHSLTLSQLQRQDGGLVTFRAEGVHTSA-- 1365
Query: 1098 TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEP-IRIQWLKAGREIKPSDRC 1274
+V+ E P F + L V +E + + L C + S P + ++WLK G E++ S
Sbjct: 1366 --QLVVTE--LPVKFSRPLQDVVATEKDKVILDCEL--SRPNVDVRWLKDGVELRLSKTV 1419
Query: 1275 SFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDG 1454
L D G Y+C A + + TS S G
Sbjct: 1420 GMVAQGSCRSLIIYRCELGDQGVYMCDAHD---AQTSASLKVQGRTYTLIYRRVLVGDAG 1476
Query: 1455 KLFFVSE----PQSIRVVEKTTATFIAKVGGDPI-----------------PNVKWTKGK 1571
++ FV+E +RV E A I + D I V+W KG
Sbjct: 1477 EIKFVAENAESRAQLRVKELPVA--ILRPLRDKIAMEKHRGVLECQMSRASAQVRWFKGS 1534
Query: 1572 WRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
+L G + + G KL I D Y C A G+++++ V E+
Sbjct: 1535 -VELQPGAKYEMISDGLYRKLVINAVQPEDEDTYTCDA----GDVKTSAQFFVEEQ 1585
Score = 94.4 bits (233), Expect = 2e-19
Identities = 119/546 (21%), Positives = 202/546 (36%), Gaps = 94/546 (17%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKM-HFRNNVATLVFNQVDSNDSGEYI 194
VGD L+C ++ ++ W K +L + + + +L+ + D+G Y
Sbjct: 4621 VGDVLHLECVVSSKTDVRAHWLKDGVELTDGRHHHIDQLGDGTCSLLVTSLGQADAGRYT 4680
Query: 195 CRAENSVGEVSSSTFLTVQEQK----------LPPSFSRQLRDVQET--------VGLPV 320
C+ N G V+ S + V + L +F R R + V
Sbjct: 4681 CQVSNKFGRVAHSACVVVSGTESETESSSGGELDDTFRRAARRLHRLFRTKGPAEVSDEE 4740
Query: 321 VFECAVSGSEPISV-----SWFKDGR-------PLKDGPNIQTSFLDNVATLNIFQTDRS 464
+F A G E ++ +D L + T F + T+ I D S
Sbjct: 4741 LFFSADEGKEEPEEPGDWQTYHEDEHFVCIRFETLVEARRAVTCFREMFGTMGI-GVDIS 4799
Query: 465 FAGQYSCTATNPIGSASSSA-----RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVT 629
+ Q IG + ++ ++ TE P F L + + G F+C VT
Sbjct: 4800 LSEQGPRGVEMRIGKVAPTSVAPPEPVLTTEAA--PVFLTELQNQEVLDGYPVSFDCVVT 4857
Query: 630 GTQPIKVAWAKDNREIRSGGNYQISYLENSAH-LTILKVDKGDTGQYTCYAVNEVGKDSC 806
G V W KD R + +Y IS + H L I V D G Y C A N VG S
Sbjct: 4858 GQPVPSVRWFKDGRVLEEDDHYMISEDQQGGHQLIITAVVPADMGVYRCLAENSVGVSST 4917
Query: 807 TAQLNI------------------------------KERLIPPSFTKKLSETVEETE--- 887
A+L + +E S +L + V+E +
Sbjct: 4918 KAELRVDLTSTDYETAADATETSSYFSAQGYLSSREQEGTESTSEEGQLPQVVQELKDLQ 4977
Query: 888 ---GNSF-RLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGL 1055
G S + + +V G + W+K+ + + + + + L++ + DAG
Sbjct: 4978 VAPGTSLAKFQVKVKGYPTPRLYWFKDGQPLTASEHIRMADRKTLHTLEIVSVTSKDAGQ 5037
Query: 1056 YTCKVSNDAGSALCTSSIVIKEPKK--------------PPVFDQHLTPVTVSEGEFLQL 1193
Y+ +SN G+A ++ +++++P K PP F + T V +G +
Sbjct: 5038 YSAYISNTVGAAYSSARLLVRDPGKPEEKPTSDIHQQLVPPRFLEKFTFKKVKKGSSITF 5097
Query: 1194 SCHVRGSEPIRIQWLK--AGREIKPSDRCSFSFANGTAV----LEFKDVTKADAGDYVCK 1355
S V G+ P + WL+ A + + DR + + ++ L DV + G Y C
Sbjct: 5098 SVKVEGNPPPAVHWLREEAEQGVLWIDRHTPGYTVASSAQQHSLVLLDVGRQHQGTYTCI 5157
Query: 1356 ASNVAG 1373
A+N AG
Sbjct: 5158 ATNAAG 5163
Score = 94.4 bits (233), Expect = 2e-19
Identities = 89/331 (26%), Positives = 125/331 (37%), Gaps = 59/331 (17%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKM-HFRNNVATLVFNQVDSNDSG 185
+V G S C + G P V W+K L Y + + L+ V D G
Sbjct: 4843 EVLDGYPVSFDCVVTGQPVPSVRWFKDGRVLEEDDHYMISEDQQGGHQLIITAVVPADMG 4902
Query: 186 EYICRAENSVGEVSSSTFLTVQ-------------------------------------E 254
Y C AENSVG S+ L V E
Sbjct: 4903 VYRCLAENSVGVSSTKAELRVDLTSTDYETAADATETSSYFSAQGYLSSREQEGTESTSE 4962
Query: 255 QKLPPSFSRQLRDVQETVGLPVV-FECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNV 431
+ P ++L+D+Q G + F+ V G + WFKDG+PL +I+ + +
Sbjct: 4963 EGQLPQVVQELKDLQVAPGTSLAKFQVKVKGYPTPRLYWFKDGQPLTASEHIRMADRKTL 5022
Query: 432 ATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNP---PFFDI--PLAP----- 581
TL I AGQYS +N +G+A SSARL++ + P P DI L P
Sbjct: 5023 HTLEIVSVTSKDAGQYSAYISNTVGAAYSSARLLVRDPGKPEEKPTSDIHQQLVPPRFLE 5082
Query: 582 ----VDAVVGESADFECHVTGTQPIKVAWAKDNRE------IRSGGNYQISYLENSAHLT 731
G S F V G P V W ++ E R Y ++ L
Sbjct: 5083 KFTFKKVKKGSSITFSVKVEGNPPPAVHWLREEAEQGVLWIDRHTPGYTVASSAQQHSLV 5142
Query: 732 ILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI 824
+L V + G YTC A N G+ C+A L++
Sbjct: 5143 LLDVGRQHQGTYTCIATNAAGQALCSAGLHV 5173
Score = 90.5 bits (223), Expect = 3e-18
Identities = 61/189 (32%), Positives = 91/189 (48%), Gaps = 4/189 (2%)
Frame = +3
Query: 264 PPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGP-NIQTSFLDNVATL 440
PP F +L D +G V C V+G+ VSW+KDG+P++ P +I D L
Sbjct: 5722 PPDFEEELADCTAKLGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCAL 5781
Query: 441 NIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFEC 620
+ +GQY C A + G+AS+ ++++ + PP F + V V GE A C
Sbjct: 5782 ILDNLTGIDSGQYMCFAASAAGNASTLGKILV---QVPPRFVKKVRAVPFVEGEDAQITC 5838
Query: 621 HVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVD---KGDTGQYTCYAVNEV 791
+ G ++ W KD + SGG YQI E + L +L++ K D G Y C VN +
Sbjct: 5839 TIEGAPYPRIRWYKDGTLLTSGGKYQI-LSEPRSGLLVLEIQAAGKEDLGLYECELVNWL 5897
Query: 792 GKDSCTAQL 818
G A+L
Sbjct: 5898 GSKRGGAEL 5906
Score = 85.9 bits (211), Expect = 8e-17
Identities = 135/593 (22%), Positives = 220/593 (37%), Gaps = 35/593 (5%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V T D L C+L+ P + V W K +LR + T M + + +L+ + + D G
Sbjct: 1383 VVATEKDKVILDCELS-RPNVDVRWLKDGVELRLSKTVGMVAQGSCRSLIIYRCELGDQG 1441
Query: 186 EYICRAENS---------------------VGEVSSSTFLT--------VQEQKLPPSFS 278
Y+C A ++ VG+ F+ ++ ++LP +
Sbjct: 1442 VYMCDAHDAQTSASLKVQGRTYTLIYRRVLVGDAGEIKFVAENAESRAQLRVKELPVAIL 1501
Query: 279 RQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQ--TSFLDNVATLNIFQ 452
R LRD V EC +S + V WFK L+ G + + L +N Q
Sbjct: 1502 RPLRDKIAMEKHRGVLECQMSRAS-AQVRWFKGSVELQPGAKYEMISDGLYRKLVINAVQ 1560
Query: 453 TDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESAD--FECHV 626
+ Y+C A G +SA+ + E I D V E A FEC +
Sbjct: 1561 PEDE--DTYTCDA----GDVKTSAQFFVEE----QSITIVRGLQDVTVMEPAPAWFECEL 1610
Query: 627 TGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSC 806
+ W +++G + I LT+ + TG +GK
Sbjct: 1611 SIPSVRPPKWLLGKTVLQAGADVGIEQEGTVHRLTLRRTFSTMTGPVHF----TIGKSRS 1666
Query: 807 TAQLNIKERLIPPSFTKKLSETV-EETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTAN 983
TA L + + IP T+ L V E + + + P +V WYK + P+
Sbjct: 1667 TASLVVSD--IPTVLTRPLEPKVGRELQSVVLSCDFK---PPPKAVQWYKEETPLAPSGK 1721
Query: 984 CEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPV 1163
++ + + L+V + + DAG+Y C+ AGSA ++ + ++ + + Q L +
Sbjct: 1722 FKMRLEGHMAELRVLRLTPADAGVYRCQ----AGSAQSSAEVTVE--VREVMVTQPLQDL 1775
Query: 1164 TVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGD 1343
V+E SC + E ++W G + + L K V +AD G
Sbjct: 1776 EVTEEGSACFSCEL-SHEDEEVEWSLNGTPLYNDSFHEITHEGRRHTLVLKRVRQADRGT 1834
Query: 1344 YVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGK-LFFVSEPQSIRVVEKTTATFI 1520
VC S KVT V GK + F+ + V E+ T
Sbjct: 1835 -VC---------ASSPKVT---------ASAHLEVKGKPVVFLKALDDMSVEEQGTLALQ 1875
Query: 1521 AKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRC 1679
+V D +V W K F+H G L + D ++ D+GLY C
Sbjct: 1876 CEV-SDHQAHVVWRKDGVELGPSDKYDFLHTAGTRG-LVVHDLSRDDAGLYTC 1926
Score = 85.9 bits (211), Expect = 8e-17
Identities = 83/344 (24%), Positives = 136/344 (39%), Gaps = 63/344 (18%)
Frame = +3
Query: 267 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVA-TLN 443
P F +L++ + G PV F+C V+G SV WFKDGR L++ + S L
Sbjct: 4833 PVFLTELQNQEVLDGYPVSFDCVVTGQPVPSVRWFKDGRVLEEDDHYMISEDQQGGHQLI 4892
Query: 444 IFQTDRSFAGQYSCTATNPIGSASSSARLILT---------------------------- 539
I + G Y C A N +G +S+ A L +
Sbjct: 4893 ITAVVPADMGVYRCLAENSVGVSSTKAELRVDLTSTDYETAADATETSSYFSAQGYLSSR 4952
Query: 540 ----------EGRNPPFF----DIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI 677
EG+ P D+ +AP ++ A F+ V G ++ W KD + +
Sbjct: 4953 EQEGTESTSEEGQLPQVVQELKDLQVAPGTSL----AKFQVKVKGYPTPRLYWFKDGQPL 5008
Query: 678 RSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQL------------- 818
+ + +++ + L I+ V D GQY+ Y N VG +A+L
Sbjct: 5009 TASEHIRMADRKTLHTLEIVSVTSKDAGQYSAYISNTVGAAYSSARLLVRDPGKPEEKPT 5068
Query: 819 -NIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEI------HPT 977
+I ++L+PP F +K + + +G+S +V G+ P +V W + E T
Sbjct: 5069 SDIHQQLVPPRFLEKFTFK-KVKKGSSITFSVKVEGNPPPAVHWLREEAEQGVLWIDRHT 5127
Query: 978 ANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSI 1109
+ L + G YTC +N AG ALC++ +
Sbjct: 5128 PGYTVASSAQQHSLVLLDVGRQHQGTYTCIATNAAGQALCSAGL 5171
Score = 80.9 bits (198), Expect = 2e-15
Identities = 53/194 (27%), Positives = 93/194 (47%), Gaps = 3/194 (1%)
Frame = +3
Query: 552 PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNY-QISYLENSAHL 728
PP F+ LA A +GE+ C VTGT V+W KD + + ++ I + S L
Sbjct: 5722 PPDFEEELADCTAKLGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCAL 5781
Query: 729 TILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLE 908
+ + D+GQY C+A + G S ++ ++ +PP F KK+ V EG ++
Sbjct: 5782 ILDNLTGIDSGQYMCFAASAAGNASTLGKILVQ---VPPRFVKKV-RAVPFVEGEDAQIT 5837
Query: 909 GRVAGSQPISVAWYKNNVEIHPTANCEITF--KNNALLLQVKKASMGDAGLYTCKVSNDA 1082
+ G+ + WYK+ + +I ++ L+L+++ A D GLY C++ N
Sbjct: 5838 CTIEGAPYPRIRWYKDGTLLTSGGKYQILSEPRSGLLVLEIQAAGKEDLGLYECELVNWL 5897
Query: 1083 GSALCTSSIVIKEP 1124
GS + + ++ P
Sbjct: 5898 GSKRGGAELFMQSP 5911
Score = 75.5 bits (184), Expect = 1e-13
Identities = 72/277 (25%), Positives = 117/277 (42%), Gaps = 4/277 (1%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+V G +A L+C+L+ V W KG +L P A Y+M A L+ + + D+G
Sbjct: 3712 EVDEGATAHLRCELSRAGA-SVEWRKGSLQLFPCAKYQMVLEGTTAELLVHGAEQEDAGH 3770
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE-PISVS 365
Y C G + S+ L+V + L P F +L++ ++ G C ++ SE V
Sbjct: 3771 YTC----DTGHMQSTASLSV--RALQPVFKTELQNAEQEAGGVARLCCQLNNSELGAPVL 3824
Query: 366 WFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
W K+G L+ + L I + G+Y+C +GS + A L + E
Sbjct: 3825 WLKEGVELQVSSKYEMRRKGATCELLIHGLEAKDTGEYTCM----VGSQKTLASLKVKE- 3879
Query: 546 RNPPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENS 719
P I VD V E A+F C V+ + V W +++ +++
Sbjct: 3880 ---PDVTIVRGLVDTEVQADEEAEFSCEVSRAGAMDVEWRLQGLPLQTNEVTEVAVQGGC 3936
Query: 720 AHLTILK-VDKGDTGQYTCYAVNEVGKDSCTAQLNIK 827
H LK V D G + + VG + TAQL ++
Sbjct: 3937 IHTLKLKSVTPEDAGTVSFH----VGLHTSTAQLTVR 3969
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/179 (27%), Positives = 79/179 (44%), Gaps = 6/179 (3%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFR----NNVATLVFNQVDSNDSG 185
+G++ L C++ GTP+ VSWYK +P H + L+ + + DSG
Sbjct: 5736 LGETVKLACRVTGTPKPIVSWYKDG---KPVEVDPHHILIEDPDGSCALILDNLTGIDSG 5792
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVS 365
+Y+C A ++ G S+ + VQ +PP F +++R V G C + G+ +
Sbjct: 5793 QYMCFAASAAGNASTLGKILVQ---VPPRFVKKVRAVPFVEGEDAQITCTIEGAPYPRIR 5849
Query: 366 WFKDGRPLKDGPNIQ--TSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
W+KDG L G Q + + L I + G Y C N +GS A L +
Sbjct: 5850 WYKDGTLLTSGGKYQILSEPRSGLLVLEIQAAGKEDLGLYECELVNWLGSKRGGAELFM 5908
Score = 73.2 bits (178), Expect = 5e-13
Identities = 63/244 (25%), Positives = 106/244 (43%), Gaps = 10/244 (4%)
Frame = +3
Query: 1128 KPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIK-PSDRCSFSFANGTAV 1304
+PP F++ L T GE ++L+C V G+ + W K G+ ++ +G+
Sbjct: 5721 RPPDFEEELADCTAKLGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCA 5780
Query: 1305 LEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQS 1484
L ++T D+G Y+C A++ AG+ ++ K+ V FV + ++
Sbjct: 5781 LILDNLTGIDSGQYMCFAASAAGNASTLGKI---------------LVQVPPRFVKKVRA 5825
Query: 1485 IRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGR--IFIHQKGDEAKLEIRDTTKT 1658
+ VE A + G P P ++W K L GG+ I + LEI+ K
Sbjct: 5826 VPFVEGEDAQITCTIEGAPYPRIRWYK-DGTLLTSGGKYQILSEPRSGLLVLEIQAAGKE 5884
Query: 1659 DSGLYRCVAFN----KHGEIE---SNVNLQVNERKKQEKIEGDLRAMLKKTPVLKKGAGE 1817
D GLY C N K G E + LQ ++ ++E++ + ++T V KK
Sbjct: 5885 DLGLYECELVNWLGSKRGGAELFMQSPALQARQQHRKEQLAA-VEVTEQETKVPKKTIII 5943
Query: 1818 EEEI 1829
EE I
Sbjct: 5944 EETI 5947
Score = 68.9 bits (167), Expect = 1e-11
Identities = 53/183 (28%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
Frame = +3
Query: 840 PPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNN--VEIHPTANCEITFKNNAL 1013
PP F ++L++ + G + +L RV G+ V+WYK+ VE+ P + I + +
Sbjct: 5722 PPDFEEELADCTAKL-GETVKLACRVTGTPKPIVSWYKDGKPVEVDPH-HILIEDPDGSC 5779
Query: 1014 LLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQL 1193
L + + D+G Y C ++ AG+A I++ + PP F + + V EGE Q+
Sbjct: 5780 ALILDNLTGIDSGQYMCFAASAAGNASTLGKILV---QVPPRFVKKVRAVPFVEGEDAQI 5836
Query: 1194 SCHVRGSEPIRIQWLKAGREIKPSDRCSF--SFANGTAVLEFKDVTKADAGDYVCKASNV 1367
+C + G+ RI+W K G + + +G VLE + K D G Y C+ N
Sbjct: 5837 TCTIEGAPYPRIRWYKDGTLLTSGGKYQILSEPRSGLLVLEIQAAGKEDLGLYECELVNW 5896
Query: 1368 AGS 1376
GS
Sbjct: 5897 LGS 5899
Score = 62.4 bits (150), Expect = 9e-10
Identities = 51/196 (26%), Positives = 78/196 (39%), Gaps = 21/196 (10%)
Frame = +3
Query: 6 VKVTVGDS-ASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
++V G S A Q ++ G P + W+K L + +M R + TL V S D+
Sbjct: 4976 LQVAPGTSLAKFQVKVKGYPTPRLYWFKDGQPLTASEHIRMADRKTLHTLEIVSVTSKDA 5035
Query: 183 GEYICRAENSVGEVSSSTFLTVQ--------------EQKLPPSFSRQLRDVQETVGLPV 320
G+Y N+VG SS L V+ +Q +PP F + + G +
Sbjct: 5036 GQYSAYISNTVGAAYSSARLLVRDPGKPEEKPTSDIHQQLVPPRFLEKFTFKKVKKGSSI 5095
Query: 321 VFECAVSGSEPISVSWFKDGRPL------KDGPNIQTSFLDNVATLNIFQTDRSFAGQYS 482
F V G+ P +V W ++ + P + +L + R G Y+
Sbjct: 5096 TFSVKVEGNPPPAVHWLREEAEQGVLWIDRHTPGYTVASSAQQHSLVLLDVGRQHQGTYT 5155
Query: 483 CTATNPIGSASSSARL 530
C ATN G A SA L
Sbjct: 5156 CIATNAAGQALCSAGL 5171
Score = 57.8 bits (138), Expect = 2e-08
Identities = 88/394 (22%), Positives = 155/394 (39%), Gaps = 21/394 (5%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKM-HFRNNVA-TLVFNQVDSND 179
V+ G A +C L+ +W D + + ++ +F N + L+ + D
Sbjct: 4069 VEAPEGGEALFECLLSRPEVAAHTWLLDDEPVHTSENAEVVYFENGLRHLLLLKNLRPQD 4128
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
S CR G++ +S FLTV+ +L + Q DV G F C +S + P+
Sbjct: 4129 S----CRVTFLAGDMVTSAFLTVRGWRLEVLEAPQ--DVAVRAGGQASFSCMLSEAVPVG 4182
Query: 360 -VSWFKDGRPLKDGPNIQTSFLDNVA-TLNIFQTDRSFAGQYSCTATNPIGSASSSARLI 533
+W+ +G ++ T D L + Q AG+ + A + + +SARL
Sbjct: 4183 EATWYINGAVVQPDDRDWTVTADGSQHALLLHQAQPHHAGEVTFAARDAV----ASARLT 4238
Query: 534 LTEGRNPPFFDIPLAPVDA-VVGESADFECHVTGTQPIKVAW---AKDNR--------EI 677
+ +P P DA VVG S+ + ++W A D E+
Sbjct: 4239 V--------LGLPDPPEDAEVVGRSSS---------SVTLSWVAPASDGGGGLCGYRVEM 4281
Query: 678 RSG--GNYQISY-LENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCT--AQLNIKERLIP 842
+S G +++ + L + + G+T ++ AV+ G Q ++ +P
Sbjct: 4282 KSAATGEWRLCHELVPGPECVVDGLAPGETYRFRVAAVSPAGSGEPVYLPQTPLEPMTVP 4341
Query: 843 PSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQ 1022
P+ +T + G LE VA + V W K I P+ ++ + +L
Sbjct: 4342 PA-----PKTRQVAAGEDLCLECEVAEAG--EVVWLKGTERIQPSGRVQVLCQGQRQMLL 4394
Query: 1023 VKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEP 1124
++ S D G Y C + D+ S TS V+ P
Sbjct: 4395 IRGFSPEDQGEYCCSPARDSASVAATSFQVVLTP 4428
Score = 54.3 bits (129), Expect = 2e-07
Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Frame = +3
Query: 267 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQ-TSFLDNVATLN 443
PSF R+L D +G V C VS +W KDG PL+ + +S L N L
Sbjct: 7587 PSFLRELSDEMVVLGQSVTLACQVSAQPAAQATWSKDGTPLESSSRLLISSTLKNFQLLT 7646
Query: 444 IFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNP 554
+ G Y+C+ +N +G+A+++A IL + P
Sbjct: 7647 LLVVTAEDLGVYTCSVSNALGTATTTA--ILQKAERP 7681
Score = 53.1 bits (126), Expect = 5e-07
Identities = 50/215 (23%), Positives = 84/215 (39%), Gaps = 10/215 (4%)
Frame = +3
Query: 1134 PVFDQHLTPVTVSEGEFL-QLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLE 1310
P Q L + V+ G L + V+G R+ W K G+ + S+ + LE
Sbjct: 4967 PQVVQELKDLQVAPGTSLAKFQVKVKGYPTPRLYWFKDGQPLTASEHIRMADRKTLHTLE 5026
Query: 1311 FKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLF---FVSEPQ 1481
VT DAG Y SN G+ S +++ + +L F+ +
Sbjct: 5027 IVSVTSKDAGQYSAYISNTVGAAYSSARL-LVRDPGKPEEKPTSDIHQQLVPPRFLEKFT 5085
Query: 1482 SIRVVEKTTATFIAKVGGDPIPNVKWTKGK------WRQLNQGGRIFIHQKGDEAKLEIR 1643
+V + ++ TF KV G+P P V W + + W + G + + L +
Sbjct: 5086 FKKVKKGSSITFSVKVEGNPPPAVHWLREEAEQGVLWIDRHTPG-YTVASSAQQHSLVLL 5144
Query: 1644 DTTKTDSGLYRCVAFNKHGEIESNVNLQVNERKKQ 1748
D + G Y C+A N G+ + L V+ K+
Sbjct: 5145 DVGRQHQGTYTCIATNAAGQALCSAGLHVSGLPKE 5179
Score = 52.8 bits (125), Expect = 7e-07
Identities = 29/94 (30%), Positives = 43/94 (45%)
Frame = +3
Query: 264 PPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLN 443
PPS + DVQ G F+ + G+ +V+W+KDG L DGP + +L
Sbjct: 6482 PPSMQVTIEDVQAQRGGMAQFQAVIEGNPQPTVTWYKDGTQLVDGPQLSQQQEGTTYSLV 6541
Query: 444 IFQTDRSFAGQYSCTATNPIGSASSSARLILTEG 545
+ + AG Y+C A N G A L++ G
Sbjct: 6542 LRDVAQRDAGVYTCLAQNAGGQVLCKAELLVHGG 6575
Score = 50.1 bits (118), Expect = 5e-06
Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Frame = +3
Query: 252 EQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFL-DN 428
+Q+ P F R D VG + EC VS + W KDG L DG + L D
Sbjct: 4603 QQQEGPVFCRTFGDTVAQVGDVLHLECVVSSKTDVRAHWLKDGVELTDGRHHHIDQLGDG 4662
Query: 429 VATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
+L + ++ AG+Y+C +N G + SA ++++
Sbjct: 4663 TCSLLVTSLGQADAGRYTCQVSNKFGRVAHSACVVVS 4699
>ref|XP_003130084.1| PREDICTED: roundabout homolog 3 [Sus scrofa].
Length = 1395
Score = 155 bits (391), Expect = 1e-37
Identities = 134/478 (28%), Positives = 211/478 (44%), Gaps = 21/478 (4%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVAT-------LVFNQVD 170
V+ G+ A+L C+ G P + WYK ++ R + + +V +
Sbjct: 75 VSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGALFFPRIVHGRRA 134
Query: 171 SNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSE 350
D G Y C A N +G +S +++ L F + ++ VG P V EC
Sbjct: 135 RPDEGVYTCVARNYLGAAASRN-ASLEVAVLRDDFRQSPGNLVVAVGEPAVMECVPPRGH 193
Query: 351 PI-SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASS-SA 524
P SVSW KDG LK+ T L + T +S AG Y C A+N G S +A
Sbjct: 194 PEPSVSWKKDGARLKEEEGRITI---RGGKLMMSLTLKSDAGMYVCVASNMAGERESGAA 250
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
+L++ E P F P+ V + DF C V G P +++W K++ E+ +G Y+I
Sbjct: 251 KLVVLE--RPSFLRRPVNQV-VLADAPVDFPCEVQGDPPPRLSWRKEDGELPTG-RYEI- 305
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF-TKKLSETVEE 881
+ L I +V D G YTC A N VG+ ++ L++ +PP T+ + V
Sbjct: 306 --RSDHSLWISRVSAEDEGTYTCVAENSVGRAEASSSLSVH---VPPQLVTQPQDQMVAP 360
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVE--------IHPTANCEITFKNNALLLQVKKAS 1037
E +F+ E + G+ P ++ W K + + PT ++ + L + +
Sbjct: 361 GESVAFQCETK--GNPPPAIFWQKEGSQALLFPSQSLQPTGRFSVSPRGQ---LNITEVQ 415
Query: 1038 MGDAGLYTCKVSNDAGSALCTSSIVIKEPKK---PPVFDQHLTPVTVSEGEFLQLSCHVR 1208
GDAG Y C+ + AGS L + + +K PP+ Q T++ G + L C V
Sbjct: 416 SGDAGYYVCQAVSVAGSILAKALLEVKGASLDGLPPIILQGPANQTLALGSSVWLPCRVT 475
Query: 1209 GSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
G+ +QWLK G+ ++ D ANGT L +V + G Y C A + G T
Sbjct: 476 GNPQPSVQWLKDGQWLQGDDVQLNLMANGT--LYITNVQETHMGFYSCVAKSPTGEAT 531
Score = 122 bits (307), Expect = 6e-28
Identities = 137/500 (27%), Positives = 213/500 (42%), Gaps = 21/500 (4%)
Frame = +3
Query: 267 PSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPL---KDGPNIQTSFLDNVAT 437
P Q D+ + G P C G ++ W+K+G + ++ P L + A
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGAL 123
Query: 438 ----LNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGES 605
+ + R G Y+C A N +G+A+S + F P V AV GE
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNLVVAV-GEP 182
Query: 606 ADFECHVTGTQPI-KVAWAKDNREIRSG-GNYQISYLENSAHLTILKVDKGDTGQYTCYA 779
A EC P V+W KD ++ G I + LT+ K D G Y C A
Sbjct: 183 AVMECVPPRGHPEPSVSWKKDGARLKEEEGRITIRGGKLMMSLTL----KSDAGMYVCVA 238
Query: 780 VNEVG-KDSCTAQLNIKERLIPPSFTKK-LSETVEETEGNSFRLEGRVAGSQPISVAWYK 953
N G ++S A+L + ER PSF ++ +++ V F E V G P ++W K
Sbjct: 239 SNMAGERESGAAKLVVLER---PSFLRRPVNQVVLADAPVDFPCE--VQGDPPPRLSWRK 293
Query: 954 NNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKP 1133
+ E+ PT EI ++ L + + S D G YTC N G A +SS+ + P P
Sbjct: 294 EDGEL-PTGRYEIRSDHS---LWISRVSAEDEGTYTCVAENSVGRAEASSSLSVHVP--P 347
Query: 1134 PVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGRE--------IKPSDRCSFSFA 1289
+ Q + V+ GE + C +G+ P I W K G + ++P+ R S S
Sbjct: 348 QLVTQPQDQM-VAPGESVAFQCETKGNPPPAIFWQKEGSQALLFPSQSLQPTGRFSVS-- 404
Query: 1290 NGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDG-KLFF 1466
L +V DAG YVC+A +VAGS +K+ + +DG
Sbjct: 405 -PRGQLNITEVQSGDAGYYVCQAVSVAGSILAKALL----------EVKGASLDGLPPII 453
Query: 1467 VSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQLNQGGRIFIHQKGDEAKLEIR 1643
+ P + + ++ +V G+P P+V+W K G+W QG + ++ + L I
Sbjct: 454 LQGPANQTLALGSSVWLPCRVTGNPQPSVQWLKDGQWL---QGDDVQLNLMAN-GTLYIT 509
Query: 1644 DTTKTDSGLYRCVAFNKHGE 1703
+ +T G Y CVA + GE
Sbjct: 510 NVQETHMGFYSCVAKSPTGE 529
Score = 79.0 bits (193), Expect = 9e-15
Identities = 111/468 (23%), Positives = 173/468 (36%), Gaps = 30/468 (6%)
Frame = +3
Query: 417 FLDNVATLNIFQTDRSFAGQYSCTATN----PIGSASSSARLILTEGRNPPFFDIPLAPV 584
F D++A +D F S TA N P G S + + E P + P
Sbjct: 15 FADSLAGDISNSSDLFFGFNSSATALNQSLLPPGDPSVNGSRVGPEDAMPRIVE---QPP 71
Query: 585 DAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISY--LENSAHLTILKVDKG 752
D +V GE A C G + W K+ + + ++ L S L ++ G
Sbjct: 72 DLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGALFFPRIVHG 131
Query: 753 -----DTGQYTCYAVNEVGKD-SCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGR 914
D G YTC A N +G S A L + L + ++ GN G
Sbjct: 132 RRARPDEGVYTCVARNYLGAAASRNASLEVAV----------LRDDFRQSPGNLVVAVGE 181
Query: 915 VA--------GSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKV 1070
A G SV+W K+ + IT + L++ + S DAG+Y C
Sbjct: 182 PAVMECVPPRGHPEPSVSWKKDGARLKEEEG-RITIRGGKLMMSLTLKS--DAGMYVCVA 238
Query: 1071 SNDAGSALC-TSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
SN AG + +V+ E +P + + V +++ + C V+G P R+ W K
Sbjct: 239 SNMAGERESGAAKLVVLE--RPSFLRRPVNQVVLADAP-VDFPCEVQGDPPPRLSWRKED 295
Query: 1248 REIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXX 1427
E+ P+ R + L V+ D G Y C A N G + S ++
Sbjct: 296 GEL-PTGRYEIRSDHS---LWISRVSAEDEGTYTCVAENSVGRAEASSSLSVHVPPQ--- 348
Query: 1428 XXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG-------KWRQLN 1586
V++PQ V + F + G+P P + W K + L
Sbjct: 349 ------------LVTQPQDQMVAPGESVAFQCETKGNPPPAIFWQKEGSQALLFPSQSLQ 396
Query: 1587 QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
GR + +G +L I + D+G Y C A + G I + L+V
Sbjct: 397 PTGRFSVSPRG---QLNITEVQSGDAGYYVCQAVSVAGSILAKALLEV 441
Score = 79.0 bits (193), Expect = 9e-15
Identities = 55/184 (29%), Positives = 86/184 (46%), Gaps = 11/184 (5%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTK--------LRPTATYKMHFRNNVATLVFNQV 167
V G+S + QC+ G P + W K ++ L+PT + + R L +V
Sbjct: 358 VAPGESVAFQCETKGNPPPAIFWQKEGSQALLFPSQSLQPTGRFSVSPRGQ---LNITEV 414
Query: 168 DSNDSGEYICRAENSVGEVSSSTFLTVQEQKL---PPSFSRQLRDVQETVGLPVVFECAV 338
S D+G Y+C+A + G + + L V+ L PP + + +G V C V
Sbjct: 415 QSGDAGYYVCQAVSVAGSILAKALLEVKGASLDGLPPIILQGPANQTLALGSSVWLPCRV 474
Query: 339 SGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASS 518
+G+ SV W KDG+ L+ G ++Q + + N TL I + G YSC A +P G A+
Sbjct: 475 TGNPQPSVQWLKDGQWLQ-GDDVQLNLMAN-GTLYITNVQETHMGFYSCVAKSPTGEATW 532
Query: 519 SARL 530
S L
Sbjct: 533 SGWL 536
Score = 63.9 bits (154), Expect = 3e-10
Identities = 74/293 (25%), Positives = 114/293 (38%), Gaps = 9/293 (3%)
Frame = +3
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEI-----HPTANCEITFKNNALL---LQVKKAS 1037
+ G L R G ++ WYKN + P A+ + + AL + + +
Sbjct: 76 SRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAH-RLLLPSGALFFPRIVHGRRA 134
Query: 1038 MGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSC-HVRGS 1214
D G+YTC N G+A ++ + + F Q + V+ GE + C RG
Sbjct: 135 RPDEGVYTCVARNYLGAAASRNASLEVAVLRDD-FRQSPGNLVVAVGEPAVMECVPPRGH 193
Query: 1215 EPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSK 1394
+ W K G +K + + G ++ K+DAG YVC ASN+AG S +
Sbjct: 194 PEPSVSWKKDGARLKEEEG-RITIRGGKLMMSL--TLKSDAGMYVCVASNMAGERESGAA 250
Query: 1395 VTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKW 1574
V + F+ P + V+ F +V GDP P + W K
Sbjct: 251 --------------KLVVLERPSFLRRPVNQVVLADAPVDFPCEVQGDPPPRLSWRKEDG 296
Query: 1575 RQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVN 1733
GR I + L I + D G Y CVA N G E++ +L V+
Sbjct: 297 ELPT--GRYEIRS---DHSLWISRVSAEDEGTYTCVAENSVGRAEASSSLSVH 344
>ref|XP_003129943.2| PREDICTED: Down syndrome cell adhesion molecule-like protein 1,
partial [Sus scrofa].
Length = 1882
Score = 147 bits (371), Expect = 2e-35
Identities = 145/577 (25%), Positives = 223/577 (38%), Gaps = 13/577 (2%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+V G + L C +G P + W K L + + + L + + + DSG
Sbjct: 65 EVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWT----KRITGLTISDLRTEDSGT 120
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSW 368
YIC N+ G ++ LTV + P + + ++ +G V+ C + GS ++ W
Sbjct: 121 YICEVTNTFGSAEATGTLTVID---PLHVTLTPKKLKTGIGSTVILSCTLMGSPEFTIRW 177
Query: 369 FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+++ + G I L N TL I +S +G Y C A+ +A A ++L +G
Sbjct: 178 YRNTELVLPGEAISIRGLSN-ETLLITSAQKSHSGAYQCFASRKAQTAQDFAIIVLEDG- 235
Query: 549 NPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN-----YQISYLE 713
P + GE C G P V WA D+ I G+ Y +S
Sbjct: 236 -TPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRSNQYTMSDGT 294
Query: 714 NSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGN 893
+H+ + D G Y C A N VG A++N++ PPS + + G
Sbjct: 295 TISHMNVTGPQIRDGGVYRCTARNSVGSAEYQARINVRG---PPSI--RAMRNITAVAGR 349
Query: 894 SFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVS 1073
+ RV G S+ WYK+ + + P + ++ F+N L L + M D G Y C V
Sbjct: 350 DTLINCRVIGYPYYSIKWYKDAL-LLPDNHRQVVFENGTLKLTDVQKGM-DEGEYLCSVL 407
Query: 1074 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHV-RGSEPIRIQWLKAGR 1250
L S V K PP+ P S G+ L + C V G PIRI W K G+
Sbjct: 408 --IQPQLSISQSVHVAVKVPPLIQPFEFP-PASIGQLLYIPCVVSSGDMPIRITWRKDGQ 464
Query: 1251 EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXX 1430
I + + L+ V+ G+Y C ASN A + + + ++
Sbjct: 465 VIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPR---- 520
Query: 1431 XXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGK-------WRQLNQ 1589
FV +P + + V G P P V W K + +
Sbjct: 521 -----------FVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPL 569
Query: 1590 GGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG 1700
GRI Q + L IR + D G Y C A N G
Sbjct: 570 TGRI---QILPNSSLLIRHVLEEDIGYYLCQASNGVG 603
Score = 137 bits (344), Expect = 3e-32
Identities = 144/611 (23%), Positives = 235/611 (38%), Gaps = 26/611 (4%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
+K +G + L C L G+PE + WY+ + P + +N TL+ + SG
Sbjct: 153 LKTGIGSTVILSCTLMGSPEFTIRWYRNTELVLPGEAISIRGLSN-ETLLITSAQKSHSG 211
Query: 186 EYICRAENSVGEVSSSTFLTVQE--QKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y C A + +++ ++ SFS ++ + E L CA G+ P +
Sbjct: 212 AYQCFASRKAQTAQDFAIIVLEDGTPRIVSSFSEKVVNPGEQFSL----MCAAKGAPPPT 267
Query: 360 VSWFKDGRPL-KDGPNIQTSFL----DNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
V+W D P+ +DG + + ++ +N+ G Y CTA N +GSA A
Sbjct: 268 VTWALDDEPIVRDGSHRSNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNSVGSAEYQA 327
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
R+ + R PP + + AV G C V G + W KD + N++
Sbjct: 328 RINV---RGPPSIR-AMRNITAVAGRDTLINCRVIGYPYYSIKWYKD--ALLLPDNHRQV 381
Query: 705 YLENSAHLTILKVDKG-DTGQYTCYAVNEVGKDSCTAQLNIKERL-----IPPSFTKKLS 866
EN L + V KG D G+Y C + + QL+I + + +PP +
Sbjct: 382 VFENGT-LKLTDVQKGMDEGEYLCSVLIQ-------PQLSISQSVHVAVKVPPLI--QPF 431
Query: 867 ETVEETEGNSFRLEGRV-AGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMG 1043
E + G + V +G PI + W K+ I + I K LQ+ S+
Sbjct: 432 EFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLK 491
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPI 1223
G YTC SN A + ++++ P + V + + G L+C V G P
Sbjct: 492 HNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAG---VLNCSVDGYPPP 548
Query: 1224 RIQWLKAGREIKPSDRCSFSFANGTAVLE-----FKDVTKADAGDYVCKASNVAGSDTSK 1388
++ W A P +L + V + D G Y+C+ASN G+D SK
Sbjct: 549 KVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISK 608
Query: 1389 SKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKG 1568
S V S P + ++ G+ ++W KG
Sbjct: 609 S--------------MFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKG 654
Query: 1569 KW-----RQLNQGGRIFIHQKGDE--AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
R + I GDE + L+++ + DS + C A N +GE + L
Sbjct: 655 DTVIDPDRVMRYA--IATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLT 712
Query: 1728 VNERKKQEKIE 1760
V E ++E
Sbjct: 713 VQEPPDPPELE 723
Score = 83.6 bits (205), Expect = 4e-16
Identities = 102/436 (23%), Positives = 172/436 (39%), Gaps = 21/436 (4%)
Frame = +3
Query: 15 TVGDSASLQCQLA-GTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
++G + C ++ G I ++W K + + + + +++L + V +G Y
Sbjct: 437 SIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNY 496
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A N+ VS L V ++PP F Q + G V C+V G P V W
Sbjct: 497 TCIASNAAATVSRERQLIV---RVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWK 553
Query: 372 K---DGRPLKDGPNIQTSFLDNV--ATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
G P + P T + + ++L I G Y C A+N +G+ S + +
Sbjct: 554 HAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLT 613
Query: 537 TEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGG--NYQISYL 710
+ P A+ G + + C G +PI + W K + I Y I+
Sbjct: 614 V--KIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATK 671
Query: 711 ENS----AHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE 878
+N + L + D+GD+ ++C+A+N G+D QL ++E PP +
Sbjct: 672 DNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPEL------EIR 725
Query: 879 ETEGNSFRLE--GRVAGSQPIS--VAWYKNNVEI----HPTANCEITFKNNALLLQVKKA 1034
E + S L R G+ I+ YKN + T N T N A ++ + A
Sbjct: 726 EVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTI-NQANIVDLHPA 784
Query: 1035 SMGDAGLYTC-KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRG 1211
S+ +Y+ K+ S T S P PP+ D L PVT
Sbjct: 785 SVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPM-DVTLQPVT--------------- 828
Query: 1212 SEPIRIQWLKAGREIK 1259
S+ I++ W +E++
Sbjct: 829 SQSIQVTWKAPKKELQ 844
Score = 50.8 bits (120), Expect = 3e-06
Identities = 56/235 (23%), Positives = 85/235 (36%), Gaps = 6/235 (2%)
Frame = +3
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP--VTVSEGEFLQLSCHVRGSE 1217
D+G Y C+V+N GSA T ++ + +P LTP + G + LSC + GS
Sbjct: 117 DSGTYICEVTNTFGSAEATGTLTVIDP-----LHVTLTPKKLKTGIGSTVILSCTLMGSP 171
Query: 1218 PIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKV 1397
I+W + + P + S + +L K+ +G Y C AS A + + +
Sbjct: 172 EFTIRWYRNTELVLPGEAISIRGLSNETLL-ITSAQKSHSGAYQCFASRKAQTAQDFAII 230
Query: 1398 TXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWR 1577
DG VS V + + G P P V W
Sbjct: 231 VLE--------------DGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEP 276
Query: 1578 QLNQGG-RIFIHQKGDEAKLEIRDTTK---TDSGLYRCVAFNKHGEIESNVNLQV 1730
+ G R + D + + T D G+YRC A N G E + V
Sbjct: 277 IVRDGSHRSNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNSVGSAEYQARINV 331
>ref|XP_003127732.2| PREDICTED: basement membrane-specific heparan sulfate proteoglycan
core protein [Sus scrofa].
Length = 3308
Score = 147 bits (370), Expect = 3e-35
Identities = 148/607 (24%), Positives = 240/607 (39%), Gaps = 23/607 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G + L C + G V+W++ L A ++ H + L +QV DSGEY
Sbjct: 1743 VAEGQTLDLNCVVPGQAHAQVTWHRRGGSL--PARHQTHG----SRLRLHQVSPADSGEY 1796
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLP-PSFSRQLRDVQETV--GLPVVFECAVSGSEPISV 362
+CR G + SS +T++ P P ++ TV G + C V+G V
Sbjct: 1797 VCRVVLGSGPLESSVLVTIEASTAPGPIPPVRIESSSPTVAEGQTLDLNCVVAGQAHAQV 1856
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W+K G L ++ S L IFQ + AG+Y C A+N + A+ + + T+
Sbjct: 1857 TWYKRGGSLPARHQVRGS------RLYIFQASPADAGEYVCRASNGV-EATITVTVTRTQ 1909
Query: 543 GRN----PPFFDIPLAPVDAVV--GESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
G N P I + P + V G++ D C V G +V W K GG+
Sbjct: 1910 GANFAYPPGSTPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHK------RGGSLPAR 1963
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKER-------LIPPSFTKKL 863
+ + + L + +V D+G+Y C V + + I+ + PP +
Sbjct: 1964 HQTHGSLLRLYQVSPADSGEYVCRIVGGSVPLEASVLVTIEPADSVPALGVTPPVRIESS 2023
Query: 864 SETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMG 1043
S V EG + L V+G V W+K + + + L++ + +
Sbjct: 2024 SSHV--AEGQTLDLNCLVSGQAHAQVTWHKRG------GSLPARHQVHGSRLRLPQVTPA 2075
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPV-------TVSEGEFLQLSCH 1202
D+G Y C+V + +G+ + + I++ P + PV +++ G L L+C
Sbjct: 2076 DSGEYVCRVVSSSGTQEASVLVTIQQRLGPSRPQSVVYPVRIESSSDSLANGHTLDLNCL 2135
Query: 1203 VRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDT 1382
V P I W K G + + S L VT AD+G+YVC SN AGS
Sbjct: 2136 VASQAPHTITWYKRGGSLPSRHQIVGS------RLRIPQVTPADSGEYVCHVSNGAGSQE 2189
Query: 1383 SKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWT 1562
+ VT + E S VVE T V G P + W
Sbjct: 2190 TSLIVTIQGGGSSHVPSVSPPIR------IESSSPTVVEGQTLDLTCVVAGQPQATITWY 2243
Query: 1563 KGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNERK 1742
K +GG + + + L + + DSG Y C A N E+++ + V+
Sbjct: 2244 K-------RGGSLPAQHQAHGSHLRLHQMSVADSGEYVCRANNNIDAQEASIVVSVSPST 2296
Query: 1743 KQEKIEG 1763
+ + G
Sbjct: 2297 RSPAVPG 2303
Score = 144 bits (364), Expect = 1e-34
Identities = 140/596 (23%), Positives = 232/596 (38%), Gaps = 17/596 (2%)
Frame = +3
Query: 3 PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDS--- 173
PV+V G + +L+C AG P W T++ + + + Q+ S
Sbjct: 2700 PVRVKEGKAITLECVSAGEPRSSARW----TRIGAPTNLEQRLHGLLDSHTLLQISSAKP 2755
Query: 174 NDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSR-QLRDVQETV--GLPVVFECAVSG 344
+D+G Y+C A+N++G + V + P + Q+ + + TV G C+ +G
Sbjct: 2756 SDAGIYVCLAQNALGTAQKRVEVIVDTGIMAPGAPQVQVEEAELTVEAGHTATLRCSATG 2815
Query: 345 SEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
S ++ W K PL ++ TL I + + +GQY C AT+P G A ++
Sbjct: 2816 SPTPTIHWSKLRSPLPWQHQLEGD------TLIIPRVAQQDSGQYICNATSPAGHAEATI 2869
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQIS 704
L + +PP+ GE+ +C GT P+ W+ R GGN
Sbjct: 2870 ALHV---ESPPYATTVPEHASVRAGETVHLQCLAHGTPPLTFQWS------RVGGNLPSR 2920
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQL-------NIKERLIPPSFTKKL 863
L D+G+Y C N+VG AQ+ ++ P T +
Sbjct: 2921 VTARKEMLLFEPAAPEDSGRYRCRVTNKVGSAEAFAQVLVQGPSGSLPATPHPAGATPAV 2980
Query: 864 SETVE-ETE--GNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKA 1034
T + ET+ G S V Q + W K ++ P + +L+++
Sbjct: 2981 QVTPQLETKSIGASVEFHCIVPSDQGTQLRWVKEGGQLPPGHSVHDG------VLRIQNL 3034
Query: 1035 SMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPV-TVSEGEFLQLSCHVRG 1211
G Y C+ G A ++ +V++ P V T V TV G ++ C G
Sbjct: 3035 DQSCQGTYVCQAYGPWGQAQASAQLVVQA--LPSVLINIRTSVQTVVVGHSVEFECLALG 3092
Query: 1212 SEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS 1391
++ W K G ++P ++ V ADAG Y C A+N AG T++S
Sbjct: 3093 DPKPQVTWSKVGGPLRPG------IVQTGGIVRIAHVELADAGQYRCTATNAAG--TTQS 3144
Query: 1392 KVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGK 1571
V +S P +RV + A F G P P++ W+K
Sbjct: 3145 HVLLLVQALPQ--------------ISTPPEVRVPAGSAAVFPCMASGYPTPDISWSK-- 3188
Query: 1572 WRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
G + + + L + D+G Y C A N+ G++++ +LQV ER
Sbjct: 3189 -----LDGNLPPDSRLENNMLLLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER 3239
Score = 140 bits (352), Expect = 3e-33
Identities = 145/578 (25%), Positives = 222/578 (38%), Gaps = 9/578 (1%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G SL+CQ++G+P W + D + P++T + H + L F V +D+G Y
Sbjct: 1269 VPQGGPHSLRCQVSGSPPHYFYWSREDGRPLPSSTQQRH---QGSELHFPSVQPSDAGVY 1325
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV--GLPVVFECAVSGSEPI-SV 362
IC N +S L V E P ++V G V F C P ++
Sbjct: 1326 ICTCRNLHHANTSRAELLVTEAPSKPITVTVEEQRSQSVRPGTDVTFICTAKSKSPAYTL 1385
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W + L +G + T +D L I S AG Y CT +N +A L +
Sbjct: 1386 VWTR----LHNG-KLPTRAMDFNGILTIRNVQPSDAGTYVCTGSNMFAMDQGTATLHVQA 1440
Query: 543 GRNP--PFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
P P I + G+ A+F C TG + W GG
Sbjct: 1441 SGTPSAPMASIHPPQLTVQPGQLAEFRCSATGNPTPTLEWTGG-----PGGQLPQKAQIL 1495
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNS 896
L + V+ D QY C+A + G+ A L++ P + E + EG +
Sbjct: 1496 GGILRLPAVEPSDQAQYLCHAHSSAGQHVARAVLHVHGGNGPR--VQVSPERTQVHEGRT 1553
Query: 897 FRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSN 1076
RL R AG ++ W K + P A E T + L + + DAG Y C ++
Sbjct: 1554 VRLYCRAAGVPSATITWRKEGGSLPPQARSERT---DIATLLIPAITTADAGFYLCVATS 1610
Query: 1077 DAGSALCTSSIVIKEPK----KPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKA 1244
AG+A +V+ PPV + +P +V+EG+ L L+C V G ++ W K
Sbjct: 1611 PAGTAQARIQVVVLPASGASSPPPVRIESSSP-SVTEGQTLDLNCVVTGLAYTQVTWYKR 1669
Query: 1245 GREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXX 1424
G + P + +G L V+ AD+G+YVC+ N +G + V+
Sbjct: 1670 GGSLPPHAQ-----VHGPR-LRLSHVSPADSGEYVCRVENESGPKEASIIVSVLHSTHSA 1723
Query: 1425 XXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIF 1604
E S V E T V G V W + +GG +
Sbjct: 1724 YTPAPGSTHP---IRIESSSSHVAEGQTLDLNCVVPGQAHAQVTWHR-------RGGSLP 1773
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNV 1718
+ ++L + + DSG Y C G +ES+V
Sbjct: 1774 ARHQTHGSRLRLHQVSPADSGEYVCRVVLGSGPLESSV 1811
Score = 134 bits (338), Expect = 1e-31
Identities = 140/600 (23%), Positives = 227/600 (37%), Gaps = 23/600 (3%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+V G + L C+ AG P ++W K L P A + R ++ATL+ + + D+G
Sbjct: 1547 QVHEGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSE---RTDIATLLIPAITTADAGF 1603
Query: 189 YICRAENSVGEVSSS---TFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
Y+C A + G + L PP + T G + C V+G
Sbjct: 1604 YLCVATSPAGTAQARIQVVVLPASGASSPPPVRIESSSPSVTEGQTLDLNCVVTGLAYTQ 1663
Query: 360 VSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILT 539
V+W+K G L P+ Q + L + + +G+Y C N G +S + +
Sbjct: 1664 VTWYKRGGSLP--PHAQV----HGPRLRLSHVSPADSGEYVCRVENESGPKEASIIVSVL 1717
Query: 540 EGRNPPFFDIP---------LAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
+ + P + G++ D C V G +V W R GG+
Sbjct: 1718 HSTHSAYTPAPGSTHPIRIESSSSHVAEGQTLDLNCVVPGQAHAQVTWH------RRGGS 1771
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERL----IPPSFTKK 860
+ + + L + +V D+G+Y C V G + + I+ IPP +
Sbjct: 1772 LPARHQTHGSRLRLHQVSPADSGEYVCRVVLGSGPLESSVLVTIEASTAPGPIPPVRIES 1831
Query: 861 LSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASM 1040
S TV EG + L VAG V WYK + + L + +AS
Sbjct: 1832 SSPTV--AEGQTLDLNCVVAGQAHAQVTWYKRG------GSLPARHQVRGSRLYIFQASP 1883
Query: 1041 GDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVT-------VSEGEFLQLSC 1199
DAG Y C+ SN + + + V + + TP+ V+EG+ L L+C
Sbjct: 1884 ADAGEYVCRASNGVEATITVT--VTRTQGANFAYPPGSTPIRIEPSSSHVAEGQTLDLNC 1941
Query: 1200 HVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSD 1379
V G ++ W K G + + S +L V+ AD+G+YVC+ V GS
Sbjct: 1942 VVPGQAHAQVTWHKRGGSLPARHQTHGS------LLRLYQVSPADSGEYVCRI--VGGSV 1993
Query: 1380 TSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW 1559
++ V ++ E S V E T V G V W
Sbjct: 1994 PLEASVLVTIEPADSVPALGVTPPVRI----ESSSSHVAEGQTLDLNCLVSGQAHAQVTW 2049
Query: 1560 TKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNER 1739
K +GG + + ++L + T DSG Y C + G E++V + + +R
Sbjct: 2050 HK-------RGGSLPARHQVHGSRLRLPQVTPADSGEYVCRVVSSSGTQEASVLVTIQQR 2102
Score = 133 bits (334), Expect = 4e-31
Identities = 154/667 (23%), Positives = 260/667 (38%), Gaps = 33/667 (4%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYICR 200
G + L C +A ++WYK L P+ + R + QV DSGEY+C
Sbjct: 2127 GHTLDLNCLVASQAPHTITWYKRGGSL-PSRHQIVGSRLRIP-----QVTPADSGEYVCH 2180
Query: 201 AENSVGEVSSSTFLTVQE--QKLPPSFSRQLR--DVQETV--GLPVVFECAVSGSEPISV 362
N G +S +T+Q PS S +R TV G + C V+G ++
Sbjct: 2181 VSNGAGSQETSLIVTIQGGGSSHVPSVSPPIRIESSSPTVVEGQTLDLTCVVAGQPQATI 2240
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+W+K G L S L + Q + +G+Y C A N I + +S + ++
Sbjct: 2241 TWYKRGGSLPAQHQAHGSHL------RLHQMSVADSGEYVCRANNNIDAQEASIVVSVSP 2294
Query: 543 GRNPPFFDIPLAPV-------DAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQI 701
P P+ G++ D C V G +V W K GG+
Sbjct: 2295 STRSPAVPGGAMPIRIESSSSHVAEGQTLDLNCVVPGQAHAQVTWHK------RGGSLPT 2348
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKER-----LIP-----PSF 851
+ + + L + ++ D+G+Y C V+ G + + I+ L+P P
Sbjct: 2349 HHQAHGSRLRLYQLSPADSGEYVCRVVSSSGPLEASVLVTIEASGSGTVLVPAAGGTPPI 2408
Query: 852 TKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKK 1031
+ S + EG + L+ V G V W++ + + + LL++ +
Sbjct: 2409 RIETSSS-HVAEGQTLDLKCVVPGQAHAQVTWHRRG------GSLPARHQVHGPLLRLNQ 2461
Query: 1032 ASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT-PVT-------VSEGEFL 1187
S D+G Y+C+V+ +G+ + + I+ P+ L P+ V+EG+ L
Sbjct: 2462 VSPADSGEYSCRVTGSSGTQEASVLVTIEASSPSPIPAPGLAQPIYIEASSSHVTEGQTL 2521
Query: 1188 QLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNV 1367
L+C V G ++ W K G + + S L V++AD+G+YVC+ +
Sbjct: 2522 DLNCVVPGQAHAQVTWHKHGGSLPARHQTHGSR------LRLHQVSQADSGEYVCRVVGI 2575
Query: 1368 AGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIP 1547
+G + S V +P S V + A+F + P
Sbjct: 2576 SGPELEASFTVTVPPSAGSSYRLRSPV-----ISIDPPSSTVQQGQDASFKCLIHDGAAP 2630
Query: 1548 NVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
+W+ NQ +H + + + I T ++ G YRCVA N +G +S V L
Sbjct: 2631 ----ISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGAYRCVASNAYGVAQSVVTLS 2686
Query: 1728 VNERKKQEKI-EGDLRAMLKKTPVLK-KGAGEEEEIDIMELLKNVDPKEYEKYARMYGIT 1901
V+ + EG +R K L+ AGE + P E+ R++G+
Sbjct: 2687 VHGPPTVSVLPEGPVRVKEGKAITLECVSAGEPR--SSARWTRIGAPTNLEQ--RLHGLL 2742
Query: 1902 DFRGLLQ 1922
D LLQ
Sbjct: 2743 DSHTLLQ 2749
Score = 132 bits (331), Expect = 9e-31
Identities = 137/604 (22%), Positives = 238/604 (39%), Gaps = 31/604 (5%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G + L C ++G V+W+K L A +++H + L QV DSGEY
Sbjct: 2027 VAEGQTLDLNCLVSGQAHAQVTWHKRGGSL--PARHQVHG----SRLRLPQVTPADSGEY 2080
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPS------FSRQLRDVQETV--GLPVVFECAVSGS 347
+CR +S G +S +T+Q Q+L PS + ++ +++ G + C V+
Sbjct: 2081 VCRVVSSSGTQEASVLVTIQ-QRLGPSRPQSVVYPVRIESSSDSLANGHTLDLNCLVASQ 2139
Query: 348 EPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSAR 527
P +++W+K G L I S L I Q + +G+Y C +N GS +S
Sbjct: 2140 APHTITWYKRGGSLPSRHQIVGS------RLRIPQVTPADSGEYVCHVSNGAGSQETSLI 2193
Query: 528 LILTEGRN------PPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGG 689
+ + G + P I + V G++ D C V G + W K GG
Sbjct: 2194 VTIQGGGSSHVPSVSPPIRIESSSPTVVEGQTLDLTCVVAGQPQATITWYK------RGG 2247
Query: 690 NYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF------ 851
+ + + +HL + ++ D+G+Y C A N + + +++ P+
Sbjct: 2248 SLPAQHQAHGSHLRLHQMSVADSGEYVCRANNNIDAQEASIVVSVSPSTRSPAVPGGAMP 2307
Query: 852 TKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKK 1031
+ S + EG + L V G V W+K + PT + + + L++ +
Sbjct: 2308 IRIESSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSL-PTHH-----QAHGSRLRLYQ 2361
Query: 1032 ASMGDAGLYTCKVSNDAG----SALCT------SSIVIKEPKKPPVFDQHLTPVTVSEGE 1181
S D+G Y C+V + +G S L T ++++ P + V+EG+
Sbjct: 2362 LSPADSGEYVCRVVSSSGPLEASVLVTIEASGSGTVLVPAAGGTPPIRIETSSSHVAEGQ 2421
Query: 1182 FLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKAS 1361
L L C V G ++ W + G + + +L V+ AD+G+Y C+ +
Sbjct: 2422 TLDLKCVVPGQAHAQVTWHRRGGSLPARHQVH------GPLLRLNQVSPADSGEYSCRVT 2475
Query: 1362 NVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDP 1541
+G+ + VT E S V E T V G
Sbjct: 2476 GSSGTQEASVLVTIEASSPSPIPAPGLAQP----IYIEASSSHVTEGQTLDLNCVVPGQA 2531
Query: 1542 IPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHG-EIESNV 1718
V W K GG + + ++L + ++ DSG Y C G E+E++
Sbjct: 2532 HAQVTWHK-------HGGSLPARHQTHGSRLRLHQVSQADSGEYVCRVVGISGPELEASF 2584
Query: 1719 NLQV 1730
+ V
Sbjct: 2585 TVTV 2588
Score = 113 bits (283), Expect = 3e-25
Identities = 104/392 (26%), Positives = 156/392 (39%), Gaps = 13/392 (3%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYK--GDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V G++ LQC GTP + W + G+ R TA +M L+F DSG
Sbjct: 2888 VRAGETVHLQCLAHGTPPLTFQWSRVGGNLPSRVTARKEM--------LLFEPAAPEDSG 2939
Query: 186 EYICRAENSVGEVSSSTFLTVQ--EQKLP---------PSFSRQLRDVQETVGLPVVFEC 332
Y CR N VG + + VQ LP P+ + +++G V F C
Sbjct: 2940 RYRCRVTNKVGSAEAFAQVLVQGPSGSLPATPHPAGATPAVQVTPQLETKSIGASVEFHC 2999
Query: 333 AVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSA 512
V + + W K+G L G ++ L I D+S G Y C A P G A
Sbjct: 3000 IVPSDQGTQLRWVKEGGQLPPGHSVHDG------VLRIQNLDQSCQGTYVCQAYGPWGQA 3053
Query: 513 SSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN 692
+SA+L++ + +I + VVG S +FEC G +V W+K +R G
Sbjct: 3054 QASAQLVV-QALPSVLINIRTSVQTVVVGHSVEFECLALGDPKPQVTWSKVGGPLRPG-- 3110
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSET 872
++ + I V+ D GQY C A N G L ++ +P T
Sbjct: 3111 ----IVQTGGIVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQA--LPQISTPP---E 3161
Query: 873 VEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAG 1052
V G++ +G ++W K + + P + E NN LLL + DAG
Sbjct: 3162 VRVPAGSAAVFPCMASGYPTPDISWSKLDGNLPPDSRLE----NNMLLLPSVRPQ--DAG 3215
Query: 1053 LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQ 1148
Y C +N G + + + E + P F Q
Sbjct: 3216 TYVCTATNRQGKVKAFAHLQVPE-RVVPYFTQ 3246
Score = 65.5 bits (158), Expect = 1e-10
Identities = 62/211 (29%), Positives = 81/211 (38%), Gaps = 5/211 (2%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V VG S +C G P+ V+W K LRP + V+ D+G+Y
Sbjct: 3078 VVVGHSVEFECLALGDPKPQVTWSKVGGPLRPGIV------QTGGIVRIAHVELADAGQY 3131
Query: 192 ICRAENSVGEVSSSTFLTVQ---EQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
C A N+ G S L VQ + PP +V+ G VF C SG +
Sbjct: 3132 RCTATNAAGTTQSHVLLLVQALPQISTPP-------EVRVPAGSAAVFPCMASGYPTPDI 3184
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
SW K DG S L+N L + AG Y CTATN G + A L + E
Sbjct: 3185 SWSK-----LDGNLPPDSRLENNMLL-LPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPE 3238
Query: 543 GRNPPFFDIP--LAPVDAVVGESADFECHVT 629
P F P P+ + FE +T
Sbjct: 3239 RVVPYFTQTPHSFLPLPTIKDAYRKFEIKIT 3269
>ref|XP_003360572.1| PREDICTED: matrix-remodeling-associated protein 5 [Sus scrofa].
Length = 2773
Score = 135 bits (341), Expect = 6e-32
Identities = 122/481 (25%), Positives = 190/481 (39%), Gaps = 17/481 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
V+V GD ++ C+ G P V+W +L P ++ K + TL+ + +DSG
Sbjct: 2301 VQVPYGDVVTVACEAKGEPTPRVTWLSPTNRLIPASSEKYQIYPD-GTLLIQKAQRSDSG 2359
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLP----PSFSRQLRDVQETVGLPVVFECAVSGSEP 353
Y C NS GE ++ V Q P +R++ VG + +C G+
Sbjct: 2360 NYTCVVRNSAGEDRKMVWILVHVQAPRINGNPDAITTVREIAP-VGSRKLIDCQAEGTPM 2418
Query: 354 ISVSW-FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
V W F +G L + + TL+I + +S + Q C N G A +L
Sbjct: 2419 PRVLWAFPEGVVLPAPYHGNRITIHGNGTLDIRRLRKSDSVQLVCIGRNEGGEARLIVQL 2478
Query: 531 ILTEGRNPPFFDIPLAP-VDAVVGESADFECHVTGTQPIKVAWAKDNR-EIRSGGNYQIS 704
+ E P F P++ + A+ G + C GT + W NR E+RSG Q
Sbjct: 2479 TVLEPVEKPIFHDPVSEKITAMAGHTISLNCSAAGTPTPTLLWVLPNRTELRSGQQLQRF 2538
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
Y + L I + D G Y C A N G L + + P + + +
Sbjct: 2539 YHKGDGKLHISDLSSVDAGAYRCVARNSAGYTERLVSLKVG---LKPETSNRYHNLISII 2595
Query: 885 EGNSFRLEGRVAGSQPISVAWYKNN--VEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
G + L G + + +W N V P A T N L V+ AS+ D G Y
Sbjct: 2596 NGETLHLPCAPPGGRQVRSSWTLPNGLVLEGPQARGRFTLWENGTLT-VRDASVFDRGTY 2654
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSE-GEFLQLSCHVRGSEPIRIQW 1235
CK + G ++ +++ PP TPV + G ++L+C V I W
Sbjct: 2655 VCKADTEYGPSVANVPVIVIA--YPPRITSEPTPVIYTRPGNMVKLNCMVMAIPKAEITW 2712
Query: 1236 -------LKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSK 1394
L AG + + F + L + T+ DAG Y C A N+ GSD+ +
Sbjct: 2713 ELPDKSLLMAGTQPR---LYGHRFLHPQGSLTIQQATQRDAGFYKCSAKNILGSDSKTTY 2769
Query: 1395 V 1397
+
Sbjct: 2770 I 2770
Score = 128 bits (321), Expect = 1e-29
Identities = 149/601 (24%), Positives = 222/601 (36%), Gaps = 27/601 (4%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPT--------ATYKMHFRNNVATLVFNQ 164
+V G + C G P +SW D L + K + N TL FN+
Sbjct: 2199 RVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDGGGRAKRYVVFNNGTLYFNE 2258
Query: 165 VDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSF-SRQLRDVQETVGLPVVFECAVS 341
V + G+Y C AEN VG+ + + V + PP+ ++ VQ G V C
Sbjct: 2259 VGMREEGDYTCVAENQVGKDEMTVHVKVVTE--PPAIRNKTYSVVQVPYGDVVTVACEAK 2316
Query: 342 GSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSS 521
G V+W L + + + TL I + RS +G Y+C N G
Sbjct: 2317 GEPTPRVTWLSPTNRLIPASSEKYQIYPD-GTLLIQKAQRSDSGNYTCVVRNSAGEDRKM 2375
Query: 522 ARLILTEGRNPPFFDIPLAPVD----AVVGESADFECHVTGTQPIKVAWAKDNREIRSG- 686
IL + P P A A VG +C GT +V WA +
Sbjct: 2376 V-WILVHVQAPRINGNPDAITTVREIAPVGSRKLIDCQAEGTPMPRVLWAFPEGVVLPAP 2434
Query: 687 --GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKK 860
GN +I+ + + L I ++ K D+ Q C NE G+ QL + E + P F
Sbjct: 2435 YHGN-RIT-IHGNGTLDIRRLRKSDSVQLVCIGRNEGGEARLIVQLTVLEPVEKPIFHDP 2492
Query: 861 LSETVEETEGNSFRLEGRVAGSQPISVAW-YKNNVEIHPTANCEITFKNNALLLQVKKAS 1037
+SE + G++ L AG+ ++ W N E+ + + L + S
Sbjct: 2493 VSEKITAMAGHTISLNCSAAGTPTPTLLWVLPNRTELRSGQQLQRFYHKGDGKLHISDLS 2552
Query: 1038 MGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSE 1217
DAG Y C N AG + +K KP +++ +++ GE L L C G
Sbjct: 2553 SVDAGAYRCVARNSAG--YTERLVSLKVGLKPETSNRYHNLISIINGETLHLPCAPPGGR 2610
Query: 1218 PIRIQW-LKAGREIK-PSDRCSFS-FANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSK 1388
+R W L G ++ P R F+ + NGT L +D + D G YVCKA G +
Sbjct: 2611 QVRSSWTLPNGLVLEGPQARGRFTLWENGT--LTVRDASVFDRGTYVCKADTEYGPSVAN 2668
Query: 1389 SKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFI-AKVGGDPIPNVKWTK 1565
V SEP + + V P + W
Sbjct: 2669 VPVIVIAYPPR--------------ITSEPTPVIYTRPGNMVKLNCMVMAIPKAEITWEL 2714
Query: 1566 GKWRQLNQG------GRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
L G G F+H +G L I+ T+ D+G Y+C A N G +
Sbjct: 2715 PDKSLLMAGTQPRLYGHRFLHPQG---SLTIQQATQRDAGFYKCSAKNILGSDSKTTYIH 2771
Query: 1728 V 1730
V
Sbjct: 2772 V 2772
Score = 115 bits (289), Expect = 7e-26
Identities = 150/599 (25%), Positives = 214/599 (35%), Gaps = 33/599 (5%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNV---ATLVFNQVDSN 176
V VT C+ G P+ V+W K T T ++ R V T V V
Sbjct: 1808 VTVTAETDVVFPCEATGQPQPFVTWTKVSTGALMTPNTRVQ-RFEVLKNGTFVIRNVQVQ 1866
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
D G+Y+C A+N G LTV Q+ P + DV +G + EC G+
Sbjct: 1867 DGGQYMCTAKNLHGADRMVVLLTVAVQQ-PQILASHYEDVTVYLGDTIAMECLAKGTPAP 1925
Query: 357 SVSW-FKDGRPLKDGPNIQTSF-LDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
+SW F D R + ++ L TL+I + S G Y C A+N G+ S + RL
Sbjct: 1926 QISWIFPDRRVWQAVSPVEGRITLHENRTLSIKEASFSDRGVYKCVASNAAGADSLAIRL 1985
Query: 531 ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAK-DNREIRSG----GNY 695
+ P L + G S C V W D +IR GN
Sbjct: 1986 HVA-ALPPVIQQEKLENISVPPGLSIHIHCTAKAAPLPSVRWVLWDGTQIRPSQFLHGNL 2044
Query: 696 QISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETV 875
++ + L I + D+G+Y C A N VG QL++ T +
Sbjct: 2045 ---FVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRAVQLSVMRAAANARITGTSPQRT 2101
Query: 876 EETEGNSFRLEGRVAGSQPISVAW---YKNNVEIHPTANCEI-TFKNNALLLQVKKASMG 1043
+ G + RL+ +G + W K ++ + + + F N LL VK +
Sbjct: 2102 DVRYGGTLRLDCSASGDPWPRILWRLPSKRMIDALFSFDTRMKVFANGTLL--VKSVTDK 2159
Query: 1044 DAGLYTCKVSNDAGSALCTSSI-VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEP 1220
DAG Y C N G + V+ P K + + V G L++ C G
Sbjct: 2160 DAGDYLCIARNKVGDDFVMLQVNVVMRPAK--IEHKEENDHRVFYGGDLKVDCVATGLPN 2217
Query: 1221 IRIQWLKAGREIKPSDRCS----------FSFANGTAVLEFKDVTKADAGDYVCKASNVA 1370
I W + S S F NGT L F +V + GDY C A N
Sbjct: 2218 PEISWSLPDGSLVNSFMQSDDGGGRAKRYVVFNNGT--LYFNEVGMREEGDYTCVAENQV 2275
Query: 1371 GSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIR--------VVEKTTATFIAK 1526
G D V V+EP +IR V T +
Sbjct: 2276 GKDEMTVHVK---------------------VVTEPPAIRNKTYSVVQVPYGDVVTVACE 2314
Query: 1527 VGGDPIPNVKWTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
G+P P V W R + + Q + L I+ ++DSG Y CV N GE
Sbjct: 2315 AKGEPTPRVTWLSPTNRLIPASSEKY--QIYPDGTLLIQKAQRSDSGNYTCVVRNSAGE 2371
Score = 107 bits (266), Expect = 3e-23
Identities = 135/593 (22%), Positives = 219/593 (36%), Gaps = 24/593 (4%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNV---ATLVFNQVDSNDS 182
V G + L C +G P + W + +K A + R V TL+ V D+
Sbjct: 2103 VRYGGTLRLDCSASGDPWPRILW-RLPSKRMIDALFSFDTRMKVFANGTLLVKSVTDKDA 2161
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFS-RQLRDVQETVGLPVVFECAVSGSEPIS 359
G+Y+C A N VG+ L V P ++ D + G + +C +G
Sbjct: 2162 GDYLCIARNKVGD--DFVMLQVNVVMRPAKIEHKEENDHRVFYGGDLKVDCVATGLPNPE 2219
Query: 360 VSW-FKDGRPLKD-------GPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSAS 515
+SW DG + G + + N TL + G Y+C A N +G
Sbjct: 2220 ISWSLPDGSLVNSFMQSDDGGGRAKRYVVFNNGTLYFNEVGMREEGDYTCVAENQVGKDE 2279
Query: 516 SSARL-ILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREI--RSG 686
+ + ++TE P + + V G+ C G +V W + S
Sbjct: 2280 MTVHVKVVTE--PPAIRNKTYSVVQVPYGDVVTVACEAKGEPTPRVTWLSPTNRLIPASS 2337
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLS 866
YQI Y + + L I K + D+G YTC N G+D + + + +
Sbjct: 2338 EKYQI-YPDGT--LLIQKAQRSDSGNYTCVVRNSAGEDRKMVWILVHVQAPRINGNPDAI 2394
Query: 867 ETVEETE--GNSFRLEGRVAGSQPISVAW-YKNNVEI-HPTANCEITFKNNALLLQVKKA 1034
TV E G+ ++ + G+ V W + V + P IT N L +++
Sbjct: 2395 TTVREIAPVGSRKLIDCQAEGTPMPRVLWAFPEGVVLPAPYHGNRITIHGNG-TLDIRRL 2453
Query: 1035 SMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVF-DQHLTPVTVSEGEFLQLSCHVRG 1211
D+ C N+ G A + + EP + P+F D +T G + L+C G
Sbjct: 2454 RKSDSVQLVCIGRNEGGEARLIVQLTVLEPVEKPIFHDPVSEKITAMAGHTISLNCSAAG 2513
Query: 1212 SEPIRIQWLKAGR-EIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAG--SDT 1382
+ + W+ R E++ + + G L D++ DAG Y C A N AG
Sbjct: 2514 TPTPTLLWVLPNRTELRSGQQLQRFYHKGDGKLHISDLSSVDAGAYRCVARNSAGYTERL 2573
Query: 1383 SKSKVTXXXXXXXXXXXXXXXVDGK-LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW 1559
KV ++G+ L P R V + +PN
Sbjct: 2574 VSLKVGLKPETSNRYHNLISIINGETLHLPCAPPGGRQVRSSWT----------LPNGLV 2623
Query: 1560 TKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNV 1718
+G + GR + + G L +RD + D G Y C A ++G +NV
Sbjct: 2624 LEGPQAR----GRFTLWENG---TLTVRDASVFDRGTYVCKADTEYGPSVANV 2669
Score = 103 bits (258), Expect = 3e-22
Identities = 127/522 (24%), Positives = 197/522 (37%), Gaps = 21/522 (4%)
Frame = +3
Query: 228 SSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNI 407
+S F T+ E+ P ++ V T VVF C +G V+W K PN
Sbjct: 1788 ASKFWTLGEK--PHIVTKSPPSVTVTAETDVVFPCEATGQPQPFVTWTKVSTGALMTPNT 1845
Query: 408 QTSFLDNV--ATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAP 581
+ + + T I GQY CTA N G A L+ + P
Sbjct: 1846 RVQRFEVLKNGTFVIRNVQVQDGGQYMCTAKNLHG-ADRMVVLLTVAVQQPQILASHYED 1904
Query: 582 VDAVVGESADFECHVTGTQPIKVAWAKDNREIR---SGGNYQISYLENSAHLTILKVDKG 752
V +G++ EC GT +++W +R + S +I+ EN L+I +
Sbjct: 1905 VTVYLGDTIAMECLAKGTPAPQISWIFPDRRVWQAVSPVEGRITLHENRT-LSIKEASFS 1963
Query: 753 DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFRLEGRVAGSQP 932
D G Y C A N G DS +L++ +PP ++ E + G S + +
Sbjct: 1964 DRGVYKCVASNAAGADSLAIRLHVAA--LPPVIQQEKLENISVPPGLSIHIHCTAKAAPL 2021
Query: 933 ISVAWYK-NNVEIHPTANCE---ITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCT 1100
SV W + +I P+ F N L ++ + D+G Y C +N GSA
Sbjct: 2022 PSVRWVLWDGTQIRPSQFLHGNLFVFPNGTLY--IRNLAPKDSGRYECVAANLVGSARRA 2079
Query: 1101 SSI-VIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPS---- 1265
+ V++ + V G L+L C G RI W + + +
Sbjct: 2080 VQLSVMRAAANARITGTSPQRTDVRYGGTLRLDCSASGDPWPRILWRLPSKRMIDALFSF 2139
Query: 1266 DRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXX 1445
D FANGT ++ K VT DAGDY+C A N G D +V
Sbjct: 2140 DTRMKVFANGTLLV--KSVTDKDAGDYLCIARNKVGDDFVMLQVNVVMRPAKIEHKEEN- 2196
Query: 1446 VDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQ-------GGRIF 1604
D ++F+ + + V G P P + W+ +N GGR
Sbjct: 2197 -DHRVFYGGDLKVDCVAT-----------GLPNPEISWSLPDGSLVNSFMQSDDGGGRAK 2244
Query: 1605 IHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ + L + + G Y CVA N+ G+ E V+++V
Sbjct: 2245 RYVVFNNGTLYFNEVGMREEGDYTCVAENQVGKDEMTVHVKV 2286
Score = 74.7 bits (182), Expect = 2e-13
Identities = 70/284 (24%), Positives = 107/284 (37%), Gaps = 11/284 (3%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGD-TKLRPTATYKMHFRNNVATLVFNQVDSNDS 182
+ G + SL C AGTP + W + T+LR + + L + + S D+
Sbjct: 2497 ITAMAGHTISLNCSAAGTPTPTLLWVLPNRTELRSGQQLQRFYHKGDGKLHISDLSSVDA 2556
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDV-----QETVGLPVVFECAVSGS 347
G Y C A NS G L V L P S + ++ ET+ LP CA G
Sbjct: 2557 GAYRCVARNSAGYTERLVSLKVG---LKPETSNRYHNLISIINGETLHLP----CAPPGG 2609
Query: 348 EPISVSWFKDGRPLKDGPNIQTSF-LDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
+ SW + +GP + F L TL + G Y C A G + ++
Sbjct: 2610 RQVRSSWTLPNGLVLEGPQARGRFTLWENGTLTVRDASVFDRGTYVCKADTEYGPSVANV 2669
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGN---- 692
+I+ P P + G C V ++ W ++ + G
Sbjct: 2670 PVIVI-AYPPRITSEPTPVIYTRPGNMVKLNCMVMAIPKAEITWELPDKSLLMAGTQPRL 2728
Query: 693 YQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI 824
Y +L LTI + + D G Y C A N +G DS T +++
Sbjct: 2729 YGHRFLHPQGSLTIQQATQRDAGFYKCSAKNILGSDSKTTYIHV 2772
Score = 71.6 bits (174), Expect = 1e-12
Identities = 75/319 (23%), Positives = 115/319 (36%), Gaps = 12/319 (3%)
Frame = +3
Query: 843 PSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEI----TFKNNA 1010
P K +V T G V W K + T N + KN
Sbjct: 1798 PHIVTKSPPSVTVTAETDVVFPCEATGQPQPFVTWTKVSTGALMTPNTRVQRFEVLKNGT 1857
Query: 1011 LLLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQ 1190
+ ++ + D G Y C N G+ + + ++P + H VTV G+ +
Sbjct: 1858 FV--IRNVQVQDGGQYMCTAKNLHGADRMVVLLTVAV-QQPQILASHYEDVTVYLGDTIA 1914
Query: 1191 LSCHVRGSEPIRIQWLKAGREI----KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKA 1358
+ C +G+ +I W+ R + P + N T L K+ + +D G Y C A
Sbjct: 1915 MECLAKGTPAPQISWIFPDRRVWQAVSPVEGRITLHENRT--LSIKEASFSDRGVYKCVA 1972
Query: 1359 SNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGD 1538
SN AG+D+ ++ KL +S P + + TA
Sbjct: 1973 SNAAGADSLAIRLHVAALPPVIQQE-------KLENISVPPGLSIHIHCTAK------AA 2019
Query: 1539 PIPNVKWTKGKWRQLNQG----GRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEI 1706
P+P+V+W Q+ G +F+ G L IR+ DSG Y CVA N G
Sbjct: 2020 PLPSVRWVLWDGTQIRPSQFLHGNLFVFPNGT---LYIRNLAPKDSGRYECVAANLVGSA 2076
Query: 1707 ESNVNLQVNERKKQEKIEG 1763
V L V +I G
Sbjct: 2077 RRAVQLSVMRAAANARITG 2095
Score = 58.9 bits (141), Expect = 1e-08
Identities = 50/180 (27%), Positives = 73/180 (40%), Gaps = 5/180 (2%)
Frame = +3
Query: 309 GLPVVFECAVSGSEPISVSW-FKDGRPLK---DGPNIQTSFLDNVATLNIFQTDRSFAGQ 476
G P C V SE S+ W DG LK + P+ + S L + L I T+ S AG
Sbjct: 437 GSPCQLSCNVKASERPSIWWVLPDGSVLKAPLEDPDGRVSVLTS-GWLKIKSTEPSDAGL 495
Query: 477 YSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAW 656
Y C A +L + P D + GE CH +++W
Sbjct: 496 YQCIA-RVRDEVDRMVYRVLVQPPAPQAPDGHTVTIQKNPGEPVTLPCHALAVPEAQISW 554
Query: 657 AKDNREIRSG-GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKER 833
N+ I + N +YL L+I +V D+G Y C AVN+ G D T + + ++
Sbjct: 555 ILPNKRILNDMANTSHAYLLADGTLSIPRVQGSDSGYYRCVAVNQHGADHFTVGVAVHKK 614
Score = 50.4 bits (119), Expect = 4e-06
Identities = 46/188 (24%), Positives = 78/188 (41%), Gaps = 6/188 (3%)
Frame = +3
Query: 834 LIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNAL 1013
+I PS + ++TV EG+ +L V S+ S+ W + + + + + L
Sbjct: 421 MIEPSTAVQRAQTV--LEGSPCQLSCNVKASERPSIWWVLPDGSVLKAPLEDPDGRVSVL 478
Query: 1014 L---LQVKKASMGDAGLYTC--KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEG 1178
L++K DAGLY C +V ++ + V+ +P P D H + + G
Sbjct: 479 TSGWLKIKSTEPSDAGLYQCIARVRDEVDRMVYR---VLVQPPAPQAPDGHTVTIQKNPG 535
Query: 1179 EFLQLSCHVRGSEPIRIQWLKAGREI-KPSDRCSFSFANGTAVLEFKDVTKADAGDYVCK 1355
E + L CH +I W+ + I S ++ L V +D+G Y C
Sbjct: 536 EPVTLPCHALAVPEAQISWILPNKRILNDMANTSHAYLLADGTLSIPRVQGSDSGYYRCV 595
Query: 1356 ASNVAGSD 1379
A N G+D
Sbjct: 596 AVNQHGAD 603
>ref|XP_003132540.1| PREDICTED: immunoglobulin superfamily member 10 [Sus scrofa].
Length = 2601
Score = 133 bits (335), Expect = 3e-31
Identities = 151/603 (25%), Positives = 229/603 (37%), Gaps = 33/603 (5%)
Frame = +3
Query: 27 SASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVA------TLVFNQVDSNDSGE 188
+ ++C++ G P +SW + T K N A TLV + + D G
Sbjct: 1741 TVKVKCRVEGRPSPTISWILANQ----TVVSKSSEGNGQALVMSDGTLVIHNISIYDRGF 1796
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETV-GLPVVFECAVSGSEPISVS 365
Y C A N VG+ S + +Q PP Q R V G + C G+ +
Sbjct: 1797 YKCMASNPVGQ--DSLLIKIQVIAAPPVILEQKRQVITGAWGKSLKLPCTAKGTPQPGIH 1854
Query: 366 W-FKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
W DG +K I + FL + TL I S G Y C AT+ GS L + +
Sbjct: 1855 WVLSDGTEVKPLQFINSKFLFSNGTLLIRNMASSDTGTYECIATSSTGSERRVVILTVED 1914
Query: 543 GRNPPFFDIPLAPVDAV-VGESADFECHVTGTQPIKVAWAKDNREI-----RSGGNYQIS 704
P + V +G+ C G K+ W ++ + R G +
Sbjct: 1915 QETIPRIESASQKWTEVNLGDKLLLNCSAIGEPKPKIIWRLPSKAVVDQWHRMGSRIHV- 1973
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
Y S L I V + D+G Y C A N++G D ++++ + P K +
Sbjct: 1974 YPNGS--LLIGSVTEKDSGDYLCVARNKMGDDLTLMHVSLRWK--PAKIDHKQHFRKQAF 2029
Query: 885 EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTA---------NCEITFKNNALLLQVKKAS 1037
G F+++ + +GS ++W + + A N T +N L K
Sbjct: 2030 HGKDFQVDCKASGSPLPEISWSLPDGTVINNAMQADDSGLRNRRFTLFDNGTLY-FNKVG 2088
Query: 1038 MGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSE 1217
M + G YTC N G + + P + V G+ L C V G
Sbjct: 2089 MAEEGDYTCYAQNTLGKDEMKVHLTVITAA-PRIRQGSRANTRVKAGDTAVLDCEVIGEP 2147
Query: 1218 PIRIQWLKAGREIKPSDRCSFSF-ANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSK 1394
+I WL ++ + ++F NG+ L V D+G+YVC A N +G DT SK
Sbjct: 2148 KPKIFWLLPSSDVISFSQDRYTFHPNGS--LSISKVKLLDSGEYVCVARNPSGDDTKMSK 2205
Query: 1395 VTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTAT------FIAKVGGDPIPNVK 1556
+ V K ++ + + V K TA F + G P P +
Sbjct: 2206 L---------------DVVAKPPLINGLYTNKTVMKATAVRHSKKHFDCRAEGTPSPQIM 2250
Query: 1557 WTKGKWRQLN---QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQ 1727
W L G RI +H+ G LEIR+ +DS + CVA N+ GE V L+
Sbjct: 2251 WIMPDNIFLTAPYYGSRITVHKNG---TLEIRNVRLSDSADFTCVARNEGGESVLVVQLE 2307
Query: 1728 VNE 1736
V E
Sbjct: 2308 VLE 2310
Score = 133 bits (335), Expect = 3e-31
Identities = 145/593 (24%), Positives = 224/593 (37%), Gaps = 23/593 (3%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYK--MHFRN------NVATLVFNQVDSN 176
G + C+ +G+P +SW D + A RN + TL FN+V
Sbjct: 2031 GKDFQVDCKASGSPLPEISWSLPDGTVINNAMQADDSGLRNRRFTLFDNGTLYFNKVGMA 2090
Query: 177 DSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPI 356
+ G+Y C A+N++G+ LTV P + + G V +C V G
Sbjct: 2091 EEGDYTCYAQNTLGKDEMKVHLTVITAA-PRIRQGSRANTRVKAGDTAVLDCEVIGEPKP 2149
Query: 357 SVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLIL 536
+ W + + +F N +L+I + +G+Y C A NP G + ++L +
Sbjct: 2150 KIFWLLPSSDVISFSQDRYTFHPN-GSLSISKVKLLDSGEYVCVARNPSGDDTKMSKLDV 2208
Query: 537 TEGRNPP-----FFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNY-- 695
PP + + + AV F+C GT ++ W + + Y
Sbjct: 2209 VA--KPPLINGLYTNKTVMKATAVRHSKKHFDCRAEGTPSPQIMWIMPDNIFLTAPYYGS 2266
Query: 696 QISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETV 875
+I+ +N L I V D+ +TC A NE G+ QL + E L P+F +E +
Sbjct: 2267 RITVHKNGT-LEIRNVRLSDSADFTCVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKI 2325
Query: 876 EETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTA--NCEITFKNNALLLQVKKASMGDA 1049
G L V G+ P + W N P N + +N + + K + DA
Sbjct: 2326 VAQLGKPTALNCSVDGNPPPEIIWILPNGTQFPNGPPNSQHLIASNGSFI-IYKTTRDDA 2384
Query: 1050 GLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRI 1229
G Y C N G IV++ +KP + V G+ L L C GS I
Sbjct: 2385 GKYRCGARNKVG--YIEKLIVLEIGQKPIILTYARETVYCISGDSLSLHCVSNGSPKPHI 2442
Query: 1230 QWLKAGREI--KPSDRCSFSF-ANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVT 1400
+W + +P + F NGT V+ KD T D G+Y+CKA N G V
Sbjct: 2443 KWTVPSGYVLDRPQINGKYIFHENGTLVI--KDATAYDRGNYICKAQNSVGHAVITVPV- 2499
Query: 1401 XXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW---TKGK 1571
+ +L P+SIR G P P V W
Sbjct: 2500 -------MVVAYPPRITNRL-----PRSIRTRTGVALQLPCVALGVPRPEVTWEMPDHSL 2547
Query: 1572 WRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
+ + G I L I++ +DSG+Y+C A N G + +QV
Sbjct: 2548 FSGADIGRMSGIQSFHPRGTLVIQNPQTSDSGIYKCTAKNPLGSDYATTYIQV 2600
Score = 129 bits (323), Expect = 8e-30
Identities = 137/596 (22%), Positives = 231/596 (38%), Gaps = 22/596 (3%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNV---ATLVFNQVDSND 179
+V +GD L C G P+ + W + +K ++M R +V +L+ V D
Sbjct: 1930 EVNLGDKLLLNCSAIGEPKPKIIW-RLPSKAVVDQWHRMGSRIHVYPNGSLLIGSVTEKD 1988
Query: 180 SGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPIS 359
SG+Y+C A N +G+ + ++++ + + R Q G +C SGS
Sbjct: 1989 SGDYLCVARNKMGDDLTLMHVSLRWKPAKIDHKQHFRK-QAFHGKDFQVDCKASGSPLPE 2047
Query: 360 VSW-FKDGRPLKDGPNIQTSFLDN-------VATLNIFQTDRSFAGQYSCTATNPIGSAS 515
+SW DG + + S L N TL + + G Y+C A N +G
Sbjct: 2048 ISWSLPDGTVINNAMQADDSGLRNRRFTLFDNGTLYFNKVGMAEEGDYTCYAQNTLGKDE 2107
Query: 516 SSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNY 695
L + P A G++A +C V G K+ W + ++ S
Sbjct: 2108 MKVHLTVITAA-PRIRQGSRANTRVKAGDTAVLDCEVIGEPKPKIFWLLPSSDVISFSQD 2166
Query: 696 QISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI--KERLIPPSFTKKLSE 869
+ ++ N + L+I KV D+G+Y C A N G D+ ++L++ K LI +T K
Sbjct: 2167 RYTFHPNGS-LSISKVKLLDSGEYVCVARNPSGDDTKMSKLDVVAKPPLINGLYTNKTVM 2225
Query: 870 TVEETEGNSFRLEGRVAGSQPISVAWY--KNNVEIHPTANCEITFKNNALLLQVKKASMG 1043
+ + R G+ + W N P IT N L+++ +
Sbjct: 2226 KATAVRHSKKHFDCRAEGTPSPQIMWIMPDNIFLTAPYYGSRITVHKNG-TLEIRNVRLS 2284
Query: 1044 DAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSE-GEFLQLSCHVRGSEP 1220
D+ +TC N+ G ++ + + E + P F V++ G+ L+C V G+ P
Sbjct: 2285 DSADFTCVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKPTALNCSVDGNPP 2344
Query: 1221 IRIQW-LKAGREIK--PSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKS 1391
I W L G + P + +NG+ ++ T+ DAG Y C A N G
Sbjct: 2345 PEIIWILPNGTQFPNGPPNSQHLIASNGSFII--YKTTRDDAGKYRCGARNKVG------ 2396
Query: 1392 KVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGK 1571
+ +++ + + + G P P++KWT
Sbjct: 2397 --------YIEKLIVLEIGQKPIILTYARETVYCISGDSLSLHCVSNGSPKPHIKWTVPS 2448
Query: 1572 WRQLNQ---GGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
L++ G+ H+ G L I+D T D G Y C A N G V + V
Sbjct: 2449 GYVLDRPQINGKYIFHENG---TLVIKDATAYDRGNYICKAQNSVGHAVITVPVMV 2501
Score = 127 bits (320), Expect = 2e-29
Identities = 142/601 (23%), Positives = 229/601 (38%), Gaps = 28/601 (4%)
Frame = +3
Query: 21 GDSASLQCQLAGTPEIGVSWYKGD-TKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYIC 197
G S L C GTP+ G+ W D T+++P F + TL+ + S+D+G Y C
Sbjct: 1836 GKSLKLPCTAKGTPQPGIHWVLSDGTEVKPLQFINSKFLFSNGTLLIRNMASSDTGTYEC 1895
Query: 198 RAENSVGEVSSSTFLTVQEQK-LPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFK 374
A +S G LTV++Q+ +P S + + +G ++ C+ G + W
Sbjct: 1896 IATSSTGSERRVVILTVEDQETIPRIESASQKWTEVNLGDKLLLNCSAIGEPKPKIIWRL 1955
Query: 375 DGRPLKDGPNIQTSFLDNV--ATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGR 548
+ + D + S + +L I +G Y C A N +G + + L R
Sbjct: 1956 PSKAVVDQWHRMGSRIHVYPNGSLLIGSVTEKDSGDYLCVARNKMGDDLTLMHVSL---R 2012
Query: 549 NPPFFDIPLAPVD--------AVVGESADFECHVTGTQPIKVAWA-KDNREIRSGGNYQI 701
P A +D A G+ +C +G+ +++W+ D I +
Sbjct: 2013 WKP------AKIDHKQHFRKQAFHGKDFQVDCKASGSPLPEISWSLPDGTVINNAMQADD 2066
Query: 702 SYLEN-------SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKK 860
S L N + L KV + G YTCYA N +GKD L + P +
Sbjct: 2067 SGLRNRRFTLFDNGTLYFNKVGMAEEGDYTCYAQNTLGKDEMKVHLTV--ITAAPRIRQG 2124
Query: 861 LSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASM 1040
G++ L+ V G + W + ++ + TF N L + K +
Sbjct: 2125 SRANTRVKAGDTAVLDCEVIGEPKPKIFWLLPSSDVISFSQDRYTFHPNG-SLSISKVKL 2183
Query: 1041 GDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLS-----CHV 1205
D+G Y C N +G S + + KPP+ + T TV + ++ S C
Sbjct: 2184 LDSGEYVCVARNPSGDDTKMSKLDV--VAKPPLINGLYTNKTVMKATAVRHSKKHFDCRA 2241
Query: 1206 RGSEPIRIQWLKAGREIKPSDRCSFSFA---NGTAVLEFKDVTKADAGDYVCKASNVAGS 1376
G+ +I W+ + NGT LE ++V +D+ D+ C A N G
Sbjct: 2242 EGTPSPQIMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFTCVARNEGGE 2299
Query: 1377 DTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVK 1556
S V + K+ + + K TA V G+P P +
Sbjct: 2300 --SVLVVQLEVLEMLRRPTFRNPFNEKI--------VAQLGKPTA-LNCSVDGNPPPEII 2348
Query: 1557 WTKGKWRQLNQGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVNE 1736
W Q G H I TT+ D+G YRC A NK G IE + L++ +
Sbjct: 2349 WILPNGTQFPNGPPNSQHLIASNGSFIIYKTTRDDAGKYRCGARNKVGYIEKLIVLEIGQ 2408
Query: 1737 R 1739
+
Sbjct: 2409 K 2409
Score = 121 bits (304), Expect = 1e-27
Identities = 141/591 (23%), Positives = 209/591 (35%), Gaps = 27/591 (4%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNV------ATLVFNQVDS 173
V A L C+ G PE + W TK+ P N+ TL +VD
Sbjct: 1639 VPANSDAFLPCEAVGNPEPTIHW----TKISPGLDLSKRNENSRFQVLPNGTLSIQKVDI 1694
Query: 174 NDSGEYICRAENSVGEVSSSTFLTVQEQKLPPS-FSRQLRDVQETVGLPVVFECAVSGSE 350
D G+Y+C A NS G + +T+ PP R+ +++ V +C V G
Sbjct: 1695 QDRGQYLCSASNSFG--TDRLHVTLSVVSYPPRILERRTKEITVHSRSTVKVKCRVEGRP 1752
Query: 351 PISVSWFKDGRPL--KDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSA 524
++SW + + K + + + TL I G Y C A+NP+G S
Sbjct: 1753 SPTISWILANQTVVSKSSEGNGQALVMSDGTLVIHNISIYDRGFYKCMASNPVGQDSLLI 1812
Query: 525 RLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQPIKVAWA-KDNREIRSGGNYQI 701
+ I P + + G+S C GT + W D E++
Sbjct: 1813 K-IQVIAAPPVILEQKRQVITGAWGKSLKLPCTAKGTPQPGIHWVLSDGTEVKPLQFINS 1871
Query: 702 SYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEE 881
+L ++ L I + DTG Y C A + G + L ++++ P + E
Sbjct: 1872 KFLFSNGTLLIRNMASSDTGTYECIATSSTGSERRVVILTVEDQETIPRIESASQKWTEV 1931
Query: 882 TEGNSFRLEGRVAGSQPISVAWYKNNVEI----HPTANCEITFKNNALLLQVKKASMGDA 1049
G+ L G + W + + H + + N +LL + + D+
Sbjct: 1932 NLGDKLLLNCSAIGEPKPKIIWRLPSKAVVDQWHRMGSRIHVYPNGSLL--IGSVTEKDS 1989
Query: 1050 GLYTCKVSNDAGSALCTSSIVIKEPKKPPVFD--QHLTPVTVSEGEFLQLSCHVRGSEPI 1223
G Y C N G L + ++ KP D QH G+ Q+ C GS
Sbjct: 1990 GDYLCVARNKMGDDLTLMHVSLR--WKPAKIDHKQHFRK-QAFHGKDFQVDCKASGSPLP 2046
Query: 1224 RIQW-LKAGREIKPSDRCSFS---------FANGTAVLEFKDVTKADAGDYVCKASNVAG 1373
I W L G I + + S F NGT L F V A+ GDY C A N G
Sbjct: 2047 EISWSLPDGTVINNAMQADDSGLRNRRFTLFDNGT--LYFNKVGMAEEGDYTCYAQNTLG 2104
Query: 1374 SDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNV 1553
D K +T + RV TA +V G+P P +
Sbjct: 2105 KDEMKVHLTVITAAPRIRQ-------------GSRANTRVKAGDTAVLDCEVIGEPKPKI 2151
Query: 1554 KWTKGKWRQLN-QGGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGE 1703
W ++ R H G L I DSG Y CVA N G+
Sbjct: 2152 FWLLPSSDVISFSQDRYTFHPNG---SLSISKVKLLDSGEYVCVARNPSGD 2199
Score = 113 bits (282), Expect = 4e-25
Identities = 116/473 (24%), Positives = 187/473 (39%), Gaps = 16/473 (3%)
Frame = +3
Query: 9 KVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGE 188
+V GD+A L C++ G P+ + W + + + + F N +L ++V DSGE
Sbjct: 2130 RVKAGDTAVLDCEVIGEPKPKIFWLLPSSDVISFSQDRYTFHPN-GSLSISKVKLLDSGE 2188
Query: 189 YICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPV-----VFECAVSGSEP 353
Y+C A N G+ + + L V + PP + + V F+C G+
Sbjct: 2189 YVCVARNPSGDDTKMSKLDVVAK--PPLINGLYTNKTVMKATAVRHSKKHFDCRAEGTPS 2246
Query: 354 ISVSWFKDGRPLKDGPNIQTSF-LDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
+ W P + + TL I S + ++C A N G + +L
Sbjct: 2247 PQIMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFTCVARNEGGESVLVVQL 2306
Query: 531 ILTEGRNPPFFDIPL-APVDAVVGESADFECHVTGTQPIKVAWAKDN-REIRSGGNYQIS 704
+ E P F P + A +G+ C V G P ++ W N + +G
Sbjct: 2307 EVLEMLRRPTFRNPFNEKIVAQLGKPTALNCSVDGNPPPEIIWILPNGTQFPNGPPNSQH 2366
Query: 705 YLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEET 884
+ ++ I K + D G+Y C A N+VG L I ++ I ++ + ETV
Sbjct: 2367 LIASNGSFIIYKTTRDDAGKYRCGARNKVGYIEKLIVLEIGQKPIILTYAR---ETVYCI 2423
Query: 885 EGNSFRLEGRVAGSQPISVAWY--KNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLY 1058
G+S L GS + W V P N + F N L+ +K A+ D G Y
Sbjct: 2424 SGDSLSLHCVSNGSPKPHIKWTVPSGYVLDRPQINGKYIFHENGTLV-IKDATAYDRGNY 2482
Query: 1059 TCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQW- 1235
CK N G A+ T +++ P + ++ + G LQL C G + W
Sbjct: 2483 ICKAQNSVGHAVITVPVMV-VAYPPRITNRLPRSIRTRTGVALQLPCVALGVPRPEVTWE 2541
Query: 1236 -----LKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSD 1379
L +G +I GT V++ + +D+G Y C A N GSD
Sbjct: 2542 MPDHSLFSGADIGRMSGIQSFHPRGTLVIQ--NPQTSDSGIYKCTAKNPLGSD 2592
Score = 63.5 bits (153), Expect = 4e-10
Identities = 60/276 (21%), Positives = 103/276 (37%), Gaps = 7/276 (2%)
Frame = +3
Query: 18 VGDSASLQCQLAGTPEIGVSWY-KGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEYI 194
+G +L C + G P + W T+ H + + + + +D+G+Y
Sbjct: 2329 LGKPTALNCSVDGNPPPEIIWILPNGTQFPNGPPNSQHLIASNGSFIIYKTTRDDAGKYR 2388
Query: 195 CRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWFK 374
C A N VG + L + ++ + +++R+ V G + C +GS + W
Sbjct: 2389 CGARNKVGYIEKLIVLEIGQKPIILTYARET--VYCISGDSLSLHCVSNGSPKPHIKWTV 2446
Query: 375 DGRPLKDGPNIQTSFLDNV-ATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
+ D P I ++ + TL I G Y C A N +G A + +++
Sbjct: 2447 PSGYVLDRPQINGKYIFHENGTLVIKDATAYDRGNYICKAQNSVGHAVITVPVMVVA--Y 2504
Query: 552 PPFFDIPLA-PVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAH- 725
PP L + G + C G +V W + + SG + S H
Sbjct: 2505 PPRITNRLPRSIRTRTGVALQLPCVALGVPRPEVTWEMPDHSLFSGADIGRMSGIQSFHP 2564
Query: 726 ---LTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI 824
L I D+G Y C A N +G D T + +
Sbjct: 2565 RGTLVIQNPQTSDSGIYKCTAKNPLGSDYATTYIQV 2600
Score = 55.8 bits (133), Expect = 8e-08
Identities = 44/182 (24%), Positives = 70/182 (38%), Gaps = 8/182 (4%)
Frame = +3
Query: 306 VGLPVVFECAVSGSEPISVSWFKDGRPLKDGPNIQTSF--------LDNVATLNIFQTDR 461
VG + +C G P + W L DG ++ + +D L + D
Sbjct: 488 VGGTIGLDCPGQGDPPPHLEWL-----LADGSKVRAPYVSEDGRILIDKSGKLELQMADI 542
Query: 462 SFAGQYSCTATNPIGSASSSARLILTEGRNPPFFDIPLAPVDAVVGESADFECHVTGTQP 641
G Y C +TN + + R+ + E P+ + + GE+ D CH TG
Sbjct: 543 FDTGIYHCISTNYDDADFLTYRITVIEPSIEPYQENGAHHI-VPSGETLDLPCHSTGIPD 601
Query: 642 IKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLN 821
V+W + + L N L IL+V + D G Y C A N G D Q++
Sbjct: 602 ASVSWVLPGNSVLQQSSRDKKILNNGT-LRILQVTQKDQGHYRCVAANPSGVDFLINQVS 660
Query: 822 IK 827
++
Sbjct: 661 VQ 662
>ref|XP_003130435.2| PREDICTED: hemicentin-1-like [Sus scrofa].
Length = 780
Score = 129 bits (323), Expect = 8e-30
Identities = 119/436 (27%), Positives = 175/436 (40%), Gaps = 24/436 (5%)
Frame = +3
Query: 147 TLVFNQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSF--SRQLRDVQETVGLPV 320
TL Q D+G+Y C N+ GE + L+V +PP L DV+ V
Sbjct: 324 TLRLMQTKIEDAGQYTCIVRNAAGEERKTFGLSVL---VPPHIVGENTLEDVKVKEKQNV 380
Query: 321 VFECAVSGSEPISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNP 500
C V+G+ ++W KDG+ LK+ + L I S G+Y+C A+N
Sbjct: 381 TLTCEVTGNPMPEITWQKDGQLLKEDNTHH--LMSGGRFLQITNAQVSHTGRYTCLASNT 438
Query: 501 IGSASSSARLILTEGRNPPFFDIPLAPVDA--VVGESADFECHVTGTQPIKVAWAKDNRE 674
G S S L + D +P D ++ C P + W K+
Sbjct: 439 AGDKSKSFSLNVLVSPTIAGVDSDGSPEDVSVILNSPTSLVCEAFSYPPAIITWFKNGTP 498
Query: 675 IRSGGNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNI-------KER 833
+ S N +I L L IL + + G+Y+C A NE G+ ++ + K
Sbjct: 499 LESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGD 556
Query: 834 LIPPSFTKKLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNAL 1013
L+ P + K V+ N+ LE S++WYK+ + ++ +T N
Sbjct: 557 LLGPGLSPK---EVKIKVNNTLTLECEAYAVPSASLSWYKDGQPLK--SDDHVTIAANGH 611
Query: 1014 LLQVKKASMGDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPV-----TVSEG 1178
LQ+K+A + D G YTC SN AG + I + PP F Q L + T G
Sbjct: 612 TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNI---QVPPSF-QKLWEIGNMLDTGRRG 667
Query: 1179 EF--------LQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKAD 1334
E + L C + P + W K G + SDR G VL+ D
Sbjct: 668 EAKDVIISNPISLYCETNAAPPPTLTWYKDGHPLTSSDR--VLILPGGRVLQIPRARVED 725
Query: 1335 AGDYVCKASNVAGSDT 1382
AG YVC A N AG D+
Sbjct: 726 AGRYVCVAVNEAGEDS 741
Score = 128 bits (321), Expect = 1e-29
Identities = 104/385 (27%), Positives = 159/385 (41%), Gaps = 25/385 (6%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSG 185
VKV + +L C++ G P ++W K L+ T+ H + L + +G
Sbjct: 372 VKVKEKQNVTLTCEVTGNPMPEITWQKDGQLLKEDNTH--HLMSGGRFLQITNAQVSHTG 429
Query: 186 EYICRAENSVGEVSSSTFLTVQEQKLPPSFS-----RQLRDVQETVGLPVVFECAVSGSE 350
Y C A N+ G+ S S L V + P+ + DV + P C
Sbjct: 430 RYTCLASNTAGDKSKSFSLNV---LVSPTIAGVDSDGSPEDVSVILNSPTSLVCEAFSYP 486
Query: 351 PISVSWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARL 530
P ++WFK+G PL+ NI+ L TL I AG+YSC ATN G +
Sbjct: 487 PAIITWFKNGTPLESNRNIR--ILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEV 544
Query: 531 ------ILTEGRNPPFFDIPLAP--VDAVVGESADFECHVTGTQPIKVAWAKDNREIRSG 686
I+ +G L+P V V + EC ++W KD + ++S
Sbjct: 545 KVYIPPIINKG---DLLGPGLSPKEVKIKVNNTLTLECEAYAVPSASLSWYKDGQPLKSD 601
Query: 687 GNYQISYLENSAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK--- 857
+ I+ N L I + DTG+YTC A N G+D +NI+ +PPSF K
Sbjct: 602 DHVTIA--ANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ---VPPSFQKLWE 656
Query: 858 --------KLSETVEETEGNSFRLEGRVAGSQPISVAWYKNNVEIHP-TANCEITFKNNA 1010
+ E + N L + P ++ WYK+ HP T++ +
Sbjct: 657 IGNMLDTGRRGEAKDVIISNPISLYCETNAAPPPTLTWYKDG---HPLTSSDRVLILPGG 713
Query: 1011 LLLQVKKASMGDAGLYTCKVSNDAG 1085
+LQ+ +A + DAG Y C N+AG
Sbjct: 714 RVLQIPRARVEDAGRYVCVAVNEAG 738
Score = 114 bits (285), Expect = 2e-25
Identities = 133/587 (22%), Positives = 213/587 (36%), Gaps = 12/587 (2%)
Frame = +3
Query: 6 VKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYK-MHFRNNVATLVFNQVDSNDS 182
+ V +S SL C+ +G P ++W K L +++ + + +N TL+ +
Sbjct: 217 ISVVEKNSVSLTCEASGIPLPSITWLKDGWPLNLSSSLRILSGISNSYTLIICVM----- 271
Query: 183 GEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISV 362
Y+ R + ++ QE P FS +V+ E
Sbjct: 272 --YLSRKQMQFFHMNKMFSPVTQE----PVFSTSKLEVERVASQSYTHE----------- 314
Query: 363 SWFKDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTE 542
+ GR + TL + QT AGQY+C N G + L +
Sbjct: 315 ---RGGRH------------ERGRTLRLMQTKIEDAGQYTCIVRNAAGEERKTFGLSVLV 359
Query: 543 GRNPPFF--DIPLAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLEN 716
PP + L V ++ C VTG ++ W KD + ++ + + +
Sbjct: 360 ---PPHIVGENTLEDVKVKEKQNVTLTCEVTGNPMPEITWQKDGQLLKEDNTHHL--MSG 414
Query: 717 SAHLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLS----ETVEET 884
L I TG+YTC A N G S + LN+ L+ P+ S E V
Sbjct: 415 GRFLQITNAQVSHTGRYTCLASNTAGDKSKSFSLNV---LVSPTIAGVDSDGSPEDVSVI 471
Query: 885 EGNSFRLEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTC 1064
+ L P + W+KN + N I LQ+ A +AG Y+C
Sbjct: 472 LNSPTSLVCEAFSYPPAIITWFKNGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSC 529
Query: 1065 KVSNDAGSALCTSSIVIKEP---KKPPVFDQHLTP--VTVSEGEFLQLSCHVRGSEPIRI 1229
+N+AG + + + P K + L+P V + L L C +
Sbjct: 530 VATNEAGEMIKHYEVKVYIPPIINKGDLLGPGLSPKEVKIKVNNTLTLECEAYAVPSASL 589
Query: 1230 QWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXX 1409
W K G+ +K D + + ANG L+ K+ +D G Y C ASN+AG D V
Sbjct: 590 SWYKDGQPLKSDDHVTIA-ANGHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQV 647
Query: 1410 XXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQ 1589
+ L ++ V+ + + P P + W K L
Sbjct: 648 PPSFQKLWE---IGNMLDTGRRGEAKDVIISNPISLYCETNAAPPPTLTWYKDG-HPLTS 703
Query: 1590 GGRIFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
R+ I G L+I D+G Y CVA N+ GE +++V
Sbjct: 704 SDRVLILPGG--RVLQIPRARVEDAGRYVCVAVNEAGEDSLQYDVRV 748
Score = 109 bits (272), Expect = 6e-24
Identities = 133/577 (23%), Positives = 214/577 (37%), Gaps = 4/577 (0%)
Frame = +3
Query: 12 VTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATYKMHFRNNVATLVFNQVDSNDSGEY 191
V G SL C+ +G P + W K + + + ++ + L + + +D+G Y
Sbjct: 29 VIEGHLISLLCESSGIPPPNLIWKKKGSPVLADSAGRVRTLSGGRQLQISIAEKSDAGLY 88
Query: 192 ICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWF 371
C A N G L V Q + ++ T G + EC V G +V+W
Sbjct: 89 TCVASNVAGTAKKDYNLQVYIQPTIANSGSHPTEIIITRGKSISLECEVQGIPQPTVTWM 148
Query: 372 KDGRPLKDGPNIQTSFLDNVATLNIFQTDRSFAGQYSCTATNPIGSASSSARLILTEGRN 551
KDGRPL ++ + D L + S G+Y C A N G + + L+
Sbjct: 149 KDGRPLTKERGMEIT--DEGRILQLKNVHVSDTGRYVCVAMNIAG--MTDRKYDLSVHTP 204
Query: 552 PPFFDIPLAP--VDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQI-SYLENSA 722
P P + V S C +G + W KD + + +I S + NS
Sbjct: 205 PSIIGSHRTPENISVVEKNSVSLTCEASGIPLPSITWLKDGWPLNLSSSLRILSGISNSY 264
Query: 723 HLTILKVDKGDTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFR 902
L I C L+ K+ K S +E ++ +
Sbjct: 265 TLII-----------------------CVMYLSRKQMQF-FHMNKMFSPVTQEPVFSTSK 300
Query: 903 LEGRVAGSQPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDA 1082
LE SQ + H L++ + + DAG YTC V N A
Sbjct: 301 LEVERVASQSYT----------HERGGRH----ERGRTLRLMQTKIEDAGQYTCIVRNAA 346
Query: 1083 GSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKP 1262
G T + + P V + L V V E + + L+C V G+ I W K G+ +K
Sbjct: 347 GEERKTFGLSVLVPPH-IVGENTLEDVKVKEKQNVTLTCEVTGNPMPEITWQKDGQLLKE 405
Query: 1263 SDRCSFSFANGTAVLEFKDVTKADAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXX 1442
+ + +G L+ + + G Y C ASN AG D SKS
Sbjct: 406 DN--THHLMSGGRFLQITNAQVSHTGRYTCLASNTAG-DKSKS-----FSLNVLVSPTIA 457
Query: 1443 XVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK-GKWRQLNQGGRIFIHQKG 1619
VD P+ + V+ + + + + P + W K G + N+ RI +
Sbjct: 458 GVDSD----GSPEDVSVILNSPTSLVCEAFSYPPAIITWFKNGTPLESNRNIRILPGGR- 512
Query: 1620 DEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQV 1730
L+I + + ++G Y CVA N+ GE+ + ++V
Sbjct: 513 ---TLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKV 546
Score = 80.9 bits (198), Expect = 2e-15
Identities = 63/229 (27%), Positives = 88/229 (38%), Gaps = 4/229 (1%)
Frame = +3
Query: 573 LAPVDAVVGESADFECHVTGTQPIKVAWAKDNREIRSGGNYQISYLENSAHLTILKVDKG 752
LA + + G C +G P + W K + + ++ L L I +K
Sbjct: 24 LAQLTVIEGHLISLLCESSGIPPPNLIWKKKGSPVLADSAGRVRTLSGGRQLQISIAEKS 83
Query: 753 DTGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVE--ETEGNSFRLEGRVAGS 926
D G YTC A N G L + I P+ S E T G S LE V G
Sbjct: 84 DAGLYTCVASNVAGTAKKDYNLQV---YIQPTIANSGSHPTEIIITRGKSISLECEVQGI 140
Query: 927 QPISVAWYKNNVEIHPTANCEITFKNNALLLQVKKASMGDAGLYTCKVSNDAGSALCTSS 1106
+V W K+ + EIT + +LQ+K + D G Y C N AG
Sbjct: 141 PQPTVTWMKDGRPLTKERGMEIT--DEGRILQLKNVHVSDTGRYVCVAMNIAGMTDRKYD 198
Query: 1107 IVIKEPKKPPVFDQHLTP--VTVSEGEFLQLSCHVRGSEPIRIQWLKAG 1247
+ + P P + H TP ++V E + L+C G I WLK G
Sbjct: 199 LSVHTP--PSIIGSHRTPENISVVEKNSVSLTCEASGIPLPSITWLKDG 245
Score = 62.8 bits (151), Expect = 7e-10
Identities = 54/199 (27%), Positives = 78/199 (39%), Gaps = 5/199 (2%)
Frame = +3
Query: 1152 LTPVTVSEGEFLQLSCHVRGSEPIRIQWLKAGREIKPSDRCSFSFANGTAVLEFKDVTKA 1331
L +TV EG + L C G P + W K G + +G L+ K+
Sbjct: 24 LAQLTVIEGHLISLLCESSGIPPPNLIWKKKGSPVLADSAGRVRTLSGGRQLQISIAEKS 83
Query: 1332 DAGDYVCKASNVAGSDTSKSKVTXXXXXXXXXXXXXXXVDGKLFFVSEPQSIRVVEKTTA 1511
DAG Y C ASNVAG T+K S P I + +
Sbjct: 84 DAGLYTCVASNVAG--TAKKDYNLQVYIQPTIANSG----------SHPTEIIITRGKSI 131
Query: 1512 TFIAKVGGDPIPNVKWTKGKWRQLNQGGRIFIHQKG----DEAK-LEIRDTTKTDSGLYR 1676
+ +V G P P V W K GR ++G DE + L++++ +D+G Y
Sbjct: 132 SLECEVQGIPQPTVTWMKD--------GRPLTKERGMEITDEGRILQLKNVHVSDTGRYV 183
Query: 1677 CVAFNKHGEIESNVNLQVN 1733
CVA N G + +L V+
Sbjct: 184 CVAMNIAGMTDRKYDLSVH 202
Database: RefSeq49_SP.fasta
Posted date: Oct 17, 2011 1:42 PM
Number of letters in database: 11,343,932
Number of sequences in database: 24,897
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 24897
Number of Hits to DB: 46,491,580
Number of extensions: 1199363
Number of successful extensions: 7098
Number of sequences better than 1.0e-05: 111
Number of HSP's gapped: 4799
Number of HSP's successfully gapped: 513
Length of query: 667
Length of database: 11,343,932
Length adjustment: 106
Effective length of query: 561
Effective length of database: 8,704,850
Effective search space: 4883420850
Effective search space used: 4883420850
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 35 (18.1 bits)
BLASTN 2.2.24 [Aug-08-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MLTL1_0024_C11
(2001 letters)
Database: Sscrofa_10.2.fasta
4582 sequences; 2,808,509,378 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Sscrofa_Chr15 581 e-163
>Sscrofa_Chr15
|| Length = 157681621
Score = 581 bits (293), Expect = e-163
Identities = 293/293 (100%)
Strand = Plus / Minus
Query: 827 agagcggctaatcccaccaagtttcactaaaaaactctcggagacagtagaagaaacaga 886
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93899467 agagcggctaatcccaccaagtttcactaaaaaactctcggagacagtagaagaaacaga 93899408
Query: 887 agggaattccttcagacttgagggccgagttgctggttcccagcccatcagtgttgcttg 946
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93899407 agggaattccttcagacttgagggccgagttgctggttcccagcccatcagtgttgcttg 93899348
Query: 947 gtacaaaaataatgtagagatccatccaacggccaattgtgaaatcacattcaagaacaa 1006
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93899347 gtacaaaaataatgtagagatccatccaacggccaattgtgaaatcacattcaagaacaa 93899288
Query: 1007 tgcacttctgctgcaagtcaagaaggcaagcatgggcgatgctggtttgtacacgtgcaa 1066
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93899287 tgcacttctgctgcaagtcaagaaggcaagcatgggcgatgctggtttgtacacgtgcaa 93899228
Query: 1067 agtgtcgaatgacgcaggctctgctctgtgtacgtcttcaatcgtcatcaaag 1119
|||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93899227 agtgtcgaatgacgcaggctctgctctgtgtacgtcttcaatcgtcatcaaag 93899175
Score = 575 bits (290), Expect = e-161
Identities = 290/290 (100%)
Strand = Plus / Minus
Query: 1118 agaacctaagaagccccctgtgtttgatcagcatctgactccagtaacagtgagtgaagg 1177
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93897457 agaacctaagaagccccctgtgtttgatcagcatctgactccagtaacagtgagtgaagg 93897398
Query: 1178 agaattcctgcagctcagctgccacgtccggggatcagaacccatcaggatccagtggtt 1237
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93897397 agaattcctgcagctcagctgccacgtccggggatcagaacccatcaggatccagtggtt 93897338
Query: 1238 gaaggctggcagggaaataaagccctcagacagatgcagcttcagctttgctaatgggac 1297
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93897337 gaaggctggcagggaaataaagccctcagacagatgcagcttcagctttgctaatgggac 93897278
Query: 1298 cgctgtgctggaattcaaggatgtaactaaagcagatgcgggagattatgtgtgtaaagc 1357
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93897277 cgctgtgctggaattcaaggatgtaactaaagcagatgcgggagattatgtgtgtaaagc 93897218
Query: 1358 ttcaaatgtggctggaagtgacacttccaaatcaaaagtgaccattaaag 1407
||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93897217 ttcaaatgtggctggaagtgacacttccaaatcaaaagtgaccattaaag 93897168
Score = 575 bits (290), Expect = e-161
Identities = 290/290 (100%)
Strand = Plus / Minus
Query: 539 agaggggaggaacccgcctttctttgacatccctcttgcccctgtggatgctgtggtggg 598
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93900170 agaggggaggaacccgcctttctttgacatccctcttgcccctgtggatgctgtggtggg 93900111
Query: 599 agagagtgcggactttgagtgccacgttactgggacacaaccgataaaggtcgcctgggc 658
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93900110 agagagtgcggactttgagtgccacgttactgggacacaaccgataaaggtcgcctgggc 93900051
Query: 659 caaagacaacagagagatccgaagtggtggaaactaccagattagttatctggaaaacag 718
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93900050 caaagacaacagagagatccgaagtggtggaaactaccagattagttatctggaaaacag 93899991
Query: 719 tgcccacctgacaatcctgaaagtagacaaaggcgacactggacagtatacctgctatgc 778
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93899990 tgcccacctgacaatcctgaaagtagacaaaggcgacactggacagtatacctgctatgc 93899931
Query: 779 tgtcaatgaagtgggcaaggactcctgcacggctcagctcaatataaaag 828
||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93899930 tgtcaatgaagtgggcaaggactcctgcacggctcagctcaatataaaag 93899881
Score = 567 bits (286), Expect = e-159
Identities = 289/290 (99%)
Strand = Plus / Minus
Query: 251 agagcaaaaacttccaccatcattttcacgacaactgagagatgttcaagaaacagtcgg 310
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93900853 agagcaaaaacttccaccatcattttcacgacaactgagagatgttcaagaaacagtcgg 93900794
Query: 311 gctgccagttgtttttgaatgtgccgtcagtggatcagaacctatatcggtgtcttggtt 370
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93900793 gctgccagttgtttttgaatgtgccgtcagtggatcagaacctatatcggtgtcttggtt 93900734
Query: 371 taaagatggcaggcccttgaaagatggccccaacatccagacatcatttttagataacgt 430
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93900733 taaagatggcaggcccttgaaagatggccccaacatccagacatcatttttagataacgt 93900674
Query: 431 agccactctcaatatttttcaaacagatcggagttttgcaggccagtattcctgcacagc 490
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93900673 agccactctcaatatttttcaaacagatcggagttttgcaggccagtattcctgcacagc 93900614
Query: 491 tacaaatcctataggttccgcttcttccagcgccagactcattctcacag 540
||||||||||||||||||||||||||||||||||||||| ||||||||||
Sbjct: 93900613 tacaaatcctataggttccgcttcttccagcgccagactgattctcacag 93900564
Score = 484 bits (244), Expect = e-133
Identities = 250/252 (99%)
Strand = Plus / Minus
Query: 1 agcctgtgaaggtgactgttggagattctgcctctttgcagtgtcagcttgctgggaccc 60
||||||||||||||||||||||||||||||||||||||||||| || |||||||||||||
Sbjct: 93901705 agcctgtgaaggtgactgttggagattctgcctctttgcagtgccaacttgctgggaccc 93901646
Query: 61 ctgaaattggggtgtcctggtataaaggagatacaaaactgagacccactgccacctaca 120
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93901645 ctgaaattggggtgtcctggtataaaggagatacaaaactgagacccactgccacctaca 93901586
Query: 121 agatgcattttaggaacaacgttgcaacactggttttcaaccaggtcgatagtaacgaca 180
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93901585 agatgcattttaggaacaacgttgcaacactggttttcaaccaggtcgatagtaacgaca 93901526
Query: 181 gtggagaatatatctgcagagctgaaaacagtgtgggagaagtttcttcatcaactttcc 240
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93901525 gtggagaatatatctgcagagctgaaaacagtgtgggagaagtttcttcatcaactttcc 93901466
Query: 241 tgaccgttcaag 252
||||||||||||
Sbjct: 93901465 tgaccgttcaag 93901454
Score = 474 bits (239), Expect = e-131
Identities = 242/243 (99%)
Strand = Plus / Minus
Query: 1545 ccaaatgtcaaatggacaaaggggaagtggagacagctgaaccaaggaggtcgaattttt 1604
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93896186 ccaaatgtcaaatggacaaaggggaagtggagacagctgaaccaaggaggtcgaattttt 93896127
Query: 1605 atccaccagaaaggcgatgaagcaaaactggagattagagacaccacaaaaaccgattct 1664
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93896126 atccaccagaaaggcgatgaagcaaaactggagattagagacaccacaaaaaccgattct 93896067
Query: 1665 ggattataccgatgtgtcgcgtttaataaacatggtgaaattgaaagtaatgttaaccta 1724
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93896066 ggattataccgatgtgtcgcgtttaataaacatggtgaaattgaaagtaatgttaaccta 93896007
Query: 1725 caggtgaatgaaaggaagaaacaagagaaaattgaaggagaccttagggcaatgctgaaa 1784
|||||| |||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93896006 caggtggatgaaaggaagaaacaagagaaaattgaaggagaccttagggcaatgctgaaa 93895947
Query: 1785 aag 1787
|||
Sbjct: 93895946 aag 93895944
Score = 363 bits (183), Expect = 2e-97
Identities = 183/183 (100%)
Strand = Plus / Minus
Query: 1787 gactccagtcttaaagaaaggagctggggaagaagaggaaattgatatcatggaacttct 1846
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93895154 gactccagtcttaaagaaaggagctggggaagaagaggaaattgatatcatggaacttct 93895095
Query: 1847 caaaaatgttgatccaaaagaatatgaaaaatatgcccgcatgtacggaatcaccgactt 1906
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93895094 caaaaatgttgatccaaaagaatatgaaaaatatgcccgcatgtacggaatcaccgactt 93895035
Query: 1907 ccgaggtcttcttcaggcatttgaaatgctaaagcaaagccaagaagaagagactcatag 1966
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93895034 ccgaggtcttcttcaggcatttgaaatgctaaagcaaagccaagaagaagagactcatag 93894975
Query: 1967 att 1969
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Sbjct: 93894974 att 93894972
Score = 188 bits (95), Expect = 8e-45
Identities = 95/95 (100%)
Strand = Plus / Minus
Query: 1406 agacaaaccagctgccatcccagcagctaagaaagcagcagtagatggaaagctcttctt 1465
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Sbjct: 93896604 agacaaaccagctgccatcccagcagctaagaaagcagcagtagatggaaagctcttctt 93896545
Query: 1466 cgtatcagaacctcagagtatcagagttgtagaaa 1500
|||||||||||||||||||||||||||||||||||
Sbjct: 93896544 cgtatcagaacctcagagtatcagagttgtagaaa 93896510
Score = 178 bits (90), Expect = 8e-42
Identities = 90/90 (100%)
Strand = Plus / Minus
Query: 1501 aaaccactgcaaccttcattgcaaaagttggaggtgacccaattccaaatgtcaaatgga 1560
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Sbjct: 93896388 aaaccactgcaaccttcattgcaaaagttggaggtgacccaattccaaatgtcaaatgga 93896329
Query: 1561 caaaggggaagtggagacagctgaaccaag 1590
||||||||||||||||||||||||||||||
Sbjct: 93896328 caaaggggaagtggagacagctgaaccaag 93896299
Database: Sscrofa_10.2.fasta
Posted date: Nov 16, 2011 10:34 AM
Number of letters in database: 2,808,509,378
Number of sequences in database: 4582
Lambda K H
1.37 0.711 1.31
Gapped
Lambda K H
1.37 0.711 1.31
Matrix: blastn matrix:1 -3
Gap Penalties: Existence: 5, Extension: 2
Number of Sequences: 4582
Number of Hits to DB: 66,307,596
Number of extensions: 613
Number of successful extensions: 613
Number of sequences better than 1.0e-05: 1
Number of HSP's gapped: 613
Number of HSP's successfully gapped: 9
Length of query: 2001
Length of database: 2,808,509,378
Length adjustment: 22
Effective length of query: 1979
Effective length of database: 2,808,408,574
Effective search space: 5557840567946
Effective search space used: 5557840567946
X1: 11 (21.8 bits)
X2: 15 (29.7 bits)
X3: 50 (99.1 bits)
S1: 18 (36.2 bits)
S2: 30 (60.0 bits)